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Sample records for dim-light vision proteins

  1. Limits of colour vision in dim light.

    PubMed

    Kelber, Almut; Lind, Olle

    2010-09-01

    Humans and most vertebrates have duplex retinae with multiple cone types for colour vision in bright light, and one single rod type for achromatic vision in dim light. Instead of comparing signals from multiple spectral types of photoreceptors, such species use one highly sensitive receptor type thus improving the signal-to-noise ratio at night. However, the nocturnal hawkmoth Deilephila elpenor, the nocturnal bee Xylocopa tranquebarica and the nocturnal gecko Tarentola chazaliae can discriminate colours at extremely dim light intensities. To be able to do so, they sacrifice spatial and temporal resolution in favour of colour vision. We review what is known about colour vision in dim light, and compare colour vision thresholds with the optical sensitivity of the photoreceptors in selected animal species with lens and compound eyes. © 2010 The Authors, Ophthalmic and Physiological Optics © 2010 The College of Optometrists.

  2. Elucidation of phenotypic adaptations: Molecular analyses of dim-light vision proteins in vertebrates

    PubMed Central

    Yokoyama, Shozo; Tada, Takashi; Zhang, Huan; Britt, Lyle

    2008-01-01

    Vertebrate ancestors appeared in a uniform, shallow water environment, but modern species flourish in highly variable niches. A striking array of phenotypes exhibited by contemporary animals is assumed to have evolved by accumulating a series of selectively advantageous mutations. However, the experimental test of such adaptive events at the molecular level is remarkably difficult. One testable phenotype, dim-light vision, is mediated by rhodopsins. Here, we engineered 11 ancestral rhodopsins and show that those in early ancestors absorbed light maximally (λmax) at 500 nm, from which contemporary rhodopsins with variable λmaxs of 480–525 nm evolved on at least 18 separate occasions. These highly environment-specific adaptations seem to have occurred largely by amino acid replacements at 12 sites, and most of those at the remaining 191 (≈94%) sites have undergone neutral evolution. The comparison between these results and those inferred by commonly-used parsimony and Bayesian methods demonstrates that statistical tests of positive selection can be misleading without experimental support and that the molecular basis of spectral tuning in rhodopsins should be elucidated by mutagenesis analyses using ancestral pigments. PMID:18768804

  3. Oligomeric State of Purified Transient Receptor Potential Melastatin-1 (TRPM1), a Protein Essential for Dim Light Vision*

    PubMed Central

    Agosto, Melina A.; Zhang, Zhixian; He, Feng; Anastassov, Ivan A.; Wright, Sara J.; McGehee, Jennifer; Wensel, Theodore G.

    2014-01-01

    Transient receptor potential melastatin-1 (TRPM1) is essential for the light-induced depolarization of retinal ON bipolar cells. TRPM1 likely forms a multimeric channel complex, although almost nothing is known about the structure or subunit composition of channels formed by TRPM1 or any of its close relatives. Recombinant TRPM1 was robustly expressed in insect cells, but only a small fraction was localized to the plasma membrane. Similar intracellular localization was observed when TRPM1 was heterologously expressed in mammalian cells. TRPM1 was affinity-purified from Sf9 cells and complexed with amphipol, followed by detergent removal. In blue native gels and size exclusion chromatography, TRPM1 migrated with a mobility consistent with detergent- or amphipol-bound dimers. Cross-linking experiments were also consistent with a dimeric subunit stoichiometry, and cryoelectron microscopy and single particle analysis without symmetry imposition yielded a model with approximate 2-fold symmetrical features. Finally, electron microscopy of TRPM1-antibody complexes revealed a large particle that can accommodate TRPM1 and two antibody molecules. Taken together, these data indicate that purified TRPM1 is mostly dimeric. The three-dimensional structure of TRPM1 dimers is characterized by a small putative transmembrane domain and a larger domain with a hollow cavity. Blue native gels of solubilized mouse retina indicate that TRPM1 is present in two distinct complexes: one similar in size to the recombinant protein and one much larger. Because dimers are likely not functional ion channels, these results suggest that additional partner subunits participate in forming the transduction channel required for dim light vision and the ON pathway. PMID:25112866

  4. Oligomeric state of purified transient receptor potential melastatin-1 (TRPM1), a protein essential for dim light vision.

    PubMed

    Agosto, Melina A; Zhang, Zhixian; He, Feng; Anastassov, Ivan A; Wright, Sara J; McGehee, Jennifer; Wensel, Theodore G

    2014-09-26

    Transient receptor potential melastatin-1 (TRPM1) is essential for the light-induced depolarization of retinal ON bipolar cells. TRPM1 likely forms a multimeric channel complex, although almost nothing is known about the structure or subunit composition of channels formed by TRPM1 or any of its close relatives. Recombinant TRPM1 was robustly expressed in insect cells, but only a small fraction was localized to the plasma membrane. Similar intracellular localization was observed when TRPM1 was heterologously expressed in mammalian cells. TRPM1 was affinity-purified from Sf9 cells and complexed with amphipol, followed by detergent removal. In blue native gels and size exclusion chromatography, TRPM1 migrated with a mobility consistent with detergent- or amphipol-bound dimers. Cross-linking experiments were also consistent with a dimeric subunit stoichiometry, and cryoelectron microscopy and single particle analysis without symmetry imposition yielded a model with approximate 2-fold symmetrical features. Finally, electron microscopy of TRPM1-antibody complexes revealed a large particle that can accommodate TRPM1 and two antibody molecules. Taken together, these data indicate that purified TRPM1 is mostly dimeric. The three-dimensional structure of TRPM1 dimers is characterized by a small putative transmembrane domain and a larger domain with a hollow cavity. Blue native gels of solubilized mouse retina indicate that TRPM1 is present in two distinct complexes: one similar in size to the recombinant protein and one much larger. Because dimers are likely not functional ion channels, these results suggest that additional partner subunits participate in forming the transduction channel required for dim light vision and the ON pathway.

  5. Thresholds and noise limitations of colour vision in dim light.

    PubMed

    Kelber, Almut; Yovanovich, Carola; Olsson, Peter

    2017-04-05

    Colour discrimination is based on opponent photoreceptor interactions, and limited by receptor noise. In dim light, photon shot noise impairs colour vision, and in vertebrates, the absolute threshold of colour vision is set by dark noise in cones. Nocturnal insects (e.g. moths and nocturnal bees) and vertebrates lacking rods (geckos) have adaptations to reduce receptor noise and use chromatic vision even in very dim light. In contrast, vertebrates with duplex retinae use colour-blind rod vision when noisy cone signals become unreliable, and their transition from cone- to rod-based vision is marked by the Purkinje shift. Rod-cone interactions have not been shown to improve colour vision in dim light, but may contribute to colour vision in mesopic light intensities. Frogs and toads that have two types of rods use opponent signals from these rods to control phototaxis even at their visual threshold. However, for tasks such as prey or mate choice, their colour discrimination abilities fail at brighter light intensities, similar to other vertebrates, probably limited by the dark noise in cones.This article is part of the themed issue 'Vision in dim light'.

  6. Optimum spatiotemporal receptive fields for vision in dim light.

    PubMed

    Klaus, Andreas; Warrant, Eric J

    2009-04-22

    Many nocturnal insects depend on vision for daily life and have evolved different strategies to improve their visual capabilities in dim light. Neural summation of visual signals is one strategy to improve visual performance, and this is likely to be especially important for insects with apposition compound eyes. Here we develop a model to determine the optimum spatiotemporal sampling of natural scenes at gradually decreasing light levels. Image anisotropy has a strong influence on the receptive field properties predicted to be optimal at low light intensities. Spatial summation between visual channels is predicted to extend more strongly in the direction with higher correlations between the input signals. Increased spatiotemporal summation increases signal-to-noise ratio at low frequencies but sacrifices signal-to-noise ratio at higher frequencies. These results, while obtained from a model of the insect visual system, are likely to apply to visual systems in general.

  7. Ocellar adaptations for dim light vision in a nocturnal bee.

    PubMed

    Berry, Richard P; Wcislo, William T; Warrant, Eric J

    2011-04-15

    Growing evidence indicates that insect ocelli are strongly adapted to meet the specific functional requirements in the environment in which that insect lives. We investigated how the ocelli of the nocturnal bee Megalopta genalis are adapted to life in the dim understory of a tropical rainforest. Using a combination of light microscopy and three-dimensional reconstruction, we found that the retinae contain bar-shaped rhabdoms loosely arranged in a radial pattern around multi-layered lenses, and that both lenses and retinae form complex non-spherical shapes reminiscent of those described in other ocelli. Intracellular electrophysiology revealed that the photoreceptors have high absolute sensitivity, but that the threshold location varied widely between 10(9) and 10(11) photons cm(-2) s(-1). Higher sensitivity and greater visual reliability may be obtained at the expense of temporal resolution: the corner frequencies of dark-adapted ocellar photoreceptors were just 4-11 Hz. Spectral sensitivity profiles consistently peaked at 500 nm. Unlike the ocelli of other flying insects, we did not detect UV-sensitive visual pigments in M. genalis, which may be attributable to a scarcity of UV photons under the rainforest canopy at night. In contrast to earlier predictions based on anatomy, the photoreceptors are not sensitive to the e-vector of polarised light. Megalopta genalis ocellar photoreceptors possess a number of unusual properties, including inherently high response variability and the ability to produce spike-like potentials. These properties bear similarities to photoreceptors in the compound eye of the cockroach, and we suggest that the two insects share physiological characteristics optimised for vision in dim light.

  8. Neural Summation in the Hawkmoth Visual System Extends the Limits of Vision in Dim Light.

    PubMed

    Stöckl, Anna Lisa; O'Carroll, David Charles; Warrant, Eric James

    2016-03-21

    Most of the world's animals are active in dim light and depend on good vision for the tasks of daily life. Many have evolved visual adaptations that permit a performance superior to that of manmade imaging devices [1]. In insects, a major model visual system, nocturnal species show impressive visual abilities ranging from flight control [2, 3], to color discrimination [4, 5], to navigation using visual landmarks [6-8] or dim celestial compass cues [9, 10]. In addition to optical adaptations that improve their sensitivity in dim light [11], neural summation of light in space and time-which enhances the coarser and slower features of the scene at the expense of noisier finer and faster features-has been suggested to improve sensitivity in theoretical [12-14], anatomical [15-17], and behavioral [18-20] studies. How these summation strategies function neurally is, however, presently unknown. Here, we quantified spatial and temporal summation in the motion vision pathway of a nocturnal hawkmoth. We show that spatial and temporal summation combine supralinearly to substantially increase contrast sensitivity and visual information rate over four decades of light intensity, enabling hawkmoths to see at light levels 100 times dimmer than without summation. Our results reveal how visual motion is calculated neurally in dim light and how spatial and temporal summation improve sensitivity while simultaneously maximizing spatial and temporal resolution, thus extending models of insect motion vision derived predominantly from diurnal flies. Moreover, the summation strategies we have revealed may benefit manmade vision systems optimized for variable light levels [21].

  9. The eyes of lanternfishes (Myctophidae, Teleostei): novel ocular specializations for vision in dim light.

    PubMed

    de Busserolles, Fanny; Marshall, N Justin; Collin, Shaun P

    2014-05-01

    Lanternfishes are one of the most abundant groups of mesopelagic fishes in the world's oceans and play a critical role in biomass vertical turnover. Despite their importance, very little is known about their physiology or how they use their sensory systems to survive in the extreme conditions of the deep sea. In this study, we provide a comprehensive description of the general morphology of the myctophid eye, based on analysis of 53 different species, to understand better their visual capabilities. Results confirm that myctophids possess several visual adaptations for dim-light conditions, including enlarged eyes, an aphakic gap, a tapetum lucidum, and a pure rod retina with high densities of long photoreceptors. Two novel retinal specializations were also discovered. The first specialization is a fundal pigmentation in adult eyes, found within an isolated retinal region (typically central retina) composed of modified pigment epithelial cells, which we hypothesize to be the remnant of a more pronounced visual specialization important in larval stages. The second specialization is an aggregation of extracellular microtubular-like structures found within the sclerad region of the inner nuclear layer of the retina. We hypothesize that the marked interspecific differences in the hypertrophy of these microtubular-like structures may be related to inherent differences in visual function. A general interspecific variability in other parts of the eye is also revealed and examined in this study. The contribution of both ecology and phylogeny to the evolution of ocular specializations and vision in dim light are discussed.

  10. Comparative system identification of flower tracking performance in three hawkmoth species reveals adaptations for dim light vision.

    PubMed

    Stöckl, Anna L; Kihlström, Klara; Chandler, Steven; Sponberg, Simon

    2017-04-05

    Flight control in insects is heavily dependent on vision. Thus, in dim light, the decreased reliability of visual signal detection also prompts consequences for insect flight. We have an emerging understanding of the neural mechanisms that different species employ to adapt the visual system to low light. However, much less explored are comparative analyses of how low light affects the flight behaviour of insect species, and the corresponding links between physiological adaptations and behaviour. We investigated whether the flower tracking behaviour of three hawkmoth species with different diel activity patterns revealed luminance-dependent adaptations, using a system identification approach. We found clear luminance-dependent differences in flower tracking in all three species, which were explained by a simple luminance-dependent delay model, which generalized across species. We discuss physiological and anatomical explanations for the variance in tracking responses, which could not be explained by such simple models. Differences between species could not be explained by the simple delay model. However, in several cases, they could be explained through the addition on a second model parameter, a simple scaling term, that captures the responsiveness of each species to flower movements. Thus, we demonstrate here that much of the variance in the luminance-dependent flower tracking responses of hawkmoths with different diel activity patterns can be captured by simple models of neural processing.This article is part of the themed issue 'Vision in dim light'.

  11. Divergence of dim-light vision among bats (order: Chiroptera) as estimated by molecular and electrophysiological methods.

    PubMed

    Liu, He-Qun; Wei, Jing-Kuan; Li, Bo; Wang, Ming-Shan; Wu, Rui-Qi; Rizak, Joshua D; Zhong, Li; Wang, Lu; Xu, Fu-Qiang; Shen, Yong-Yi; Hu, Xin-Tian; Zhang, Ya-Ping

    2015-06-23

    Dim-light vision is present in all bats, but is divergent among species. Old-World fruit bats (Pteropodidae) have fully developed eyes; the eyes of insectivorous bats are generally degraded, and these bats rely on well-developed echolocation. An exception is the Emballonuridae, which are capable of laryngeal echolocation but prefer to use vision for navigation and have normal eyes. In this study, integrated methods, comprising manganese-enhanced magnetic resonance imaging (MEMRI), f-VEP and RNA-seq, were utilized to verify the divergence. The results of MEMRI showed that Pteropodidae bats have a much larger superior colliculus (SC)/ inferior colliculus (IC) volume ratio (3:1) than insectivorous bats (1:7). Furthermore, the absolute visual thresholds (log cd/m(2)•s) of Pteropodidae (-6.30 and -6.37) and Emballonuridae (-3.71) bats were lower than those of other insectivorous bats (-1.90). Finally, genes related to the visual pathway showed signs of positive selection, convergent evolution, upregulation and similar gene expression patterns in Pteropodidae and Emballonuridae bats. Different results imply that Pteropodidae and Emballonuridae bats have more developed vision than the insectivorous bats and suggest that further research on bat behavior is warranted.

  12. Divergence of dim-light vision among bats (order: Chiroptera) as estimated by molecular and electrophysiological methods

    PubMed Central

    Liu, He-Qun; Wei, Jing-Kuan; Li, Bo; Wang, Ming-Shan; Wu, Rui-Qi; Rizak, Joshua D.; Zhong, Li; Wang, Lu; Xu, Fu-Qiang; Shen, Yong-Yi; Hu, Xin-Tian; Zhang, Ya-Ping

    2015-01-01

    Dim-light vision is present in all bats, but is divergent among species. Old-World fruit bats (Pteropodidae) have fully developed eyes; the eyes of insectivorous bats are generally degraded, and these bats rely on well-developed echolocation. An exception is the Emballonuridae, which are capable of laryngeal echolocation but prefer to use vision for navigation and have normal eyes. In this study, integrated methods, comprising manganese-enhanced magnetic resonance imaging (MEMRI), f-VEP and RNA-seq, were utilized to verify the divergence. The results of MEMRI showed that Pteropodidae bats have a much larger superior colliculus (SC)/ inferior colliculus (IC) volume ratio (3:1) than insectivorous bats (1:7). Furthermore, the absolute visual thresholds (log cd/m2•s) of Pteropodidae (−6.30 and −6.37) and Emballonuridae (−3.71) bats were lower than those of other insectivorous bats (−1.90). Finally, genes related to the visual pathway showed signs of positive selection, convergent evolution, upregulation and similar gene expression patterns in Pteropodidae and Emballonuridae bats. Different results imply that Pteropodidae and Emballonuridae bats have more developed vision than the insectivorous bats and suggest that further research on bat behavior is warranted. PMID:26100095

  13. Parallel and convergent evolution of the dim-light vision gene RH1 in bats (Order: Chiroptera).

    PubMed

    Shen, Yong-Yi; Liu, Jie; Irwin, David M; Zhang, Ya-Ping

    2010-01-21

    Rhodopsin, encoded by the gene Rhodopsin (RH1), is extremely sensitive to light, and is responsible for dim-light vision. Bats are nocturnal mammals that inhabit poor light environments. Megabats (Old-World fruit bats) generally have well-developed eyes, while microbats (insectivorous bats) have developed echolocation and in general their eyes were degraded, however, dramatic differences in the eyes, and their reliance on vision, exist in this group. In this study, we examined the rod opsin gene (RH1), and compared its evolution to that of two cone opsin genes (SWS1 and M/LWS). While phylogenetic reconstruction with the cone opsin genes SWS1 and M/LWS generated a species tree in accord with expectations, the RH1 gene tree united Pteropodidae (Old-World fruit bats) and Yangochiroptera, with very high bootstrap values, suggesting the possibility of convergent evolution. The hypothesis of convergent evolution was further supported when nonsynonymous sites or amino acid sequences were used to construct phylogenies. Reconstructed RH1 sequences at internal nodes of the bat species phylogeny showed that: (1) Old-World fruit bats share an amino acid change (S270G) with the tomb bat; (2) Miniopterus share two amino acid changes (V104I, M183L) with Rhinolophoidea; (3) the amino acid replacement I123V occurred independently on four branches, and the replacements L99M, L266V and I286V occurred each on two branches. The multiple parallel amino acid replacements that occurred in the evolution of bat RH1 suggest the possibility of multiple convergences of their ecological specialization (i.e., various photic environments) during adaptation for the nocturnal lifestyle, and suggest that further attention is needed on the study of the ecology and behavior of bats.

  14. The molecular origin and evolution of dim-light vision in mammals.

    PubMed

    Bickelmann, Constanze; Morrow, James M; Du, Jing; Schott, Ryan K; van Hazel, Ilke; Lim, Steve; Müller, Johannes; Chang, Belinda S W

    2015-11-01

    The nocturnal origin of mammals is a longstanding hypothesis that is considered instrumental for the evolution of endothermy, a potential key innovation in this successful clade. This hypothesis is primarily based on indirect anatomical inference from fossils. Here, we reconstruct the evolutionary history of rhodopsin--the vertebrate visual pigment mediating the first step in phototransduction at low-light levels--via codon-based model tests for selection, combined with gene resurrection methods that allow for the study of ancient proteins. Rhodopsin coding sequences were reconstructed for three key nodes: Amniota, Mammalia, and Theria. When expressed in vitro, all sequences generated stable visual pigments with λMAX values similar to the well-studied bovine rhodopsin. Retinal release rates of mammalian and therian ancestral rhodopsins, measured via fluorescence spectroscopy, were significantly slower than those of the amniote ancestor, indicating altered molecular function possibly related to nocturnality. Positive selection along the therian branch suggests adaptive evolution in rhodopsin concurrent with therian ecological diversification events during the Mesozoic that allowed for an exploration of the environment at varying light levels.

  15. Dim light vision--morphological and functional adaptations of the eye of the mormyrid fish, Gnathonemus petersii.

    PubMed

    Landsberger, Meik; von der Emde, Gerhard; Haverkate, Dorothee; Schuster, Stefan; Gentsch, Janina; Ulbricht, Elke; Reichenbach, Andreas; Makarov, Felix; Wagner, Hans-Joachim

    2008-01-01

    The African weakly electric fish Gnathonemus petersii is well known for its electrosensory capabilities. These animals can detect and distinguish objects through active electrolocation in complete darkness. Because of their nocturnal lifestyle, a low contribution of vision for orientation and object detection has been expected. However, as we show in this review, the retina of G. petersii is highly specialized with hundreds of rods and tens of cones grouped together in bundles in a complex way, ensheathed by a tapetum lucidum. The structure of the bundles goes beyond what would be expected if only photon catch was supposed to be increased. During daytime, the structure of these "macro-receptors" changes dramatically depending on retinomotor movements. During the day, the rods and cones are located in different compartments of the bundle, separated by a narrow canal in the form of a "bottle neck". Investigations on cell structure and neurochemistry in the retina indicate a general organization that is simpler in terms of bipolar and ganglion cell diversity than in tetrachromatic species such as goldfish, yet similar in terms of neurochemical differentiation of amacrine cells. In both respects, the inner retina of the elephantnose fish bears the greatest similarity to catfish and some deep-sea fish retinae. Neuronal circuits and bundle structure give hints of possible adaptations for contrast and/or movement detection. Behavioral experiments suggest that, in contrast to the vision specialists Lepomis gibbosus, pattern detection of G. petersii is not affected by higher spatial frequencies. A pattern of low spatial frequencies, however, was equally well detected by G. petersii and L. gibbosus. Optomotor response experiments indicate that motion vision is important for Gnathonemus, narrowing down the search for the functional specialization of the Gnathonemus retina and providing a starting point for work on multisensory integration in these fish.

  16. A neural network to improve dim-light vision? Dendritic fields of first-order interneurons in the nocturnal bee Megalopta genalis.

    PubMed

    Greiner, Birgit; Ribi, Willi A; Warrant, Eric J

    2005-11-01

    Using the combined Golgi-electron microscopy technique, we have determined the three-dimensional dendritic fields of the short visual fibres (svf 1-3) and first-order interneurons or L-fibres (L1-4) within the first optic ganglion (lamina) of the nocturnal bee Megalopta genalis. Serial cross sections have revealed that the svf type 2 branches into one adjacent neural unit (cartridge) in layer A, the most distal of the three lamina layers A, B and C. All L-fibres, except L1-a, exhibit wide lateral branching into several neighbouring cartridges. L1-b shows a dendritic field of seven cartridges in layers A and C, dendrites of L2 target 13 cartridges in layer A, L3 branches over a total of 12 cartridges in layer A and three in layer C and L4 has the largest dendritic field size of 18 cartridges in layer C. The number of cartridges reached by the respective L-fibres is distinctly greater in the nocturnal bee than in the worker honeybee and is larger than could be estimated from our previous Golgi-light microscopy study. The extreme dorso-ventrally oriented dendritic field of L4 in M. genalis may, in addition to its potential role in spatial summation, be involved in edge detection. Thus, we have shown that the amount of lateral spreading present in the lamina provides the anatomical basis for the required spatial summation. Theoretical and future physiological work should further elucidate the roles that this lateral spreading plays to improve dim-light vision in nocturnal insects.

  17. Vertebrate rhodopsin adaptation to dim light via rapid meta-II intermediate formation.

    PubMed

    Sugawara, Tohru; Imai, Hiroo; Nikaido, Masato; Imamoto, Yasushi; Okada, Norihiro

    2010-03-01

    Rhodopsin is a photoreceptive protein present in vertebrate rod photoreceptor cells, which are responsible for scotopic vision. Recent molecular studies have shown that several aquatic vertebrate species have independently acquired rhodopsin containing Asp83Asn, Glu122Gln, and Ala292Ser substitutions, causing a blue shift in the rhodopsin absorption spectra for adaptation to the blue-green photic environment in deep water. Here, we provide new evidence for the evolutionary and functional relevance of the Asp83Asn substitution. Spectroscopic and kinetic analyses of rhodopsins in six cichlid fishes from the East African Great Lakes using charge-coupled device spectrophotometer revealed that the Asp83Asn substitution accelerated the formation of meta-II, a rhodopsin intermediate crucial for activation of the G-protein transducin. Because rapid formation of meta-II likely results in effective transduction of photic signals, it is reasonable to assume that deep-water cichlid species have acquired rhodopsin containing Asn83 to adapt to dim lighting. Remarkably, rhodopsin containing Asn83 has been identified in terrestrial vertebrates such as bats, and these rhodopsin variants also exhibit accelerated meta-II formation. Our results indicated that the Asp83Asn substitution observed in a variety of animal species was acquired independently in many different lineages during vertebrate evolution for adaptation to dimly lit environments.

  18. Dim light at night increases body mass of female mice.

    PubMed

    Aubrecht, Taryn G; Jenkins, Richelle; Nelson, Randy J

    2015-05-01

    During the past century, the prevalence of light at night has increased in parallel with obesity rates. Dim light at night (dLAN) increases body mass in male mice. However, the effects of light at night on female body mass remain unspecified. Thus, female mice were exposed to a standard light/dark (LD; 16 h light at ∼150 lux/8 h dark at ∼0 lux) cycle or to light/dim light at night (dLAN; 16 h light at ∼150 lux/8 h dim light at ∼5 lux) cycles for six weeks. Females exposed to dLAN increased the rate of change in body mass compared to LD mice despite reduced total food intake during weeks five and six, suggesting that dLAN disrupted circadian rhythms resulting in deranged metabolism.

  19. Dim Light at Night Increases Body Mass of Female Mice

    PubMed Central

    Aubrecht, Taryn G.; Jenkins, Richelle; Nelson, Randy J.

    2016-01-01

    During the past century the prevalence of light at night has increased in parallel with obesity rates. Dim light at night (dLAN) increases body mass in male mice. However, the effects of light at night on female body mass remain unspecified. Thus, female mice were exposed to a standard light/dark (LD; 16h light at ~150 lux/8h dark at ~0 lux) cycle or to light/dim light at night (dLAN; 16h light at ~150 lux/8h dim light at ~5 lux) cycles for six weeks. Females exposed to dLAN increased the rate of change in body mass compared to LD mice despite reduced total food intake during weeks five and six, suggesting that dLAN disrupted circadian rhythms resulting in deranged metabolism. PMID:25431079

  20. Photic niche invasions: phylogenetic history of the dim-light foraging augochlorine bees (Halictidae).

    PubMed

    Tierney, Simon M; Sanjur, Oris; Grajales, Grethel G; Santos, Leandro M; Bermingham, Eldredge; Wcislo, William T

    2012-02-22

    Most bees rely on flowering plants and hence are diurnal foragers. From this ancestral state, dim-light foraging in bees requires significant adaptations to a new photic environment. We used DNA sequences to evaluate the phylogenetic history of the most diverse clade of Apoidea that is adapted to dim-light environments (Augochlorini: Megalopta, Megaloptidia and Megommation). The most speciose lineage, Megalopta, is distal to the remaining dim-light genera, and its closest diurnal relative (Xenochlora) is recovered as a lineage that has secondarily reverted to diurnal foraging. Tests for adaptive protein evolution indicate that long-wavelength opsin shows strong evidence of stabilizing selection, with no more than five codons (2%) under positive selection, depending on analytical procedure. In the branch leading to Megalopta, the amino acid of the single positively selected codon is conserved among ancestral Halictidae examined, and is homologous to codons known to influence molecular structure at the chromophore-binding pocket. Theoretically, such mutations can shift photopigment λ(max) sensitivity and enable visual transduction in alternate photic environments. Results are discussed in light of the available evidence on photopigment structure, morphological specialization and biogeographic distributions over geological time.

  1. Photic niche invasions: phylogenetic history of the dim-light foraging augochlorine bees (Halictidae)

    PubMed Central

    Tierney, Simon M.; Sanjur, Oris; Grajales, Grethel G.; Santos, Leandro M.; Bermingham, Eldredge; Wcislo, William T.

    2012-01-01

    Most bees rely on flowering plants and hence are diurnal foragers. From this ancestral state, dim-light foraging in bees requires significant adaptations to a new photic environment. We used DNA sequences to evaluate the phylogenetic history of the most diverse clade of Apoidea that is adapted to dim-light environments (Augochlorini: Megalopta, Megaloptidia and Megommation). The most speciose lineage, Megalopta, is distal to the remaining dim-light genera, and its closest diurnal relative (Xenochlora) is recovered as a lineage that has secondarily reverted to diurnal foraging. Tests for adaptive protein evolution indicate that long-wavelength opsin shows strong evidence of stabilizing selection, with no more than five codons (2%) under positive selection, depending on analytical procedure. In the branch leading to Megalopta, the amino acid of the single positively selected codon is conserved among ancestral Halictidae examined, and is homologous to codons known to influence molecular structure at the chromophore-binding pocket. Theoretically, such mutations can shift photopigment λmax sensitivity and enable visual transduction in alternate photic environments. Results are discussed in light of the available evidence on photopigment structure, morphological specialization and biogeographic distributions over geological time. PMID:21795273

  2. Living in the dark does not mean a blind life: bird and mammal visual communication in dim light.

    PubMed

    Penteriani, Vincenzo; Delgado, María Del Mar

    2017-04-05

    For many years, it was believed that bird and mammal communication 'in the dark of the night' relied exclusively on vocal and chemical signalling. However, in recent decades, several case studies have conveyed the idea that the nocturnal world is rich in visual information. Clearly, a visual signal needs a source of light to work, but diurnal light (twilight included, i.e. any light directly dependent on the sun) is not the only source of luminosity on this planet. Actually, moonlight represents a powerful source of illumination that cannot be neglected from the perspective of visual communication. White patches of feathers and fur on a dark background have the potential to be used to communicate with conspecifics and heterospecifics in dim light across different contexts and for a variety of reasons. Here: (i) we review current knowledge on visual signalling in crepuscular and nocturnal birds and mammals; and (ii) we also present some possible cases of birds and mammals that, due to the characteristics of their feather and fur coloration pattern, might use visual signals in dim light. Visual signalling in nocturnal animals is still an emerging field and, to date, it has received less attention than many other means of communication, including visual communication under daylight. For this reason, many questions remain unanswered and, sometimes, even unasked.This article is part of the themed issue 'Vision in dim light'.

  3. Bumblebees Perform Well-Controlled Landings in Dim Light

    PubMed Central

    Reber, Therese; Dacke, Marie; Warrant, Eric; Baird, Emily

    2016-01-01

    To make a smooth touchdown when landing, an insect must be able to reliably control its approach speed as well as its body and leg position—behaviors that are thought to be regulated primarily by visual information. Bumblebees forage and land under a broad range of light intensities and while their behavior during the final moments of landing has been described in detail in bright light, little is known about how this is affected by decreasing light intensity. Here, we investigate this by characterizing the performance of bumblebees, B. terrestris, landing on a flat platform at two different orientations (horizontal and vertical) and at four different light intensities (ranging from 600 lx down to 19 lx). As light intensity decreased, the bees modified their body position and the distance at which they extended their legs, suggesting that the control of landing in these insects is visually mediated. Nevertheless, the effect of light intensity was small and the landings were still well controlled, even in the dimmest light. We suggest that the changes in landing behavior that occurred in dim light might represent adaptations that allow the bees to perform smooth landings across the broad range of light intensities at which they are active. PMID:27683546

  4. Behavioural environments and niche construction: the evolution of dim-light foraging in bees.

    PubMed

    Wcislo, William T; Tierney, Simon M

    2009-02-01

    Most bees forage for floral resources during the day, but temporal patterns of foraging activity vary extensively, and foraging in dim-light environments has evolved repeatedly. Facultative dim-light foraging behaviour is known in five of nine families of bees, while obligate behaviour is known in four families and evolved independently at least 19 times. The light intensity under which bees forage varies by a factor of 10(8), and therefore the evolution of dim-light foraging represents the invasion of a new, extreme niche. The repeated evolution of dim-light foraging behaviour in bees allows tests of the hypothesis that behaviour acts as an evolutionary pacemaker. With the exception of one species of Apis, facultative dim-light foragers show no external structural traits that are thought to enable visually mediated flight behaviour in low-light environments. By contrast, most obligate dim-light foragers show a suite of convergent optical traits such as enlarged ocelli and compound eyes. In one intensively studied species (Megalopta genalis) these optical changes are associated with neurobiological changes to enhance photon capture. The available ecological evidence suggests that an escape from competition for pollen and nectar resources and avoidance of natural enemies are driving factors in the evolution of obligate dim-light foraging.

  5. Body size limits dim-light foraging activity in stingless bees (Apidae: Meliponini).

    PubMed

    Streinzer, Martin; Huber, Werner; Spaethe, Johannes

    2016-10-01

    Stingless bees constitute a species-rich tribe of tropical and subtropical eusocial Apidae that act as important pollinators for flowering plants. Many foraging tasks rely on vision, e.g. spatial orientation and detection of food sources and nest entrances. Meliponini workers are usually small, which sets limits on eye morphology and thus quality of vision. Limitations are expected both on acuity, and thus on the ability to detect objects from a distance, as well as on sensitivity, and thus on the foraging time window at dusk and dawn. In this study, we determined light intensity thresholds for flight under dim light conditions in eight stingless bee species in relation to body size in a Neotropical lowland rainforest. Species varied in body size (0.8-1.7 mm thorax-width), and we found a strong negative correlation with light intensity thresholds (0.1-79 lx). Further, we measured eye size, ocelli diameter, ommatidia number, and facet diameter. All parameters significantly correlated with body size. A disproportionately low light intensity threshold in the minute Trigonisca pipioli, together with a large eye parameter P eye suggests specific adaptations to circumvent the optical constraints imposed by the small body size. We discuss the implications of body size in bees on foraging behavior.

  6. Dim light at night disrupts molecular circadian rhythms and increases body weight.

    PubMed

    Fonken, Laura K; Aubrecht, Taryn G; Meléndez-Fernández, O Hecmarie; Weil, Zachary M; Nelson, Randy J

    2013-08-01

    With the exception of high latitudes, life has evolved under bright days and dark nights. Most organisms have developed endogenously driven circadian rhythms that are synchronized to this daily light/dark cycle. In recent years, humans have shifted away from the naturally occurring solar light cycle in favor of artificial and sometimes irregular light schedules produced by electric lighting. Exposure to unnatural light cycles is increasingly associated with obesity and metabolic syndrome; however, the means by which environmental lighting alters metabolism are poorly understood. Thus, we exposed mice to dim light at night and investigated changes in the circadian system and metabolism. Here we report that exposure to ecologically relevant levels of dim (5 lux) light at night altered core circadian clock rhythms in the hypothalamus at both the gene and protein level. Circadian rhythms in clock expression persisted during light at night; however, the amplitude of Per1 and Per2 rhythms was attenuated in the hypothalamus. Circadian oscillations were also altered in peripheral tissues critical for metabolic regulation. Exposure to dimly illuminated, as compared to dark, nights decreased the rhythmic expression in all but one of the core circadian clock genes assessed in the liver. Additionally, mice exposed to dim light at night attenuated Rev-Erb expression in the liver and adipose tissue. Changes in the circadian clock were associated with temporal alterations in feeding behavior and increased weight gain. These results are significant because they provide evidence that mild changes in environmental lighting can alter circadian and metabolic function. Detailed analysis of temporal changes induced by nighttime light exposure may provide insight into the onset and progression of obesity and metabolic syndrome, as well as other disorders involving sleep and circadian rhythm disruption.

  7. Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3−/− mice, but not wildtype mice

    PubMed Central

    Martynhak, Bruno Jacson; Hogben, Alexandra L.; Zanos, Panos; Georgiou, Polymnia; Andreatini, Roberto; Kitchen, Ian; Archer, Simon N.; von Schantz, Malcolm; Bailey, Alexis; van der Veen, Daan R.

    2017-01-01

    Industrialisation greatly increased human night-time exposure to artificial light, which in animal models is a known cause of depressive phenotypes. Whilst many of these phenotypes are ‘direct’ effects of light on affect, an ‘indirect’ pathway via altered sleep-wake timing has been suggested. We have previously shown that the Period3 gene, which forms part of the biological clock, is associated with altered sleep-wake patterns in response to light. Here, we show that both wild-type and Per3−/− mice showed elevated levels of circulating corticosterone and increased hippocampal Bdnf expression after 3 weeks of exposure to dim light at night, but only mice deficient for the PERIOD3 protein (Per3−/−) exhibited a transient anhedonia-like phenotype, observed as reduced sucrose preference, in weeks 2–3 of dim light at night, whereas WT mice did not. Per3−/− mice also exhibited a significantly smaller delay in behavioural timing than WT mice during weeks 1, 2 and 4 of dim light at night exposure. When treated with imipramine, neither Per3−/− nor WT mice exhibited an anhedonia-like phenotype, and neither genotypes exhibited a delay in behavioural timing in responses to dLAN. While the association between both Per3−/− phenotypes remains unclear, both are alleviated by imipramine treatment during dim night-time light. PMID:28071711

  8. Invasion of Ancestral Mammals into Dim-light Environments Inferred from Adaptive Evolution of the Phototransduction Genes

    PubMed Central

    Wu, Yonghua; Wang, Haifeng; Hadly, Elizabeth A.

    2017-01-01

    Nocturnality is a key evolutionary innovation of mammals that enables mammals to occupy relatively empty nocturnal niches. Invasion of ancestral mammals into nocturnality has long been inferred from the phylogenetic relationships of crown Mammalia, which is primarily nocturnal, and crown Reptilia, which is primarily diurnal, although molecular evidence for this is lacking. Here we used phylogenetic analyses of the vision genes involved in the phototransduction pathway to predict the diel activity patterns of ancestral mammals and reptiles. Our results demonstrated that the common ancestor of the extant Mammalia was dominated by positive selection for dim-light vision, supporting the predominate nocturnality of the ancestral mammals. Further analyses showed that the nocturnality of the ancestral mammals was probably derived from the predominate diurnality of the ancestral amniotes, which featured strong positive selection for bright-light vision. Like the ancestral amniotes, the common ancestor of the extant reptiles and various taxa in Squamata, one of the main competitors of the temporal niches of the ancestral mammals, were found to be predominate diurnality as well. Despite this relatively apparent temporal niche partitioning between ancestral mammals and the relevant reptiles, our results suggested partial overlap of their temporal niches during crepuscular periods. PMID:28425474

  9. Home Circadian Phase Assessments with Measures of Compliance Yield Accurate Dim Light Melatonin Onsets

    PubMed Central

    Burgess, Helen J.; Wyatt, James K.; Park, Margaret; Fogg, Louis F.

    2015-01-01

    Study Objectives: There is a need for the accurate assessment of circadian phase outside of the clinic/laboratory, particularly with the gold standard dim light melatonin onset (DLMO). We tested a novel kit designed to assist in saliva sampling at home for later determination of the DLMO. The home kit includes objective measures of compliance to the requirements for dim light and half-hourly saliva sampling. Design: Participants were randomized to one of two 10-day protocols. Each protocol consisted of two back-to-back home and laboratory phase assessments in counterbalanced order, separated by a 5-day break. Setting: Laboratory or participants' homes. Participants: Thirty-five healthy adults, age 21–62 y. Interventions: N/A. Measurements and Results: Most participants received at least one 30-sec epoch of light > 50 lux during the home phase assessments (average light intensity 4.5 lux), but on average for < 9 min of the required 8.5 h. Most participants collected every saliva sample within 5 min of the scheduled time. Ninety-two percent of home DLMOs were not affected by light > 50 lux or sampling errors. There was no significant difference between the home and laboratory DLMOs (P > 0.05); on average the home DLMOs occurred 9.6 min before the laboratory DLMOs. The home DLMOs were highly correlated with the laboratory DLMOs (r = 0.91, P < 0.001). Conclusions: Participants were reasonably compliant to the home phase assessment procedures. The good agreement between the home and laboratory dim light melatonin onsets (DLMOs) demonstrates that including objective measures of light exposure and sample timing during home saliva sampling can lead to accurate home DLMOs. Clinical Trial Registration: Circadian Phase Assessments at Home, http://clinicaltrials.gov/show/NCT01487252, NCT01487252. Citation: Burgess HJ, Wyatt JK, Park M, Fogg LF. Home circadian phase assessments with measures of compliance yield accurate dim light melatonin onsets. SLEEP 2015;38(6):889–897

  10. Nighttime dim light exposure alters the responses of the circadian system.

    PubMed

    Shuboni, D; Yan, L

    2010-11-10

    The daily light dark cycle is the most salient entraining factor for the circadian system. However, in modern society, darkness at night is vanishing as light pollution steadily increases. The impact of brighter nights on wild life ecology and human physiology is just now being recognized. In the present study, we tested the possible detrimental effects of dim light exposure on the regulation of circadian rhythms, using CD1 mice housed in light/dim light (LdimL, 300 lux:20 lux) or light/dark (LD, 300 lux:1 lux) conditions. We first examined the expression of clock genes in the suprachiasmatic nucleus (SCN), the locus of the principal brain clock, in the animals of the LD and LdimL groups. Under the entrained condition, there was no difference in PER1 peak expression between the two groups, but at the trough of the PER 1 rhythm, there was an increase in PER1 in the LdimL group, indicating a decrease in the amplitude of the PER1 rhythm. After a brief light exposure (30 min, 300 lux) at night, the light-induced expression of mPer1 and mPer2 genes was attenuated in the SCN of LdimL group. Next, we examined the behavioral rhythms by monitoring wheel-running activity to determine whether the altered responses in the SCN of LdimL group have behavioral consequence. Compared to the LD controls, the LdimL group showed increased daytime activity. After being released into constant darkness, the LdimL group displayed shorter free-running periods. Furthermore, following the light exposure, the phase shifting responses were smaller in the LdimL group. The results indicate that nighttime dim light exposure can cause functional changes of the circadian system, and suggest that altered circadian function could be one of the mechanisms underlying the adverse effects of light pollution on wild life ecology and human physiology. Copyright © 2010 IBRO. Published by Elsevier Ltd. All rights reserved.

  11. Exposure to dim light at night during early development increases adult anxiety-like responses.

    PubMed

    Borniger, Jeremy C; McHenry, Zachary D; Abi Salloum, Bachir A; Nelson, Randy J

    2014-06-22

    Early experiences produce effects that may persist throughout life. Therefore, to understand adult phenotype, it is important to investigate the role of early environmental stimuli in adult behavior and health. Artificial light at night (LAN) is an increasingly common phenomenon throughout the world. However, animals, including humans, evolved under dark night conditions. Many studies have revealed affective, immune, and metabolic alterations provoked by aberrant light exposure and subsequent circadian disruption. Pups are receptive to entraining cues from the mother and then light early during development, raising the possibility that the early life light environment may influence subsequent behavior. Thus, to investigate potential influences of early life exposure to LAN on adult phenotype, we exposed mice to dim (~5 lux; full spectrum white light) or dark (~0 lux) nights pre- and/or postnatally. After weaning at 3 weeks of age, all mice were maintained in dark nights until adulthood (9 weeks of age) when behavior was assessed. Mice exposed to dim light in early life increased anxiety-like behavior and fearful responses on the elevated plus maze and passive avoidance tests. These mice also displayed reduced growth rates, which ultimately normalized during adolescence. mRNA expression of brain derived neurotrophic factor (BDNF), a neurotrophin previously linked to early life environment and adult phenotype, was not altered in the prefrontal cortex or hippocampus by early life LAN exposure. Serum corticosterone concentrations were similar between groups at weaning, suggesting that early life LAN does not elicit a long-term physiologic stress response. Dim light exposure did not influence behavior on the open field, novel object, sucrose anhedonia, or forced swim tests. Our data highlight the potential deleterious consequences of low levels of light during early life to development and subsequent behavior. Whether these changes are due to altered maternal behavior

  12. Altered vision destabilizes gait in older persons.

    PubMed

    Helbostad, Jorunn L; Vereijken, Beatrix; Hesseberg, Karin; Sletvold, Olav

    2009-08-01

    This study assessed the effects of dim light and four experimentally induced changes in vision on gait speed and footfall and trunk parameters in older persons walking on level ground. Using a quasi-experimental design, gait characteristics were assessed in full light, dim light, and in dim light combined with manipulations resulting in reduced depth vision, double vision, blurred vision, and tunnel vision, respectively. A convenience sample of 24 home-dwelling older women and men (mean age 78.5 years, SD 3.4) with normal vision for their age and able to walk at least 10 m without assistance participated. Outcome measures were gait speed and spatial and temporal parameters of footfall and trunk acceleration, derived from an electronic gait mat and accelerometers. Dim light alone had no effect. Vision manipulations combined with dim light had effect on most footfall parameters but few trunk parameters. The largest effects were found regarding double and tunnel vision. Men increased and women decreased gait speed following manipulations (p=0.017), with gender differences also in stride velocity variability (p=0.017) and inter-stride medio-lateral trunk acceleration variability (p=0.014). Gender effects were related to differences in body height and physical functioning. Results indicate that visual problems lead to a more cautious and unstable gait pattern even under relatively simple conditions. This points to the importance of assessing vision in older persons and correcting visual impairments where possible.

  13. Assessing the Dim Light Melatonin Onset in Adults with Autism Spectrum Disorder and No Comorbid Intellectual Disability

    ERIC Educational Resources Information Center

    Baker, Emma K.; Richdale, Amanda L.; Hazi, Agnes; Prendergast, Luke A.

    2017-01-01

    This study assessed melatonin levels and the dim light melatonin onset (DLMO) in adults with Autism Spectrum Disorder (ASD) and also investigated the relationships between melatonin and objectively measured sleep parameters. Sixteen adults with ASD (ASD-Only), 12 adults with ASD medicated for comorbid diagnoses of anxiety and/or depression…

  14. Parental Exposure to Dim Light at Night Prior to Mating Alters Offspring Adaptive Immunity

    PubMed Central

    Cissé, Yasmine M.; Russart, Kathryn L.G.; Nelson, Randy J.

    2017-01-01

    Exposure to dim light at night (dLAN) disrupts natural light/dark cycles and impairs endogenous circadian rhythms necessary to maintain optimal biological function, including the endocrine and immune systems. We have previously demonstrated that white dLAN compromises innate and cell mediated immune responses in adult Siberian hamsters (Phodopus sungorus). We hypothesized that dLAN has transgenerational influences on immune function. Adult male and female Siberian hamsters were exposed to either dark nights (DARK) or dLAN (~5 lux) for 9 weeks, then paired in full factorial design, mated, and thereafter housed under dark nights. Offspring were gestated and reared in dark nights, then tested as adults for cell-mediated and humoral immunity. Maternal exposure to dLAN dampened delayed type hypersensitivity (DTH) responses in male offspring. Maternal and paternal exposure to dLAN reduced DTH responses in female offspring. IgG antibodies to a novel antigen were elevated in offspring of dams exposed to dLAN. Paternal exposure to dLAN decreased splenic endocrine receptor expression and global methylation in a parental sex-specific manner. Together, these data suggest that exposure to dLAN has transgenerational effects on endocrine-immune function that may be mediated by global alterations in the epigenetic landscape of immune tissues. PMID:28361901

  15. Home dim light melatonin onsets with measures of compliance in delayed sleep phase disorder.

    PubMed

    Burgess, Helen J; Park, Margaret; Wyatt, James K; Fogg, Louis F

    2016-06-01

    The dim light melatonin onset (DLMO) assists with the diagnosis and treatment of circadian rhythm sleep disorders. Home DLMOs are attractive for cost savings and convenience, but can be confounded by home lighting and sample timing errors. We developed a home saliva collection kit with objective measures of light exposure and sample timing. We report on our first test of the kit in a clinical population. Thirty-two participants with delayed sleep phase disorder (DSPD; 17 women, aged 18-52 years) participated in two back-to-back home and laboratory phase assessments. Most participants (66%) received at least one 30-s epoch of light >50 lux during the home phase assessments, but for only 1.5% of the time. Most participants (56%) collected every saliva sample within 5 min of the scheduled time. Eighty-three per cent of home DLMOs were not affected by light or sampling errors. The home DLMOs occurred, on average, 10.2 min before the laboratory DLMOs, and were correlated highly with the laboratory DLMOs (r = 0.93, P < 0.001). These results indicate that home saliva sampling with objective measures of light exposure and sample timing, can assist in identifying accurate home DLMOs. © 2016 European Sleep Research Society.

  16. Time-dependent effects of dim light at night on re-entrainment and masking of hamster activity rhythms.

    PubMed

    Frank, David W; Evans, Jennifer A; Gorman, Michael R

    2010-04-01

    Bright light has been established as the most ubiquitous environmental cue that entrains circadian timing systems under natural conditions. Light equivalent in intensity to moonlight (<1 lux), however, also strongly modulates circadian function in a number of entrainment paradigms. For example, compared to completely dark nights, dim nighttime illumination accelerated re-entrainment of hamster activity rhythms to 4-hour phase advances and delays of an otherwise standard laboratory photocycle. The purpose of this study was to determine if a sensitive period existed in the night during which dim illumination had a robust influence on speed of re-entrainment. Male Siberian hamsters were either exposed to dim light throughout the night, for half of the night, or not at all. Compared to dark nights, dim illumination throughout the entire night decreased by 29% the time for the midpoint of the active phase to re-entrain to a 4-hour phase advance and by 26% for a 4-hour delay. Acceleration of advances and delays were also achieved with 5 hours of dim light per night, but effects depended on whether dim light was present in the first half, second half, or first and last quarters of the night. Both during phase shifting and steady-state entrainment, partially lit nights also produced strong positive and negative masking effects, as well as entrainment aftereffects in constant darkness. Thus, even in the presence of a strong zeitgeber, light that might be encountered under a natural nighttime sky potently modulates the circadian timing system of hamsters.

  17. Effects of artificial dawn on subjective ratings of sleep inertia and dim light melatonin onset.

    PubMed

    Giménez, Marina C; Hessels, Martijn; van de Werken, Maan; de Vries, Bonnie; Beersma, Domien G M; Gordijn, Marijke C M

    2010-07-01

    The timing of work and social requirements has a negative impact on performance and well-being of a significant proportion of the population in our modern society due to a phenomenon known as social jetlag. During workdays, in the early morning, late chronotypes, in particular, suffer from a combination of a nonoptimal circadian phase and sleep deprivation. Sleep inertia, a transient period of lowered arousal after awakening, therefore, becomes more severe. In the present home study, the authors tested whether the use of an alarm clock with artificial dawn could reduce complaints of sleep inertia in people having difficulties in waking up early. The authors also examined whether these improvements were accompanied by a shift in the melatonin rhythm. Two studies were performed: Study 1: three conditions (0, 50, and 250 lux) and Study 2: two conditions (0 lux and self-selected dawn-light intensity). Each condition lasted 2 weeks. In both studies, the use of the artificial dawn resulted in a significant reduction of sleep inertia complaints. However, no significant shift in the onset of melatonin was observed after 2 weeks of using the artificial dawn of 250 lux or 50 lux compared to the control condition. A multilevel analysis revealed that only the presence of the artificial dawn, rather than shift in the dim light melatonin onset or timing of sleep offset, is related to the observed reduction of sleep inertia complaints. Mechanisms other than shift of circadian rhythms are needed to explain the positive results on sleep inertia of waking up with a dawn signal.

  18. A design of LED adaptive dimming lighting system based on incremental PID controller

    NASA Astrophysics Data System (ADS)

    He, Xiangyan; Xiao, Zexin; He, Shaojia

    2010-11-01

    As a new generation energy-saving lighting source, LED is applied widely in various technology and industry fields. The requirement of its adaptive lighting technology is more and more rigorous, especially in the automatic on-line detecting system. In this paper, a closed loop feedback LED adaptive dimming lighting system based on incremental PID controller is designed, which consists of MEGA16 chip as a Micro-controller Unit (MCU), the ambient light sensor BH1750 chip with Inter-Integrated Circuit (I2C), and constant-current driving circuit. A given value of light intensity required for the on-line detecting environment need to be saved to the register of MCU. The optical intensity, detected by BH1750 chip in real time, is converted to digital signal by AD converter of the BH1750 chip, and then transmitted to MEGA16 chip through I2C serial bus. Since the variation law of light intensity in the on-line detecting environment is usually not easy to be established, incremental Proportional-Integral-Differential (PID) algorithm is applied in this system. Control variable obtained by the incremental PID determines duty cycle of Pulse-Width Modulation (PWM). Consequently, LED's forward current is adjusted by PWM, and the luminous intensity of the detection environment is stabilized by self-adaptation. The coefficients of incremental PID are obtained respectively after experiments. Compared with the traditional LED dimming system, it has advantages of anti-interference, simple construction, fast response, and high stability by the use of incremental PID algorithm and BH1750 chip with I2C serial bus. Therefore, it is suitable for the adaptive on-line detecting applications.

  19. Dim light at night disrupts the short-day response in Siberian hamsters.

    PubMed

    Ikeno, Tomoko; Weil, Zachary M; Nelson, Randy J

    2014-02-01

    Photoperiodic regulation of physiology, morphology, and behavior is crucial for many animals to survive seasonally variable conditions unfavorable for reproduction and survival. The photoperiodic response in mammals is mediated by nocturnal secretion of melatonin under the control of a circadian clock. However, artificial light at night caused by recent urbanization may disrupt the circadian clock, as well as the photoperiodic response by blunting melatonin secretion. Here we examined the effect of dim light at night (dLAN) (5lux of light during the dark phase) on locomotor activity rhythms and short-day regulation of reproduction, body mass, pelage properties, and immune responses of male Siberian hamsters. Short-day animals reduced gonadal and body mass, decreased spermatid nuclei and sperm numbers, molted to a whiter pelage, and increased pelage density compared to long-day animals. However, animals that experienced short days with dLAN did not show these short-day responses. Moreover, short-day specific immune responses were altered in dLAN conditions. The nocturnal activity pattern was blunted in dLAN hamsters, consistent with the observation that dLAN changed expression of the circadian clock gene, Period1. In addition, we demonstrated that expression levels of genes implicated in the photoperiodic response, Mel-1a melatonin receptor, Eyes absent 3, thyroid stimulating hormone receptor, gonadotropin-releasing hormone, and gonadotropin-inhibitory hormone, were higher in dLAN animals than those in short-day animals. These results suggest that dLAN disturbs the circadian clock function and affects the molecular mechanisms of the photoperiodic response.

  20. Adaptations for nocturnal vision in insect apposition eyes.

    PubMed

    Greiner, Birgit

    2006-01-01

    Due to our own preference for bright light, we tend to forget that many insects are active in very dim light. Nocturnal insects possess in general superposition compound eyes. This eye design is truly optimized for dim light as photons can be gathered through large apertures comprised of hundreds of lenses. In apposition eyes, on the other hand, the aperture consists of a single lens resulting in a poor photon catch and unreliable vision in dim light. Apposition eyes are therefore typically found in day-active insects. Some nocturnal insects have nevertheless managed the transition to a strictly nocturnal lifestyle while retaining their highly unsuitable apposition eye design. Large lenses and wide photoreceptors enhance the sensitivity of nocturnal apposition eyes. However, as the gain of these optical adaptations is limited and not sufficient for vision in dim light, additional neural adaptations in the form of spatial and temporal summation are necessary.

  1. Reading performance of monofocal pseudophakic patients with and without glasses under normal and dim light conditions.

    PubMed

    Radner, Wolfgang; Radner, Stephan; Raunig, Valerian; Diendorfer, Gabriela

    2014-03-01

    To evaluate reading performance of patients with monofocal intraocular lenses (IOLs) (Acrysof SN60WF) with or without reading glasses under bright and dim light conditions. Austrian Academy of Ophthalmology, Vienna, Austria. Evaluation of a diagnostic test or technology. In pseudophakic patients, the spherical refractive error was limited to between +0.50 diopter (D) and -0.75 D with astigmatism of 0.75 D (mean spherical equivalent: right eye, -0.08 ± 0.43 [SD]; left eye, -0.15 ± 0.35). Near addition was +2.75 D. Reading performance was assessed binocularly with or without reading glasses at an illumination of 100 candelas (cd)/m(2) and 4 cd/m(2) using the Radner Reading Charts. In the 25 patients evaluated, binocularly, the mean corrected distance visual acuity was -0.07 ± 0.06 logMAR and the mean uncorrected distance visual acuity was 0.01 ± 0.11 logMAR. The mean reading acuity with reading glasses was 0.02 ± 0.10 logRAD at 100 cd/m(2) and 0.12 ± 0.14 logRAD at 4 cd/m(2). Without reading glasses, it was 0.44 ± 0.13 logRAD and 0.56 ± 0.16 logRAD, respectively (P < .05). Without reading glasses and at 100 cd/m(2), 40% of patients read 0.4 logRAD at more than 80 words per minute (wpm), 68% exceeded this limit at 0.5 logRAD, and 92% exceeded it at 0.6 logRAD. The mean reading speed at 0.5 logRAD was 134.76 ± 48.22 wpm; with reading glasses it was 167.65 ± 32.77 wpm (P < .05). A considerable percentage of patients with monofocal IOLs read newspaper print size without glasses under good light conditions. Copyright © 2014 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  2. Nocturnal colour vision in geckos.

    PubMed Central

    Roth, Lina S V; Kelber, Almut

    2004-01-01

    Nocturnal animals are said to sacrifice colour vision in favour of increased absolute sensitivity. This is true for most vertebrates that possess a dual retina with a single type of rod for colour-blind night vision and multiple types of cone for diurnal colour vision. However, among the nocturnal vertebrates, geckos are unusual because they have no rods but three cone types. Here, we show that geckos use their cones for colour vision in dim light. Two specimens of the nocturnal helmet gecko Tarentola (formerly Geckonia) chazaliae were able to discriminate blue from grey patterns by colour alone. Experiments were performed at 0.002 cd m(-2), a light intensity similar to dim moonlight. We conclude that nocturnal geckos can use cone-based colour vision at very dim light levels when humans rely on colour-blind rod vision. PMID:15801611

  3. Nocturnal colour vision in geckos.

    PubMed

    Roth, Lina S V; Kelber, Almut

    2004-12-07

    Nocturnal animals are said to sacrifice colour vision in favour of increased absolute sensitivity. This is true for most vertebrates that possess a dual retina with a single type of rod for colour-blind night vision and multiple types of cone for diurnal colour vision. However, among the nocturnal vertebrates, geckos are unusual because they have no rods but three cone types. Here, we show that geckos use their cones for colour vision in dim light. Two specimens of the nocturnal helmet gecko Tarentola (formerly Geckonia) chazaliae were able to discriminate blue from grey patterns by colour alone. Experiments were performed at 0.002 cd m(-2), a light intensity similar to dim moonlight. We conclude that nocturnal geckos can use cone-based colour vision at very dim light levels when humans rely on colour-blind rod vision.

  4. Acute dim light at night increases body mass, alters metabolism, and shifts core body temperature circadian rhythms.

    PubMed

    Borniger, Jeremy C; Maurya, Santosh K; Periasamy, Muthu; Nelson, Randy J

    2014-10-01

    The circadian system is primarily entrained by the ambient light environment and is fundamentally linked to metabolism. Mounting evidence suggests a causal relationship among aberrant light exposure, shift work, and metabolic disease. Previous research has demonstrated deleterious metabolic phenotypes elicited by chronic (>4 weeks) exposure to dim light at night (DLAN) (∼ 5 lux). However, the metabolic effects of short-term (<2 weeks) exposure to DLAN are unspecified. We hypothesized that metabolic alterations would arise in response to just 2 weeks of DLAN. Specifically, we predicted that mice exposed to dim light would gain more body mass, alter whole body metabolism, and display altered body temperature (Tb) and activity rhythms compared to mice maintained in dark nights. Our data largely support these predictions; DLAN mice gained significantly more mass, reduced whole body energy expenditure, increased carbohydrate over fat oxidation, and altered temperature circadian rhythms. Importantly, these alterations occurred despite similar activity locomotor levels (and rhythms) and total food intake between groups. Peripheral clocks are potently entrained by body temperature rhythms, and the deregulation of body temperature we observed may contribute to metabolic problems due to "internal desynchrony" between the central circadian oscillator and temperature sensitive peripheral clocks. We conclude that even relatively short-term exposure to low levels of nighttime light can influence metabolism to increase mass gain.

  5. Prediction of melatonin efficacy by pretreatment dim light melatonin onset in children with idiopathic chronic sleep onset insomnia.

    PubMed

    van der Heijden, Kristiaan B; Smits, Marcel G; van Someren, Eus J W; Boudewijn Gunning, W

    2005-06-01

    Research has shown efficacy of melatonin treatment to advance sleep-wake rhythms in insomnia. In healthy adults, direction and magnitude of the phase shift depends on the timing of administration relative to the phase position of the circadian system. Therefore, in the present study we investigated whether in children with chronic sleep onset insomnia (SOI) efficacy of melatonin treatment in the early evening could be predicted from dim light melatonin onset (DLMO), a phase marker of the circadian system. We combined data of two previously published double blind, randomized, placebo-controlled trials in 110 participants, aged 6-12 years. Sleep was actigraphically estimated, and saliva collected, at baseline and in the third week of a 4-week treatment period with 5 mg melatonin or placebo at 18:00 or 19:00 hours. Primary outcome measures were pre- to post-treatment changes in dim light melatonin onset (DeltaDLMO), sleep onset (DeltaSO), sleep latency (DeltaSL), and total sleep duration (DeltaTSD). Melatonin advanced DLMO with +1:12 h (P < 0.001), SO with +0:42 h (P = 0.004), SL decreased with 25 min (P = 0.019), and TSD did not change significantly, as compared with placebo. In the melatonin-treated group, but not in the placebo-treated group, pretreatment DLMO was significantly related to DeltaDLMO [F(1, 29) = 7.28, P = 0.012] and DeltaSO [F(1, 25) = 7.72, P = 0.010]. The time interval between treatment administration and pretreatment DLMO (INT) was only significantly related to DeltaSO [F(1,26) = 5.40, P = 0.028]. The results suggest that in children with SOI, the efficacy of early evening melatonin to advance sleep onset and endogenous melatonin onset increases the later the pretreatment DLMO is.

  6. Effects of extracellular calcium and of light adaptation on the response to dim light in honey bee drone photoreceptors.

    PubMed

    Raggenbass, M

    1983-11-01

    Light responses in honey bee drone photoreceptors were recorded with intracellular micro-electrodes in superfused slices of retina. The effects of changes in extracellular calcium on the size and the shape of the response to dim light were studied and compared with the effects of light adaptation. Dim light stimuli were used so that the amplitude of the response was linearly related to the number of the photons absorbed, the effects of voltage-dependent mechanisms were negligible and no detectable light adaptation was produced by the stimulus. Lowering the extracellular calcium concentration increased the amplitude and the duration of the response. Raising the extracellular calcium concentration produced the opposite effects. Changing the extracellular calcium concentration modified the response without altering either the linearity of the intensity--response relation or the resting membrane potential in the dark. Light adaptation decreased the amplitude and the duration of the response in a manner that could be quantitatively simulated, in the same photoreceptors, by an increase in the extracellular calcium concentration. Changing the extracellular calcium concentration, or light-adapting the preparation, modified the response without altering its early depolarizing phase. Lowering external calcium either did not affect, or slightly increased, the maximum rate of the light-induced depolarization; raising external calcium, or light-adapting the preparation, either did not affect, or slightly decreased, the maximum rate of the light-induced depolarization. The experimental data can be quantitatively described by a mathematical model with the basic assumption that calcium acts in the process of light adaptation by decreasing the mean open time of the light-activated channels.

  7. Objective measures of sleep and dim light melatonin onset in adolescents and young adults with delayed sleep phase disorder compared to healthy controls.

    PubMed

    Saxvig, Ingvild W; Wilhelmsen-Langeland, Ane; Pallesen, Ståle; Vedaa, Oystein; Nordhus, Inger H; Sørensen, Eli; Bjorvatn, Bjørn

    2013-08-01

    Delayed sleep phase disorder is characterized by a delay in the timing of the major sleep period relative to conventional norms. The sleep period itself has traditionally been described as normal. Nevertheless, it is possible that sleep regulatory mechanism disturbances associated with the disorder may affect sleep duration and/or architecture. Polysomnographic data that may shed light on the issue are scarce. Hence, the aim of this study was to examine polysomnographic measures of sleep in adolescents and young adults with delayed sleep phase disorder, and to compare findings to that of healthy controls. A second aim was to estimate dim light melatonin onset as a marker of circadian rhythm and to investigate the phase angle relationship (time interval) between dim light melatonin onset and the sleep period. Data from 54 adolescents and young adults were analysed, 35 diagnosed with delayed sleep phase disorder and 19 healthy controls. Results show delayed timing of sleep in participants with delayed sleep phase disorder, but once sleep was initiated no group differences in sleep parameters were observed. Dim light melatonin onset was delayed in participants with delayed sleep phase disorder, but no difference in phase angle was observed between the groups. In conclusion, both sleep and dim light melatonin onset were delayed in participants with delayed sleep phase disorder. The sleep period appeared to occur at the same circadian phase in both groups, and once sleep was initiated no differences in sleep parameters were observed.

  8. Why the dim light melatonin onset (DLMO) should be measured before treatment of patients with circadian rhythm sleep disorders.

    PubMed

    Keijzer, Henry; Smits, Marcel G; Duffy, Jeanne F; Curfs, Leopold M G

    2014-08-01

    Treatment of circadian rhythm sleep disorders (CRSD) may include light therapy, chronotherapy and melatonin. Exogenous melatonin is increasingly being used in patients with insomnia or CRSD. Although pharmacopoeias and the European food safety authority (EFSA) recommend administering melatonin 1-2 h before desired bedtime, several studies have shown that melatonin is not always effective if administered according to that recommendation. Crucial for optimal treatment of CRSD, melatonin and other treatments should be administered at a time related to individual circadian timing (typically assessed using the dim light melatonin onset (DLMO)). If not administered according to the individual patient's circadian timing, melatonin and other treatments may not only be ineffective, they may even result in contrary effects. Endogenous melatonin levels can be measured reliably in saliva collected at the patient's home. A clinically reliably DLMO can be calculated using a fixed threshold. Diary and polysomnographic sleep-onset time do not reliably predict DLMO or circadian timing in patients with CRSD. Knowing the patient's individual circadian timing by assessing DLMO can improve diagnosis and treatment of CRSD with melatonin as well as other therapies such as light or chronotherapy, and optimizing treatment timing will shorten the time required to achieve results.

  9. Lack of short-wavelength light during the school day delays dim light melatonin onset (DLMO) in middle school students

    PubMed Central

    Figueiro, Mariana G.; Rea, Mark S.

    2012-01-01

    OBJECTIVE Circadian timing affects sleep onset. Delayed sleep onset can reduce sleep duration in adolescents required to awake early for a fixed school schedule. The absence of short-wavelength (“blue”) morning light, which helps entrain the circadian system, can hypothetically delay sleep onset and decrease sleep duration in adolescents. The goal of this study was to investigate whether removal of short-wavelength light during the morning hours delayed the onset of melatonin in young adults. METHODS Dim light melatonin onset (DLMO) was measured in eleven 8th-grade students before and after wearing orange glasses, which removed short-wavelength light, for a five-day school week. RESULTS DLMO was significantly delayed (30 minutes) after the five-day intervention, demonstrating that short-wavelength light exposure during the day can be important for advancing circadian rhythms in students. CONCLUSIONS Lack of short-wavelength light in the morning has been shown to delay the circadian clock in controlled laboratory conditions. The results presented here are the first to show, outside laboratory conditions, that removal of short-wavelength light in the morning hours can delay DLMO in 8th-grade students. These field data, consistent with results from controlled laboratory studies, are directly relevant to lighting practice in schools. PMID:20150866

  10. Lack of short-wavelength light during the school day delays dim light melatonin onset (DLMO) in middle school students.

    PubMed

    Figueiro, Mariana G; Rea, Mark S

    2010-01-01

    Circadian timing affects sleep onset. Delayed sleep onset can reduce sleep duration in adolescents required to awake early for a fixed school schedule. The absence of short-wavelength ("blue") morning light, which helps entrain the circadian system, can hypothetically delay sleep onset and decrease sleep duration in adolescents. The goal of this study was to investigate whether removal of short-wavelength light during the morning hours delayed the onset of melatonin in young adults. Dim light melatonin onset (DLMO) was measured in eleven 8th-grade students before and after wearing orange glasses, which removed short-wavelength light, for a five-day school week. DLMO was significantly delayed (30 minutes) after the five-day intervention, demonstrating that short-wavelength light exposure during the day can be important for advancing circadian rhythms in students. Lack of short-wavelength light in the morning has been shown to delay the circadian clock in controlled laboratory conditions. The results presented here are the first to show, outside laboratory conditions, that removal of short-wavelength light in the morning hours can delay DLMO in 8th-grade students. These field data, consistent with results from controlled laboratory studies, are directly relevant to lighting practice in schools.

  11. Effect of evening exposure to bright or dim light after daytime bright light on absorption of dietary carbohydrates the following morning.

    PubMed

    Hirota, Naoko; Sone, Yoshiaki; Tokura, Hiromi

    2010-01-01

    We had previously reported on the effect of exposure to light on the human digestive system: daytime bright light exposure has a positive effect, whereas, evening bright light exposure has a negative effect on the efficiency of dietary carbohydrate absorption from the evening meal. These results prompted us to examine whether the light intensity to which subjects are exposed in the evening affects the efficiency of dietary carbohydrate absorption the following morning. In this study, subjects were exposed to either 50 lux (dim light conditions) or 2,000 lux (bright light conditions) in the evening for 9 h (from 15:00 to 24:00) after staying under bright light in the daytime (under 2,000 lux from 07:00 to 15:00). We measured unabsorbed dietary carbohydrates using the breath-hydrogen test the morning after exposure to either bright light or dim light the previous evening. Results showed that there was no significant difference between the two conditions in the amount of breath hydrogen. This indicates that evening exposure to bright or dim light after bright light exposure in the daytime has no varying effect on digestion or absorption of dietary carbohydrates in the following morning's breakfast.

  12. Preliminary evidence that light through the eyelids can suppress melatonin and phase shift dim light melatonin onset

    PubMed Central

    2012-01-01

    Background A previous study reported a method for measuring the spectral transmittance of individual human eyelids. A prototype light mask using narrow-band “green” light (λmax = 527 nm) was used to deliver light through closed eyelids in two within-subjects studies. The first study investigated whether an individual-specific light dose could suppress melatonin by 40% through the closed eyelid without disrupting sleep. The light doses were delivered at three times during the night: 1) beginning (while subjects were awake), 2) middle (during rapid eye movement (REM) sleep), and 3) end (during non-REM sleep). The second study investigated whether two individual-specific light doses expected to suppress melatonin by 30% and 60% and delivered through subjects’ closed eyelids before the time of their predicted minimum core body temperature would phase delay the timing of their dim light melatonin onset (DLMO). Findings Compared to a dark control night, light delivered through eyelids suppressed melatonin by 36% (p = 0.01) after 60-minute light exposure at the beginning, 45% (p = 0.01) at the middle, and 56% (p < 0.0001) at the end of the night. In the second study, compared to a dark control night, melatonin was suppressed by 25% (p = 0.03) and by 45% (p = 0.009) and circadian phase, as measured by DLMO, was delayed by 17 minutes (p = 0.03) and 71 minutes (ns) after 60-minute exposures to light levels 1 and 2, respectively. Conclusions These studies demonstrate that individual-specific doses of light delivered through closed eyelids can suppress melatonin and phase shift DLMO and may be used to treat circadian sleep disorders. PMID:22564396

  13. Preliminary evidence that light through the eyelids can suppress melatonin and phase shift dim light melatonin onset.

    PubMed

    Figueiro, Mariana G; Rea, Mark S

    2012-05-07

    A previous study reported a method for measuring the spectral transmittance of individual human eyelids. A prototype light mask using narrow-band "green" light (λmax = 527 nm) was used to deliver light through closed eyelids in two within-subjects studies. The first study investigated whether an individual-specific light dose could suppress melatonin by 40% through the closed eyelid without disrupting sleep. The light doses were delivered at three times during the night: 1) beginning (while subjects were awake), 2) middle (during rapid eye movement (REM) sleep), and 3) end (during non-REM sleep). The second study investigated whether two individual-specific light doses expected to suppress melatonin by 30% and 60% and delivered through subjects' closed eyelids before the time of their predicted minimum core body temperature would phase delay the timing of their dim light melatonin onset (DLMO). Compared to a dark control night, light delivered through eyelids suppressed melatonin by 36% (p = 0.01) after 60-minute light exposure at the beginning, 45% (p = 0.01) at the middle, and 56% (p < 0.0001) at the end of the night. In the second study, compared to a dark control night, melatonin was suppressed by 25% (p = 0.03) and by 45% (p = 0.009) and circadian phase, as measured by DLMO, was delayed by 17 minutes (p = 0.03) and 71 minutes (ns) after 60-minute exposures to light levels 1 and 2, respectively. These studies demonstrate that individual-specific doses of light delivered through closed eyelids can suppress melatonin and phase shift DLMO and may be used to treat circadian sleep disorders.

  14. Dim-light photoreceptor of chub mackerel Scomber japonicus and the photoresponse upon illumination with LEDs of different wavelengths.

    PubMed

    Jang, Jun-Chul; Choi, Mi-Jin; Yang, Yong-Soo; Lee, Hyung-Been; Yu, Young-Moon; Kim, Jong-Myoung

    2016-06-01

    To study the absorption characteristics of rhodopsin, a dim-light photoreceptor, in chub mackerel (Scomber japonicus) and the relationship between light wavelengths on the photoresponse, the rod opsin gene was cloned into an expression vector, pMT4. Recombinant opsin was transiently expressed in COS-1 cells and reconstituted with 11-cis-retinal. Cells containing the regenerated rhodopsin were solubilized and subjected to UV/Vis spectroscopic analysis in the dark and upon illumination. Difference spectra from the lysates indicated an absorption maximum of mackerel rhodopsin around 500 nm. Four types of light-emitting diode (LED) modules with different wavelengths (red, peak 627 nm; cyan, 505 nm; blue, 442 nm; white, 447 + 560 nm) were constructed to examine their effects on the photoresponse in chub mackerel. Behavioral responses of the mackerels, including speed and frequencies acclimated in the dark and upon LED illumination, were analyzed using an underwater acoustic camera. Compared to an average speed of 22.25 ± 1.57 cm/s of mackerel movement in the dark, speed increased to 22.97 ± 0.29, 24.66 ± 1.06, 26.28 ± 2.28, and 25.19 ± 1.91 cm/s upon exposure to red, blue, cyan, and white LEDs, respectively. There were increases of 103.48 ± 1.58, 109.37 ± 5.29, 118.48 ± 10.82, and 109.43 ± 3.92 %, respectively, in the relative speed of the fishes upon illumination with red, blue, cyan, and white LEDs compared with that in the dark (set at 100 %). Similar rate of wavelength-dependent responses was observed in a frequency analysis. These results indicate that an LED emitting a peak wavelength close to an absorption maximum of rhodopsin is more effective at eliciting a response to light.

  15. Dim light at night interferes with the development of the short-day phenotype and impairs cell-mediated immunity in Siberian hamsters (Phodopus sungorus).

    PubMed

    Aubrecht, Taryn G; Weil, Zachary M; Nelson, Randy J

    2014-10-01

    Winter is a challenging time to survive and breed outside of the tropics. Animals use day length (photoperiod) to regulate seasonally appropriate adaptations in anticipation of challenging winter conditions. The net result of these photoperiod-mediated adjustments is enhanced immune function and increased survival. Thus, the ability to discriminate day length information is critical for survival and reproduction in small animals. However, during the past century, urban and suburban development has rapidly expanded and filled the night sky with light from various sources, obscuring crucial light-dark signals, which alters physiological interpretation of day lengths. Furthermore, reduced space, increased proximity to people, and the presence of light at night may act as stressors for small animals. Whereas acute stressors typically enhance immune responses, chronic exposure to stressors often impairs immune responses. Therefore, we hypothesized that the combination of dim light at night and chronic stress interferes with enhanced cell-mediated immunity observed during short days. Siberian hamsters (Phodopus sungorus) were assigned to short or long days with dark nights (0 lux) or dim (5 lux) light at night for 10 weeks. Following 2 weeks of chronic restraint (6 hr/day), a model of chronic stress, delayed type hypersensitivity (DTH) responses were assessed. Both dim light at night and restraint reduced the DTH response. Dim light at night during long nights produced an intermediate short day phenotype. These results suggest the constant presence of light at night could negatively affect survival of photoperiodic rodents by disrupting the timing of breeding and immune responses. © 2014 Wiley Periodicals, Inc.

  16. Night Vision Manual for the Flight Surgeon

    DTIC Science & Technology

    1992-08-01

    may cause night blindness are glaucoma, progressive cone/rod dystrophies (e.g., retinitis pigmentosa , Stargardt’s disease), drug toxicity (e.g...Alabama, July 1989. 38. Berson EL, Rabin AR, Mehaffey L. Advances in night vision twchnology: A pocketscope for patients with retinitis pigmentosa ... retinal sensitivity to dim light. Regeneration of the photopigments occurs during dark adaptation. The fully dark-adapted eye, in which photopigment

  17. Estimating the dim light melatonin onset of adolescents within a 6-h sampling window: the impact of sampling rate and threshold method

    PubMed Central

    Crowley, Stephanie J.; Suh, Christina; Molina, Thomas A.; Fogg, Louis F.; Sharkey, Katherine M.; Carskadon, Mary A.

    2016-01-01

    Objective/Background Circadian rhythm sleep-wake disorders often manifest during the adolescent years. Measurement of circadian phase such as the Dim Light Melatonin Onset (DLMO) improves diagnosis and treatment of these disorders, but financial and time costs limit the use of DLMO phase assessments in clinic. The current analysis aims to inform a cost-effective and efficient protocol to measure the DLMO in older adolescents by reducing the number of samples and total sampling duration. Patients/Methods A total of 66 healthy adolescents (26 males) aged 14.8 to 17.8 years participated in a study in which sleep was fixed for one week before they came to the laboratory for saliva collection in dim light (<20 lux). Two partial 6-h salivary melatonin profiles were derived for each participant. Both profiles began 5 h before bedtime and ended 1 h after bedtime, but one profile was derived from samples taken every 30 mins (13 samples) and the other from samples taken every 60 mins (7 samples). Three standard thresholds (first 3 melatonin values mean + 2 SDs, 3 pg/mL, and 4 pg/mL) were used to compute the DLMO. Agreement between DLMOs derived from 30-min and 60-min sampling rates was determined using a Bland-Altman analysis; agreement between sampling rate DLMOs was defined as ± 1 h. Results and Conclusions Within a 6-h sampling window, 60-min sampling provided DLMO estimates that were within ± 1 h of DLMO from 30-min sampling, but only when an absolute threshold (3 pg/mL or 4 pg/mL) was used to compute the DLMO. Future analyses should be extended to include adolescents with circadian rhythm sleep-wake disorders. PMID:27318227

  18. Estimating the dim light melatonin onset of adolescents within a 6-h sampling window: the impact of sampling rate and threshold method.

    PubMed

    Crowley, Stephanie J; Suh, Christina; Molina, Thomas A; Fogg, Louis F; Sharkey, Katherine M; Carskadon, Mary A

    2016-04-01

    Circadian rhythm sleep-wake disorders (CRSWDs) often manifest during the adolescent years. Measurement of circadian phase such as the dim light melatonin onset (DLMO) improves diagnosis and treatment of these disorders, but financial and time costs limit the use of DLMO phase assessments in clinic. The current analysis aims to inform a cost-effective and efficient protocol to measure the DLMO in older adolescents by reducing the number of samples and total sampling duration. A total of 66 healthy adolescents (26 males) aged 14.8-17.8 years participated in a study; they were required to sleep on a fixed baseline schedule for a week before which they visited the laboratory for saliva collection in dim light (<20 lux). Two partial 6-h salivary melatonin profiles were derived for each participant. Both profiles began 5 h before bedtime and ended 1 h after bedtime, but one profile was derived from samples taken every 30 min (13 samples) and the other from samples taken every 60 min (seven samples). Three standard thresholds (first three melatonin values mean + 2 SDs, 3 pg/mL, and 4 pg/mL) were used to compute the DLMO. An agreement between DLMOs derived from 30-min and 60-min sampling rates was determined using Bland-Altman analysis; agreement between the sampling rate DLMOs was defined as ± 1 h. Within a 6-h sampling window, 60-min sampling provided DLMO estimates within ± 1 h of DLMO from 30-min sampling, but only when an absolute threshold (3 or 4 pg/mL) was used to compute the DLMO. Future analyses should be extended to include adolescents with CRSWDs. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Night vision by cuttlefish enables changeable camouflage.

    PubMed

    Allen, Justine J; Mäthger, Lydia M; Buresch, Kendra C; Fetchko, Thomas; Gardner, Meg; Hanlon, Roger T

    2010-12-01

    Because visual predation occurs day and night, many predators must have good night vision. Prey therefore exhibit antipredator behaviours in very dim light. In the field, the giant Australian cuttlefish (Sepia apama) assumes camouflaged body patterns at night, each tailored to its immediate environment. However, the question of whether cuttlefish have the perceptual capability to change their camouflage at night (as they do in day) has not been addressed. In this study, we: (1) monitored the camouflage patterns of Sepia officinalis during the transition from daytime to night-time using a natural daylight cycle and (2) tested whether cuttlefish on a particular artificial substrate change their camouflage body patterns when the substrate is changed under dim light (down to starlight, 0.003 lux) in a controlled light field in a dark room setting. We found that cuttlefish camouflage patterns are indeed adaptable at night: animals responded to a change in their visual environment with the appropriate body pattern change. Whether to deceive their prey or predators, cuttlefish use their excellent night vision to perform adaptive camouflage in dim light.

  20. Inferred L/M cone opsin polymorphism of ancestral tarsiers sheds dim light on the origin of anthropoid primates

    PubMed Central

    Melin, Amanda D.; Matsushita, Yuka; Moritz, Gillian L.; Dominy, Nathaniel J.; Kawamura, Shoji

    2013-01-01

    Tarsiers are small nocturnal primates with a long history of fuelling debate on the origin and evolution of anthropoid primates. Recently, the discovery of M and L opsin genes in two sister species, Tarsius bancanus (Bornean tarsier) and Tarsius syrichta (Philippine tarsier), respectively, was interpreted as evidence of an ancestral long-to-middle (L/M) opsin polymorphism, which, in turn, suggested a diurnal or cathemeral (arrhythmic) activity pattern. This view is compatible with the hypothesis that stem tarsiers were diurnal; however, a reversion to nocturnality during the Middle Eocene, as evidenced by hyper-enlarged orbits, predates the divergence of T. bancanus and T. syrichta in the Late Miocene. Taken together, these findings suggest that some nocturnal tarsiers possessed high-acuity trichromatic vision, a concept that challenges prevailing views on the adaptive origins of the anthropoid visual system. It is, therefore, important to explore the plausibility and antiquity of trichromatic vision in the genus Tarsius. Here, we show that Sulawesi tarsiers (Tarsius tarsier), a phylogenetic out-group of Philippine and Bornean tarsiers, have an L opsin gene that is more similar to the L opsin gene of T. syrichta than to the M opsin gene of T. bancanus in non-synonymous nucleotide sequence. This result suggests that an L/M opsin polymorphism is the ancestral character state of crown tarsiers and raises the possibility that many hallmarks of the anthropoid visual system evolved under dim (mesopic) light conditions. This interpretation challenges the persistent nocturnal–diurnal dichotomy that has long informed debate on the origin of anthropoid primates. PMID:23536597

  1. Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA.

    PubMed

    Herrmann, Rolf; Heflin, Stephanie J; Hammond, Timothy; Lee, Bowa; Wang, Jing; Gainetdinov, Raul R; Caron, Marc G; Eggers, Erika D; Frishman, Laura J; McCall, Maureen A; Arshavsky, Vadim Y

    2011-10-06

    Dark and light adaptation of retinal neurons allow our vision to operate over an enormous light intensity range. Here we report a mechanism that controls the light sensitivity and operational range of rod-driven bipolar cells that mediate dim-light vision. Our data indicate that the light responses of these cells are enhanced by sustained chloride currents via GABA(C) receptor channels. This sensitizing GABAergic input is controlled by dopamine D1 receptors, with horizontal cells serving as a plausible source of GABA release. Our findings expand the role of dopamine in vision from its well-established function of suppressing rod-driven signals in bright light to enhancing the same signals under dim illumination. They further reveal a role for GABA in sensitizing the circuitry for dim-light vision, thereby complementing GABA's traditional role in providing dynamic feedforward and feedback inhibition in the retina.

  2. Delayed sleep phase syndrome: A placebo-controlled cross-over study on the effects of melatonin administered five hours before the individual dim light melatonin onset.

    PubMed

    Nagtegaal, J E; Kerkhof, G A; Smits, M G; Swart, A C; Van Der Meer, Y G

    1998-06-01

    In a double-blind placebo-controlled cross-over study, 30 patients with Delayed Sleep Phase Syndrome (DSPS) were included, of whom 25 finished the study. Melatonin 5 mg was administered during two weeks in a double-blind setting and two weeks in an open setting successively or interrupted by two week of placebo. The study's impact was assessed by measurements of the 24-h curves of endogenous melatonin production and rectal temperature (n = 14), polysomnography (n = 22), actigraphy (n = 13), sleep log (n = 22), and subjective sleep quality (n = 25). Mean dim light melatonin onset (DLMO) (+/- SD), before treatment, occurred at 23.17 hours (+/- 138 min). Melatonin was administered five hours before the individual DLMO. After treatment, the onset of the nocturnal melatonin profile was significantly advanced by approximately 1.5 hour. Body temperature trough did not advance significantly. During melatonin use, actigraphy showed a significant advance of sleep onset and polysomnography, a significant decreased sleep latency. Sleep architecture was not influenced. During melatonin treatment patients felt significantly more refreshed in the morning. These results show that analysis of DLMO of patients suffering from DSPS is important both for diagnosis and therapy. These results are discussed in terms of the biochemistry of the pineal.

  3. Ultraviolet vision may be widespread in bats

    USGS Publications Warehouse

    Gorresen, P. Marcos; Cryan, Paul; Dalton, David C.; Wolf, Sandy; Bonaccorso, Frank

    2015-01-01

    Insectivorous bats are well known for their abilities to find and pursue flying insect prey at close range using echolocation, but they also rely heavily on vision. For example, at night bats use vision to orient across landscapes, avoid large obstacles, and locate roosts. Although lacking sharp visual acuity, the eyes of bats evolved to function at very low levels of illumination. Recent evidence based on genetics, immunohistochemistry, and laboratory behavioral trials indicated that many bats can see ultraviolet light (UV), at least at illumination levels similar to or brighter than those before twilight. Despite this growing evidence for potentially widespread UV vision in bats, the prevalence of UV vision among bats remains unknown and has not been studied outside of the laboratory. We used a Y-maze to test whether wild-caught bats could see reflected UV light and whether such UV vision functions at the dim lighting conditions typically experienced by night-flying bats. Seven insectivorous species of bats, representing five genera and three families, showed a statistically significant ‘escape-toward-the-light’ behavior when placed in the Y-maze. Our results provide compelling evidence of widespread dim-light UV vision in bats.

  4. Cell ``vision'': complementary factor of protein corona in nanotoxicology

    NASA Astrophysics Data System (ADS)

    Mahmoudi, Morteza; Saeedi-Eslami, Seyyed N.; Shokrgozar, Mohammad A.; Azadmanesh, Kayhan; Hassanlou, Maryam; Kalhor, Hamid R.; Burtea, Carmen; Rothen-Rutishauser, Barbara; Laurent, Sophie; Sheibani, Sara; Vali, Hojatollah

    2012-08-01

    Engineered nanoparticles are increasingly being considered for use as biosensors, imaging agents and drug delivery vehicles. Their versatility in design and applications make them an attractive proposition for new biological and biomedical approaches. Despite the remarkable speed of development in nanoscience, relatively little is known about the interaction of nanoscale objects with living systems. In a biological fluid, proteins associate with nanoparticles, and the amount and the presentation of the proteins on their surface could lead to a different in vivo response than an uncoated particle. Here, in addition to protein adsorption, we are going to introduce concept of cell ``vision'', which would be recognized as another crucial factor that should be considered for the safe design of any type of nanoparticles that will be used in specific biomedical applications. The impact of exactly the same nanoparticles on various cells is significantly different and could not be assumed for other cells; the possible mechanisms that justify this cellular response relate to the numerous detoxification strategies that any particular cell can utilize in response to nanoparticles. The uptake and defence mechanism could be considerably different according to the cell type. Thus, what the cell ``sees'', when it is faced with nanoparticles, is most likely dependent on the cell type.Engineered nanoparticles are increasingly being considered for use as biosensors, imaging agents and drug delivery vehicles. Their versatility in design and applications make them an attractive proposition for new biological and biomedical approaches. Despite the remarkable speed of development in nanoscience, relatively little is known about the interaction of nanoscale objects with living systems. In a biological fluid, proteins associate with nanoparticles, and the amount and the presentation of the proteins on their surface could lead to a different in vivo response than an uncoated particle. Here

  5. Combined effects of exposure to dim light at night and fine particulate matter on C3H/HeNHsd mice.

    PubMed

    Hogan, Matthew K; Kovalycsik, Taylor; Sun, Qinghua; Rajagopalan, Sanjay; Nelson, Randy J

    2015-11-01

    Air and light pollution contribute to fetal abnormalities, increase prevalence of cancer, metabolic and cardiorespiratory diseases, and central nervous system (CNS) disorders. A component of air pollution, particulate matter, and the phenomenon of dim light at night (dLAN) both result in neuroinflammation, which has been implicated in several CNS disorders. The combinatorial role of these pollutants on health outcomes has not been assessed. Male C3H/HeNHsd mice, with intact melatonin production, were used to model humans exposed to circadian disruption by dLAN and contaminated environmental air. We hypothesized exposure to 2.5 μm of particulate matter (PM2.5) and dLAN (5lx) combines to upregulate neuroinflammatory cytokine expression and alter hippocampal morphology compared to mice exposed to filtered air (FA) and housed under dark nights (LD). We also hypothesized that exposure to PM2.5 and dLAN provokes anxiety-like and depressive-like responses. For four weeks, four groups of mice were simultaneously exposed to ambient concentrated PM2.5 or FA and/or dLAN or LD. Following exposure, mice underwent several behavioral assays and hippocampi were collected for qPCR and morphological analyses. Our results are generally comparable to previous PM2.5 and dLAN reports conducted on mice and implicate PM2.5 and dLAN as potential factors contributing to depression and anxiety. Short-term exposure to PM2.5 and dLAN upregulated neuroinflammatory cytokines and altered CA1 hippocampal structural changes, as well as provoked depressive-like responses (anhedonia). However, combined, PM2.5 and dLAN exposure did not have additive effects, as hypothesized, suggesting a ceiling effect of neuroinflammation may exist in response to multiple pollutants.

  6. Combined Effects of Exposure to Dim Light at Night and Fine Particulate Matter on C3H/HeNHsd Mice

    PubMed Central

    Hogan, Matthew K.; Kovalycsik, Taylor; Sun, Qinghua; Rajagopalan, Sanjay; Nelson, Randy J.

    2016-01-01

    Air and light pollution contribute to fetal abnormalities, increase prevalence of cancer, metabolic and cardiorespiratory diseases, and central nervous system (CNS) disorders. A component of air pollution, particulate matter, and the phenomenon of dim light at night (dLAN) both result in neuroinflammation, which has been implicated in several CNS disorders. The combinatorial role of these pollutants on health outcomes has not been assessed. Male C3H/HeNHsd mice, with intact melatonin production, were used to model humans exposed to circadian disruption by dLAN and contaminated environmental air. We hypothesized exposure to 2.5μm of particulate matter (PM2.5) and dLAN (5 lux) combines to upregulate neuroinflammatory cytokine expression and alter hippocampal morphology compared to mice exposed to filtered air (FA) and housed under dark nights (LD). We also hypothesized that exposure to PM2.5 and dLAN provokes anxiety-like and depressive-like responses. For four weeks, four groups of mice were simultaneously exposed to ambient concentrated PM2.5 or FA and/or dLAN or LD. Following exposure, mice underwent several behavioral assays and hippocampi were collected for qPCR and morphological analyses. Our results are generally comparable to previous PM2.5 and dLAN reports conducted on mice and implicate PM2.5 and dLAN as potential factors contributing to depression and anxiety. Short-term exposure to PM2.5 and dLAN upregulated neuroinflammatory cytokines and altered CA1 hippocampal structural changes, as well as provoked depressive-like responses (anhedonia). However, combined, PM2.5 and dLAN exposure did not have additive effects, as hypothesized, suggesting a ceiling effect of neuroinflammation may exist in response to multiple pollutants. PMID:26235330

  7. Circadian phase typing in idiopathic generalized epilepsy: Dim light melatonin onset and patterns of melatonin secretion-Semicurve findings in adult patients.

    PubMed

    Manni, Raffaele; De Icco, Roberto; Cremascoli, Riccardo; Ferrera, Giulia; Furia, Francesca; Zambrelli, Elena; Canevini, Maria Paola; Terzaghi, Michele

    2016-08-01

    It has been debated in the literature whether patients with idiopathic generalized epilepsy (IGE) have a distinctive, evening-oriented chronotype. The few questionnaire-based studies that are available in the literature have conflicting results. The aim of our study was to define chronotype in patients with IGE by determining dim light melatonin onset (DLMO). Twenty adults diagnosed with IGE (grand mal on awakening [GM] in 7 cases and juvenile myoclonic epilepsy in 13 cases) were investigated by means of a face-to-face semistructured sleep interview, Morningness-Eveningness Questionnaire (MEQ), Pittsburgh Sleep Quality Index (PSQI) questionnaire, and a melatonin salivary test with DLMO determination. Eighteen healthy subjects (HC) and 28 patients affected with cryptogenic focal epilepsy (FE) served as controls. The mean MEQ score was significantly lower in patients with IGE than that in patients with FE (49.1±5.9 versus 56.1±8.7 P<0.01) but not significantly lower than that in HC (49.1±5.9 versus 49.3±8.6). Midsleep on free days corrected for sleep duration did not differ significantly between the three subject groups (04:59±01:21h, 04:37±01:17h, 04:29±00:52h). The mean DLMO time in patients with IGE (22:13±01:34h) occurred 49min later than that in HC (21.24±1h), and the melatonin surge within the 30-minute time interval after DLMO in patients with IGE was significantly lower than that in HC (1.51±2.7 versus 3.8±3.6pg/mL P=0.045). Subjective measures of chronotype do not indicate a definite evening-oriented chronotype in patients with IGE. However, the data concerning endogenous melatonin secretion indicate that patients with IGE tend to have a late circadian phase. Further studies are warranted in order to better define the late pattern of endogenous melatonin secretion in patients with IGE and to ascertain the role of this pattern in influencing behavioral chronotype in these subjects. Copyright © 2016. Published by Elsevier Inc.

  8. Effects of forward and backward transitions in light intensities in tau-illuminance curves of the rat motor activity rhythm under constant dim light.

    PubMed

    Cambras, Trinitat; Díez-Noguera, Antoni

    2012-07-01

    exposure to 1 lux. Females became arrhythmic at 1 lux, and only one half of them recovered their circadian rhythm at .02 lux. The other one half remained arrhythmic even under dim red light. Thus, some of the results of this paper contradict the predictions of standard descriptions of the functioning of the circadian clock, possibly due to the effects of dim light.

  9. Mercury-induced dark-state instability and photobleaching alterations of the visual g-protein coupled receptor rhodopsin.

    PubMed

    Morillo, Margarita; Toledo, Darwin; Pérez, Juan Jesús; Ramon, Eva; Garriga, Pere

    2014-07-21

    Mercuric compounds were previously shown to affect the visual phototransduction cascade, and this could result in vision impairment. We have analyzed the effect of mercuric chloride on the structure and stability of the dim light vision photoreceptor rhodopsin. For this purpose, we have used both native rhodopsin immunopurified from bovine retinas and a recombinant mutant rhodopsin carrying several Cys to Ser substitutions in order to investigate the potential binding site of mercury on the receptor. Our results show that mercuric chloride dramatically reduces the stability of dark-state rhodopsin and alters the molecular features of the photoactived conformation obtained upon illumination by eliciting the formation of an altered photointermediate. The thermal bleaching kinetics of native and mutant rhodopsin is markedly accelerated by mercury in a concentration-dependent manner, and its chromophore regeneration ability is severely reduced without significantly affecting its G-protein activation capacity. Furthermore, fluorescence spectroscopic measurements on the retinal release process, ensuing illumination, suggest that mercury impairs complete retinal release from the receptor binding pocket. Our results provide further support for the capacity of mercury as a hazardous metal ion with reported deleterious effect on vision and provide a molecular explanation for such an effect at the rhodopsin photoreceptor level. We suggest that mercury could alter vision by acting in a specific manner on the molecular components of the retinoid cycle, particularly by modifying the ability of the visual photoreceptor protein rhodopsin to be regenerated and to be normally photoactivated by light.

  10. Structural approaches to understanding retinal proteins needed for vision

    PubMed Central

    Orban, Tivadar; Jastrzebska, Beata; Palczewski, Krzysztof

    2014-01-01

    The past decade has witnessed an impressive expansion of our knowledge of retinal photoreceptor signal transduction and the regulation of the visual cycle required for normal eyesight. Progress in human genetics and next generation sequencing technologies have revealed the complexity behind many inherited retinal diseases. Structural studies have markedly increased our understanding of the visual process. Moreover, technical innovations and improved methodologies in proteomics, macromolecular crystallization and high resolution imaging at different levels set the scene for even greater advances. Pharmacology combined with structural biology of membrane proteins holds great promise for developing innovative accessible therapies for millions robbed of their sight or progressing toward blindness. PMID:24680428

  11. Structural approaches to understanding retinal proteins needed for vision.

    PubMed

    Orban, Tivadar; Jastrzebska, Beata; Palczewski, Krzysztof

    2014-04-01

    The past decade has witnessed an impressive expansion of our knowledge of retinal photoreceptor signal transduction and the regulation of the visual cycle required for normal eyesight. Progress in human genetics and next generation sequencing technologies have revealed the complexity behind many inherited retinal diseases. Structural studies have markedly increased our understanding of the visual process. Moreover, technical innovations and improved methodologies in proteomics, macromolecular crystallization and high resolution imaging at different levels set the scene for even greater advances. Pharmacology combined with structural biology of membrane proteins holds great promise for developing innovative accessible therapies for millions robbed of their sight or progressing toward blindness. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. CoMOGrad and PHOG: From Computer Vision to Fast and Accurate Protein Tertiary Structure Retrieval

    PubMed Central

    Karim, Rezaul; Aziz, Mohd. Momin Al; Shatabda, Swakkhar; Rahman, M. Sohel; Mia, Md. Abul Kashem; Zaman, Farhana; Rakin, Salman

    2015-01-01

    The number of entries in a structural database of proteins is increasing day by day. Methods for retrieving protein tertiary structures from such a large database have turn out to be the key to comparative analysis of structures that plays an important role to understand proteins and their functions. In this paper, we present fast and accurate methods for the retrieval of proteins having tertiary structures similar to a query protein from a large database. Our proposed methods borrow ideas from the field of computer vision. The speed and accuracy of our methods come from the two newly introduced features- the co-occurrence matrix of the oriented gradient and pyramid histogram of oriented gradient- and the use of Euclidean distance as the distance measure. Experimental results clearly indicate the superiority of our approach in both running time and accuracy. Our method is readily available for use from this website: http://research.buet.ac.bd:8080/Comograd/. PMID:26293226

  13. Insect photoreceptor adaptations to night vision.

    PubMed

    Honkanen, Anna; Immonen, Esa-Ville; Salmela, Iikka; Heimonen, Kyösti; Weckström, Matti

    2017-04-05

    Night vision is ultimately about extracting information from a noisy visual input. Several species of nocturnal insects exhibit complex visually guided behaviour in conditions where most animals are practically blind. The compound eyes of nocturnal insects produce strong responses to single photons and process them into meaningful neural signals, which are amplified by specialized neuroanatomical structures. While a lot is known about the light responses and the anatomical structures that promote pooling of responses to increase sensitivity, there is still a dearth of knowledge on the physiology of night vision. Retinal photoreceptors form the first bottleneck for the transfer of visual information. In this review, we cover the basics of what is known about physiological adaptations of insect photoreceptors for low-light vision. We will also discuss major enigmas of some of the functional properties of nocturnal photoreceptors, and describe recent advances in methodologies that may help to solve them and broaden the field of insect vision research to new model animals.This article is part of the themed issue 'Vision in dim light'.

  14. Bird colour vision: behavioural thresholds reveal receptor noise.

    PubMed

    Olsson, Peter; Lind, Olle; Kelber, Almut

    2015-01-15

    Birds have impressive physiological adaptations for colour vision, including tetrachromacy and coloured oil droplets, yet it is not clear exactly how well birds can discriminate the reflecting object colours that they encounter in nature. With behavioural experiments, we determined colour discrimination thresholds of chickens in bright and dim light. We performed the experiments with two colour series, orange and green, covering two parts of chicken colour space. These experiments allowed us to compare behavioural results with model expectations and determine how different noise types limit colour discrimination. At intensities ranging from bright light to those corresponding to early dusk (250-10 cd m(-2)), we describe thresholds accurately by assuming a constant signal-to-noise ratio, in agreement with an invariant Weber fraction of Weber's law. Below this intensity, signal-to-noise ratio decreases and Weber's law is violated because photon-shot noise limits colour discrimination. In very dim light (below 0.05 cd m(-2) for the orange series or 0.2 cd m(-2) for the green series) colour discrimination is possibly constrained by dark noise, and the lowest intensity at which chickens can discriminate colours is 0.025 and 0.08 cd m(-2) for the orange and green series, respectively. Our results suggest that chickens use spatial pooling of cone outputs to mitigate photon-shot noise. Surprisingly, we found no difference between colour discrimination of chickens and humans tested with the same test in bright light.

  15. A neuronal circuit for colour vision based on rod-cone opponency.

    PubMed

    Joesch, Maximilian; Meister, Markus

    2016-04-14

    In bright light, cone-photoreceptors are active and colour vision derives from a comparison of signals in cones with different visual pigments. This comparison begins in the retina, where certain retinal ganglion cells have 'colour-opponent' visual responses-excited by light of one colour and suppressed by another colour. In dim light, rod-photoreceptors are active, but colour vision is impossible because they all use the same visual pigment. Instead, the rod signals are thought to splice into retinal circuits at various points, in synergy with the cone signals. Here we report a new circuit for colour vision that challenges these expectations. A genetically identified type of mouse retinal ganglion cell called JAMB (J-RGC), was found to have colour-opponent responses, OFF to ultraviolet (UV) light and ON to green light. Although the mouse retina contains a green-sensitive cone, the ON response instead originates in rods. Rods and cones both contribute to the response over several decades of light intensity. Remarkably, the rod signal in this circuit is antagonistic to that from cones. For rodents, this UV-green channel may play a role in social communication, as suggested by spectral measurements from the environment. In the human retina, all of the components for this circuit exist as well, and its function can explain certain experiences of colour in dim lights, such as a 'blue shift' in twilight. The discovery of this genetically defined pathway will enable new targeted studies of colour processing in the brain.

  16. Luminance-dependence of spatial vision in budgerigars (Melopsittacus undulatus) and Bourke's parrots (Neopsephotus bourkii).

    PubMed

    Lind, Olle; Sunesson, Tony; Mitkus, Mindaugas; Kelber, Almut

    2012-01-01

    Budgerigars (Melopsittacus undulatus) and Bourke's parrots (Neopsephotus bourkii) are closely related birds with different activity patterns. Budgerigars are strictly diurnal while Bourke's parrots are active in dim twilight. Earlier studies show that the intensity threshold of colour vision is similar in both species while Bourke's parrots have larger eyes with a higher density of rods than budgerigars. In this study, we investigate whether this could be an adaptation for better spatial vision in dim light. We used two alternative forced-choice experiments to determine the spatial acuity of both species at light intensities ranging from 0.08 to 73 cd/m(2). We also determined the spatial contrast sensitivity function (CSF) for bright light in Bourke's parrots and compare it to existing data for budgerigars. The spatial acuity of Bourke's parrots was found to be similar to that of budgerigars at all light levels. Also the CSF of Bourke's parrots is similar to that of budgerigars with a sensitivity peak located between 2.1 and 2.6 cycles/degree. Our findings do not support the hypothesis that Bourke's parrots have superior spatial acuity in dim light compared to budgerigars and the adaptive value of the relatively rod-rich and large eyes of Bourke's parrots remains unclear.

  17. Tracking G-protein-coupled receptor activation using genetically encoded infrared probes.

    PubMed

    Ye, Shixin; Zaitseva, Ekaterina; Caltabiano, Gianluigi; Schertler, Gebhard F X; Sakmar, Thomas P; Deupi, Xavier; Vogel, Reiner

    2010-04-29

    Rhodopsin is a prototypical heptahelical family A G-protein-coupled receptor (GPCR) responsible for dim-light vision. Light isomerizes rhodopsin's retinal chromophore and triggers concerted movements of transmembrane helices, including an outward tilting of helix 6 (H6) and a smaller movement of H5, to create a site for G-protein binding and activation. However, the precise temporal sequence and mechanism underlying these helix rearrangements is unclear. We used site-directed non-natural amino acid mutagenesis to engineer rhodopsin with p-azido-l-phenylalanine residues incorporated at selected sites, and monitored the azido vibrational signatures using infrared spectroscopy as rhodopsin proceeded along its activation pathway. Here we report significant changes in electrostatic environments of the azido probes even in the inactive photoproduct Meta I, well before the active receptor state was formed. These early changes suggest a significant rotation of H6 and movement of the cytoplasmic part of H5 away from H3. Subsequently, a large outward tilt of H6 leads to opening of the cytoplasmic surface to form the active receptor photoproduct Meta II. Thus, our results reveal early conformational changes that precede larger rigid-body helix movements, and provide a basis to interpret recent GPCR crystal structures and to understand conformational sub-states observed during the activation of other GPCRs.

  18. Computer vision-based automated peak picking applied to protein NMR spectra.

    PubMed

    Klukowski, Piotr; Walczak, Michal J; Gonczarek, Adam; Boudet, Julien; Wider, Gerhard

    2015-09-15

    A detailed analysis of multidimensional NMR spectra of macromolecules requires the identification of individual resonances (peaks). This task can be tedious and time-consuming and often requires support by experienced users. Automated peak picking algorithms were introduced more than 25 years ago, but there are still major deficiencies/flaws that often prevent complete and error free peak picking of biological macromolecule spectra. The major challenges of automated peak picking algorithms is both the distinction of artifacts from real peaks particularly from those with irregular shapes and also picking peaks in spectral regions with overlapping resonances which are very hard to resolve by existing computer algorithms. In both of these cases a visual inspection approach could be more effective than a 'blind' algorithm. We present a novel approach using computer vision (CV) methodology which could be better adapted to the problem of peak recognition. After suitable 'training' we successfully applied the CV algorithm to spectra of medium-sized soluble proteins up to molecular weights of 26 kDa and to a 130 kDa complex of a tetrameric membrane protein in detergent micelles. Our CV approach outperforms commonly used programs. With suitable training datasets the application of the presented method can be extended to automated peak picking in multidimensional spectra of nucleic acids or carbohydrates and adapted to solid-state NMR spectra. CV-Peak Picker is available upon request from the authors. gsw@mol.biol.ethz.ch; michal.walczak@mol.biol.ethz.ch; adam.gonczarek@pwr.edu.pl Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  19. The intensity threshold of colour vision in a passerine bird, the blue tit (Cyanistes caeruleus).

    PubMed

    Gomez, Doris; Grégoire, Arnaud; Del Rey Granado, Maria; Bassoul, Marine; Degueldre, David; Perret, Philippe; Doutrelant, Claire

    2014-11-01

    Many vertebrates use colour vision for vital behaviour but their visual performance in dim light is largely unknown. The light intensity threshold of colour vision is known only for humans, horses and two parrot species. Here, we first explore this threshold in a passerine bird, the blue tit (Cyanistes caeruleus). Using classic conditioning of colour cues to food rewards in three individuals, we find a threshold ranging from 0.05 to 0.2 cd m(-2). Results are comparable to the two previously tested bird species. For tits, nest light conditions probably exceed that threshold, at least after sunrise. These results shed new light on the lively debate questioning the visual performance of cavity nesters and the evolutionary significance of egg and chick coloration. Although this needs further investigation, it is possible that blue tits exploit both colour and brightness cues when viewing their eggs, chicks or conspecifics in their nests. © 2014. Published by The Company of Biologists Ltd.

  20. The remarkable visual capacities of nocturnal insects: vision at the limits with small eyes and tiny brains.

    PubMed

    Warrant, Eric J

    2017-04-05

    Nocturnal insects have evolved remarkable visual capacities, despite small eyes and tiny brains. They can see colour, control flight and land, react to faint movements in their environment, navigate using dim celestial cues and find their way home after a long and tortuous foraging trip using learned visual landmarks. These impressive visual abilities occur at light levels when only a trickle of photons are being absorbed by each photoreceptor, begging the question of how the visual system nonetheless generates the reliable signals needed to steer behaviour. In this review, I attempt to provide an answer to this question. Part of the answer lies in their compound eyes, which maximize light capture. Part lies in the slow responses and high gains of their photoreceptors, which improve the reliability of visual signals. And a very large part lies in the spatial and temporal summation of these signals in the optic lobe, a strategy that substantially enhances contrast sensitivity in dim light and allows nocturnal insects to see a brighter world, albeit a slower and coarser one. What is abundantly clear, however, is that during their evolution insects have overcome several serious potential visual limitations, endowing them with truly extraordinary night vision.This article is part of the themed issue 'Vision in dim light'.

  1. Changes to colour vision on exposure to high altitude.

    PubMed

    Davies, A J; Morris, D S; Kalson, N S; Wright, A D; Imray, C H E; Hogg, C R

    2011-03-01

    Several studies have shown deterioration in colour vision at altitudes above 3,000m. These studies have been conducted in photopic (bright daylight) conditions, whereas many military operations take place in mesopic (dim light) conditions. Data suggests that the tritan colour vision axis (blue cones, TA) are more susceptible to hypoxic insult than protan axis (red cones, PA). The objective of this study was to examine colour vision at high altitude, in mesopic conditions, and using a novel method of assessment to discriminate between the tritan and protan axis. We examined 42 eyes (21 subjects, mean age 44, range 22-71), at sea level and within 12-36 hours of exposure to 3300m. This was done in a darkened room, with refractive error correction. Colour vision was studied using ChromaTest, a software programme that analyzes colour contrast threshold (CCT) of both TA and PA. We planned to repeat CCT measurement at 4,392m, but technology failure prevented this. Non-parametric paired data was examined using the Wilcoxon signed rank test. There was found to be no change to either the PA (p = 0.409) or the TA (p = 0.871) upon ascent. Within the PA 16 eyes had a lower CCT at high altitude, whilst 26 were higher. In the TA 20 eyes had a lower CCT and 22 were higher. At sea level, mean CCT for PA was 4.21 (SD 2.29) TA was 7.06 (SD 1.77). At 3,300m mean CCT for PA was 4.36 (SD 2.86) and TA was 6.93 (SD 2.39). This experiment revealed no changes to colour vision with exposure to 3,300m. This may be below the threshold altitude for cone dysfunction, alternatively colour vision deterioration may be less significant in mesopic conditions.

  2. Reproducibility of an objective four-choice canine vision testing technique that assesses vision at differing light intensities.

    PubMed

    Annear, Matthew J; Gornik, Kara R; Venturi, Francesca L; Hauptman, Joe G; Bartoe, Joshua T; Petersen-Jones, Simon M

    2013-09-01

    The increasing importance of canine retinal dystrophy models means accurate vision testing is needed. This study was performed to evaluate a four-choice vision testing technique for any difference in outcome measures with repeated evaluations of the same dogs.   Four 11-month-old RPE65-deficient dogs. Vision was evaluated using a previously described four-choice vision testing device. Four evaluations were performed at 2-week intervals. Vision was assessed at six different white light intensities (bright through dim), and each eye was evaluated separately. The ability to select the one of the four exit tunnels that was open at the far end was assessed ('choice of exit') and recorded as correct or incorrect first tunnel choice. 'Time to exit' the device was also recorded. Both outcomes were analyzed for significance using anova. We hypothesized that performance would improve with repeated testing (more correct choices and more rapid time to exit). 'Choice of exit' did not vary significantly between each evaluation (P = 0.12), in contrast 'time to exit' increased significantly (P = 0.012), and showed greater variability in dim light conditions. We found no evidence to support the hypothesis that either measure of outcome worsened with repeated testing; in fact, the 'time to exit' outcome worsened rather than improved. The 'choice of exit' gave consistent results between trials. These outcome data indicate the importance of including a choice-based assessment of vision in addition to measurement of device transit time. © 2012 American College of Veterinary Ophthalmologists.

  3. Intermolecular Interaction between Anchoring Subunits Specify Subcellular Targeting and Function of RGS Proteins in Retina ON-Bipolar Neurons.

    PubMed

    Sarria, Ignacio; Orlandi, Cesare; McCall, Maureen A; Gregg, Ronald G; Martemyanov, Kirill A

    2016-03-09

    In vertebrate retina, light responses generated by the rod photoreceptors are transmitted to the second-order neurons, the ON-bipolar cells (ON-BC), and this communication is indispensible for vision in dim light. In ON-BCs, synaptic transmission is initiated by the metabotropic glutamate receptor, mGluR6, that signals via the G-protein Go to control opening of the effector ion channel, TRPM1. A key role in this process belongs to the GTPase Activating Protein (GAP) complex that catalyzes Go inactivation upon light-induced suppression of glutamate release in rod photoreceptors, thereby driving ON-BC depolarization to changes in synaptic input. The GAP complex has a striking molecular complexity. It contains two Regulator of G-protein Signaling (RGS) proteins RGS7 and RGS11 that directly act on Go and two adaptor subunits: RGS Anchor Protein (R9AP) and the orphan receptor, GPR179. Here we examined the organizational principles of the GAP complex in ON-BCs. Biochemical experiments revealed that RGS7 binds to a conserved site in GPR179 and that RGS11 in vivo forms a complex only with R9AP. R9AP and GPR179 are further integrated via direct protein-protein interactions involving their cytoplasmic domains. Elimination of GPR179 prevents postsynaptic accumulation of R9AP. Furthermore, concurrent knock-out of both R9AP and RGS7 does not reconfigure the GAP complex and completely abolishes synaptic transmission, resulting in a novel mouse model of night blindness. Based on these results, we propose a model of hierarchical assembly and function of the GAP complex that supports ON-BCs visual signaling.

  4. Behavioural and physiological limits to vision in mammals.

    PubMed

    Field, Greg D; Sampath, Alapakkam P

    2017-04-05

    Human vision is exquisitely sensitive-a dark-adapted observer is capable of reliably detecting the absorption of a few quanta of light. Such sensitivity requires that the sensory receptors of the retina, rod photoreceptors, generate a reliable signal when single photons are absorbed. In addition, the retina must be able to extract this information and relay it to higher visual centres under conditions where very few rods signal single-photon responses while the majority generate only noise. Critical to signal transmission are mechanistic optimizations within rods and their dedicated retinal circuits that enhance the discriminability of single-photon responses by mitigating photoreceptor and synaptic noise. We describe behavioural experiments over the past century that have led to the appreciation of high sensitivity near absolute visual threshold. We further consider mechanisms within rod photoreceptors and dedicated rod circuits that act to extract single-photon responses from cellular noise. We highlight how these studies have shaped our understanding of brain function and point out several unresolved questions in the processing of light near the visual threshold.This article is part of the themed issue 'Vision in dim light'.

  5. Self-organized criticality and color vision: A guide to water-protein landscape evolution

    NASA Astrophysics Data System (ADS)

    Phillips, J. C.

    2013-02-01

    We focus here on the scaling properties of small interspecies differences between red cone opsin transmembrane proteins, using a hydropathic elastic roughening tool previously applied to the rhodopsin rod transmembrane proteins. This tool is based on a non-Euclidean hydropathic metric realistically rooted in the atomic coordinates of 5526 protein segments, which thereby encapsulates universal non-Euclidean long-range differential geometrical features of water films enveloping globular proteins in the Protein Data Bank. Whereas the rhodopsin blue rod water films are smoothest in humans, the red cone opsins’ water films are optimized for smoothness in cats and elephants, consistent with protein species landscapes that evolve differently in different contexts. We also analyze red cone opsins in the chromatophore-containing family of chameleons, snakes, zebrafish and goldfish, where short- and long-range (BLAST and hydropathic) amino acid (aa) correlations are found with values as large as 97%-99%. We use hydropathic aa optimization to estimate the maximum number Nmax of color shades that the human eye can discriminate, and obtain 106

  6. The N-terminal region of centrosomal protein 290 (CEP290) restores vision in a zebrafish model of human blindness.

    PubMed

    Baye, Lisa M; Patrinostro, Xiaobai; Swaminathan, Svetha; Beck, John S; Zhang, Yan; Stone, Edwin M; Sheffield, Val C; Slusarski, Diane C

    2011-04-15

    The gene coding for centrosomal protein 290 (CEP290), a large multidomain protein, is the most frequently mutated gene underlying the non-syndromic blinding disorder Leber's congenital amaurosis (LCA). CEP290 has also been implicated in several cilia-related syndromic disorders including Meckel-Gruber syndrome, Joubert syndrome, Senor-Loken syndrome and Bardet-Biedl syndrome (BBS). In this study, we characterize the developmental and functional roles of cep290 in zebrafish. An antisense oligonucleotide [Morpholino (MO)], designed to generate an altered cep290 splice product that models the most common LCA mutation, was used for gene knockdown. We show that cep290 MO-injected embryos have reduced Kupffer's vesicle size and delays in melanosome transport, two phenotypes that are observed upon knockdown of bbs genes in zebrafish. Consistent with a role in cilia function, the cep290 MO-injected embryos exhibited a curved body axis. Patients with LCA caused by mutations in CEP290 have reduced visual perception, although they present with a fully laminated retina. Similarly, the histological examination of retinas from cep290 MO-injected zebrafish revealed no gross lamination defects, yet the embryos had a statistically significant reduction in visual function. Finally, we demonstrate that the vision impairment caused by the disruption of cep290 can be rescued by expressing only the N-terminal region of the human CEP290 protein. These data reveal that a specific region of the CEP290 protein is sufficient to restore visual function and this region may be a viable gene therapy target for LCA patients with mutations in CEP290.

  7. The N-terminal region of centrosomal protein 290 (CEP290) restores vision in a zebrafish model of human blindness

    PubMed Central

    Baye, Lisa M.; Patrinostro, Xiaobai; Swaminathan, Svetha; Beck, John S.; Zhang, Yan; Stone, Edwin M.; Sheffield, Val C.; Slusarski, Diane C.

    2011-01-01

    The gene coding for centrosomal protein 290 (CEP290), a large multidomain protein, is the most frequently mutated gene underlying the non-syndromic blinding disorder Leber's congenital amaurosis (LCA). CEP290 has also been implicated in several cilia-related syndromic disorders including Meckel–Gruber syndrome, Joubert syndrome, Senor–Loken syndrome and Bardet–Biedl syndrome (BBS). In this study, we characterize the developmental and functional roles of cep290 in zebrafish. An antisense oligonucleotide [Morpholino (MO)], designed to generate an altered cep290 splice product that models the most common LCA mutation, was used for gene knockdown. We show that cep290 MO-injected embryos have reduced Kupffer's vesicle size and delays in melanosome transport, two phenotypes that are observed upon knockdown of bbs genes in zebrafish. Consistent with a role in cilia function, the cep290 MO-injected embryos exhibited a curved body axis. Patients with LCA caused by mutations in CEP290 have reduced visual perception, although they present with a fully laminated retina. Similarly, the histological examination of retinas from cep290 MO-injected zebrafish revealed no gross lamination defects, yet the embryos had a statistically significant reduction in visual function. Finally, we demonstrate that the vision impairment caused by the disruption of cep290 can be rescued by expressing only the N-terminal region of the human CEP290 protein. These data reveal that a specific region of the CEP290 protein is sufficient to restore visual function and this region may be a viable gene therapy target for LCA patients with mutations in CEP290. PMID:21257638

  8. The ChromaGen contact lens system: colour vision test results and subjective responses.

    PubMed

    Swarbrick, H A; Nguyen, P; Nguyen, T; Pham, P

    2001-05-01

    The ChromaGen lens system is designed to enhance colour perception in colour vision deficiency (CVD). To investigate its efficacy, 14 CVD subjects were prescribed ChromaGen contact lenses. Colour vision tests (Ishihara, Farnsworth Munsell D-15, Farnsworth Lantern) were administered at baseline, lens dispensing, and after a 2-week lens-wearing trial during which subjective responses were recorded daily using visual analogue scales. ChromaGen lenses significantly reduced ishihara error rates (p < 0.001; ANOVA), particularly for deutan subjects. There was also a significant reduction in errors (p < 0.005) on the D-15 test. Conversely, lens wear had no significant effect on Farnsworth Lantern test performance. Subjectively, subjects reported enhanced colour perception, but poor vision in dim light. Judgement of distance and motion were only slightly affected. We conclude that ChromaGen lenses may enhance subjective colour experience and assist in certain colour-related tasks, but are not indicated as an aid for CVD in occupations with colour vision-related restrictions.

  9. Vision problems

    MedlinePlus

    ... which nothing can be seen) Vision loss and blindness are the most severe vision problems. Considerations Regular ... that look faded. The most common cause of blindness in people over age 60. Eye infection, inflammation, ...

  10. Field Commissioning of a Daylight-Dimming Lighting System.

    ERIC Educational Resources Information Center

    Floyd, David B.; Parker, Danny S.

    A Florida elementary school cafeteria, retrofitted with a fluorescent lighting system that dims in response to available daylight, was evaluated through real time measurement of lighting and air conditioning power, work plane illumination, and interior/exterior site conditions. The new system produced a 27 percent reduction in lighting power due…

  11. All Vision Impairment

    MedlinePlus

    ... USAJobs Home > Statistics and Data > All Vision Impairment All Vision Impairment Vision Impairment Defined Vision impairment is ... being blind by the U.S. definition.) The category “All Vision Impairment” includes both low vision and blindness. ...

  12. Computer vision

    NASA Technical Reports Server (NTRS)

    Gennery, D.; Cunningham, R.; Saund, E.; High, J.; Ruoff, C.

    1981-01-01

    The field of computer vision is surveyed and assessed, key research issues are identified, and possibilities for a future vision system are discussed. The problems of descriptions of two and three dimensional worlds are discussed. The representation of such features as texture, edges, curves, and corners are detailed. Recognition methods are described in which cross correlation coefficients are maximized or numerical values for a set of features are measured. Object tracking is discussed in terms of the robust matching algorithms that must be devised. Stereo vision, camera control and calibration, and the hardware and systems architecture are discussed.

  13. Computational vision

    NASA Technical Reports Server (NTRS)

    Barrow, H. G.; Tenenbaum, J. M.

    1981-01-01

    The range of fundamental computational principles underlying human vision that equally apply to artificial and natural systems is surveyed. There emerges from research a view of the structuring of vision systems as a sequence of levels of representation, with the initial levels being primarily iconic (edges, regions, gradients) and the highest symbolic (surfaces, objects, scenes). Intermediate levels are constrained by information made available by preceding levels and information required by subsequent levels. In particular, it appears that physical and three-dimensional surface characteristics provide a critical transition from iconic to symbolic representations. A plausible vision system design incorporating these principles is outlined, and its key computational processes are elaborated.

  14. Improving Vision

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Many people are familiar with the popular science fiction series Star Trek: The Next Generation, a show featuring a blind character named Geordi La Forge, whose visor-like glasses enable him to see. What many people do not know is that a product very similar to Geordi's glasses is available to assist people with vision conditions, and a NASA engineer's expertise contributed to its development. The JORDY(trademark) (Joint Optical Reflective Display) device, designed and manufactured by a privately-held medical device company known as Enhanced Vision, enables people with low vision to read, write, and watch television. Low vision, which includes macular degeneration, diabetic retinopathy, and glaucoma, describes eyesight that is 20/70 or worse, and cannot be fully corrected with conventional glasses.

  15. Vision Underwater.

    ERIC Educational Resources Information Center

    Levine, Joseph S.

    1980-01-01

    Provides information regarding underwater vision. Includes a discussion of optically important interfaces, increased eye size of organisms at greater depths, visual peculiarities regarding the habitat of the coastal environment, and various pigment visual systems. (CS)

  16. Vision Underwater.

    ERIC Educational Resources Information Center

    Levine, Joseph S.

    1980-01-01

    Provides information regarding underwater vision. Includes a discussion of optically important interfaces, increased eye size of organisms at greater depths, visual peculiarities regarding the habitat of the coastal environment, and various pigment visual systems. (CS)

  17. [Central vision].

    PubMed

    Fahle, M

    2004-07-01

    The clinical assessment of vision by means of optotypes does by no means test just two-point resolution, since a correct naming of the letters or digits requires a preceding visual object recognition. Cortical lesions can massively deteriorate vision up to a "Seelenblindheit" in spite of intact optics and retina. There are different processing levels involved in the analysis which can be individually defective, leading to disorders from visual indiscrimination to agnosia or anomia.

  18. Color vision.

    PubMed

    Swanson, William H; Cohen, Jay M

    2003-06-01

    Many visual disorders produce acquired color vision defects. Color vision theory emphasizes several stages of visual processing: prereceptoral filters (lens, macular pigment, pupil), cone photopigments (L-, M-, and S-cones), and postreceptoral processes (red-green, S-cone, and luminance channels). Congenital color defects, which affect 8% to 10% of males and 0.4% to 0.5% of females, result from alterations in the photopigment absorption spectra or the absence of one or more photopigments. The most common defects are color vision deficiencies (protan and deutan defects), which are milder than the rarer achromatopsias (complete loss of color vision). Acquired color vision defects can be attributed to a number of different causes: alteration of prereceptoral filters, reduced cone photopigment optical density, greater loss of one cone type than the others, and disruption of postreceptoral processes. Acquired color vision defects have been divided into three classes: type 1, red-green defect with scotopization; type 2, red-green defect without scotopization; and type 3, blue defects (with or without pseudoprotanomaly). Blue defects are usually type 3 acquired defects because congenital tritan defects have an incidence of one in several tens of thousands. Red-green defects can be acquired or congenital, and ruling out acquired defects can require a battery of tests (plates and arrangement tests, anomaloscopy, perhaps genetic analysis). Color vision tests must be administered carefully (with a standard illuminant and protocol), and pupillary miosis or high lens density should be noted and their possible effects considered when interpreting test results. Plate tests provide a simple screening method but do not provide a diagnosis. Arrangement tests and anomaloscope testing take more time and make greater demands on the tester, but they provide a more thorough evaluation. When standard protocols are followed and results are interpreted in terms of prereceptoral filters

  19. Training Visions

    ERIC Educational Resources Information Center

    Training, 2011

    2011-01-01

    In this article, "Training" asks the 2011 winners to give their predictions for what training--either in general or specifically at their companies--will look like in the next five to 10 years. Perhaps their "training visions" will spark some ideas in one's organization--or at least help prepare for what might be coming in the next decade or so.

  20. Presidential Visions.

    ERIC Educational Resources Information Center

    Gallin, Alice, Ed.

    1992-01-01

    This journal issue is devoted to the theme of university presidents and their visions of the future. It presents the inaugural addresses and speeches of 16 Catholic college and university presidents focusing on their goals, ambitions, and reasons for choosing to become higher education leaders at this particular time in the history of education in…

  1. Visions 2001.

    ERIC Educational Resources Information Center

    Rivero, Victor; Norman, Michele

    2001-01-01

    Reports on the views of 18 educational leaders regarding their vision on the future of education in an information age. Topics include people's diverse needs; relationships between morality, ethics, values, and technology; leadership; parental involvement; online courses from multiple higher education institutions; teachers' role; technology…

  2. Living with vision loss

    MedlinePlus

    Diabetes - vision loss; Retinopathy - vision loss; Low vision; Blindness - vision loss ... Peripheral (side) No light perception (NLP), or complete blindness A normally-sighted family member or friend may ...

  3. Blindness and vision loss

    MedlinePlus

    ... eye ( chemical burns or sports injuries) Diabetes Glaucoma Macular degeneration The type of partial vision loss may differ, ... tunnel vision and missing areas of vision With macular degeneration, the side vision is normal but the central ...

  4. Applied machine vision

    SciTech Connect

    Not Available

    1984-01-01

    This book presents the papers given at a conference on robot vision. Topics considered at the conference included the link between fixed and flexible automation, general applications of machine vision, the development of a specification for a machine vision system, machine vision technology, machine vision non-contact gaging, and vision in electronics manufacturing.

  5. Present Vision--Future Vision.

    ERIC Educational Resources Information Center

    Fitterman, L. Jeffrey

    This paper addresses issues of current and future technology use for and by individuals with visual impairments and blindness in Florida. Present technology applications used in vision programs in Florida are individually described, including video enlarging, speech output, large inkprint, braille print, paperless braille, and tactual output…

  6. Pleiades Visions

    NASA Astrophysics Data System (ADS)

    Whitehouse, M.

    2016-01-01

    Pleiades Visions (2012) is my new musical composition for organ that takes inspiration from traditional lore and music associated with the Pleiades (Seven Sisters) star cluster from Australian Aboriginal, Native American, and Native Hawaiian cultures. It is based on my doctoral dissertation research incorporating techniques from the fields of ethnomusicology and cultural astronomy; this research likely represents a new area of inquiry for both fields. This large-scale work employs the organ's vast sonic resources to evoke the majesty of the night sky and the expansive landscapes of the homelands of the above-mentioned peoples. Other important themes in Pleiades Visions are those of place, origins, cosmology, and the creation of the world.

  7. Computer vision

    SciTech Connect

    Not Available

    1982-01-01

    This paper discusses material from areas such as artificial intelligence, psychology, computer graphics, and image processing. The intent is to assemble a selection of this material in a form that will serve both as a senior/graduate-level academic text and as a useful reference to those building vision systems. This book has a strong artificial intelligence flavour, emphasising the belief that both the intrinsic image information and the internal model of the world are important in successful vision systems. The book is organised into four parts, based on descriptions of objects at four different levels of abstraction. These are: generalised images-images and image-like entities; segmented images-images organised into subimages that are likely to correspond to interesting objects; geometric structures-quantitative models of image and world structures; relational structures-complex symbolic descriptions of image and world structures. The book contains author and subject indexes.

  8. Cartesian visions.

    PubMed

    Fara, Patricia

    2008-12-01

    Few original portraits exist of René Descartes, yet his theories of vision were central to Enlightenment thought. French philosophers combined his emphasis on sight with the English approach of insisting that ideas are not innate, but must be built up from experience. In particular, Denis Diderot criticised Descartes's views by describing how Nicholas Saunderson--a blind physics professor at Cambridge--relied on touch. Diderot also made Saunderson the mouthpiece for some heretical arguments against the existence of God.

  9. Lambda Vision

    NASA Astrophysics Data System (ADS)

    Czajkowski, Michael

    2014-06-01

    There is an explosion in the quantity and quality of IMINT data being captured in Intelligence Surveillance and Reconnaissance (ISR) today. While automated exploitation techniques involving computer vision are arriving, only a few architectures can manage both the storage and bandwidth of large volumes of IMINT data and also present results to analysts quickly. Lockheed Martin Advanced Technology Laboratories (ATL) has been actively researching in the area of applying Big Data cloud computing techniques to computer vision applications. This paper presents the results of this work in adopting a Lambda Architecture to process and disseminate IMINT data using computer vision algorithms. The approach embodies an end-to-end solution by processing IMINT data from sensors to serving information products quickly to analysts, independent of the size of the data. The solution lies in dividing up the architecture into a speed layer for low-latent processing and a batch layer for higher quality answers at the expense of time, but in a robust and fault-tolerant way. This approach was evaluated using a large corpus of IMINT data collected by a C-130 Shadow Harvest sensor over Afghanistan from 2010 through 2012. The evaluation data corpus included full motion video from both narrow and wide area field-of-views. The evaluation was done on a scaled-out cloud infrastructure that is similar in composition to those found in the Intelligence Community. The paper shows experimental results to prove the scalability of the architecture and precision of its results using a computer vision algorithm designed to identify man-made objects in sparse data terrain.

  10. Artificial vision.

    PubMed

    Zarbin, M; Montemagno, C; Leary, J; Ritch, R

    2011-09-01

    A number treatment options are emerging for patients with retinal degenerative disease, including gene therapy, trophic factor therapy, visual cycle inhibitors (e.g., for patients with Stargardt disease and allied conditions), and cell transplantation. A radically different approach, which will augment but not replace these options, is termed neural prosthetics ("artificial vision"). Although rewiring of inner retinal circuits and inner retinal neuronal degeneration occur in association with photoreceptor degeneration in retinitis pigmentosa (RP), it is possible to create visually useful percepts by stimulating retinal ganglion cells electrically. This fact has lead to the development of techniques to induce photosensitivity in cells that are not light sensitive normally as well as to the development of the bionic retina. Advances in artificial vision continue at a robust pace. These advances are based on the use of molecular engineering and nanotechnology to render cells light-sensitive, to target ion channels to the appropriate cell type (e.g., bipolar cell) and/or cell region (e.g., dendritic tree vs. soma), and on sophisticated image processing algorithms that take advantage of our knowledge of signal processing in the retina. Combined with advances in gene therapy, pathway-based therapy, and cell-based therapy, "artificial vision" technologies create a powerful armamentarium with which ophthalmologists will be able to treat blindness in patients who have a variety of degenerative retinal diseases.

  11. Machine vision

    SciTech Connect

    Horn, D.

    1989-06-01

    To keep up with the speeds of modern production lines, most machine vision applications require very powerful computers (often parallel-processing machines), which process millions of points of data in real time. The human brain performs approximately 100 billion logical floating-point operations each second. That is 400 times the speed of a Cray-1 supercomputer. The right software must be developed for parallel-processing computers. The NSF has awarded Rensselaer Polytechnic Institute (Troy, N.Y.) a $2 million grant for parallel- and image-processing software research. Over the last 15 years, Rensselaer has been conducting image-processing research, including work with high-definition TV (HDTV) and image coding and understanding. A similar NSF grant has been awarded to Michigan State University (East Lansing, Mich.) Neural networks are supposed to emulate human learning patterns. These networks and their hardware implementations (neurocomputers) show a great deal of promise for machine vision systems because they allow the systems to understand the use sensory data input more effectively. Neurocomputers excel at pattern-recognition tasks when input data are fuzzy or the vision algorithm is not optimal and is difficult to ascertain.

  12. Bicistronic Lentiviruses Containing a Viral 2A Cleavage Sequence Reliably Co-Express Two Proteins and Restore Vision to an Animal Model of LCA1

    PubMed Central

    Verrier, Jonathan D.; Madorsky, Irina; Coggin, William E.; Geesey, Mero; Hochman, Michael; Walling, Elleanor; Daroszewski, Daniel; Eccles, Kristofer S.; Ludlow, Rachel; Semple-Rowland, Susan L.

    2011-01-01

    The disease processes underlying inherited retinal disease are complex and are not completely understood. Many of the corrective gene therapies designed to treat diseases linked to mutations in genes specifically expressed in photoreceptor cells restore function to these cells but fail to stop progression of the disease. There is growing consensus that effective treatments for these diseases will require delivery of multiple therapeutic proteins that will be selected to treat specific aspects of the disease process. The purpose of this study was to design a lentiviral transgene that reliably expresses all of the proteins it encodes and does so in a consistent manner among infected cells. We show, using both in vitro and in vivo analyses, that bicistronic lentiviral transgenes encoding two fluorescent proteins fused to a viral 2A-like cleavage peptide meet these expression criteria. To determine if this transgene design is suitable for therapeutic applications, we replaced one of the fluorescent protein genes with the gene encoding guanylate cyclase -1 (GC1) and delivered lentivirus carrying this transgene to the retinas of the GUCY1*B avian model of Leber congenital amaurosis – 1 (LCA1). GUCY1*B chickens carry a null mutation in the GC1 gene that disrupts photoreceptor function and causes blindness at hatching, a phenotype that closely matches that observed in humans with LCA1. We found that treatment of these animals with the 2A lentivector encoding GC1 restored vision to these animals as evidenced by the presence of optokinetic reflexes. We conclude that 2A-like peptides, with proper optimization, can be successfully incorporated into therapeutic vectors designed to deliver multiple proteins to neural retinal. These results highlight the potential of this vector design to serve as a platform for the development of combination therapies designed to enhance or prolong the benefits of corrective gene therapies. PMID:21647387

  13. Vision Therapy News Backgrounder.

    ERIC Educational Resources Information Center

    American Optometric Association, St. Louis, MO.

    The booklet provides an overview on vision therapy to aid writers, editors, and broadcasters help parents, teachers, older adults, and all consumers learn more about vision therapy. Following a description of vision therapy or vision training, information is provided on how and why vision therapy works. Additional sections address providers of…

  14. Vision Therapy News Backgrounder.

    ERIC Educational Resources Information Center

    American Optometric Association, St. Louis, MO.

    The booklet provides an overview on vision therapy to aid writers, editors, and broadcasters help parents, teachers, older adults, and all consumers learn more about vision therapy. Following a description of vision therapy or vision training, information is provided on how and why vision therapy works. Additional sections address providers of…

  15. Mutation of a conserved cysteine in the X-linked cone opsins causes color vision deficiencies by disrupting protein folding and stability.

    PubMed

    Kazmi, M A; Sakmar, T P; Ostrer, H

    1997-05-01

    To test the effects of disruption of a conserved cysteine in the green cone opsin molecule on light-activated isomerization, transducin activation, folding, transport, and protein half-life. Stable cell lines were established by transfecting 293-EBNA cells with a plasmid containing wild-type or mutant (C203R, C203S, C126S, C126S/C203S) green opsin cDNA molecules. The proteins were induced by culturing the cells in the presence of cadmium chloride and analyzed by spectra, transducin activation, Western blotting, pulse-labeling with immunoprecipitation, and immunocytochemistry. The C203R mutation disrupts the folding and half-life of the green opsin molecule and its abilities to absorb light at the appropriate wavelength and to activate transducin. Similar disruption of folding, half-life, and light activation occurs when Cys203 or its presumed partner for formation of a disulfide bond (Cys126) is replaced by serine residues. Like rhodopsin, the folding of the cone opsins appears to be dependent on the formation of a disulfide bond between the third transmembrane helix and the second extracellular loop. Disruption of this disulfide bond represents a cause of color vision deficiencies that is unrelated to spectral shifts of the photopigment.

  16. The Cytoplasmic Rhodopsin-Protein Interface: Potential for Drug Discovery

    PubMed Central

    Yanamala, Naveena; Gardner, Eric; Riciutti, Alec; Klein-Seetharaman, Judith

    2011-01-01

    The mammalian dim-light photoreceptor rhodopsin is a prototypic G protein coupled receptor (GPCR), interacting with the G protein, transducin, rhodopsin kinase, and arrestin. All of these proteins interact with rhodopsin at its cytoplasmic surface. Structural and modeling studies have provided in-depth descriptions of the respective interfaces. Overlap and thus competition for binding surfaces is a major regulatory mechanism for signal processing. Recently, it was found that the same surface is also targeted by small molecules. These ligands can directly interfere with the binding and activation of the proteins of the signal transduction cascade, but they can also allosterically modulate the retinal ligand binding pocket. Because the pocket that is targeted contains residues that are highly conserved across Class A GPCRs, these findings imply that it may be possible to target multiple GPCRs with the same ligand(s). This is desirable for example in complex diseases such as cancer where multiple GPCRs participate in the disease networks. PMID:21777183

  17. Color vision test

    MedlinePlus

    ... present from birth) color vision problems: Achromatopsia -- complete color blindness , seeing only shades of gray Deuteranopia -- difficulty telling ... Vision test - color; Ishihara color vision test Images Color blindness tests References Bowling B. Hereditary fundus dystrophies. In: ...

  18. Healthy Living, Healthy Vision

    MedlinePlus

    ... Eye Emergencies How to Jump Start a Car Battery Safely Electronic Screens and Your Eyes Nutrition and ... External Resources The Cost of Vision Problems The Future of Vision Vision Problems in the U.S. Healthy ...

  19. Pregnancy and Your Vision

    MedlinePlus

    ... Eye Emergencies How to Jump Start a Car Battery Safely Electronic Screens and Your Eyes Nutrition and ... External Resources The Cost of Vision Problems The Future of Vision Vision Problems in the U.S. Healthy ...

  20. Robot Vision

    NASA Technical Reports Server (NTRS)

    Sutro, L. L.; Lerman, J. B.

    1973-01-01

    The operation of a system is described that is built both to model the vision of primate animals, including man, and serve as a pre-prototype of possible object recognition system. It was employed in a series of experiments to determine the practicability of matching left and right images of a scene to determine the range and form of objects. The experiments started with computer generated random-dot stereograms as inputs and progressed through random square stereograms to a real scene. The major problems were the elimination of spurious matches, between the left and right views, and the interpretation of ambiguous regions, on the left side of an object that can be viewed only by the left camera, and on the right side of an object that can be viewed only by the right camera.

  1. Vision Screening

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The Visi Screen OSS-C, marketed by Vision Research Corporation, incorporates image processing technology originally developed by Marshall Space Flight Center. Its advantage in eye screening is speed. Because it requires no response from a subject, it can be used to detect eye problems in very young children. An electronic flash from a 35 millimeter camera sends light into a child's eyes, which is reflected back to the camera lens. The photorefractor then analyzes the retinal reflexes generated and produces an image of the child's eyes, which enables a trained observer to identify any defects. The device is used by pediatricians, day care centers and civic organizations that concentrate on children with special needs.

  2. Artificial vision.

    PubMed

    Humayun, M S; de Juan, E

    1998-01-01

    Outer retinal degenerations such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD) lead to blindness because of photoreceptor degeneration. To test whether controlled electrical stimulation of the remaining retinal neurons could provide form vision, we electrically stimulated the inner retinal surface with micro-electrodes inserted through the sclera/eye wall of 14 of these patients (12 RP and 2 AMD). This procedure was performed in the operating room under local anaesthesia and all responses were recorded via a video camera mounted on the surgical microscope. Electrical stimulation of the inner retinal surface elicited visual perception of a spot of light (phosphene) in all subjects. This perception was retinotopically correct in 13 of 14 patients. In a resolution test in a subject with no light perception, the patient could resolve phosphenes at 1.75 degrees centre-to-centre distance (i.e. visual acuity compatible with mobility; Snellen visual acuity of 4/200).

  3. Multicomputer vision

    SciTech Connect

    Levialdi, S. . Ist. di Genetica)

    1988-01-01

    The animating principle of these Workshops is to provide an informal frame of reference: more than reporting on current work participants speak out their doubts and problems in the design and development of algorithms, architectures or languages aimed at the best exploitation of multiprocessor systems. The typical problems that have been considered are: evaluation of systems and algorithms by means of cleverly thought benchmarks, representation of pictorial data and definition of the different levels of abstraction (from the pixel level to the symbolic one), definitions of the borderlines between low level and high level vision tasks, primitive functions that should necessarily be embedded in the elementary processing unit, ways to disseminate, reuse and expand existing software for image analysis.

  4. Binocular Vision

    PubMed Central

    Blake, Randolph; Wilson, Hugh

    2010-01-01

    This essay reviews major developments –empirical and theoretical –in the field of binocular vision during the last 25 years. We limit our survey primarily to work on human stereopsis, binocular rivalry and binocular contrast summation, with discussion where relevant of single-unit neurophysiology and human brain imaging. We identify several key controversies that have stimulated important work on these problems. In the case of stereopsis those controversies include position versus phase encoding of disparity, dependence of disparity limits on spatial scale, role of occlusion in binocular depth and surface perception, and motion in 3D. In the case of binocular rivalry, controversies include eye versus stimulus rivalry, role of “top-down” influences on rivalry dynamics, and the interaction of binocular rivalry and stereopsis. Concerning binocular contrast summation, the essay focuses on two representative models that highlight the evolving complexity in this field of study. PMID:20951722

  5. The evolution of vision.

    PubMed

    Gehring, Walter J

    2014-01-01

    In this review, the evolution of vision is retraced from its putative origins in cyanobacteria to humans. Circadian oscillatory clocks, phototropism, and phototaxis require the capability to detect light. Photosensory proteins allow us to reconstruct molecular phylogenetic trees. The evolution of animal eyes leading from an ancestral prototype to highly complex image forming eyes can be deciphered on the basis of evolutionary developmental genetic experiments and comparative genomics. As all bilaterian animals share the same master control gene, Pax6, and the same retinal and pigment cell determination genes, we conclude that the different eye-types originated monophyletically and subsequently diversified by divergent, parallel, or convergent evolution.

  6. Seeing in the dark: vision and visual behaviour in nocturnal bees and wasps.

    PubMed

    Warrant, Eric J

    2008-06-01

    In response to the pressures of predation, parasitism and competition for limited resources, several groups of (mainly) tropical bees and wasps have independently evolved a nocturnal lifestyle. Like their day-active (diurnal) relatives, these insects possess apposition compound eyes, a relatively light-insensitive eye design that is best suited to vision in bright light. Despite this, nocturnal bees and wasps are able to forage at night, with many species capable of flying through a dark and complex forest between the nest and a foraging site, a behaviour that relies heavily on vision and is limited by light intensity. In the two best-studied species - the Central American sweat bee Megalopta genalis (Halictidae) and the Indian carpenter bee Xylocopa tranquebarica (Apidae) - learned visual landmarks are used to guide foraging and homing. Their apposition eyes, however, have only around 30 times greater optical sensitivity than the eyes of their closest diurnal relatives, a fact that is apparently inconsistent with their remarkable nocturnal visual abilities. Moreover, signals generated in the photoreceptors, even though amplified by a high transduction gain, are too noisy and slow to transmit significant amounts of information in dim light. How have nocturnal bees and wasps resolved these paradoxes? Even though this question remains to be answered conclusively, a mounting body of theoretical and experimental evidence suggests that the slow and noisy visual signals generated by the photoreceptors are spatially summed by second-order monopolar cells in the lamina, a process that could dramatically improve visual reliability for the coarser and slower features of the visual world at night.

  7. COLORBLIND VISION

    PubMed Central

    Hecht, Selig; Hsia, Yun

    1947-01-01

    1. Measurements have been made of the dark-adapted foveal threshold of normal and colorblind persons in five parts of the spectrum using a 1° circular test field. 2. Compared to normals, protanopes (red-blinds) show an elevation of the threshold which increases slowly from blue to yellow and rises rapidly thereafter until in the red the threshold is more than ten times as high as normal. Deuteranopes (green-blinds) do not show so high an elevation, their maximum in the green being only about 70 per cent above normal. 3. These threshold elevations correspond to luminosity losses in the spectrum. For the protanope the total loss in the spectrum is nearly one-half of the normal luminosity; for the deuteranope it is nearly two-fifths of normal. 4. Such losses support the idea that colorblindness corresponds to the loss of one of the three receptor systems usually postulated to account for normal color vision. However, the color sensations reported by colorblind persons, especially monocular colorblinds, do not support the idea of a lost or inactivated receptor system. A fresh explanation for colorblindness is called for to reconcile these conflicting kinds of evidence. PMID:18896937

  8. International computer vision directory

    SciTech Connect

    Flora, P.C.

    1986-01-01

    This book contains information on: computerized automation technologies. State-of-the-art computer vision systems for many areas of industrial use are covered. Other topics discussed include the following automated inspection systems; robot/vision systems; vision process control; cameras (vidicon and solid state); vision peripherals and components; and pattern processor.

  9. Two eyes for two purposes: in situ evidence for asymmetric vision in the cockeyed squids Histioteuthis heteropsis and Stigmatoteuthis dofleini.

    PubMed

    Thomas, Kate N; Robison, Bruce H; Johnsen, Sönke

    2017-04-05

    The light environment of the mesopelagic realm of the ocean changes with both depth and viewer orientation, and this has probably driven the high diversity of visual adaptations found among its inhabitants. The mesopelagic 'cockeyed' squids of family Histioteuthidae have unusual eyes, as the left and right eyes are dimorphic in size, shape and sometimes lens pigmentation. This dimorphism may be an adaptation to the two different sources of light in the mesopelagic realm, with the large eye oriented upward to view objects silhouetted against the dim, downwelling sunlight and the small eye oriented slightly downward to view bioluminescent point sources. We used in situ video footage from remotely operated vehicles in the Monterey Submarine Canyon to observe the orientation behaviour of 152 Histioteuthis heteropsis and nine Stigmatoteuthis dofleini We found evidence for upward orientation in the large eye and slightly downward orientation in the small eye, which was facilitated by a tail-up oblique body orientation. We also found that 65% of adult H. heteropsis (n = 69) had yellow pigmentation in the lens of the larger left eye, which may be used to break the counterillumination camouflage of their prey. Finally, we used visual modelling to show that the visual returns provided by increasing eye size are much higher for an upward-oriented eye than for a downward-oriented eye, which may explain the development of this unique visual strategy.This article is part of the themed issue 'Vision in dim light'. © 2017 The Author(s).

  10. (Computer vision and robotics)

    SciTech Connect

    Jones, J.P.

    1989-02-13

    The traveler attended the Fourth Aalborg International Symposium on Computer Vision at Aalborg University, Aalborg, Denmark. The traveler presented three invited lectures entitled, Concurrent Computer Vision on a Hypercube Multicomputer'', The Butterfly Accumulator and its Application in Concurrent Computer Vision on Hypercube Multicomputers'', and Concurrency in Mobile Robotics at ORNL'', and a ten-minute editorial entitled, It Concurrency an Issue in Computer Vision.'' The traveler obtained information on current R D efforts elsewhere in concurrent computer vision.

  11. Restoration of Vision in the pde6β-deficient Dog, a Large Animal Model of Rod-cone Dystrophy

    PubMed Central

    Petit, Lolita; Lhériteau, Elsa; Weber, Michel; Le Meur, Guylène; Deschamps, Jack-Yves; Provost, Nathalie; Mendes-Madeira, Alexandra; Libeau, Lyse; Guihal, Caroline; Colle, Marie-Anne; Moullier, Philippe; Rolling, Fabienne

    2012-01-01

    Defects in the β subunit of rod cGMP phosphodiesterase 6 (PDE6β) are associated with autosomal recessive retinitis pigmentosa (RP), a childhood blinding disease with early retinal degeneration and vision loss. To date, there is no treatment for this pathology. The aim of this preclinical study was to test recombinant adeno-associated virus (AAV)-mediated gene addition therapy in the rod-cone dysplasia type 1 (rcd1) dog, a large animal model of naturally occurring PDE6β deficiency that strongly resembles the human pathology. A total of eight rcd1 dogs were injected subretinally with AAV2/5RK.cpde6β (n = 4) or AAV2/8RK.cpde6β (n = 4). In vivo and post-mortem morphological analysis showed a significant preservation of the retinal structure in transduced areas of both AAV2/5RK.cpde6β- and AAV2/8RK.cpde6β-treated retinas. Moreover, substantial rod-derived electroretinography (ERG) signals were recorded as soon as 1 month postinjection (35% of normal eyes) and remained stable for at least 18 months (the duration of the study) in treated eyes. Rod-responses were undetectable in untreated contralateral eyes. Most importantly, dim-light vision was restored in all treated rcd1 dogs. These results demonstrate for the first time that gene therapy effectively restores long-term retinal function and vision in a large animal model of autosomal recessive rod-cone dystrophy, and provide great promise for human treatment. PMID:22828504

  12. Evolution of Vision

    NASA Astrophysics Data System (ADS)

    Ostrovsky, Mikhail

    The evolution of photoreception, giving rise to eye, offers a kaleidoscopic view on selection acting at both the organ and molecular levels. The molecular level is mainly considered in the lecture. The greatest progress to date has been made in relation to the opsin visual pigments. Opsins appeared before eyes did. Two- and three-dimensional organization for rhodopsin in the rod outer segment disk membrane, as well as molecular mechanisms of visual pigments spectral tuning, photoisomerization and also opsin as a G-protein coupled receptor are considered. Molecular mechanisms of visual pigments spectral tuning, namely switching of chromophore (physiological time scale) and amino acid changes in the chromophore site of opsin (evolutionary time scale) is considered in the lecture. Photoisomerization of rhodopsin chromophore, 11-cis retinal is the only photochemical reaction in vision. The reaction is extemely fast (less that 200 fs) and high efficient (. is 0.65). The rhodopsin photolysis and kinetics of the earlier products appearance, photo- and bathorhodopsin, is considered. It is known that light is not only a carrier of information, but also a risk factor of damage to the eye. This photobiological paradox of vision is mainly due to the nature of rhodopsin chromophore. Photooxidation is the base of the paradox. All factors present in the phototrceptor cells to initiate free-radical photooxidation: photosensitizers, oxygen and substrates of oxidation: lipids and proteins (opsin). That is why photoprotective system of the eye structures appeared in the course of evolution. Three lines of protective system to prevent light damage to the retina and retina pigment epithelium is known: permanent renewal of rod and cone outer segment, powerful antioxidant system and optical media as cut-off filters where the lens is a key component. The molecular mechanisms of light damage to the eye and photoprotective system of the eye is considered in the lecture. The molecular

  13. Chemicals Industry Vision

    SciTech Connect

    none,

    1996-12-01

    Chemical industry leaders articulated a long-term vision for the industry, its markets, and its technology in the groundbreaking 1996 document Technology Vision 2020 - The U.S. Chemical Industry. (PDF 310 KB).

  14. Communicating Your Vision

    ERIC Educational Resources Information Center

    Cartwright, Talula; Baldwin, David

    2006-01-01

    One part of a leader's job is to create commitment to their organization's vision. In order to do this, the leader must communicate the vision effectively. This guidebook suggests many ways to communicate a vision. It also discusses how to deal with a resistant audience and what to do in the event that one as a leader finds themselves resistant.…

  15. Robot Vision Library

    NASA Technical Reports Server (NTRS)

    Howard, Andrew B.; Ansar, Adnan I.; Litwin, Todd E.; Goldberg, Steven B.

    2009-01-01

    The JPL Robot Vision Library (JPLV) provides real-time robot vision algorithms for developers who are not vision specialists. The package includes algorithms for stereo ranging, visual odometry and unsurveyed camera calibration, and has unique support for very wideangle lenses

  16. A child's vision.

    PubMed

    Nye, Christina

    2014-06-01

    Implementing standard vision screening techniques in the primary care practice is the most effective means to detect children with potential vision problems at an age when the vision loss may be treatable. A critical period of vision development occurs in the first few weeks of life; thus, it is imperative that serious problems are detected at this time. Although it is not possible to quantitate an infant's vision, evaluating ocular health appropriately can mean the difference between sight and blindness and, in the case of retinoblastoma, life or death. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Computational approaches to vision

    NASA Technical Reports Server (NTRS)

    Barrow, H. G.; Tenenbaum, J. M.

    1986-01-01

    Vision is examined in terms of a computational process, and the competence, structure, and control of computer vision systems are analyzed. Theoretical and experimental data on the formation of a computer vision system are discussed. Consideration is given to early vision, the recovery of intrinsic surface characteristics, higher levels of interpretation, and system integration and control. A computational visual processing model is proposed and its architecture and operation are described. Examples of state-of-the-art vision systems, which include some of the levels of representation and processing mechanisms, are presented.

  18. Vision and multiple sclerosis.

    PubMed

    Hickman, Simon J; Raoof, Naz; McLean, Rebecca J; Gottlob, Irene

    2014-01-01

    Multiple sclerosis can affect vision in many ways, including optic neuritis, chronic optic neuropathy, retrochiasmal visual field defects, higher order cortical processing, double vision, nystagmus and also by related ocular conditions such as uveitis. There are also side effects from recently introduced multiple sclerosis treatments that can affect vision. This review will discuss all these aspects and how they come together to cause visual symptoms. It will then focus on practical aspects of how to recognise when there is a vision problem in a multiple sclerosis patient and on what treatments are available to improve vision.

  19. Computational approaches to vision

    NASA Technical Reports Server (NTRS)

    Barrow, H. G.; Tenenbaum, J. M.

    1986-01-01

    Vision is examined in terms of a computational process, and the competence, structure, and control of computer vision systems are analyzed. Theoretical and experimental data on the formation of a computer vision system are discussed. Consideration is given to early vision, the recovery of intrinsic surface characteristics, higher levels of interpretation, and system integration and control. A computational visual processing model is proposed and its architecture and operation are described. Examples of state-of-the-art vision systems, which include some of the levels of representation and processing mechanisms, are presented.

  20. Microwave vision for robots

    NASA Technical Reports Server (NTRS)

    Lewandowski, Leon; Struckman, Keith

    1994-01-01

    Microwave Vision (MV), a concept originally developed in 1985, could play a significant role in the solution to robotic vision problems. Originally our Microwave Vision concept was based on a pattern matching approach employing computer based stored replica correlation processing. Artificial Neural Network (ANN) processor technology offers an attractive alternative to the correlation processing approach, namely the ability to learn and to adapt to changing environments. This paper describes the Microwave Vision concept, some initial ANN-MV experiments, and the design of an ANN-MV system that has led to a second patent disclosure in the robotic vision field.

  1. Light and the evolution of vision

    PubMed Central

    Williams, D L

    2016-01-01

    It might seem a little ridiculous to cover the period over which vision evolved, perhaps 1.5 billion years, in only 3000 words. Yet, if we examine the photoreceptor molecules of the most basic eukaryote protists and even before that, in those of prokaryote bacteria and cyanobacteria, we see how similar they are to those of mammalian rod and cone photoreceptor opsins and the photoreceptive molecules of light sensitive ganglion cells. This shows us much with regard the development of vision once these proteins existed, but there is much more to discover about the evolution of even more primitive vision systems. PMID:26541087

  2. Colour vision deficiency.

    PubMed

    Simunovic, M P

    2010-05-01

    Colour vision deficiency is one of the commonest disorders of vision and can be divided into congenital and acquired forms. Congenital colour vision deficiency affects as many as 8% of males and 0.5% of females--the difference in prevalence reflects the fact that the commonest forms of congenital colour vision deficiency are inherited in an X-linked recessive manner. Until relatively recently, our understanding of the pathophysiological basis of colour vision deficiency largely rested on behavioural data; however, modern molecular genetic techniques have helped to elucidate its mechanisms. The current management of congenital colour vision deficiency lies chiefly in appropriate counselling (including career counselling). Although visual aids may be of benefit to those with colour vision deficiency when performing certain tasks, the evidence suggests that they do not enable wearers to obtain normal colour discrimination. In the future, gene therapy remains a possibility, with animal models demonstrating amelioration following treatment.

  3. Acquired color vision deficiency.

    PubMed

    Simunovic, Matthew P

    2016-01-01

    Acquired color vision deficiency occurs as the result of ocular, neurologic, or systemic disease. A wide array of conditions may affect color vision, ranging from diseases of the ocular media through to pathology of the visual cortex. Traditionally, acquired color vision deficiency is considered a separate entity from congenital color vision deficiency, although emerging clinical and molecular genetic data would suggest a degree of overlap. We review the pathophysiology of acquired color vision deficiency, the data on its prevalence, theories for the preponderance of acquired S-mechanism (or tritan) deficiency, and discuss tests of color vision. We also briefly review the types of color vision deficiencies encountered in ocular disease, with an emphasis placed on larger or more detailed clinical investigations. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. How to assess vision.

    PubMed

    Marsden, Janet

    2016-09-21

    Rationale and key points An objective assessment of the patient's vision is important to assess variation from 'normal' vision in acute and community settings, to establish a baseline before examination and treatment in the emergency department, and to assess any changes during ophthalmic outpatient appointments. » Vision is one of the essential senses that permits people to make sense of the world. » Visual assessment does not only involve measuring central visual acuity, it also involves assessing the consequences of reduced vision. » Assessment of vision in children is crucial to identify issues that might affect vision and visual development, and to optimise lifelong vision. » Untreatable loss of vision is not an inevitable consequence of ageing. » Timely and repeated assessment of vision over life can reduce the incidence of falls, prevent injury and optimise independence. Reflective activity 'How to' articles can help update you practice and ensure it remains evidence based. Apply this article to your practice. Reflect on and write a short account of: 1. How this article might change your practice when assessing people holistically. 2. How you could use this article to educate your colleagues in the assessment of vision.

  5. Mathematical leadership vision.

    PubMed

    Hamburger, Y A

    2000-11-01

    This article is an analysis of a new type of leadership vision, the kind of vision that is becoming increasingly pervasive among leaders in the modern world. This vision appears to offer a new horizon, whereas, in fact it delivers to its target audience a finely tuned version of the already existing ambitions and aspirations of the target audience. The leader, with advisors, has examined the target audience and has used the results of extensive research and statistical methods concerning the group to form a picture of its members' lifestyles and values. On the basis of this information, the leader has built a "vision." The vision is intended to create an impression of a charismatic and transformational leader when, in fact, it is merely a response. The systemic, arithmetic, and statistical methods employed in this operation have led to the coining of the terms mathematical leader and mathematical vision.

  6. FPGA Vision Data Architecture

    NASA Technical Reports Server (NTRS)

    Morfopoulos, Arin C.; Pham, Thang D.

    2013-01-01

    JPL has produced a series of FPGA (field programmable gate array) vision algorithms that were written with custom interfaces to get data in and out of each vision module. Each module has unique requirements on the data interface, and further vision modules are continually being developed, each with their own custom interfaces. Each memory module had also been designed for direct access to memory or to another memory module.

  7. Vision, reanimated and reimagined.

    PubMed

    Edelman, Shimon

    2012-01-01

    The publication in 1982 of David Marr's Vision has delivered a singular boost and a course correction to the science of vision. Thirty years later, cognitive science is being transformed by the new ways of thinking about what it is that the brain computes, how it does that, and, most importantly, why cognition requires these computations and not others. This ongoing process still owes much of its impetus and direction to the sound methodology, engaging style, and unique voice of Marr's Vision.

  8. Vision Changes in Space

    NASA Image and Video Library

    This Human Research Program 'Research to Outreach' video featuring NASA Clinical Translational Scientist Jennifer Fogarty explains the risk of vision impairment both during and after spaceflight, i...

  9. Artificial human vision camera

    NASA Astrophysics Data System (ADS)

    Goudou, J.-F.; Maggio, S.; Fagno, M.

    2014-10-01

    In this paper we present a real-time vision system modeling the human vision system. Our purpose is to inspire from human vision bio-mechanics to improve robotic capabilities for tasks such as objects detection and tracking. This work describes first the bio-mechanical discrepancies between human vision and classic cameras and the retinal processing stage that takes place in the eye, before the optic nerve. The second part describes our implementation of these principles on a 3-camera optical, mechanical and software model of the human eyes and associated bio-inspired attention model.

  10. Biomimetic machine vision system.

    PubMed

    Harman, William M; Barrett, Steven F; Wright, Cameron H G; Wilcox, Michael

    2005-01-01

    Real-time application of digital imaging for use in machine vision systems has proven to be prohibitive when used within control systems that employ low-power single processors without compromising the scope of vision or resolution of captured images. Development of a real-time machine analog vision system is the focus of research taking place at the University of Wyoming. This new vision system is based upon the biological vision system of the common house fly. Development of a single sensor is accomplished, representing a single facet of the fly's eye. This new sensor is then incorporated into an array of sensors capable of detecting objects and tracking motion in 2-D space. This system "preprocesses" incoming image data resulting in minimal data processing to determine the location of a target object. Due to the nature of the sensors in the array, hyperacuity is achieved thereby eliminating resolutions issues found in digital vision systems. In this paper, we will discuss the biological traits of the fly eye and the specific traits that led to the development of this machine vision system. We will also discuss the process of developing an analog based sensor that mimics the characteristics of interest in the biological vision system. This paper will conclude with a discussion of how an array of these sensors can be applied toward solving real-world machine vision issues.

  11. Color vision deficiencies

    NASA Astrophysics Data System (ADS)

    Vannorren, D.

    1982-04-01

    Congenital and acquired color vision defects are described in the context of physiological data. Light sources, photometry, color systems and test methods are described. A list of medicines is also presented. The practical social consequences of color vision deficiencies are discussed.

  12. Why Vision 2020?

    ERIC Educational Resources Information Center

    Hinckley, June

    2000-01-01

    Discusses changes in technology, information, and people and the impact on music programs. The Vision 2020 project focuses on the future of music education. Addresses the events that created Vision 2020. Includes "The Housewright Declaration," a summarization of agreements from the Housewright Symposium on the Future of Music Education. (CMK)

  13. A Poet's Vision.

    ERIC Educational Resources Information Center

    Marshall, Suzanne; Newman, Dan

    1997-01-01

    Describes a series of activities to help middle school students develop an artist's vision and then convey that vision through poetry. Describes how lessons progress from looking at concrete objects to observations of settings and characters, gradually adding memory and imagination to direct observation, and finishing with revision. Notes that…

  14. INSIGHT: Vision & Leadership, 2002.

    ERIC Educational Resources Information Center

    McGraw, Tammy, Ed.

    2002-01-01

    This publication focuses on promising new and emerging technologies and what they might mean to the future of K-12 schools. Half of the volume contains articles devoted in some way to "Vision," and articles in the other half are under the heading of "Leadership." Contents in the "Vision" section include: "The…

  15. Degas: Vision and Perception.

    ERIC Educational Resources Information Center

    Kendall, Richard

    1988-01-01

    The art of Edgar Degas is discussed in relation to his impaired vision, including amblyopia, later blindness in one eye, corneal scarring, and photophobia. Examined are ways in which Degas compensated for vision problems, and dominant themes of his art such as the process of perception and spots of brilliant light. (Author/JDD)

  16. New Term, New Vision?

    ERIC Educational Resources Information Center

    Ravenhall, Mark

    2011-01-01

    During the affluent noughties it was sometimes said of government that it had "more visions than Mystic Meg and more pilots than British Airways". In 2011, the pilots, the pathfinders, the new initiatives are largely gone--implementation is the name of the game--but the visions remain. The latest one, as it affects adult learners, is in…

  17. New Term, New Vision?

    ERIC Educational Resources Information Center

    Ravenhall, Mark

    2011-01-01

    During the affluent noughties it was sometimes said of government that it had "more visions than Mystic Meg and more pilots than British Airways". In 2011, the pilots, the pathfinders, the new initiatives are largely gone--implementation is the name of the game--but the visions remain. The latest one, as it affects adult learners, is in…

  18. Robust computational vision

    NASA Astrophysics Data System (ADS)

    Schunck, Brian G.

    1993-08-01

    This paper presents a paradigm for formulating reliable machine vision algorithms using methods from robust statistics. Machine vision is the process of estimating features from images by fitting a model to visual data. Vision research has produced an understanding of the physics and mathematics of visual processes. The fact that computer graphics programs can produce realistic renderings of artificial scenes indicates that our understanding of vision processes must be quite good. The premise of this paper is that the problem in applying computer vision in realistic scenes is not the fault of the theory of vision. We have good models for visual phenomena, but can do a better job of applying the models to images. Our understanding of vision must be used in computations that are robust to the kinds of errors that occur in visual signals. This paper argues that vision algorithms should be formulated using methods from robust regression. The nature of errors in visual signals is discussed, and a prescription for formulating robust algorithms is described. To illustrate the concepts, robust methods have been applied to several problems: surface reconstruction, dynamic stereo, image flow estimation, and edge detection.

  19. Synthesized night vision goggle

    NASA Astrophysics Data System (ADS)

    Zhou, Haixian

    2000-06-01

    A Synthesized Night Vision Goggle that will be described int his paper is a new type of night vision goggle with multiple functions. It consists of three parts: main observing system, picture--superimposed system (or Cathode Ray Tube system) and Charge-Coupled Device system.

  20. Near Vision Test for Adults

    MedlinePlus

    ... Eye Emergencies How to Jump Start a Car Battery Safely Electronic Screens and Your Eyes Nutrition and ... External Resources The Cost of Vision Problems The Future of Vision Vision Problems in the U.S. Healthy ...

  1. Panoramic stereo sphere vision

    NASA Astrophysics Data System (ADS)

    Feng, Weijia; Zhang, Baofeng; Röning, Juha; Zong, Xiaoning; Yi, Tian

    2013-01-01

    Conventional stereo vision systems have a small field of view (FOV) which limits their usefulness for certain applications. While panorama vision is able to "see" in all directions of the observation space, scene depth information is missed because of the mapping from 3D reference coordinates to 2D panoramic image. In this paper, we present an innovative vision system which builds by a special combined fish-eye lenses module, and is capable of producing 3D coordinate information from the whole global observation space and acquiring no blind area 360°×360° panoramic image simultaneously just using single vision equipment with one time static shooting. It is called Panoramic Stereo Sphere Vision (PSSV). We proposed the geometric model, mathematic model and parameters calibration method in this paper. Specifically, video surveillance, robotic autonomous navigation, virtual reality, driving assistance, multiple maneuvering target tracking, automatic mapping of environments and attitude estimation are some of the applications which will benefit from PSSV.

  2. Light Vision Color

    NASA Astrophysics Data System (ADS)

    Valberg, Arne

    2005-04-01

    Light Vision Color takes a well-balanced, interdisciplinary approach to our most important sensory system. The book successfully combines basics in vision sciences with recent developments from different areas such as neuroscience, biophysics, sensory psychology and philosophy. Originally published in 1998 this edition has been extensively revised and updated to include new chapters on clinical problems and eye diseases, low vision rehabilitation and the basic molecular biology and genetics of colour vision. Takes a broad interdisciplinary approach combining basics in vision sciences with the most recent developments in the area Includes an extensive list of technical terms and explanations to encourage student understanding Successfully brings together the most important areas of the subject in to one volume

  3. (Computer) Vision without Sight

    PubMed Central

    Manduchi, Roberto; Coughlan, James

    2012-01-01

    Computer vision holds great promise for helping persons with blindness or visual impairments (VI) to interpret and explore the visual world. To this end, it is worthwhile to assess the situation critically by understanding the actual needs of the VI population and which of these needs might be addressed by computer vision. This article reviews the types of assistive technology application areas that have already been developed for VI, and the possible roles that computer vision can play in facilitating these applications. We discuss how appropriate user interfaces are designed to translate the output of computer vision algorithms into information that the user can quickly and safely act upon, and how system-level characteristics affect the overall usability of an assistive technology. Finally, we conclude by highlighting a few novel and intriguing areas of application of computer vision to assistive technology. PMID:22815563

  4. Color vision and dentistry.

    PubMed

    Wasson, W; Schuman, N

    1992-05-01

    Color vision is a critical component of restorative and esthetic dentistry, but dentists, as a group, do not have their color vision tested at any time during their careers. A study was undertaken to ascertain the color-vision status of practicing dental personnel at the University of Tennessee, College of Dentistry. One hundred fifty individuals, 75 men and 75 women, were screened. The results corroborated the existing medical data for the general population. It was found that 9.3% of the men and none of the women exhibited color-vision defect. Since most dentists are male, this study demonstrates an area of potential weakness for some practitioners. Once a color-vision problem is found, it is simple to remedy by employing a team approach to shade matching or mechanical means of matching shades (by the practitioner). No ethnic or racial distinctions were detected, although these have been reported in other studies.

  5. Machine vision is not computer vision

    NASA Astrophysics Data System (ADS)

    Batchelor, Bruce G.; Charlier, Jean-Ray

    1998-10-01

    The identity of Machine Vision as an academic and practical subject of study is asserted. In particular, the distinction between Machine Vision on the one hand and Computer Vision, Digital Image Processing, Pattern Recognition and Artificial Intelligence on the other is emphasized. The article demonstrates through four cases studies that the active involvement of a person who is sensitive to the broad aspects of vision system design can avoid disaster and can often achieve a successful machine that would not otherwise have been possible. This article is a transcript of the key- note address presented at the conference. Since the proceedings are prepared and printed before the conference, it is not possible to include a record of the response to this paper made by the delegates during the round-table discussion. It is hoped to collate and disseminate these via the World Wide Web after the event. (A link will be provided at http://bruce.cs.cf.ac.uk/bruce/index.html.).

  6. Literature and information in vision care and vision science.

    PubMed

    Goss, David A

    2008-11-01

    The explosion of information in vision care and vision science makes keeping up with the literature and information in the field challenging. This report examines the nature of literature and information in vision care and vision science. A variety of topics are discussed, including the general nature of scientific and clinical journals, journals in vision science and vision care, resources available for searches for literature and information, and issues involved in the evaluation of journals and other information sources. Aspects of the application of citation analysis to vision care and vision science are reviewed, and a new citation analysis of a leading textbook in vision care (Borish's Clinical Refraction) is presented. This report is directed toward anyone who wants to be more informed about the literature of vision care and vision science, whether they are students, clinicians, educators, or librarians.

  7. Dim light at night disturbs the daily sleep-wake cycle in the rat.

    PubMed

    Stenvers, Dirk Jan; van Dorp, Rick; Foppen, Ewout; Mendoza, Jorge; Opperhuizen, Anne-Loes; Fliers, Eric; Bisschop, Peter H; Meijer, Johanna H; Kalsbeek, Andries; Deboer, Tom

    2016-10-20

    Exposure to light at night (LAN) is associated with insomnia in humans. Light provides the main input to the master clock in the hypothalamic suprachiasmatic nucleus (SCN) that coordinates the sleep-wake cycle. We aimed to develop a rodent model for the effects of LAN on sleep. Therefore, we exposed male Wistar rats to either a 12 h light (150-200lux):12 h dark (LD) schedule or a 12 h light (150-200 lux):12 h dim white light (5 lux) (LDim) schedule. LDim acutely decreased the amplitude of daily rhythms of REM and NREM sleep, with a further decrease over the following days. LDim diminished the rhythms of 1) the circadian 16-19 Hz frequency domain within the NREM sleep EEG, and 2) SCN clock gene expression. LDim also induced internal desynchronization in locomotor activity by introducing a free running rhythm with a period of ~25 h next to the entrained 24 h rhythm. LDim did not affect body weight or glucose tolerance. In conclusion, we introduce the first rodent model for disturbed circadian control of sleep due to LAN. We show that internal desynchronization is possible in a 24 h L:D cycle which suggests that a similar desynchronization may explain the association between LAN and human insomnia.

  8. Mice exposed to dim light at night exaggerate inflammatory responses to lipopolysaccharide.

    PubMed

    Fonken, Laura K; Weil, Zachary M; Nelson, Randy J

    2013-11-01

    The mammalian circadian system regulates many physiological functions including inflammatory responses. Appropriately timed light information is essential for maintaining circadian organization. Over the past ∼120 years, urbanization and the widespread adoption of electric lights have dramatically altered lighting environments. Exposure to light at night (LAN) is pervasive in modern society and disrupts core circadian clock mechanisms. Because microglia are the resident macrophages in the brain and macrophages contain intrinsic circadian clocks, we hypothesized that chronic exposure to LAN would alter microglia cytokine expression and sickness behavior following LPS administration. Exposure to 4 weeks of dim LAN elevated inflammatory responses in mice. Mice exposed to dimly lit, as compared to dark, nights exaggerated changes in body temperature and elevated microglia pro-inflammatory cytokine expression following LPS administration. Furthermore, dLAN mice had a prolonged sickness response following the LPS challenge. Mice exposed to dark or dimly lit nights had comparable sickness behavior directly following the LPS injection; however, dLAN mice showed greater reductions in locomotor activity, increased anorectic behavior, and increased weight loss than mice maintained in dark nights 24h post-LPS injection. Overall, these data suggest that chronic exposure to even very low levels of light pollution may alter inflammatory responses. These results may have important implications for humans and other urban dwelling species that commonly experience nighttime light exposure. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Astrobiological implications of dim light phototrophy in deep-sea red clays

    NASA Astrophysics Data System (ADS)

    Das, Anindita; Singh, Tanya; LokaBharathi, P. A.; Dhakephalkar, Prashant K.; Mallik, Sweta; Kshirsagar, Pranav R.; Khadge, N. H.; Nath, B. Nagender; Bhattacharya, Satadru; Dagar, Aditya Kumar; Kaur, Prabhjot; Ray, Dwijesh; Shukla, Anil D.; Fernandes, Christabelle E. G.; Fernandes, Sheryl O.; Thomas, Tresa Remya A.; Mamatha, s. S.; Mourya, Babu Shashikant; Meena, Ram Murti

    2017-02-01

    Red clays of Central Indian Basin (CIB) under influence of trace of Rodriguez Triple Junction exhibited chemoautotrophy, low temperature hydrothermal alterations and photoautotrophic potential. Seamount flank TVBC-08, hosting such signatures revealed dominance of aerobic anoxygenic phototroph Erythrobacter, with 93% of total 454 pyrosequencing tags. Subsequently, enrichments for both aerobic (Erythrobacter) and anaerobic anoxygenic phototrophs (green and purple sulphur bacteria) under red and white LED light illumination, with average irradiance 30.66 W m-2, were attempted for three red-clay sediment cores. Successful enrichments were obtained after incubation for c.a. 120 days at 4°± 2 °C and 25°± 2 °C, representing ambient psychrophilic and low temperature hydrothermal alteration conditions respectively. During hydrothermal cooling, a microbial succession from anaerobic chemolithotrophy to oxygenic photoautotrophy through anaerobic/aerobic anoxygenic phototrophic microbes is indicated. Spectral absorbance patterns of the methanol extracted cell pellets showed peaks corresponding to metal sulphide precipitations, the Soret band of chlorosome absorbance by photosystem II and absence of peaks at Qy transition band. Dendritic nano-structures of metal sulphides are common in these sediments and are comparable with other sulphidic paleo-marine Martian analogues. Significant blue and redshifts have been observed for the experimental samples relative to the un-inoculated medium. These observations indicate the propensity of metal-sulphide deposits contributing to chemiluminiscence supporting the growth of phototrophs at least partially, in the otherwise dark abyss. The effects of other geothermal heat and light sources are also under further consideration. The potential of phototrophic microbial cells to exhibit Doppler shift in absorbance patterns is significant towards understanding planetary microbial habitability. Planetary desiccation could considerably influence Doppler effects and consequently spectral detection techniques exo-planetary microbial life.

  10. Chronic dim light at night provokes reversible depression-like phenotype: possible role for TNF.

    PubMed

    Bedrosian, T A; Weil, Z M; Nelson, R J

    2013-08-01

    The prevalence of major depression has increased in recent decades and women are twice as likely as men to develop the disorder. Recent environmental changes almost certainly have a role in this phenomenon, but a complete set of contributors remains unspecified. Exposure to artificial light at night (LAN) has surged in prevalence during the past 50 years, coinciding with rising rates of depression. Chronic exposure to LAN is linked to increased risk of breast cancer, obesity and mood disorders, although the relationship to mood is not well characterized. In this study, we investigated the effects of chronic exposure to 5 lux LAN on depression-like behaviors in female hamsters. Using this model, we also characterized hippocampal brain-derived neurotrophic factor expression and hippocampal dendritic morphology, and investigated the reversibility of these changes 1, 2 or 4 weeks following elimination of LAN. Furthermore, we explored the mechanism of action, focusing on hippocampal proinflammatory cytokines given their dual role in synaptic plasticity and the pathogenesis of depression. Using reverse transcription-quantitative PCR, we identified a reversible increase in hippocampal tumor necrosis factor (TNF), but not interleukin-1β, mRNA expression in hamsters exposed to LAN. Direct intracerebroventricular infusion of a dominant-negative inhibitor of soluble TNF, XPro1595, prevented the development of depression-like behavior under LAN, but had no effect on dendritic spine density in the hippocampus. These results indicate a partial role for TNF in the reversible depression-like phenotype observed under chronic dim LAN. Recent environmental changes, such as LAN exposure, may warrant more attention as possible contributors to rising rates of mood disorders.

  11. Dim light at night disturbs the daily sleep-wake cycle in the rat

    PubMed Central

    Jan Stenvers, Dirk; van Dorp, Rick; Foppen, Ewout; Mendoza, Jorge; Opperhuizen, Anne-Loes; Fliers, Eric; Bisschop, Peter H.; Meijer, Johanna H.; Kalsbeek, Andries; Deboer, Tom

    2016-01-01

    Exposure to light at night (LAN) is associated with insomnia in humans. Light provides the main input to the master clock in the hypothalamic suprachiasmatic nucleus (SCN) that coordinates the sleep-wake cycle. We aimed to develop a rodent model for the effects of LAN on sleep. Therefore, we exposed male Wistar rats to either a 12 h light (150–200lux):12 h dark (LD) schedule or a 12 h light (150–200 lux):12 h dim white light (5 lux) (LDim) schedule. LDim acutely decreased the amplitude of daily rhythms of REM and NREM sleep, with a further decrease over the following days. LDim diminished the rhythms of 1) the circadian 16–19 Hz frequency domain within the NREM sleep EEG, and 2) SCN clock gene expression. LDim also induced internal desynchronization in locomotor activity by introducing a free running rhythm with a period of ~25 h next to the entrained 24 h rhythm. LDim did not affect body weight or glucose tolerance. In conclusion, we introduce the first rodent model for disturbed circadian control of sleep due to LAN. We show that internal desynchronization is possible in a 24 h L:D cycle which suggests that a similar desynchronization may explain the association between LAN and human insomnia. PMID:27762290

  12. Astrobiological implications of dim light phototrophy in deep-sea red clays.

    PubMed

    Das, Anindita; Singh, Tanya; LokaBharathi, P A; Dhakephalkar, Prashant K; Mallik, Sweta; Kshirsagar, Pranav R; Khadge, N H; Nath, B Nagender; Bhattacharya, Satadru; Dagar, Aditya Kumar; Kaur, Prabhjot; Ray, Dwijesh; Shukla, Anil D; Fernandes, Christabelle E G; Fernandes, Sheryl O; Thomas, Tresa Remya A; S S, Mamatha; Mourya, Babu Shashikant; Meena, Ram Murti

    2017-02-01

    Red clays of Central Indian Basin (CIB) under influence of trace of Rodriguez Triple Junction exhibited chemoautotrophy, low temperature hydrothermal alterations and photoautotrophic potential. Seamount flank TVBC-08, hosting such signatures revealed dominance of aerobic anoxygenic phototroph Erythrobacter, with 93% of total 454 pyrosequencing tags. Subsequently, enrichments for both aerobic (Erythrobacter) and anaerobic anoxygenic phototrophs (green and purple sulphur bacteria) under red and white LED light illumination, with average irradiance 30.66Wm(-2), were attempted for three red-clay sediment cores. Successful enrichments were obtained after incubation for c.a. 120 days at 4°± 2°C and 25°± 2°C, representing ambient psychrophilic and low temperature hydrothermal alteration conditions respectively. During hydrothermal cooling, a microbial succession from anaerobic chemolithotrophy to oxygenic photoautotrophy through anaerobic/aerobic anoxygenic phototrophic microbes is indicated. Spectral absorbance patterns of the methanol extracted cell pellets showed peaks corresponding to metal sulphide precipitations, the Soret band of chlorosome absorbance by photosystem II and absence of peaks at Qy transition band. Dendritic nano-structures of metal sulphides are common in these sediments and are comparable with other sulphidic paleo-marine Martian analogues. Significant blue and redshifts have been observed for the experimental samples relative to the un-inoculated medium. These observations indicate the propensity of metal-sulphide deposits contributing to chemiluminiscence supporting the growth of phototrophs at least partially, in the otherwise dark abyss. The effects of other geothermal heat and light sources are also under further consideration. The potential of phototrophic microbial cells to exhibit Doppler shift in absorbance patterns is significant towards understanding planetary microbial habitability. Planetary desiccation could considerably influence Doppler effects and consequently spectral detection techniques exo-planetary microbial life.

  13. Vision and Driving

    PubMed Central

    Owsley, Cynthia; McGwin, Gerald

    2010-01-01

    Driving is the primary means of personal travel in many countries and is relies heavily on vision for its successful execution. Research over the past few decades has addressed the role of vision in driver safety (motor vehicle collision involvement) and in driver performance (both on-road and using interactive simulators in the laboratory). Here we critically review what is currently known about the role of various aspects of visual function in driving. We also discuss translational research issues on vision screening for licensure and re-licensure and rehabilitation of visually impaired persons who want to drive. PMID:20580907

  14. Clinical colour vision tests.

    PubMed

    Dain, Stephen J

    2004-07-01

    The structure and function of the available and significant clinical colour vision tests are reviewed in the light of the needs in the clinical examination of congenital and acquired colour vision deficiencies. The tests are grouped and described as pseudo-isochromatic plates, arrangement tests, matching tests and vocational tests. The colorimetric constructions of the test types are described and the efficiency of their performance and usefulness discussed. Recommendations are made for basic and extended test batteries, when examining of congenital and acquired colour vision deficiencies in the consulting room.

  15. Stereo vision and strabismus.

    PubMed

    Read, J C A

    2015-02-01

    Binocular stereopsis, or stereo vision, is the ability to derive information about how far away objects are, based solely on the relative positions of the object in the two eyes. It depends on both sensory and motor abilities. In this review, I briefly outline some of the neuronal mechanisms supporting stereo vision, and discuss how these are disrupted in strabismus. I explain, in some detail, current methods of assessing stereo vision and their pros and cons. Finally, I review the evidence supporting the clinical importance of such measurements.

  16. Stereo vision and strabismus

    PubMed Central

    Read, J C A

    2015-01-01

    Binocular stereopsis, or stereo vision, is the ability to derive information about how far away objects are, based solely on the relative positions of the object in the two eyes. It depends on both sensory and motor abilities. In this review, I briefly outline some of the neuronal mechanisms supporting stereo vision, and discuss how these are disrupted in strabismus. I explain, in some detail, current methods of assessing stereo vision and their pros and cons. Finally, I review the evidence supporting the clinical importance of such measurements. PMID:25475234

  17. The role of vision processing in prosthetic vision.

    PubMed

    Barnes, Nick; He, Xuming; McCarthy, Chris; Horne, Lachlan; Kim, Junae; Scott, Adele; Lieby, Paulette

    2012-01-01

    Prosthetic vision provides vision which is reduced in resolution and dynamic range compared to normal human vision. This comes about both due to residual damage to the visual system from the condition that caused vision loss, and due to limitations of current technology. However, even with limitations, prosthetic vision may still be able to support functional performance which is sufficient for tasks which are key to restoring independent living and quality of life. Here vision processing can play a key role, ensuring that information which is critical to the performance of key tasks is available within the capability of the available prosthetic vision. In this paper, we frame vision processing for prosthetic vision, highlight some key areas which present problems in terms of quality of life, and present examples where vision processing can help achieve better outcomes.

  18. [Comparison study between biological vision and computer vision].

    PubMed

    Liu, W; Yuan, X G; Yang, C X; Liu, Z Q; Wang, R

    2001-08-01

    The development and bearing of biology vision in structure and mechanism were discussed, especially on the aspects including anatomical structure of biological vision, tentative classification of reception field, parallel processing of visual information, feedback and conformity effect of visual cortical, and so on. The new advance in the field was introduced through the study of the morphology of biological vision. Besides, comparison between biological vision and computer vision was made, and their similarities and differences were pointed out.

  19. Cataract Vision Simulator

    MedlinePlus

    ... Stories Español Eye Health / Eye Health A-Z Cataracts Sections What Are Cataracts? Cataract Symptoms Who Is ... Pictures and Videos: What Do Cataracts Look Like? Cataract Vision Simulator Jun. 11, 2014 How do cataracts ...

  20. Robonaut 2 Vision Testing

    NASA Image and Video Library

    2012-04-30

    ISS031-E-031698 (30 April 2012) --- Controlled by teams on the ground, Robonaut 2 humanoid robot uses a task board during a head and vision check out in the Destiny laboratory of the International Space Station.

  1. Kids' Quest: Vision Impairment

    MedlinePlus

    ... most important job. Return to Steps World-Wide Web Search Kids Health: What is Vision Impairment What ... for the Blind (AFB) created the Braille Bug web site to teach sighted children about braille, and ...

  2. Impairments to Vision

    MedlinePlus

    ... scotoma" right where you're looking. Glaucoma and Retinitis Pigmentosa Ring or Donut Scotoma Left Field Homonymous Hemianopia Although very different diseases, both glaucoma and retinitis pigmentosa (RP) cause a loss of side vision, leading ...

  3. Vision and Motion Pictures.

    ERIC Educational Resources Information Center

    Grambo, Gregory

    1998-01-01

    Presents activities on persistence of vision that involve students in a hands-on approach to the study of early methods of creating motion pictures. Students construct flip books, a Zoetrope, and an early movie machine. (DDR)

  4. Introduction To Color Vision

    NASA Astrophysics Data System (ADS)

    Thorell, Lisa G.

    1983-08-01

    Several human cognitive studies have reported that color facilitates certain learning, memory and search tasks. Consideration of the color-opponent organization of human color vision and the spatial modulation transfer function for color suggests several simple sensory explanations.

  5. Computer Vision Syndrome.

    PubMed

    Randolph, Susan A

    2017-07-01

    With the increased use of electronic devices with visual displays, computer vision syndrome is becoming a major public health issue. Improving the visual status of workers using computers results in greater productivity in the workplace and improved visual comfort.

  6. Retinal Detachment Vision Simulator

    MedlinePlus

    ... is cataract surgery different for someone with high myopia? Oct 01, 2015 Can I Fly with Central ... for Early Alzheimer’s Detection? Aug 08, 2016 Eye Exercises May Improve Vision Around Blind Spot Sep 29, ...

  7. Home vision tests

    MedlinePlus

    ... testing. AMSLER GRID TEST This test helps detect macular degeneration . This is a disease that causes blurred vision, ... exam. People who are at risk of developing macular degeneration may be told by their ophthalmologist to perform ...

  8. Rhetorical Visions of Unmarried Mothers.

    ERIC Educational Resources Information Center

    Endres, Thomas G.

    1989-01-01

    Examines the symbolic reality of unmarried mothers using Bormann's fantasy theme analysis and Q-methodology. Identifies three rhetorical visions with a dramatistic humanistic analysis produced by and about unmarried mothers: the Down and Out Vision, the Making the Best Vision, and the Yummie Vision. (MS)

  9. OH Vision Test

    NASA Image and Video Library

    2014-06-03

    ISS040-E-006739 (3 June 2014) --- European Space Agency astronaut Alexander Gerst, Expedition 40 flight engineer, uses the Optical Coherence Tomography (OCT) camera during an Ocular Health (OH) vision test in the Harmony node of the International Space Station. The OH experiment observes and seeks to understand vision changes during long-term space missions. NASA astronaut Steve Swanson (left), Expedition 40 commander, assists Gerst.

  10. The vision trap.

    PubMed

    Langeler, G H

    1992-01-01

    At Mentor Graphics Corporation, Gerry Langeler was the executive responsible for vision, and vision, he discovered, has the power to weaken a strong company. Mentor helped to invent design-automation electronics in the early 1980s, and by the end of the decade, it dominated the industry. In its early days, fighting to survive, Mentor's motto was Build Something People Will Buy. Then when clear competition emerged in the form of Daisy Systems, a startup that initially outsold Mentor, the watchword became Beat Daisy. Both "visions" were pragmatic and immediate. They gave Mentor a sense of purpose as it developed its products and gathered momentum. Once Daisy was beaten, however, company vision began to self-inflate. As Mentor grew more and more successful, Langeler formulated vision statements that were more and more ambitious, grand, and inspirational. The company traded its gritty determination to survive for a dream of future glory. The once explicit call for effective action became a fervid cry for abstract perfection. The first step was Six Boxes, a transitional vision that combined goals for success in six business areas with grandiose plans to compete with IBM at the level of billion-dollar revenues. From there, vision stepped up to the 10X Imperative, a quality-improvement program that focused on arbitrary goals and measures that were, in fact, beyond the company's control. The last escalation came when Mentor Graphics decided to Change the Way the World Designs. The company had stopped making product and was making poetry. Finally, in 1991, after six years of increasing self-infatuation, Mentor hit a wall of decreasing indicators. Langeler, who had long since begun to doubt the value of abstract visions, reinstated Build Something People Will Buy. And Mentor was back to basics, a sense of purpose back to its workplace.

  11. Synthetic Vision Systems

    NASA Technical Reports Server (NTRS)

    Prinzel, L.J.; Kramer, L.J.

    2009-01-01

    A synthetic vision system is an aircraft cockpit display technology that presents the visual environment external to the aircraft using computer-generated imagery in a manner analogous to how it would appear to the pilot if forward visibility were not restricted. The purpose of this chapter is to review the state of synthetic vision systems, and discuss selected human factors issues that should be considered when designing such displays.

  12. Vision and visual navigation in nocturnal insects.

    PubMed

    Warrant, Eric; Dacke, Marie

    2011-01-01

    With their highly sensitive visual systems, nocturnal insects have evolved a remarkable capacity to discriminate colors, orient themselves using faint celestial cues, fly unimpeded through a complicated habitat, and navigate to and from a nest using learned visual landmarks. Even though the compound eyes of nocturnal insects are significantly more sensitive to light than those of their closely related diurnal relatives, their photoreceptors absorb photons at very low rates in dim light, even during demanding nocturnal visual tasks. To explain this apparent paradox, it is hypothesized that the necessary bridge between retinal signaling and visual behavior is a neural strategy of spatial and temporal summation at a higher level in the visual system. Exactly where in the visual system this summation takes place, and the nature of the neural circuitry that is involved, is currently unknown but provides a promising avenue for future research.

  13. Biofeedback for Better Vision

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Biofeedtrac, Inc.'s Accommotrac Vision Trainer, invented by Dr. Joseph Trachtman, is based on vision research performed by Ames Research Center and a special optometer developed for the Ames program by Stanford Research Institute. In the United States, about 150 million people are myopes (nearsighted), who tend to overfocus when they look at distant objects causing blurry distant vision, or hyperopes (farsighted), whose vision blurs when they look at close objects because they tend to underfocus. The Accommotrac system is an optical/electronic system used by a doctor as an aid in teaching a patient how to contract and relax the ciliary body, the focusing muscle. The key is biofeedback, wherein the patient learns to control a bodily process or function he is not normally aware of. Trachtman claims a 90 percent success rate for correcting, improving or stopping focusing problems. The Vision Trainer has also proved effective in treating other eye problems such as eye oscillation, cross eyes, and lazy eye and in professional sports to improve athletes' peripheral vision and reaction time.

  14. Agile automated vision

    NASA Astrophysics Data System (ADS)

    Fandrich, Juergen; Schmitt, Lorenz A.

    1994-11-01

    The microelectronic industry is a protagonist in driving automated vision to new paradigms. Today semiconductor manufacturers use vision systems quite frequently in their fabs in the front-end process. In fact, the process depends on reliable image processing systems. In the back-end process, where ICs are assembled and packaged, today vision systems are only partly used. But in the next years automated vision will become compulsory for the back-end process as well. Vision will be fully integrated into every IC package production machine to increase yields and reduce costs. Modem high-speed material processing requires dedicated and efficient concepts in image processing. But the integration of various equipment in a production plant leads to unifying handling of data flow and interfaces. Only agile vision systems can act with these contradictions: fast, reliable, adaptable, scalable and comprehensive. A powerful hardware platform is a unneglectable requirement for the use of advanced and reliable, but unfortunately computing intensive image processing algorithms. The massively parallel SIMD hardware product LANTERN/VME supplies a powerful platform for existing and new functionality. LANTERN/VME is used with a new optical sensor for IC package lead inspection. This is done in 3D, including horizontal and coplanarity inspection. The appropriate software is designed for lead inspection, alignment and control tasks in IC package production and handling equipment, like Trim&Form, Tape&Reel and Pick&Place machines.

  15. Color vision testing.

    PubMed

    Melamud, Alex; Hagstrom, Stephanie; Traboulsi, Elias

    2004-09-01

    The science of color vision testing has evolved since its inception in the late 1700s. Since then, the rudimentary technique of comparing color names has been replaced by more sophisticated methods. Commonly used tests in clinical practice today include isochromatic plates, arrangement tests, anomaloscopes, and lantern tests. Each category has unique attributes that make it suitable for a particular clinical situation. The clinician should be aware of the requirements for administering and grading each test type. Factors such as the quality of the illuminant and the size of the field of view are important elements in setting up a proper color vision laboratory. Currently, no treatment exists for congenital color vision defects. However, studies show that diagnosis of these defects early in life may help children adjust better to tasks at school and may help adults understand their limitations at work. Acquired color vision defects are often used as markers of ocular pathology in the clinical setting. Different color vision tests are appropriate for diagnosing the different categories of defects. Sometimes, a battery of tests may be appropriate. This paper is a review of the current knowledge in the field of color vision testing.

  16. Molecular genetics of colour vision deficiencies.

    PubMed

    Deeb, Samir S

    2004-07-01

    Common variation in colour vision exists among both colour normal and colour deficient subjects. Differences at a few amino acid positions that influence the spectra of the L and M cone pigments account for most of this variation. The genes encoding the L and M photopigments are arranged in head-to-tail arrays on the X-chromosome, beginning with the L and followed by one or more M pigment genes. The L and M pigment genes are highly homologous, which predisposed them to unequal crossing over (recombination) resulting in gene deletions and in formation of L/M hybrid genes that encode a variety of pigments with either L-like or M-like spectra that account for the majority of colour vision defects. Only the first two pigment genes of the L/M array are expressed in the retina and, therefore, need to be considered in predicting colour vision. A common single amino acid polymorphism (serine or alanine) at position 180 of the L-pigment plays an important role both in variation in normal colour vision and in the severity of colour vision defects. Blue cone monochromacy is a rare form of colour vision deficiency that results from mutations that abolish function of both the L and M pigment genes. All the above defects are inherited as X-linked recessive traits. Tritanopia is also a rare autosomal dominant colour vision defect caused by mutations in the S pigment gene located on chromosome 7. Total colour blindness (achromatopsia or rod monochromacy) is a rare autosomal recessive trait caused by mutations in genes encoding the proteins of the photoreceptor cation channel or cone transducin that are essential for function of all classes of cone.

  17. Insect vision as model for machine vision

    NASA Astrophysics Data System (ADS)

    Osorio, D.; Sobey, Peter J.

    1992-11-01

    The neural architecture, neurophysiology and behavioral abilities of insect vision are described, and compared with that of mammals. Insects have a hardwired neural architecture of highly differentiated neurons, quite different from the cerebral cortex, yet their behavioral abilities are in important respects similar to those of mammals. These observations challenge the view that the key to the power of biological neural computation is distributed processing by a plastic, highly interconnected, network of individually undifferentiated and unreliable neurons that has been a dominant picture of biological computation since Pitts and McCulloch's seminal work in the 1940's.

  18. Colour, vision and ergonomics.

    PubMed

    Pinheiro, Cristina; da Silva, Fernando Moreira

    2012-01-01

    This paper is based on a research project - Visual Communication and Inclusive Design-Colour, Legibility and Aged Vision, developed at the Faculty of Architecture of Lisbon. The research has the aim of determining specific design principles to be applied to visual communication design (printed) objects, in order to be easily read and perceived by all. This study target group was composed by a selection of socially active individuals, between 55 and 80 years, and we used cultural events posters as objects of study and observation. The main objective is to overlap the study of areas such as colour, vision, older people's colour vision, ergonomics, chromatic contrasts, typography and legibility. In the end we will produce a manual with guidelines and information to apply scientific knowledge into the communication design projectual practice. Within the normal aging process, visual functions gradually decline; the quality of vision worsens, colour vision and contrast sensitivity are also affected. As people's needs change along with age, design should help people and communities, and improve life quality in the present. Applying principles of visually accessible design and ergonomics, the printed design objects, (or interior spaces, urban environments, products, signage and all kinds of visually information) will be effective, easier on everyone's eyes not only for visually impaired people but also for all of us as we age.

  19. Artificial vision workbench.

    PubMed

    Frenger, P

    1997-01-01

    Machine vision is an important component of medical systems engineering. Inexpensive miniature solid state cameras are now available. This paper describes how these devices can be used as artificial retinas, to take snapshots and moving pictures in monochrome or color. Used in pairs, they produce a stereoscopic field of vision and enable depth perception. Macular and peripheral vision can be simulated electronically. This paper also presents the author's design of an artificial orbit for this synthetic eye. The orbit supports the eye, protects it, and provides attachment points for the ocular motion control system. Convergence and image fusion can be produced, and saccades simulated, along with the other ocular motions. The use of lenses, filters, irises and focusing mechanisms are also discussed. Typical camera-computer interfaces are described, including the use of "frame grabbers" and analog-to-digital image conversion. Software programs for eye positioning, image manipulation, feature extraction and object recognition are discussed, including the application of artificial neural networks.

  20. Periodontium bestows vision!!

    PubMed Central

    Gulati, Minkle; Salaria, Sanjeev Kumar; Anand, Vishal; Jain, Nikil; Pandey, Suraj

    2016-01-01

    The role of periodontium in supporting the tooth structures is well-known. However, less is known about its contribution to the field of ophthalmology. Corneal diseases are among major causes of blindness affecting millions of people worldwide, for which synthetic keratoprosthesis was considered the last resort to restore vision. Yet, these synthetic keratoprosthesis suffered from serious limitations, especially the foreign body reactions invoked by them resulting in extrusion of the whole prosthesis from the eye. To overcome these shortcomings, an autologous osteo-odonto keratoprosthesis utilizing intraoral entities was introduced that could positively restore vision even in cases of severely damaged eyes. The successful functioning of this prosthesis, however, predominantly depended on the presence of a healthy periodontium for grafting. Therefore, the following short communication aims to acknowledge this lesser-known role of the periodontium and other oral structures in bestowing vision to the blind patients. PMID:27563213

  1. Overview of sports vision

    NASA Astrophysics Data System (ADS)

    Moore, Linda A.; Ferreira, Jannie T.

    2003-03-01

    Sports vision encompasses the visual assessment and provision of sports-specific visual performance enhancement and ocular protection for athletes of all ages, genders and levels of participation. In recent years, sports vision has been identified as one of the key performance indicators in sport. It is built on four main cornerstones: corrective eyewear, protective eyewear, visual skills enhancement and performance enhancement. Although clinically well established in the US, it is still a relatively new area of optometric specialisation elsewhere in the world and is gaining increasing popularity with eyecare practitioners and researchers. This research is often multi-disciplinary and involves input from a variety of subject disciplines, mainly those of optometry, medicine, physiology, psychology, physics, chemistry, computer science and engineering. Collaborative research projects are currently underway between staff of the Schools of Physics and Computing (DIT) and the Academy of Sports Vision (RAU).

  2. The photochemical determinants of color vision

    PubMed Central

    Wang, Wenjing; Geiger, James H; Borhan, Babak

    2014-01-01

    The evolution of a variety of important chromophore-dependent biological processes, including microbial light sensing and mammalian color vision, relies on protein modifications that alter the spectral characteristics of a bound chromophore. Three different color opsins share the same chromophore, but have three distinct absorptions that together cover the entire visible spectrum, giving rise to trichromatic vision. The influence of opsins on the absorbance of the chromophore has been studied through methods such as model compounds, opsin mutagenesis, and computational modeling. The recent development of rhodopsin mimic that uses small soluble proteins to recapitulate the binding and wavelength tuning of the native opsins provides a new platform for studying protein-regulated spectral tuning. The ability to achieve far-red shifted absorption in the rhodopsin mimic system was attributed to a combination of the lack of a counteranion proximal to the iminium, and a uniformly neutral electrostatic environment surrounding the chromophore. PMID:24323922

  3. Representing vision and blindness.

    PubMed

    Ray, Patrick L; Cox, Alexander P; Jensen, Mark; Allen, Travis; Duncan, William; Diehl, Alexander D

    2016-01-01

    There have been relatively few attempts to represent vision or blindness ontologically. This is unsurprising as the related phenomena of sight and blindness are difficult to represent ontologically for a variety of reasons. Blindness has escaped ontological capture at least in part because: blindness or the employment of the term 'blindness' seems to vary from context to context, blindness can present in a myriad of types and degrees, and there is no precedent for representing complex phenomena such as blindness. We explore current attempts to represent vision or blindness, and show how these attempts fail at representing subtypes of blindness (viz., color blindness, flash blindness, and inattentional blindness). We examine the results found through a review of current attempts and identify where they have failed. By analyzing our test cases of different types of blindness along with the strengths and weaknesses of previous attempts, we have identified the general features of blindness and vision. We propose an ontological solution to represent vision and blindness, which capitalizes on resources afforded to one who utilizes the Basic Formal Ontology as an upper-level ontology. The solution we propose here involves specifying the trigger conditions of a disposition as well as the processes that realize that disposition. Once these are specified we can characterize vision as a function that is realized by certain (in this case) biological processes under a range of triggering conditions. When the range of conditions under which the processes can be realized are reduced beyond a certain threshold, we are able to say that blindness is present. We characterize vision as a function that is realized as a seeing process and blindness as a reduction in the conditions under which the sight function is realized. This solution is desirable because it leverages current features of a major upper-level ontology, accurately captures the phenomenon of blindness, and can be

  4. Bio-inspired vision

    NASA Astrophysics Data System (ADS)

    Posch, C.

    2012-01-01

    Nature still outperforms the most powerful computers in routine functions involving perception, sensing and actuation like vision, audition, and motion control, and is, most strikingly, orders of magnitude more energy-efficient than its artificial competitors. The reasons for the superior performance of biological systems are subject to diverse investigations, but it is clear that the form of hardware and the style of computation in nervous systems are fundamentally different from what is used in artificial synchronous information processing systems. Very generally speaking, biological neural systems rely on a large number of relatively simple, slow and unreliable processing elements and obtain performance and robustness from a massively parallel principle of operation and a high level of redundancy where the failure of single elements usually does not induce any observable system performance degradation. In the late 1980`s, Carver Mead demonstrated that silicon VLSI technology can be employed in implementing ``neuromorphic'' circuits that mimic neural functions and fabricating building blocks that work like their biological role models. Neuromorphic systems, as the biological systems they model, are adaptive, fault-tolerant and scalable, and process information using energy-efficient, asynchronous, event-driven methods. In this paper, some basics of neuromorphic electronic engineering and its impact on recent developments in optical sensing and artificial vision are presented. It is demonstrated that bio-inspired vision systems have the potential to outperform conventional, frame-based vision acquisition and processing systems in many application fields and to establish new benchmarks in terms of redundancy suppression/data compression, dynamic range, temporal resolution and power efficiency to realize advanced functionality like 3D vision, object tracking, motor control, visual feedback loops, etc. in real-time. It is argued that future artificial vision systems

  5. RiboVision suite for visualization and analysis of ribosomes.

    PubMed

    Bernier, Chad R; Petrov, Anton S; Waterbury, Chris C; Jett, James; Li, Fengbo; Freil, Larry E; Xiong, Xiao; Wang, Lan; Migliozzi, Blacki L R; Hershkovits, Eli; Xue, Yuzhen; Hsiao, Chiaolong; Bowman, Jessica C; Harvey, Stephen C; Grover, Martha A; Wartell, Zachary J; Williams, Loren Dean

    2014-01-01

    RiboVision is a visualization and analysis tool for the simultaneous display of multiple layers of diverse information on primary (1D), secondary (2D), and three-dimensional (3D) structures of ribosomes. The ribosome is a macromolecular complex containing ribosomal RNA and ribosomal proteins and is a key component of life responsible for the synthesis of proteins in all living organisms. RiboVision is intended for rapid retrieval, analysis, filtering, and display of a variety of ribosomal data. Preloaded information includes 1D, 2D, and 3D structures augmented by base-pairing, base-stacking, and other molecular interactions. RiboVision is preloaded with rRNA secondary structures, rRNA domains and helical structures, phylogeny, crystallographic thermal factors, etc. RiboVision contains structures of ribosomal proteins and a database of their molecular interactions with rRNA. RiboVision contains preloaded structures and data for two bacterial ribosomes (Thermus thermophilus and Escherichia coli), one archaeal ribosome (Haloarcula marismortui), and three eukaryotic ribosomes (Saccharomyces cerevisiae, Drosophila melanogaster, and Homo sapiens). RiboVision revealed several major discrepancies between the 2D and 3D structures of the rRNAs of the small and large subunits (SSU and LSU). Revised structures mapped with a variety of data are available in RiboVision as well as in a public gallery (). RiboVision is designed to allow users to distill complex data quickly and to easily generate publication-quality images of data mapped onto secondary structures. Users can readily import and analyze their own data in the context of other work. This package allows users to import and map data from CSV files directly onto 1D, 2D, and 3D levels of structure. RiboVision has features in rough analogy with web-based map services capable of seamlessly switching the type of data displayed and the resolution or magnification of the display. RiboVision is available at .

  6. Developmental disorders of vision.

    PubMed

    Galaburda, Albert M; Duchaine, Bradley C

    2003-08-01

    This review of developmental disorders of vision focuses on only a few of the many disorders that disrupt visual development. Given the enormity of the human visual system in the primate brain and complexity of visual development, however, there are likely hundreds or thousands of types of disorders affecting high-level vision. The rapid progress seen in developmental dyslexia and WMS demonstrates the possibilities and difficulties inherent in researching such disorders, and the authors hope that similar progress will be made for congenital prosopagnosia and other disorders in the near future.

  7. Telescopic vision contact lens

    NASA Astrophysics Data System (ADS)

    Tremblay, Eric J.; Beer, R. Dirk; Arianpour, Ashkan; Ford, Joseph E.

    2011-03-01

    We present the concept, optical design, and first proof of principle experimental results for a telescopic contact lens intended to become a visual aid for age-related macular degeneration (AMD), providing magnification to the user without surgery or external head-mounted optics. Our contact lens optical system can provide a combination of telescopic and non-magnified vision through two independent optical paths through the contact lens. The magnified optical path incorporates a telescopic arrangement of positive and negative annular concentric reflectors to achieve 2.8x - 3x magnification on the eye, while light passing through a central clear aperture provides unmagnified vision.

  8. Night Vision Camera

    NASA Technical Reports Server (NTRS)

    1996-01-01

    PixelVision, Inc. developed the Night Video NV652 Back-illuminated CCD Camera, based on the expertise of a former Jet Propulsion Laboratory employee and a former employee of Scientific Imaging Technologies, Inc. The camera operates without an image intensifier, using back-illuminated and thinned CCD technology to achieve extremely low light level imaging performance. The advantages of PixelVision's system over conventional cameras include greater resolution and better target identification under low light conditions, lower cost and a longer lifetime. It is used commercially for research and aviation.

  9. Is binocular vision worth considering in people with low vision?

    PubMed

    Uzdrowska, Marta; Crossland, Michael; Broniarczyk-Loba, Anna

    2014-01-01

    In someone with good vision, binocular vision provides benefits which could not be obtained by monocular viewing only. People with visual impairment often have abnormal binocularity. However, they often use both eyes simultaneously in their everyday activities. Much remains to be known about binocular vision in people with visual impairment. As the binocular status of people with low vision strongly influences their treatment and rehabilitation, it should be evaluated and considered before diagnosis and further recommendations.

  10. Grounding Our Vision: Brain Research and Strategic Vision

    ERIC Educational Resources Information Center

    Walker, Mike

    2011-01-01

    While recognizing the value of "vision," it could be argued that vision alone--at least in schools--is not enough to rally the financial and emotional support required to translate an idea into reality. A compelling vision needs to reflect substantive, research-based knowledge if it is to spark the kind of strategic thinking and insight…

  11. Grounding Our Vision: Brain Research and Strategic Vision

    ERIC Educational Resources Information Center

    Walker, Mike

    2011-01-01

    While recognizing the value of "vision," it could be argued that vision alone--at least in schools--is not enough to rally the financial and emotional support required to translate an idea into reality. A compelling vision needs to reflect substantive, research-based knowledge if it is to spark the kind of strategic thinking and insight…

  12. How rods respond to single photons: Key adaptations of a G-protein cascade that enable vision at the physical limit of perception.

    PubMed

    Reingruber, Jürgen; Holcman, David; Fain, Gordon L

    2015-11-01

    Rod photoreceptors are among the most sensitive light detectors in nature. They achieve their remarkable sensitivity across a wide variety of species through a number of essential adaptations: a specialized cellular geometry, a G-protein cascade with an unusually stable receptor molecule, a low-noise transduction mechanism, a nearly perfect effector enzyme, and highly evolved mechanisms of feedback control and receptor deactivation. Practically any change in protein expression, enzyme activity, or feedback control can be shown to impair photon detection, either by decreasing sensitivity or signal-to-noise ratio, or by reducing temporal resolution. Comparison of mammals to amphibians suggests that rod outer-segment morphology and the molecules and mechanism of transduction may have evolved together to optimize light sensitivity in darkness, which culminates in the extraordinary ability of these cells to respond to single photons at the ultimate limit of visual perception. © 2015 WILEY Periodicals, Inc.

  13. Object tracking with stereo vision

    NASA Technical Reports Server (NTRS)

    Huber, Eric

    1994-01-01

    A real-time active stereo vision system incorporating gaze control and task directed vision is described. Emphasis is placed on object tracking and object size and shape determination. Techniques include motion-centroid tracking, depth tracking, and contour tracking.

  14. A History of Vision Screening.

    ERIC Educational Resources Information Center

    Appelboom, Tina M.

    1985-01-01

    The vision screening program has a long and interesting history involving educators, pediatricians, optometrists, and ophthamologists. This historical review of vision screening in the schools includes a discussion of amblyopia and screening of preschool students. (Author/CB)

  15. A History of Vision Screening.

    ERIC Educational Resources Information Center

    Appelboom, Tina M.

    1985-01-01

    The vision screening program has a long and interesting history involving educators, pediatricians, optometrists, and ophthamologists. This historical review of vision screening in the schools includes a discussion of amblyopia and screening of preschool students. (Author/CB)

  16. Low Vision Training in Sweden.

    ERIC Educational Resources Information Center

    Inde, Krister

    1978-01-01

    The article describes the team work approach used in Sweden to provide services to the four main categories of visual impairment: central scotoma, nystagmus, loss of peripheral vision while retaining central vision, and amblyopia. (Author/PHR)

  17. Contact Lenses for Vision Correction

    MedlinePlus

    ... Ophthalmologist Patient Stories Español Eye Health / Glasses & Contacts Contact Lenses Sections Contact Lenses for Vision Correction Contact ... to Know About Contact Lenses Colored Contact Lenses Contact Lenses for Vision Correction Leer en Español: Lentes ...

  18. Low Vision Training in Sweden.

    ERIC Educational Resources Information Center

    Inde, Krister

    1978-01-01

    The article describes the team work approach used in Sweden to provide services to the four main categories of visual impairment: central scotoma, nystagmus, loss of peripheral vision while retaining central vision, and amblyopia. (Author/PHR)

  19. A Colour Vision Experiment.

    ERIC Educational Resources Information Center

    Lovett, David; Hore, Kevin

    1991-01-01

    The model for color vision put forward by Edwin Land is explained. The aspects of the theory that can be demonstrated within the classroom are described. A random arrangement of straight-edged colored areas mounted on a screen, called a Mondrian, projectors, and a computer are used to calculate reflectance. (KR)

  20. Dance: Verities, Values, Visions.

    ERIC Educational Resources Information Center

    Boorman, Joyce, Ed.; Harris, Dorothy, Ed.

    The Binational Dance Conference was organized into three focal themes--verities, values, and visions in dance--to emphasize the known and accepted worth and value of dance, and to stimulate through knowledge and idea exchange, imaginative directions for dance in the future of both the United States and Canada. This thematic structure is also the…

  1. What Is Low Vision?

    MedlinePlus

    ... Duffy on 4/10/2017 Understanding Our Shifting Health Insurance Landscape – and What It Means for People with Vision Loss by Maureen Duffy on 3/27/2017 Many Different Hats: An Audio Short Story by Maribel Steel on 3/22/2017 Taking Hold of Happiness When Challenged by a Visual Disability by AFB ...

  2. Two Visions of America

    ERIC Educational Resources Information Center

    Capaldi, Nicholas

    2012-01-01

    Since the seventeenth century, there have been two narratives about modernity in general and America in particular. The author uses the term "narrative" to include (a) facts, (b) arguments, and most important, (c) a larger vision of how one sees the world and chooses to engage the world. The first and originalist narrative is the Lockean Liberty…

  3. Vision for Space Exploration

    NASA Technical Reports Server (NTRS)

    Smith, Bryan K.

    2007-01-01

    Vision tasks include: a) Complete the International Space Station; b) Safely fly the Space Shuttle until 2010; c) Develop and fly the Crew Exploration Vehicle (by 2014); d) Return to the moon (by 2020); e) Sustained and affordable human and robotic program; f) Develop innovative technologies, knowledge, and infrastructures; and g) Promote international and commercial participation.

  4. OH Vision Test

    NASA Image and Video Library

    2014-06-03

    ISS040-E-006738 (3 June 2014) --- In the International Space Station's Harmony node, European Space Agency astronaut Alexander Gerst, Expedition 40 flight engineer, performs an eye exam for the Ocular Health experiment which observes and seeks to understand vision changes during long-term space missions.

  5. A Vision System Model

    DTIC Science & Technology

    1991-06-01

    Finding ................................................................................................. 146 4.6 Internal Transform s...and as basis functions in a recognition/ reconstruction network, as well as methods for integrating color into a vision system. The third major...appears to us internally . They are the color - redness, blueness, greenness - the ap- pearance - fuzzy, crisp - etc. by which we quantify objects we view

  6. Adaptive synthetic vision

    NASA Astrophysics Data System (ADS)

    Julier, Simon J.; Brown, Dennis; Livingston, Mark A.; Thomas, Justin

    2006-05-01

    Through their ability to safely collect video and imagery from remote and potentially dangerous locations, UAVs have already transformed the battlespace. The effectiveness of this information can be greatly enhanced through synthetic vision. Given knowledge of the extrinsic and intrinsic parameters of the camera, synthetic vision superimposes spatially-registered computer graphics over the video feed from the UAV. This technique can be used to show many types of data such as landmarks, air corridors, and the locations of friendly and enemy forces. However, the effectiveness of a synthetic vision system strongly depends on the accuracy of the registration - if the graphics are poorly aligned with the real world they can be confusing, annoying, and even misleading. In this paper, we describe an adaptive approach to synthetic vision that modifies the way in which information is displayed depending upon the registration error. We describe an integrated software architecture that has two main components. The first component automatically calculates registration error based on information about the uncertainty in the camera parameters. The second component uses this information to modify, aggregate, and label annotations to make their interpretation as clear as possible. We demonstrate the use of this approach on some sample datasets.

  7. Two Visions of America

    ERIC Educational Resources Information Center

    Capaldi, Nicholas

    2012-01-01

    Since the seventeenth century, there have been two narratives about modernity in general and America in particular. The author uses the term "narrative" to include (a) facts, (b) arguments, and most important, (c) a larger vision of how one sees the world and chooses to engage the world. The first and originalist narrative is the Lockean Liberty…

  8. Unconventional colour vision.

    PubMed

    Marshall, Justin; Arikawa, Kentaro

    2014-12-15

    Butterflies and stomatopods are certainly outliers in their unconventional colour sense and despite some similarities at first glance, in fact sample the world of colour very differently. In one way, butterflies are relatively conventional, possessing either tri-or tetrachromatic colour vision, then just adding one or several task-specific sub-mechanisms onto this. It is the stomatopods so far that have really pushed the boat out into a different colour vision mechanism. Over 400 million years of independent evolution they have arrived at a solution with more in common with the way a satellite sensor examines the colours of the earth than other animals. Remember, however, that unconventional colour vision is not just the realm of the serially polychromatic. Apparently waterfleas with four classes of spectral receptors living in ponds operate a task-specific spectral sense with no need, or indeed neural processing power, to construct a complex discriminatory mechanism. It seems they have the butterfly added-extra set without the more complex comparative chromatic mechanisms, although in truth, conclusive behavioural proof is lacking. Behavioural observation of colour vision in the ecological context of each animal is vital before making the distinction between conventional and unconventional. Just counting spectral sensitivities is never enough.

  9. VISION AND READING ABILITY.

    ERIC Educational Resources Information Center

    MANGRUM, CHARLES T.

    SIGNIFICANT RESEARCH ON THE PHYSIOLOGICAL AND FUNCTIONAL ASPECTS OF VISION AND READING DISABILITY IS SURVEYED. CONCLUSIONS BASED ON THE LITERATURE IN THE FIELD ARE DISCUSSED. A BIBLIOGRAPHY OF 70 REFERENCES AND A GLOSSARY OF TERMS ARE APPENDED. A TABLE SUMMARIZING REFRACTIVE ERRORS AND EYE DEFECTS CONTRIBUTING TO READING DISABILITY IS INCLUDED.…

  10. Vision: Essential Scaffolding

    ERIC Educational Resources Information Center

    Murphy, Joseph; Torre, Daniela

    2015-01-01

    Few concepts are more noted in the leadership effects research than vision. It is a cardinal element in the school improvement equation as well. Yet, it remains one of the least well-specified components of that algorithm. Based on a comprehensive review of the research on effective leadership and school improvement from 1995 to 2012, we bring…

  11. Low Vision Bicycling.

    ERIC Educational Resources Information Center

    Connor, M.

    1992-01-01

    This article considers bicycling as a means of transportation, not recreation, for individuals with low vision. Considered are evaluation of capabilities, watching for child cyclists, central and peripheral field loss, necessary equipment, potential problems, seasonal and weather considerations, night riding, route planning, basic visual skills…

  12. CONTRIBUTIONS OF VISION SCIENCES.

    ERIC Educational Resources Information Center

    SPACHE, GEORGE D.

    THE IMPLICATIONS OF RESEARCH IN THE VISION SCIENCES FOR READING INSTRUCTION ARE DISCUSSED ON THE BASIS OF (1) STUDIES ON THE PERCEPTUAL BEHAVIOR OF CHILDREN AND THE EFFECT OF LANGUAGE DIRECTIONALITY ON PERCEPTION, (2) STUDIES ON VISUAL CHARACTERISTICS, (3) STUDIES ON THE RELATIONSHIP BETWEEN MOTOR COORDINATION AND READING ABILITY, (4) LONGITUDINAL…

  13. Parallel architectures for vision

    SciTech Connect

    Maresca, M. ); Lavin, M.A. ); Li, H. )

    1988-08-01

    Vision computing involves the execution of a large number of operations on large sets of structured data. Sequential computers cannot achieve the speed required by most of the current applications and therefore parallel architectural solutions have to be explored. In this paper the authors examine the options that drive the design of a vision oriented computer, starting with the analysis of the basic vision computation and communication requirements. They briefly review the classical taxonomy for parallel computers, based on the multiplicity of the instruction and data stream, and apply a recently proposed criterion, the degree of autonomy of each processor, to further classify fine-grain SIMD massively parallel computers. They identify three types of processor autonomy, namely operation autonomy, addressing autonomy, and connection autonomy. For each type they give the basic definitions and show some examples. They focus on the concept of connection autonomy, which they believe is a key point in the development of massively parallel architectures for vision. They show two examples of parallel computers featuring different types of connection autonomy - the Connection Machine and the Polymorphic-Torus - and compare their cost and benefit.

  14. Reduced Vision and Speechreading.

    ERIC Educational Resources Information Center

    Karp, Adrienne

    1988-01-01

    Eye disorders most likely to be experienced by a hearing-impaired person are described, with an explanation of how speechreading performance might be impacted. Recommendations are offered to assist visually impaired speechreaders, through consideration of optimal viewing angles, lighting conditions, use of low vision aids, etc. (JDD)

  15. Giving Machines the Vision

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Amherst Systems manufactures foveal machine vision technology and systems commercially available to end-users and system integrators. This technology was initially developed under NASA contracts NAS9-19335 (Johnson Space Center) and NAS1-20841 (Langley Research Center). This technology is currently being delivered to university research facilities and military sites. More information may be found in www.amherst.com.

  16. Low Vision Bicycling.

    ERIC Educational Resources Information Center

    Connor, M.

    1992-01-01

    This article considers bicycling as a means of transportation, not recreation, for individuals with low vision. Considered are evaluation of capabilities, watching for child cyclists, central and peripheral field loss, necessary equipment, potential problems, seasonal and weather considerations, night riding, route planning, basic visual skills…

  17. Computer Vision Systems

    NASA Astrophysics Data System (ADS)

    Gunasekaran, Sundaram

    Food quality is of paramount consideration for all consumers, and its importance is perhaps only second to food safety. By some definition, food safety is also incorporated into the broad categorization of food quality. Hence, the need for careful and accurate evaluation of food quality is at the forefront of research and development both in the academia and industry. Among the many available methods for food quality evaluation, computer vision has proven to be the most powerful, especially for nondestructively extracting and quantifying many features that have direct relevance to food quality assessment and control. Furthermore, computer vision systems serve to rapidly evaluate the most readily observable foods quality attributes - the external characteristics such as color, shape, size, surface texture etc. In addition, it is now possible, using advanced computer vision technologies, to “see” inside a food product and/or package to examine important quality attributes ordinarily unavailable to human evaluators. With rapid advances in electronic hardware and other associated imaging technologies, the cost-effectiveness and speed of computer vision systems have greatly improved and many practical systems are already in place in the food industry.

  18. Dance: Verities, Values, Visions.

    ERIC Educational Resources Information Center

    Boorman, Joyce, Ed.; Harris, Dorothy, Ed.

    The Binational Dance Conference was organized into three focal themes--verities, values, and visions in dance--to emphasize the known and accepted worth and value of dance, and to stimulate through knowledge and idea exchange, imaginative directions for dance in the future of both the United States and Canada. This thematic structure is also the…

  19. Synthetic Vision Workshop 2

    NASA Technical Reports Server (NTRS)

    Kramer, Lynda J. (Compiler)

    1999-01-01

    The second NASA sponsored Workshop on Synthetic/Enhanced Vision (S/EV) Display Systems was conducted January 27-29, 1998 at the NASA Langley Research Center. The purpose of this workshop was to provide a forum for interested parties to discuss topics in the Synthetic Vision (SV) element of the NASA Aviation Safety Program and to encourage those interested parties to participate in the development, prototyping, and implementation of S/EV systems that enhance aviation safety. The SV element addresses the potential safety benefits of synthetic/enhanced vision display systems for low-end general aviation aircraft, high-end general aviation aircraft (business jets), and commercial transports. Attendance at this workshop consisted of about 112 persons including representatives from industry, the FAA, and other government organizations (NOAA, NIMA, etc.). The workshop provided opportunities for interested individuals to give presentations on the state of the art in potentially applicable systems, as well as to discuss areas of research that might be considered for inclusion within the Synthetic Vision Element program to contribute to the reduction of the fatal aircraft accident rate. Panel discussions on topical areas such as databases, displays, certification issues, and sensors were conducted, with time allowed for audience participation.

  20. Vision: Essential Scaffolding

    ERIC Educational Resources Information Center

    Murphy, Joseph; Torre, Daniela

    2015-01-01

    Few concepts are more noted in the leadership effects research than vision. It is a cardinal element in the school improvement equation as well. Yet, it remains one of the least well-specified components of that algorithm. Based on a comprehensive review of the research on effective leadership and school improvement from 1995 to 2012, we bring…

  1. Visions of Mobile Learning

    ERIC Educational Resources Information Center

    T.H.E. Journal, 2011

    2011-01-01

    It is almost a foregone conclusion that the mobile device will become an indispensable tool for learning in the future. That's why "T.H.E. Journal" asked a number of educators to let their imaginations go wild and conjure up visions of the future of the device in the classroom. This paper presents the views of educators who conjure up the mobile…

  2. Chapter 3: Develop a Vision

    PubMed Central

    Jones, Loretta; Meade, Barbara; Norris, Keith; Lucas-Wright, Aziza; Jones, Felica; Moini, Moraya; Jones, Andrea; Koegel, Paul

    2016-01-01

    The Vision stage is the development of the agreed-upon framework for the study, including identifying the issue, the community, the stakeholders, and major aspects of the approach. Achieving the Vision requires planning through a Framing Committee, agreeing on a vision by sharing perspectives and identifying commonalities or “win-wins” that hold the partnership together for community benefit, and evaluating the emergence of the Vision and the partnership. Here, we review tools and strategies. PMID:20088078

  3. Molecular Convergence of Infrared Vision in Snakes

    PubMed Central

    Yokoyama, Shozo; Altun, Ahmet; DeNardo, Dale F.

    2011-01-01

    It has been discovered that the transient receptor potential ankyrin 1 (TRPA1) proteins of Boidae (boas), Pythonidae (pythons), and Crotalinae (pit vipers) are used to detect infrared radiation, but the molecular mechanism for detecting the infrared radiation is unknown. Here, relating the amino acid substitutions in their TRPA1 proteins and the functional differentiations, we propose that three parallel amino acid changes (L330M, Q391H, and S434T) are responsible for the development of infrared vision in the three groups of snakes. Protein modeling shows that the three amino acid changes alter the structures of the central region of their ankyrin repeats. PMID:20937734

  4. Vision in water.

    PubMed

    Atchison, David A; Valentine, Emma L; Gibson, Georgina; Thomas, Hannah R; Oh, Sera; Pyo, Young Ah; Lacherez, Philippe; Mathur, Ankit

    2013-09-06

    The purpose of this study is to determine visual performance in water, including the influence of pupil size. The water environment was simulated by placing goggles filled with saline in front of the eyes with apertures placed at the front of the goggles. Correction factors were determined for the different magnification under this condition in order to estimate vision in water. Experiments were conducted on letter visual acuity (seven participants), grating resolution (eight participants), and grating contrast sensitivity (one participant). For letter acuity, mean loss of vision in water, compared to corrected vision in air, varied between 1.1 log min of arc resolution (logMAR) for a 1 mm aperture to 2.2 logMAR for a 7 mm aperture. The vision in min of arc was described well by a linear relationship with pupil size. For grating acuity, mean loss varied between 1.1 logMAR for a 2 mm aperture to 1.2 logMAR for a 6 mm aperture. Contrast sensitivity for a 2 mm aperture deteriorated as spatial frequency increased with a 2 log unit loss by 3 c/°. Superimposed on this deterioration were depressions (notches) in sensitivity with the first three notches occurring at 0.45, 0.8, and 1.3 c/° with estimates for water of 0.39, 0.70, and 1.13 c/°. In conclusion, vision in water is poor. It becomes worse as pupil size increases, but the effects are much more marked for letter targets than for grating targets.

  5. Registration of Vision 45 Wheat

    USDA-ARS?s Scientific Manuscript database

    Vision 45’ (Reg. No. CV-1110, PI 667642), is a hard red winter (HRW) wheat (Triticum aestivum L.) cultivar that was developed and tested as VA07HRW-45 and released by the Virginia Agricultural Experiment Station in 2012. Vision 45 was derived from the cross ‘Provinciale’/‘Vision 10’ using a modifie...

  6. Superintendent Leadership and Districtwide Vision.

    ERIC Educational Resources Information Center

    Lilly, Edward R.

    The concept of superintendent "vision" as a key element of effective leadership is discussed in this paper, which develops a framework for understanding the creation of vision, its implementation and articulation, and organizational impact. Vision differs from strategy in that it represents a set of beliefs about the school district's aspiring…

  7. Is School Vision Screening Effective?

    ERIC Educational Resources Information Center

    Yawn, Barbara P.; And Others

    1996-01-01

    This study followed children retrospectively from kindergarten through 12th grade to examine incidence of abnormal school vision screening tests and rates of follow-up by specialists. School vision screening provided first indication of abnormal visual acuity in 76% of the children. Results support the notion that school vision screening is…

  8. Vision Screening For Head Starters.

    ERIC Educational Resources Information Center

    Foley, Celia

    To determine which children in the Head Start program may have vision problems, Head Start teachers and staff do vision "screening." This booklet demonstrates how to do the screening using the Snellen "E Chart." Trouble signs that the test administrator should be aware of are listed, and vision scores are explained simply.…

  9. Vision care: a compensation cornerstone.

    PubMed

    Steere, R W

    2001-03-01

    Vision care is a benefit that provides advantages for both employers and employees, and it has become an essential element of most competitive benefit packages. Well-designed vision care programs offer participants choice, options, self-help and value. An option that employers may want to consider is reduced prices on laser vision correction procedures.

  10. Is School Vision Screening Effective?

    ERIC Educational Resources Information Center

    Yawn, Barbara P.; And Others

    1996-01-01

    This study followed children retrospectively from kindergarten through 12th grade to examine incidence of abnormal school vision screening tests and rates of follow-up by specialists. School vision screening provided first indication of abnormal visual acuity in 76% of the children. Results support the notion that school vision screening is…

  11. Vision Care and the Nation's Children.

    ERIC Educational Resources Information Center

    American Optometric Association, St. Louis, MO.

    Aspects of vision and vision care considered are the following: extent and types of vision defects of American children; importance of vision care in pre-school years, elementary, and secondary school and beyond; and manpower resources in vision care today, the extent of vision testing and care, special problem areas, and governmental support.…

  12. Visions of Delight, Visions of Doubt: The Relationship Between Emotion and Cognition in Teachers' Vision.

    ERIC Educational Resources Information Center

    Hammerness, Karen

    This paper examines the concept of teacher vision, showing how vision serves as a means for teachers to guide and measure their work. It discusses how teachers' passionate commitments do not divert them from their work but rather direct and shape their thinking and planning and their learning about their work. The paper also shows how vision, in…

  13. Evolution of vertebrate colour vision.

    PubMed

    Jacobs, Gerald H; Rowe, Mickey P

    2004-07-01

    Recent years have witnessed a growing interest in learning how colour vision has evolved. This trend has been fuelled by an enhanced understanding of the nature and extent of colour vision among contemporary species, by a deeper understanding of the paleontological record and by the application of new tools from molecular biology. This review provides an assessment of the progress in understanding the evolution of vertebrate colour vision. In so doing, we offer accounts of the evolution of three classes of mechanism important for colour vision--photopigment opsins, oil droplets and retinal organisation--and then examine details of how colour vision has evolved among mammals and, more specifically, among primates.

  14. Conscious Vision in Action.

    PubMed

    Briscoe, Robert; Schwenkler, John

    2015-09-01

    It is natural to assume that the fine-grained and highly accurate spatial information present in visual experience is often used to guide our bodily actions. Yet this assumption has been challenged by proponents of the Two Visual Systems Hypothesis (TVSH), according to which visuomotor programming is the responsibility of a "zombie" processing stream whose sources of bottom-up spatial information are entirely non-conscious (Clark, 2007, 2009; Goodale & Milner, 1992, 2004a; Milner & Goodale, 1995/2006, 2008). In many formulations of TVSH, the role of conscious vision in action is limited to "recognizing objects, selecting targets for action, and determining what kinds of action, broadly speaking, to perform" (Clark, 2007, p. 570). Our aim in this study is to show that the available evidence not only fails to support this dichotomous view but actually reveals a significant role for conscious vision in motor programming, especially for actions that require deliberate attention.

  15. Advanced night vision goggles

    NASA Astrophysics Data System (ADS)

    Thacker, Clinton

    2003-02-01

    The Advanced Night Vision Goggle (ANVG) program is developing integrated wide field of view (WFOV) helmet-mounted image intensifier night vision goggle systems. ANVG will provide a FOV of approximately 40° (vertical) × 100° (horizontal) and an integrated heads-up display for overlay of flight symbology and/or FLIR imagery. The added FLIR complements the I2 imagery in out of the window or ground applications. ANVG will significantly improve safety, situational awareness, and mission capabilities in differing environments. ANVG achieves the ultra wide FOV using four image intensifier tubes in a head-mounted configuration. Additional features include a miniature flat panel display and a lightweight uncooled FLIR. The integrated design will demonstrate the capability of helmet-mounted I2 and FLIR image fusion. Fusion will be accomplished optically and will offer significant opportunities for ground applications. This paper summarizes the basic technologies, lessons learned, and program status.

  16. 2015 Enterprise Strategic Vision

    SciTech Connect

    2015-08-01

    This document aligns with the Department of Energy Strategic Plan for 2014-2018 and provides a framework for integrating our missions and direction for pursuing DOE’s strategic goals. The vision is a guide to advancing world-class science and engineering, supporting our people, modernizing our infrastructure, and developing a management culture that operates a safe and secure enterprise in an efficient manner.

  17. Bird Vision System

    NASA Technical Reports Server (NTRS)

    2008-01-01

    The Bird Vision system is a multicamera photogrammerty software application that runs on a Microsoft Windows XP platform and was developed at Kennedy Space Center by ASRC Aerospace. This software system collects data about the locations of birds within a volume centered on the Space Shuttle and transmits it in real time to the laptop computer of a test director in the Launch Control Center (LCC) Firing Room.

  18. Vision, Instruction and Action

    DTIC Science & Technology

    1990-04-01

    MONITORING AGENCY NAME & ADORESS(l differnin from Co’rollina Office ) It. SECURITY CLASS (f this Fepot) Office of Naval Research UNCLASSIFIED Information...rees olds, if notooer, aid Identify by Moath nmber) This thesis describes Sonja, a system which uses instructions in the course of visually- guided ...Sonja, a system which uses instructions in the course of visually- guided activity. The thesis explores an integration of research in vision, activity

  19. Robotic Vision for Welding

    NASA Technical Reports Server (NTRS)

    Richardson, R. W.

    1986-01-01

    Vision system for robotic welder looks at weld along axis of welding electrode. Gives robot view of most of weld area, including yet-unwelded joint, weld pool, and completed weld bead. Protected within welding-torch body, lens and fiber bundle give robot closeup view of weld in progress. Relayed to video camera on robot manipulator frame, weld image provides data for automatic control of robot motion and welding parameters.

  20. Vision without the Image

    PubMed Central

    Chen, Bo; Perona, Pietro

    2016-01-01

    Novel image sensors transduce the stream of photons directly into asynchronous electrical pulses, rather than forming an image. Classical approaches to vision start from a good quality image and therefore it is tempting to consider image reconstruction as a first step to image analysis. We propose that, instead, one should focus on the task at hand (e.g., detection, tracking or control) and design algorithms that compute the relevant variables (class, position, velocity) directly from the stream of photons. We discuss three examples of such computer vision algorithms and test them on simulated data from photon-counting sensors. Such algorithms work just-in-time, i.e., they complete classification, search and tracking with high accuracy as soon as the information is sufficient, which is typically before there are enough photons to form a high-quality image. We argue that this is particularly useful when the photons are few or expensive, e.g., in astronomy, biological imaging, surveillance and night vision. PMID:27058543

  1. Rejuvenating rice proteomics: facts, challenges, and visions.

    PubMed

    Agrawal, Ganesh Kumar; Jwa, Nam-Soo; Iwahashi, Yumiko; Yonekura, Masami; Iwahashi, Hitoshi; Rakwal, Randeep

    2006-10-01

    Proteomics is progressing at an unprecedented pace, as can be exemplified by the progress in model organisms such as yeast, bacteria, and mammals. Proteomics research in plants, however, has not progressed at the same pace. Unscrambling of the genome sequences of the dicotyledoneous Arabidopsis thaliana (L.) and monocotyledoneous rice (Oryza sativa L.) plant species, respectively, has made them accessible reference organisms to study plant proteomics. Study of these two reference plants is expected to unravel the mystery of plant biology. Rice, a critically important food crop on the earth, has been termed a "cornerstone" and the "Rosetta stone" for functional genomics of cereal crops. Here, we look at the progress in unraveling rice proteomes and present the facts, challenges, and vision. The text is divided into two major parts: the first part presents the facts and the second part discusses the challenges and vision. The facts include the technology and its use in developing proteomes, which have been critically and constructively reviewed. The challenges and vision deal with the establishment of technologies to exhaustively investigate the protein components of a proteome, to generate high-resolution gel-based reference maps, and to give rice proteomics a functional dimension by studying PTMs and isolation of multiprotein complexes. Finally, we direct a vision on rice proteomics. This is our third review in series on rice proteomics, which aims to stimulate an objective discussion among rice researchers and to understand the necessity and impact of unraveling rice proteomes to their full potential.

  2. Machine vision - Automated visual inspection and robot vision

    SciTech Connect

    Vernon, D. )

    1991-01-01

    The subject of machine vision is treated with emphasis on fundamental tools for image acquisition, processing, and analysis. Topics discussed include an introduction to computer vision, illumination and sensors, image acquisition and representation, fundamentals of digital image processing, the segmentation problem, and image analysis. The book also covers techniques for shape description, robot programming and robot vision, and an introduction to image understanding. 250 refs.

  3. Wearable Improved Vision System for Color Vision Deficiency Correction

    PubMed Central

    Riccio, Daniel; Di Perna, Luigi; Sanniti Di Baja, Gabriella; De Nino, Maurizio; Rossi, Settimio; Testa, Francesco; Simonelli, Francesca; Frucci, Maria

    2017-01-01

    Color vision deficiency (CVD) is an extremely frequent vision impairment that compromises the ability to recognize colors. In order to improve color vision in a subject with CVD, we designed and developed a wearable improved vision system based on an augmented reality device. The system was validated in a clinical pilot study on 24 subjects with CVD (18 males and 6 females, aged 37.4 ± 14.2 years). The primary outcome was the improvement in the Ishihara Vision Test score with the correction proposed by our system. The Ishihara test score significantly improved (\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$p = 0.03$ \\end{document}) from 5.8 ± 3.0 without correction to 14.8 ± 5.0 with correction. Almost all patients showed an improvement in color vision, as shown by the increased test scores. Moreover, with our system, 12 subjects (50%) passed the vision color test as normal vision subjects. The development and preliminary validation of the proposed platform confirm that a wearable augmented-reality device could be an effective aid to improve color vision in subjects with CVD. PMID:28507827

  4. Wearable Improved Vision System for Color Vision Deficiency Correction.

    PubMed

    Melillo, Paolo; Riccio, Daniel; Di Perna, Luigi; Sanniti Di Baja, Gabriella; De Nino, Maurizio; Rossi, Settimio; Testa, Francesco; Simonelli, Francesca; Frucci, Maria

    2017-01-01

    Color vision deficiency (CVD) is an extremely frequent vision impairment that compromises the ability to recognize colors. In order to improve color vision in a subject with CVD, we designed and developed a wearable improved vision system based on an augmented reality device. The system was validated in a clinical pilot study on 24 subjects with CVD (18 males and 6 females, aged 37.4 ± 14.2 years). The primary outcome was the improvement in the Ishihara Vision Test score with the correction proposed by our system. The Ishihara test score significantly improved ([Formula: see text]) from 5.8 ± 3.0 without correction to 14.8 ± 5.0 with correction. Almost all patients showed an improvement in color vision, as shown by the increased test scores. Moreover, with our system, 12 subjects (50%) passed the vision color test as normal vision subjects. The development and preliminary validation of the proposed platform confirm that a wearable augmented-reality device could be an effective aid to improve color vision in subjects with CVD.

  5. [Vision and car driving ability].

    PubMed

    Wilhelm, Helmut

    2011-05-01

    Visual functions relevant for car driving are: Visual acuity, contrast and twilight vision, visual field, ocular motility and alignment and colour vision. Generally accepted and standardized tests are available for visual acuity and visual field. Maximum permissible values have been defined arbitrarily and are hardly supported by studies. European standards have been published comprising also contrast and twilight vision. When examining driving ability progressive and treatable ocular disorders such as cataract and glaucoma have to be considered.

  6. National Hydrogen Vision Meeting Proceedings

    SciTech Connect

    2001-11-01

    This document provides presentations and summaries of the notes from the National Hydrogen Vision Meeting''s facilitated breakout sessions. The Vision Meeting, which took place November 15-16, 2001, kicked off the public-private partnership that will pave the way to a more secure and cleaner energy future for America. These proceedings were compiled into a formal report, A National Vision of America''s Transition to a Hydrogen Economy - To 2030 and Beyond, which is also available online.

  7. Peripheral vision displays: The future

    NASA Technical Reports Server (NTRS)

    Assenhein, H. M.

    1984-01-01

    Several areas of research relating to peripheral vision displays used by aircraft pilots are outlined: fiber optics, display color, and holography. Various capacities and specifications of gas and solid state lasers are enumerated. These lasers are potential sources of green light for the peripheral vision displays. The relative radiance required for rod and cone vision at different wavelengths is presented graphically. Calculated and measured retinal sensitivities (foveal and peripheral) are given for wavelength produced by various lasers.

  8. Intelligent robots and computer vision

    SciTech Connect

    Casasent, D.P.

    1986-01-01

    This book presents the papers given at a conference on artificial intelligence and robot vision. Topics considered at the conference included pattern recognition, image processing for intelligent robotics, three-dimensional vision (depth and motion), vision modeling and shape estimation, spatial reasoning, the symbolic processing visual information, robotic sensors and applications, intelligent control architectures for robot systems, robot languages and programming, human-machine interfaces, robotics applications, and architectures of robotics.

  9. The development of vision.

    PubMed

    Mercuri, Eugenio; Baranello, Giovanni; Romeo, Domenico M M; Cesarini, Laura; Ricci, Daniela

    2007-12-01

    Disorders of visual function are common findings in children with neonatal brain lesions of antenatal and perinatal onset. In the last few years the development of age appropriate batteries for assessing visual function in the first years and the combined use of neuroimaging and neurophysiological techniques have allowed to achieve better understanding of the mechanisms underlying development of vision in low risk infants and in those with brain lesions. We will review the main models of visual development and the tests available to assess visual function in infancy, focusing on the recently described battery of tests for assessing early visual abilities in preterm and full term infants.

  10. Vision Guided Laryngoscopic Analysis

    NASA Astrophysics Data System (ADS)

    Yung, H. C.; Allen, C. R.; Beresford, R.; Welch, A.

    1988-10-01

    This paper describes a vision guided endoscopic computer system applied in the analysis of static vocal fold images of patients. The system comprises a flexible nasal-endoscope and a PC compatible compatible computer supported by a fully interactive menu-driven software environment which performs the analysis tasks. It is the intention of this paper to present the philosophy of the approach, the construction of the prototype, the results of the investigation and the merits and drawbacks of the prototype at this stage of development. The cost effectiveness of such system being used in private clinics and general hospitals as an expert adviser to the examining doctor will also be discussed.

  11. Vision in flying insects.

    PubMed

    Egelhaaf, Martin; Kern, Roland

    2002-12-01

    Vision guides flight behaviour in numerous insects. Despite their small brain, insects easily outperform current man-made autonomous vehicles in many respects. Examples are the virtuosic chasing manoeuvres male flies perform as part of their mating behaviour and the ability of bees to assess, on the basis of visual motion cues, the distance travelled in a novel environment. Analyses at both the behavioural and neuronal levels are beginning to unveil reasons for such extraordinary capabilities of insects. One recipe for their success is the adaptation of visual information processing to the specific requirements of the behavioural tasks and to the specific spatiotemporal properties of the natural input.

  12. Conscious vision for action versus unconscious vision for action?

    PubMed

    Brogaard, Berit

    2011-08-01

    David Milner and Melvyn Goodale's dissociation hypothesis is commonly taken to state that there are two functionally specialized cortical streams of visual processing originating in striate (V1) cortex: a dorsal, action-related "unconscious" stream and a ventral, perception-related "conscious" stream. As Milner and Goodale acknowledge, findings from blindsight studies suggest a more sophisticated picture that replaces the distinction between unconscious vision for action and conscious vision for perception with a tripartite division between unconscious vision for action, conscious vision for perception, and unconscious vision for perception. The combination excluded by the tripartite division is the possibility of conscious vision for action. But are there good grounds for concluding that there is no conscious vision for action? There is now overwhelming evidence that illusions and perceived size can have a significant effect on action (Bruno & Franz, 2009; Dassonville & Bala, 2004; Franz & Gegenfurtner, 2008; McIntosh & Lashley, 2008). There is also suggestive evidence that any sophisticated visual behavior requires collaboration between the two visual streams at every stage of the process (Schenk & McIntosh, 2010). I nonetheless want to make a case for the tripartite division between unconscious vision for action, conscious vision for perception, and unconscious vision for perception. My aim here is not to refute the evidence showing that conscious vision can affect action but rather to argue (a) that we cannot gain cognitive access to action-guiding dorsal stream representations, and (b) that these representations do not correlate with phenomenal consciousness. This vindicates the semi-conservative view that the dissociation hypothesis is best understood as a tripartite division. Copyright © 2011 Cognitive Science Society, Inc.

  13. Birth and evolution of visionics

    NASA Astrophysics Data System (ADS)

    Wiseman, Robert S.

    1992-09-01

    The success of the U.S. Army's Night Vision Program at Fort Belvoir, VA was significantly influenced by the evolution and timely culmination of Visionics technology which was initiated by Mr. John Johnson. In the late 1950's, Visionics technology started with concern for Near Infrared (NIR) and Image Intensifier (II) Night Vision developments. It resulted in the Johnson Criteria which coupled system physical characteristics to visual performance by using resolution of line pairs across the minimum dimension of a target. This led to development of image evaluation procedures and standardized laboratory testing. Later the Visionics team addressed the Far Infrared (FIR) system performance and developed a series of FLIR Performance Models. The Visionic's Static Performance Model computer code was accepted and proliferated widely by the mid-70's. Visionics moved from static viewing to address the problems of search effectiveness. Then came more work on target signatures and the consideration of the effects of fog, rain, snow, artillery barrages, and realistic battlefield conditions on system performance in order to assure the utility of fielded equipments for all theaters of interest. The general use of the various Visionics models and methodology throughout Government and Industry is recognition of the contributions made by Mr. John Johnson and his Visionics staff.

  14. The measurement of vision disability.

    PubMed

    Massof, Robert W

    2002-08-01

    The American Medical Association's (AMA) visual efficiency scale, a vision disability metric based on visual impairment measurements, was adopted in 1925. That scale was based on a 30-year history of theoretical models in vision economics, a misinterpretation of Snellen notation for visual acuity, and an erroneous application of Weber's psychophysical law. The AMA visual efficiency scale survived uncontested for 75 years. In 2001, the AMA adopted a new vision disability scale based on logarithmic transformations of visual acuity and visual field diameter. Like the earlier visual efficiency scale, the new scale is theoretical-it is not supported by any data that speak to the relationship between vision disability and visual impairments. Attempts to measure vision disability date to the early 1980s with the development of self-assessment visual function rating scale questionnaires. Nearly all of the questionnaires developed over the last 20 years use Likert scales, but use them incorrectly. The development of a vision disability metric based on Likert scaling parallels the historical development of other forms of measurement. A tutorial review of psychometrics-classical test theory, item response theory, and Rasch analysis-shows how vision disability measurement scales can be estimated from Likert-type visual function rating scales. We conclude that preliminary data relating measures of vision disability to measures of visual acuity and visual fields support the new AMA vision disability scale.

  15. Benchmarking neuromorphic vision: lessons learnt from computer vision

    PubMed Central

    Tan, Cheston; Lallee, Stephane; Orchard, Garrick

    2015-01-01

    Neuromorphic Vision sensors have improved greatly since the first silicon retina was presented almost three decades ago. They have recently matured to the point where they are commercially available and can be operated by laymen. However, despite improved availability of sensors, there remains a lack of good datasets, while algorithms for processing spike-based visual data are still in their infancy. On the other hand, frame-based computer vision algorithms are far more mature, thanks in part to widely accepted datasets which allow direct comparison between algorithms and encourage competition. We are presented with a unique opportunity to shape the development of Neuromorphic Vision benchmarks and challenges by leveraging what has been learnt from the use of datasets in frame-based computer vision. Taking advantage of this opportunity, in this paper we review the role that benchmarks and challenges have played in the advancement of frame-based computer vision, and suggest guidelines for the creation of Neuromorphic Vision benchmarks and challenges. We also discuss the unique challenges faced when benchmarking Neuromorphic Vision algorithms, particularly when attempting to provide direct comparison with frame-based computer vision. PMID:26528120

  16. Python and computer vision

    SciTech Connect

    Doak, J. E.; Prasad, Lakshman

    2002-01-01

    This paper discusses the use of Python in a computer vision (CV) project. We begin by providing background information on the specific approach to CV employed by the project. This includes a brief discussion of Constrained Delaunay Triangulation (CDT), the Chordal Axis Transform (CAT), shape feature extraction and syntactic characterization, and normalization of strings representing objects. (The terms 'object' and 'blob' are used interchangeably, both referring to an entity extracted from an image.) The rest of the paper focuses on the use of Python in three critical areas: (1) interactions with a MySQL database, (2) rapid prototyping of algorithms, and (3) gluing together all components of the project including existing C and C++ modules. For (l), we provide a schema definition and discuss how the various tables interact to represent objects in the database as tree structures. (2) focuses on an algorithm to create a hierarchical representation of an object, given its string representation, and an algorithm to match unknown objects against objects in a database. And finally, (3) discusses the use of Boost Python to interact with the pre-existing C and C++ code that creates the CDTs and CATS, performs shape feature extraction and syntactic characterization, and normalizes object strings. The paper concludes with a vision of the future use of Python for the CV project.

  17. 2020 Vision Project Summary

    SciTech Connect

    Gordon, K.W.; Scott, K.P.

    2000-11-01

    Since the 2020 Vision project began in 1996, students from participating schools have completed and submitted a variety of scenarios describing potential world and regional conditions in the year 2020 and their possible effect on US national security. This report summarizes the students' views and describes trends observed over the course of the 2020 Vision project's five years. It also highlights the main organizational features of the project. An analysis of thematic trends among the scenarios showed interesting shifts in students' thinking, particularly in their views of computer technology, US relations with China, and globalization. In 1996, most students perceived computer technology as highly beneficial to society, but as the year 2000 approached, this technology was viewed with fear and suspicion, even personified as a malicious, uncontrollable being. Yet, after New Year's passed with little disruption, students generally again perceived computer technology as beneficial. Also in 1996, students tended to see US relations with China as potentially positive, with economic interaction proving favorable to both countries. By 2000, this view had transformed into a perception of China emerging as the US' main rival and ''enemy'' in the global geopolitical realm. Regarding globalization, students in the first two years of the project tended to perceive world events as dependent on US action. However, by the end of the project, they saw the US as having little control over world events and therefore, we Americans would need to cooperate and compromise with other nations in order to maintain our own well-being.

  18. Coherent laser vision system

    SciTech Connect

    Sebastion, R.L.

    1995-10-01

    The Coherent Laser Vision System (CLVS) is being developed to provide precision real-time 3D world views to support site characterization and robotic operations and during facilities Decontamination and Decommissioning. Autonomous or semiautonomous robotic operations requires an accurate, up-to-date 3D world view. Existing technologies for real-time 3D imaging, such as AM laser radar, have limited accuracy at significant ranges and have variability in range estimates caused by lighting or surface shading. Recent advances in fiber optic component technology and digital processing components have enabled the development of a new 3D vision system based upon a fiber optic FMCW coherent laser radar. The approach includes a compact scanner with no-moving parts capable of randomly addressing all pixels. The system maintains the immunity to lighting and surface shading conditions which is characteristic to coherent laser radar. The random pixel addressability allows concentration of scanning and processing on the active areas of a scene, as is done by the human eye-brain system.

  19. Colour vision in billfish.

    PubMed Central

    Fritsches, K A; Partridge, J C; Pettigrew, J D; Marshall, N J

    2000-01-01

    Members of the billfish family are highly visual predatory teleosts inhabiting the open ocean. Little is known about their visual abilities in detail, but past studies have indicated that these fishes were likely to be monochromats. This study, however, presents evidence of two anatomically distinct cone types in billfish. The cells are arranged in a regular mosaic pattern of single and twin cones as in many fishes, and this arrangement suggests that the different cone types also show different spectral sensitivity, which is the basis for colour vision. First measurements using microspectrophotometry (MSP) revealed a peak absorption of the rod pigment at 484 nm, indicating that MSP, despite technical difficulties, will be a decisive tool in proving colour vision in these offshore fishes. When hunting, billfish such as the sailfish flash bright blue bars on their sides. This colour reflects largely in ultraviolet (UV) light at 350 nm as revealed by spectrophotometric measurements. Billfish lenses block light of wavelengths below 400 nm, presumably rendering the animal blind to the UV component of its own body colour. Interestingly, at least two prey species of billfish have lenses transmitting light in the UV waveband and are therefore likely to perceive a large fraction of the UV peak found in the blue bar of the sailfish. The possible biological significance of this finding is discussed. PMID:11079409

  20. Colour vision in billfish.

    PubMed

    Fritsches, K A; Partridge, J C; Pettigrew, J D; Marshall, N J

    2000-09-29

    Members of the billfish family are highly visual predatory teleosts inhabiting the open ocean. Little is known about their visual abilities in detail, but past studies have indicated that these fishes were likely to be monochromats. This study, however, presents evidence of two anatomically distinct cone types in billfish. The cells are arranged in a regular mosaic pattern of single and twin cones as in many fishes, and this arrangement suggests that the different cone types also show different spectral sensitivity, which is the basis for colour vision. First measurements using microspectrophotometry (MSP) revealed a peak absorption of the rod pigment at 484 nm, indicating that MSP, despite technical difficulties, will be a decisive tool in proving colour vision in these offshore fishes. When hunting, billfish such as the sailfish flash bright blue bars on their sides. This colour reflects largely in ultraviolet (UV) light at 350 nm as revealed by spectrophotometric measurements. Billfish lenses block light of wavelengths below 400 nm, presumably rendering the animal blind to the UV component of its own body colour. Interestingly, at least two prey species of billfish have lenses transmitting light in the UV waveband and are therefore likely to perceive a large fraction of the UV peak found in the blue bar of the sailfish. The possible biological significance of this finding is discussed.

  1. Preschool vision screening.

    PubMed Central

    Jarvis, S N; Tamhne, R C; Thompson, L; Francis, P M; Anderson, J; Colver, A F

    1991-01-01

    Although a good case for preschool screening for vision defects can be made there is very little evidence that existing programmes are effective in practice. A comparative trial of three different methods of preschool vision screening is described. Some 7000 children initially aged 5 months (younger cohorts) and 30 months (older cohorts) in three matched areas entered the trial during 1987. During 18 months of follow up new visual and ocular defects among these children were ascertained through ophthalmology outpatients and from optician records. Screening at 35 months by an orthoptist based in the community is superior to conventional health visitor surveillance at 30 months and to an agreed programme of primary care screening for squint at 30-36 months as judged by screening sensitivity (100% v 50% v 50%) and the incidence of treated target conditions (17 v 3 v 5 per 1000 person years). A notable feature in the area served by the orthoptist is that 13 children received treatment for straight eyed visual acuity loss from among 1000 children whereas there were no such cases among 2500 in the comparison areas. In the younger cohorts (that is, screening at age 5-9 months) all three programmes showed equally poor results, only one of the eight treated target conditions arising from all 3500 younger children being screen detected. PMID:2025002

  2. Industrial robot's vision systems

    NASA Astrophysics Data System (ADS)

    Iureva, Radda A.; Raskin, Evgeni O.; Komarov, Igor I.; Maltseva, Nadezhda K.; Fedosovsky, Michael E.

    2016-03-01

    Due to the improved economic situation in the high technology sectors, work on the creation of industrial robots and special mobile robotic systems are resumed. Despite this, the robotic control systems mostly remained unchanged. Hence one can see all advantages and disadvantages of these systems. This is due to lack of funds, which could greatly facilitate the work of the operator, and in some cases, completely replace it. The paper is concerned with the complex machine vision of robotic system for monitoring of underground pipelines, which collects and analyzes up to 90% of the necessary information. Vision Systems are used to identify obstacles to the process of movement on a trajectory to determine their origin, dimensions and character. The object is illuminated in a structured light, TV camera records projected structure. Distortions of the structure uniquely determine the shape of the object in view of the camera. The reference illumination is synchronized with the camera. The main parameters of the system are the basic distance between the generator and the lights and the camera parallax angle (the angle between the optical axes of the projection unit and camera).

  3. Phantom vision: a graphic description.

    PubMed

    Maloof, Anthony J

    2004-01-01

    An 80-year-old man, who is an experienced artist, underwent orbital exenteration for invasive squamous cell carcinoma. After exenteration, the patient noted a persistent, colored visual phenomenon. The phantom vision continued unchanged to 9 months after surgery (the time of writing), when the patient presented a graphic and written description of phantom vision.

  4. Putting the Vision into Practice

    ERIC Educational Resources Information Center

    Ravenhall, Mark

    2010-01-01

    It's almost a year since the revolution--the "Learning Revolution," that is. This was the Government's long-term vision for the development of "informal adult learning", as laid out in the White Paper of March 2009. The vision was expansive, embracing informal learning in the workplace, promoting a "new" culture of…

  5. An overview of computer vision

    NASA Technical Reports Server (NTRS)

    Gevarter, W. B.

    1982-01-01

    An overview of computer vision is provided. Image understanding and scene analysis are emphasized, and pertinent aspects of pattern recognition are treated. The basic approach to computer vision systems, the techniques utilized, applications, the current existing systems and state-of-the-art issues and research requirements, who is doing it and who is funding it, and future trends and expectations are reviewed.

  6. Putting the Vision into Practice

    ERIC Educational Resources Information Center

    Ravenhall, Mark

    2010-01-01

    It's almost a year since the revolution--the "Learning Revolution," that is. This was the Government's long-term vision for the development of "informal adult learning", as laid out in the White Paper of March 2009. The vision was expansive, embracing informal learning in the workplace, promoting a "new" culture of…

  7. Vision by Man and Machine.

    ERIC Educational Resources Information Center

    Poggio, Tomaso

    1984-01-01

    Studies of stereo vision guide research on how animals see and how computers might accomplish this human activity. Discusses a sequence of algorithms to first extract information from visual images and then to calculate the depths of objects in the three-dimensional world, concentrating on stereopsis (stereo vision). (JN)

  8. Vision in albinism.

    PubMed Central

    Summers, C G

    1996-01-01

    PURPOSE: The purpose of this investigation was to study vision in albinism from 3 perspectives: first, to determine the characteristics of grating acuity development in children with albinism; second, to study the effect of illumination on grating acuity; and third, to define the effect of melanin pigment in the macula on visual acuity. METHODS: I. Binocular and monocular grating acuity was measured with the acuity card procedure in 40 children with albinism during the first 3 years of life. Recognition acuity was eventually measured in 27 of these patients. Ocular pigment was documented by a previously established method of grading iris transillumination and macular transparency. II. Grating acuity under standard and increased illumination levels was measured in 20 adults with albinism (group I) compared with that in 20 adults with nystagmus due to conditions other than albinism (group II) and 20 adults without ocular abnormalities (group III). Recognition acuity measured with the ETDRS charts was also recorded for each group. III. Best-corrected binocular acuity was measured in 29 patients with albinism who were identified with melanin pigment in their maculas by direct ophthalmoscopy. RESULTS: I. Both binocular and monocular grating acuity was reduced 2 to 3 octaves below the norm for ages 6 months to 3 years. Limited data available in the first 6 months of life did not show failure of vision to develop. Grating acuity measurements overestimated eventual recognition acuity. Mean recognition acuity was 20/111. A relationship between grating acuity development and presence or absence of ocular pigment was not found. II. Grating acuity was significantly better for groups I and II under the condition of increased illumination (P < .03). For patients with albinism, grating acuity under standard illumination was significantly better than recognition acuity (P < .001). For all groups, grating acuity under increased illumination was significantly better than recognition

  9. Vision and vestibular adaptation.

    PubMed

    Demer, J L; Crane, B T

    1998-07-01

    This article summarizes six recent degree-of-freedom studies of visual-vestibular interaction during natural activities and relates the findings to canal-otolith interactions evaluated during eccentric axis rotations. Magnetic search coils were used to measure angular eye and head movements of young and elderly subjects. A flux gate magnetometer was used to measure three-dimensional head translation. Three activities were studied: standing quietly, walking in place, and running in place. Each activity was evaluated with three viewing conditions: a visible target viewed normally, a remembered target in darkness, and a visible target viewed with x2 binocular telescopic spectacles. Canal-otolith interaction was assessed with passive, whole-body, transient, and steady-state rotations in pitch and yaw at multiple frequencies about axes that were either oculocentric or eccentric to the eyes. For each rotational axis, subjects regarded visible and remembered targets located at various distances. Horizontal and vertical angular vestibulo-ocular reflexes were demonstrable in all subjects during standing, walking, and running. When only angular gains were considered, gains in both darkness and during normal vision were less than 1.0 and were generally lower in elderly than in young subjects. Magnified vision with x2 telescopic spectacles produced only small gain increases as compared with normal vision. During walking and running all subjects exhibited significant mediolateral and dorsoventral head translations that were antiphase locked to yaw and pitch head movements, respectively. These head translations and rotations have mutually compensating effects on gaze in a target plane for typical viewing distances and allow angular vestibulo-ocular reflex gains of less than 1.0 to be optimal for gaze stabilization during natural activities. During passive, whole-body eccentric pitch and yaw head rotations, vestibulo-ocular reflex gain was modulated as appropriate to stabilize

  10. Understanding Your Vision: The "Imperfect Eye"

    MedlinePlus

    ... Navigation Bar Home Current Issue Past Issues Feature: Vision Understanding Your Vision: The "Imperfect Eye" Past Issues / Summer 2008 Table ... are different and so are the types of vision that we have. Understanding how some of us ...

  11. Peripheral Vision Varies from Person to Person

    MedlinePlus

    ... https://medlineplus.gov/news/fullstory_164630.html Peripheral Vision Varies From Person to Person And 'bad spots' ... left side? A bad spot in your peripheral vision may be to blame. Peripheral vision is the ...

  12. Vision Problems in the U.S.

    MedlinePlus

    ... Eye Emergencies How to Jump Start a Car Battery Safely Electronic Screens and Your Eyes Nutrition and ... External Resources The Cost of Vision Problems The Future of Vision Vision Problems in the U.S. Healthy ...

  13. Corneoplastique: art of vision surgery.

    PubMed

    Gulani, Arun C

    2014-01-01

    Corneoplastique incorporates the entire spectrum of Vision corrective surgery including Lasik, premium cataract surgery, corneal surgery, ocular surface surgery and the full range of anterior segment surgery itself in manipulating the optics of every eye towards unaided emmetropia to define each and every eye surgeon as a "Vision Corrective Surgeon". This concept of approaching each case individually and designing vision therewith enables surgeons to correct not only virgin eyes but also approach complex cases and complications with the goal of 20/20 vision. Armed with this holistic approach, eye surgeons can use minimally invasive, aesthetically pleasing and visually focused surgery in single or staged process aiming for each patient's Best Vision Potential (BVP) raising eye surgery itself then to an Art!

  14. Corneoplastique™: Art of vision surgery

    PubMed Central

    Gulani, Arun C

    2014-01-01

    Corneoplastique incorporates the entire spectrum of Vision corrective surgery including Lasik, premium cataract surgery, corneal surgery, ocular surface surgery and the full range of anterior segment surgery itself in manipulating the optics of every eye towards unaided emmetropia to define each and every eye surgeon as a “Vision Corrective Surgeon”. This concept of approaching each case individually and designing vision therewith enables surgeons to correct not only virgin eyes but also approach complex cases and complications with the goal of 20/20 vision. Armed with this holistic approach, eye surgeons can use minimally invasive, aesthetically pleasing and visually focused surgery in single or staged process aiming for each patient's Best Vision Potential (BVP) raising eye surgery itself then to an Art! PMID:24492495

  15. 3D vision system assessment

    NASA Astrophysics Data System (ADS)

    Pezzaniti, J. Larry; Edmondson, Richard; Vaden, Justin; Hyatt, Bryan; Chenault, David B.; Kingston, David; Geulen, Vanilynmae; Newell, Scott; Pettijohn, Brad

    2009-02-01

    In this paper, we report on the development of a 3D vision system consisting of a flat panel stereoscopic display and auto-converging stereo camera and an assessment of the system's use for robotic driving, manipulation, and surveillance operations. The 3D vision system was integrated onto a Talon Robot and Operator Control Unit (OCU) such that direct comparisons of the performance of a number of test subjects using 2D and 3D vision systems were possible. A number of representative scenarios were developed to determine which tasks benefited most from the added depth perception and to understand when the 3D vision system hindered understanding of the scene. Two tests were conducted at Fort Leonard Wood, MO with noncommissioned officers ranked Staff Sergeant and Sergeant First Class. The scenarios; the test planning, approach and protocols; the data analysis; and the resulting performance assessment of the 3D vision system are reported.

  16. Vision for 2020.

    PubMed

    Giles, Laura; Brewer, E Thomas; Mosqueda, Laura; Huba, George J; Melchior, Lisa A

    2010-07-01

    This article reflects the collective thoughts of the 20 projects supported by the Archstone Foundation Elder Abuse and Neglect Initiative on offering a vision for improving the response system for elder abuse and, in turn, the lives of older adults between now and the year 2020. Five key areas were identified as critically important for advancing the field in the next ten years: (a) increased public awareness and shifting public attitudes, (b) improved identification and triage of cases, (c) increased integrated service models, (d) improved justice system response, and (e) leveraging and utilizing emerging and untapped resources. The lessons learned from the experiences of these 20 projects in California can serve as demonstration models for other communities to adopt, adapt, and improve response systems for elder abuse and neglect.

  17. Multiparameter vision testing apparatus

    NASA Technical Reports Server (NTRS)

    Hunt, S. R., Jr.; Homkes, R. J.; Poteate, W. B.; Sturgis, A. C. (Inventor)

    1975-01-01

    Compact vision testing apparatus is described for testing a large number of physiological characteristics of the eyes and visual system of a human subject. The head of the subject is inserted into a viewing port at one end of a light-tight housing containing various optical assemblies. Visual acuity and other refractive characteristics and ocular muscle balance characteristics of the eyes of the subject are tested by means of a retractable phoroptor assembly carried near the viewing port and a film cassette unit carried in the rearward portion of the housing (the latter selectively providing a variety of different visual targets which are viewed through the optical system of the phoroptor assembly). The visual dark adaptation characteristics and absolute brightness threshold of the subject are tested by means of a projector assembly which selectively projects one or both of a variable intensity fixation target and a variable intensity adaptation test field onto a viewing screen located near the top of the housing.

  18. Autophagy supports color vision.

    PubMed

    Zhou, Zhenqing; Vinberg, Frans; Schottler, Frank; Doggett, Teresa A; Kefalov, Vladimir J; Ferguson, Thomas A

    2015-01-01

    Cones comprise only a small portion of the photoreceptors in mammalian retinas. However, cones are vital for color vision and visual perception, and their loss severely diminishes the quality of life for patients with retinal degenerative diseases. Cones function in bright light and have higher demand for energy than rods; yet, the mechanisms that support the energy requirements of cones are poorly understood. One such pathway that potentially could sustain cones under basal and stress conditions is macroautophagy. We addressed the role of macroautophagy in cones by examining how the genetic block of this pathway affects the structural integrity, survival, and function of these neurons. We found that macroautophagy was not detectable in cones under normal conditions but was readily observed following 24 h of fasting. Consistent with this, starvation induced phosphorylation of AMPK specifically in cones indicating cellular starvation. Inhibiting macroautophagy in cones by deleting the essential macroautophagy gene Atg5 led to reduced cone function following starvation suggesting that cones are sensitive to systemic changes in nutrients and activate macroautophagy to maintain their function. ATG5-deficiency rendered cones susceptible to light-induced damage and caused accumulation of damaged mitochondria in the inner segments, shortening of the outer segments, and degeneration of all cone types, revealing the importance of mitophagy in supporting cone metabolic needs. Our results demonstrate that macroautophagy supports the function and long-term survival of cones providing for their unique metabolic requirements and resistance to stress. Targeting macroautophagy has the potential to preserve cone-mediated vision during retinal degenerative diseases.

  19. Autophagy supports color vision

    PubMed Central

    Zhou, Zhenqing; Vinberg, Frans; Schottler, Frank; Doggett, Teresa A; Kefalov, Vladimir J; Ferguson, Thomas A

    2015-01-01

    Cones comprise only a small portion of the photoreceptors in mammalian retinas. However, cones are vital for color vision and visual perception, and their loss severely diminishes the quality of life for patients with retinal degenerative diseases. Cones function in bright light and have higher demand for energy than rods; yet, the mechanisms that support the energy requirements of cones are poorly understood. One such pathway that potentially could sustain cones under basal and stress conditions is macroautophagy. We addressed the role of macroautophagy in cones by examining how the genetic block of this pathway affects the structural integrity, survival, and function of these neurons. We found that macroautophagy was not detectable in cones under normal conditions but was readily observed following 24 h of fasting. Consistent with this, starvation induced phosphorylation of AMPK specifically in cones indicating cellular starvation. Inhibiting macroautophagy in cones by deleting the essential macroautophagy gene Atg5 led to reduced cone function following starvation suggesting that cones are sensitive to systemic changes in nutrients and activate macroautophagy to maintain their function. ATG5-deficiency rendered cones susceptible to light-induced damage and caused accumulation of damaged mitochondria in the inner segments, shortening of the outer segments, and degeneration of all cone types, revealing the importance of mitophagy in supporting cone metabolic needs. Our results demonstrate that macroautophagy supports the function and long-term survival of cones providing for their unique metabolic requirements and resistance to stress. Targeting macroautophagy has the potential to preserve cone-mediated vision during retinal degenerative diseases. PMID:26292183

  20. Vision Sensors and Cameras

    NASA Astrophysics Data System (ADS)

    Hoefflinger, Bernd

    Silicon charge-coupled-device (CCD) imagers have been and are a specialty market ruled by a few companies for decades. Based on CMOS technologies, active-pixel sensors (APS) began to appear in 1990 at the 1 μm technology node. These pixels allow random access, global shutters, and they are compatible with focal-plane imaging systems combining sensing and first-level image processing. The progress towards smaller features and towards ultra-low leakage currents has provided reduced dark currents and μm-size pixels. All chips offer Mega-pixel resolution, and many have very high sensitivities equivalent to ASA 12.800. As a result, HDTV video cameras will become a commodity. Because charge-integration sensors suffer from a limited dynamic range, significant processing effort is spent on multiple exposure and piece-wise analog-digital conversion to reach ranges >10,000:1. The fundamental alternative is log-converting pixels with an eye-like response. This offers a range of almost a million to 1, constant contrast sensitivity and constant colors, important features in professional, technical and medical applications. 3D retino-morphic stacking of sensing and processing on top of each other is being revisited with sub-100 nm CMOS circuits and with TSV technology. With sensor outputs directly on top of neurons, neural focal-plane processing will regain momentum, and new levels of intelligent vision will be achieved. The industry push towards thinned wafers and TSV enables backside-illuminated and other pixels with a 100% fill-factor. 3D vision, which relies on stereo or on time-of-flight, high-speed circuitry, will also benefit from scaled-down CMOS technologies both because of their size as well as their higher speed.

  1. Old Night Vision Meets New

    NASA Image and Video Library

    2017-09-27

    NASA image acquired November 11-12, 2012. On November 12, 2012, the Visible Infrared Imaging Radiometer Suite (VIIRS) on the Suomi NPP satellite captured the top nighttime image of city, village, and highway lights near Delhi, India. For comparison, the lower image shows the same area one night earlier, as observed by the Operational Line Scan (OLS) system on a Defense Meteorological Satellite Program (DMSP) spacecraft. Since the 1960s, the U.S. Air Force has operated DMSP in order to observe clouds and other weather variables in key wavelengths of infrared and visible light. Since 1972, the DMSP satellites have included the Operational Linescan System (OLS), which gives weather forecasters some ability to see in the dark. It has been a highly successful sensor, but it is dependent on older technology with lower resolution than most scientists would like. And for many years, DMSP data were classified. Through improved optics and “smart” sensing technology, the VIIRS “day-night band,” is ten to fifteen times better than the OLS system at resolving the relatively dim lights of human settlements and reflected moonlight. Each VIIRS pixel shows roughly 740 meters (0.46 miles) across, compared to the 3-kilometer footprint (1.86 miles) of DMSP. Beyond the resolution, the new sensor can detect dimmer light sources. And since the VIIRS measurements are fully calibrated (unlike DMSP), scientists now have the precision required to make quantitative measurements of clouds and other features. “In contrast to the Operational Line Scan system, the imagery from the new day-night band is almost like a nearsighted person putting on glasses for the first time and looking at the Earth anew,” says Steve Miller, an atmospheric scientist at Colorado State University. “VIIRS has allowed us to bring this coarse, blurry view of night lights into clearer focus. Now we can see things in such great detail and at such high precision that we’re really talking about a new kind of

  2. The World Water Vision: From Developing a Vision to Action

    NASA Astrophysics Data System (ADS)

    Gangopadhyay, S.; Cosgrove, W.; Rijsberman, F.; Strzepek, K.; Strzepek, K.

    2001-05-01

    The World Water Vision exercise was initiated by the World Water Commission under the auspices of the World Water Council. The goal of the World Water Vision project was to develop a widely shared vision on the actions required to achieve a common set of water-related goals and the necessary commitment to carry out these actions. The Vision should be participatory in nature, including input from both developed and developing regions, with a special focus on the needs of the poor, women, youth, children and the environment. Three overall objectives were to: (i)raise awareness of water issues among both the general population and decision-makers so as to foster the necessary political will and leadership to tackle the problems seriously and systematically; (ii) develop a vision of water management for 2025 that is shared by water sector specialists as well as international, national and regional decision-makers in government, the private sector and civil society; and (iii) provide input to a Framework for Action to be elaborated by the Global Water Partnership, with steps to go from vision to action, including recommendations to funding agencies for investment priorities. This exercise was characterized by the principles of: (i) a participatory approach with extensive consultation; (ii) Innovative thinking; (iii) central analysis to assure integration and co-ordination; and (iv) emphasis on communication with groups outside the water sector. The primary activities included, developing global water scenarios that fed into regional consultations and sectoral consultations as water for food, water for people - water supply and sanitation, and water and environment. These consultations formulated the regional and sectoral visions that were synthesized to form the World Water Vision. The findings from this exercise were reported and debated at the Second World Water Forum and the Ministerial Conference held in The Hague, The Netherlands during April 2000. This paper

  3. Clinical effect of low vision aids.

    PubMed

    Ji, Y H; Park, H J; Oh, S Y

    1999-06-01

    The number of patients with low vision is increasing as life expectancy increases. In addition, the interest and demand for low vision aids are also increasing with improved socioeconomic status and the development of mass media. Therefore, it is imperative to recognize the importance of low vision aids. We reviewed the clinical records of 118 patients who visited our low vision clinic more than twice. According to the data analyzed, optic nerve atrophy, retinal degeneration, diabetic retinopathy and age-related macular degeneration were the most common causes of low vision in these patients. The best corrected visual acuities without low vision aids were less than 0.3, but with the help of low vision aids, vision improved to more than 0.4 in 87% of the patients for near vision, and 56% for distant vision. The patients had complained that they could not read books, see a blackboard, recognize a person at a distance, and had other problems because of low vision. However, with the use of low vision aids their satisfaction with their vision rose to 70%. Hand magnifiers, high-powered spectacle lenses, and stand magnifiers were the low vision aids commonly used by people for near vision, while the Galilean telescope and Keplerian telescope were the most popular devices used for distant vision. In conclusion, low vision aids are very helpful devices to patients with low vision.

  4. Machine vision for digital microfluidics.

    PubMed

    Shin, Yong-Jun; Lee, Jeong-Bong

    2010-01-01

    Machine vision is widely used in an industrial environment today. It can perform various tasks, such as inspecting and controlling production processes, that may require humanlike intelligence. The importance of imaging technology for biological research or medical diagnosis is greater than ever. For example, fluorescent reporter imaging enables scientists to study the dynamics of gene networks with high spatial and temporal resolution. Such high-throughput imaging is increasingly demanding the use of machine vision for real-time analysis and control. Digital microfluidics is a relatively new technology with expectations of becoming a true lab-on-a-chip platform. Utilizing digital microfluidics, only small amounts of biological samples are required and the experimental procedures can be automatically controlled. There is a strong need for the development of a digital microfluidics system integrated with machine vision for innovative biological research today. In this paper, we show how machine vision can be applied to digital microfluidics by demonstrating two applications: machine vision-based measurement of the kinetics of biomolecular interactions and machine vision-based droplet motion control. It is expected that digital microfluidics-based machine vision system will add intelligence and automation to high-throughput biological imaging in the future.

  5. Machine vision for digital microfluidics

    NASA Astrophysics Data System (ADS)

    Shin, Yong-Jun; Lee, Jeong-Bong

    2010-01-01

    Machine vision is widely used in an industrial environment today. It can perform various tasks, such as inspecting and controlling production processes, that may require humanlike intelligence. The importance of imaging technology for biological research or medical diagnosis is greater than ever. For example, fluorescent reporter imaging enables scientists to study the dynamics of gene networks with high spatial and temporal resolution. Such high-throughput imaging is increasingly demanding the use of machine vision for real-time analysis and control. Digital microfluidics is a relatively new technology with expectations of becoming a true lab-on-a-chip platform. Utilizing digital microfluidics, only small amounts of biological samples are required and the experimental procedures can be automatically controlled. There is a strong need for the development of a digital microfluidics system integrated with machine vision for innovative biological research today. In this paper, we show how machine vision can be applied to digital microfluidics by demonstrating two applications: machine vision-based measurement of the kinetics of biomolecular interactions and machine vision-based droplet motion control. It is expected that digital microfluidics-based machine vision system will add intelligence and automation to high-throughput biological imaging in the future.

  6. Surgical treatment of low vision.

    PubMed

    Gorfinkel, John

    2006-06-01

    Recent advances in technology are driving a renewed search to find surgical solutions for low vision rehabilitation. The scope of surgery is now being pushed beyond the initial goal of repairing existing anatomical structures. Today, the goal for vision rehabilitation is no less than replacing damaged ocular tissues with artificial ones. Surgical management of low vision may be subdivided into two categories, those procedures aimed at restoring ultrastructural visual function and those aimed at enhancing visual acuity of the residual retina with various levels of magnification. This paper briefly reviews advances in ultrastructural restoration by repair and considers in more detail enhanced acuity through magnification or replacement.

  7. Vision Therapy for Post-Concussion Vision Disorders.

    PubMed

    Gallaway, Michael; Scheiman, Mitchell; Mitchell, G Lynn

    2017-01-01

    To determine the frequency and types of vision disorders associated with concussion, and to determine the success rate of vision therapy for these conditions in two private practice settings. All records over an 18-month period of patients referred for post-concussion vision problems were reviewed from two private practices. Diagnoses of vergence, accommodative, or eye movement disorders were based on pre-established, clinical criteria. Vision therapy was recommended based on clinical findings and symptoms. Two hundred eighteen patient records were found with a diagnosis of concussion. Fifty-six percent of the concussions were related to sports, 20% to automobile accidents, and 24% to school, work, or home-related incidents. The mean age was 20.5 years and 58% were female. Eighty-two percent of the patients had a diagnosis of an oculomotor problem [binocular problems (62%), accommodative problems (54%), eye movement problems (21%)]. The most prevalent diagnoses were convergence insufficiency (CI, 47%) and accommodative insufficiency (AI, 42%). Vision therapy was recommended for 80% of the patients. Forty-six per cent (80/175) either did not pursue treatment or did not complete treatment. Of the 54% (95/175) who completed therapy, 85% of patients with CI were successful and 15% were improved, and with AI, 33% were successful and 67% improved. Clinically and statistically significant changes were measured in symptoms, near point of convergence, positive fusional vergence, and accommodative amplitude. In this case series, post-concussion vision problems were prevalent and CI and AI were the most common diagnoses. Vision therapy had a successful or improved outcome in the vast majority of cases that completed treatment. Evaluation of patients with a history of concussion should include testing of vergence, accommodative, and eye movement function. Prospective clinical trials are necessary to assess the natural history of concussion-related vision disorders and

  8. Vision with the AN/PVS-5 Night Vision Goggles

    DTIC Science & Technology

    1976-04-08

    stereopsis in avia- tion are still somewhat equivocal. Two recent reports1 3 ,14 have shown that landing performances of pilots deprived of vision in one eye...btock ntanb~v) AN/PV’S-5 Night Vision Goggle Relative Depth Perception Stereopsis Visual Modulation Transfer Function 20. ITRACT (Cent Iaus an roer**e...aided monocular performances (Table 1). The Howard-Dolman apparatus is usually considered to yield measurts of central stereopsis . Relative depth

  9. Computer_Vision

    SciTech Connect

    Justin Doak, LANL

    2002-10-04

    The Computer_Vision software performs object recognition using a novel multi-scale characterization and matching algorithm. To understand the multi-scale characterization and matching software, it is first necessary to understand some details of the Computer Vision (CV) Project. This project has focused on providing algorithms and software that provide an end-to-end toolset for image processing applications. At a high-level, this end-to-end toolset focuses on 7 coy steps. The first steps are geometric transformations. 1) Image Segmentation. This step essentially classifies pixels in foe input image as either being of interest or not of interest. We have also used GENIE segmentation output for this Image Segmentation step. 2 Contour Extraction (patent submitted). This takes the output of Step I and extracts contours for the blobs consisting of pixels of interest. 3) Constrained Delaunay Triangulation. This is a well-known geometric transformation that creates triangles inside the contours. 4 Chordal Axis Transform (CAT) . This patented geometric transformation takes the triangulation output from Step 3 and creates a concise and accurate structural representation of a contour. From the CAT, we create a linguistic string, with associated metrical information, that provides a detailed structural representation of a contour. 5.) Normalization. This takes an attributed linguistic string output from Step 4 and balances it. This ensures that the linguistic representation accurately represents the major sections of the contour. Steps 6 and 7 are implemented by the multi-scale characterization and matching software. 6) Multi scale Characterization. This takes as input the attributed linguistic string output from Normalization. Rules from a context free grammar are applied in reverse to create a tree-like representation for each contour. For example, one of the grammar’s rules is L -> (LL ). When an (LL) is seen in a string, a parent node is created that points to the four

  10. [Inherited colour vision deficiencies--from Dalton to molecular genetics].

    PubMed

    Cvetković, Dragana; Cvetković, Dobrosav

    2005-01-01

    In recent years, great advances have been made in our understanding of the molecular basis of colour vision defects, as well as of the patterns of genetic variation in individuals with normal colour vision. Molecular genetic analyses have explained the diversity of types and degrees of severity in colour vision anomalies, their frequencies, pronounced individual variations in test results, etc. New techniques have even enabled the determination of John Dalton's real colour vision defect, 150 years after his death. Inherited colour vision deficiencies most often result from the mutations of genes that encode cone opsins. Cone opsin genes are linked to chromosomes 7 (the S or "blue" gene) and X (the L or "red" gene and the M or "green" gene). The L and M genes are located on the q arm of the X chromosome in a head-to-tail array, composed of 2 to 6 (typically 3) genes--a single L is followed by one or more M genes. Only the first two genes of the array are expressed and contribute to the colour vision phenotype. The high degree of homology (96%) between the L and M genes predisposes them to unequal recombination, leading to gene deletion or the formation of hybrid genes (comprising portions of both the L and M genes), explaining the majority of the common red-green colour vision deficiencies. The severity of any deficiency is influenced by the difference in spectral sensitivity between the opsins encoded by the first two genes of the array. A rare defect, S monochromacy, is caused either by the deletion of the regulatory region of the array or by mutations that inactivate the L and M genes. Most recent research concerns the molecular basis of complete achromatopsia, a rare disorder that involves the complete loss of all cone function. This is not caused by mutations in opsin genes, but in other genes that encode cone-specific proteins, e.g. channel proteins and transducin.

  11. Vision as a Beachhead.

    PubMed

    Heeger, David J; Behrmann, Marlene; Dinstein, Ilan

    2016-09-29

    When neural circuits develop abnormally due to different genetic deficits and/or environmental insults, neural computations and the behaviors that rely on them are altered. Computational theories that relate neural circuits with specific quantifiable behavioral and physiological phenomena, therefore, serve as extremely useful tools for elucidating the neuropathological mechanisms that underlie different disorders. The visual system is particularly well suited for characterizing differences in neural computations; computational theories of vision are well established, and empirical protocols for measuring the parameters of those theories are well developed. In this article, we examine how psychophysical and neuroimaging measurements from human subjects are being used to test hypotheses about abnormal neural computations in autism, with an emphasis on hypotheses regarding potential excitation/inhibition imbalances. We discuss the complexity of relating specific computational abnormalities to particular underlying mechanisms given the diversity of neural circuits that can generate the same computation, and we discuss areas of research in which computational theories need to be further developed to provide useful frameworks for interpreting existing results. A final emphasis is placed on the need to extend existing ideas into developmental frameworks that take into account the dramatic developmental changes in neurophysiology (e.g., changes in excitation/inhibition balance) that take place during the first years of life, when autism initially emerges.

  12. Vision without knowledge.

    PubMed Central

    Milner, A D

    1997-01-01

    A brain-damaged patient (D.F.) with visual form agnosia is described and discussed. D.F. has a profound inability to recognize objects, places and people, in large part because of her inability to make perceptual discriminations of size, shape or orientation, despite having good visual acuity. Yet she is able to perform skilled actions that depend on that very same size, shape and orientation information that is missing from her perceptual awareness. It is suggested that her intact vision can best be understood within the framework of a dual processing model, according to which there are two cortical processing streams operating on different coding principles, for perception and for action, respectively. These may be expected to have different degrees of dependence on top-down information. One possibility is that D.F.'s lack of explicit awareness of the visual cues that guide her behaviour may result from her having to rely on a processing system which is not knowledge-based in a broad sense. Conversely, it may be that the perceptual system can provide conscious awareness of its products in normal individuals by virtue of the fact that it does interact with a stored base of visual knowledge. PMID:9304691

  13. The Earth Science Vision

    NASA Technical Reports Server (NTRS)

    Schoeberl, Mark; Rychekewkitsch, Michael; Andrucyk, Dennis; McConaughy, Gail; Meeson, Blanche; Hildebrand, Peter; Einaudi, Franco (Technical Monitor)

    2000-01-01

    NASA's Earth Science Enterprise's long range vision is to enable the development of a national proactive environmental predictive capability through targeted scientific research and technological innovation. Proactive environmental prediction means the prediction of environmental events and their secondary consequences. These consequences range from disasters and disease outbreak to improved food production and reduced transportation, energy and insurance costs. The economic advantage of this predictive capability will greatly outweigh the cost of development. Developing this predictive capability requires a greatly improved understanding of the earth system and the interaction of the various components of that system. It also requires a change in our approach to gathering data about the earth and a change in our current methodology in processing that data including its delivery to the customers. And, most importantly, it requires a renewed partnership between NASA and its sister agencies. We identify six application themes that summarize the potential of proactive environmental prediction. We also identify four technology themes that articulate our approach to implementing proactive environmental prediction.

  14. Spatiochromatic model of vision

    NASA Astrophysics Data System (ADS)

    Moorhead, Ian R.

    1996-04-01

    A computer model of human spatiochromatic vision, based on the scheme proposed by De Valois and De Valois has been developed. The implementation of the model enables true color 2-D images to be processed. The input consists of cone signals at each pixel. Subsequent levels of the model are represented by arrays of activity corresponding to the equivalent neural activity. The implementation allows the behavior of different stages of the model -- retinal and cortical -- to be studied with different varieties of spatial and chromatic stimuli of any complexity. In addition the model is extensible to allow different types of neural mechanisms and cortical demultiplexing processes to be incorporated. As well as providing qualitative insight into the operation of the different stages of the model the implementation also permits quantitative predictions to be made. Both increment threshold and hue naming results are predicted by the model, but the accuracy of these predictions is contingent upon an appropriate choice of adaptation state at the retinal cone and ganglion cell level.

  15. The Earth Science Vision

    NASA Technical Reports Server (NTRS)

    Schoeberl, Mark; Rychekewkitsch, Michael; Andrucyk, Dennis; McConaughy, Gail; Meeson, Blanche; Hildebrand, Peter; Einaudi, Franco (Technical Monitor)

    2000-01-01

    NASA's Earth Science Enterprise's long range vision is to enable the development of a national proactive environmental predictive capability through targeted scientific research and technological innovation. Proactive environmental prediction means the prediction of environmental events and their secondary consequences. These consequences range from disasters and disease outbreak to improved food production and reduced transportation, energy and insurance costs. The economic advantage of this predictive capability will greatly outweigh the cost of development. Developing this predictive capability requires a greatly improved understanding of the earth system and the interaction of the various components of that system. It also requires a change in our approach to gathering data about the earth and a change in our current methodology in processing that data including its delivery to the customers. And, most importantly, it requires a renewed partnership between NASA and its sister agencies. We identify six application themes that summarize the potential of proactive environmental prediction. We also identify four technology themes that articulate our approach to implementing proactive environmental prediction.

  16. Taking Care of Your Vision

    MedlinePlus

    ... Health Food & Fitness Diseases & Conditions Infections Q&A School & Jobs Drugs & Alcohol Staying Safe Recipes En Español ... Activities Choosing the Right Sport for You Healthy School Lunch Planner Taking Care of Your Vision KidsHealth > ...

  17. Do You Have Cultural Vision?

    ERIC Educational Resources Information Center

    Gonzalez-Mena, Janet

    1991-01-01

    Maintains that child care teachers can help remedy cultural tunnel vision by promoting cultural diversity and understanding as they work with children and communicate with parents about what they are doing. (BB)

  18. Bringing Vision Problems into Focus. Health Alert.

    ERIC Educational Resources Information Center

    Learning, 1996

    1996-01-01

    Many students have undiagnosed vision problems despite passing school vision screening. Traditional screening may miss problems with close vision, eye-hand coordination, and smooth eye coordination. The article discusses what teachers should look for, how to proceed if there is a problem, and how to create vision-friendly classrooms. A list of…

  19. Geometric Modeling for Computer Vision

    DTIC Science & Technology

    1974-10-01

    Vision and Artificial Intellegence could lead to robots, androids and cyborgs which will be able to see, to think and to feel conscious 10.4...the construction of computer representations of physical objects, cameras, images and light for the sake of simulating their behavior. In Artificial ...specifically, I wish to exclude the connotation that the theory is a natural theory of vision. Perhaps there can be such a thing as an artificial theory

  20. Robot Motion Vision by Fixation

    DTIC Science & Technology

    1992-09-01

    55 7 Spatial and Temporal Brightness Gradients 57 7.1 Visual Representation ........ .......................... 57 7.2 Interpretation and...computer vision scientists have been working on the development of artificial systems for performing different visual tasks. 1.1 Motion Vision In many...implementation errors [70, 72]. * Representing image gradients: A novel method has been presented for visual representation of the spatio-ttmporal gradients

  1. Computational Vision: A Critical Review

    DTIC Science & Technology

    1989-10-01

    Intelligence Laboratory, Massachusetts Institute of Technology, 1988. [58] A. L. Hodgkin and A. F. Huxley . A quantitative description of membrane current and...respectively, and in section 2.4 we review some of the aspects of neuronal modeling in the context of vision. 2.1 Low-level vision One possible definition of...many potential target matches, all but one of which are false. Two constraints on matching were proposed to solve the false targets problem [95]. The

  2. Intelligent robots and computer vision

    SciTech Connect

    Casasent, D.P.

    1985-01-01

    This book presents the papers given at a conference which examined artificial intelligence and image processing in relation to robotics. Topics considered at the conference included feature extraction and pattern recognition for computer vision, image processing for intelligent robotics, robot sensors, image understanding and artificial intelligence, optical processing techniques in robotic applications, robot languages and programming, processor architectures for computer vision, mobile robots, multisensor fusion, three-dimensional modeling and recognition, intelligent robots applications, and intelligent robot systems.

  3. Adaptive machine vision. Annual report

    SciTech Connect

    Stoner, W.W.; Brill, M.H.; Bergeron, D.W.

    1988-03-08

    The mission of the Strategic Defense Initiative is to develop defenses against threatening ballistic missiles. There are four distinct phases to the SDI defense; boost, post-boost, midcourse and terminal. In each of these phases, one or more machine-vision functions are required, such as pattern recognition, stereo image fusion, clutter rejection and discrimination. The SDI missions of coarse track, stereo track and discrimination are examined here from the point of view of a machine-vision system.

  4. Aircraft cockpit vision: Math model

    NASA Technical Reports Server (NTRS)

    Bashir, J.; Singh, R. P.

    1975-01-01

    A mathematical model was developed to describe the field of vision of a pilot seated in an aircraft. Given the position and orientation of the aircraft, along with the geometrical configuration of its windows, and the location of an object, the model determines whether the object would be within the pilot's external vision envelope provided by the aircraft's windows. The computer program using this model was implemented and is described.

  5. [Acquired disorders of color vision].

    PubMed

    Lascu, Lidia; Balaş, Mihaela

    2002-01-01

    This article is a general view of acquired disorders of color vision. The revision of the best known methods and of the etiopathogenic classification is not very important in ophthalmology but on the other hand, the detection of the blue defect advertise and associated ocular pathology. There is a major interest in serious diseases as multiple sclerosis, AIDS, diabetes melitus, when the first ocular sign can be a defect in the color vision.

  6. Strategic Vision: A Selected Bibliography

    DTIC Science & Technology

    2008-03-01

    STRATEGIC VISION A Selected Bibliography U.S. ARMY WAR COLLEGE LIBRARY March 2008 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public...please see the bibliography titled Strategic Vision: A Selected Bibliogra- phy, dated July 2004. All items are available through the USAWC Library ...For your convenience, at the end of the entries, we have added Library call numbers, Internet addresses, or database links. Call numbers indicate the

  7. [Vision measurement and psychophysical tests].

    PubMed

    Kronbauer, Airton Leite; Schor, Paulo; Carvalho, Luis Alberto Vieira de

    2008-01-01

    Vision measurement is the basis for the study and standardization of visual sciences. Measurement of visual acuity has great value for research and for clinical practice. This paper (1) reviews the fundamental concepts to understand visual sense and the measuring units; (2) presents the fundamental limits to visual performance and the principles of aberration measurement of the eye; and (3) discusses methods for measuring and classifying vision with new technologies.

  8. Suggestive modeling for machine vision

    NASA Astrophysics Data System (ADS)

    Fitzgibbon, Andrew W.; Fisher, Robert B.

    1992-11-01

    Traditional modeling techniques, with roots in CAD systems, do not provide a rich enough modeling environment for computer vision. The models themselves describe the structure rather than appearance of objects, and rarely provide facilities for the recording of the additional information required by a vision system. Encoding appearance explicitly ensures quick access and use of the model, and yields model features that correspond to observable data features. We describe the Suggestive Modelling System (SMS) which has been designed specifically for vision applications, combining the geometric object model with vision-specific annotations. Among SMS's features are: (1) A novel separation of surface shape, extent and position; (2) Encoding of underconstrained positions for subcomponents such as spheres and discs; (3) Incorporation of uncertain property values; (4) Cheap encoding of viewpoint- dependent information in addition to the body-centered model; (5) Hierarchical models; (6) Symbolic labels for each primitive; and (7) Parallel curve, surface, and volume-based representations simplify project management. We will describe how this approach reflects more faithfully the capabilities of current scene analysis algorithms than traditional methods. Results from the Imagine 2 vision system demonstrate the applicability of the models to complex real-world industrial inspection and recognition tasks. In addition a number of other vision-related applications in which the SMS paradigm has proved useful will be discussed.

  9. Computer vision syndrome: a review.

    PubMed

    Blehm, Clayton; Vishnu, Seema; Khattak, Ashbala; Mitra, Shrabanee; Yee, Richard W

    2005-01-01

    As computers become part of our everyday life, more and more people are experiencing a variety of ocular symptoms related to computer use. These include eyestrain, tired eyes, irritation, redness, blurred vision, and double vision, collectively referred to as computer vision syndrome. This article describes both the characteristics and treatment modalities that are available at this time. Computer vision syndrome symptoms may be the cause of ocular (ocular-surface abnormalities or accommodative spasms) and/or extraocular (ergonomic) etiologies. However, the major contributor to computer vision syndrome symptoms by far appears to be dry eye. The visual effects of various display characteristics such as lighting, glare, display quality, refresh rates, and radiation are also discussed. Treatment requires a multidirectional approach combining ocular therapy with adjustment of the workstation. Proper lighting, anti-glare filters, ergonomic positioning of computer monitor and regular work breaks may help improve visual comfort. Lubricating eye drops and special computer glasses help relieve ocular surface-related symptoms. More work needs to be done to specifically define the processes that cause computer vision syndrome and to develop and improve effective treatments that successfully address these causes.

  10. Application of artificial intelligence to robotic vision

    SciTech Connect

    Chao, P.S.; Frick, P.A.

    1983-01-01

    A brief introduction to artificial intelligence (AI) and the general vision process is provided. Two samples of AI researchers' work toward general computer vision are given. The first is a model-based vision system while the second is based on results of studies on human vision. The current state of machine vision in industrial robotics is demonstrated using a well known vision algorithm developed at SRI International. A part of a prototype robotic assembly project with vision is sketched to show the application of some AI tools to practical work. 8 references.

  11. 77 FR 2342 - Seventeenth Meeting: RTCA Special Committee 213, Enhanced Flight Vision/Synthetic Vision Systems...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ... Federal Aviation Administration Seventeenth Meeting: RTCA Special Committee 213, Enhanced Flight Vision... Transportation (DOT). ACTION: Notice of RTCA Special Committee 213, Enhanced Flight Vision/ Synthetic Vision... meeting of RTCA Special Committee 213, Enhanced Flight Vision/Synthetic Vision Systems (EFVS/SVS). DATES...

  12. 46 CFR 10.305 - Vision requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... correctable vision to at least 20/40 in one eye and uncorrected vision of at least 20/200 in the same eye. The... correctable vision to at least 20/40 in both eyes and uncorrected vision of at least 20/200 in both eyes. A mariner who meets these requirements and who suffers loss of vision in one eye after being issued an MMC...

  13. Theory underlying the peripheral vision horizon device

    NASA Technical Reports Server (NTRS)

    Money, K. E.

    1984-01-01

    Peripheral Vision Horizon Device (PVHD) theory states that the likelihood of pilot disorientation in flight is reduced by providing an artificial horizon that provides orientation information to peripheral vision. In considering the validity of the theory, three areas are explored: the use of an artificial horizon device over some other flight instrument; the use of peripheral vision over foveal vision; and the evidence that peripheral vision is well suited to the processing of orientation information.

  14. Vision Loss in Older Adults.

    PubMed

    Pelletier, Allen L; Rojas-Roldan, Ledy; Coffin, Janis

    2016-08-01

    Vision loss affects 37 million Americans older than 50 years and one in four who are older than 80 years. The U.S. Preventive Services Task Force concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for impaired visual acuity in adults older than 65 years. However, family physicians play a critical role in identifying persons who are at risk of vision loss, counseling patients, and referring patients for disease-specific treatment. The conditions that cause most cases of vision loss in older patients are age-related macular degeneration, glaucoma, ocular complications of diabetes mellitus, and age-related cataracts. Vitamin supplements can delay the progression of age-related macular degeneration. Intravitreal injection of a vascular endothelial growth factor inhibitor can preserve vision in the neovascular form of macular degeneration. Medicated eye drops reduce intraocular pressure and can delay the progression of vision loss in patients with glaucoma, but adherence to treatment is poor. Laser trabeculoplasty also lowers intraocular pressure and preserves vision in patients with primary open-angle glaucoma, but long-term studies are needed to identify who is most likely to benefit from surgery. Tight glycemic control in adults with diabetes slows the progression of diabetic retinopathy, but must be balanced against the risks of hypoglycemia and death in older adults. Fenofibrate also slows progression of diabetic retinopathy. Panretinal photocoagulation is the mainstay of treatment for diabetic retinopathy, whereas vascular endothelial growth factor inhibitors slow vision loss resulting from diabetic macular edema. Preoperative testing before cataract surgery does not improve outcomes and is not recommended.

  15. Experimental simulation of simultaneous vision.

    PubMed

    de Gracia, Pablo; Dorronsoro, Carlos; Sánchez-González, Álvaro; Sawides, Lucie; Marcos, Susana

    2013-01-17

    To present and validate a prototype of an optical instrument that allows experimental simulation of pure bifocal vision. To evaluate the influence of different power additions on image contrast and visual acuity. The instrument provides the eye with two superimposed images, aligned and with the same magnification, but with different defocus states. Subjects looking through the instrument are able to experience pure simultaneous vision, with adjustable refractive correction and addition power. The instrument is used to investigate the impact of the amount of addition of an ideal bifocal simultaneous vision correction, both on image contrast and on visual performance. the instrument is validated through computer simulations of the letter contrast and by equivalent optical experiments with an artificial eye (camera). Visual acuity (VA) was measured in four subjects (AGE: 34.3 ± 3.4 years; spherical error: -2.1 ± 2.7 diopters [D]) for low and high contrast letters and different amounts of addition. The largest degradation in contrast and visual acuity (∼25%) occurred for additions around ±2 D, while additions of ±4 D produced lower degradation (14%). Low additions (1-2 D) result in lower VA than high additions (3-4 D). A simultaneous vision instrument is an excellent tool to simulate bifocal vision and to gain understanding of multifocal solutions for presbyopia. Simultaneous vision induces a pattern of visual performance degradation, which is well predicted by the degradation found in image quality. Neural effects, claimed to be crucial in the patients' tolerance of simultaneous vision, can be therefore compared with pure optical effects.

  16. Dim light at night exaggerates weight gain and inflammation associated with a high-fat diet in male mice.

    PubMed

    Fonken, Laura K; Lieberman, Rebecca A; Weil, Zachary M; Nelson, Randy J

    2013-10-01

    Elevated nighttime light exposure is associated with symptoms of metabolic syndrome. In industrialized societies, high-fat diet (HFD) and exposure to light at night (LAN) often cooccur and may contribute to the increasing obesity epidemic. Thus, we hypothesized that dim LAN (dLAN) would provoke additional and sustained body mass gain in mice on a HFD. Male mice were housed in either a standard light/dark cycle or dLAN and fed either chow or HFD. Exposure to dLAN and HFD increase weight gain, reduce glucose tolerance, and alter insulin secretion as compared with light/dark cycle and chow, respectively. The effects of dLAN and HFD appear additive, because mice exposed to dLAN that were fed HFD display the greatest increases in body mass. Exposure to both dLAN and HFD also change the timing of food intake and increase TNFα and MAC1 gene expression in white adipose tissue after 4 experimental weeks. Changes in MAC1 gene expression occur more rapidly due to HFD as compared with dLAN; after 5 days of experimental conditions, mice fed HFD already increase MAC1 gene expression in white adipose tissue. HFD also elevates microglia activation in the arcuate nucleus of the hypothalamus and hypothalamic TNFα, IL-6, and Ikbkb gene expression. Microglia activation is increased by dLAN, but only among chow-fed mice and dLAN does not affect inflammatory gene expression. These results suggest that dLAN exaggerates weight gain and peripheral inflammation associated with HFD.

  17. Depressive-like behavior is elevated among offspring of parents exposed to dim light at night prior to mating.

    PubMed

    Cissé, Yasmine M; Russart, Kathryn L G; Nelson, Randy J

    2017-09-01

    Rates of major depressive disorder (MDD) have steadily increased over the past 50 years. Many factors have been implicated in the etiology of depressive disorders and environmental influences are being increasingly recognized. The increase in depression rates has coincided with increased artificial nighttime lighting. Exposure to light at night (LAN) has been associated with increased depressive-like behavior in rodents and decreased mood in humans. However, relatively little is known on the multigenerational effects of dLAN on affect. In this study, we exposed adult male and female Siberian hamsters (Phodopus sungorus) to either DARK (0lx) or dim LAN (5lx) for 9 weeks, then paired animals in a full factorial design; all animals were thereafter housed in dark nights. Offspring were gestated and reared in dark nights, then tested in adulthood for depressive-like behaviors and hippocampal expression of glucocorticoid (GR) and melatonin (MT1) receptor expression. Maternal exposure to dLAN decreased sucrose preference, time to first float bout in the Porsolt swim test, and GR expression in the hippocampus. Paternal exposure to dLAN increased time spent floating, and increased hippocampal GR expression. Overall, our results suggest that chronic exposure of parents to light at night has multigenerational effects on offspring depressive-like behavior. If these results pertain to humans, then our data suggest that LAN may contribute to the rapidly rising rates of major depressive disorder in industrialized and developing countries. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Pulsing blue light through closed eyelids: effects on acute melatonin suppression and phase shifting of dim light melatonin onset.

    PubMed

    Figueiro, Mariana G; Plitnick, Barbara; Rea, Mark S

    2014-01-01

    Circadian rhythm disturbances parallel the increased prevalence of sleep disorders in older adults. Light therapies that specifically target regulation of the circadian system in principle could be used to treat sleep disorders in this population. Current recommendations for light treatment require the patients to sit in front of a bright light box for at least 1 hour daily, perhaps limiting their willingness to comply. Light applied through closed eyelids during sleep might not only be efficacious for changing circadian phase but also lead to better compliance because patients would receive light treatment while sleeping. Reported here are the results of two studies investigating the impact of a train of 480 nm (blue) light pulses presented to the retina through closed eyelids on melatonin suppression (laboratory study) and on delaying circadian phase (field study). Both studies employed a sleep mask that provided narrowband blue light pulses of 2-second duration every 30 seconds from arrays of light-emitting diodes. The results of the laboratory study demonstrated that the blue light pulses significantly suppressed melatonin by an amount similar to that previously shown in the same protocol at half the frequency (ie, one 2-second pulse every minute for 1 hour). The results of the field study demonstrated that blue light pulses given early in the sleep episode significantly delayed circadian phase in older adults; these results are the first to demonstrate the efficacy and practicality of light treatment by a sleep mask aimed at adjusting circadian phase in a home setting.

  19. Pulsing blue light through closed eyelids: effects on acute melatonin suppression and phase shifting of dim light melatonin onset

    PubMed Central

    Figueiro, Mariana G; Plitnick, Barbara; Rea, Mark S

    2014-01-01

    Circadian rhythm disturbances parallel the increased prevalence of sleep disorders in older adults. Light therapies that specifically target regulation of the circadian system in principle could be used to treat sleep disorders in this population. Current recommendations for light treatment require the patients to sit in front of a bright light box for at least 1 hour daily, perhaps limiting their willingness to comply. Light applied through closed eyelids during sleep might not only be efficacious for changing circadian phase but also lead to better compliance because patients would receive light treatment while sleeping. Reported here are the results of two studies investigating the impact of a train of 480 nm (blue) light pulses presented to the retina through closed eyelids on melatonin suppression (laboratory study) and on delaying circadian phase (field study). Both studies employed a sleep mask that provided narrowband blue light pulses of 2-second duration every 30 seconds from arrays of light-emitting diodes. The results of the laboratory study demonstrated that the blue light pulses significantly suppressed melatonin by an amount similar to that previously shown in the same protocol at half the frequency (ie, one 2-second pulse every minute for 1 hour). The results of the field study demonstrated that blue light pulses given early in the sleep episode significantly delayed circadian phase in older adults; these results are the first to demonstrate the efficacy and practicality of light treatment by a sleep mask aimed at adjusting circadian phase in a home setting. PMID:25506253

  20. Reliable vision-guided grasping

    NASA Technical Reports Server (NTRS)

    Nicewarner, Keith E.; Kelley, Robert B.

    1992-01-01

    Automated assembly of truss structures in space requires vision-guided servoing for grasping a strut when its position and orientation are uncertain. This paper presents a methodology for efficient and robust vision-guided robot grasping alignment. The vision-guided grasping problem is related to vision-guided 'docking' problems. It differs from other hand-in-eye visual servoing problems, such as tracking, in that the distance from the target is a relevant servo parameter. The methodology described in this paper is hierarchy of levels in which the vision/robot interface is decreasingly 'intelligent,' and increasingly fast. Speed is achieved primarily by information reduction. This reduction exploits the use of region-of-interest windows in the image plane and feature motion prediction. These reductions invariably require stringent assumptions about the image. Therefore, at a higher level, these assumptions are verified using slower, more reliable methods. This hierarchy provides for robust error recovery in that when a lower-level routine fails, the next-higher routine will be called and so on. A working system is described which visually aligns a robot to grasp a cylindrical strut. The system uses a single camera mounted on the end effector of a robot and requires only crude calibration parameters. The grasping procedure is fast and reliable, with a multi-level error recovery system.

  1. The Medawar Lecture 2001 Knowledge for vision: vision for knowledge

    PubMed Central

    Gregory, Richard L

    2005-01-01

    An evolutionary development of perception is suggested—from passive reception to active perception to explicit conception—earlier stages being largely retained and incorporated in later species. A key is innate and then individually learned knowledge, giving meaning to sensory signals. Inappropriate or misapplied knowledge produces rich cognitive phenomena of illusions, revealing normally hidden processes of vision, tentatively classified here in a ‘peeriodic table’. Phenomena of physiology are distinguished from phenomena of general rules and specific object knowledge. It is concluded that vision uses implicit knowledge, and provides knowledge for intelligent behaviour and for explicit conceptual understanding including science. PMID:16147519

  2. Proteins.

    ERIC Educational Resources Information Center

    Doolittle, Russell F.

    1985-01-01

    Examines proteins which give rise to structure and, by virtue of selective binding to other molecules, make genes. Binding sites, amino acids, protein evolution, and molecular paleontology are discussed. Work with encoding segments of deoxyribonucleic acid (exons) and noncoding stretches (introns) provides new information for hypotheses. (DH)

  3. Proteins.

    ERIC Educational Resources Information Center

    Doolittle, Russell F.

    1985-01-01

    Examines proteins which give rise to structure and, by virtue of selective binding to other molecules, make genes. Binding sites, amino acids, protein evolution, and molecular paleontology are discussed. Work with encoding segments of deoxyribonucleic acid (exons) and noncoding stretches (introns) provides new information for hypotheses. (DH)

  4. Protein

    USDA-ARS?s Scientific Manuscript database

    Proteins are the major structural and functional components of all cells in the body. They are macromolecules that comprise 1 or more chains of amino acids that vary in their sequence and length and are folded into specific 3-dimensional structures. The sizes and conformations of proteins, therefor...

  5. Night vision device technology development

    SciTech Connect

    Funsten, H.; Nordholt, J.; Suszcynsky, D.

    1996-09-01

    This is the final report of a one-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). This project sought to develop microchannel plate (MCP) technologies for enhancement of night vision device (NVD) capabilities. First, segmented microchannel plates with independent gain control to minimize loss of low level light images in the presence of a bright light source (e.g., battlefield lasers, flares, and headlights) need to be developed. This enables, for example, enhanced vision capabilities during night operations in, for example, a city environment and continuous capability of aviators to see the horizon, nearground obstructions, and ground targets. Furthermore, curved microchannel plate technology to increase the field of view of NVDs while minimizing optical aberrations needs to be developed and applied. This development would significantly enhance peripheral vision capabilities of aviators and result in easier adaptation of the human eye to NVDs.

  6. Using rats for vision research.

    PubMed

    Reinagel, P

    2015-06-18

    A wide variety of species are used for the study of visual neuroscience. This is beneficial because fundamental mechanisms and theoretical principles of vision are likely to be highly conserved, while different species exhibit different visual capacities and present different technical advantages for experiments. Eight years ago my laboratory adopted the hooded rat as our primary preparation for vision research. To some this may be surprising, as nocturnal rodents have often been presumed to have poor vision and weak visual behavior. This commentary will provide my personal perspective on how I came to work with rats; discuss an example research project for which rats have been advantageous; and comment on the opportunities and challenges of the preparation.

  7. Binocular vision and refractive surgery.

    PubMed

    Finlay, Alison L

    2007-05-01

    Binocular status can have an effect on the outcome of refractive surgery. Some accommodative deviations and anisometropia can be managed effectively. Fully accommodative esotropia has been successfully treated in young patients but the outcome can be less predictable in older patients. High anisometropes are usually unaffected by the change in aniseikonia following refractive surgery but there are exceptions. Failure to recognise and appropriately classify a binocular vision anomaly pre-surgically can result in symptoms that are difficult to manage post-operatively. Refractive surgery producing a binocular vision anomaly where there was none pre-operatively is less common. I present a review of the literature discussing the relationship between binocular vision anomalies and refractive surgery, illustrating the findings with published reports of successful and unsuccessful binocular postoperative outcomes. I argue that predicting the binocular outcome should be considered pre-operatively for every refractive surgery patient.

  8. The unsolved mystery of vision.

    PubMed

    Masland, Richard H; Martin, Paul R

    2007-08-07

    Vision looms large in neuroscience--it is the subject of a gigantic literature and four Nobel prizes--but there is a growing realization that there are problems with the textbook explanation of how mammalian vision works. Here we will summarize the evidence behind this disquiet. In effect, we shall present a portrait of a field that is 'stuck'. Our initial focus, because it is our area of expertise, is on evidence that the early steps of mammalian vision are more diverse and more interesting than is usually imagined, so that our understanding of the later stages is in trouble right from the start. But we will also summarize problems, raised by others, with the later stages themselves.

  9. Motion vision for mobile robots

    NASA Astrophysics Data System (ADS)

    Herrb, Matthieu

    The problem of using computer vision in mobile robots is dealt with. The datacube specialized cards and a parallel machine using a transputer network are studied. The tracking and localization of a three dimensional object in a sequence of images is examined, using first order prediction of the motion in the image plane and verification by a maximal clique search in the graph of mutually compatible matchings. A dynamic environment modeling module, using numerical fusion between trinocular stereovision and tracking of stereo matched primitives is presented. The integration of this perception system in the control architecture of a mobile robot is examined to achieve various functions, such as vision servo motion and environment modeling. The functional units implementing vision tasks and the data exchanged with other units are outlined. Experiments realized with the mobile robot Hilare 1.5 allowed the proposed algorithms and concepts to be validated.

  10. Preschool vision screening.

    PubMed

    Snowdon, S K; Stewart-Brown, S L

    1997-01-01

    To undertake a systematic review of the effectiveness of preschool vision screening. To provide evidence on which decisions about the future provision of this service can be made. To indicate areas for further research. The Centre for Reviews and Dissemination guidelines for systematic reviews were used. The research questions were formulated using the Wilson and Jungner criteria for evaluating screening programmes. They concerned prevalence, natural history, disability, treatment and screening in relation to three target conditions: amblyopia, refractive errors and squints which are not cosmetically obvious. Studies were considered for inclusion according to pre-determined criteria for the age group studied, the outcomes measured and the study design. The following types of study design were considered: cross-sectional studies of prevalence, cohort studies of natural history, any type of study (e.g., cross-sectional surveys, case-series, qualitative studies) of disability attributable to a target condition, controlled trials, observational studies and audits of screening programmes, and prospective controlled trials of treatment. The following electronic databases were searched: Biological Abstracts, CINAHL, Embase, ERIC, IAC Health Periodicals, IAPV, Medline, Psychlit, Science Citation Index, System for Information on Grey Literature in Europe, DHSS-Data, Faculty of Public Health Medicine Database of Dissertations, Index of Scientific and Technical Proceedings, Dissertation Abstracts, Index of Theses, NHS Research Register, Public Health Information Sharing Database. A limited amount of handsearching was undertaken. Reference lists were scanned to identify other relevant studies, and requests for unpublished data were made to people working in the field. Data was extracted by the first author and then checked by the second. Quantitative analysis was undertaken where possible. Qualitative analysis was performed where studies were too heterogeneous for the data to

  11. Computer vision in cell biology.

    PubMed

    Danuser, Gaudenz

    2011-11-23

    Computer vision refers to the theory and implementation of artificial systems that extract information from images to understand their content. Although computers are widely used by cell biologists for visualization and measurement, interpretation of image content, i.e., the selection of events worth observing and the definition of what they mean in terms of cellular mechanisms, is mostly left to human intuition. This Essay attempts to outline roles computer vision may play and should play in image-based studies of cellular life. Copyright © 2011 Elsevier Inc. All rights reserved.

  12. Computer vision in nuclear medicine

    NASA Astrophysics Data System (ADS)

    Sommer, Gerald

    1990-11-01

    Computervision is used to overcome the mismatch between user models and implementation models of software systems for image analysis in nuclear medicine. Computer vision in nuclear medicine results in an active support of the user by the system. This is reached by modeling of imaging equipment and schedules scenes of interest and the process of visual image interpretation. Computer vision is demonstrated especially in the low level and medium level range. Special highlights are given for the estimation of image quality an uniform approach to enhancement and restoration of images and analysis of shape and dynamics of patterns. 1.

  13. VISIONS - Vista Star Formation Atlas

    NASA Astrophysics Data System (ADS)

    Meingast, Stefan; Alves, J.; Boui, H.; Ascenso, J.

    2017-06-01

    In this talk I will present the new ESO public survey VISIONS. Starting in early 2017 we will use the ESO VISTA survey telescope in a 550 h long programme to map the largest molecular cloud complexes within 500 pc in a multi-epoch program. The survey is optimized for measuring the proper motions of young stellar objects invisible to Gaia and mapping the cloud-structure with extinction. VISIONS will address a series of ISM topics ranging from the connection of dense cores to YSOs and the dynamical evolution of embedded clusters to variations in the reddening law on both small and large scales.

  14. Precise calibration of binocular vision system used for vision measurement.

    PubMed

    Cui, Yi; Zhou, Fuqiang; Wang, Yexin; Liu, Liu; Gao, He

    2014-04-21

    Binocular vision calibration is of great importance in 3D machine vision measurement. With respect to binocular vision calibration, the nonlinear optimization technique is a crucial step to improve the accuracy. The existing optimization methods mostly aim at minimizing the sum of reprojection errors for two cameras based on respective 2D image pixels coordinate. However, the subsequent measurement process is conducted in 3D coordinate system which is not consistent with the optimization coordinate system. Moreover, the error criterion with respect to optimization and measurement is different. The equal pixel distance error in 2D image plane leads to diverse 3D metric distance error at different position before the camera. To address these issues, we propose a precise calibration method for binocular vision system which is devoted to minimizing the metric distance error between the reconstructed point through optimal triangulation and the ground truth in 3D measurement coordinate system. In addition, the inherent epipolar constraint and constant distance constraint are combined to enhance the optimization process. To evaluate the performance of the proposed method, both simulative and real experiments have been carried out and the results show that the proposed method is reliable and efficient to improve measurement accuracy compared with conventional method.

  15. Global Perspectives on Teaching Literature: Shared Visions and Distinctive Visions.

    ERIC Educational Resources Information Center

    Lott, Sandra Ward, Ed.; And Others

    This book is a collection of essays designed for high school and college teachers who want to introduce non-Western and other non-canonical texts into their traditional literature courses. The essays in the book explore the kinds of visions encountered when teachers cluster Western texts with those outside the dominant Western tradition. Papers in…

  16. Visions and Re-Visions of Charles Joseph Minard.

    ERIC Educational Resources Information Center

    Friendly, Michael

    2002-01-01

    Describes the contributions of Charles Joseph Minard to statistical graphics, noting the time course of his work and providing background on his famous effort, the flow-map depiction of Napoleon's march on Moscow. Explores some modern re-visions of this famous graphic from an information visualization perspective. (SLD)

  17. Visions and Re-Visions of Charles Joseph Minard.

    ERIC Educational Resources Information Center

    Friendly, Michael

    2002-01-01

    Describes the contributions of Charles Joseph Minard to statistical graphics, noting the time course of his work and providing background on his famous effort, the flow-map depiction of Napoleon's march on Moscow. Explores some modern re-visions of this famous graphic from an information visualization perspective. (SLD)

  18. VisionCite: A Vision Science-Related Database.

    PubMed

    Lamson, Karen S; Hinton, Elizabeth G

    2017-01-01

    VisionCite is a database dedicated to the visual sciences. This paid subscription database provides bibliographic information for optometry and ophthalmology-related resources and is maintained by the Illinois College of Optometry (ICO) Library. A sample search is provided, highlighting different features of the newly redesigned database.

  19. Daylight vision repair by cell transplantation.

    PubMed

    Santos-Ferreira, Tiago; Postel, Kai; Stutzki, Henrike; Kurth, Thomas; Zeck, Günther; Ader, Marius

    2015-01-01

    Human daylight vision depends on cone photoreceptors and their degeneration results in visual impairment and blindness as observed in several eye diseases including age-related macular degeneration, cone-rod dystrophies, or late stage retinitis pigmentosa, with no cure available. Preclinical cell replacement approaches in mouse retina have been focusing on rod dystrophies, due to the availability of sufficient donor material from the rod-dominated mouse retina, leaving the development of treatment options for cone degenerations not well studied. Thus, an abundant and traceable source for donor cone-like photoreceptors was generated by crossing neural retina leucine zipper-deficient (Nrl(-/-) ) mice with an ubiquitous green fluorescent protein (GFP) reporter line resulting in double transgenic tg(Nrl(-/-); aGFP) mice. In Nrl(-/-) retinas, all rods are converted into cone-like photoreceptors that express CD73 allowing their enrichment by CD73-based magnetic activated cell sorting prior transplantation into the subretinal space of adult wild-type, cone-only (Nrl(-/-)), or cone photoreceptor function loss 1 (Cpfl1) mice. Donor cells correctly integrated into host retinas, acquired mature photoreceptor morphology, expressed cone-specific markers, and survived for up to 6 months, with significantly increased integration rates in the cone-only Nrl(-/-) retina. Individual retinal ganglion cell recordings demonstrated the restoration of photopic responses in cone degeneration mice following transplantation suggesting, for the first time, the feasibility of daylight vision repair by cell replacement in the adult mammalian retina. © 2014 AlphaMed Press.

  20. Quality Control by Artificial Vision

    SciTech Connect

    Lam, Edmond Y.; Gleason, Shaun Scott; Niel, Kurt S.

    2010-01-01

    Computational technology has fundamentally changed many aspects of our lives. One clear evidence is the development of artificial-vision systems, which have effectively automated many manual tasks ranging from quality inspection to quantitative assessment. In many cases, these machine-vision systems are even preferred over manual ones due to their repeatability and high precision. Such advantages come from significant research efforts in advancing sensor technology, illumination, computational hardware, and image-processing algorithms. Similar to the Special Section on Quality Control by Artificial Vision published two years ago in Volume 17, Issue 3 of the Journal of Electronic Imaging, the present one invited papers relevant to fundamental technology improvements to foster quality control by artificial vision, and fine-tuned the technology for specific applications. We aim to balance both theoretical and applied work pertinent to this special section theme. Consequently, we have seven high-quality papers resulting from the stringent peer-reviewing process in place at the Journal of Electronic Imaging. Some of the papers contain extended treatment of the authors work presented at the SPIE Image Processing: Machine Vision Applications conference and the International Conference on Quality Control by Artificial Vision. On the broad application side, Liu et al. propose an unsupervised texture image segmentation scheme. Using a multilayer data condensation spectral clustering algorithm together with wavelet transform, they demonstrate the effectiveness of their approach on both texture and synthetic aperture radar images. A problem related to image segmentation is image extraction. For this, O'Leary et al. investigate the theory of polynomial moments and show how these moments can be compared to classical filters. They also show how to use the discrete polynomial-basis functions for the extraction of 3-D embossed digits, demonstrating superiority over Fourier

  1. Protein

    MedlinePlus

    ... Search for: Harvard T.H. Chan School of Public Health Email People Departments Calendar Careers Give my.harvard ... Nutrition Source Harvard T.H. Chan School of Public Health > The Nutrition Source > What Should I Eat? > Protein ...

  2. Availability of vision and tactile gating: vision enhances tactile sensitivity.

    PubMed

    Colino, Francisco L; Lee, Ji-Hang; Binsted, Gordon

    2017-01-01

    A multitude of events bombard our sensory systems at every moment of our lives. Thus, it is important for the sensory and motor cortices to gate unimportant events. Tactile suppression is a well-known phenomenon defined as a reduced ability to detect tactile events on the skin before and during movement. Previous experiments (Buckingham et al. in Exp Brain Res 201(3):411-419, 2010; Colino et al. in Physiol Rep 2(3):e00267, 2014) found detection rates decrease just prior to and during finger abduction and decrease according to the proximity of the moving effector. However, what effect does vision have on tactile gating? There is ample evidence (see Serino and Haggard in Neurosci Biobehav Rev 34:224-236, 2010) observing increased tactile acuity when participants see their limbs. The present study examined how tactile detection changes in response to visual condition (vision/no vision). Ten human participants used their right hand to reach and grasp a cylinder. Tactors were attached to the index finger and the forearm of both the right and left arm and vibrated at various epochs relative to a "go" tone. Results replicate previous findings from our laboratory (Colino et al. in Physiol Rep 2(3):e00267, 2014). Also, tactile acuity decreased when participants did not have vision. These results indicate that the vision affects the somatosensation via inputs from parietal areas (Konen and Haggard in Cereb Cortex 24(2):501-507, 2014) but does so in a reach-to-grasp context.

  3. Circadian oscillation of nitrate reductase activity in Gonyaulax polyedra is due to changes in cellular protein levels.

    PubMed Central

    Ramalho, C B; Hastings, J W; Colepicolo, P

    1995-01-01

    A circadian rhythm in the activity of nitrate reductase (NR; EC 1.6.6.1) isolated from the marine dinoflagellate Gonyaulax polyedra is shown to be attributable to the daily synthesis and destruction of the protein. The enzyme was purified in three steps: gel filtration on S-300 Sephacryl, an Affigel-Blue column, and a diethylaminoethyl ion-exchange column. Undenatured protein shows a molecular mass of about 310 kD; based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, the enzyme appears to be composed of six possibly identical subunits. The amino acid composition of the G. polyedra NR is very similar to that reported for the NR of barley leaves, Chlorella vulgaris, and Ankistrodesmus braunii. The experiments reported indicate that the cellular expression of NR is under circadian control. In extracts of cells grown under either constant dim light or a light-dark cycle, the activity of NR exhibits a daily rhythm, peaking at midday phase, as does photosynthesis. Staining with affinity-purified polyclonal antibodies, raised in rabbits against purified NR, shows that the amount of protein changes by a factor of about 10, with the maximum occurring in midday phase. PMID:7870813

  4. Visions of Vision: An Exploratory Study of the Role College and University Presidents Play in Developing Institutional Vision

    ERIC Educational Resources Information Center

    McWade, Jessica C.

    2014-01-01

    This qualitative research explores how college and university presidents engage in the process of developing formal institutional vision. The inquiry identifies roles presidents play in vision development, which is often undertaken as part of strategic-planning initiatives. Two constructs of leadership and institutional vision are used to examine…

  5. Visions of Vision: An Exploratory Study of the Role College and University Presidents Play in Developing Institutional Vision

    ERIC Educational Resources Information Center

    McWade, Jessica C.

    2014-01-01

    This qualitative research explores how college and university presidents engage in the process of developing formal institutional vision. The inquiry identifies roles presidents play in vision development, which is often undertaken as part of strategic-planning initiatives. Two constructs of leadership and institutional vision are used to examine…

  6. Old and new results about single-photon sensitivity in human vision.

    PubMed

    Nelson, Philip C

    2016-04-04

    It is sometimes said that 'our eyes can see single photons'. This article begins by finding a more precise version of that claim and reviewing evidence gathered for it up to around 1985 in two distinct realms, those of human psychophysics and single-cell physiology. Finding a single framework that accommodates both kinds of result is then a nontrivial challenge, and one that sets severe quantitative constraints on any model of dim-light visual processing. This article presents one such model and compares it to a recent experiment.

  7. A Clear Vision for Equity and Opportunity.

    ERIC Educational Resources Information Center

    Gould, Marge Christensen; Gould, Herman

    2003-01-01

    Describes undetected and uncorrected vision problems for children in poverty associated with juvenile delinquency and poor academic performance. Discusses success of a project offering vision screening and free glasses for at-risk students in Tucson, Arizona. (PKP)

  8. Vision Problems Can Harm Kids' Development, Grades

    MedlinePlus

    ... for Children's Vision and Eye Health at Prevent Blindness. "The good news is that many vision problems ... early," Hugh Parry, president and CEO of Prevent Blindness, said in a news release from the organization. ...

  9. Vision Problems: How Teachers Can Help.

    ERIC Educational Resources Information Center

    Desrochers, Joyce

    1999-01-01

    Describes common vision problems in young children such as myopia, strabismus, and amblyopia. Presents suggestions for helping children with vision problems in the early childhood classroom and in outdoor activities. Lists related resources and children's books. (KB)

  10. A Clear Vision for Equity and Opportunity.

    ERIC Educational Resources Information Center

    Gould, Marge Christensen; Gould, Herman

    2003-01-01

    Describes undetected and uncorrected vision problems for children in poverty associated with juvenile delinquency and poor academic performance. Discusses success of a project offering vision screening and free glasses for at-risk students in Tucson, Arizona. (PKP)

  11. Evolution of body size, vision, and biodiversity of coral-associated organisms: evidence from fossil crustaceans in cold-water coral and tropical coral ecosystems.

    PubMed

    Klompmaker, Adiël A; Jakobsen, Sten L; Lauridsen, Bodil W

    2016-06-16

    Modern cold-water coral and tropical coral environments harbor a highly diverse and ecologically important macrofauna of crustaceans that face elevated extinction risks due to reef decline. The effect of environmental conditions acting on decapod crustaceans comparing these two habitats is poorly understood today and in deep time. Here, we compare the biodiversity, eye socket height as a proxy for eye size, and body size of decapods in fossil cold-water and tropical reefs that formed prior to human disturbance. We show that decapod biodiversity is higher in fossil tropical reefs from The Netherlands, Italy, and Spain compared to that of the exceptionally well-preserved Paleocene (Danian) cold-water reef/mound ecosystem from Faxe (Denmark), where decapod diversity is highest in a more heterogeneous, mixed bryozoan-coral habitat instead of in coral and bryozoan-dominated facies. The relatively low diversity at Faxe was not influenced substantially by the preceding Cretaceous/Paleogene extinction event that is not apparent in the standing diversity of decapods in our analyses, or by sampling, preservation, and/or a latitudinal diversity gradient. Instead, the lower availability of food and fewer hiding places for decapods may explain this low diversity. Furthermore, decapods from Faxe are larger than those from tropical waters for half of the comparisons, which may be caused by a lower number of predators, the delayed maturity, and the increased life span of crustaceans in deeper, colder waters. Finally, deep-water specimens of the benthic crab Caloxanthus from Faxe exhibit a larger eye socket size compared to congeneric specimens from tropical reefs, suggesting that dim light conditions favored the evolution of relatively large eyes. The results suggest a strong habitat control on the biodiversity of crustaceans in coral-associated environments and that the diversity difference between deep, cold-water reefs and tropical reefs evolved at least ~63 million years ago

  12. The Physics of Colour Vision.

    ERIC Educational Resources Information Center

    Goldman, Martin

    1985-01-01

    An elementary physical model of cone receptor cells is explained and applied to complexities of human color vision. One-, two-, and three-receptor systems are considered, with the later shown to be the best model for the human eye. Color blindness is also discussed. (DH)

  13. Standards for vision science libraries

    PubMed Central

    2000-01-01

    The minimum levels of staffing, services, budget, and technology that should be provided by a library specializing in vision science are presented. The scope and coverage of the collection is described as well. These standards may be used by institutions establishing libraries or by accrediting bodies reviewing existing libraries. PMID:10928708

  14. Polarization Imaging and Insect Vision

    ERIC Educational Resources Information Center

    Green, Adam S.; Ohmann, Paul R.; Leininger, Nick E.; Kavanaugh, James A.

    2010-01-01

    For several years we have included discussions about insect vision in the optics units of our introductory physics courses. This topic is a natural extension of demonstrations involving Brewster's reflection and Rayleigh scattering of polarized light because many insects heavily rely on optical polarization for navigation and communication.…

  15. Enhanced vision meets pilot assistance

    NASA Astrophysics Data System (ADS)

    Hecker, Peter; Doehler, Hans-Ullrich; Suikat, Reiner

    1999-07-01

    As presented in previous contributions within SPIE's Enhanced and Synthetic Vision Conferences, DLR's Institute of Flight Guidance is involved in the design, development and testing of enhanced vision systems for flight guidance applications. The combination of forward looking imaging sensors (such as DaimlerChrysler's HiVision millimeter wave radar), terrain data stored in on-board databases plus information transmitted from ground or on-board other aircraft via data link is used to give the air crew an improved situational awareness. This helps pilots to handle critical tasks, such as landing approaches and taxiing especially under adverse weather conditions. The research and development of this system was mostly funded by a national research program from mid of 1996 to mid of 1999. On one hand this paper will give a general overview about the project and the lessons learned. Results of flight tests carried out recently will be shown as well as brief looks into evaluation tests on-board an Airbus A-340 full flight simulator performed mid of 1998 at the Flight Simulation Center Berlin. On the other hand an outlook will be presented, which shows enhanced vision systems as a major player in the theater of pilot assistance systems as they are under development at DLR's Institute of Flight Guidance in close cooperation with the University of the Federal Armed Forces in Munich, Germany.

  16. Institutionalizing a Vision for Diversity.

    ERIC Educational Resources Information Center

    Miserandino, Anthony

    1998-01-01

    Institutionalizing a vision for diversity should include (1) commitment to serving students' perceived needs; (2) seeing through the lens of others' experiences; (3) moral leadership from teachers; (4) a sufficient pool of support and goodwill; and (5) focus on students first. (SK)

  17. The Common Vision. Reviews: Books.

    ERIC Educational Resources Information Center

    Chattin-McNichols, John

    1998-01-01

    Reviews Marshak's book describing the work of educators Maria Montessori, Rudolf Steiner, Aurobindo Ghose, and Inayat Khan. Maintains that the book gives clear, concise information on each educator and presents a common vision for children and their education; also maintains that it gives theoretical and practical information and discusses…

  18. The Physics of Colour Vision.

    ERIC Educational Resources Information Center

    Goldman, Martin

    1985-01-01

    An elementary physical model of cone receptor cells is explained and applied to complexities of human color vision. One-, two-, and three-receptor systems are considered, with the later shown to be the best model for the human eye. Color blindness is also discussed. (DH)

  19. Central Vision in the Newborn.

    ERIC Educational Resources Information Center

    Lewis, Terri L.; Maurer, Daphne

    1980-01-01

    Tests newborns' ability to detect a dot with central vision and compares both the proportion of time the infants fixated centrally and the duration of each central fixation. Subjects were 46 newborns ranging in age from 1 to 7 days. (MP)

  20. Assessing Functional Vision Using Microcomputers.

    ERIC Educational Resources Information Center

    Spencer, Simon; Ross, Malcolm

    1989-01-01

    The paper describes a software system which uses microcomputers to aid in the assessment of functional vision in visually impaired students. The software also aims to be visually stimulating and to develop hand-eye coordination, visual memory, and cognitive abilities. (DB)

  1. Vision Development in the Classroom.

    ERIC Educational Resources Information Center

    Busby, Robert A.

    1985-01-01

    A vision evaluation and enhancement program was used with 59 elementary multihandicapped students to prevent future problems in educational and social development. Ss with eye-movement difficulties, eye-hand coordination problems and/or difficulty in visual perception skills improved after program participation. (CL)

  2. Unshackled by Visions and Values.

    ERIC Educational Resources Information Center

    Brokenleg, Martin

    1996-01-01

    Uses a case study to demonstrate the effects of cultural conflict, alienation, anomie, and contemporary urban society on the lives of troubled Native American youth. Shows that by teaching traditional Native American values, such as visions of hope and independence, society can help these youth enjoy a promising future. (RJM)

  3. Vision Screening of the Aged

    ERIC Educational Resources Information Center

    Hanson, Howard H.

    1971-01-01

    A statewide project in South Dakota has screened the vision of 2,578 elderly persons in 90 nursing homes, finding 13 percent legally blind and referring 32 percent for services either from agencies for the blind or from physicians or optometrists. (KW)

  4. Unshackled by Visions and Values.

    ERIC Educational Resources Information Center

    Brokenleg, Martin

    1996-01-01

    Uses a case study to demonstrate the effects of cultural conflict, alienation, anomie, and contemporary urban society on the lives of troubled Native American youth. Shows that by teaching traditional Native American values, such as visions of hope and independence, society can help these youth enjoy a promising future. (RJM)

  5. Vision Research for Flight Simulation.

    DTIC Science & Technology

    1982-07-01

    THOMAS M. LONGRIDGE Contract Monitor MILTON E. WOOD. Technical Director Operations Training Division RONALD W’. TERRY, Coloneli USAF Commander I! I V...13:30 Hardware Developments B. Erikson 13:30 - 14:00 Future Directions G. Buckland 14:00 - 17:00 Committee on Vision: 14:00-14:15 Introduction W

  6. Vision quality of elderly Oklahomans.

    PubMed

    Imes, C B; Peck, C

    1993-06-01

    The purposes of this study are to determine if age related visual changes are affecting the ability of older adults to perform everyday tasks, to identify histories of eye diseases/eye surgeries, and to document eye care practices. Our sample was obtained from the Third Age Life Center at Baptist Medical Center in Oklahoma City. The survey was mailed to 14,856 members; 848 (6%) surveys were returned. Over 84% of the respondents have never been diagnosed with dry eye syndrome, glaucoma, macular degeneration, or diabetic retinopathy. Sixty percent rated their health and vision quality as good. Females expressed more vision problems than males. Advanced age (75 years or older) did increase likelihood of experiencing eye diseases and vision difficulties. The majority of respondents in this study appear to be experiencing healthy vision with minimal age-related changes and have not been diagnosed with the eye diseases characteristic of this age group. Evidence of regular eye examinations was reported, with 33% of the respondents reporting having eye exams once a year and 33% twice a year.

  7. Frame Rate and Human Vision

    NASA Technical Reports Server (NTRS)

    Watson, Andrew B.

    2012-01-01

    To enhance the quality of the theatre experience, the film industry is interested in achieving higher frame rates for capture and display. In this talk I will describe the basic spatio-temporal sensitivities of human vision, and how they respond to the time sequence of static images that is fundamental to cinematic presentation.

  8. Will Retinal Implants Restore Vision?

    NASA Astrophysics Data System (ADS)

    Zrenner, Eberhart

    2002-02-01

    A number of research groups are developing electrical implants that can be attached directly to the retina in an attempt to restore vision to patients suffering from retinal degeneration. However, despite promising results in animal experiments, there are still several major obstacles to overcome before retinal prostheses can be used clinically.

  9. Polarization Imaging and Insect Vision

    ERIC Educational Resources Information Center

    Green, Adam S.; Ohmann, Paul R.; Leininger, Nick E.; Kavanaugh, James A.

    2010-01-01

    For several years we have included discussions about insect vision in the optics units of our introductory physics courses. This topic is a natural extension of demonstrations involving Brewster's reflection and Rayleigh scattering of polarized light because many insects heavily rely on optical polarization for navigation and communication.…

  10. Neural architectures for stereo vision.

    PubMed

    Parker, Andrew J; Smith, Jackson E T; Krug, Kristine

    2016-06-19

    Stereoscopic vision delivers a sense of depth based on binocular information but additionally acts as a mechanism for achieving correspondence between patterns arriving at the left and right eyes. We analyse quantitatively the cortical architecture for stereoscopic vision in two areas of macaque visual cortex. For primary visual cortex V1, the result is consistent with a module that is isotropic in cortical space with a diameter of at least 3 mm in surface extent. This implies that the module for stereo is larger than the repeat distance between ocular dominance columns in V1. By contrast, in the extrastriate cortical area V5/MT, which has a specialized architecture for stereo depth, the module for representation of stereo is about 1 mm in surface extent, so the representation of stereo in V5/MT is more compressed than V1 in terms of neural wiring of the neocortex. The surface extent estimated for stereo in V5/MT is consistent with measurements of its specialized domains for binocular disparity. Within V1, we suggest that long-range horizontal, anatomical connections form functional modules that serve both binocular and monocular pattern recognition: this common function may explain the distortion and disruption of monocular pattern vision observed in amblyopia.This article is part of the themed issue 'Vision in our three-dimensional world'. © 2016 The Authors.

  11. Neural architectures for stereo vision

    PubMed Central

    2016-01-01

    Stereoscopic vision delivers a sense of depth based on binocular information but additionally acts as a mechanism for achieving correspondence between patterns arriving at the left and right eyes. We analyse quantitatively the cortical architecture for stereoscopic vision in two areas of macaque visual cortex. For primary visual cortex V1, the result is consistent with a module that is isotropic in cortical space with a diameter of at least 3 mm in surface extent. This implies that the module for stereo is larger than the repeat distance between ocular dominance columns in V1. By contrast, in the extrastriate cortical area V5/MT, which has a specialized architecture for stereo depth, the module for representation of stereo is about 1 mm in surface extent, so the representation of stereo in V5/MT is more compressed than V1 in terms of neural wiring of the neocortex. The surface extent estimated for stereo in V5/MT is consistent with measurements of its specialized domains for binocular disparity. Within V1, we suggest that long-range horizontal, anatomical connections form functional modules that serve both binocular and monocular pattern recognition: this common function may explain the distortion and disruption of monocular pattern vision observed in amblyopia. This article is part of the themed issue ‘Vision in our three-dimensional world’. PMID:27269604

  12. Tunnel Vision in Environmental Management.

    ERIC Educational Resources Information Center

    Miller, Alan

    1982-01-01

    Discusses problem-solving styles in environmental management and the specific deficiencies in these styles that might be grouped under the label "tunnel vision," a form of selective attention contributing to inadequate problem-formulation, partial solutions to complex problems, and generation of additional problems. Includes educational…

  13. Real-time vision systems

    SciTech Connect

    Johnson, R.; Hernandez, J.E.; Lu, Shin-yee

    1994-11-15

    Many industrial and defence applications require an ability to make instantaneous decisions based on sensor input of a time varying process. Such systems are referred to as `real-time systems` because they process and act on data as it occurs in time. When a vision sensor is used in a real-time system, the processing demands can be quite substantial, with typical data rates of 10-20 million samples per second. A real-time Machine Vision Laboratory (MVL) was established in FY94 to extend our years of experience in developing computer vision algorithms to include the development and implementation of real-time vision systems. The laboratory is equipped with a variety of hardware components, including Datacube image acquisition and processing boards, a Sun workstation, and several different types of CCD cameras, including monochrome and color area cameras and analog and digital line-scan cameras. The equipment is reconfigurable for prototyping different applications. This facility has been used to support several programs at LLNL, including O Division`s Peacemaker and Deadeye Projects as well as the CRADA with the U.S. Textile Industry, CAFE (Computer Aided Fabric Inspection). To date, we have successfully demonstrated several real-time applications: bullet tracking, stereo tracking and ranging, and web inspection. This work has been documented in the ongoing development of a real-time software library.

  14. North American Natural Gas Vision

    DTIC Science & Technology

    2005-01-01

    Pemex Comercio Internacional (Pemex International), responsible for international trade. 30 North American Natural Gas Vision In 1995, the...distribution of secondary petrochemical products; and Pemex Internacional , which is in charge of international trade. Comisión Reguladora de Energía

  15. Smart vision chips: An overview

    NASA Technical Reports Server (NTRS)

    Koch, Christof

    1994-01-01

    This viewgraph presentation presents four working analog VLSI vision chips: (1) time-derivative retina, (2) zero-crossing chip, (3) resistive fuse, and (4) figure-ground chip; work in progress on computing motion and neuromorphic systems; and conceptual and practical lessons learned.

  16. Metazoan opsin evolution reveals a simple route to animal vision

    PubMed Central

    Feuda, Roberto; Hamilton, Sinead C.; McInerney, James O.; Pisani, Davide

    2012-01-01

    All known visual pigments in Neuralia (Cnidaria, Ctenophora, and Bilateria) are composed of an opsin (a seven-transmembrane G protein-coupled receptor), and a light-sensitive chromophore, generally retinal. Accordingly, opsins play a key role in vision. There is no agreement on the relationships of the neuralian opsin subfamilies, and clarifying their phylogeny is key to elucidating the origin of this protein family and of vision. We used improved methods and data to resolve the opsin phylogeny and explain the evolution of animal vision. We found that the Placozoa have opsins, and that the opsins share a common ancestor with the melatonin receptors. Further to this, we found that all known neuralian opsins can be classified into the same three subfamilies into which the bilaterian opsins are classified: the ciliary (C), rhabdomeric (R), and go-coupled plus retinochrome, retinal G protein-coupled receptor (Go/RGR) opsins. Our results entail a simple scenario of opsin evolution. The first opsin originated from the duplication of the common ancestor of the melatonin and opsin genes in a eumetazoan (Placozoa plus Neuralia) ancestor, and an inference of its amino acid sequence suggests that this protein might not have been light-sensitive. Two more gene duplications in the ancestral neuralian lineage resulted in the origin of the R, C, and Go/RGR opsins. Accordingly, the first animal with at least a C, an R, and a Go/RGR opsin was a neuralian progenitor. PMID:23112152

  17. Metazoan opsin evolution reveals a simple route to animal vision.

    PubMed

    Feuda, Roberto; Hamilton, Sinead C; McInerney, James O; Pisani, Davide

    2012-11-13

    All known visual pigments in Neuralia (Cnidaria, Ctenophora, and Bilateria) are composed of an opsin (a seven-transmembrane G protein-coupled receptor), and a light-sensitive chromophore, generally retinal. Accordingly, opsins play a key role in vision. There is no agreement on the relationships of the neuralian opsin subfamilies, and clarifying their phylogeny is key to elucidating the origin of this protein family and of vision. We used improved methods and data to resolve the opsin phylogeny and explain the evolution of animal vision. We found that the Placozoa have opsins, and that the opsins share a common ancestor with the melatonin receptors. Further to this, we found that all known neuralian opsins can be classified into the same three subfamilies into which the bilaterian opsins are classified: the ciliary (C), rhabdomeric (R), and go-coupled plus retinochrome, retinal G protein-coupled receptor (Go/RGR) opsins. Our results entail a simple scenario of opsin evolution. The first opsin originated from the duplication of the common ancestor of the melatonin and opsin genes in a eumetazoan (Placozoa plus Neuralia) ancestor, and an inference of its amino acid sequence suggests that this protein might not have been light-sensitive. Two more gene duplications in the ancestral neuralian lineage resulted in the origin of the R, C, and Go/RGR opsins. Accordingly, the first animal with at least a C, an R, and a Go/RGR opsin was a neuralian progenitor.

  18. The Impact of Vision in Spatial Coding

    ERIC Educational Resources Information Center

    Papadopoulos, Konstantinos; Koustriava, Eleni

    2011-01-01

    The aim of this study is to examine the performance in coding and representing of near-space in relation to vision status (blindness vs. normal vision) and sensory modality (touch vs. vision). Forty-eight children and teenagers participated. Sixteen of the participants were totally blind or had only light perception, 16 were blindfolded sighted…

  19. Topographic Mapping of Residual Vision by Computer

    ERIC Educational Resources Information Center

    MacKeben, Manfred

    2008-01-01

    Many persons with low vision have diseases that damage the retina only in selected areas, which can lead to scotomas (blind spots) in perception. The most frequent of these diseases is age-related macular degeneration (AMD), in which foveal vision is often impaired by a central scotoma that impairs vision of fine detail and causes problems with…

  20. The Impact of Vision in Spatial Coding

    ERIC Educational Resources Information Center

    Papadopoulos, Konstantinos; Koustriava, Eleni

    2011-01-01

    The aim of this study is to examine the performance in coding and representing of near-space in relation to vision status (blindness vs. normal vision) and sensory modality (touch vs. vision). Forty-eight children and teenagers participated. Sixteen of the participants were totally blind or had only light perception, 16 were blindfolded sighted…

  1. The Efficacy of Optometric Vision Therapy.

    ERIC Educational Resources Information Center

    Journal of the American Optometric Association, 1988

    1988-01-01

    This review aims to document the efficacy and validity of vision therapy for modifying and improving vision functioning. The paper describes the essential components of the visual system and disorders which can be physiologically and clinically identified. Vision therapy is defined as a clinical approach for correcting and ameliorating the effects…

  2. The Development of Low Vision Therapist Certification.

    ERIC Educational Resources Information Center

    Watson, Gale R.; Quillman, R. Dee; Flax, Marshall; Gerritsen, Bryan

    1999-01-01

    Discusses the development and implementation of the low-vision-therapist certification through the Association for Education and Rehabilitation of the Blind and Visually Impaired. Credentials for professionals in low vision are described, along with required written examination, and the role of the low-vision therapist. (CR)

  3. Coaching Peripheral Vision Training for Soccer Athletes

    ERIC Educational Resources Information Center

    Marques, Nelson Kautzner, Jr.

    2010-01-01

    Brazilian Soccer began developing its current emphasis on peripheral vision in the late 1950s, by initiative of coach of the Canto do Rio Football Club, in Niteroi, Rio de Janeiro, a pioneer in the development of peripheral vision training in soccer players. Peripheral vision training gained world relevance when a young talent from Canto do Rio,…

  4. Coaching Peripheral Vision Training for Soccer Athletes

    ERIC Educational Resources Information Center

    Marques, Nelson Kautzner, Jr.

    2010-01-01

    Brazilian Soccer began developing its current emphasis on peripheral vision in the late 1950s, by initiative of coach of the Canto do Rio Football Club, in Niteroi, Rio de Janeiro, a pioneer in the development of peripheral vision training in soccer players. Peripheral vision training gained world relevance when a young talent from Canto do Rio,…

  5. The Visions of World-Class Universities

    ERIC Educational Resources Information Center

    Slyusarenko, Olena

    2015-01-01

    The visions of the top 26 world-class universities of the first 30 in the Shanghai ranking list have been evaluated and compared with the missions of the world's top 20 universities. Applying the content analysis, a group of 48 keywords, which describe the essence of these visions, has been revealed. The average amount of keywords in one vision is…

  6. The Jeffersonian Vision of Legal Education.

    ERIC Educational Resources Information Center

    Douglas, Davison M.

    2001-01-01

    Explores the Jeffersonian vision of legal education. Examines methods of training lawyers in colonial America, noting that colleges offered no such instruction. Considers Jefferson's vision of the role of education in sustaining a republican form of government and describes the implementation of his vision of legal education first at the college…

  7. The Efficacy of Optometric Vision Therapy.

    ERIC Educational Resources Information Center

    Journal of the American Optometric Association, 1988

    1988-01-01

    This review aims to document the efficacy and validity of vision therapy for modifying and improving vision functioning. The paper describes the essential components of the visual system and disorders which can be physiologically and clinically identified. Vision therapy is defined as a clinical approach for correcting and ameliorating the effects…

  8. Leadership: Vision & Structure. Resource Paper No. 36.

    ERIC Educational Resources Information Center

    Groff, Warren H.

    Research indicates that leaders tend to be remarkably well-balanced people who embody four areas of competency: vision, the ability to communicate that vision, positive self-regard, and the ability to build trust with associates. The process of creating a vision of the future requires an understanding of the opportunities and threats present in…

  9. Topographic Mapping of Residual Vision by Computer

    ERIC Educational Resources Information Center

    MacKeben, Manfred

    2008-01-01

    Many persons with low vision have diseases that damage the retina only in selected areas, which can lead to scotomas (blind spots) in perception. The most frequent of these diseases is age-related macular degeneration (AMD), in which foveal vision is often impaired by a central scotoma that impairs vision of fine detail and causes problems with…

  10. What Aspects of Vision Facilitate Haptic Processing?

    ERIC Educational Resources Information Center

    Millar, Susanna; Al-Attar, Zainab

    2005-01-01

    We investigate how vision affects haptic performance when task-relevant visual cues are reduced or excluded. The task was to remember the spatial location of six landmarks that were explored by touch in a tactile map. Here, we use specially designed spectacles that simulate residual peripheral vision, tunnel vision, diffuse light perception, and…

  11. The Visions of World-Class Universities

    ERIC Educational Resources Information Center

    Slyusarenko, Olena

    2015-01-01

    The visions of the top 26 world-class universities of the first 30 in the Shanghai ranking list have been evaluated and compared with the missions of the world's top 20 universities. Applying the content analysis, a group of 48 keywords, which describe the essence of these visions, has been revealed. The average amount of keywords in one vision is…

  12. Community Educators, Visions, and Educative Communities.

    ERIC Educational Resources Information Center

    Winecoff, Larry; Lyday, W. Jackson

    1991-01-01

    A framework for applying the vision-building process to community education includes (1) rationale for change and need for clear vision; (2) community profile; (3) new values and beliefs; (4) divergent thinking; (5) creating the vision; (6) building the roadmap; (7) enabling participation; and (8) restructuring communities. (SK)

  13. The Vision Thing in Higher Education.

    ERIC Educational Resources Information Center

    Keller, George

    1995-01-01

    It is argued that while the concept of "vision" in higher education has been met with disdain, criticism is based on misconceptions of vision's nature and role--that vision requires a charismatic administrator and that visionaries are dreamers. Educators and planners are urged to use imaginative thinking to connect the institution's and staff's…

  14. School Vision of Learning: Urban Setting

    ERIC Educational Resources Information Center

    Guy, Tiffany A.

    2010-01-01

    In this paper, the author develops her school vision of learning. She explains the theories she used to help develop the vision. The author then goes into detail on the methods she will use to make her vision for a school that prepares urban students for a successful life after high school. She takes into account all the stakeholders and how they…

  15. Transforming a School's Culture through Shared Vision.

    ERIC Educational Resources Information Center

    Smith, Stuart C.; Stolp, Stephen

    1995-01-01

    Although, theoretically, an organizational vision can unite school-community members, it can also destroy organizational culture without the consensus of those members. This publication offers guidelines for creating a collaborative vision--one that gives all members the opportunity to help create the vision. Each school should choose a strategy…

  16. What Aspects of Vision Facilitate Haptic Processing?

    ERIC Educational Resources Information Center

    Millar, Susanna; Al-Attar, Zainab

    2005-01-01

    We investigate how vision affects haptic performance when task-relevant visual cues are reduced or excluded. The task was to remember the spatial location of six landmarks that were explored by touch in a tactile map. Here, we use specially designed spectacles that simulate residual peripheral vision, tunnel vision, diffuse light perception, and…

  17. Opsin gene repertoires in northern archaic hominids.

    PubMed

    Taylor, John S; Reimchen, Thomas E

    2016-08-01

    The Neanderthals' northern distribution, hunting techniques, and orbit breadths suggest that they were more active in dim light than modern humans. We surveyed visual opsin genes from four Neanderthals and two other archaic hominids to see if they provided additional support for this hypothesis. This analysis was motivated by the observation that alleles responsible for anomalous trichromacy in humans are more common in northern latitudes, by data suggesting that these variants might enhance vision in mesopic conditions, and by the observation that dim light active species often have fewer opsin genes than diurnal relatives. We also looked for evidence of convergent amino acid substitutions in Neanderthal opsins and orthologs from crepuscular or nocturnal species. The Altai Neanderthal, the Denisovan, and the Ust'-Ishim early modern human had opsin genes that encoded proteins identical to orthologs in the human reference genome. Opsins from the Vindija Cave Neanderthals (three females) had many nonsynonymous substitutions, including several predicted to influence colour vision (e.g., stop codons). However, the functional implications of these observations were difficult to assess, given that "control" loci, where no substitutions were expected, differed from humans to the same extent. This left unresolved the test for colour vision deficiencies in Vindija Cave Neanderthals.

  18. Improved night vision demonstrator program status

    NASA Astrophysics Data System (ADS)

    Haran, Terence L.; James, J. Christopher; Roberts, David W.; Knotts, Michael E.; Wasilewski, Anthony A.; West, Leanne L.; Robinson, William G.; Bennett, Gisele

    2007-04-01

    Although existing night vision equipment provides a significant improvement in target detection in low light conditions, there are several limitations that limit their effectiveness. Focus is a significant problem for night vision equipment due to the low f-number optics required to obtain sufficient sensitivity as well as the dynamic nature of night vision applications, which requires frequent focus adjustments. The Georgia Tech Research Institute has developed a prototype next-generation night vision device called the Improved Night Vision Demonstrator (INVD) in order to address these shortfalls. This paper will describe the design of the INVD system as well as an analysis of its performance.

  19. Basic design principles of colorimetric vision systems

    NASA Astrophysics Data System (ADS)

    Mumzhiu, Alex M.

    1998-10-01

    Color measurement is an important part of overall production quality control in textile, coating, plastics, food, paper and other industries. The color measurement instruments such as colorimeters and spectrophotometers, used for production quality control have many limitations. In many applications they cannot be used for a variety of reasons and have to be replaced with human operators. Machine vision has great potential for color measurement. The components for color machine vision systems, such as broadcast quality 3-CCD cameras, fast and inexpensive PCI frame grabbers, and sophisticated image processing software packages are available. However the machine vision industry has only started to approach the color domain. The few color machine vision systems on the market, produced by the largest machine vision manufacturers have very limited capabilities. A lack of understanding that a vision based color measurement system could fail if it ignores the basic principles of colorimetry is the main reason for the slow progress of color vision systems. the purpose of this paper is to clarify how color measurement principles have to be applied to vision systems and how the electro-optical design features of colorimeters have to be modified in order to implement them for vision systems. The subject of this presentation far exceeds the limitations of a journal paper so only the most important aspects will be discussed. An overview of the major areas of applications for colorimetric vision system will be discussed. Finally, the reasons why some customers are happy with their vision systems and some are not will be analyzed.

  20. Digital item adaptation for color vision variations

    NASA Astrophysics Data System (ADS)

    Song, Jaeil; Yang, Seungji; Kim, Cheonseog; Nam, Jaeho; Hong, Jin-Woo; Ro, Yong Man

    2003-06-01

    As color is more widely used to carry visual information in the multimedia content, ability to perceive color plays a crucial role in getting visual information. Regardless of color vision variations, one should have visual information equally. This paper proposes the adaptation technique for color vision variations in the MPEG-21 Digital Item Adaptation (DIA). DIA is performed respectively for severe color vision deficiency (dichromats) and for mild color vision deficiency (anomalous trichromats), according to the description of user characteristics about color vision variations. Adapted images are tested by simulation program for color vision variations so as to recognize the appearance of the adapted images in the color deficient vision. Experimental result shows that proposed adaptation technique works well in the MPEG-21 framework.

  1. Evolution of colour vision in mammals.

    PubMed

    Jacobs, Gerald H

    2009-10-12

    Colour vision allows animals to reliably distinguish differences in the distributions of spectral energies reaching the eye. Although not universal, a capacity for colour vision is sufficiently widespread across the animal kingdom to provide prima facie evidence of its importance as a tool for analysing and interpreting the visual environment. The basic biological mechanisms on which vertebrate colour vision ultimately rests, the cone opsin genes and the photopigments they specify, are highly conserved. Within that constraint, however, the utilization of these basic elements varies in striking ways in that they appear, disappear and emerge in altered form during the course of evolution. These changes, along with other alterations in the visual system, have led to profound variations in the nature and salience of colour vision among the vertebrates. This article concerns the evolution of colour vision among the mammals, viewing that process in the context of relevant biological mechanisms, of variations in mammalian colour vision, and of the utility of colour vision.

  2. Understanding and preventing computer vision syndrome.

    PubMed

    Loh, Ky; Redd, Sc

    2008-01-01

    The invention of computer and advancement in information technology has revolutionized and benefited the society but at the same time has caused symptoms related to its usage such as ocular sprain, irritation, redness, dryness, blurred vision and double vision. This cluster of symptoms is known as computer vision syndrome which is characterized by the visual symptoms which result from interaction with computer display or its environment. Three major mechanisms that lead to computer vision syndrome are extraocular mechanism, accommodative mechanism and ocular surface mechanism. The visual effects of the computer such as brightness, resolution, glare and quality all are known factors that contribute to computer vision syndrome. Prevention is the most important strategy in managing computer vision syndrome. Modification in the ergonomics of the working environment, patient education and proper eye care are crucial in managing computer vision syndrome.

  3. VISION User Guide - VISION (Verifiable Fuel Cycle Simulation) Model

    SciTech Connect

    Jacob J. Jacobson; Robert F. Jeffers; Gretchen E. Matthern; Steven J. Piet; Benjamin A. Baker; Joseph Grimm

    2009-08-01

    The purpose of this document is to provide a guide for using the current version of the Verifiable Fuel Cycle Simulation (VISION) model. This is a complex model with many parameters; the user is strongly encouraged to read this user guide before attempting to run the model. This model is an R&D work in progress and may contain errors and omissions. It is based upon numerous assumptions. This model is intended to assist in evaluating “what if” scenarios and in comparing fuel, reactor, and fuel processing alternatives at a systems level for U.S. nuclear power. The model is not intended as a tool for process flow and design modeling of specific facilities nor for tracking individual units of fuel or other material through the system. The model is intended to examine the interactions among the components of a fuel system as a function of time varying system parameters; this model represents a dynamic rather than steady-state approximation of the nuclear fuel system. VISION models the nuclear cycle at the system level, not individual facilities, e.g., “reactor types” not individual reactors and “separation types” not individual separation plants. Natural uranium can be enriched, which produces enriched uranium, which goes into fuel fabrication, and depleted uranium (DU), which goes into storage. Fuel is transformed (transmuted) in reactors and then goes into a storage buffer. Used fuel can be pulled from storage into either separation of disposal. If sent to separations, fuel is transformed (partitioned) into fuel products, recovered uranium, and various categories of waste. Recycled material is stored until used by its assigned reactor type. Note that recovered uranium is itself often partitioned: some RU flows with recycled transuranic elements, some flows with wastes, and the rest is designated RU. RU comes out of storage if needed to correct the U/TRU ratio in new recycled fuel. Neither RU nor DU are designated as wastes. VISION is comprised of several

  4. Vision Aspects of Space Flight

    NASA Technical Reports Server (NTRS)

    Manuel, Keith; Billica, Roger (Technical Monitor)

    2000-01-01

    Vision, being one of our most important senses, is critically important in the unique working environment of space flight. Critical evaluation of the astronauts visual system begins with pre-selection examinations resulting in an average of 65% of all medical disqualification's caused by ocular findings. With an average age of 42, approximately 60% of the astronaut corps requires vision correction. Further demands of the unique training and working environment of microgravity, variable lighting from very poor to extreme brightness of sunlight and exposure to extremes of electromagnetic energy results in unique eyewear and contact lens applications. This presentation will describe some of those unique eyewear and contact lens applications used in space flight and training environments. Additionally, ocular findings from 26 shuttle and 5 MIR mission post-flight examinations will be presented.

  5. Computer vision in microstructural analysis

    NASA Technical Reports Server (NTRS)

    Srinivasan, Malur N.; Massarweh, W.; Hough, C. L.

    1992-01-01

    The following is a laboratory experiment designed to be performed by advanced-high school and beginning-college students. It is hoped that this experiment will create an interest in and further understanding of materials science. The objective of this experiment is to demonstrate that the microstructure of engineered materials is affected by the processing conditions in manufacture, and that it is possible to characterize the microstructure using image analysis with a computer. The principle of computer vision will first be introduced followed by the description of the system developed at Texas A&M University. This in turn will be followed by the description of the experiment to obtain differences in microstructure and the characterization of the microstructure using computer vision.

  6. The vision of David Marr.

    PubMed

    Stevens, Kent A

    2012-01-01

    Marr proposed a computational paradigm for studying the visual system, wherein aspects of vision would be amenable to study with what might be regarded a computational-reductionist approach. First, vision would be cleaved into separable 'computational theories', in which the visual system is characterized in terms of its computational goals and the strategies by which they are carried out. Each such computational theory could then be investigated in increasingly concrete terms, from symbols and measurements, to representations and algorithms, to processes and neural implementations. This paradigm rests on some general expectations of a symbolic information processing system, including his stated principles of explicit naming, modular design, least commitment, and graceful degradation. In retrospect, the computational framework also tacitly rests on additional assumptions about the nature of biological information processing: (1) separability of computational strategies, (2) separability of representations, (3) a pipeline nature of information processing, and that (4) the representations employ primitives of low dimensionality. These assumptions are discussed in this retrospective.

  7. Mitochondrial oxidative phosphorylation compensation may preserve vision in patients with OPA1-linked autosomal dominant optic atrophy.

    PubMed

    Van Bergen, Nicole J; Crowston, Jonathan G; Kearns, Lisa S; Staffieri, Sandra E; Hewitt, Alex W; Cohn, Amy C; Mackey, David A; Trounce, Ian A

    2011-01-01

    Autosomal Dominant Optic Atrophy (ADOA) is the most common inherited optic atrophy where vision impairment results from specific loss of retinal ganglion cells of the optic nerve. Around 60% of ADOA cases are linked to mutations in the OPA1 gene. OPA1 is a fission-fusion protein involved in mitochondrial inner membrane remodelling. ADOA presents with marked variation in clinical phenotype and varying degrees of vision loss, even among siblings carrying identical mutations in OPA1. To determine whether the degree of vision loss is associated with the level of mitochondrial impairment, we examined mitochondrial function in lymphoblast cell lines obtained from six large Australian OPA1-linked ADOA pedigrees. Comparing patients with severe vision loss (visual acuity [VA]<6/36) and patients with relatively preserved vision (VA>6/9) a clear defect in mitochondrial ATP synthesis and reduced respiration rates were observed in patients with poor vision. In addition, oxidative phosphorylation (OXPHOS) enzymology in ADOA patients with normal vision revealed increased complex II+III activity and levels of complex IV protein. These data suggest that OPA1 deficiency impairs OXPHOS efficiency, but compensation through increases in the distal complexes of the respiratory chain may preserve mitochondrial ATP production in patients who maintain normal vision. Identification of genetic variants that enable this response may provide novel therapeutic insights into OXPHOS compensation for preventing vision loss in optic neuropathies.

  8. Mitochondrial Oxidative Phosphorylation Compensation May Preserve Vision in Patients with OPA1-Linked Autosomal Dominant Optic Atrophy

    PubMed Central

    Van Bergen, Nicole J.; Crowston, Jonathan G.; Kearns, Lisa S.; Staffieri, Sandra E.; Hewitt, Alex W.; Cohn, Amy C.; Mackey, David A.; Trounce, Ian A.

    2011-01-01

    Autosomal Dominant Optic Atrophy (ADOA) is the most common inherited optic atrophy where vision impairment results from specific loss of retinal ganglion cells of the optic nerve. Around 60% of ADOA cases are linked to mutations in the OPA1 gene. OPA1 is a fission-fusion protein involved in mitochondrial inner membrane remodelling. ADOA presents with marked variation in clinical phenotype and varying degrees of vision loss, even among siblings carrying identical mutations in OPA1. To determine whether the degree of vision loss is associated with the level of mitochondrial impairment, we examined mitochondrial function in lymphoblast cell lines obtained from six large Australian OPA1-linked ADOA pedigrees. Comparing patients with severe vision loss (visual acuity [VA]<6/36) and patients with relatively preserved vision (VA>6/9) a clear defect in mitochondrial ATP synthesis and reduced respiration rates were observed in patients with poor vision. In addition, oxidative phosphorylation (OXPHOS) enzymology in ADOA patients with normal vision revealed increased complex II+III activity and levels of complex IV protein. These data suggest that OPA1 deficiency impairs OXPHOS efficiency, but compensation through increases in the distal complexes of the respiratory chain may preserve mitochondrial ATP production in patients who maintain normal vision. Identification of genetic variants that enable this response may provide novel therapeutic insights into OXPHOS compensation for preventing vision loss in optic neuropathies. PMID:21731710

  9. Learning disabilities, dyslexia, and vision.

    PubMed

    Handler, Sheryl M; Fierson, Walter M; Section on Ophthalmology

    2011-03-01

    Learning disabilities constitute a diverse group of disorders in which children who generally possess at least average intelligence have problems processing information or generating output. Their etiologies are multifactorial and reflect genetic influences and dysfunction of brain systems. Reading disability, or dyslexia, is the most common learning disability. It is a receptive language-based learning disability that is characterized by difficulties with decoding, fluent word recognition, rapid automatic naming, and/or reading-comprehension skills. These difficulties typically result from a deficit in the phonologic component of language that makes it difficult to use the alphabetic code to decode the written word. Early recognition and referral to qualified professionals for evidence-based evaluations and treatments are necessary to achieve the best possible outcome. Because dyslexia is a language-based disorder, treatment should be directed at this etiology. Remedial programs should include specific instruction in decoding, fluency training, vocabulary, and comprehension. Most programs include daily intensive individualized instruction that explicitly teaches phonemic awareness and the application of phonics. Vision problems can interfere with the process of reading, but children with dyslexia or related learning disabilities have the same visual function and ocular health as children without such conditions. Currently, there is inadequate scientific evidence to support the view that subtle eye or visual problems cause or increase the severity of learning disabilities. Because they are difficult for the public to understand and for educators to treat, learning disabilities have spawned a wide variety of scientifically unsupported vision-based diagnostic and treatment procedures. Scientific evidence does not support the claims that visual training, muscle exercises, ocular pursuit-and-tracking exercises, behavioral/perceptual vision therapy, "training" glasses

  10. Dynamical Systems and Motion Vision.

    DTIC Science & Technology

    1988-04-01

    TASK Artificial Inteligence Laboratory AREA I WORK UNIT NUMBERS 545 Technology Square . Cambridge, MA 02139 C\\ II. CONTROLLING OFFICE NAME ANO0 ADDRESS...INSTITUTE OF TECHNOLOGY ARTIFICIAL INTELLIGENCE LABORATORY A.I.Memo No. 1037 April, 1988 Dynamical Systems and Motion Vision Joachim Heel Abstract: In this... Artificial Intelligence L3 Laboratory of the Massachusetts Institute of Technology. Support for the Laboratory’s [1 Artificial Intelligence Research is

  11. Parallel Algorithms for Computer Vision

    DTIC Science & Technology

    1990-04-01

    Tikhonov and V. Y. Arsenin . Solutions of Ill - posed Problems . W.H.Winston, Washington, D.C., 1977 . [661 V. Torre... Ill - posed problems in early vision. Proceedings of the IEEE, 76:869-889, 1988. [4] J. Besag. Spatial interaction and the statistical analysis of lattice...Cooperative computation of stereo disparity. Science, 194:283-287, 1976. [50] J. Marroquin, S. Mitter, and T. Poggio. Probabilistic solution of ill - posed

  12. Vision Screening by Color Photography

    NASA Technical Reports Server (NTRS)

    Jayroe, R.; Richardson, J. R.; Kerr, J.; Hay, S.; Mcbride, R.

    1985-01-01

    Screening test developed for detecting a range of vision defects in eye, including common precursors to amblyopia. Test noninvasive, safe, and administered easily in field by operator with no medical training. Only minimal momentary cooperation of subject required: Thus, test shows promise for use with very young children. Test produces color-slide images of retinas of eyes under specially-controlled lighting conditions. Trained observer screens five children per minute.

  13. Procedures for Testing Color Vision,

    DTIC Science & Technology

    1981-01-01

    for the report were chosen for their special competences and with regard for appropriate balance. This report has been reviewed by a group other than...determine quantitatively whether the color-defective applicant was competent to make the color perception requirements of a particular job. The colors...reconnaissance des anomalies de la vision des couleurs. Archives des Maladies Professionnelles , de M6decine du Tray et de S~curit6 Sociale (Paris) 29:293-314

  14. Vision Screening by Color Photography

    NASA Technical Reports Server (NTRS)

    Jayroe, R.; Richardson, J. R.; Kerr, J.; Hay, S.; Mcbride, R.

    1985-01-01

    Screening test developed for detecting a range of vision defects in eye, including common precursors to amblyopia. Test noninvasive, safe, and administered easily in field by operator with no medical training. Only minimal momentary cooperation of subject required: Thus, test shows promise for use with very young children. Test produces color-slide images of retinas of eyes under specially-controlled lighting conditions. Trained observer screens five children per minute.

  15. Novel applications of hyperstereo vision

    NASA Astrophysics Data System (ADS)

    Watkins, Wendell R.; Jordan, Jay B.; Trivedi, Mohan M.

    1997-09-01

    Recent stereo vision experiments show potential in enhancing vehicular navigation, target acquisition, and optical turbulence mitigation. The experiments involved the use of stereo vision headsets connected to visible and 8-12 micrometers IR imagers. The imagers were separated by up to 50 m and equipped with telescopes for viewing at ranges of tens of meters up to 4 km. The important findings were: (1) human viewers were able to discern terrain undulations for obstacle avoidance, (2) human viewers were able to detect depth features within the scenes that enhanced the target acquisition process over using monocular viewing,and (3) human viewers noted appreciable reduction in the distortion effects of optical turbulence over that observed through a single monocular channel. For navigation, stereo goggles were developed for headset display and simultaneous direct vision for vehicular navigation enhancement. For detection, the depth cues can be used to detect even salient target features. For optical turbulence, the human mechanisms of fusing two views into a single perceived scene can be used to provide nearly undistorted perception. These experiments show significant improvement for many applications.

  16. Colour vision requirements of firefighters.

    PubMed

    Margrain, T H; Birch, J; Owen, C G

    1996-04-01

    To perform their job safely firefighters must be able to identify colours on industrial gas cylinders, portable fire extinguishers, road traffic signals and several pieces of firefighting equipment. Although good colour vision is necessary we believe that the existing colour vision standard, which bars entry to the fire service to applicants who fail more than two plates of the Ishihara test, is unnecessarily stringent. We have identified and quantified the colour coded information encountered by firefighters. Colours were plotted on the CIE chromaticity diagram (1931) and isochromatic zones, which document the colour confusions of colour deficient observers, superimposed. This novel technique established possible colour confusions in different types of colour deficiency. Analysis of the results showed that red/green dichromats (protanopes and deuteranopes), severe deuteranomalous trichromats who fail the Farnsworth D15 test, and protanomalous trichromats are unsuitable for firefighting work. However, people with slight deuteranomalous trichromatism who pass the D15 test, are not disadvantaged and can be employed safely as firefighters. A new colour vision standard and a new testing procedure is recommended.

  17. Ames vision group research overview

    NASA Technical Reports Server (NTRS)

    Watson, Andrew B.

    1990-01-01

    A major goal of the reseach group is to develop mathematical and computational models of early human vision. These models are valuable in the prediction of human performance, in the design of visual coding schemes and displays, and in robotic vision. To date researchers have models of retinal sampling, spatial processing in visual cortex, contrast sensitivity, and motion processing. Based on their models of early human vision, researchers developed several schemes for efficient coding and compression of monochrome and color images. These are pyramid schemes that decompose the image into features that vary in location, size, orientation, and phase. To determine the perceptual fidelity of these codes, researchers developed novel human testing methods that have received considerable attention in the research community. Researchers constructed models of human visual motion processing based on physiological and psychophysical data, and have tested these models through simulation and human experiments. They also explored the application of these biological algorithms to applications in automated guidance of rotorcraft and autonomous landing of spacecraft. Researchers developed networks for inhomogeneous image sampling, for pyramid coding of images, for automatic geometrical correction of disordered samples, and for removal of motion artifacts from unstable cameras.

  18. Artificial vision: principles and prospects.

    PubMed

    Gilhooley, Michael J; Acheson, James

    2017-02-01

    The aim of this article is to give an overview of the strategies and technologies currently under development to return vision to blind patients and will answer the question: What options exist for artificial vision in patients blind from retinal disease; how close are these to clinical practice? Retinal approaches will be the focus of this review as they are most advanced in terms not only of development, but entry into the imagination of the general public; they are technologies patients ask about, but may be less familiar to practicing neurologists.The prerequisites for retinal survivor cell stimulation are discussed, followed by consideration of the state of the art of four promising methods making use of this principle: electronic prostheses, stem cells, gene therapy and the developing field of ophthalmic optogenetics. Human applications of artificial vision by survivor cell stimulation are certainly with us in the research clinic and very close to commercialization and general use. This, together with their place in the public consciousness, makes the overview provided by this review particularly helpful to practicing neurologists.

  19. Information architecture. Volume 4: Vision

    SciTech Connect

    1998-03-01

    The Vision document marks the transition from definition to implementation of the Department of Energy (DOE) Information Architecture Program. A description of the possibilities for the future, supported by actual experience with a process model and tool set, points toward implementation options. The directions for future information technology investments are discussed. Practical examples of how technology answers the business and information needs of the organization through coordinated and meshed data, applications, and technology architectures are related. This document is the fourth and final volume in the planned series for defining and exhibiting the DOE information architecture. The targeted scope of this document includes DOE Program Offices, field sites, contractor-operated facilities, and laboratories. This document paints a picture of how, over the next 7 years, technology may be implemented, dramatically improving the ways business is conducted at DOE. While technology is mentioned throughout this document, the vision is not about technology. The vision concerns the transition afforded by technology and the process steps to be completed to ensure alignment with business needs. This goal can be met if those directing the changing business and mission-support processes understand the capabilities afforded by architectural processes.

  20. Vision-based aircraft guidance

    NASA Technical Reports Server (NTRS)

    Menon, P. K.

    1993-01-01

    Early research on the development of machine vision algorithms to serve as pilot aids in aircraft flight operations is discussed. The research is useful for synthesizing new cockpit instrumentation that can enhance flight safety and efficiency. With the present work as the basis, future research will produce low-cost instrument by integrating a conventional TV camera together with off-the=shelf digitizing hardware for flight test verification. Initial focus of the research will be on developing pilot aids for clear-night operations. Latter part of the research will examine synthetic vision issues for poor visibility flight operations. Both research efforts will contribute towards the high-speed civil transport aircraft program. It is anticipated that the research reported here will also produce pilot aids for conducting helicopter flight operations during emergency search and rescue. The primary emphasis of the present research effort is on near-term, flight demonstrable technologies. This report discusses pilot aids for night landing and takeoff and synthetic vision as an aid to low visibility landing.

  1. Night vision device technology development

    SciTech Connect

    Funsten, H.; Nordholt, J.; Suszcynsky, D.

    1998-12-31

    This is the final report of a two-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). This project sought to develop microchannel plate (MCP) technologies for enhancement of night vision device (NVD) capabilities. First, the authors addressed the need for segmented microchannel plates with independent gain control to minimize loss of low level light images in the presence of a bright light source (e.g., battlefield lasers, flares, and headlights). This would enable, for example, enhanced vision capabilities during night operations in a city environment and continuous capability of aviators to see the horizon, near-ground obstructions, and ground targets. Second, the authors addressed the need for curved microchannel plate technology to increase the field of view of NVDs while minimizing optical aberrations. This development would significantly enhance peripheral vision capabilities of aviators and result in easier adaptation of the human eye to NVDs. The authors have developed two technologies to overcome these problems, and they have initiated a collaborative effort with an industrial partner to develop a proof-of-principle prototype.

  2. Drosophila's view on insect vision.

    PubMed

    Borst, Alexander

    2009-01-13

    Within the last 400 million years, insects have radiated into at least a million species, accounting for more than half of all known living organisms: they are the most successful group in the animal kingdom, found in almost all environments of the planet, ranging in body size from a mere 0.1 mm up to half a meter. Their eyes, together with the respective parts of the nervous system dedicated to the processing of visual information, have long been the subject of intense investigation but, with the exception of some very basic reflexes, it is still not possible to link an insect's visual input to its behavioral output. Fortunately for the field, the fruit fly Drosophila is an insect, too. This genetic workhorse holds great promise for the insect vision field, offering the possibility of recording, suppressing or stimulating any single neuron in its nervous system. Here, I shall give a brief synopsis of what we currently know about insect vision, describe the genetic toolset available in Drosophila and give some recent examples of how the application of these tools have furthered our understanding of color and motion vision in Drosophila.

  3. Color vision of ancestral organisms of higher primates.

    PubMed

    Nei, M; Zhang, J; Yokoyama, S

    1997-06-01

    The color vision of mammals is controlled by photosensitive proteins called opsins. Most mammals have dichromatic color vision, but hominoids and Old World (OW) monkeys enjoy trichromatic vision, having the blue-, green-, and red-sensitive opsin genes. Most New World (NW) monkeys are either dichromatic or trichromatic, depending on the sex and genotype. Trichromacy in higher primates is believed to have evolved to facilitate the detection of yellow and red fruits against dappled foliage, but the process of evolutionary change from dichromacy to trichromacy is not well understood. Using the parsimony and the newly developed Bayesian methods, we inferred the amino acid sequences of opsins of ancestral organisms of higher primates. The results suggest that the ancestors of OW and NW monkeys lacked the green gene and that the green gene later evolved from the red gene. The fact that the red/green opsin gene has survived the long nocturnal stage of mammalian evolution and that it is under strong purifying selection in organisms that live in dark environments suggests that this gene has another important function in addition to color vision, probably the control of circadian rhythms.

  4. Beauty and cuteness in peripheral vision

    PubMed Central

    Kuraguchi, Kana; Ashida, Hiroshi

    2015-01-01

    Guo et al. (2011) showed that attractiveness was detectable in peripheral vision. Since there are different types of attractiveness (Rhodes, 2006), we investigated how beauty and cuteness are detected in peripheral vision with a brief presentation. Participants (n = 45) observed two Japanese female faces for 100 ms, then were asked to respond which face was more beautiful (or cuter). The results indicated that both beauty and cuteness were detectable in peripheral vision, but not in the same manner. Discrimination rates for judging beauty were invariant in peripheral and central vision, while discrimination rates for judging cuteness declined in peripheral vision as compared with central vision. This was not explained by lower resolution in peripheral vision. In addition, for male participants, it was more difficult to judge cuteness than beauty in peripheral vision, thus suggesting that gender differences can have a certain effect when judging cuteness. Therefore, central vision might be suitable for judging cuteness while judging beauty might not be affected by either central or peripheral vision. This might be related with the functional difference between beauty and cuteness. PMID:25999883

  5. Beauty and cuteness in peripheral vision.

    PubMed

    Kuraguchi, Kana; Ashida, Hiroshi

    2015-01-01

    Guo et al. (2011) showed that attractiveness was detectable in peripheral vision. Since there are different types of attractiveness (Rhodes, 2006), we investigated how beauty and cuteness are detected in peripheral vision with a brief presentation. Participants (n = 45) observed two Japanese female faces for 100 ms, then were asked to respond which face was more beautiful (or cuter). The results indicated that both beauty and cuteness were detectable in peripheral vision, but not in the same manner. Discrimination rates for judging beauty were invariant in peripheral and central vision, while discrimination rates for judging cuteness declined in peripheral vision as compared with central vision. This was not explained by lower resolution in peripheral vision. In addition, for male participants, it was more difficult to judge cuteness than beauty in peripheral vision, thus suggesting that gender differences can have a certain effect when judging cuteness. Therefore, central vision might be suitable for judging cuteness while judging beauty might not be affected by either central or peripheral vision. This might be related with the functional difference between beauty and cuteness.

  6. Primate photopigments and primate color vision.

    PubMed Central

    Jacobs, G H

    1996-01-01

    The past 15 years have brought much progress in our understanding of several basic features of primate color vision. There has been particular success in cataloging the spectral properties of the cone photopigments found in retinas of a number of primate species and in elucidating the relationship between cone opsin genes and their photopigment products. Direct studies of color vision show that there are several modal patterns of color vision among groupings of primates: (i) Old World monkeys, apes, and humans all enjoy trichromatic color vision, although the former two groups do not seem prone to the polymorphic variations in color vision that are characteristic of people; (ii) most species of New World monkeys are highly polymorphic, with individual animals having any of several types of dichromatic or trichromatic color vision; (iii) less is known about color vision in prosimians, but evidence suggests that at least some diurnal species have dichromatic color vision; and (iv) some nocturnal primates may lack color vision completely. In many cases the photopigments and photopigment gene arrangements underlying these patterns have been revealed and, as a result, hints are emerging about the evolution of color vision among the primates. PMID:8570598

  7. Artificial vision support system (AVS(2)) for improved prosthetic vision.

    PubMed

    Fink, Wolfgang; Tarbell, Mark A

    2014-11-01

    State-of-the-art and upcoming camera-driven, implanted artificial vision systems provide only tens to hundreds of electrodes, affording only limited visual perception for blind subjects. Therefore, real time image processing is crucial to enhance and optimize this limited perception. Since tens or hundreds of pixels/electrodes allow only for a very crude approximation of the typically megapixel optical resolution of the external camera image feed, the preservation and enhancement of contrast differences and transitions, such as edges, are especially important compared to picture details such as object texture. An Artificial Vision Support System (AVS(2)) is devised that displays the captured video stream in a pixelation conforming to the dimension of the epi-retinal implant electrode array. AVS(2), using efficient image processing modules, modifies the captured video stream in real time, enhancing 'present but hidden' objects to overcome inadequacies or extremes in the camera imagery. As a result, visual prosthesis carriers may now be able to discern such objects in their 'field-of-view', thus enabling mobility in environments that would otherwise be too hazardous to navigate. The image processing modules can be engaged repeatedly in a user-defined order, which is a unique capability. AVS(2) is directly applicable to any artificial vision system that is based on an imaging modality (video, infrared, sound, ultrasound, microwave, radar, etc.) as the first step in the stimulation/processing cascade, such as: retinal implants (i.e. epi-retinal, sub-retinal, suprachoroidal), optic nerve implants, cortical implants, electric tongue stimulators, or tactile stimulators.

  8. Spatial linear navigation: is vision necessary?

    PubMed

    Israël, I; Capelli, A; Priot, A-E; Giannopulu, I

    2013-10-25

    In order to analyze spatial linear navigation through a task of self-controlled reproduction, healthy participants were passively transported on a mobile robot at constant velocity, and then had to reproduce the imposed distance of 2-8m in two conditions: "with vision" and "without vision". Our hypothesis was that the reproduction of distances would be longer with than without visual information. Indeed, with visual information the reproduction of all distances was overshot. In the "without vision" condition the reproduced distances were quite close to the imposed ones, but only for the shortest distances (2 and 4m) as the longest ones were clearly undershot. With vision the reproduction error was less than 10% for all distances; however the error could be smaller without vision at short distances, and therefore vision was not necessary.

  9. The role of binocular vision in walking.

    PubMed

    Hayhoe, Mary; Gillam, Barbara; Chajka, Kelly; Vecellio, Elia

    2009-01-01

    Despite the extensive investigation of binocular and stereoscopic vision, relatively little is known about its importance in natural visually guided behavior. In this paper, we explored the role of binocular vision when walking over and around obstacles. We monitored eye position during the task as an indicator of the difference between monocular and binocular performances. We found that binocular vision clearly facilitates walking performance. Walkers were slowed by about 10% in monocular vision and raised their foot higher when stepping over obstacles. Although the location and sequence of the fixations did not change in monocular vision, the timing of the fixations relative to the actions was different. Subjects spent proportionately more time fixating the obstacles and fixated longer while guiding foot placement near an obstacle. The data are consistent with greater uncertainty in monocular vision, leading to a greater reliance on feedback in the control of the movements.

  10. Standards for vision science libraries: 2014 revision

    PubMed Central

    Motte, Kristin; Caldwell, C. Brooke; Lamson, Karen S.; Ferimer, Suzanne; Nims, J. Chris

    2014-01-01

    Objective: This Association of Vision Science Librarians revision of the “Standards for Vision Science Libraries” aspires to provide benchmarks to address the needs for the services and resources of modern vision science libraries (academic, medical or hospital, pharmaceutical, and so on), which share a core mission, are varied by type, and are located throughout the world. Methods: Through multiple meeting discussions, member surveys, and a collaborative revision process, the standards have been updated for the first time in over a decade. Results: While the range of types of libraries supporting vision science services, education, and research is wide, all libraries, regardless of type, share core attributes, which the standards address. Conclusions: The current standards can and should be used to help develop new vision science libraries or to expand the growth of existing libraries, as well as to support vision science librarians in their work to better provide services and resources to their respective users. PMID:25349547

  11. Application-oriented robotic vision - A review

    NASA Astrophysics Data System (ADS)

    Jarvis, R. A.

    1984-01-01

    It is pointed out that computer vision is essentially concerned with emulating on a computational apparatus the process of 'seeing', which is naturally manifested in biological systems. Computer vision is part of the artificial intelligence field within the subcategory of machine perception. The present investigation has the objective to clarify, with the aid of examples, the issues surrounding application oriented robotic vision systems, taking into account also directions of development which promise to provide powerful industrial vision tools at an acceptable price. An entire robotic system is considered as a hierarchy of functional blocks representing an artificial hand/eye coordination faculty. Attention is given to scene analysis problem classes, binary vision systems, grey tone image analysis, three-dimensional scene analysis, three-dimensional volumetric modeling, and optimal collision-free path analysis. New VLSI-related developments will support robotic vision at a cost sufficiently low for applications in industry.

  12. Standards for vision science libraries: 2014 revision.

    PubMed

    Motte, Kristin; Caldwell, C Brooke; Lamson, Karen S; Ferimer, Suzanne; Nims, J Chris

    2014-10-01

    This Association of Vision Science Librarians revision of the "Standards for Vision Science Libraries" aspires to provide benchmarks to address the needs for the services and resources of modern vision science libraries (academic, medical or hospital, pharmaceutical, and so on), which share a core mission, are varied by type, and are located throughout the world. Through multiple meeting discussions, member surveys, and a collaborative revision process, the standards have been updated for the first time in over a decade. While the range of types of libraries supporting vision science services, education, and research is wide, all libraries, regardless of type, share core attributes, which the standards address. The current standards can and should be used to help develop new vision science libraries or to expand the growth of existing libraries, as well as to support vision science librarians in their work to better provide services and resources to their respective users.

  13. Cooperative and asynchronous stereo vision for dynamic vision sensors

    NASA Astrophysics Data System (ADS)

    Piatkowska, E.; Belbachir, A. N.; Gelautz, M.

    2014-05-01

    Dynamic vision sensors (DVSs) encode visual input as a stream of events generated upon relative light intensity changes in the scene. These sensors have the advantage of allowing simultaneously high temporal resolution (better than 10 µs) and wide dynamic range (>120 dB) at sparse data representation, which is not possible with clocked vision sensors. In this paper, we focus on the task of stereo reconstruction. The spatiotemporal and asynchronous aspects of data provided by the sensor impose a different stereo reconstruction approach from the one applied for synchronous frame-based cameras. We propose to model the event-driven stereo matching by a cooperative network (Marr and Poggio 1976 Science 194 283-7). The history of the recent activity in the scene is stored in the network, which serves as spatiotemporal context used in disparity calculation for each incoming event. The network constantly evolves in time, as events are generated. In our work, not only the spatiotemporal aspect of the data is preserved but also the matching is performed asynchronously. The results of the experiments prove that the proposed approach is well adapted for DVS data and can be successfully used for disparity calculation.

  14. Vision and vision-related outcome measures in multiple sclerosis.

    PubMed

    Balcer, Laura J; Miller, David H; Reingold, Stephen C; Cohen, Jeffrey A

    2015-01-01

    Visual impairment is a key manifestation of multiple sclerosis. Acute optic neuritis is a common, often presenting manifestation, but visual deficits and structural loss of retinal axonal and neuronal integrity can occur even without a history of optic neuritis. Interest in vision in multiple sclerosis is growing, partially in response to the development of sensitive visual function tests, structural markers such as optical coherence tomography and magnetic resonance imaging, and quality of life measures that give clinical meaning to the structure-function correlations that are unique to the afferent visual pathway. Abnormal eye movements also are common in multiple sclerosis, but quantitative assessment methods that can be applied in practice and clinical trials are not readily available. We summarize here a comprehensive literature search and the discussion at a recent international meeting of investigators involved in the development and study of visual outcomes in multiple sclerosis, which had, as its overriding goals, to review the state of the field and identify areas for future research. We review data and principles to help us understand the importance of vision as a model for outcomes assessment in clinical practice and therapeutic trials in multiple sclerosis.

  15. Vision and vision-related outcome measures in multiple sclerosis

    PubMed Central

    Balcer, Laura J.; Miller, David H.; Reingold, Stephen C.

    2015-01-01

    Visual impairment is a key manifestation of multiple sclerosis. Acute optic neuritis is a common, often presenting manifestation, but visual deficits and structural loss of retinal axonal and neuronal integrity can occur even without a history of optic neuritis. Interest in vision in multiple sclerosis is growing, partially in response to the development of sensitive visual function tests, structural markers such as optical coherence tomography and magnetic resonance imaging, and quality of life measures that give clinical meaning to the structure-function correlations that are unique to the afferent visual pathway. Abnormal eye movements also are common in multiple sclerosis, but quantitative assessment methods that can be applied in practice and clinical trials are not readily available. We summarize here a comprehensive literature search and the discussion at a recent international meeting of investigators involved in the development and study of visual outcomes in multiple sclerosis, which had, as its overriding goals, to review the state of the field and identify areas for future research. We review data and principles to help us understand the importance of vision as a model for outcomes assessment in clinical practice and therapeutic trials in multiple sclerosis. PMID:25433914

  16. Women and the vision thing.

    PubMed

    Ibarra, Herminia; Obodaru, Otilia

    2009-01-01

    Are women rated lower than men in evaluations of their leadership capabilities because of lingering gender bias? No, according to an analysis of thousands of 360-degree assessments collected by Insead's executive education program. That analysis showed that women tend to outshine men in all areas but one: vision. Unfortunately, that exception is a big one. At the top tiers of management, the ability to see opportunities, craft strategy based on a broad view of the business, and inspire others is a must-have. To explore the nature of the deficit, and whether it is a perception or reality, Insead professor Ibarra and doctoral candidate Obodaru interviewed female executives and studied the evaluation data. They developed three possible explanations. First, women may do just as much as men to shape the future but go about it in a different way; a leader who is less directive, includes more people, and shares credit might not fit people's mental model of a visionary. Second, women may believe they have less license to go out on a limb. Those who have built careers on detail-focused, shoulder-to-the-wheel execution may hesitate to stray from facts into unprovable assertions about the future. Third, women may choose not to cultivate reputations as big visionaries. Having seen bluster passed off as vision, they may dismiss the importance of selling visions. The top two candidates for the Democratic nomination for U.S. president in 2008 offer an instructive parallel. The runner-up, Hillary Clinton, was viewed as a get-it-done type with an impressive, if uninspiring, grasp of policy detail. The winner, Barack Obama, was seen as a charismatic visionary offering a hopeful, if undetailed, future. The good news is that every dimension of leadership is learned, not inborn. As more women become skilled at, and known for, envisioning the future, nothing will hold them back.

  17. The Berkeley Rudimentary Vision Test.

    PubMed

    Bailey, Ian L; Jackson, A Jonathan; Minto, Hasan; Greer, Robert B; Chu, Marlena A

    2012-09-01

    Very poor visual acuity often cannot be measured with letter charts even at close viewing distances. The Berkeley Rudimentary Vision Test (BRVT) was developed as a simple test to extend the range of visual acuity measurement beyond the limits of letter charts by systematically simplifying the visual task and using close viewing distances to achieve large angular sizes. The test has three pairs of hinged cards, 25 cm square. One card-pair has four single tumbling E (STE) optotypes at sizes 100 M, 63 M, 40 M, and 25 M. Another card-pair has four grating acuity (GA) targets at sizes 200 M, 125 M, 80 M, and 50 M. The third card-pair has a test of white field projection (WFP) and a test of black white discrimination (BWD). As a demonstration of feasibility, a population of subjects with severe visual impairment was tested with the BRVT. Adults with severe visual impairments from a wide variety of causes were recruited from three different rehabilitation programs. Vision measurements were made on 54 eyes from 37 subjects; test administration times were measured. For this population, letter chart visual acuity could be measured on 24 eyes. Measurements of visual acuity for STE targets were made for 18 eyes and with GA targets, for two eyes. Five eyes had WFP, and one had BWD. Four had light perception only. The median testing time with the BRVT was 2.5 min. The BRVT extends the range of visual acuity up to logMAR = 2.60 (20/8000) for STEs, to logMAR = 2.90 (20/16,000) for gratings and includes the WFP and BWD tests. The BRVT is a simple and efficient test of spatial vision that, with 13 increments, extends the range of measurement from the limits of the letter chart up to light perception.

  18. A conceptual model for vision rehabilitation

    PubMed Central

    Roberts, Pamela S.; Rizzo, John-Ross; Hreha, Kimberly; Wertheimer, Jeffrey; Kaldenberg, Jennifer; Hironaka, Dawn; Riggs, Richard; Colenbrander, August

    2017-01-01

    Vision impairments are highly prevalent after acquired brain injury (ABI). Conceptual models that focus on constructing intellectual frameworks greatly facilitate comprehension and implementation of practice guidelines in an interprofessional setting. The purpose of this article is to provide a review of the vision literature in ABI, describe a conceptual model for vision rehabilitation, explain its potential clinical inferences, and discuss its translation into rehabilitation across multiple practice settings and disciplines. PMID:27997671

  19. Low Vision Rehabilitation in Older Adults

    PubMed Central

    Özen Tunay, Zuhal; İdil, Aysun; Seza Petriçli, İkbal; Özdemir, Özdemir

    2016-01-01

    Objectives: To evaluate the diagnosis distribution, low vision rehabilitation methods and utilization of low vision rehabilitation in partially sighted persons over 65 years old. Materials and Methods: One hundred thirty-nine partially sighted geriatric patients aged 65 years or older were enrolled to the study between May 2012 and September 2013. Patients’ age, gender and the distribution of diagnosis were recorded. The visual acuity of the patients both for near and distance were examined with and without low vision devices and the methods of low vision rehabilitation were evaluated. Results: The mean age of the patients was 79.7 years and the median age was 80 years. Ninety-six (69.1%) of the patients were male and 43 (30.9%) were female. According to the distribution of diagnosis, the most frequent diagnosis was senile macular degeneration for both presenile and senile age groups. The mean best corrected visual acuity for distance was 0.92±0.37 logMAR and 4.75±3.47 M for near. The most frequently used low vision rehabilitation methods were telescopic glasses (59.0%) for distance and hyperocular glasses (66.9%) for near vision. A significant improvement in visual acuity both for distance and near vision were determined with low vision aids. Conclusion: The causes of low vision in presenile and senile patients in our study were similar to those of patients from developed countries. A significant improvement in visual acuity can be achieved both for distance and near vision with low vision rehabilitation in partially sighted geriatric patients. It is important to guide them to low vision rehabilitation. PMID:27800274

  20. Night vision: changing the way we drive

    NASA Astrophysics Data System (ADS)

    Klapper, Stuart H.; Kyle, Robert J. S.; Nicklin, Robert L.; Kormos, Alexander L.

    2001-03-01

    A revolutionary new Night Vision System has been designed to help drivers see well beyond their headlights. From luxury automobiles to heavy trucks, Night Vision is helping drivers see better, see further, and react sooner. This paper describes how Night Vision Systems are being used in transportation and their viability for the future. It describes recent improvements to the system currently in the second year of production. It also addresses consumer education and awareness, cost reduction, product reliability, market expansion and future improvements.

  1. Quaternions in computer vision and robotics

    SciTech Connect

    Pervin, E.; Webb, J.A.

    1982-01-01

    Computer vision and robotics suffer from not having good tools for manipulating three-dimensional objects. Vectors, coordinate geometry, and trigonometry all have deficiencies. Quaternions can be used to solve many of these problems. Many properties of quaternions that are relevant to computer vision and robotics are developed. Examples are given showing how quaternions can be used to simplify derivations in computer vision and robotics.

  2. Enhanced Night Vision Goggle Customer Test

    DTIC Science & Technology

    2006-08-01

    Enhanced Night Vision Goggle Customer Test by Christian B. Carstens, Charles C. Bonnett, and Elizabeth S. Redden ARL-TR-3839 August...Ground, MD 21005-5425 ARL-TR-3839 August 2006 Enhanced Night Vision Goggle Customer Test Christian B. Carstens, Charles C. Bonnett...NUMBER 4. TITLE AND SUBTITLE Enhanced Night Vision Goggle Customer Test 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 62716AH70 5e

  3. Convergence insufficiency and vision therapy.

    PubMed

    McGregor, Mary Lou

    2014-06-01

    There is no standard meaning of the term "vision therapy", and for this reason it is often a controversial topic between some members of the ophthalmic and optometric community. Most pediatric ophthalmologists avoid using the term because it is nonspecific. Convergence Insufficiency (CI) is a binocular visual problem that causes problems and symptoms with near fixation. There is consensus among eye care professionals that convergence therapy is effective in treating CI. Convergence therapy is not effective in treating learning disabilities, but can sometimes relieve symptoms that might be a barrier to reading. Copyright © 2014 Elsevier Inc. All rights reserved.

  4. Vision inspection system and method

    NASA Technical Reports Server (NTRS)

    Huber, Edward D. (Inventor); Williams, Rick A. (Inventor)

    1997-01-01

    An optical vision inspection system (4) and method for multiplexed illuminating, viewing, analyzing and recording a range of characteristically different kinds of defects, depressions, and ridges in a selected material surface (7) with first and second alternating optical subsystems (20, 21) illuminating and sensing successive frames of the same material surface patch. To detect the different kinds of surface features including abrupt as well as gradual surface variations, correspondingly different kinds of lighting are applied in time-multiplexed fashion to the common surface area patches under observation.

  5. Industrial Combustion Vision: A Vision by and for the Industrial Combustion Community

    SciTech Connect

    none,

    1998-05-01

    The Industrial Combustion Vision is the result of a collaborative effort by manufacturers and users of burners, boilers, furnaces, and other process heating equipment. The vision sets bold targets for tomorrow's combustion systems.

  6. Biological Basis For Computer Vision: Some Perspectives

    NASA Astrophysics Data System (ADS)

    Gupta, Madan M.

    1990-03-01

    Using biology as a basis for the development of sensors, devices and computer vision systems is a challenge to systems and vision scientists. It is also a field of promising research for engineering applications. Biological sensory systems, such as vision, touch and hearing, sense different physical phenomena from our environment, yet they possess some common mathematical functions. These mathematical functions are cast into the neural layers which are distributed throughout our sensory regions, sensory information transmission channels and in the cortex, the centre of perception. In this paper, we are concerned with the study of the biological vision system and the emulation of some of its mathematical functions, both retinal and visual cortex, for the development of a robust computer vision system. This field of research is not only intriguing, but offers a great challenge to systems scientists in the development of functional algorithms. These functional algorithms can be generalized for further studies in such fields as signal processing, control systems and image processing. Our studies are heavily dependent on the the use of fuzzy - neural layers and generalized receptive fields. Building blocks of such neural layers and receptive fields may lead to the design of better sensors and better computer vision systems. It is hoped that these studies will lead to the development of better artificial vision systems with various applications to vision prosthesis for the blind, robotic vision, medical imaging, medical sensors, industrial automation, remote sensing, space stations and ocean exploration.

  7. Vernier acuity through night vision goggles.

    PubMed

    Rabin, J

    1993-08-01

    Night vision goggles (NVG's) are being used increasingly in military and civilian environments. Despite the use of these devices, relatively few tests exist to assess visual performance through NVG's. Hyperacuity tasks may provide a sensitive index of performance through night vision devices. In this study, grating vernier acuity was measured through NVG's. As reported previously, a power law relation was observed between vernier acuity and stimulus contrast. Comparison of vernier acuity with and without NVG's indicated that performance is limited by the contrast transfer of the device. Vernier acuity measurements can be used to assess the quality of vision and quantity of contrast transferred through night vision devices.

  8. Simulating vision with and without macular disease.

    PubMed

    Marmor, David J; Marmor, Michael F

    2010-01-01

    Conventional photographs do not show how, at any moment of visual fixation, neural vision is clear only in the foveal center. We have developed new computer simulations to show both normal vision and vision with macular disease. These simulations show the nature of momentary vision for life tasks such as reading, facial recognition, and walking in the street. They also dramatically show the impact of macular disease (with scotomas and visual distortion), as there is no surrounding region of clarity. We hope these images will be instructive to both physicians and patients.

  9. Holographic optogenetic stimulation of patterned neuronal activity for vision restoration.

    PubMed

    Reutsky-Gefen, Inna; Golan, Lior; Farah, Nairouz; Schejter, Adi; Tsur, Limor; Brosh, Inbar; Shoham, Shy

    2013-01-01

    When natural photoreception is disrupted, as in outer-retinal degenerative diseases, artificial stimulation of surviving nerve cells offers a potential strategy for bypassing compromised neural circuits. Recently, light-sensitive proteins that photosensitize quiescent neurons have generated unprecedented opportunities for optogenetic neuronal control, inspiring early development of optical retinal prostheses. Selectively exciting large neural populations are essential for eliciting meaningful perceptions in the brain. Here we provide the first demonstration of holographic photo-stimulation strategies for bionic vision restoration. In blind retinas, we demonstrate reliable holographically patterned optogenetic stimulation of retinal ganglion cells with millisecond temporal precision and cellular resolution. Holographic excitation strategies could enable flexible control over distributed neuronal circuits, potentially paving the way towards high-acuity vision restoration devices and additional medical and scientific neuro-photonics applications.

  10. Night Mobility Instruction for Child with Low Vision.

    ERIC Educational Resources Information Center

    Tapp, Kenneth L.

    1985-01-01

    The challenges of after-dark travel for low vision children are examined in terms of physical effects of low light on normal and abnormal vision and consequences for low vision travel and orientation skills. Techniques for efficient vision use are suggested along with night travel aids and considerations in night driver vision. (CL)

  11. An Rx for 20/20 Vision: Vision Planning and Education.

    ERIC Educational Resources Information Center

    Chrisman, Gerald J.; Holliday, Clifford R.

    1996-01-01

    Discusses the Dallas Independent School District's decision to adopt an integrated technology infrastructure and the importance of vision planning for long term goals. Outlines the vision planning process: first draft; environmental projection; restatement of vision in terms of market projections, anticipated customer needs, suspected competitor…

  12. An Rx for 20/20 Vision: Vision Planning and Education.

    ERIC Educational Resources Information Center

    Chrisman, Gerald J.; Holliday, Clifford R.

    1996-01-01

    Discusses the Dallas Independent School District's decision to adopt an integrated technology infrastructure and the importance of vision planning for long term goals. Outlines the vision planning process: first draft; environmental projection; restatement of vision in terms of market projections, anticipated customer needs, suspected competitor…

  13. The Pedagogy of Teaching Educational Vision: A Vision Coach's Field Notes about Leaders as Learners

    ERIC Educational Resources Information Center

    Schein, Jeffrey

    2009-01-01

    The emerging field of educational visioning is full of challenges and phenomena worthy of careful analysis and documentation. A relatively neglected phenomenon is the learning curve of the leaders (often lay leaders) involved in the visioning process. This article documents a range of experiences of the author serving as a vision coach to five…

  14. The Pedagogy of Teaching Educational Vision: A Vision Coach's Field Notes about Leaders as Learners

    ERIC Educational Resources Information Center

    Schein, Jeffrey

    2009-01-01

    The emerging field of educational visioning is full of challenges and phenomena worthy of careful analysis and documentation. A relatively neglected phenomenon is the learning curve of the leaders (often lay leaders) involved in the visioning process. This article documents a range of experiences of the author serving as a vision coach to five…

  15. Leadership with a Vision: How Principals Develop and Implement Their Visions for School Success.

    ERIC Educational Resources Information Center

    Renchler, Ron

    1991-01-01

    Developing and pursuing a "vision" for school success is a crucial part of effective educational leadership. This document explores theoretical models of vision for school success and leadership forces in education; discusses principals as visionary leaders; offers practical advice on developing, implementing, and maintaining a vision for one's…

  16. Three-dimensional vision system

    NASA Astrophysics Data System (ADS)

    Tyrsa, Valentin E.; Burtseva, Larisa P.; Tyrsa, Vera; Kalaykov, Ivan; Ananiev, Anani

    2002-10-01

    A relief image focusing system is proposed here, contrary to the normal focusing systems using a flat image. The relief is mapping the panorama's depth by a scale depending on the objective parameters. Opposite to normal understanding, the relief is not static. It is formed synchronously with the forward-backward linear motion of the objective. Each pixel of the vision sensor is illuminated and interference of light waves takes place. As the objective moves, the intensity of the interfered optical signal changes between the internal sensor noise level and certain maximum as a function of time. The process of forming the signal in the relief image space is based on searching extremes of interfered optical signals at each pixel. A method of mapping the measurement scale of a monocular focusing distance-meter is presented in the paper. It is implemented by sampling the signals, digital measurement of the time intervals and the signals' amplitudes and joint processing of the obtained numerical values providing a limited error to portions of micron. The method contributes the vision systems to perceive panoramic view in wide distance ranges. It can work at a wide range of optical signals and is invariant to aberrations.

  17. Vision as a user interface

    NASA Astrophysics Data System (ADS)

    Koenderink, Jan

    2011-03-01

    The egg-rolling behavior of the graylag goose is an often quoted example of a fixed-action pattern. The bird will even attempt to roll a brick back to its nest! Despite excellent visual acuity it apparently takes a brick for an egg." Evolution optimizes utility, not veridicality. Yet textbooks take it for a fact that human vision evolved so as to approach veridical perception. How do humans manage to dodge the laws of evolution? I will show that they don't, but that human vision is an idiosyncratic user interface. By way of an example I consider the case of pictorial perception. Gleaning information from still images is an important human ability and is likely to remain so for the foreseeable future. I will discuss a number of instances of extreme non-veridicality and huge inter-observer variability. Despite their importance in applications (information dissemination, personnel selection,...) such huge effects have remained undocumented in the literature, although they can be traced to artistic conventions. The reason appears to be that conventional psychophysics-by design-fails to address the qualitative, that is the meaningful, aspects of visual awareness whereas this is the very target of the visual arts.

  18. Synthetic vision display evaluation studies

    NASA Technical Reports Server (NTRS)

    Regal, David M.; Whittington, David H.

    1994-01-01

    The goal of this research was to help us understand the display requirements for a synthetic vision system for the High Speed Civil Transport (HSCT). Four experiments were conducted to examine the effects of different levels of perceptual cue complexity in displays used by pilots in a flare and landing task. Increased levels of texture mapping of terrain and runway produced mixed results, including harder but shorter landings and a lower flare initiation altitude. Under higher workload conditions, increased texture resulted in an improvement in performance. An increase in familiar size cues did not result in improved performance. Only a small difference was found between displays using two patterns of high resolution texture mapping. The effects of increased perceptual cue complexity on performance was not as strong as would be predicted from the pilot's subjective reports or from related literature. A description of the role of a synthetic vision system in the High Speed Civil Transport is provide along with a literature review covering applied research related to perceptual cue usage in aircraft displays.

  19. Spatial Vision in Bombus terrestris

    PubMed Central

    Chakravarthi, Aravin; Baird, Emily; Dacke, Marie; Kelber, Almut

    2016-01-01

    Bombus terrestris is one of the most commonly used insect models to investigate visually guided behavior and spatial vision in particular. Two fundamental measures of spatial vision are spatial resolution and contrast sensitivity. In this study, we report the threshold of spatial resolution in B. terrestris and characterize the contrast sensitivity function of the bumblebee visual system for a dual choice discrimination task. We trained bumblebees in a Y-maze experimental set-up to associate a vertical sinusoidal grating with a sucrose reward, and a horizontal grating with absence of a reward. Using a logistic psychometric function, we estimated a resolution threshold of 0.21 cycles deg−1 of visual angle. This resolution is in the same range but slightly lower than that found in honeybees (Apis mellifera and A. cerana) and another bumblebee species (B. impatiens). We also found that the contrast sensitivity of B. terrestris was 1.57 for the spatial frequency 0.090 cycles deg−1 and 1.26 for 0.18 cycles deg−1. PMID:26912998

  20. Drop volume measurements by vision

    NASA Astrophysics Data System (ADS)

    Hugli, Heinz; Gonzalez, Jose J.

    2000-03-01

    A specific configuration for liquid flow metrology consists of a flow of falling drops coupled with a preferred measuring method that derives the flow directly from the drop count. Given the inaccuracy of this counting method, alternative methods have been proposed that measure the volume of each falling drop. The principle consists in deriving the volume from geometric measurements obtained by vision and the basic problem can be described as the estimation of the volume of a drop from its projection. This paper reviews methods previously used and provides an analysis of qualitative and quantitative aspects of drop volume estimation for flow metrology. Three drop shape models and the related volume estimation methods are defined in a first part. A second part is devoted to an experimental analysis of drop shape variations. In a final experimental part, the presented methods are compared and the good performance of a volume measurement method is experimentally demonstrated. It shows a rms-error of 1% in normal measurement conditions. These figures speak for the interest of the measurement by vision and represent a good base for predicting the suitability of the method in various applications.

  1. Computer vision syndrome: A review.

    PubMed

    Gowrisankaran, Sowjanya; Sheedy, James E

    2015-01-01

    Computer vision syndrome (CVS) is a collection of symptoms related to prolonged work at a computer display. This article reviews the current knowledge about the symptoms, related factors and treatment modalities for CVS. Relevant literature on CVS published during the past 65 years was analyzed. Symptoms reported by computer users are classified into internal ocular symptoms (strain and ache), external ocular symptoms (dryness, irritation, burning), visual symptoms (blur, double vision) and musculoskeletal symptoms (neck and shoulder pain). The major factors associated with CVS are either environmental (improper lighting, display position and viewing distance) and/or dependent on the user's visual abilities (uncorrected refractive error, oculomotor disorders and tear film abnormalities). Although the factors associated with CVS have been identified the physiological mechanisms that underlie CVS are not completely understood. Additionally, advances in technology have led to the increased use of hand-held devices, which might impose somewhat different visual challenges compared to desktop displays. Further research is required to better understand the physiological mechanisms underlying CVS and symptoms associated with the use of hand-held and stereoscopic displays.

  2. Advanced integrated enhanced vision systems

    NASA Astrophysics Data System (ADS)

    Kerr, J. R.; Luk, Chiu H.; Hammerstrom, Dan; Pavel, Misha

    2003-09-01

    In anticipation of its ultimate role in transport, business and rotary wing aircraft, we clarify the role of Enhanced Vision Systems (EVS): how the output data will be utilized, appropriate architecture for total avionics integration, pilot and control interfaces, and operational utilization. Ground-map (database) correlation is critical, and we suggest that "synthetic vision" is simply a subset of the monitor/guidance interface issue. The core of integrated EVS is its sensor processor. In order to approximate optimal, Bayesian multi-sensor fusion and ground correlation functionality in real time, we are developing a neural net approach utilizing human visual pathway and self-organizing, associative-engine processing. In addition to EVS/SVS imagery, outputs will include sensor-based navigation and attitude signals as well as hazard detection. A system architecture is described, encompassing an all-weather sensor suite; advanced processing technology; intertial, GPS and other avionics inputs; and pilot and machine interfaces. Issues of total-system accuracy and integrity are addressed, as well as flight operational aspects relating to both civil certification and military applications in IMC.

  3. Disparity channels in early vision

    PubMed Central

    Roe, AW; Parker, AJ; Born, RT; DeAngelis, GC

    2008-01-01

    The last decade has seen a dramatic increase in our knowledge of the neural basis of stereopsis. New cortical areas have been found to represent binocular disparities, new representations of disparity information (e.g., relative disparity signals) have been uncovered, the first topographic maps of disparity have been measured, and the first causal links between neural activity and depth perception have been established. Equally exciting is the finding that training and experience affects how signals are channeled through different brain areas, a flexibility that may be crucial for learning, plasticity, and recovery of function. The collective efforts of several laboratories have established stereo vision as one of the most productive model systems for elucidating the neural basis of perception. Much remains to be learned about how the disparity signals that are initially encoded in primary visual cortex are routed to and processed by extrastriate areas to mediate the diverse capacities of 3D vision that enhance our daily experience of the world. PMID:17978018

  4. VISION 21 SYSTEMS ANALYSIS METHODOLOGIES

    SciTech Connect

    G.S. Samuelsen; A. Rao; F. Robson; B. Washom

    2003-08-11

    Under the sponsorship of the U.S. Department of Energy/National Energy Technology Laboratory, a multi-disciplinary team led by the Advanced Power and Energy Program of the University of California at Irvine is defining the system engineering issues associated with the integration of key components and subsystems into power plant systems that meet performance and emission goals of the Vision 21 program. The study efforts have narrowed down the myriad of fuel processing, power generation, and emission control technologies to selected scenarios that identify those combinations having the potential to achieve the Vision 21 program goals of high efficiency and minimized environmental impact while using fossil fuels. The technology levels considered are based on projected technical and manufacturing advances being made in industry and on advances identified in current and future government supported research. Included in these advanced systems are solid oxide fuel cells and advanced cycle gas turbines. The results of this investigation will serve as a guide for the U. S. Department of Energy in identifying the research areas and technologies that warrant further support.

  5. Disparity channels in early vision.

    PubMed

    Roe, Anna W; Parker, Andrew J; Born, Richard T; DeAngelis, Gregory C

    2007-10-31

    The past decade has seen a dramatic increase in our knowledge of the neural basis of stereopsis. New cortical areas have been found to represent binocular disparities, new representations of disparity information (e.g., relative disparity signals) have been uncovered, the first topographic maps of disparity have been measured, and the first causal links between neural activity and depth perception have been established. Equally exciting is the finding that training and experience affects how signals are channeled through different brain areas, a flexibility that may be crucial for learning, plasticity, and recovery of function. The collective efforts of several laboratories have established stereo vision as one of the most productive model systems for elucidating the neural basis of perception. Much remains to be learned about how the disparity signals that are initially encoded in primary visual cortex are routed to and processed by extrastriate areas to mediate the diverse capacities of three-dimensional vision that enhance our daily experience of the world.

  6. Early vision and focal attention

    NASA Astrophysics Data System (ADS)

    Julesz, Bela

    1991-07-01

    At the thirty-year anniversary of the introduction of the technique of computer-generated random-dot stereograms and random-dot cinematograms into psychology, the impact of the technique on brain research and on the study of artificial intelligence is reviewed. The main finding-that stereoscopic depth perception (stereopsis), motion perception, and preattentive texture discrimination are basically bottom-up processes, which occur without the help of the top-down processes of cognition and semantic memory-greatly simplifies the study of these processes of early vision and permits the linking of human perception with monkey neurophysiology. Particularly interesting are the unexpected findings that stereopsis (assumed to be local) is a global process, while texture discrimination (assumed to be a global process, governed by statistics) is local, based on some conspicuous local features (textons). It is shown that the top-down process of "shape (depth) from shading" does not affect stereopsis, and some of the models of machine vision are evaluated. The asymmetry effect of human texture discrimination is discussed, together with recent nonlinear spatial filter models and a novel extension of the texton theory that can cope with the asymmetry problem. This didactic review attempts to introduce the physicist to the field of psychobiology and its problems-including metascientific problems of brain research, problems of scientific creativity, the state of artificial intelligence research (including connectionist neural networks) aimed at modeling brain activity, and the fundamental role of focal attention in mental events.

  7. Influence of Vision on Ocular Comfort Ratings.

    PubMed

    Rao, Subam Basuthkar Sundar; Simpson, Trefford L

    2016-08-01

    To evaluate the influence of blur on ocular comfort while systematically manipulating vision using habitual refractive correction, induced spatial blur, dioptric defocus, and under the absence of visual structure. Twenty emmetropic subjects rated vision, ocular comfort, and other sensations (burning, itching, and warmth) under clear viewing condition, spatial blur, and dioptric defocus, each lasting for 5 min. During each condition, subjects viewed digital targets projected from a distance of 3 m, and vision and ocular sensations were rated using magnitude estimation. Dioptric defocus was induced using +6.00DS contact lens, and equivalent spatial blur was produced by spatially filtering the targets. In a separate study, 15 participants rated vision and comfort while viewing a ganzfeld and behind an occluding patch (each of which provided an absence of visual structure) in addition to the above experimental conditions. Repeated-measures analysis of variance was used to compare the ratings of vision and comfort under the different experimental conditions. Vision under blurred conditions (both spatial blur and dioptric defocus) was rated significantly different (p < 0.001) from clear viewing condition. Vision was significantly different when targets were dioptrically defocused than when they were spatially blurred (p < 0.001). Ratings of comfort showed significant differences between clear and blurred conditions (p < 0.001). However, there was no significant difference in comfort ratings between dioptric defocus and spatial blur (p value at least 0.28). There were also no differences in comfort (p value at least 0.99) between clear vision, ganzfeld viewing, and occlusion despite the lack of visual structure in the latter two conditions. There does seem to be an association between clarity of vision and ocular comfort. Although the pathways for ocular surface pain and vision are perhaps exclusive, complex psychological influences such as nocebo or Hawthorne effects can

  8. Proceedings of the First International Optogenetic Therapies for Vision Symposium

    PubMed Central

    Francis, Peter J.; Mansfield, Brian; Rose, Stephen

    2013-01-01

    Optogenetics is a research field that uses gene therapy to deliver a gene encoding a light-activated protein to cells providing light-regulated control of targeted cell pathways. The technology is a popular tool in many fields of neuroscience, used to transiently switch cells on and off, for example, to map neural circuits. In inherited retinal degenerative diseases, where loss of vision results from the loss of photoreceptors, optogenetics can be applied to either augment the function of surviving photoreceptors or confer light sensitivity to naturally nonlight sensitive retinal cells, such as a bipolar cells. This can be achieved either by the light sensitive protein integrating with native internal signaling pathways, or by using a dual function membrane protein that integrates light signaling with an ion channel or pump activity. Exposing treated cells to light of the correct wavelength activates the protein, resulting in cellular depolarization or hyperpolarization that triggers neurological signaling to the visual cortex. While there is a lot of interest in optogenetics as a pan-disease clinical treatment for end-stage application in the inherited degenerative diseases of the retina, research to date has been limited to nonhuman clinical studies. To address the clinical translational needs of this technology, the Foundation Fighting Blindness and Massachusetts Eye and Ear Infirmary cohosted an International Optogenetic Therapies for Vision Workshop, which was held at Massachusetts Eye and Ear Infirmary, Boston, Massachusetts on June 1, 2012. PMID:24349882

  9. Organizational vision: experience at the unit level.

    PubMed

    Kukkurainen, Marja Leena; Suominen, Tarja; Rankinen, Sirkku; Härkönen, Eeva; Kuokkanen, Liisa

    2012-10-01

    The main focus of this follow-up study was to describe how the vision statements were perceived to describe the work in the units and what kind of relationships there were between the vision statements and background factors during the 3-year follow-up. he vision statement gives a competitive advantage to the organization. It helps find the desired direction during a period of transformation in the organization. Satisfaction, empowerment and motivation are challenged in the vision-realization process. he data were gathered by questionnaire from the multidisciplinary team members on three occasions. The response rate was 58% (n = 115, n = 112) for the first and second data sets, and 53% (n = 103) for the third data set. The data was analysed statistically. The organizational vision was perceived as quite stable during the 3 years. Factors associated with the vision statement at the end of the 3-year period were workload, experience of stress, work motivation, work satisfaction, importance of work independence and general empowerment. eaders are able to sustain the vision statement by motivating and empowering the staff. Empowerment especially is worth reinforcing in a vision-realization process. © 2011 Blackwell Publishing Ltd.

  10. Color Vision Deficits and Literacy Acquisition.

    ERIC Educational Resources Information Center

    Hurley, Sandra Rollins

    1994-01-01

    Shows that color blindness, whether partial or total, inhibits literacy acquisition. Offers a case study of a third grader with impaired color vision. Presents a review of literature on the topic. Notes that people with color vision deficits are often unaware of the handicap. (RS)

  11. Color Vision Deficiencies in Children. United States.

    ERIC Educational Resources Information Center

    National Center for Health Statistics (DHEW/PHS), Hyattsville, MD.

    Presented are prevalence data on color vision deficiencies (color blindness) in noninstitutionalized children, aged 6-11, in the United States, as estimated from the Health Examination Survey findings on a representative sample of over 7,400 children. Described are the two color vision tests used in the survey, the Ishihara Test for Color…

  12. The Institutional Vision of Tribal Community Colleges

    ERIC Educational Resources Information Center

    Abelman, Robert

    2011-01-01

    This investigation provides a base-line measurement of the inspirational and pragmatic rhetoric in declarations of institutional vision at tribal community colleges. By comparing it to nontribal community colleges, this content analysis reveals the current state of utility of the mission and vision statements of tribal community colleges, their…

  13. A Low Vision Reading Comprehension Test.

    ERIC Educational Resources Information Center

    Watson, G. R.; And Others

    1996-01-01

    Fifty adults (ages 28-86) with macular degeneration were given the Low Vision Reading Comprehension Assessment (LVRCA) to test its reliability and validity in evaluating the reading comprehension of those with vision impairments. The LVRCA was found to take only nine minutes to administer and was a valid and reliable tool. (CR)

  14. A vision for modernizing environmental risk assessment

    EPA Science Inventory

    In 2007, the US National Research Council (NRC) published a Vision and Strategy for [human health] Toxicity Testing in the 21st century. Central to the vision was increased reliance on high throughput in vitro testing and predictive approaches based on mechanistic understanding o...

  15. Multilevel Relaxation in Low Level Computer Vision.

    DTIC Science & Technology

    1982-01-01

    Lab, Cambridge,MA, June,1981. HR80 Hanson,A. and Riseman,E.M., Processing Cones: A Computational Structure for Image Analysis, In: Structured Computer Vision...Klinger,A. (Editors), Structured Computer Vision: Machine Perception through Hierarchical Computation Structures, Academic Press, New York, 1980. TP75

  16. Assessing the binocular advantage in aided vision.

    PubMed

    Harrington, Lawrence K; McIntire, John P; Hopper, Darrel G

    2014-09-01

    Advances in microsensors, microprocessors, and microdisplays are creating new opportunities for improving vision in degraded environments through the use of head-mounted displays. Initially, the cutting-edge technology used in these new displays will be expensive. Inevitably, the cost of providing the additional sensor and processing required to support binocularity brings the value of binocularity into question. Several assessments comparing binocular, binocular, and monocular head-mounted displays for aided vision have concluded that the additional performance, if any, provided by binocular head-mounted displays does not justify the cost. The selection of a biocular [corrected] display for use in the F-35 is a current example of this recurring decision process. It is possible that the human binocularity advantage does not carry over to the aided vision application, but more likely the experimental approaches used in the past have been too coarse to measure its subtle but important benefits. Evaluating the value of binocularity in aided vision applications requires an understanding of the characteristics of both human vision and head-mounted displays. With this understanding, the value of binocularity in aided vision can be estimated and experimental evidence can be collected to confirm or reject the presumed binocular advantage, enabling improved decisions in aided vision system design. This paper describes four computational approaches-geometry of stereopsis, modulation transfer function area for stereopsis, probability summation, and binocular summation-that may be useful in quantifying the advantage of binocularity in aided vision.

  17. The "Vision Thing" and School Restructuring.

    ERIC Educational Resources Information Center

    Conley, David T.; And Others

    1992-01-01

    This article explores the role of vision and vision-building in public schools as a tool for bringing about a redirection of educational institutions. A reanalysis of 32 interviews with teachers and principals in schools involved in Oregon's "2020 School Improvement and Professional Development" program revealed that most school goals…

  18. Implementing Vision Research in Special Needs Education

    ERIC Educational Resources Information Center

    Wilhelmsen, Gunvor Birkeland; Aanstad, Monica L.; Leirvik, Eva Iren B.

    2015-01-01

    This article presents experiences from vision research implemented in education and argues for the need for teachers with visual competence and insight into suitable methods for stimulation and learning. A new type of continuing professional development (CPD) focuses on the role of vision in children's learning and development, the consequences of…

  19. From Academic Vision to Physical Manifestation

    ERIC Educational Resources Information Center

    Walleri, R. Dan; Becker, William E.

    2004-01-01

    This community college-based case study describes and analyzes how a new mission and vision adopted by the college trustees was translated into a facility master plan. The vision is designed to serve the needs of the community and facilitate economic development, especially in the areas of health occupations, biotechnology and…

  20. Color Vision Deficits and Literacy Acquisition.

    ERIC Educational Resources Information Center

    Hurley, Sandra Rollins

    1994-01-01

    Shows that color blindness, whether partial or total, inhibits literacy acquisition. Offers a case study of a third grader with impaired color vision. Presents a review of literature on the topic. Notes that people with color vision deficits are often unaware of the handicap. (RS)