Device for modular input high-speed multi-channel digitizing of electrical data

DOEpatents

VanDeusen, Alan L.; Crist, Charles E.

1995-09-26

A multi-channel high-speed digitizer module converts a plurality of analog signals to digital signals (digitizing) and stores the signals in a memory device. The analog input channels are digitized simultaneously at high speed with a relatively large number of on-board memory data points per channel. The module provides an automated calibration based upon a single voltage reference source. Low signal noise at such a high density and sample rate is accomplished by ensuring the A/D converters are clocked at the same point in the noise cycle each time so that synchronous noise sampling occurs. This sampling process, in conjunction with an automated calibration, yields signal noise levels well below the noise level present on the analog reference voltages.

Digital Advances in Contemporary Audio Production.

ERIC Educational Resources Information Center

Shields, Steven O.

Noting that a revolution in sonic high fidelity occurred during the 1980s as digital-based audio production methods began to replace traditional analog modes, this paper offers both an overview of digital audio theory and descriptions of some of the related digital production technologies that have begun to emerge from the mating of the computer…

Using Digital Technologies to Improve the Authenticity of Performance Assessment for High-Stakes Purposes

ERIC Educational Resources Information Center

Newhouse, C. Paul

2015-01-01

This paper reports on the outcomes of a three-year study investigating the use of digital technologies to increase the authenticity of high-stakes summative assessment in four Western Australian senior secondary courses. The study involved 82 teachers and 1015 students and a range of digital forms of assessment using computer-based exams, digital…

Mutation Testing for Effective Verification of Digital Components of Physical Systems

NASA Astrophysics Data System (ADS)

Kushik, N. G.; Evtushenko, N. V.; Torgaev, S. N.

2015-12-01

Digital components of modern physical systems are often designed applying circuitry solutions based on the field programmable gate array technology (FPGA). Such (embedded) digital components should be carefully tested. In this paper, an approach for the verification of digital physical system components based on mutation testing is proposed. The reference description of the behavior of a digital component in the hardware description language (HDL) is mutated by introducing into it the most probable errors and, unlike mutants in high-level programming languages, the corresponding test case is effectively derived based on a comparison of special scalable representations of the specification and the constructed mutant using various logic synthesis and verification systems.

Advanced digital signal processing for short-haul and access network

NASA Astrophysics Data System (ADS)

Zhang, Junwen; Yu, Jianjun; Chi, Nan

2016-02-01

Digital signal processing (DSP) has been proved to be a successful technology recently in high speed and high spectrum-efficiency optical short-haul and access network, which enables high performances based on digital equalizations and compensations. In this paper, we investigate advanced DSP at the transmitter and receiver side for signal pre-equalization and post-equalization in an optical access network. A novel DSP-based digital and optical pre-equalization scheme has been proposed for bandwidth-limited high speed short-distance communication system, which is based on the feedback of receiver-side adaptive equalizers, such as least-mean-squares (LMS) algorithm and constant or multi-modulus algorithms (CMA, MMA). Based on this scheme, we experimentally demonstrate 400GE on a single optical carrier based on the highest ETDM 120-GBaud PDM-PAM-4 signal, using one external modulator and coherent detection. A line rate of 480-Gb/s is achieved, which enables 20% forward-error correction (FEC) overhead to keep the 400-Gb/s net information rate. The performance after fiber transmission shows large margin for both short range and metro/regional networks. We also extend the advanced DSP for short haul optical access networks by using high order QAMs. We propose and demonstrate a high speed multi-band CAP-WDM-PON system on intensity modulation, direct detection and digital equalizations. A hybrid modified cascaded MMA post-equalization schemes are used to equalize the multi-band CAP-mQAM signals. Using this scheme, we successfully demonstrates 550Gb/s high capacity WDMPON system with 11 WDM channels, 55 sub-bands, and 10-Gb/s per user in the downstream over 40-km SMF.

Development of a digital method for neutron/gamma-ray discrimination based on matched filtering

NASA Astrophysics Data System (ADS)

Korolczuk, S.; Linczuk, M.; Romaniuk, R.; Zychor, I.

2016-09-01

Neutron/gamma-ray discrimination is crucial for measurements with detectors sensitive to both neutron and gamma-ray radiation. Different techniques to discriminate between neutrons and gamma-rays based on pulse shape analysis are widely used in many applications, e.g., homeland security, radiation dosimetry, environmental monitoring, fusion experiments, nuclear spectroscopy. A common requirement is to improve a radiation detection level with a high detection reliability. Modern electronic components, such as high speed analog to digital converters and powerful programmable digital circuits for signal processing, allow us to develop a fully digital measurement system. With this solution it is possible to optimize digital signal processing algorithms without changing any electronic components in an acquisition signal path. We report on results obtained with a digital acquisition system DNG@NCBJ designed at the National Centre for Nuclear Research. A 2'' × 2'' EJ309 liquid scintillator was used to register mixed neutron and gamma-ray radiation from PuBe sources. A dedicated algorithm for pulse shape discrimination, based on real-time filtering, was developed and implemented in hardware.

An all-digital phase-locked loop demodulator based on FPGA

NASA Astrophysics Data System (ADS)

Gong, X. F.; Cui, Z. D.

2017-09-01

This paper studied the principle of analogue phase-locked loop demodulation and work process of digital phase-locked loop. It is found that the higher the reference signal frequency is, the smaller the duty ratio of the discriminator output signal is. Carrier detection is achieved by using this relationship. The experimental results indicate that the demodulator based on the principle could realize high-quality transmission of digital signals and could be an effective FM communication mode for studying wireless transmission of digital signals.

Signal digitizing system and method based on amplitude-to-time optical mapping

DOEpatents

Chou, Jason; Bennett, Corey V; Hernandez, Vince

2015-01-13

A signal digitizing system and method based on analog-to-time optical mapping, optically maps amplitude information of an analog signal of interest first into wavelength information using an amplitude tunable filter (ATF) to impress spectral changes induced by the amplitude of the analog signal onto a carrier signal, i.e. a train of optical pulses, and next from wavelength information to temporal information using a dispersive element so that temporal information representing the amplitude information is encoded in the time domain in the carrier signal. Optical-to-electrical conversion of the optical pulses into voltage waveforms and subsequently digitizing the voltage waveforms into a digital image enables the temporal information to be resolved and quantized in the time domain. The digital image may them be digital signal processed to digitally reconstruct the analog signal based on the temporal information with high fidelity.

Dual-energy contrast-enhanced digital mammography (DE-CEDM): optimization on digital subtraction with practical x-ray low/high-energy spectra

NASA Astrophysics Data System (ADS)

Chen, Biao; Jing, Zhenxue; Smith, Andrew P.; Parikh, Samir; Parisky, Yuri

2006-03-01

Dual-energy contrast enhanced digital mammography (DE-CEDM), which is based upon the digital subtraction of low/high-energy image pairs acquired before/after the administration of contrast agents, may provide physicians physiologic and morphologic information of breast lesions and help characterize their probability of malignancy. This paper proposes to use only one pair of post-contrast low / high-energy images to obtain digitally subtracted dual-energy contrast-enhanced images with an optimal weighting factor deduced from simulated characteristics of the imaging chain. Based upon our previous CEDM framework, quantitative characteristics of the materials and imaging components in the x-ray imaging chain, including x-ray tube (tungsten) spectrum, filters, breast tissues / lesions, contrast agents (non-ionized iodine solution), and selenium detector, were systemically modeled. Using the base-material (polyethylene-PMMA) decomposition method based on entrance low / high-energy x-ray spectra and breast thickness, the optimal weighting factor was calculated to cancel the contrast between fatty and glandular tissues while enhancing the contrast of iodized lesions. By contrast, previous work determined the optimal weighting factor through either a calibration step or through acquisition of a pre-contrast low/high-energy image pair. Computer simulations were conducted to determine weighting factors, lesions' contrast signal values, and dose levels as functions of x-ray techniques and breast thicknesses. Phantom and clinical feasibility studies were performed on a modified Selenia full field digital mammography system to verify the proposed method and computer-simulated results. The resultant conclusions from the computer simulations and phantom/clinical feasibility studies will be used in the upcoming clinical study.

Device for modular input high-speed multi-channel digitizing of electrical data

DOEpatents

VanDeusen, A.L.; Crist, C.E.

1995-09-26

A multi-channel high-speed digitizer module converts a plurality of analog signals to digital signals (digitizing) and stores the signals in a memory device. The analog input channels are digitized simultaneously at high speed with a relatively large number of on-board memory data points per channel. The module provides an automated calibration based upon a single voltage reference source. Low signal noise at such a high density and sample rate is accomplished by ensuring the A/D converters are clocked at the same point in the noise cycle each time so that synchronous noise sampling occurs. This sampling process, in conjunction with an automated calibration, yields signal noise levels well below the noise level present on the analog reference voltages. 1 fig.

Are There Jewish Digital Badges?: A Study of Religious Middle- and High-School Girls' Perception of an Emerging Educational Technology-Based Assessment

ERIC Educational Resources Information Center

Abramovich, Samuel

2017-01-01

For Jewish education, digital badges can provide an alternative to traditional assessments. However, the emerging research on badges suggests a complex relationship between learning opportunities, the learner, and the design of the badge. An investigation of a digital badge system at an ultra-Orthodox Jewish middle and high school for girls…

Teachers' Dispositions towards the Role of Digital Devices in Play-Based Pedagogy in Early Childhood Education

ERIC Educational Resources Information Center

Palaiologou, Ioanna

2016-01-01

A body of research is emerging on early childhood education teachers' views on the integration of digital technologies in their practice. Despite evidence of the digitalisation of homes in affluent societies and children's interactions in highly mediated digital environments, few teachers so far have integrated digital devices into a play-based…

Superconductor Digital Electronics: -- Current Status, Future Prospects

NASA Astrophysics Data System (ADS)

Mukhanov, Oleg

2011-03-01

Two major applications of superconductor electronics: communications and supercomputing will be presented. These areas hold a significant promise of a large impact on electronics state-of-the-art for the defense and commercial markets stemming from the fundamental advantages of superconductivity: simultaneous high speed and low power, lossless interconnect, natural quantization, and high sensitivity. The availability of relatively small cryocoolers lowered the foremost market barrier for cryogenically-cooled superconductor electronic systems. These fundamental advantages enabled a novel Digital-RF architecture - a disruptive technological approach changing wireless communications, radar, and surveillance system architectures dramatically. Practical results were achieved for Digital-RF systems in which wide-band, multi-band radio frequency signals are directly digitized and digital domain is expanded throughout the entire system. Digital-RF systems combine digital and mixed signal integrated circuits based on Rapid Single Flux Quantum (RSFQ) technology, superconductor analog filter circuits, and semiconductor post-processing circuits. The demonstrated cryocooled Digital-RF systems are the world's first and fastest directly digitizing receivers operating with live satellite signals, enabling multi-net data links, and performing signal acquisition from HF to L-band with 30 GHz clock frequencies. In supercomputing, superconductivity leads to the highest energy efficiencies per operation. Superconductor technology based on manipulation and ballistic transfer of magnetic flux quanta provides a superior low-power alternative to CMOS and other charge-transfer based device technologies. The fundamental energy consumption in SFQ circuits defined by flux quanta energy 2 x 10-19 J. Recently, a novel energy-efficient zero-static-power SFQ technology, eSFQ/ERSFQ was invented, which retains all advantages of standard RSFQ circuits: high-speed, dc power, internal memory. The voltage bias regulation, determined by SFQ clock, enables the zero-power at zero-activity regimes, indispensable for sensor and quantum bit readout.

1-Million droplet array with wide-field fluorescence imaging for digital PCR.

PubMed

Hatch, Andrew C; Fisher, Jeffrey S; Tovar, Armando R; Hsieh, Albert T; Lin, Robert; Pentoney, Stephen L; Yang, David L; Lee, Abraham P

2011-11-21

Digital droplet reactors are useful as chemical and biological containers to discretize reagents into picolitre or nanolitre volumes for analysis of single cells, organisms, or molecules. However, most DNA based assays require processing of samples on the order of tens of microlitres and contain as few as one to as many as millions of fragments to be detected. Presented in this work is a droplet microfluidic platform and fluorescence imaging setup designed to better meet the needs of the high-throughput and high-dynamic-range by integrating multiple high-throughput droplet processing schemes on the chip. The design is capable of generating over 1-million, monodisperse, 50 picolitre droplets in 2-7 minutes that then self-assemble into high density 3-dimensional sphere packing configurations in a large viewing chamber for visualization and analysis. This device then undergoes on-chip polymerase chain reaction (PCR) amplification and fluorescence detection to digitally quantify the sample's nucleic acid contents. Wide-field fluorescence images are captured using a low cost 21-megapixel digital camera and macro-lens with an 8-12 cm(2) field-of-view at 1× to 0.85× magnification, respectively. We demonstrate both end-point and real-time imaging ability to perform on-chip quantitative digital PCR analysis of the entire droplet array. Compared to previous work, this highly integrated design yields a 100-fold increase in the number of on-chip digitized reactors with simultaneous fluorescence imaging for digital PCR based assays.

Generation of high-dynamic range image from digital photo

NASA Astrophysics Data System (ADS)

Wang, Ying; Potemin, Igor S.; Zhdanov, Dmitry D.; Wang, Xu-yang; Cheng, Han

2016-10-01

A number of the modern applications such as medical imaging, remote sensing satellites imaging, virtual prototyping etc use the High Dynamic Range Image (HDRI). Generally to obtain HDRI from ordinary digital image the camera is calibrated. The article proposes the camera calibration method based on the clear sky as the standard light source and takes sky luminance from CIE sky model for the corresponding geographical coordinates and time. The article considers base algorithms for getting real luminance values from ordinary digital image and corresponding programmed implementation of the algorithms. Moreover, examples of HDRI reconstructed from ordinary images illustrate the article.

Application of digital control techniques for satellite medium power DC-DC converters

NASA Astrophysics Data System (ADS)

Skup, Konrad R.; Grudzinski, Pawel; Nowosielski, Witold; Orleanski, Piotr; Wawrzaszek, Roman

2010-09-01

The objective of this paper is to present a work concerning a digital control loop system for satellite medium power DC-DC converters that is done in Space Research Centre. The whole control process of a described power converter bases on a high speed digital signal processing. The paper presents a development of a FPGA digital controller for voltage mode stabilization that was implemented using VHDL. The described controllers are a classical digital PID controller and a bang-bang controller. The used converter for testing is a simple model of 5-20 W, 200 kHz buck power converter. A high resolution digital PWM approach is presented. Additionally a simple and effective solution of filtering of an analog-to-digital converter output is presented.

A high capacity data recording device based on a digital audio processor and a video cassette recorder.

PubMed

Bezanilla, F

1985-03-01

A modified digital audio processor, a video cassette recorder, and some simple added circuitry are assembled into a recording device of high capacity. The unit converts two analog channels into digital form at 44-kHz sampling rate and stores the information in digital form in a common video cassette. Bandwidth of each channel is from direct current to approximately 20 kHz and the dynamic range is close to 90 dB. The total storage capacity in a 3-h video cassette is 2 Gbytes. The information can be retrieved in analog or digital form.

A high capacity data recording device based on a digital audio processor and a video cassette recorder.

PubMed Central

Bezanilla, F

1985-01-01

A modified digital audio processor, a video cassette recorder, and some simple added circuitry are assembled into a recording device of high capacity. The unit converts two analog channels into digital form at 44-kHz sampling rate and stores the information in digital form in a common video cassette. Bandwidth of each channel is from direct current to approximately 20 kHz and the dynamic range is close to 90 dB. The total storage capacity in a 3-h video cassette is 2 Gbytes. The information can be retrieved in analog or digital form. PMID:3978213

The 3D Digital Story-telling Media on Batik Learning in Vocational High Schools

NASA Astrophysics Data System (ADS)

Widiaty, I.; Achdiani, Y.; Kuntadi, I.; Mubaroq, S. R.; Zakaria, D.

2018-02-01

The aim of this research is to make 3D digital Story-telling Media on Batik Learning in Vocational High School. The digital story-telling developed in this research is focused on 3D-based story-telling. In contrast to the digital story-telling that has been developed in existing learning, this research is expected to be able to improve understanding of vocational students about the value of local wisdom batik more meaningful and “live”. The process of making 3D digital story-telling media consists of two processes, namely the creation of 3D objects and the creation of 3D object viewer.

Carbon nanotube transistor based high-frequency electronics

NASA Astrophysics Data System (ADS)

Schroter, Michael

At the nanoscale carbon nanotubes (CNTs) have higher carrier mobility and carrier velocity than most incumbent semiconductors. Thus CNT based field-effect transistors (FETs) are being considered as strong candidates for replacing existing MOSFETs in digital applications. In addition, the predicted high intrinsic transit frequency and the more recent finding of ways to achieve highly linear transfer characteristics have inspired investigations on analog high-frequency (HF) applications. High linearity is extremely valuable for an energy efficient usage of the frequency spectrum, particularly in mobile communications. Compared to digital applications, the much more relaxed constraints for CNT placement and lithography combined with already achieved operating frequencies of at least 10 GHz for fabricated devices make an early entry in the low GHz HF market more feasible than in large-scale digital circuits. Such a market entry would be extremely beneficial for funding the development of production CNTFET based process technology. This talk will provide an overview on the present status and feasibility of HF CNTFET technology will be given from an engineering point of view, including device modeling, experimental results, and existing roadblocks. Carbon nanotube transistor based high-frequency electronics.

A New Statistics-Based Online Baseline Restorer for a High Count-Rate Fully Digital System.

PubMed

Li, Hongdi; Wang, Chao; Baghaei, Hossain; Zhang, Yuxuan; Ramirez, Rocio; Liu, Shitao; An, Shaohui; Wong, Wai-Hoi

2010-04-01

The goal of this work is to develop a novel, accurate, real-time digital baseline restorer using online statistical processing for a high count-rate digital system such as positron emission tomography (PET). In high count-rate nuclear instrumentation applications, analog signals are DC-coupled for better performance. However, the detectors, pre-amplifiers and other front-end electronics would cause a signal baseline drift in a DC-coupling system, which will degrade the performance of energy resolution and positioning accuracy. Event pileups normally exist in a high-count rate system and the baseline drift will create errors in the event pileup-correction. Hence, a baseline restorer (BLR) is required in a high count-rate system to remove the DC drift ahead of the pileup correction. Many methods have been reported for BLR from classic analog methods to digital filter solutions. However a single channel BLR with analog method can only work under 500 kcps count-rate, and normally an analog front-end application-specific integrated circuits (ASIC) is required for the application involved hundreds BLR such as a PET camera. We have developed a simple statistics-based online baseline restorer (SOBLR) for a high count-rate fully digital system. In this method, we acquire additional samples, excluding the real gamma pulses, from the existing free-running ADC in the digital system, and perform online statistical processing to generate a baseline value. This baseline value will be subtracted from the digitized waveform to retrieve its original pulse with zero-baseline drift. This method can self-track the baseline without a micro-controller involved. The circuit consists of two digital counter/timers, one comparator, one register and one subtraction unit. Simulation shows a single channel works at 30 Mcps count-rate with pileup condition. 336 baseline restorer circuits have been implemented into 12 field-programmable-gate-arrays (FPGA) for our new fully digital PET system.

Investigation of FPGA-Based Real-Time Adaptive Digital Pulse Shaping for High-Count-Rate Applications

NASA Astrophysics Data System (ADS)

Saxena, Shefali; Hawari, Ayman I.

2017-07-01

Digital signal processing techniques have been widely used in radiation spectrometry to provide improved stability and performance with compact physical size over the traditional analog signal processing. In this paper, field-programmable gate array (FPGA)-based adaptive digital pulse shaping techniques are investigated for real-time signal processing. National Instruments (NI) NI 5761 14-bit, 250-MS/s adaptor module is used for digitizing high-purity germanium (HPGe) detector's preamplifier pulses. Digital pulse processing algorithms are implemented on the NI PXIe-7975R reconfigurable FPGA (Kintex-7) using the LabVIEW FPGA module. Based on the time separation between successive input pulses, the adaptive shaping algorithm selects the optimum shaping parameters (rise time and flattop time of trapezoid-shaping filter) for each incoming signal. A digital Sallen-Key low-pass filter is implemented to enhance signal-to-noise ratio and reduce baseline drifting in trapezoid shaping. A recursive trapezoid-shaping filter algorithm is employed for pole-zero compensation of exponentially decayed (with two-decay constants) preamplifier pulses of an HPGe detector. It allows extraction of pulse height information at the beginning of each pulse, thereby reducing the pulse pileup and increasing throughput. The algorithms for RC-CR2 timing filter, baseline restoration, pile-up rejection, and pulse height determination are digitally implemented for radiation spectroscopy. Traditionally, at high-count-rate conditions, a shorter shaping time is preferred to achieve high throughput, which deteriorates energy resolution. In this paper, experimental results are presented for varying count-rate and pulse shaping conditions. Using adaptive shaping, increased throughput is accepted while preserving the energy resolution observed using the longer shaping times.

VLSI-based video event triggering for image data compression

NASA Astrophysics Data System (ADS)

Williams, Glenn L.

1994-02-01

Long-duration, on-orbit microgravity experiments require a combination of high resolution and high frame rate video data acquisition. The digitized high-rate video stream presents a difficult data storage problem. Data produced at rates of several hundred million bytes per second may require a total mission video data storage requirement exceeding one terabyte. A NASA-designed, VLSI-based, highly parallel digital state machine generates a digital trigger signal at the onset of a video event. High capacity random access memory storage coupled with newly available fuzzy logic devices permits the monitoring of a video image stream for long term (DC-like) or short term (AC-like) changes caused by spatial translation, dilation, appearance, disappearance, or color change in a video object. Pre-trigger and post-trigger storage techniques are then adaptable to archiving only the significant video images.

VLSI-based Video Event Triggering for Image Data Compression

NASA Technical Reports Server (NTRS)

Williams, Glenn L.

1994-01-01

Long-duration, on-orbit microgravity experiments require a combination of high resolution and high frame rate video data acquisition. The digitized high-rate video stream presents a difficult data storage problem. Data produced at rates of several hundred million bytes per second may require a total mission video data storage requirement exceeding one terabyte. A NASA-designed, VLSI-based, highly parallel digital state machine generates a digital trigger signal at the onset of a video event. High capacity random access memory storage coupled with newly available fuzzy logic devices permits the monitoring of a video image stream for long term (DC-like) or short term (AC-like) changes caused by spatial translation, dilation, appearance, disappearance, or color change in a video object. Pre-trigger and post-trigger storage techniques are then adaptable to archiving only the significant video images.

Representation and matching of knowledge to design digital systems

NASA Technical Reports Server (NTRS)

Jones, J. U.; Shiva, S. G.

1988-01-01

A knowledge-based expert system is described that provides an approach to solve a problem requiring an expert with considerable domain expertise and facts about available digital hardware building blocks. To design digital hardware systems from their high level VHDL (Very High Speed Integrated Circuit Hardware Description Language) representation to their finished form, a special data representation is required. This data representation as well as the functioning of the overall system is described.

Validation of a Plasma-Based Comprehensive Cancer Genotyping Assay Utilizing Orthogonal Tissue- and Plasma-Based Methodologies.

PubMed

Odegaard, Justin I; Vincent, John J; Mortimer, Stefanie; Vowles, James V; Ulrich, Bryan C; Banks, Kimberly C; Fairclough, Stephen R; Zill, Oliver A; Sikora, Marcin; Mokhtari, Reza; Abdueva, Diana; Nagy, Rebecca J; Lee, Christine E; Kiedrowski, Lesli A; Paweletz, Cloud P; Eltoukhy, Helmy; Lanman, Richard B; Chudova, Darya I; Talasaz, AmirAli

2018-04-24

Purpose: To analytically and clinically validate a circulating cell-free tumor DNA sequencing test for comprehensive tumor genotyping and demonstrate its clinical feasibility. Experimental Design: Analytic validation was conducted according to established principles and guidelines. Blood-to-blood clinical validation comprised blinded external comparison with clinical droplet digital PCR across 222 consecutive biomarker-positive clinical samples. Blood-to-tissue clinical validation comprised comparison of digital sequencing calls to those documented in the medical record of 543 consecutive lung cancer patients. Clinical experience was reported from 10,593 consecutive clinical samples. Results: Digital sequencing technology enabled variant detection down to 0.02% to 0.04% allelic fraction/2.12 copies with ≤0.3%/2.24-2.76 copies 95% limits of detection while maintaining high specificity [prevalence-adjusted positive predictive values (PPV) >98%]. Clinical validation using orthogonal plasma- and tissue-based clinical genotyping across >750 patients demonstrated high accuracy and specificity [positive percent agreement (PPAs) and negative percent agreement (NPAs) >99% and PPVs 92%-100%]. Clinical use in 10,593 advanced adult solid tumor patients demonstrated high feasibility (>99.6% technical success rate) and clinical sensitivity (85.9%), with high potential actionability (16.7% with FDA-approved on-label treatment options; 72.0% with treatment or trial recommendations), particularly in non-small cell lung cancer, where 34.5% of patient samples comprised a directly targetable standard-of-care biomarker. Conclusions: High concordance with orthogonal clinical plasma- and tissue-based genotyping methods supports the clinical accuracy of digital sequencing across all four types of targetable genomic alterations. Digital sequencing's clinical applicability is further supported by high rates of technical success and biomarker target discovery. Clin Cancer Res; 1-11. ©2018 AACR. ©2018 American Association for Cancer Research.

Fusion of lens-free microscopy and mobile-phone microscopy images for high-color-accuracy and high-resolution pathology imaging

NASA Astrophysics Data System (ADS)

Zhang, Yibo; Wu, Yichen; Zhang, Yun; Ozcan, Aydogan

2017-03-01

Digital pathology and telepathology require imaging tools with high-throughput, high-resolution and accurate color reproduction. Lens-free on-chip microscopy based on digital in-line holography is a promising technique towards these needs, as it offers a wide field of view (FOV >20 mm2) and high resolution with a compact, low-cost and portable setup. Color imaging has been previously demonstrated by combining reconstructed images at three discrete wavelengths in the red, green and blue parts of the visible spectrum, i.e., the RGB combination method. However, this RGB combination method is subject to color distortions. To improve the color performance of lens-free microscopy for pathology imaging, here we present a wavelet-based color fusion imaging framework, termed "digital color fusion microscopy" (DCFM), which digitally fuses together a grayscale lens-free microscope image taken at a single wavelength and a low-resolution and low-magnification color-calibrated image taken by a lens-based microscope, which can simply be a mobile phone based cost-effective microscope. We show that the imaging results of an H&E stained breast cancer tissue slide with the DCFM technique come very close to a color-calibrated microscope using a 40x objective lens with 0.75 NA. Quantitative comparison showed 2-fold reduction in the mean color distance using the DCFM method compared to the RGB combination method, while also preserving the high-resolution features of the lens-free microscope. Due to the cost-effective and field-portable nature of both lens-free and mobile-phone microscopy techniques, their combination through the DCFM framework could be useful for digital pathology and telepathology applications, in low-resource and point-of-care settings.

Timing performance comparison of digital methods in positron emission tomography

NASA Astrophysics Data System (ADS)

Aykac, Mehmet; Hong, Inki; Cho, Sanghee

2010-11-01

Accurate timing information is essential in positron emission tomography (PET). Recent improvements in high speed electronics made digital methods more attractive to find alternative solutions to create a time mark for an event. Two new digital methods (mean PMT pulse model, MPPM, and median filtered zero crossing method, MFZCM) were introduced in this work and compared to traditional methods such as digital leading edge (LE) and digital constant fraction discrimination (CFD). In addition, the performances of all four digital methods were compared to analog based LE and CFD. The time resolution values for MPPM and MFZCM were measured below 300 ps at 1.6 GS/s and above that was similar to the analog based coincidence timing results. In addition, the two digital methods were insensitive to the changes in threshold setting that might give some improvement in system dead time.

CMOS based capacitance to digital converter circuit for MEMS sensor

NASA Astrophysics Data System (ADS)

Rotake, D. R.; Darji, A. D.

2018-02-01

Most of the MEMS cantilever based system required costly instruments for characterization, processing and also has large experimental setups which led to non-portable device. So there is a need of low cost, highly sensitive, high speed and portable digital system. The proposed Capacitance to Digital Converter (CDC) interfacing circuit converts capacitance to digital domain which can be easily processed. Recent demand microcantilever deflection is part per trillion ranges which change the capacitance in 1-10 femto farad (fF) range. The entire CDC circuit is designed using CMOS 250nm technology. Design of CDC circuit consists of a D-latch and two oscillators, namely Sensor controlled oscillator (SCO) and digitally controlled oscillator (DCO). The D-latch is designed using transmission gate based MUX for power optimization. A CDC design of 7-stage, 9-stage and 11-stage tested for 1-18 fF and simulated using mentor graphics Eldo tool with parasitic. Since the proposed design does not use resistance component, the total power dissipation is reduced to 2.3621 mW for CDC designed using 9-stage SCO and DCO.

Highly Stretchable and UV Curable Elastomers for Digital Light Processing Based 3D Printing.

PubMed

Patel, Dinesh K; Sakhaei, Amir Hosein; Layani, Michael; Zhang, Biao; Ge, Qi; Magdassi, Shlomo

2017-04-01

Stretchable UV-curable (SUV) elastomers can be stretched by up to 1100% and are suitable for digital-light-processing (DLP)-based 3D-printing technology. DLP printing of these SUV elastomers enables the direct creation of highly deformable complex 3D hollow structures such as balloons, soft actuators, grippers, and buckyball electronical switches. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Teaching and Learning Physics in a 1:1 Laptop School

NASA Astrophysics Data System (ADS)

Zucker, Andrew A.; Hug, Sarah T.

2008-12-01

1:1 laptop programs, in which every student is provided with a personal computer to use during the school year, permit increased and routine use of powerful, user-friendly computer-based tools. Growing numbers of 1:1 programs are reshaping the roles of teachers and learners in science classrooms. At the Denver School of Science and Technology, a public charter high school where a large percentage of students come from low-income families, 1:1 laptops are used often by teachers and students. This article describes the school's use of laptops, the Internet, and related digital tools, especially for teaching and learning physics. The data are from teacher and student surveys, interviews, classroom observations, and document analyses. Physics students and teachers use an interactive digital textbook; Internet-based simulations (some developed by a Nobel Prize winner); word processors; digital drop boxes; email; formative electronic assessments; computer-based and stand-alone graphing calculators; probes and associated software; and digital video cameras to explore hypotheses, collaborate, engage in scientific inquiry, and to identify strengths and weaknesses of students' understanding of physics. Technology provides students at DSST with high-quality tools to explore scientific concepts and the experiences of teachers and students illustrate effective uses of digital technology for high school physics.

Forest Stand Canopy Structure Attribute Estimation from High Resolution Digital Airborne Imagery

Treesearch

Demetrios Gatziolis

2006-01-01

A study of forest stand canopy variable assessment using digital, airborne, multispectral imagery is presented. Variable estimation involves stem density, canopy closure, and mean crown diameter, and it is based on quantification of spatial autocorrelation among pixel digital numbers (DN) using variogram analysis and an alternative, non-parametric approach known as...

Web-based virtual microscopy at the RWTH Aachen University: didactic concept, methods and analysis of acceptance by the students.

PubMed

Merk, Magdalene; Knuechel, Ruth; Perez-Bouza, Alberto

2010-12-20

Fundamental knowledge of microscopic anatomy and pathology has always been an essential part in medical education. The traditional didactic concept comprises theoretical and practical lessons using a light microscope and glass slides. High-speed Internet connections and technical improvement in whole-slide digital microscopy (commonly termed "virtual microscopy") provide a new and attractive approach for both teachers and students. High picture quality and unlimited temporal and spatial availability of histology samples from different fields are key advantages of web-based digital microscopy. In this report we discuss the technical requirements, system efficiency, optical resolution and didactic concept. Furthermore, we present a review of the experience gained in the course of one year based on an analysis of student acceptance. Three groups with a total of 192 students between the 3rd and 5th year of medical studies attending the practical courses of general and advanced histopathology had access to both glass-mounted and digitalized slides. Prior to exams, students were asked to answer an anonymous questionnaire. The results of the study reflect the high acceptance and intensive use of the web-based digital histology by students, thus encouraging the development of further Web-based learning strategies for the teaching of histology and pathology. 2010 Elsevier GmbH. All rights reserved.

A home-built digital optical MRI console using high-speed serial links.

PubMed

Tang, Weinan; Wang, Weimin; Liu, Wentao; Ma, Yajun; Tang, Xin; Xiao, Liang; Gao, Jia-Hong

2015-08-01

To develop a high performance, cost-effective digital optical console for scalable multichannel MRI. The console system was implemented with flexibility and efficiency based on a modular architecture with distributed pulse sequencers. High-speed serial links were optimally utilized to interconnect the system, providing fast digital communication with a multi-gigabit data rate. The conventional analog radio frequency (RF) chain was replaced with a digital RF manipulation. The acquisition electronics were designed in close proximity to RF coils and preamplifiers, using a digital optical link to transmit the MR signal. A prototype of the console was constructed with a broad frequency range from direct current to 100 MHz. A temporal resolution of 1 μs was achieved for both the RF and gradient operations. The MR signal was digitized in the scanner room with an overall dynamic range between 16 and 24 bits and was transmitted to a master controller over a duplex optic fiber with a high data rate of 3.125 gigabits per second. High-quality phantom and human images were obtained using the prototype on both 0.36T and 1.5T clinical MRI scanners. A homemade digital optical MRI console with high-speed serial interconnection has been developed to better serve imaging research and clinical applications. © 2014 Wiley Periodicals, Inc.

Creating an EPICS Based Test Stand Development System for a BPM Digitizer of the Linac Coherent Light Source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-06-22

The Linac Coherent Light Source (LCLS) is required to deliver a high quality electron beam for producing coherent X-rays. As a result, high resolution beam position monitoring is required. The Beam Position Monitor (BPM) digitizer acquires analog signals from the beam line and digitizes them to obtain beam position data. Although Matlab is currently being used to test the BPM digitizer?s functions and capability, the Controls Department at SLAC prefers to use Experimental Physics and Industrial Control Systems (EPICS). This paper discusses the transition of providing similar as well as enhanced functionalities, than those offered by Matlab, to test themore » digitizer. Altogether, the improved test stand development system can perform mathematical and statistical calculations with the waveform signals acquired from the digitizer and compute the fast Fourier transform (FFT) of the signals. Finally, logging of meaningful data into files has been added.« less

Frequency Based Design Partitioning to Achieve Higher Throughput in Digital Cross Correlator for Aperture Synthesis Passive MMW Imager.

PubMed

Asif, Muhammad; Guo, Xiangzhou; Zhang, Jing; Miao, Jungang

2018-04-17

Digital cross-correlation is central to many applications including but not limited to Digital Image Processing, Satellite Navigation and Remote Sensing. With recent advancements in digital technology, the computational demands of such applications have increased enormously. In this paper we are presenting a high throughput digital cross correlator, capable of processing 1-bit digitized stream, at the rate of up to 2 GHz, simultaneously on 64 channels i.e., approximately 4 Trillion correlation and accumulation operations per second. In order to achieve higher throughput, we have focused on frequency based partitioning of our design and tried to minimize and localize high frequency operations. This correlator is designed for a Passive Millimeter Wave Imager intended for the detection of contraband items concealed on human body. The goals are to increase the system bandwidth, achieve video rate imaging, improve sensitivity and reduce the size. Design methodology is detailed in subsequent sections, elaborating the techniques enabling high throughput. The design is verified for Xilinx Kintex UltraScale device in simulation and the implementation results are given in terms of device utilization and power consumption estimates. Our results show considerable improvements in throughput as compared to our baseline design, while the correlator successfully meets the functional requirements.

Comparing the Reading Performance of High-Achieving Adolescents: Computer-Based Testing versus Paper/Pencil

ERIC Educational Resources Information Center

Eno, Linda Peet

2011-01-01

Literacy is moving into the digital context. Many of the literacy tasks associated with higher education, the workplace, and civic life now take place in the digital world. Literacy in high school, however, languishes in the text world. This study compared the text literacy of a group of high-achieving 10th-grade students, to their digital…

Establishment of a Digital Knowledge Conversion Architecture Design Learning with High User Acceptance

ERIC Educational Resources Information Center

Wu, Yun-Wu; Weng, Apollo; Weng, Kuo-Hua

2017-01-01

The purpose of this study is to design a knowledge conversion and management digital learning system for architecture design learning, helping students to share, extract, use and create their design knowledge through web-based interactive activities based on socialization, internalization, combination and externalization process in addition to…

Digital super-resolution holographic data storage based on Hermitian symmetry for achieving high areal density.

PubMed

Nobukawa, Teruyoshi; Nomura, Takanori

2017-01-23

Digital super-resolution holographic data storage based on Hermitian symmetry is proposed to store digital data in a tiny area of a medium. In general, reducing a recording area with an aperture leads to the improvement in the storage capacity of holographic data storage. Conventional holographic data storage systems however have a limitation in reducing a recording area. This limitation is called a Nyquist size. Unlike the conventional systems, our proposed system can overcome the limitation with the help of a digital holographic technique and digital signal processing. Experimental result shows that the proposed system can record and retrieve a hologram in a smaller area than the Nyquist size on the basis of Hermitian symmetry.

Optical communication in free space

NASA Technical Reports Server (NTRS)

Plotkin, H. H.; Mcavoy, N.; Fitzmaurice, M. W.

1974-01-01

Two classes of laser communication systems for handling very high data rates across inter-satellite distances are considered that provide for high antenna gains, wide modulation bandwidths, and optical receiver sensitivities. System design considerations are based upon the carbon dioxide laser modulation to accommodate digital or analog information, and the neodymium doped YAG laser pulse for digital modulation.

Design Principles for "Thriving in Our Digital World": A High School Computer Science Course

ERIC Educational Resources Information Center

Veletsianos, George; Beth, Bradley; Lin, Calvin; Russell, Gregory

2016-01-01

"Thriving in Our Digital World" is a technology-enhanced dual enrollment course introducing high school students to computer science through project- and problem-based learning. This article describes the evolution of the course and five lessons learned during the design, development, implementation, and iteration of the course from its…

Mixed Linear/Square-Root Encoded Single Slope Ramp Provides a Fast, Low Noise Analog to Digital Converter with Very High Linearity for Focal Plane Arrays

NASA Technical Reports Server (NTRS)

Wrigley, Christopher James (Inventor); Hancock, Bruce R. (Inventor); Cunningham, Thomas J. (Inventor); Newton, Kenneth W. (Inventor)

2014-01-01

An analog-to-digital converter (ADC) converts pixel voltages from a CMOS image into a digital output. A voltage ramp generator generates a voltage ramp that has a linear first portion and a non-linear second portion. A digital output generator generates a digital output based on the voltage ramp, the pixel voltages, and comparator output from an array of comparators that compare the voltage ramp to the pixel voltages. A return lookup table linearizes the digital output values.

Digital Badges for STEM Learning in Secondary Contexts: A Mixed Methods Study

NASA Astrophysics Data System (ADS)

Elkordy, Angela

The deficit in STEM skills is a matter of concern for national economies and a major focus for educational policy makers. The development of Information and Communications Technologies (ICT) has resulted in a rapidly changing workforce of global scale. In addition, ICT have fostered the growth of digital and mobile technologies which have been the learning context, formal and informal, for a generation of youth. The purpose of this study was to design an intervention based upon a competency-based, digitally-mediated, learning intervention: digital badges for learning STEM habits of mind and practices. Designed purposefully, digital badge learning trajectories and criteria can be flexible tools for scaffolding, measuring, and communicating the acquisition of knowledge, skills, or competencies. One of the most often discussed attributes of digital badges, is the ability of badges to motivate learners. However, the research base to support this claim is in its infancy; there is little empirical evidence. A skills-based digital badge intervention was designed to demonstrate mastery learning in key, age-appropriate, STEM competencies aligned with Next Generation Science Standards (NGSS) and other educational standards. A mixed methods approach was used to study the impact of a digital badge intervention in the sample middle and high school population. Among the findings were statistically significant measures which substantiate that in this student population, the digital badges increased perceived competence and motivated learners to persist at task.

A defocus-information-free autostereoscopic three-dimensional (3D) digital reconstruction method using direct extraction of disparity information (DEDI)

NASA Astrophysics Data System (ADS)

Li, Da; Cheung, Chifai; Zhao, Xing; Ren, Mingjun; Zhang, Juan; Zhou, Liqiu

2016-10-01

Autostereoscopy based three-dimensional (3D) digital reconstruction has been widely applied in the field of medical science, entertainment, design, industrial manufacture, precision measurement and many other areas. The 3D digital model of the target can be reconstructed based on the series of two-dimensional (2D) information acquired by the autostereoscopic system, which consists multiple lens and can provide information of the target from multiple angles. This paper presents a generalized and precise autostereoscopic three-dimensional (3D) digital reconstruction method based on Direct Extraction of Disparity Information (DEDI) which can be used to any transform autostereoscopic systems and provides accurate 3D reconstruction results through error elimination process based on statistical analysis. The feasibility of DEDI method has been successfully verified through a series of optical 3D digital reconstruction experiments on different autostereoscopic systems which is highly efficient to perform the direct full 3D digital model construction based on tomography-like operation upon every depth plane with the exclusion of the defocused information. With the absolute focused information processed by DEDI method, the 3D digital model of the target can be directly and precisely formed along the axial direction with the depth information.

Digital holographic image fusion for a larger size object using compressive sensing

NASA Astrophysics Data System (ADS)

Tian, Qiuhong; Yan, Liping; Chen, Benyong; Yao, Jiabao; Zhang, Shihua

2017-05-01

Digital holographic imaging fusion for a larger size object using compressive sensing is proposed. In this method, the high frequency component of the digital hologram under discrete wavelet transform is represented sparsely by using compressive sensing so that the data redundancy of digital holographic recording can be resolved validly, the low frequency component is retained totally to ensure the image quality, and multiple reconstructed images with different clear parts corresponding to a laser spot size are fused to realize the high quality reconstructed image of a larger size object. In addition, a filter combing high-pass and low-pass filters is designed to remove the zero-order term from a digital hologram effectively. The digital holographic experimental setup based on off-axis Fresnel digital holography was constructed. The feasible and comparative experiments were carried out. The fused image was evaluated by using the Tamura texture features. The experimental results demonstrated that the proposed method can improve the processing efficiency and visual characteristics of the fused image and enlarge the size of the measured object effectively.

Epistemic agency in an environmental sciences watershed investigation fostered by digital photography

NASA Astrophysics Data System (ADS)

Zimmerman, Heather Toomey; Weible, Jennifer L.

2018-05-01

This collective case study investigates the role of digital photography to support high school students' engagement in science inquiry practices during a three-week environmental sciences unit. The study's theoretical framework brings together research from digital photography, participation in environmental science practices, and epistemic agency. Data analysed include field notes and video transcripts from two groups of learners (n = 19) that focus on how high school students used digital photography during their participation in two distinct environmental monitoring practices: stream mapping and macroinvertebrate identification. Our study resulted in two findings related to the role of digital photography where students developed knowledge as they engaged in environmental monitoring inquiry practices. First, we found that digital photography was integral to the youths' epistemic agency (defined as their confidence that they could build knowledge related to science in their community) as they engaged in data collection, documenting environmental monitoring procedures, and sharing data in the classroom. Based this finding, an implication of our work is a refined view of the role of digital photography in environmental sciences education where the use of photography enhances epistemic agency in inquiry-based activities. Second, we found that the youths innovated a use of digital photography to foster a recognition that they were capable and competent in scientific procedures during a streamside study. Based on this finding, we offer a theoretical implication that expands the construct of epistemic agency; we posit that epistemic agency includes a subcomponent where the students purposefully formulate an external recognition as producers of scientific knowledge.

FERMI: a digital Front End and Readout MIcrosystem for high resolution calorimetry

NASA Astrophysics Data System (ADS)

Alexanian, H.; Appelquist, G.; Bailly, P.; Benetta, R.; Berglund, S.; Bezamat, J.; Blouzon, F.; Bohm, C.; Breveglieri, L.; Brigati, S.; Cattaneo, P. W.; Dadda, L.; David, J.; Engström, M.; Genat, J. F.; Givoletti, M.; Goggi, V. G.; Gong, S.; Grieco, G. M.; Hansen, M.; Hentzell, H.; Holmberg, T.; Höglund, I.; Inkinen, S. J.; Kerek, A.; Landi, C.; Ledortz, O.; Lippi, M.; Lofstedt, B.; Lund-Jensen, B.; Maloberti, F.; Mutz, S.; Nayman, P.; Piuri, V.; Polesello, G.; Sami, M.; Savoy-Navarro, A.; Schwemling, P.; Stefanelli, R.; Sundblad, R.; Svensson, C.; Torelli, G.; Vanuxem, J. P.; Yamdagni, N.; Yuan, J.; Ödmark, A.; Fermi Collaboration

1995-02-01

We present a digital solution for the front-end electronics of high resolution calorimeters at future colliders. It is based on analogue signal compression, high speed {A}/{D} converters, a fully programmable pipeline and a digital signal processing (DSP) chain with local intelligence and system supervision. This digital solution is aimed at providing maximal front-end processing power by performing waveform analysis using DSP methods. For the system integration of the multichannel device a multi-chip, silicon-on-silicon multi-chip module (MCM) has been adopted. This solution allows a high level of integration of complex analogue and digital functions, with excellent flexibility in mixing technologies for the different functional blocks. This type of multichip integration provides a high degree of reliability and programmability at both the function and the system level, with the additional possibility of customising the microsystem to detector-specific requirements. For enhanced reliability in high radiation environments, fault tolerance strategies, i.e. redundancy, reconfigurability, majority voting and coding for error detection and correction, are integrated into the design.

Carbon nanotube transistor based high-frequency electronics

NASA Astrophysics Data System (ADS)

Schroter, Michael

At the nanoscale carbon nanotubes (CNTs) have higher carrier mobility and carrier velocity than most incumbent semiconductors. Thus CNT based field-effect transistors (FETs) are being considered as strong candidates for replacing existing MOSFETs in digital applications. In addition, the predicted high intrinsic transit frequency and the more recent finding of ways to achieve highly linear transfer characteristics have inspired investigations on analog high-frequency (HF) applications. High linearity is extremely valuable for an energy efficient usage of the frequency spectrum, particularly in mobile communications. Compared to digital applications, the much more relaxed constraints for CNT placement and lithography combined with already achieved operating frequencies of at least 10 GHz for fabricated devices make an early entry in the low GHz HF market more feasible than in large-scale digital circuits. Such a market entry would be extremely beneficial for funding the development of production CNTFET based process technology. This talk will provide an overview on the present status and feasibility of HF CNTFET technology will be given from an engineering point of view, including device modeling, experimental results, and existing roadblocks.

High-speed technique based on a parallel projection correlation procedure for digital image correlation

NASA Astrophysics Data System (ADS)

Zaripov, D. I.; Renfu, Li

2018-05-01

The implementation of high-efficiency digital image correlation methods based on a zero-normalized cross-correlation (ZNCC) procedure for high-speed, time-resolved measurements using a high-resolution digital camera is associated with big data processing and is often time consuming. In order to speed-up ZNCC computation, a high-speed technique based on a parallel projection correlation procedure is proposed. The proposed technique involves the use of interrogation window projections instead of its two-dimensional field of luminous intensity. This simplification allows acceleration of ZNCC computation up to 28.8 times compared to ZNCC calculated directly, depending on the size of interrogation window and region of interest. The results of three synthetic test cases, such as a one-dimensional uniform flow, a linear shear flow and a turbulent boundary-layer flow, are discussed in terms of accuracy. In the latter case, the proposed technique is implemented together with an iterative window-deformation technique. On the basis of the results of the present work, the proposed technique is recommended to be used for initial velocity field calculation, with further correction using more accurate techniques.

Silicon photonics devices for metro applications

NASA Astrophysics Data System (ADS)

Fukuda, H.; Kikuchi, K.; Jizodo, M.; Kawamura, Y.; Takeda, K.; Honda, K.

2017-01-01

Digital coherent technology is considered an attractive way of realizing both high-speed metro links and long distance transmissions. In metro areas, there is a strong demand for a smaller, faster transceiver module. This demand is mainly driven by the rapidly increasing data center interconnection traffic, where transmission capacity per faceplane is a key feature. Therefore, optical integration technology is desired. Since compensation in digital coherent technology is performed in the electrical or digital domain, users can deal with those optics performances that are not compensated for digitally. This means using a new material that cannot provide perfect characteristics but that is suitable for miniaturization and integration is possible. Silicon photonics (SiPh) is considered an attractive technology that would enable the significant miniaturization of optical circuits and be capable of optical integration with high manufacturability. While SiPh-based devices have begun to be deployed for very short or short reach links on the basis of direct detection technology, their digital coherent applications have recently been investigated in view of their integration capability. This paper describes recent progress on SiPh-based integrated optical devices for high-speed digital coherent transceivers targeting metro links. An optical modulator and receiver with related circuits have been integrated into a single SiPh chip. TEC-free operation under non-hermetic conditions and the direct attachment of optical fibers have both been realized. Very thin and small packaging with sufficient performance has been demonstrated by using the SiPh chip co-packaged with high-speed ICs.

High Speed Digital Camera Technology Review

NASA Technical Reports Server (NTRS)

Clements, Sandra D.

2009-01-01

A High Speed Digital Camera Technology Review (HSD Review) is being conducted to evaluate the state-of-the-shelf in this rapidly progressing industry. Five HSD cameras supplied by four camera manufacturers participated in a Field Test during the Space Shuttle Discovery STS-128 launch. Each camera was also subjected to Bench Tests in the ASRC Imaging Development Laboratory. Evaluation of the data from the Field and Bench Tests is underway. Representatives from the imaging communities at NASA / KSC and the Optical Systems Group are participating as reviewers. A High Speed Digital Video Camera Draft Specification was updated to address Shuttle engineering imagery requirements based on findings from this HSD Review. This draft specification will serve as the template for a High Speed Digital Video Camera Specification to be developed for the wider OSG imaging community under OSG Task OS-33.

Theoretical design and analysis of multivolume digital assays with wide dynamic range validated experimentally with microfluidic digital PCR.

PubMed

Kreutz, Jason E; Munson, Todd; Huynh, Toan; Shen, Feng; Du, Wenbin; Ismagilov, Rustem F

2011-11-01

This paper presents a protocol using theoretical methods and free software to design and analyze multivolume digital PCR (MV digital PCR) devices; the theory and software are also applicable to design and analysis of dilution series in digital PCR. MV digital PCR minimizes the total number of wells required for "digital" (single molecule) measurements while maintaining high dynamic range and high resolution. In some examples, multivolume designs with fewer than 200 total wells are predicted to provide dynamic range with 5-fold resolution similar to that of single-volume designs requiring 12,000 wells. Mathematical techniques were utilized and expanded to maximize the information obtained from each experiment and to quantify performance of devices and were experimentally validated using the SlipChip platform. MV digital PCR was demonstrated to perform reliably, and results from wells of different volumes agreed with one another. No artifacts due to different surface-to-volume ratios were observed, and single molecule amplification in volumes ranging from 1 to 125 nL was self-consistent. The device presented here was designed to meet the testing requirements for measuring clinically relevant levels of HIV viral load at the point-of-care (in plasma, <500 molecules/mL to >1,000,000 molecules/mL), and the predicted resolution and dynamic range was experimentally validated using a control sequence of DNA. This approach simplifies digital PCR experiments, saves space, and thus enables multiplexing using separate areas for each sample on one chip, and facilitates the development of new high-performance diagnostic tools for resource-limited applications. The theory and software presented here are general and are applicable to designing and analyzing other digital analytical platforms including digital immunoassays and digital bacterial analysis. It is not limited to SlipChip and could also be useful for the design of systems on platforms including valve-based and droplet-based platforms. In a separate publication by Shen et al. (J. Am. Chem. Soc., 2011, DOI: 10.1021/ja2060116), this approach is used to design and test digital RT-PCR devices for quantifying RNA.

Graphical approach for multiple values logic minimization

NASA Astrophysics Data System (ADS)

Awwal, Abdul Ahad S.; Iftekharuddin, Khan M.

1999-03-01

Multiple valued logic (MVL) is sought for designing high complexity, highly compact, parallel digital circuits. However, the practical realization of an MVL-based system is dependent on optimization of cost, which directly affects the optical setup. We propose a minimization technique for MVL logic optimization based on graphical visualization, such as a Karnaugh map. The proposed method is utilized to solve signed-digit binary and trinary logic minimization problems. The usefulness of the minimization technique is demonstrated for the optical implementation of MVL circuits.

ECL gate array with integrated PLL-based clock recovery and synthesis for high-speed data and telecom applications

NASA Astrophysics Data System (ADS)

Rosky, David S.; Coy, Bruce H.; Friedmann, Marc D.

1992-03-01

A 2500 gate mixed signal gate array has been developed that integrates custom PLL-based clock recovery and clock synthesis functions with 2500 gates of configurable logic cells to provide a single chip solution for 200 - 1244 MHz fiber based digital interface applications. By customizing the digital logic cells, any of the popular telecom and datacom standards may be implemented.

The Navy’s Application of Ocean Forecasting to Decision Support

DTIC Science & Technology

2014-09-01

Prediction Center (OPC) website for graphics or the National Operational Model Archive and Distribution System ( NOMADS ) for data files. Regional...inputs: » GLOBE = Global Land One-km Base Elevation » WVS = World Vector Shoreline » DBDB2 = Digital Bathymetry Data Base 2 minute resolution » DBDBV... Digital Bathymetry Data Base variable resolution Oceanography | Vol. 27, No.3130 Very High-Resolution Coastal Circulation Models Nearshore

Programmable pulse generator based on programmable logic and direct digital synthesis.

PubMed

Suchenek, M; Starecki, T

2012-12-01

The paper presents a new approach of pulse generation which results in both wide range tunability and high accuracy of the output pulses. The concept is based on the use of programmable logic and direct digital synthesis. The programmable logic works as a set of programmable counters, while direct digital synthesis (DDS) as the clock source. Use of DDS as the clock source results in stability of the output pulses comparable to the stability of crystal oscillators and quasi-continuous tuning of the output frequency.

Examining unusual digit span performance in a population of postsecondary students assessed for academic difficulties.

PubMed

Harrison, Allyson G; Rosenblum, Yoni; Currie, Shannon

2010-09-01

Methods of identifying poor test-related motivation using the Wechsler Adult Intelligence Scale Digit Span subtest are based on identification of performance patterns that are implausible if the test taker is investing full effort. No studies to date, however, have examined the specificity of such measures, particularly when evaluating persons with either known or suspected learning or attention disorders. This study investigated performance of academically challenged students on three measures embedded in the Wechsler Adult Intelligence Scale-III, namely, low Digit Span, high Vocabulary-Digit span (Voc-DS), and low Reliable Digit Span scores. Evaluating subjects believed to be investing full effort in testing, it was found that both Digit Span and Reliable Digit Span had high specificity, although both showed relatively lower sensitivity. In contrast, VOC-DS was especially weak in both sensitivity and specificity, with an apparent false positive rate of 28%. Use of VOC-DS is therefore not appropriate for those with a history of learning or attention problems.

Development of a Digital Microarray with Interferometric Reflectance Imaging

NASA Astrophysics Data System (ADS)

Sevenler, Derin

This dissertation describes a new type of molecular assay for nucleic acids and proteins. We call this technique a digital microarray since it is conceptually similar to conventional fluorescence microarrays, yet it performs enumerative ('digital') counting of the number captured molecules. Digital microarrays are approximately 10,000-fold more sensitive than fluorescence microarrays, yet maintain all of the strengths of the platform including low cost and high multiplexing (i.e., many different tests on the same sample simultaneously). Digital microarrays use gold nanorods to label the captured target molecules. Each gold nanorod on the array is individually detected based on its light scattering, with an interferometric microscopy technique called SP-IRIS. Our optimized high-throughput version of SP-IRIS is able to scan a typical array of 500 spots in less than 10 minutes. Digital DNA microarrays may have utility in applications where sequencing is prohibitively expensive or slow. As an example, we describe a digital microarray assay for gene expression markers of bacterial drug resistance.

Design and clinical evaluation of a high-capacity digital image archival library and high-speed network for the replacement of cinefilm in the cardiac angiography environment

NASA Astrophysics Data System (ADS)

Cusma, Jack T.; Spero, Laurence A.; Groshong, Bennett R.; Cho, Teddy; Bashore, Thomas M.

1993-09-01

An economical and practical digital solution for the replacement of 35 mm cine film as the archive media in the cardiac x-ray imaging environment has remained lacking to date due to the demanding requirements of high capacity, high acquisition rate, high transfer rate, and a need for application in a distributed environment. A clinical digital image library and network based on the D2 digital video format has been installed in the Duke University Cardiac Catheterization Laboratory. The system architecture includes a central image library with digital video recorders and robotic tape retrieval, three acquisition stations, and remote review stations connected via a serial image network. The library has a capacity for over 20,000 Gigabytes of uncompressed image data, equivalent to records for approximately 20,000 patients. Image acquisition in the clinical laboratories is via a real-time digital interface between the digital angiography system and a local digital recorder. Images are transferred to the library over the serial network at a rate of 14.3 Mbytes/sec and permanently stored for later review. The image library and network are currently undergoing a clinical comparison with cine film for visual and quantitative assessment of coronary artery disease. At the conclusion of the evaluation, the configuration will be expanded to include four additional catheterization laboratories and remote review stations throughout the hospital.

Latency study of the High Performance Time to Digital Converter for the ATLAS Muon Spectrometer trigger upgrade

NASA Astrophysics Data System (ADS)

Meng, X. T.; Levin, D. S.; Chapman, J. W.; Li, D. C.; Yao, Z. E.; Zhou, B.

2017-02-01

The High Performance Time to Digital Converter (HPTDC), a multi-channel ASIC designed by the CERN Microelectronics group, has been proposed for the digitization of the thin-Resistive Plate Chambers (tRPC) in the ATLAS Muon Spectrometer Phase-1 upgrade project. These chambers, to be staged for higher luminosity LHC operation, will increase trigger acceptance and reduce or eliminate the fake muon trigger rates in the barrel-endcap transition region, corresponding to pseudo-rapidity range 1<|η|<1.3. Low level trigger candidates must be flagged within a maximum latency of 1075 ns, thus imposing stringent signal processing time performance requirements on the readout system in general, and on the digitization electronics in particular. This paper investigates the HPTDC signal latency performance based on a specially designed evaluation board coupled with an external FPGA evaluation board, when operated in triggerless mode, and under hit rate conditions expected in Phase-I. This hardware based study confirms previous simulations and demonstrates that the HPTDC in triggerless operation satisfies the digitization timing requirements in both leading edge and pair modes.

Generation and evaluation of 3D digital casts of maxillary defects based on multisource data registration: A pilot clinical study.

PubMed

Ye, Hongqiang; Ma, Qijun; Hou, Yuezhong; Li, Man; Zhou, Yongsheng

2017-12-01

Digital techniques are not clinically applied for 1-piece maxillary prostheses containing an obturator and removable partial denture retained by the remaining teeth because of the difficulty in obtaining sufficiently accurate 3-dimensional (3D) images. The purpose of this pilot clinical study was to generate 3D digital casts of maxillary defects, including the defective region and the maxillary dentition, based on multisource data registration and to evaluate their effectiveness. Twelve participants with maxillary defects were selected. The maxillofacial region was scanned with spiral computer tomography (CT), and the maxillary arch and palate were scanned using an intraoral optical scanner. The 3D images from the CT and intraoral scanner were registered and merged to form a 3D digital cast of the maxillary defect containing the anatomic structures needed for the maxillary prosthesis. This included the defect cavity, maxillary dentition, and palate. Traditional silicone impressions were also made, and stone casts were poured. The accuracy of the digital cast in comparison with that of the stone cast was evaluated by measuring the distance between 4 anatomic landmarks. Differences and consistencies were assessed using paired Student t tests and the intraclass correlation coefficient (ICC). In 3 participants, physical resin casts were produced by rapid prototyping from digital casts. Based on the resin casts, maxillary prostheses were fabricated by using conventional methods and then evaluated in the participants to assess the clinical applicability of the digital casts. Digital casts of the maxillary defects were generated and contained all the anatomic details needed for the maxillary prosthesis. Comparing the digital and stone casts, a paired Student t test indicated that differences in the linear distances between landmarks were not statistically significant (P>.05). High ICC values (0.977 to 0.998) for the interlandmark distances further indicated the high degree of consistency between the digital and stone casts. The maxillary prostheses showed good clinical effectiveness, indicating that the corresponding digital casts met the requirements for clinical application. Based on multisource data from spiral CT and the intraoral scanner, 3D digital casts of maxillary defects were generated using the registration technique. These casts were consistent with conventional stone casts in terms of accuracy and were suitable for clinical use. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Waveform digitization for high resolution timing detectors with silicon photomultipliers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ronzhin, A.; Albrow, M. G.; Los, S.

2012-03-01

The results of time resolution studies with silicon photomultipliers (SiPMs) read out with high bandwidth constant fraction discrimination electronics were presented earlier [1-3]. Here we describe the application of fast waveform digitization readout based on the DRS4 chip [4], a switched capacitor array (SCA) produced by the Paul Scherrer Institute, to further our goal of developing high time resolution detectors based on SiPMs. The influence of the SiPM signal shape on the time resolution was investigated. Different algorithms to obtain the best time resolution are described, and test beam results are presented.

Navigation and Elctro-Optic Sensor Integration Technology for Fusion of Imagery and Digital Mapping Products

DTIC Science & Technology

1999-08-01

Electro - Optic Sensor Integration Technology (NEOSIT) software application. The design is highly modular and based on COTS tools to facilitate integration with sensors, navigation and digital data sources already installed on different host

A 1024×768-12μm Digital ROIC for uncooled microbolometer FPAs

NASA Astrophysics Data System (ADS)

Eminoglu, Selim

2017-02-01

This paper reports the development of a new digital microbolometer Readout Integrated Circuit (D-ROIC), called MT10212BD. It has a format of 1024 × 768 (XGA) and a pixel pitch of 12μm. MT10212BD is Mikro Tasarim's second 12μm pitch microbolometer ROIC, which is developed specifically for surface micro machined microbolometer detector arrays with small pixel pitch using high-TCR pixel materials, such as VOx and a Si. MT10212BD has an alldigital system on-chip architecture, which generates programmable timing and biasing, and performs 14-bit analog to digital conversion (ADC). The signal processing chain in the ROIC is composed of pixel bias circuitry, integrator based programmable gain amplifier followed by column parallel ADC circuitry. MT10212BD has a serial programming interface that can be used to configure the programmable ROIC features and to load the Non-Uniformity-Correction (NUC) date to the ROIC. MT10212BD has a total of 8 high-speed serial digital video outputs, which can be programmed to operate in the 2, 4, and 8-output modes and can support frames rates above 60 fps. The high-speed serial digital outputs supports data rates as high as 400 Mega-bits/s, when operated at 50 MHz system clock frequency. There is an on-chip phase-locked-loop (PLL) based timing circuitry to generate the high speed clocks used in the ROIC. The ROIC is designed to support pixel resistance values ranging from 30KΩ to 90kΩ, with a nominal value of 60KΩ. The ROIC has a globally programmable gain in the column readout, which can be adjusted based on the detector resistance value.

Digital Biomass Accumulation Using High-Throughput Plant Phenotype Data Analysis.

PubMed

Rahaman, Md Matiur; Ahsan, Md Asif; Gillani, Zeeshan; Chen, Ming

2017-09-01

Biomass is an important phenotypic trait in functional ecology and growth analysis. The typical methods for measuring biomass are destructive, and they require numerous individuals to be cultivated for repeated measurements. With the advent of image-based high-throughput plant phenotyping facilities, non-destructive biomass measuring methods have attempted to overcome this problem. Thus, the estimation of plant biomass of individual plants from their digital images is becoming more important. In this paper, we propose an approach to biomass estimation based on image derived phenotypic traits. Several image-based biomass studies state that the estimation of plant biomass is only a linear function of the projected plant area in images. However, we modeled the plant volume as a function of plant area, plant compactness, and plant age to generalize the linear biomass model. The obtained results confirm the proposed model and can explain most of the observed variance during image-derived biomass estimation. Moreover, a small difference was observed between actual and estimated digital biomass, which indicates that our proposed approach can be used to estimate digital biomass accurately.

Creating Collaborative and Convenient Learning Environment Using Cloud-Based Moodle LMS: An Instructor and Administrator Perspective

ERIC Educational Resources Information Center

Kumar, Vikas; Sharma, Deepika

2016-01-01

Students in the digital era are habitual of using digital devices not only for playing and interacting with their friends and peers, but also as a tool for education and learning. These digital natives are highly obsessed with the internet driven portable devices and always demand for a multimedia rich content. This specific demand needs to be…

A low-cost digital filing system for echocardiography data with MPEG4 compression and its application to remote diagnosis.

PubMed

Umeda, Akira; Iwata, Yasushi; Okada, Yasumasa; Shimada, Megumi; Baba, Akiyasu; Minatogawa, Yasuyuki; Yamada, Takayasu; Chino, Masao; Watanabe, Takafumi; Akaishi, Makoto

2004-12-01

The high cost of digital echocardiographs and the large size of data files hinder the adoption of remote diagnosis of digitized echocardiography data. We have developed a low-cost digital filing system for echocardiography data. In this system, data from a conventional analog echocardiograph are captured using a personal computer (PC) equipped with an analog-to-digital converter board. Motion picture data are promptly compressed using a moving pictures expert group (MPEG) 4 codec. The digitized data with preliminary reports obtained in a rural hospital are then sent to cardiologists at distant urban general hospitals via the internet. The cardiologists can evaluate the data using widely available movie-viewing software (Windows Media Player). The diagnostic accuracy of this double-check system was confirmed by comparison with ordinary super-VHS videotapes. We have demonstrated that digitization of echocardiography data from a conventional analog echocardiograph and MPEG 4 compression can be performed using an ordinary PC-based system, and that this system enables highly efficient digital storage and remote diagnosis at low cost.

High-sensitivity assay for Hg (II) and Ag (I) ion detection: A new class of droplet digital PCR logic gates for an intelligent DNA calculator.

PubMed

Cheng, Nan; Zhu, Pengyu; Xu, Yuancong; Huang, Kunlun; Luo, Yunbo; Yang, Zhansen; Xu, Wentao

2016-10-15

The first example of droplet digital PCR logic gates ("YES", "OR" and "AND") for Hg (II) and Ag (I) ion detection has been constructed based on two amplification events triggered by a metal-ion-mediated base mispairing (T-Hg(II)-T and C-Ag(I)-C). In this work, Hg(II) and Ag(I) were used as the input, and the "true" hierarchical colors or "false" green were the output. Through accurate molecular recognition and high sensitivity amplification, positive droplets were generated by droplet digital PCR and viewed as the basis of hierarchical digital signals. Based on this principle, YES gate for Hg(II) (or Ag(I)) detection, OR gate for Hg(II) or Ag(I) detection and AND gate for Hg(II) and Ag(I) detection were developed, and their sensitively and selectivity were reported. The results indicate that the ddPCR logic system developed based on the different indicators for Hg(II) and Ag(I) ions provides a useful strategy for developing advanced detection methods, which are promising for multiplex metal ion analysis and intelligent DNA calculator design applications. Copyright © 2016 Elsevier B.V. All rights reserved.

Digital micromirror device-based laser-illumination Fourier ptychographic microscopy

PubMed Central

Kuang, Cuifang; Ma, Ye; Zhou, Renjie; Lee, Justin; Barbastathis, George; Dasari, Ramachandra R.; Yaqoob, Zahid; So, Peter T. C.

2015-01-01

We report a novel approach to Fourier ptychographic microscopy (FPM) by using a digital micromirror device (DMD) and a coherent laser source (532 nm) for generating spatially modulated sample illumination. Previously demonstrated FPM systems are all based on partially-coherent illumination, which offers limited throughput due to insufficient brightness. Our FPM employs a high power coherent laser source to enable shot-noise limited high-speed imaging. For the first time, a digital micromirror device (DMD), imaged onto the back focal plane of the illumination objective, is used to generate spatially modulated sample illumination field for ptychography. By coding the on/off states of the micromirrors, the illumination plane wave angle can be varied at speeds more than 4 kHz. A set of intensity images, resulting from different oblique illuminations, are used to numerically reconstruct one high-resolution image without obvious laser speckle. Experiments were conducted using a USAF resolution target and a fiber sample, demonstrating high-resolution imaging capability of our system. We envision that our approach, if combined with a coded-aperture compressive-sensing algorithm, will further improve the imaging speed in DMD-based FPM systems. PMID:26480361

Digital micromirror device-based laser-illumination Fourier ptychographic microscopy.

PubMed

Kuang, Cuifang; Ma, Ye; Zhou, Renjie; Lee, Justin; Barbastathis, George; Dasari, Ramachandra R; Yaqoob, Zahid; So, Peter T C

2015-10-19

We report a novel approach to Fourier ptychographic microscopy (FPM) by using a digital micromirror device (DMD) and a coherent laser source (532 nm) for generating spatially modulated sample illumination. Previously demonstrated FPM systems are all based on partially-coherent illumination, which offers limited throughput due to insufficient brightness. Our FPM employs a high power coherent laser source to enable shot-noise limited high-speed imaging. For the first time, a digital micromirror device (DMD), imaged onto the back focal plane of the illumination objective, is used to generate spatially modulated sample illumination field for ptychography. By coding the on/off states of the micromirrors, the illumination plane wave angle can be varied at speeds more than 4 kHz. A set of intensity images, resulting from different oblique illuminations, are used to numerically reconstruct one high-resolution image without obvious laser speckle. Experiments were conducted using a USAF resolution target and a fiber sample, demonstrating high-resolution imaging capability of our system. We envision that our approach, if combined with a coded-aperture compressive-sensing algorithm, will further improve the imaging speed in DMD-based FPM systems.

Method and apparatus for digitally based high speed x-ray spectrometer for direct coupled use with continuous discharge preamplifiers

DOEpatents

Warburton, W.K.

1998-06-30

A high speed, digitally based, signal processing system is disclosed which accepts directly coupled input data from a detector with a continuous discharge type preamplifier and produces a spectral analysis of the x-rays illuminating the detector. The system`s principal elements are an analog signal conditioning section, a combinatorial logic section which implements digital triangular filtering and pileup inspection, and a microprocessor which accepts values captured by the logic section and uses them to compute x-ray energy values. Operating without pole-zero correction, the system achieves high resolution by capturing, in conjunction with each peak value from the digital filter, an associated value of the unfiltered signal, and using this latter signal to correct the former for errors which arise from its local slope terms. This correction greatly reduces both energy resolution degradation and peak centroid shifting in the output spectrum as a function of input count rate. When the noise of this correction is excessive, a modification allows two filtered averages of the signal to be captured and a corrected peak amplitude computed therefrom. 14 figs.

Method and apparatus for digitally based high speed x-ray spectrometer for direct coupled use with continuous discharge preamplifiers

DOEpatents

Warburton, William K.

1998-01-01

A high speed, digitally based, signal processing system which accepts directly coupled input data from a detector with a continuous discharge type preamplifier and produces a spectral analysis of the x-rays illuminating the detector. The system's principal elements are an analog signal conditioning section, a combinatorial logic section which implements digital triangular filtering and pileup inspection, and a microprocessor which accepts values captured by the logic section and uses them to compute x-ray energy values. Operating without pole-zero correction, the system achieves high resolution by capturing, in conjunction with each peak value from the digital filter, an associated value of the unfiltered signal, and using this latter signal to correct the former for errors which arise from its local slope terms. This correction greatly reduces both energy resolution degradation and peak centroid shifting in the output spectrum as a function of input count rate. When the noise of this correction is excessive, a modification allows two filtered averages of the signal to be captured and a corrected peak amplitude computed therefrom.

High-speed single-pixel digital holography

NASA Astrophysics Data System (ADS)

González, Humberto; Martínez-León, Lluís.; Soldevila, Fernando; Araiza-Esquivel, Ma.; Tajahuerce, Enrique; Lancis, Jesús

2017-06-01

The complete phase and amplitude information of biological specimens can be easily determined by phase-shifting digital holography. Spatial light modulators (SLMs) based on liquid crystal technology, with a frame-rate around 60 Hz, have been employed in digital holography. In contrast, digital micro-mirror devices (DMDs) can reach frame rates up to 22 kHz. A method proposed by Lee to design computer generated holograms (CGHs) permits the use of such binary amplitude modulators as phase-modulation devices. Single-pixel imaging techniques record images by sampling the object with a sequence of micro-structured light patterns and using a simple photodetector. Our group has reported some approaches combining single-pixel imaging and phase-shifting digital holography. In this communication, we review these techniques and present the possibility of a high-speed single-pixel phase-shifting digital holography system with phase-encoded illumination. This system is based on a Mach-Zehnder interferometer, with a DMD acting as the modulator for projecting the sampling patterns on the object and also being used for phase-shifting. The proposed sampling functions are phaseencoded Hadamard patterns generated through a Lee hologram approach. The method allows the recording of the complex amplitude distribution of an object at high speed on account of the high frame rates of the DMD. Reconstruction may take just a few seconds. Besides, the optical setup is envisaged as a true adaptive system, which is able to measure the aberration induced by the optical system in the absence of a sample object, and then to compensate the wavefront in the phasemodulation stage.

User`s manual for the CDC-1 digitizer controller

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferron, J.R.

1994-09-01

A detailed description of how to use the CDC-1 digitizer controller is given. The CDC-1 is used with the CAMAC format digitizer models in the TRAQ series (manufactured by DSP Technology Inc.), the DAD-1 data acquisition daughter board, and the Intel i860-based SuperCard-2 (manufactured, by CSP Inc.) to form a high speed data acquisition and real time analysis system. Data can be transferred to the memory on the SuperCard-2 at a rate as high as 40 million 14-bit samples per second. Depending on the model of TRAQ digitizer in use, digitizing rates up to 3.33 MHz are supported (with eightmore » data channels), or, for instance, at a sample rate of 100 kHz, 384 data channels can be acquired.« less

Full range line-field parallel swept source imaging utilizing digital refocusing

NASA Astrophysics Data System (ADS)

Fechtig, Daniel J.; Kumar, Abhishek; Drexler, Wolfgang; Leitgeb, Rainer A.

2015-12-01

We present geometric optics-based refocusing applied to a novel off-axis line-field parallel swept source imaging (LPSI) system. LPSI is an imaging modality based on line-field swept source optical coherence tomography, which permits 3-D imaging at acquisition speeds of up to 1 MHz. The digital refocusing algorithm applies a defocus-correcting phase term to the Fourier representation of complex-valued interferometric image data, which is based on the geometrical optics information of the LPSI system. We introduce the off-axis LPSI system configuration, the digital refocusing algorithm and demonstrate the effectiveness of our method for refocusing volumetric images of technical and biological samples. An increase of effective in-focus depth range from 255 μm to 4.7 mm is achieved. The recovery of the full in-focus depth range might be especially valuable for future high-speed and high-resolution diagnostic applications of LPSI in ophthalmology.

High-speed line-scan camera with digital time delay integration

NASA Astrophysics Data System (ADS)

Bodenstorfer, Ernst; Fürtler, Johannes; Brodersen, Jörg; Mayer, Konrad J.; Eckel, Christian; Gravogl, Klaus; Nachtnebel, Herbert

2007-02-01

Dealing with high-speed image acquisition and processing systems, the speed of operation is often limited by the amount of available light, due to short exposure times. Therefore, high-speed applications often use line-scan cameras, based on charge-coupled device (CCD) sensors with time delayed integration (TDI). Synchronous shift and accumulation of photoelectric charges on the CCD chip - according to the objects' movement - result in a longer effective exposure time without introducing additional motion blur. This paper presents a high-speed color line-scan camera based on a commercial complementary metal oxide semiconductor (CMOS) area image sensor with a Bayer filter matrix and a field programmable gate array (FPGA). The camera implements a digital equivalent to the TDI effect exploited with CCD cameras. The proposed design benefits from the high frame rates of CMOS sensors and from the possibility of arbitrarily addressing the rows of the sensor's pixel array. For the digital TDI just a small number of rows are read out from the area sensor which are then shifted and accumulated according to the movement of the inspected objects. This paper gives a detailed description of the digital TDI algorithm implemented on the FPGA. Relevant aspects for the practical application are discussed and key features of the camera are listed.

Novel Tool for Complete Digitization of Paper Electrocardiography Data.

PubMed

Ravichandran, Lakshminarayan; Harless, Chris; Shah, Amit J; Wick, Carson A; Mcclellan, James H; Tridandapani, Srini

We present a Matlab-based tool to convert electrocardiography (ECG) information from paper charts into digital ECG signals. The tool can be used for long-term retrospective studies of cardiac patients to study the evolving features with prognostic value. To perform the conversion, we: 1) detect the graphical grid on ECG charts using grayscale thresholding; 2) digitize the ECG signal based on its contour using a column-wise pixel scan; and 3) use template-based optical character recognition to extract patient demographic information from the paper ECG in order to interface the data with the patients' medical record. To validate the digitization technique: 1) correlation between the digital signals and signals digitized from paper ECG are performed and 2) clinically significant ECG parameters are measured and compared from both the paper-based ECG signals and the digitized ECG. The validation demonstrates a correlation value of 0.85-0.9 between the digital ECG signal and the signal digitized from the paper ECG. There is a high correlation in the clinical parameters between the ECG information from the paper charts and digitized signal, with intra-observer and inter-observer correlations of 0.8-0.9 (p < 0.05), and kappa statistics ranging from 0.85 (inter-observer) to 1.00 (intra-observer). The important features of the ECG signal, especially the QRST complex and the associated intervals, are preserved by obtaining the contour from the paper ECG. The differences between the measures of clinically important features extracted from the original signal and the reconstructed signal are insignificant, thus highlighting the accuracy of this technique. Using this type of ECG digitization tool to carry out retrospective studies on large databases, which rely on paper ECG records, studies of emerging ECG features can be performed. In addition, this tool can be used to potentially integrate digitized ECG information with digital ECG analysis programs and with the patient's electronic medical record.

Superconducting Digital Multiplexers for Sensor Arrays

NASA Technical Reports Server (NTRS)

Kadin, Alan M.; Brock, Darren K.; Gupta, Deepnarayan

2004-01-01

Arrays of cryogenic microbolometers and other cryogenic detectors are being developed for infrared imaging. If the signal from each sensor is amplified, multiplexed, and digitized using superconducting electronics, then this data can be efficiently read out to ambient temperature with a minimum of noise and thermal load. HYPRES is developing an integrated system based on SQUID amplifiers, a high-resolution analog-to-digital converter (ADC) based on RSFQ (rapid single flux quantum) logic, and a clocked RSFQ multiplexer. The ADC and SQUIDs have already been demonstrated for other projects, so this paper will focus on new results of a digital multiplexer. Several test circuits have been fabricated using Nb Josephson technology and are about to be tested at T = 4.2 K, with a more complete prototype in preparation.

A digital front-end and readout microsystem for calorimetry at LHC

NASA Astrophysics Data System (ADS)

Alippi, C.; Appelquist, G.; Berglund, S.; Bohm, C.; Breveglieri, L.; Brigati, S.; Carlson, P.; Cattaneo, P.; Dadda, L.; David, J.; Del Buono, L.; Dell'Acqua, A.; Engström, M.; Fumagalli, G.; Gatti, U.; Genat, J. F.; Goggi, G.; Hansen, M.; Hentzell, H.; Höglund, I.; Inkinen, S.; Kerek, A.; Lebbolo, H.; LeDortz, O.; Lofstedt, B.; Maloberti, F.; Nayman, P.; Persson, S.-T.; Piuri, V.; Salice, F.; Sami, M.; Savoy-Navarro, A.; Stefanelli, R.; Sundblad, R.; Svensson, C.; Torelli, G.; Vanuxem, J. P.; Yamdagni, N.; Yuan, J.; Zitoun, R.

1994-04-01

A digital solution to the front-end electronics for calorimetric detectors at future supercolliders is presented. The solution is based on high speed {A}/{D} converters, a fully programmable pipeline/digital filter chain and local intelligence. Questions of error correction, fault-tolerance and system redundancy are also being considered. A system integration of a multichannel device in a multichip, Silicon-on-Silicon Microsystem hybrid, is used. This solution allows a new level of integration of complex analogue and digital functions, with an excellent flexibility in mixing technologies for the different functional blocks. It also allows a high degree of programmability at both the function and the system level, and offers the possibility of customising the microsystem with detector-specific functions.

Modified signed-digit trinary addition using synthetic wavelet filter

NASA Astrophysics Data System (ADS)

Iftekharuddin, K. M.; Razzaque, M. A.

2000-09-01

The modified signed-digit (MSD) number system has been a topic of interest as it allows for parallel carry-free addition of two numbers for digital optical computing. In this paper, harmonic wavelet joint transform (HWJT)-based correlation technique is introduced for optical implementation of MSD trinary adder implementation. The realization of the carry-propagation-free addition of MSD trinary numerals is demonstrated using synthetic HWJT correlator model. It is also shown that the proposed synthetic wavelet filter-based correlator shows high performance in logic processing. Simulation results are presented to validate the performance of the proposed technique.

A Synthetic Quadrature Phase Detector/Demodulator for Fourier Transform Transform Spectrometers

NASA Technical Reports Server (NTRS)

Campbell, Joel

2008-01-01

A method is developed to demodulate (velocity correct) Fourier transform spectrometer (FTS) data that is taken with an analog to digital converter that digitizes equally spaced in time. This method makes it possible to use simple low cost, high resolution audio digitizers to record high quality data without the need for an event timer or quadrature laser hardware, and makes it possible to use a metrology laser of any wavelength. The reduced parts count and simplicity implementation makes it an attractive alternative in space based applications when compared to previous methods such as the Brault algorithm.

Digital multicolor printing: state of the art and future challenges

NASA Astrophysics Data System (ADS)

Kipphan, Helmut

1995-04-01

During the last 5 years, digital techniques have become extremely important in the graphic arts industry. All sections in the production flow for producing multicolor printed products - prepress, printing and postpress - are influenced by digitalization, in an evolutionary and revolutionary way. New equipment and network techniques bring all the sections closer together. The focus is put on high-quality multicolor printing, together with high productivity. Conventional offset printing technology is compared with the leading nonimpact printing technologies. Computer to press is contrasted with computer to print techniques. The newest available digital multicolor presses are described - the direct imaging offset printing press from HEIDELBERG with new laser imaging technique as well as the INDIGO and XEIKON presses based on electrophotography. Regarding technical specifications, economic calculations and print quality, it is worked out that each technique has its own market segments. An outlook is given for future computer to press techniques and the potential of nonimpact printing technologies for advanced high-speed multicolor computer to print equipment. Synergy effects from the NIP-technologies to the conventional printing technologies and vice versa are possible for building up innovative new products, for example hybrid printing systems. It is also shown that there is potential for improving the print quality, based on special screening algorithms, and a higher number of grey levels per pixel by using NIP-technologies. As an intermediate step in digitalization of the production flow, but also as an economical solution computer to plate equipment is described. By producing printed products totally in a digital way, digital color proofing as well as color management systems are needed. The newest high-tech equipment using NIP-technologies for producing proofs is explained. All in all it is shown that the state of the art in digital multicolor printing has reached a very high level in technology, productivity and quality, but that there is still space for improvements and innovations. Manufacturers of equipment and producers of printed products can take part in a successful evolution-changes, chances and challenges must be recognized and considered for future orientated activities and investments.

The performance and limitations of FPGA-based digital servos for atomic, molecular, and optical physics experiments

NASA Astrophysics Data System (ADS)

Yu, Shi Jing; Fajeau, Emma; Liu, Lin Qiao; Jones, David J.; Madison, Kirk W.

2018-02-01

In this work, we address the advantages, limitations, and technical subtleties of employing field programmable gate array (FPGA)-based digital servos for high-bandwidth feedback control of lasers in atomic, molecular, and optical physics experiments. Specifically, we provide the results of benchmark performance tests in experimental setups including noise, bandwidth, and dynamic range for two digital servos built with low and mid-range priced FPGA development platforms. The digital servo results are compared to results obtained from a commercially available state-of-the-art analog servo using the same plant for control (intensity stabilization). The digital servos have feedback bandwidths of 2.5 MHz, limited by the total signal latency, and we demonstrate improvements beyond the transfer function offered by the analog servo including a three-pole filter and a two-pole filter with phase compensation to suppress resonances. We also discuss limitations of our FPGA-servo implementation and general considerations when designing and using digital servos.

The performance and limitations of FPGA-based digital servos for atomic, molecular, and optical physics experiments.

PubMed

Yu, Shi Jing; Fajeau, Emma; Liu, Lin Qiao; Jones, David J; Madison, Kirk W

2018-02-01

In this work, we address the advantages, limitations, and technical subtleties of employing field programmable gate array (FPGA)-based digital servos for high-bandwidth feedback control of lasers in atomic, molecular, and optical physics experiments. Specifically, we provide the results of benchmark performance tests in experimental setups including noise, bandwidth, and dynamic range for two digital servos built with low and mid-range priced FPGA development platforms. The digital servo results are compared to results obtained from a commercially available state-of-the-art analog servo using the same plant for control (intensity stabilization). The digital servos have feedback bandwidths of 2.5 MHz, limited by the total signal latency, and we demonstrate improvements beyond the transfer function offered by the analog servo including a three-pole filter and a two-pole filter with phase compensation to suppress resonances. We also discuss limitations of our FPGA-servo implementation and general considerations when designing and using digital servos.

The Digital Slide Archive: A Software Platform for Management, Integration, and Analysis of Histology for Cancer Research.

PubMed

Gutman, David A; Khalilia, Mohammed; Lee, Sanghoon; Nalisnik, Michael; Mullen, Zach; Beezley, Jonathan; Chittajallu, Deepak R; Manthey, David; Cooper, Lee A D

2017-11-01

Tissue-based cancer studies can generate large amounts of histology data in the form of glass slides. These slides contain important diagnostic, prognostic, and biological information and can be digitized into expansive and high-resolution whole-slide images using slide-scanning devices. Effectively utilizing digital pathology data in cancer research requires the ability to manage, visualize, share, and perform quantitative analysis on these large amounts of image data, tasks that are often complex and difficult for investigators with the current state of commercial digital pathology software. In this article, we describe the Digital Slide Archive (DSA), an open-source web-based platform for digital pathology. DSA allows investigators to manage large collections of histologic images and integrate them with clinical and genomic metadata. The open-source model enables DSA to be extended to provide additional capabilities. Cancer Res; 77(21); e75-78. ©2017 AACR . ©2017 American Association for Cancer Research.

Computer aided system for segmentation and visualization of microcalcifications in digital mammograms.

PubMed

Reljin, Branimir; Milosević, Zorica; Stojić, Tomislav; Reljin, Irini

2009-01-01

Two methods for segmentation and visualization of microcalcifications in digital or digitized mammograms are described. First method is based on modern mathematical morphology, while the second one uses the multifractal approach. In the first method, by using an appropriate combination of some morphological operations, high local contrast enhancement, followed by significant suppression of background tissue, irrespective of its radiology density, is obtained. By iterative procedure, this method highly emphasizes only small bright details, possible microcalcifications. In a multifractal approach, from initial mammogram image, a corresponding multifractal "images" are created, from which a radiologist has a freedom to change the level of segmentation. An appropriate user friendly computer aided visualization (CAV) system with embedded two methods is realized. The interactive approach enables the physician to control the level and the quality of segmentation. Suggested methods were tested through mammograms from MIAS database as a gold standard, and from clinical praxis, using digitized films and digital images from full field digital mammograph.

High-rate x-ray spectroscopy in mammography with a CdTe detector: a digital pulse processing approach.

PubMed

Abbene, L; Gerardi, G; Principato, F; Del Sordo, S; Ienzi, R; Raso, G

2010-12-01

Direct measurement of mammographic x-ray spectra under clinical conditions is a difficult task due to the high fluence rate of the x-ray beams as well as the limits in the development of high resolution detection systems in a high counting rate environment. In this work we present a detection system, based on a CdTe detector and an innovative digital pulse processing (DPP) system, for high-rate x-ray spectroscopy in mammography. The DPP system performs a digital pile-up inspection and a digital pulse height analysis of the detector signals, digitized through a 14-bit, 100 MHz digitizer, for x-ray spectroscopy even at high photon counting rates. We investigated on the response of the digital detection system both at low (150 cps) and at high photon counting rates (up to 500 kcps) by using monoenergetic x-ray sources and a nonclinical molybdenum anode x-ray tube. Clinical molybdenum x-ray spectrum measurements were also performed by using a pinhole collimator and a custom alignment device. The detection system shows excellent performance up to 512 kcps with an energy resolution of 4.08% FWHM at 22.1 keV. Despite the high photon counting rate (up to 453 kcps), the molybdenum x-ray spectra, measured under clinical conditions, are characterized by a low number of pile-up events. The agreement between the attenuation curves and the half value layer values, obtained from the measured spectra, simulated spectra, and from the exposure values directly measured with an ionization chamber, also shows the accuracy of the measurements. These results make the proposed detection system a very attractive tool for both laboratory research and advanced quality controls in mammography.

Do digital innovations for HIV and sexually transmitted infections work? Results from a systematic review (1996-2017)

PubMed Central

Daher, Jana; Vijh, Rohit; Linthwaite, Blake; Dave, Sailly; Kim, John; Dheda, Keertan; Peter, Trevor; Pai, Nitika Pant

2017-01-01

Objective Digital innovations with internet/mobile phones offer a potential cost-saving solution for overburdened health systems with high service delivery costs to improve efficiency of HIV/STI (sexually transmitted infections) control initiatives. However, their overall evidence has not yet been appraised. We evaluated the feasibility and impact of all digital innovations for all HIV/STIs. Design Systematic review. Setting/participants All settings/all participants. Intervention We classified digital innovations into (1) mobile health-based (mHealth: SMS (short message service)/phone calls), (2) internet-based mobile and/or electronic health (mHealth/eHealth: social media, avatar-guided computer programs, websites, mobile applications, streamed soap opera videos) and (3) combined innovations (included both SMS/phone calls and internet-based mHealth/eHealth). Primary and secondary outcome measures Feasibility, acceptability, impact. Methods We searched databases MEDLINE via PubMed, Embase, Cochrane CENTRAL and Web of Science, abstracted data, explored heterogeneity, performed a random effects subgroup analysis. Results We reviewed 99 studies, 63 (64%) were from America/Europe, 36 (36%) from Africa/Asia; 79% (79/99) were clinical trials; 84% (83/99) evaluated impact. Of innovations, mHealth based: 70% (69/99); internet based: 21% (21/99); combined: 9% (9/99). All digital innovations were highly accepted (26/31; 84%), and feasible (20/31; 65%). Regarding impacted measures, mHealth-based innovations (SMS) significantly improved antiretroviral therapy (ART) adherence (pooled OR=2.15(95%CI: 1.18 to 3.91)) and clinic attendance rates (pooled OR=1.76(95%CI: 1.28, 2.42)); internet-based innovations improved clinic attendance (6/6), ART adherence (4/4), self-care (1/1), while reducing risk (5/5); combined innovations increased clinic attendance, ART adherence, partner notifications and self-care. Confounding (68%) and selection bias (66%) were observed in observational studies and attrition bias in 31% of clinical trials. Conclusion Digital innovations were acceptable, feasible and generated impact. A trend towards the use of internet-based and combined (internet and mobile) innovations was noted. Large scale-up studies of high quality, with new integrated impact metrics, and cost-effectiveness are needed. Findings will appeal to all stakeholders in the HIV/STI global initiatives space. PMID:29101138

Do digital innovations for HIV and sexually transmitted infections work? Results from a systematic review (1996-2017).

PubMed

Daher, Jana; Vijh, Rohit; Linthwaite, Blake; Dave, Sailly; Kim, John; Dheda, Keertan; Peter, Trevor; Pai, Nitika Pant

2017-11-03

Digital innovations with internet/mobile phones offer a potential cost-saving solution for overburdened health systems with high service delivery costs to improve efficiency of HIV/STI (sexually transmitted infections) control initiatives. However, their overall evidence has not yet been appraised. We evaluated the feasibility and impact of all digital innovations for all HIV/STIs. Systematic review. All settings/all participants. We classified digital innovations into (1) mobile health-based (mHealth: SMS (short message service)/phone calls), (2) internet-based mobile and/or electronic health (mHealth/eHealth: social media, avatar-guided computer programs, websites, mobile applications, streamed soap opera videos) and (3) combined innovations (included both SMS/phone calls and internet-based mHealth/eHealth). Feasibility, acceptability, impact. We searched databases MEDLINE via PubMed, Embase, Cochrane CENTRAL and Web of Science, abstracted data, explored heterogeneity, performed a random effects subgroup analysis. We reviewed 99 studies, 63 (64%) were from America/Europe, 36 (36%) from Africa/Asia; 79% (79/99) were clinical trials; 84% (83/99) evaluated impact. Of innovations, mHealth based: 70% (69/99); internet based: 21% (21/99); combined: 9% (9/99).All digital innovations were highly accepted (26/31; 84%), and feasible (20/31; 65%). Regarding impacted measures, mHealth-based innovations (SMS) significantly improved antiretroviral therapy (ART) adherence (pooled OR=2.15(95%CI: 1.18 to 3.91)) and clinic attendance rates (pooled OR=1.76(95%CI: 1.28, 2.42)); internet-based innovations improved clinic attendance (6/6), ART adherence (4/4), self-care (1/1), while reducing risk (5/5); combined innovations increased clinic attendance, ART adherence, partner notifications and self-care. Confounding (68%) and selection bias (66%) were observed in observational studies and attrition bias in 31% of clinical trials. Digital innovations were acceptable, feasible and generated impact. A trend towards the use of internet-based and combined (internet and mobile) innovations was noted. Large scale-up studies of high quality, with new integrated impact metrics, and cost-effectiveness are needed. Findings will appeal to all stakeholders in the HIV/STI global initiatives space. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Digitally controlled analog proportional-integral-derivative (PID) controller for high-speed scanning probe microscopy

NASA Astrophysics Data System (ADS)

Dukic, Maja; Todorov, Vencislav; Andany, Santiago; Nievergelt, Adrian P.; Yang, Chen; Hosseini, Nahid; Fantner, Georg E.

2017-12-01

Nearly all scanning probe microscopes (SPMs) contain a feedback controller, which is used to move the scanner in the direction of the z-axis in order to maintain a constant setpoint based on the tip-sample interaction. The most frequently used feedback controller in SPMs is the proportional-integral (PI) controller. The bandwidth of the PI controller presents one of the speed limiting factors in high-speed SPMs, where higher bandwidths enable faster scanning speeds and higher imaging resolution. Most SPM systems use digital signal processor-based PI feedback controllers, which require analog-to-digital and digital-to-analog converters. These converters introduce additional feedback delays which limit the achievable imaging speed and resolution. In this paper, we present a digitally controlled analog proportional-integral-derivative (PID) controller. The controller implementation allows tunability of the PID gains over a large amplification and frequency range, while also providing precise control of the system and reproducibility of the gain parameters. By using the analog PID controller, we were able to perform successful atomic force microscopy imaging of a standard silicon calibration grating at line rates up to several kHz.

Digitally controlled analog proportional-integral-derivative (PID) controller for high-speed scanning probe microscopy.

PubMed

Dukic, Maja; Todorov, Vencislav; Andany, Santiago; Nievergelt, Adrian P; Yang, Chen; Hosseini, Nahid; Fantner, Georg E

2017-12-01

Nearly all scanning probe microscopes (SPMs) contain a feedback controller, which is used to move the scanner in the direction of the z-axis in order to maintain a constant setpoint based on the tip-sample interaction. The most frequently used feedback controller in SPMs is the proportional-integral (PI) controller. The bandwidth of the PI controller presents one of the speed limiting factors in high-speed SPMs, where higher bandwidths enable faster scanning speeds and higher imaging resolution. Most SPM systems use digital signal processor-based PI feedback controllers, which require analog-to-digital and digital-to-analog converters. These converters introduce additional feedback delays which limit the achievable imaging speed and resolution. In this paper, we present a digitally controlled analog proportional-integral-derivative (PID) controller. The controller implementation allows tunability of the PID gains over a large amplification and frequency range, while also providing precise control of the system and reproducibility of the gain parameters. By using the analog PID controller, we were able to perform successful atomic force microscopy imaging of a standard silicon calibration grating at line rates up to several kHz.

CMOS cassette for digital upgrade of film-based mammography systems

NASA Astrophysics Data System (ADS)

Baysal, Mehmet A.; Toker, Emre

2006-03-01

While full-field digital mammography (FFDM) technology is gaining clinical acceptance, the overwhelming majority (96%) of the installed base of mammography systems are conventional film-screen (FSM) systems. A high performance, and economical digital cassette based product to conveniently upgrade FSM systems to FFDM would accelerate the adoption of FFDM, and make the clinical and technical advantages of FFDM available to a larger population of women. The planned FFDM cassette is based on our commercial Digital Radiography (DR) cassette for 10 cm x 10 cm field-of-view spot imaging and specimen radiography, utilizing a 150 micron columnar CsI(Tl) scintillator and 48 micron active-pixel CMOS sensor modules. Unlike a Computer Radiography (CR) cassette, which requires an external digitizer, our DR cassette transfers acquired images to a display workstation within approximately 5 seconds of exposure, greatly enhancing patient flow. We will present the physical performance of our prototype system against other FFDM systems in clinical use today, using established objective criteria such as the Modulation Transfer Function (MTF), Detective Quantum Efficiency (DQE), and subjective criteria, such as a contrast-detail (CD-MAM) observer performance study. Driven by the strong demand from the computer industry, CMOS technology is one of the lowest cost, and the most readily accessible technologies available for FFDM today. Recent popular use of CMOS imagers in high-end consumer cameras have also resulted in significant advances in the imaging performance of CMOS sensors against rivaling CCD sensors. This study promises to take advantage of these unique features to develop the first CMOS based FFDM upgrade cassette.

The x-ray light valve: a low-cost, digital radiographic imaging system-spatial resolution

NASA Astrophysics Data System (ADS)

MacDougall, Robert D.; Koprinarov, Ivaylo; Webster, Christie A.; Rowlands, J. A.

2007-03-01

In recent years, new x-ray radiographic systems based on large area flat panel technology have revolutionized our capability to produce digital x-ray radiographic images. However, these active matrix flat panel imagers (AMFPIs) are extraordinarily expensive compared to the systems they are replacing. Thus there is a need for a low cost digital imaging system for general applications in radiology. Different approaches have been considered to make lower cost, integrated x-ray imaging devices for digital radiography, including: scanned projection x-ray, an integrated approach based on computed radiography technology and optically demagnified x-ray screen/CCD systems. These approaches suffer from either high cost or high mechanical complexity and do not have the image quality of AMFPIs. We have identified a new approach - the X-ray Light Valve (XLV). The XLV has the potential to achieve the immediate readout in an integrated system with image quality comparable to AMFPIs. The XLV concept combines three well-established and hence lowcost technologies: an amorphous selenium (a-Se) layer to convert x-rays to image charge, a liquid crystal (LC) cell as an analog display, and an optical scanner for image digitization. Here we investigate the spatial resolution possible with XLV systems. Both a-Se and LC cells have both been shown separately to have inherently very high spatial resolution. Due to the close electrostatic coupling in the XLV, it can be expected that the spatial resolution of this system will also be very high. A prototype XLV was made and a typical office scanner was used for image digitization. The Modulation Transfer Function was measured and the limiting factor was seen to be the optical scanner. However, even with this limitation the XLV system is able to meet or exceed the resolution requirements for chest radiography.

Experimental investigation of analog and digital dimming techniques on photometric performance of an indoor Visible Light Communication (VLC) system

NASA Astrophysics Data System (ADS)

Zafar, Fahad; Kalavally, Vineetha; Bakaul, Masuduzzaman; Parthiban, R.

2015-09-01

For making commercial implementation of light emitting diode (LED) based visible light communication (VLC) systems feasible, it is necessary to incorporate it with dimming schemes which will provide energy savings, moods and increase the aesthetic value of the places using this technology. There are two general methods which are used to dim LEDs commonly categorized as analog and digital dimming. Incorporating fast data transmission with these techniques is a key challenge in VLC. In this paper, digital and analog dimming for a 10 Mb/s non return to zero on-off keying (NRZ-OOK) based VLC system is experimentally investigated considering both photometric and communicative parameters. A spectrophotometer was used for photometric analysis and a line of sight (LOS) configuration in the presence of ambient light was used for analyzing communication parameters. Based on the experimental results, it was determined that digital dimming scheme is preferable for use in indoor VLC systems requiring high dimming precision and data transmission at lower brightness levels. On the other hand, analog dimming scheme is a cost effective solution for high speed systems where dimming precision is insignificant.

Digital Liberal Arts at a Distance: A Consortium-Wide Approach

ERIC Educational Resources Information Center

Pearson, Ellen Holmes; McClurken, Jeffrey; Bailey, Claire

2016-01-01

Over the past decade, campus-based digital liberal arts projects have extended high-impact undergraduate research across disciplines and beyond the traditional print medium for the production and dissemination of knowledge. But many small- to medium-sized liberal arts colleges, and especially public liberal arts colleges, often lack the…

Using PBL to Deliver Course in Digital Electronics

ERIC Educational Resources Information Center

Mantri, Archana; Dutt, Sunil; Gupta, J. P; Chitkara, Madhu

2009-01-01

Problem Based Learning (PBL) has proven to be a highly successful pedagogical model in many educational fields, although it is comparatively uncommon in technical education. It goes beyond the typical teaching methodology by promoting student interaction. This paper presents a PBL trial applied to an undergraduate Digital Electronics course in the…

An automatic fuzzy-based multi-temporal brain digital subtraction angiography image fusion algorithm using curvelet transform and content selection strategy.

PubMed

Momeni, Saba; Pourghassem, Hossein

2014-08-01

Recently image fusion has prominent role in medical image processing and is useful to diagnose and treat many diseases. Digital subtraction angiography is one of the most applicable imaging to diagnose brain vascular diseases and radiosurgery of brain. This paper proposes an automatic fuzzy-based multi-temporal fusion algorithm for 2-D digital subtraction angiography images. In this algorithm, for blood vessel map extraction, the valuable frames of brain angiography video are automatically determined to form the digital subtraction angiography images based on a novel definition of vessel dispersion generated by injected contrast material. Our proposed fusion scheme contains different fusion methods for high and low frequency contents based on the coefficient characteristic of wrapping second generation of curvelet transform and a novel content selection strategy. Our proposed content selection strategy is defined based on sample correlation of the curvelet transform coefficients. In our proposed fuzzy-based fusion scheme, the selection of curvelet coefficients are optimized by applying weighted averaging and maximum selection rules for the high frequency coefficients. For low frequency coefficients, the maximum selection rule based on local energy criterion is applied to better visual perception. Our proposed fusion algorithm is evaluated on a perfect brain angiography image dataset consisting of one hundred 2-D internal carotid rotational angiography videos. The obtained results demonstrate the effectiveness and efficiency of our proposed fusion algorithm in comparison with common and basic fusion algorithms.

Application of real-time digitization techniques in beam measurement for accelerators

NASA Astrophysics Data System (ADS)

Zhao, Lei; Zhan, Lin-Song; Gao, Xing-Shun; Liu, Shu-Bin; An, Qi

2016-04-01

Beam measurement is very important for accelerators. In this paper, modern digital beam measurement techniques based on IQ (In-phase & Quadrature-phase) analysis are discussed. Based on this method and high-speed high-resolution analog-to-digital conversion, we have completed three beam measurement electronics systems designed for the China Spallation Neutron Source (CSNS), Shanghai Synchrotron Radiation Facility (SSRF), and Accelerator Driven Sub-critical system (ADS). Core techniques of hardware design and real-time system calibration are discussed, and performance test results of these three instruments are also presented. Supported by National Natural Science Foundation of China (11205153, 10875119), Knowledge Innovation Program of the Chinese Academy of Sciences (KJCX2-YW-N27), and the Fundamental Research Funds for the Central Universities (WK2030040029),and the CAS Center for Excellence in Particle Physics (CCEPP).

DMD-based quantitative phase microscopy and optical diffraction tomography

NASA Astrophysics Data System (ADS)

Zhou, Renjie

2018-02-01

Digital micromirror devices (DMDs), which offer high speed and high degree of freedoms in steering light illuminations, have been increasingly applied to optical microscopy systems in recent years. Lately, we introduced DMDs into digital holography to enable new imaging modalities and break existing imaging limitations. In this paper, we will first present our progress in using DMDs for demonstrating laser-illumination Fourier ptychographic microscopy (FPM) with shotnoise limited detection. After that, we will present a novel common-path quantitative phase microscopy (QPM) system based on using a DMD. Building on those early developments, a DMD-based high speed optical diffraction tomography (ODT) system has been recently demonstrated, and the results will also be presented. This ODT system is able to achieve video-rate 3D refractive-index imaging, which can potentially enable observations of high-speed 3D sample structural changes.

High performance Si nanowire field-effect-transistors based on a CMOS inverter with tunable threshold voltage.

PubMed

Van, Ngoc Huynh; Lee, Jae-Hyun; Sohn, Jung Inn; Cha, Seung Nam; Whang, Dongmok; Kim, Jong Min; Kang, Dae Joon

2014-05-21

We successfully fabricated nanowire-based complementary metal-oxide semiconductor (NWCMOS) inverter devices by utilizing n- and p-type Si nanowire field-effect-transistors (NWFETs) via a low-temperature fabrication processing technique. We demonstrate that NWCMOS inverter devices can be operated at less than 1 V, a significantly lower voltage than that of typical thin-film based complementary metal-oxide semiconductor (CMOS) inverter devices. This low-voltage operation was accomplished by controlling the threshold voltage of the n-type Si NWFETs through effective management of the nanowire (NW) doping concentration, while realizing high voltage gain (>10) and ultra-low static power dissipation (≤3 pW) for high-performance digital inverter devices. This result offers a viable means of fabricating high-performance, low-operation voltage, and high-density digital logic circuits using a low-temperature fabrication processing technique suitable for next-generation flexible electronics.

Projection-based motion estimation for cardiac functional analysis with high temporal resolution: a proof-of-concept study with digital phantom experiment

NASA Astrophysics Data System (ADS)

Suzuki, Yuki; Fung, George S. K.; Shen, Zeyang; Otake, Yoshito; Lee, Okkyun; Ciuffo, Luisa; Ashikaga, Hiroshi; Sato, Yoshinobu; Taguchi, Katsuyuki

2017-03-01

Cardiac motion (or functional) analysis has shown promise not only for non-invasive diagnosis of cardiovascular diseases but also for prediction of cardiac future events. Current imaging modalities has limitations that could degrade the accuracy of the analysis indices. In this paper, we present a projection-based motion estimation method for x-ray CT that estimates cardiac motion with high spatio-temporal resolution using projection data and a reference 3D volume image. The experiment using a synthesized digital phantom showed promising results for motion analysis.

Optimal digital dynamical decoupling for general decoherence via Walsh modulation

NASA Astrophysics Data System (ADS)

Qi, Haoyu; Dowling, Jonathan P.; Viola, Lorenza

2017-11-01

We provide a general framework for constructing digital dynamical decoupling sequences based on Walsh modulation—applicable to arbitrary qubit decoherence scenarios. By establishing equivalence between decoupling design based on Walsh functions and on concatenated projections, we identify a family of optimal Walsh sequences, which can be exponentially more efficient, in terms of the required total pulse number, for fixed cancellation order, than known digital sequences based on concatenated design. Optimal sequences for a given cancellation order are highly non-unique—their performance depending sensitively on the control path. We provide an analytic upper bound to the achievable decoupling error and show how sequences within the optimal Walsh family can substantially outperform concatenated decoupling in principle, while respecting realistic timing constraints.

[A digital micromirror device-based Hadamard transform near infrared spectrometer].

PubMed

Liu, Jia; Chen, Fen-Fei; Liao, Cheng-Sheng; Xu, Qian; Zeng, Li-Bo; Wu, Qiong-Shui

2011-10-01

A Hadamard transform near infrared spectrometer based on a digital micromirror device was constructed. The optical signal was collected by optical fiber, a grating was used for light diffraction, a digital micromirror device (DMD) was applied instead of traditional mechanical Hadamard masks for optical modulation, and an InGaAs near infrared detector was used as the optic sensor. The original spectrum was recovered by fast Hadamard transform algrithms. The advantages of the spectrometer, such as high resolution, signal-noise-ratio, stability, sensitivity and response speed were proved by experiments, which indicated that it is very suitable for oil and food-safety applications.

Preparation and Characterization of Soybean Oil-Based Polyurethanes for Digital Doming Applications

PubMed Central

Pantone, Vincenzo; Laurenza, Amelita Grazia; Annese, Cosimo; Fracassi, Francesco; Fini, Paola; Nacci, Angelo; Russo, Antonella; Fusco, Caterina

2017-01-01

Polyurethane-resin doming is currently one of the fastest growing markets in the field of industrial graphics and product identification. Semi-rigid bio-based polyurethanes were prepared deriving from soybean oil as a valuable alternative to fossil materials for digital doming and applied to digital mosaic technology. Bio-resins produced can favorably compete with the analogous fossil polymers, giving high-quality surface coatings (ascertained by SEM analyses). In addition, polyurethane synthesis was accomplished by using a mercury- and tin-free catalyst (the commercially available zinc derivative K22) bringing significant benefits in terms of cost efficiency and eco-sustainability. PMID:28773208

Study of fish response using particle image velocimetry and high-speed, high-resolution imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deng, Z.; Richmond, M. C.; Mueller, R. P.

2004-10-01

Fish swimming has fascinated both engineers and fish biologists for decades. Digital particle image velocimetry (DPIV) and high-speed, high-resolution digital imaging are recently developed analysis tools that can help engineers and biologists better understand how fish respond to turbulent environments. This report details studies to evaluate DPIV. The studies included a review of existing literature on DPIV, preliminary studies to test the feasibility of using DPIV conducted at our Flow Biology Laboratory in Richland, Washington September through December 2003, and applications of high-speed, high-resolution digital imaging with advanced motion analysis to investigations of fish injury mechanisms in turbulent shear flowsmore » and bead trajectories in laboratory physical models. Several conclusions were drawn based on these studies, which are summarized as recommendations for proposed research at the end of this report.« less

Automatic Topography Using High Precision Digital Moire Methods

NASA Astrophysics Data System (ADS)

Yatagai, T.; Idesawa, M.; Saito, S.

1983-07-01

Three types of moire topographic methods using digital techniques are proposed. Deformed gratings obtained by projecting a reference grating onto an object under test are subjected to digital analysis. The electronic analysis procedures of deformed gratings described here enable us to distinguish between depression and elevation of the object, so that automatic measurement of 3-D shapes and automatic moire fringe interpolation are performed. Based on the digital moire methods, we have developed a practical measurement system, with a linear photodiode array on a micro-stage as a scanning image sensor. Examples of fringe analysis in medical applications are presented.

Novel Tool for Complete Digitization of Paper Electrocardiography Data

PubMed Central

Harless, Chris; Shah, Amit J.; Wick, Carson A.; Mcclellan, James H.

2013-01-01

Objective: We present a Matlab-based tool to convert electrocardiography (ECG) information from paper charts into digital ECG signals. The tool can be used for long-term retrospective studies of cardiac patients to study the evolving features with prognostic value. Methods and procedures: To perform the conversion, we: 1) detect the graphical grid on ECG charts using grayscale thresholding; 2) digitize the ECG signal based on its contour using a column-wise pixel scan; and 3) use template-based optical character recognition to extract patient demographic information from the paper ECG in order to interface the data with the patients' medical record. To validate the digitization technique: 1) correlation between the digital signals and signals digitized from paper ECG are performed and 2) clinically significant ECG parameters are measured and compared from both the paper-based ECG signals and the digitized ECG. Results: The validation demonstrates a correlation value of 0.85–0.9 between the digital ECG signal and the signal digitized from the paper ECG. There is a high correlation in the clinical parameters between the ECG information from the paper charts and digitized signal, with intra-observer and inter-observer correlations of 0.8–0.9 \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$({\\rm p}<{0.05})$\\end{document}, and kappa statistics ranging from 0.85 (inter-observer) to 1.00 (intra-observer). Conclusion: The important features of the ECG signal, especially the QRST complex and the associated intervals, are preserved by obtaining the contour from the paper ECG. The differences between the measures of clinically important features extracted from the original signal and the reconstructed signal are insignificant, thus highlighting the accuracy of this technique. Clinical impact: Using this type of ECG digitization tool to carry out retrospective studies on large databases, which rely on paper ECG records, studies of emerging ECG features can be performed. In addition, this tool can be used to potentially integrate digitized ECG information with digital ECG analysis programs and with the patient's electronic medical record. PMID:26594601

An Evaluation of Stereoscopic Digital Mammography for Earlier Detection of Breast Cancer and Reduced Rate of Recall

DTIC Science & Technology

2004-08-01

on a pair of high -resolution, LCD medical monitors. The change to the new workstation has required us to rewrite the software... In the original CRT-based system, the two 7 images forming a stereo pair were displayed alternately on the same CRT face, at a high frame rate (120 Hz...then, separately, receive the stereo screening exam on the research GE digital mammography unit.

An NMR Experiment Based on Off-the-Shelf Digital Data-Acquisition Equipment

ERIC Educational Resources Information Center

Hilty, Christian; Bowen, Sean

2010-01-01

Nuclear magnetic resonance (NMR) poses significant challenges for teaching in the context of an undergraduate laboratory, foremost because of high equipment cost. Current off-the-shelf data-acquisition hardware, however, is sufficiently powerful to constitute the core of a fully digital NMR spectrometer operating at the earth's field. We present…

Design and Optimization of a Light-Emitting Diode Projection Micro-Stereolithography Three-Dimensional Manufacturing System

DTIC Science & Technology

2012-12-11

ment, and difficulties creating high aspect ratio features. In addition, conventional mask-based lithography cannot create curved surfaces in the...There are three types of digital mask technologies: (1) liquid crystal display (LCD); (2) digital micromirror device (DMD); and (3) LCoS. LCD is the

Digital switched hydraulics

NASA Astrophysics Data System (ADS)

Pan, Min; Plummer, Andrew

2018-06-01

This paper reviews recent developments in digital switched hydraulics particularly the switched inertance hydraulic systems (SIHSs). The performance of SIHSs is presented in brief with a discussion of several possible configurations and control strategies. The soft switching technology and high-speed switching valve design techniques are discussed. Challenges and recommendations are given based on the current research achievements.

Accuracy assessment of high frequency 3D ultrasound for digital impression-taking of prepared teeth

NASA Astrophysics Data System (ADS)

Heger, Stefan; Vollborn, Thorsten; Tinschert, Joachim; Wolfart, Stefan; Radermacher, Klaus

2013-03-01

Silicone based impression-taking of prepared teeth followed by plaster casting is well-established but potentially less reliable, error-prone and inefficient, particularly in combination with emerging techniques like computer aided design and manufacturing (CAD/CAM) of dental prosthesis. Intra-oral optical scanners for digital impression-taking have been introduced but until now some drawbacks still exist. Because optical waves can hardly penetrate liquids or soft-tissues, sub-gingival preparations still need to be uncovered invasively prior to scanning. High frequency ultrasound (HFUS) based micro-scanning has been recently investigated as an alternative to optical intra-oral scanning. Ultrasound is less sensitive against oral fluids and in principal able to penetrate gingiva without invasively exposing of sub-gingival preparations. Nevertheless, spatial resolution as well as digitization accuracy of an ultrasound based micro-scanning system remains a critical parameter because the ultrasound wavelength in water-like media such as gingiva is typically smaller than that of optical waves. In this contribution, the in-vitro accuracy of ultrasound based micro-scanning for tooth geometry reconstruction is being investigated and compared to its extra-oral optical counterpart. In order to increase the spatial resolution of the system, 2nd harmonic frequencies from a mechanically driven focused single element transducer were separated and corresponding 3D surface models were calculated for both fundamentals and 2nd harmonics. Measurements on phantoms, model teeth and human teeth were carried out for evaluation of spatial resolution and surface detection accuracy. Comparison of optical and ultrasound digital impression taking indicate that, in terms of accuracy, ultrasound based tooth digitization can be an alternative for optical impression-taking.

Choosing a DIVA: a comparison of emerging digital imagery vegetation analysis techniques

USGS Publications Warehouse

Jorgensen, Christopher F.; Stutzman, Ryan J.; Anderson, Lars C.; Decker, Suzanne E.; Powell, Larkin A.; Schacht, Walter H.; Fontaine, Joseph J.

2013-01-01

Question: What is the precision of five methods of measuring vegetation structure using ground-based digital imagery and processing techniques? Location: Lincoln, Nebraska, USA Methods: Vertical herbaceous cover was recorded using digital imagery techniques at two distinct locations in a mixed-grass prairie. The precision of five ground-based digital imagery vegetation analysis (DIVA) methods for measuring vegetation structure was tested using a split-split plot analysis of covariance. Variability within each DIVA technique was estimated using coefficient of variation of mean percentage cover. Results: Vertical herbaceous cover estimates differed among DIVA techniques. Additionally, environmental conditions affected the vertical vegetation obstruction estimates for certain digital imagery methods, while other techniques were more adept at handling various conditions. Overall, percentage vegetation cover values differed among techniques, but the precision of four of the five techniques was consistently high. Conclusions: DIVA procedures are sufficient for measuring various heights and densities of standing herbaceous cover. Moreover, digital imagery techniques can reduce measurement error associated with multiple observers' standing herbaceous cover estimates, allowing greater opportunity to detect patterns associated with vegetation structure.

Digital learning programs - competition for the classical microscope?

PubMed

Schmidt, Peter

2013-01-01

The development of digital media has been impressive in recent years which is also among the reason for their increasing use in academic teaching. This is especially true for teaching Anatomy and Histology in the first two years in medical and dental curricula. Modern digital technologies allow for efficient, affordable and easily accessible distribution of histological images in high quality. Microscopy depends almost exclusively on such images. Since 20 years numerous digital teaching systems have been developed for this purpose. Respective developments have changed the ways students acquire knowledge and prepare for exams. Teaching staff should adapt lectures, seminars and labs accordingly. As a first step, a collection of high resolution digital microscopic slides was made available for students at the Friedrich-Schiller-University in Jena. The aim of the present study was to evaluate the importance of conventional light microscopy and related technologies in current and future medical and dental education aswell. A survey was done among 172 medical and dental students at the Friedrich-Schiller-University Jena. 51% of students use now frequently new digital media for learning histology in contrast to 5% in the year 2000 [1]. Digital media including Internet, CD- based learning combined with social networks successfully compete with classical light microscopy.

Demosaiced pixel super-resolution in digital holography for multiplexed computational color imaging on-a-chip (Conference Presentation)

NASA Astrophysics Data System (ADS)

Wu, Yichen; Zhang, Yibo; Luo, Wei; Ozcan, Aydogan

2017-03-01

Digital holographic on-chip microscopy achieves large space-bandwidth-products (e.g., >1 billion) by making use of pixel super-resolution techniques. To synthesize a digital holographic color image, one can take three sets of holograms representing the red (R), green (G) and blue (B) parts of the spectrum and digitally combine them to synthesize a color image. The data acquisition efficiency of this sequential illumination process can be improved by 3-fold using wavelength-multiplexed R, G and B illumination that simultaneously illuminates the sample, and using a Bayer color image sensor with known or calibrated transmission spectra to digitally demultiplex these three wavelength channels. This demultiplexing step is conventionally used with interpolation-based Bayer demosaicing methods. However, because the pixels of different color channels on a Bayer image sensor chip are not at the same physical location, conventional interpolation-based demosaicing process generates strong color artifacts, especially at rapidly oscillating hologram fringes, which become even more pronounced through digital wave propagation and phase retrieval processes. Here, we demonstrate that by merging the pixel super-resolution framework into the demultiplexing process, such color artifacts can be greatly suppressed. This novel technique, termed demosaiced pixel super-resolution (D-PSR) for digital holographic imaging, achieves very similar color imaging performance compared to conventional sequential R,G,B illumination, with 3-fold improvement in image acquisition time and data-efficiency. We successfully demonstrated the color imaging performance of this approach by imaging stained Pap smears. The D-PSR technique is broadly applicable to high-throughput, high-resolution digital holographic color microscopy techniques that can be used in resource-limited-settings and point-of-care offices.

A microcontroller-based lock-in amplifier for sub-milliohm resistance measurements.

PubMed

Bengtsson, Lars E

2012-07-01

This paper presents a novel approach to the design of a digital ohmmeter with a resolution of <60 μΩ based on a general-purpose microcontroller and a high-impedance instrumentation amplifier only. The design uses two digital I/O-pins to alternate the current through the sample resistor and combined with a proper firmware routine, the design is a lock-in detector that discriminates any signal that is out of phase/frequency with the reference signal. This makes it possible to selectively detect the μV drop across sample resistors down to 55.6 μΩ using only the current that can be supplied by the digital output pins of a microcontroller. This is achieved without the need for an external reference signal generator and does not rely on the computing processing power of a digital signal processor.

A digital receiver module with direct data acquisition for magnetic resonance imaging systems.

PubMed

Tang, Weinan; Sun, Hongyu; Wang, Weimin

2012-10-01

A digital receiver module for magnetic resonance imaging (MRI) with detailed hardware implementations is presented. The module is based on a direct sampling scheme using the latest mixed-signal circuit design techniques. A single field-programmable gate array chip is employed to perform software-based digital down conversion for radio frequency signals. The modular architecture of the receiver allows multiple acquisition channels to be implemented on a highly integrated printed circuit board. To maintain the phase coherence of the receiver and the exciter in the context of direct sampling, an effective phase synchronization method was proposed to achieve a phase deviation as small as 0.09°. The performance of the described receiver module was verified in the experiments for both low- and high-field (0.5 T and 1.5 T) MRI scanners and was compared to a modern commercial MRI receiver system.

Subranging technique using superconducting technology

DOEpatents

Gupta, Deepnarayan

2003-01-01

Subranging techniques using "digital SQUIDs" are used to design systems with large dynamic range, high resolution and large bandwidth. Analog-to-digital converters (ADCs) embodying the invention include a first SQUID based "coarse" resolution circuit and a second SQUID based "fine" resolution circuit to convert an analog input signal into "coarse" and "fine" digital signals for subsequent processing. In one embodiment, an ADC includes circuitry for supplying an analog input signal to an input coil having at least a first inductive section and a second inductive section. A first superconducting quantum interference device (SQUID) is coupled to the first inductive section and a second SQUID is coupled to the second inductive section. The first SQUID is designed to produce "coarse" (large amplitude, low resolution) output signals and the second SQUID is designed to produce "fine" (low amplitude, high resolution) output signals in response to the analog input signals.

High accuracy digital aging monitor based on PLL-VCO circuit

NASA Astrophysics Data System (ADS)

Yuejun, Zhang; Zhidi, Jiang; Pengjun, Wang; Xuelong, Zhang

2015-01-01

As the manufacturing process is scaled down to the nanoscale, the aging phenomenon significantly affects the reliability and lifetime of integrated circuits. Consequently, the precise measurement of digital CMOS aging is a key aspect of nanoscale aging tolerant circuit design. This paper proposes a high accuracy digital aging monitor using phase-locked loop and voltage-controlled oscillator (PLL-VCO) circuit. The proposed monitor eliminates the circuit self-aging effect for the characteristic of PLL, whose frequency has no relationship with circuit aging phenomenon. The PLL-VCO monitor is implemented in TSMC low power 65 nm CMOS technology, and its area occupies 303.28 × 298.94 μm2. After accelerating aging tests, the experimental results show that PLL-VCO monitor improves accuracy about high temperature by 2.4% and high voltage by 18.7%.

Introduction to the Special Issue on Digital Signal Processing in Radio Astronomy

NASA Astrophysics Data System (ADS)

Price, D. C.; Kocz, J.; Bailes, M.; Greenhill, L. J.

2016-03-01

Advances in astronomy are intimately linked to advances in digital signal processing (DSP). This special issue is focused upon advances in DSP within radio astronomy. The trend within that community is to use off-the-shelf digital hardware where possible and leverage advances in high performance computing. In particular, graphics processing units (GPUs) and field programmable gate arrays (FPGAs) are being used in place of application-specific circuits (ASICs); high-speed Ethernet and Infiniband are being used for interconnect in place of custom backplanes. Further, to lower hurdles in digital engineering, communities have designed and released general-purpose FPGA-based DSP systems, such as the CASPER ROACH board, ASTRON Uniboard, and CSIRO Redback board. In this introductory paper, we give a brief historical overview, a summary of recent trends, and provide an outlook on future directions.

Bandwidth Efficient Wireless Digital Modem Developed

NASA Technical Reports Server (NTRS)

Kifle, Muli

1999-01-01

NASA Lewis Research Center has developed a digital approach for broadcasting highfidelity audio (nearly compact disk (CD) quality sound) in the commercial frequencymodulated (FM) broadcast band. This digital approach provides a means of achieving high data transmission rates with low hardware complexity--including low mass, size, and power consumption. Lewis has completed the design and prototype development of a bandwidth-efficient digital modem (modulator and demodulator) that uses a spectrally efficient modulation scheme: 16-ary rectangular quadrature amplitude modulation, or 16- ary QAM. The digital implementation is based strictly on inexpensive, commercial off-theshelf digital signal processing (DSP) hardware to perform up and down conversions and pulse shaping. The digital modem transmits data at rates up to 76 kilobits per second (kbps), which is almost 3 times faster than standard 28.8-kbps telephone modems. In addition, the modem offers improved power and spectral performance, flexible operation, and low-cost implementation.

Configurable analog-digital conversion using the neural engineering framework

PubMed Central

Mayr, Christian G.; Partzsch, Johannes; Noack, Marko; Schüffny, Rene

2014-01-01

Efficient Analog-Digital Converters (ADC) are one of the mainstays of mixed-signal integrated circuit design. Besides the conventional ADCs used in mainstream ICs, there have been various attempts in the past to utilize neuromorphic networks to accomplish an efficient crossing between analog and digital domains, i.e., to build neurally inspired ADCs. Generally, these have suffered from the same problems as conventional ADCs, that is they require high-precision, handcrafted analog circuits and are thus not technology portable. In this paper, we present an ADC based on the Neural Engineering Framework (NEF). It carries out a large fraction of the overall ADC process in the digital domain, i.e., it is easily portable across technologies. The analog-digital conversion takes full advantage of the high degree of parallelism inherent in neuromorphic networks, making for a very scalable ADC. In addition, it has a number of features not commonly found in conventional ADCs, such as a runtime reconfigurability of the ADC sampling rate, resolution and transfer characteristic. PMID:25100933

A class of systolizable IIR digital filters and its design for proper scaling and minimum output roundoff noise

NASA Technical Reports Server (NTRS)

Lei, Shaw-Min; Yao, Kung

1990-01-01

A class of infinite impulse response (IIR) digital filters with a systolizable structure is proposed and its synthesis is investigated. The systolizable structure consists of pipelineable regular modules with local connections and is suitable for VLSI implementation. It is capable of achieving high performance as well as high throughput. This class of filter structure provides certain degrees of freedom that can be used to obtain some desirable properties for the filter. Techniques of evaluating the internal signal powers and the output roundoff noise of the proposed filter structure are developed. Based upon these techniques, a well-scaled IIR digital filter with minimum output roundoff noise is designed using a local optimization approach. The internal signals of all the modes of this filter are scaled to unity in the l2-norm sense. Compared to the Rao-Kailath (1984) orthogonal digital filter and the Gray-Markel (1973) normalized-lattice digital filter, this filter has better scaling properties and lower output roundoff noise.

High resolution upgrade of the ATF damping ring BPM system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Terunuma, N.; Urakawa, J.; /KEK, Tsukuba

2008-05-01

A beam position monitor (BPM) upgrade at the KEK Accelerator Test Facility (ATF) damping ring has been accomplished in its first stage, carried out by a KEK/FNAL/SLAC collaboration under the umbrella of the global ILC R&D effort. The upgrade consists of a high resolution, high reproducibility read-out system, based on analog and digital downconversion techniques, digital signal processing, and also tests a new automatic gain error correction schema. The technical concept and realization, as well as preliminary results of beam studies are presented.

A Subsystem Test Bed for Chinese Spectral Radioheliograph

NASA Astrophysics Data System (ADS)

Zhao, An; Yan, Yihua; Wang, Wei

2014-11-01

The Chinese Spectral Radioheliograph is a solar dedicated radio interferometric array that will produce high spatial resolution, high temporal resolution, and high spectral resolution images of the Sun simultaneously in decimetre and centimetre wave range. Digital processing of intermediate frequency signal is an important part in a radio telescope. This paper describes a flexible and high-speed digital down conversion system for the CSRH by applying complex mixing, parallel filtering, and extracting algorithms to process IF signal at the time of being designed and incorporates canonic-signed digit coding and bit-plane method to improve program efficiency. The DDC system is intended to be a subsystem test bed for simulation and testing for CSRH. Software algorithms for simulation and hardware language algorithms based on FPGA are written which use less hardware resources and at the same time achieve high performances such as processing high-speed data flow (1 GHz) with 10 MHz spectral resolution. An experiment with the test bed is illustrated by using geostationary satellite data observed on March 20, 2014. Due to the easy alterability of the algorithms on FPGA, the data can be recomputed with different digital signal processing algorithms for selecting optimum algorithm.

Optical system design of dynamic infrared scene projector based on DMD

NASA Astrophysics Data System (ADS)

Lu, Jing; Fu, Yuegang; Liu, Zhiying; Li, Yandong

2014-09-01

Infrared scene simulator is now widely used to simulate infrared scene practicality in the laboratory, which can greatly reduce the research cost of the optical electrical system and offer economical experiment environment. With the advantage of large dynamic range and high spatial resolution, dynamic infrared projection technology, which is the key part of the infrared scene simulator, based on digital micro-mirror device (DMD) has been rapidly developed and widely applied in recent years. In this paper, the principle of the digital micro-mirror device is briefly introduced and the characteristics of the DLP (Digital Light Procession) system based on digital micromirror device (DMD) are analyzed. The projection system worked at 8~12μm with 1024×768 pixel DMD is designed by ZEMAX. The MTF curve is close to the diffraction limited curve and the radius of the spot diagram is smaller than that of the airy disk. The result indicates that the system meets the design requirements.

Atomized scan strategy for high definition for VR application

NASA Astrophysics Data System (ADS)

Huang, Shuping; Ran, Feng; Ji, Yuan; Chen, Wendong

2017-10-01

Silicon-based OLED (Organic Light Emitting Display) microdisplay technology begins to attract people's attention in the emerging VR and AR devices. The high display frame refresh rate is an important solution to alleviate the dizziness in VR applications. Traditional display circuit drivers use the analog method or the digital PWM method that follow the serial scan order from the first pixel to the last pixel by using the shift registers. This paper proposes a novel atomized scan strategy based on the digital fractal scan strategy using the pseudo-random scan order. It can be used to realize the high frame refresh rate with the moderate pixel clock frequency in the high definition OLED microdisplay. The linearity of the gray level is also improved compared with the Z fractal scan strategy.

ChiMS: Open-source instrument control software platform on LabVIEW for imaging/depth profiling mass spectrometers.

PubMed

Cui, Yang; Hanley, Luke

2015-06-01

ChiMS is an open-source data acquisition and control software program written within LabVIEW for high speed imaging and depth profiling mass spectrometers. ChiMS can also transfer large datasets from a digitizer to computer memory at high repetition rate, save data to hard disk at high throughput, and perform high speed data processing. The data acquisition mode generally simulates a digital oscilloscope, but with peripheral devices integrated for control as well as advanced data sorting and processing capabilities. Customized user-designed experiments can be easily written based on several included templates. ChiMS is additionally well suited to non-laser based mass spectrometers imaging and various other experiments in laser physics, physical chemistry, and surface science.

ChiMS: Open-source instrument control software platform on LabVIEW for imaging/depth profiling mass spectrometers

PubMed Central

Cui, Yang; Hanley, Luke

2015-01-01

ChiMS is an open-source data acquisition and control software program written within LabVIEW for high speed imaging and depth profiling mass spectrometers. ChiMS can also transfer large datasets from a digitizer to computer memory at high repetition rate, save data to hard disk at high throughput, and perform high speed data processing. The data acquisition mode generally simulates a digital oscilloscope, but with peripheral devices integrated for control as well as advanced data sorting and processing capabilities. Customized user-designed experiments can be easily written based on several included templates. ChiMS is additionally well suited to non-laser based mass spectrometers imaging and various other experiments in laser physics, physical chemistry, and surface science. PMID:26133872

ChiMS: Open-source instrument control software platform on LabVIEW for imaging/depth profiling mass spectrometers

NASA Astrophysics Data System (ADS)

Cui, Yang; Hanley, Luke

2015-06-01

ChiMS is an open-source data acquisition and control software program written within LabVIEW for high speed imaging and depth profiling mass spectrometers. ChiMS can also transfer large datasets from a digitizer to computer memory at high repetition rate, save data to hard disk at high throughput, and perform high speed data processing. The data acquisition mode generally simulates a digital oscilloscope, but with peripheral devices integrated for control as well as advanced data sorting and processing capabilities. Customized user-designed experiments can be easily written based on several included templates. ChiMS is additionally well suited to non-laser based mass spectrometers imaging and various other experiments in laser physics, physical chemistry, and surface science.

High-throughput characterization of film thickness in thin film materials libraries by digital holographic microscopy.

PubMed

Lai, Yiu Wai; Krause, Michael; Savan, Alan; Thienhaus, Sigurd; Koukourakis, Nektarios; Hofmann, Martin R; Ludwig, Alfred

2011-10-01

A high-throughput characterization technique based on digital holography for mapping film thickness in thin-film materials libraries was developed. Digital holographic microscopy is used for fully automatic measurements of the thickness of patterned films with nanometer resolution. The method has several significant advantages over conventional stylus profilometry: it is contactless and fast, substrate bending is compensated, and the experimental setup is simple. Patterned films prepared by different combinatorial thin-film approaches were characterized to investigate and demonstrate this method. The results show that this technique is valuable for the quick, reliable and high-throughput determination of the film thickness distribution in combinatorial materials research. Importantly, it can also be applied to thin films that have been structured by shadow masking.

Feasibility of a GNSS-Probe for Creating Digital Maps of High Accuracy and Integrity

NASA Astrophysics Data System (ADS)

Vartziotis, Dimitris; Poulis, Alkis; Minogiannis, Alexandros; Siozos, Panayiotis; Goudas, Iraklis; Samson, Jaron; Tossaint, Michel

The “ROADSCANNER” project addresses the need for increased accuracy and integrity Digital Maps (DM) utilizing the latest developments in GNSS, in order to provide the required datasets for novel applications, such as navigation based Safety Applications, Advanced Driver Assistance Systems (ADAS) and Digital Automotive Simulations. The activity covered in the current paper is the feasibility study, preliminary tests, initial product design and development plan for an EGNOS enabled vehicle probe. The vehicle probe will be used for generating high accuracy, high integrity and ADAS compatible digital maps of roads, employing a multiple passes methodology supported by sophisticated refinement algorithms. Furthermore, the vehicle probe will be equipped with pavement scanning and other data fusion equipment, in order to produce 3D road surface models compatible with standards of road-tire simulation applications. The project was assigned to NIKI Ltd under the 1st Call for Ideas in the frame of the ESA - Greece Task Force.

Digital differential confocal microscopy based on spatial shift transformation.

PubMed

Liu, J; Wang, Y; Liu, C; Wilson, T; Wang, H; Tan, J

2014-11-01

Differential confocal microscopy is a particularly powerful surface profilometry technique in industrial metrology due to its high axial sensitivity and insensitivity to noise. However, the practical implementation of the technique requires the accurate positioning of point detectors in three-dimensions. We describe a simple alternative based on spatial transformation of a through-focus series of images obtained from a homemade beam scanning confocal microscope. This digital differential confocal microscopy approach is described and compared with the traditional Differential confocal microscopy approach. The ease of use of the digital differential confocal microscopy system is illustrated by performing measurements on a 3D standard specimen. © 2014 The Authors Journal of Microscopy © 2014 Royal Microscopical Society.

A digitally implemented preambleless demodulator for maritime and mobile data communications

NASA Astrophysics Data System (ADS)

Chalmers, Harvey; Shenoy, Ajit; Verahrami, Farhad B.

The hardware design and software algorithms for a low-bit-rate, low-cost, all-digital preambleless demodulator are described. The demodulator operates under severe high-noise conditions, fast Doppler frequency shifts, large frequency offsets, and multipath fading. Sophisticated algorithms, including a fast Fourier transform (FFT)-based burst acquisition algorithm, a cycle-slip resistant carrier phase tracker, an innovative Doppler tracker, and a fast acquisition symbol synchronizer, were developed and extensively simulated for reliable burst reception. The compact digital signal processor (DSP)-based demodulator hardware uses a unique personal computer test interface for downloading test data files. The demodulator test results demonstrate a near-ideal performance within 0.2 dB of theory.

Recognition of digital characteristics based new improved genetic algorithm

NASA Astrophysics Data System (ADS)

Wang, Meng; Xu, Guoqiang; Lin, Zihao

2017-08-01

In the field of digital signal processing, Estimating the characteristics of signal modulation parameters is an significant research direction. The paper determines the set of eigenvalue which can show the difference of the digital signal modulation based on the deep research of the new improved genetic algorithm. Firstly take them as the best gene pool; secondly, The best gene pool will be changed in the genetic evolvement by selecting, overlapping and eliminating each other; Finally, Adapting the strategy of futher enhance competition and punishment to more optimizer the gene pool and ensure each generation are of high quality gene. The simulation results show that this method not only has the global convergence, stability and faster convergence speed.

Parallel PWMs Based Fully Digital Transmitter with Wide Carrier Frequency Range

PubMed Central

Zhou, Bo; Zhang, Kun; Zhou, Wenbiao; Zhang, Yanjun; Liu, Dake

2013-01-01

The carrier-frequency (CF) and intermediate-frequency (IF) pulse-width modulators (PWMs) based on delay lines are proposed, where baseband signals are conveyed by both positions and pulse widths or densities of the carrier clock. By combining IF-PWM and precorrected CF-PWM, a fully digital transmitter with unit-delay autocalibration is implemented in 180 nm CMOS for high reconfiguration. The proposed architecture achieves wide CF range of 2 M–1 GHz, high power efficiency of 70%, and low error vector magnitude (EVM) of 3%, with spectrum purity of 20 dB optimized in comparison to the existing designs. PMID:24223503

A highly accurate wireless digital sun sensor based on profile detecting and detector multiplexing technologies

NASA Astrophysics Data System (ADS)

Wei, Minsong; Xing, Fei; You, Zheng

2017-01-01

The advancing growth of micro- and nano-satellites requires miniaturized sun sensors which could be conveniently applied in the attitude determination subsystem. In this work, a profile detecting technology based high accurate wireless digital sun sensor was proposed, which could transform a two-dimensional image into two-linear profile output so that it can realize a high update rate under a very low power consumption. A multiple spots recovery approach with an asymmetric mask pattern design principle was introduced to fit the multiplexing image detector method for accuracy improvement of the sun sensor within a large Field of View (FOV). A FOV determination principle based on the concept of FOV region was also proposed to facilitate both sub-FOV analysis and the whole FOV determination. A RF MCU, together with solar cells, was utilized to achieve the wireless and self-powered functionality. The prototype of the sun sensor is approximately 10 times lower in size and weight compared with the conventional digital sun sensor (DSS). Test results indicated that the accuracy of the prototype was 0.01° within a cone FOV of 100°. Such an autonomous DSS could be equipped flexibly on a micro- or nano-satellite, especially for highly accurate remote sensing applications.

A low complexity, low spur digital IF conversion circuit for high-fidelity GNSS signal playback

NASA Astrophysics Data System (ADS)

Su, Fei; Ying, Rendong

2016-01-01

A low complexity high efficiency and low spur digital intermediate frequency (IF) conversion circuit is discussed in the paper. This circuit is key element in high-fidelity GNSS signal playback instrument. We analyze the spur performance of a finite state machine (FSM) based numerically controlled oscillators (NCO), by optimization of the control algorithm, a FSM based NCO with 3 quantization stage can achieves 65dB SFDR in the range of the seventh harmonic. Compare with traditional lookup table based NCO design with the same Spurious Free Dynamic Range (SFDR) performance, the logic resource require to implemented the NCO is reduced to 1/3. The proposed design method can be extended to the IF conversion system with good SFDR in the range of higher harmonic components by increasing the quantization stage.

Fast digital noise filter capable of locating spectral peaks and shoulders

NASA Technical Reports Server (NTRS)

Edwards, T. R.; Knight, R. D.

1972-01-01

Experimental data frequently have a poor signal-to-noise ratio which one would like to enhance before analysis. With the data in digital form, this may be accomplished by means of a digital filter. A fast digital filter based upon the principle of least squares and using the techniques of convoluting integers is described. In addition to smoothing, this filter also is capable of accurately and simultaneously locating spectral peaks and shoulders. This technique has been adapted into a computer subroutine, and results of several test cases are shown, including mass spectral data and data from a proportional counter for the High Energy Astronomy Observatory.

Automated full-3D digitization system for documentation of paintings

NASA Astrophysics Data System (ADS)

Karaszewski, Maciej; Adamczyk, Marcin; Sitnik, Robert; Michoński, Jakub; Załuski, Wojciech; Bunsch, Eryk; Bolewicki, Paweł

2013-05-01

In this paper, a fully automated 3D digitization system for documentation of paintings is presented. It consists of a specially designed frame system for secure fixing of painting, a custom designed, structured light-based, high-resolution measurement head with no IR and UV emission. This device is automatically positioned in two axes (parallel to the surface of digitized painting) with additional manual positioning in third, perpendicular axis. Manual change of observation angle is also possible around two axes to re-measure even partially shadowed areas. The whole system is built in a way which provides full protection of digitized object (moving elements cannot reach its vicinity) and is driven by computer-controlled, highly precise servomechanisms. It can be used for automatic (without any user attention) and fast measurement of the paintings with some limitation to their properties: maximum size of the picture is 2000mm x 2000mm (with deviation of flatness smaller than 20mm) Measurement head is automatically calibrated by the system and its possible working volume starts from 50mm x 50mm x 20mm (10000 points per square mm) and ends at 120mm x 80mm x 60mm (2500 points per square mm). The directional measurements obtained with this system are automatically initially aligned due to the measurement head's position coordinates known from servomechanisms. After the whole painting is digitized, the measurements are fine-aligned with color-based ICP algorithm to remove any influence of possible inaccuracy of positioning devices. We present exemplary digitization results along with the discussion about the opportunities of analysis which appear for such high-resolution, 3D computer models of paintings.

Fast, High-Precision Readout Circuit for Detector Arrays

NASA Technical Reports Server (NTRS)

Rider, David M.; Hancock, Bruce R.; Key, Richard W.; Cunningham, Thomas J.; Wrigley, Chris J.; Seshadri, Suresh; Sander, Stanley P.; Blavier, Jean-Francois L.

2013-01-01

The GEO-CAPE mission described in NASA's Earth Science and Applications Decadal Survey requires high spatial, temporal, and spectral resolution measurements to monitor and characterize the rapidly changing chemistry of the troposphere over North and South Americas. High-frame-rate focal plane arrays (FPAs) with many pixels are needed to enable such measurements. A high-throughput digital detector readout integrated circuit (ROIC) that meets the GEO-CAPE FPA needs has been developed, fabricated, and tested. The ROIC is based on an innovative charge integrating, fast, high-precision analog-to-digital circuit that is built into each pixel. The 128×128-pixel ROIC digitizes all 16,384 pixels simultaneously at frame rates up to 16 kHz to provide a completely digital output on a single integrated circuit at an unprecedented rate of 262 million pixels per second. The approach eliminates the need for off focal plane electronics, greatly reducing volume, mass, and power compared to conventional FPA implementations. A focal plane based on this ROIC will require less than 2 W of power on a 1×1-cm integrated circuit. The ROIC is fabricated of silicon using CMOS technology. It is designed to be indium bump bonded to a variety of detector materials including silicon PIN diodes, indium antimonide (InSb), indium gallium arsenide (In- GaAs), and mercury cadmium telluride (HgCdTe) detector arrays to provide coverage over a broad spectral range in the infrared, visible, and ultraviolet spectral ranges.

FPGA-Based Filterbank Implementation for Parallel Digital Signal Processing

NASA Technical Reports Server (NTRS)

Berner, Stephan; DeLeon, Phillip

1999-01-01

One approach to parallel digital signal processing decomposes a high bandwidth signal into multiple lower bandwidth (rate) signals by an analysis bank. After processing, the subband signals are recombined into a fullband output signal by a synthesis bank. This paper describes an implementation of the analysis and synthesis banks using (Field Programmable Gate Arrays) FPGAs.

Using Digital Representations of Practical Production Work for Summative Assessment

ERIC Educational Resources Information Center

Newhouse, C. Paul

2014-01-01

This paper presents the findings of the first phase of a three-year study investigating the efficacy of the digitisation of creative practical work as digital portfolios for the purposes of high-stakes summative assessment. At the same time the paired comparisons method of scoring was tried as an alternative to analytical rubric-based marking…

Designing a Deeply Digital Science Curriculum: Supporting Teacher Learning and Implementation with Organizing Technologies

ERIC Educational Resources Information Center

Leary, Heather; Severance, Samuel; Penuel, William R.; Quigley, David; Sumner, Tamara; Devaul, Holly

2016-01-01

This paper examines the impacts of technology (e.g., Chromebooks, Google Drive) on teacher learning and student activity in the development and implementation of a deeply digital high school biology unit. Using design-based implementation research, teachers co-designed with researchers and curriculum specialists a student-centered unit aligned to…

Testing the Digital Divide: Does Access to High-Quality Use of Technology in Schools Affect Student Achievement?

ERIC Educational Resources Information Center

Talley, Gregory Keith

2012-01-01

This study investigates the relationship between access, use of technology and student achievement in public middle schools in Maryland. The objective of this study was to determine whether a digital divide (differences in access and utilization of technology based on student characteristics of race, socioeconomic status, and gender) exists among…

Wavelet-based reversible watermarking for authentication

NASA Astrophysics Data System (ADS)

Tian, Jun

2002-04-01

In the digital information age, digital content (audio, image, and video) can be easily copied, manipulated, and distributed. Copyright protection and content authentication of digital content has become an urgent problem to content owners and distributors. Digital watermarking has provided a valuable solution to this problem. Based on its application scenario, most digital watermarking methods can be divided into two categories: robust watermarking and fragile watermarking. As a special subset of fragile watermark, reversible watermark (which is also called lossless watermark, invertible watermark, erasable watermark) enables the recovery of the original, unwatermarked content after the watermarked content has been detected to be authentic. Such reversibility to get back unwatermarked content is highly desired in sensitive imagery, such as military data and medical data. In this paper we present a reversible watermarking method based on an integer wavelet transform. We look into the binary representation of each wavelet coefficient and embed an extra bit to expandable wavelet coefficient. The location map of all expanded coefficients will be coded by JBIG2 compression and these coefficient values will be losslessly compressed by arithmetic coding. Besides these two compressed bit streams, an SHA-256 hash of the original image will also be embedded for authentication purpose.

Fuzzy Logic Module of Convolutional Neural Network for Handwritten Digits Recognition

NASA Astrophysics Data System (ADS)

Popko, E. A.; Weinstein, I. A.

2016-08-01

Optical character recognition is one of the important issues in the field of pattern recognition. This paper presents a method for recognizing handwritten digits based on the modeling of convolutional neural network. The integrated fuzzy logic module based on a structural approach was developed. Used system architecture adjusted the output of the neural network to improve quality of symbol identification. It was shown that proposed algorithm was flexible and high recognition rate of 99.23% was achieved.

Realization and optimization of AES algorithm on the TMS320DM6446 based on DaVinci technology

NASA Astrophysics Data System (ADS)

Jia, Wen-bin; Xiao, Fu-hai

2013-03-01

The application of AES algorithm in the digital cinema system avoids video data to be illegal theft or malicious tampering, and solves its security problems. At the same time, in order to meet the requirements of the real-time, scene and transparent encryption of high-speed data streams of audio and video in the information security field, through the in-depth analysis of AES algorithm principle, based on the hardware platform of TMS320DM6446, with the software framework structure of DaVinci, this paper proposes the specific realization methods of AES algorithm in digital video system and its optimization solutions. The test results show digital movies encrypted by AES128 can not play normally, which ensures the security of digital movies. Through the comparison of the performance of AES128 algorithm before optimization and after, the correctness and validity of improved algorithm is verified.

Status of the photomultiplier-based FlashCam camera for the Cherenkov Telescope Array

NASA Astrophysics Data System (ADS)

Pühlhofer, G.; Bauer, C.; Eisenkolb, F.; Florin, D.; Föhr, C.; Gadola, A.; Garrecht, F.; Hermann, G.; Jung, I.; Kalekin, O.; Kalkuhl, C.; Kasperek, J.; Kihm, T.; Koziol, J.; Lahmann, R.; Manalaysay, A.; Marszalek, A.; Rajda, P. J.; Reimer, O.; Romaszkan, W.; Rupinski, M.; Schanz, T.; Schwab, T.; Steiner, S.; Straumann, U.; Tenzer, C.; Vollhardt, A.; Weitzel, Q.; Winiarski, K.; Zietara, K.

2014-07-01

The FlashCam project is preparing a camera prototype around a fully digital FADC-based readout system, for the medium sized telescopes (MST) of the Cherenkov Telescope Array (CTA). The FlashCam design is the first fully digital readout system for Cherenkov cameras, based on commercial FADCs and FPGAs as key components for digitization and triggering, and a high performance camera server as back end. It provides the option to easily implement different types of trigger algorithms as well as digitization and readout scenarios using identical hardware, by simply changing the firmware on the FPGAs. The readout of the front end modules into the camera server is Ethernet-based using standard Ethernet switches and a custom, raw Ethernet protocol. In the current implementation of the system, data transfer and back end processing rates of 3.8 GB/s and 2.4 GB/s have been achieved, respectively. Together with the dead-time-free front end event buffering on the FPGAs, this permits the cameras to operate at trigger rates of up to several ten kHz. In the horizontal architecture of FlashCam, the photon detector plane (PDP), consisting of photon detectors, preamplifiers, high voltage-, control-, and monitoring systems, is a self-contained unit, mechanically detached from the front end modules. It interfaces to the digital readout system via analogue signal transmission. The horizontal integration of FlashCam is expected not only to be more cost efficient, it also allows PDPs with different types of photon detectors to be adapted to the FlashCam readout system. By now, a 144-pixel mini-camera" setup, fully equipped with photomultipliers, PDP electronics, and digitization/ trigger electronics, has been realized and extensively tested. Preparations for a full-scale, 1764 pixel camera mechanics and a cooling system are ongoing. The paper describes the status of the project.

Parallel implementation of all-digital timing recovery for high-speed and real-time optical coherent receivers.

PubMed

Zhou, Xian; Chen, Xue

2011-05-09

The digital coherent receivers combine coherent detection with digital signal processing (DSP) to compensate for transmission impairments, and therefore are a promising candidate for future high-speed optical transmission system. However, the maximum symbol rate supported by such real-time receivers is limited by the processing rate of hardware. In order to cope with this difficulty, the parallel processing algorithms is imperative. In this paper, we propose a novel parallel digital timing recovery loop (PDTRL) based on our previous work. Furthermore, for increasing the dynamic dispersion tolerance range of receivers, we embed a parallel adaptive equalizer in the PDTRL. This parallel joint scheme (PJS) can be used to complete synchronization, equalization and polarization de-multiplexing simultaneously. Finally, we demonstrate that PDTRL and PJS allow the hardware to process 112 Gbit/s POLMUX-DQPSK signal at the hundreds MHz range. © 2011 Optical Society of America

Integration of ground-based laser scanner and aerial digital photogrammetry for topographic modelling of Vesuvio volcano

NASA Astrophysics Data System (ADS)

Pesci, Arianna; Fabris, Massimo; Conforti, Dario; Loddo, Fabiana; Baldi, Paolo; Anzidei, Marco

2007-05-01

This work deals with the integration of different surveying methodologies for the definition of very accurate Digital Terrain Models (DTM) and/or Digital Surface Models (DSM): in particular, the aerial digital photogrammetry and the terrestrial laser scanning were used to survey the Vesuvio volcano, allowing the total coverage of the internal cone and surroundings (the whole surveyed area was about 3 km × 3 km). The possibility to reach a very high precision, especially from the laser scanner data set, allowed a detailed description of the morphology of the volcano. The comparisons of models obtained in repeated surveys allow a detailed map of residuals providing a data set that can be used for detailed studies of the morphological evolution. Moreover, the reflectivity information, highly correlated to materials properties, allows for the measurement and quantification of some morphological variations in areas where structural discontinuities and displacements are present.

Measurement of solar extinction in tower plants with digital cameras

NASA Astrophysics Data System (ADS)

Ballestrín, J.; Monterreal, R.; Carra, M. E.; Fernandez-Reche, J.; Barbero, J.; Marzo, A.

2016-05-01

Atmospheric extinction of solar radiation between the heliostat field and the receiver is accepted as a non-negligible source of energy loss in the increasingly large central receiver plants. However, the reality is that there is currently no reliable measurement method for this quantity and at present these plants are designed, built and operated without knowing this local parameter. Nowadays digital cameras are used in many scientific applications for their ability to convert available light into digital images. Its broad spectral range, high resolution and high signal to noise ratio, make them an interesting device in solar technology. In this work a method for atmospheric extinction measurement based on digital images is presented. The possibility of defining a measurement setup in circumstances similar to those of a tower plant increases the credibility of the method. This procedure is currently being implemented at Plataforma Solar de Almería.

Effect of Body Mass Index on Digital Templating for Total Hip Arthroplasty.

PubMed

Sershon, Robert A; Diaz, Alejandro; Bohl, Daniel D; Levine, Brett R

2017-03-01

Digital templating is becoming more prevalent in orthopedics. Recent investigations report high accuracy using digital templating in total hip arthroplasty (THA); however, the effect of body mass index (BMI) on templating accuracy is not well described. Digital radiographs of 603 consecutive patients (645 hips) undergoing primary THA by a single surgeon were digitally templated using OrthoView (Jacksonville, FL). A 25-mm metallic sphere was used as a calibration marker. Preoperative digital hip templates were compared with the final implant size. Hips were stratified into groups based on BMI: BMI <30 (315), BMI 30-35 (132), BMI 35-40 (97), and BMI >40 (101). Accuracy between templating and final size did not vary by BMI for acetabular or femoral components. Digital templating was within 2 sizes of the final acetabular and femoral implants in 99.1% and 97.1% of cases, respectively. Digital templating is an effective means of predicting the final size of THA components. BMI does not appear to play a major role in altering THA digital templating accuracy. Copyright © 2016 Elsevier Inc. All rights reserved.

A high-efficiency real-time digital signal averager for time-of-flight mass spectrometry.

PubMed

Wang, Yinan; Xu, Hui; Li, Qingjiang; Li, Nan; Huang, Zhengxu; Zhou, Zhen; Liu, Husheng; Sun, Zhaolin; Xu, Xin; Yu, Hongqi; Liu, Haijun; Li, David D-U; Wang, Xi; Dong, Xiuzhen; Gao, Wei

2013-05-30

Analog-to-digital converter (ADC)-based acquisition systems are widely applied in time-of-flight mass spectrometers (TOFMS) due to their ability to record the signal intensity of all ions within the same pulse. However, the acquisition system raises the requirement for data throughput, along with increasing the conversion rate and resolution of the ADC. It is therefore of considerable interest to develop a high-performance real-time acquisition system, which can relieve the limitation of data throughput. We present in this work a high-efficiency real-time digital signal averager, consisting of a signal conditioner, a data conversion module and a signal processing module. Two optimization strategies are implemented using field programmable gate arrays (FPGAs) to enhance the efficiency of the real-time processing. A pipeline procedure is used to reduce the time consumption of the accumulation strategy. To realize continuous data transfer, a high-efficiency transmission strategy is developed, based on a ping-pong procedure. The digital signal averager features good responsiveness, analog bandwidth and dynamic performance. The optimal effective number of bits reaches 6.7 bits. For a 32 µs record length, the averager can realize 100% efficiency with an extraction frequency below 31.23 kHz by modifying the number of accumulation steps. In unit time, the averager yields superior signal-to-noise ratio (SNR) compared with data accumulation in a computer. The digital signal averager is combined with a vacuum ultraviolet single-photon ionization time-of-flight mass spectrometer (VUV-SPI-TOFMS). The efficiency of the real-time processing is tested by analyzing the volatile organic compounds (VOCs) from ordinary printed materials. In these experiments, 22 kinds of compounds are detected, and the dynamic range exceeds 3 orders of magnitude. Copyright © 2013 John Wiley & Sons, Ltd.

Prototyping scalable digital signal processing systems for radio astronomy using dataflow models

NASA Astrophysics Data System (ADS)

Sane, N.; Ford, J.; Harris, A. I.; Bhattacharyya, S. S.

2012-05-01

There is a growing trend toward using high-level tools for design and implementation of radio astronomy digital signal processing (DSP) systems. Such tools, for example, those from the Collaboration for Astronomy Signal Processing and Electronics Research (CASPER), are usually platform-specific, and lack high-level, platform-independent, portable, scalable application specifications. This limits the designer's ability to experiment with designs at a high-level of abstraction and early in the development cycle. We address some of these issues using a model-based design approach employing dataflow models. We demonstrate this approach by applying it to the design of a tunable digital downconverter (TDD) used for narrow-bandwidth spectroscopy. Our design is targeted toward an FPGA platform, called the Interconnect Break-out Board (IBOB), that is available from the CASPER. We use the term TDD to refer to a digital downconverter for which the decimation factor and center frequency can be reconfigured without the need for regenerating the hardware code. Such a design is currently not available in the CASPER DSP library. The work presented in this paper focuses on two aspects. First, we introduce and demonstrate a dataflow-based design approach using the dataflow interchange format (DIF) tool for high-level application specification, and we integrate this approach with the CASPER tool flow. Secondly, we explore the trade-off between the flexibility of TDD designs and the low hardware cost of fixed-configuration digital downconverter (FDD) designs that use the available CASPER DSP library. We further explore this trade-off in the context of a two-stage downconversion scheme employing a combination of TDD or FDD designs.

Digital learning programs - competition for the classical microscope?

PubMed Central

Schmidt, Peter

2013-01-01

The development of digital media has been impressive in recent years which is also among the reason for their increasing use in academic teaching. This is especially true for teaching Anatomy and Histology in the first two years in medical and dental curricula. Modern digital technologies allow for efficient, affordable and easily accessible distribution of histological images in high quality. Microscopy depends almost exclusively on such images. Since 20 years numerous digital teaching systems have been developed for this purpose. Respective developments have changed the ways students acquire knowledge and prepare for exams. Teaching staff should adapt lectures, seminars and labs accordingly. As a first step, a collection of high resolution digital microscopic slides was made available for students at the Friedrich-Schiller-University in Jena. The aim of the present study was to evaluate the importance of conventional light microscopy and related technologies in current and future medical and dental education aswell. A survey was done among 172 medical and dental students at the Friedrich-Schiller-University Jena. 51% of students use now frequently new digital media for learning histology in contrast to 5% in the year 2000 [1]. Digital media including Internet, CD- based learning combined with social networks successfully compete with classical light microscopy. PMID:23467698

Optimized algorithm for the spatial nonuniformity correction of an imaging system based on a charge-coupled device color camera.

PubMed

de Lasarte, Marta; Pujol, Jaume; Arjona, Montserrat; Vilaseca, Meritxell

2007-01-10

We present an optimized linear algorithm for the spatial nonuniformity correction of a CCD color camera's imaging system and the experimental methodology developed for its implementation. We assess the influence of the algorithm's variables on the quality of the correction, that is, the dark image, the base correction image, and the reference level, and the range of application of the correction using a uniform radiance field provided by an integrator cube. The best spatial nonuniformity correction is achieved by having a nonzero dark image, by using an image with a mean digital level placed in the linear response range of the camera as the base correction image and taking the mean digital level of the image as the reference digital level. The response of the CCD color camera's imaging system to the uniform radiance field shows a high level of spatial uniformity after the optimized algorithm has been applied, which also allows us to achieve a high-quality spatial nonuniformity correction of captured images under different exposure conditions.

Measurement of the refractive index of solutions based on digital holographic microscopy

NASA Astrophysics Data System (ADS)

Huang, Sujuan; Wang, Weiping; Zeng, Junzhang; Yan, Cheng; Lin, Yunyi; Wang, Tingyun

2018-01-01

A new approach for the refractive index (RI) measurement of solutions is proposed based on digital holographic microscopy. The experimental system consists of a modified Mach-Zehnder interferometer and related lab-developed analysis software. The high quality digital hologram of the tested solution is obtained by the real-time analysis software, which is firstly encapsulated into a capillary tube, and then the capillary tube is inserted in a matching fluid. An angular spectrum algorithm is adopted to extract the phase distribution from the hologram recorded by a CCD. Based on a capillary multi-layer calculation model, the RI of the tested solution is obtained at high accuracy. The results of transparent glycerol solution measured by the proposed method are more accurate than those measured by the Abbe refractometer. We also measure the RI of translucent magnetic fluid, which is not suitable to be measured by the Abbe refractometer. The relationship between the RI and the concentration of magnetic fluid is experimentally studied, and the results show that the RI is linearly related to the concentration of dilute magnetic fluid.

3D Digital Surveying and Modelling of Cave Geometry: Application to Paleolithic Rock Art.

PubMed

González-Aguilera, Diego; Muñoz-Nieto, Angel; Gómez-Lahoz, Javier; Herrero-Pascual, Jesus; Gutierrez-Alonso, Gabriel

2009-01-01

3D digital surveying and modelling of cave geometry represents a relevant approach for research, management and preservation of our cultural and geological legacy. In this paper, a multi-sensor approach based on a terrestrial laser scanner, a high-resolution digital camera and a total station is presented. Two emblematic caves of Paleolithic human occupation and situated in northern Spain, "Las Caldas" and "Peña de Candamo", have been chosen to put in practise this approach. As a result, an integral and multi-scalable 3D model is generated which may allow other scientists, pre-historians, geologists…, to work on two different levels, integrating different Paleolithic Art datasets: (1) a basic level based on the accurate and metric support provided by the laser scanner; and (2) a advanced level using the range and image-based modelling.

Coherent receiver design based on digital signal processing in optical high-speed intersatellite links with M-phase-shift keying

NASA Astrophysics Data System (ADS)

Schaefer, Semjon; Gregory, Mark; Rosenkranz, Werner

2016-11-01

We present simulative and experimental investigations of different coherent receiver designs for high-speed optical intersatellite links. We focus on frequency offset (FO) compensation in homodyne and intradyne detection systems. The considered laser communication terminal uses an optical phase-locked loop (OPLL), which ensures stable homodyne detection. However, the hardware complexity increases with the modulation order. Therefore, we show that software-based intradyne detection is an attractive alternative for OPLL-based homodyne systems. Our approach is based on digital FO and phase noise compensation, in order to achieve a more flexible coherent detection scheme. Analytic results will further show the theoretical impact of the different detection schemes on the receiver sensitivity. Finally, we compare the schemes in terms of bit error ratio measurements and optimal receiver design.

An analog gamma correction scheme for high dynamic range CMOS logarithmic image sensors.

PubMed

Cao, Yuan; Pan, Xiaofang; Zhao, Xiaojin; Wu, Huisi

2014-12-15

In this paper, a novel analog gamma correction scheme with a logarithmic image sensor dedicated to minimize the quantization noise of the high dynamic applications is presented. The proposed implementation exploits a non-linear voltage-controlled-oscillator (VCO) based analog-to-digital converter (ADC) to perform the gamma correction during the analog-to-digital conversion. As a result, the quantization noise does not increase while the same high dynamic range of logarithmic image sensor is preserved. Moreover, by combining the gamma correction with the analog-to-digital conversion, the silicon area and overall power consumption can be greatly reduced. The proposed gamma correction scheme is validated by the reported simulation results and the experimental results measured for our designed test structure, which is fabricated with 0.35 μm standard complementary-metal-oxide-semiconductor (CMOS) process.

An Analog Gamma Correction Scheme for High Dynamic Range CMOS Logarithmic Image Sensors

PubMed Central

Cao, Yuan; Pan, Xiaofang; Zhao, Xiaojin; Wu, Huisi

2014-01-01

In this paper, a novel analog gamma correction scheme with a logarithmic image sensor dedicated to minimize the quantization noise of the high dynamic applications is presented. The proposed implementation exploits a non-linear voltage-controlled-oscillator (VCO) based analog-to-digital converter (ADC) to perform the gamma correction during the analog-to-digital conversion. As a result, the quantization noise does not increase while the same high dynamic range of logarithmic image sensor is preserved. Moreover, by combining the gamma correction with the analog-to-digital conversion, the silicon area and overall power consumption can be greatly reduced. The proposed gamma correction scheme is validated by the reported simulation results and the experimental results measured for our designed test structure, which is fabricated with 0.35 μm standard complementary-metal-oxide-semiconductor (CMOS) process. PMID:25517692

Finger-Powered Electro-Digital-Microfluidics.

PubMed

Peng, Cheng; Ju, Y Sungtaek

2017-01-01

Portable microfluidic devices are promising for point-of-care (POC) diagnosis and bio- and environmental surveillance in resource-constrained or non-laboratory environments. Lateral-flow devices, some built off paper or strings, have been widely developed but the fixed layouts of their underlying wicking/microchannel structures limit their flexibility and present challenges in implementing multistep reactions. Digital microfluidics can circumvent these difficulties by addressing discrete droplets individually. Existing approaches to digital microfluidics, however, often require bulky power supplies/batteries and high voltage circuits. We present a scheme to drive digital microfluidic devices by converting mechanical energy of human fingers to electrical energy using an array of piezoelectric elements. We describe the integration our scheme into two promising digital microfluidics platforms: one based on the electro-wetting-on-dielectric (EWOD) phenomenon and the other on the electrophoretic control of droplet (EPD). Basic operations of droplet manipulations, such as droplet transport, merging and splitting, are demonstrated using the finger-powered digital-microfluidics.

[Strength and weaknesses of the German digital health economy].

PubMed

Leppert, Florian; Gerlach, Jan; Ostwald, Dennis A; Greiner, Wolfgang

2017-07-26

There are high expectations from digitalization of health care, ehealth and telemedicine. Nevertheless, the diffusion of these services falls short of expectations. This study analyses the strength and weaknesses of the German digital health economy. Thereby, we specially focus on small and medium-sized enterprises (SME). The study is based on a literature review, interviews of experts and a workshop. The digital health economy is influenced by a heterogeneous environment with both promotive and obstructive factors. One of the largest weaknesses results from a lack of business models. There is a lack of possibilities of reimbursement by the Statutory Health Insurance (SHI). In addition, private users only have a small willingness to pay for digital services. The large number of regulations makes the implementation even harder, especially for SMEs. Thus, the current environment hampers fast diffusion of digital services in the German health care market. © Georg Thieme Verlag KG Stuttgart · New York.

Particle identification using digital pulse shape discrimination in a nTD silicon detector with a 1 GHz sampling digitizer

NASA Astrophysics Data System (ADS)

Mahata, K.; Shrivastava, A.; Gore, J. A.; Pandit, S. K.; Parkar, V. V.; Ramachandran, K.; Kumar, A.; Gupta, S.; Patale, P.

2018-06-01

In beam test experiments have been carried out for particle identification using digital pulse shape analysis in a 500 μm thick Neutron Transmutation Doped (nTD) silicon detector with an indigenously developed FPGA based 12 bit resolution, 1 GHz sampling digitizer. The nTD Si detector was used in a low-field injection setup to detect light heavy-ions produced in reactions of ∼ 5 MeV/A 7Li and 12C beams on different targets. Pulse height, rise time and current maximum have been obtained from the digitized charge output of a high bandwidth charge and current sensitive pre-amplifier. Good isotopic separation have been achieved using only the digitized charge output in case of light heavy-ions. The setup can be used for charged particle spectroscopy in nuclear reactions involving light heavy-ions around the Coulomb barrier energies.

Sharing and interoperation of Digital Dongying geospatial data

NASA Astrophysics Data System (ADS)

Zhao, Jun; Liu, Gaohuan; Han, Lit-tao; Zhang, Rui-ju; Wang, Zhi-an

2006-10-01

Digital Dongying project was put forward by Dongying city, Shandong province, and authenticated by Ministry of Information Industry, Ministry of Science and Technology and Ministry of Construction P.R.CHINA in 2002. After five years of building, informationization level of Dongying has reached to the advanced degree. In order to forward the step of digital Dongying building, and to realize geospatial data sharing, geographic information sharing standards are drawn up and applied into realization. Secondly, Digital Dongying Geographic Information Sharing Platform has been constructed and developed, which is a highly integrated platform of WEBGIS. 3S (GIS, GPS, RS), Object oriented RDBMS, Internet, DCOM, etc. It provides an indispensable platform for sharing and interoperation of Digital Dongying Geospatial Data. According to the standards, and based on the platform, sharing and interoperation of "Digital Dongying" geospatial data have come into practice and the good results have been obtained. However, a perfect leadership group is necessary for data sharing and interoperation.

#Eduresistance: A Critical Analysis of the Role of Digital Media in Collective Struggles for Public Education in the Usa

ERIC Educational Resources Information Center

Thapliyal, Nisha

2018-01-01

From Facebook-coordinated high-school walkouts to compelling Internet-based protest art that has accompanied recent teacher strikes, grassroots education activism in the USA has gone digital. Despite the proliferation of research on the mediatisation of education policy, few studies have explored the ways in which activists for public education…

"Put Us on the Map": Place-Based Media Production and Critical Inquiry in CTE

ERIC Educational Resources Information Center

Jocson, Korina M.

2016-01-01

Many young people today are enacting rich literacies in their lives through the use of digital technologies. While this may be so, there is a narrowing of literacy instruction under neoliberal reforms at a time of increasing informational and digital technologies. In this article, the author draws on an ethnographic study of high school multimedia…

Quality of reconstruction of compressed off-axis digital holograms by frequency filtering and wavelets.

PubMed

Cheremkhin, Pavel A; Kurbatova, Ekaterina A

2018-01-01

Compression of digital holograms can significantly help with the storage of objects and data in 2D and 3D form, its transmission, and its reconstruction. Compression of standard images by methods based on wavelets allows high compression ratios (up to 20-50 times) with minimum losses of quality. In the case of digital holograms, application of wavelets directly does not allow high values of compression to be obtained. However, additional preprocessing and postprocessing can afford significant compression of holograms and the acceptable quality of reconstructed images. In this paper application of wavelet transforms for compression of off-axis digital holograms are considered. The combined technique based on zero- and twin-order elimination, wavelet compression of the amplitude and phase components of the obtained Fourier spectrum, and further additional compression of wavelet coefficients by thresholding and quantization is considered. Numerical experiments on reconstruction of images from the compressed holograms are performed. The comparative analysis of applicability of various wavelets and methods of additional compression of wavelet coefficients is performed. Optimum parameters of compression of holograms by the methods can be estimated. Sizes of holographic information were decreased up to 190 times.

Portable color multimedia training systems based on monochrome laptop computers (CBT-in-a-briefcase), with spinoff implications for video uplink and downlink in spaceflight operations

NASA Technical Reports Server (NTRS)

Scott, D. W.

1994-01-01

This report describes efforts to use digital motion video compression technology to develop a highly portable device that would convert 1990-91 era IBM-compatible and/or MacIntosh notebook computers into full-color, motion-video capable multimedia training systems. An architecture was conceived that would permit direct conversion of existing laser-disk-based multimedia courses with little or no reauthoring. The project did not physically demonstrate certain critical video keying techniques, but their implementation should be feasible. This investigation of digital motion video has spawned two significant spaceflight projects at MSFC: one to downlink multiple high-quality video signals from Spacelab, and the other to uplink videoconference-quality video in realtime and high quality video off-line, plus investigate interactive, multimedia-based techniques for enhancing onboard science operations. Other airborne or spaceborne spinoffs are possible.

High-Speed Current dq PI Controller for Vector Controlled PMSM Drive

PubMed Central

Reaz, Mamun Bin Ibne; Rahman, Labonnah Farzana; Chang, Tae Gyu

2014-01-01

High-speed current controller for vector controlled permanent magnet synchronous motor (PMSM) is presented. The controller is developed based on modular design for faster calculation and uses fixed-point proportional-integral (PI) method for improved accuracy. Current dq controller is usually implemented in digital signal processor (DSP) based computer. However, DSP based solutions are reaching their physical limits, which are few microseconds. Besides, digital solutions suffer from high implementation cost. In this research, the overall controller is realizing in field programmable gate array (FPGA). FPGA implementation of the overall controlling algorithm will certainly trim down the execution time significantly to guarantee the steadiness of the motor. Agilent 16821A Logic Analyzer is employed to validate the result of the implemented design in FPGA. Experimental results indicate that the proposed current dq PI controller needs only 50 ns of execution time in 40 MHz clock, which is the lowest computational cycle for the era. PMID:24574913

Java-based cryptosystem for PACS and tele-imaging

NASA Astrophysics Data System (ADS)

Tjandra, Donny; Wong, Stephen T. C.; Yu, Yuan-Pin

1998-07-01

Traditional PACS systems are based on two-tier client server architectures, and require the use of costly, high-end client workstations for image viewing. Consequently, PACS systems using the two-tier architecture do not scale well as data increases in size and complexity. Furthermore, use of dedicated viewing workstations incurs costs in deployment and maintenance. To address these issues, the use of digital library technologies, such as the World Wide Web, Java, and CORBA, is being explored to distribute PACS data to serve a broader range of healthcare providers in an economic and efficient manner. Integration of PACS systems with digital library technologies allows access to medical information through open networks such as the Internet. However, use of open networks to transmit medical data introduces problems with maintaining privacy and integrity of patient information. Cryptography and digital timestamping is used to protect sensitive information from unauthorized access or tampering. A major concern when using cryptography and digital timestamping is the performance degradation associated with the mathematical calculations needed to encrypt/decrypt an image dataset, or to calculate the hash value of an image. The performance issue is compounded by the extra layer associated with the CORBA middleware, and the use of programming languages interpreted at the client side, such as Java. This paper study the extent to which Java-based cryptography and digital timestamping affects performance in a PACS system integrated with digital library technologies.

Accuracy of DSM based on digital aerial image matching. (Polish Title: Dokładność NMPT tworzonego metodą automatycznego dopasowania cyfrowych zdjęć lotniczych)

NASA Astrophysics Data System (ADS)

Kubalska, J. L.; Preuss, R.

2013-12-01

Digital Surface Models (DSM) are used in GIS data bases as single product more often. They are also necessary to create other products such as3D city models, true-ortho and object-oriented classification. This article presents results of DSM generation for classification of vegetation in urban areas. Source data allowed producing DSM with using of image matching method and ALS data. The creation of DSM from digital images, obtained by Ultra Cam-D digital Vexcel camera, was carried out in Match-T by INPHO. This program optimizes the configuration of images matching process, which ensures high accuracy and minimize gap areas. The analysis of the accuracy of this process was made by comparison of DSM generated in Match-T with DSM generated from ALS data. Because of further purpose of generated DSM it was decided to create model in GRID structure with cell size of 1 m. With this parameter differential model from both DSMs was also built that allowed determining the relative accuracy of the compared models. The analysis indicates that the generation of DSM with multi-image matching method is competitive for the same surface model creation from ALS data. Thus, when digital images with high overlap are available, the additional registration of ALS data seems to be unnecessary.

Projection displays and MEMS: timely convergence for a bright future

NASA Astrophysics Data System (ADS)

Hornbeck, Larry J.

1995-09-01

Projection displays and microelectromechanical systems (MEMS) have evolved independently, occasionally crossing paths as early as the 1950s. But the commercially viable use of MEMS for projection displays has been illusive until the recent invention of Texas Instruments Digital Light Processing TM (DLP) technology. DLP technology is based on the Digital Micromirror DeviceTM (DMD) microchip, a MEMS technology that is a semiconductor digital light switch that precisely controls a light source for projection display and hardcopy applications. DLP technology provides a unique business opportunity because of the timely convergence of market needs and technology advances. The world is rapidly moving to an all- digital communications and entertainment infrastructure. In the near future, most of the technologies necessary for this infrastrucutre will be available at the right performance and price levels. This will make commercially viable an all-digital chain (capture, compression, transmission, reception decompression, hearing, and viewing). Unfortunately, the digital images received today must be translated into analog signals for viewing on today's televisions. Digital video is the final link in the all-digital infrastructure and DLP technoogy provides that link. DLP technology is an enabler for digital, high-resolution, color projection displays that have high contrast, are bright, seamless, and have the accuracy of color and grayscale that can be achieved only by digital control. This paper contains an introduction to DMD and DLP technology, including the historical context from which to view their developemnt. The architecture, projection operation, and fabrication are presented. Finally, the paper includes an update about current DMD business opportunities in projection displays and hardcopy.

SOA-based digital library services and composition in biomedical applications.

PubMed

Zhao, Xia; Liu, Enjie; Clapworthy, Gordon J; Viceconti, Marco; Testi, Debora

2012-06-01

Carefully collected, high-quality data are crucial in biomedical visualization, and it is important that the user community has ready access to both this data and the high-performance computing resources needed by the complex, computational algorithms that will process it. Biological researchers generally require data, tools and algorithms from multiple providers to achieve their goals. This paper illustrates our response to the problems that result from this. The Living Human Digital Library (LHDL) project presented in this paper has taken advantage of Web Services to build a biomedical digital library infrastructure that allows clinicians and researchers not only to preserve, trace and share data resources, but also to collaborate at the data-processing level. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Minimization In Digital Design As A Meta-Planning Problem

NASA Astrophysics Data System (ADS)

Ho, William P. C.; Wu, Jung-Gen

1987-05-01

In our model-based expert system for automatic digital system design, we formalize the design process into three sub-processes - compiling high-level behavioral specifications into primitive behavioral operations, grouping primitive operations into behavioral functions, and grouping functions into modules. Consideration of design minimization explicitly controls decision-making in the last two subprocesses. Design minimization, a key task in the automatic design of digital systems, is complicated by the high degree of interaction among the time sequence and content of design decisions. In this paper, we present an AI approach which directly addresses these interactions and their consequences by modeling the minimization prob-lem as a planning problem, and the management of design decision-making as a meta-planning problem.

Application of a digital data acquisition system for time of flight Positron annihilation-induced Auger Electron Spectroscopy

NASA Astrophysics Data System (ADS)

Gladen, R. W.; Chirayath, V. A.; McDonald, A. D.; Fairchild, A. J.; Chrysler, M. D.; Imam, S. K.; Koymen, A. R.; Weiss, A. H.

We describe herein a digital data acquisition system for a time-of-flight Positron annihilation-induced Auger Electron Spectrometer. This data acquisition system consists of a high-speed digitizer collecting signals induced by Auger electrons and annihilation gammas in a multi-channel plate electron detector and a BaF2 gamma detector, respectively. The time intervals between these two signals is used to determine the times of flight of the Auger electrons, which are analyzed by algorithms based on traditional nuclear electronics methods. Ultimately, this digital data acquisition system will be expanded to incorporate the first coincidence measurements of Auger electron and annihilation gamma energies.

Development of a networked four-million-pixel pathological and radiological digital image presentation system and its application to medical conferences

NASA Astrophysics Data System (ADS)

Sakano, Toshikazu; Furukawa, Isao; Okumura, Akira; Yamaguchi, Takahiro; Fujii, Tetsuro; Ono, Sadayasu; Suzuki, Junji; Matsuya, Shoji; Ishihara, Teruo

2001-08-01

The wide spread of digital technology in the medical field has led to a demand for the high-quality, high-speed, and user-friendly digital image presentation system in the daily medical conferences. To fulfill this demand, we developed a presentation system for radiological and pathological images. It is composed of a super-high-definition (SHD) imaging system, a radiological image database (R-DB), a pathological image database (P-DB), and the network interconnecting these three. The R-DB consists of a 270GB RAID, a database server workstation, and a film digitizer. The P-DB includes an optical microscope, a four-million-pixel digital camera, a 90GB RAID, and a database server workstation. A 100Mbps Ethernet LAN interconnects all the sub-systems. The Web-based system operation software was developed for easy operation. We installed the whole system in NTT East Kanto Hospital to evaluate it in the weekly case conferences. The SHD system could display digital full-color images of 2048 x 2048 pixels on a 28-inch CRT monitor. The doctors evaluated the image quality and size, and found them applicable to the actual medical diagnosis. They also appreciated short image switching time that contributed to smooth presentation. Thus, we confirmed that its characteristics met the requirements.

Superconductor Digital-RF Receiver Systems

NASA Astrophysics Data System (ADS)

Mukhanov, Oleg A.; Kirichenko, Dmitri; Vernik, Igor V.; Filippov, Timur V.; Kirichenko, Alexander; Webber, Robert; Dotsenko, Vladimir; Talalaevskii, Andrei; Tang, Jia Cao; Sahu, Anubhav; Shevchenko, Pavel; Miller, Robert; Kaplan, Steven B.; Sarwana, Saad; Gupta, Deepnarayan

Digital superconductor electronics has been experiencing rapid maturation with the emergence of smaller-scale, lower-cost communications applications which became the major technology drivers. These applications are primarily in the area of wireless communications, radar, and surveillance as well as in imaging and sensor systems. In these areas, the fundamental advantages of superconductivity translate into system benefits through novel Digital-RF architectures with direct digitization of wide band, high frequency radio frequency (RF) signals. At the same time the availability of relatively small 4K cryocoolers has lowered the foremost market barrier for cryogenically-cooled digital electronic systems. Recently, we have achieved a major breakthrough in the development, demonstration, and successful delivery of the cryocooled superconductor digital-RF receivers directly digitizing signals in a broad range from kilohertz to gigahertz. These essentially hybrid-technology systems combine a variety of superconductor and semiconductor technologies packaged with two-stage commercial cryocoolers: cryogenic Nb mixed-signal and digital circuits based on Rapid Single Flux Quantum (RSFQ) technology, room-temperature amplifiers, FPGA processing and control circuitry. The demonstrated cryocooled digital-RF systems are the world's first and fastest directly digitizing receivers operating with live satellite signals in X-band and performing signal acquisition in HF to L-band at ˜30GHz clock frequencies.

A digital-receiver for the MurchisonWidefield Array

NASA Astrophysics Data System (ADS)

Prabu, Thiagaraj; Srivani, K. S.; Roshi, D. Anish; Kamini, P. A.; Madhavi, S.; Emrich, David; Crosse, Brian; Williams, Andrew J.; Waterson, Mark; Deshpande, Avinash A.; Shankar, N. Udaya; Subrahmanyan, Ravi; Briggs, Frank H.; Goeke, Robert F.; Tingay, Steven J.; Johnston-Hollitt, Melanie; R, Gopalakrishna M.; Morgan, Edward H.; Pathikulangara, Joseph; Bunton, John D.; Hampson, Grant; Williams, Christopher; Ord, Stephen M.; Wayth, Randall B.; Kumar, Deepak; Morales, Miguel F.; deSouza, Ludi; Kratzenberg, Eric; Pallot, D.; McWhirter, Russell; Hazelton, Bryna J.; Arcus, Wayne; Barnes, David G.; Bernardi, Gianni; Booler, T.; Bowman, Judd D.; Cappallo, Roger J.; Corey, Brian E.; Greenhill, Lincoln J.; Herne, David; Hewitt, Jacqueline N.; Kaplan, David L.; Kasper, Justin C.; Kincaid, Barton B.; Koenig, Ronald; Lonsdale, Colin J.; Lynch, Mervyn J.; Mitchell, Daniel A.; Oberoi, Divya; Remillard, Ronald A.; Rogers, Alan E.; Salah, Joseph E.; Sault, Robert J.; Stevens, Jamie B.; Tremblay, S.; Webster, Rachel L.; Whitney, Alan R.; Wyithe, Stuart B.

2015-03-01

An FPGA-based digital-receiver has been developed for a low-frequency imaging radio interferometer, the Murchison Widefield Array (MWA). The MWA, located at the Murchison Radio-astronomy Observatory (MRO) in Western Australia, consists of 128 dual-polarized aperture-array elements (tiles) operating between 80 and 300 MHz, with a total processed bandwidth of 30.72 MHz for each polarization. Radio-frequency signals from the tiles are amplified and band limited using analog signal conditioning units; sampled and channelized by digital-receivers. The signals from eight tiles are processed by a single digital-receiver, thus requiring 16 digital-receivers for the MWA. The main function of the digital-receivers is to digitize the broad-band signals from each tile, channelize them to form the sky-band, and transport it through optical fibers to a centrally located correlator for further processing. The digital-receiver firmware also implements functions to measure the signal power, perform power equalization across the band, detect interference-like events, and invoke diagnostic modes. The digital-receiver is controlled by high-level programs running on a single-board-computer. This paper presents the digital-receiver design, implementation, current status, and plans for future enhancements.

Development of a remote digital augmentation system and application to a remotely piloted research vehicle

NASA Technical Reports Server (NTRS)

Edwards, J. W.; Deets, D. A.

1975-01-01

A cost-effective approach to flight testing advanced control concepts with remotely piloted vehicles is described. The approach utilizes a ground based digital computer coupled to the remotely piloted vehicle's motion sensors and control surface actuators through telemetry links to provide high bandwidth feedback control. The system was applied to the control of an unmanned 3/8-scale model of the F-15 airplane. The model was remotely augmented; that is, the F-15 mechanical and control augmentation flight control systems were simulated by the ground-based computer, rather than being in the vehicle itself. The results of flight tests of the model at high angles of attack are discussed.

Digital multi-channel high resolution phase locked loop for surveillance radar systems

NASA Astrophysics Data System (ADS)

Rizk, Mohamed; Shaaban, Shawky; Abou-El-Nadar, Usama M.; Hafez, Alaa El-Din Sayed

This paper present a multi-channel, high resolution, fast lock phase locked loop (PLL) for surveillance radar applications. Phase detector based PLLs are simple to design, suffer no systematic phase error, and can run at the highest speed. Reducing loop gain can proportionally improve jitter performance, but also reduces locking time and pull-in range. The proposed system is based on digital process and control the error signal to the voltage controlled oscillator (VCO) adaptively to control its gain in order to achieve fast lock times while improving in lock jitter performance. Under certain circumstances the design also improves the frequency agility capability of the radar system. The results show a fast lock, high resolution PLL with transient time less than 10 µ sec which is suitable to radar applications.

High-fidelity video and still-image communication based on spectral information: natural vision system and its applications

NASA Astrophysics Data System (ADS)

Yamaguchi, Masahiro; Haneishi, Hideaki; Fukuda, Hiroyuki; Kishimoto, Junko; Kanazawa, Hiroshi; Tsuchida, Masaru; Iwama, Ryo; Ohyama, Nagaaki

2006-01-01

In addition to the great advancement of high-resolution and large-screen imaging technology, the issue of color is now receiving considerable attention as another aspect than the image resolution. It is difficult to reproduce the original color of subject in conventional imaging systems, and that obstructs the applications of visual communication systems in telemedicine, electronic commerce, and digital museum. To breakthrough the limitation of conventional RGB 3-primary systems, "Natural Vision" project aims at an innovative video and still-image communication technology with high-fidelity color reproduction capability, based on spectral information. This paper summarizes the results of NV project including the development of multispectral and multiprimary imaging technologies and the experimental investigations on the applications to medicine, digital archives, electronic commerce, and computer graphics.

Digitally grown AlInAsSb for high gain separate absorption, grading, charge, and multiplication avalanche photodiodes

NASA Astrophysics Data System (ADS)

Lyu, Yuexi; Han, Xi; Sun, Yaoyao; Jiang, Zhi; Guo, Chunyan; Xiang, Wei; Dong, Yinan; Cui, Jie; Yao, Yuan; Jiang, Dongwei; Wang, Guowei; Xu, Yingqiang; Niu, Zhichuan

2018-01-01

We report on the growth of high quality GaSb-based AlInAsSb quaternary alloy by molecular beam epitaxy (MBE) to fabricate avalanche photodiodes (APDs). By means of high resolution X-ray diffraction (HRXRD) and scanning transmission electron microscope (STEM), phase separation phenomenon of AlInAsSb random alloy with naturally occurring vertical superlattice configuration was demonstrated. To overcome the tendency for phase segregation while maintaining a highly crystalline film, a digital alloy technique with migration-enhanced epitaxy growth method was employed, using a shutter sequence of AlSb, AlAs, AlSb, Sb, In, InAs, In, Sb. AlInAsSb digital alloy has proved to be reproducible and consistent with single phase, showing sharp satellite peaks on HRXRD rocking curve and smooth surface morphology under atomic force microscopy (AFM). Using optimized digital alloy, AlInAsSb separate absorption, grading, charge, and multiplication (SAGCM) APD was grown and fabricated. At room temperature, the device showed high performance with low dark current density of ∼14.1 mA/cm2 at 95% breakdown and maximum stable gain before breakdown as high as ∼200, showing the potential for further applications in optoelectronic devices.

Wideband aperture array using RF channelizers and massively parallel digital 2D IIR filterbank

NASA Astrophysics Data System (ADS)

Sengupta, Arindam; Madanayake, Arjuna; Gómez-García, Roberto; Engeberg, Erik D.

2014-05-01

Wideband receive-mode beamforming applications in wireless location, electronically-scanned antennas for radar, RF sensing, microwave imaging and wireless communications require digital aperture arrays that offer a relatively constant far-field beam over several octaves of bandwidth. Several beamforming schemes including the well-known true time-delay and the phased array beamformers have been realized using either finite impulse response (FIR) or fast Fourier transform (FFT) digital filter-sum based techniques. These beamforming algorithms offer the desired selectivity at the cost of a high computational complexity and frequency-dependant far-field array patterns. A novel approach to receiver beamforming is the use of massively parallel 2-D infinite impulse response (IIR) fan filterbanks for the synthesis of relatively frequency independent RF beams at an order of magnitude lower multiplier complexity compared to FFT or FIR filter based conventional algorithms. The 2-D IIR filterbanks demand fast digital processing that can support several octaves of RF bandwidth, fast analog-to-digital converters (ADCs) for RF-to-bits type direct conversion of wideband antenna element signals. Fast digital implementation platforms that can realize high-precision recursive filter structures necessary for real-time beamforming, at RF radio bandwidths, are also desired. We propose a novel technique that combines a passive RF channelizer, multichannel ADC technology, and single-phase massively parallel 2-D IIR digital fan filterbanks, realized at low complexity using FPGA and/or ASIC technology. There exists native support for a larger bandwidth than the maximum clock frequency of the digital implementation technology. We also strive to achieve More-than-Moore throughput by processing a wideband RF signal having content with N-fold (B = N Fclk/2) bandwidth compared to the maximum clock frequency Fclk Hz of the digital VLSI platform under consideration. Such increase in bandwidth is achieved without use of polyphase signal processing or time-interleaved ADC methods. That is, all digital processors operate at the same Fclk clock frequency without phasing, while wideband operation is achieved by sub-sampling of narrower sub-bands at the the RF channelizer outputs.

Application research for 4D technology in flood forecasting and evaluation

NASA Astrophysics Data System (ADS)

Li, Ziwei; Liu, Yutong; Cao, Hongjie

1998-08-01

In order to monitor the region which disaster flood happened frequently in China, satisfy the great need of province governments for high accuracy monitoring and evaluated data for disaster and improve the efficiency for repelling disaster, under the Ninth Five-year National Key Technologies Programme, the method was researched for flood forecasting and evaluation using satellite and aerial remoted sensed image and land monitor data. The effective and practicable flood forecasting and evaluation system was established and DongTing Lake was selected as the test site. Modern Digital photogrammetry, remote sensing and GIS technology was used in this system, the disastrous flood could be forecasted and loss can be evaluated base on '4D' (DEM -- Digital Elevation Model, DOQ -- Digital OrthophotoQuads, DRG -- Digital Raster Graph, DTI -- Digital Thematic Information) disaster background database. The technology of gathering and establishing method for '4D' disaster environment background database, application technology for flood forecasting and evaluation based on '4D' background data and experimental results for DongTing Lake test site were introduced in detail in this paper.

Concierge: Personal Database Software for Managing Digital Research Resources

PubMed Central

Sakai, Hiroyuki; Aoyama, Toshihiro; Yamaji, Kazutsuna; Usui, Shiro

2007-01-01

This article introduces a desktop application, named Concierge, for managing personal digital research resources. Using simple operations, it enables storage of various types of files and indexes them based on content descriptions. A key feature of the software is a high level of extensibility. By installing optional plug-ins, users can customize and extend the usability of the software based on their needs. In this paper, we also introduce a few optional plug-ins: literature management, electronic laboratory notebook, and XooNlps client plug-ins. XooNIps is a content management system developed to share digital research resources among neuroscience communities. It has been adopted as the standard database system in Japanese neuroinformatics projects. Concierge, therefore, offers comprehensive support from management of personal digital research resources to their sharing in open-access neuroinformatics databases such as XooNIps. This interaction between personal and open-access neuroinformatics databases is expected to enhance the dissemination of digital research resources. Concierge is developed as an open source project; Mac OS X and Windows XP versions have been released at the official site (http://concierge.sourceforge.jp). PMID:18974800

Electronic health record meets digital library: a new environment for achieving an old goal.

PubMed

Humphreys, B L

2000-01-01

Linking the electronic health record to the digital library is a Web-era reformulation of the long-standing informatics goal of seamless integration of automated clinical data and relevant knowledge-based information to support informed decisions. The spread of the Internet, the development of the World Wide Web, and converging format standards for electronic health data and digital publications make effective linking increasingly feasible. Some existing systems link electronic health data and knowledge-based information in limited settings or limited ways. Yet many challenging informatics research problems remain to be solved before flexible and seamless linking becomes a reality and before systems become capable of delivering the specific piece of information needed at the time and place a decision must be made. Connecting the electronic health record to the digital library also requires positive resolution of important policy issues, including health data privacy, government encouragement of high-speed communications, electronic intellectual property rights, and standards for health data and for digital libraries. Both the research problems and the policy issues should be important priorities for the field of medical informatics.

Electronic Health Record Meets Digital Library

PubMed Central

Humphreys, Betsy L.

2000-01-01

Linking the electronic health record to the digital library is a Web-era reformulation of the long-standing informatics goal of seamless integration of automated clinical data and relevant knowledge-based information to support informed decisions. The spread of the Internet, the development of the World Wide Web, and converging format standards for electronic health data and digital publications make effective linking increasingly feasible. Some existing systems link electronic health data and knowledge-based information in limited settings or limited ways. Yet many challenging informatics research problems remain to be solved before flexible and seamless linking becomes a reality and before systems become capable of delivering the specific piece of information needed at the time and place a decision must be made. Connecting the electronic health record to the digital library also requires positive resolution of important policy issues, including health data privacy, government envouragement of high-speed communications, electronic intellectual property rights, and standards for health data and for digital libraries. Both the research problems and the policy issues should be important priorities for the field of medical informatics. PMID:10984463

Design and implementation of a reconfigurable mixed-signal SoC based on field programmable analog arrays

NASA Astrophysics Data System (ADS)

Liu, Lintao; Gao, Yuhan; Deng, Jun

2017-11-01

This work presents a reconfigurable mixed-signal system-on-chip (SoC), which integrates switched-capacitor-based field programmable analog arrays (FPAA), analog-to-digital converter (ADC), digital-to-analog converter, digital down converter , digital up converter, 32-bit reduced instruction-set computer central processing unit (CPU) and other digital IPs on a single chip with 0.18 μm CMOS technology. The FPAA intellectual property could be reconfigured as different function circuits, such as gain amplifier, divider, sine generator, and so on. This single-chip integrated mixed-signal system is a complete modern signal processing system, occupying a die area of 7 × 8 mm 2 and consuming 719 mW with a clock frequency of 150 MHz for CPU and 200 MHz for ADC/DAC. This SoC chip can help customers to shorten design cycles, save board area, reduce the system power consumption and depress the system integration risk, which would afford a big prospect of application for wireless communication. Project supported by the National High Technology and Development Program of China (No. 2012AA012303).

Design and theoretical investigation of a digital x-ray detector with large area and high spatial resolution

NASA Astrophysics Data System (ADS)

Gui, Jianbao; Guo, Jinchuan; Yang, Qinlao; Liu, Xin; Niu, Hanben

2007-05-01

X-ray phase contrast imaging is a promising new technology today, but the requirements of a digital detector with large area, high spatial resolution and high sensitivity bring forward a large challenge to researchers. This paper is related to the design and theoretical investigation of an x-ray direct conversion digital detector based on mercuric iodide photoconductive layer with the latent charge image readout by photoinduced discharge (PID). Mercuric iodide has been verified having a good imaging performance (high sensitivity, low dark current, low voltage operation and good lag characteristics) compared with the other competitive materials (α-Se,PbI II,CdTe,CdZnTe) and can be easily deposited on large substrates in the manner of polycrystalline. By use of line scanning laser beam and parallel multi-electrode readout make the system have high spatial resolution and fast readout speed suitable for instant general radiography and even rapid sequence radiography.

Investigation of Portevin-Le Chatelier effect in 5456 Al-based alloy using digital image correlation

NASA Astrophysics Data System (ADS)

Cheng, Teng; Xu, Xiaohai; Cai, Yulong; Fu, Shihua; Gao, Yue; Su, Yong; Zhang, Yong; Zhang, Qingchuan

2015-02-01

A variety of experimental methods have been proposed for Portevin-Le Chatelier (PLC) effect. They mainly focused on the in-plane deformation. In order to achieve the high-accuracy measurement, three-dimensional digital image correlation (3D-DIC) was employed in this work to investigate the PLC effect in 5456 Al-based alloy. The temporal and spatial evolutions of deformation in the full field of specimen surface were observed. The large deformation of localized necking was determined experimentally. The distributions of out-of-plane displacement over the loading procedure were also obtained. Furthermore, a comparison of measurement accuracy between two-dimensional digital image correlation (2D-DIC) and 3D-DIC was also performed. Due to the theoretical restriction, the measurement accuracy of 2D-DIC decreases with the increase of deformation. A maximum discrepancy of about 20% with 3D-DIC was observed in this work. Therefore, 3D-DIC is actually more essential for the high-accuracy investigation of PLC effect.

Determination of high temperature strains using a PC based vision system

NASA Astrophysics Data System (ADS)

McNeill, Stephen R.; Sutton, Michael A.; Russell, Samuel S.

1992-09-01

With the widespread availability of video digitizers and cheap personal computers, the use of computer vision as an experimental tool is becoming common place. These systems are being used to make a wide variety of measurements that range from simple surface characterization to velocity profiles. The Sub-Pixel Digital Image Correlation technique has been developed to measure full field displacement and gradients of the surface of an object subjected to a driving force. The technique has shown its utility by measuring the deformation and movement of objects that range from simple translation to fluid velocity profiles to crack tip deformation of solid rocket fuel. This technique has recently been improved and used to measure the surface displacement field of an object at high temperature. The development of a PC based Sub-Pixel Digital Image Correlation system has yielded an accurate and easy to use system for measuring surface displacements and gradients. Experiments have been performed to show the system is viable for measuring thermal strain.

Off-axis digital holographic camera for quantitative phase microscopy.

PubMed

Monemhaghdoust, Zahra; Montfort, Frédéric; Emery, Yves; Depeursinge, Christian; Moser, Christophe

2014-06-01

We propose and experimentally demonstrate a digital holographic camera which can be attached to the camera port of a conventional microscope for obtaining digital holograms in a self-reference configuration, under short coherence illumination and in a single shot. A thick holographic grating filters the beam containing the sample information in two dimensions through diffraction. The filtered beam creates the reference arm of the interferometer. The spatial filtering method, based on the high angular selectivity of the thick grating, reduces the alignment sensitivity to angular displacements compared with pinhole based Fourier filtering. The addition of a thin holographic grating alters the coherence plane tilt introduced by the thick grating so as to create high-visibility interference over the entire field of view. The acquired full-field off-axis holograms are processed to retrieve the amplitude and phase information of the sample. The system produces phase images of cheek cells qualitatively similar to phase images extracted with a standard commercial DHM.

Development of Armenian-Georgian Virtual Observatory

NASA Astrophysics Data System (ADS)

Mickaelian, Areg; Kochiashvili, Nino; Astsatryan, Hrach; Harutyunian, Haik; Magakyan, Tigran; Chargeishvili, Ketevan; Natsvlishvili, Rezo; Kukhianidze, Vasil; Ramishvili, Giorgi; Sargsyan, Lusine; Sinamyan, Parandzem; Kochiashvili, Ia; Mikayelyan, Gor

2009-10-01

The Armenian-Georgian Virtual Observatory (ArGVO) project is the first initiative in the world to create a regional VO infrastructure based on national VO projects and regional Grid. The Byurakan and Abastumani Astrophysical Observatories are scientific partners since 1946, after establishment of the Byurakan observatory . The Armenian VO project (ArVO) is being developed since 2005 and is a part of the International Virtual Observatory Alliance (IVOA). It is based on the Digitized First Byurakan Survey (DFBS, the digitized version of famous Markarian survey) and other Armenian archival data. Similarly, the Georgian VO will be created to serve as a research environment to utilize the digitized Georgian plate archives. Therefore, one of the main goals for creation of the regional VO is the digitization of large amounts of plates preserved at the plate stacks of these two observatories. The total amount of plates is more than 100,000 units. Observational programs of high importance have been selected and some 3000 plates will be digitized during the next two years; the priority is being defined by the usefulness of the material for future science projects, like search for new objects, optical identifications of radio, IR, and X-ray sources, study of variability and proper motions, etc. Having the digitized material in VO standards, a VO database through the regional Grid infrastructure will be active. This partnership is being carried out in the framework of the ISTC project A-1606 "Development of Armenian-Georgian Grid Infrastructure and Applications in the Fields of High Energy Physics, Astrophysics and Quantum Physics".

Towards machine learned quality control: A benchmark for sharpness quantification in digital pathology.

PubMed

Campanella, Gabriele; Rajanna, Arjun R; Corsale, Lorraine; Schüffler, Peter J; Yagi, Yukako; Fuchs, Thomas J

2018-04-01

Pathology is on the verge of a profound change from an analog and qualitative to a digital and quantitative discipline. This change is mostly driven by the high-throughput scanning of microscope slides in modern pathology departments, reaching tens of thousands of digital slides per month. The resulting vast digital archives form the basis of clinical use in digital pathology and allow large scale machine learning in computational pathology. One of the most crucial bottlenecks of high-throughput scanning is quality control (QC). Currently, digital slides are screened manually to detected out-of-focus regions, to compensate for the limitations of scanner software. We present a solution to this problem by introducing a benchmark dataset for blur detection, an in-depth comparison of state-of-the art sharpness descriptors and their prediction performance within a random forest framework. Furthermore, we show that convolution neural networks, like residual networks, can be used to train blur detectors from scratch. We thoroughly evaluate the accuracy of feature based and deep learning based approaches for sharpness classification (99.74% accuracy) and regression (MSE 0.004) and additionally compare them to domain experts in a comprehensive human perception study. Our pipeline outputs spacial heatmaps enabling to quantify and localize blurred areas on a slide. Finally, we tested the proposed framework in the clinical setting and demonstrate superior performance over the state-of-the-art QC pipeline comprising commercial software and human expert inspection by reducing the error rate from 17% to 4.7%. Copyright © 2017. Published by Elsevier Ltd.

A high-speed network for cardiac image review.

PubMed

Elion, J L; Petrocelli, R R

1994-01-01

A high-speed fiber-based network for the transmission and display of digitized full-motion cardiac images has been developed. Based on Asynchronous Transfer Mode (ATM), the network is scaleable, meaning that the same software and hardware is used for a small local area network or for a large multi-institutional network. The system can handle uncompressed digital angiographic images, considered to be at the "high-end" of the bandwidth requirements. Along with the networking, a general-purpose multi-modality review station has been implemented without specialized hardware. This station can store a full injection sequence in "loop RAM" in a 512 x 512 format, then interpolate to 1024 x 1024 while displaying at 30 frames per second. The network and review stations connect to a central file server that uses a virtual file system to make a large high-speed RAID storage disk and associated off-line storage tapes and cartridges all appear as a single large file system to the software. In addition to supporting archival storage and review, the system can also digitize live video using high-speed Direct Memory Access (DMA) from the frame grabber to present uncompressed data to the network. Fully functional prototypes have provided the proof of concept, with full deployment in the institution planned as the next stage.

A high-speed network for cardiac image review.

PubMed Central

Elion, J. L.; Petrocelli, R. R.

1994-01-01

A high-speed fiber-based network for the transmission and display of digitized full-motion cardiac images has been developed. Based on Asynchronous Transfer Mode (ATM), the network is scaleable, meaning that the same software and hardware is used for a small local area network or for a large multi-institutional network. The system can handle uncompressed digital angiographic images, considered to be at the "high-end" of the bandwidth requirements. Along with the networking, a general-purpose multi-modality review station has been implemented without specialized hardware. This station can store a full injection sequence in "loop RAM" in a 512 x 512 format, then interpolate to 1024 x 1024 while displaying at 30 frames per second. The network and review stations connect to a central file server that uses a virtual file system to make a large high-speed RAID storage disk and associated off-line storage tapes and cartridges all appear as a single large file system to the software. In addition to supporting archival storage and review, the system can also digitize live video using high-speed Direct Memory Access (DMA) from the frame grabber to present uncompressed data to the network. Fully functional prototypes have provided the proof of concept, with full deployment in the institution planned as the next stage. PMID:7949964

Design of DSP-based high-power digital solar array simulator

NASA Astrophysics Data System (ADS)

Zhang, Yang; Liu, Zhilong; Tong, Weichao; Feng, Jian; Ji, Yibo

2013-12-01

To satisfy rigid performance specifications, a feedback control was presented for zoom optical lens plants. With the increasing of global energy consumption, research of the photovoltaic(PV) systems get more and more attention. Research of the digital high-power solar array simulator provides technical support for high-power grid-connected PV systems research.This paper introduces a design scheme of the high-power digital solar array simulator based on TMS320F28335. A DC-DC full-bridge topology was used in the system's main circuit. The switching frequency of IGBT is 25kHz.Maximum output voltage is 900V. Maximum output current is 20A. Simulator can be pre-stored solar panel IV curves.The curve is composed of 128 discrete points .When the system was running, the main circuit voltage and current values was feedback to the DSP by the voltage and current sensors in real-time. Through incremental PI,DSP control the simulator in the closed-loop control system. Experimental data show that Simulator output voltage and current follow a preset solar panels IV curve. In connection with the formation of high-power inverter, the system becomes gridconnected PV system. The inverter can find the simulator's maximum power point and the output power can be stabilized at the maximum power point (MPP).

FPGA-based digital signal processing for the next generation radio astronomy instruments: ultra-pure sideband separation and polarization detection

NASA Astrophysics Data System (ADS)

Alvear, Andrés.; Finger, Ricardo; Fuentes, Roberto; Sapunar, Raúl; Geelen, Tom; Curotto, Franco; Rodríguez, Rafael; Monasterio, David; Reyes, Nicolás.; Mena, Patricio; Bronfman, Leonardo

2016-07-01

Field Programmable Gate Arrays (FPGAs) capacity and Analog to Digital Converters (ADCs) speed have largely increased in the last decade. Nowadays we can find one million or more logic blocks (slices) as well as several thousand arithmetic units (ALUs/DSP) available on a single FPGA chip. We can also commercially procure ADC chips reaching 10 GSPS, with 8 bits resolution or more. This unprecedented power of computing hardware has allowed the digitalization of signal processes traditionally performed by analog components. In radio astronomy, the clearest example has been the development of digital sideband separating receivers which, by replacing the IF hybrid and calibrating the system imbalances, have exhibited a sideband rejection above 40dB; this is 20 to 30dB higher than traditional analog sideband separating (2SB) receivers. In Rodriguez et al.,1 and Finger et al.,2 we have demonstrated very high digital sideband separation at 3mm and 1mm wavelengths, using laboratory setups. We here show the first implementation of such technique with a 3mm receiver integrated into a telescope, where the calibration was performed by quasi-optical injection of the test tone in front of the Cassegrain antenna. We also reported progress in digital polarization synthesis, particularly in the implementation of a calibrated Digital Ortho-Mode Transducer (DOMT) based on the Morgan et al. proof of concept.3 They showed off- line synthesis of polarization with isolation higher than 40dB. We plan to implement a digital polarimeter in a real-time FPGA-based (ROACH-2) platform, to show ultra-pure polarization isolation in a non-stop integrating spectrometer.

Performance of high-temperature superconducting band-pass filters with high selectivity for base transceiver applications of digital cellular communication systems

NASA Astrophysics Data System (ADS)

Kwak, J. S.; Lee, J. H.; Kim, C. O.; Hong, J. P.; Han, S. K.; Char, K.

2002-07-01

Highly selective high-temperature superconducting band-pass filters based on spiral meander line structures have been developed for base transceiver station applications of digital cellular communication systems. The filter comprised 12-pole microstrip line resonators with a circuit size of 0.5 × 17 × 41 mm3. The filter was designed to have a bandwidth of 25 MHz at a centre frequency of 834 MHz. Particularly, the physical size of each resonator was chosen not only to reduce far-field radiation, but also to have reasonable tunability in the filter. Device characteristics exhibited a low insertion loss of 0.4 dB with a 0.2 dB ripple and a return loss better than 10 dB in the pass-band at 65 K. The out-of-band signals were attenuated better than 60 dB at about 3.5 MHz from the lower band edge, and 3.8 MHz from the higher band edge.

N channel JFET based digital logic gate structure

NASA Technical Reports Server (NTRS)

Krasowski, Michael J. (Inventor)

2010-01-01

A circuit topography is presented which is used to create usable digital logic gates using N (negatively doped) channel Junction Field Effect Transistors (JFETs) and load resistors, level shifting resistors, and supply rails whose values are based on the direct current (DC) parametric distributions of those JFETs. This method has direct application to the current state of the art in high temperature, for example 300.degree. C. to 500.degree. C. and higher, silicon carbide (SiC) device production. The ability to produce inverting and combinatorial logic enables the production of pulse and edge triggered latches. This scale of logic synthesis would bring digital logic and state machine capabilities to devices operating in extremely hot environments, such as the surface of Venus, near hydrothermal vents, within nuclear reactors (SiC is inherently radiation hardened), and within internal combustion engines. The basic logic gate can be configured as a driver for oscillator circuits allowing for time bases and simple digitizers for resistive or reactive sensors. The basic structure of this innovation, the inverter, can be reconfigured into various analog circuit topographies through the use of feedback structures.

The potential for neurovascular intravenous angiography using K-edge digital subtraction angiography

NASA Astrophysics Data System (ADS)

Schültke, E.; Fiedler, S.; Kelly, M.; Griebel, R.; Juurlink, B.; LeDuc, G.; Estève, F.; Le Bas, J.-F.; Renier, M.; Nemoz, C.; Meguro, K.

2005-08-01

Background: Catheterization of small-caliber blood vessels in the central nervous system can be extremely challenging. Alternatively, intravenous (i.v.) administration of contrast agent is minimally invasive and therefore carries a much lower risk for the patient. With conventional X-ray equipment, volumes of contrast agent that could be safely administered to the patient do not allow acquisition of high-quality images after i.v. injection, because the contrast bolus is extremely diluted by passage through the heart. However, synchrotron-based digital K-edge subtraction angiography does allow acquisition of high-quality images after i.v. administration of relatively small doses of contrast agent. Materials and methods: Eight adult male New Zealand rabbits were used for our experiments. Animals were submitted to both angiography with conventional X-ray equipment and synchrotron-based digital subtraction angiography. Results: With conventional X-ray equipment, no contrast was seen in either cerebral or spinal blood vessels after i.v. injection of iodinated contrast agent. However, using K-edge digital subtraction angiography, as little as 1 ml iodinated contrast agent, when administered as i.v. bolus, yielded images of small-caliber blood vessels in the central nervous system (both brain and spinal cord). Conclusions: If it would be possible to image blood vessels of the same diameter in the central nervous system of human patients, the synchrotron-based technique could yield high-quality images at a significantly lower risk for the patient than conventional X-ray imaging. Images could be acquired where catheterization of feeding blood vessels has proven impossible.

Absolute quantification of DNA methylation using microfluidic chip-based digital PCR.

PubMed

Wu, Zhenhua; Bai, Yanan; Cheng, Zule; Liu, Fangming; Wang, Ping; Yang, Dawei; Li, Gang; Jin, Qinghui; Mao, Hongju; Zhao, Jianlong

2017-10-15

Hypermethylation of CpG islands in the promoter region of many tumor suppressor genes downregulates their expression and in a result promotes tumorigenesis. Therefore, detection of DNA methylation status is a convenient diagnostic tool for cancer detection. Here, we reported a novel method for the integrative detection of methylation by the microfluidic chip-based digital PCR. This method relies on methylation-sensitive restriction enzyme HpaII, which cleaves the unmethylated DNA strands while keeping the methylated ones intact. After HpaII treatment, the DNA methylation level is determined quantitatively by the microfluidic chip-based digital PCR with the lower limit of detection equal to 0.52%. To validate the applicability of this method, promoter methylation of two tumor suppressor genes (PCDHGB6 and HOXA9) was tested in 10 samples of early stage lung adenocarcinoma and their adjacent non-tumorous tissues. The consistency was observed in the analysis of these samples using our method and a conventional bisulfite pyrosequencing. Combining high sensitivity and low cost, the microfluidic chip-based digital PCR method might provide a promising alternative for the detection of DNA methylation and early diagnosis of epigenetics-related diseases. Copyright © 2017 Elsevier B.V. All rights reserved.

Design and image-quality performance of high resolution CMOS-based X-ray imaging detectors for digital mammography

NASA Astrophysics Data System (ADS)

Cha, B. K.; Kim, J. Y.; Kim, Y. J.; Yun, S.; Cho, G.; Kim, H. K.; Seo, C.-W.; Jeon, S.; Huh, Y.

2012-04-01

In digital X-ray imaging systems, X-ray imaging detectors based on scintillating screens with electronic devices such as charge-coupled devices (CCDs), thin-film transistors (TFT), complementary metal oxide semiconductor (CMOS) flat panel imagers have been introduced for general radiography, dental, mammography and non-destructive testing (NDT) applications. Recently, a large-area CMOS active-pixel sensor (APS) in combination with scintillation films has been widely used in a variety of digital X-ray imaging applications. We employed a scintillator-based CMOS APS image sensor for high-resolution mammography. In this work, both powder-type Gd2O2S:Tb and a columnar structured CsI:Tl scintillation screens with various thicknesses were fabricated and used as materials to convert X-ray into visible light. These scintillating screens were directly coupled to a CMOS flat panel imager with a 25 × 50 mm2 active area and a 48 μm pixel pitch for high spatial resolution acquisition. We used a W/Al mammographic X-ray source with a 30 kVp energy condition. The imaging characterization of the X-ray detector was measured and analyzed in terms of linearity in incident X-ray dose, modulation transfer function (MTF), noise-power spectrum (NPS) and detective quantum efficiency (DQE).

The Effects of Online Interactive Games on High School Students' Achievement and Motivation in History Learning

ERIC Educational Resources Information Center

Lin, Kuan-Cheng; Wei, Yu Che; Hung, Jason C.

2012-01-01

Many studies demonstrate that Digital Game Based Learning (DGBL) can foster learning effect. The purpose of this study is to survey whether the online game in junior high school students can encourage learning effect in Taiwan's History. So, the research applied Interactive Game-based Learning System (IGLS) to junior high history teaching as an…

User Language Specification

DTIC Science & Technology

1977-06-30

Digital System Design based on Structural and Function Modeling. Computer Science Dept., UCLA, (UCLA-ENG-7488), 1975. [7] Hamlet, R. G. High-level...of libaries of pro- grams where each library represents a coherent set of data types and parameterized nodes which operate on those types. * Allow...following form: an optional minus sign, concatenated with an optional sequence of digits the first of which is nonzero, concatenated with a single

Learning to Engage: How Positive Attitudes about the News, Media Literacy, and Video Production Contribute to Adolescent Civic Engagement

ERIC Educational Resources Information Center

Hobbs, Renee; Donnelly, Katie; Friesem, Jonathan; Moen, Mary

2013-01-01

Many students enroll in video production courses in high school as part of a vocational, career, or technical program. While there has been an explosion of scholarly work in digital literacy in informal settings, less is known about how digital and media literacy competencies are developed through school-based video production courses. This study…

Mapping Vegetation Community Types in a Highly-Disturbed Landscape: Integrating Hiearchical Object-Based Image Analysis with Digital Surface Models

NASA Astrophysics Data System (ADS)

Snavely, Rachel A.

Focusing on the semi-arid and highly disturbed landscape of San Clemente Island, California, this research tests the effectiveness of incorporating a hierarchal object-based image analysis (OBIA) approach with high-spatial resolution imagery and light detection and range (LiDAR) derived canopy height surfaces for mapping vegetation communities. The study is part of a large-scale research effort conducted by researchers at San Diego State University's (SDSU) Center for Earth Systems Analysis Research (CESAR) and Soil Ecology and Restoration Group (SERG), to develop an updated vegetation community map which will support both conservation and management decisions on Naval Auxiliary Landing Field (NALF) San Clemente Island. Trimble's eCognition Developer software was used to develop and generate vegetation community maps for two study sites, with and without vegetation height data as input. Overall and class-specific accuracies were calculated and compared across the two classifications. The highest overall accuracy (approximately 80%) was observed with the classification integrating airborne visible and near infrared imagery having very high spatial resolution with a LiDAR derived canopy height model. Accuracies for individual vegetation classes differed between both classification methods, but were highest when incorporating the LiDAR digital surface data. The addition of a canopy height model, however, yielded little difference in classification accuracies for areas of very dense shrub cover. Overall, the results show the utility of the OBIA approach for mapping vegetation with high spatial resolution imagery, and emphasizes the advantage of both multi-scale analysis and digital surface data for accuracy characterizing highly disturbed landscapes. The integrated imagery and digital canopy height model approach presented both advantages and limitations, which have to be considered prior to its operational use in mapping vegetation communities.

A Comparison of Strategies for Retinopathy of Prematurity Detection

PubMed Central

Prosser, Lisa A.; Wade, Kelly C.; Repka, Michael X.; Ying, Gui-shuang; Baumritter, Agnieshka; Quinn, Graham E.

2016-01-01

BACKGROUND AND OBJECTIVES: Delayed detection of type 1 retinopathy of prematurity (ROP) can lead to permanent visual impairment. Providing ROP examinations is challenging because of the limited ophthalmology workforce. This study compares digital imaging–based ROP detection strategies versus serial ROP examinations. METHODS: We conducted an individual-level microsimulation studyof a hypothetical cohort of 650 infants with gestational age from 23 to 30 weeks. Infants were evaluated by using strategies based on indirect ophthalmoscopy or digital imaging beginning at 32 weeks’ postmenstrual age (PMA) and continuing to discharge, transfer, or 40 weeks’ PMA. ROP status and the accuracy of digital imaging were based on the e-ROP (Telemedicine Approaches to Evaluating Acute-Phase ROP) study, which enrolled high-risk infants. RESULTS: Within the hypothetical NICU, the strategy of ROP examinations identified an average of 45.8 cases of type 1 ROP by discharge, transfer, or 40 weeks’ PMA, and another 1.9 cases were included in the group of infants recommended to have later follow-up. Digital imaging with an ROP examination at discharge identified all 47.7 cases of type 1 ROP. On average, the ROP examination–only strategy required 1745.7 ROP examinations, whereas digital imaging with a discharge examination required 1065.5 ROP examinations and 1786.2 digital imaging sessions. CONCLUSIONS: Although digital imaging decreased the number of ROP examinations per infant, there was an increase in the total number of interventions (ie, ROP examinations and imaging sessions). Providing an ROP examination at the time of NICU discharge can significantly reduce the number of infants who require follow-up. PMID:26672022

A COMPARISON OF ILLUMINATION GEOMETRY-BASED METHODS FOR TOPOGRAPHIC CORRECTION OF QUICKBIRD IMAGES OF AN UNDULANT AREA

USDA-ARS?s Scientific Manuscript database

The high spatial resolution of QuickBird satellite images makes it possible to show spatial variability at fine details. However, the effect of topography-induced illumination variations become more evident, even in moderately sloped areas. Based on a high resolution (1 m) digital elevation model ge...

Fast digital zooming system using directionally adaptive image interpolation and restoration.

PubMed

Kang, Wonseok; Jeon, Jaehwan; Yu, Soohwan; Paik, Joonki

2014-01-01

This paper presents a fast digital zooming system for mobile consumer cameras using directionally adaptive image interpolation and restoration methods. The proposed interpolation algorithm performs edge refinement along the initially estimated edge orientation using directionally steerable filters. Either the directionally weighted linear or adaptive cubic-spline interpolation filter is then selectively used according to the refined edge orientation for removing jagged artifacts in the slanted edge region. A novel image restoration algorithm is also presented for removing blurring artifacts caused by the linear or cubic-spline interpolation using the directionally adaptive truncated constrained least squares (TCLS) filter. Both proposed steerable filter-based interpolation and the TCLS-based restoration filters have a finite impulse response (FIR) structure for real time processing in an image signal processing (ISP) chain. Experimental results show that the proposed digital zooming system provides high-quality magnified images with FIR filter-based fast computational structure.

3D Digital Surveying and Modelling of Cave Geometry: Application to Paleolithic Rock Art

PubMed Central

González-Aguilera, Diego; Muñoz-Nieto, Angel; Gómez-Lahoz, Javier; Herrero-Pascual, Jesus; Gutierrez-Alonso, Gabriel

2009-01-01

3D digital surveying and modelling of cave geometry represents a relevant approach for research, management and preservation of our cultural and geological legacy. In this paper, a multi-sensor approach based on a terrestrial laser scanner, a high-resolution digital camera and a total station is presented. Two emblematic caves of Paleolithic human occupation and situated in northern Spain, “Las Caldas” and “Peña de Candamo”, have been chosen to put in practise this approach. As a result, an integral and multi-scalable 3D model is generated which may allow other scientists, pre-historians, geologists…, to work on two different levels, integrating different Paleolithic Art datasets: (1) a basic level based on the accurate and metric support provided by the laser scanner; and (2) a advanced level using the range and image-based modelling. PMID:22399958

Digital Radiography Qualification of Tube Welding

NASA Technical Reports Server (NTRS)

Carl, Chad

2012-01-01

The Orion Project will be directing Lockheed Martin to perform orbital arc welding on commodities metallic tubing as part of the Multi Purpose Crew Vehicle assembly and integration process in the Operations and Checkout High bay at Kennedy Space Center. The current method of nondestructive evaluation is utilizing traditional film based x-rays. Due to the high number of welds that are necessary to join the commodities tubing (approx 470), a more efficient and expeditious method of nondestructive evaluation is desired. Digital radiography will be qualified as part of a broader NNWG project scope.

BENEFITS OF TOTAL BODY PHOTOGRAPHY AND DIGITAL DERMOSCOPY (“TWO-STEP METHOD OF DIGITAL FOLLOW-UP”) IN THE EARLY DIAGNOSIS OF MELANOMA IN HIGH-RISK PATIENTS

PubMed Central

Salerni, Gabriel; Carrera, Cristina; Lovatto, Louise; Puig-Butille, Joan Anton; Badenas, Celia; Plana, Estel; Puig, Susana; Malvehy, Josep

2011-01-01

Background Early detection of melanoma is the best way to improve prognosis. Digital follow up (DFU) programs of high-risk populations could be an efficient strategy for detecting early melanomas with low morbidity. Objective to report the added value of the use of the “two-step method” (digital total-body photography and digital dermoscopy) Methods Analysis of the surveillance of 618 high-risk melanoma patients included in our DFU-program from 1999 to 2008. Results A total of 11396 lesions were monitored (mean 18.44 per patient) during a median follow-up of 96 months (median 10 visits per patient). 1152 lesions, 1.86 per patient, were excised. Almost 70% (798) were lesions previously registered at least twice, while 356 (30%) were detected and removed in the same visit. During follow-up, 98 melanomas (8.5% of excised lesions) were diagnosed in 78 patients (12.6%). 53 melanomas were in situ (53.3%), while invasive (45) showed a Breslow index of less than 1 mm (median 0.5 mm) and none was ulcerated. Limitations Since there are no control groups we cannot convey if the combined use of total-body photography and digital dermoscopy is more beneficial than these techniques used separately. Conclusion DFU with Total-Body Photography and Dermoscopy in a selected high-risk population demonstrated the early detection of melanomas with a low rate of excisions. Long-term follow-up is required to allow the detection of slow growing melanomas. Based on our 10-year experience, melanomas can be diagnosed at any time, suggesting that in high-risk population, DFU should be maintained with time. PMID:21683472

Design, Simulation and Characteristics Research of the Interface Circuit based on nano-polysilicon thin films pressure sensor

NASA Astrophysics Data System (ADS)

Zhao, Xiaosong; Zhao, Xiaofeng; Yin, Liang

2018-03-01

This paper presents a interface circuit for nano-polysilicon thin films pressure sensor. The interface circuit includes consist of instrument amplifier and Analog-to-Digital converter (ADC). The instrumentation amplifier with a high common mode rejection ratio (CMRR) is implemented by three stages current feedback structure. At the same time, in order to satisfy the high precision requirements of pressure sensor measure system, the 1/f noise corner of 26.5 mHz can be achieved through chopping technology at a noise density of 38.2 nV/sqrt(Hz).Ripple introduced by chopping technology adopt continuous ripple reduce circuit (RRL), which achieves the output ripple level is lower than noise. The ADC achieves 16 bits significant digit by adopting sigma-delta modulator with fourth-order single-bit structure and digital decimation filter, and finally achieves high precision integrated pressure sensor interface circuit.

Individual left-hand and right-hand intra-digit representations in human primary somatosensory cortex.

PubMed

Schweisfurth, Meike A; Frahm, Jens; Schweizer, Renate

2015-09-01

Individual intra-digit somatotopy of all phalanges of the middle and little finger of the right and left hand was studied by functional magnetic resonance imaging in 12 healthy subjects. Phalanges were tactilely stimulated and activation in BA 3b of the human primary somatosensory cortex could be observed for each individual phalanx. Activation peaks were further analysed using the Direction/Order (DiOr) method, which identifies somatotopy, if a significantly high number of subjects exhibit ordered distal-to-proximal phalanx representions along a similar direction. Based on DiOr, ordered and similar-direction-aligned intra-digit maps across subjects were found at the left hand for the little and middle finger and at the right hand for the little finger. In these digits the proximal phalanges were represented more medially along the course of the central sulcus than the distal phalanges. This is contrasted by the intra-digit maps for the middle finger of the right hand, which showed larger inter-subject variations of phalanx alignments without a similar within-digit representation across subjects. As all subjects were right-handed and as the middle finger of the dominant hand probably plays a more individual role in everyday tactile performance than the little finger of the right hand and all left-hand digits, the observed variation might reflect a functional somatotopy based on individual use of that particular digit at the dominant hand. © 2015 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Resolution analysis of archive films for the purpose of their optimal digitization and distribution

NASA Astrophysics Data System (ADS)

Fliegel, Karel; Vítek, Stanislav; Páta, Petr; Myslík, Jiří; Pecák, Josef; Jícha, Marek

2017-09-01

With recent high demand for ultra-high-definition (UHD) content to be screened in high-end digital movie theaters but also in the home environment, film archives full of movies in high-definition and above are in the scope of UHD content providers. Movies captured with the traditional film technology represent a virtually unlimited source of UHD content. The goal to maintain complete image information is also related to the choice of scanning resolution and spatial resolution for further distribution. It might seem that scanning the film material in the highest possible resolution using state-of-the-art film scanners and also its distribution in this resolution is the right choice. The information content of the digitized images is however limited, and various degradations moreover lead to its further reduction. Digital distribution of the content in the highest image resolution might be therefore unnecessary or uneconomical. In other cases, the highest possible resolution is inevitable if we want to preserve fine scene details or film grain structure for archiving purposes. This paper deals with the image detail content analysis of archive film records. The resolution limit in captured scene image and factors which lower the final resolution are discussed. Methods are proposed to determine the spatial details of the film picture based on the analysis of its digitized image data. These procedures allow determining recommendations for optimal distribution of digitized video content intended for various display devices with lower resolutions. Obtained results are illustrated on spatial downsampling use case scenario, and performance evaluation of the proposed techniques is presented.

Holographic line field en-face OCT with digital adaptive optics in the retina in vivo.

PubMed

Ginner, Laurin; Schmoll, Tilman; Kumar, Abhishek; Salas, Matthias; Pricoupenko, Nastassia; Wurster, Lara M; Leitgeb, Rainer A

2018-02-01

We demonstrate a high-resolution line field en-face time domain optical coherence tomography (OCT) system using an off-axis holography configuration. Line field en-face OCT produces high speed en-face images at rates of up to 100 Hz. The high frame rate favors good phase stability across the lateral field-of-view which is indispensable for digital adaptive optics (DAO). Human retinal structures are acquired in-vivo with a broadband light source at 840 nm, and line rates of 10 kHz to 100 kHz. Structures of different retinal layers, such as photoreceptors, capillaries, and nerve fibers are visualized with high resolution of 2.8 µm and 5.5 µm in lateral directions. Subaperture based DAO is successfully applied to increase the visibility of cone-photoreceptors and nerve fibers. Furthermore, en-face Doppler OCT maps are generated based on calculating the differential phase shifts between recorded lines.

System for objective assessment of image differences in digital cinema

NASA Astrophysics Data System (ADS)

Fliegel, Karel; Krasula, Lukáš; Páta, Petr; Myslík, Jiří; Pecák, Josef; Jícha, Marek

2014-09-01

There is high demand for quick digitization and subsequent image restoration of archived film records. Digitization is very urgent in many cases because various invaluable pieces of cultural heritage are stored on aging media. Only selected records can be reconstructed perfectly using painstaking manual or semi-automatic procedures. This paper aims to answer the question what are the quality requirements on the restoration process in order to obtain acceptably close visual perception of the digitally restored film in comparison to the original analog film copy. This knowledge is very important to preserve the original artistic intention of the movie producers. Subjective experiment with artificially distorted images has been conducted in order to answer the question what is the visual impact of common image distortions in digital cinema. Typical color and contrast distortions were introduced and test images were presented to viewers using digital projector. Based on the outcome of this subjective evaluation a system for objective assessment of image distortions has been developed and its performance tested. The system utilizes calibrated digital single-lens reflex camera and subsequent analysis of suitable features of images captured from the projection screen. The evaluation of captured image data has been optimized in order to obtain predicted differences between the reference and distorted images while achieving high correlation with the results of subjective assessment. The system can be used to objectively determine the difference between analog film and digital cinema images on the projection screen.

The NASA ADS Abstract Service and the Distributed Astronomy Digital Library [and] Project Soup: Comparing Evaluations of Digital Collection Efforts [and] Cross-Organizational Access Management: A Digital Library Authentication and Authorization Architecture [and] BibRelEx: Exploring Bibliographic Databases by Visualization of Annotated Content-based Relations [and] Semantics-Sensitive Retrieval for Digital Picture Libraries [and] Encoded Archival Description: An Introduction and Overview.

ERIC Educational Resources Information Center

Kurtz, Michael J.; Eichorn, Guenther; Accomazzi, Alberto; Grant, Carolyn S.; Demleitner, Markus; Murray, Stephen S.; Jones, Michael L. W.; Gay, Geri K.; Rieger, Robert H.; Millman, David; Bruggemann-Klein, Anne; Klein, Rolf; Landgraf, Britta; Wang, James Ze; Li, Jia; Chan, Desmond; Wiederhold, Gio; Pitti, Daniel V.

1999-01-01

Includes six articles that discuss a digital library for astronomy; comparing evaluations of digital collection efforts; cross-organizational access management of Web-based resources; searching scientific bibliographic databases based on content-based relations between documents; semantics-sensitive retrieval for digital picture libraries; and…

Adaptation and Feasibility Study of a Digital Health Program to Prevent Diabetes among Low-Income Patients: Results from a Partnership between a Digital Health Company and an Academic Research Team

PubMed Central

McDermott, Kelly; Tieu, Lina; Rios, Christina; Gibson, Eliza; Sweet, Cynthia Castro; Payne, Mike

2016-01-01

Background. The feasibility of digital health programs to prevent and manage diabetes in low-income patients has not been adequately explored. Methods. Researchers collaborated with a digital health company to adapt a diabetes prevention program for low-income prediabetes patients at a large safety net clinic. We conducted focus groups to assess patient perspectives, revised lessons for improved readability and cultural relevance to low-income and Hispanic patients, conducted a feasibility study of the adapted program in English and Spanish speaking cohorts, and implemented real-time adaptations to the program for commercial use and for a larger trial of in multiple safety net clinics. Results. The majority of focus group participants were receptive to the program. We modified the curriculum to a 5th-grade reading level and adapted content based on patient feedback. In the feasibility study, 54% of eligible contacted patients expressed interest in enrolling (n = 23). Although some participants' computer access and literacy made registration challenging, they were highly satisfied and engaged (80% logged in at least once/week). Conclusions. Underserved prediabetic patients displayed high engagement and satisfaction with a digital diabetes prevention program despite lower digital literacy skills. The collaboration between researchers and a digital health company enabled iterative improvements in technology implementation to address challenges in low-income populations. PMID:27868070

Programmable Pulser

NASA Technical Reports Server (NTRS)

Baumann, Eric; Merolla, Anthony

1988-01-01

User controls number of clock pulses to prevent burnout. New digital programmable pulser circuit in three formats; freely running, counted, and single pulse. Operates at frequencies up to 5 MHz, with no special consideration given to layout of components or to terminations. Pulser based on sequential circuit with four states and binary counter with appropriate decoding logic. Number of programmable pulses increased beyond 127 by addition of another counter and decoding logic. For very large pulse counts and/or very high frequencies, use synchronous counters to avoid errors caused by propagation delays. Invaluable tool for initial verification or diagnosis of digital or digitally controlled circuity.

Real Time Phase Noise Meter Based on a Digital Signal Processor

NASA Technical Reports Server (NTRS)

Angrisani, Leopoldo; D'Arco, Mauro; Greenhall, Charles A.; Schiano Lo Morille, Rosario

2006-01-01

A digital signal-processing meter for phase noise measurement on sinusoidal signals is dealt with. It enlists a special hardware architecture, made up of a core digital signal processor connected to a data acquisition board, and takes advantage of a quadrature demodulation-based measurement scheme, already proposed by the authors. Thanks to an efficient measurement process and an optimized implementation of its fundamental stages, the proposed meter succeeds in exploiting all hardware resources in such an effective way as to gain high performance and real-time operation. For input frequencies up to some hundreds of kilohertz, the meter is capable both of updating phase noise power spectrum while seamlessly capturing the analyzed signal into its memory, and granting as good frequency resolution as few units of hertz.

Advanced digital SAR processing study

NASA Technical Reports Server (NTRS)

Martinson, L. W.; Gaffney, B. P.; Liu, B.; Perry, R. P.; Ruvin, A.

1982-01-01

A highly programmable, land based, real time synthetic aperture radar (SAR) processor requiring a processed pixel rate of 2.75 MHz or more in a four look system was designed. Variations in range and azimuth compression, number of looks, range swath, range migration and SR mode were specified. Alternative range and azimuth processing algorithms were examined in conjunction with projected integrated circuit, digital architecture, and software technologies. The advaced digital SAR processor (ADSP) employs an FFT convolver algorithm for both range and azimuth processing in a parallel architecture configuration. Algorithm performace comparisons, design system design, implementation tradeoffs and the results of a supporting survey of integrated circuit and digital architecture technologies are reported. Cost tradeoffs and projections with alternate implementation plans are presented.

The FBI compression standard for digitized fingerprint images

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brislawn, C.M.; Bradley, J.N.; Onyshczak, R.J.

1996-10-01

The FBI has formulated national standards for digitization and compression of gray-scale fingerprint images. The compression algorithm for the digitized images is based on adaptive uniform scalar quantization of a discrete wavelet transform subband decomposition, a technique referred to as the wavelet/scalar quantization method. The algorithm produces archival-quality images at compression ratios of around 15 to 1 and will allow the current database of paper fingerprint cards to be replaced by digital imagery. A compliance testing program is also being implemented to ensure high standards of image quality and interchangeability of data between different implementations. We will review the currentmore » status of the FBI standard, including the compliance testing process and the details of the first-generation encoder.« less

FBI compression standard for digitized fingerprint images

NASA Astrophysics Data System (ADS)

Brislawn, Christopher M.; Bradley, Jonathan N.; Onyshczak, Remigius J.; Hopper, Thomas

1996-11-01

The FBI has formulated national standards for digitization and compression of gray-scale fingerprint images. The compression algorithm for the digitized images is based on adaptive uniform scalar quantization of a discrete wavelet transform subband decomposition, a technique referred to as the wavelet/scalar quantization method. The algorithm produces archival-quality images at compression ratios of around 15 to 1 and will allow the current database of paper fingerprint cards to be replaced by digital imagery. A compliance testing program is also being implemented to ensure high standards of image quality and interchangeability of data between different implementations. We will review the current status of the FBI standard, including the compliance testing process and the details of the first-generation encoder.

An Optimized Three-Level Design of Decoder Based on Nanoscale Quantum-Dot Cellular Automata

NASA Astrophysics Data System (ADS)

Seyedi, Saeid; Navimipour, Nima Jafari

2018-03-01

Quantum-dot Cellular Automata (QCA) has been potentially considered as a supersede to Complementary Metal-Oxide-Semiconductor (CMOS) because of its inherent advantages. Many QCA-based logic circuits with smaller feature size, improved operating frequency, and lower power consumption than CMOS have been offered. This technology works based on electron relations inside quantum-dots. Due to the importance of designing an optimized decoder in any digital circuit, in this paper, we design, implement and simulate a new 2-to-4 decoder based on QCA with low delay, area, and complexity. The logic functionality of the 2-to-4 decoder is verified using the QCADesigner tool. The results have shown that the proposed QCA-based decoder has high performance in terms of a number of cells, covered area, and time delay. Due to the lower clock pulse frequency, the proposed 2-to-4 decoder is helpful for building QCA-based sequential digital circuits with high performance.

High content screening of ToxCast compounds using Vala Sciences’ complex cell culturing systems (SOT)

EPA Science Inventory

US EPA’s ToxCast research program evaluates bioactivity for thousands of chemicals utilizing high-throughput screening assays to inform chemical testing decisions. Vala Sciences provides high content, multiplexed assays that utilize quantitative cell-based digital image analysis....

Design of an FPGA-based electronic flow regulator (EFR) for spacecraft propulsion system

NASA Astrophysics Data System (ADS)

Manikandan, J.; Jayaraman, M.; Jayachandran, M.

2011-02-01

This paper describes a scheme for electronically regulating the flow of propellant to the thruster from a high-pressure storage tank used in spacecraft application. Precise flow delivery of propellant to thrusters ensures propulsion system operation at best efficiency by maximizing the propellant and power utilization for the mission. The proposed field programmable gate array (FPGA) based electronic flow regulator (EFR) is used to ensure precise flow of propellant to the thrusters from a high-pressure storage tank used in spacecraft application. This paper presents hardware and software design of electronic flow regulator and implementation of the regulation logic onto an FPGA.Motivation for proposed FPGA-based electronic flow regulation is on the disadvantages of conventional approach of using analog circuits. Digital flow regulation overcomes the analog equivalent as digital circuits are highly flexible, are not much affected due to noise, accurate performance is repeatable, interface is easier to computers, storing facilities are possible and finally failure rate of digital circuits is less. FPGA has certain advantages over ASIC and microprocessor/micro-controller that motivated us to opt for FPGA-based electronic flow regulator. Also the control algorithm being software, it is well modifiable without changing the hardware. This scheme is simple enough to adopt for a wide range of applications, where the flow is to be regulated for efficient operation.The proposed scheme is based on a space-qualified re-configurable field programmable gate arrays (FPGA) and hybrid micro circuit (HMC). A graphical user interface (GUI) based application software is also developed for debugging, monitoring and controlling the electronic flow regulator from PC COM port.

Optimizing digital elevation models (DEMs) accuracy for planning and design of mobile communication networks

NASA Astrophysics Data System (ADS)

Hassan, Mahmoud A.

2004-02-01

Digital elevation models (DEMs) are important tools in the planning, design and maintenance of mobile communication networks. This research paper proposes a method for generating high accuracy DEMs based on SPOT satellite 1A stereo pair images, ground control points (GCP) and Erdas OrthoBASE Pro image processing software. DEMs with 0.2911 m mean error were achieved for the hilly and heavily populated city of Amman. The generated DEM was used to design a mobile communication network resulted in a minimum number of radio base transceiver stations, maximum number of covered regions and less than 2% of dead zones.

On roots and squares - estimation, intuition and creativity

NASA Astrophysics Data System (ADS)

Patkin, Dorit; Gazit, Avikam

2013-12-01

The paper presents findings of a small scale study of a few items related to problem solving with squares and roots, for different teacher groups (pre-service and in-service mathematics teachers: elementary and junior high school). The research participants were asked to explain what would be the units digit of a natural number to be squared in order to obtain a certain units digit as a result. They were also asked to formulate a rule - an algorithm for calculating the square of a 2-digit number which is a multiple of 5. Based on this knowledge and estimation capability, they were required to find, without using calculators, the square roots of given natural numbers. The findings show that most of the participants had only partial intuition regarding the units' digit of a number which is squared when the units' digit of the square is known. At the same time, the participants manifested some evidence of creativity and flow of ideas in identifying the rule for calculating the square of a natural number whose units digit is 5. However, when asked to identify, by means of estimation and based on knowledge from previous items, the square roots of three natural numbers, only few of them managed to find the three roots by estimation.

An exposure indicator for digital radiography: AAPM Task Group 116 (executive summary).

PubMed

Shepard, S Jeff; Wang, Jihong; Flynn, Michael; Gingold, Eric; Goldman, Lee; Krugh, Kerry; Leong, David L; Mah, Eugene; Ogden, Kent; Peck, Donald; Samei, Ehsan; Wang, Jihong; Willis, Charles E

2009-07-01

Digital radiographic imaging systems, such as those using photostimulable storage phosphor, amorphous selenium, amorphous silicon, CCD, and MOSFET technology, can produce adequate image quality over a much broader range of exposure levels than that of screen/film imaging systems. In screen/film imaging, the final image brightness and contrast are indicative of over- and underexposure. In digital imaging, brightness and contrast are often determined entirely by digital postprocessing of the acquired image data. Overexposure and underexposures are not readily recognizable. As a result, patient dose has a tendency to gradually increase over time after a department converts from screen/film-based imaging to digital radiographic imaging. The purpose of this report is to recommend a standard indicator which reflects the radiation exposure that is incident on a detector after every exposure event and that reflects the noise levels present in the image data. The intent is to facilitate the production of consistent, high quality digital radiographic images at acceptable patient doses. This should be based not on image optical density or brightness but on feedback regarding the detector exposure provided and actively monitored by the imaging system. A standard beam calibration condition is recommended that is based on RQA5 but uses filtration materials that are commonly available and simple to use. Recommendations on clinical implementation of the indices to control image quality and patient dose are derived from historical tolerance limits and presented as guidelines.

An exposure indicator for digital radiography: AAPM Task Group 116 (Executive Summary)

PubMed Central

Shepard, S. Jeff; Wang, Jihong; Flynn, Michael; Gingold, Eric; Goldman, Lee; Krugh, Kerry; Leong, David L.; Mah, Eugene; Ogden, Kent; Peck, Donald; Samei, Ehsan; Wang, Jihong; Willis, Charles E.

2009-01-01

Digital radiographic imaging systems, such as those using photostimulable storage phosphor, amorphous selenium, amorphous silicon, CCD, and MOSFET technology, can produce adequate image quality over a much broader range of exposure levels than that of screen/film imaging systems. In screen/film imaging, the final image brightness and contrast are indicative of over- and underexposure. In digital imaging, brightness and contrast are often determined entirely by digital postprocessing of the acquired image data. Overexposure and underexposures are not readily recognizable. As a result, patient dose has a tendency to gradually increase over time after a department converts from screen/film-based imaging to digital radiographic imaging. The purpose of this report is to recommend a standard indicator which reflects the radiation exposure that is incident on a detector after every exposure event and that reflects the noise levels present in the image data. The intent is to facilitate the production of consistent, high quality digital radiographic images at acceptable patient doses. This should be based not on image optical density or brightness but on feedback regarding the detector exposure provided and actively monitored by the imaging system. A standard beam calibration condition is recommended that is based on RQA5 but uses filtration materials that are commonly available and simple to use. Recommendations on clinical implementation of the indices to control image quality and patient dose are derived from historical tolerance limits and presented as guidelines. PMID:19673189

High-Throughput Method for Automated Colony and Cell Counting by Digital Image Analysis Based on Edge Detection

PubMed Central

Choudhry, Priya

2016-01-01

Counting cells and colonies is an integral part of high-throughput screens and quantitative cellular assays. Due to its subjective and time-intensive nature, manual counting has hindered the adoption of cellular assays such as tumor spheroid formation in high-throughput screens. The objective of this study was to develop an automated method for quick and reliable counting of cells and colonies from digital images. For this purpose, I developed an ImageJ macro Cell Colony Edge and a CellProfiler Pipeline Cell Colony Counting, and compared them to other open-source digital methods and manual counts. The ImageJ macro Cell Colony Edge is valuable in counting cells and colonies, and measuring their area, volume, morphology, and intensity. In this study, I demonstrate that Cell Colony Edge is superior to other open-source methods, in speed, accuracy and applicability to diverse cellular assays. It can fulfill the need to automate colony/cell counting in high-throughput screens, colony forming assays, and cellular assays. PMID:26848849

Precise Quantitation of MicroRNA in a Single Cell with Droplet Digital PCR Based on Ligation Reaction.

PubMed

Tian, Hui; Sun, Yuanyuan; Liu, Chenghui; Duan, Xinrui; Tang, Wei; Li, Zhengping

2016-12-06

MicroRNA (miRNA) analysis in a single cell is extremely important because it allows deep understanding of the exact correlation between the miRNAs and cell functions. Herein, we wish to report a highly sensitive and precisely quantitative assay for miRNA detection based on ligation-based droplet digital polymerase chain reaction (ddPCR), which permits the quantitation of miRNA in a single cell. In this ligation-based ddPCR assay, two target-specific oligonucleotide probes can be simply designed to be complementary to the half-sequence of the target miRNA, respectively, which avoids the sophisticated design of reverse transcription and provides high specificity to discriminate a single-base difference among miRNAs with simple operations. After the miRNA-templated ligation, the ddPCR partitions individual ligated products into a water-in-oil droplet and digitally counts the fluorescence-positive and negative droplets after PCR amplification for quantification of the target molecules, which possesses the power of precise quantitation and robustness to variation in PCR efficiency. By integrating the advantages of the precise quantification of ddPCR and the simplicity of the ligation-based PCR, the proposed method can sensitively measure let-7a miRNA with a detection limit of 20 aM (12 copies per microliter), and even a single-base difference can be discriminated in let-7 family members. More importantly, due to its high selectivity and sensitivity, the proposed method can achieve precise quantitation of miRNAs in single-cell lysate. Therefore, the ligation-based ddPCR assay may serve as a useful tool to exactly reveal the miRNAs' actions in a single cell, which is of great importance for the study of miRNAs' biofunction as well as for the related biomedical studies.

Digital Detection and Processing of Multiple Quadrature Harmonics for EPR Spectroscopy

PubMed Central

Ahmad, R.; Som, S.; Kesselring, E.; Kuppusamy, P.; Zweier, J.L.; Potter, L.C.

2010-01-01

A quadrature digital receiver and associated signal estimation procedure are reported for L-band electron paramagnetic resonance (EPR) spectroscopy. The approach provides simultaneous acquisition and joint processing of multiple harmonics in both in-phase and out-of-phase channels. The digital receiver, based on a high-speed dual-channel analog-to-digital converter, allows direct digital down-conversion with heterodyne processing using digital capture of the microwave reference signal. Thus, the receiver avoids noise and nonlinearity associated with analog mixers. Also, the architecture allows for low-Q anti-alias filtering and does not require the sampling frequency to be time-locked to the microwave reference. A noise model applicable for arbitrary contributions of oscillator phase noise is presented, and a corresponding maximum-likelihood estimator of unknown parameters is also reported. The signal processing is applicable for Lorentzian lineshape under nonsaturating conditions. The estimation is carried out using a convergent iterative algorithm capable of jointly processing the in-phase and out-of-phase data in the presence of phase noise and unknown microwave phase. Cramér-Rao bound analysis and simulation results demonstrate a significant reduction in linewidth estimation error using quadrature detection, for both low and high values of phase noise. EPR spectroscopic data are also reported for illustration. PMID:20971667

Digital detection and processing of multiple quadrature harmonics for EPR spectroscopy.

PubMed

Ahmad, R; Som, S; Kesselring, E; Kuppusamy, P; Zweier, J L; Potter, L C

2010-12-01

A quadrature digital receiver and associated signal estimation procedure are reported for L-band electron paramagnetic resonance (EPR) spectroscopy. The approach provides simultaneous acquisition and joint processing of multiple harmonics in both in-phase and out-of-phase channels. The digital receiver, based on a high-speed dual-channel analog-to-digital converter, allows direct digital down-conversion with heterodyne processing using digital capture of the microwave reference signal. Thus, the receiver avoids noise and nonlinearity associated with analog mixers. Also, the architecture allows for low-Q anti-alias filtering and does not require the sampling frequency to be time-locked to the microwave reference. A noise model applicable for arbitrary contributions of oscillator phase noise is presented, and a corresponding maximum-likelihood estimator of unknown parameters is also reported. The signal processing is applicable for Lorentzian lineshape under nonsaturating conditions. The estimation is carried out using a convergent iterative algorithm capable of jointly processing the in-phase and out-of-phase data in the presence of phase noise and unknown microwave phase. Cramér-Rao bound analysis and simulation results demonstrate a significant reduction in linewidth estimation error using quadrature detection, for both low and high values of phase noise. EPR spectroscopic data are also reported for illustration. Copyright © 2010 Elsevier Inc. All rights reserved.

Passive ultrasonics using sub-Nyquist sampling of high-frequency thermal-mechanical noise.

PubMed

Sabra, Karim G; Romberg, Justin; Lani, Shane; Degertekin, F Levent

2014-06-01

Monolithic integration of capacitive micromachined ultrasonic transducer arrays with low noise complementary metal oxide semiconductor electronics minimizes interconnect parasitics thus allowing the measurement of thermal-mechanical (TM) noise. This enables passive ultrasonics based on cross-correlations of diffuse TM noise to extract coherent ultrasonic waves propagating between receivers. However, synchronous recording of high-frequency TM noise puts stringent requirements on the analog to digital converter's sampling rate. To alleviate this restriction, high-frequency TM noise cross-correlations (12-25 MHz) were estimated instead using compressed measurements of TM noise which could be digitized at a sampling frequency lower than the Nyquist frequency.

Web-Based Virtual Microscopy of Digitized Blood Slides for Malaria Diagnosis: An Effective Tool for Skills Assessment in Different Countries and Environments.

PubMed

Ahmed, Laura; Seal, Leonard H; Ainley, Carol; De la Salle, Barbara; Brereton, Michelle; Hyde, Keith; Burthem, John; Gilmore, William Samuel

2016-08-11

Morphological examination of blood films remains the reference standard for malaria diagnosis. Supporting the skills required to make an accurate morphological diagnosis is therefore essential. However, providing support across different countries and environments is a substantial challenge. This paper reports a scheme supplying digital slides of malaria-infected blood within an Internet-based virtual microscope environment to users with different access to training and computing facilities. The feasibility of the approach was established, allowing users to test, record, and compare their own performance with that of other users. From Giemsa stained thick and thin blood films, 56 large high-resolution digital slides were prepared, using high-quality image capture and 63x oil-immersion objective lens. The individual images were combined using the photomerge function of Adobe Photoshop and then adjusted to ensure resolution and reproduction of essential diagnostic features. Web delivery employed the Digital Slidebox platform allowing digital microscope viewing facilities and image annotation with data gathering from participants. Engagement was high with images viewed by 38 participants in five countries in a range of environments and a mean completion rate of 42/56 cases. The rate of parasite detection was 78% and accuracy of species identification was 53%, which was comparable with results of similar studies using glass slides. Data collection allowed users to compare performance with other users over time or for each individual case. Overall, these results demonstrate that users worldwide can effectively engage with the system in a range of environments, with the potential to enhance personal performance through education, external quality assessment, and personal professional development, especially in regions where educational resources are difficult to access.

Compromised encoding of proprioceptively determined joint angles in older adults: the role of working memory and attentional load.

PubMed

Goble, Daniel J; Mousigian, Marianne A; Brown, Susan H

2012-01-01

Perceiving the positions and movements of one's body segments (i.e., proprioception) is critical for movement control. However, this ability declines with older age as has been demonstrated by joint angle matching paradigms in the absence of vision. The aim of the present study was to explore the extent to which reduced working memory and attentional load influence older adult proprioceptive matching performance. Older adults with relatively HIGH versus LOW working memory ability as determined by backward digit span and healthy younger adults, performed memory-based elbow position matching with and without attentional load (i.e., counting by 3 s) during target position encoding. Even without attentional load, older adults with LOW digit spans (i.e., 4 digits or less) had larger matching errors than younger adults. Further, LOW older adults made significantly greater errors when attentional loads were present during proprioceptive target encoding as compared to both younger and older adults with HIGH digit span scores (i.e., 5 digits or greater). These results extend previous position matching results that suggested greater errors in older adults were due to degraded input signals from peripheral mechanoreceptors. Specifically, the present work highlights the role cognitive factors play in the assessment of older adult proprioceptive acuity using memory-based matching paradigms. Older adults with LOW working memory appear prone to compromised proprioceptive encoding, especially when secondary cognitive tasks must be concurrently executed. This may ultimately result in poorer performance on various activities of daily living.

Satellite teleradiology test bed for digital mammography

NASA Astrophysics Data System (ADS)

Barnett, Bruce G.; Dudding, Kathryn E.; Abdel-Malek, Aiman A.; Mitchell, Robert J.

1996-05-01

Teleradiology offers significant improvement in efficiency and patient compliance over current practices in traditional film/screen-based diagnosis. The increasing number of women who need to be screened for breast cancer, including those in remote rural regions, make the advantages of teleradiology especially attractive for digital mammography. At the same time, the size and resolution of digital mammograms are among the most challenging to support in a cost effective teleradiology system. This paper will describe a teleradiology architecture developed for use with digital mammography by GE Corporate Research and Development in collaboration with Massachusetts General Hospital under National Cancer Institute (NCI/NIH) grant number R01 CA60246-01. The testbed architecture is based on the Digital Imaging and Communications in Medicine (DICOM) standard, created by the American College of Radiology and National Electrical Manufacturers Association. The testbed uses several Sun workstations running SunOS, which emulate a rural examination facility connected to a central diagnostic facility, and uses a TCP-based DICOM application to transfer images over a satellite link. Network performance depends on the product of the bandwidth times the round- trip time. A satellite link has a round trip of 513 milliseconds, making the bandwidth-delay a significant problem. This type of high bandwidth, high delay network is called a Long Fat Network, or LFN. The goal of this project was to quantify the performance of the satellite link, and evaluate the effectiveness of TCP over an LFN. Four workstations have Sun's HSI/S (High Speed Interface) option. Two are connected by a cable, and two are connected through a satellite link. Both interfaces have the same T1 bandwidth (1.544 Megabits per second). The only difference was the round trip time. Even with large window buffers, the time to transfer a file over the satellite link was significantly longer, due to the bandwidth-delay. To compensate for this, TCP extensions for LFNs such as the Window Scaling Option (described in RFC1323) were necessary to optimize the use of the link. A high level analysis of throughput, with and without these TCP extensions, will be discussed. Recommendations will be made as to the critical areas for future work.

Compact wavelength-selective optical switch based on digital optical phase conjugation.

PubMed

Li, Zhiyang; Claver, Havyarimana

2013-11-15

In this Letter, we show that digital optical phase conjugation might be utilized to construct a new kind of wavelength-selective switches. When incorporated with a multimode interferometer, these switches have wide bandwidth, high tolerance for fabrication error, and low polarization dependency. They might help to build large-scale multiwavelength nonblocking switching systems, or even to fabricate an optical cross-connecting or routing system on a chip.

Development of Protection and Control Unit for Distribution Substation

NASA Astrophysics Data System (ADS)

Iguchi, Fumiaki; Hayashi, Hideyuki; Takeuchi, Motohiro; Kido, Mitsuyasu; Kobayashi, Takashi; Yanaoka, Atsushi

The Recently, electronics and IT technologies have been rapidly innovated and have been introduced to power system protection & control system to achieve high reliability, maintainability and more functionality. Concerning the distribution substation application, digital relays have been applied for more than 10 years. Because of a number of electronic devices used for it, product cost becomes higher. Also, products installed during the past high-growth period will be at the end of lifetime and will be replaced. Therefore, replacing market is expected to grow and the reduction of cost is demanded. Considering above mentioned background, second generation digital protection and control unit as a successor is designed to have following concepts. Functional integration based on advanced digital technologies, Ethernet LAN based indoor communication network, cost reduction and downsizing. Pondering above concepts, integration of protection and control function is adopted in contrary to the functional segregation applied to the previous system in order to achieve one-unit concept. Also the adoption of Ethernet LAN for inter-unit communication is objective. This report shows the development of second-generation digital relay for distribution substation, which is equipped with control function and Ethernet LAN by reducing the size of auxiliary transformer unit and the same size as previous product is realized.

Adjusting lidar-derived digital terrain models in coastal marshes based on estimated aboveground biomass density

DOE PAGES

Medeiros, Stephen; Hagen, Scott; Weishampel, John; ...

2015-03-25

Digital elevation models (DEMs) derived from airborne lidar are traditionally unreliable in coastal salt marshes due to the inability of the laser to penetrate the dense grasses and reach the underlying soil. To that end, we present a novel processing methodology that uses ASTER Band 2 (visible red), an interferometric SAR (IfSAR) digital surface model, and lidar-derived canopy height to classify biomass density using both a three-class scheme (high, medium and low) and a two-class scheme (high and low). Elevation adjustments associated with these classes using both median and quartile approaches were applied to adjust lidar-derived elevation values closer tomore » true bare earth elevation. The performance of the method was tested on 229 elevation points in the lower Apalachicola River Marsh. The two-class quartile-based adjusted DEM produced the best results, reducing the RMS error in elevation from 0.65 m to 0.40 m, a 38% improvement. The raw mean errors for the lidar DEM and the adjusted DEM were 0.61 ± 0.24 m and 0.32 ± 0.24 m, respectively, thereby reducing the high bias by approximately 49%.« less

High-speed digital phonoscopy images analyzed by Nyquist plots

NASA Astrophysics Data System (ADS)

Yan, Yuling

2012-02-01

Vocal-fold vibration is a key dynamic event in voice production, and the vibratory characteristics of the vocal fold correlate closely with voice quality and health condition. Laryngeal imaging provides direct means to observe the vocal fold vibration; in the past, however, available modalities were either too slow or impractical to resolve the actual vocal fold vibrations. This limitation has now been overcome by high-speed digital imaging (HSDI) (or high-speed digital phonoscopy), which records images of the vibrating vocal folds at a rate of 2000 frames per second or higher- fast enough to resolve a specific, sustained phonatory vocal fold vibration. The subsequent image-based functional analysis of voice is essential to better understanding the mechanism underlying voice production, as well as assisting the clinical diagnosis of voice disorders. Our primary objective is to develop a comprehensive analytical platform for voice analysis using the HSDI recordings. So far, we have developed various analytical approaches for the HSDI-based voice analyses. These include Nyquist plots and associated analysese that are used along with FFT and Spectrogram in the analysis of the HSDI data representing normal voice and specific voice pathologies.

High prevalence of self-reported symptoms of digital ischemia in elite male volleyball players in the Netherlands: a cross-sectional national survey.

PubMed

van de Pol, Daan; Kuijer, P Paul F M; Langenhorst, Ton; Maas, Mario

2012-10-01

In the past 3 years, 6 volleyball players with ischemic digits and small microemboli in the digital arteries of the dominant hand presented themselves in our hospital. These complaints were caused by an aneurysmatic dilation of the posterior circumflex humeral artery (PCHA) with distal occlusion and digital emboli in the isolateral limb. All were elite male volleyball players active in the national top league. Little is known about the exact symptoms associated with PCHA pathological lesions with digital emboli (PCHAP with DE) and its prevalence in elite volleyball players. If vascular injury can be identified at an early stage, thromboembolic complications and irreversible damage to the digits might be prevented. To assess the prevalence of symptoms that are consistent with digital ischemia and may be caused by PCHAP with DE in elite male volleyball players in the Netherlands. Cross-sectional study; Level of evidence, 3. A questionnaire survey was performed among elite volleyball players in the Dutch national top league and the Dutch beach volleyball team. The questionnaire was constructed using literature-based data on symptoms associated with PCHAP with DE, together with data retrieved from medical files. A total of 99 of the 107 athletes participated, with a response rate of 93%. The most frequently reported symptoms associated with PCHAP with DE were cold, blue, or pale digits in the dominant hand during or immediately after practice or competition. The prevalence of these symptoms ranged from 11% to 27%. The prevalence of cold digits during practice and competition was 27%. The prevalence of cold, blue, and pale digits during or immediately after practice and competition was 12%. An unexpectedly high percentage of elite volleyball players reported symptoms that are associated with PCHAP with DE in the dominant hand. Because these athletes are considered potentially at risk for developing critical digital ischemia, further analysis of the presence of digital ischemia and PCHA injury is warranted.

Alpha Control - A new Concept in SPM Control

NASA Astrophysics Data System (ADS)

Spizig, P.; Sanchen, D.; Volswinkler, G.; Ibach, W.; Koenen, J.

2006-03-01

Controlling modern Scanning Probe Microscopes demands highly sophisticated electronics. While flexibility and powerful computing power is of great importance in facilitating the variety of measurement modes, extremely low noise is also a necessity. Accordingly, modern SPM Controller designs are based on digital electronics to overcome the drawbacks of analog designs. While todays SPM controllers are based on DSPs or Microprocessors and often still incorporate analog parts, we are now introducing a completely new approach: Using a Field Programmable Gate Array (FPGA) to implement the digital control tasks allows unrivalled data processing speed by computing all tasks in parallel within a single chip. Time consuming task switching between data acquisition, digital filtering, scanning and the computing of feedback signals can be completely avoided. Together with a star topology to avoid any bus limitations in accessing the variety of ADCs and DACs, this design guarantees for the first time an entirely deterministic timing capability in the nanosecond regime for all tasks. This becomes especially useful for any external experiments which must be synchronized with the scan or for high speed scans that require not only closed loop control of the scanner, but also dynamic correction of the scan movement. Delicate samples additionally benefit from extremely high sample rates, allowing highly resolved signals and low noise levels.

Wideband Spectroscopy: The Design and Implementation of a 3 GHz Bandwidth, 8192 Channel, Polyphase Digital Spectrometer

NASA Technical Reports Server (NTRS)

Monroe, Ryan M.

2011-01-01

A family of state-of-the-art digital Fourier transform spectrometers has been developed, with a combination of high bandwidth and fine resolution unavailable elsewhere. Analog signals consisting of radiation emitted by constituents in planetary atmospheres or galactic sources are downconverted and subsequently digitized by a pair of interleaved Analog-to-Digital Converters, (ADC). This 6 Gsps (giga-sample per second) digital representation of the analog signal is then processed through an FPGA-based streaming Fast Fourier Transform (FFT), the key development described below. Digital spectrometers have many advantages over previously used analog spectrometers, especially in terms of accuracy and resolution, both of which are particularly important for the type of scientific questions to be addressed with next-generation radiometers. the implementation, results and underlying math for this spectrometer, as well as, potential for future extension to even higher bandwidth, resolution and channel orthogonality, needed to support proposed future advanced atmospheric science and radioastronomy, are discussed.

Wideband Spectroscopy: The Design and Implementation of a 3 GHz, 2048 Channel Digital Spectrometer

NASA Technical Reports Server (NTRS)

Monroe, Ryan M.

2011-01-01

A state-of-the-art digital Fourier Transform spectrometer has been developed, with a combination of high bandwidth and fine resolution unavailable elsewhere. Analog signals consisting of radiation emitted by constituents in planetary atmospheres or galactic sources are downconverted and subsequently digitized by a pair of interleaved Analog-to-Digital Converters (ADC). This 6 Gsps (giga sample per second) digital representation of the analog signal is then processed through an FPGA-based streaming Fast Fourier Transform (FFT), the key development described below. Digital spectrometers have many advantages over previously used analog spectrometers, especially in terms of accuracy and resolution, both of which are particularly important for the type of scientific questions to be addressed with next-generation radiometers. The implementation, results and underlying math for this spectrometer, as well as potential for future extension to even higher bandwidth, resolution and channel orthogonality, needed to support proposed future advanced atmospheric science and radioastronomy, are discussed.

The digital eczema centre utrecht.

PubMed

van Os-Medendorp, Harmieke; van Veelen, Carien; Hover, Maaike; Eland-de Kok, Petra; Bruijnzeel-Koomen, Carla; Sonnevelt, Gert-Jan; Mensing, Geert; Pasmans, Suzanne

2010-01-01

The University Medical Centre Utrecht (UMC Utrecht) has developed an eczema portal that combines e-consulting, monitoring and self-management training by a dermatology nurse online for patients and parents of young children with atopic dermatitis (AD). Patient satisfaction with the portal was high. It could be extended to become a Digital Eczema Centre for multidisciplinary collaboration between health-care providers from different locations and the patient. Before starting the construction of the Digital Eczema Centre, the feasibility was examined by carrying out a business case analysis. The purposes, strength and weaknesses showed that the Digital Eczema Centre offered opportunities to improve care for patients with AD. The financial analysis resulted in a medium/best case scenario with a positive result of euro50-240,000 over a period of five years. We expect that the Digital Eczema Centre will increase the accessibility and quality of care. The web-based patient record and the digital chain-of-care promote the involvement of patients, parents and multidisciplinary teams as well as the continuity and coordination of care.

Droplet Digital Enzyme-Linked Oligonucleotide Hybridization Assay for Absolute RNA Quantification.

PubMed

Guan, Weihua; Chen, Liben; Rane, Tushar D; Wang, Tza-Huei

2015-09-03

We present a continuous-flow droplet-based digital Enzyme-Linked Oligonucleotide Hybridization Assay (droplet digital ELOHA) for sensitive detection and absolute quantification of RNA molecules. Droplet digital ELOHA incorporates direct hybridization and single enzyme reaction via the formation of single probe-RNA-probe (enzyme) complex on magnetic beads. It enables RNA detection without reverse transcription and PCR amplification processes. The magnetic beads are subsequently encapsulated into a large number of picoliter-sized droplets with enzyme substrates in a continuous-flow device. This device is capable of generating droplets at high-throughput. It also integrates in-line enzymatic incubation and detection of fluorescent products. Our droplet digital ELOHA is able to accurately quantify (differentiate 40% difference) as few as ~600 RNA molecules in a 1 mL sample (equivalent to 1 aM or lower) without molecular replication. The absolute quantification ability of droplet digital ELOHA is demonstrated with the analysis of clinical Neisseria gonorrhoeae 16S rRNA to show its potential value in real complex samples.

Droplet Digital Enzyme-Linked Oligonucleotide Hybridization Assay for Absolute RNA Quantification

PubMed Central

Guan, Weihua; Chen, Liben; Rane, Tushar D.; Wang, Tza-Huei

2015-01-01

We present a continuous-flow droplet-based digital Enzyme-Linked Oligonucleotide Hybridization Assay (droplet digital ELOHA) for sensitive detection and absolute quantification of RNA molecules. Droplet digital ELOHA incorporates direct hybridization and single enzyme reaction via the formation of single probe-RNA-probe (enzyme) complex on magnetic beads. It enables RNA detection without reverse transcription and PCR amplification processes. The magnetic beads are subsequently encapsulated into a large number of picoliter-sized droplets with enzyme substrates in a continuous-flow device. This device is capable of generating droplets at high-throughput. It also integrates in-line enzymatic incubation and detection of fluorescent products. Our droplet digital ELOHA is able to accurately quantify (differentiate 40% difference) as few as ~600 RNA molecules in a 1 mL sample (equivalent to 1 aM or lower) without molecular replication. The absolute quantification ability of droplet digital ELOHA is demonstrated with the analysis of clinical Neisseria gonorrhoeae 16S rRNA to show its potential value in real complex samples. PMID:26333806

[Interface interconnection and data integration in implementing of digital operating room].

PubMed

Feng, Jingyi; Chen, Hua; Liu, Jiquan

2011-10-01

The digital operating-room, with highly integrated clinical information, is very important for rescuing lives of patients and improving quality of operations. Since equipments in domestic operating-rooms have diversified interface and nonstandard communication protocols, designing and implementing an integrated data sharing program for different kinds of diagnosing, monitoring, and treatment equipments become a key point in construction of digital operating room. This paper addresses interface interconnection and data integration for commonly used clinical equipments from aspects of hardware interface, interface connection and communication protocol, and offers a solution for interconnection and integration of clinical equipments in heterogeneous environment. Based on the solution, a case of an optimal digital operating-room is presented in this paper. Comparing with the international solution for digital operating-room, the solution proposed in this paper is more economical and effective. And finally, this paper provides a proposal for the platform construction of digital perating-room as well as a viewpoint for standardization of domestic clinical equipments.

The role of data fusion in predictive maintenance using digital twin

NASA Astrophysics Data System (ADS)

Liu, Zheng; Meyendorf, Norbert; Mrad, Nezih

2018-04-01

Modern aerospace industry is migrating from reactive to proactive and predictive maintenance to increase platform operational availability and efficiency, extend its useful life cycle and reduce its life cycle cost. Multiphysics modeling together with data-driven analytics generate a new paradigm called "Digital Twin." The digital twin is actually a living model of the physical asset or system, which continually adapts to operational changes based on the collected online data and information, and can forecast the future of the corresponding physical counterpart. This paper reviews the overall framework to develop a digital twin coupled with the industrial Internet of Things technology to advance aerospace platforms autonomy. Data fusion techniques particularly play a significant role in the digital twin framework. The flow of information from raw data to high-level decision making is propelled by sensor-to-sensor, sensor-to-model, and model-to-model fusion. This paper further discusses and identifies the role of data fusion in the digital twin framework for aircraft predictive maintenance.

Droplet Digital Enzyme-Linked Oligonucleotide Hybridization Assay for Absolute RNA Quantification

NASA Astrophysics Data System (ADS)

Guan, Weihua; Chen, Liben; Rane, Tushar D.; Wang, Tza-Huei

2015-09-01

We present a continuous-flow droplet-based digital Enzyme-Linked Oligonucleotide Hybridization Assay (droplet digital ELOHA) for sensitive detection and absolute quantification of RNA molecules. Droplet digital ELOHA incorporates direct hybridization and single enzyme reaction via the formation of single probe-RNA-probe (enzyme) complex on magnetic beads. It enables RNA detection without reverse transcription and PCR amplification processes. The magnetic beads are subsequently encapsulated into a large number of picoliter-sized droplets with enzyme substrates in a continuous-flow device. This device is capable of generating droplets at high-throughput. It also integrates in-line enzymatic incubation and detection of fluorescent products. Our droplet digital ELOHA is able to accurately quantify (differentiate 40% difference) as few as ~600 RNA molecules in a 1 mL sample (equivalent to 1 aM or lower) without molecular replication. The absolute quantification ability of droplet digital ELOHA is demonstrated with the analysis of clinical Neisseria gonorrhoeae 16S rRNA to show its potential value in real complex samples.

Performance of the Fully Digital FPGA-Based Front-End Electronics for the GALILEO Array

NASA Astrophysics Data System (ADS)

Barrientos, D.; Bellato, M.; Bazzacco, D.; Bortolato, D.; Cocconi, P.; Gadea, A.; González, V.; Gulmini, M.; Isocrate, R.; Mengoni, D.; Pullia, A.; Recchia, F.; Rosso, D.; Sanchis, E.; Toniolo, N.; Ur, C. A.; Valiente-Dobón, J. J.

2015-12-01

In this work we present the architecture and results of a fully digital Front End Electronics (FEE) read out system developed for the GALILEO array. The FEE system, developed in collaboration with the Advanced Gamma Tracking Array (AGATA) collaboration, is composed of three main blocks: preamplifiers, digitizers and preprocessing electronics. The slow control system contains a custom Linux driver, a dynamic library and a server implementing network services. This work presents the first results of the digital FEE system coupled with a GALILEO germanium detector, which has demonstrated the capability to achieve an energy resolution of 1.530/00 at an energy of 1.33 MeV, similar to the one obtained with a conventional analog system. While keeping a good performance in terms of energy resolution, digital electronics will allow to instrument the full GALILEO array with a versatile system with high integration and low power consumption and costs.

Direct digital conversion detector technology

NASA Astrophysics Data System (ADS)

Mandl, William J.; Fedors, Richard

1995-06-01

Future imaging sensors for the aerospace and commercial video markets will depend on low cost, high speed analog-to-digital (A/D) conversion to efficiently process optical detector signals. Current A/D methods place a heavy burden on system resources, increase noise, and limit the throughput. This paper describes a unique method for incorporating A/D conversion right on the focal plane array. This concept is based on Sigma-Delta sampling, and makes optimum use of the active detector real estate. Combined with modern digital signal processors, such devices will significantly increase data rates off the focal plane. Early conversion to digital format will also decrease the signal susceptibility to noise, lowering the communications bit error rate. Computer modeling of this concept is described, along with results from several simulation runs. A potential application for direct digital conversion is also reviewed. Future uses for this technology could range from scientific instruments to remote sensors, telecommunications gear, medical diagnostic tools, and consumer products.

High-Quality 3d Models and Their Use in a Cultural Heritage Conservation Project

NASA Astrophysics Data System (ADS)

Tucci, G.; Bonora, V.; Conti, A.; Fiorini, L.

2017-08-01

Cultural heritage digitization and 3D modelling processes are mainly based on laser scanning and digital photogrammetry techniques to produce complete, detailed and photorealistic three-dimensional surveys: geometric as well as chromatic aspects, in turn testimony of materials, work techniques, state of preservation, etc., are documented using digitization processes. The paper explores the topic of 3D documentation for conservation purposes; it analyses how geomatics contributes in different steps of a restoration process and it presents an overview of different uses of 3D models for the conservation and enhancement of the cultural heritage. The paper reports on the project to digitize the earthenware frieze of the Ospedale del Ceppo in Pistoia (Italy) for 3D documentation, restoration work support, and digital and physical reconstruction and integration purposes. The intent to design an exhibition area suggests new ways to take advantage of 3D data originally acquired for documentation and scientific purposes.

Virology: The Next Generation from Digital PCR to Single Virion Genomics

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, Richard A.; Brazelton De Cardenas, Jessica N.; Hayden, Randall T.

In the past 25 years, virology has had major technology breakthroughs stemming first from the introduction of nucleic acid amplification testing, but more recently from the use of next-generation sequencing, digital PCR, and the possibility of single virion genomics. These technologies have and will improve diagnosis and disease state monitoring in clinical settings, aid in environmental monitoring, and reveal the vast genetic potential of viruses. Using the principle of limiting dilution, digital PCR amplifies single molecules of DNA in highly partitioned endpoint reactions and reads each of those reactions as either positive or negative based on the presence or absencemore » of target fluorophore. In this review, digital PCR will be highlighted along with current studies, advantages/disadvantages, and future perspectives with regard to digital PCR, viral load testing, and the possibility of single virion genomics.« less

Full-field modal analysis during base motion excitation using high-speed 3D digital image correlation

NASA Astrophysics Data System (ADS)

Molina-Viedma, Ángel J.; López-Alba, Elías; Felipe-Sesé, Luis; Díaz, Francisco A.

2017-10-01

In recent years, many efforts have been made to exploit full-field measurement optical techniques for modal identification. Three-dimensional digital image correlation using high-speed cameras has been extensively employed for this purpose. Modal identification algorithms are applied to process the frequency response functions (FRF), which relate the displacement response of the structure to the excitation force. However, one of the most common tests for modal analysis involves the base motion excitation of a structural element instead of force excitation. In this case, the relationship between response and excitation is typically based on displacements, which are known as transmissibility functions. In this study, a methodology for experimental modal analysis using high-speed 3D digital image correlation and base motion excitation tests is proposed. In particular, a cantilever beam was excited from its base with a random signal, using a clamped edge join. Full-field transmissibility functions were obtained through the beam and converted into FRF for proper identification, considering a single degree-of-freedom theoretical conversion. Subsequently, modal identification was performed using a circle-fit approach. The proposed methodology facilitates the management of the typically large amounts of data points involved in the DIC measurement during modal identification. Moreover, it was possible to determine the natural frequencies, damping ratios and full-field mode shapes without requiring any additional tests. Finally, the results were experimentally validated by comparing them with those obtained by employing traditional accelerometers, analytical models and finite element method analyses. The comparison was performed by using the quantitative indicator modal assurance criterion. The results showed a high level of correspondence, consolidating the proposed experimental methodology.

Quantification of depositional changes and paleo-seismic activities from laminated sediments using outcrop data

NASA Astrophysics Data System (ADS)

Weidlich, O.; Bernecker, M.

2004-04-01

Measurements of laminations from marine and limnic sediments are commonly a time-consuming procedure. However, the resulting quantitative proxies are of importance for the interpretation of both, climate changes and paleo-seismic activities. Digital image analysis accelerates the generation and interpretation of large data sets from laminated sediments based on contrasting grey values of dark and light laminae. Statistical transformation and correlation of the grey value signals reflect high frequency cycles due to changing mean laminae thicknesses, and thus provide data monitoring climate change. Perturbations (e.g., slumping structures, seismites, and tsunamites) of the commonly continuous laminae record seismic activities and obtain proxies for paleo-earthquake frequency. Using outcrop data from (i) the Pleistocene Lisan Formation of Jordan (Dead Sea Basin) and (ii) the Carboniferous-Permian Copacabana Formation of Bolivia (Lake Titicaca), we present a two-step approach to gain high-resolution time series based on field data for both purposes from unconsolidated and lithified outcrops. Step 1 concerns the construction of a continuous digital phototransect and step 2 covers the creation of a grey density curve based on digital photos along a line transect using image analysis. The applied automated image analysis technique provides a continuous digital record of the studied sections and, therefore, serves as useful tool for the evaluation of further proxy data. Analysing the obtained grey signal of the light and dark laminae of varves using phototransects, we discuss the potential and limitations of the proposed technique.

The x-ray light valve: a potentially low-cost, digital radiographic imaging system-concept and implementation considerations.

PubMed

Webster, Christie Ann; Koprinarov, Ivaylo; Germann, Stephen; Rowlands, J A

2008-03-01

New x-ray radiographic systems based on large-area flat-panel technology have revolutionized our capability to produce digital x-ray images. However, these imagers are extraordinarily expensive compared to the systems they are replacing. Hence, there is a need for a low-cost digital imaging system for general applications in radiology. A novel potentially low-cost radiographic imaging system based on established technologies is proposed-the X-Ray Light Valve (XLV). This is a potentially high-quality digital x-ray detector made of a photoconducting layer and a liquid-crystal cell, physically coupled in a sandwich structure. Upon exposure to x rays, charge is collected on the surface of the photoconductor. This causes a change in the optical properties of the liquid-crystal cell and a visible image is generated. Subsequently, it is digitized by a scanned optical imager. The image formation is based on controlled modulation of light from an external source. The operation and practical implementation of the XLV system are described. The potential performance of the complete system and issues related to sensitivity, spatial resolution, noise, and speed are discussed. The feasibility of clinical use of an XLV device based on amorphous selenium (a-Se) as the photoconductor and a reflective electrically controlled birefringence cell is analyzed. The results of our analysis indicate that the XLV can potentially be adapted to a wide variety of radiographic tasks.

Scoping of Flood Hazard Mapping Needs for Coos County, New Hampshire

DTIC Science & Technology

2006-01-01

Technical Partner DEM Digital Elevation Model DFIRM Digital Flood Insurance Rate Map DOQ Digital Orthophoto Quadrangle DOQQ Digital Ortho Quarter Quadrangle...color Digital Orthophoto Quadrangles (DOQs)). Remote sensing, base map information, GIS data (for example, contour data, E911 data, Digital Elevation...the feature types found on USGS topographic maps. More recently developed data were derived from digital orthophotos providing improved base map

Broadband set-top box using MAP-CA processor

NASA Astrophysics Data System (ADS)

Bush, John E.; Lee, Woobin; Basoglu, Chris

2001-12-01

Advances in broadband access are expected to exert a profound impact in our everyday life. It will be the key to the digital convergence of communication, computer and consumer equipment. A common thread that facilitates this convergence comprises digital media and Internet. To address this market, Equator Technologies, Inc., is developing the Dolphin broadband set-top box reference platform using its MAP-CA Broadband Signal ProcessorT chip. The Dolphin reference platform is a universal media platform for display and presentation of digital contents on end-user entertainment systems. The objective of the Dolphin reference platform is to provide a complete set-top box system based on the MAP-CA processor. It includes all the necessary hardware and software components for the emerging broadcast and the broadband digital media market based on IP protocols. Such reference design requires a broadband Internet access and high-performance digital signal processing. By using the MAP-CA processor, the Dolphin reference platform is completely programmable, allowing various codecs to be implemented in software, such as MPEG-2, MPEG-4, H.263 and proprietary codecs. The software implementation also enables field upgrades to keep pace with evolving technology and industry demands.

Simulation of continuously logical base cells (CL BC) with advanced functions for analog-to-digital converters and image processors

NASA Astrophysics Data System (ADS)

Krasilenko, Vladimir G.; Lazarev, Alexander A.; Nikitovich, Diana V.

2017-10-01

The paper considers results of design and modeling of continuously logical base cells (CL BC) based on current mirrors (CM) with functions of preliminary analogue and subsequent analogue-digital processing for creating sensor multichannel analog-to-digital converters (SMC ADCs) and image processors (IP). For such with vector or matrix parallel inputs-outputs IP and SMC ADCs it is needed active basic photosensitive cells with an extended electronic circuit, which are considered in paper. Such basic cells and ADCs based on them have a number of advantages: high speed and reliability, simplicity, small power consumption, high integration level for linear and matrix structures. We show design of the CL BC and ADC of photocurrents and their various possible implementations and its simulations. We consider CL BC for methods of selection and rank preprocessing and linear array of ADCs with conversion to binary codes and Gray codes. In contrast to our previous works here we will dwell more on analogue preprocessing schemes for signals of neighboring cells. Let us show how the introduction of simple nodes based on current mirrors extends the range of functions performed by the image processor. Each channel of the structure consists of several digital-analog cells (DC) on 15-35 CMOS. The amount of DC does not exceed the number of digits of the formed code, and for an iteration type, only one cell of DC, complemented by the device of selection and holding (SHD), is required. One channel of ADC with iteration is based on one DC-(G) and SHD, and it has only 35 CMOS transistors. In such ADCs easily parallel code can be realized and also serial-parallel output code. The circuits and simulation results of their design with OrCAD are shown. The supply voltage of the DC is 1.8÷3.3V, the range of an input photocurrent is 0.1÷24μA, the transformation time is 20÷30nS at 6-8 bit binary or Gray codes. The general power consumption of the ADC with iteration is only 50÷100μW, if the maximum input current is 4μA. Such simple structure of linear array of ADCs with low power consumption and supply voltage 3.3V, and at the same time with good dynamic characteristics (frequency of digitization even for 1.5μm CMOS-technologies is 40÷50 MHz, and can be increased up to 10 times) and accuracy characteristics are show. The SMC ADCs based on CL BC and CM opens new prospects for realization of linear and matrix IP and photo-electronic structures with matrix operands, which are necessary for neural networks, digital optoelectronic processors, neural-fuzzy controllers.

Classification of cloud fields based on textural characteristics

NASA Technical Reports Server (NTRS)

Welch, R. M.; Sengupta, S. K.; Chen, D. W.

1987-01-01

The present study reexamines the applicability of texture-based features for automatic cloud classification using very high spatial resolution (57 m) Landsat multispectral scanner digital data. It is concluded that cloud classification can be accomplished using only a single visible channel.

Universal digital high-resolution melt: a novel approach to broad-based profiling of heterogeneous biological samples.

PubMed

Fraley, Stephanie I; Hardick, Justin; Masek, Billie J; Jo Masek, Billie; Athamanolap, Pornpat; Rothman, Richard E; Gaydos, Charlotte A; Carroll, Karen C; Wakefield, Teresa; Wang, Tza-Huei; Yang, Samuel

2013-10-01

Comprehensive profiling of nucleic acids in genetically heterogeneous samples is important for clinical and basic research applications. Universal digital high-resolution melt (U-dHRM) is a new approach to broad-based PCR diagnostics and profiling technologies that can overcome issues of poor sensitivity due to contaminating nucleic acids and poor specificity due to primer or probe hybridization inaccuracies for single nucleotide variations. The U-dHRM approach uses broad-based primers or ligated adapter sequences to universally amplify all nucleic acid molecules in a heterogeneous sample, which have been partitioned, as in digital PCR. Extensive assay optimization enables direct sequence identification by algorithm-based matching of melt curve shape and Tm to a database of known sequence-specific melt curves. We show that single-molecule detection and single nucleotide sensitivity is possible. The feasibility and utility of U-dHRM is demonstrated through detection of bacteria associated with polymicrobial blood infection and microRNAs (miRNAs) associated with host response to infection. U-dHRM using broad-based 16S rRNA gene primers demonstrates universal single cell detection of bacterial pathogens, even in the presence of larger amounts of contaminating bacteria; U-dHRM using universally adapted Lethal-7 miRNAs in a heterogeneous mixture showcases the single copy sensitivity and single nucleotide specificity of this approach.

Topographic correction realization based on the CBERS-02B image

NASA Astrophysics Data System (ADS)

Qin, Hui-ping; Yi, Wei-ning; Fang, Yong-hua

2011-08-01

The special topography of mountain terrain will induce the retrieval distortion in same species and surface spectral lines. In order to improve the research accuracy of topographic surface characteristic, many researchers have focused on topographic correction. Topographic correction methods can be statistical-empirical model or physical model, in which the methods based on the digital elevation model data are most popular. Restricted by spatial resolution, previous model mostly corrected topographic effect based on Landsat TM image, whose spatial resolution is 30 meter that can be easily achieved from internet or calculated from digital map. Some researchers have also done topographic correction based on high spatial resolution images, such as Quickbird and Ikonos, but there is little correlative research on the topographic correction of CBERS-02B image. In this study, liao-ning mountain terrain was taken as the objective. The digital elevation model data was interpolated to 2.36 meter by 15 meter original digital elevation model one meter by one meter. The C correction, SCS+C correction, Minnaert correction and Ekstrand-r were executed to correct the topographic effect. Then the corrected results were achieved and compared. The images corrected with C correction, SCS+C correction, Minnaert correction and Ekstrand-r were compared, and the scatter diagrams between image digital number and cosine of solar incidence angel with respect to surface normal were shown. The mean value, standard variance, slope of scatter diagram, and separation factor were statistically calculated. The analysed result shows that the shadow is weakened in corrected images than the original images, and the three-dimensional affect is removed. The absolute slope of fitting lines in scatter diagram is minished. Minnaert correction method has the most effective result. These demonstrate that the former correction methods can be successfully adapted to CBERS-02B images. The DEM data can be interpolated step by step to get the corresponding spatial resolution approximately for the condition that high spatial resolution elevation data is hard to get.

Detection of SEA-type α-thalassemia in embryo biopsies by digital PCR.

PubMed

Lee, Ta-Hsien; Hsu, Ya-Chiung; Chang, Chia Lin

2017-08-01

Accurate and efficient pre-implantation genetic diagnosis (PGD) based on the analysis of single or oligo-cells is needed for timely identification of embryos that are affected by deleterious genetic traits in in vitro fertilization (IVF) clinics. Polymerase chain reaction (PCR) is the backbone of modern genetic diagnoses, and a spectrum of PCR-based techniques have been used to detect various thalassemia mutations in prenatal diagnosis (PND) and PGD. Among thalassemias, SEA-type α-thalassemia is the most common variety found in Asia, and can lead to Bart's hydrops fetalis and serious maternal complications. To formulate an efficient digital PCR for clinical diagnosis of SEA-type α-thalassemia in cultured embryos, we conducted a pilot study to detect the α-globin and SEA-type deletion alleles in blastomere biopsies with a highly sensitive microfluidics-based digital PCR method. Genomic DNA from embryo biopsy samples were extracted, and crude DNA extracts were first amplified by a conventional PCR procedure followed by a nested PCR reaction with primers and probes that are designed for digital PCR amplification. Analysis of microfluidics-based PCR reactions showed that robust signals for normal α-globin and SEA-type deletion alleles, together with an internal control gene, can be routinely generated using crude embryo biopsies after a 10 6 -fold dilution of primary PCR products. The SEA-type deletion in cultured embryos can be sensitively diagnosed with the digital PCR procedure in clinics. The adoption of this robust PGD method could prevent the implantation of IVF embryos that are destined to develop Bart's hydrops fetalis in a timely manner. The results also help inform future development of a standard digital PCR procedure for cost-effective PGD of α-thalassemia in a standard IVF clinic. Copyright © 2017. Published by Elsevier B.V.

A high performance DAC /DDS daughter module for the RHIC LLRF platform

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hayes, T.; Harvey, M.; Narayan, G.

The RHIC LLRF upgrade is a flexible, modular system. Output signals are generated by a custom designed XMC card with 4 high speed digital to analog (DAC) converters interfaced to a high performance field programmable gate array (FPGA). This paper discusses the hardware details of the XMC DAC board as well as the implementation of a low noise rf synthesizer with digital IQ modulation. This synthesizer also provides injection phase cogging and frequency hop rebucketing capabilities. A new modular RHIC LLRF system was recently designed and commissioned based on custom designed XMC cards. As part of that effort a highmore » speed, four channel DAC board was designed. The board uses Maxim MAX5891 16 bit DACs with a maximum update rate of 600 Msps. Since this module is intended to be used for many different systems throughout the Collider Accelerator complex, it was designed to be as generic as possible. One major application of this DAC card is to implement digital synthesizers to provide drive signals to the various cavities at RHIC. Since RHIC is a storage ring with stores that typically last many hours, extremely low RF noise is a critical requirement. Synchrotron frequencies at RHIC range from a few hertz to several hundred hertz depending on the species and point in the acceleration cycle so close in phase noise is a major concern. The RHIC LLRF system uses the Update Link, a deterministic, high speed data link that broadcasts the revolution frequency and the synchronous phase angle. The digital synthesizers use this data to generate a properly phased analog drive signal. The synthesizers must also provide smooth phase shifts for cogging and support frequency shift rebucketing. One additional feature implemented in the FPGA is a digital waveform generator (WFG) that generates I and Q data pairs based on a user selected amplitude and phase profile as a function of time.« less

Development of ultra-high temperature material characterization capabilities using digital image correlation analysis

NASA Astrophysics Data System (ADS)

Cline, Julia Elaine

2011-12-01

Ultra-high temperature deformation measurements are required to characterize the thermo-mechanical response of material systems for thermal protection systems for aerospace applications. The use of conventional surface-contacting strain measurement techniques is not practical in elevated temperature conditions. Technological advancements in digital imaging provide impetus to measure full-field displacement and determine strain fields with sub-pixel accuracy by image processing. In this work, an Instron electromechanical axial testing machine with a custom-designed high temperature gripping mechanism is used to apply quasi-static tensile loads to graphite specimens heated to 2000°F (1093°C). Specimen heating via Joule effect is achieved and maintained with a custom-designed temperature control system. Images are captured at monotonically increasing load levels throughout the test duration using an 18 megapixel Canon EOS Rebel T2i digital camera with a modified Schneider Kreutznach telecentric lens and a combination of blue light illumination and narrow band-pass filter system. Images are processed using an open-source Matlab-based digital image correlation (DIC) code. Validation of source code is performed using Mathematica generated images with specified known displacement fields in order to gain confidence in accurate software tracking capabilities. Room temperature results are compared with extensometer readings. Ultra-high temperature strain measurements for graphite are obtained at low load levels, demonstrating the potential for non-contacting digital image correlation techniques to accurately determine full-field strain measurements at ultra-high temperature. Recommendations are given to improve the experimental set-up to achieve displacement field measurements accurate to 1/10 pixel and strain field accuracy of less than 2%.

Broad-Bandwidth FPGA-Based Digital Polyphase Spectrometer

NASA Technical Reports Server (NTRS)

Jamot, Robert F.; Monroe, Ryan M.

2012-01-01

With present concern for ecological sustainability ever increasing, it is desirable to model the composition of Earth s upper atmosphere accurately with regards to certain helpful and harmful chemicals, such as greenhouse gases and ozone. The microwave limb sounder (MLS) is an instrument designed to map the global day-to-day concentrations of key atmospheric constituents continuously. One important component in MLS is the spectrometer, which processes the raw data provided by the receivers into frequency-domain information that cannot only be transmitted more efficiently, but also processed directly once received. The present-generation spectrometer is fully analog. The goal is to include a fully digital spectrometer in the next-generation sensor. In a digital spectrometer, incoming analog data must be converted into a digital format, processed through a Fourier transform, and finally accumulated to reduce the impact of input noise. While the final design will be placed on an application specific integrated circuit (ASIC), the building of these chips is prohibitively expensive. To that end, this design was constructed on a field-programmable gate array (FPGA). A family of state-of-the-art digital Fourier transform spectrometers has been developed, with a combination of high bandwidth and fine resolution. Analog signals consisting of radiation emitted by constituents in planetary atmospheres or galactic sources are downconverted and subsequently digitized by a pair of interleaved analog-to-digital converters (ADCs). This 6-Gsps (gigasample per second) digital representation of the analog signal is then processed through an FPGA-based streaming fast Fourier transform (FFT). Digital spectrometers have many advantages over previously used analog spectrometers, especially in terms of accuracy and resolution, both of which are particularly important for the type of scientific questions to be addressed with next-generation radiometers.

Ultramap v3 - a Revolution in Aerial Photogrammetry

NASA Astrophysics Data System (ADS)

Reitinger, B.; Sormann, M.; Zebedin, L.; Schachinger, B.; Hoefler, M.; Tomasi, R.; Lamperter, M.; Gruber, B.; Schiester, G.; Kobald, M.; Unger, M.; Klaus, A.; Bernoegger, S.; Karner, K.; Wiechert, A.; Ponticelli, M.; Gruber, M.

2012-07-01

In the last years, Microsoft has driven innovation in the aerial photogrammetry community. Besides the market leading camera technology, UltraMap has grown to an outstanding photogrammetric workflow system which enables users to effectively work with large digital aerial image blocks in a highly automated way. Best example is the project-based color balancing approach which automatically balances images to a homogeneous block. UltraMap V3 continues innovation, and offers a revolution in terms of ortho processing. A fully automated dense matching module strives for high precision digital surface models (DSMs) which are calculated either on CPUs or on GPUs using a distributed processing framework. By applying constrained filtering algorithms, a digital terrain model can be derived which in turn can be used for fully automated traditional ortho texturing. By having the knowledge about the underlying geometry, seamlines can be generated automatically by applying cost functions in order to minimize visual disturbing artifacts. By exploiting the generated DSM information, a DSMOrtho is created using the balanced input images. Again, seamlines are detected automatically resulting in an automatically balanced ortho mosaic. Interactive block-based radiometric adjustments lead to a high quality ortho product based on UltraCam imagery. UltraMap v3 is the first fully integrated and interactive solution for supporting UltraCam images at best in order to deliver DSM and ortho imagery.

Reconstruction of measurable three-dimensional point cloud model based on large-scene archaeological excavation sites

NASA Astrophysics Data System (ADS)

Zhang, Chun-Sen; Zhang, Meng-Meng; Zhang, Wei-Xing

2017-01-01

This paper outlines a low-cost, user-friendly photogrammetric technique with nonmetric cameras to obtain excavation site digital sequence images, based on photogrammetry and computer vision. Digital camera calibration, automatic aerial triangulation, image feature extraction, image sequence matching, and dense digital differential rectification are used, combined with a certain number of global control points of the excavation site, to reconstruct the high precision of measured three-dimensional (3-D) models. Using the acrobatic figurines in the Qin Shi Huang mausoleum excavation as an example, our method solves the problems of little base-to-height ratio, high inclination, unstable altitudes, and significant ground elevation changes affecting image matching. Compared to 3-D laser scanning, the 3-D color point cloud obtained by this method can maintain the same visual result and has advantages of low project cost, simple data processing, and high accuracy. Structure-from-motion (SfM) is often used to reconstruct 3-D models of large scenes and has lower accuracy if it is a reconstructed 3-D model of a small scene at close range. Results indicate that this method quickly achieves 3-D reconstruction of large archaeological sites and produces heritage site distribution of orthophotos providing a scientific basis for accurate location of cultural relics, archaeological excavations, investigation, and site protection planning. This proposed method has a comprehensive application value.

Enhanced optical security by using information carrier digital screening

NASA Astrophysics Data System (ADS)

Koltai, Ferenc; Adam, Bence

2004-06-01

Jura has developed different security features based on Information Carrier Digital Screening. Substance of such features is that a non-visible secondary image is encoded in a visible primary image. The encoded image will be visible only by using a decoding device. One of such developments is JURA's Invisible Personal Information (IPI) is widely used in high security documents, where personal data of the document holder are encoded in the screen of the document holder's photography and they can be decoded by using an optical decoding device. In order to make document verification fully automated, enhance security and eliminate human factors, digital version of IPI, the D-IPI was developed. A special 2D-barcode structure was designed, which contains sufficient quantity of encoded digital information and can be embedded into the photo. Other part of Digital-IPI is the reading software, that is able to retrieve the encoded information with high reliability. The reading software developed with a specific 2D structure is providing the possibility of a forensic analysis. Such analysis will discover all kind of manipulations -- globally, if the photography was simply changed and selectively, if only part of the photography was manipulated. Digital IPI is a good example how benefits of digital technology can be exploited by using optical security and how technology for optical security can be converted into digital technology. The D-IPI process is compatible with all current personalization printers and materials (polycarbonate, PVC, security papers, Teslin-foils, etc.) and can provide any document with enhanced security and tamper-resistance.

A smartphone photogrammetry method for digitizing prosthetic socket interiors.

PubMed

Hernandez, Amaia; Lemaire, Edward

2017-04-01

Prosthetic CAD/CAM systems require accurate 3D limb models; however, difficulties arise when working from the person's socket since current 3D scanners have difficulties scanning socket interiors. While dedicated scanners exist, they are expensive and the cost may be prohibitive for a limited number of scans per year. A low-cost and accessible photogrammetry method for socket interior digitization is proposed, using a smartphone camera and cloud-based photogrammetry services. 15 two-dimensional images of the socket's interior are captured using a smartphone camera. A 3D model is generated using cloud-based software. Linear measurements were comparing between sockets and the related 3D models. 3D reconstruction accuracy averaged 2.6 ± 2.0 mm and 0.086 ± 0.078 L, which was less accurate than models obtained by high quality 3D scanners. However, this method would provide a viable 3D digital socket reproduction that is accessible and low-cost, after processing in prosthetic CAD software. Clinical relevance The described method provides a low-cost and accessible means to digitize a socket interior for use in prosthetic CAD/CAM systems, employing a smartphone camera and cloud-based photogrammetry software.

Compact multichannel MEMS based spectrometer for FBG sensing

NASA Astrophysics Data System (ADS)

Ganziy, D.; Rose, B.; Bang, O.

2017-04-01

We propose a novel type of compact multichannel MEMS based spectrometer, where we replace the linear detector with a Digital Micromirror Device (DMD). The DMD is typically cheaper and has better pixel sampling than an InGaAs detector used in the 1550 nm range, which leads to cost reduction and better performance. Moreover, the DMD is a 2D array, which means that multichannel systems can be implemented without any additional optical components in the spectrometer. This makes the proposed interrogator highly cost-effective. The digital nature of the DMD also provides opportunities for advanced programmable spectroscopy.

A novel digital neutron flux monitor for international thermonuclear experimental reactor

NASA Astrophysics Data System (ADS)

Xiang, ZHOU; Zihao, LIU; Chao, CHEN; Renjie, ZHU; Li, ZHAO; Lingfeng, WEI; Zejie, YIN

2018-04-01

A novel full-digital real-time neutron flux monitor (NFM) has been developed for the International Thermonuclear Experimental Reactor. A measurement range of 109 counts per second is achieved with 3 different sensitive fission chambers. The Counting mode and Campbelling mode have been combined as a means to achieve higher measurement range. The system is based on high speed as well as parallel and pipeline processing of the field programmable gate array and has the ability to upload raw-data of analog-to-digital converter in real-time through the PXIe platform. With the advantages of the measurement range, real time performance and the ability of raw-data uploading, the digital NFM has been tested in HL-2A experiments and reflected good experimental performance.

Note: All-digital CMOS MOS-capacitor-based pulse-shrinking mechanism suitable for time-to-digital converters

NASA Astrophysics Data System (ADS)

Chen, Chun-Chi; Hwang, Chorng-Sii; Lin, You-Ting; Liu, Keng-Chih

2015-12-01

This paper presents an all-digital CMOS pulse-shrinking mechanism suitable for time-to-digital converters (TDCs). A simple MOS capacitor is used as a pulse-shrinking cell to perform time attenuation for time resolving. Compared with a previous pulse-shrinking mechanism, the proposed mechanism provides an appreciably improved temporal resolution with high linearity. Furthermore, the use of a binary-weighted pulse-shrinking unit with scaled MOS capacitors is proposed for achieving a programmable resolution. A TDC involving the proposed mechanism was fabricated using a TSMC (Taiwan Semiconductor Manufacturing Company) 0.18-μm CMOS process, and it has a small area of nearly 0.02 mm2 and an integral nonlinearity error of ±0.8 LSB for a resolution of 24 ps.

New digital capacitive measurement system for blade clearances

NASA Astrophysics Data System (ADS)

Moenich, Marcel; Bailleul, Gilles

This paper presents a totally new concept for tip blade clearance evaluation in turbine engines. This system is able to detect exact 'measurands' even under high temperature and severe conditions like ionization. The system is based on a heavy duty probe head, a miniaturized thick-film hybrid electronic circuit and a signal processing unit for real time computing. The high frequency individual measurement values are digitally filtered and linearized in real time. The electronic is built in hybrid technology and therefore can be kept extremely small and robust, so that the system can be used on actual flights.

Design of minimum multiplier fractional order differentiator based on lattice wave digital filter.

PubMed

Barsainya, Richa; Rawat, Tarun Kumar; Kumar, Manjeet

2017-01-01

In this paper, a novel design of fractional order differentiator (FOD) based on lattice wave digital filter (LWDF) is proposed which requires minimum number of multiplier for its structural realization. Firstly, the FOD design problem is formulated as an optimization problem using the transfer function of lattice wave digital filter. Then, three optimization algorithms, namely, genetic algorithm (GA), particle swarm optimization (PSO) and cuckoo search algorithm (CSA) are applied to determine the optimal LWDF coefficients. The realization of FOD using LWD structure increases the design accuracy, as only N number of coefficients are to be optimized for Nth order FOD. Finally, two design examples of 3rd and 5th order lattice wave digital fractional order differentiator (LWDFOD) are demonstrated to justify the design accuracy. The performance analysis of the proposed design is carried out based on magnitude response, absolute magnitude error (dB), root mean square (RMS) magnitude error, arithmetic complexity, convergence profile and computation time. Simulation results are attained to show the comparison of the proposed LWDFOD with the published works and it is observed that an improvement of 29% is obtained in the proposed design. The proposed LWDFOD approximates the ideal FOD and surpasses the existing ones reasonably well in mid and high frequency range, thereby making the proposed LWDFOD a promising technique for the design of digital FODs. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

Derivation of planetary topography using multi-image shape-from-shading

USGS Publications Warehouse

Lohse, V.; Heipke, C.; Kirk, R.L.

2006-01-01

In many cases, the derivation of high-resolution digital terrain models (DTMs) from planetary surfaces using conventional digital image matching is a problem. The matching methods need at least one stereo pair of images with sufficient texture. However, many space missions provide only a few stereo images and planetary surfaces often possess insufficient texture. This paper describes a method for the generation of high-resolution DTMs from planetary surfaces, which has the potential to overcome the described problem. The suggested method, developed by our group, is based on shape-from-shading using an arbitrary number of digital optical images, and is termed "multi-image shape-from-shading" (MI-SFS). The paper contains an explanation of the theory of MI-SFS, followed by a presentation of current results, which were obtained using images from NASA's lunar mission Clementine, and constitute the first practical application with our method using extraterrestrial imagery. The lunar surface is reconstructed under the assumption of different kinds of reflectance models (e.g. Lommel-Seeliger and Lambert). The represented results show that the derivation of a high-resolution DTM of real digital planetary images by means of MI-SFS is feasible. ?? 2006 Elsevier Ltd. All rights reserved.

The optimal digital filters of sine and cosine transforms for geophysical transient electromagnetic method

NASA Astrophysics Data System (ADS)

Zhao, Yun-wei; Zhu, Zi-qiang; Lu, Guang-yin; Han, Bo

2018-03-01

The sine and cosine transforms implemented with digital filters have been used in the Transient electromagnetic methods for a few decades. Kong (2007) proposed a method of obtaining filter coefficients, which are computed in the sample domain by Hankel transform pair. However, the curve shape of Hankel transform pair changes with a parameter, which usually is set to be 1 or 3 in the process of obtaining the digital filter coefficients of sine and cosine transforms. First, this study investigates the influence of the parameter on the digital filter algorithm of sine and cosine transforms based on the digital filter algorithm of Hankel transform and the relationship between the sine, cosine function and the ±1/2 order Bessel function of the first kind. The results show that the selection of the parameter highly influences the precision of digital filter algorithm. Second, upon the optimal selection of the parameter, it is found that an optimal sampling interval s also exists to achieve the best precision of digital filter algorithm. Finally, this study proposes four groups of sine and cosine transform digital filter coefficients with different length, which may help to develop the digital filter algorithm of sine and cosine transforms, and promote its application.

Cost-effective handling of digital medical images in the telemedicine environment.

PubMed

Choong, Miew Keen; Logeswaran, Rajasvaran; Bister, Michel

2007-09-01

This paper concentrates on strategies for less costly handling of medical images. Aspects of digitization using conventional digital cameras, lossy compression with good diagnostic quality, and visualization through less costly monitors are discussed. For digitization of film-based media, subjective evaluation of the suitability of digital cameras as an alternative to the digitizer was undertaken. To save on storage, bandwidth and transmission time, the acceptable degree of compression with diagnostically no loss of important data was studied through randomized double-blind tests of the subjective image quality when compression noise was kept lower than the inherent noise. A diagnostic experiment was undertaken to evaluate normal low cost computer monitors as viable viewing displays for clinicians. The results show that conventional digital camera images of X-ray images were diagnostically similar to the expensive digitizer. Lossy compression, when used moderately with the imaging noise to compression noise ratio (ICR) greater than four, can bring about image improvement with better diagnostic quality than the original image. Statistical analysis shows that there is no diagnostic difference between expensive high quality monitors and conventional computer monitors. The results presented show good potential in implementing the proposed strategies to promote widespread cost-effective telemedicine and digital medical environments. 2006 Elsevier Ireland Ltd

External validation of Medicare claims codes for digital mammography and computer-aided detection.

PubMed

Fenton, Joshua J; Zhu, Weiwei; Balch, Steven; Smith-Bindman, Rebecca; Lindfors, Karen K; Hubbard, Rebecca A

2012-08-01

While Medicare claims are a potential resource for clinical mammography research or quality monitoring, the validity of key data elements remains uncertain. Claims codes for digital mammography and computer-aided detection (CAD), for example, have not been validated against a credible external reference standard. We matched Medicare mammography claims for women who received bilateral mammograms from 2003 to 2006 to corresponding mammography data from the Breast Cancer Surveillance Consortium (BCSC) registries in four U.S. states (N = 253,727 mammograms received by 120,709 women). We assessed the accuracy of the claims-based classifications of bilateral mammograms as either digital versus film and CAD versus non-CAD relative to a reference standard derived from BCSC data. Claims data correctly classified the large majority of film and digital mammograms (97.2% and 97.3%, respectively), yielding excellent agreement beyond chance (κ = 0.90). Claims data correctly classified the large majority of CAD mammograms (96.6%) but a lower percentage of non-CAD mammograms (86.7%). Agreement beyond chance remained high for CAD classification (κ = 0.83). From 2003 to 2006, the predictive values of claims-based digital and CAD classifications increased as the sample prevalences of each technology increased. Medicare claims data can accurately distinguish film and digital bilateral mammograms and mammograms conducted with and without CAD. The validity of Medicare claims data regarding film versus digital mammography and CAD suggests that these data elements can be useful in research and quality improvement. ©2012 AACR.

CMOS-compatible 2-bit optical spectral quantization scheme using a silicon-nanocrystal-based horizontal slot waveguide

PubMed Central

Kang, Zhe; Yuan, Jinhui; Zhang, Xianting; Wu, Qiang; Sang, Xinzhu; Farrell, Gerald; Yu, Chongxiu; Li, Feng; Tam, Hwa Yaw; Wai, P. K. A.

2014-01-01

All-optical analog-to-digital converters based on the third-order nonlinear effects in silicon waveguide are a promising candidate to overcome the limitation of electronic devices and are suitable for photonic integration. In this paper, a 2-bit optical spectral quantization scheme for on-chip all-optical analog-to-digital conversion is proposed. The proposed scheme is realized by filtering the broadened and split spectrum induced by the self-phase modulation effect in a silicon horizontal slot waveguide filled with silicon-nanocrystal. Nonlinear coefficient as high as 8708 W−1/m is obtained because of the tight mode confinement of the horizontal slot waveguide and the high nonlinear refractive index of the silicon-nanocrystal, which provides the enhanced nonlinear interaction and accordingly low power threshold. The results show that a required input peak power level less than 0.4 W can be achieved, along with the 1.98-bit effective-number-of-bit and Gray code output. The proposed scheme can find important applications in on-chip all-optical digital signal processing systems. PMID:25417847

CMOS-compatible 2-bit optical spectral quantization scheme using a silicon-nanocrystal-based horizontal slot waveguide.

PubMed

Kang, Zhe; Yuan, Jinhui; Zhang, Xianting; Wu, Qiang; Sang, Xinzhu; Farrell, Gerald; Yu, Chongxiu; Li, Feng; Tam, Hwa Yaw; Wai, P K A

2014-11-24

All-optical analog-to-digital converters based on the third-order nonlinear effects in silicon waveguide are a promising candidate to overcome the limitation of electronic devices and are suitable for photonic integration. In this paper, a 2-bit optical spectral quantization scheme for on-chip all-optical analog-to-digital conversion is proposed. The proposed scheme is realized by filtering the broadened and split spectrum induced by the self-phase modulation effect in a silicon horizontal slot waveguide filled with silicon-nanocrystal. Nonlinear coefficient as high as 8708 W(-1)/m is obtained because of the tight mode confinement of the horizontal slot waveguide and the high nonlinear refractive index of the silicon-nanocrystal, which provides the enhanced nonlinear interaction and accordingly low power threshold. The results show that a required input peak power level less than 0.4 W can be achieved, along with the 1.98-bit effective-number-of-bit and Gray code output. The proposed scheme can find important applications in on-chip all-optical digital signal processing systems.

SU-F-T-20: Novel Catheter Lumen Recognition Algorithm for Rapid Digitization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dise, J; McDonald, D; Ashenafi, M

Purpose: Manual catheter recognition remains a time-consuming aspect of high-dose-rate brachytherapy (HDR) treatment planning. In this work, a novel catheter lumen recognition algorithm was created for accurate and rapid digitization. Methods: MatLab v8.5 was used to create the catheter recognition algorithm. Initially, the algorithm searches the patient CT dataset using an intensity based k-means filter designed to locate catheters. Once the catheters have been located, seed points are manually selected to initialize digitization of each catheter. From each seed point, the algorithm searches locally in order to automatically digitize the remaining catheter. This digitization is accomplished by finding pixels withmore » similar image curvature and divergence parameters compared to the seed pixel. Newly digitized pixels are treated as new seed positions, and hessian image analysis is used to direct the algorithm toward neighboring catheter pixels, and to make the algorithm insensitive to adjacent catheters that are unresolvable on CT, air pockets, and high Z artifacts. The algorithm was tested using 11 HDR treatment plans, including the Syed template, tandem and ovoid applicator, and multi-catheter lung brachytherapy. Digitization error was calculated by comparing manually determined catheter positions to those determined by the algorithm. Results: he digitization error was 0.23 mm ± 0.14 mm axially and 0.62 mm ± 0.13 mm longitudinally at the tip. The time of digitization, following initial seed placement was less than 1 second per catheter. The maximum total time required to digitize all tested applicators was 4 minutes (Syed template with 15 needles). Conclusion: This algorithm successfully digitizes HDR catheters for a variety of applicators with or without CT markers. The minimal axial error demonstrates the accuracy of the algorithm, and its insensitivity to image artifacts and challenging catheter positioning. Future work to automatically place initial seed positions would improve the algorithm speed.« less

Detection of regional air pollution episodes utilizing satellite digital data in the visual range

NASA Technical Reports Server (NTRS)

Burke, H.-H. K.

1982-01-01

Digital analyses of satellite visible data for selected high-sulfate cases over the northeastern U.S., on July 21 and 22, 1978, are compared with ground-based measurements. Quantitative information on total aerosol loading derived from the satellite digitized data using an atmospheric radiative transfer model is found to agree with the ground measurements, and it is shown that the extent and transport of the haze pattern may be monitored from the satellite data over the period of maximum intensity for the episode. Attention is drawn to the potential benefits of satellite monitoring of pollution episodes demonstrated by the model.

From Geocentrism to Allocentrism: Teaching the Phases of the Moon in a Digital Full-Dome Planetarium

NASA Astrophysics Data System (ADS)

Chastenay, Pierre

2016-02-01

An increasing number of planetariums worldwide are turning digital, using ultra-fast computers, powerful graphic cards, and high-resolution video projectors to create highly realistic astronomical imagery in real time. This modern technology makes it so that the audience can observe astronomical phenomena from a geocentric as well as an allocentric perspective (the view from space). While the dome creates a sense of immersion, the digital planetarium introduces a new way to teach astronomy, especially for topics that are inherently three-dimensional and where seeing the phenomenon from different points of view is essential. Like a virtual-reality environment, an immersive digital planetarium helps learners create a more scientifically accurate visualization of astronomical phenomena. In this study, a digital planetarium was used to teach the phases of the Moon to children aged 12 to 14. To fully grasp the lunar phases, one must imagine the spherical Moon (as perceived from space), revolving around the Earth while being illuminated by the Sun, and then reconcile this view with the geocentric perspective. Digital planetariums allow learners to have both an allocentric and a geocentric perspective on the lunar phases. Using a Design experiment approach, we tested an educational scenario in which the lunar phases were taught in an allocentric digital planetarium. Based on qualitative data collected before, during, and after the planetarium intervention, we were able to demonstrate that five out of six participants had a better understanding of the lunar phases after the planetarium session.

The Digital Fish Library: Using MRI to Digitize, Database, and Document the Morphological Diversity of Fish

PubMed Central

Berquist, Rachel M.; Gledhill, Kristen M.; Peterson, Matthew W.; Doan, Allyson H.; Baxter, Gregory T.; Yopak, Kara E.; Kang, Ning; Walker, H. J.; Hastings, Philip A.; Frank, Lawrence R.

2012-01-01

Museum fish collections possess a wealth of anatomical and morphological data that are essential for documenting and understanding biodiversity. Obtaining access to specimens for research, however, is not always practical and frequently conflicts with the need to maintain the physical integrity of specimens and the collection as a whole. Non-invasive three-dimensional (3D) digital imaging therefore serves a critical role in facilitating the digitization of these specimens for anatomical and morphological analysis as well as facilitating an efficient method for online storage and sharing of this imaging data. Here we describe the development of the Digital Fish Library (DFL, http://www.digitalfishlibrary.org), an online digital archive of high-resolution, high-contrast, magnetic resonance imaging (MRI) scans of the soft tissue anatomy of an array of fishes preserved in the Marine Vertebrate Collection of Scripps Institution of Oceanography. We have imaged and uploaded MRI data for over 300 marine and freshwater species, developed a data archival and retrieval system with a web-based image analysis and visualization tool, and integrated these into the public DFL website to disseminate data and associated metadata freely over the web. We show that MRI is a rapid and powerful method for accurately depicting the in-situ soft-tissue anatomy of preserved fishes in sufficient detail for large-scale comparative digital morphology. However these 3D volumetric data require a sophisticated computational and archival infrastructure in order to be broadly accessible to researchers and educators. PMID:22493695

An automated system for whole microscopic image acquisition and analysis.

PubMed

Bueno, Gloria; Déniz, Oscar; Fernández-Carrobles, María Del Milagro; Vállez, Noelia; Salido, Jesús

2014-09-01

The field of anatomic pathology has experienced major changes over the last decade. Virtual microscopy (VM) systems have allowed experts in pathology and other biomedical areas to work in a safer and more collaborative way. VMs are automated systems capable of digitizing microscopic samples that were traditionally examined one by one. The possibility of having digital copies reduces the risk of damaging original samples, and also makes it easier to distribute copies among other pathologists. This article describes the development of an automated high-resolution whole slide imaging (WSI) system tailored to the needs and problems encountered in digital imaging for pathology, from hardware control to the full digitization of samples. The system has been built with an additional digital monochromatic camera together with the color camera by default and LED transmitted illumination (RGB). Monochrome cameras are the preferred method of acquisition for fluorescence microscopy. The system is able to digitize correctly and form large high resolution microscope images for both brightfield and fluorescence. The quality of the digital images has been quantified using three metrics based on sharpness, contrast and focus. It has been proved on 150 tissue samples of brain autopsies, prostate biopsies and lung cytologies, at five magnifications: 2.5×, 10×, 20×, 40×, and 63×. The article is focused on the hardware set-up and the acquisition software, although results of the implemented image processing techniques included in the software and applied to the different tissue samples are also presented. © 2014 Wiley Periodicals, Inc.

The Digital Fish Library: using MRI to digitize, database, and document the morphological diversity of fish.

PubMed

Berquist, Rachel M; Gledhill, Kristen M; Peterson, Matthew W; Doan, Allyson H; Baxter, Gregory T; Yopak, Kara E; Kang, Ning; Walker, H J; Hastings, Philip A; Frank, Lawrence R

2012-01-01

Museum fish collections possess a wealth of anatomical and morphological data that are essential for documenting and understanding biodiversity. Obtaining access to specimens for research, however, is not always practical and frequently conflicts with the need to maintain the physical integrity of specimens and the collection as a whole. Non-invasive three-dimensional (3D) digital imaging therefore serves a critical role in facilitating the digitization of these specimens for anatomical and morphological analysis as well as facilitating an efficient method for online storage and sharing of this imaging data. Here we describe the development of the Digital Fish Library (DFL, http://www.digitalfishlibrary.org), an online digital archive of high-resolution, high-contrast, magnetic resonance imaging (MRI) scans of the soft tissue anatomy of an array of fishes preserved in the Marine Vertebrate Collection of Scripps Institution of Oceanography. We have imaged and uploaded MRI data for over 300 marine and freshwater species, developed a data archival and retrieval system with a web-based image analysis and visualization tool, and integrated these into the public DFL website to disseminate data and associated metadata freely over the web. We show that MRI is a rapid and powerful method for accurately depicting the in-situ soft-tissue anatomy of preserved fishes in sufficient detail for large-scale comparative digital morphology. However these 3D volumetric data require a sophisticated computational and archival infrastructure in order to be broadly accessible to researchers and educators.

A novel PMT test system based on waveform sampling

NASA Astrophysics Data System (ADS)

Yin, S.; Ma, L.; Ning, Z.; Qian, S.; Wang, Y.; Jiang, X.; Wang, Z.; Yu, B.; Gao, F.; Zhu, Y.; Wang, Z.

2018-01-01

Comparing with the traditional test system based on a QDC and TDC and scaler, a test system based on waveform sampling is constructed for signal sampling of the 8"R5912 and the 20"R12860 Hamamatsu PMT in different energy states from single to multiple photoelectrons. In order to achieve high throughput and to reduce the dead time in data processing, the data acquisition software based on LabVIEW is developed and runs with a parallel mechanism. The analysis algorithm is realized in LabVIEW and the spectra of charge, amplitude, signal width and rising time are analyzed offline. The results from Charge-to-Digital Converter, Time-to-Digital Converter and waveform sampling are discussed in detailed comparison.

Evaluation of the capabilities of satellite imagery for monitoring regional air pollution episodes

NASA Technical Reports Server (NTRS)

Barnes, J. C.; Bowley, C. J.; Burke, H. H. K.

1979-01-01

A comparative analysis of satellite visible channel imagery and ground based aerosol measurements is carried out for three cases representing a significant pollution episodes based on low surface visibility and high sulfate levels. The feasibility of detecting pollution episodes from space is also investigated using a simulation model. The model results are compared to quantitative information derived from digitized satellite data. The results show that when levels are or = 30 micrograms/cu, a haze pattern that correlates closely with the area of reported low surface visibilities and high micrograms sulfate levels can be detected in satellite visible channel imagery. The model simulation demonstrates the potential of the satellite to monitor the magnitude and areal extent of pollution episodes. Quantitative information on total aerosol amount derived from the satellite digitized data using the atmospheric radiative transfer model agrees well with the results obtained from the ground based measurements.

Snow survey and vegetation growth in high mountains (Swiss Alps) and additional ERTS investigations in Switzerland

NASA Technical Reports Server (NTRS)

Haefner, H. (Principal Investigator)

1975-01-01

The author has identified the following significant results. Two different methods, an analog and a digital one, have been developed for rapid and accurate mapping of the areal extent and changes in snow cover in high mountains. The quick-look method is based on individual visual control of each image using a photo quantizer which provides exact references for density slicing with high resolution lith-film. The digital snow classification system is based on discriminant analysis with the data of the four multispectral bands as variables and contains all preprocessing, feature extraction, and mapping steps for an operational application. Two different sets of sampling groups were established which apply to different conditions of snow cover. The first one serves for the normal situation with a uniform dry and new cover. The second one serves for situations with partly thawing and/or frozen snow.

A fast low-power optical memory based on coupled micro-ring lasers

NASA Astrophysics Data System (ADS)

Hill, Martin T.; Dorren, Harmen J. S.; de Vries, Tjibbe; Leijtens, Xaveer J. M.; den Besten, Jan Hendrik; Smalbrugge, Barry; Oei, Yok-Siang; Binsma, Hans; Khoe, Giok-Djan; Smit, Meint K.

2004-11-01

The increasing speed of fibre-optic-based telecommunications has focused attention on high-speed optical processing of digital information. Complex optical processing requires a high-density, high-speed, low-power optical memory that can be integrated with planar semiconductor technology for buffering of decisions and telecommunication data. Recently, ring lasers with extremely small size and low operating power have been made, and we demonstrate here a memory element constructed by interconnecting these microscopic lasers. Our device occupies an area of 18 × 40µm2 on an InP/InGaAsP photonic integrated circuit, and switches within 20ps with 5.5fJ optical switching energy. Simulations show that the element has the potential for much smaller dimensions and switching times. Large numbers of such memory elements can be densely integrated and interconnected on a photonic integrated circuit: fast digital optical information processing systems employing large-scale integration should now be viable.

High-resolution terahertz inline digital holography based on quantum cascade laser

NASA Astrophysics Data System (ADS)

Deng, Qinghua; Li, Weihua; Wang, Xuemin; Li, Zeyu; Huang, Haochong; Shen, Changle; Zhan, Zhiqiang; Zou, Ruijiao; Jiang, Tao; Wu, Weidong

2017-11-01

A key requirement to put terahertz (THz) imaging systems into applications is high resolution. Based on a self-developed THz quantum cascade laser (QCL), we demonstrate a THz inline digital holography imaging system with high lateral resolution. In our case, the lateral resolution of this holography imaging system is pushed to about 70 μm, which is close to the intrinsic resolution limit of this system. To the best of our knowledge, this is much smaller than what has been reported up to now. This is attributed to a series of improvements, such as shortening the QCL wavelength, increasing Nx and Ny by the synthetic aperture method, smoothing the source beam profile, and diminishing vibration due to the cryorefrigeration device. This kind of holography system with a resolution smaller than 100 μm opens the door for many imaging experiments. It will turn the THz imaging systems into applications.

Precise color images a high-speed color video camera system with three intensified sensors

NASA Astrophysics Data System (ADS)

Oki, Sachio; Yamakawa, Masafumi; Gohda, Susumu; Etoh, Takeharu G.

1999-06-01

High speed imaging systems have been used in a large field of science and engineering. Although the high speed camera systems have been improved to high performance, most of their applications are only to get high speed motion pictures. However, in some fields of science and technology, it is useful to get some other information, such as temperature of combustion flame, thermal plasma and molten materials. Recent digital high speed video imaging technology should be able to get such information from those objects. For this purpose, we have already developed a high speed video camera system with three-intensified-sensors and cubic prism image splitter. The maximum frame rate is 40,500 pps (picture per second) at 64 X 64 pixels and 4,500 pps at 256 X 256 pixels with 256 (8 bit) intensity resolution for each pixel. The camera system can store more than 1,000 pictures continuously in solid state memory. In order to get the precise color images from this camera system, we need to develop a digital technique, which consists of a computer program and ancillary instruments, to adjust displacement of images taken from two or three image sensors and to calibrate relationship between incident light intensity and corresponding digital output signals. In this paper, the digital technique for pixel-based displacement adjustment are proposed. Although the displacement of the corresponding circle was more than 8 pixels in original image, the displacement was adjusted within 0.2 pixels at most by this method.

A high performance cost-effective digital complex correlator for an X-band polarimetry survey.

PubMed

Bergano, Miguel; Rocha, Armando; Cupido, Luís; Barbosa, Domingos; Villela, Thyrso; Boas, José Vilas; Rocha, Graça; Smoot, George F

2016-01-01

The detailed knowledge of the Milky Way radio emission is important to characterize galactic foregrounds masking extragalactic and cosmological signals. The update of the global sky models describing radio emissions over a very large spectral band requires high sensitivity experiments capable of observing large sky areas with long integration times. Here, we present the design of a new 10 GHz (X-band) polarimeter digital back-end to map the polarization components of the galactic synchrotron radiation field of the Northern Hemisphere sky. The design follows the digital processing trends in radio astronomy and implements a large bandwidth (1 GHz) digital complex cross-correlator to extract the Stokes parameters of the incoming synchrotron radiation field. The hardware constraints cover the implemented VLSI hardware description language code and the preliminary results. The implementation is based on the simultaneous digitized acquisition of the Cartesian components of the two linear receiver polarization channels. The design strategy involves a double data rate acquisition of the ADC interleaved parallel bus, and field programmable gate array device programming at the register transfer mode. The digital core of the back-end is capable of processing 32 Gbps and is built around an Altera field programmable gate array clocked at 250 MHz, 1 GSps analog to digital converters and a clock generator. The control of the field programmable gate array internal signal delays and a convenient use of its phase locked loops provide the timing requirements to achieve the target bandwidths and sensitivity. This solution is convenient for radio astronomy experiments requiring large bandwidth, high functionality, high volume availability and low cost. Of particular interest, this correlator was developed for the Galactic Emission Mapping project and is suitable for large sky area polarization continuum surveys. The solutions may also be adapted to be used at signal processing subsystem levels for large projects like the square kilometer array testbeds.

A low-cost, scalable, current-sensing digital headstage for high channel count μECoG.

PubMed

Trumpis, Michael; Insanally, Michele; Zou, Jialin; Elsharif, Ashraf; Ghomashchi, Ali; Sertac Artan, N; Froemke, Robert C; Viventi, Jonathan

2017-04-01

High channel count electrode arrays allow for the monitoring of large-scale neural activity at high spatial resolution. Implantable arrays featuring many recording sites require compact, high bandwidth front-end electronics. In the present study, we investigated the use of a small, light weight, and low cost digital current-sensing integrated circuit for acquiring cortical surface signals from a 61-channel micro-electrocorticographic (μECoG) array. We recorded both acute and chronic μECoG signal from rat auditory cortex using our novel digital current-sensing headstage. For direct comparison, separate recordings were made in the same anesthetized preparations using an analog voltage headstage. A model of electrode impedance explained the transformation between current- and voltage-sensed signals, and was used to reconstruct cortical potential. We evaluated the digital headstage using several metrics of the baseline and response signals. The digital current headstage recorded neural signal with similar spatiotemporal statistics and auditory frequency tuning compared to the voltage signal. The signal-to-noise ratio of auditory evoked responses (AERs) was significantly stronger in the current signal. Stimulus decoding based on true and reconstructed voltage signals were not significantly different. Recordings from an implanted system showed AERs that were detectable and decodable for 52 d. The reconstruction filter mitigated the thermal current noise of the electrode impedance and enhanced overall SNR. We developed and validated a novel approach to headstage acquisition that used current-input circuits to independently digitize 61 channels of μECoG measurements of the cortical field. These low-cost circuits, intended to measure photo-currents in digital imaging, not only provided a signal representing the local cortical field with virtually the same sensitivity and specificity as a traditional voltage headstage but also resulted in a small, light headstage that can easily be scaled to record from hundreds of channels.

A low-cost, scalable, current-sensing digital headstage for high channel count μECoG

NASA Astrophysics Data System (ADS)

Trumpis, Michael; Insanally, Michele; Zou, Jialin; Elsharif, Ashraf; Ghomashchi, Ali; Sertac Artan, N.; Froemke, Robert C.; Viventi, Jonathan

2017-04-01

Objective. High channel count electrode arrays allow for the monitoring of large-scale neural activity at high spatial resolution. Implantable arrays featuring many recording sites require compact, high bandwidth front-end electronics. In the present study, we investigated the use of a small, light weight, and low cost digital current-sensing integrated circuit for acquiring cortical surface signals from a 61-channel micro-electrocorticographic (μECoG) array. Approach. We recorded both acute and chronic μECoG signal from rat auditory cortex using our novel digital current-sensing headstage. For direct comparison, separate recordings were made in the same anesthetized preparations using an analog voltage headstage. A model of electrode impedance explained the transformation between current- and voltage-sensed signals, and was used to reconstruct cortical potential. We evaluated the digital headstage using several metrics of the baseline and response signals. Main results. The digital current headstage recorded neural signal with similar spatiotemporal statistics and auditory frequency tuning compared to the voltage signal. The signal-to-noise ratio of auditory evoked responses (AERs) was significantly stronger in the current signal. Stimulus decoding based on true and reconstructed voltage signals were not significantly different. Recordings from an implanted system showed AERs that were detectable and decodable for 52 d. The reconstruction filter mitigated the thermal current noise of the electrode impedance and enhanced overall SNR. Significance. We developed and validated a novel approach to headstage acquisition that used current-input circuits to independently digitize 61 channels of μECoG measurements of the cortical field. These low-cost circuits, intended to measure photo-currents in digital imaging, not only provided a signal representing the local cortical field with virtually the same sensitivity and specificity as a traditional voltage headstage but also resulted in a small, light headstage that can easily be scaled to record from hundreds of channels.

A low-cost, scalable, current-sensing digital headstage for high channel count μECoG

PubMed Central

Trumpis, Michael; Insanally, Michele; Zou, Jialin; Elsharif, Ashraf; Ghomashchi, Ali; Artan, N. Sertac; Froemke, Robert C.; Viventi, Jonathan

2017-01-01

Objective High channel count electrode arrays allow for the monitoring of large-scale neural activity at high spatial resolution. Implantable arrays featuring many recording sites require compact, high bandwidth front-end electronics. In the present study, we investigated the use of a small, light weight, and low cost digital current-sensing integrated circuit for acquiring cortical surface signals from a 61-channel micro-electrocorticographic (μECoG) array. Approach We recorded both acute and chronic μECoG signal from rat auditory cortex using our novel digital current-sensing headstage. For direct comparison, separate recordings were made in the same anesthetized preparations using an analog voltage headstage. A model of electrode impedance explained the transformation between current- and voltage-sensed signals, and was used to reconstruct cortical potential. We evaluated the digital headstage using several metrics of the baseline and response signals. Main results The digital current headstage recorded neural signal with similar spatiotemporal statistics and auditory frequency tuning compared to the voltage signal. The signal-to-noise ratio of auditory evoked responses (AERs) was significantly stronger in the current signal. Stimulus decoding based on true and reconstructed voltage signals were not significantly different. Recordings from an implanted system showed AERs that were detectable and decodable for 52 days. The reconstruction filter mitigated the thermal current noise of the electrode impedance and enhanced overall SNR. Significance We developed and validated a novel approach to headstage acquisition that used current-input circuits to independently digitize 61 channels of μECoG measurements of the cortical field. These low-cost circuits, intended to measure photo-currents in digital imaging, not only provided a signal representing the local cortical field with virtually the same sensitivity and specificity as a traditional voltage headstage but also resulted in a small, light headstage that can easily be scaled to record from hundreds of channels. PMID:28102827

Wideband digital frequency detector with subtraction-based phase comparator for frequency modulation atomic force microscopy.

PubMed

Mitani, Yuji; Kubo, Mamoru; Muramoto, Ken-ichiro; Fukuma, Takeshi

2009-08-01

We have developed a wideband digital frequency detector for high-speed frequency modulation atomic force microscopy (FM-AFM). We used a subtraction-based phase comparator (PC) in a phase-locked loop circuit instead of a commonly used multiplication-based PC, which has enhanced the detection bandwidth to 100 kHz. The quantitative analysis of the noise performance revealed that the internal noise from the developed detector is small enough to provide the theoretically limited noise performance in FM-AFM experiments in liquid. FM-AFM imaging of mica in liquid was performed with the developed detector, showing its stability and applicability to true atomic-resolution imaging in liquid.

Development of a digital microfluidic platform for point of care testing

PubMed Central

Sista, Ramakrishna; Hua, Zhishan; Thwar, Prasanna; Sudarsan, Arjun; Srinivasan, Vijay; Eckhardt, Allen; Pollack, Michael; Pamula, Vamsee

2009-01-01

Point of care testing is playing an increasingly important role in improving the clinical outcome in health care management. The salient features of a point of care device are quick results, integrated sample preparation and processing, small sample volumes, portability, multifunctionality and low cost. In this paper, we demonstrate some of these salient features utilizing an electrowetting-based Digital Microfluidic platform. We demonstrate the performance of magnetic bead-based immunoassays (cardiac troponin I) on a digital microfluidic cartridge in less than 8 minutes using whole blood samples. Using the same microfluidic cartridge, a 40-cycle real-time polymerase chain reaction was performed within 12 minutes by shuttling a droplet between two thermal zones. We further demonstrate, on the same cartridge, the capability to perform sample preparation for bacterial and fungal infectious disease pathogens (methicillin-resistance Staphylococcus aureus and Candida albicans) and for human genomic DNA using magnetic beads. In addition to rapid results and integrated sample preparation, electrowetting-based digital microfluidic instruments are highly portable because fluid pumping is performed electronically. All the digital microfluidic chips presented here were fabricated on printed circuit boards utilizing mass production techniques that keep the cost of the chip low. Due to the modularity and scalability afforded by digital microfluidics, multifunctional testing capability, such as combinations within and between immunoassays, DNA amplification, and enzymatic assays, can be brought to the point of care at a relatively low cost because a single chip can be configured in software for different assays required along the path of care. PMID:19023472

Differential high-speed digital micromirror device based fluorescence speckle confocal microscopy.

PubMed

Jiang, Shihong; Walker, John

2010-01-20

We report a differential fluorescence speckle confocal microscope that acquires an image in a fraction of a second by exploiting the very high frame rate of modern digital micromirror devices (DMDs). The DMD projects a sequence of predefined binary speckle patterns to the sample and modulates the intensity of the returning fluorescent light simultaneously. The fluorescent light reflecting from the DMD's "on" and "off" pixels is modulated by correlated speckle and anticorrelated speckle, respectively, to form two images on two CCD cameras in parallel. The sum of the two images recovers a widefield image, but their difference gives a near-confocal image in real time. Experimental results for both low and high numerical apertures are shown.

Point-of-care mobile digital microscopy and deep learning for the detection of soil-transmitted helminths and Schistosoma haematobium.

PubMed

Holmström, Oscar; Linder, Nina; Ngasala, Billy; Mårtensson, Andreas; Linder, Ewert; Lundin, Mikael; Moilanen, Hannu; Suutala, Antti; Diwan, Vinod; Lundin, Johan

2017-06-01

Microscopy remains the gold standard in the diagnosis of neglected tropical diseases. As resource limited, rural areas often lack laboratory equipment and trained personnel, new diagnostic techniques are needed. Low-cost, point-of-care imaging devices show potential in the diagnosis of these diseases. Novel, digital image analysis algorithms can be utilized to automate sample analysis. Evaluation of the imaging performance of a miniature digital microscopy scanner for the diagnosis of soil-transmitted helminths and Schistosoma haematobium, and training of a deep learning-based image analysis algorithm for automated detection of soil-transmitted helminths in the captured images. A total of 13 iodine-stained stool samples containing Ascaris lumbricoides, Trichuris trichiura and hookworm eggs and 4 urine samples containing Schistosoma haematobium were digitized using a reference whole slide-scanner and the mobile microscopy scanner. Parasites in the images were identified by visual examination and by analysis with a deep learning-based image analysis algorithm in the stool samples. Results were compared between the digital and visual analysis of the images showing helminth eggs. Parasite identification by visual analysis of digital slides captured with the mobile microscope was feasible for all analyzed parasites. Although the spatial resolution of the reference slide-scanner is higher, the resolution of the mobile microscope is sufficient for reliable identification and classification of all parasites studied. Digital image analysis of stool sample images captured with the mobile microscope showed high sensitivity for detection of all helminths studied (range of sensitivity = 83.3-100%) in the test set (n = 217) of manually labeled helminth eggs. In this proof-of-concept study, the imaging performance of a mobile, digital microscope was sufficient for visual detection of soil-transmitted helminths and Schistosoma haematobium. Furthermore, we show that deep learning-based image analysis can be utilized for the automated detection and classification of helminths in the captured images.

Point-of-care mobile digital microscopy and deep learning for the detection of soil-transmitted helminths and Schistosoma haematobium

PubMed Central

Holmström, Oscar; Linder, Nina; Ngasala, Billy; Mårtensson, Andreas; Linder, Ewert; Lundin, Mikael; Moilanen, Hannu; Suutala, Antti; Diwan, Vinod; Lundin, Johan

2017-01-01

ABSTRACT Background: Microscopy remains the gold standard in the diagnosis of neglected tropical diseases. As resource limited, rural areas often lack laboratory equipment and trained personnel, new diagnostic techniques are needed. Low-cost, point-of-care imaging devices show potential in the diagnosis of these diseases. Novel, digital image analysis algorithms can be utilized to automate sample analysis. Objective: Evaluation of the imaging performance of a miniature digital microscopy scanner for the diagnosis of soil-transmitted helminths and Schistosoma haematobium, and training of a deep learning-based image analysis algorithm for automated detection of soil-transmitted helminths in the captured images. Methods: A total of 13 iodine-stained stool samples containing Ascaris lumbricoides, Trichuris trichiura and hookworm eggs and 4 urine samples containing Schistosoma haematobium were digitized using a reference whole slide-scanner and the mobile microscopy scanner. Parasites in the images were identified by visual examination and by analysis with a deep learning-based image analysis algorithm in the stool samples. Results were compared between the digital and visual analysis of the images showing helminth eggs. Results: Parasite identification by visual analysis of digital slides captured with the mobile microscope was feasible for all analyzed parasites. Although the spatial resolution of the reference slide-scanner is higher, the resolution of the mobile microscope is sufficient for reliable identification and classification of all parasites studied. Digital image analysis of stool sample images captured with the mobile microscope showed high sensitivity for detection of all helminths studied (range of sensitivity = 83.3–100%) in the test set (n = 217) of manually labeled helminth eggs. Conclusions: In this proof-of-concept study, the imaging performance of a mobile, digital microscope was sufficient for visual detection of soil-transmitted helminths and Schistosoma haematobium. Furthermore, we show that deep learning-based image analysis can be utilized for the automated detection and classification of helminths in the captured images. PMID:28838305

Generation of multiple analog pulses with different duty cycles within VME control system for ICRH Aditya system

NASA Astrophysics Data System (ADS)

Joshi, Ramesh; Singh, Manoj; Jadav, H. M.; Misra, Kishor; Kulkarni, S. V.; ICRH-RF Group

2010-02-01

Ion Cyclotron Resonance Heating (ICRH) is a promising heating method for a fusion device due to its localized power deposition profile, a direct ion heating at high density, and established technology for high RF power generation and transmission at low cost. Multiple analog pulse with different duty cycle in master of digital pulse for Data acquisition and Control system for steady state RF ICRH System(RF ICRH DAC) to be used for operating of RF Generator in Aditya to produce pre ionization and second analog pulse will produce heating. The control system software is based upon single digital pulse operation for RF source. It is planned to integrate multiple analog pulses with different duty cycle in master of digital pulse for Data acquisition and Control system for RF ICRH System(RF ICRH DAC) to be used for operating of RF Generator in Aditya tokamak. The task of RF ICRH DAC is to control and acquisition of all ICRH system operation with all control loop and acquisition for post analysis of data with java based tool. For pre ionization startup as well as heating experiments using multiple RF Power of different powers and duration. The experiment based upon the idea of using single RF generator to energize antenna inside the tokamak to radiate power twise, out of which first analog pulse will produce pre ionization and second analog pulse will produce heating. The whole system is based on standard client server technology using tcp/ip protocol. DAC Software is based on linux operating system for highly reliable, secure and stable system operation in failsafe manner. Client system is based on tcl/tk like toolkit for user interface with c/c++ like environment which is reliable programming languages widely used on stand alone system operation with server as vxWorks real time operating system like environment. The paper is focused on the Data acquisition and monitoring system software on Aditya RF ICRH System with analog pulses in slave mode with digital pulse in master mode for control acquisition and monitoring and interlocking.

Method and apparatus for data sampling

DOEpatents

Odell, Daniel M. C.

1994-01-01

A method and apparatus for sampling radiation detector outputs and determining event data from the collected samples. The method uses high speed sampling of the detector output, the conversion of the samples to digital values, and the discrimination of the digital values so that digital values representing detected events are determined. The high speed sampling and digital conversion is performed by an A/D sampler that samples the detector output at a rate high enough to produce numerous digital samples for each detected event. The digital discrimination identifies those digital samples that are not representative of detected events. The sampling and discrimination also provides for temporary or permanent storage, either serially or in parallel, to a digital storage medium.

Sensitivity and specificity of digital retinal imaging for screening diabetic retinopathy.

PubMed

Lopez-Bastida, J; Cabrera-Lopez, F; Serrano-Aguilar, P

2007-04-01

To assess the effectiveness of a non-mydriatic digital camera (45 degrees -30 degrees photographs) compared with the reference method for screening diabetic retinopathy. Type 1 and 2 diabetic patients (n = 773; 1546 eyes) underwent screening for diabetic retinopathy in a prospective observational study. Hospital-based non-mydriatic digital retinal imaging by a consultant specialist in retinal diseases was compared with slit-lamp biomicroscopy and indirect ophthalmoscopy through dilated pupils, as a gold standard, previously performed in a community health centre by another consultant specialist in retinal diseases. The main outcome measures were sensitivity and specificity of screening methods and prevalence of diabetic retinopathy. The prevalence of any form of diabetic retinopathy was 42.4% (n = 328); the prevalence of sight-threatening including macular oedema and proliferative retinopathy was 9.6% (n = 74). Sensitivity of detection of any diabetic retinopathy by digital imaging was 92% (95% confidence interval 90, 94). Specificity of detection of any diabetic retinopathy was 96% (95, 98). The predictive value of the negative tests was 94% and of a positive test 95%. For sight-threatening retinopathy digital imaging had a sensitivity of 100%. A high sensitivity and specificity are essential for an effective screening programme. These results confirm digital retinal imaging with a non-mydriatic camera as an effective option in community-based screening programmes for diabetic retinopathy.

Digital versus film stereo-photography for assessment of the optic nerve head in glaucoma and glaucoma suspect patients.

PubMed

Hasanreisoglu, Murat; Priel, Ethan; Naveh, Lili; Lusky, Moshe; Weinberger, Dov; Benjamini, Yoav; Gaton, Dan D

2013-03-01

One of the leading methods for optic nerve head assessment in glaucoma remains stereoscopic photography. This study compared conventional film and digital stereoscopy in the quantitative and qualitative assessment of the optic nerve head in glaucoma and glaucoma suspect patients. Fifty patients with glaucoma or suspected glaucoma underwent stereoscopic photography of the optic nerve head with a 35-mm color slide film and a digital camera. Photographs/images were presented in random order to 3 glaucoma specialists for independent analysis using a standardized assessment form. Findings for the following parameters were compared among assessors and between techniques: cup/disc (C/D) ratio, state of the optic rim, presence of peripapillary atrophy and appearance of the retinal nerve fiber layer, blood vessels, and lamina cribrosa. The film-based and image-based diagnoses (glaucoma yes/no) were compared as well. Despite high level of agreement across graders using the same method for the horizontal and vertical C/D ratio, (intraclass correlations 0.80 to 0.83), the agreement across graders was much lower for the other parameters using the same method. Similarly the agreement between the findings of the same grader using either method was high for horizontal and vertical C/D ratio, but low for the other parameters. The latter differences were reflected in the disagreement regarding the final diagnosis: The diagnoses differed by technique for each grader in 18% to 46% of eyes, resulting in 38.5% of eyes diagnosed with glaucoma by film photography that "lost" their diagnosis on the digital images, whereas 18.7% of eyes diagnosed as nonglaucomatous by film photography were considered to have glaucoma on the digital images. Although there is consistency between 35-mm film stereoscopy and digital stereoscopy in determining the cup/disc (C/D) ratio, in all other parameters large differences exist, leading to differences in diagnosis. Differences in capturing images between digital and film photography may lead to loss of information and misdiagnosis. Further studies are needed to determine the reliability of the new digital techniques.

Digital disaster evaluation and its application to 2015 Ms 8.1 Nepal Earthquake

NASA Astrophysics Data System (ADS)

WANG, Xiaoqing; LV, Jinxia; DING, Xiang; DOU, Aixia

2016-11-01

The purpose of the article is to probe the technique resolution of disaster information extraction and evaluation from the digital RS images based on the internet environment and aided by the social and geographic information. The solution is composed with such methods that the fast post-disaster assessment system will assess automatically the disaster area and grade, the multi-phase satellite and airborne high resolution digital RS images will provide the basis to extract the disaster areas or spots, assisted by the fast position of potential serious damage risk targets according to the geographic, administrative, population, buildings and other information in the estimated disaster region, the 2D digital map system or 3D digital earth system will provide platforms to interpret cooperatively the damage information in the internet environment, and further to estimate the spatial distribution of damage index or intensity, casualties or economic losses, which are very useful for the decision-making of emergency rescue and disaster relief, resettlement and reconstruction. The spatial seismic damage distribution of 2015 Ms 8.1 Nepal earthquake, as an example of the above solution, is evaluated by using the high resolution digital RS images, auxiliary geographic information and ground survey. The results are compared with the statistical disaster information issued by the ground truth by field surveying, and show good consistency.

Smartphone based scalable reverse engineering by digital image correlation

NASA Astrophysics Data System (ADS)

Vidvans, Amey; Basu, Saurabh

2018-03-01

There is a need for scalable open source 3D reconstruction systems for reverse engineering. This is because most commercially available reconstruction systems are capital and resource intensive. To address this, a novel reconstruction technique is proposed. The technique involves digital image correlation based characterization of surface speeds followed by normalization with respect to angular speed during rigid body rotational motion of the specimen. Proof of concept of the same is demonstrated and validated using simulation and empirical characterization. Towards this, smart-phone imaging and inexpensive off the shelf components along with those fabricated additively using poly-lactic acid polymer with a standard 3D printer are used. Some sources of error in this reconstruction methodology are discussed. It is seen that high curvatures on the surface suppress accuracy of reconstruction. Reasons behind this are delineated in the nature of the correlation function. Theoretically achievable resolution during smart-phone based 3D reconstruction by digital image correlation is derived.

FPGA design of correlation-based pattern recognition

NASA Astrophysics Data System (ADS)

Jridi, Maher; Alfalou, Ayman

2017-05-01

Optical/Digital pattern recognition and tracking based on optical/digital correlation are a well-known techniques to detect, identify and localize a target object in a scene. Despite the limited number of treatments required by the correlation scheme, computational time and resources are relatively high. The most computational intensive treatment required by the correlation is the transformation from spatial to spectral domain and then from spectral to spatial domain. Furthermore, these transformations are used on optical/digital encryption schemes like the double random phase encryption (DRPE). In this paper, we present a VLSI architecture for the correlation scheme based on the fast Fourier transform (FFT). One interesting feature of the proposed scheme is its ability to stream image processing in order to perform correlation for video sequences. A trade-off between the hardware consumption and the robustness of the correlation can be made in order to understand the limitations of the correlation implementation in reconfigurable and portable platforms. Experimental results obtained from HDL simulations and FPGA prototype have demonstrated the advantages of the proposed scheme.

Hardware Implementation of 32-Bit High-Speed Direct Digital Frequency Synthesizer

PubMed Central

Ibrahim, Salah Hasan; Ali, Sawal Hamid Md.; Islam, Md. Shabiul

2014-01-01

The design and implementation of a high-speed direct digital frequency synthesizer are presented. A modified Brent-Kung parallel adder is combined with pipelining technique to improve the speed of the system. A gated clock technique is proposed to reduce the number of registers in the phase accumulator design. The quarter wave symmetry technique is used to store only one quarter of the sine wave. The ROM lookup table (LUT) is partitioned into three 4-bit sub-ROMs based on angular decomposition technique and trigonometric identity. Exploiting the advantages of sine-cosine symmetrical attributes together with XOR logic gates, one sub-ROM block can be removed from the design. These techniques, compressed the ROM into 368 bits. The ROM compressed ratio is 534.2 : 1, with only two adders, two multipliers, and XOR-gates with high frequency resolution of 0.029 Hz. These techniques make the direct digital frequency synthesizer an attractive candidate for wireless communication applications. PMID:24991635

Scoping of Flood Hazard Mapping Needs for Belknap County, New Hampshire

DTIC Science & Technology

2006-01-01

DEM Digital Elevation Model DFIRM Digital Flood Insurance Rate Map DOQ Digital Orthophoto Quadrangle DOQQ Digital Ortho Quarter Quadrangle DTM...Agriculture Imag- ery Program (NAIP) color Digital Orthophoto Quadrangles (DOQs)). Remote sensing, base map information, GIS data (for example, contour data...found on USGS topographic maps. More recently developed data were derived from digital orthophotos providing improved base map accuracy. NH GRANIT is

Image correlation method for DNA sequence alignment.

PubMed

Curilem Saldías, Millaray; Villarroel Sassarini, Felipe; Muñoz Poblete, Carlos; Vargas Vásquez, Asticio; Maureira Butler, Iván

2012-01-01

The complexity of searches and the volume of genomic data make sequence alignment one of bioinformatics most active research areas. New alignment approaches have incorporated digital signal processing techniques. Among these, correlation methods are highly sensitive. This paper proposes a novel sequence alignment method based on 2-dimensional images, where each nucleic acid base is represented as a fixed gray intensity pixel. Query and known database sequences are coded to their pixel representation and sequence alignment is handled as object recognition in a scene problem. Query and database become object and scene, respectively. An image correlation process is carried out in order to search for the best match between them. Given that this procedure can be implemented in an optical correlator, the correlation could eventually be accomplished at light speed. This paper shows an initial research stage where results were "digitally" obtained by simulating an optical correlation of DNA sequences represented as images. A total of 303 queries (variable lengths from 50 to 4500 base pairs) and 100 scenes represented by 100 x 100 images each (in total, one million base pair database) were considered for the image correlation analysis. The results showed that correlations reached very high sensitivity (99.01%), specificity (98.99%) and outperformed BLAST when mutation numbers increased. However, digital correlation processes were hundred times slower than BLAST. We are currently starting an initiative to evaluate the correlation speed process of a real experimental optical correlator. By doing this, we expect to fully exploit optical correlation light properties. As the optical correlator works jointly with the computer, digital algorithms should also be optimized. The results presented in this paper are encouraging and support the study of image correlation methods on sequence alignment.

First high speed imaging of lightning from summer thunderstorms over India: Preliminary results based on amateur recording using a digital camera

NASA Astrophysics Data System (ADS)

Narayanan, V. L.

2017-12-01

For the first time, high speed imaging of lightning from few isolated tropical thunderstorms are observed from India. The recordings are made from Tirupati (13.6oN, 79.4oE, 180 m above mean sea level) during summer months with a digital camera capable of recording high speed videos up to 480 fps. At 480 fps, each individual video file is recorded for 30 s resulting in 14400 deinterlaced images per video file. An automatic processing algorithm is developed for quick identification and analysis of the lightning events which will be discussed in detail. Preliminary results indicating different types of phenomena associated with lightning like stepped leader, dart leader, luminous channels corresponding to continuing current and M components are discussed. While most of the examples show cloud to ground discharges, few interesting cases of intra-cloud, inter-cloud and cloud-air discharges will also be displayed. This indicates that though high speed cameras with few 1000 fps are preferred for a detailed study on lightning, moderate range CMOS sensor based digital cameras can provide important information as well. The lightning imaging activity presented herein is initiated as an amateur effort and currently plans are underway to propose a suite of supporting instruments to conduct coordinated campaigns. The images discussed here are acquired from normal residential area and indicate how frequent lightning strikes are in such tropical locations during thunderstorms, though no towering structures are nearby. It is expected that popularizing of such recordings made with affordable digital cameras will trigger more interest in lightning research and provide a possible data source from amateur observers paving the way for citizen science.

Influence of Waveform Characteristics on LiDAR Ranging Accuracy and Precision

PubMed Central

Yang, Bingwei; Xie, Xinhao; Li, Duan

2018-01-01

Time of flight (TOF) based light detection and ranging (LiDAR) is a technology for calculating distance between start/stop signals of time of flight. In lab-built LiDAR, two ranging systems for measuring flying time between start/stop signals include time-to-digital converter (TDC) that counts time between trigger signals and analog-to-digital converter (ADC) that processes the sampled start/stop pulses waveform for time estimation. We study the influence of waveform characteristics on range accuracy and precision of two kinds of ranging system. Comparing waveform based ranging (WR) with analog discrete return system based ranging (AR), a peak detection method (WR-PK) shows the best ranging performance because of less execution time, high ranging accuracy, and stable precision. Based on a novel statistic mathematical method maximal information coefficient (MIC), WR-PK precision has a high linear relationship with the received pulse width standard deviation. Thus keeping the received pulse width of measuring a constant distance as stable as possible can improve ranging precision. PMID:29642639

Librarian-Initiated Publications Discovery: How Do Digital Depository Librarians Discover and Select Web-Based Government Publications for State Digital Depositories?

ERIC Educational Resources Information Center

Lin, Chi-Shiou; Eschenfelder, Kristin R.

2010-01-01

This paper reports on a study of librarian initiated publications discovery (LIPD) in U.S. state digital depository programs using the OCLC Digital Archive to preserve web-based government publications for permanent public access. This paper describes a model of LIPD processes based on empirical investigations of four OCLC DA-based digital…

Field-Programmable Gate Array-based fluxgate magnetometer with digital integration

NASA Astrophysics Data System (ADS)

Butta, Mattia; Janosek, Michal; Ripka, Pavel

2010-05-01

In this paper, a digital magnetometer based on printed circuit board fluxgate is presented. The fluxgate is pulse excited and the signal is extracted by gate integration. We investigate the possibility to perform integration on very narrow gates (typically 500 ns) by using digital techniques. The magnetometer is based on field-programmable gate array (FPGA) card: we will show all the advantages and disadvantages, given by digitalization of fluxgate output voltage by means of analog-to-digital converter on FPGA card, as well as digitalization performed by external digitizer. Due to very narrow gate, it is shown that a magnetometer entirely based on a FPGA card is preferable, because it avoids noise due to trigger instability. Both open loop and feedback operative mode are described and achieved results are presented.

A copyright protection scheme for digital images based on shuffled singular value decomposition and visual cryptography.

PubMed

Devi, B Pushpa; Singh, Kh Manglem; Roy, Sudipta

2016-01-01

This paper proposes a new watermarking algorithm based on the shuffled singular value decomposition and the visual cryptography for copyright protection of digital images. It generates the ownership and identification shares of the image based on visual cryptography. It decomposes the image into low and high frequency sub-bands. The low frequency sub-band is further divided into blocks of same size after shuffling it and then the singular value decomposition is applied to each randomly selected block. Shares are generated by comparing one of the elements in the first column of the left orthogonal matrix with its corresponding element in the right orthogonal matrix of the singular value decomposition of the block of the low frequency sub-band. The experimental results show that the proposed scheme clearly verifies the copyright of the digital images, and is robust to withstand several image processing attacks. Comparison with the other related visual cryptography-based algorithms reveals that the proposed method gives better performance. The proposed method is especially resilient against the rotation attack.

The power of digital audio in interactive instruction: An unexploited medium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pratt, J.; Trainor, M.

1989-01-01

Widespread use of audio in computer-based training (CBT) occurred with the advent of the interactive videodisc technology. This paper discusses the alternative of digital audio, which, unlike videodisc audio, enables one to rapidly revise the audio used in the CBT and which may be used in nonvideo CBT applications as well. We also discuss techniques used in audio script writing, editing, and production. Results from evaluations indicate a high degree of user satisfaction. 4 refs.

Imaging RF Phased Array Receivers using Optically-Coherent Up-conversion for High Beam-Bandwidth Processing

DTIC Science & Technology

2017-03-01

It does so by using an optical lens to perform an inverse spatial Fourier Transform on the up-converted RF signals, thereby rendering a real-time... simultaneous beams or other engineered beam patterns. There are two general approaches to array-based beam forming: digital and analog. In digital beam...of significantly limiting the number of beams that can be formed simultaneously and narrowing the operational bandwidth. An alternate approach that

Direct-referencing Two-dimensional-array Digital Microfluidics Using Multi-layer Printed Circuit Board

PubMed Central

Gong, Jian; Kim, Chang-Jin “CJ”

2008-01-01

Digital (i.e. droplet-based) microfluidics, by the electrowetting-on-dielectric (EWOD) mechanism, has shown great potential for a wide range of applications, such as lab-on-a-chip. While most reported EWOD chips use a series of electrode pads essentially in one-dimensional line pattern designed for specific tasks, the desired universal chips allowing user-reconfigurable paths would require the electrode pads in two-dimensional pattern. However, to electrically access the electrode pads independently, conductive lines need to be fabricated underneath the pads in multiple layers, raising a cost issue especially for disposable chip applications. In this article, we report the building of digital microfluidic plates based on a printed-circuit-board (PCB), in which multilayer electrical access lines were created inexpensively using mature PCB technology. However, due to its surface topography and roughness and resulting high resistance against droplet movement, as-fabricated PCB surfaces require unacceptably high (~500 V) voltages unless coated with or immersed in oil. Our goal is EWOD operations of aqueous droplets not only on oil-covered but also on dry surfaces. To meet varying levels of performances, three types of gradually complex post-PCB microfabrication processes are developed and evaluated. By introducing land-grid-array (LGA) sockets in the packaging, a scalable digital microfluidics system with reconfigurable and low-cost chip is also demonstrated. PMID:19234613

Digital test signal generation: An accurate SNR calibration approach for the DSN

NASA Technical Reports Server (NTRS)

Gutierrez-Luaces, Benito O.

1993-01-01

In support of the on-going automation of the Deep Space Network (DSN) a new method of generating analog test signals with accurate signal-to-noise ratio (SNR) is described. High accuracy is obtained by simultaneous generation of digital noise and signal spectra at the desired bandwidth (base-band or bandpass). The digital synthesis provides a test signal embedded in noise with the statistical properties of a stationary random process. Accuracy is dependent on test integration time and limited only by the system quantization noise (0.02 dB). The monitor and control as well as signal-processing programs reside in a personal computer (PC). Commands are transmitted to properly configure the specially designed high-speed digital hardware. The prototype can generate either two data channels modulated or not on a subcarrier, or one QPSK channel, or a residual carrier with one biphase data channel. The analog spectrum generated is on the DC to 10 MHz frequency range. These spectra may be up-converted to any desired frequency without loss on the characteristics of the SNR provided. Test results are presented.

Controlled power delivery for super-resolution imaging of biological samples using digital micromirror device

NASA Astrophysics Data System (ADS)

Valiya Peedikakkal, Liyana; Cadby, Ashley

2017-02-01

Localization based super resolution images of a biological sample is generally achieved by using high power laser illumination with long exposure time which unfortunately increases photo-toxicity of a sample, making super resolution microscopy, in general, incompatible with live cell imaging. Furthermore, the limitation of photobleaching reduces the ability to acquire time lapse images of live biological cells using fluorescence microscopy. Digital Light Processing (DLP) technology can deliver light at grey scale levels by flickering digital micromirrors at around 290 Hz enabling highly controlled power delivery to samples. In this work, Digital Micromirror Device (DMD) is implemented in an inverse Schiefspiegler telescope setup to control the power and pattern of illumination for super resolution microscopy. We can achieve spatial and temporal patterning of illumination by controlling the DMD pixel by pixel. The DMD allows us to control the power and spatial extent of the laser illumination. We have used this to show that we can reduce the power delivered to the sample to allow for longer time imaging in one area while achieving sub-diffraction STORM imaging in another using higher power densities.

Method and apparatus for data sampling

DOEpatents

Odell, D.M.C.

1994-04-19

A method and apparatus for sampling radiation detector outputs and determining event data from the collected samples is described. The method uses high speed sampling of the detector output, the conversion of the samples to digital values, and the discrimination of the digital values so that digital values representing detected events are determined. The high speed sampling and digital conversion is performed by an A/D sampler that samples the detector output at a rate high enough to produce numerous digital samples for each detected event. The digital discrimination identifies those digital samples that are not representative of detected events. The sampling and discrimination also provides for temporary or permanent storage, either serially or in parallel, to a digital storage medium. 6 figures.

The Influence of Working Memory Load on Expectancy-Based Strategic Processes in the Stroop-Priming Task.

PubMed

Ortells, Juan J; Álvarez, Dolores; Noguera, Carmen; Carmona, Encarna; de Fockert, Jan W

2017-01-01

The present study investigated whether a differential availability of cognitive control resources as a result of varying working memory (WM) load could affect the capacity for expectancy-based strategic actions. Participants performed a Stroop-priming task in which a prime word (GREEN or RED) was followed by a colored target (red vs. green) that participants had to identify. The prime was incongruent or congruent with the target color on 80 and 20% of the trials, respectively, and participants were informed about the differential proportion of congruent vs. incongruent trials. This task was interleaved with a WM task, such that the prime word was preceded by a sequence of either a same digit repeated five times (low load) or five different random digits (high load), which should be retained by participants. After two, three, or four Stroop trials, they had to decide whether or not a probe digit was a part of the memory set. The key finding was a significant interaction between prime-target congruency and WM load: Whereas a strategy-dependent (reversed Stroop) effect was found under low WM load, a standard Stroop interference effect was observed under high WM load. These findings demonstrate that the availability of WM is crucial for implementing expectancy-based strategic actions.

Image compression system and method having optimized quantization tables

NASA Technical Reports Server (NTRS)

Ratnakar, Viresh (Inventor); Livny, Miron (Inventor)

1998-01-01

A digital image compression preprocessor for use in a discrete cosine transform-based digital image compression device is provided. The preprocessor includes a gathering mechanism for determining discrete cosine transform statistics from input digital image data. A computing mechanism is operatively coupled to the gathering mechanism to calculate a image distortion array and a rate of image compression array based upon the discrete cosine transform statistics for each possible quantization value. A dynamic programming mechanism is operatively coupled to the computing mechanism to optimize the rate of image compression array against the image distortion array such that a rate-distortion-optimal quantization table is derived. In addition, a discrete cosine transform-based digital image compression device and a discrete cosine transform-based digital image compression and decompression system are provided. Also, a method for generating a rate-distortion-optimal quantization table, using discrete cosine transform-based digital image compression, and operating a discrete cosine transform-based digital image compression and decompression system are provided.

Synthesis of a fully-integrated digital signal source for communications from chaotic dynamics-based oscillations

NASA Astrophysics Data System (ADS)

Glenn, Chance Michael, Sr.

This work is the conceptualization, derivation, analysis, and fabrication of a fully practical digital signal source designed from a chaotic oscillator. In it we show how a simple electronic circuit based upon the Colpitts oscillator, can be made to produce highly complex signals capable of carrying digital information. We show a direct relationship between the continuous-time chaotic oscillations produced by the circuit and the logistic map, which is discrete-time, one-dimensional map that is a fundamental paradigm for the study of chaotic systems. We demonstrate the direct encoding of binary information into the oscillations of the chaotic circuit. We demonstrate a new concept in power amplification, called syncrodyne amplification , which uses fundamental properties of chaotic oscillators to provide high-efficiency, high gain amplification of standard communication waveforms as well as typical chaotic oscillations. We show modeling results of this system providing nearly 60-dB power gain and 80% PAE for communications waveforms conforming to GMSK modulation. Finally we show results from a fabricated syncrodyne amplifier circuit operating at 2 MHz, providing over 40-dB power gain and 72% PAE, and propose design criteria for an 824--850 MHz circuit utilizing heterojunction bipolar transistors (HBTs), providing the basis for microwave frequency realization.

Recoded and nonrecoded trinary signed-digit adders and multipliers with redundant-bit representations

NASA Astrophysics Data System (ADS)

Cherri, Abdallah K.; Alam, Mohammed S.

1998-07-01

Highly-efficient two-step recoded and one-step nonrecoded trinary signed-digit (TSD) carry-free adders subtracters are presented on the basis of redundant-bit representation for the operands digits. It has been shown that only 24 (30) minterms are needed to implement the two-step recoded (the one-step nonrecoded) TSD addition for any operand length. Optical implementation of the proposed arithmetic can be carried out by use of correlation- or matrix-multiplication-based schemes, saving 50% of the system memory. Furthermore, we present four different multiplication designs based on our proposed recoded and nonrecoded TSD adders. Our multiplication designs require a small number of reduced minterms to generate the multiplication partial products. Finally, a recently proposed pipelined iterative-tree algorithm can be used in the TSD adders multipliers; consequently, efficient use of all available adders can be made.

Recoded and nonrecoded trinary signed-digit adders and multipliers with redundant-bit representations.

PubMed

Cherri, A K; Alam, M S

1998-07-10

Highly-efficient two-step recoded and one-step nonrecoded trinary signed-digit (TSD) carry-free adders-subtracters are presented on the basis of redundant-bit representation for the operands' digits. It has been shown that only 24 (30) minterms are needed to implement the two-step recoded (the one-step nonrecoded) TSD addition for any operand length. Optical implementation of the proposed arithmetic can be carried out by use of correlation- or matrix-multiplication-based schemes, saving 50% of the system memory. Furthermore, we present four different multiplication designs based on our proposed recoded and nonrecoded TSD adders. Our multiplication designs require a small number of reduced minterms to generate the multiplication partial products. Finally, a recently proposed pipelined iterative-tree algorithm can be used in the TSD adders-multipliers; consequently, efficient use of all available adders can be made.

Robust Audio Watermarking Scheme Based on Deterministic Plus Stochastic Model

NASA Astrophysics Data System (ADS)

Dhar, Pranab Kumar; Kim, Cheol Hong; Kim, Jong-Myon

Digital watermarking has been widely used for protecting digital contents from unauthorized duplication. This paper proposes a new watermarking scheme based on spectral modeling synthesis (SMS) for copyright protection of digital contents. SMS defines a sound as a combination of deterministic events plus a stochastic component that makes it possible for a synthesized sound to attain all of the perceptual characteristics of the original sound. In our proposed scheme, watermarks are embedded into the highest prominent peak of the magnitude spectrum of each non-overlapping frame in peak trajectories. Simulation results indicate that the proposed watermarking scheme is highly robust against various kinds of attacks such as noise addition, cropping, re-sampling, re-quantization, and MP3 compression and achieves similarity values ranging from 17 to 22. In addition, our proposed scheme achieves signal-to-noise ratio (SNR) values ranging from 29 dB to 30 dB.

Reconfigurable fuzzy cell

NASA Technical Reports Server (NTRS)

Salazar, George A. (Inventor)

1993-01-01

This invention relates to a reconfigurable fuzzy cell comprising a digital control programmable gain operation amplifier, an analog-to-digital converter, an electrically erasable PROM, and 8-bit counter and comparator, and supporting logic configured to achieve in real-time fuzzy systems high throughput, grade-of-membership or membership-value conversion of multi-input sensor data. The invention provides a flexible multiplexing-capable configuration, implemented entirely in hardware, for effectuating S-, Z-, and PI-membership functions or combinations thereof, based upon fuzzy logic level-set theory. A membership value table storing 'knowledge data' for each of S-, Z-, and PI-functions is contained within a nonvolatile memory for storing bits of membership and parametric information in a plurality of address spaces. Based upon parametric and control signals, analog sensor data is digitized and converted into grade-of-membership data. In situ learn and recognition modes of operation are also provided.

Use of contextual inquiry to understand anatomic pathology workflow: Implications for digital pathology adoption

PubMed Central

Ho, Jonhan; Aridor, Orly; Parwani, Anil V.

2012-01-01

Background: For decades anatomic pathology (AP) workflow have been a highly manual process based on the use of an optical microscope and glass slides. Recent innovations in scanning and digitizing of entire glass slides are accelerating a move toward widespread adoption and implementation of a workflow based on digital slides and their supporting information management software. To support the design of digital pathology systems and ensure their adoption into pathology practice, the needs of the main users within the AP workflow, the pathologists, should be identified. Contextual inquiry is a qualitative, user-centered, social method designed to identify and understand users’ needs and is utilized for collecting, interpreting, and aggregating in-detail aspects of work. Objective: Contextual inquiry was utilized to document current AP workflow, identify processes that may benefit from the introduction of digital pathology systems, and establish design requirements for digital pathology systems that will meet pathologists’ needs. Materials and Methods: Pathologists were observed and interviewed at a large academic medical center according to contextual inquiry guidelines established by Holtzblatt et al. 1998. Notes representing user-provided data were documented during observation sessions. An affinity diagram, a hierarchal organization of the notes based on common themes in the data, was created. Five graphical models were developed to help visualize the data including sequence, flow, artifact, physical, and cultural models. Results: A total of six pathologists were observed by a team of two researchers. A total of 254 affinity notes were documented and organized using a system based on topical hierarchy, including 75 third-level, 24 second-level, and five main-level categories, including technology, communication, synthesis/preparation, organization, and workflow. Current AP workflow was labor intensive and lacked scalability. A large number of processes that may possibly improve following the introduction of digital pathology systems were identified. These work processes included case management, case examination and review, and final case reporting. Furthermore, a digital slide system should integrate with the anatomic pathologic laboratory information system. Conclusions: To our knowledge, this is the first study that utilized the contextual inquiry method to document AP workflow. Findings were used to establish key requirements for the design of digital pathology systems. PMID:23243553

Digital Game Playing and Direct and Indirect Aggression in Early Adolescence: The Roles of Age, Social Intelligence, and Parent-Child Communication.

PubMed

Wallenius, Marjut; Punamäki, Raija-Leena; Rimpelä, Arja

2007-04-01

The roles of age, social intelligence and parent-child communication in moderating the association between digital game playing and direct and indirect aggression were examined in 478 Finnish 10- and 13-year-old schoolchildren based on self-reports. The results confirmed that digital game violence was directly associated with direct aggression, especially at age 10, but only among boys. The moderating role of social intelligence was substantiated among older boys: game violence was associated with indirect aggression among those with high level of social intelligence. Further, as hypothesized, digital game playing was associated with direct aggression especially when parent-child communication was poor, but only among boys. Our findings emphasize the importance of individual and situational factors as moderators of the link between game violence and aggression.

Digital Morphometrics: A New Upper Airway Phenotyping Paradigm in OSA.

PubMed

Schwab, Richard J; Leinwand, Sarah E; Bearn, Cary B; Maislin, Greg; Rao, Ramya Bhat; Nagaraja, Adithya; Wang, Stephen; Keenan, Brendan T

2017-08-01

OSA is associated with changes in pharyngeal anatomy. The goal of this study was to objectively and reproducibly quantify pharyngeal anatomy by using digital morphometrics based on a laser ruler and to assess differences between subjects with OSA and control subjects and associations with the apnea-hypopnea index (AHI). To the best of our knowledge, this study is the first to use digital morphometrics to quantify intraoral risk factors for OSA. Digital photographs were obtained by using an intraoral laser ruler and digital camera in 318 control subjects (mean AHI, 4.2 events/hour) and 542 subjects with OSA (mean AHI, 39.2 events/hour). The digital morphometric paradigm was validated and reproducible over time and camera distances. A larger modified Mallampati score and having a nonvisible airway were associated with a higher AHI, both unadjusted (P < .001) and controlling for age, sex, race, and BMI (P = .015 and P = .018, respectively). Measures of tongue size were larger in subjects with OSA vs control subjects in unadjusted models and controlling for age, sex, and race but nonsignificant controlling for BMI; similar results were observed with AHI severity. Multivariate regression suggests photography-based variables capture independent associations with OSA. Measures of tongue size, airway visibility, and Mallampati scores were associated with increased OSA risk and severity. This study shows that digital morphometrics is an accurate, high-throughput, and noninvasive technique to identify anatomic OSA risk factors. Morphometrics may also provide a more reproducible and standardized measurement of the Mallampati score. Digital morphometrics represent an efficient and cost-effective method of examining intraoral crowding and tongue size when examining large populations, genetics, or screening for OSA. Copyright © 2017 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

A digital optical phase-locked loop for diode lasers based on field programmable gate array.

PubMed

Xu, Zhouxiang; Zhang, Xian; Huang, Kaikai; Lu, Xuanhui

2012-09-01

We have designed and implemented a highly digital optical phase-locked loop (OPLL) for diode lasers in atom interferometry. The three parts of controlling circuit in this OPLL, including phase and frequency detector (PFD), loop filter and proportional integral derivative (PID) controller, are implemented in a single field programmable gate array chip. A structure type compatible with the model MAX9382∕MCH12140 is chosen for PFD and pipeline and parallelism technology have been adapted in PID controller. Especially, high speed clock and twisted ring counter have been integrated in the most crucial part, the loop filter. This OPLL has the narrow beat note line width below 1 Hz, residual mean-square phase error of 0.14 rad(2) and transition time of 100 μs under 10 MHz frequency step. A main innovation of this design is the completely digitalization of the whole controlling circuit in OPLL for diode lasers.

A digital optical phase-locked loop for diode lasers based on field programmable gate array

NASA Astrophysics Data System (ADS)

Xu, Zhouxiang; Zhang, Xian; Huang, Kaikai; Lu, Xuanhui

2012-09-01

We have designed and implemented a highly digital optical phase-locked loop (OPLL) for diode lasers in atom interferometry. The three parts of controlling circuit in this OPLL, including phase and frequency detector (PFD), loop filter and proportional integral derivative (PID) controller, are implemented in a single field programmable gate array chip. A structure type compatible with the model MAX9382/MCH12140 is chosen for PFD and pipeline and parallelism technology have been adapted in PID controller. Especially, high speed clock and twisted ring counter have been integrated in the most crucial part, the loop filter. This OPLL has the narrow beat note line width below 1 Hz, residual mean-square phase error of 0.14 rad2 and transition time of 100 μs under 10 MHz frequency step. A main innovation of this design is the completely digitalization of the whole controlling circuit in OPLL for diode lasers.

A high-resolution time-to-digital converter using a three-level resolution

NASA Astrophysics Data System (ADS)

Dehghani, Asma; Saneei, Mohsen; Mahani, Ali

2016-08-01

In this article, a three-level resolution Vernier delay line time-to-digital converter (TDC) was proposed. The proposed TDC core was based on the pseudo-differential digital architecture that made it insensitive to nMOS and pMOS transistor mismatches. It also employed a Vernier delay line (VDL) in conjunction with an asynchronous read-out circuitry. The time interval resolution was equal to the difference of delay between buffers of upper and lower chains. Then, via the extra chain included in the lower delay line, resolution was controlled and power consumption was reduced. This method led to high resolution and low power consumption. The measurement results of TDC showed a resolution of 4.5 ps, 12-bit output dynamic range, and integral nonlinearity of 1.5 least significant bits. This TDC achieved the consumption of 68.43 µW from 1.1-V supply.

Kilohertz binary phase modulator for pulsed laser sources using a digital micromirror device.

PubMed

Hoffmann, Maximilian; Papadopoulos, Ioannis N; Judkewitz, Benjamin

2018-01-01

The controlled modulation of an optical wavefront is required for aberration correction, digital phase conjugation, or patterned photostimulation. For most of these applications, it is desirable to control the wavefront modulation at the highest rates possible. The digital micromirror device (DMD) presents a cost-effective solution to achieve high-speed modulation and often exceeds the speed of the more conventional liquid crystal spatial light modulator but is inherently an amplitude modulator. Furthermore, spatial dispersion caused by DMD diffraction complicates its use with pulsed laser sources, such as those used in nonlinear microscopy. Here we introduce a DMD-based optical design that overcomes these limitations and achieves dispersion-free high-speed binary phase modulation. We show that this phase modulation can be used to switch through binary phase patterns at the rate of 20 kHz in two-photon excitation fluorescence applications.

Kilohertz binary phase modulator for pulsed laser sources using a digital micromirror device

NASA Astrophysics Data System (ADS)

Hoffmann, Maximilian; Papadopoulos, Ioannis N.; Judkewitz, Benjamin

2018-01-01

The controlled modulation of an optical wavefront is required for aberration correction, digital phase conjugation or patterned photostimulation. For most of these applications it is desirable to control the wavefront modulation at the highest rates possible. The digital micromirror device (DMD) presents a cost-effective solution to achieve high-speed modulation and often exceeds the speed of the more conventional liquid crystal spatial light modulator, but is inherently an amplitude modulator. Furthermore, spatial dispersion caused by DMD diffraction complicates its use with pulsed laser sources, such as those used in nonlinear microscopy. Here we introduce a DMD-based optical design that overcomes these limitations and achieves dispersion-free high-speed binary phase modulation. We show that this phase modulation can be used to switch through binary phase patterns at the rate of 20 kHz in two-photon excitation fluorescence applications.

The effect of prior education on students' competency in digital logic: the case of ultraorthodox Jewish students

NASA Astrophysics Data System (ADS)

Ben-David Kolikant, Yifat; Genut, Sara

2017-10-01

In line with the growing interest in extending the diversity of CS students, we examined the performance of a unique group of students studying an introductory course in Digital logic: ultraorthodox Jewish men, whose previous education was based mostly on studying Talmud and who lacked a conventional high-school education. We used questions from the Digital Logic Concept Inventory . We compared the results to those of religious Jewish men with a conventional high-school education, and to the results reported in the literature. The ultraorthodox group performed better than the other groups in tasks that concerned number representation. No other statistically significant differences were found. Talk-aloud protocols revealed that the ultraorthodox students utilized a viable conceptual understanding in their performance. We can conclude that students' unique, alternative prior education should not be merely viewed as an obstacle to their academic studies, but also as a potential source for strengths.

Lunar mineral feedstocks from rocks and soils: X-ray digital imaging in resource evaluation

NASA Technical Reports Server (NTRS)

Chambers, John G.; Patchen, Allan; Taylor, Lawrence A.; Higgins, Stefan J.; Mckay, David S.

1994-01-01

The rocks and soils of the Moon provide raw materials essential to the successful establishment of a lunar base. Efficient exploitation of these resources requires accurate characterization of mineral abundances, sizes/shapes, and association of 'ore' and 'gangue' phases, as well as the technology to generate high-yield/high-grade feedstocks. Only recently have x-ray mapping and digital imaging techniques been applied to lunar resource evaluation. The topics covered include inherent differences between lunar basalts and soils and quantitative comparison of rock-derived and soil-derived ilmenite concentrates. It is concluded that x-ray digital-imaging characterization of lunar raw materials provides a quantitative comparison that is unattainable by traditional petrographic techniques. These data are necessary for accurately determining mineral distributions of soil and crushed rock material. Application of these techniques will provide an important link to choosing the best raw material for mineral beneficiation.

Interacting with Visual Poems through AR-Based Digital Artwork

ERIC Educational Resources Information Center

Lin, Hao-Chiang Koong; Hsieh, Min-Chai; Liu, Eric Zhi-Feng; Chuang, Tsung-Yen

2012-01-01

In this study, an AR-based digital artwork called "Mind Log" was designed and evaluated. The augmented reality technique was employed to create digital artwork that would present interactive poems. A digital poem was generated via the interplay between a video film and a text-based poem. This artwork was created following a rigorous design flow,…

Compton suppression and event triggering in a commercial data acquisition system

NASA Astrophysics Data System (ADS)

Tabor, Samuel; Caussyn, D. D.; Tripathi, Vandana; Vonmoss, J.; Liddick, S. N.

2012-10-01

A number of groups are starting to use flash digitizer systems to directly convert the preamplifier signals of high-resolution Ge detectors to a stream of digital data. Some digitizers are also equipped with software constant fraction discriminator algorithms capable of operating on the resulting digital data stream to provide timing information. Because of the dropping cost per channel of these systems, it should now be possible to also connect outputs of the Bismuth Germanate (BGO) scintillators used for Compton suppression to other digitizer inputs so that BGO logic signals can also be available in the same system. This provides the possibility to perform all the Compton suppression and multiplicity trigger logic within the digital system, thus eliminating the need for separate timing filter amplifiers (TFA), constant fraction discriminators (CFD), logic units, and lots of cables. This talk will describe the performance of such a system based on Pixie16 modules from XIA LLC with custom field programmable gate array (FPGA) programming for an array of Compton suppressed single Ge crystal and 4-crystal ``Clover'' detector array along with optional particle detectors. Initial tests of the system have produced results comparable with the current traditional system of individual electronics and peak sensing analog to digital converters. The advantages of the all digital system will be discussed.

Fully digital data processing during cardiovascular implantable electronic device follow-up in a high-volume tertiary center.

PubMed

Staudacher, Ingo; Nalpathamkalam, Asha Roy; Uhlmann, Lorenz; Illg, Claudius; Seehausen, Sebastian; Akhavanpoor, Mohammadreza; Buchauer, Anke; Geis, Nicolas; Lugenbiel, Patrick; Schweizer, Patrick A; Xynogalos, Panagiotis; Zylla, Maura M; Scholz, Eberhard; Zitron, Edgar; Katus, Hugo A; Thomas, Dierk

2017-10-11

Increasing numbers of patients with cardiovascular implantable electronic devices (CIEDs) and limited follow-up capacities highlight unmet challenges in clinical electrophysiology. Integrated software (MediConnect ® ) enabling fully digital processing of device interrogation data has been commercially developed to facilitate follow-up visits. We sought to assess feasibility of fully digital data processing (FDDP) during ambulatory device follow-up in a high-volume tertiary hospital to provide guidance for future users of FDDP software. A total of 391 patients (mean age, 70 years) presenting to the outpatient department for routine device follow-up were analyzed (pacemaker, 44%; implantable cardioverter defibrillator, 39%; cardiac resynchronization therapy device, 16%). Quality of data transfer and follow-up duration were compared between digital (n = 265) and manual processing of device data (n = 126). Digital data import was successful, complete and correct in 82% of cases when early software versions were used. When using the most recent software version the rate of successful digital data import increased to 100%. Software-based import of interrogation data was complete and without failure in 97% of cases. The mean duration of a follow-up visit did not differ between the two groups (digital 18.7 min vs. manual data transfer 18.2 min). FDDP software was successfully implemented into the ambulatory follow-up of patients with implanted pacemakers and defibrillators. Digital data import into electronic patient management software was feasible and supported the physician's workflow. The total duration of follow-up visits comprising technical device interrogation and clinical actions was not affected in the present tertiary center outpatient cohort.

A bunch to bucket phase detector for the RHIC LLRF upgrade platform

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, K.S.; Harvey, M.; Hayes, T.

2011-03-28

As part of the overall development effort for the RHIC LLRF Upgrade Platform [1,2,3], a generic four channel 16 bit Analog-to-Digital Converter (ADC) daughter module was developed to provide high speed, wide dynamic range digitizing and processing of signals from DC to several hundred megahertz. The first operational use of this card was to implement the bunch to bucket phase detector for the RHIC LLRF beam control feedback loops. This paper will describe the design and performance features of this daughter module as a bunch to bucket phase detector, and also provide an overview of its place within the overallmore » LLRF platform architecture as a high performance digitizer and signal processing module suitable to a variety of applications. In modern digital control and signal processing systems, ADCs provide the interface between the analog and digital signal domains. Once digitized, signals are then typically processed using algorithms implemented in field programmable gate array (FPGA) logic, general purpose processors (GPPs), digital signal processors (DSPs) or a combination of these. For the recently developed and commissioned RHIC LLRF Upgrade Platform, we've developed a four channel ADC daughter module based on the Linear Technology LTC2209 16 bit, 160 MSPS ADC and the Xilinx V5FX70T FPGA. The module is designed to be relatively generic in application, and with minimal analog filtering on board, is capable of processing signals from DC to 500 MHz or more. The module's first application was to implement the bunch to bucket phase detector (BTB-PD) for the RHIC LLRF system. The same module also provides DC digitizing of analog processed BPM signals used by the LLRF system for radial feedback.« less

A model for a PC-based, universal-format, multimedia digitization system: moving beyond the scanner.

PubMed

McEachen, James C; Cusack, Thomas J; McEachen, John C

2003-08-01

Digitizing images for use in case presentations based on hardcopy films, slides, photographs, negatives, books, and videos can present a challenging task. Scanners and digital cameras have become standard tools of the trade. Unfortunately, use of these devices to digitize multiple images in many different media formats can be a time-consuming and in some cases unachievable process. The authors' goal was to create a PC-based solution for digitizing multiple media formats in a timely fashion while maintaining adequate image presentation quality. The authors' PC-based solution makes use of off-the-shelf hardware applications to include a digital document camera (DDC), VHS video player, and video-editing kit. With the assistance of five staff radiologists, the authors examined the quality of multiple image types digitized with this equipment. The authors also quantified the speed of digitization of various types of media using the DDC and video-editing kit. With regard to image quality, the five staff radiologists rated the digitized angiography, CT, and MR images as adequate to excellent for use in teaching files and case presentations. With regard to digitized plain films, the average rating was adequate. As for performance, the authors recognized a 68% improvement in the time required to digitize hardcopy films using the DDC instead of a professional quality scanner. The PC-based solution provides a means for digitizing multiple images from many different types of media in a timely fashion while maintaining adequate image presentation quality.

The Process, Dialogues, and Attitudes of Vocational Engineering High School Students in a Web Problem-Based Learning (WPBL) System

ERIC Educational Resources Information Center

Tseng, Kuo-Hung; Chang, Chi-Cheng; Lou, Shi-Jer

2012-01-01

This study aims to explore how high school students collaboratively solve problems in a web problem-based learning (WPBL) system in an 8-week digital logic course using discourse analysis. Employing in-depth interviews, this study also investigated the students' attitudes toward the WPBL system. The number of teaching assistants' responses had a…

Design exploration and verification platform, based on high-level modeling and FPGA prototyping, for fast and flexible digital communication in physics experiments

NASA Astrophysics Data System (ADS)

Magazzù, G.; Borgese, G.; Costantino, N.; Fanucci, L.; Incandela, J.; Saponara, S.

2013-02-01

In many research fields as high energy physics (HEP), astrophysics, nuclear medicine or space engineering with harsh operating conditions, the use of fast and flexible digital communication protocols is becoming more and more important. The possibility to have a smart and tested top-down design flow for the design of a new protocol for control/readout of front-end electronics is very useful. To this aim, and to reduce development time, costs and risks, this paper describes an innovative design/verification flow applied as example case study to a new communication protocol called FF-LYNX. After the description of the main FF-LYNX features, the paper presents: the definition of a parametric SystemC-based Integrated Simulation Environment (ISE) for high-level protocol definition and validation; the set up of figure of merits to drive the design space exploration; the use of ISE for early analysis of the achievable performances when adopting the new communication protocol and its interfaces for a new (or upgraded) physics experiment; the design of VHDL IP cores for the TX and RX protocol interfaces; their implementation on a FPGA-based emulator for functional verification and finally the modification of the FPGA-based emulator for testing the ASIC chipset which implements the rad-tolerant protocol interfaces. For every step, significant results will be shown to underline the usefulness of this design and verification approach that can be applied to any new digital protocol development for smart detectors in physics experiments.

A standardized way to select, evaluate, and test an analog-to-digital converter for ultrawide bandwidth radiofrequency signals based on user's needs, ideal, published,and actual specifications

NASA Astrophysics Data System (ADS)

Chang, Daniel Y.; Rowe, Neil C.

2012-06-01

The most important adverse impact on the Electronic Warfare (EW) simulation is that the number of signal sources that can be tested simultaneously is relatively small. When the number of signal sources increases, the analog hardware, complexity and costs grow by the order of N2, since the number of connections among N components is O(N*N) and the signal communication is bi-directional. To solve this problem, digitization of the signal is suggested. In digitizing a radiofrequency signal, an Analog-to-Digital Converter (ADC) is widely used. Most research studies on ADCs are conducted from designer/test engineers' perspective. Some research studies are conducted from market's perspective. This paper presents a generic way to select, evaluate and test ultra high bandwidth COTS ADCs and generate requirements for digitizing continuous time signals from the perspective of user's needs. Based on user's needs, as well as vendor's published, ideal and actual specifications, a decision can be made in selecting a proper ADC for an application. To support our arguments and illustrate the methodology, we evaluate a Tektronix TADC-1000, an 8-bit and 12 gigasamples per second ADC. This project is funded by JEWEL lab, NAWCWD at Point Mugu, CA.

Design of Efficient Mirror Adder in Quantum- Dot Cellular Automata

NASA Astrophysics Data System (ADS)

Mishra, Prashant Kumar; Chattopadhyay, Manju K.

2018-03-01

Lower power consumption is an essential demand for portable multimedia system using digital signal processing algorithms and architectures. Quantum dot cellular automata (QCA) is a rising nano technology for the development of high performance ultra-dense low power digital circuits. QCA based several efficient binary and decimal arithmetic circuits are implemented, however important improvements are still possible. This paper demonstrate Mirror Adder circuit design in QCA. We present comparative study of mirror adder cells designed using conventional CMOS technique and mirror adder cells designed using quantum-dot cellular automata. QCA based mirror adders are better in terms of area by order of three.

An open-source computational and data resource to analyze digital maps of immunopeptidomes

DOE PAGES

Caron, Etienne; Espona, Lucia; Kowalewski, Daniel J.; ...

2015-07-08

We present a novel mass spectrometry-based high-throughput workflow and an open-source computational and data resource to reproducibly identify and quantify HLA-associated peptides. Collectively, the resources support the generation of HLA allele-specific peptide assay libraries consisting of consensus fragment ion spectra, and the analysis of quantitative digital maps of HLA peptidomes generated from a range of biological sources by SWATH mass spectrometry (MS). This study represents the first community-based effort to develop a robust platform for the reproducible and quantitative measurement of the entire repertoire of peptides presented by HLA molecules, an essential step towards the design of efficient immunotherapies.

High-accuracy resolver-to-digital conversion via phase locked loop based on PID controller

NASA Astrophysics Data System (ADS)

Li, Yaoling; Wu, Zhong

2018-03-01

The problem of resolver-to-digital conversion (RDC) is transformed into the problem of angle tracking control, and a phase locked loop (PLL) method based on PID controller is proposed in this paper. This controller comprises a typical PI controller plus an incomplete differential which can avoid the amplification of higher-frequency noise components by filtering the phase detection error with a low-pass filter. Compared with conventional ones, the proposed PLL method makes the converter a system of type III and thus the conversion accuracy can be improved. Experimental results demonstrate the effectiveness of the proposed method.

Digital Correlation Microwave Polarimetry: Analysis and Demonstration

NASA Technical Reports Server (NTRS)

Piepmeier, J. R.; Gasiewski, A. J.; Krebs, Carolyn A. (Technical Monitor)

2000-01-01

The design, analysis, and demonstration of a digital-correlation microwave polarimeter for use in earth remote sensing is presented. We begin with an analysis of three-level digital correlation and develop the correlator transfer function and radiometric sensitivity. A fifth-order polynomial regression is derived for inverting the digital correlation coefficient into the analog statistic. In addition, the effects of quantizer threshold asymmetry and hysteresis are discussed. A two-look unpolarized calibration scheme is developed for identifying correlation offsets. The developed theory and calibration method are verified using a 10.7 GHz and a 37.0 GHz polarimeter. The polarimeters are based upon 1-GS/s three-level digital correlators and measure the first three Stokes parameters. Through experiment, the radiometric sensitivity is shown to approach the theoretical as derived earlier in the paper and the two-look unpolarized calibration method is successfully compared with results using a polarimetric scheme. Finally, sample data from an aircraft experiment demonstrates that the polarimeter is highly-useful for ocean wind-vector measurement.

Parallel digital modem using multirate digital filter banks

NASA Technical Reports Server (NTRS)

Sadr, Ramin; Vaidyanathan, P. P.; Raphaeli, Dan; Hinedi, Sami

1994-01-01

A new class of architectures for an all-digital modem is presented in this report. This architecture, referred to as the parallel receiver (PRX), is based on employing multirate digital filter banks (DFB's) to demodulate, track, and detect the received symbol stream. The resulting architecture is derived, and specifications are outlined for designing the DFB for the PRX. The key feature of this approach is a lower processing rate then either the Nyquist rate or the symbol rate, without any degradation in the symbol error rate. Due to the freedom in choosing the processing rate, the designer is able to arbitrarily select and use digital components, independent of the speed of the integrated circuit technology. PRX architecture is particularly suited for high data rate applications, and due to the modular structure of the parallel signal path, expansion to even higher data rates is accommodated with each. Applications of the PRX would include gigabit satellite channels, multiple spacecraft, optical links, interactive cable-TV, telemedicine, code division multiple access (CDMA) communications, and others.

Three-dimensional image signals: processing methods

NASA Astrophysics Data System (ADS)

Schiopu, Paul; Manea, Adrian; Craciun, Anca-Ileana; Craciun, Alexandru

2010-11-01

Over the years extensive studies have been carried out to apply coherent optics methods in real-time processing, communications and transmission image. This is especially true when a large amount of information needs to be processed, e.g., in high-resolution imaging. The recent progress in data-processing networks and communication systems has considerably increased the capacity of information exchange. We describe the results of literature investigation research of processing methods for the signals of the three-dimensional images. All commercially available 3D technologies today are based on stereoscopic viewing. 3D technology was once the exclusive domain of skilled computer-graphics developers with high-end machines and software. The images capture from the advanced 3D digital camera can be displayed onto screen of the 3D digital viewer with/ without special glasses. For this is needed considerable processing power and memory to create and render the complex mix of colors, textures, and virtual lighting and perspective necessary to make figures appear three-dimensional. Also, using a standard digital camera and a technique called phase-shift interferometry we can capture "digital holograms." These are holograms that can be stored on computer and transmitted over conventional networks. We present some research methods to process "digital holograms" for the Internet transmission and results.

An Interactive Program on Digitizing Historical Seismograms

NASA Astrophysics Data System (ADS)

Xu, Y.; Xu, T.

2013-12-01

Retrieving information from historical seismograms is of great importance since they are considered the unique sources that provide quantitative information of historical earthquakes. Modern techniques of seismology require digital forms of seismograms that are essentially a sequence of time-amplitude pairs. However, the historical seismograms, after scanned into computers, are two dimensional arrays. Each element of the arrays contains the grayscale value or RGB value of the corresponding pixel. The problem of digitizing historical seismograms, referred to as converting historical seismograms to digital seismograms, can be formulated as an inverse problem that generating sequences of time-amplitude pairs from a two dimension arrays. This problem has infinite solutions. The algorithm for automatic digitization of historical seismogram presented considers several features of seismograms, including continuity, smoothness of the seismic traces as the prior information, and assumes that the amplitude is a single-valued function of time. An interactive program based on the algorithm is also presented. The program is developed using Matlab GUI and has both automatic and manual modality digitization. Users can easily switch between them, and try different combinations to get the optimal results. Several examples are given to illustrate the results of digitizing seismograms using the program, including a photographic record and a wide-angle reflection/refraction seismogram. Digitized result of the program (redrawn using Golden Software Surfer for high resolution image). (a) shows the result of automatic digitization, and (b) is the result after manual correction.

A high fidelity real-time simulation of a small turboshaft engine

NASA Technical Reports Server (NTRS)

Ballin, Mark G.

1988-01-01

A high-fidelity component-type model and real-time digital simulation of the General Electric T700-GE-700 turboshaft engine were developed for use with current generation real-time blade-element rotor helicopter simulations. A control system model based on the specification fuel control system used in the UH-60A Black Hawk helicopter is also presented. The modeling assumptions and real-time digital implementation methods particular to the simulation of small turboshaft engines are described. The validity of the simulation is demonstrated by comparison with analysis-oriented simulations developed by the manufacturer, available test data, and flight-test time histories.

Evaluating planetary digital terrain models-The HRSC DTM test

USGS Publications Warehouse

Heipke, C.; Oberst, J.; Albertz, J.; Attwenger, M.; Dorninger, P.; Dorrer, E.; Ewe, M.; Gehrke, S.; Gwinner, K.; Hirschmuller, H.; Kim, J.R.; Kirk, R.L.; Mayer, H.; Muller, Jan-Peter; Rengarajan, R.; Rentsch, M.; Schmidt, R.; Scholten, F.; Shan, J.; Spiegel, M.; Wahlisch, M.; Neukum, G.

2007-01-01

The High Resolution Stereo Camera (HRSC) has been orbiting the planet Mars since January 2004 onboard the European Space Agency (ESA) Mars Express mission and delivers imagery which is being used for topographic mapping of the planet. The HRSC team has conducted a systematic inter-comparison of different alternatives for the production of high resolution digital terrain models (DTMs) from the multi look HRSC push broom imagery. Based on carefully chosen test sites the test participants have produced DTMs which have been subsequently analysed in a quantitative and a qualitative manner. This paper reports on the results obtained in this test. ?? 2007 Elsevier Ltd. All rights reserved.

Phase noise optimization in temporal phase-shifting digital holography with partial coherence light sources and its application in quantitative cell imaging.

PubMed

Remmersmann, Christian; Stürwald, Stephan; Kemper, Björn; Langehanenberg, Patrik; von Bally, Gert

2009-03-10

In temporal phase-shifting-based digital holographic microscopy, high-resolution phase contrast imaging requires optimized conditions for hologram recording and phase retrieval. To optimize the phase resolution, for the example of a variable three-step algorithm, a theoretical analysis on statistical errors, digitalization errors, uncorrelated errors, and errors due to a misaligned temporal phase shift is carried out. In a second step the theoretically predicted results are compared to the measured phase noise obtained from comparative experimental investigations with several coherent and partially coherent light sources. Finally, the applicability for noise reduction is demonstrated by quantitative phase contrast imaging of pancreas tumor cells.

Capacitance-digital and impedance converter as electrical tomography measurement system for biological tissue

NASA Astrophysics Data System (ADS)

Ikhsanti, Mila Izzatul; Bouzida, Rana; Wijaya, Sastra Kusuma; Rohmadi, Muttakin, Imamul; Taruno, Warsito P.

2017-02-01

This research aims to explore the feasibility of capacitance-digital converter and impedance converter for measurement module in electrical capacitance tomography (ECT) system. ECT sensor used was a cylindrical sensor having 8 electrodes. Absolute capacitance measurement system based on Sigma Delta Capacitance-to-Digital-Converter AD7746 has been shown to produce measurement with high resolution. Whereas, capacitance measurement with wide range of frequency is possible using Impedance Converter AD5933. Comparison of measurement accuracy by both AD7746 and AD5933 with reference of LCR meter was evaluated. Biological matters represented in water and oil were treated as object reconstructed into image using linear back projection (LBP) algorithm.

A digital intensity stabilization system for HeNe laser

NASA Astrophysics Data System (ADS)

Wei, Zhimeng; Lu, Guangfeng; Yang, Kaiyong; Long, Xingwu; Huang, Yun

2012-02-01

A digital intensity stabilization system for HeNe laser is developed. Based on a switching power IC to design laser power supply and a general purpose microcontroller to realize digital PID control, the system constructs a closed loop to stabilize the laser intensity by regulating its discharge current. The laser tube is made of glass ceramics and its integrated structure is steady enough to eliminate intensity fluctuations at high frequency and attenuates all intensity fluctuations, and this makes it easy to tune the control loop. The control loop between discharge current and photodiode voltage eliminates the long-term drifts. The intensity stability of the HeNe laser with this system is 0.014% over 12 h.

Advanced optical network architecture for integrated digital avionics

NASA Astrophysics Data System (ADS)

Morgan, D. Reed

1996-12-01

For the first time in the history of avionics, the network designer now has a choice in selecting the media that interconnects the sources and sinks of digital data on aircraft. Electrical designs are already giving way to photonics in application areas where the data rate times distance product is large or where special design requirements such as low weight or EMI considerations are critical. Future digital avionic architectures will increasingly favor the use of photonic interconnects as network data rates of one gigabit/second and higher are needed to support real-time operation of high-speed integrated digital processing. As the cost of optical network building blocks is reduced and as temperature-rugged laser sources are matured, metal interconnects will be forced to retreat to applications spanning shorter and shorter distances. Although the trend is already underway, the widespread use of digital optics will first occur at the system level, where gigabit/second, real-time interconnects between sensors, processors, mass memories and displays separated by a least of few meters will be required. The application of photonic interconnects for inter-printed wiring board signalling across the backplane will eventually find application for gigabit/second applications since signal degradation over copper traces occurs before one gigabit/second and 0.5 meters are reached. For the foreseeable future however, metal interconnects will continue to be used to interconnect devices on printed wiring boards since 5 gigabit/second signals can be sent over metal up to around 15 centimeters. Current-day applications of optical interconnects at the system level are described and a projection of how advanced optical interconnect technology will be driven by the use of high speed integrated digital processing on future aircraft is presented. The recommended advanced network for application in the 2010 time frame is a fiber-based system with a signalling speed of around 2-3 gigabits per second. This switch-based unified network will interconnect sensors, displays, mass memory and controls and displays to computer modules within the processing complex. The characteristics of required building blocks needed for the future are described. These building blocks include the fiber, an optical switch, a laser-based transceiver, blind-mate connectors and an optical backplane.

Drawing for Traffic Marking Using Bidirectional Gradient-Based Detection with MMS LIDAR Intensity

NASA Astrophysics Data System (ADS)

Takahashi, G.; Takeda, H.; Nakamura, K.

2016-06-01

Recently, the development of autonomous cars is accelerating on the integration of highly advanced artificial intelligence, which increases demand for a digital map with high accuracy. In particular, traffic markings are required to be precisely digitized since automatic driving utilizes them for position detection. To draw traffic markings, we benefit from Mobile Mapping Systems (MMS) equipped with high-density Laser imaging Detection and Ranging (LiDAR) scanners, which produces large amount of data efficiently with XYZ coordination along with reflectance intensity. Digitizing this data, on the other hand, conventionally has been dependent on human operation, which thus suffers from human errors, subjectivity errors, and low reproductivity. We have tackled this problem by means of automatic extraction of traffic marking, which partially accomplished to draw several traffic markings (G. Takahashi et al., 2014). The key idea of the method was extracting lines using the Hough transform strategically focused on changes in local reflection intensity along scan lines. However, it failed to extract traffic markings properly in a densely marked area, especially when local changing points are close each other. In this paper, we propose a bidirectional gradient-based detection method where local changing points are labelled with plus or minus group. Given that each label corresponds to the boundary between traffic markings and background, we can identify traffic markings explicitly, meaning traffic lines are differentiated correctly by the proposed method. As such, our automated method, a highly accurate and non-human-operator-dependent method using bidirectional gradient-based algorithm, can successfully extract traffic lines composed of complex shapes such as a cross walk, resulting in minimizing cost and obtaining highly accurate results.

Watermarking protocols for authentication and ownership protection based on timestamps and holograms

NASA Astrophysics Data System (ADS)

Dittmann, Jana; Steinebach, Martin; Croce Ferri, Lucilla

2002-04-01

Digital watermarking has become an accepted technology for enabling multimedia protection schemes. One problem here is the security of these schemes. Without a suitable framework, watermarks can be replaced and manipulated. We discuss different protocols providing security against rightful ownership attacks and other fraud attempts. We compare the characteristics of existing protocols for different media like direct embedding or seed based and required attributes of the watermarking technology like robustness or payload. We introduce two new media independent protocol schemes for rightful ownership authentication. With the first scheme we ensure security of digital watermarks used for ownership protection with a combination of two watermarks: first watermark of the copyright holder and a second watermark from a Trusted Third Party (TTP). It is based on hologram embedding and the watermark consists of e.g. a company logo. As an example we use digital images and specify the properties of the embedded additional security information. We identify components necessary for the security protocol like timestamp, PKI and cryptographic algorithms. The second scheme is used for authentication. It is designed for invertible watermarking applications which require high data integrity. We combine digital signature schemes and digital watermarking to provide a public verifiable integrity. The original data can only be reproduced with a secret key. Both approaches provide solutions for copyright and authentication watermarking and are introduced for image data but can be easily adopted for video and audio data as well.

Ultra-fast quantitative imaging using ptychographic iterative engine based digital micro-mirror device

NASA Astrophysics Data System (ADS)

Sun, Aihui; Tian, Xiaolin; Kong, Yan; Jiang, Zhilong; Liu, Fei; Xue, Liang; Wang, Shouyu; Liu, Cheng

2018-01-01

As a lensfree imaging technique, ptychographic iterative engine (PIE) method can provide both quantitative sample amplitude and phase distributions avoiding aberration. However, it requires field of view (FoV) scanning often relying on mechanical translation, which not only slows down measuring speed, but also introduces mechanical errors decreasing both resolution and accuracy in retrieved information. In order to achieve high-accurate quantitative imaging with fast speed, digital micromirror device (DMD) is adopted in PIE for large FoV scanning controlled by on/off state coding by DMD. Measurements were implemented using biological samples as well as USAF resolution target, proving high resolution in quantitative imaging using the proposed system. Considering its fast and accurate imaging capability, it is believed the DMD based PIE technique provides a potential solution for medical observation and measurements.

Continuous-tone applications in digital hard-copy output devices

NASA Astrophysics Data System (ADS)

Saunders, Jeffrey C.

1990-11-01

Dye diffusion technology has made a recent entry into the hardcopy printer arena making it now possible to achieve near-photographic quality images from digital raster image data. Whereas the majority of low cost printers utilizing ink-jet, thermal wax, or dotmatrix technologies advertise high resolution printheads, the restrictions which dithering algorithms apply to these inherently binary printing systems force them to sacrifice spatial resolution capability for tone scale reproduction. Dye diffusion technology allows a fully continuous range of density at each pixel location thus preserving the full spatial resolution capability of the printhead; spatial resolution is not sacrificed for tone scale. This results in images whose quality is far superior to the ink-jet or wax-transfer products; image quality so high in fact, to the unaided eye, dye diffusion images are indistinguishable from their silver-halide counterparts. Eastman Kodak Co. offers a highly refined application of dye diffusion technology in the Kodak XL 7700 Digital Continuous Tone Printer and Kodak EKTATHERM media products. The XL . 7700 Printer represents a serious alternative to expensive laser-based film recorders for applications which require high quality image output from digital data files. This paper presents an explanation of dye diffusion printing, what distinguishes it from other technologies, sensitometric control and image quality parameters, and applications within the industry, particularly that of Airborne Reconnaissance and Remote Sensing.

A Web-Based Video Digitizing System for the Study of Projectile Motion.

ERIC Educational Resources Information Center

Chow, John W.; Carlton, Les G.; Ekkekakis, Panteleimon; Hay, James G.

2000-01-01

Discusses advantages of a video-based, digitized image system for the study and analysis of projectile motion in the physics laboratory. Describes the implementation of a web-based digitized video system. (WRM)

A Fast lattice-based polynomial digital signature system for m-commerce

NASA Astrophysics Data System (ADS)

Wei, Xinzhou; Leung, Lin; Anshel, Michael

2003-01-01

The privacy and data integrity are not guaranteed in current wireless communications due to the security hole inside the Wireless Application Protocol (WAP) version 1.2 gateway. One of the remedies is to provide an end-to-end security in m-commerce by applying application level security on top of current WAP1.2. The traditional security technologies like RSA and ECC applied on enterprise's server are not practical for wireless devices because wireless devices have relatively weak computation power and limited memory compared with server. In this paper, we developed a lattice based polynomial digital signature system based on NTRU's Polynomial Authentication and Signature Scheme (PASS), which enabled the feasibility of applying high-level security on both server and wireless device sides.

An Automatic and Robust Algorithm of Reestablishment of Digital Dental Occlusion

PubMed Central

Chang, Yu-Bing; Xia, James J.; Gateno, Jaime; Xiong, Zixiang; Zhou, Xiaobo; Wong, Stephen T. C.

2017-01-01

In the field of craniomaxillofacial (CMF) surgery, surgical planning can be performed on composite 3-D models that are generated by merging a computerized tomography scan with digital dental models. Digital dental models can be generated by scanning the surfaces of plaster dental models or dental impressions with a high-resolution laser scanner. During the planning process, one of the essential steps is to reestablish the dental occlusion. Unfortunately, this task is time-consuming and often inaccurate. This paper presents a new approach to automatically and efficiently reestablish dental occlusion. It includes two steps. The first step is to initially position the models based on dental curves and a point matching technique. The second step is to reposition the models to the final desired occlusion based on iterative surface-based minimum distance mapping with collision constraints. With linearization of rotation matrix, the alignment is modeled by solving quadratic programming. The simulation was completed on 12 sets of digital dental models. Two sets of dental models were partially edentulous, and another two sets have first premolar extractions for orthodontic treatment. Two validation methods were applied to the articulated models. The results show that using our method, the dental models can be successfully articulated with a small degree of deviations from the occlusion achieved with the gold-standard method. PMID:20529735

A randomized trial comparing digital and live lecture formats [ISRCTN40455708.

PubMed

Solomon, David J; Ferenchick, Gary S; Laird-Fick, Heather S; Kavanaugh, Kevin

2004-11-29

Medical education is increasingly being conducted in community-based teaching sites at diverse locations, making it difficult to provide a consistent curriculum. We conducted a randomized trial to assess whether students who viewed digital lectures would perform as well on a measure of cognitive knowledge as students who viewed live lectures. Students' perceptions of the digital lecture format and their opinion as whether a digital lecture format could serve as an adequate replacement for live lectures was also assessed. Students were randomized to either attend a lecture series at our main campus or view digital versions of the same lectures at community-based teaching sites. Both groups completed the same examination based on the lectures, and the group viewing the digital lectures completed a feedback form on the digital format. There were no differences in performance as measured by means or average rank. Despite technical problems, the students who viewed the digital lectures overwhelmingly felt the digital lectures could replace live lectures. This study provides preliminary evidence digital lectures can be a viable alternative to live lectures as a means of delivering didactic presentations in a community-based setting.

A randomized trial comparing digital and live lecture formats [ISRCTN40455708

PubMed Central

Solomon, David J; Ferenchick, Gary S; Laird-Fick, Heather S; Kavanaugh, Kevin

2004-01-01

Background Medical education is increasingly being conducted in community-based teaching sites at diverse locations, making it difficult to provide a consistent curriculum. We conducted a randomized trial to assess whether students who viewed digital lectures would perform as well on a measure of cognitive knowledge as students who viewed live lectures. Students' perceptions of the digital lecture format and their opinion as whether a digital lecture format could serve as an adequate replacement for live lectures was also assessed. Methods Students were randomized to either attend a lecture series at our main campus or view digital versions of the same lectures at community-based teaching sites. Both groups completed the same examination based on the lectures, and the group viewing the digital lectures completed a feedback form on the digital format. Results There were no differences in performance as measured by means or average rank. Despite technical problems, the students who viewed the digital lectures overwhelmingly felt the digital lectures could replace live lectures. Conclusions This study provides preliminary evidence digital lectures can be a viable alternative to live lectures as a means of delivering didactic presentations in a community-based setting. PMID:15569389

Evaluating Multi-Input/Multi-Output Digital Control Systems

NASA Technical Reports Server (NTRS)

Pototzky, Anthony S.; Wieseman, Carol D.; Hoadley, Sherwood T.; Mukhopadhyay, Vivek

1994-01-01

Controller-performance-evaluation (CPE) methodology for multi-input/multi-output (MIMO) digital control systems developed. Procedures identify potentially destabilizing controllers and confirm satisfactory performance of stabilizing ones. Methodology generic and used in many types of multi-loop digital-controller applications, including digital flight-control systems, digitally controlled spacecraft structures, and actively controlled wind-tunnel models. Also applicable to other complex, highly dynamic digital controllers, such as those in high-performance robot systems.

A cylindrical SPECT camera with de-centralized readout scheme

NASA Astrophysics Data System (ADS)

Habte, F.; Stenström, P.; Rillbert, A.; Bousselham, A.; Bohm, C.; Larsson, S. A.

2001-09-01

An optimized brain single photon emission computed tomograph (SPECT) camera is being designed at Stockholm University and Karolinska Hospital. The design goal is to achieve high sensitivity, high-count rate and high spatial resolution. The sensitivity is achieved by using a cylindrical crystal, which gives a closed geometry with large solid angles. A de-centralized readout scheme where only a local environment around the light excitation is readout supports high-count rates. The high resolution is achieved by using an optimized crystal configuration. A 12 mm crystal plus 12 mm light guide combination gave an intrinsic spatial resolution better than 3.5 mm (140 keV) in a prototype system. Simulations show that a modified configuration can improve this value. A cylindrical configuration with a rotating collimator significantly simplifies the mechanical design of the gantry. The data acquisition and control system uses early digitization and subsequent digital signal processing to extract timing and amplitude information, and monitors the position of the collimator. The readout system consists of 12 or more modules each based on programmable logic and a digital signal processor. The modules send data to a PC file server-reconstruction engine via a Firewire (IEEE-1394) network.

Low-cost, portable, robust and high-resolution single-camera stereo-DIC system and its application in high-temperature deformation measurements

NASA Astrophysics Data System (ADS)

Chi, Yuxi; Yu, Liping; Pan, Bing

2018-05-01

A low-cost, portable, robust and high-resolution single-camera stereo-digital image correlation (stereo-DIC) system for accurate surface three-dimensional (3D) shape and deformation measurements is described. This system adopts a single consumer-grade high-resolution digital Single Lens Reflex (SLR) camera and a four-mirror adaptor, rather than two synchronized industrial digital cameras, for stereo image acquisition. In addition, monochromatic blue light illumination and coupled bandpass filter imaging are integrated to ensure the robustness of the system against ambient light variations. In contrast to conventional binocular stereo-DIC systems, the developed pseudo-stereo-DIC system offers the advantages of low cost, portability, robustness against ambient light variations, and high resolution. The accuracy and precision of the developed single SLR camera-based stereo-DIC system were validated by measuring the 3D shape of a stationary sphere along with in-plane and out-of-plane displacements of a translated planar plate. Application of the established system to thermal deformation measurement of an alumina ceramic plate and a stainless-steel plate subjected to radiation heating was also demonstrated.

Effects of mobile and digital support for a structured, competency-based curriculum in neurosurgery residency education.

PubMed

Gonzalez, Nestor R; Dusick, Joshua R; Martin, Neil A

2012-07-01

Changes in neurosurgical practice and graduate medical education impose new challenges for training programs. We present our experience providing neurosurgical residents with digital and mobile educational resources in support of the departmental academic activities. A weekly mandatory conference program for all clinical residents based on the Accreditation Council for Graduate Medical Education competencies, held in protected time, was introduced. Topics were taught through didactic sessions and case discussions. Faculty and residents prepare high-quality presentations, equivalent to peer-review leading papers or case reports. Presentations are videorecorded, stored in a digital library, and broadcasted through our Website and iTunes U. Residents received mobile tablet devices with remote access to the digital library, applications for document/video management, and interactive teaching tools. Residents responded to an anonymous survey, and performances on the Self-Assessment in Neurological Surgery examination before and after the intervention were compared. Ninety-two percent reported increased time used to study outside the hospital and attributed the habit change to the introduction of mobile devices; 67% used the electronic tablets as the primary tool to access the digital library, followed by 17% hospital computers, 8% home computers, and 8% personal laptops. Forty-two percent have submitted operative videos, cases, and documents to the library. One year after introducing the program, results of the Congress of Neurological Surgeons-Self-Assessment in Neurological Surgery examination showed a statistically significant improvement in global scoring and improvement in 16 of the 18 individual areas evaluated, 6 of which reached statistical significance. A structured, competency-based neurosurgical education program supported with digital and mobile resources improved reading habits among residents and performance on the Congress of Neurological Surgeons-Self-Assessment in Neurological Surgery examination.

Advanced IR System For Supersonic Boundary Layer Transition Flight Experiment

NASA Technical Reports Server (NTRS)

Banks, Daniel W.

2008-01-01

Infrared thermography is a preferred method investigating transition in flight: a) Global and non-intrusive; b) Can also be used to visualize and characterize other fluid mechanic phenomena such as shock impingement, separation etc. F-15 based system was updated with new camera and digital video recorder to support high Reynolds number transition tests. Digital Recording improves image quality and analysis capability and allows for accurate quantitative (temperature) measurements and greater enhancement through image processing allows analysis of smaller scale phenomena.

The Coming of Digital Desktop Media.

ERIC Educational Resources Information Center

Galbreath, Jeremy

1992-01-01

Discusses the movement toward digital-based platforms including full-motion video for multimedia products. Hardware- and software-based compression techniques for digital data storage are considered, and a chart summarizes features of Digital Video Interactive, Moving Pictures Experts Group, P x 64, Joint Photographic Experts Group, Apple…

Digital Astronaut Photography: A Discovery Dataset for Archaeology

NASA Technical Reports Server (NTRS)

Stefanov, William L.

2010-01-01

Astronaut photography acquired from the International Space Station (ISS) using commercial off-the-shelf cameras offers a freely-accessible source for high to very high resolution (4-20 m/pixel) visible-wavelength digital data of Earth. Since ISS Expedition 1 in 2000, over 373,000 images of the Earth-Moon system (including land surface, ocean, atmospheric, and lunar images) have been added to the Gateway to Astronaut Photography of Earth online database (http://eol.jsc.nasa.gov ). Handheld astronaut photographs vary in look angle, time of acquisition, solar illumination, and spatial resolution. These attributes of digital astronaut photography result from a unique combination of ISS orbital dynamics, mission operations, camera systems, and the individual skills of the astronaut. The variable nature of astronaut photography makes the dataset uniquely useful for archaeological applications in comparison with more traditional nadir-viewing multispectral datasets acquired from unmanned orbital platforms. For example, surface features such as trenches, walls, ruins, urban patterns, and vegetation clearing and regrowth patterns may be accentuated by low sun angles and oblique viewing conditions (Fig. 1). High spatial resolution digital astronaut photographs can also be used with sophisticated land cover classification and spatial analysis approaches like Object Based Image Analysis, increasing the potential for use in archaeological characterization of landscapes and specific sites.

A scalable self-priming fractal branching microchannel net chip for digital PCR.

PubMed

Zhu, Qiangyuan; Xu, Yanan; Qiu, Lin; Ma, Congcong; Yu, Bingwen; Song, Qi; Jin, Wei; Jin, Qinhan; Liu, Jinyu; Mu, Ying

2017-05-02

As an absolute quantification method at the single-molecule level, digital PCR has been widely used in many bioresearch fields, such as next generation sequencing, single cell analysis, gene editing detection and so on. However, existing digital PCR methods still have some disadvantages, including high cost, sample loss, and complicated operation. In this work, we develop an exquisite scalable self-priming fractal branching microchannel net digital PCR chip. This chip with a special design inspired by natural fractal-tree systems has an even distribution and 100% compartmentalization of the sample without any sample loss, which is not available in existing chip-based digital PCR methods. A special 10 nm nano-waterproof layer was created to prevent the solution from evaporating. A vacuum pre-packaging method called self-priming reagent introduction is used to passively drive the reagent flow into the microchannel nets, so that this chip can realize sequential reagent loading and isolation within a couple of minutes, which is very suitable for point-of-care detection. When the number of positive microwells stays in the range of 100 to 4000, the relative uncertainty is below 5%, which means that one panel can detect an average of 101 to 15 374 molecules by the Poisson distribution. This chip is proved to have an excellent ability for single molecule detection and quantification of low expression of hHF-MSC stem cell markers. Due to its potential for high throughput, high density, low cost, lack of sample and reagent loss, self-priming even compartmentalization and simple operation, we envision that this device will significantly expand and extend the application range of digital PCR involving rare samples, liquid biopsy detection and point-of-care detection with higher sensitivity and accuracy.

Some Psychometric and Design Implications of Game-Based Learning Analytics

ERIC Educational Resources Information Center

Gibson, David; Clarke-Midura, Jody

2013-01-01

The rise of digital game and simulation-based learning applications has led to new approaches in educational measurement that take account of patterns in time, high resolution paths of action, and clusters of virtual performance artifacts. The new approaches, which depart from traditional statistical analyses, include data mining, machine…

Long-Term Instrumentation, Information, and Control Systems (II&C) Modernization Future Vision and Strategy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kenneth Thomas

2012-02-01

Life extension beyond 60 years for the U.S operating nuclear fleet requires that instrumentation and control (I&C) systems be upgraded to address aging and reliability concerns. It is impractical for the legacy systems based on 1970's vintage technology operate over this extended time period. Indeed, utilities have successfully engaged in such replacements when dictated by these operational concerns. However, the replacements have been approached in a like-for-like manner, meaning that they do not take advantage of the inherent capabilities of digital technology to improve business functions. And so, the improvement in I&C system performance has not translated to bottom-line performancemore » improvement for the fleet. Therefore, wide-scale modernization of the legacy I&C systems could prove to be cost-prohibitive unless the technology is implemented in a manner to enable significant business innovation as a means of off-setting the cost of upgrades. A Future Vision of a transformed nuclear plant operating model based on an integrated digital environment has been developed as part of the Advanced Instrumentation, Information, and Control (II&C) research pathway, under the Light Water Reactor (LWR) Sustainability Program. This is a research and development program sponsored by the U.S. Department of Energy (DOE), performed in close collaboration with the nuclear utility industry, to provide the technical foundations for licensing and managing the long-term, safe and economical operation of current nuclear power plants. DOE's program focus is on longer-term and higher-risk/reward research that contributes to the national policy objectives of energy security and environmental security . The Advanced II&C research pathway is being conducted by the Idaho National Laboratory (INL). The Future Vision is based on a digital architecture that encompasses all aspects of plant operations and support, integrating plant systems, plant work processes, and plant workers in a seamless digital environment to enhance nuclear safety, increase productivity, and improve overall plant performance. The long-term goal is to transform the operating model of the nuclear power plants (NPP)s from one that is highly reliant on a large staff performing mostly manual activities to an operating model based on highly integrated technology with a smaller staff. This digital transformation is critical to addressing an array of issues facing the plants, including aging of legacy analog systems, potential shortage of technical workers, ever-increasing expectations for nuclear safety improvement, and relentless pressure to reduce cost. The Future Vision is based on research is being conducted in the following major areas of plant function: (1) Highly integrated control rooms; (2) Highly automated plant; (3) Integrated operations; (4) Human performance improvement for field workers; and (5) Outage safety and efficiency. Pilot projects will be conducted in each of these areas as the means for industry to collectively integrate these new technologies into nuclear plant work activities. The pilot projects introduce new digital technologies into the nuclear plant operating environment at host operating plants to demonstrate and validate them for production usage. In turn, the pilot project technologies serve as the stepping stones to the eventual seamless digital environment as described in the Future Vision.« less

Long-Term Instrumentation, Information, and Control Systems (II&C) Modernization Future Vision and Strategy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kenneth Thomas; Bruce Hallbert

2013-02-01

Life extension beyond 60 years for the U.S operating nuclear fleet requires that instrumentation and control (I&C) systems be upgraded to address aging and reliability concerns. It is impractical for the legacy systems based on 1970’s vintage technology operate over this extended time period. Indeed, utilities have successfully engaged in such replacements when dictated by these operational concerns. However, the replacements have been approached in a like-for-like manner, meaning that they do not take advantage of the inherent capabilities of digital technology to improve business functions. And so, the improvement in I&C system performance has not translated to bottom-line performancemore » improvement for the fleet. Therefore, wide-scale modernization of the legacy I&C systems could prove to be cost-prohibitive unless the technology is implemented in a manner to enable significant business innovation as a means of off-setting the cost of upgrades. A Future Vision of a transformed nuclear plant operating model based on an integrated digital environment has been developed as part of the Advanced Instrumentation, Information, and Control (II&C) research pathway, under the Light Water Reactor (LWR) Sustainability Program. This is a research and development program sponsored by the U.S. Department of Energy (DOE), performed in close collaboration with the nuclear utility industry, to provide the technical foundations for licensing and managing the long-term, safe and economical operation of current nuclear power plants. DOE’s program focus is on longer-term and higher-risk/reward research that contributes to the national policy objectives of energy security and environmental security . The Advanced II&C research pathway is being conducted by the Idaho National Laboratory (INL). The Future Vision is based on a digital architecture that encompasses all aspects of plant operations and support, integrating plant systems, plant work processes, and plant workers in a seamless digital environment to enhance nuclear safety, increase productivity, and improve overall plant performance. The long-term goal is to transform the operating model of the nuclear power plants (NPP)s from one that is highly reliant on a large staff performing mostly manual activities to an operating model based on highly integrated technology with a smaller staff. This digital transformation is critical to addressing an array of issues facing the plants, including aging of legacy analog systems, potential shortage of technical workers, ever-increasing expectations for nuclear safety improvement, and relentless pressure to reduce cost. The Future Vision is based on research is being conducted in the following major areas of plant function: 1. Highly integrated control rooms 2. Highly automated plant 3. Integrated operations 4. Human performance improvement for field workers 5. Outage safety and efficiency. Pilot projects will be conducted in each of these areas as the means for industry to collectively integrate these new technologies into nuclear plant work activities. The pilot projects introduce new digital technologies into the nuclear plant operating environment at host operating plants to demonstrate and validate them for production usage. In turn, the pilot project technologies serve as the stepping stones to the eventual seamless digital environment as described in the Future Vision.« less

A functional language approach in high-speed digital simulation

NASA Technical Reports Server (NTRS)

Ercegovac, M. D.; Lu, S.-L.

1983-01-01

A functional programming approach for a multi-microprocessor architecture is presented. The language, based on Backus FP, its intermediate form and the translation process are discussed and illustrated with an example. The approach allows performance analysis to be performed at a high level as an aid in program partitioning.

Highly linear, sensitive analog-to-digital converter

NASA Technical Reports Server (NTRS)

Cox, J.; Finley, W. R.

1969-01-01

Analog-to-digital converter converts 10 volt full scale input signal into 13 bit digital output. Advantages include high sensitivity, linearity, low quantitizing error, high resistance to mechanical shock and vibration loads, and temporary data storage capabilities.

The role of digital sample information within the digital geoscience infrastructure: a pragmatic approach

NASA Astrophysics Data System (ADS)

Howe, Michael

2014-05-01

Much of the digital geological information on the composition, properties and dynamics of the subsurface is based ultimately on physical samples, many of which are archived to provide a basis for the information. Online metadata catalogues of these collections have now been available for many years. Many of these are institutional and tightly focussed, with UK examples including the British Geological Survey's (BGS) palaeontological samples database, PalaeoSaurus (http://www.bgs.ac.uk/palaeosaurus/), and mineralogical and petrological sample database, Britrocks (http://www.bgs.ac.uk/data/britrocks.html) . There are now a growing number of international sample metadata databases, including The Palaeobiology Database (http://paleobiodb.org/) and SESAR, the IGSN (International Geo Sample Number) database (http://www.geosamples.org/catalogsearch/ ). More recently the emphasis has moved beyond metadata (locality, identification, age, citations, etc) to digital imagery, with the intention of providing the user with at least enough information to determine whether viewing the sample would be worthwhile. Recent BGS examples include high resolution (e.g. 7216 x 5412 pixel) hydrocarbon well core images (http://www.bgs.ac.uk/data/offshoreWells/wells.cfc?method=searchWells) , high resolution rock thin section images (e.g. http://www.largeimages.bgs.ac.uk/iip/britrocks.html?id=290000/291739 ) and building stone images (http://geoscenic.bgs.ac.uk/asset-bank/action/browseItems?categoryId=1547&categoryTypeId=1) . This has been developed further with high resolution stereo images. The Jisc funded GB3D type fossils online project delivers these as red-cyan anaglyphs (http://www.3d-fossils.ac.uk/). More innovatively, the GB3D type fossils project has laser scanned several thousand type fossils and the resulting 3d-digital models are now being delivered through the online portal. Importantly, this project also represents collaboration between the BGS, Oxford and Cambridge Universities, the National Museums of Wales, and numerous other national, local and regional museums. The lack of currently accepted international standards and infrastructures for the delivery of high resolution images and 3d-digital models has necessitated the BGS in developing or selecting its own. Most high resolution images have been delivered using the JPEG 2000 format because of its quality and speed. Digital models have been made available in both .PLY and .OBJ format because of their respective efficient file size, and flexibility. Consideration must now be given to European and international standards and infrastructures for the delivery of high resolution images and 3d-digital models.

Large scale digital atlases in neuroscience

NASA Astrophysics Data System (ADS)

Hawrylycz, M.; Feng, D.; Lau, C.; Kuan, C.; Miller, J.; Dang, C.; Ng, L.

2014-03-01

Imaging in neuroscience has revolutionized our current understanding of brain structure, architecture and increasingly its function. Many characteristics of morphology, cell type, and neuronal circuitry have been elucidated through methods of neuroimaging. Combining this data in a meaningful, standardized, and accessible manner is the scope and goal of the digital brain atlas. Digital brain atlases are used today in neuroscience to characterize the spatial organization of neuronal structures, for planning and guidance during neurosurgery, and as a reference for interpreting other data modalities such as gene expression and connectivity data. The field of digital atlases is extensive and in addition to atlases of the human includes high quality brain atlases of the mouse, rat, rhesus macaque, and other model organisms. Using techniques based on histology, structural and functional magnetic resonance imaging as well as gene expression data, modern digital atlases use probabilistic and multimodal techniques, as well as sophisticated visualization software to form an integrated product. Toward this goal, brain atlases form a common coordinate framework for summarizing, accessing, and organizing this knowledge and will undoubtedly remain a key technology in neuroscience in the future. Since the development of its flagship project of a genome wide image-based atlas of the mouse brain, the Allen Institute for Brain Science has used imaging as a primary data modality for many of its large scale atlas projects. We present an overview of Allen Institute digital atlases in neuroscience, with a focus on the challenges and opportunities for image processing and computation.

Development of high precision digital driver of acoustic-optical frequency shifter for ROG

NASA Astrophysics Data System (ADS)

Zhang, Rong; Kong, Mei; Xu, Yameng

2016-10-01

We develop a high precision digital driver of the acoustic-optical frequency shifter (AOFS) based on the parallel direct digital synthesizer (DDS) technology. We use an atomic clock as the phase-locked loop (PLL) reference clock, and the PLL is realized by a dual digital phase-locked loop. A DDS sampling clock up to 320 MHz with a frequency stability as low as 10-12 Hz is obtained. By constructing the RF signal measurement system, it is measured that the frequency output range of the AOFS-driver is 52-58 MHz, the center frequency of the band-pass filter is 55 MHz, the ripple in the band is less than 1 dB@3MHz, the single channel output power is up to 0.3 W, the frequency stability is 1 ppb (1 hour duration), and the frequency-shift precision is 0.1 Hz. The obtained frequency stability has two orders of improvement compared to that of the analog AOFS-drivers. For the designed binary frequency shift keying (2-FSK) and binary phase shift keying (2-PSK) modulation system, the demodulating frequency of the input TTL synchronous level signal is up to 10 kHz. The designed digital-bus coding/decoding system is compatible with many conventional digital bus protocols. It can interface with the ROG signal detecting software through the integrated drive electronics (IDE) and exchange data with the two DDS frequency-shift channels through the signal detecting software.

Development and Evaluation of Digital Game-Based Training for Managers to Promote Employee Mental Health and Reduce Mental Illness Stigma at Work: Quasi-Experimental Study of Program Effectiveness

PubMed Central

Birner, Ulrich Walter; Oberhauser, Cornelia; Nowak, Dennis; Sabariego, Carla

2017-01-01

Background To counteract the negative impact of mental health problems on business, organizations are increasingly investing in mental health intervention measures. However, those services are often underused, which, to a great extent, can be attributed to fear of stigmatization. Nevertheless, so far only a few workplace interventions have specifically targeted stigma, and evidence on their effectiveness is limited. Objective The objective of this study was to develop and evaluate a digital game-based training program for managers to promote employee mental health and reduce mental illness stigma at work. Methods We describe the empirical development of Leadership Training in Mental Health Promotion (LMHP), a digital game-based training program for leaders. A 1-group pre-post design and a 3-month follow-up were used for training evaluation. We applied multilevel growth models to investigate change over time in the dependent variables knowledge, attitudes, self-efficacy, and intentions to promote employee mental health in 48 managers of a global enterprise in the United Kingdom. Participants were mainly male (44/48, 92%) and ranged in age from 32 to 58 (mean 46.0, SD 7.2) years. Results We found a positive impact of the Web-based training program on managers’ knowledge of mental health and mental illness (P<.001), on attitudes toward people with mental health problems (P<.01), and on their self-efficacy to deal with mental health situations at work (P<.001), with the exception of intentions to promote employee mental health, which was initially high. Conclusions Results provide first evidence of the effectiveness of LMHP to positively affect managers’ skills to promote employee mental health at work. Furthermore, the high rate of participation in LMHP (48/54, 89%) supports the use of digital game-based interventions to increase user engagement and user experience in mental health programs at work. PMID:28778839

Higher Order Modulation Intersymbol Interference Caused by Traveling-wave Tube Amplifiers

NASA Technical Reports Server (NTRS)

Kory, Carol L.; Andro, Monty; Williams, W. D. (Technical Monitor)

2002-01-01

For the first time, a time-dependent, physics-based computational model has been used to provide a direct description of the effects of the traveling wave tube amplifier (TWTA) on modulated digital signals. The TWT model comprehensively takes into account the effects of frequency dependent AM/AM and AM/PM conversion; gain and phase ripple; drive-induced oscillations; harmonic generation; intermodulation products; and backward waves, Thus, signal integrity can be investigated in the presence of these sources of potential distortion as a function of the physical geometry and operating characteristics of the high power amplifier and the operational digital signal. This method promises superior predictive fidelity compared to methods using TWT models based on swept-amplitude and/or swept-frequency data. First, the TWT model using the three dimensional (3D) electromagnetic code MAFIA is presented. Then, this comprehensive model is used to investigate approximations made in conventional TWT black-box models used in communication system level simulations, To quantitatively demonstrate the effects these approximations have on digital signal performance predictions, including intersymbol interference (ISI), the MAFIA results are compared to the system level analysis tool, Signal Processing, Workstation (SPW), using high order modulation schemes including 16 and 64-QAM.

Intersymbol Interference Investigations Using a 3D Time-Dependent Traveling Wave Tube Model

NASA Technical Reports Server (NTRS)

Kory, Carol L.; Andro, Monty

2002-01-01

For the first time, a time-dependent, physics-based computational model has been used to provide a direct description of the effects of the traveling wave tube amplifier (TWTA) on modulated digital signals. The TWT model comprehensively takes into account the effects of frequency dependent AM/AM and AM/PM conversion; gain and phase ripple; drive-induced oscillations; harmonic generation; intermodulation products; and backward waves. Thus, signal integrity can be investigated in the presence of these sources of potential distortion as a function of the physical geometry and operating characteristics of the high power amplifier and the operational digital signal. This method promises superior predictive fidelity compared to methods using TWT models based on swept- amplitude and/or swept-frequency data. First, the TWT model using the three dimensional (3D) electromagnetic code MAFIA is presented. Then, this comprehensive model is used to investigate approximations made in conventional TWT black-box models used in communication system level simulations. To quantitatively demonstrate the effects these approximations have on digital signal performance predictions, including intersymbol interference (ISI), the MAFIA results are compared to the system level analysis tool, Signal Processing Workstation (SPW), using high order modulation schemes including 16 and 64-QAM.

Digital map and situation surface: a team-oriented multidisplay workspace for network enabled situation analysis

NASA Astrophysics Data System (ADS)

Peinsipp-Byma, E.; Geisler, Jürgen; Bader, Thomas

2009-05-01

System concepts for network enabled image-based ISR (intelligence, surveillance, reconnaissance) is the major mission of Fraunhofer IITB's applied research in the area of defence and security solutions. For the TechDemo08 as part of the NATO CNAD POW Defence against terrorism Fraunhofer IITB advanced a new multi display concept to handle the shear amount and high complexity of ISR data acquired by networked, distributed surveillance systems with the objective to support the generation of a common situation picture. Amount and Complexity of ISR data demands an innovative man-machine interface concept for humans to deal with it. The IITB's concept is the Digital Map & Situation Surface. This concept offers to the user a coherent multi display environment combining a horizontal surface for the situation overview from the bird's eye view, an attached vertical display for collateral information and so-called foveatablets as personalized magic lenses in order to obtain high resolved and role-specific information about a focused areaof- interest and to interact with it. In the context of TechDemo08 the Digital Map & Situation Surface served as workspace for team-based situation visualization and analysis. Multiple sea- and landside surveillance components were connected to the system.

Dynamic spatial filtering using a digital micromirror device for high-speed optical diffraction tomography.

PubMed

Jin, Di; Zhou, Renjie; Yaqoob, Zahid; So, Peter T C

2018-01-08

Optical diffraction tomography (ODT) is an emerging microscopy technique for three-dimensional (3D) refractive index (RI) mapping of transparent specimens. Recently, the digital micromirror device (DMD) based scheme for angle-controlled plane wave illumination has been proposed to improve the imaging speed and stability of ODT. However, undesired diffraction noise always exists in the reported DMD-based illumination scheme, which leads to a limited contrast ratio of the measurement fringe and hence inaccurate RI mapping. Here we present a novel spatial filtering method, based on a second DMD, to dynamically remove the diffraction noise. The reported results illustrate significantly enhanced image quality of the obtained interferograms and the subsequently derived phase maps. And moreover, with this method, we demonstrate mapping of 3D RI distribution of polystyrene beads as well as biological cells with high accuracy. Importantly, with the proper hardware configuration, our method does not compromise the 3D imaging speed advantage promised by the DMD-based illumination scheme. Specifically, we have been able to successfully obtain interferograms at over 1 kHz speed, which is critical for potential high-throughput label-free 3D image cytometry applications.

Modelling prehistoric terrain Models using LiDAR-data: a geomorphological approach

NASA Astrophysics Data System (ADS)

Höfler, Veit; Wessollek, Christine; Karrasch, Pierre

2015-10-01

Terrain surfaces conserve human activities in terms of textures and structures. With reference to archaeological questions, the geological archive is investigated by means of models regarding anthropogenic traces. In doing so, the high-resolution digital terrain model is of inestimable value for the decoding of the archive. The evaluation of these terrain models and the reconstruction of historical surfaces is still a challenging issue. Due to the data collection by means of LiDAR systems (light detection and ranging) and despite their subsequent pre-processing and filtering, recently anthropogenic artefacts are still present in the digital terrain model. Analysis have shown that elements, such as contour lines and channels, can well be extracted from a high-resolution digital terrain model. This way, channels in settlement areas show a clear anthropogenic character. This fact can also be observed for contour lines. Some contour lines representing a possibly natural ground surface and avoid anthropogenic artefacts. Comparable to channels, noticeable patterns of contour lines become visible in areas with anthropogenic artefacts. The presented workflow uses functionalities of ArcGIS and the programming language R.1 The method starts with the extraction of contour lines from the digital terrain model. Through macroscopic analyses based on geomorphological expert knowledge, contour lines are selected representing the natural geomorphological character of the surface. In a first step, points are determined along each contour line in regular intervals. This points and the corresponding height information which is taken from an original digital terrain model is saved as a point cloud. Using the programme library gstat, a variographic analysis and the use of a Kriging-procedure based on this follow.2-4 The result is a digital terrain model filtered considering geomorphological expert knowledge showing no human degradation in terms of artefacts, preserving the landscape-genetic character and can be called a prehistoric terrain model.

The x-ray light valve: a potentially low-cost, digital radiographic imaging system--a liquid crystal cell design for chest radiography.

PubMed

Szeto, Timothy C; Webster, Christie Ann; Koprinarov, Ivaylo; Rowlands, J A

2008-03-01

Digital x-ray radiographic systems are desirable as they offer high quality images which can be processed, transferred, and stored without secondary steps. However, current clinical systems are extraordinarily expensive in comparison to film-based systems. Thus, there is a need for an economical digital imaging system for general radiology. The x-ray light valve (XLV) is a novel digital x-ray detector concept with the potential for high image quality and low cost. The XLV is comprised of a photoconductive detector layer and liquid crystal (LC) cell physically coupled in a sandwich structure. Upon exposure to x rays, charge is collected at the surface of the photoconductor, causing a change in the reflective properties of the LC cell. The visible image so formed can subsequently be digitized with an optical scanner. By choosing the properties of the LC cell in combination with the appropriate photoconductor thickness and bias potentials, the XLV can be optimized for various diagnostic imaging tasks. Specifically for chest radiography, we identified three potentially practical reflective cell designs by selecting from those commonly used in LC display technology. The relationship between reflectance and x-ray exposure (i.e., the characteristic curve) was determined for all three cells using a theoretical model. The results indicate that the reflective electrically controlled birefringence (r-ECB) cell is the preferred choice for chest radiography, provided that the characteristic curve can be shifted towards lower exposures. The feasibility of the shift of the characteristic curve is shown experimentally. The experimental results thus demonstrate that an XLV based on the r-ECB cell design exhibits a characteristic curve suitable for chest radiography.

3D-information fusion from very high resolution satellite sensors

NASA Astrophysics Data System (ADS)

Krauss, T.; d'Angelo, P.; Kuschk, G.; Tian, J.; Partovi, T.

2015-04-01

In this paper we show the pre-processing and potential for environmental applications of very high resolution (VHR) satellite stereo imagery like these from WorldView-2 or Pl'eiades with ground sampling distances (GSD) of half a metre to a metre. To process such data first a dense digital surface model (DSM) has to be generated. Afterwards from this a digital terrain model (DTM) representing the ground and a so called normalized digital elevation model (nDEM) representing off-ground objects are derived. Combining these elevation based data with a spectral classification allows detection and extraction of objects from the satellite scenes. Beside the object extraction also the DSM and DTM can directly be used for simulation and monitoring of environmental issues. Examples are the simulation of floodings, building-volume and people estimation, simulation of noise from roads, wave-propagation for cellphones, wind and light for estimating renewable energy sources, 3D change detection, earthquake preparedness and crisis relief, urban development and sprawl of informal settlements and much more. Also outside of urban areas volume information brings literally a new dimension to earth oberservation tasks like the volume estimations of forests and illegal logging, volume of (illegal) open pit mining activities, estimation of flooding or tsunami risks, dike planning, etc. In this paper we present the preprocessing from the original level-1 satellite data to digital surface models (DSMs), corresponding VHR ortho images and derived digital terrain models (DTMs). From these components we present how a monitoring and decision fusion based 3D change detection can be realized by using different acquisitions. The results are analyzed and assessed to derive quality parameters for the presented method. Finally the usability of 3D information fusion from VHR satellite imagery is discussed and evaluated.

Citizen-Scientist Digitization of a Complex Geologic Map of the McDowell Mountains (Scottsdale, Arizona).

NASA Astrophysics Data System (ADS)

Gruber, D.; Skotnicki, S.; Gootee, B.

2016-12-01

The work of citizen scientists has become very important to researchers doing field work and internet-based projects but has not been widely utilized in digital mapping. The McDowell Mountains - located in Scottsdale, Arizona, at the edge of the basin-and-range province and protected as part of the McDowell Sonoran Preserve - are geologically complex. Until recently, no comprehensive geologic survey of the entire range had been done. Over the last 9 years geologist Steven Skotnicki spent 2000 hours mapping the complex geology of the range. His work, born of personal interest and partially supported by the McDowell Sonoran Conservancy, resulted in highly detailed hand-drawn survey maps. Dr. Skotnicki's work provides important new information and raises interesting research questions about the geology of this range. Citizen scientists of the McDowell Sonoran Conservancy Field Institute digitized Dr. Skotnicki's maps. A team of 10 volunteers, trained in ArcMap digitization techniques and led by volunteer project leader Daniel Gruber, performed the digitization work. Technical oversight of mapping using ArcMap, including provision of USGS-based mapping toolbars, was provided by Arizona Geological Survey (AZGS) research geologist Brian Gootee. The map digitization process identified and helped resolve a number of mapping questions. The citizen-scientist team spent 900 hours on training, digitization, quality checking, and project coordination with support and review by Skotnicki and Gootee. The resulting digital map has approximately 3000 polygons, 3000 points, and 86 map units with complete metadata and unit descriptions. The finished map is available online through AZGS and can be accessed in the field on mobile devices. User location is shown on the map and metadata can be viewed with a tap. The citizen scientist map digitization team has made this important geologic information available to the public and accessible to other researchers quickly and efficiently.

Short communication: Prevalence of digital dermatitis in Canadian dairy cattle classified as high, average, or low antibody- and cell-mediated immune responders.

PubMed

Cartwright, S L; Malchiodi, F; Thompson-Crispi, K; Miglior, F; Mallard, B A

2017-10-01

Lameness is a major animal welfare issue affecting Canadian dairy producers, and it can lead to production, reproduction, and health problems in dairy cattle herds. Although several different lesions affect dairy cattle hooves, studies show that digital dermatitis is the most common lesion identified in Canadian dairy herds. It has also been shown that dairy cattle classified as having high immune response (IR) have lower incidence of disease compared with those animals with average and low IR; therefore, it has been hypothesized that IR plays a role in preventing infectious hoof lesions. The objective of this study was to compare the prevalence of digital dermatitis in Canadian dairy cattle that were classified for antibody-mediated (AMIR) and cell-mediated (CMIR) immune response. Cattle (n = 329) from 5 commercial dairy farms in Ontario were evaluated for IR using a patented test protocol that captures both AMIR and CMIR. Individuals were classified as high, average, or low responders based on standardized residuals for AMIR and CMIR. Residuals were calculated using a general linear model that included the effects of herd, parity, stage of lactation, and stage of pregnancy. Hoof health data were collected from 2011 to 2013 by the farm's hoof trimmer using Hoof Supervisor software (KS Dairy Consulting Inc., Dresser, WI). All trim events were included for each animal, and lesions were assessed as a binary trait at each trim event. Hoof health data were analyzed using a mixed model that included the effects of herd, stage of lactation (at trim date), parity (at trim date), IR category (high, average, and low), and the random effect of animal. All data were presented as prevalence within IR category. Results showed that cows with high AMIR had significantly lower prevalence of digital dermatitis than cattle with average and low AMIR. No significant difference in prevalence of digital dermatitis was observed between high, average, and low CMIR cows. These results indicate that having more robust AMIR is associated with lower prevalence of digital dermatitis hoof lesions. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Detection system for high-resolution gamma radiation spectroscopy with neutron time-of-flight filtering

DOEpatents

Dioszegi, Istvan; Salwen, Cynthia; Vanier, Peter

2014-12-30

A .gamma.-radiation detection system that includes at least one semiconductor detector such as HPGe-Detector, a position-sensitive .alpha.-Detector, a TOF Controller, and a Digitizer/Integrator. The Digitizer/Integrator starts to process the energy signals of a .gamma.-radiation sent from the HPGe-Detector instantly when the HPGe-Detector detects the .gamma.-radiation. Subsequently, it is determined whether a coincidence exists between the .alpha.-particles and .gamma.-radiation signal, based on a determination of the time-of-flight of neutrons obtained from the .alpha.-Detector and the HPGe-Detector. If it is determined that the time-of-flight falls within a predetermined coincidence window, the Digitizer/Integrator is allowed to continue and complete the energy signal processing. If, however, there is no coincidence, the Digitizer/Integrator is instructed to be clear and reset its operation instantly.

Population health-based approaches to utilizing digital technology: a strategy for equity.

PubMed

Graham, Garth N; Ostrowski, MaryLynn; Sabina, Alyse B

2016-11-01

Health care disparities and high chronic disease rates burden many communities and disproportionally impact racial/ethnic populations in the United States. These disparities vary geographically, increase health care expenses, and result in shortened lifespans. Digital technologies may be one tool for addressing health disparities and improving population health by increasing individuals' access to health information-especially as most low-income U.S. residents gain access to smartphones. The Aetna Foundation partners with organizations to use digital technologies, including mobile applications, data collection, and related platforms, for learning and sharing. Projects range from the broad-childhood education, lifestyle modification, health IT training, and nutrition education, to the specific-local healthy foods, stroke rehabilitation, and collection of city-level data. We describe our approaches to grantmaking and discuss lessons learned and their implications. When combined with sound policy strategies, emerging, scalable, digital technologies will likely become powerful allies for improving health and reducing health disparities.

Digital phonocardiographic experiments and signal processing in multidisciplinary fields of university education

NASA Astrophysics Data System (ADS)

Nagy, Tamás; Vadai, Gergely; Gingl, Zoltán

2017-09-01

Modern measurement of physical signals is based on the use of sensors, electronic signal conditioning, analog-to-digital conversion and digital signal processing carried out by dedicated software. The same signal chain is used in many devices such as home appliances, automotive electronics, medical instruments, and smartphones. Teaching the theoretical, experimental, and signal processing background must be an essential part of improving the standard of higher education, and it fits well to the increasingly multidisciplinary nature of physics and engineering too. In this paper, we show how digital phonocardiography can be used in university education as a universal, highly scalable, exciting, and inspiring laboratory practice and as a demonstration at various levels and complexity. We have developed open-source software templates in modern programming languages to support immediate use and to serve as a basis of further modifications using personal computers, tablets, and smartphones.

Usage of a Digital Health Workplace Intervention Based on Socioeconomic Environment and Race: Retrospective Secondary Cross-Sectional Study.

PubMed

Senecal, Conor; Widmer, R Jay; Bailey, Kent; Lerman, Lilach O; Lerman, Amir

2018-04-23

Digital health tools have been associated with improvement of cardiovascular disease (CVD) risk factors and outcomes; however, the differential use of these technologies among various ethnic and economic classes is not well known. To identify the effect of socioeconomic environment on usage of a digital health intervention. A retrospective secondary cross-sectional analysis of a workplace digital health tool use, in association with a change in intermediate markers of CVD, was undertaken over the course of one year in 26,188 participants in a work health program across 81 organizations in 42 American states between 2011 and 2014. Baseline demographic data for participants included age, sex, race, home zip code, weight, height, blood pressure, glucose, lipids, and hemoglobin A 1c . Follow-up data was then obtained in 90-day increments for up to one year. Using publicly available data from the American Community Survey, we obtained the median income for each zip code as a marker for socioeconomic status via median household income. Digital health intervention usage was analyzed based on socioeconomic status as well as age, gender, and race. The cohort was found to represent a wide sample of socioeconomic environments from a median income of US $11,000 to $171,000. As a whole, doubling of income was associated with 7.6% increase in log-in frequency. However, there were marked differences between races. Black participants showed a 40.5% increase and Hispanic participants showed a 57.8% increase in use with a doubling of income, compared to 3% for Caucasian participants. The current study demonstrated that socioeconomic data confirms no relevant relationship between socioeconomic environment and digital health intervention usage for Caucasian users. However, a strong relationship is present for black and Hispanic users. Thus, socioeconomic environment plays a prominent role only in minority groups that represent a high-risk group for CVD. This finding identifies a need for digital health apps that are effective in these high-risk groups. ©Conor Senecal, R Jay Widmer, Kent Bailey, Lilach O Lerman, Amir Lerman. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 23.04.2018.

Digital photography and 3D MRI-based multimodal imaging for individualized planning of resective neocortical epilepsy surgery.

PubMed

Wellmer, Jörg; von Oertzen, Joachim; Schaller, Carlo; Urbach, Horst; König, Roy; Widman, Guido; Van Roost, Dirk; Elger, Christian E

2002-12-01

Invasive presurgical work up of pharmacoresistant epilepsies presumes integration of multiple diagnostic modalities into a comprehensive picture of seizure onset and eloquent brain areas. During resection, reliable transfer of evaluation results to the patient's individual anatomy must be made. We investigated the value of digital photography-based grid localization in combination with preoperative three-dimensional (3D) magnetic resonance imaging (MRI) for clinical routine. Digital photographs of the exposed cortex were taken before and after grid placement. Location of electrode contacts on the cortex was identified and schematically indicated on native cortex prints. Accordingly, transfer of contact positions to a 3D MRI brain-surface rendering was carried out manually by using the rendering software. Results of the electrophysiologic evaluation were transferred to either electrode contact reproduction and co-registered with imaging-based techniques such as single-photon emission computed tomography (SPECT), positron emission tomography (PET), and functional MRI (fMRI). Digital photography allows precise and highly realistic documentation of electrode contact positions on the individual neocortical surface. Lesions underneath grids can be highlighted by semitransparent MRI surface rendering, and lobar boundaries can be identified. Because of integrating electrode contact positions into the postprocessed 3D MRI data set, imaging-based techniques can be codisplayed with the results of the electrophysiologic evaluation. Comparison with CT/MRI co-registration showed good accuracy of the method. However, grids not sewn to the dura at implantation can become subject to significant displacement. Digital photography in combination with preimplantation 3D MRI allows the generation of reliable tailored resection plans in neocortical epilepsy surgery. The method enhances surgical safety and confidence.

Optimal micro-mirror tilt angle and sync mark design for digital micro-mirror device based collinear holographic data storage system.

PubMed

Liu, Jinpeng; Horimai, Hideyoshi; Lin, Xiao; Liu, Jinyan; Huang, Yong; Tan, Xiaodi

2017-06-01

The collinear holographic data storage system (CHDSS) is a very promising storage system due to its large storage capacities and high transfer rates in the era of big data. The digital micro-mirror device (DMD) as a spatial light modulator is the key device of the CHDSS due to its high speed, high precision, and broadband working range. To improve the system stability and performance, an optimal micro-mirror tilt angle was theoretically calculated and experimentally confirmed by analyzing the relationship between the tilt angle of the micro-mirror on the DMD and the power profiles of diffraction patterns of the DMD at the Fourier plane. In addition, we proposed a novel chess board sync mark design in the data page to reduce the system bit error rate in circumstances of reduced aperture required to decrease noise and median exposure amount. It will provide practical guidance for future DMD based CHDSS development.

DESDynI Quad First Stage Processor - A Four Channel Digitizer and Digital Beam Forming Processor

NASA Technical Reports Server (NTRS)

Chuang, Chung-Lun; Shaffer, Scott; Smythe, Robert; Niamsuwan, Noppasin; Li, Samuel; Liao, Eric; Lim, Chester; Morfopolous, Arin; Veilleux, Louise

2013-01-01

The proposed Deformation, Eco-Systems, and Dynamics of Ice Radar (DESDynI-R) L-band SAR instrument employs multiple digital channels to optimize resolution while keeping a large swath on a single pass. High-speed digitization with very fine synchronization and digital beam forming are necessary in order to facilitate this new technique. The Quad First Stage Processor (qFSP) was developed to achieve both the processing performance as well as the digitizing fidelity in order to accomplish this sweeping SAR technique. The qFSP utilizes high precision and high-speed analog to digital converters (ADCs), each with a finely adjustable clock distribution network to digitize the channels at the fidelity necessary to allow for digital beam forming. The Xilinx produced FX130T Virtex 5 part handles the processing to digitally calibrate each channel as well as filter and beam form the receive signals. Demonstrating the digital processing required for digital beam forming and digital calibration is instrumental to the viability of the proposed DESDynI instrument. The qFSP development brings this implementation to Technology Readiness Level (TRL) 6. This paper will detail the design and development of the prototype qFSP as well as the preliminary results from hardware tests.

Digital core based transmitted ultrasonic wave simulation and velocity accuracy analysis

NASA Astrophysics Data System (ADS)

Zhu, Wei; Shan, Rui

2016-06-01

Transmitted ultrasonic wave simulation (TUWS) in a digital core is one of the important elements of digital rock physics and is used to study wave propagation in porous cores and calculate equivalent velocity. When simulating wave propagates in a 3D digital core, two additional layers are attached to its two surfaces vertical to the wave-direction and one planar wave source and two receiver-arrays are properly installed. After source excitation, the two receivers then record incident and transmitted waves of the digital rock. Wave propagating velocity, which is the velocity of the digital core, is computed by the picked peak-time difference between the two recorded waves. To evaluate the accuracy of TUWS, a digital core is fully saturated with gas, oil, and water to calculate the corresponding velocities. The velocities increase with decreasing wave frequencies in the simulation frequency band, and this is considered to be the result of scattering. When the pore fluids are varied from gas to oil and finally to water, the velocity-variation characteristics between the different frequencies are similar, thereby approximately following the variation law of velocities obtained from linear elastic statics simulation (LESS), although their absolute values are different. However, LESS has been widely used. The results of this paper show that the transmission ultrasonic simulation has high relative precision.

Dual-energy in mammography: feasibility study

NASA Astrophysics Data System (ADS)

Jafroudi, Hamid; Lo, Shih-Chung B.; Li, Huai; Steller Artz, Dorothy E.; Freedman, Matthew T.; Mun, Seong K.

1996-04-01

The purpose of this work is to examine the feasibility of dual-energy techniques to enhance the detection of microcalcifications in digital mammography. The digital mammography system used in this study consists of two different mammography systems; one is the conventional mammography system with molybdenum target and Mo filtration and the other is the clinical version of a low dose x-ray system with tungsten target and aluminum filtration. The low dose system is optimized for screen-film mammography with a highly efficient scatter rejection device built by Fischer Imaging Systems for evaluation at NIH. The system was designed by the University of Southern California based on multiparameter optimization techniques. Prototypes of this system have been constructed and evaluated at the Center for Devices and Radiological Health. The digital radiography system is based on the Fuji 9000 computed radiography (CR) system which uses a storage phosphor imaging plate as the receptor. High resolution plates (HR-V) are used in this study. Dual-energy is one technique to reduce the structured noise associated with the complexity of the background of normal anatomy surrounding a lesion. This can be done by taking the advantage of the x-ray attenuation characteristics of two different structures such as soft tissue and bone in chest radiography. We have applied this technique to the detection of microcalcifications in mammography. The overall system performance based on this technique is evaluated. Results presented are based on the evaluation of phantom images.

Intermediate frequency band digitized high dynamic range radiometer system for plasma diagnostics and real-time Tokamak control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bongers, W. A.; Beveren, V. van; Westerhof, E.

2011-06-15

An intermediate frequency (IF) band digitizing radiometer system in the 100-200 GHz frequency range has been developed for Tokamak diagnostics and control, and other fields of research which require a high flexibility in frequency resolution combined with a large bandwidth and the retrieval of the full wave information of the mm-wave signals under investigation. The system is based on directly digitizing the IF band after down conversion. The enabling technology consists of a fast multi-giga sample analog to digital converter that has recently become available. Field programmable gate arrays (FPGA) are implemented to accomplish versatile real-time data analysis. A prototypemore » system has been developed and tested and its performance has been compared with conventional electron cyclotron emission (ECE) spectrometer systems. On the TEXTOR Tokamak a proof of principle shows that ECE, together with high power injected and scattered radiation, becomes amenable to measurement by this device. In particular, its capability to measure the phase of coherent signals in the spectrum offers important advantages in diagnostics and control. One case developed in detail employs the FPGA in real-time fast Fourier transform (FFT) and additional signal processing. The major benefit of such a FFT-based system is the real-time trade-off that can be made between frequency and time resolution. For ECE diagnostics this corresponds to a flexible spatial resolution in the plasma, with potential application in smart sensing of plasma instabilities such as the neoclassical tearing mode (NTM) and sawtooth instabilities. The flexible resolution would allow for the measurement of the full mode content of plasma instabilities contained within the system bandwidth.« less

Future of printing: changes and challenges, technologies and markets

NASA Astrophysics Data System (ADS)

Kipphan, Helmut

1998-01-01

Digitalization within the graphic arts industry is described and it is explained how it is improving and changing the print production strategies and which new kinds of print production systems are developed or can be expected. The relationship of printed media and electronic media is analyzed and a positioning for the next century is given. The state of the art of conventional printing technologies, especially using direct imagine techniques, and their position within the digital workflow are shortly described. Non-impact printing multicolor printing systems are explained, based on general design criteria and linked to existing and newly announced equipment. The use of high-tech components for building up successful systems with high reliability, high quality and low production costs is included with some examples. Digital printing systems open many opportunities in print production: distributed printing, personalization, print and book on demand are explained as examples. The overview of the several printing technologies and their positioning regarding quality and productivity leads to the scenario about the important position of printed media, also in the distant future.

Digital Imprinting of RNA Recognition and Processing on a Self-Assembled Nucleic Acid Matrix

NASA Astrophysics Data System (ADS)

Redhu, Shiv K.; Castronovo, Matteo; Nicholson, Allen W.

2013-08-01

The accelerating progress of research in nanomedicine and nanobiotechnology has included initiatives to develop highly-sensitive, high-throughput methods to detect biomarkers at the single-cell level. Current sensing approaches, however, typically involve integrative instrumentation that necessarily must balance sensitivity with rapidity in optimizing biomarker detection quality. We show here that laterally-confined, self-assembled monolayers of a short, double-stranded(ds)[RNA-DNA] chimera enable permanent digital detection of dsRNA-specific inputs. The action of ribonuclease III and the binding of an inactive, dsRNA-binding mutant can be permanently recorded by the input-responsive action of a restriction endonuclease that cleaves an ancillary reporter site within the dsDNA segment. The resulting irreversible height change of the arrayed ds[RNA-DNA], as measured by atomic force microscopy, provides a distinct digital output for each dsRNA-specific input. These findings provide the basis for developing imprinting-based bio-nanosensors, and reveal the versatility of AFM as a tool for characterizing the behaviour of highly-crowded biomolecules at the nanoscale.

Digital Microfluidics Assisted Sealing of Individual Magnetic Particles in Femtoliter-Sized Reaction Wells for Single-Molecule Detection.

PubMed

Decrop, Deborah; Ruiz, Elena Pérez; Kumar, Phalguni Tewari; Tripodi, Lisa; Kokalj, Tadej; Lammertyn, Jeroen

2017-01-01

Digital microfluidics has emerged in the last years as a promising liquid handling technology for a variety of applications. Here, we describe in detail how to build up an electrowetting-on-dielectric-based digital microfluidic chip with unique advantages for performing single-molecule detection. We illustrate how superparamagnetic particles can be printed with very high loading efficiency (over 98 %) and single-particle resolution in the microwell array patterned in the Teflon-AF ® surface of the grounding plate of the chip. Finally, the potential of the device for its application to single-molecule detection is demonstrated by the ultrasensitive detection of the biotinylated enzyme β-Galactosidase captured on streptavidin-coated particles in the described platform.

ESA personal communications and digital audio broadcasting systems based on non-geostationary satellites

NASA Technical Reports Server (NTRS)

Logalbo, P.; Benedicto, J.; Viola, R.

1993-01-01

Personal Communications and Digital Audio Broadcasting are two new services that the European Space Agency (ESA) is investigating for future European and Global Mobile Satellite systems. ESA is active in promoting these services in their various mission options including non-geostationary and geostationary satellite systems. A Medium Altitude Global Satellite System (MAGSS) for global personal communications at L and S-band, and a Multiregional Highly inclined Elliptical Orbit (M-HEO) system for multiregional digital audio broadcasting at L-band are described. Both systems are being investigated by ESA in the context of future programs, such as Archimedes, which are intended to demonstrate the new services and to develop the technology for future non-geostationary mobile communication and broadcasting satellites.

Background feature descriptor for offline handwritten numeral recognition

NASA Astrophysics Data System (ADS)

Ming, Delie; Wang, Hao; Tian, Tian; Jie, Feiran; Lei, Bo

2011-11-01

This paper puts forward an offline handwritten numeral recognition method based on background structural descriptor (sixteen-value numerical background expression). Through encoding the background pixels in the image according to a certain rule, 16 different eigenvalues were generated, which reflected the background condition of every digit, then reflected the structural features of the digits. Through pattern language description of images by these features, automatic segmentation of overlapping digits and numeral recognition can be realized. This method is characterized by great deformation resistant ability, high recognition speed and easy realization. Finally, the experimental results and conclusions are presented. The experimental results of recognizing datasets from various practical application fields reflect that with this method, a good recognition effect can be achieved.

3D printing in social education: Eki-Fab and student PBL

NASA Astrophysics Data System (ADS)

Makino, Masato; Saito, Azusa; Kodama, Mai; Takamatsu, Kyuuichiro; Tamate, Hideaki; Sakai, Kazuyuki; Wada, Masato; Khosla, Ajit; Kawakami, Masaru; Furukawa, Hidemitsu

2017-04-01

Additive manufacturing or 3D printer is one of the most innovative material processing methods. We are considering that human resources for 3D printing would be needed in the future. To educate the abilities of the digital fabrication, we have the public digital fabrication space "Eki-Fab" for junior and high school students and Project Based Learning (PBL) class for undergraduate students. Eki-Fab is held on every Saturday at the Yonezawa train station. In the "Eki-Fab", anybody can study the utilizing of 3D printer and modeling technics under the instruction of staff in Yamagata University. In the PBL class, we have the class every Thursday. The students get the techniques of the digital fabrication through the PBL.

Digital video steganalysis exploiting collusion sensitivity

NASA Astrophysics Data System (ADS)

Budhia, Udit; Kundur, Deepa

2004-09-01

In this paper we present an effective steganalyis technique for digital video sequences based on the collusion attack. Steganalysis is the process of detecting with a high probability and low complexity the presence of covert data in multimedia. Existing algorithms for steganalysis target detecting covert information in still images. When applied directly to video sequences these approaches are suboptimal. In this paper, we present a method that overcomes this limitation by using redundant information present in the temporal domain to detect covert messages in the form of Gaussian watermarks. Our gains are achieved by exploiting the collusion attack that has recently been studied in the field of digital video watermarking, and more sophisticated pattern recognition tools. Applications of our scheme include cybersecurity and cyberforensics.

Analog synthetic biology.

PubMed

Sarpeshkar, R

2014-03-28

We analyse the pros and cons of analog versus digital computation in living cells. Our analysis is based on fundamental laws of noise in gene and protein expression, which set limits on the energy, time, space, molecular count and part-count resources needed to compute at a given level of precision. We conclude that analog computation is significantly more efficient in its use of resources than deterministic digital computation even at relatively high levels of precision in the cell. Based on this analysis, we conclude that synthetic biology must use analog, collective analog, probabilistic and hybrid analog-digital computational approaches; otherwise, even relatively simple synthetic computations in cells such as addition will exceed energy and molecular-count budgets. We present schematics for efficiently representing analog DNA-protein computation in cells. Analog electronic flow in subthreshold transistors and analog molecular flux in chemical reactions obey Boltzmann exponential laws of thermodynamics and are described by astoundingly similar logarithmic electrochemical potentials. Therefore, cytomorphic circuits can help to map circuit designs between electronic and biochemical domains. We review recent work that uses positive-feedback linearization circuits to architect wide-dynamic-range logarithmic analog computation in Escherichia coli using three transcription factors, nearly two orders of magnitude more efficient in parts than prior digital implementations.

Analog synthetic biology

PubMed Central

Sarpeshkar, R.

2014-01-01

We analyse the pros and cons of analog versus digital computation in living cells. Our analysis is based on fundamental laws of noise in gene and protein expression, which set limits on the energy, time, space, molecular count and part-count resources needed to compute at a given level of precision. We conclude that analog computation is significantly more efficient in its use of resources than deterministic digital computation even at relatively high levels of precision in the cell. Based on this analysis, we conclude that synthetic biology must use analog, collective analog, probabilistic and hybrid analog–digital computational approaches; otherwise, even relatively simple synthetic computations in cells such as addition will exceed energy and molecular-count budgets. We present schematics for efficiently representing analog DNA–protein computation in cells. Analog electronic flow in subthreshold transistors and analog molecular flux in chemical reactions obey Boltzmann exponential laws of thermodynamics and are described by astoundingly similar logarithmic electrochemical potentials. Therefore, cytomorphic circuits can help to map circuit designs between electronic and biochemical domains. We review recent work that uses positive-feedback linearization circuits to architect wide-dynamic-range logarithmic analog computation in Escherichia coli using three transcription factors, nearly two orders of magnitude more efficient in parts than prior digital implementations. PMID:24567476

UAV-based photogrammetry combination of the elevational outcrop and digital surface models: an example of Sanyi active fault in western Taiwan

NASA Astrophysics Data System (ADS)

Hsieh, Cheng-En; Huang, Wen-Jeng; Chang, Ping-Yu; Lo, Wei

2016-04-01

An unmanned aerial vehicle (UAV) with a digital camera is an efficient tool for geologists to investigate structure patterns in the field. By setting ground control points (GCPs), UAV-based photogrammetry provides high-quality and quantitative results such as a digital surface model (DSM) and orthomosaic and elevational images. We combine the elevational outcrop 3D model and a digital surface model together to analyze the structural characteristics of Sanyi active fault in Houli-Fengyuan area, western Taiwan. Furthermore, we collect resistivity survey profiles and drilling core data in the Fengyuan District in order to build the subsurface fault geometry. The ground sample distance (GSD) of an elevational outcrop 3D model is 3.64 cm/pixel in this study. Our preliminary result shows that 5 fault branches are distributed 500 meters wide on the elevational outcrop and the width of Sanyi fault zone is likely much great than this value. Together with our field observations, we propose a structural evolution model to demonstrate how the 5 fault branches developed. The resistivity survey profiles show that Holocene gravel was disturbed by the Sanyi fault in Fengyuan area.

New satellite mission with old data: Rescuing a unique data set

NASA Astrophysics Data System (ADS)

Benson, Robert F.; Bilitza, Dieter

2009-02-01

We review efforts to save a unique data set and scientific results based on the rescued data. The goal of the project was to produce Alouette 2, ISIS 1, and ISIS 2 digital topside ionograms from selected original seven-track analog telemetry tapes. This project was initiated to preserve a significant portion of 60 satellite years of analog data, collected between 1962 and 1990, in digital form before the tapes were discarded. More than 1/2 million digital topside ionograms are now available for downloading at http://nssdcftp.gsfc.nasa.gov and for browsing and plotting at http://cdaweb.gsfc.nasa.gov. We illustrate data products, discuss analysis programs, review scientific results based on the digital data, and recognize those who made the project possible. The scientific results include evidence of extremely low altitude ionospheric peak densities at high latitudes, improved and new ionospheric models including one connecting the F2 topside ionosphere and the plasmasphere, transionospheric HF propagation investigations, and new interpretations of sounder-stimulated plasma emissions that have challenged theorists for decades. The homepage for the ISIS project is at http://nssdc.gsfc.nasa.gov/space/isis/isis-status.html.

Spatial imaging in color and HDR: prometheus unchained

NASA Astrophysics Data System (ADS)

McCann, John J.

2013-03-01

The Human Vision and Electronic Imaging Conferences (HVEI) at the IS and T/SPIE Electronic Imaging meetings have brought together research in the fundamentals of both vision and digital technology. This conference has incorporated many color disciplines that have contributed to the theory and practice of today's imaging: color constancy, models of vision, digital output, high-dynamic-range imaging, and the understanding of perceptual mechanisms. Before digital imaging, silver halide color was a pixel-based mechanism. Color films are closely tied to colorimetry, the science of matching pixels in a black surround. The quanta catch of the sensitized silver salts determines the amount of colored dyes in the final print. The rapid expansion of digital imaging over the past 25 years has eliminated the limitations of using small local regions in forming images. Spatial interactions can now generate images more like vision. Since the 1950's, neurophysiology has shown that post-receptor neural processing is based on spatial interactions. These results reinforced the findings of 19th century experimental psychology. This paper reviews the role of HVEI in color, emphasizing the interaction of research on vision and the new algorithms and processes made possible by electronic imaging.

Smart Antenna UKM Testbed for Digital Beamforming System

NASA Astrophysics Data System (ADS)

Islam, Mohammad Tariqul; Misran, Norbahiah; Yatim, Baharudin

2009-12-01

A new design of smart antenna testbed developed at UKM for digital beamforming purpose is proposed. The smart antenna UKM testbed developed based on modular design employing two novel designs of L-probe fed inverted hybrid E-H (LIEH) array antenna and software reconfigurable digital beamforming system (DBS). The antenna is developed based on using the novel LIEH microstrip patch element design arranged into [InlineEquation not available: see fulltext.] uniform linear array antenna. An interface board is designed to interface to the ADC board with the RF front-end receiver. The modular concept of the system provides the capability to test the antenna hardware, beamforming unit, and beamforming algorithm in an independent manner, thus allowing the smart antenna system to be developed and tested in parallel, hence reduces the design time. The DBS was developed using a high-performance [InlineEquation not available: see fulltext.] floating-point DSP board and a 4-channel RF front-end receiver developed in-house. An interface board is designed to interface to the ADC board with the RF front-end receiver. A four-element receiving array testbed at 1.88-2.22 GHz frequency is constructed, and digital beamforming on this testbed is successfully demonstrated.

A precise time synchronization method for 5G based on radio-over-fiber network with SDN controller

NASA Astrophysics Data System (ADS)

He, Linkuan; Wei, Baoguo; Yang, Hui; Yu, Ao; Wang, Zhengyong; Zhang, Jie

2018-02-01

There is an increasing demand on accurate time synchronization with the growing bandwidth of network service for 5G. In 5G network, it's necessary for base station to achieve accurate time synchronization to guarantee the quality of communication. In order to keep accuracy time for 5G network, we propose a time synchronization system for satellite ground station based on radio-over-fiber network (RoFN) with software defined optical network (SDON) controller. The advantage of this method is to improve the accuracy of time synchronization of ground station. The IEEE 1588 time synchronization protocol can solve the problems of high cost and lack of precision. However, in the process of time synchronization, distortion exists during the transmission of digital time signal. RoF uses analog optical transmission links and therefore analog transmission can be implemented among ground stations instead of digital transmission, which means distortion and bandwidth waste in the process of digital synchronization can be avoided. Additionally, the thought of SDN, software defined network, can optimize RoFN with centralized control and simplifying base station. Related simulation had been carried out to prove its superiority.

The modulation and demodulation module of a high resolution MOEMS accelerometer

NASA Astrophysics Data System (ADS)

Jiao, Xufen; Bai, Jian; Lu, Qianbo; Lou, Shuqi

2016-02-01

A MOEMS accelerometer with high precision based on grating interferometer is demonstrated in this paper. In order to increase the signal-to-noise ratio (SNR) and accuracy, a specific modulator and an orthogonal phase-lock demodulator are proposed. Phase modulation is introduced to this accelerometer by applying a sinusoidal signal to a piezoelectric translator (PZT) amounted to the accelerometer. Phase demodulation module consists of a circuit design and a digital design. In the circuit design, the modulated light intensity signal is converted to a voltage signal and processed. In the digital part, the demodulator is mainly composed of a Band Pass Filter, two Phase-Sensitive Detectors, a phase shifter, and two Low Pass Filters based on virtual instrument. Simulation results indicate that this approach can decrease the noise greatly, and the SNR of this demodulator is 50dB and the relative error is less than 4%.

Digital Topographic Mapping in Urban Obstructed Environment Based on Multi-GNSS Network RTK Technology

NASA Astrophysics Data System (ADS)

Guo, Qiuying; Zhao, Tonglong; Zhang, Chao; Wu, Xuxiang

2017-10-01

Digital topographic mapping experiments were carried out based on network RTK technology using GPS/BEIDOU/GLONASS multi-constellation compatible GNSS receivers in urban obstructed environment. Operation scheme and technique flow were discussed. Experimental results show that the horizontal position and elevation of the points measured by RTK can reach 2cm and 3cm precision level respectively in open environment. RTK initialization time needs about 3-5s. While in obstructed environment, such as high building and tree shanding, the RTK initialization time needs about dozens of seconds or tens of seconds, and sometimes floating solutions or even differential solutions were obtained. The impact of dense and tall building on RTK measurement is more seriously. It is more likely to get RTK fixed solution in the south side of high building than the north side of the building.

ICE: A Scalable, Low-Cost FPGA-Based Telescope Signal Processing and Networking System

NASA Astrophysics Data System (ADS)

Bandura, K.; Bender, A. N.; Cliche, J. F.; de Haan, T.; Dobbs, M. A.; Gilbert, A. J.; Griffin, S.; Hsyu, G.; Ittah, D.; Parra, J. Mena; Montgomery, J.; Pinsonneault-Marotte, T.; Siegel, S.; Smecher, G.; Tang, Q. Y.; Vanderlinde, K.; Whitehorn, N.

2016-03-01

We present an overview of the ‘ICE’ hardware and software framework that implements large arrays of interconnected field-programmable gate array (FPGA)-based data acquisition, signal processing and networking nodes economically. The system was conceived for application to radio, millimeter and sub-millimeter telescope readout systems that have requirements beyond typical off-the-shelf processing systems, such as careful control of interference signals produced by the digital electronics, and clocking of all elements in the system from a single precise observatory-derived oscillator. A new generation of telescopes operating at these frequency bands and designed with a vastly increased emphasis on digital signal processing to support their detector multiplexing technology or high-bandwidth correlators — data rates exceeding a terabyte per second — are becoming common. The ICE system is built around a custom FPGA motherboard that makes use of an Xilinx Kintex-7 FPGA and ARM-based co-processor. The system is specialized for specific applications through software, firmware and custom mezzanine daughter boards that interface to the FPGA through the industry-standard FPGA mezzanine card (FMC) specifications. For high density applications, the motherboards are packaged in 16-slot crates with ICE backplanes that implement a low-cost passive full-mesh network between the motherboards in a crate, allow high bandwidth interconnection between crates and enable data offload to a computer cluster. A Python-based control software library automatically detects and operates the hardware in the array. Examples of specific telescope applications of the ICE framework are presented, namely the frequency-multiplexed bolometer readout systems used for the South Pole Telescope (SPT) and Simons Array and the digitizer, F-engine, and networking engine for the Canadian Hydrogen Intensity Mapping Experiment (CHIME) and Hydrogen Intensity and Real-time Analysis eXperiment (HIRAX) radio interferometers.

Field-Deployable Acoustic Digital Systems for Noise Measurement

NASA Technical Reports Server (NTRS)

Shams, Qamar A.; Wright, Kenneth D.; Lunsford, Charles B.; Smith, Charlie D.

2000-01-01

Langley Research Center (LaRC) has for years been a leader in field acoustic array measurement technique. Two field-deployable digital measurement systems have been developed to support acoustic research programs at LaRC. For several years, LaRC has used the Digital Acoustic Measurement System (DAMS) for measuring the acoustic noise levels from rotorcraft and tiltrotor aircraft. Recently, a second system called Remote Acquisition and Storage System (RASS) was developed and deployed for the first time in the field along with DAMS system for the Community Noise Flight Test using the NASA LaRC-757 aircraft during April, 2000. The test was performed at Airborne Airport in Wilmington, OH to validate predicted noise reduction benefits from alternative operational procedures. The test matrix was composed of various combinations of altitude, cutback power, and aircraft weight. The DAMS digitizes the acoustic inputs at the microphone site and can be located up to 2000 feet from the van which houses the acquisition, storage and analysis equipment. Digitized data from up to 10 microphones is recorded on a Jaz disk and is analyzed post-test by microcomputer system. The RASS digitizes and stores acoustic inputs at the microphone site that can be located up to three miles from the base station and can compose a 3 mile by 3 mile array of microphones. 16-bit digitized data from the microphones is stored on removable Jaz disk and is transferred through a high speed array to a very large high speed permanent storage device. Up to 30 microphones can be utilized in the array. System control and monitoring is accomplished via Radio Frequency (RF) link. This paper will present a detailed description of both systems, along with acoustic data analysis from both systems.

A high resolution on-chip delay sensor with low supply-voltage sensitivity for high-performance electronic systems.

PubMed

Sheng, Duo; Lai, Hsiu-Fan; Chan, Sheng-Min; Hong, Min-Rong

2015-02-13

An all-digital on-chip delay sensor (OCDS) circuit with high delay-measurement resolution and low supply-voltage sensitivity for efficient detection and diagnosis in high-performance electronic system applications is presented. Based on the proposed delay measurement scheme, the quantization resolution of the proposed OCDS can be reduced to several picoseconds. Additionally, the proposed cascade-stage delay measurement circuit can enhance immunity to supply-voltage variations of the delay measurement resolution without extra self-biasing or calibration circuits. Simulation results show that the delay measurement resolution can be improved to 1.2 ps; the average delay resolution variation is 0.55% with supply-voltage variations of ±10%. Moreover, the proposed delay sensor can be implemented in an all-digital manner, making it very suitable for high-performance electronic system applications as well as system-level integration.

Hydrodynamics of a Digitized Adult Humpback Whale Flipper

NASA Astrophysics Data System (ADS)

Fassmann, Wesley N.; McDonald, Samuel J.; Thomson, Scott L.; Fish, Frank E.

2013-11-01

During feeding, humpback whales turn with a turn radius of up to 1 /6th of their length towards schools of fish enclosed by bubble nets. This high maneuverability requirement is facilitated by high aspect ratio flippers with leading edge tubercles that delay stall. Previous experimental and computational studies have used idealized models, such as airfoils with scalloped leading edges, to explore the influence of leading edge tubercles on boundary layer separation, vortex generation, and airfoil lift and drag characteristics. Owing to the substantial size of the flipper, no studies have been performed on a digitized adult humpback flipper with real geometry. In this study the hydrodynamics of a realistic humpback flipper model were explored. The model was developed by digitizing a sequence of 18 images circumscribing the suspended flipper of a beached humpback whale. A physical prototype was constructed based on the resulting 3D model, along with a complementary model with the tubercles removed. Experimentally-obtained measurements of lift and drag were used to study the influence of the tubercles. In the presentation, digitization and flow measurement methods are described, and the flow data and results are presented and discussed.

12-bit 32 channel 500 MS/s low-latency ADC for particle accelerators real-time control

NASA Astrophysics Data System (ADS)

Karnitski, Anton; Baranauskas, Dalius; Zelenin, Denis; Baranauskas, Gytis; Zhankevich, Alexander; Gill, Chris

2017-09-01

Particle beam control systems require real-time low latency digital feedback with high linearity and dynamic range. Densely packed electronic systems employ high performance multichannel digitizers causing excessive heat dissipation. Therefore, low power dissipation is another critical requirement for these digitizers. A described 12-bit 500 MS/s ADC employs a sub-ranging architecture based on a merged sample & hold circuit, a residue C-DAC and a shared 6-bit flash core ADC. The core ADC provides a sequential coarse and fine digitization featuring a latency of two clock cycles. The ADC is implemented in a 28 nm CMOS process and consumes 4 mW of power per channel from a 0.9 V supply (interfacing and peripheral circuits are excluded). Reduced power consumption and small on-chip area permits the implementation of 32 ADC channels on a 10.7 mm2 chip. The ADC includes a JESD204B standard compliant output data interface operated at the 7.5 Gbps/ch rate. To minimize the data interface related time latency, a special feature permitting to bypass the JESD204B interface is built in. DoE Phase I Award Number: DE-SC0017213.

Flight control systems development of highly maneuverable aircraft technology /HiMAT/ vehicle

NASA Technical Reports Server (NTRS)

Petersen, K. L.

1979-01-01

The highly maneuverable aircraft technology (HiMAT) program was conceived to demonstrate advanced technology concepts through scaled-aircraft flight tests using a remotely piloted technique. Closed-loop primary flight control is performed from a ground-based cockpit, utilizing a digital computer and up/down telemetry links. A backup flight control system for emergency operation resides in an onboard computer. The onboard systems are designed to provide fail-operational capabilities and utilize two microcomputers, dual uplink receiver/decoders, and redundant hydraulic actuation and power systems. This paper discusses the design and validation of the primary and backup digital flight control systems as well as the unique pilot and specialized systems interfaces.

Learning representation hierarchies by sharing visual features: a computational investigation of Persian character recognition with unsupervised deep learning.

PubMed

Sadeghi, Zahra; Testolin, Alberto

2017-08-01

In humans, efficient recognition of written symbols is thought to rely on a hierarchical processing system, where simple features are progressively combined into more abstract, high-level representations. Here, we present a computational model of Persian character recognition based on deep belief networks, where increasingly more complex visual features emerge in a completely unsupervised manner by fitting a hierarchical generative model to the sensory data. Crucially, high-level internal representations emerging from unsupervised deep learning can be easily read out by a linear classifier, achieving state-of-the-art recognition accuracy. Furthermore, we tested the hypothesis that handwritten digits and letters share many common visual features: A generative model that captures the statistical structure of the letters distribution should therefore also support the recognition of written digits. To this aim, deep networks trained on Persian letters were used to build high-level representations of Persian digits, which were indeed read out with high accuracy. Our simulations show that complex visual features, such as those mediating the identification of Persian symbols, can emerge from unsupervised learning in multilayered neural networks and can support knowledge transfer across related domains.

A 12-bit high-speed column-parallel two-step single-slope analog-to-digital converter (ADC) for CMOS image sensors.

PubMed

Lyu, Tao; Yao, Suying; Nie, Kaiming; Xu, Jiangtao

2014-11-17

A 12-bit high-speed column-parallel two-step single-slope (SS) analog-to-digital converter (ADC) for CMOS image sensors is proposed. The proposed ADC employs a single ramp voltage and multiple reference voltages, and the conversion is divided into coarse phase and fine phase to improve the conversion rate. An error calibration scheme is proposed to correct errors caused by offsets among the reference voltages. The digital-to-analog converter (DAC) used for the ramp generator is based on the split-capacitor array with an attenuation capacitor. Analysis of the DAC's linearity performance versus capacitor mismatch and parasitic capacitance is presented. A prototype 1024 × 32 Time Delay Integration (TDI) CMOS image sensor with the proposed ADC architecture has been fabricated in a standard 0.18 μm CMOS process. The proposed ADC has average power consumption of 128 μW and a conventional rate 6 times higher than the conventional SS ADC. A high-quality image, captured at the line rate of 15.5 k lines/s, shows that the proposed ADC is suitable for high-speed CMOS image sensors.

Analog Module Architecture for Space-Qualified Field-Programmable Mixed-Signal Arrays

NASA Technical Reports Server (NTRS)

Edwards, R. Timothy; Strohbehn, Kim; Jaskulek, Steven E.; Katz, Richard

1999-01-01

Spacecraft require all manner of both digital and analog circuits. Onboard digital systems are constructed almost exclusively from field-programmable gate array (FPGA) circuits providing numerous advantages over discrete design including high integration density, high reliability, fast turn-around design cycle time, lower mass, volume, and power consumption, and lower parts acquisition and flight qualification costs. Analog and mixed-signal circuits perform tasks ranging from housekeeping to signal conditioning and processing. These circuits are painstakingly designed and built using discrete components due to a lack of options for field-programmability. FPAA (Field-Programmable Analog Array) and FPMA (Field-Programmable Mixed-signal Array) parts exist but not in radiation-tolerant technology and not necessarily in an architecture optimal for the design of analog circuits for spaceflight applications. This paper outlines an architecture proposed for an FPAA fabricated in an existing commercial digital CMOS process used to make radiation-tolerant antifuse-based FPGA devices. The primary concerns are the impact of the technology and the overall array architecture on the flexibility of programming, the bandwidth available for high-speed analog circuits, and the accuracy of the components for high-performance applications.

Power budget enhancement in NG-EPON system employing novel twisted-PAM4

NASA Astrophysics Data System (ADS)

Li, Longsheng; Bi, Meihua; Fu, Yan; Miao, Xin; Zhu, Qingming; Hu, Weisheng

2018-03-01

In this paper, we firstly design a novel modulation format named Twisted-PAM4 (T-PAM4) for the high-speed NG-EPON and the PON-based digital fronthaul system. Compared to other high-order modulation formats like 4-ary pulse amplitude modulation (PAM4), T-PAM4 provides two independent sampling values in each symbol period and enables two-dimensional symbol decision, which significantly improves the receiver sensitivity and hence enlarges the system power budget. Based on this advantage, six types of T-PAM4 are experimentally demonstrated in 28-Gb/s/ λ NG-PON and 32-Gb/s/ λ PON-based digital fronthaul system. The experimental results show that, compared to the ordinary PAM4, the T-PAM4 can bring 5-dB and 4-dB extra power budget in NG-EPON and PON-based fronthaul system respectively. In addition, by experiment, it is also depicted that the T-PAM4 is remarkably robust to system nonlinearity, which would ease the linearity requirement on system components and hence reduce system cost.

Modified signed-digit arithmetic based on redundant bit representation.

PubMed

Huang, H; Itoh, M; Yatagai, T

1994-09-10

Fully parallel modified signed-digit arithmetic operations are realized based on redundant bit representation of the digits proposed. A new truth-table minimizing technique is presented based on redundant-bitrepresentation coding. It is shown that only 34 minterms are enough for implementing one-step modified signed-digit addition and subtraction with this new representation. Two optical implementation schemes, correlation and matrix multiplication, are described. Experimental demonstrations of the correlation architecture are presented. Both architectures use fixed minterm masks for arbitrary-length operands, taking full advantage of the parallelism of the modified signed-digit number system and optics.

Mesoscale landscape model of gypsy moth phenology

Treesearch

Joseph M. Russo; John G. W. Kelley; Andrew M. Liebhold

1991-01-01

A recently-developed high resolution climatological temperature data base was input into a gypsy moth phenology model. The high resolution data were created from a coupling of 30-year averages of station observations and digital elevation data. The resultant maximum and minimum temperatures have about a 1 km resolution which represents meteorologically the mesoscale....

Increasing Electrochemiluminescence Intensity of a Wireless Electrode Array Chip by Thousands of Times Using a Diode for Sensitive Visual Detection by a Digital Camera.

PubMed

Qi, Liming; Xia, Yong; Qi, Wenjing; Gao, Wenyue; Wu, Fengxia; Xu, Guobao

2016-01-19

Both a wireless electrochemiluminescence (ECL) electrode microarray chip and the dramatic increase in ECL by embedding a diode in an electromagnetic receiver coil have been first reported. The newly designed device consists of a chip and a transmitter. The chip has an electromagnetic receiver coil, a mini-diode, and a gold electrode array. The mini-diode can rectify alternating current into direct current and thus enhance ECL intensities by 18 thousand times, enabling a sensitive visual detection using common cameras or smart phones as low cost detectors. The detection limit of hydrogen peroxide using a digital camera is comparable to that using photomultiplier tube (PMT)-based detectors. Coupled with a PMT-based detector, the device can detect luminol with higher sensitivity with linear ranges from 10 nM to 1 mM. Because of the advantages including high sensitivity, high throughput, low cost, high portability, and simplicity, it is promising in point of care testing, drug screening, and high throughput analysis.

Digital micromirror device-based ultrafast pulse shaping for femtosecond laser.

PubMed

Gu, Chenglin; Zhang, Dapeng; Chang, Yina; Chen, Shih-Chi

2015-06-15

In this Letter, we present a new digital micromirror device (DMD)-based ultrafast pulse shaper, i.e., DUPS. To the best of our knowledge, the DUPS is the first binary pulse shaper that can modulate high repetition rate laser sources at up to a 32 kHz rate (limited by the DMD pattern rate). Since pulse modulation occurs in the frequency domain through reflective two-dimensional micromirror arrays, i.e., DMD, the DUPS is not only compact and low in cost, but also possesses a high damage threshold that is critical for high pulse energy laser applications. In this work, a grating pair was introduced in the DUPS to compensate the DMD induced dispersion. Double pulses were generated to validate the effectiveness of the DUPS and calibrate the system. Subsequently, we demonstrated arbitrary phase shaping capability by continuous tuning of group velocity dispersion (GVD) and modulation of half-spectrum shifted by π. The overall efficiency was measured to be 1.7%, while an efficiency of up to 5% can be expected when high efficiency gratings and properly coated DMDs are used.

Measuring the global information society - explaining digital inequality by economic level and education standard

NASA Astrophysics Data System (ADS)

Ünver, H.

2017-02-01

A main focus of this research paper is to investigate on the explanation of the ‘digital inequality’ or ‘digital divide’ by economic level and education standard of about 150 countries worldwide. Inequality regarding GDP per capita, literacy and the so-called UN Education Index seem to be important factors affecting ICT usage, in particular Internet penetration, mobile phone usage and also mobile Internet services. Empirical methods and (multivariate) regression analysis with linear and non-linear functions are useful methods to measure some crucial factors of a country or culture towards becoming information and knowledge based society. Overall, the study concludes that the convergence regarding ICT usage proceeds worldwide faster than the convergence in terms of economic wealth and education in general. The results based on a large data analysis show that the digital divide is declining over more than a decade between 2000 and 2013, since more people worldwide use mobile phones and the Internet. But a high digital inequality explained to a significant extent by the functional relation between technology penetration rates, education level and average income still exists. Furthermore it supports the actions of countries at UN/G20/OECD level for providing ICT access to all people for a more balanced world in context of sustainable development by postulating that policymakers need to promote comprehensive education worldwide by means of using ICT.

BAO Plate Archive Project: Digitization, Electronic Database and Research Programmes

NASA Astrophysics Data System (ADS)

Mickaelian, A. M.; Abrahamyan, H. V.; Andreasyan, H. R.; Azatyan, N. M.; Farmanyan, S. V.; Gigoyan, K. S.; Gyulzadyan, M. V.; Khachatryan, K. G.; Knyazyan, A. V.; Kostandyan, G. R.; Mikayelyan, G. A.; Nikoghosyan, E. H.; Paronyan, G. M.; Vardanyan, A. V.

2016-06-01

The most important part of the astronomical observational heritage are astronomical plate archives created on the basis of numerous observations at many observatories. Byurakan Astrophysical Observatory (BAO) plate archive consists of 37,000 photographic plates and films, obtained at 2.6m telescope, 1m and 0.5m Schmidt type and other smaller telescopes during 1947-1991. In 2002-2005, the famous Markarian Survey (also called First Byurakan Survey, FBS) 1874 plates were digitized and the Digitized FBS (DFBS) was created. New science projects have been conducted based on these low-dispersion spectroscopic material. A large project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage was started in 2015. A Science Program Board is created to evaluate the observing material, to investigate new possibilities and to propose new projects based on the combined usage of these observations together with other world databases. The Executing Team consists of 11 astronomers and 2 computer scientists and will use 2 EPSON Perfection V750 Pro scanners for the digitization, as well as Armenian Virtual Observatory (ArVO) database will be used to accommodate all new data. The project will run during 3 years in 2015-2017 and the final result will be an electronic database and online interactive sky map to be used for further research projects, mainly including high proper motion stars, variable objects and Solar System bodies.

Digital image measurement of specimen deformation based on CCD cameras and Image J software: an application to human pelvic biomechanics

NASA Astrophysics Data System (ADS)

Jia, Yongwei; Cheng, Liming; Yu, Guangrong; Lou, Yongjian; Yu, Yan; Chen, Bo; Ding, Zuquan

2008-03-01

A method of digital image measurement of specimen deformation based on CCD cameras and Image J software was developed. This method was used to measure the biomechanics behavior of human pelvis. Six cadaveric specimens from the third lumbar vertebra to the proximal 1/3 part of femur were tested. The specimens without any structural abnormalities were dissected of all soft tissue, sparing the hip joint capsules and the ligaments of the pelvic ring and floor. Markers with black dot on white background were affixed to the key regions of the pelvis. Axial loading from the proximal lumbar was applied by MTS in the gradient of 0N to 500N, which simulated the double feet standing stance. The anterior and lateral images of the specimen were obtained through two CCD cameras. Based on Image J software, digital image processing software, which can be freely downloaded from the National Institutes of Health, digital 8-bit images were processed. The procedure includes the recognition of digital marker, image invert, sub-pixel reconstruction, image segmentation, center of mass algorithm based on weighted average of pixel gray values. Vertical displacements of S1 (the first sacral vertebrae) in front view and micro-angular rotation of sacroiliac joint in lateral view were calculated according to the marker movement. The results of digital image measurement showed as following: marker image correlation before and after deformation was excellent. The average correlation coefficient was about 0.983. According to the 768 × 576 pixels image (pixel size 0.68mm × 0.68mm), the precision of the displacement detected in our experiment was about 0.018 pixels and the comparatively error could achieve 1.11\\perthou. The average vertical displacement of S1 of the pelvis was 0.8356+/-0.2830mm under vertical load of 500 Newtons and the average micro-angular rotation of sacroiliac joint in lateral view was 0.584+/-0.221°. The load-displacement curves obtained from our optical measure system matched the clinical results. Digital image measurement of specimen deformation based on CCD cameras and Image J software has good perspective for application in biomechanical research, which has the advantage of simple optical setup, no-contact, high precision, and no special requirement of test environment.

Tampered Region Localization of Digital Color Images Based on JPEG Compression Noise

NASA Astrophysics Data System (ADS)

Wang, Wei; Dong, Jing; Tan, Tieniu

With the availability of various digital image edit tools, seeing is no longer believing. In this paper, we focus on tampered region localization for image forensics. We propose an algorithm which can locate tampered region(s) in a lossless compressed tampered image when its unchanged region is output of JPEG decompressor. We find the tampered region and the unchanged region have different responses for JPEG compression. The tampered region has stronger high frequency quantization noise than the unchanged region. We employ PCA to separate different spatial frequencies quantization noises, i.e. low, medium and high frequency quantization noise, and extract high frequency quantization noise for tampered region localization. Post-processing is involved to get final localization result. The experimental results prove the effectiveness of our proposed method.

Extraction of Urban Trees from Integrated Airborne Based Digital Image and LIDAR Point Cloud Datasets - Initial Results

NASA Astrophysics Data System (ADS)

Dogon-yaro, M. A.; Kumar, P.; Rahman, A. Abdul; Buyuksalih, G.

2016-10-01

Timely and accurate acquisition of information on the condition and structural changes of urban trees serves as a tool for decision makers to better appreciate urban ecosystems and their numerous values which are critical to building up strategies for sustainable development. The conventional techniques used for extracting tree features include; ground surveying and interpretation of the aerial photography. However, these techniques are associated with some constraint, such as labour intensive field work, a lot of financial requirement, influences by weather condition and topographical covers which can be overcome by means of integrated airborne based LiDAR and very high resolution digital image datasets. This study presented a semi-automated approach for extracting urban trees from integrated airborne based LIDAR and multispectral digital image datasets over Istanbul city of Turkey. The above scheme includes detection and extraction of shadow free vegetation features based on spectral properties of digital images using shadow index and NDVI techniques and automated extraction of 3D information about vegetation features from the integrated processing of shadow free vegetation image and LiDAR point cloud datasets. The ability of the developed algorithms shows a promising result as an automated and cost effective approach to estimating and delineated 3D information of urban trees. The research also proved that integrated datasets is a suitable technology and a viable source of information for city managers to be used in urban trees management.

High Performance Proactive Digital Forensics

NASA Astrophysics Data System (ADS)

Alharbi, Soltan; Moa, Belaid; Weber-Jahnke, Jens; Traore, Issa

2012-10-01

With the increase in the number of digital crimes and in their sophistication, High Performance Computing (HPC) is becoming a must in Digital Forensics (DF). According to the FBI annual report, the size of data processed during the 2010 fiscal year reached 3,086 TB (compared to 2,334 TB in 2009) and the number of agencies that requested Regional Computer Forensics Laboratory assistance increasing from 689 in 2009 to 722 in 2010. Since most investigation tools are both I/O and CPU bound, the next-generation DF tools are required to be distributed and offer HPC capabilities. The need for HPC is even more evident in investigating crimes on clouds or when proactive DF analysis and on-site investigation, requiring semi-real time processing, are performed. Although overcoming the performance challenge is a major goal in DF, as far as we know, there is almost no research on HPC-DF except for few papers. As such, in this work, we extend our work on the need of a proactive system and present a high performance automated proactive digital forensic system. The most expensive phase of the system, namely proactive analysis and detection, uses a parallel extension of the iterative z algorithm. It also implements new parallel information-based outlier detection algorithms to proactively and forensically handle suspicious activities. To analyse a large number of targets and events and continuously do so (to capture the dynamics of the system), we rely on a multi-resolution approach to explore the digital forensic space. Data set from the Honeynet Forensic Challenge in 2001 is used to evaluate the system from DF and HPC perspectives.

A Patient-Centered Framework for Evaluating Digital Maturity of Health Services: A Systematic Review

PubMed Central

Callahan, Ryan; Darzi, Ara; Mayer, Erik

2016-01-01

Background Digital maturity is the extent to which digital technologies are used as enablers to deliver a high-quality health service. Extensive literature exists about how to assess the components of digital maturity, but it has not been used to design a comprehensive framework for evaluation. Consequently, the measurement systems that do exist are limited to evaluating digital programs within one service or care setting, meaning that digital maturity evaluation is not accounting for the needs of patients across their care pathways. Objective The objective of our study was to identify the best methods and metrics for evaluating digital maturity and to create a novel, evidence-based tool for evaluating digital maturity across patient care pathways. Methods We systematically reviewed the literature to find the best methods and metrics for evaluating digital maturity. We searched the PubMed database for all papers relevant to digital maturity evaluation. Papers were selected if they provided insight into how to appraise digital systems within the health service and if they indicated the factors that constitute or facilitate digital maturity. Papers were analyzed to identify methodology for evaluating digital maturity and indicators of digitally mature systems. We then used the resulting information about methodology to design an evaluation framework. Following that, the indicators of digital maturity were extracted and grouped into increasing levels of maturity and operationalized as metrics within the evaluation framework. Results We identified 28 papers as relevant to evaluating digital maturity, from which we derived 5 themes. The first theme concerned general evaluation methodology for constructing the framework (7 papers). The following 4 themes were the increasing levels of digital maturity: resources and ability (6 papers), usage (7 papers), interoperability (3 papers), and impact (5 papers). The framework includes metrics for each of these levels at each stage of the typical patient care pathway. Conclusions The framework uses a patient-centric model that departs from traditional service-specific measurements and allows for novel insights into how digital programs benefit patients across the health system. Trial Registration N/A PMID:27080852

Integration of Digital Technologies into Play-Based Pedagogy in Kuwaiti Early Childhood Education: Teachers' Views, Attitudes and Aptitudes

ERIC Educational Resources Information Center

Aldhafeeri, Fayiz; Palaiologou, Ioanna; Folorunsho, Aderonke

2016-01-01

Scholars in the field of early childhood education are still debating the inclusion of digital technologies in play-based pedagogy and our understanding of digital play in early childhood education is still developing. This research paper examines early childhood education teachers' views, aptitudes and attitudes towards digital technologies in…

What Digital Games and Literacy Have in Common: A Heuristic for Understanding Pupils' Gaming Literacy

ERIC Educational Resources Information Center

Apperley, Thomas; Walsh, Christopher

2012-01-01

This article argues that digital games and school-based literacy practices have much more in common than is reported in the research literature. We describe the role digital game paratexts--ancillary print and multimodal texts about digital games--can play in connecting pupils' gaming literacy practices to "traditional" school-based literacies…

Micro-electro-mechanical systems (MEMS) and agile lensing-based modules for communications, sensing and signal processing

NASA Astrophysics Data System (ADS)

Reza, Syed Azer

This dissertation proposes the use of the emerging Micro-Electro-Mechanical Systems (MEMS) and agile lensing optical device technologies to design novel and powerful signal conditioning and sensing modules for advanced applications in optical communications, physical parameter sensing and RF/optical signal processing. For example, these new module designs have experimentally demonstrated exceptional features such as stable loss broadband operations and high > 60 dB optical dynamic range signal filtering capabilities. The first part of the dissertation describes the design and demonstration of digital MEMS-based signal processing modules for communication systems and sensor networks using the TI DLP (Digital Light Processing) technology. Examples of such modules include optical power splitters, narrowband and broadband variable fiber optical attenuators, spectral shapers and filters. Compared to prior works, these all-digital designs have advantages of repeatability, accuracy, and reliability that are essential for advanced communications and sensor applications. The next part of the dissertation proposes, analyzes and demonstrates the use of analog opto-fluidic agile lensing technology for sensor networks and test and measurement systems. Novel optical module designs for distance sensing, liquid level sensing, three-dimensional object shape sensing and variable photonic delay lines are presented and experimentally demonstrated. Compared to prior art module designs, the proposed analog-mode modules have exceptional performances, particularly for extreme environments (e.g., caustic liquids) where the free-space agile beam-based sensor provide remote non-contact access for physical sensing operations. The dissertation also presents novel modules involving hybrid analog-digital photonic designs that make use of the different optical device technologies to deliver the best features of both analog and digital optical device operations and controls. Digital controls are achieved through the use of the digital MEMS technology and analog controls are realized by employing opto-fluidic agile lensing technology and acousto-optic technology. For example, variable fiber-optic attenuators and spectral filters are proposed using the hybrid design. Compared to prior art module designs, these hybrid designs provide a higher module dynamic range and increased resolution that are critical in various advanced system applications. In summary, the dissertation shows the added power of hybrid optical designs using both the digital and analog photonic signal processing versus just all-digital or all-analog module designs.

Evolution of digital angiography systems.

PubMed

Brigida, Raffaela; Misciasci, Teresa; Martarelli, Fabiola; Gangitano, Guido; Ottaviani, Pierfrancesco; Rollo, Massimo; Marano, Pasquale

2003-01-01

The innovations introduced by digital subtraction angiography in digital radiography are briefly illustrated with the description of its components and functioning. The pros and cons of digital subtraction angiography are analyzed in light of present and future imaging technologies. In particular, among advantages there are: automatic exposure, digital image subtraction, digital post-processing, high number of images per second, possible changes in density and contrast. Among disadvantages there are: small round field of view, geometric distortion at the image periphery, high sensitivity to patient movements, not very high spatial resolution. At present, flat panel detectors represent the most suitable substitutes for digital subtraction angiography, with the introduction of novel solutions for those artifacts which for years have hindered its diagnostic validity. The concept of temporal artifact, reset light and possible future evolutions of this technology that may afford both diagnostic and protectionist advantages, are analyzed.

An accurate system for onsite calibration of electronic transformers with digital output.

PubMed

Zhi, Zhang; Li, Hong-Bin

2012-06-01

Calibration systems with digital output are used to replace conventional calibration systems because of principle diversity and characteristics of digital output of electronic transformers. But precision and unpredictable stability limit their onsite application even development. So fully considering the factors influencing accuracy of calibration system and employing simple but reliable structure, an all-digital calibration system with digital output is proposed in this paper. In complicated calibration environments, precision and dynamic range are guaranteed by A/D converter with 24-bit resolution, synchronization error limit is nanosecond by using the novelty synchronization method. In addition, an error correction algorithm based on the differential method by using two-order Hanning convolution window has good inhibition of frequency fluctuation and inter-harmonics interference. To verify the effectiveness, error calibration was carried out in the State Grid Electric Power Research Institute of China and results show that the proposed system can reach the precision class up to 0.05. Actual onsite calibration shows that the system has high accuracy, and is easy to operate with satisfactory stability.

An accurate system for onsite calibration of electronic transformers with digital output

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhi Zhang; Li Hongbin; State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Wuhan 430074

Calibration systems with digital output are used to replace conventional calibration systems because of principle diversity and characteristics of digital output of electronic transformers. But precision and unpredictable stability limit their onsite application even development. So fully considering the factors influencing accuracy of calibration system and employing simple but reliable structure, an all-digital calibration system with digital output is proposed in this paper. In complicated calibration environments, precision and dynamic range are guaranteed by A/D converter with 24-bit resolution, synchronization error limit is nanosecond by using the novelty synchronization method. In addition, an error correction algorithm based on the differentialmore » method by using two-order Hanning convolution window has good inhibition of frequency fluctuation and inter-harmonics interference. To verify the effectiveness, error calibration was carried out in the State Grid Electric Power Research Institute of China and results show that the proposed system can reach the precision class up to 0.05. Actual onsite calibration shows that the system has high accuracy, and is easy to operate with satisfactory stability.« less

An accurate system for onsite calibration of electronic transformers with digital output

NASA Astrophysics Data System (ADS)

Zhi, Zhang; Li, Hong-Bin

2012-06-01

Calibration systems with digital output are used to replace conventional calibration systems because of principle diversity and characteristics of digital output of electronic transformers. But precision and unpredictable stability limit their onsite application even development. So fully considering the factors influencing accuracy of calibration system and employing simple but reliable structure, an all-digital calibration system with digital output is proposed in this paper. In complicated calibration environments, precision and dynamic range are guaranteed by A/D converter with 24-bit resolution, synchronization error limit is nanosecond by using the novelty synchronization method. In addition, an error correction algorithm based on the differential method by using two-order Hanning convolution window has good inhibition of frequency fluctuation and inter-harmonics interference. To verify the effectiveness, error calibration was carried out in the State Grid Electric Power Research Institute of China and results show that the proposed system can reach the precision class up to 0.05. Actual onsite calibration shows that the system has high accuracy, and is easy to operate with satisfactory stability.

4D very high-resolution topography monitoring of surface deformation using UAV-SfM framework.

NASA Astrophysics Data System (ADS)

Clapuyt, François; Vanacker, Veerle; Schlunegger, Fritz; Van Oost, Kristof

2016-04-01

During the last years, exploratory research has shown that UAV-based image acquisition is suitable for environmental remote sensing and monitoring. Image acquisition with cameras mounted on an UAV can be performed at very-high spatial resolution and high temporal frequency in the most dynamic environments. Combined with Structure-from-Motion algorithm, the UAV-SfM framework is capable of providing digital surface models (DSM) which are highly accurate when compared to other very-high resolution topographic datasets and highly reproducible for repeated measurements over the same study area. In this study, we aim at assessing (1) differential movement of the Earth's surface and (2) the sediment budget of a complex earthflow located in the Central Swiss Alps based on three topographic datasets acquired over a period of 2 years. For three time steps, we acquired aerial photographs with a standard reflex camera mounted on a low-cost and lightweight UAV. Image datasets were then processed with the Structure-from-Motion algorithm in order to reconstruct a 3D dense point cloud representing the topography. Georeferencing of outputs has been achieved based on the ground control point (GCP) extraction method, previously surveyed on the field with a RTK GPS. Finally, digital elevation model of differences (DOD) has been computed to assess the topographic changes between the three acquisition dates while surface displacements have been quantified by using image correlation techniques. Our results show that the digital elevation model of topographic differences is able to capture surface deformation at cm-scale resolution. The mean annual displacement of the earthflow is about 3.6 m while the forefront of the landslide has advanced by ca. 30 meters over a period of 18 months. The 4D analysis permits to identify the direction and velocity of Earth movement. Stable topographic ridges condition the direction of the flow with highest downslope movement on steep slopes, and diffuse movement due to lateral sediment flux in the central part of the earthflow.

Efficient Lookup Table-Based Adaptive Baseband Predistortion Architecture for Memoryless Nonlinearity

NASA Astrophysics Data System (ADS)

Ba, Seydou N.; Waheed, Khurram; Zhou, G. Tong

2010-12-01

Digital predistortion is an effective means to compensate for the nonlinear effects of a memoryless system. In case of a cellular transmitter, a digital baseband predistorter can mitigate the undesirable nonlinear effects along the signal chain, particularly the nonlinear impairments in the radiofrequency (RF) amplifiers. To be practically feasible, the implementation complexity of the predistorter must be minimized so that it becomes a cost-effective solution for the resource-limited wireless handset. This paper proposes optimizations that facilitate the design of a low-cost high-performance adaptive digital baseband predistorter for memoryless systems. A comparative performance analysis of the amplitude and power lookup table (LUT) indexing schemes is presented. An optimized low-complexity amplitude approximation and its hardware synthesis results are also studied. An efficient LUT predistorter training algorithm that combines the fast convergence speed of the normalized least mean squares (NLMSs) with a small hardware footprint is proposed. Results of fixed-point simulations based on the measured nonlinear characteristics of an RF amplifier are presented.

Fast contactless vibrating structure characterization using real time field programmable gate array-based digital signal processing: demonstrations with a passive wireless acoustic delay line probe and vision.

PubMed

Goavec-Mérou, G; Chrétien, N; Friedt, J-M; Sandoz, P; Martin, G; Lenczner, M; Ballandras, S

2014-01-01

Vibrating mechanical structure characterization is demonstrated using contactless techniques best suited for mobile and rotating equipments. Fast measurement rates are achieved using Field Programmable Gate Array (FPGA) devices as real-time digital signal processors. Two kinds of algorithms are implemented on FPGA and experimentally validated in the case of the vibrating tuning fork. A first application concerns in-plane displacement detection by vision with sampling rates above 10 kHz, thus reaching frequency ranges above the audio range. A second demonstration concerns pulsed-RADAR cooperative target phase detection and is applied to radiofrequency acoustic transducers used as passive wireless strain gauges. In this case, the 250 ksamples/s refresh rate achieved is only limited by the acoustic sensor design but not by the detection bandwidth. These realizations illustrate the efficiency, interest, and potentialities of FPGA-based real-time digital signal processing for the contactless interrogation of passive embedded probes with high refresh rates.

Laser Based Color Film Recorder System With GaAs Microlaser

NASA Astrophysics Data System (ADS)

Difrancesco, David J.

1989-07-01

In 1984 Pixar's research and development group built and applied to the motion-picture arts at Lucasfilm's ILM facility a three color laser based film scanner/recorder system. The digital film printer is capable of reading and writing 35mm film formats on a variety of film stocks. The system has been used in award-winning special-effects work, and has been operated in a normal production environment since that time. The primary objective was to develop a full color high resolution system, free from scan artifacts, enabling traditionally photographed motion-picture film to be inter-cut with digital raster image photography. Its use is applied to the art of blue-screen traveling-matte cinematography for motion pic-ture special effects. The system was designed using the Pixar Image Computer and conventional gas laser technology as the illumination source. This paper will discuss recent experimental work in the application of GaAs microlaser technology to a digital film printing system of the future.

Implementation of age and gender recognition system for intelligent digital signage

NASA Astrophysics Data System (ADS)

Lee, Sang-Heon; Sohn, Myoung-Kyu; Kim, Hyunduk

2015-12-01

Intelligent digital signage systems transmit customized advertising and information by analyzing users and customers, unlike existing system that presented advertising in the form of broadcast without regard to type of customers. Currently, development of intelligent digital signage system has been pushed forward vigorously. In this study, we designed a system capable of analyzing gender and age of customers based on image obtained from camera, although there are many different methods for analyzing customers. We conducted age and gender recognition experiments using public database. The age/gender recognition experiments were performed through histogram matching method by extracting Local binary patterns (LBP) features after facial area on input image was normalized. The results of experiment showed that gender recognition rate was as high as approximately 97% on average. Age recognition was conducted based on categorization into 5 age classes. Age recognition rates for women and men were about 67% and 68%, respectively when that conducted separately for different gender.

Computer-based desktop system for surgical videotape editing.

PubMed

Vincent-Hamelin, E; Sarmiento, J M; de la Puente, J M; Vicente, M

1997-05-01

The educational role of surgical video presentations should be optimized by linking surgical images to graphic evaluation of indications, techniques, and results. We describe a PC-based video production system for personal editing of surgical tapes, according to the objectives of each presentation. The hardware requirement is a personal computer (100 MHz processor, 1-Gb hard disk, 16 Mb RAM) with a PC-to-TV/video transfer card plugged into a slot. Computer-generated numerical data, texts, and graphics are transformed into analog signals displayed on TV/video. A Genlock interface (a special interface card) synchronizes digital and analog signals, to overlay surgical images to electronic illustrations. The presentation is stored as digital information or recorded on a tape. The proliferation of multimedia tools is leading us to adapt presentations to the objectives of lectures and to integrate conceptual analyses with dynamic image-based information. We describe a system that handles both digital and analog signals, production being recorded on a tape. Movies may be managed in a digital environment, with either an "on-line" or "off-line" approach. System requirements are high, but handling a single device optimizes editing without incurring such complexity that management becomes impractical to surgeons. Our experience suggests that computerized editing allows linking surgical scientific and didactic messages on a single communication medium, either a videotape or a CD-ROM.

Quantifying seasonal variation of leaf area index using near-infrared digital camera in a rice paddy

NASA Astrophysics Data System (ADS)

Hwang, Y.; Ryu, Y.; Kim, J.

2017-12-01

Digital camera has been widely used to quantify leaf area index (LAI). Numerous simple and automatic methods have been proposed to improve the digital camera based LAI estimates. However, most studies in rice paddy relied on arbitrary thresholds or complex radiative transfer models to make binary images. Moreover, only a few study reported continuous, automatic observation of LAI over the season in rice paddy. The objective of this study is to quantify seasonal variations of LAI using raw near-infrared (NIR) images coupled with a histogram shape-based algorithm in a rice paddy. As vegetation highly reflects the NIR light, we installed NIR digital camera 1.8 m above the ground surface and acquired unsaturated raw format images at one-hour intervals between 15 to 80 º solar zenith angles over the entire growing season in 2016 (from May to September). We applied a sub-pixel classification combined with light scattering correction method. Finally, to confirm the accuracy of the quantified LAI, we also conducted direct (destructive sampling) and indirect (LAI-2200) manual observations of LAI once per ten days on average. Preliminary results show that NIR derived LAI agreed well with in-situ observations but divergence tended to appear once rice canopy is fully developed. The continuous monitoring of LAI in rice paddy will help to understand carbon and water fluxes better and evaluate satellite based LAI products.

A digital optical phase-locked loop for diode lasers based on field programmable gate array

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu Zhouxiang; Zhang Xian; Huang Kaikai

2012-09-15

We have designed and implemented a highly digital optical phase-locked loop (OPLL) for diode lasers in atom interferometry. The three parts of controlling circuit in this OPLL, including phase and frequency detector (PFD), loop filter and proportional integral derivative (PID) controller, are implemented in a single field programmable gate array chip. A structure type compatible with the model MAX9382/MCH12140 is chosen for PFD and pipeline and parallelism technology have been adapted in PID controller. Especially, high speed clock and twisted ring counter have been integrated in the most crucial part, the loop filter. This OPLL has the narrow beat notemore » line width below 1 Hz, residual mean-square phase error of 0.14 rad{sup 2} and transition time of 100 {mu}s under 10 MHz frequency step. A main innovation of this design is the completely digitalization of the whole controlling circuit in OPLL for diode lasers.« less

Coincidence ion imaging with a fast frame camera

NASA Astrophysics Data System (ADS)

Lee, Suk Kyoung; Cudry, Fadia; Lin, Yun Fei; Lingenfelter, Steven; Winney, Alexander H.; Fan, Lin; Li, Wen

2014-12-01

A new time- and position-sensitive particle detection system based on a fast frame CMOS (complementary metal-oxide semiconductors) camera is developed for coincidence ion imaging. The system is composed of four major components: a conventional microchannel plate/phosphor screen ion imager, a fast frame CMOS camera, a single anode photomultiplier tube (PMT), and a high-speed digitizer. The system collects the positional information of ions from a fast frame camera through real-time centroiding while the arrival times are obtained from the timing signal of a PMT processed by a high-speed digitizer. Multi-hit capability is achieved by correlating the intensity of ion spots on each camera frame with the peak heights on the corresponding time-of-flight spectrum of a PMT. Efficient computer algorithms are developed to process camera frames and digitizer traces in real-time at 1 kHz laser repetition rate. We demonstrate the capability of this system by detecting a momentum-matched co-fragments pair (methyl and iodine cations) produced from strong field dissociative double ionization of methyl iodide.

Automated digital magnetofluidics

NASA Astrophysics Data System (ADS)

Schneider, J.; Garcia, A. A.; Marquez, M.

2008-08-01

Drops can be moved in complex patterns on superhydrophobic surfaces using a reconfigured computer-controlled x-y metrology stage with a high degree of accuracy, flexibility, and reconfigurability. The stage employs a DMC-4030 controller which has a RISC-based, clock multiplying processor with DSP functions, accepting encoder inputs up to 22 MHz, provides servo update rates as high as 32 kHz, and processes commands at rates as fast as 40 milliseconds. A 6.35 mm diameter cylindrical NdFeB magnet is translated by the stage causing water drops to move by the action of induced magnetization of coated iron microspheres that remain in the drop and are attracted to the rare earth magnet through digital magnetofluidics. Water drops are easily moved in complex patterns in automated digital magnetofluidics at an average speed of 2.8 cm/s over a superhydrophobic polyethylene surface created by solvent casting. With additional components, some potential uses for this automated microfluidic system include characterization of superhydrophobic surfaces, water quality analysis, and medical diagnostics.

Rapid detection of single bacteria in unprocessed blood using Integrated Comprehensive Droplet Digital Detection

PubMed Central

Kang, Dong-Ku; Ali, M. Monsur; Zhang, Kaixiang; Huang, Susan S.; Peterson, Ellena; Digman, Michelle A.; Gratton, Enrico; Zhao, Weian

2014-01-01

Blood stream infection or sepsis is a major health problem worldwide, with extremely high mortality, which is partly due to the inability to rapidly detect and identify bacteria in the early stages of infection. Here we present a new technology termed ‘Integrated Comprehensive Droplet Digital Detection’ (IC 3D) that can selectively detect bacteria directly from milliliters of diluted blood at single-cell sensitivity in a one-step, culture- and amplification-free process within 1.5–4 h. The IC 3D integrates real-time, DNAzyme-based sensors, droplet microencapsulation and a high-throughput 3D particle counter system. Using Escherichia coli as a target, we demonstrate that the IC 3D can provide absolute quantification of both stock and clinical isolates of E. coli in spiked blood within a broad range of extremely low concentration from 1 to 10,000 bacteria per ml with exceptional robustness and limit of detection in the single digit regime. PMID:25391809

MICROROC: MICRO-mesh gaseous structure Read-Out Chip

NASA Astrophysics Data System (ADS)

Adloff, C.; Blaha, J.; Chefdeville, M.; Dalmaz, A.; Drancourt, C.; Dulucq, F.; Espargilière, A.; Gaglione, R.; Geffroy, N.; Jacquemier, J.; Karyotakis, Y.; Martin-Chassard, G.; Prast, J.; Seguin-Moreau, N.; de La Taille, Ch; Vouters, G.

2012-01-01

MICRO MEsh GAseous Structure (MICROMEGAS) and Gas Electron Multipliers (GEM) detectors are two candidates for the active medium of a Digital Hadronic CALorimeter (DHCAL) as part of a high energy physics experiment at a future linear collider (ILC/CLIC). Physics requirements lead to a highly granular hadronic calorimeter with up to thirty million channels with probably only hit information (digital readout calorimeter). To validate the concept of digital hadronic calorimetry with such small cell size, the construction and test of a cubic meter technological prototype, made of 40 planes of one square meter each, is necessary. This technological prototype would contain about 400 000 electronic channels, thus requiring the development of front-end ASIC. Based on the experience gained with previous ASIC that were mounted on detectors and tested in particle beams, a new ASIC called MICROROC has been developped. This paper summarizes the caracterisation campaign that was conducted on this new chip as well as its integration into a large area Micromegas chamber of one square meter.

Property-Based Monitoring of Analog and Mixed-Signal Systems

NASA Astrophysics Data System (ADS)

Havlicek, John; Little, Scott; Maler, Oded; Nickovic, Dejan

In the recent past, there has been a steady growth of the market for consumer embedded devices such as cell phones, GPS and portable multimedia systems. In embedded systems, digital, analog and software components are combined on a single chip, resulting in increasingly complex designs that introduce richer functionality on smaller devices. As a consequence, the potential insertion of errors into a design becomes higher, yielding an increasing need for automated analog and mixed-signal validation tools. In the purely digital setting, formal verification based on properties expressed in industrial specification languages such as PSL and SVA is nowadays successfully integrated in the design flow. On the other hand, the validation of analog and mixed-signal systems still largely depends on simulation-based, ad-hoc methods. In this tutorial, we consider some ingredients of the standard verification methodology that can be successfully exported from digital to analog and mixed-signal setting, in particular property-based monitoring techniques. Property-based monitoring is a lighter approach to the formal verification, where the system is seen as a "black-box" that generates sets of traces, whose correctness is checked against a property, that is its high-level specification. Although incomplete, monitoring is effectively used to catch faults in systems, without guaranteeing their full correctness.

Next-Generation A/D Sampler ADS3000+ for VLBI2010

NASA Technical Reports Server (NTRS)

Takefuji, Kazuhiro; Takeuchi, Hiroshi; Tsutsumi, Masanori; Koyama, Yasuhiro

2010-01-01

A high-speed A/D sampler, called ADS3000+, has been developed in 2008, which can sample one analog signal up to 4 Gbps to versatile Linux PC. After A/D conversion, the ADS3000+ can perform digital signal processing such as real-time DBBC (Digital Base Band Conversion) and FIR filtering such as simple CW RFI filtering using the installed FPGAs. A 4 Gsps fringe test with the ADS3000+ has been successfully performed. The ADS3000+ will not exclusively be used for VLBI but will also be employed in other applications.

Optical encryption interface

NASA Technical Reports Server (NTRS)

Jackson, Deborah J. (Inventor)

1998-01-01

An analog optical encryption system based on phase scrambling of two-dimensional optical images and holographic transformation for achieving large encryption keys and high encryption speed. An enciphering interface uses a spatial light modulator for converting a digital data stream into a two dimensional optical image. The optical image is further transformed into a hologram with a random phase distribution. The hologram is converted into digital form for transmission over a shared information channel. A respective deciphering interface at a receiver reverses the encrypting process by using a phase conjugate reconstruction of the phase scrambled hologram.

Comparison of digital signal processing modules in gamma-ray spectrometry.

PubMed

Lépy, Marie-Christine; Cissé, Ousmane Ibrahima; Pierre, Sylvie

2014-05-01

Commercial digital signal-processing modules have been tested for their applicability to gamma-ray spectrometry. The tests were based on the same n-type high purity germanium detector. The spectrum quality was studied in terms of energy resolution and peak area versus shaping parameters, using a Eu-152 point source. The stability of a reference peak count rate versus the total count rate was also examined. The reliability of the quantitative results is discussed for their use in measurement at the metrological level. © 2013 Published by Elsevier Ltd.

Information technology in the foxhole.

PubMed

Eyestone, S M

1995-08-01

The importance of digital data capture at the point of health care service within the military environment is highlighted. Current paper-based data capture does not allow for efficient data reuse throughout the medical support information domain. A simple, high-level process and data flow model is used to demonstrate the importance of data capture at point of service. The Department of Defense is developing a personal digital assistant, called MEDTAG, that accomplishes point of service data capture in the field using a prototype smart card as a data store in austere environments.

Flight-test experience in digital control of a remotely piloted vehicle.

NASA Technical Reports Server (NTRS)

Edwards, J. W.

1972-01-01

The development of a remotely piloted vehicle system consisting of a remote pilot cockpit and a ground-based digital computer coupled to the aircraft through telemetry data links is described. The feedback control laws are implemented in a FORTRAN program. Flight-test experience involving high feedback gain limits for attitude and attitude rate feedback variables, filtering of sampled data, and system operation during intermittent telemetry data link loss is discussed. Comparisons of closed-loop flight tests with analytical calculations, and pilot comments on system operation are included.

Classification of Chemicals Based On Structured Toxicity Information

EPA Science Inventory

Thirty years and millions of dollars worth of pesticide registration toxicity studies, historically stored as hardcopy and scanned documents, have been digitized into highly standardized and structured toxicity data within the Toxicity Reference Database (ToxRefDB). Toxicity-bas...

Rapid orthophoto development system.

DOT National Transportation Integrated Search

2013-06-01

The DMC system procured in the project represented state-of-the-art, large-format digital aerial camera systems at the start of : project. DMC is based on the frame camera model, and to achieve large ground coverage with high spatial resolution, the ...

Integration of near-surface remote sensing and eddy covariance measurements: new insights on managed ecosystem structure and functioning

NASA Astrophysics Data System (ADS)

Hatala, J.; Sonnentag, O.; Detto, M.; Runkle, B.; Vargas, R.; Kelly, M.; Baldocchi, D. D.

2009-12-01

Ground-based, visible light imagery has been used for different purposes in agricultural and ecological research. A series of recent studies explored the utilization of networked digital cameras to continuously monitor vegetation by taking oblique canopy images at fixed view angles and time intervals. In our contribution we combine high temporal resolution digital camera imagery, eddy-covariance, and meteorological measurements with weekly field-based hyperspectral and LAI measurements to gain new insights on temporal changes in canopy structure and functioning of two managed ecosystems in California’s Sacramento-San Joaquin River Delta: a pasture infested by the invasive perennial pepperweed (Lepidium latifolium) and a rice plantation (Oryza sativa). Specific questions we address are: a) how does year-round grazing affect pepperweed canopy development, b) is it possible to identify phenological key events of managed ecosystems (pepperweed: flowering; rice: heading) from the limited spectral information of digital camera imagery, c) is a simple greenness index derived from digital camera imagery sufficient to track leaf area index and canopy development of managed ecosystems, and d) what are the scales of temporal correlation between digital camera signals and carbon and water fluxes of managed ecosystems? Preliminary results for the pasture-pepperweed ecosystem show that year-round grazing inhibits the accumulation of dead stalks causing earlier green-up and that digital camera imagery is well suited to capture the onset of flowering and the associated decrease in photosynthetic CO2 uptake. Results from our analyses are of great relevance from both a global environmental change and land management perspective.

Development of an MRI-compatible digital SiPM detector stack for simultaneous PET/MRI.

PubMed

Düppenbecker, Peter M; Weissler, Bjoern; Gebhardt, Pierre; Schug, David; Wehner, Jakob; Marsden, Paul K; Schulz, Volkmar

2016-02-01

Advances in solid-state photon detectors paved the way to combine positron emission tomography (PET) and magnetic resonance imaging (MRI) into highly integrated, truly simultaneous, hybrid imaging systems. Based on the most recent digital SiPM technology, we developed an MRI-compatible PET detector stack, intended as a building block for next generation simultaneous PET/MRI systems. Our detector stack comprises an array of 8 × 8 digital SiPM channels with 4 mm pitch using Philips Digital Photon Counting DPC 3200-22 devices, an FPGA for data acquisition, a supply voltage control system and a cooling infrastructure. This is the first detector design that allows the operation of digital SiPMs simultaneously inside an MRI system. We tested and optimized the MRI-compatibility of our detector stack on a laboratory test bench as well as in combination with a Philips Achieva 3 T MRI system. Our design clearly reduces distortions of the static magnetic field compared to a conventional design. The MRI static magnetic field causes weak and directional drift effects on voltage regulators, but has no direct impact on detector performance. MRI gradient switching initially degraded energy and timing resolution. Both distortions could be ascribed to voltage variations induced on the bias and the FPGA core voltage supply respectively. Based on these findings, we improved our detector design and our final design shows virtually no energy or timing degradations, even during heavy and continuous MRI gradient switching. In particular, we found no evidence that the performance of the DPC 3200-22 digital SiPM itself is degraded by the MRI system.

Orientations in adolescent use of information and communication technology: a digital divide by sociodemographic background, educational career, and health.

PubMed

Koivusilta, Leena K; Lintonen, Tomi P; Rimpelä, Arja H

2007-01-01

The role of information and communication technology (ICT) in adolescents' lives was studied, with emphasis on whether there exists a digital divide based on sociodemographic background, educational career, and health. The assumption was that some groups of adolescents use ICT more so that their information utilization skills improve (computer use), while others use it primarily for entertainment (digital gaming, contacting friends by mobile phone). Data were collected by mailed survey from a nationally representative sample of 12- to 18-year-olds (n=7,292; response 70%) in 2001 and analysed using ANOVA. Computer use was most frequent among adolescents whose fathers had higher education or socioeconomic status, who came from nuclear families, and who continued studies after compulsory education. Digital gaming was associated with poor school achievement and attending vocational rather than upper secondary school. Mobile phone use was frequent among adolescents whose fathers had lower education or socioeconomic status, who came from non-nuclear families, and whose educational prospects were poor. Intensive use of each ICT form, especially of mobile phones, was associated with health problems. High social position, nuclear family, and a successful educational career signified good health in general, independently of the diverse usage of ICT. There exists a digital divide among adolescents: orientation to computer use is more common in educated well-off families while digital gaming and mobile phone use accumulate at the opposite end of the spectrum. Poorest health was reported by mobile phone users. High social background and success at school signify better health, independently of the ways of using ICT.