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Sample records for direct digital synthesizer

  1. Numerically Controlled Phase Locked Loop Using Direct Digital Synthesizer

    SciTech Connect

    Pei, Alex

    1993-04-13

    A direct digital synthesizer is a highly stable digitally controlled frequency generator that outputs high spectrum purity rf signals. Because of the all digital design, it is immune to various environmental disturbances that plague conventional LC based VCOs. As a result, a PLL based on DDS can achieve high spectrum purity with very narrow tracking bandwidth.

  2. Note: Directly measuring the direct digital synthesizer frequency chirp-rate for an atom interferometer.

    PubMed

    Tao, Juan-Juan; Zhou, Min-Kang; Zhang, Qiao-Zhen; Cui, Jia-Feng; Duan, Xiao-Chun; Shao, Cheng-Gang; Hu, Zhong-Kun

    2015-09-01

    During gravity measurements with Raman type atom interferometry, the frequency of the laser used to drive Raman transition is scanned by chirping the frequency of a direct digital synthesizer (DDS), and the local gravity is determined by precisely measuring the chip rate α of DDS. We present an effective method that can directly evaluate the frequency chirp rate stability of our DDS. By mixing a pair of synchronous linear sweeping signals, the chirp rate fluctuation is precisely measured with a frequency counter. The measurement result shows that the relative α instability can reach 5.7 × 10(-11) in 1 s, which is neglectable in a 10(-9) g level atom interferometry gravimeter.

  3. Note: Directly measuring the direct digital synthesizer frequency chirp-rate for an atom interferometer

    SciTech Connect

    Tao, Juan-Juan; Zhou, Min-Kang E-mail: zmk@hust.edu.cn; Zhang, Qiao-Zhen; Cui, Jia-Feng; Duan, Xiao-Chun; Shao, Cheng-Gang; Hu, Zhong-Kun E-mail: zmk@hust.edu.cn

    2015-09-15

    During gravity measurements with Raman type atom interferometry, the frequency of the laser used to drive Raman transition is scanned by chirping the frequency of a direct digital synthesizer (DDS), and the local gravity is determined by precisely measuring the chip rate α of DDS. We present an effective method that can directly evaluate the frequency chirp rate stability of our DDS. By mixing a pair of synchronous linear sweeping signals, the chirp rate fluctuation is precisely measured with a frequency counter. The measurement result shows that the relative α instability can reach 5.7 × 10{sup −11} in 1 s, which is neglectable in a 10{sup −9} g level atom interferometry gravimeter.

  4. A ROM-less direct digital frequency synthesizer based on hybrid polynomial approximation.

    PubMed

    Omran, Qahtan Khalaf; Islam, Mohammad Tariqul; Misran, Norbahiah; Faruque, Mohammad Rashed Iqbal

    2014-01-01

    In this paper, a novel design approach for a phase to sinusoid amplitude converter (PSAC) has been investigated. Two segments have been used to approximate the first sine quadrant. A first linear segment is used to fit the region near the zero point, while a second fourth-order parabolic segment is used to approximate the rest of the sine curve. The phase sample, where the polynomial changed, was chosen in such a way as to achieve the maximum spurious free dynamic range (SFDR). The invented direct digital frequency synthesizer (DDFS) has been encoded in VHDL and post simulation was carried out. The synthesized architecture exhibits a promising result of 90 dBc SFDR. The targeted structure is expected to show advantages for perceptible reduction of hardware resources and power consumption as well as high clock speeds.

  5. A ROM-Less Direct Digital Frequency Synthesizer Based on Hybrid Polynomial Approximation

    PubMed Central

    Omran, Qahtan Khalaf; Islam, Mohammad Tariqul; Misran, Norbahiah; Faruque, Mohammad Rashed Iqbal

    2014-01-01

    In this paper, a novel design approach for a phase to sinusoid amplitude converter (PSAC) has been investigated. Two segments have been used to approximate the first sine quadrant. A first linear segment is used to fit the region near the zero point, while a second fourth-order parabolic segment is used to approximate the rest of the sine curve. The phase sample, where the polynomial changed, was chosen in such a way as to achieve the maximum spurious free dynamic range (SFDR). The invented direct digital frequency synthesizer (DDFS) has been encoded in VHDL and post simulation was carried out. The synthesized architecture exhibits a promising result of 90 dBc SFDR. The targeted structure is expected to show advantages for perceptible reduction of hardware resources and power consumption as well as high clock speeds. PMID:24892092

  6. Hardware Implementation of 32-Bit High-Speed Direct Digital Frequency Synthesizer

    PubMed Central

    Ibrahim, Salah Hasan; Ali, Sawal Hamid Md.; Islam, Md. Shabiul

    2014-01-01

    The design and implementation of a high-speed direct digital frequency synthesizer are presented. A modified Brent-Kung parallel adder is combined with pipelining technique to improve the speed of the system. A gated clock technique is proposed to reduce the number of registers in the phase accumulator design. The quarter wave symmetry technique is used to store only one quarter of the sine wave. The ROM lookup table (LUT) is partitioned into three 4-bit sub-ROMs based on angular decomposition technique and trigonometric identity. Exploiting the advantages of sine-cosine symmetrical attributes together with XOR logic gates, one sub-ROM block can be removed from the design. These techniques, compressed the ROM into 368 bits. The ROM compressed ratio is 534.2 : 1, with only two adders, two multipliers, and XOR-gates with high frequency resolution of 0.029 Hz. These techniques make the direct digital frequency synthesizer an attractive candidate for wireless communication applications. PMID:24991635

  7. Hardware implementation of 32-bit high-speed direct digital frequency synthesizer.

    PubMed

    Ibrahim, Salah Hasan; Ali, Sawal Hamid Md; Islam, Md Shabiul

    2014-01-01

    The design and implementation of a high-speed direct digital frequency synthesizer are presented. A modified Brent-Kung parallel adder is combined with pipelining technique to improve the speed of the system. A gated clock technique is proposed to reduce the number of registers in the phase accumulator design. The quarter wave symmetry technique is used to store only one quarter of the sine wave. The ROM lookup table (LUT) is partitioned into three 4-bit sub-ROMs based on angular decomposition technique and trigonometric identity. Exploiting the advantages of sine-cosine symmetrical attributes together with XOR logic gates, one sub-ROM block can be removed from the design. These techniques, compressed the ROM into 368 bits. The ROM compressed ratio is 534.2:1, with only two adders, two multipliers, and XOR-gates with high frequency resolution of 0.029 Hz. These techniques make the direct digital frequency synthesizer an attractive candidate for wireless communication applications.

  8. Software Defined Radio (SDR) and Direct Digital Synthesizer (DDS) for NMR/MRI instruments at low-field.

    PubMed

    Asfour, Aktham; Raoof, Kosai; Yonnet, Jean-Paul

    2013-11-27

    A proof-of-concept of the use of a fully digital radiofrequency (RF) electronics for the design of dedicated Nuclear Magnetic Resonance (NMR) systems at low-field (0.1 T) is presented. This digital electronics is based on the use of three key elements: a Direct Digital Synthesizer (DDS) for pulse generation, a Software Defined Radio (SDR) for a digital receiving of NMR signals and a Digital Signal Processor (DSP) for system control and for the generation of the gradient signals (pulse programmer). The SDR includes a direct analog-to-digital conversion and a Digital Down Conversion (digital quadrature demodulation, decimation filtering, processing gain…). The various aspects of the concept and of the realization are addressed with some details. These include both hardware design and software considerations. One of the underlying ideas is to enable such NMR systems to "enjoy" from existing advanced technology that have been realized in other research areas, especially in telecommunication domain. Another goal is to make these systems easy to build and replicate so as to help research groups in realizing dedicated NMR desktops for a large palette of new applications. We also would like to give readers an idea of the current trends in this field. The performances of the developed electronics are discussed throughout the paper. First FID (Free Induction Decay) signals are also presented. Some development perspectives of our work in the area of low-field NMR/MRI will be finally addressed.

  9. Software Defined Radio (SDR) and Direct Digital Synthesizer (DDS) for NMR/MRI Instruments at Low-Field

    PubMed Central

    Asfour, Aktham; Raoof, Kosai; Yonnet, Jean-Paul

    2013-01-01

    A proof-of-concept of the use of a fully digital radiofrequency (RF) electronics for the design of dedicated Nuclear Magnetic Resonance (NMR) systems at low-field (0.1 T) is presented. This digital electronics is based on the use of three key elements: a Direct Digital Synthesizer (DDS) for pulse generation, a Software Defined Radio (SDR) for a digital receiving of NMR signals and a Digital Signal Processor (DSP) for system control and for the generation of the gradient signals (pulse programmer). The SDR includes a direct analog-to-digital conversion and a Digital Down Conversion (digital quadrature demodulation, decimation filtering, processing gain…). The various aspects of the concept and of the realization are addressed with some details. These include both hardware design and software considerations. One of the underlying ideas is to enable such NMR systems to “enjoy” from existing advanced technology that have been realized in other research areas, especially in telecommunication domain. Another goal is to make these systems easy to build and replicate so as to help research groups in realizing dedicated NMR desktops for a large palette of new applications. We also would like to give readers an idea of the current trends in this field. The performances of the developed electronics are discussed throughout the paper. First FID (Free Induction Decay) signals are also presented. Some development perspectives of our work in the area of low-field NMR/MRI will be finally addressed. PMID:24287540

  10. Note: A high-frequency signal generator based on direct digital synthesizer and field-programmable gate array.

    PubMed

    Du, Yuanbo; Li, Wenbing; Ge, Yapeng; Li, Hui; Deng, Ke; Lu, Zehuang

    2017-09-01

    A high-frequency signal generator based on direct digital synthesizer (DDS) and field-programmable gate array (FPGA) is presented. The FPGA provides the controlling time sequence for the DDS, which has a highest output frequency of 1.4 GHz and a frequency resolution of 190 pHz. At an output frequency of 1.2 GHz, the measured phase noise, including the contribution of the reference clock, is -65 dBc/Hz@1 Hz, while the intrinsic phase noise is -82 dBc/Hz@1 Hz. Time delay of the DDS is measured to be less than 150 ns. The signal generator is used to drive an acousto-optic modulator, and the rise time due to the whole link is 24 ns. The developed signal generator can be used in many precision measurement experiments in the fields of atomic, molecular, and optical physics.

  11. Note: A high-frequency signal generator based on direct digital synthesizer and field-programmable gate array

    NASA Astrophysics Data System (ADS)

    Du, Yuanbo; Li, Wenbing; Ge, Yapeng; Li, Hui; Deng, Ke; Lu, Zehuang

    2017-09-01

    A high-frequency signal generator based on direct digital synthesizer (DDS) and field-programmable gate array (FPGA) is presented. The FPGA provides the controlling time sequence for the DDS, which has a highest output frequency of 1.4 GHz and a frequency resolution of 190 pHz. At an output frequency of 1.2 GHz, the measured phase noise, including the contribution of the reference clock, is -65 dBc/Hz@1 Hz, while the intrinsic phase noise is -82 dBc/Hz@1 Hz. Time delay of the DDS is measured to be less than 150 ns. The signal generator is used to drive an acousto-optic modulator, and the rise time due to the whole link is 24 ns. The developed signal generator can be used in many precision measurement experiments in the fields of atomic, molecular, and optical physics.

  12. Optimization and Implementation of Scaling-Free CORDIC-Based Direct Digital Frequency Synthesizer for Body Care Area Network Systems

    PubMed Central

    Juang, Ying-Shen; Ko, Lu-Ting; Chen, Jwu-E.; Sung, Tze-Yun; Hsin, Hsi-Chin

    2012-01-01

    Coordinate rotation digital computer (CORDIC) is an efficient algorithm for computations of trigonometric functions. Scaling-free-CORDIC is one of the famous CORDIC implementations with advantages of speed and area. In this paper, a novel direct digital frequency synthesizer (DDFS) based on scaling-free CORDIC is presented. The proposed multiplier-less architecture with small ROM and pipeline data path has advantages of high data rate, high precision, high performance, and less hardware cost. The design procedure with performance and hardware analysis for optimization has also been given. It is verified by Matlab simulations and then implemented with field programmable gate array (FPGA) by Verilog. The spurious-free dynamic range (SFDR) is over 86.85 dBc, and the signal-to-noise ratio (SNR) is more than 81.12 dB. The scaling-free CORDIC-based architecture is suitable for VLSI implementations for the DDFS applications in terms of hardware cost, power consumption, SNR, and SFDR. The proposed DDFS is very suitable for medical instruments and body care area network systems. PMID:23251230

  13. Optimization and implementation of scaling-free CORDIC-based direct digital frequency synthesizer for body care area network systems.

    PubMed

    Juang, Ying-Shen; Ko, Lu-Ting; Chen, Jwu-E; Sung, Tze-Yun; Hsin, Hsi-Chin

    2012-01-01

    Coordinate rotation digital computer (CORDIC) is an efficient algorithm for computations of trigonometric functions. Scaling-free-CORDIC is one of the famous CORDIC implementations with advantages of speed and area. In this paper, a novel direct digital frequency synthesizer (DDFS) based on scaling-free CORDIC is presented. The proposed multiplier-less architecture with small ROM and pipeline data path has advantages of high data rate, high precision, high performance, and less hardware cost. The design procedure with performance and hardware analysis for optimization has also been given. It is verified by Matlab simulations and then implemented with field programmable gate array (FPGA) by Verilog. The spurious-free dynamic range (SFDR) is over 86.85 dBc, and the signal-to-noise ratio (SNR) is more than 81.12 dB. The scaling-free CORDIC-based architecture is suitable for VLSI implementations for the DDFS applications in terms of hardware cost, power consumption, SNR, and SFDR. The proposed DDFS is very suitable for medical instruments and body care area network systems.

  14. Digital Frequency Synthesizer For Radar Astronomy

    NASA Technical Reports Server (NTRS)

    Sadr, Ramin; Satorius, Edgar; Robinett, J. Loris, Jr.; Olson, Erlend

    1992-01-01

    Report discusses conceptual digital frequency synthesizer part of programmable local oscillator in radar-astronomy system. Phase must remain continuous during adjustments of frequency, phase noise must be low, and spectral purity must be high. Discusses theory of operation in some mathematical detail and presents new analysis of spectral purity of output.

  15. Digital frequency synthesizer for radar astronomy

    NASA Technical Reports Server (NTRS)

    Sadr, R.; Satorius, E.; Robinett, L.; Olson, E.

    1990-01-01

    The digital frequency synthesizer (DFS) is an integral part of the programmable local oscillator (PLO) which is being developed for the NASA's Deep Space Network (DSN) and radar astronomy. Here, the theory of operation and the design of the DFS are discussed, and the design parameters in application for the Goldstone Solar System Radar (GSSR) are specified. The spectral purity of the DFS is evaluated by analytically evaluating the output spectrum of the DFS. A novel architecture is proposed for the design of the DFS with a frequency resolution of 1/2(exp 48) of the clock frequency (0.35 mu Hz at 100 MHz), a phase resolution of 0.0056 degrees (16 bits), and a frequency spur attenuation of -96 dBc.

  16. Direct to Digital Holography

    SciTech Connect

    Bingham, P.R.; Tobin, K.W.

    2003-06-15

    In this CRADA, Oak Ridge National Laboratory (ORNL) assisted nLine Corporation of Austin, TX in the development of prototype semiconductor wafer inspection tools based on the direct-to-digital holographic (DDH) techniques invented at ORNL. Key components of this work included, development of the first prototype named the Visible Alpha Tool (VAT) that uses visible spectrum illumination of 532 nm, assist in design of second prototype tool named the DUV Alpha Tool (DAT) using deep UV (266 nm) illumination, and continuing support of nLine in the development of higher throughput commercial tools.

  17. Direct to Digital Holography

    SciTech Connect

    Bingham, P.R.; Tobin, K.W.

    2002-06-15

    In this CRADA, Oak Ridge National Laboratory (ORNL) assisted nLine Corporation of Austin, TX in the development of prototype semiconductor wafer inspection tools based on the direct-to-digital holographic (DDH) techniques invented at ORNL. Key components of this work included, testing of DDH for detection of defects in High Aspect Ratio (HAR) structures, development of image processing techniques to enhance detection capabilities through the use of both phase and intensity, and development of methods for autofocus on the DDH tools.

  18. Direct to Digital Holography

    SciTech Connect

    Bingham, P.R.; Tobin, K.W.

    2007-09-30

    In this Cooperative Research and Development Agreement (CRADA), Oak Ridge National Laboratory (ORNL) assisted nLine Corporation of Austin, TX in the development of prototype semiconductor wafer inspection tools based on the direct-to-digital holographic (DDH) techniques invented at ORNL. Key components of this work included, testing of DDH for detection of defects in High Aspect Ratio (HAR) structures, development of image processing techniques to enhance detection capabilities through the use of both phase and intensity, and development of methods for autofocus on the DDH tools.

  19. Digitally Synthesized Phased Antenna for Multibeam Global Positioning

    NASA Technical Reports Server (NTRS)

    Dunn, Charles E. (Inventor); Young, Lawrence E. (Inventor)

    2004-01-01

    In a system according to the proposed technique, the signal received by each element of the array antenna would be subjected to downconversion, and spread-spectrum demodulation and correlation as necessary; this processing would be performed separately from, and simultaneously with, similar processing of signals received by the other antenna elements. For the GPS implementation, following downconversion to baseband, the signals would be digitized, and all subsequent processing would be digital. In In the digital process, residual carriers would be removed and each signal would be correlated with a locally generated model pseudo random-noise code, all following normal GPS procedure. As part of this procedure, accumulated values would be added in software and the resulting signals would be phase-shifted in software by the amounts necessary to synthesize the desired antenna directional gain pattern of peaks and nulls. The principal advantage of this technique over the conventional radio-frequency-combining technique is that the parallel digital baseband processing of the signals from the various antenna elements would be a relatively inexpensive and flexible means for exploiting the inherent multiple-peak/multiple-null aiming capability of a phased-array antenna. In the original intended GPS application, the peaks and nulls could be directed independently for each GPS signal being tracked by the GPS receiver. This will improve the SNR simultaneously for each GPS signal being tracked while steering multiple nulls toward sources of interference. The technique could also be applied to other code-division multiple-access communication systems.

  20. Localization performance with synthesized directional audio

    NASA Astrophysics Data System (ADS)

    Agnew, Jeffrey R.; German, Valencia; Calhoun, Gloria L.; Ericson, Mark A.

    1990-07-01

    This report summarizes three studies designed to measure and compare the ability of subjects to localize sounds in azimuth, via headphones, generated by two prototype auditory localization cue synthesizers. In the first study, performance differences were found between the two synthesizers in certain areas of the azimuth plane. Additionally, the design of a synthesizer (e.g., resolution and interpolating between head-related transfer functions (HRTF's)) can impact the perceived direction of the acoustic signals. Previous research with directional audio suggests that the veridicality of 3-D auditory displays could be optimized if individualized HRTF's are employed to synthesize the virtual sound sources, particularly in elevation. However, data from this experiment suggest that this design requirement can be relaxed, especially if only azimuth information is to be conveyed by the localization synthesizer. In the second study, two response methods for measuring localization performance were evaluated. No performance differences were found when subjects either verbally reported angular estimates or pointed to a circle to indicate the perceived direction of the target stimuli. In the third study, performance was impacted by manipulating the bandwidth of the acoustic signal and head movement.

  1. Digitally synthesized phased antenna for multibeam global positioning

    NASA Technical Reports Server (NTRS)

    Dunn, Charles E. (Inventor); Young, Lawrence E. (Inventor)

    2004-01-01

    In a system according to the proposed technique (see figure), the signal received by each element of the array antenna would be subjected to downconversion, and spread-spectrum demodulation and correlation as necessary; this processing would be performed separately from, and simultaneously with, similar processing of signals received by the other antenna elements. For the GPS implementation, following downconversion to baseband, the signals would be digitized, and all subsequent processing would be digital. In the digital process, residual carriers would be removed and each signal would be correlated with a locally generated model pseudo random-noise code, all following normal GPS procedure. As part of this procedure, accumulated values would be added in software and the resulting signals would be phase-shifted in software by the amounts necessary to synthesize the desired antenna directional gain pattern of peaks and nulls. The principal advantage of this technique over the conventional radio-frequency-combining technique is that the parallel digital baseband processing of the signals from the various antenna elements would be a relatively inexpensive and flexible means for exploiting the inherent multiple-peak/multiple-null aiming capability of a phased-array antenna. In the original intended GPS application, the peaks and nulls could be directed independently for each GPS signal being tracked by the GPS receiver. This will improve the SNR simultaneously for each GPS signal being tracked while steering multiple nulls toward sources of interference. The technique could also be applied to other code-division multiple-access communication systems.

  2. Low-latency digital frequency synthesizer using the residue number system

    NASA Technical Reports Server (NTRS)

    Chren, William A., Jr.

    1993-01-01

    A low-latency frequency synthesizer using the Direct Digital Synthesis (DDS) technique has been designed. Called the Residue Assisted Frequency Synthesizer (RAFS), it exhibits frequency switching times which are reduced by more than 50 percent below previously published designs. The switching speed advantage is made possible by the use of the Residue Number System, which allows the pipeline lengths in the Phase Accumulator and other circuitry to be reduced significantly.

  3. Direct digital conversion detector technology

    NASA Astrophysics Data System (ADS)

    Mandl, William J.; Fedors, Richard

    1995-06-01

    Future imaging sensors for the aerospace and commercial video markets will depend on low cost, high speed analog-to-digital (A/D) conversion to efficiently process optical detector signals. Current A/D methods place a heavy burden on system resources, increase noise, and limit the throughput. This paper describes a unique method for incorporating A/D conversion right on the focal plane array. This concept is based on Sigma-Delta sampling, and makes optimum use of the active detector real estate. Combined with modern digital signal processors, such devices will significantly increase data rates off the focal plane. Early conversion to digital format will also decrease the signal susceptibility to noise, lowering the communications bit error rate. Computer modeling of this concept is described, along with results from several simulation runs. A potential application for direct digital conversion is also reviewed. Future uses for this technology could range from scientific instruments to remote sensors, telecommunications gear, medical diagnostic tools, and consumer products.

  4. Direct qualification of digital components

    SciTech Connect

    Lawrence, J. D., LLNL

    1998-07-08

    Existing methods for qualifying digital system software for use in safety critical systems are expensive and are based on inferences that are of doubtful validity. This report on work-in-progress describes a new approach to qualifying a class of small safety systems that can meet a number of design restrictions, where the restrictions are carefully crafted to permit safety qualification to be determined by means of static analysis of the software combined with a limited amount of testing. This approach differs from attempts to qualify unrestricted programs in the general case. Work that has been accomplished towards this goal is discussed in summary terms. The technique relies on transforming a program into a form of directed graph known as a flowgraph. Existing testing theory is used, sometimes with minor modifications, to derive a set of design restrictions that permit reasoning about safety properties of the program, based on analysis and limited testing. Future work required to complete the research is outlined.

  5. Digitally synthesized beat frequency-multiplexed fluorescence lifetime spectroscopy

    PubMed Central

    Chan, Jacky C. K.; Diebold, Eric D.; Buckley, Brandon W.; Mao, Sien; Akbari, Najva; Jalali, Bahram

    2014-01-01

    Frequency domain fluorescence lifetime imaging is a powerful technique that enables the observation of subtle changes in the molecular environment of a fluorescent probe. This technique works by measuring the phase delay between the optical emission and excitation of fluorophores as a function of modulation frequency. However, high-resolution measurements are time consuming, as the excitation modulation frequency must be swept, and faster low-resolution measurements at a single frequency are prone to large errors. Here, we present a low cost optical system for applications in real-time confocal lifetime imaging, which measures the phase vs. frequency spectrum without sweeping. Deemed Lifetime Imaging using Frequency-multiplexed Excitation (LIFE), this technique uses a digitally-synthesized radio frequency comb to drive an acousto-optic deflector, operated in a cat’s-eye configuration, to produce a single laser excitation beam modulated at multiple beat frequencies. We demonstrate simultaneous fluorescence lifetime measurements at 10 frequencies over a bandwidth of 48 MHz, enabling high speed frequency domain lifetime analysis of single- and multi-component sample mixtures. PMID:25574449

  6. Accuracy of Repetition of Digitized and Synthesized Speech for Young Children in Background Noise

    ERIC Educational Resources Information Center

    Drager, Kathryn D. R.; Clark-Serpentine, Elizabeth A.; Johnson, Kate E.; Roeser, Jennifer L.

    2006-01-01

    Purpose: The present study investigated the intelligibility of digitized and synthesized speech output in background noise for children 3-5 years old. The purpose of the study was to determine whether there was a difference in the intelligibility (ability to repeat) of 3 types of speech output (digitized, DECTalk synthesized, and MacinTalk…

  7. Accuracy of Repetition of Digitized and Synthesized Speech for Young Children in Background Noise

    ERIC Educational Resources Information Center

    Drager, Kathryn D. R.; Clark-Serpentine, Elizabeth A.; Johnson, Kate E.; Roeser, Jennifer L.

    2006-01-01

    Purpose: The present study investigated the intelligibility of digitized and synthesized speech output in background noise for children 3-5 years old. The purpose of the study was to determine whether there was a difference in the intelligibility (ability to repeat) of 3 types of speech output (digitized, DECTalk synthesized, and MacinTalk…

  8. Imaging With Synthesized 2D Mammography: Differences, Advantages, and Pitfalls Compared With Digital Mammography.

    PubMed

    Zuckerman, Samantha P; Maidment, Andrew D A; Weinstein, Susan P; McDonald, Elizabeth S; Conant, Emily F

    2017-07-01

    Synthesized 2D (s2D) mammography is rapidly replacing digital mammography in breast imaging with digital breast tomosynthesis (DBT) to reduce radiation dose and maintain screening outcomes. We illustrate variations in the appearance of s2D and digital mammograms to aid in implementation of this technology. Despite subjective differences in the appearance of s2D and digital mammograms, early outcomes of screening using s2D mammography and DBT are not inferior to those achieved with digital mammography and DBT. Understanding these variations may aid in implementing this technique and improving patient outcomes.

  9. Directions for Defense Digital Libraries.

    ERIC Educational Resources Information Center

    Larsen, Ronald L.

    1998-01-01

    Describes directions, challenges, and objectives of the information management program of the United States Defense Advanced Research Projects Agency (DARPA). The program envisions the rigor and organization normally associated with a research library to be virtually rendered and extended in the networked world of distributed information. (AEF)

  10. Directions for Defense Digital Libraries.

    ERIC Educational Resources Information Center

    Larsen, Ronald L.

    1998-01-01

    Describes directions, challenges, and objectives of the information management program of the United States Defense Advanced Research Projects Agency (DARPA). The program envisions the rigor and organization normally associated with a research library to be virtually rendered and extended in the networked world of distributed information. (AEF)

  11. Cyber Enabled Direct Digital Manufacturing

    DTIC Science & Technology

    2015-05-15

    binary file formats , it is difficult or impossible for operators and modelers to determine how a part was actually produced. Without essential process...open-access AMSF file format (Nassar and Reutzel, 2013) to enable automatic specification and extraction of processing parameters for a variety of...Using the established AMSF file format ,, the authors have developed and demonstrated two approaches for direct integration of AM processes with

  12. Full-field direct digital telemammography: preliminary

    NASA Astrophysics Data System (ADS)

    Lou, Shyhliang A.; Sickles, Edward A.; Huang, H. K.; Cao, Fei; Hoogstrate, David R.; Jahangiri, Mohammad I.

    1997-05-01

    Full-field direct digital mammography has many advantages over the conventional film/screen imaging detector. Among these are larger dynamic range, lower scattering noise, and the possibility of using it for telemammography applications to alleviate the shortage of expert mammographers. We are in the process of developing a full-field direct digital telemammography imaging chain to investigate its usefulness for telediagnosis, teleconsultation, and telemanagement. This paper describes the first phase of a three-year research program to set up a full-field direct digital mammography (FFDDM) imaging chain at the Breast Imaging Section connecting the University of California, San Francisco Medical Center and the Mt. Zion Hospital in the San Francisco Bay area. The chain consists of two FFDDM system, and two 2,500 line two-monitor workstations. An OC-3 155 Mbits/sec asynchronous transfer mode (ATM) communication network is used to connect the FFDDM and the two workstations. The FFDDM is based on a slot scan CCD detector which can image a full breast with 3,100 X 3,870 pixels, and produce a direct digital image with 50 micron pixel size. Preliminary results of the FFDDM demonstrate that it has a greater dynamic range and lower detector noise than that of a film-screen detector, and that the scattered radiation is reduced without using a grid. However, the spatial resolution is less than that of the conventional screen/film system. The 2K workstation can display simultaneously any two or four full-view mammographic images by either scrolling or subsampling on the two monitors. Display of an image takes about 1.5 seconds from the RAID disks. The ATM can transmit a 32 Mbyte digital mammogram from the FFDDM to the workstation in 3-4 seconds.

  13. Direct-to-digital holography and holovision

    DOEpatents

    Thomas, Clarence E.; Baylor, Larry R.; Hanson, Gregory R.; Rasmussen, David A.; Voelkl, Edgar; Castracane, James; Simkulet, Michelle; Clow, Lawrence

    2000-01-01

    Systems and methods for direct-to-digital holography are described. An apparatus includes a laser; a beamsplitter optically coupled to the laser; a reference beam mirror optically coupled to the beamsplitter; an object optically coupled to the beamsplitter, a focusing lens optically coupled to both the reference beam mirror and the object; and a digital recorder optically coupled to the focusing lens. A reference beam is incident upon the reference beam mirror at a non-normal angle, and the reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form an image. The systems and methods provide advantages in that computer assisted holographic measurements can be made.

  14. Image rejects in general direct digital radiography

    PubMed Central

    Rosanowsky, Tine Blomberg; Jensen, Camilla; Wah, Kenneth Hong Ching

    2015-01-01

    Background The number of rejected images is an indicator of image quality and unnecessary imaging at a radiology department. Image reject analysis was frequent in the film era, but comparably few and small studies have been published after converting to digital radiography. One reason may be a belief that rejects have been eliminated with digitalization. Purpose To measure the extension of deleted images in direct digital radiography (DR), in order to assess the rates of rejects and unnecessary imaging and to analyze reasons for deletions, in order to improve the radiological services. Material and Methods All exposed images at two direct digital laboratories at a hospital in Norway were reviewed in January 2014. Type of examination, number of exposed images, and number of deleted images were registered. Each deleted image was analyzed separately and the reason for deleting the image was recorded. Results Out of 5417 exposed images, 596 were deleted, giving a deletion rate of 11%. A total of 51.3% were deleted due to positioning errors and 31.0% due to error in centering. The examinations with the highest percentage of deleted images were the knee, hip, and ankle, 20.6%, 18.5%, and 13.8% respectively. Conclusion The reject rate is at least as high as the deletion rate and is comparable with previous film-based imaging systems. The reasons for rejection are quite different in digital systems. This falsifies the hypothesis that digitalization would eliminates rejects. A deleted image does not contribute to diagnostics, and therefore is an unnecessary image. Hence, the high rates of deleted images have implications for management, training, education, as well as for quality. PMID:26500784

  15. Image rejects in general direct digital radiography.

    PubMed

    Hofmann, Bjørn; Rosanowsky, Tine Blomberg; Jensen, Camilla; Wah, Kenneth Hong Ching

    2015-10-01

    The number of rejected images is an indicator of image quality and unnecessary imaging at a radiology department. Image reject analysis was frequent in the film era, but comparably few and small studies have been published after converting to digital radiography. One reason may be a belief that rejects have been eliminated with digitalization. To measure the extension of deleted images in direct digital radiography (DR), in order to assess the rates of rejects and unnecessary imaging and to analyze reasons for deletions, in order to improve the radiological services. All exposed images at two direct digital laboratories at a hospital in Norway were reviewed in January 2014. Type of examination, number of exposed images, and number of deleted images were registered. Each deleted image was analyzed separately and the reason for deleting the image was recorded. Out of 5417 exposed images, 596 were deleted, giving a deletion rate of 11%. A total of 51.3% were deleted due to positioning errors and 31.0% due to error in centering. The examinations with the highest percentage of deleted images were the knee, hip, and ankle, 20.6%, 18.5%, and 13.8% respectively. The reject rate is at least as high as the deletion rate and is comparable with previous film-based imaging systems. The reasons for rejection are quite different in digital systems. This falsifies the hypothesis that digitalization would eliminates rejects. A deleted image does not contribute to diagnostics, and therefore is an unnecessary image. Hence, the high rates of deleted images have implications for management, training, education, as well as for quality.

  16. Reconfigurable firmware-defined radios synthesized from standard digital logic cells

    NASA Astrophysics Data System (ADS)

    Faisal, Muhammad; Park, Youngmin; Wentzloff, David D.

    2011-06-01

    This paper presents recent work on reconfigurable all-digital radio architectures. We leverage the flexibility and scalability of synthesized digital cells to construct reconfigurable radio architectures that consume significantly less power than a software defined radio implementing similar architectures. We present two prototypes of such architectures that can receive and demodulate FM and FRS band signals. Moreover, a radio architecture based on a reconfigurable alldigital phase-locked loop for coherent demodulation is presented.

  17. Reject analysis in direct digital radiography.

    PubMed

    Andersen, Eivind Richter; Jorde, Jannike; Taoussi, Nadia; Yaqoob, Sadia Halima; Konst, Bente; Seierstad, Therese

    2012-03-01

    Reject analysis can be used as a quality indicator, and is an important tool in localizing areas where optimization is required. Reducing number of rejects is important yielding reduced patient exposure and increased cost-effectiveness. To determine rejection rates and causes in direct digital radiography. Data were collected during a three-month period in spring 2010 at two direct digital laboratories in Norway. All X-ray examinations, types, numbers, and reasons for rejections were obtained using automatic reject analysis software. Thirteen causes for rejection could be selected. Out of the 27,284 acquired images, 3206 were rejected, yielding an overall rejection rate of 12%. Highest rejection rates were found for examination of knees, shoulders, and wrist. In all, 77% of the rejected images arose from positioning errors. An overall rejection rate of 12% indicates a need for optimizing radiographic practice in the department.

  18. Spur Correlation in an Array of Direct Digital Synthesizers

    DTIC Science & Technology

    2010-11-01

    Audio and Electroacoustics, AU-19, 48-57. [5] K. Lauritzen, DDS Block Diagram, private communication, March 2010. [6] K. Lauritzen, E. Richards, S...8] S. Cheng, J. R. Jensen, R. E. Wallis , and G. L. Weaver, 2004, “Further enhancements to the analysis of spectral purity in the application of

  19. Polaroid Graphics Imaging Direct Digital Color Proofing

    NASA Astrophysics Data System (ADS)

    King, Patrick F.

    1989-04-01

    Good morning ladies and gentlemen. I represent Polaroid Graphics Imaging, a wholly owned subsidiary of the Polaroid Corporation. We wish to thank Ken Cloud and the SPIE for the opportunity to speak today. Several criterion are fundamental in the role for Direct Digital Color Proofing (DDCP), First, the DDCP must represent a first generation hardcopy of the exact color information in the production stream. If must, as it's name suggests be an exact, proof (hence the name direct) of the electronic or digital information which would otherwise be directed toward film working. It is after all the most critical means to evaluate the quality of whatever pagination, scanner or color work which has gone be for it. Second, the DDCP must represent an opportunity. That opportunity is to reconvene the production stream and move to film making, optical or magnetic storage, or satellite transmission with the confidence that the DDCP is identical to some conventional counterpart. In the case of film it must match a conventional proof and press sheet, dot for dot. Otherwise it is merely an exercise in interpretation. For magnetic or optical storage and satellite transmission there must be assurance that at any opportunity either a duplicate DDCP or a conventional film/proof could reproduce earlier results. Finally as the printed product is the final goal and direct to press is evolving in direct to plate and direct to gravure printing the DDCP must share the half toner lineage of these products. Thirdly and hardly least, the whole purpose for DDCP is increased productivity. However, our industry struggles to maintain individuality and variety. Somehow DDCP must balance these forces.

  20. Personalized direct marketing using digital publishing

    NASA Astrophysics Data System (ADS)

    Kutty, Cheeniyil L.; Prabhakaran, Jayasree K.

    2006-02-01

    In today's cost-conscious business climate, marketing and customer service decision makers are increasingly concerned with how to increase customer response and retention rates. Companies spend large amounts of money on Customer Relationship Management (CRM) solutions and data acquisition but they don't know how to use the information stored in these systems to improve the effectiveness of their direct marketing campaigns. By leveraging the customer information they already have, companies can create personalized, printed direct mail programs that generate high response rates, greater returns, and stronger customer loyalty, while gaining a significant edge over their competitors. To reach the promised land of one-to-one direct marketing (personalized direct marketing - PDM), companies need an end-to-end solution for creating, managing, printing, and distributing personalized direct mail "on demand." Having access to digital printing is just one piece of the solution. A more complete approach includes leveraging personalization technology into a useful direct marketing tool that provides true one-to-one marketing, allowing variable images and text in a personalized direct mail. This paper discusses integration of CRM with a Print-on-Demand solution so as to create truly personalized printed marketing campaigns for one or many individuals based on the profile information, preferences and purchase history stored in the CRM.

  1. Direct visualization of identified and newly synthesized proteins in situ

    PubMed Central

    Dieck, Susanne tom; Kochen, Lisa; Hanus, Cyril; Bartnik, Ina; Nassim-Assir, Belquis; Merk, Katrin; Mosler, Thorsten; Garg, Sakshi; Bunse, Stefanie; Tirrell, David A.; Schuman, Erin M.

    2015-01-01

    Protein synthesis is a dynamic process to tune the cellular proteome to internal and external demands. Metabolic labeling approaches identify the general proteomic response but missing is a tool to visualize within cells specific newly synthesized proteins. Here we describe a technique that couples non-canonical amino acid tagging or puromycylation with the proximity-ligation assay to visualize identified newly synthesized proteins and monitor their origin, redistribution and turnover in situ. PMID:25775042

  2. Spatio-temporal scanning modality for synthesizing interferograms and digital holograms.

    PubMed

    Bianco, V; Paturzo, M; Ferraro, P

    2014-09-22

    We investigate the spatio-temporal scanning of a single-pixel row for building up synthetic interferograms or digital holograms, shifted each other of a desired phase step. This unusual recording modality exploits the object movement to synthesize interferograms with extended Field of View and improved noise contrast. We report the theoretical formulation of the synthetizing recording process and experimental evidence of various cases demonstrating quantitative phase retrieval by adopting this intrinsic phase-shifting procedure. The proposed method could be particularly suited in all cases where the object shift is an intrinsic feature of the investigated system, as e.g. in microfluidics imaging.

  3. Direct phasing from Patterson syntheses by δ recycling.

    PubMed

    Rius, Jordi

    2012-01-01

    The direct methods origin-free modulus sum function [Rius (1993). Acta Cryst. A49, 406-409] includes in its definition the structure factor G(Φ) of the squared crystal structure expressed in terms of Φ, the set of φ phases of the normalized structure factors E's of the crystal structure of unit-cell volume V. Here the simpler sum function variant S'(P) = ∑(H)E(-H)∫(V)δ(P,Δ)(Φ)exp(i2πHr)dV extended over all H reflections is introduced which involves no G's and in which the δ(P,Δ) function corresponds to δ(P) = FT(-1){(E(2)(H) - )exp[iφ(H)(Φ)]} (where FT = Fourier transform) with all values smaller than Δ = 2.5σ(P) equated to zero (σ(2)(P) is the variance of δ(P) calculable from the experimental intensities). The new phase estimates are obtained by Fourier transforming δ(P,Δ). This iterative phasing method (δ recycling) only requires calculation of Fourier transforms at two stages. Since δ(M) ≃ δ(P)/2, similar arguments are valid for δ(M) = FT(-1)[(E(H) - )exp(iφ(H))] from which the corresponding S'(M) phasing function follows.

  4. Direct Digital Control Liquid Level Experiment.

    ERIC Educational Resources Information Center

    Adb-El-Bary, M. F.

    1983-01-01

    Describes an experiment to give students exposure to digital control widely used in industry but not given much attention in most undergraduate process control curricula. Students write their own control programs and experimentally determine the transfer functions for all system components. Also describes experimental apparatus used in the…

  5. Estimation of Laminar Burning Velocities by Direct Digital Photography

    ERIC Educational Resources Information Center

    Uske, J.; Barat, R.

    2004-01-01

    The Bunsen burner flame, which is the most common flame in the laboratory, can be easily studied for its dynamics because of modern, economical digital technology available to student laboratories. Direct digital photography of Bunsen flames is used to obtain laminar burning velocities of selected gaseous hydrocarbon/air flames.

  6. Estimation of Laminar Burning Velocities by Direct Digital Photography

    ERIC Educational Resources Information Center

    Uske, J.; Barat, R.

    2004-01-01

    The Bunsen burner flame, which is the most common flame in the laboratory, can be easily studied for its dynamics because of modern, economical digital technology available to student laboratories. Direct digital photography of Bunsen flames is used to obtain laminar burning velocities of selected gaseous hydrocarbon/air flames.

  7. Digital sound service for direct broadcasting satellites

    NASA Astrophysics Data System (ADS)

    Treytl, D.

    A 16 channel (4 phase (CPSK), or 12 channel (2 phase CPSK) digital sound link for the TV Sat satellite is proposed. Small parabolic antennas suitable for sound and TV broadcasts assure reception. A specially developed tuner allows the user to select either a given program from 1 of 16, or 1 of 8 types of program, e.g., sport or opera. Tests with OTS satellite and a cable distribution network prove the feasibility of the proposal. Encoding, transmission, signal modulation and links are outlined. Equipment is described.

  8. Digit Ratio Predicts Sense of Direction in Women

    PubMed Central

    Chai, Xiaoqian J.; Jacobs, Lucia F.

    2012-01-01

    The relative length of the second-to-fourth digits (2D:4D) has been linked with prenatal androgen in humans. The 2D:4D is sexually dimorphic, with lower values in males than females, and appears to correlate with diverse measures of behavior. However, the relationship between digit ratio and cognition, and spatial cognition in particular, has produced mixed results. In the present study, we hypothesized that spatial tasks separating cue conditions that either favored female or male strategies would examine this structure-function correlation with greater precision. Previous work suggests that males are better in the use of directional cues than females. In the present study, participants learned a target location in a virtual landscape environment, in conditions that contained either all directional (i.e., distant or compass bearing) cues, or all positional (i.e., local, small objects) cues. After a short delay, participants navigated back to the target location from a novel starting location. Males had higher accuracy in initial search direction than females in environments with all directional cues. Lower digit ratio was correlated with higher accuracy of initial search direction in females in environments with all directional cues. Mental rotation scores did not correlate with digit ratio in either males or females. These results demonstrate for the first time that a sex difference in the use of directional cues, i.e., the sense of direction, is associated with more male-like digit ratio. PMID:22393451

  9. Clinical implementation of synthesized mammography with digital breast tomosynthesis in a routine clinical practice.

    PubMed

    Freer, Phoebe E; Riegert, Joanna; Eisenmenger, Laura; Ose, Dominik; Winkler, Nicole; Stein, Matthew A; Stoddard, Gregory J; Hess, Rachel

    2017-08-05

    Most published studies evaluating digital breast tomosynthesis (DBT) included a separate 2-dimensional full-field digital mammogram (FFDM) for DBT screening protocols, increasing radiation from screening mammography. Synthesized mammography (SM) creates a 2-dimensional image from the DBT source data, and if used in place of FFDM, it reduces radiation of DBT screening. This study evaluated the implementation of SM + DBT in routine screening practice in terms of recall rates, cancer detection rates (CDR), % of minimal cancers, % of node-positive cancers, and positive predictive values (PPV). A multivariate retrospective institutional analysis was performed on 31,979 women who obtained screening mammography (10/2013-12/2015) with cohorts divided by modality (SM + DBT, FFDM + DBT, and FFDM). We adjusted for comparison mammograms, age, breast density, and the interpreting radiologist. Recall type was analyzed for differences (focal asymmetry, asymmetry, masses, calcifications, architectural distortion). SM + DBT significantly decreased the recall rate compared to FFDM (5.52 vs. 7.83%, p < 0.001) with no differences in overall CDR (p = 0.66), invasive and/or in situ CDR, or percentages of minimal and node-negative cancers. PPV1 significantly increased with SM + DBT relative to FFDM (9.1 vs. 6.2%, p = 0.02). SM + DBT did not differ significantly in recall rate or overall CDR compared to FFDM + DBT. There were statistically significant differences in certain findings recalled by screening modality (e.g., focal asymmetries). SM + DBT reduces false positives compared to FFDM, while maintaining the CDR and other desirable audit outcome data. SM + DBT is more accurate than FFDM alone, and is a desirable alternative to FFDM + DBT, given the added benefit of radiation reduction.

  10. Direct digital RF synthesis and modulation for MSAT mobile applications

    NASA Technical Reports Server (NTRS)

    Crozier, Stewart; Datta, Ravi; Sydor, John

    1993-01-01

    A practical method of performing direct digital RF synthesis using the Hilbert transform single sideband (SSB) technique is described. It is also shown that amplitude and phase modulation can be achieved directly at L-band with frequency stability and spurii performance exceeding stringent MSAT system requirements.

  11. Synthesized femtosecond laser pulse source for two-wavelength contouring with simultaneously recorded digital holograms.

    PubMed

    Hansel, Thomas; Steinmeyer, Günter; Grunwald, Ruediger; Falldorf, Claas; Bonitz, Jens; Kaufmann, Christian; Kebbel, Volker; Griebner, Uwe

    2009-02-16

    A dual-wavelength femtosecond laser pulse source and its application for digital holographic single-shot contouring are presented. The synthesized laser source combines sub-picosecond time scales with a wide reconstruction range. A center wavelength distance of the two separated pulses of only 15 nm with a high contrast was demonstrated by spectral shaping of the 50 nm broad seed spectrum centered at 800 nm. Owing to the resulting synthetic wavelength, the scan depth range without phase ambiguity is extended to the 100-microm-range. Single-shot dual-wavelength imaging is achieved by using two CMOS cameras in a Twyman-Green interferometer, which is extended by a polarization encoding sequence to separate the holograms. The principle of the method is revealed, and experimental results concerning a single axis scanner mirror operating at a resonance frequency of 0.5 kHz are presented. Within the synthetic wavelength, the phase difference information of the object was unambiguously retrieved and the 3D-shape calculated. To the best of our knowledge, this is the first time that single-shot two-wavelength contouring on a sub-ps time scale is reported.

  12. Commercial Off the Shelf Direct Digital Synthesizers for Digital Array Radar

    DTIC Science & Technology

    2005-12-01

    AD8346 which is spec at -13 dBm RFout = awgn(P_dBm,-10); % add white gaussian noise % Convert time scale to frequency scale delf =1/max(t); Nf...length(VoutSpec)-1; f=[0:Nf]* delf ; % Plot figures figure(1),subplot(221); % plot I signal vs time plot(t/1e-6...at -13 dBm 55 RFout = awgn(P_dBm,-5); % add white gaussian noise % Convert time scale to frequency scale delf =1/max(t); Nf=length(VoutSpec/2

  13. Reorienting Self-Directed Learning for the Creative Digital Era

    ERIC Educational Resources Information Center

    Karakas, Fahri; Manisaligil, Alperen

    2012-01-01

    Purpose: The purpose of this paper is to identify the new role that human resource developers play in the globally connected workplace. Towards that end, this paper explores the changing landscape of self-directed learning (SDL) within the digital ecosystem based on the concept of World 2.0. Design/methodology/approach: This paper reviews and…

  14. Reorienting Self-Directed Learning for the Creative Digital Era

    ERIC Educational Resources Information Center

    Karakas, Fahri; Manisaligil, Alperen

    2012-01-01

    Purpose: The purpose of this paper is to identify the new role that human resource developers play in the globally connected workplace. Towards that end, this paper explores the changing landscape of self-directed learning (SDL) within the digital ecosystem based on the concept of World 2.0. Design/methodology/approach: This paper reviews and…

  15. Effective dose from direct and indirect digital panoramic units.

    PubMed

    Lee, Gun-Sun; Kim, Jin-Soo; Seo, Yo-Seob; Kim, Jae-Duk

    2013-06-01

    This study aimed to provide comparative measurements of the effective dose from direct and indirect digital panoramic units according to phantoms and exposure parameters. Dose measurements were carried out using a head phantom representing an average man (175 cm tall, 73.5 kg male) and a limbless whole body phantom representing an average woman (155 cm tall, 50 kg female). Lithium fluoride thermoluminescent dosimeter (TLD) chips were used for the dosimeter. Two direct and 2 indirect digital panoramic units were evaluated in this study. Effective doses were derived using 2007 International Commission on Radiological Protection (ICRP) recommendations. The effective doses of the 4 digital panoramic units ranged between 8.9 µSv and 37.8 µSv. By using the head phantom, the effective doses from the direct digital panoramic units (37.8 µSv, 27.6 µSv) were higher than those from the indirect units (8.9 µSv, 15.9 µSv). The same panoramic unit showed the difference in effective doses according to the gender of the phantom, numbers and locations of TLDs, and kVp. To reasonably assess the radiation risk from various dental radiographic units, the effective doses should be obtained with the same numbers and locations of TLDs, and with standard hospital exposure. After that, it is necessary to survey the effective doses from various dental radiographic units according to the gender with the corresponding phantom.

  16. Effective dose from direct and indirect digital panoramic units

    PubMed Central

    Lee, Gun-Sun; Kim, Jin-Soo; Seo, Yo-Seob

    2013-01-01

    Purpose This study aimed to provide comparative measurements of the effective dose from direct and indirect digital panoramic units according to phantoms and exposure parameters. Materials and Methods Dose measurements were carried out using a head phantom representing an average man (175 cm tall, 73.5 kg male) and a limbless whole body phantom representing an average woman (155 cm tall, 50 kg female). Lithium fluoride thermoluminescent dosimeter (TLD) chips were used for the dosimeter. Two direct and 2 indirect digital panoramic units were evaluated in this study. Effective doses were derived using 2007 International Commission on Radiological Protection (ICRP) recommendations. Results The effective doses of the 4 digital panoramic units ranged between 8.9 µSv and 37.8 µSv. By using the head phantom, the effective doses from the direct digital panoramic units (37.8 µSv, 27.6 µSv) were higher than those from the indirect units (8.9 µSv, 15.9 µSv). The same panoramic unit showed the difference in effective doses according to the gender of the phantom, numbers and locations of TLDs, and kVp. Conclusion To reasonably assess the radiation risk from various dental radiographic units, the effective doses should be obtained with the same numbers and locations of TLDs, and with standard hospital exposure. After that, it is necessary to survey the effective doses from various dental radiographic units according to the gender with the corresponding phantom. PMID:23807930

  17. Direct drive digital servo press with high parallel control

    NASA Astrophysics Data System (ADS)

    Murata, Chikara; Yabe, Jun; Endou, Junichi; Hasegawa, Kiyoshi

    2013-12-01

    Direct drive digital servo press has been developed as the university-industry joint research and development since 1998. On the basis of this result, 4-axes direct drive digital servo press has been developed and in the market on April of 2002. This servo press is composed of 1 slide supported by 4 ball screws and each axis has linearscale measuring the position of each axis with high accuracy less than μm order level. Each axis is controlled independently by servo motor and feedback system. This system can keep high level parallelism and high accuracy even with high eccentric load. Furthermore the 'full stroke full power' is obtained by using ball screws. Using these features, new various types of press forming and stamping have been obtained by development and production. The new stamping and forming methods are introduced and 'manufacturing' need strategy of press forming with high added value and also the future direction of press forming are also introduced.

  18. Feasibility of direct digital sampling for diffuse optical frequency domain spectroscopy in tissue

    NASA Astrophysics Data System (ADS)

    Roblyer, Darren; O'Sullivan, Thomas D.; Warren, Robert V.; Tromberg, Bruce J.

    2013-04-01

    Frequency domain optical spectroscopy in the diffusive regime is currently being investigated for biomedical applications including tumor detection, therapy monitoring, exercise metabolism and others. Analog homodyne or heterodyne detection of sinusoidally modulated signals has been the predominant method for measuring phase and amplitude of photon density waves that have traversed through tissue. Here we demonstrate the feasibility of utilizing direct digital sampling of modulated signals using a 3.6 gigasample/second 12 bit analog to digital converter. Digitally synthesized modulated signals between 50 MHz and 400 MHz were measured on tissue-simulating phantoms at six near-infrared wavelengths. An amplitude and phase precision of 1% and 0.6° were achieved during drift tests. Amplitude, phase, scattering and absorption values were compared with a well-characterized network analyzer-based diffuse optical device. Optical properties measured with both systems were within 3.6% for absorption and 2.8% for scattering over a range of biologically relevant values. Direct digital sampling represents a viable method for frequency domain diffuse optical spectroscopy and has the potential to reduce system complexity, size and cost.

  19. Feasibility of Direct Digital Sampling for Diffuse Optical Frequency Domain Spectroscopy in Tissue.

    PubMed

    Roblyer, Darren; O'Sullivan, Thomas D; Warren, Robert V; Tromberg, Bruce

    2013-04-01

    Frequency domain optical spectroscopy in the diffusive regime is currently being investigated for biomedical applications including tumor detection, therapy monitoring, exercise metabolism, and others. Analog homodyne or heterodyne detection of sinusoidally modulated signals have been the predominant method for measuring phase and amplitude of photon density waves that have traversed through tissue. Here we demonstrate the feasibility of utilizing direct digital sampling of modulated signals using a 3.6 Gigasample/second 12 bit Analog to Digital Converter. Digitally synthesized modulated signals between 50MHz and 400MHz were measured on tissue simulating phantoms at six near-infrared wavelengths. An amplitude and phase precision of 1% and 0.6 degrees were achieved during drift tests. Amplitude, phase, scattering and absorption values were compared with a well-characterized network analyzer based diffuse optical device. Measured optical properties measured with both systems were within 3.6% for absorption and 2.8% for scattering over a range of biologically relevant values. Direct digital sampling represents a viable method for frequency domain diffuse optical spectroscopy and has the potential to reduce system complexity, size, and cost.

  20. AN INVESTIGATION OF A DIGITAL BEARING COMPUTER FOR A SMALL APERATURE RADIO DIRECTION FINDING SYSTEM.

    DTIC Science & Technology

    DIRECTION FINDING , RADIO EQUIPMENT), (*RADIO EQUIPMENT, DIRECTION FINDING ), (*DIGITAL COMPUTERS, NAVIGATION COMPUTERS), (*NAVIGATION COMPUTERS... DIRECTION FINDING ), RADIO WAVES, ANGLE OF ARRIVAL, RADIOFREQUENCY POWER, MULTIPATH TRANSMISSION, PHASE MEASUREMENT

  1. Off-axis illumination direct-to-digital holography

    DOEpatents

    Thomas, Clarence E.; Price, Jeffery R.; Voelkl, Edgar; Hanson, Gregory R.

    2004-06-08

    Systems and methods are described for off-axis illumination direct-to-digital holography. A method of recording an off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis, includes: reflecting a reference beam from a reference mirror at a non-normal angle; reflecting an object beam from an object at an angle with respect to an optical axis defined by a focusing lens; focusing the reference beam and the object beam at a focal plane of a digital recorder to form the off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; digitally recording the off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; Fourier analyzing the recorded off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes by transforming axes of the recorded off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes in Fourier space to sit on top of a heterodyne carrier frequency defined as an angle between the reference beam and the object beam; applying a digital filter to cut off signals around an original origin; and then performing an inverse Fourier transform.

  2. Recording multiple spatially-heterodyned direct to digital holograms in one digital image

    DOEpatents

    Hanson, Gregory R [Clinton, TN; Bingham, Philip R [Knoxville, TN

    2008-03-25

    Systems and methods are described for recording multiple spatially-heterodyned direct to digital holograms in one digital image. A method includes digitally recording, at a first reference beam-object beam angle, a first spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; Fourier analyzing the recorded first spatially-heterodyned hologram by shifting a first original origin of the recorded first spatially-heterodyned hologram to sit on top of a first spatial-heterodyne carrier frequency defined by the first reference beam-object beam angle; digitally recording, at a second reference beam-object beam angle, a second spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; Fourier analyzing the recorded second spatially-heterodyned hologram by shifting a second original origin of the recorded second spatially-heterodyned hologram to sit on top of a second spatial-heterodyne carrier frequency defined by the second reference beam-object beam angle; applying a first digital filter to cut off signals around the first original origin and define a first result; performing a first inverse Fourier transform on the first result; applying a second digital filter to cut off signals around the second original origin and define a second result; and performing a second inverse Fourier transform on the second result, wherein the first reference beam-object beam angle is not equal to the second reference beam-object beam angle and a single digital image includes both the first spatially-heterodyned hologram and the second spatially-heterodyned hologram.

  3. Implementation of Synthesized Two-dimensional Mammography in a Population-based Digital Breast Tomosynthesis Screening Program.

    PubMed

    Zuckerman, Samantha P; Conant, Emily F; Keller, Brad M; Maidment, Andrew D A; Barufaldi, Bruno; Weinstein, Susan P; Synnestvedt, Marie; McDonald, Elizabeth S

    2016-12-01

    Purpose To evaluate the early implementation of synthesized two-dimensional (s2D) mammography in a population screened entirely with s2D and digital breast tomosynthesis (DBT) (referred to as s2D/DBT) and compare recall rates and cancer detection rates to historic outcomes of digital mammography combined with DBT (referred to as digital mammography/DBT) screening. Materials and Methods This was an institutional review board-approved and HIPAA-compliant retrospective interpretation of prospectively acquired data with waiver of informed consent. Compared were recall rates, biopsy rates, cancer detection rates, and radiation dose for 15 571 women screened with digital mammography/DBT from October 1, 2011, to February 28, 2013, and 5366 women screened with s2D/DBT from January 7, 2015, to June 30, 2015. Two-sample z tests of equal proportions were used to determine statistical significance. Results Recall rate for s2D/DBT versus digital mammography/DBT was 7.1% versus 8.8%, respectively (P < .001). Biopsy rate for s2D/DBT versus digital mammography/DBT decreased (1.3% vs 2.0%, respectively; P = .001). There was no significant difference in cancer detection rate for s2D/DBT versus digital mammography/DBT (5.03 of 1000 vs 5.45 of 1000, respectively; P = .72). The average glandular dose was 39% lower in s2D/DBT versus digital mammography/DBT (4.88 mGy vs 7.97 mGy, respectively; P < .001). Conclusion Screening with s2D/DBT in a large urban practice resulted in similar outcomes compared with digital mammography/DBT imaging. Screening with s2D/DBT allowed for the benefits of DBT with a decrease in radiation dose compared with digital mammography/DBT. (©) RSNA, 2016 An earlier incorrect version of this article appeared online. This article was corrected on August 11, 2016.

  4. A direct digital synthesis chirped pulse Fourier transform microwave spectrometer.

    PubMed

    Finneran, Ian A; Holland, Daniel B; Carroll, P Brandon; Blake, Geoffrey A

    2013-08-01

    Chirped pulse Fourier transform microwave (CP-FTMW) spectrometers have become the instrument of choice for acquiring rotational spectra, due to their high sensitivity, fast acquisition rate, and large bandwidth. Here we present the design and capabilities of a recently constructed CP-FTMW spectrometer using direct digital synthesis (DDS) as a new method for chirped pulse generation, through both a suite of extensive microwave characterizations and deep averaging of the 10-14 GHz spectrum of jet-cooled acetone. The use of DDS is more suited for in situ applications of CP-FTMW spectroscopy, as it reduces the size, weight, and power consumption of the chirp generation segment of the spectrometer all by more than an order of magnitude, while matching the performance of traditional designs. The performance of the instrument was further improved by the use of a high speed digitizer with dedicated signal averaging electronics, which facilitates a data acquisition rate of 2.1 kHz.

  5. Possible applications of atomic frequency standards with an internal high resolution digital synthesizer

    NASA Technical Reports Server (NTRS)

    Detoma, E.; Stern, A.

    1993-01-01

    The applications of Atomic Frequency Standards with an internal synthesizer (thereafter referred as 'Synthesized Frequency Standards or Oscillators') with a special emphasis on the Rb oscillator are reviewed. A fractional frequency synthesizer, developed by SEPA, was incorporated in the Frequency Locked Loop of a TFL Rubidium Frequency Standard. This combination allows a frequency settability in steps of 1.5 x 10(exp -12) (optional 1 x 10(exp -13) over a range of 6 x 10(exp -9) without having to resort to change the C-field to tune the output frequency of the device. This capability, coupled to the excellent short term stability of the Rb frequency standard, opens new possibilities for time and frequency users in the various fields (time metrology, navigation, communication, etc.) in which stable frequency standards find their application.

  6. Possible applications of atomic frequency standards with an internal high resolution digital synthesizer

    NASA Technical Reports Server (NTRS)

    Detoma, E.; Stern, A.

    1993-01-01

    The applications of Atomic Frequency Standards with an internal synthesizer (thereafter referred as 'Synthesized Frequency Standards or Oscillators') with a special emphasis on the Rb oscillator are reviewed. A fractional frequency synthesizer, developed by SEPA, was incorporated in the Frequency Locked Loop of a TFL Rubidium Frequency Standard. This combination allows a frequency settability in steps of 1.5 x 10(exp -12) (optional 1 x 10(exp -13) over a range of 6 x 10(exp -9) without having to resort to change the C-field to tune the output frequency of the device. This capability, coupled to the excellent short term stability of the Rb frequency standard, opens new possibilities for time and frequency users in the various fields (time metrology, navigation, communication, etc.) in which stable frequency standards find their application.

  7. Thermal Modeling of Direct Digital Melt-Deposition Processes

    NASA Astrophysics Data System (ADS)

    Cooper, K. P.; Lambrakos, S. G.

    2011-02-01

    Additive manufacturing involves creating three-dimensional (3D) objects by depositing materials layer-by-layer. The freeform nature of the method permits the production of components with complex geometry. Deposition processes provide one more capability, which is the addition of multiple materials in a discrete manner to create "heterogeneous" objects with locally controlled composition and microstructure. The result is direct digital manufacturing (DDM) by which dissimilar materials are added voxel-by-voxel (a voxel is volumetric pixel) following a predetermined tool-path. A typical example is functionally gradient material such as a gear with a tough core and a wear-resistant surface. The inherent complexity of DDM processes is such that process modeling based on direct physics-based theory is difficult, especially due to a lack of temperature-dependent thermophysical properties and particularly when dealing with melt-deposition processes. In order to overcome this difficulty, an inverse problem approach is proposed for the development of thermal models that can represent multi-material, direct digital melt deposition. This approach is based on the construction of a numerical-algorithmic framework for modeling anisotropic diffusivity such as that which would occur during energy deposition within a heterogeneous workpiece. This framework consists of path-weighted integral formulations of heat diffusion according to spatial variations in material composition and requires consideration of parameter sensitivity issues.

  8. EBSD characterization of the growth mechanism of SiC synthesized via direct microwave heating

    SciTech Connect

    Wang, Jigang; Huang, Shan; Liu, Song; Qing, Zhou

    2016-04-15

    Well-crystallized 3C-silicon carbide (SiC) grains/nanowires have been synthesized rapidly and conveniently via direct microwave heating, simply using silicon dioxide powders and artificial graphite as raw materials. The comprehensive characterizations have been employed to investigate the micro-structure of the obtained 3C-SiC products. Results indicated that, different from the classic screw dislocation growth mechanism, the 3C-SiC grains/nanowires synthesized via high-energy vacuum microwave irradiation were achieved through the two-dimension nucleation and laminar growth mechanism. Especially, the electron backscattered diffraction (EBSD) was employed to characterize the crystal planes of the as-grown SiC products. The calculated Euler angles suggested that the fastest-growing crystal planes (211) were overlapped gradually. Through the formation of the (421) transformation plane, (211) finally evolved to (220) which existed as the side face of SiC grains. The most stable crystal planes (111) became the regular hexagonal planes in the end, which could be explained by the Bravais rule. The characterization results of EBSD provided important experimental information for the evolution of crystal planes. - Graphical abstract: The formation of 3C-SiC prepared via direct microwave heating follows the mechanism of two-dimension nucleation and laminar growth. - Highlights: • 3C−SiC grains/nanowires were obtained via direct microwave heating. • 3C−SiC followed the mechanism of two-dimension nucleation and laminar growth. • In-situ EBSD analysis provided the experimental evidences of the growth.

  9. An interface-directed coassembly approach to synthesize uniform large-pore mesoporous silica spheres.

    PubMed

    Wang, Minghong; Sun, Zhenkun; Yue, Qin; Yang, Jie; Wang, Xiqing; Deng, Yonghui; Yu, Chengzhong; Zhao, Dongyuan

    2014-02-05

    A facile and controllable interface-directed coassembly (IDCA) approach is developed for the first time to synthesize uniform discrete mesoporous silica particles with a large pore size (ca. 8 nm) by using 3-dimensional macroporous carbon (3DOMC) as the nanoreactor for the confined coassembly of template molecules and silica source. By controlling the amount of the precursor solution and using Pluronic templates with different compositions, we can synthesize mesoporous silica particles with diverse morphologies (spheres, hollow spheres, and hemispheres) and different mesostructure (e.g., 2-D hexagonal and 3D face centered cubic symmetry), high surface area of about 790 m(2)/g, and large pore volume (0.98 cm(3)/g). The particle size can be tunable from submicrometer to micrometer regimes by changing the macropore diameter of 3DOMC. Importantly, this synthesis concept can be extended to fabricate multifunctional mesoporous composite spheres with a magnetic core and a mesoporous silica shell, large saturated magnetization (23.5 emu/g), and high surface area (280 m(2)/g). With the use of the magnetic mesoporous silica spheres as a magnetically recyclable absorbent, a fast and efficient removal of microcystin from water is achieved, and they can be recycled for 10 times without a significant decrease of removal efficiency for microcystin.

  10. Digitally synthesized high purity, high-voltage radio frequency drive electronics for mass spectrometry

    SciTech Connect

    Schaefer, R. T.; Mojarradi, M.; MacAskill, J. A.; Chutjian, A.; Darrach, M. R.; Madzunkov, S. M.; Shortt, B. J.

    2008-09-15

    Reported herein is development of a quadrupole mass spectrometer controller (MSC) with integrated radio frequency (rf) power supply and mass spectrometer drive electronics. Advances have been made in terms of the physical size and power consumption of the MSC, while simultaneously making improvements in frequency stability, total harmonic distortion, and spectral purity. The rf power supply portion of the MSC is based on a series-resonant LC tank, where the capacitive load is the mass spectrometer itself, and the inductor is a solenoid or toroid, with various core materials. The MSC drive electronics is based on a field programmable gate array (FPGA), with serial peripheral interface for analog-to-digital and digital-to-analog converter support, and RS232/RS422 communications interfaces. The MSC offers spectral quality comparable to, or exceeding, that of conventional rf power supplies used in commercially available mass spectrometers; and as well an inherent flexibility, via the FPGA implementation, for a variety of tasks that includes proportional-integral derivative closed-loop feedback and control of rf, rf amplitude, and mass spectrometer sensitivity. Also provided are dc offsets and resonant dipole excitation for mass selective accumulation in applications involving quadrupole ion traps; rf phase locking and phase shifting for external loading of a quadrupole ion trap; and multichannel scaling of acquired mass spectra. The functionality of the MSC is task specific, and is easily modified by simply loading FPGA registers or reprogramming FPGA firmware.

  11. The Direct Digital Modulation of Traveling Wave Tubes

    NASA Technical Reports Server (NTRS)

    Radhamohan, Ranjan S.

    2004-01-01

    Traveling wave tube (TWT) technology, first described by Rudolf Kompfner in the early 1940s, has been a key component of space missions from the earliest communication satellites in the 1960s to the Cassini probe today. TWTs are essentially signal amplifiers that have the special capability of operating at microwave frequencies. The microwave frequency range, which spans from approximately 500 MHz to 300 GHz, is shared by many technologies including cellular phones, satellite television, space communication, and radar. TWT devices are superior in reliability, weight, and efficiency to solid-state amplifiers at the high power and frequency levels required for most space missions. TWTs have three main components -an electron gun, slow wave structure, and collector. The electron gun generates an electron beam that moves along the length of the tube axis, inside of the slow wave circuit. At the same time, the inputted signal is slowed by its travel through the coils of the helical slow wave circuit. The interaction of the electron beam and this slowed signal produces a transfer of kinetic energy to the signal, and in turn, amplification. At the end of its travel, the spent electron beam moves into the collector where its remaining energy is dissipated as heat or harnessed for reuse. TWTs can easily produce gains in the tens of decibels, numbers that are suitable for space missions. To date, however, TWTs have typically operated at fixed levels of gain. This gain is determined by various, unchanging, physical factors of the tube. Traditionally, to achieve varying gain, an input signal s amplitude has had to first be modulated by a separate device before being fed into the TWT. This is not always desirable, as significant distortion can occur in certain situations. My mentor, Mr. Dale Force, has proposed an innovative solution to this problem called direct digital modulation . The testing and implementation of this solution is the focus of my summer internship. The

  12. The Direct Digital Modulation of Traveling Wave Tubes

    NASA Technical Reports Server (NTRS)

    Radhamohan, Ranjan S.

    2004-01-01

    Traveling wave tube (TWT) technology, first described by Rudolf Kompfner in the early 1940s, has been a key component of space missions from the earliest communication satellites in the 1960s to the Cassini probe today. TWTs are essentially signal amplifiers that have the special capability of operating at microwave frequencies. The microwave frequency range, which spans from approximately 500 MHz to 300 GHz, is shared by many technologies including cellular phones, satellite television, space communication, and radar. TWT devices are superior in reliability, weight, and efficiency to solid-state amplifiers at the high power and frequency levels required for most space missions. TWTs have three main components -an electron gun, slow wave structure, and collector. The electron gun generates an electron beam that moves along the length of the tube axis, inside of the slow wave circuit. At the same time, the inputted signal is slowed by its travel through the coils of the helical slow wave circuit. The interaction of the electron beam and this slowed signal produces a transfer of kinetic energy to the signal, and in turn, amplification. At the end of its travel, the spent electron beam moves into the collector where its remaining energy is dissipated as heat or harnessed for reuse. TWTs can easily produce gains in the tens of decibels, numbers that are suitable for space missions. To date, however, TWTs have typically operated at fixed levels of gain. This gain is determined by various, unchanging, physical factors of the tube. Traditionally, to achieve varying gain, an input signal s amplitude has had to first be modulated by a separate device before being fed into the TWT. This is not always desirable, as significant distortion can occur in certain situations. My mentor, Mr. Dale Force, has proposed an innovative solution to this problem called direct digital modulation . The testing and implementation of this solution is the focus of my summer internship. The

  13. Porous graphitic carbon nitride synthesized via direct polymerization of urea for efficient sunlight-driven photocatalytic hydrogen production

    NASA Astrophysics Data System (ADS)

    Zhang, Yuewei; Liu, Jinghai; Wu, Guan; Chen, Wei

    2012-08-01

    Energy captured directly from sunlight provides an attractive approach towards fulfilling the need for green energy resources on the terawatt scale with minimal environmental impact. Collecting and storing solar energy into fuel through photocatalyzed water splitting to generate hydrogen in a cost-effective way is desirable. To achieve this goal, low cost and environmentally benign urea was used to synthesize the metal-free photocatalyst graphitic carbon nitride (g-C3N4). A porous structure is achieved via one-step polymerization of the single precursor. The porous structure with increased BET surface area and pore volume shows a much higher hydrogen production rate under simulated sunlight irradiation than thiourea-derived and dicyanamide-derived g-C3N4. The presence of an oxygen atom is presumed to play a key role in adjusting the textural properties. Further improvement of the photocatalytic function can be expected with after-treatment due to its rich chemistry in functionalization.Energy captured directly from sunlight provides an attractive approach towards fulfilling the need for green energy resources on the terawatt scale with minimal environmental impact. Collecting and storing solar energy into fuel through photocatalyzed water splitting to generate hydrogen in a cost-effective way is desirable. To achieve this goal, low cost and environmentally benign urea was used to synthesize the metal-free photocatalyst graphitic carbon nitride (g-C3N4). A porous structure is achieved via one-step polymerization of the single precursor. The porous structure with increased BET surface area and pore volume shows a much higher hydrogen production rate under simulated sunlight irradiation than thiourea-derived and dicyanamide-derived g-C3N4. The presence of an oxygen atom is presumed to play a key role in adjusting the textural properties. Further improvement of the photocatalytic function can be expected with after-treatment due to its rich chemistry in

  14. Ultra-hard polycrystalline diamond synthesized by direct conversion of graphite using multianvil apparatus

    NASA Astrophysics Data System (ADS)

    Irifune, T.; Kurio, A.; Sakamoto, S.; Inoue, T.; Sumiya, H.

    2002-12-01

    Occurrence of sintered polycrystalline diamonds, such as carbonado and ballas, has been reported in some diamond mines, although the production rate has been very limited and their origin has been unsolved. These polycrystalline diamonds are most valuable in industrial applications because they are often harder than single crystal diamonds, whose hardness depends largely upon the crystallographic directions. Synthesis of pure polycrystalline diamond, however, has been unsuccessful, whereas single crystal diamond has been produced using some catalysts or solvents by high-pressure synthesis since its success in 1950's. Here, we report the first synthesis of a pure massive polycrystalline diamond by direct conversion of graphite without any catalysts/solvents under static high pressure and high temperature. Thus synthesized diamond at pressures 12-25 GPa and temperatures 2300-2500°C was optically transparent and colorless, and consisted of minute crystals of typically 1020 nanometers. Moreover, it was found that the Knoop hardness of the present diamonds is 110-140 GPa, which is higher than those of any known materials, including high quality synthetic type IIa diamond

  15. Direct digital control of air washer cooling system

    SciTech Connect

    Elben, T.; Roseblock, R.; Lawler, R.; McCord, J.

    1990-01-01

    The purpose of this project was to make a practical evaluation of using new technology to extend the life of obsolete HVAC mechanical equipment. The specific exercises in this project involved the application of software driven control algorithms to operate and manage open loop air washer cooling systems in the air handling units located in the Municipal Auditorium in Kansas City, Missouri. The specific opportunity evaluated in this project involved eight air handling units at the Municipal Auditorium. The air handling systems utilize outdated air washer cooling systems that provide air conditioning and dehumidification to the areas they serve. We utilized direct digital control to assume total control of the operation of the air handling units. We also found it necessary to upgrade some components of the air handling units in order to allow the new control applications to execute their functions. This report describes the plan used to execute the project and the results. 20 tabs.

  16. Size Dependence of the Bandgap of Plasma Synthesized Silicon Nanoparticles Through Direct Introduction of Sulfur Hexafluoride

    SciTech Connect

    Theingi, S.; Guan, T. Y.; Kendrick, C.; Klafehn, G.; Gorman, B. P.; Taylor, P. C.; Lusk, M. T.; Stradins, Pauls; Collins, R. T.

    2015-10-19

    Developing silicon nanoparticle (SiNP) synthesis techniques that allow for straightforward control of nanoparticle size and associated optical properties is critical to potential applications of these materials. In addition, it is, in general, hard to probe the absorption threshold in these materials due to silicon's low absorption coefficient. In this study, size is controlled through direct introduction of sulfur hexafluoride (SF6) into the dilute silane precursor of plasma synthesized SiNPs. Size reduction by nearly a factor of two with high crystallinity independent of size is demonstrated. Optical absorption spectra of the SiNPs in the vicinity of the bandgap are measured using photothermal deflection spectroscopy. Bandgap as a function of size is extracted taking into account the polydispersity of the samples. A systematic blue shift inabsorption edge due to quantum confinement in the SiNPs is observed with increasing flow of SF6. Photoluminescence (PL) spectra show a similar blue shift with size. However, a ~300 meV difference in energy between emission and absorption for all sizes suggests that PL emission involves a defect related process. While PL may allow size-induced shifts in the bandgap of SiNPs to be monitored, it cannot be relied on to give an accurate value for the bandgap as a function of size.

  17. Size dependence of the bandgap of plasma synthesized silicon nanoparticles through direct introduction of sulfur hexafluoride

    SciTech Connect

    Theingi, S.; Guan, T. Y.; Klafehn, G.; Taylor, P. C.; Lusk, M. T.; Collins, R. T.; Kendrick, C.; Gorman, B. P.; Stradins, P.

    2015-10-19

    Developing silicon nanoparticle (SiNP) synthesis techniques that allow for straightforward control of nanoparticle size and associated optical properties is critical to potential applications of these materials. In addition, it is, in general, hard to probe the absorption threshold in these materials due to silicon's low absorption coefficient. In this study, size is controlled through direct introduction of sulfur hexafluoride (SF{sub 6}) into the dilute silane precursor of plasma synthesized SiNPs. Size reduction by nearly a factor of two with high crystallinity independent of size is demonstrated. The optical absorption spectra of the SiNPs in the vicinity of the bandgap are measured using photothermal deflection spectroscopy. Bandgap as a function of size is extracted taking into account the polydispersity of the samples. A systematic blue shift in absorption edge due to quantum confinement in the SiNPs is observed with increasing flow of SF{sub 6}. Photoluminescence (PL) spectra show a similar blue shift with size. However, a ∼300 meV difference in energy between emission and absorption for all sizes suggests that PL emission involves a defect related process. This shows that, while PL may allow size-induced shifts in the bandgap of SiNPs to be monitored, it cannot be relied on to give an accurate value for the bandgap as a function of size.

  18. Reviews and syntheses: Australian vegetation phenology: new insights from satellite remote sensing and digital repeat photography

    NASA Astrophysics Data System (ADS)

    Moore, Caitlin E.; Brown, Tim; Keenan, Trevor F.; Duursma, Remko A.; van Dijk, Albert I. J. M.; Beringer, Jason; Culvenor, Darius; Evans, Bradley; Huete, Alfredo; Hutley, Lindsay B.; Maier, Stefan; Restrepo-Coupe, Natalia; Sonnentag, Oliver; Specht, Alison; Taylor, Jeffrey R.; van Gorsel, Eva; Liddell, Michael J.

    2016-09-01

    Phenology is the study of periodic biological occurrences and can provide important insights into the influence of climatic variability and change on ecosystems. Understanding Australia's vegetation phenology is a challenge due to its diverse range of ecosystems, from savannas and tropical rainforests to temperate eucalypt woodlands, semi-arid scrublands, and alpine grasslands. These ecosystems exhibit marked differences in seasonal patterns of canopy development and plant life-cycle events, much of which deviates from the predictable seasonal phenological pulse of temperate deciduous and boreal biomes. Many Australian ecosystems are subject to irregular events (i.e. drought, flooding, cyclones, and fire) that can alter ecosystem composition, structure, and functioning just as much as seasonal change. We show how satellite remote sensing and ground-based digital repeat photography (i.e. phenocams) can be used to improve understanding of phenology in Australian ecosystems. First, we examine temporal variation in phenology on the continental scale using the enhanced vegetation index (EVI), calculated from MODerate resolution Imaging Spectroradiometer (MODIS) data. Spatial gradients are revealed, ranging from regions with pronounced seasonality in canopy development (i.e. tropical savannas) to regions where seasonal variation is minimal (i.e. tropical rainforests) or high but irregular (i.e. arid ecosystems). Next, we use time series colour information extracted from phenocam imagery to illustrate a range of phenological signals in four contrasting Australian ecosystems. These include greening and senescing events in tropical savannas and temperate eucalypt understorey, as well as strong seasonal dynamics of individual trees in a seemingly static evergreen rainforest. We also demonstrate how phenology links with ecosystem gross primary productivity (from eddy covariance) and discuss why these processes are linked in some ecosystems but not others. We conclude that

  19. Digital Quantification of miRNA directly in plasma using Integrated Comprehensive Droplet Digital Detection

    PubMed Central

    Zhang, Kaixiang; Kang, Dong-Ku; Ali, M. Monsur; Liu, Linan; Labanieh, Louai; Lu, Mengrou; Riazifar, Hamidreza; Nguyen, Thi N.; Zell, Jason A.; Digman, Michelle A.; Gratton, Enrico

    2015-01-01

    Quantification of miRNAs in blood can be potentially used for early disease detection, surveillance monitoring and drug response evaluation. However, quantitative and robust measurement of miRNAs in blood is still a major challenge in large part due to their low concentration and complicated sample preparation processes typically required in conventional assays. Here, we present the ‘Integrated Comprehensive Droplet Digital Detection’ (IC 3D) system where the plasma sample containing target miRNAs is encapsulated into microdroplets, enzymatically amplified and digitally counted using a novel, high-throughput 3D particle counter. Using Let-7a as a target, we demonstrate that IC 3D can specifically quantify target miRNA directly from blood plasma at extremely low concentrations ranging from 10s to 10,000 copies/mL in ≤ 3 hours without the need for sample processing such as RNA extraction. Using this new tool, we demonstrate that target miRNA content in colon cancer patient blood is significantly higher than that in healthy donor samples. Our IC 3D system has the potential to introduce a new paradigm for rapid, sensitive and specific detection of low-abundance biomarkers in biological samples with minimal sample processing. PMID:26387763

  20. Digital quantification of miRNA directly in plasma using integrated comprehensive droplet digital detection.

    PubMed

    Zhang, Kaixiang; Kang, Dong-Ku; Ali, M Monsur; Liu, Linan; Labanieh, Louai; Lu, Mengrou; Riazifar, Hamidreza; Nguyen, Thi N; Zell, Jason A; Digman, Michelle A; Gratton, Enrico; Li, Jinghong; Zhao, Weian

    2015-11-07

    Quantification of miRNAs in blood can be potentially used for early disease detection, surveillance monitoring and drug response evaluation. However, quantitative and robust measurement of miRNAs in blood is still a major challenge in large part due to their low concentration and complicated sample preparation processes typically required in conventional assays. Here, we present the 'Integrated Comprehensive Droplet Digital Detection' (IC 3D) system where the plasma sample containing target miRNAs is encapsulated into microdroplets, enzymatically amplified and digitally counted using a novel, high-throughput 3D particle counter. Using Let-7a as a target, we demonstrate that IC 3D can specifically quantify target miRNA directly from blood plasma at extremely low concentrations ranging from 10s to 10 000 copies per mL in ≤3 hours without the need for sample processing such as RNA extraction. Using this new tool, we demonstrate that target miRNA content in colon cancer patient blood is significantly higher than that in healthy donor samples. Our IC 3D system has the potential to introduce a new paradigm for rapid, sensitive and specific detection of low-abundance biomarkers in biological samples with minimal sample processing.

  1. Digital Technology Use by the Students and English Teachers and Self-Directed Language Learning

    ERIC Educational Resources Information Center

    Sert, Nehir; Boynuegri, Ebru

    2017-01-01

    The digital era is a new challenge for teachers. While children get acquainted with the digital technology before the age of six, teachers, who have encountered with the digital world at a later time in their lives, struggle with it. Self-directed learning, which is crucial for lifelong learning, can be enhanced by the use technology particularly…

  2. Ultra-selective high-flux membranes from directly synthesized zeolite nanosheets

    DOE PAGES

    Jeon, Mi Young; Kim, Donghun; Kumar, Prashant; ...

    2017-03-15

    A zeolite with structure type MFI is an aluminosilicate or silicate material that has a three-dimensionally connected pore network, which enables molecular recognition in the size range 0.5-0.6 nm. These micropore dimensions are relevant for many valuable chemical intermediates, and therefore MFI-type zeolites are widely used in the chemical industry as selective catalysts or adsorbents. As with all zeolites, strategies to tailor them for specific applications include controlling their crystal size and shape. Nanometre-thick MFI crystals (nanosheets) have been introduced in pillared and self-pillared (intergrown) architectures, offering improved mass-transfer characteristics for certain adsorption and catalysis applications. Moreover, single (non-intergrown andmore » nonlayered) nanosheets have been used to prepare thin membranes that could be used to improve the energy efficiency of separation processes. However, until now, single MFI nanosheets have been prepared using a multi-step approach based on the exfoliation of layered MFI9,15, followed by centrifugation to remove non-exfoliated particles. This top-down method is time-consuming, costly and low-yield and it produces fragmented nanosheets with submicrometre lateral dimensions. Alternatively, direct (bottom-up) synthesis could produce high-aspect-ratio zeolite nanosheets, with improved yield and at lower cost. Here we use a nanocrystal-seeded growth method triggered by a single rotational intergrowth to synthesize high-aspect-ratio MFI nanosheets with a thickness of 5 nanometres (2.5 unit cells). These high-aspect-ratio nanosheets allow the fabrication of thin and defect-free coatings that effectively cover porous substrates. Finally, these coatings can be intergrown to produce high-flux and ultra-selective MFI membranes that compare favourably with other MFI membranes prepared from existing MFI materials (such as exfoliated nanosheets or nanocrystals).« less

  3. Ultra-selective high-flux membranes from directly synthesized zeolite nanosheets

    NASA Astrophysics Data System (ADS)

    Jeon, Mi Young; Kim, Donghun; Kumar, Prashant; Lee, Pyung Soo; Rangnekar, Neel; Bai, Peng; Shete, Meera; Elyassi, Bahman; Lee, Han Seung; Narasimharao, Katabathini; Basahel, Sulaiman Nasir; Al-Thabaiti, Shaeel; Xu, Wenqian; Cho, Hong Je; Fetisov, Evgenii O.; Thyagarajan, Raghuram; Dejaco, Robert F.; Fan, Wei; Mkhoyan, K. Andre; Siepmann, J. Ilja; Tsapatsis, Michael

    2017-03-01

    A zeolite with structure type MFI is an aluminosilicate or silicate material that has a three-dimensionally connected pore network, which enables molecular recognition in the size range 0.5-0.6 nm. These micropore dimensions are relevant for many valuable chemical intermediates, and therefore MFI-type zeolites are widely used in the chemical industry as selective catalysts or adsorbents. As with all zeolites, strategies to tailor them for specific applications include controlling their crystal size and shape. Nanometre-thick MFI crystals (nanosheets) have been introduced in pillared and self-pillared (intergrown) architectures, offering improved mass-transfer characteristics for certain adsorption and catalysis applications. Moreover, single (non-intergrown and non-layered) nanosheets have been used to prepare thin membranes that could be used to improve the energy efficiency of separation processes. However, until now, single MFI nanosheets have been prepared using a multi-step approach based on the exfoliation of layered MFI, followed by centrifugation to remove non-exfoliated particles. This top-down method is time-consuming, costly and low-yield and it produces fragmented nanosheets with submicrometre lateral dimensions. Alternatively, direct (bottom-up) synthesis could produce high-aspect-ratio zeolite nanosheets, with improved yield and at lower cost. Here we use a nanocrystal-seeded growth method triggered by a single rotational intergrowth to synthesize high-aspect-ratio MFI nanosheets with a thickness of 5 nanometres (2.5 unit cells). These high-aspect-ratio nanosheets allow the fabrication of thin and defect-free coatings that effectively cover porous substrates. These coatings can be intergrown to produce high-flux and ultra-selective MFI membranes that compare favourably with other MFI membranes prepared from existing MFI materials (such as exfoliated nanosheets or nanocrystals).

  4. A Study of Direct Digital Manufactured RF/Microwave Packaging

    NASA Astrophysics Data System (ADS)

    Stratton, John W. I.

    Various facets of direct digital manufactured (DDM) microwave packages are studied. The rippled surface inherent in fused deposition modeling (FDM) fabricated geometries is modeled in Ansoft HFSS, and its effect on the performance of microstrip transmission lines is assessed via simulation and measurement. The thermal response of DDM microstrip transmission lines is analyzed over a range of RF input powers, and linearity is confirmed over that range. Two IC packages are embedded into DDM printed circuit boards, and their performance is analyzed. The first is a low power RF switch, and the second is an RF front end device that includes a low noise amplifier (LNA) and a power amplifier (PA). The RF switch is shown to perform well, as compared to a layout designed for a Rogers 4003C microwave laminate substrate. The LNA performs within datasheet specifications. The power amplifier generates substantial heat, so a thermal management attempt is described. Finally, a capacitively loaded 6dB Wilkinson power divider is designed and fabricated using DDM techniques and materials. Its performance is analyzed and compared to simulation. The device is shown to compare favorably to a similar device fabricated on a Rogers 4003C microwave laminate using traditional printed circuit board techniques.

  5. Comparison of two-dimensional synthesized mammograms versus original digital mammograms alone and in combination with tomosynthesis images.

    PubMed

    Zuley, Margarita L; Guo, Ben; Catullo, Victor J; Chough, Denise M; Kelly, Amy E; Lu, Amy H; Rathfon, Grace Y; Lee Spangler, Marion; Sumkin, Jules H; Wallace, Luisa P; Bandos, Andriy I

    2014-06-01

    To assess interpretation performance and radiation dose when two-dimensional synthesized mammography (SM) images versus standard full-field digital mammography (FFDM) images are used alone or in combination with digital breast tomosynthesis images. A fully crossed, mode-balanced multicase (n = 123), multireader (n = 8), retrospective observer performance study was performed by using deidentified images acquired between 2008 and 2011 with institutional review board approved, HIPAA-compliant protocols, during which each patient signed informed consent. The cohort included 36 cases of biopsy-proven cancer, 35 cases of biopsy-proven benign lesions, and 52 normal or benign cases (Breast Imaging Reporting and Data System [BI-RADS] score of 1 or 2) with negative 1-year follow-up results. Accuracy of sequentially reported probability of malignancy ratings and seven-category forced BI-RADS ratings was evaluated by using areas under the receiver operating characteristic curve (AUCs) in the random-reader analysis. Probability of malignancy-based mean AUCs for SM and FFDM images alone was 0.894 and 0.889, respectively (difference, -0.005; 95% confidence interval [CI]: -0.062, 0.054; P = .85). Mean AUC for SM with tomosynthesis and FFDM with tomosynthesis was 0.916 and 0.939, respectively (difference, 0.023; 95% CI: -0.011, 0.057; P = .19). In terms of the reader-specific AUCs, five readers performed better with SM alone versus FFDM alone, and all eight readers performed better with combined FFDM and tomosynthesis (absolute differences from 0.003 to 0.052). Similar results were obtained by using a nonparametric analysis of forced BI-RADS ratings. SM alone or in combination with tomosynthesis is comparable in performance to FFDM alone or in combination with tomosynthesis and may eliminate the need for FFDM as part of a routine clinical study.

  6. Comparison of Two-dimensional Synthesized Mammograms versus Original Digital Mammograms Alone and in Combination with Tomosynthesis Images

    PubMed Central

    Guo, Ben; Catullo, Victor J.; Chough, Denise M.; Kelly, Amy E.; Lu, Amy H.; Rathfon, Grace Y.; Lee Spangler, Marion; Sumkin, Jules H.; Wallace, Luisa P.; Bandos, Andriy I.

    2014-01-01

    Purpose To assess interpretation performance and radiation dose when two-dimensional synthesized mammography (SM) images versus standard full-field digital mammography (FFDM) images are used alone or in combination with digital breast tomosynthesis images. Materials and Methods A fully crossed, mode-balanced multicase (n = 123), multireader (n = 8), retrospective observer performance study was performed by using deidentified images acquired between 2008 and 2011 with institutional review board approved, HIPAA-compliant protocols, during which each patient signed informed consent. The cohort included 36 cases of biopsy-proven cancer, 35 cases of biopsy-proven benign lesions, and 52 normal or benign cases (Breast Imaging Reporting and Data System [BI-RADS] score of 1 or 2) with negative 1-year follow-up results. Accuracy of sequentially reported probability of malignancy ratings and seven-category forced BI-RADS ratings was evaluated by using areas under the receiver operating characteristic curve (AUCs) in the random-reader analysis. Results Probability of malignancy–based mean AUCs for SM and FFDM images alone was 0.894 and 0.889, respectively (difference, −0.005; 95% confidence interval [CI]: −0.062, 0.054; P = .85). Mean AUC for SM with tomosynthesis and FFDM with tomosynthesis was 0.916 and 0.939, respectively (difference, 0.023; 95% CI: −0.011, 0.057; P = .19). In terms of the reader-specific AUCs, five readers performed better with SM alone versus FFDM alone, and all eight readers performed better with combined FFDM and tomosynthesis (absolute differences from 0.003 to 0.052). Similar results were obtained by using a nonparametric analysis of forced BI-RADS ratings. Conclusion SM alone or in combination with tomosynthesis is comparable in performance to FFDM alone or in combination with tomosynthesis and may eliminate the need for FFDM as part of a routine clinical study. © RSNA, 2014 PMID:24475859

  7. How Digital Scaffolds in Games Direct Problem-Solving Behaviors

    ERIC Educational Resources Information Center

    Sun, Chuen-Tsai; Wang, Dai-Yi; Chan, Hui-Ling

    2011-01-01

    Digital systems offer computational power and instant feedback. Game designers are using these features to create scaffolding tools to reduce player frustration. However, researchers are finding some unexpected effects of scaffolding on strategy development and problem-solving behaviors. We used a digital Sudoku game named "Professor Sudoku" to…

  8. Catalytic wet peroxide oxidation of azo dye (Direct Blue 15) using solvothermally synthesized copper hydroxide nitrate as catalyst.

    PubMed

    Zhan, Yuzhong; Zhou, Xiang; Fu, Bei; Chen, Yiliang

    2011-03-15

    Copper hydroxide nitrate (Cu(2)(OH)(3)NO(3)) was synthesized solvothermally in anhydrous ethanol and characterized by XRD, FTIR, TG-DTA and SEM. The peroxide degradation of an azo dye (Direct Blue 15) on this material was evaluated by examining catalyst loading, initial pH, hydrogen peroxide dosage, initial dye concentration and temperature. The leaching of Cu from the copper hydroxide nitrate during the reaction was also measured. The copper hydroxide nitrate synthesized solvothermally, which was of a novel spherical morphology with complex secondary structures and contained high-dispersed Cu(2)O impurity, showed good performance for oxidation degradation of the azo dye, especially high catalytic activity, high utilization of hydrogen peroxide and a wide pH range, whereas the copper hydroxide nitrate synthesized by the direct reaction of copper nitrate and sodium hydroxide showed low catalytic activity.

  9. Direct Observation of Two Proton Radioactivity Using Digital Photography

    SciTech Connect

    Rykaczewski, Krzysztof Piotr; Pfutzner, M.; Dominik, Wojciech; Janas, Z.; Miernik, K.; Bingham, C. R.; Czyrkowski, Henryk; Cwiok, Mikolaj; Darby, Iain; Dabrowski, Ryszard; Ginter, T. N.; Grzywacz, Robert Kazimierz; Karny, M.; Korgul, A.; Kusmierz, Waldemar; Liddick, Sean; Rajabali, Mustafa; Stolz, A.

    2007-01-01

    Recently the observation of a new type of spontaneous radioactive decay has been claimed in which two protons are simultaneously ejected by an atomic nucleus from the ground state1,2,3. Experimental data obtained for the extremely neutron-deficient nuclei 45Fe and 54Zn, were interpreted as the first evidence of such a decay mode which has been sought since 1960.4 However, the technique applied in those studies allowed only measurements of the decay time and the total energy released. Particles emitted in the decay were not identified and the conclusions had to be supported by theoretical arguments. Here we show for the first time, directly and unambiguously, that 45Fe indeed disintegrates by two-proton decay. Furthermore, we demonstrate that the decay branch of this isotope leads to various particle emission channels including two-proton and three-proton emission. To achieve this result we have developed a new type of detector V the Optical Time Projection Chamber (OTPC) in which digital photography is applied to nuclear physics for the first time. The detector records images of tracks from charged particles, allowing for their unambiguous identification and the reconstruction of decay events in three dimensions. This new and simple technique provides a powerful method to identify exotic decay channels involving emission of charged particles. It is expected that further studies with the OTPC device will yield important information on nuclei located at and beyond the proton drip-line, thus providing new material for testing and improving models of very unstable atomic nuclei.

  10. Direct digital manufacturing of autonomous centrifugal microfluidic device

    NASA Astrophysics Data System (ADS)

    Ukita, Yoshiaki; Takamura, Yuzuru; Utsumi, Yuichi

    2016-06-01

    This paper presents strategies that attempt to solve two key problems facing the commercialization of microfluidics: cost reduction in microfluidic chip manufacturing and microfluidic device driver development. To reduce the cost of microfluidic chip manufacturing, we propose to use of three-dimensional (3D) printers for direct digital manufacturing (DDM). An evaluation of 3D micro-scale structure printing using several 3D printers is reported, and some of the technical issues to be addressed in the future are suggested. To evaluate micro-scale printing, three types of 3D printers, with the ability to print structures on the scale of several hundred meters, were selected by first screening six 3D printers. Line and space patterns with line widths of 100-500 µm and an aspect ratio of one were printed and evaluated. The estimated critical dimension was around 200 µm. The manufacturing of a monolithic microfluidic chip with embedded channels was also demonstrated. Monolithic microfluidic chips with embedded microchannels having 500 × 500 and 250 × 250 µm2 cross sections and 2-20 mm lengths were printed, and the fidelity of the channel shape, residual supporting material, and flow of liquid water were evaluated. The liquid flow evaluation showed that liquid water could flow through all of the microchannels with the 500 × 500 µm2 cross section, whereas this was not possible through some of the channels with the 250 × 250 µm2 cross section because of the residual resin or supporting material. To reduce the device-driver cost, we propose to use of the centrifugal microfluidic concept. An autonomous microfluidic device that could implement sequential flow control under a steadily rotating condition was printed. Four-step flow injection under a steadily rotating condition at 1500 rpm was successfully demonstrated without any external triggering such as changing the rotational speed.

  11. Apparatus for direct-to-digital spatially-heterodyned holography

    DOEpatents

    Thomas, Clarence E.; Hanson, Gregory R.

    2006-12-12

    An apparatus operable to record a spatially low-frequency heterodyne hologram including spatially heterodyne fringes for Fourier analysis includes: a laser; a beamsplitter optically coupled to the laser; an object optically coupled to the beamsplitter; a focusing lens optically coupled to both the beamsplitter and the object; a digital recorder optically coupled to the focusing lens; and a computer that performs a Fourier transform, applies a digital filter, and performs an inverse Fourier transform. A reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form a spatially low-frequency heterodyne hologram including spatially heterodyne fringes for Fourier analysis which is recorded by the digital recorder, and the computer transforms the recorded spatially low-frequency heterodyne hologram including spatially heterodyne fringes and shifts axes in Fourier space to sit on top of a heterodyne carrier frequency defined by an angle between the reference beam and the object beam and cuts off signals around an original origin before performing the inverse Fourier transform.

  12. Direct measurement of newly synthesized ATP dissociation kinetics in sarcoplasmic reticulum ATPase

    SciTech Connect

    Teruel-Puche, J.; Kurzmack, M.; Inesi, G.

    1987-05-01

    Incubation of SR vesicles with CaS and (TSP)acetylphosphate, yields steady state levels of (TSP)phosphorylated enzyme (ATPase) intermediate and high concentrations of CaS in the lumen of the vesicles. At this time, addition of ADP (and EGTA to lower the CaS concentration in the medium outside the vesicles) results in single cycle formation of (el-TSP)ATP by transfer of (TSP)phosphate from the enzyme intermediate to ADP. The phosphoenzyme decay and ATP formation exhibit a fast component within the first 20 msec following addition of ADP, and a slower component reaching an asymptote in approximately 100 msec. They have now measured by a rapid filtration method the fraction of newly synthesized ATP which is bound to the enzyme, as opposed to the fraction dissociated into the medium. They find that nearly all the ATP formed during the initial burst is still bound to the enzyme within the initial 20 msec of reaction. Dissociation of newly synthesized ATP occurs then with approximately 13 sec rate constant, permitting reequilibration of the system and further formation of ATP. The rate limiting effect of ATP dissociation and other partial reactions on the slow component of single cycle ATP synthesis is evaluated by appropriate kinetic simulations.

  13. [Image quality and detection performance of a direct digital radiography system].

    PubMed

    Ideguchi, Tadamitsu; Matsuda, Katsuhiko; Himuro, Kazuhiko; Kuwahara, Rie; Miyazaki, Hidetsune; Hazeyama, Hiroyuki; Kumazawa, Seiji; Kawaji, Yasuyuki; Yoshida, Akira; Matsumoto, Masao; Higashida, Yoshiharu

    2006-03-20

    The physical characteristics of a direct amorphous Selenium (a-Se) digital fluoroscopy and radiography system were investigated. Pre-sampled modulation transfer functions (MTF) were measured using a slit method. Noise power spectra were determined for different input exposures by fast Fourier transform of uniformly exposed samples. The MTFs of direct digital radiography systems showed significantly higher values than those of indirect digital radiography and screen-film systems. The direct digital radiography systems showed higher noise levels compared with those of indirect systems under roughly the same exposure conditions. Contrast-detail analysis was performed to compare detection by direct digital radiography systems with that of the screen-film (FUJI HG-M2/UR2) systems. The average contrast-detail curves of digital and film images were obtained from the results of observation. Image quality figures (IQF) were also calculated from the individual observer performance tests. The results indicated that digital contrast-detail curves and IQF are, on average, are equal those of the screen-film system.

  14. Construction and evaluation of an automated light directed protein-detecting microarray synthesizer.

    PubMed

    Marthandan, N; Klyza, S; Li, S; Kwon, Y U; Kodadek, T; Garner, H R

    2008-03-01

    We have designed, constructed, and evaluated an automated instrument that has produced high-density arrays with more than 30 000 peptide features within a 1.5 cm(2) area of a glass slide surface. These arrays can be used for high throughput library screening for protein binding ligands, for potential drug candidate molecules, or for discovering biomarkers. The device consists of a novel fluidics system, a relay control electrical system, an optics system that implements Texas Instruments' digital micromirror device (DMD), and a microwave source for accelerated synthesis of peptide arrays. The instrument implements two novel solid phase chemical synthesis strategies for producing peptide and peptoid arrays. Biotin-streptavidin and DNP anti-DNP (dinitrophenol) models of antibody small molecule interactions were used to demonstrate and evaluate the instrument's capability to produce high-density protein detecting arrays. Several screening assay and detection schemes were explored with various levels of efficiency and assays with sensitivity of 10 nM were also possible.

  15. An investigation on directionally dependent fracture toughness behavior of monolithic nickel gradient material synthesized from electroplating

    NASA Astrophysics Data System (ADS)

    Farooq, Ahmad; El-Aty, Ali Abd; Ahmed, Tauseef; Tai-Chi, Chang

    2017-07-01

    Bulk sized continuous and monolithic pure Nickel gradient material is successfully developed using electroplating method. Great emphasis is given on controlling the direction of the gradient for the samples. The gradient belt for each Nickel gradient material consisted of grain size from maximum 4 µm to minimum 20nm, with the belt transcending from coarse towards ultrafine to finally nano-grain structure. Crack is propagated from Coarse to Nano-grain gradient Nickel and vice versa in order to procure the J-integral (Jic) for each sample according to ASTM standard E-1820 and deduce the fracture properties under each condition. Under such conditions when crack propagated from coarse to nano direction, Jmax is found to be 215kJ/m2 while crack propagating from Nano to Coarse direction, Jmax is found to be 62kJ/m2. Such dual polarized Jic within a single material is unique, especially for nickel whose Jicin literature for coarse grain (95 µm) was around 225kJ/m2 and ultrafine grain (300nm) was 100 kJ/m2, meaning the nickel gradient material consisting the grain gradient belt between 4 µm-20nm exhibits similar fracture toughness as pure coarse grain almost 20 times larger. Such gradient material exhibiting directionally dependent fracture toughness behavior can most certainly be much stronger under tensile conditions while keeping high fracture toughness.

  16. Characterization and anticorrosion properties of carbon nanotubes directly synthesized on Ni foil using ethanol

    NASA Astrophysics Data System (ADS)

    Jeong, Namjo; Jwa, Eunjin; Kim, Chansoo; Hwang, Kyo Sik; Park, Soon-cheol; Jang, Moon Suk

    2016-07-01

    In this work, we describe the direct growth of carbon nanofilaments by the catalytic decomposition of ethanol on untreated polycrystalline Ni foil. Our work focuses on the effects of synthesis conditions on the growth of the carbon nanofilaments and their growth mechanism. Direct growth of carbon nanotubes (CNTs) is more favorable on lower-purity Ni foil. The highest yield was obtained at approximately 750 °C. The average diameter of the CNTs was approximately 20-30 nm. Raman spectra revealed that the increase of H2 concentration in the carrier gas and synthesis temperature induced the growth of better-graphitized CNTs. Additionally, we investigated the anticorrosion properties of as-prepared products under simulated seawater conditions. The corrosion rate of the CNT/Ni foil system was maximally 50-60 times slower than that of the as-received Ni foil, indicating that the CNT coating may be a good candidate for corrosion inhibition.

  17. Direct write of microlens array using digital projection photopolymerization

    SciTech Connect

    Lu Yi; Chen Shaochen

    2008-01-28

    Microlens array is a key element in the field of information processing, optoelectronics, and integrated optics. Many existing fabrication processes remain expensive and complicated even though relatively low-cost replication processes have been developed. Here, we demonstrate the fabrication of microlens arrays through projection photopolymerization using a digital micromirror device (DMD) as a dynamic photomask. The DMD projects grayscale images, which are designed in a computer, onto a photocurable resin. The resin is then solidified with its thickness determined by a grayscale ultraviolet light and exposure time. Therefore, various geometries can be formed in a single-step, massively parallel fashion. We present microlens arrays made of acrylate-based polymer precursor. The physical and optical characteristics of the resulting lenses suggest that this fabrication technique is potentially suitable for applications in integrated optics.

  18. Randomized controlled trial comparing direct intraoral digitization and extraoral digitization after impression taking.

    PubMed

    Quaas, Sebastian; Loos, René; Rudolph, Heike; Luthardt, Ralph G

    2015-01-01

    This study aimed to evaluate the correspondence of intraoral digitization (ID) with extraoral digitization (ED) after impression taking. One-stage putty-and wash impressions and ID were carried out in a randomized order for 10 subjects. The impressions were used to make casts, which were then subjected to ED. ID datasets were aligned to create computer-aided design reference models. Deviations between ID and ED were calculated. The mean positive and negative deviations were 37.7 and -48.4 µm, respectively, for one quadrant. The results showed that the ID system is well suited for the acquisition of single-tooth restorations and is of limited suitability for the acquisition of small multiple unit restorations.

  19. Inorganic chemistry: Direct syntheses from pure liquid SO3 and from trivalent and pentavalent nitrogen derivatives

    NASA Technical Reports Server (NTRS)

    Vandorpe, B.; Heubel, J.

    1977-01-01

    From pure liquid SO3 direct synthesis reactions were carried out with N2O5, NO2Cl, NOCl which yielded N2O54SO3, 3SO3, 2SO3-NO2Cl2SO3-NOCl2SO3 and NOCl2SO3, the latter being obtained for the first time in the pure state. In all cases the crystallized product was obtained by separating the constituents of the mixture and then going through a single viscous liquid phase.

  20. Multifunction audio digitizer. [producing direct delta and pulse code modulation

    NASA Technical Reports Server (NTRS)

    Monford, L. G., Jr. (Inventor)

    1974-01-01

    An illustrative embodiment of the invention includes apparatus which simultaneously produces both direct delta modulation and pulse code modulation. An input signal, after amplification, is supplied to a window comparator which supplies a polarity control signal to gate the output of a clock to the appropriate input of a binary up-down counter. The control signals provide direct delta modulation while the up-down counter output provides pulse code modulation.

  1. Characterization of Nanocrystalline Nickel-Cobalt Alloys Synthesized by Direct and Pulse Electrodeposition

    NASA Astrophysics Data System (ADS)

    Salehi, M.; Saidi, A.; Ahmadian, M.; Raeissi, K.

    2014-01-01

    Nanocrystalline Ni-Co alloys are electrodeposited by direct (DC) and pulse current (PC) in an electrolyte solution which consisted of nickel sulfate, cobalt sulfate and boric acid. Electrodeposition parameters including current density, electrolyte pH and pulse times in a single electrolyte bath were changed. XRD pattern showed that the structure of the alloys depends on Co content and the synthesis parameter and changed from single phase structure (fcc) to dual phase structure (fcc + hcp). The Co content in the deposited alloys declined from 70 at.% to 50 at.% by increasing in direct current from 70 mA/cm2 to 115 mA/cm2 and also decreased from 75 at.% to 33 at.% with decrease in pH values from 4 to 2. By applying PC the Co content changed from 76 at.% to 41 at.%. Magnetic properties measurements showed the saturation magnetization (Ms) increased with increasing the Co content. There was no significant effect on coercivity values (Hc) with change in Co content and about 40 Oe was obtained for all samples. The grain size of deposited alloys obtained between 24-58 nm and 15-21 nm by applying DC and PC, respectively.

  2. Microintaglio Printing of In situ Synthesized Proteins Enables Rapid Printing of High-Density Protein Microarrays Directly from DNA Microarrays

    NASA Astrophysics Data System (ADS)

    Biyani, Manish; Moriyasu, Junpei; Tanaka, Yoko; Sato, Shusuke; Ueno, Shingo; Ichiki, Takanori

    2013-08-01

    A simple and versatile approach to the simultaneous on-chip synthesis and printing of proteins has been studied for high-density protein microarray applications. The method used is based on the principle of intaglio printing using microengraved plates. Unlike conventional approaches that require multistep reactions for synthesizing proteins off the chip followed by printing using a robotic spotter, our approach demonstrates the following: (i) parallel and spotter-free printing of high-density protein microarrays directly from a type of DNA microarray and (ii) microcompartmentalization of cell-free coupled transcription/translation reaction and direct transferring of picoliter protein solution per spot to pattern microarrays of 25-100 µm features.

  3. Encapsulation of metal clusters within MFI via interzeolite transformations and direct hydrothermal syntheses and catalytic consequences of their confinement.

    PubMed

    Goel, Sarika; Zones, Stacey I; Iglesia, Enrique

    2014-10-29

    The encapsulation of metal clusters (Pt, Ru, Rh) within MFI was achieved by exchanging cationic metal precursors into a parent zeolite (BEA, FAU), reducing them with H2 to form metal clusters, and transforming these zeolites into daughter structures of higher framework density (MFI) under hydrothermal conditions. These transformations required MFI seeds or organic templates for FAU parent zeolites, but not for BEA, and occurred with the retention of encapsulated clusters. Clusters uniform in size (1.3-1.7 nm) and exposing clean and accessible surfaces formed in BEA and FAU zeolites; their size remained essentially unchanged upon transformation into MFI. Encapsulation selectivities, determined from the relative hydrogenation rates of small (toluene) and large (alkyl arenes) molecules and defined as the ratio of the surface areas of all the clusters in the sample to that of external clusters, were very high (8.1-40.9) for both parent and daughter zeolites. Encapsulation into MFI via direct hydrothermal syntheses was unsuccessful because metal precursors precipitated prematurely at the pH and temperatures required for MFI synthesis. Delayed introduction of metal precursors and F(-) (instead of OH(-)) as the mineralizing agent in hydrothermal syntheses increased encapsulation selectivities, but they remained lower than those achieved via interzeolite transformations. These interconversions provide a general and robust strategy for encapsulation of metals when precursors can be introduced via exchange into a zeolite that can be transformed into target daughter zeolites with higher framework densities, whether spontaneously or by using seeds or structure-directing agents (SDA).

  4. Cytocompatibility of direct water synthesized cadmium selenide quantum dots in colo-205 cells.

    PubMed

    Rodriguez-Torres, Marcos R; Velez, Christian; Zayas, Beatriz; Rivera, Osvaldo; Arslan, Zikri; Gonzalez-Vega, Maxine N; Diaz-Diestra, Daysi; Beltran-Huarac, Juan; Morell, Gerardo; Primera-Pedrozo, Oliva M

    2015-06-01

    the intracellular uptake of TGA-CdSe QDs reveal that the TGA-CdSe QDs were uniformly distributed within the cytosolic side of cell membranes. Our results also suggest that under controlled conditions, direct water-soluble TGA-CdSe QDs can be potentially employed for bio-imaging colo-205 cancer cells with minimal adverse effects.

  5. Cytocompatibility of direct water synthesized cadmium selenide quantum dots in colo-205 cells

    PubMed Central

    Rodriguez-Torres, Marcos R.; Velez, Christian; Zayas, Beatriz; Rivera, Osvaldo; Arslan, Zikri; Gonzalez-Vega, Maxine N.; Diaz-Diestra, Daysi; Beltran-Huarac, Juan; Morell, Gerardo

    2015-01-01

    intracellular uptake of TGA-CdSe QDs reveal that the TGA-CdSe QDs were uniformly distributed within the cytosolic side of cell membranes. Our results also suggest that under controlled conditions, direct water-soluble TGA-CdSe QDs can be potentially employed for bio-imaging colo-205 cancer cells with minimal adverse effects. PMID:26949369

  6. Cytocompatibility of direct water synthesized cadmium selenide quantum dots in colo-205 cells

    NASA Astrophysics Data System (ADS)

    Rodriguez-Torres, Marcos R.; Velez, Christian; Zayas, Beatriz; Rivera, Osvaldo; Arslan, Zikri; Gonzalez-Vega, Maxine N.; Diaz-Diestra, Daysi; Beltran-Huarac, Juan; Morell, Gerardo; Primera-Pedrozo, Oliva M.

    2015-06-01

    intracellular uptake of TGA-CdSe QDs reveal that the TGA-CdSe QDs were uniformly distributed within the cytosolic side of cell membranes. Our results also suggest that under controlled conditions, direct water-soluble TGA-CdSe QDs can be potentially employed for bio-imaging colo-205 cancer cells with minimal adverse effects.

  7. Understanding Digital-Synthesized Photographs through Theories of Knowledge: A Case Study of Tom Bamberger's "Cultured Landscapes"

    ERIC Educational Resources Information Center

    Huang, Yi-hui

    2011-01-01

    With the rapid advancement of technology in the photographic industry, more photographers than ever (willingly or in response to this shift) are replacing their darkroom-based facilities with digital ones. This technological shift has changed the focus of the artmaking process in that photographers now spend more time editing their photographs…

  8. Understanding Digital-Synthesized Photographs through Theories of Knowledge: A Case Study of Tom Bamberger's "Cultured Landscapes"

    ERIC Educational Resources Information Center

    Huang, Yi-hui

    2011-01-01

    With the rapid advancement of technology in the photographic industry, more photographers than ever (willingly or in response to this shift) are replacing their darkroom-based facilities with digital ones. This technological shift has changed the focus of the artmaking process in that photographers now spend more time editing their photographs…

  9. Porous graphitic carbon nitride synthesized via direct polymerization of urea for efficient sunlight-driven photocatalytic hydrogen production.

    PubMed

    Zhang, Yuewei; Liu, Jinghai; Wu, Guan; Chen, Wei

    2012-09-07

    Energy captured directly from sunlight provides an attractive approach towards fulfilling the need for green energy resources on the terawatt scale with minimal environmental impact. Collecting and storing solar energy into fuel through photocatalyzed water splitting to generate hydrogen in a cost-effective way is desirable. To achieve this goal, low cost and environmentally benign urea was used to synthesize the metal-free photocatalyst graphitic carbon nitride (g-C₃N₄). A porous structure is achieved via one-step polymerization of the single precursor. The porous structure with increased BET surface area and pore volume shows a much higher hydrogen production rate under simulated sunlight irradiation than thiourea-derived and dicyanamide-derived g-C₃N₄. The presence of an oxygen atom is presumed to play a key role in adjusting the textural properties. Further improvement of the photocatalytic function can be expected with after-treatment due to its rich chemistry in functionalization.

  10. Sens-A-Ray. A new system for direct digital intraoral radiography.

    PubMed

    Nelvig, P; Wing, K; Welander, U

    1992-12-01

    A new system for direct digital intraoral radiography, Sens-A-Ray, is presented. This system is based on a detector with a charge-coupled device that was designed especially for direct exposure to x-ray radiation. The system also includes interface electronics and an IBM AT-compatible personal computer with a digital I/O with frame memory, a super VGA graphics board, a high-resolution monitor, and software for the exposure, capture, storage, and enhancement of images. An external optical mass storage device is used for permanent storage of images in digital format. A video printer may be used to create hard copies. The system produces radiographic images at a significantly lower exposure than required for E-speed intraoral film. Applications of the system are exemplified, and its basic properties are discussed.

  11. Direct method for video-based navigation using a digital terrain map.

    PubMed

    Lerner, Ronen; Rivlin, Ehud

    2011-02-01

    A novel vision-based navigation algorithm is proposed. The gray levels of two images, together with a Digital Terrain Map (DTM), are directly utilized to define constraints on the navigation parameters. The feasibility of the algorithm is examined both under a simulated environment and using real flight data.

  12. Fast digital zooming system using directionally adaptive image interpolation and restoration.

    PubMed

    Kang, Wonseok; Jeon, Jaehwan; Yu, Soohwan; Paik, Joonki

    2014-01-01

    This paper presents a fast digital zooming system for mobile consumer cameras using directionally adaptive image interpolation and restoration methods. The proposed interpolation algorithm performs edge refinement along the initially estimated edge orientation using directionally steerable filters. Either the directionally weighted linear or adaptive cubic-spline interpolation filter is then selectively used according to the refined edge orientation for removing jagged artifacts in the slanted edge region. A novel image restoration algorithm is also presented for removing blurring artifacts caused by the linear or cubic-spline interpolation using the directionally adaptive truncated constrained least squares (TCLS) filter. Both proposed steerable filter-based interpolation and the TCLS-based restoration filters have a finite impulse response (FIR) structure for real time processing in an image signal processing (ISP) chain. Experimental results show that the proposed digital zooming system provides high-quality magnified images with FIR filter-based fast computational structure.

  13. Combustion synthesized TiO{sub 2} for enhanced photocatalytic activity under the direct sunlight-optimization of titanylnitrate synthesis

    SciTech Connect

    Daya Mani, A.; Laporte, V.; Ghosal, P.; Subrahmanyam, Ch.

    2012-09-15

    Graphical abstract: Effect of oxidant on the combustion synthesis of TiO{sub 2} has been studied by preparing titanylnitrate in four different ways from Ti(IV) iso-propoxide. It is observed that oxidant preparation method has a significant effect on physico-chemical as well as photocatalytic properties of TiO{sub 2}. All the catalysts showed excellent photocatalytic activity than Degussa P-25 under direct sunlight for the degradation of a textile dye (methylene blue), without the need of external light sources, oxygen supply and reactor systems. Highlights: ► Optimized synthesis of titanylnitrate. ► Influence of titanylnitrate synthesis on the physico-chemical properties of TiO{sub 2} prepared by combustion synthesis. ► Development of highly efficient TiO{sub 2} photocatalysts those are active under the direct sunlight in open atmosphere. ► Degradation of the textile dye (methylene blue) under direct sunlight. -- Abstract: Optimized synthesis of Ti-precursor ‘titanylnitrate’ for one step combustion synthesis of N- and C-doped TiO{sub 2} catalysts were reported and characterized by using powder X-ray diffraction (XRD), transmission electron microscopy (TEM), diffused reflectance UV–vis spectroscopy, N{sub 2} adsorption and X-ray photoelectron spectroscopy (XPS). XRD confirmed the formation of TiO{sub 2} anatase and nano-crystallite size which was further confirmed by TEM. UV-DRS confirmed the decrease in the band gap to less than 3.0 eV, which was assigned due to the presence of C and N in the framework of TiO{sub 2} as confirmed by X-ray photoelectron spectroscopy. Degradation of methylene blue in aqueous solution under the direct sunlight was carried out and typical results indicated the better performance of the synthesized catalysts than Degussa P-25.

  14. Comparison of Two Methods of Obtaining Digital Orthodontic Models: Direct vs. Indirect

    DTIC Science & Technology

    2013-05-17

    either a traditional impression or a digital impression taken directly from the dentition . Various manufacturers developed model scanning devices...main advantage to direct intraoral scanning of the dentition is the obvious elimination of potential error that is inherent in creating an impression...of the maxillary and mandibular dentition and associated bite registration. We attempted to reduce the amount of potential error in several ways

  15. Quantum secure direct communication of digital and analog signals using continuum coherent states

    NASA Astrophysics Data System (ADS)

    Guerra, Antônio Geovan de Araújo Holanda; Rios, Francisco Franklin Sousa; Ramos, Rubens Viana

    2016-11-01

    In this work, we present optical schemes for secure direct quantum communication of digital and analog signals using continuum coherent states and frequency-dependent phase modulation. The main advantages of the proposed schemes are that they do not use entangled states and they can be implemented with today technology. The theory of quantum interference of continuum coherent state is described, and the optical setups for secure direct communication are presented and their securities are discussed.

  16. Effect of image compression of direct digital lateral cephalograms on the identification of cephalometric points

    PubMed Central

    Saghaie, Sima; Ghaffari, Roshanak

    2014-01-01

    Background: With increase of digital imaging, the need for storage space and transmission speed also increases. Compressed images need less storage space and decrease the transmission time. However, compression could compromise image quality. The aim of this study was to evaluate the influence of image compression on the identification of cephalometric points on direct digital lateral cephalogram images, compared with the digital imaging and communications in medicine (DICOM) format. Materials and Methods: In this analytical-descriptive study, 19 direct digital lateral cephalograms saved in DICOM format were used. They were converted to joint photographic experts group (JPEG) 2000 format with quality factors 85, 75, and 60 adding up to 76 images (DICOM, JPEG 85, 75, and 60). The images were randomized and eight cephalometric points were identified on each image by a professional, using the x-y coordinate system. Analysis of variance (ANOVA) was applied to investigate if there was a statistically significant difference in the location of cephalometric points between each group of images. All tests were applied at a significance level of 5%. Results: The results did not demonstrate any statistically significant difference in the identification of the eight cephalometric points between the DICOM images and the JPEG2000 quality factors 85, 75, and 60. Conclusion: JPEG2000 images of lateral cephalograms with quality factors 85, 75, and 60 did not demonstrate any alterations in the identification of cephalometric points compared with the DICOM format. JPEG2000 is a reliable file format for the compression of digital lateral cephalograms. PMID:24688556

  17. Bimetallic Nickel/Ruthenium Catalysts Synthesized by Atomic Layer Deposition for Low-Temperature Direct Methanol Solid Oxide Fuel Cells.

    PubMed

    Jeong, Heonjae; Kim, Jun Woo; Park, Joonsuk; An, Jihwan; Lee, Tonghun; Prinz, Fritz B; Shim, Joon Hyung

    2016-11-09

    Nickel and ruthenium bimetallic catalysts were heterogeneously synthesized via atomic layer deposition (ALD) for use as the anode of direct methanol solid oxide fuel cells (DMSOFCs) operating in a low-temperature range. The presence of highly dispersed ALD Ru islands over a porous Ni mesh was confirmed, and the Ni/ALD Ru anode microstructure was observed. Fuel cell tests were conducted using Ni-only and Ni/ALD Ru anodes with approximately 350 μm thick gadolinium-doped ceria electrolytes and platinum cathodes. The performance of fuel cells was assessed using pure methanol at operating temperatures of 300-400 °C. Micromorphological changes of the anode after cell operation were investigated, and the content of adsorbed carbon on the anode side of the operated samples was measured. The difference in the maximum power density between samples utilizing Ni/ALD Ru and Pt/ALD Ru, the latter being the best catalyst for direct methanol fuel cells, was observed to be less than 7% at 300 °C and 30% at 350 °C. The improved electrochemical activity of the Ni/ALD Ru anode compared to that of the Ni-only anode, along with the reduction of the number of catalytically active sites due to agglomeration of Ni and carbon formation on the Ni surface as compared to Pt, explains this decent performance.

  18. Faster processing of multiple spatially-heterodyned direct to digital holograms

    DOEpatents

    Hanson, Gregory R [Clinton, TN; Bingham, Philip R [Knoxville, TN

    2008-09-09

    Systems and methods are described for faster processing of multiple spatially-heterodyned direct to digital holograms. A method includes of obtaining multiple spatially-heterodyned holograms, includes: digitally recording a first spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; digitally recording a second spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; Fourier analyzing the recorded first spatially-heterodyned hologram by shifting a first original origin of the recorded first spatially-heterodyned hologram including spatial heterodyne fringes in Fourier space to sit on top of a spatial-heterodyne carrier frequency defined as a first angle between a first reference beam and a first object beam; applying a first digital filter to cut off signals around the first original origin and performing an inverse Fourier transform on the result; Fourier analyzing the recorded second spatially-heterodyned hologram by shifting a second original origin of the recorded second spatially-heterodyned hologram including spatial heterodyne fringes in Fourier space to sit on top of a spatial-heterodyne carrier frequency defined as a second angle between a second reference beam and a second object beam; and applying a second digital filter to cut off signals around the second original origin and performing an inverse Fourier transform on the result, wherein digitally recording the first spatially-heterodyned hologram is completed before digitally recording the second spatially-heterodyned hologram and a single digital image includes both the first spatially-heterodyned hologram and the second spatially-heterodyned hologram.

  19. Faster processing of multiple spatially-heterodyned direct to digital holograms

    DOEpatents

    Hanson, Gregory R.; Bingham, Philip R.

    2006-10-03

    Systems and methods are described for faster processing of multiple spatially-heterodyned direct to digital holograms. A method includes of obtaining multiple spatially-heterodyned holograms, includes: digitally recording a first spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; digitally recording a second spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; Fourier analyzing the recorded first spatially-heterodyned hologram by shifting a first original origin of the recorded first spatially-heterodyned hologram including spatial heterodyne fringes in Fourier space to sit on top of a spatial-heterodyne carrier frequency defined as a first angle between a first reference beam and a first, object beam; applying a first digital filter to cut off signals around the first original origin and performing an inverse Fourier transform on the result; Fourier analyzing the recorded second spatially-heterodyned hologram by shifting a second original origin of the recorded second spatially-heterodyned hologram including spatial heterodyne fringes in Fourier space to sit on top of a spatial-heterodyne carrier frequency defined as a second angle between a second reference beam and a second object beam; and applying a second digital filter to cut off signals around the second original origin and performing an inverse Fourier transform on the result, wherein digitally recording the first spatially-heterodyned hologram is completed before digitally recording the second spatially-heterodyned hologram and a single digital image includes both the first spatially-heterodyned hologram and the second spatially-heterodyned hologram.

  20. Multiplexed chirp waveform synthesizer

    DOEpatents

    Dudley, Peter A.; Tise, Bert L.

    2003-09-02

    A synthesizer for generating a desired chirp signal has M parallel channels, where M is an integer greater than 1, each channel including a chirp waveform synthesizer generating at an output a portion of a digital representation of the desired chirp signal; and a multiplexer for multiplexing the M outputs to create a digital representation of the desired chirp signal. Preferably, each channel receives input information that is a function of information representing the desired chirp signal.

  1. Simultaneous dual directional strain measurement using spatial phase-shift digital shearography

    NASA Astrophysics Data System (ADS)

    Wang, Yonghong; Gao, Xinya; Xie, Xin; Wu, Sijing; Liu, Yingxue; Yang, Lianxiang

    2016-12-01

    This paper presents a Dual Directional Sheared Spatial Phase-Shift Digital Shearography (DDS-SPS-DS) system for simultaneous measurement of strains/displacement derivative in two directions. Two Michelson Interferometers are used as the shearing device to create two shearograms, one in the x-shearing direction and one in the y-shearing direction, which are recorded by a single CCD camera. Two lasers with different wavelengths are used for illumination, and corresponding band pass filters are applied in front of each Michelson Interferometer to avoid cross-interference between the two shearing direction channels. Two perpendicular shearing directions in the two measurement channels introduce two different spatial frequency carriers whose spectrums are orientated in different directions after Fourier Transform. Phase maps of the recorded two shearograms can be obtained by applying a windowed inverse Fourier transform, which enables simultaneous measurement of dual directional strains/displacement derivatives. The new system is well suited for nondestructive testing and strain measurement with a continuous or dynamic load. The capability of the dual directional spatial phase-shift digital shearography system is described by theoretical discussions as well as experiments.

  2. Electronic polarization-division demultiplexing based on digital signal processing in intensity-modulation direct-detection optical communication systems.

    PubMed

    Kikuchi, Kazuro

    2014-01-27

    We propose a novel configuration of optical receivers for intensity-modulation direct-detection (IM · DD) systems, which can cope with dual-polarization (DP) optical signals electrically. Using a Stokes analyzer and a newly-developed digital signal-processing (DSP) algorithm, we can achieve polarization tracking and demultiplexing in the digital domain after direct detection. Simulation results show that the power penalty stemming from digital polarization manipulations is negligibly small.

  3. Content-based fused off-axis object illumination direct-to-digital holography

    DOEpatents

    Price, Jeffery R.

    2006-05-02

    Systems and methods are described for content-based fused off-axis illumination direct-to-digital holography. A method includes calculating an illumination angle with respect to an optical axis defined by a focusing lens as a function of data representing a Fourier analyzed spatially heterodyne hologram; reflecting a reference beam from a reference mirror at a non-normal angle; reflecting an object beam from an object the object beam incident upon the object at the illumination angle; focusing the reference beam and the object beam at a focal plane of a digital recorder to from the content-based off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; and digitally recording the content based off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis.

  4. Digital EPR with an arbitrary waveform generator and direct detection at the carrier frequency.

    PubMed

    Tseitlin, Mark; Quine, Richard W; Rinard, George A; Eaton, Sandra S; Eaton, Gareth R

    2011-12-01

    A digital EPR spectrometer was constructed by replacing the traditional bridge with an arbitrary waveform generator (AWG) to produce excitation patterns and a high-speed digitizer for direct detection of the spin system response at the carrier frequency. Digital down-conversion produced baseband signals in quadrature with very precise orthogonality. Real-time resonator tuning was performed by monitoring the Fourier transforms of signals reflected from the resonator during frequency sweeps generated by the AWG. The capabilities of the system were demonstrated by rapid magnetic field scans at 256 MHz carrier frequency, and FID and spin echo experiments at 1 and 10 GHz carrier frequencies. For the rapid scan experiments the leakage through a cross-loop resonator was compensated by adjusting the amplitude and phase of a sinusoid at the carrier frequency that was generated with another AWG channel.

  5. Trending now: future directions in digital media for the public health sector.

    PubMed

    Burke-Garcia, Amelia; Scally, Gabriel

    2014-12-01

    Digital media usage is expanding enormously and is starting to be used as a public health intervention and communication tool. It has an ability to increase the reach of public health research and communication, as well as drive measurable behaviour change. But there is an absence of both deep and wide understanding of the opportunities within digital media, i.e. most people think only of Facebook and Twitter when they think of social media; smart, strategic planning for its widespread use is not common practice and rigorous evaluative studies of its effectiveness are few and far between. This paper analyses the published literature on this topic and identifies the top 10 directions that use of digital media is likely to take in the medium term. The analysis strongly supports the position that digital media needs to be taken seriously as a vehicle for public health activity in its own right and not merely as an adjunct to other campaigns. Digital media will continue to develop and move from being an add-on to existing activity to being the major vehicle for significant elements of research, data collection and advocacy. It is important that public health leaders fully understand and engage in its development and use. © The Author 2014. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. for permissions, please e-mail: journals.permissions@oup.com.

  6. Electrospinning directly synthesized metal nanoparticles decorated on both sidewalls of TiO2 nanotubes and their applications.

    PubMed

    Zhang, Guanhua; Duan, Huigao; Lu, Bingan; Xu, Zhi

    2013-07-07

    The hybrid structure of nanoparticle-decorated nanotubes has the advantage of both large specific surface areas of nanoparticles and anisotropic properties of nanotubes, which is desirable for many applications. In this study, Ag nanoparticles on highly porous TiO2 nanotubes (NTs) on both internal and external sidewalls (Ag@TiO2@Ag NTs) are directly synthesized by emulsion electrospinning and thermal evaporation for the first time. The Ag@TiO2@Ag NT heterostructures, which have large surface-to-volume ratios, improved electrical conductivity, and an excellent material synergetic effect, demonstrate excellent electrochemical properties and superior photocatalytic performance. The new method for the synthesis of Ag@TiO2@Ag NT heterostructures can be applied to fabricate various types of other novel metal nanoparticles (for example Au and Pt) on highly porous nanotubes on both internal and external sidewalls. The possible growth mechanism and reasons for excellent electrochemical properties and superior photocatalytic performance were discussed in detail.

  7. Recognition of one-, two-, and three-pair dichotic digits under free and directed recall.

    PubMed

    Strouse, A; Wilson, R H

    1999-01-01

    A one-, two-, and three-pair dichotic digit test was administered to 180 subjects (20-79 years) with varying degrees of hearing sensitivity. The test was carried out under free- and directed-recall response conditions. The results indicated that recognition performance decreased as a function of increasing age. Statistical analysis using analysis of covariance indicated that differences in performance between age groups were not owing to differences in hearing sensitivity. Thus, with the effects of hearing sensitivity removed, age alone accounted for a significant portion of the variability in the data among age groups. Normative data for the free-recall condition are reported for the two lists of randomly interleaved one-, two-, and three-pair digits included on the Tonal and Speech Materials for Auditory Perceptual Assessment, Disc 2.0 (1998) compact disc. A comparison of performance in free- and directed-recall conditions indicated three patterns of results. First, 58 percent of the subjects had normal recognition performance for one-, two-, and three-pair digits under both recall conditions. Second, 39 percent of the subjects had a deficit in the free-recall condition, with normal performance in the directed-recall condition, which was interpreted as representing primarily a cognitive problem. Third, the remaining 3 percent of the subjects showed a deficit in both free- and directed-recall conditions, which was attributed primarily to an auditory problem.

  8. Radiographic determination of canal length direct digital radiography versus conventional radiography.

    PubMed

    Hedrick, R T; Dove, S B; Peters, D D; McDavid, W D

    1994-07-01

    This research compared the length determination images produced by Trophy and Regam direct digital radiographic systems with conventional E-speed radiographs. Size #15 K files were placed in the canals of 19 teeth of cadaver specimens and radiographed in a geometrically standardized bench device. Three evaluators estimated the length adjustment necessary to position the file at the apex. The mean estimated adjustment lengths were compared with the true, anatomically determined adjustment lengths. Statistical analysis with analysis of variance and the Student-Newman-Keuls test indicated no significant difference between direct digital thermal print images and conventional radiographs (p > 0.10). Length adjustment estimates with conventional radiographs were significantly more accurate than Regam high-resolution computer monitor images (p < 0.01). Additionally, it was determined that length adjustment estimates were significantly more accurate when the file was placed short of the apex (p < 0.001). The clinical relevance of these differences is discussed.

  9. The average direct current offset values for small digital audio recorders in an acoustically consistent environment.

    PubMed

    Koenig, Bruce E; Lacey, Douglas S

    2014-07-01

    In this research project, nine small digital audio recorders were tested using five sets of 30-min recordings at all available recording modes, with consistent audio material, identical source and microphone locations, and identical acoustic environments. The averaged direct current (DC) offset values and standard deviations were measured for 30-sec and 1-, 2-, 3-, 6-, 10-, 15-, and 30-min segments. The research found an inverse association between segment lengths and the standard deviation values and that lengths beyond 30 min may not meaningfully reduce the standard deviation values. This research supports previous studies indicating that measured averaged DC offsets should only be used for exclusionary purposes in authenticity analyses and exhibit consistent values when the general acoustic environment and microphone/recorder configurations were held constant. Measured average DC offset values from exemplar recorders may not be directly comparable to those of submitted digital audio recordings without exactly duplicating the acoustic environment and microphone/recorder configurations.

  10. A digital receiver module with direct data acquisition for magnetic resonance imaging systems.

    PubMed

    Tang, Weinan; Sun, Hongyu; Wang, Weimin

    2012-10-01

    A digital receiver module for magnetic resonance imaging (MRI) with detailed hardware implementations is presented. The module is based on a direct sampling scheme using the latest mixed-signal circuit design techniques. A single field-programmable gate array chip is employed to perform software-based digital down conversion for radio frequency signals. The modular architecture of the receiver allows multiple acquisition channels to be implemented on a highly integrated printed circuit board. To maintain the phase coherence of the receiver and the exciter in the context of direct sampling, an effective phase synchronization method was proposed to achieve a phase deviation as small as 0.09°. The performance of the described receiver module was verified in the experiments for both low- and high-field (0.5 T and 1.5 T) MRI scanners and was compared to a modern commercial MRI receiver system.

  11. A digital computer simulation and study of a direct-energy-transfer power-conditioning system

    NASA Technical Reports Server (NTRS)

    Burns, W. W., III; Owen, H. A., Jr.; Wilson, T. G.; Rodriguez, G. E.; Paulkovich, J.

    1974-01-01

    A digital computer simulation technique, which can be used to study such composite power-conditioning systems, was applied to a spacecraft direct-energy-transfer power-processing system. The results obtained duplicate actual system performance with considerable accuracy. The validity of the approach and its usefulness in studying various aspects of system performance such as steady-state characteristics and transient responses to severely varying operating conditions are demonstrated experimentally.

  12. Innovation & evaluation of tangible direct manipulation digital drawing pens for children.

    PubMed

    Lee, Tai-Hua; Wu, Fong-Gong; Chen, Huei-Tsz

    2017-04-01

    Focusing on the theme of direct manipulation, in this study, we proposed a new and innovative tangible user interface (TUI) design concept for a manipulative digital drawing pen. Based on interviews with focus groups brainstorming and experts and the results of a field survey, we selected the most suitable tangible user interface for children between 4 and 7 years of age. Using the new tangible user interface, children could choose between the brush tools after touching and feeling the various patterns. The thickness of the brush could be adjusted by changing the tilt angle. In a subsequent experimental process we compared the differences in performance and subjective user satisfaction. A total of sixteen children, aged 4-7 years participated in the experiment. Two operating system experiments (the new designed tangible digital drawing pen and traditional visual interface-icon-clicking digital drawing pens) were performed at random and in turns. We assessed their manipulation performance, accuracy, brush stroke richness and subjective evaluations. During the experimental process we found that operating functions using the direct manipulation method, and adding shapes and semantic models to explain the purpose of each function, enabled the children to perform stroke switches relatively smoothly. By using direct manipulation digital pens, the children could improve their stroke-switching performance for digital drawing. Additionally, by using various patterns to represent different brushes or tools, the children were able to make selections using their sense of touch, thereby reducing the time required to move along the drawing pens and select icons (The significant differences (p = 0.000, p < 0.01) existed in the manipulation times for drawing thick lines using the crayon function of the two (new and old) drawing pens (new 5.8750 < old 10.7500)). The addition of direct manipulation movements to drawing operations enhanced the drawing results, thereby

  13. Utilization of a digital method to determine the rotation direction in incremental photoelectric encoder

    NASA Astrophysics Data System (ADS)

    Li, Yousheng

    2010-10-01

    The principles of incremental photoelectric encoders are: When a encoder disk rotates, (1)it will produce the pulse signal proportional to the angle; (2) it will also produce the sensing signal of identifying the rotation direction. The way that the existing incremental photoelectric encoders determine the rotation direction is: one encoder disk has 3 code channels: 'A', 'B' and 'Z'. On both 'A' and 'B' code channels, there are a number of evenly distributed grid holes, and they have the same cycle, but with one quarter cycle difference in phase between channel 'A' and 'B'. When disk rotates clockwise, signal phase from 'A' channel is a quarter cycle ahead of that from 'B'; Similarly, when disk rotates counterclockwise, 'B' signal phase will be a quarter cycle ahead of 'A'. Based on the above phenomena, a circuit can identify the rotation direction, which is known as 'Kam-Phase Method'. The mechanism of the new direction recognition method is: When the encoder disk rotates , it continuously generates three kinds of state binary information sequentially. These three states are defined as state 1, state 2, state 3. While rotating clockwise, the state changes in the order of state 1, state 2, state 3, state 1.....; While rotating counterclockwise, the state changes in the sequence of state 1, state 3, state 2, state 1..... The new theory differentiate the digitized state changing sequence between the clockwise and counter clockwise to determine the rotation direction.This method is called as 'Digital Method'. The advantages of applying the digital method for the rotation direction determination in incremental photoelectric encoder are: the code channel structure is simpler and there is no accumulative errors and so on.

  14. Improving the digital workflow: direct transfer from patient to virtual articulator.

    PubMed

    Solaberrieta, Eneko; Minguez, Rikardo; Etxaniz, Olatz; Barrenetxea, Lander

    2013-01-01

    When designing a custom-made dental restoration, using a digital workflow represents an important advance over mechanical tools such as facebows or mechanical articulators. When using virtual scanning procedures, there is a direct transfer from the patient to the articulator. This paper presents a novel methodology to design custom-made restorations. This new approach permits the transfer of all data directly from the patient to the virtual articulator, always taking into account the kinematics of the mandible. Rapid further developments can be expected in the near future.

  15. Event-Triggered Distributed Average Consensus Over Directed Digital Networks With Limited Communication Bandwidth.

    PubMed

    Li, Huaqing; Chen, Guo; Huang, Tingwen; Dong, Zhaoyang; Zhu, Wei; Gao, Lan

    2016-12-01

    In this paper, we consider the event-triggered distributed average-consensus of discrete-time first-order multiagent systems with limited communication data rate and general directed network topology. In the framework of digital communication network, each agent has a real-valued state but can only exchange finite-bit binary symbolic data sequence with its neighborhood agents at each time step due to the digital communication channels with energy constraints. Novel event-triggered dynamic encoder and decoder for each agent are designed, based on which a distributed control algorithm is proposed. A scheme that selects the number of channel quantization level (number of bits) at each time step is developed, under which all the quantizers in the network are never saturated. The convergence rate of consensus is explicitly characterized, which is related to the scale of network, the maximum degree of nodes, the network structure, the scaling function, the quantization interval, the initial states of agents, the control gain and the event gain. It is also found that under the designed event-triggered protocol, by selecting suitable parameters, for any directed digital network containing a spanning tree, the distributed average consensus can be always achieved with an exponential convergence rate based on merely one bit information exchange between each pair of adjacent agents at each time step. Two simulation examples are provided to illustrate the feasibility of presented protocol and the correctness of the theoretical results.

  16. Worldwide survey of direct-to-listener digital audio delivery systems development since WARC-1992

    NASA Technical Reports Server (NTRS)

    Messer, Dion D.

    1993-01-01

    Each country was allocated frequency band(s) for direct-to-listener digital audio broadcasting at WARC-92. These allocations were near 1500, 2300, and 2600 MHz. In addition, some countries are encouraging the development of digital audio broadcasting services for terrestrial delivery only in the VHF bands (at frequencies from roughly 50 to 300 MHz) and in the medium-wave broadcasting band (AM band) (from roughly 0.5 to 1.7 MHz). The development activity increase was explosive. Current development, as of February 1993, as it is known to the author is summarized. The information given includes the following characteristics, as appropriate, for each planned system: coverage areas, audio quality, number of audio channels, delivery via satellite/terrestrial or both, carrier frequency bands, modulation methods, source coding, and channel coding. Most proponents claim that they will be operational in 3 or 4 years.

  17. Airborne Digital Sensor System and GPS-aided inertial technology for direct geopositioning in rough terrain

    USGS Publications Warehouse

    Sanchez, Richard D.

    2004-01-01

    High-resolution airborne digital cameras with onboard data collection based on the Global Positioning System (GPS) and inertial navigation systems (INS) technology may offer a real-time means to gather accurate topographic map information by reducing ground control and eliminating aerial triangulation. Past evaluations of this integrated system over relatively flat terrain have proven successful. The author uses Emerge Digital Sensor System (DSS) combined with Applanix Corporation?s Position and Orientation Solutions for Direct Georeferencing to examine the positional mapping accuracy in rough terrain. The positional accuracy documented in this study did not meet large-scale mapping requirements owing to an apparent system mechanical failure. Nonetheless, the findings yield important information on a new approach for mapping in Antarctica and other remote or inaccessible areas of the world.

  18. Grid artifact reduction for direct digital radiography detectors based on rotated stationary grids with homomorphic filtering

    SciTech Connect

    Kim, Dong Sik; Lee, Sanggyun

    2013-06-15

    Purpose: Grid artifacts are caused when using the antiscatter grid in obtaining digital x-ray images. In this paper, research on grid artifact reduction techniques is conducted especially for the direct detectors, which are based on amorphous selenium. Methods: In order to analyze and reduce the grid artifacts, the authors consider a multiplicative grid image model and propose a homomorphic filtering technique. For minimal damage due to filters, which are used to suppress the grid artifacts, rotated grids with respect to the sampling direction are employed, and min-max optimization problems for searching optimal grid frequencies and angles for given sampling frequencies are established. The authors then propose algorithms for the grid artifact reduction based on the band-stop filters as well as low-pass filters. Results: The proposed algorithms are experimentally tested for digital x-ray images, which are obtained from direct detectors with the rotated grids, and are compared with other algorithms. It is shown that the proposed algorithms can successfully reduce the grid artifacts for direct detectors. Conclusions: By employing the homomorphic filtering technique, the authors can considerably suppress the strong grid artifacts with relatively narrow-bandwidth filters compared to the normal filtering case. Using rotated grids also significantly reduces the ringing artifact. Furthermore, for specific grid frequencies and angles, the authors can use simple homomorphic low-pass filters in the spatial domain, and thus alleviate the grid artifacts with very low implementation complexity.

  19. The Demographics of Exoplanetary Companions to M Dwarfs: Synthesizing Results from Microlensing, Radial Velocity, and Direct Imaging Surveys

    NASA Astrophysics Data System (ADS)

    Clanton, Christian Dwain

    Over the past 20 years, we have learned that exoplanets are ubiquitous throughout our Galaxy and show a diverse set of demographics, yet there is much work to be done to understand this diversity. Determining the distributions of the fundamental properties of exoplanets will provide vital clues regarding their formation and evolution. This is a difficult task, as exoplanet surveys are not uniformly sensitive to the full range of planet parameter space. Various observational biases and selection effects intrinsic to each of the different discovery techniques constrain the types of planets to which they are sensitive. Herein, I record a collection of the first studies to develop and apply the methodology of synthesizing results from multiple detection techniques to construct a statistically-complete census of planetary companions to M dwarfs that samples a wide region of their parameter space. I present a robust comparison of exoplanet discoveries from microlensing and radial velocity (RV) surveys of M dwarfs which infer giant planet frequencies that differ by more than an order of magnitude and are, prima facie, in direct conflict. I demonstrate that current, state-of-the-art RV surveys are capable of detecting only the high-mass tail of the population of planets beyond the ice line inferred by microlensing studies, engendering a large, apparent difference in giant planet frequency. This comparison further establishes that results from these types of surveys are, in fact, consistent over the region of parameter space wherein their sensitivities overlap. A synthesis of results from microlensing and RV surveys yields planet occurrence rates for M dwarfs that span several orders of magnitude in mass and orbital period. On average, each M dwarf hosts about two planets, and while Jupiter and super-Jupiter companions are relatively rare ( 3%), gas giants, in general, are quite common ( 15%). These occurrence rates are significantly lower than those inferred around FGK

  20. A novel approach for using polyphase filter bank in directly digital RF conversion from RF to baseband

    NASA Astrophysics Data System (ADS)

    Zhang, Deying; Jiang, Qin; Ahmed, Mohiuddin

    2012-05-01

    Software defined radio (SDR) hardware platform is in high demand for ultra-wideband digital EW receiver to carry out different mission requirements. Due to the limitations of current Analog-to-Digital conversion (ADC) techniques, the ideal receiver structure of SDR, with digital RF frequency conversion, cannot be achieved. In this article, a new channelization technique called ADC polyphase fast Fourier transformation (ADC PFFT) filter bank channelization is demonstrated. The key concept is to separate the speed at which the two functional units of an ADC - the sample and hold and the quantizer - operate. The sample and hold unit operates at the sampling frequency fs and the quantizer (the speed limiting factor in ADCs) can operate at a much slower rate, fs/M, where M is the decimation factor for digital filter bank. By integrated this ADC PFFT technique in ultra-wideband digital channelized EW receivers, directly digital RF down conversion can be achieved. With the ADC PFFT channelization for RF down conversion and polyphase FFT channelization for IF down conversion, 2-18 GHz frequency coverage can be accomplished in such ultra-wideband digital channelized EW receivers without the requirement of EW receivers being time-shared among outputs from many subbands due to bandwidth limitation in digital IF channelized EW receivers. Because the frequency down conversion from RF to BB are all processed digitally, issues such as image rejection and I/Q imbalance due to analog mixing will be eliminated in the ultrawideband digital channelized EW receivers.

  1. Evaluation of a digital dispenser for direct curve dilutions in a vaccine potency assay.

    PubMed

    Roselle, Christopher; Whitehouse, Dana; Follmer, Thy; Ansbro, Fran; Bouaraphan, Silikhone; Guan, Liming; Wang, Sha-Ke; Shank-Retzlaff, Mary; Verch, Thorsten

    2017-03-01

    Dilutions are a common source of analytical error, both in terms of accuracy and precision, and a common source of analyst mistakes. When serial dilutions are used, errors compound, even when employing laboratory automation. Direct point dilutions instead of serial dilutions can reduce error but is often impractical as they require either large diluent volumes or very small sample volumes when performed with traditional liquid handling equipment. We evaluated preparation of dilution curves using a picoliter digital dispenser, the HP, Inc. / TECAN D300 which is capable of accurately delivering picoliter volumes directly into sample wells filled with assay diluent. Dilution linearity and variability of the direct dilutions were similar to or less than those generated with a traditional liquid handler as measured using a fluorophore assay and an ELISA used to measure vaccine potency. Minimum concentrations for detergent in the dispensed sample were identified but no correlation with detergent characteristics was observed. The tolerance to protein in the sample was evaluated as well with up to 5% BSA having no impact on dispense linearity and precision. We found the digital dispenser to reduce automation complexity while maintaining or improving assay performance in addition to facilitating complex plate lay-outs.

  2. Composite Digital Terrain Models: Synthesizing Aerial and Terrestrial LiDAR with Conventional Survey Data to Monitor Sediment Transport Through the Sunol Dam Removal Site

    NASA Astrophysics Data System (ADS)

    Storesund, R.; Minear, T.; Saleh, R.

    2007-12-01

    In 2006, the San Francisco Public Utilities Commission removed Sunol dam, located on Alameda Creek, near San Francisco California. The primary goals of the project were to improve fish passage, restore a self- sustaining population of steelhead to the watershed, and eliminate an existing public safety hazard. Approximately 28,300 cubic meters of sand and gravel-sized sediment had accumulated upstream of the dam and was left in place to move downstream naturally over a period of several decades. To create a baseline for future monitoring of sediment transport through the dam area, a combination of Aerial LiDAR, Terrestrial LiDAR, and conventional survey data was compiled and synthesized to generate a three dimensional digital model of the study area both upstream and downstream of the damsite. The primary survey method for characterization of above ground topography was Terrestrial LiDAR, with an approximate point spacing of centimeters. In submerged areas conventional survey techniques were used to augment the Aerial and Terrestrial LiDAR data sets. We found this approach to be effective in developing a high accuracy-high detail sediment volume model from which sediment transport can be monitored and modeled.

  3. Acquisition and replay systems for direct-to-digital holography and holovision

    DOEpatents

    Thomas, Clarence E.; Hanson, Gregory R.

    2003-02-25

    Improvements to the acquisition and replay systems for direct-to-digital holography and holovision are described. A method of recording an off-axis hologram includes: splitting a laser beam into an object beam and a reference beam; reflecting the reference beam from a reference beam mirror; reflecting the object beam from an illumination beamsplitter; passing the object beam through an objective lens; reflecting the object beam from an object; focusing the reference beam and the object beam at a focal plane of a digital recorder to form an off-axis hologram; digitally recording the off-axis hologram; and transforming the off-axis hologram in accordance with a Fourier transform to obtain a set of results. A method of writing an off-axis hologram includes: passing a laser beam through a spatial light modulator; and focusing the laser beam at a focal plane of a photorefractive crystal to impose a holographic diffraction grating pattern on the photorefractive crystal. A method of replaying an off-axis hologram includes: illuminating a photorefractive crystal having a holographic diffraction grating with a replay beam.

  4. Direct to Implant Reconstruction in Nipple Sparing Mastectomy: Patient Selection by Preoperative Digital Mammogram

    PubMed Central

    Angrigiani, Claudio H.; Hammond, Dennis C.; Nava, Maurizio B.; Gonzalez, Eduardo G.; Dorr, Julio C.; Gercovich, Gustavo F.; Rocco, Nicola; Rostagno, Roman L.

    2017-01-01

    Background: Digital mammography clearly distinguishes gland tissue density from the overlying nonglandular breast tissue coverage, which corresponds to the existing tissue between the skin and the superficial layer of the fascia superficialis surrounding the gland (i.e., dermis and subcutaneous fat). Preoperative digital imaging can determine the thickness of this breast tissue coverage, thus facilitating planning and reducing the rate of necrotic complications after direct to implant (DTI) reconstruction in nipple sparing mastectomy (NSM). Methods: Thirty NSMs in 22 patients with type 3 tissue coverage (subcutaneous tissue thickness of 2 cm or more) were selected for DTI reconstruction after NSM to evaluate immediate skin flap/nipple areola complex ischemic complications and patient satisfaction. Results: We experienced no wound healing problems or ischemic complications immediately after surgery in our population. Only 1 seroma was observed as a short-term complication. Quality of life and patients’ satisfaction level were optimal at 3 and 6 months follow-up, respectively. The aesthetic results have been evaluated as good/excellent in all cases. Conclusions: DTI immediate reconstruction with silicone implants following NSM appears to be a safe option in selected cases with enough tissue coverage, also providing a high level of patient satisfaction. The possibility of selecting cases for this procedure according to the preoperative digital mammogram showing more than 2 cm of superficial tissues thickness may help reducing the risk of immediate ischemic complications. PMID:28740781

  5. Optimized setup for integral refractive index direct determination applying digital holographic microscopy by reflection and transmission

    NASA Astrophysics Data System (ADS)

    Frómeta, M.; Moreno, G.; Ricardo, J.; Arias, Y.; Muramatsu, M.; Gomes, L. F.; Palácios, G.; Palácios, F.; Velázquez, H.; Valin, J. L.; Ramirez Q, L.

    2017-03-01

    In this paper the integral refractive index of a microscopic sample was directly measured by applying Digital Holographic Microscopy (DHM) capturing transmission and reflection holograms simultaneously, of the same sample's region, using Mach-Zehnder and Michelson micro interferometers for transmission and reflection holograms capture and modeling the 3D sample in a medium of known refractive index nm. The system was calibrated using standard polystyrene sphere immersed in water with known diameter and refractive index, and the method was applied for erythrocyte integral refractive index determination. The results are in accordance with predicted, the measurements error of the order of ± 0.005 in absolute values.

  6. Complex object wave direct extraction method in off-axis digital holography.

    PubMed

    Kim, Daesuk; Magnusson, Robert; Jin, Moonseob; Lee, Jaejong; Chegal, Won

    2013-02-11

    Off-axis digital holography generally uses a 2D-FFT based spatial filtering method to extract the complex object wave from an off-axis hologram. In this paper, we describe a novel single exposure complex object wave extraction method which can provide a faster solution than the FFT based spatial filtering approach while maintaining the reconstructed phase image quality. And also, we show that the proposed direct filtering scheme can provide more robust filtering capability to the off-axis spatial carrier frequency variation than the spatial filtering method.

  7. Direct to Digital Holography for Semiconductor Wafer Defect Detection and Review

    SciTech Connect

    ThomasJr., C. E.; Bahm, Tracy M.; Baylor, Larry R; Bingham, Philip R.; Burns, Steven W.; Chidley, Matthew D; Dai, Xiaolong; Delahanty, Robert J.; Doti, Christopher J.; El-Khashab, Ayman; Fisher, Robert L.; Gilbert, Judd M.; Cui, Hongtao; Goddard Jr, James Samuel; Hanson, Gregory R; Hickson, Joel D.; Hunt, Martin A.; Hylton, Kathy W; John, George C.; Jones, Michael L.; McDonald, Kenneth R.; Mayo, Michael W.; McMackin, Ian; Patek, David; Price, John H.; Rasmussen, David A; Schaefer, Louis J.; Scheidt, Thomas R.; Schulze, Mark A.; Schumaker, Philip D.; Shen, Bichuan; Smith, Randall G.; Su, Allen N.; Tobin Jr, Kenneth William; Usry, William R.; Voelkl, Edgar; Weber, Karsten S.; Jones, Paul G.; Owen, Robert W.

    2002-01-01

    A method for recording true holograms (not holographic interferometry) directly to a digital video medium in a single image has been invented. This technology makes the amplitude and phase for every pixel of the target object wave available. Since phase is proportional to wavelength, this makes high-resolution metrology an implicit part of the holographic recording. Measurements of phase can be made to one hundredth or even one thousandth of a wavelength, so the technology is attractive for finding defects on semiconductor wafers, where feature sizes are now smaller than the wavelength of even deep ultra-violet light.

  8. Comparisons of jitter, shimmer, and signal-to-noise ratio from directly digitized versus taped voice samples.

    PubMed

    Gelfer, M P; Fendel, D M

    1995-12-01

    The purpose of this study was to compare jitter, shimmer, and signal-to-noise ratio (SNR) measures obtained from tape-recorded samples with the same measures made on directly digitized voice samples, with use of the CSpeech acoustic analysis program. Subjects included 30 young women who phonated the vowel /a/ at a comfortable pitch and loudness level. Voice samples were simultaneously recorded and digitized, and the resulting perturbation measures for the two conditions were compared. Results indicated that there were small but statistically significant differences between percent jitter, percent shimmer, and SNR calculated from taped samples compared with the same measures calculated from directly digitized samples. It was concluded that direct digitization for clinical measures of vocal perturbation was most desirable, but that taped samples could be used, if necessary, with some caution.

  9. Directional MTF measurement using sphere phantoms for a digital breast tomosynthesis system

    NASA Astrophysics Data System (ADS)

    Lee, Changwoo; Baek, Jongduk

    2015-03-01

    The digital breast tomosynthesis (DBT) has been widely used as a diagnosis imaging modality of breast cancer because of potential for structure noise reduction, better detectability, and less breast compression. Since 3D modulation transfer function (MTF) is one of the quantitative metrics to assess the spatial resolution of medical imaging systems, it is very important to measure 3D MTF of the DBT system to evaluate the resolution performance. In order to do that, Samei et al. used sphere phantoms and applied Thornton's method to the DBT system. However, due to the limitation of Thornton's method, the low frequency drop, caused by the limited data acquisition angle and reconstruction filters, was not measured correctly. To overcome this limitation, we propose a Richardson-Lucy (RL) deconvolution based estimation method to measure the directional MTF. We reconstructed point and sphere objects using FDK algorithm within a 40⁰ data acquisition angle. The ideal 3D MTF is obtained by taking Fourier transform of the reconstructed point object, and three directions (i.e., fx-direction, fy-direction, and fxy-direction) of the ideal 3D MTF are used as a reference. To estimate the directional MTF, the plane integrals of the reconstructed and ideal sphere object were calculated and used to estimate the directional PSF using RL deconvolution technique. Finally, the directional MTF was calculated by taking Fourier transform of the estimated PSF. Compared to the previous method, the proposed method showed a good agreement with the ideal directional MTF, especially at low frequency regions.

  10. [Therapeutic instrument for brain circulation function on the basis of direct digital synthesis technology].

    PubMed

    Li, Qiang; Gan, Minliang

    2005-02-01

    Electricity can stimulate cerebral fastigial nucleus to increase regional cerebral blood flow (rCBF) and narrow the volume of infarct, therefore its effect on ischemic brain disorder may be helpful. The therapeutic instrument for brain circulation function based on direct digital synthesis (DDS) technology uses the domestic newest scientific findings and others in foreign countries. Adopting the DDS technology directly, it institutes safe and efficacious treatment. Through pasting the electrodes on body surface, the non-invasive instrument introduces electric current to cerebral fastigial nucleus (FN) and hence it improves the state of brain blood supply and nerve conduction, increases cerebral blood flow, reduces the number of necrotic neurons in the district of penumbra, and mitigates brain edema. Consequently, it improves the function of brain circulation.

  11. Replacing single-view mediolateral oblique (MLO) digital mammography (DM) with synthesized mammography (SM) with digital breast tomosynthesis (DBT) images: Comparison of the diagnostic performance and radiation dose with two-view DM with or without MLO-DBT.

    PubMed

    Kang, Hyo-Jin; Chang, Jung Min; Lee, Joongyub; Song, Sung Eun; Shin, Sung Ui; Kim, Won Hwa; Bae, Min Sun; Moon, Woo Kyung

    2016-11-01

    To evaluate the diagnostic performance and radiation dose of single view cranio-caudal (CC) digital mammography (DM) plus mediolateral oblique (MLO) digital breast tomosynthesis (DBT) combined with synthesized mammography (SM) in comparison with two-view DM with or without DBT. This study was approved by our institutional review board, and informed consent was obtained from 130 women. Paired two-view DM and single MLO-DBT with SM images were acquired, and four independent retrospective reading sessions of different combinations of DM, SM and DBT were performed for the presence of malignant tumors using jackknife alternative free-response receiver operator curve (JAFROC) methods. The diagnostic performances and average glandular dose (AGD) were compared between different combinations of DM, SM and DBT. Of 159 lesions in 130 patients, 27 were malignant. When using MLO-DBT with SM instead of MLO-DM, a significantly higher sensitivity (P=0.016) and specificity (P=0.012) were noted than with two-view DM, and comparable figure of merit (FOM), sensitivity, and specificity to two-view DM with DBT were noted. The mean AGD of CC-DM plus MLO-DBT with SM was 5.78mGy±1.06 per patient, which was significantly lower than that with two-view DM with MLO-DBT (8.45mGy±1.32; P <0.001) and slightly higher than that with two-view DM (5.30mGy±0.63). The combined use of CC-DM plus MLO-DBT with SM showed higher sensitivity and specificity to two-view DM with a smaller AGD increment and comparable diagnostic performance to that of two-view DM with MLO-DBT with a significantly lower mean AGD. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  12. [FeIII(SR)4]1− Complexes Can Be Synthesized By the Direct Reaction of Thiolates With FeCl3**

    PubMed Central

    Chang, Sechin; Koch, Stephen A.

    2007-01-01

    It is shown that the previously characterized [FeIII(SR)4]1− (R= Et, i-Pr, Ph) complexes can be synthesized by the direct reaction of 4 equiv of LiSR with FeCl3 in DMF solution. [FeIII(SR)4]1− complexes are synthetic analogs for the [FeIII(S-Cys)4] center in rubredoxin proteins. PMID:17723243

  13. [FeIII(SR)4]1- Complexes can be Synthesized by the Direct Reaction of Thiolates with FeCl3

    USDA-ARS?s Scientific Manuscript database

    It is shown that the previously characterized [FeIII(SR)4]1- (R=Et, i-Pr, Ph) complexes can be synthesized by the direct reaction of 4 equivalents of LiSR with FeCl3 in DMF solution. [FeIII(SR)4]1- complexes are synthetic analogs for the [FeIII(S-Cystein)4] center in rubredoxin proteins....

  14. SYNTHESIZER CONTROLLED BEAM TRANSFER FROM THE AGS TO RHIC.

    SciTech Connect

    DELONG,J.; BRENNAN,J.M.; FISCHER,W.; HAYES,T.; SMITH,K.; VALENTINO,S.

    2001-06-18

    To ensure minimal losses and to preserve longitudinal emittance, beam is transferred from the AGS to the RHIC bunch to bucket. This requires precision frequency and phase control for synchronization and kicker timing. The required precision is realized with a set of Direct Digital Synthesizers. Each synthesizer can be frequency and phase modulated to align the AGS bunch to the target bucket in the RHIC phase.

  15. Scalable Total Syntheses of N-Linked Tryptamine Dimers by Direct Indole-Aniline Coupling: Psychotrimine and Kapakahines B & F

    PubMed Central

    Newhouse, Timothy; Lewis, Chad A.; Eastman, Kyle J.; Baran, Phil S.

    2010-01-01

    This report details the invention of a method to enable syntheses of psychotrimine, 1, and the kapakahines F and B, 2 & 3, on a gram scale and in a minimum number of steps. Mechanistic inquiries are presented for the key enabling quaternization of indole at the C3 position by electrophilic attack of an activated aniline species. Excellent chemo-, regio-, and diastereoselectivities are observed for reactions with o-iodoaniline, an indole cation equivalent. Additionally, the scope of this reaction is broad with respect to the tryptamine and aniline components. The anti-cancer profiles of psychotrimine, 1, and kapakahines F and B, 2 & 3, have also been evaluated. PMID:20426477

  16. Surface-modification-directed controlled adsorption of serum albumin onto magnetite nanocuboids synthesized in a gel-diffusion technique.

    PubMed

    Borah, Ballav Moni; Saha, Bedabrata; Dey, Sandeep Kumar; Das, Gopal

    2010-09-01

    Magnetite nanocuboids have been synthesized via gel-diffusion technique in agarose gel. Here, the agarose gel matrix has been used as an organic template for formation and growth modification of magnetite. Gel mineralization mimics the membrane-based biomineralization, controls the diffusion process and gives the micro/nano environment for the crystal growth. We also attempt to understand the influence of different surface modifications of synthesized magnetite nanocuboids on protein interaction. For this purpose, magnetite particles were coated with trimesic acid (benzene-1,3,5-tricarboxylic acid) and stearic acid, which generates a hydrophilic and a hydrophobic modified surface, respectively. We report controlled adsorption behavior of bovine serum albumin (BSA) by surface modification of magnetite nanocuboids with different functional groups. The adsorption capacity of BSA increases on trimesic acid-coated surfaces compared to bare magnetite surfaces, while it decreases on stearic acid-coated surfaces. In situ fluorescence spectroscopy has been used to analyze the tertiary protein structure in the adsorbed state on these three surfaces. Partial unfolding in the tertiary structure of BSA was observed upon adsorption onto bare magnetite surfaces. On trimesic acid-coated surfaces, tertiary unfolding of BSA was greater than on bare magnetite surfaces, while BSA undergoes minor tertiary structural change on stearic acid-coated surfaces. Copyright 2010 Elsevier Inc. All rights reserved.

  17. Digital direct electron imaging of energy-filtered electron backscatter diffraction patterns

    NASA Astrophysics Data System (ADS)

    Vespucci, S.; Winkelmann, A.; Naresh-Kumar, G.; Mingard, K. P.; Maneuski, D.; Edwards, P. R.; Day, A. P.; O'Shea, V.; Trager-Cowan, C.

    2015-11-01

    Electron backscatter diffraction is a scanning electron microscopy technique used to obtain crystallographic information on materials. It allows the nondestructive mapping of crystal structure, texture, and strain with a lateral and depth resolution on the order of tens of nanometers. Electron backscatter diffraction patterns (EBSPs) are presently acquired using a detector comprising a scintillator coupled to a digital camera, and the crystallographic information obtainable is limited by the conversion of electrons to photons and then back to electrons again. In this article we will report the direct acquisition of energy-filtered EBSPs using a digital complementary metal-oxide-semiconductor hybrid pixel detector, Timepix. We show results from a range of samples with different mass and density, namely diamond, silicon, and GaN. Direct electron detection allows the acquisition of EBSPs at lower (≤5 keV) electron beam energies. This results in a reduction in the depth and lateral extension of the volume of the specimen contributing to the pattern and will lead to a significant improvement in lateral and depth resolution. Direct electron detection together with energy filtering (electrons having energy below a specific value are excluded) also leads to an improvement in spatial resolution but in addition provides an unprecedented increase in the detail in the acquired EBSPs. An increase in contrast and higher-order diffraction features are observed. In addition, excess-deficiency effects appear to be suppressed on energy filtering. This allows the fundamental physics of pattern formation to be interrogated and will enable a step change in the use of electron backscatter diffraction (EBSD) for crystal phase identification and the mapping of strain. The enhancement in the contrast in high-pass energy-filtered EBSD patterns is found to be stronger for lighter, less dense materials. The improved contrast for such materials will enable the application of the EBSD

  18. Optic disc detection from normalized digital fundus images by means of a vessels' direction matched filter.

    PubMed

    Youssif, A R; Ghalwash, A Z; Ghoneim, A R

    2008-01-01

    Optic disc (OD) detection is a main step while developing automated screening systems for diabetic retinopathy. We present in this paper a method to automatically detect the position of the OD in digital retinal fundus images. The method starts by normalizing luminosity and contrast through out the image using illumination equalization and adaptive histogram equalization methods respectively. The OD detection algorithm is based on matching the expected directional pattern of the retinal blood vessels. Hence, a simple matched filter is proposed to roughly match the direction of the vessels at the OD vicinity. The retinal vessels are segmented using a simple and standard 2-D Gaussian matched filter. Consequently, a vessels direction map of the segmented retinal vessels is obtained using the same segmentation algorithm. The segmented vessels are then thinned, and filtered using local intensity, to represent finally the OD-center candidates. The difference between the proposed matched filter resized into four different sizes, and the vessels' directions at the surrounding area of each of the OD-center candidates is measured. The minimum difference provides an estimate of the OD-center coordinates. The proposed method was evaluated using a subset of the STARE project's dataset, containing 81 fundus images of both normal and diseased retinas, and initially used by literature OD detection methods. The OD-center was detected correctly in 80 out of the 81 images (98.77%). In addition, the OD-center was detected correctly in all of the 40 images (100%) using the publicly available DRIVE dataset.

  19. Exploratory Study of Rural Physicians' Self-Directed Learning Experiences in a Digital Age.

    PubMed

    Curran, Vernon; Fleet, Lisa; Simmons, Karla; Ravalia, Mohamed; Snow, Pamela

    2016-01-01

    The nature and characteristics of self-directed learning (SDL) by physicians has been transformed with the growth in digital, social, and mobile technologies (DSMTs). Although these technologies present opportunities for greater "just-in-time" information seeking, there are issues for ensuring effective and efficient usage to compliment one's repertoire for continuous learning. The purpose of this study was to explore the SDL experiences of rural physicians and the potential of DSMTs for supporting their continuing professional development (CPD). Semistructured interviews were conducted with a purposive sample of rural physicians. Interview data were transcribed verbatim and analyzed using NVivo analytical software and thematic analysis. Fourteen (N = 14) interviews were conducted and key thematic categories that emerged included key triggers, methods of undertaking SDL, barriers, and supports. Methods and resources for undertaking SDL have evolved considerably, and rural physicians report greater usage of mobile phones, tablets, and laptop computers for updating their knowledge and skills and in responding to patient questions/problems. Mobile technologies, and some social media, can serve as "triggers" in instigating SDL and a greater usage of DSMTs, particularly at "point of care," may result in higher levels of SDL. Social media is met with some scrutiny and ambivalence, mainly because of the "credibility" of information and risks associated with digital professionalism. DSMTs are growing in popularity as a key resource to support SDL for rural physicians. Mobile technologies are enabling greater "point-of-care" learning and more efficient information seeking. Effective use of DSMTs for SDL has implications for enhancing just-in-time learning and quality of care. Increasing use of DSMTs and their new effect on SDL raises the need for reflection on conceptualizations of the SDL process. The "digital age" has implications for our CPD credit systems and the roles

  20. Fused off-axis object illumination direct-to-digital holography with a plurality of illumination sources

    DOEpatents

    Price, Jeffery R.; Bingham, Philip R.

    2005-11-08

    Systems and methods are described for rapid acquisition of fused off-axis illumination direct-to-digital holography. A method of recording a plurality of off-axis object illuminated spatially heterodyne holograms, each of the off-axis object illuminated spatially heterodyne holograms including spatially heterodyne fringes for Fourier analysis, includes digitally recording, with a first illumination source of an interferometer, a first off-axis object illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; and digitally recording, with a second illumination source of the interferometer, a second off-axis object illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis.

  1. Direct Manufacturing of CubeSat Using 3-D Digital Printer and Determination of its Mechanical Properties

    DTIC Science & Technology

    2010-12-01

    mechanical properties (i.e. strength and elastic modulus) of samples fabricated from a 3-D digital printer as a function of processing parameters (2) to...geometry is brought into the 3D printer software application and rotated for the desired build orientation. The software then slices horizontal build...Arlington, VA 22203-1714 Direct Manufacturing of CubeSat Using 3-D Digital Printer and Determination of Its Mechanical Properties

  2. A firmware-defined digital direct-sampling NMR spectrometer for condensed matter physics.

    PubMed

    Pikulski, M; Shiroka, T; Ott, H-R; Mesot, J

    2014-09-01

    We report on the design and implementation of a new digital, broad-band nuclear magnetic resonance (NMR) spectrometer suitable for probing condensed matter. The spectrometer uses direct sampling in both transmission and reception. It relies on a single, commercially-available signal processing device with a user-accessible field-programmable gate array (FPGA). Its functions are defined exclusively by the FPGA firmware and the application software. Besides allowing for fast replication, flexibility, and extensibility, our software-based solution preserves the option to reuse the components for other projects. The device operates up to 400 MHz without, and up to 800 MHz with undersampling, respectively. Digital down-conversion with ±10 MHz passband is provided on the receiver side. The system supports high repetition rates and has virtually no intrinsic dead time. We describe briefly how the spectrometer integrates into the experimental setup and present test data which demonstrates that its performance is competitive with that of conventional designs.

  3. A firmware-defined digital direct-sampling NMR spectrometer for condensed matter physics

    SciTech Connect

    Pikulski, M. Shiroka, T.; Ott, H.-R.; Mesot, J.

    2014-09-15

    We report on the design and implementation of a new digital, broad-band nuclear magnetic resonance (NMR) spectrometer suitable for probing condensed matter. The spectrometer uses direct sampling in both transmission and reception. It relies on a single, commercially-available signal processing device with a user-accessible field-programmable gate array (FPGA). Its functions are defined exclusively by the FPGA firmware and the application software. Besides allowing for fast replication, flexibility, and extensibility, our software-based solution preserves the option to reuse the components for other projects. The device operates up to 400 MHz without, and up to 800 MHz with undersampling, respectively. Digital down-conversion with ±10 MHz passband is provided on the receiver side. The system supports high repetition rates and has virtually no intrinsic dead time. We describe briefly how the spectrometer integrates into the experimental setup and present test data which demonstrates that its performance is competitive with that of conventional designs.

  4. Direct Measurement of Mammographic X-Ray Spectra with a Digital CdTe Detection System

    PubMed Central

    Abbene, Leonardo; Gerardi, Gaetano; Principato, Fabio; Sordo, Stefano Del; Raso, Giuseppe

    2012-01-01

    In this work we present a detection system, based on a CdTe detector and an innovative digital pulse processing (DPP) system, for high-rate X-ray spectroscopy in mammography (1–30 keV). The DPP system performs a height and shape analysis of the detector pulses, sampled and digitized by a 14-bit, 100 MHz ADC. We show the results of the characterization of the detection system both at low and high photon counting rates by using monoenergetic X-ray sources and a nonclinical X-ray tube. The detection system exhibits excellent performance up to 830 kcps with an energy resolution of 4.5% FWHM at 22.1 keV. Direct measurements of clinical molybdenum X-ray spectra were carried out by using a pinhole collimator and a custom alignment device. A comparison with the attenuation curves and the half value layer values, obtained from the measured and simulated spectra, from an ionization chamber and from a solid state dosimeter, also shows the accuracy of the measurements. These results make the proposed detection system a very attractive tool for both laboratory research, calibration of dosimeters and advanced quality controls in mammography. PMID:22969406

  5. Reference-free direct digital lock-in method and apparatus

    NASA Technical Reports Server (NTRS)

    Henry, James E. (Inventor); Leonard, John A. (Inventor)

    2000-01-01

    A reference-free direct digital lock-in system (RDDL 10) has a first input coupled to a periodic electrical signal and an output for outputting an indication of a magnitude of a desired periodic signal component. The RDDL also has a second input for receiving a signal (9) that specifies a reference period value, and operates to autonomously generate a lock-in reference signal having a specified period and a phase that is adjusted to maximize a magnitude of the outputted desired periodic signal component. In an embodiment of a measurement system that includes the RDDL 10 an optical source provides a chopped light beam having wavelengths within a predetermined range of wavelengths, and the periodic electrical signal is generated by at least one photodetector that is illuminated by the chopped light beam. In this embodiment the measurement system characterizes, for at least one wavelength of light that is generated by the optical source, a spectral response of the at least one photodetector. The RDDL can operate in nonreal-time upon previously generated and stored digital equivalent values of the periodic electrical signal or signals.

  6. New ways to synthesize lead sulfide nanosheets-substituted alkanes direct the growth of 2D nanostructures.

    PubMed

    Bielewicz, Thomas; Klein, Eugen; Klinke, Christian

    2016-09-02

    Two-dimensional colloidal nanosheets represent very attractive optoelectronic materials. They combine good lateral conductivity with solution-processability and geometry-tunable electronic properties. In the case of PbS nanosheets, so far synthesis has been driven by the addition of chloroalkanes as coligands. Here, we demonstrate how to synthesize two-dimensional lead sulfide nanostructures using other halogen alkanes and primary amines. Further, we show that at a reaction temperature of 170 °C a coligand is not even necessary and the only ligand, oleic acid, controls the anisotropic growth of the two-dimensional structures. Also, using thiourea as a sulfide source, nanosheets with lateral dimensions of over 10 μm are possible.

  7. New ways to synthesize lead sulfide nanosheets—substituted alkanes direct the growth of 2D nanostructures

    NASA Astrophysics Data System (ADS)

    Bielewicz, Thomas; Klein, Eugen; Klinke, Christian

    2016-09-01

    Two-dimensional colloidal nanosheets represent very attractive optoelectronic materials. They combine good lateral conductivity with solution-processability and geometry-tunable electronic properties. In the case of PbS nanosheets, so far synthesis has been driven by the addition of chloroalkanes as coligands. Here, we demonstrate how to synthesize two-dimensional lead sulfide nanostructures using other halogen alkanes and primary amines. Further, we show that at a reaction temperature of 170 °C a coligand is not even necessary and the only ligand, oleic acid, controls the anisotropic growth of the two-dimensional structures. Also, using thiourea as a sulfide source, nanosheets with lateral dimensions of over 10 μm are possible.

  8. Infrared Femtosecond Laser Direct-Writing Digital Volume Gratings in Fused Silica

    NASA Astrophysics Data System (ADS)

    Wang, Ying; Li, Yu-Hua; Lu, Pei-Xiang

    2010-04-01

    We demonstrate that digital volume gratings can be fabricated in fused silica glass conveniently by direct femtosecond laser writing. The diffraction efficiencies of volume gratings can be essentially modulated by simply stacking and offsetting the unit structure. A series of volume gratings, which have the pitches of 5 μm and the size of 1 mm × 1 mm, have been fabricated with the writing speed of 500 μm/s, with which the processing period of each grating layer could be reduced to several minutes with a 1-kHz femtosecond laser system. Results show that the power spectrum of the diffracted waves of the volume gratings are dependent on the layer gap and layer offsetting.

  9. Direct Digital Synthesis Chirped Pulse Microwave Spectrometers for the Classroom and Research

    NASA Astrophysics Data System (ADS)

    Blake, Geoffrey; Carroll, Brandon; Finneran, Ian A.

    2015-06-01

    By combining the rapid development in direct digital synthesis circuitry and Field Programmable Gate Arrays (FPGAs) coupled to fast A/D samplers, it is possible to construct high performance chirped pulse microwave spectrometers suitable for gas-phase rotational spectroscopy experiments in undergraduate physical chemistry labs as well as graduate level research. The technology is highly tailorable, and sufficiently robust that extensive experimentation is feasible in the teaching environment. The time domain nature of the experiment has strong ties to concepts in Nuclear Magnetic Resonance (NMR) widely discussed in undergraduate curricula, and the software environment for the instrument control and spectral assignment can be integrated with ab initio quantum chemistry predictions of molecular structure and dynamics.

  10. Digital baseband predistortion for SSII cancellation in EAM-based direct-detection OFDM systems

    NASA Astrophysics Data System (ADS)

    Yang, Pengfei; Shi, Hu; Chen, Xue

    2017-01-01

    To increase the available bandwidth of electro-absorption modulator (EAM)-based direct-detection orthogonal frequency division multiplexing (DD-OFDM) systems, which suffers from dispersion- and chirp-induced power fading, the multiband subcarrier allocation scheme and adaptive modulation formats are adopted. However, the subcarrier-to-subcarrier intermixing interference (SSII) would degrade signal-to-noise ratio on the increased bandwidth and become a bottleneck of the multiband systems. In this paper, a novel digital baseband predistortion is proposed to minimize the penalty of SSII. The experimental results show that a 30 Gbps EAM-based DD-OFDM system with the proposed technique could improve 3 dB receiver sensitivity compared with the system without the technique over 100 km long single mode fiber transmission and only decreases 1.0 dB in comparison with the back-to-back situation.

  11. Early experience with digital advance care planning and directives, a novel consumer-driven program

    PubMed Central

    Yang, Zhiyong; Spivey, Christy; Boardman, Bonnie; Courtney, Maureen

    2016-01-01

    Barriers to traditional advance care planning (ACP) and advance directive (AD) creation have limited the promise of ACP/AD for individuals and families, the healthcare team, and society. Our objectives were to determine the results of a digital ACP/AD through which consumers create, store, locate, and retrieve their ACP/AD at no charge and with minimal physician involvement, and the ACP/AD can be integrated into the electronic health record. The authors chose 900 users of MyDirectives, a digital ACP/AD tool, to achieve proportional representation of all 50 states by population size and then reviewed their responses. The 900 participants had an average age of 50.8 years (SD = 16.6); 84% of the men and 91% of the women were in self-reported good health when signing their ADs. Among the respondents, 94% wanted their physicians to consult a supportive and palliative care team if they were seriously ill; nearly 85% preferred cessation of life-sustaining treatments during their final days; 76% preferred to spend their final days at home or in a hospice; and 70% would accept attempted cardiopulmonary resuscitation in limited circumstances. Most respondents wanted an autopsy under certain conditions, and 62% wished to donate their organs. In conclusion, analysis of early experience with this ACP/AD platform demonstrates that individuals of different ages and conditions can engage in an interrogatory process about values, develop ADs that are more nuanced than traditional paper-based ADs in reflecting those values, and easily make changes to their ADs. Online ADs have the potential to remove barriers to ACP/AD and thus further improve patient-centered end-of-life care. PMID:27365867

  12. Image quality of a prototype direct conversion detector for digital mammography

    NASA Astrophysics Data System (ADS)

    Mainprize, James G.; Ford, Nancy L.; Yin, Shi; Tumer, Tumay O.; Yaffe, Martin J.

    1999-05-01

    A digital mammography system in which the x-ray sensitive device is a solid-state direct conversion detector is under development. This detector is a 1 mm thick silicon photodiode array hybridized to a CCD read-out, with a 50 micrometer pixel pitch. The detector is designed to be used in a slot-scanned system using time-delay integration (TDI) for signal acquisition. To handle the large signal generated in the photodiode, a novel read-out technique was used, in which charge was integrated 'on-chip' over a small number of rows, and the output of each of these sections was digitally summed 'off-chip' to produce the total integrated signal for each pixel in the image. This two-stage integration process not only allows easy acquisition of large signals, it effectively increases bit depth from 12 bits (for a single section) to approximately 16 (for the total integrated signal). The image quality of the device has been measured and compared to predictions based on cascaded linear systems theory. The resolution of the new detector was determined from the modulation transfer function (MTF) which was obtained from over-sampled edge spread functions (ESF). The ESF was measured in both the scan and slot directions from four repeated images of a tantalum edge. Noise power spectra (NPS) were determined from 40 repeated flat-field images at each of several x-ray exposures. By combining the MTF and NPS measurements, the detective quantum efficiency (DQE) was also determined. The MTF in the non-scanned direction was found to greater than 20% at 10 mm-1 and slightly lower in the scanned direction (approximately equals 10% at 10 mm-1). In all cases, the DQE was at least comparable to film-screen mammography receptors. The DQE at 120 mR detector exposure at zero spatial frequency ranged from 0.4 to 0.6 depending on the sample tested. Electronic noise was fairly low, contributing to less than plus or minus 7 ADU (out of a possible 98304 ADU). Future work will involve re-designing the

  13. Evidence for direct cellular protective effect of PL-10 substances (synthesized parts of body protection compound, BPC) and their specificity to gastric mucosal cells.

    PubMed

    Bódis, B; Karádi, O; Németh, P; Dohoczky, C; Kolega, M; Mózsik, G

    1997-01-01

    The direct gastric mucosal cellular effect of four PL-10 substances (a synthesized part of human body protection compound, BPC containing 14 or 15 amino acids) was studied on freshly isolated rat gastric mucosal cells and on a mouse myeloma cell line (Sp2/0-Ag14) in an ethanol-induced cell injury model. The examined substances were not toxic for the cells. Two of them proved to be significantly protective against the direct cellular damaging effect of ethanol (PL 10.1.15AK-3 in 5 microg/ml dose and PL 10.1.AK14-2 dose-dependently, ED50=50 ng/ml) on gastric mucosal cells. This cytoprotective effect was failured on mouse myeloma cells. Based on these results a part of the in vivo protection induced by BPC seems to be a direct cellular protective effect to gastric mucosal cells.

  14. Toward direct light-to-digital conversion using a pulse-driven hybrid MOS-PN photodetector.

    PubMed

    Sallin, Denis; Koukab, Adil; Kayal, Maher

    2015-02-15

    In this Letter, a direct light-to-digital converter based on an MOS-PN photodetector driven by pulsed voltage is presented. The objective is to avoid any analog-to-digital or time-to-digital conversion and, thereby, to pave the way for a new generation of fully digital imaging sensors with reduced complexity, area, and power consumption. Moreover, the pulsed voltage operation allows for a significant reduction of the dark level. The concept is validated by a theoretical study and TCAD simulations. A first prototype fabricated in 0.18 μm CMOS technology is presented. The experimental results under various light conditions show that the pulsed voltage improves the light sensitivity by several orders of magnitude.

  15. Development of environmentally friendly syntheses: use of enzymes and biomimetic systems for the direct carboxylation of organic substrates.

    PubMed

    Aresta, Michele; Dibenedetto, Angela

    2002-04-01

    Carboxylation reactions widely occur in nature by the direct use of carbon dioxide or hydrogen carbonate and are mediated by enzymes, which may or may not have a metal as an active center. Such direct carboxylation reactions have found only very few applications for synthetic purposes at industrial level. In this paper we review a part of the work we have done on the use of carbon dioxide and describe: (i) the use of a carboxylation enzyme for the conversion of phenol into 4-OH benzoic acid; and (ii) the potential of biomimetic mixed anhydrides for the synthesis of compounds of industrial interest. The enzymatic production of acetic acid from carbon dioxide is compared with known and new transition metal catalyzed reactions that are fully biomimetic.

  16. Covert digital manipulation of vocal emotion alter speakers' emotional states in a congruent direction.

    PubMed

    Aucouturier, Jean-Julien; Johansson, Petter; Hall, Lars; Segnini, Rodrigo; Mercadié, Lolita; Watanabe, Katsumi

    2016-01-26

    Research has shown that people often exert control over their emotions. By modulating expressions, reappraising feelings, and redirecting attention, they can regulate their emotional experience. These findings have contributed to a blurring of the traditional boundaries between cognitive and emotional processes, and it has been suggested that emotional signals are produced in a goal-directed way and monitored for errors like other intentional actions. However, this interesting possibility has never been experimentally tested. To this end, we created a digital audio platform to covertly modify the emotional tone of participants' voices while they talked in the direction of happiness, sadness, or fear. The result showed that the audio transformations were being perceived as natural examples of the intended emotions, but the great majority of the participants, nevertheless, remained unaware that their own voices were being manipulated. This finding indicates that people are not continuously monitoring their own voice to make sure that it meets a predetermined emotional target. Instead, as a consequence of listening to their altered voices, the emotional state of the participants changed in congruence with the emotion portrayed, which was measured by both self-report and skin conductance level. This change is the first evidence, to our knowledge, of peripheral feedback effects on emotional experience in the auditory domain. As such, our result reinforces the wider framework of self-perception theory: that we often use the same inferential strategies to understand ourselves as those that we use to understand others.

  17. Digital Direct-to-Consumer Advertising: A Perfect Storm of Rapid Evolution and Stagnant Regulation

    PubMed Central

    Mackey, Tim K.

    2016-01-01

    The adoption and use of digital forms of direct-to-consumer advertising (also known as "eDTCA") is on the rise. At the same time, the universe of eDTCA is expanding, as technology on Internet-based platforms continues to evolve, from static websites, to social media, and nearly ubiquitous use of mobile devices. However, little is known about how this unique form of pharmaceutical marketing impacts consumer behavior, public health, and overall healthcare utilization. The study by Kim analyzing US Food and Drug Administration (FDA) notices of violations (NOVs) and warning letters regarding online promotional activities takes us in the right direction, but study results raise as many questions as it does answers. Chief among these are unanswered concerns about the unique regulatory challenges posed by the "disruptive" qualities of eDTCA, and whether regulators have sufficient resources and oversight powers to proactively address potential violations. Further, the globalization of eDTCA via borderless Internet-based technologies raises larger concerns about the potential global impact of this form of health marketing unique to only the United States and New Zealand. Collectively, these challenges make it unlikely that regulatory science will be able to keep apace with the continued rapid evolution of eDTCA unless more creative policy solutions are explored. PMID:27239871

  18. Covert digital manipulation of vocal emotion alter speakers’ emotional states in a congruent direction

    PubMed Central

    Johansson, Petter; Hall, Lars; Segnini, Rodrigo; Mercadié, Lolita; Watanabe, Katsumi

    2016-01-01

    Research has shown that people often exert control over their emotions. By modulating expressions, reappraising feelings, and redirecting attention, they can regulate their emotional experience. These findings have contributed to a blurring of the traditional boundaries between cognitive and emotional processes, and it has been suggested that emotional signals are produced in a goal-directed way and monitored for errors like other intentional actions. However, this interesting possibility has never been experimentally tested. To this end, we created a digital audio platform to covertly modify the emotional tone of participants’ voices while they talked in the direction of happiness, sadness, or fear. The result showed that the audio transformations were being perceived as natural examples of the intended emotions, but the great majority of the participants, nevertheless, remained unaware that their own voices were being manipulated. This finding indicates that people are not continuously monitoring their own voice to make sure that it meets a predetermined emotional target. Instead, as a consequence of listening to their altered voices, the emotional state of the participants changed in congruence with the emotion portrayed, which was measured by both self-report and skin conductance level. This change is the first evidence, to our knowledge, of peripheral feedback effects on emotional experience in the auditory domain. As such, our result reinforces the wider framework of self-perception theory: that we often use the same inferential strategies to understand ourselves as those that we use to understand others. PMID:26755584

  19. Direct digital lateral cephalometry: the effects of JPEG compression on image quality.

    PubMed

    Wenger, N A; Tewson, D H T K; McDonald, F

    2006-07-01

    This study used an aluminium test object to assess the effect of the Joint Photographics Expert Group (JPEG) compression algorithm, on direct digital cephalometric image quality. The aluminium block of 15 steps, with 20 holes in each step was radiographed in a Planmeca Proline 2002 digital cephalometric machine with Dimaxis2 software. Six different JPEG compression ratios were used to capture the cephalometric images. These ratios were 60%, 70%, 80%, 90%, TOP QUALITY JPEG (TQJPEG 98%) and TIFF (uncompressed). The images were taken at 68 kV and 12 mA with a 7 s exposure. Six experienced observers viewed the monitor displayed images, which were presented randomly. This was repeated one month later. The number of holes detected by each observer was plotted against each compression ratio. Intra-observer and inter-observer reproducibility was calculated using the Mann-Whitney U-test. Differences between the compression ratios were assessed using a Kruskal-Wallis one-way analysis of variance. When comparing intra-observer reproducibility, it was found that there were only four of 36 comparisons that showed a statistically significant difference (Observer 1: 60% (P=0.004), TQJPEG (P=0.019); Observer 2: TIFF (P=0.005); Observer 3: 90% (P=0.007)). Statistically, there was no significant difference with inter-observer reproducibility. There was no statistically significant difference between the image quality obtained from each compression ratio. The results showed that JPEG compression does not have any effect on the perceptibility of landmarks in the aluminium test object used in this study.

  20. Digital Game Playing and Direct and Indirect Aggression in Early Adolescence: The Roles of Age, Social Intelligence, and Parent-Child Communication

    ERIC Educational Resources Information Center

    Wallenius, Marjut; Punamaki, Raija-Leena; Rimpela, Arja

    2007-01-01

    The roles of age, social intelligence and parent-child communication in moderating the association between digital game playing and direct and indirect aggression were examined in 478 Finnish 10- and 13-year-old schoolchildren based on self-reports. The results confirmed that digital game violence was directly associated with direct aggression,…

  1. Digital Game Playing and Direct and Indirect Aggression in Early Adolescence: The Roles of Age, Social Intelligence, and Parent-Child Communication

    ERIC Educational Resources Information Center

    Wallenius, Marjut; Punamaki, Raija-Leena; Rimpela, Arja

    2007-01-01

    The roles of age, social intelligence and parent-child communication in moderating the association between digital game playing and direct and indirect aggression were examined in 478 Finnish 10- and 13-year-old schoolchildren based on self-reports. The results confirmed that digital game violence was directly associated with direct aggression,…

  2. The alloying effect and AgCl-directing growth for synthesizing a trimetallic nanoring with improved SERS

    NASA Astrophysics Data System (ADS)

    Han, Shuhua; Zhou, Guangju; Fu, Yunzhi; Ma, Ying; Xu, Li; Zou, Chao; Chen, Wei; Yang, Yun; Huang, Shaoming

    2015-12-01

    We report the synthesis of high quality trimetallic Au/Ag/Pt nanorings (TAAPNs) by using Au/Ag alloy decahedra (AAAD) as templates. The alloying effect and AgCl-directing growth have been investigated in detail during the formation of TAAPN. It was found that the doping of Ag in AAAD changes the surrounding environment of Au atoms and decreases the oxidization reduction potential (ORP) of [AuCl2]-/Au because of the alloying effect, resulting in the dissolved O2 molecules that serve as an effective etchant for oxidizing Au to Au(i). Ascorbic acid (AA) and chloroplatinic acid (H2PtCl6) are weak acids which can accelerate the etching by increasing the concentration of H+. The AgCl selectively absorbs on {100} of the decahedra and induces the preferential deposition of H2PtCl6 here via their complexing interaction. AA reduces Pt(iv) and Ag(i) to atoms which grow on {100} facets. The formed Pt/Ag layer changes the etching direction from along [100] to [111] and generates the TAAPN. Besides, it has been noted that the TAAPNs exhibit good Surface Enhanced Raman Scattering (SERS) performance.We report the synthesis of high quality trimetallic Au/Ag/Pt nanorings (TAAPNs) by using Au/Ag alloy decahedra (AAAD) as templates. The alloying effect and AgCl-directing growth have been investigated in detail during the formation of TAAPN. It was found that the doping of Ag in AAAD changes the surrounding environment of Au atoms and decreases the oxidization reduction potential (ORP) of [AuCl2]-/Au because of the alloying effect, resulting in the dissolved O2 molecules that serve as an effective etchant for oxidizing Au to Au(i). Ascorbic acid (AA) and chloroplatinic acid (H2PtCl6) are weak acids which can accelerate the etching by increasing the concentration of H+. The AgCl selectively absorbs on {100} of the decahedra and induces the preferential deposition of H2PtCl6 here via their complexing interaction. AA reduces Pt(iv) and Ag(i) to atoms which grow on {100} facets. The formed

  3. A comparative cost analysis of digital fundus imaging and direct fundus examination for assessment of diabetic retinopathy.

    PubMed

    Gomez-Ulla, Francisco; Alonso, Florentina; Aibar, Beatriz; Gonzalez, Francisco

    2008-11-01

    The objective of this study was to compare the cost between two procedures for fundus examination in patients with diabetes. In our setting, two alternatives for fundus examination are available for patients with diabetes. In the first alternative, a digital image is taken with a nonmydriatic fundus camera when the patient is at the endocrinology consultation, and the image is then examined by an ophthalmologist. In the second alternative, a direct fundus examination is made by an ophthalmologist. We calculated the costs of both procedures from both Public Healthcare System (PHS) and patient perspectives using the official scales to compute personnel, consumables, capital cost of equipment, travel expenses, and time loss of the patient caused by attending the consultation. The first alternative (digital fundus image) required 2.69, 0.03, and 1.62 Euros per patient for personnel, consumables, and capital cost of the equipment, respectively. A direct fundus examination was needed in 31% of patients that had an additional cost of 0.97 Euros per patient for the PHS plus 14.97 Euros per patient because of travel cost and loss of income. The second alternative (direct fundus examination) required 2.69, 0.11, and 0.33 Euros per patient for personnel, consumables, and capital cost, respectively. All patients in this second alternative had to attend a consultation that implied travel and loss of income costs. Attending a consultation represented a cost of 48.29 Euros per patient. From the PHS perspective, direct fundus examination is less costly than using digital fundus images. The higher cost of the digital fundus option is a consequence of the higher capital costs required by the equipment needed to obtain the digital image. However, from a global perspective, the digital image alternative is more convenient because the travel cost and loss of income of the patient are lower.

  4. Use of digital ciné-fluoroscopy and catheter-directed techniques to improve and simplify standard vascular procedures.

    PubMed

    Wain, R A; Veith, F J

    1999-06-01

    Digital ciné-fluoroscopy and catheter-directed treatments have become indispensable tools in the armamentarium of surgeons performing vascular procedures. These new technologies not only improve and simplify the performance of standard vascular operations but also allow surgeons to perform a wide range of interventions previously unavailable in the operating room.

  5. A technique of direct tracing for recording digital range of motion.

    PubMed

    Macionis, Valdas

    2008-04-01

    This report describes a technique for recording range of motion of digital joints. The technique involves tracing digital outlines with an angled marker on a sheet of paper attached to a special interray pad. A complete dorsal silhouette of the entire ray can be obtained by mounting the pad and the paper astride the palm parallel to the ray of the digit being evaluated. Fabrication and use of the equipment is described. This silhouetting system could be an alternative to wire tracing in visualizing tendencies of dynamics of digital range of motion.

  6. Highly textured fresnoite thin films synthesized in situ by pulsed laser deposition with CO2 laser direct heating

    NASA Astrophysics Data System (ADS)

    Lorenz, Michael; de Pablos-Martin, Araceli; Patzig, Christian; Stölzel, Marko; Brachwitz, Kerstin; Hochmuth, Holger; Grundmann, Marius; Höche, Thomas

    2014-01-01

    Fresnoite Ba2TiSi2O8 (BTS) thin films were grown and crystallized in situ using pulsed laser deposition (PLD) with CO2 laser direct heating of the a-plane sapphire (1 1 0) substrates up to 1250 °C. Starting with 775 °C growth temperature, (0 0 1)- and (1 1 0)-textured BTS and BaTiO3 phases, respectively, could be assigned in the films, and the typical fern-like BTS crystallization patterns appear. For higher process temperatures of 1100 to 1250 °C, atomically smooth, terraced surface of the films was found, accompanied by crystalline high-temperature phases of Ba-Ti-Si oxides. HAADF micrographs taken in both scanning transmission electron microscopy and energy-dispersive x-ray spectrometry mode show details of morphology and elemental distribution inside the films and at the interface. To balance the inherent Si deficiency of the BTS films, growth from glassy BTS × 2 SiO2 and BTS × 2.5 SiO2 targets was considered as well. The latter targets are ideal for PLD since the employed glasses possess 100% of the theoretical density and are homogeneous at the atomic scale.

  7. Direct To Digital Holography For High Aspect Ratio Inspection of Semiconductor Wafers

    NASA Astrophysics Data System (ADS)

    Thomas, C. E. (Tommy); Hunt, Martin A.; Bahm, Tracy M.; Baylor, Larry R.; Bingham, Philip R.; Chidley, Matthew D.; Dai, Xiaolong; Delahanty, Robert J.; El-Khashab, Ayman; Gilbert, Judd M.; Goddard, James S.; Hanson, Gregory R.; Hickson, Joel D.; Hylton, Kathy W.; John, George C.; Jones, Michael L.; Mayo, Michael W.; Marek, Christopher; Price, John H.; Rasmussen, David A.; Schaefer, Louis J.; Schulze, Mark A.; Shen, Bichuan; Smith, Randall G.; Su, Allen N.; Tobin, Kenneth W.; Usry, William R.; Voelkl, Edgar; Weber, Karsten S.; Owen, Robert W.

    2003-09-01

    Direct to Digital Holography (DDH) has been developed as a semiconductor wafer inspection tool and in particular as a tool for seeing defects in high aspect ratio (HAR) structures on semiconductor wafers and also for seeing partial-height defects. While the tool works very well for general wafer inspection, it has unusual capabilities for high aspect ratio inspection (HARI) and for detecting thin residual film defects (partial height defects). Inspection of HAR structures is rated as one of the highest unmet priorities of the member companies of International SEMATECH, and finding residual thin film defects (in some cases called "stringers") is also a very difficult challenge. The capabilities that make DDH unusually sensitive include: 1) the capture of the whole wave—both the classical amplitude captured by traditional optical systems, and the phase of the wave, with phase potentially measured to ˜1/1000'th of a wavelength or ˜2 to 3 Angstroms for a deep ultra-violet (DUV) laser; 2) heterodyne detection—this allows it to capture very low signal levels; and 3) a head-on geometry using a collimated laser beam that allows best penetration of HAR structures. The basic features and methods of this patented technology are presented, along with simple calculations of signal strength and expected noise levels for various circumstances. Full-wave numerical calculations of electromagnetic field penetration into HAR contacts and experimental results from various wafer types and structures are also presented.

  8. Direct-to-digital holography reduction of reference hologram noise and fourier space smearing

    DOEpatents

    Voelkl, Edgar

    2006-06-27

    Systems and methods are described for reduction of reference hologram noise and reduction of Fourier space smearing, especially in the context of direct-to-digital holography (off-axis interferometry). A method of reducing reference hologram noise includes: recording a plurality of reference holograms; processing the plurality of reference holograms into a corresponding plurality of reference image waves; and transforming the corresponding plurality of reference image waves into a reduced noise reference image wave. A method of reducing smearing in Fourier space includes: recording a plurality of reference holograms; processing the plurality of reference holograms into a corresponding plurality of reference complex image waves; transforming the corresponding plurality of reference image waves into a reduced noise reference complex image wave; recording a hologram of an object; processing the hologram of the object into an object complex image wave; and dividing the complex image wave of the object by the reduced noise reference complex image wave to obtain a reduced smearing object complex image wave.

  9. Direct elicitation of template concentration from quantification cycle (Cq) distributions in digital PCR

    PubMed Central

    Mojtahedi, Mitra; Fouquier d'Hérouël, Aymeric; Huang, Sui

    2014-01-01

    Digital PCR (dPCR) exploits limiting dilution of a template into an array of PCR reactions. From this array the number of reactions that contain at least one (as opposed to zero) initial template is determined, allowing inferring the original template concentration. Here we present a novel protocol to efficiently infer the concentration of a sample and its optimal dilution for dPCR from few targeted qPCR assays. By taking advantage of the real-time amplification feature of qPCR as opposed to relying on endpoint PCR assessment as in standard dPCR prior knowledge of template concentration is not necessary. This eliminates the need for serial dilutions in a separate titration and reduces the number of necessary reactions. We describe the theory underlying our approach and discuss experimental moments that contribute to uncertainty. We present data from a controlled experiment where the initial template concentration is known as proof of principle and apply our method on directly monitoring transcript level change during cell differentiation as well as gauging amplicon numbers in cDNA samples after pre-amplification. PMID:25104023

  10. Doses under automatic exposure control (AEC) for direct digital radiographic (DDR) X-ray systems.

    PubMed

    Bowden, Louise; Faulkner, Ronan; Clancy, Conor; Gallagher, Aoife; Devine, Mark; Gorman, Dermot; O'Reilly, Geraldine; Dowling, Anita

    2011-09-01

    Current guidelines quote tolerances for automatic exposure control (AEC) device performance for X-ray systems as 'Baseline ± X %'. However, in the situation where a baseline figure has not yet been achieved, as in the case of commissioning assessments, this tolerance is not relevant. The purpose of this work is to provide mean doses for direct digital radiography (DDR) X-ray system, operating in AEC, against which comparisons can be made. Dose measurements have been recorded under AEC operation on 29 DDR detectors from three different manufacturers. Two different testing protocols were examined: (1) water equivalent phantoms in front of the DDR detector and (2) aluminium block at the tube head. The average patient exit dose, using the aluminium block was 4.6 μGy with the antiscatter grid in place and 4.0 μGy with the grid removed. Using the water phantoms, the average dose was measured at 17.1 μGy with the antiscatter grid in place and 5.4 μGy with grid removed. Based on these results, it is clear that different testing configurations significantly impact on the measured dose.

  11. DNA nanomechanics allows direct digital detection of complementary DNA and microRNA targets.

    PubMed

    Husale, Sudhir; Persson, Henrik H J; Sahin, Ozgur

    2009-12-24

    Techniques to detect and quantify DNA and RNA molecules in biological samples have had a central role in genomics research. Over the past decade, several techniques have been developed to improve detection performance and reduce the cost of genetic analysis. In particular, significant advances in label-free methods have been reported. Yet detection of DNA molecules at concentrations below the femtomolar level requires amplified detection schemes. Here we report a unique nanomechanical response of hybridized DNA and RNA molecules that serves as an intrinsic molecular label. Nanomechanical measurements on a microarray surface have sufficient background signal rejection to allow direct detection and counting of hybridized molecules. The digital response of the sensor provides a large dynamic range that is critical for gene expression profiling. We have measured differential expressions of microRNAs in tumour samples; such measurements have been shown to help discriminate between the tissue origins of metastatic tumours. Two hundred picograms of total RNA is found to be sufficient for this analysis. In addition, the limit of detection in pure samples is found to be one attomolar. These results suggest that nanomechanical read-out of microarrays promises attomolar-level sensitivity and large dynamic range for the analysis of gene expression, while eliminating biochemical manipulations, amplification and labelling.

  12. Index to ring digit ratio in Saudi Arabia at Almadinah Almonawarah province: a direct and indirect measurement study

    PubMed Central

    Almasry, Shaima M; El Domiaty, Magda A; Algaidi, Sami A; Elbastawisy, Yasser M; Safwat, Maha D

    2011-01-01

    The digit ratio, or the relative lengths, of the 2nd and 4th digits (2D : 4D) shows a sex difference, with males tending to have lower values in comparison with females. This sex differences arises early in the fetus and may result from the effects of prenatal testosterone and estrogen on the relative growth rate of the 2nd and 4th digits. This study aimed to estimate finger lengths and the 2D : 4D ratios for the first time in Saudi Arabian subjects using direct and indirect measurements, and to evaluate the correlations between both indirect and direct 2D : 4D with adult testosterone and various sexually dimorphic physical traits. The results revealed the following: (i) mean 2D : 4D in Saudi Arabian samples varied from 0.96 to 0.99; (ii) mean 2D : 4D was lower for indirect compared to direct 2D : 4D; (iii) sex differences in indirect 2D : 4D were higher than in direct 2D : 4D measurements; (iv) there were no significant correlations between indirect or direct 2D : 4D and testosterone level; (v) there were four significant correlations between direct 2D : 4D and body size traits but no significant correlations between indirect 2D : 4D and body size. PMID:21044064

  13. Syntheses of fully sulfonated polyaniline nano-networks and its application to the direct electrochemistry of cytochrome c.

    PubMed

    Zhang, Lei; Jiang, Xiue; Niu, Li; Dong, Shaojun

    2006-01-15

    Fully sulfonated polyaniline nano-particles, nano-fibrils and nano-networks have been achieved for the first time by electrochemical homopolymerization of orthanilic acid using a three-step electrochemical deposition procedure in a mixed solvent of acetonitrile (ACN) and water. The diameter of the uniform nano-particles is about 60 nm, and the nano-fibrils can be organized in two-dimensional (2D) or three-dimensional (3D) non-periodic networks with good electrical contact. Average distance between contacts is about 850 and 600nm for a 2D and 3D system, respectively. The details of the poly(orthanilic acid) (POA) nano-structure were examined with a field emission scanning electron microscope (SEM). The structure and properties of POA were characterized with FTIR, UV-vis and electrochemical methods. The 3D POA nano-networks coated platinum electrode gave a direct electrochemical behavior of horse heart cytochrome c (Cyt c) immobilized on this electrode surface, a pair of well-defined redox waves with formal potential (E( degrees ')) of -0.032 V (versus Ag/AgCl) was achieved. The interaction between Cyt c and POA makes the formal potential shift negatively compared to that of Cyt c in solution. Spectrophotometric and electrochemical methods were used to investigate the interaction of Cyt c with POA. The immobilized Cyt c in the nano-networks POA film maintained its activity, showing a surface-controlled electrode process with the electron transfer rate constant (k(s)) of 21s(-1) and a of 0.53, and could be used for the electrocatalytic reduction of hydrogen peroxide. The quantitative determination of Cyt c by differential pulse voltammetry (DPV) using the fully sulfonated 3D POA nano-networks film coated platinum electrode was also studied.

  14. An efficient assignment of drainage direction over flat surfaces in raster digital elevation models

    NASA Astrophysics Data System (ADS)

    Barnes, Richard; Lehman, Clarence; Mulla, David

    2014-01-01

    In processing raster digital elevation models (DEMs) it is often necessary to assign drainage directions over flats-that is, over regions with no local elevation gradient. This paper presents an approach to drainage direction assignment which is not restricted by a flat's shape, number of outlets, or surrounding topography. Flow is modeled by superimposing a gradient away from higher terrain with a gradient towards lower terrain resulting in a drainage field exhibiting flow convergence, an improvement over methods which produce regions of parallel flow. This approach builds on previous work by Garbrecht and Martz (1997), but presents several important improvements. The improved algorithm guarantees that flats are only resolved if they have outlets. The algorithm does not require iterative application; a single pass is sufficient to resolve all flats. The algorithm presents a clear strategy for identifying flats and their boundaries. The algorithm is not susceptible to loss of floating-point precision. Furthermore, the algorithm is efficient, operating in O(N) time whereas the older algorithm operates in O(N) time. In testing, the improved algorithm ran 6.5 times faster than the old for a 100×100 cell flat and 69 times faster for a 700×700 cell flat. In tests on actual DEMs, the improved algorithm finished its processing 38-110 times sooner while running on a single processor than a parallel implementation of the old algorithm did while running on 16 processors. The improved algorithm is an optimal, accurate, easy-to-implement drop-in replacement for the original. Pseudocode is provided in the paper and working source code is provided in the Supplemental Materials.

  15. Digital display holograms

    NASA Astrophysics Data System (ADS)

    Karnaukhov, V. N.; Merzlyakov, N. S.; Mozerov, M. G.; Dimitrov, L. I.; Wenger, E.

    1998-05-01

    Two digital display holograms (DDH) are synthesized to demonstrate the possibility of holographic display of 3D objects given by their mathematical descriptions only. 3D models of the objects and shaded 2D projections in varying viewing directions are generated using the methods of computer graphics. For each projection, a Fourier hologram was synthesized and encoded by the kinoform method. The recording of the obtained digital kinoforms on a commercially available photographic film was done by a computer-controlled laser device. This process produces, after film development and bleaching, a facet DDH. The complete DDHs have a size of 672×672 mm 2 and consist of 900 elementary holograms of 256×256 samples each, calculated for different directions within the solid angle of ±90°. They allow the visual representation of 3D objects with good quality.

  16. Digital mental health and intellectual disabilities: state of the evidence and future directions.

    PubMed

    Sheehan, Rory; Hassiotis, Angela

    2017-09-25

    The use of digital technologies in the management of mental illness, and more generally in the promotion of well-being and mental health, has received much recent attention and is a focus of current health policy. We conducted a narrative review to explore the opportunities and risks of digital technologies in mental healthcare specifically for people with intellectual disability, a sometimes marginalised and socially excluded group. The scope of digital mental health is vast and the promise of cheaper and more effective interventions delivered digitally is attractive. People with intellectual disability experience high rates of mental illness and could benefit from the development of novel therapies, yet seem to have been relatively neglected in the discourse around digital mental health and are often excluded from the development and implementation of new interventions. People with intellectual disability encounter several barriers to fully embracing digital technology, which may be overcome with appropriate support and adaptations. A small, but growing, literature attests to the value of incorporating digital technologies into the lives of people with intellectual disability, not only for promoting health but also for enhancing educational, vocational and leisure opportunities. Clearly further evidence is needed to establish the safety and clinical efficacy of digital mental health interventions for people with and without intellectual disability. A digital inclusion strategy that explicitly addresses the needs of people with intellectual disability would ensure that all can share the benefits of the digital world. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  17. Digital radiography system using a new direct-detection flat panel detector and its system performance

    NASA Astrophysics Data System (ADS)

    Park, Jong-Hwan; Kang, Won-Suk; Shin, Byung-Su; Kang, Hyun-Seung

    2009-02-01

    We developed a digital radiography (DR) system using a new amorphous selenium (a-Se) based direct-detection flatpanel detector which has a pixel pitch of 0.168mm, a fill factor of 83%, and a total active imaging area is 17"×17". Our new system consists of an X-ray generator, two flat-panel detectors, an X-ray tube, a bucky stand, a bucky table, a control box, an image processing unit and another component. The performance of this imaging system has been measured and compared with that of our previous system used an a-Se based flat-panel detector, however, which has a pixel pitch of 0.139mm, a fill factor of 82% and a total active imaging area of 14"×17". In order to evaluate the system performance quantitatively, the modulation transfer function (MTF), detective quantum efficiency (DQE) and noise power spectrum (NPS) were measured. At 3.0 lp./mm, the measured MTF was 56%, and DQE were 25% approximately for a new flat-panel detector. In case of the previously used flat-panel detector, the MTF and DQE at 3.0 lp./mm were 75% and 12%, respectively. The MTF of a new flat-panel detector was lower than that of a previous detector, however DQE of a new detector was higher than that of a previous detector at whole spatial frequency region. In conclusion, our new DR system is capable of providing good image quality in aspect of the physical characteristics although the MTF is relatively lower than previously developed system.

  18. Direct Digital Manufacturing of Integrated Naval Systems Using Ultrasonic Consolidation, Support Material Deposition and Direct Write Technologies

    DTIC Science & Technology

    2012-02-17

    with an integrated " tool changer " capable of interchangeably using a "direct write tool " for electronic material deposition, a "material extrusion head...Pump Fig. 26. The nScrypt direct write "Smart Pump" system (www.nscryptinc.com) Direct Write Deposition & CNC Milling Flexible FDM Machine Heated...oflntegrated Naval Systems Using Ultrasonic Consolidation, Support Material Deposition and Direct Write Technologies 5a. CONTRACT NUMBER N00014-07-1-0633

  19. Synthesizing speech

    NASA Astrophysics Data System (ADS)

    Siltanen, Samuli

    2015-01-01

    Samuli Siltanen explains how solving an "inverse problem" will improve the quality of life of people who can't speak and have to use voice synthesizers - particularly women and children, whose only current option is to sound like an adult male.

  20. Waveform synthesizer

    DOEpatents

    Franks, Larry A.; Nelson, Melvin A.

    1981-01-01

    A method of producing optical and electrical pulses of desired shape. An optical pulse of arbitrary but defined shape illuminates one end of an array of optical fiber waveguides of differing lengths to time differentiate the input pulse. The optical outputs at the other end of the array are combined to form a synthesized pulse of desired shape.

  1. Digital signal processing and control and estimation theory -- Points of tangency, area of intersection, and parallel directions

    NASA Technical Reports Server (NTRS)

    Willsky, A. S.

    1976-01-01

    A number of current research directions in the fields of digital signal processing and modern control and estimation theory were studied. Topics such as stability theory, linear prediction and parameter identification, system analysis and implementation, two-dimensional filtering, decentralized control and estimation, image processing, and nonlinear system theory were examined in order to uncover some of the basic similarities and differences in the goals, techniques, and philosophy of the two disciplines. An extensive bibliography is included.

  2. New directions in medical e-curricula and the use of digital repositories.

    PubMed

    Fleiszer, David M; Posel, Nancy H; Steacy, Sean P

    2004-03-01

    Medical educators involved in the growth of multimedia-enhanced e-curricula are increasingly aware of the need for digital repositories to catalogue, store and ensure access to learning objects that are integrated within their online material. The experience at the Faculty of Medicine at McGill University during initial development of a mainstream electronic curriculum reflects this growing recognition that repositories can facilitate the development of a more comprehensive as well as effective electronic curricula. Also, digital repositories can help to ensure efficient utilization of resources through the use, re-use, and reprocessing of multimedia learning, addressing the potential for collaboration among repositories and increasing available material exponentially. The authors review different approaches to the development of a digital repository application, as well as global and specific issues that should be examined in the initial requirements definition and development phase, to ensure current initiatives meet long-term requirements. Often, decisions regarding creation of e-curricula and associated digital repositories are left to interested faculty and their individual development teams. However, the development of an e-curricula and digital repository is not predominantly a technical exercise, but rather one that affects global pedagogical strategies and curricular content and involves a commitment of large-scale resources. Outcomes of these decisions can have long-term consequences and as such, should involve faculty at the highest levels including the dean.

  3. Synthesizing 2D and 3D Selenidostannates in Ionic Liquids: The Synergistic Structure-Directing Effects of Ionic Liquids and Metal-Amine Complexes.

    PubMed

    Du, Cheng-Feng; Shen, Nan-Nan; Li, Jian-Rong; Hao, Min-Ting; Wang, Zi; Huang, Xiao-Ying

    2016-05-20

    Presented are the ionothermal syntheses, characterizations, and properties of a series of two- and three-dimensional selenidostannate compounds synergistically directed by metal-amine complex (MAC) cations and ionic liquids (ILs) of [Bmmim]Cl (Bmmim=1-butyl-2,3-dimethylimidazolium). Four selenidostannates, namely, 2D-(Bmmim)3 [Ni(en)3 ]2 [Sn9 Se21 ]Cl (1, en=ethylenediamine), 2D-(Bmmim)8 [Ni2 (teta)2 (μ-teta)]Sn18 Se42 (2, teta=triethylenetetramine), 2D-(Bmmim)4 [Ni(tepa)Cl]2 [Ni(tepa)Sn12 Se28 ] (3, tepa=tetraethylenepentamine), and 3D-(Bmmim)2 [Ni(1,2-pda)3 ]Sn8 Se18 (4, 1,2-pda=1,2-diaminopropane), were obtained. Single-crystal X-ray diffraction analyses revealed that compounds 1 and 2 possess a lamellar anionic [Sn3 Se7 ]n (2n-) structure comprising distinct eight-membered ring units, whereas 3 features a MAC-decorated anionic [Ni(tepa)Sn12 Se28 ]n (6n-) layered structure. In contrast to 1-3, compound 4 exhibits a 3D open framework of anionic [Sn4 Se9 ]n (2n-) . The structural variation from 1 to 4 clearly indicates that on the basis of the synergistic structure-directing ability of the MACs and ILs, variation of the organic polyamine ligand has a significant impact on the formation of selenidostannates.

  4. Direct current pulse train actuation to enhance droplet control in digital microfluidics

    NASA Astrophysics Data System (ADS)

    Murran, Miguel A.; Najjaran, Homayoun

    2012-10-01

    The effective operation of a digital microfluidic (DMF) device depends on its ability to actuate droplets. Pulse width modulation of actuating signals (DC pulse train actuation) is proposed as a practical digital implementation and enhanced droplet manipulation technique. Experimental and simulation results demonstrate the efficacy of droplet incremental displacement and velocity control by modulating the width of each actuation pulse. This will in turn enable the control of the non-linear droplet transport dynamics to minimize droplet position overshoot, deformation, and fragmentation. As a result, DCPT actuation offers unparalleled control over droplet position and speed in DMF devices.

  5. Using Digital Technologies to Support Self-Directed Learning for Preservice Teacher Education

    ERIC Educational Resources Information Center

    Bullock, Shawn Michael

    2013-01-01

    This article begins with the perspective that teacher education programmes are cultural institutions and are thus compelled to respond to the societal push for teachers to be conversant in so-called twenty-first-century skills, grounded primarily in the ability to use digital technologies for pedagogical purposes. The results of an attempt to…

  6. Digital Learning Material for Student-Directed Model Building in Molecular Biology

    ERIC Educational Resources Information Center

    Aegerter-Wilmsen, Tinri; Coppens, Marjolijn; Janssen, Fred; Hartog, Rob; Bisseling, Ton

    2005-01-01

    The building of models to explain data and make predictions constitutes an important goal in molecular biology research. To give students the opportunity to practice such model building, two digital cases had previously been developed in which students are guided to build a model step by step. In this article, the development and initial…

  7. Using Digital Technologies to Support Self-Directed Learning for Preservice Teacher Education

    ERIC Educational Resources Information Center

    Bullock, Shawn Michael

    2013-01-01

    This article begins with the perspective that teacher education programmes are cultural institutions and are thus compelled to respond to the societal push for teachers to be conversant in so-called twenty-first-century skills, grounded primarily in the ability to use digital technologies for pedagogical purposes. The results of an attempt to…

  8. Digital Learning Material for Student-Directed Model Building in Molecular Biology

    ERIC Educational Resources Information Center

    Aegerter-Wilmsen, Tinri; Coppens, Marjolijn; Janssen, Fred; Hartog, Rob; Bisseling, Ton

    2005-01-01

    The building of models to explain data and make predictions constitutes an important goal in molecular biology research. To give students the opportunity to practice such model building, two digital cases had previously been developed in which students are guided to build a model step by step. In this article, the development and initial…

  9. Digital Game Violence and Direct Aggression in Adolescence: A Longitudinal Study of the Roles of Sex, Age, and Parent-Child Communication

    ERIC Educational Resources Information Center

    Wallenius, Marjut; Punamaki, Raija-Leena

    2008-01-01

    This study investigated the roles of sex, age, and parent-child communication in moderating the association between digital game violence and direct aggression in a two-year longitudinal study. Finnish 12- and 15-year-old adolescents (N = 316) participated in the follow-up survey. As hypothesized, digital game violence was linked to direct…

  10. Digital Game Violence and Direct Aggression in Adolescence: A Longitudinal Study of the Roles of Sex, Age, and Parent-Child Communication

    ERIC Educational Resources Information Center

    Wallenius, Marjut; Punamaki, Raija-Leena

    2008-01-01

    This study investigated the roles of sex, age, and parent-child communication in moderating the association between digital game violence and direct aggression in a two-year longitudinal study. Finnish 12- and 15-year-old adolescents (N = 316) participated in the follow-up survey. As hypothesized, digital game violence was linked to direct…

  11. Doses measured using AEC on direct digital radiographic (DDR) X-rays systems: updated results with an RP 162 perspective.

    PubMed

    Bowden, L; Faulkner, R; Gallagher, A; O'Connor, U; Walsh, C; Dowling, A; O'Reilly, G

    2013-02-01

    As digital technology in diagnostic radiology systems becomes more prevalent, there is a need to provide comparative dose information for these new systems. This is needed in particular for testing the automatic exposure control (AEC) devices on direct digital radiography (DDR) systems as there is no consensus on the receptor dose level in the current guidelines. The new European Commission RP 162 document sets the suspension level for the 'verification of kerma at receptor entrance in computed radiography and DDR systems under AEC' as ≥10 µGy. This document also notes that alternate methodologies are acceptable, and may require adjustment in the suspension level if used. This study provides a range of typical doses under AEC for DDR systems, for a variety measurement methodologies, including that described in RP 162.

  12. TiO2 film decorated with highly dispersed polyoxometalate nanoparticles synthesized by micelle directed method for the efficiency enhancement of dye-sensitized solar cells

    NASA Astrophysics Data System (ADS)

    He, Lifei; Chen, Li; Zhao, Yue; Chen, Weilin; Shan, Chunhui; Su, Zhongmin; Wang, Enbo

    2016-10-01

    In this work, two kinds of polyoxometalate (POM) nanoparticles with controlled shapes and structures were synthesized by micelle directed method and then composited with TiO2 via calcination to remove the surfactants owing to the excellent electronic storage and transmission ability of POM, finally obtaining two kinds of TiO2 composites with highly dispersed and small-sized POM nanoparticles (∼1 nm). The TiO2 composites were then induced into the photoanodes of dye-sensitized (N719) solar cells (DSSCs). The separation of electron-holes becomes more favorable due to the nanostructure and high dispersion of POM which provide more active sites than pure POM tending to agglomeration. The TiO2 composite photoanodes finally yielded the power conversion efficiency (PCE) of 8.4% and 8.2%, respectively, which were 42% and 39% higher than the pristine TiO2 based anodes. In addition, the mechanisms of POM in DSSC are proposed.

  13. Photothermal response of CVD synthesized carbon (nano)spheres/aqueous nanofluids for potential application in direct solar absorption collectors: a preliminary investigation

    PubMed Central

    Poinern, Gérrard Eddy Jai; Brundavanam, Sridevi; Shah, Monaliben; Laava, Iafeta; Fawcett, Derek

    2012-01-01

    Direct-absorption solar collectors have the potential to offer an unlimited source of renewable energy with minimal environmental impact. Unfortunately, their performance is limited by the absorption efficiency of the working fluid. Nanoparticles of functionalized carbon nanospheres (CNS) have the potential to improve the photothermal properties of the working fluid. CNS are produced by the pyrolysis of acetylene gas in a tube-based electric furnace/chemical vapor deposition apparatus. The reaction takes place at 1000°C in the presence of nitrogen gas without the use of a catalyst. The synthesized CNS were examined and characterized using field-emission scanning electron microscopy, transmission electron microscopy, X-ray diffraction spectroscopy, Raman spectroscopy, thermal gravimetric analysis, and ultraviolet-visible analysis. The CNS powders with a mean particle size of 210 nm were then functionalized using tetraethylammonium hydroxide ([C2H5]4 N[OH]) and used to produce a series of aqueous nanofluids with varying mass content. The photothermal response of both the nanofluids and films composed of CNS were investigated under 1000 W/m2 solar irradiation. PMID:24198496

  14. Photothermal response of CVD synthesized carbon (nano)spheres/aqueous nanofluids for potential application in direct solar absorption collectors: a preliminary investigation.

    PubMed

    Poinern, Gérrard Eddy Jai; Brundavanam, Sridevi; Shah, Monaliben; Laava, Iafeta; Fawcett, Derek

    2012-01-01

    Direct-absorption solar collectors have the potential to offer an unlimited source of renewable energy with minimal environmental impact. Unfortunately, their performance is limited by the absorption efficiency of the working fluid. Nanoparticles of functionalized carbon nanospheres (CNS) have the potential to improve the photothermal properties of the working fluid. CNS are produced by the pyrolysis of acetylene gas in a tube-based electric furnace/chemical vapor deposition apparatus. The reaction takes place at 1000°C in the presence of nitrogen gas without the use of a catalyst. The synthesized CNS were examined and characterized using field-emission scanning electron microscopy, transmission electron microscopy, X-ray diffraction spectroscopy, Raman spectroscopy, thermal gravimetric analysis, and ultraviolet-visible analysis. The CNS powders with a mean particle size of 210 nm were then functionalized using tetraethylammonium hydroxide ([C2H5]4 N[OH]) and used to produce a series of aqueous nanofluids with varying mass content. The photothermal response of both the nanofluids and films composed of CNS were investigated under 1000 W/m(2) solar irradiation.

  15. Field-emission property of self-purification SiC/SiOx coaxial nanowires synthesized via direct microwave irradiation using iron-containing catalyst

    NASA Astrophysics Data System (ADS)

    Zhou, Qing; Yu, Yongzhi; Huang, Shan; Meng, Jiang; Wang, Jigang

    2017-07-01

    SiC/SiOx coaxial nanowires were rapidly synthesized via direct microwave irradiation in low vacuum atmosphere. During the preparation process, only graphite, silicon, silicon dioxide powders were used as raw materials and iron-containing substance was employed as catalyst. Comprehensive characterizations were employed to investigate the microstructure of the products. The results showed that a great quantity of coaxial nanowires with uniform sizes and high aspect ratio had been successfully achieved. The coaxial nanowires consist of a silicon oxide (SiOx) shell and a β-phase silicon carbide (β-SiC) core that exhibited in special tube brush like. In additional, nearly all the products were achieved in the statement of pure SiC/SiOx coaxial nanowires without the existence of metallic catalyst, indicating that the self-removal of iron (Fe) catalyst should be occurred during the synthesis process. Photoluminescence (PL) spectral analysis result indicated that such novel SiC/SiOx coaxial nanowires exhibited significant blue-shift. Besides, the measurement results of field-emission (FE) demonstrated that the SiC/SiOx coaxial nanowires had ultralow turn-on field and threshold field with values of 0.2 and 2.1 V/μm, respectively. The hetero-junction structure formed between SiOx shell and SiC core, lots of emission sites, as well as clear tips of the nanowires were applied to explain the excellent FE properties.[Figure not available: see fulltext.

  16. Characterization of pore-expanded amino-functionalized mesoporous silicas directly synthesized with dimethyldecylamine and its application for decolorization of sulphonated azo dyes.

    PubMed

    Yang, Hong; Feng, Qiyan

    2010-08-15

    With dimethyldecylamine (DMDA) as the expander, a new kind of pore-expanded amino-functionalized mesoporous silicas (PEAFMS) was directly synthesized under mild alkali condition. The characteristics of PEAFMS sample demonstrated that the presence of DMDA markedly augmented the average pore diameter (19.04 nm) and strongly enhanced its decolorization ability. Subsequently, acid mordant dark yellow GG (YGG) and reactive red violet X-2R (RVX) were chosen to assess its adsorption capacity for sulphonated azo dyes. The effect of initial pH was investigated and the decolorization mechanism was illuminated. Three isotherms were conducted and the goodness of fit increased as the following order: Freundlich < Langmuir < Redlich-Peterson. The maximum adsorption capacities of YGG and RVX onto PEAFMS were 1.967 and 0.957 mmol/g, respectively. Adsorption kinetic processes were better predicted by the pseudo-second-order rate equation than the pseudo-first-order one. Adsorption thermodynamic results suggested that the adsorption behavior of both dyes onto PEAFMS was spontaneous with the chemical nature. In addition, the regeneration of PEAFMS was proved to be feasible using NaOH as the strippant. After five cycles, PEAFMS still possessed a favorable adsorption capacity for dyes. It is safely concluded that PEAFMS could be a potential adsorbent for the dye removal from wastewater. Copyright 2010 Elsevier B.V. All rights reserved.

  17. Synthesizing Chaos

    NASA Astrophysics Data System (ADS)

    Blakely, Jonathan; Corron, Ned; Hayes, Scott; Pethel, Shawn

    2007-03-01

    Chaos is usually attributed only to nonlinear systems. Yet it was recently shown that chaotic waveforms can be synthesized by linear superposition of randomly polarized basis functions. The basis function contains a growing oscillation that terminates in a large pulse. We show that this function is easily realized when viewed backward in time as a pulse followed by ringing decay. Consequently, a linear filter driven by random pulses outputs a waveform that, when viewed backward in time, exhibits essential qualities of chaos, i.e. determinism and a positive Lyapunov exponent. This phenomenon suggests that chaos may be connected to physical theories whose framework is not that of a deterministic dynamical system. We demonstrate that synthesizing chaos requires a balance between the topological entropy of the random source and the dissipation in the filter. Surprisingly, using different encodings of the random source, the same filter can produce both Lorenz-like and R"ossler-like waveforms. The different encodings can be viewed as grammar restrictions on a more general encoding that produces a chaotic superset encompassing the Lorenz and R"ossler paradigms of nonlinear dynamics. Thus, the language of deterministic chaos provides a useful description for a class of signals not generated by a deterministic system.

  18. Synthesizing Exoplanet Demographics: A Single Population of Long-period Planetary Companions to M Dwarfs Consistent with Microlensing, Radial Velocity, and Direct Imaging Surveys

    NASA Astrophysics Data System (ADS)

    Clanton, Christian; Gaudi, B. Scott

    2016-03-01

    We present the first study to synthesize results from five different exoplanet surveys using three independent detection methods: microlensing, radial velocity, and direct imaging. The constraints derived herein represent the most comprehensive picture of the demographics of large-separation (≳2 AU) planets orbiting the most common stars in our Galaxy that has been constructed to date. We assume a simple, joint power-law planet distribution function of the form {d}2{N}{{pl}}/(d{log} {m}p d{log} a)={ A }{({m}p/{M}{{Sat}})}α {(a/2.5{{AU}})}β with an outer cutoff radius of the separation distribution function of aout. Generating populations of planets from these models and mapping them into the relevant observables for each survey, we use actual or estimated detection sensitivities to determine the expected observations for each survey. Comparing with the reported results, we derive constraints on the parameters \\{α ,β ,{ A },{a}{{out}}\\} that describe a single population of planets that is simultaneously consistent with the results of microlensing, radial velocity, and direct imaging surveys. We find median and 68% confindence intervals of α =-{0.86}-0.19+0.21 (-{0.85}-0.19+0.21), β ={1.1}-1.4+1.9 ({1.1}-1.3+1.9), { A }={0.21}-0.15+0.20 {{dex}}-2 ({0.21}-0.15+0.20 {{dex}}-2), and {a}{{out}}={10}-4.7+26 AU ({12}-6.2+50 AU) assuming “hot-start” (“cold-start”) planet evolutionary models. These values are consistent with all current knowledge of planets on orbits beyond ∼2 AU around single M dwarfs.

  19. Effect of clock jitter on plasma density measurements relying on direct digital demodulation techniques

    NASA Astrophysics Data System (ADS)

    Hamming, B. W.; Colio, R. A.; Finkenthal, D. F.; van Zeeland, M. A.; Deterly, T. M.

    2011-10-01

    Real-time measurement of plasma density is essential to effective closed-loop plasma control systems in fusion-type reactors. The DIII-D tokamak currently employs a Michelson-type interferometer in combination with heterodyned lasers to make real-time density measurements utilizing embedded digital signal processing (DSP) techniques. This technique relies on high-speed analog-to-digital converters clocking at four times the 40 MHz reference frequency, and clock jitter becomes a critical source of noise in the measurement indistinguishable from phase noise of the interferometer signals. We present a study of the effect of clock jitter on system noise and recommendations for improvement. Work supported in part by US DOE under DE-FC02-04ER54698 and the National Undergraduate Fellowship in Fusion Science and Engineering.

  20. Digital learning material for student-directed model building in molecular biologyS.

    PubMed

    Aegerter-Wilmsen, Tinri; Coppens, Marjolijn; Janssen, Fred; Hartog, Rob; Bisseling, Ton

    2005-09-01

    The building of models to explain data and make predictions constitutes an important goal in molecular biology research. To give students the opportunity to practice such model building, two digital cases had previously been developed in which students are guided to build a model step by step. In this article, the development and initial evaluation of a third digital case is described. It concerns the selection of bristles during Drosophila development. To mimic a real research situation in a more realistic way, students are given much more freedom while building their models and can thus follow their own model-building approach. At the same time, however, students are provided with a sufficient amount of support to ensure that they can build their models without the requirement of intensive supervision.

  1. Direct-referencing Two-dimensional-array Digital Microfluidics Using Multi-layer Printed Circuit Board

    PubMed Central

    Gong, Jian; Kim, Chang-Jin “CJ”

    2008-01-01

    Digital (i.e. droplet-based) microfluidics, by the electrowetting-on-dielectric (EWOD) mechanism, has shown great potential for a wide range of applications, such as lab-on-a-chip. While most reported EWOD chips use a series of electrode pads essentially in one-dimensional line pattern designed for specific tasks, the desired universal chips allowing user-reconfigurable paths would require the electrode pads in two-dimensional pattern. However, to electrically access the electrode pads independently, conductive lines need to be fabricated underneath the pads in multiple layers, raising a cost issue especially for disposable chip applications. In this article, we report the building of digital microfluidic plates based on a printed-circuit-board (PCB), in which multilayer electrical access lines were created inexpensively using mature PCB technology. However, due to its surface topography and roughness and resulting high resistance against droplet movement, as-fabricated PCB surfaces require unacceptably high (~500 V) voltages unless coated with or immersed in oil. Our goal is EWOD operations of aqueous droplets not only on oil-covered but also on dry surfaces. To meet varying levels of performances, three types of gradually complex post-PCB microfabrication processes are developed and evaluated. By introducing land-grid-array (LGA) sockets in the packaging, a scalable digital microfluidics system with reconfigurable and low-cost chip is also demonstrated. PMID:19234613

  2. Direct Digital Demultiplexing of Analog TDM Signals for Cable Reduction in Ultrasound Imaging Catheters.

    PubMed

    Carpenter, Thomas M; Rashid, M Wasequr; Ghovanloo, Maysam; Cowell, David M J; Freear, Steven; Degertekin, F Levent

    2016-08-01

    In real-time catheter-based 3-D ultrasound imaging applications, gathering data from the transducer arrays is difficult, as there is a restriction on cable count due to the diameter of the catheter. Although area and power hungry multiplexing circuits integrated at the catheter tip are used in some applications, these are unsuitable for use in small sized catheters for applications, such as intracardiac imaging. Furthermore, the length requirement for catheters and limited power available to on-chip cable drivers leads to limited signal strength at the receiver end. In this paper, an alternative approach using analog time-division multiplexing (TDM) is presented, which addresses the cable restrictions of ultrasound catheters. A novel digital demultiplexing technique is also described, which allows for a reduction in the number of analog signal processing stages required. The TDM and digital demultiplexing schemes are demonstrated for an intracardiac imaging system that would operate in the 4- to 11-MHz range. A TDM integrated circuit (IC) with an 8:1 multiplexer is interfaced with a fast analog-to-digital converter (ADC) through a microcoaxial catheter cable bundle, and processed with a field-programmable gate array register-transfer level simulation. Input signals to the TDM IC are recovered with -40-dB crosstalk between the channels on the same microcoax, showing the feasibility of this system for ultrasound imaging applications.

  3. Method and apparatus for digitally based high speed x-ray spectrometer for direct coupled use with continuous discharge preamplifiers

    DOEpatents

    Warburton, W.K.

    1998-06-30

    A high speed, digitally based, signal processing system is disclosed which accepts directly coupled input data from a detector with a continuous discharge type preamplifier and produces a spectral analysis of the x-rays illuminating the detector. The system`s principal elements are an analog signal conditioning section, a combinatorial logic section which implements digital triangular filtering and pileup inspection, and a microprocessor which accepts values captured by the logic section and uses them to compute x-ray energy values. Operating without pole-zero correction, the system achieves high resolution by capturing, in conjunction with each peak value from the digital filter, an associated value of the unfiltered signal, and using this latter signal to correct the former for errors which arise from its local slope terms. This correction greatly reduces both energy resolution degradation and peak centroid shifting in the output spectrum as a function of input count rate. When the noise of this correction is excessive, a modification allows two filtered averages of the signal to be captured and a corrected peak amplitude computed therefrom. 14 figs.

  4. Method and apparatus for digitally based high speed x-ray spectrometer for direct coupled use with continuous discharge preamplifiers

    DOEpatents

    Warburton, William K.

    1998-01-01

    A high speed, digitally based, signal processing system which accepts directly coupled input data from a detector with a continuous discharge type preamplifier and produces a spectral analysis of the x-rays illuminating the detector. The system's principal elements are an analog signal conditioning section, a combinatorial logic section which implements digital triangular filtering and pileup inspection, and a microprocessor which accepts values captured by the logic section and uses them to compute x-ray energy values. Operating without pole-zero correction, the system achieves high resolution by capturing, in conjunction with each peak value from the digital filter, an associated value of the unfiltered signal, and using this latter signal to correct the former for errors which arise from its local slope terms. This correction greatly reduces both energy resolution degradation and peak centroid shifting in the output spectrum as a function of input count rate. When the noise of this correction is excessive, a modification allows two filtered averages of the signal to be captured and a corrected peak amplitude computed therefrom.

  5. Comparison of Accuracy of Conventional Periapical Radiography and Direct Digital Subtractions Radiography with or without Image Enhancement in the Diagnosis of Density Changes.

    PubMed

    Razi, Tahmineh; Mohammadi, Arezu; Ghojazadeh, Morteza

    2012-01-01

    In periapical radiographic technique, the changes will be visible only after considerable deposi-tion or resorption while digital subtraction technique visualizes slight density changes. This study was aimed to compare visualization of density changes in conventional periapical radiographs and digital subtraction technique with or without image enhancement. Three dry human mandibles with unspecified age and gender were selected. Conventional periapical and direct digital radiographs were taken from the anterior, and right and left posterior regions by step-wise placement of aluminum plates until the image of the plate was clearly visible. The radiographs taken with the direct digital technique were subtracted from the first radiograph using Photoshop software. Three observers evaluated the radiographs and the digital subtraction images with or without image enhancement. The density was recorded in each radiograph in which the image of the aluminum plate was completely visible. In all mandibles, the differences in diagnosis of densitychanges between the conventional periapical radiographic technique and the direct digital subtraction radiographic technique with or without image enhancement were statistically significant irrespective of the region under study (p<0.001). There were no significant differences in the diagnosis of density changes in all the three mandibles in the left and right posterior regions between the two radiographic techniques. However, the differences in the anterior region were statistically significant (p<0.001). Direct digital subtraction radiographic technique with or without image enhancement is a more efficacious technique in exhibiting minor density changes compared to conventional periapical radiographic technique.

  6. Digital first order hold circuit

    NASA Technical Reports Server (NTRS)

    Chan, Fred N. (Inventor); Wensley, Gerald J. (Inventor)

    1989-01-01

    There is provided a digitally controlled first order hold circuit and waveform synthesizer for digitally controlling the representation of a function over an approximation interval. In accordance with the operation of the invention, the first order hold circuit and waveform generator receives a digital data input signal which contains initial condition data, up/down data, and slope data for the approximation interval. The initial condition data is loaded into an up/down counter which is incremented using counting data at a rate depending on the value of the slope data and in a direction depending on the value of the up-down data. In order to minimize delays arising from data acquistion, two frequency synthesizer circuits are provided such that one frequency synthesizer provides counting data while the other frequency synthesizer receives slope data. During alternating intervals, the other frequency synthesizer circuit provides counting data while the other circuit receives slope data. In addition, long length data input signals covering a plurality of approximation intervals are provided to reduce the demands on a main system central processing unit.

  7. Direct Digital Demultiplexing of Analog TDM Signals for Cable Reduction in Ultrasound Imaging Catheters

    PubMed Central

    Carpenter, Thomas M.; Rashid, M. Wasequr; Ghovanloo, Maysam; Cowell, David M. J.; Freear, Steven; Degertekin, F. Levent

    2016-01-01

    In real-time catheter based 3D ultrasound imaging applications, gathering data from the transducer arrays is difficult as there is a restriction on cable count due to the diameter of the catheter. Although area and power hungry multiplexing circuits integrated at the catheter tip are used in some applications, these are unsuitable for use in small sized catheters for applications like intracardiac imaging. Furthermore, the length requirement for catheters and limited power available to on-chip cable drivers leads to limited signal strength at the receiver end. In this paper an alternative approach using Analog Time Division Multiplexing (TDM) is presented which addresses the cable restrictions of ultrasound catheters. A novel digital demultiplexing technique is also described which allows for a reduction in the number of analog signal processing stages required. The TDM and digital demultiplexing schemes are demonstrated for an intracardiac imaging system that would operate in the 4 MHz to 11 MHz range. A TDM integrated circuit (IC) with 8:1 multiplexer is interfaced with a fast ADC through a micro-coaxial catheter cable bundle, and processed with an FPGA RTL simulation. Input signals to the TDM IC are recovered with −40 dB crosstalk between channels on the same micro-coax, showing the feasibility of this system for ultrasound imaging applications. PMID:27116738

  8. Digital signal processor-based high-precision on-line Voigt lineshape fitting for direct absorption spectroscopy.

    PubMed

    Xu, Lijun; Liu, Chang; Zheng, Deyan; Cao, Zhang; Cai, Weiwei

    2014-12-01

    To realize on-line high-accuracy measurement in direct absorption spectroscopy (DAS), a system-on-chip, high-precision digital signal processor-based on-line Voigt lineshape fitting implementation is introduced in this paper. Given that the Voigt lineshape is determined by the Gauss full width at half maximum (FWHM) and Lorentz FWHM, a look-up table, which covers a range of combinations of both, is first built to achieve rapid and accurate calculation of Voigt lineshape. With the look-up table and raw absorbance data in hand, Gauss-Newton nonlinear fitting module is implemented to obtain the parameters including both the Gauss and Lorentz FWHMs, which can be used to calculate the integrated absorbance. To realize the proposed method in hardware, a digital signal processor (DSP) is adopted to fit the Voigt lineshape in a real-time DAS measurement system. In experiment, temperature and H2O concentration of a flat flame are recovered from the transitions of 7444.36 cm(-1) and 7185.6 cm(-1) by the DSP-based on-line Voigt lineshape fitting and on-line integral of the raw absorbance, respectively. The results show that the proposed method can not only fit the Voigt lineshape on-line but also improve the measurement accuracy compared with those obtained from the direct integral of the raw absorbance.

  9. A direct droplet digital PCR method for quantification of residual DNA in protein drugs produced in yeast cells.

    PubMed

    Hussain, Musaddeq; Fantuzzo, Rebecca; Mercorelli, Suzanne; Cullen, Constance

    2016-05-10

    Yeast cells, in particular Pichia pastoris, are the host cell of choice for manufacturing several protein therapeutic agents in the biopharmaceutical industry. Host cell DNA is an impurity of such manufacturing process and the residual DNA after the purification process of the drug must be monitored to ensure drug purity and safety. Currently, real-time PCR (qPCR) based methods are widely employed for quantification of host residual DNA. At the same time the digital PCR technology is coming into prominence with promise of higher sensitivity. Here we report a method where the protein drug is directly added to the droplet digital PCR (ddPCR) reaction including yeast-specific primers and fluorescent-tagged probe and nanoliter-sized droplets are generated. The droplets are then subjected to PCR followed by analysis for fluorescence. This Pichia residual DNA direct ddPCR method for yeast can be used to test higher amount of drug compared to the corresponding qPCR method thereby increasing sensitivity, retaining high precision and accuracy and has a wide linear range of determination. The method has been successfully tested with three batches of a recombinant human IgG1-Fc-based drug (RP-1) and with commercially available human insulin, both manufactured in yeast cells. This method simplifies the residual DNA quantification protocol by eliminating DNA extraction or protease digestion and eliminates use of DNA standards in day-to-day running of the method.

  10. Digital 2D-photogrammetry and direct anthropometry--a comparing study on test accomplishment and measurement data.

    PubMed

    Franke-Gromberg, Christine; Schüler, Grit; Hermanussen, Michael; Scheffler, Christiane

    2010-01-01

    The aim of this methodological anthropometric study was to compare direct anthropometry and digital two-dimensional photogrammetry in 18 male and 27 female subjects, aged 24 to 65 years, from Potsdam, Germany. In view of the rising interest in reliable biometric kephalofacial data, we focussed on head and face measurements. Out of 34 classic facial anatomical landmarks, 27 landmarks were investigated both by direct anthropometry and 2D-photogrammetry; 7 landmarks could not be localized by 2D-photogrammetry. Twenty-six kephalofacial distances were analysed both by direct anthropometry and digital 2D-photogrammetry. Kephalofacial distances are on average 7.6% shorter when obtained by direct anthropometry. The difference between the two techniques is particularly evident in total head height (vertex-gnathion) due to the fact that vertex is usually covered by hair and escapes from photogrammetry. Also the distances photographic sellion-gnathion (1.3 cm, i. e. 11.6%) and nasal-gnathion (1.2 cm, i. e. 9.4%) differ by more than one centimetre. Differences below 0.5 cm between the two techniques were found when measuring mucosa-lip-height (2.2%), gonia (3.0%), glabella-stomion (3.9%), and nose height (glabella-subnasal) (4.0%). Only the estimates of forehead width were significantly narrower when obtained by 2D-photogrammetry (-1.4 cm, -13.1%). The methodological differences increased with increasing magnitude of the kephalometric distance. Apart from these limitations, both techniques are similarly valid and may replace each other.

  11. Reconfigurable multivariable control law for commercial airplane using a direct digital output feedback design

    NASA Technical Reports Server (NTRS)

    Ostroff, A. J.; Hueschen, R. M.

    1984-01-01

    The ability of a pilot to reconfigure the control surfaces on an airplane after a failure, allowing the airplane to recover to a safe condition for landing, becomes more difficult with increasing airplane complexity. Techniques are needed to stabilize and control the airplane immediately after a failure, allowing the pilot time to make longer range decisions. This paper shows a design of a discrete multivariable control law using four controls for the longitudinal channel of a B-737. Single control element failures are allowed in three of the four controls. The four controls design and failure cases are analyzed by means of a digital airplane simulation, with regard to tracking capability and ability to overcome severe windshear and turbulence during the aproach and landing phase of flight.

  12. Flash Dent: an alternative charge-coupled device/scintillator-based direct digital intraoral radiographic system.

    PubMed

    Scarfe, W C; Farman, A G; Kelly, M S

    1994-02-01

    The Flash Dent digital intraoral radiographic system is yet to be described in the scientific literature. A Windows operating environment, a lens based optical scintillator charge-coupled device (CCD) and 'IMG' image format are the major features which distinguish this from other available systems. In this paper we describe the component of the Flash Dent system, investigate the validity of the X-ray generator specifications, determine comparative image doses and assess the performance of the intraoral sensor. Although we found Flash Dent software facilitates image processing, X-ray generator operation, sensor performance and dimensional measurements, inconsistencies between sensors and the use of a non-standard image format require further consideration for improvements on the part of the manufacturer.

  13. A defocus-information-free autostereoscopic three-dimensional (3D) digital reconstruction method using direct extraction of disparity information (DEDI)

    NASA Astrophysics Data System (ADS)

    Li, Da; Cheung, Chifai; Zhao, Xing; Ren, Mingjun; Zhang, Juan; Zhou, Liqiu

    2016-10-01

    Autostereoscopy based three-dimensional (3D) digital reconstruction has been widely applied in the field of medical science, entertainment, design, industrial manufacture, precision measurement and many other areas. The 3D digital model of the target can be reconstructed based on the series of two-dimensional (2D) information acquired by the autostereoscopic system, which consists multiple lens and can provide information of the target from multiple angles. This paper presents a generalized and precise autostereoscopic three-dimensional (3D) digital reconstruction method based on Direct Extraction of Disparity Information (DEDI) which can be used to any transform autostereoscopic systems and provides accurate 3D reconstruction results through error elimination process based on statistical analysis. The feasibility of DEDI method has been successfully verified through a series of optical 3D digital reconstruction experiments on different autostereoscopic systems which is highly efficient to perform the direct full 3D digital model construction based on tomography-like operation upon every depth plane with the exclusion of the defocused information. With the absolute focused information processed by DEDI method, the 3D digital model of the target can be directly and precisely formed along the axial direction with the depth information.

  14. Independent digit movements and precision grip patterns in 1-5-month-old human infants: hand-babbling, including vacuous then self-directed hand and digit movements, precedes targeted reaching.

    PubMed

    Wallace, Patricia S; Whishaw, Ian Q

    2003-01-01

    Previous work has described human reflexive grasp patterns in early infancy and visually guided reaching and grasping in late infancy. There has been no examination of hand movements in the intervening period. This was the purpose of the present study. We video recorded the spontaneous hand and digit movements made by alert infants over their first 5 months of age. Over this period, spontaneous hand and digit movements developed from fists to almost continuous, vacuous movements and then to self-directed grasping movements. Amongst the many hand and digit movements observed, four grasping patterns emerged during this period: fists, pre-precision grips associated with numerous digit postures, precision grips including the pincer grasp, and self-directed grasps. The finding that a wide range of independent digit movements and grasp patterns are displayed spontaneously by infants within their first 5 months of age is discussed in relation to the development of the motor system, including the suggestion that direct connections of the pyramidal tract are functional relatively early in infancy. It is also suggested that hand babbling, consisting of first vacuous and then self-directed movements, is preparatory to targeted reaching.

  15. Method to suppress DDFS spurious signals in a frequency-hopping synthesizer with DDFS-driven PLL architecture.

    PubMed

    Kwon, Kun-Sup; Yoon, Won-Sang

    2010-01-01

    In this paper we propose a method of removing from synthesizer output spurious signals due to quasi-amplitude modulation and superposition effect in a frequency-hopping synthesizer with direct digital frequency synthesizer (DDFS)-driven phase-locked loop (PLL) architecture, which has the advantages of high frequency resolution, fast transition time, and small size. There are spurious signals that depend on normalized frequency of DDFS. They can be dominant if they occur within the PLL loop bandwidth. We suggest that such signals can be eliminated by purposefully creating frequency errors in the developed synthesizer.

  16. Digital Game Playing and Direct and Indirect Aggression in Early Adolescence: The Roles of Age, Social Intelligence, and Parent-Child Communication.

    PubMed

    Wallenius, Marjut; Punamäki, Raija-Leena; Rimpelä, Arja

    2007-04-01

    The roles of age, social intelligence and parent-child communication in moderating the association between digital game playing and direct and indirect aggression were examined in 478 Finnish 10- and 13-year-old schoolchildren based on self-reports. The results confirmed that digital game violence was directly associated with direct aggression, especially at age 10, but only among boys. The moderating role of social intelligence was substantiated among older boys: game violence was associated with indirect aggression among those with high level of social intelligence. Further, as hypothesized, digital game playing was associated with direct aggression especially when parent-child communication was poor, but only among boys. Our findings emphasize the importance of individual and situational factors as moderators of the link between game violence and aggression.

  17. Evaluation of JPEG and wavelet compression of body CT images for direct digital teleradiologic transmission.

    PubMed

    Kalyanpur, A; Neklesa, V P; Taylor, C R; Daftary, A R; Brink, J A

    2000-12-01

    To determine acceptable levels of JPEG (Joint Photographic Experts Group) and wavelet compression for teleradiologic transmission of body computed tomographic (CT) images. A digital test pattern (Society of Motion Picture and Television Engineers, 512 x 512 matrix) was transmitted after JPEG or wavelet compression by using point-to-point and Web-based teleradiology, respectively. Lossless, 10:1 lossy, and 20:1 lossy ratios were tested. Images were evaluated for high- and low-contrast resolution, sensitivity to small signal differences, and misregistration artifacts. Three independent observers who were blinded to the compression scheme evaluated these image quality measures in 20 clinical cases with similar levels of compression. High-contrast resolution was not diminished with any tested level of JPEG or wavelet compression. With JPEG compression, low-contrast resolution was not lost with 10:1 lossy compression but was lost at 3% modulation with 20:1 lossy compression. With wavelet compression, there was loss of 1% modulation with 10:1 lossy compression and loss of 5% modulation with 20:1 lossy compression. Sensitivity to small signal differences (5% and 95% of the maximal signal) diminished only with 20:1 lossy wavelet compression. With 10:1 lossy compression, misregistration artifacts were mild and were equivalent with JPEG and wavelet compression. Qualitative clinical findings supported these findings. Lossy 10:1 compression is suitable for on-call electronic transmission of body CT images as long as original images are subsequently reviewed.

  18. Rewritable digital data storage in live cells via engineered control of recombination directionality

    PubMed Central

    Bonnet, Jerome; Subsoontorn, Pakpoom; Endy, Drew

    2012-01-01

    The use of synthetic biological systems in research, healthcare, and manufacturing often requires autonomous history-dependent behavior and therefore some form of engineered biological memory. For example, the study or reprogramming of aging, cancer, or development would benefit from genetically encoded counters capable of recording up to several hundred cell division or differentiation events. Although genetic material itself provides a natural data storage medium, tools that allow researchers to reliably and reversibly write information to DNA in vivo are lacking. Here, we demonstrate a rewriteable recombinase addressable data (RAD) module that reliably stores digital information within a chromosome. RAD modules use serine integrase and excisionase functions adapted from bacteriophage to invert and restore specific DNA sequences. Our core RAD memory element is capable of passive information storage in the absence of heterologous gene expression for over 100 cell divisions and can be switched repeatedly without performance degradation, as is required to support combinatorial data storage. We also demonstrate how programmed stochasticity in RAD system performance arising from bidirectional recombination can be achieved and tuned by varying the synthesis and degradation rates of recombinase proteins. The serine recombinase functions used here do not require cell-specific cofactors and should be useful in extending computing and control methods to the study and engineering of many biological systems. PMID:22615351

  19. Frequency domain near-infrared multiwavelength imager design using high-speed, direct analog-to-digital conversion

    PubMed Central

    Zimmermann, Bernhard B.; Fang, Qianqian; Boas, David A.; Carp, Stefan A.

    2016-01-01

    Abstract. Frequency domain near-infrared spectroscopy (FD-NIRS) has proven to be a reliable method for quantification of tissue absolute optical properties. We present a full-sampling direct analog-to-digital conversion FD-NIR imager. While we developed this instrument with a focus on high-speed optical breast tomographic imaging, the proposed design is suitable for a wide-range of biophotonic applications where fast, accurate quantification of absolute optical properties is needed. Simultaneous dual wavelength operation at 685 and 830 nm is achieved by concurrent 67.5 and 75 MHz frequency modulation of each laser source, respectively, followed by digitization using a high-speed (180  MS/s) 16-bit A/D converter and hybrid FPGA-assisted demodulation. The instrument supports 25 source locations and features 20 concurrently operating detectors. The noise floor of the instrument was measured at <1.4  pW/√Hz, and a dynamic range of 115+ dB, corresponding to nearly six orders of magnitude, has been demonstrated. Titration experiments consisting of 200 different absorption and scattering values were conducted to demonstrate accurate optical property quantification over the entire range of physiologically expected values. PMID:26813081

  20. Frequency domain near-infrared multiwavelength imager design using high-speed, direct analog-to-digital conversion

    NASA Astrophysics Data System (ADS)

    Zimmermann, Bernhard B.; Fang, Qianqian; Boas, David A.; Carp, Stefan A.

    2016-01-01

    Frequency domain near-infrared spectroscopy (FD-NIRS) has proven to be a reliable method for quantification of tissue absolute optical properties. We present a full-sampling direct analog-to-digital conversion FD-NIR imager. While we developed this instrument with a focus on high-speed optical breast tomographic imaging, the proposed design is suitable for a wide-range of biophotonic applications where fast, accurate quantification of absolute optical properties is needed. Simultaneous dual wavelength operation at 685 and 830 nm is achieved by concurrent 67.5 and 75 MHz frequency modulation of each laser source, respectively, followed by digitization using a high-speed (180 MS/s) 16-bit A/D converter and hybrid FPGA-assisted demodulation. The instrument supports 25 source locations and features 20 concurrently operating detectors. The noise floor of the instrument was measured at <1.4 pW/√Hz, and a dynamic range of 115+ dB, corresponding to nearly six orders of magnitude, has been demonstrated. Titration experiments consisting of 200 different absorption and scattering values were conducted to demonstrate accurate optical property quantification over the entire range of physiologically expected values.

  1. An Evidence-Based Systematic Review of Directional Microphones and Digital Noise Reduction Hearing Aids in School-Age Children With Hearing Loss

    PubMed Central

    McCreery, Ryan W.; Venediktov, Rebecca A.; Coleman, Jaumeiko J.; Leech, Hillary M.

    2013-01-01

    Purpose The purpose of this evidence-based systematic review was to evaluate the efficacy of digital noise reduction and directional microphones for outcome measures of audibility, speech recognition, speech and language, and self- or parent-report in pediatric hearing aid users. Method The authors searched 26 databases for experimental studies published after 1980 addressing one or more clinical questions and meeting all inclusion criteria. The authors evaluated studies for methodological quality and reported or calculated p values and effect sizes when possible. Results A systematic search of the literature resulted in the inclusion of 4 digital noise reduction and 7 directional microphone studies (in 9 journal articles) that addressed speech recognition, speech and language, and/or self-or parent-report outcomes. No digital noise reduction or directional microphone studies addressed audibility outcomes. Conclusions On the basis of a moderate level of evidence, digital noise reduction was not found to improve or degrade speech understanding. Additional research is needed before conclusions can be drawn regarding the impact of digital noise reduction on important speech, language, hearing, and satisfaction outcomes. Moderate evidence also indicates that directional microphones resulted in improved speech recognition in controlled optimal settings; however, additional research is needed to determine the effectiveness of directional microphones in actual everyday listening environments. PMID:22858614

  2. An evidence-based systematic review of directional microphones and digital noise reduction hearing aids in school-age children with hearing loss.

    PubMed

    McCreery, Ryan W; Venediktov, Rebecca A; Coleman, Jaumeiko J; Leech, Hillary M

    2012-12-01

    The purpose of this evidence-based systematic review was to evaluate the efficacy of digital noise reduction and directional microphones for outcome measures of audibility, speech recognition, speech and language, and self- or parent-report in pediatric hearing aid users. The authors searched 26 databases for experimental studies published after 1980 addressing one or more clinical questions and meeting all inclusion criteria. The authors evaluated studies for methodological quality and reported or calculated p values and effect sizes when possible. A systematic search of the literature resulted in the inclusion of 4 digital noise reduction and 7 directional microphone studies (in 9 journal articles) that addressed speech recognition, speech and language, and/or self- or parent-report outcomes. No digital noise reduction or directional microphone studies addressed audibility outcomes. On the basis of a moderate level of evidence, digital noise reduction was not found to improve or degrade speech understanding. Additional research is needed before conclusions can be drawn regarding the impact of digital noise reduction on important speech, language, hearing, and satisfaction outcomes. Moderate evidence also indicates that directional microphones resulted in improved speech recognition in controlled optimal settings; however, additional research is needed to determine the effectiveness of directional microphones in actual everyday listening environments.

  3. Direct-write fabrication of a nanoscale digital logic element on a single nanowire

    NASA Astrophysics Data System (ADS)

    Roy, Somenath; Gao, Zhiqiang

    2010-06-01

    In this paper we report on the 'direct-write' fabrication and electrical characteristics of a nanoscale logic inverter, integrating enhancement-mode (E-mode) and depletion-mode (D-mode) field-effect transistors (FETs) on a single zinc oxide (ZnO) nanowire. 'Direct-writing' of platinum metal electrodes and a dielectric layer is executed on individual single-crystalline ZnO nanowires using either a focused electron beam (FEB) or a focused ion beam (FIB). We fabricate a top-gate FET structure, in which the gate electrode wraps around the ZnO nanowire, resulting in a more efficient gate response than the conventional back-gate nanowire transistors. For E-mode device operation, the gate electrode (platinum) is deposited directly onto the ZnO nanowire by a FEB, which creates a Schottky barrier and in turn a fully depleted channel. Conversely, sandwiching an insulating layer between the FIB-deposited gate electrode and the nanowire channel makes D-mode operation possible. Integrated E- and D-mode FETs on a single nanowire exhibit the characteristics of a direct-coupled FET logic (DCFL) inverter with a high gain and noise margin.

  4. A radio-frequency source using direct digital synthesis and field programmable gate array for nuclear magnetic resonance.

    PubMed

    Liang, Xiao; Weimin, Wang

    2009-12-01

    A radio-frequency (rf) source for nuclear magnetic resonance (NMR) is described. With the application of direct digital synthesis (DDS), the rf source has the ability to yield rf pulses with short switching time and high resolution in frequency and phase. To facilitate the generation of a soft pulse, a field programmable gate array (FPGA) cooperating with a pulse programmer is used as the auxiliary controller of the DDS chip. Triggered by the pulse programmer, the FPGA automatically controls the DDS to generate soft pulse according to predefined parameters, and the operation mode of the pulse programmer is optimized. The rf source is suitable for being used as transmitter in low-field (<1 T) NMR applications, for example, magnetic resonance imaging and relaxation measurement. As a compact and low-cost module, the rf source is of general use for constructing low-field NMR spectrometer.

  5. Study on Construction of a Medical X-Ray Direct Digital Radiography System and Hybrid Preprocessing Methods

    PubMed Central

    Ren, Yong; Wu, Sheng; Wang, Mijian; Cen, Zhongjie

    2014-01-01

    We construct a medical X-ray direct digital radiography (DDR) system based on a CCD (charge-coupled devices) camera. For the original images captured from X-ray exposure, computer first executes image flat-field correction and image gamma correction, and then carries out image contrast enhancement. A hybrid image contrast enhancement algorithm which is based on sharp frequency localization-contourlet transform (SFL-CT) and contrast limited adaptive histogram equalization (CLAHE), is proposed and verified by the clinical DDR images. Experimental results show that, for the medical X-ray DDR images, the proposed comprehensive preprocessing algorithm can not only greatly enhance the contrast and detail information, but also improve the resolution capability of DDR system. PMID:25013452

  6. Direct determination of the ultimate performance of the RSFQ digital devices and single flux quantum voltage amplifiers

    NASA Astrophysics Data System (ADS)

    Goldobin, E. B.; Golomidov, V. M.; Kaplunenko, V. K.; Khabipov, M. I.; Khokhlov, D. Yu.; Kidiyarova-Shevchenko, A. Yu.

    1993-03-01

    The fault-free switching of single-flux-quantum (SFQ) elements was studied by investigating SFQ pulse propagation in a ring Josephson transmission line closed with an SFQ inverter. A lifetime of more than a few hours was obtained that corresponds to at least 10 exp 15 fault-free switching. The completely dc-powered rapid SFQ (RSFQ) sampler was used to directly measure the repetition rate stability of a Josephson generator loaded by a uniformly shunted transmission line. A stable repetition rate up to 7 GHz was obtained. The authors also report experimental results for two-stage serial and five-stage parallel quasi-digital amplifiers. The precision calculation of the input SFQ pulses is the main idea of these circuits.

  7. Digital metamaterials.

    PubMed

    Della Giovampaola, Cristian; Engheta, Nader

    2014-12-01

    Balancing complexity and simplicity has played an important role in the development of many fields in science and engineering. One of the well-known and powerful examples of such balance can be found in Boolean algebra and its impact on the birth of digital electronics and the digital information age. The simplicity of using only two numbers, '0' and '1', in a binary system for describing an arbitrary quantity made the fields of digital electronics and digital signal processing powerful and ubiquitous. Here, inspired by the binary concept, we propose to develop the notion of digital metamaterials. Specifically, we investigate how one can synthesize an electromagnetic metamaterial with a desired permittivity, using as building blocks only two elemental materials, which we call 'metamaterial bits', with two distinct permittivity functions. We demonstrate, analytically and numerically, how proper spatial mixtures of such metamaterial bits lead to elemental 'metamaterial bytes' with effective material parameters that are different from the parameters of the metamaterial bits. We then apply this methodology to several design examples of optical elements, such as digital convex lenses, flat graded-index digital lenses, digital constructs for epsilon-near-zero (ENZ) supercoupling and digital hyperlenses, thus highlighting the power and simplicity of the methodology.

  8. Latent feature representation with depth directional long-term recurrent learning for breast masses in digital breast tomosynthesis

    NASA Astrophysics Data System (ADS)

    Kim, Dae Hoe; Kim, Seong Tae; Chang, Jung Min; Ro, Yong Man

    2017-02-01

    Characterization of masses in computer-aided detection systems for digital breast tomosynthesis (DBT) is an important step to reduce false positive (FP) rates. To effectively differentiate masses from FPs in DBT, discriminative mass feature representation is required. In this paper, we propose a new latent feature representation boosted by depth directional long-term recurrent learning for characterizing malignant masses. The proposed network is designed to encode mass characteristics in two parts. First, 2D spatial image characteristics of DBT slices are encoded as a slice feature representation by convolutional neural network (CNN). Then, depth directional characteristics of masses among the slice feature representations are encoded by the proposed depth directional long-term recurrent learning. In addition, to further improve the class discriminability of latent feature representation, we have devised three objective functions aiming to (a) minimize classification error, (b) minimize intra-class variation within the same class, and (c) preserve feature representation consistency in a central slice. Experimental results have demonstrated that the proposed latent feature representation achieves a higher level of classification performance in terms of receiver operating characteristic (ROC) curves and the area under the ROC curve values compared to performance with feature representation learned by conventional CNN and hand-crafted features.

  9. Comparison of radiovisiography and digital volume tomography to direct surgical measurements in the detection of infrabony defects

    PubMed Central

    Raichur, Preeti S.; Setty, Swati B.; Thakur, Srinath L.

    2012-01-01

    Objectives: To compare the linear measurements of Radiovisiography (RVG) and Digital volume tomography (DVT) to direct surgical measurements in the detection of periodontal infrabony defects. Study Design: RVG and DVT images were taken prior to periodontal surgery for 28 infrabony periodontal defects. After defect debridement, direct bony defect measurements were made from the cemento enamel junction (CEJ) to the base of the defect (CEJ-BD) and to the alveolar crest (CEJ-AC) with a periodontal probe. These same measurements were made on the RVG and DVT images and then compared to the direct surgical values. Results: DVT correlated strongly with surgical measurements, whereas RVG correlated less favorably (P=0.0109, P=0.0193 respectively).No significant difference for CEJ-AC (P=0.0599) was seen between DVT and surgical measurements; however, there was a significant difference for the distance CEJ-BD (P=0.0105). Conclusion: DVT technique is significantly more accurate than RVG in the detection of infrabony periodontal defects. Key words:Tomography, volume computed, dental radiovisiography, periodontal diseases. PMID:24558524

  10. Latent feature representation with depth directional long-term recurrent learning for breast masses in digital breast tomosynthesis.

    PubMed

    Kim, Dae Hoe; Kim, Seong Tae; Chang, Jung Min; Ro, Yong Man

    2017-02-07

    Characterization of masses in computer-aided detection systems for digital breast tomosynthesis (DBT) is an important step to reduce false positive (FP) rates. To effectively differentiate masses from FPs in DBT, discriminative mass feature representation is required. In this paper, we propose a new latent feature representation boosted by depth directional long-term recurrent learning for characterizing malignant masses. The proposed network is designed to encode mass characteristics in two parts. First, 2D spatial image characteristics of DBT slices are encoded as a slice feature representation by convolutional neural network (CNN). Then, depth directional characteristics of masses among the slice feature representations are encoded by the proposed depth directional long-term recurrent learning. In addition, to further improve the class discriminability of latent feature representation, we have devised three objective functions aiming to (a) minimize classification error, (b) minimize intra-class variation within the same class, and (c) preserve feature representation consistency in a central slice. Experimental results have demonstrated that the proposed latent feature representation achieves a higher level of classification performance in terms of receiver operating characteristic (ROC) curves and the area under the ROC curve values compared to performance with feature representation learned by conventional CNN and hand-crafted features.

  11. Accuracy of direct digital radiography for detecting occlusal caries in primary teeth compared with conventional radiography and visual inspection: an in vitro study

    PubMed Central

    Dias da Silva, P R; Martins Marques, M; Steagall, W; Medeiros Mendes, F; Lascala, C A

    2010-01-01

    Objectives The diagnosis of caries lesions is still a matter of concern in dentistry. The diagnosis of dental caries by digital radiography has a number of advantages over conventional radiography; however, this method has not been explored fully in the field of paediatric dentistry. This in vitro research evaluated the accuracy of direct digital radiography compared with visual inspection and conventional radiography in the diagnosis of occlusal caries lesions in primary molars. Methods 50 molars were selected and evaluated under standardized conditions by 2 previously calibrated examiners according to 3 diagnostic methods (visual inspection, conventional radiography and direct digital radiography). Direct digital radiographs were obtained with the Dixi3 system (Planmeca, Helsinki, Finland) and the conventional radiographs with InSight film (Kodak Eastman Co., Rochester, NY). The images were scored and a reference standard was obtained histologically. The interexaminer reliability was calculated using Cohen's kappa test and the specificity, sensitivity and accuracy of the methods were calculated. Results Examiner reliability was good. For lesions limited to the enamel, visual inspection showed significantly higher sensitivity and accuracy than both radiographic methods, but no significant difference was found in specificity. For teeth with dentinal caries, no significant differences were found for any parameter when comparing visual and radiographic evaluation. Conclusions Although less accurate than the visual method for detecting caries lesions confined to the enamel, the direct digital radiographic method is as effective as conventional radiographic examination and visual inspection of primary teeth with occlusal caries when the dentine is involved. PMID:20729186

  12. Multi-DSP and FPGA based Multi-channel Direct IF/RF Digital receiver for atmospheric radar

    NASA Astrophysics Data System (ADS)

    Yasodha, Polisetti; Jayaraman, Achuthan; Kamaraj, Pandian; Durga rao, Meka; Thriveni, A.

    2016-07-01

    Modern phased array radars depend highly on digital signal processing (DSP) to extract the echo signal information and to accomplish reliability along with programmability and flexibility. The advent of ASIC technology has made various digital signal processing steps to be realized in one DSP chip, which can be programmed as per the application and can handle high data rates, to be used in the radar receiver to process the received signal. Further, recent days field programmable gate array (FPGA) chips, which can be re-programmed, also present an opportunity to utilize them to process the radar signal. A multi-channel direct IF/RF digital receiver (MCDRx) is developed at NARL, taking the advantage of high speed ADCs and high performance DSP chips/FPGAs, to be used for atmospheric radars working in HF/VHF bands. Multiple channels facilitate the radar t be operated in multi-receiver modes and also to obtain the wind vector with improved time resolution, without switching the antenna beam. MCDRx has six channels, implemented on a custom built digital board, which is realized using six numbers of ADCs for simultaneous processing of the six input signals, Xilinx vertex5 FPGA and Spartan6 FPGA, and two ADSPTS201 DSP chips, each of which performs one phase of processing. MCDRx unit interfaces with the data storage/display computer via two gigabit ethernet (GbE) links. One of the six channels is used for Doppler beam swinging (DBS) mode and the other five channels are used for multi-receiver mode operations, dedicatedly. Each channel has (i) ADC block, to digitize RF/IF signal, (ii) DDC block for digital down conversion of the digitized signal, (iii) decoding block to decode the phase coded signal, and (iv) coherent integration block for integrating the data preserving phase intact. ADC block consists of Analog devices make AD9467 16-bit ADCs, to digitize the input signal at 80 MSPS. The output of ADC is centered around (80 MHz - input frequency). The digitized data is fed

  13. Programmable electronic synthesized capacitance

    NASA Technical Reports Server (NTRS)

    Kleinberg, Leonard L. (Inventor)

    1987-01-01

    A predetermined and variable synthesized capacitance which may be incorporated into the resonant portion of an electronic oscillator for the purpose of tuning the oscillator comprises a programmable operational amplifier circuit. The operational amplifier circuit has its output connected to its inverting input, in a follower configuration, by a network which is low impedance at the operational frequency of the circuit. The output of the operational amplifier is also connected to the noninverting input by a capacitor. The noninverting input appears as a synthesized capacitance which may be varied with a variation in gain-bandwidth product of the operational amplifier circuit. The gain-bandwidth product may, in turn, be varied with a variation in input set current with a digital to analog converter whose output is varied with a command word. The output impedance of the circuit may also be varied by the output set current. This circuit may provide very small ranges in oscillator frequency with relatively large control voltages unaffected by noise.

  14. A Digital Image-Based Discrete Fracture Network Model and Its Numerical Investigation of Direct Shear Tests

    NASA Astrophysics Data System (ADS)

    Wang, Peitao; Cai, Meifeng; Ren, Fenhua; Li, Changhong; Yang, Tianhong

    2017-07-01

    This paper develops a numerical approach to determine the mechanical behavior of discrete fractures network (DFN) models based on digital image processing technique and particle flow code (PFC2D). A series of direct shear tests of jointed rocks were numerically performed to study the effect of normal stress, friction coefficient and joint bond strength on the mechanical behavior of joint rock and evaluate the influence of micro-parameters on the shear properties of jointed rocks using the proposed approach. The complete shear stress-displacement curve of the DFN model under direct shear tests was presented to evaluate the failure processes of jointed rock. The results show that the peak and residual strength are sensitive to normal stress. A higher normal stress has a greater effect on the initiation and propagation of cracks. Additionally, an increase in the bond strength ratio results in an increase in the number of both shear and normal cracks. The friction coefficient was also found to have a significant influence on the shear strength and shear cracks. Increasing in the friction coefficient resulted in the decreasing in the initiation of normal cracks. The unique contribution of this paper is the proposed modeling technique to simulate the mechanical behavior of jointed rock mass based on particle mechanics approaches.

  15. Social work practice in the digital age: therapeutic e-mail as a direct practice methodology.

    PubMed

    Mattison, Marian

    2012-07-01

    The author addresses the risks and benefits of incorporating therapeutic e-mail communication into clinical social work practice. Consumer demand for online clinical services is growing faster than the professional response. E-mail, when used as an adjunct to traditional meetings with clients, offers distinct advantages and risks. Benefits include the potential to reach clients in geographically remote and underserved communities, enhancing and extending the therapeutic relationship and improving treatment outcomes. Risks include threats to client confidentiality and privacy, liability coverage for practitioners, licensing jurisdiction, and the lack of competency standards for delivering e-mail interventions. Currently, the social work profession does not have adequate instructive guidelines and best-practice standards for using e-mail as a direct practice methodology. Practitioners need (formal) academic training in the techniques connected to e-mail exchanges with clients. The author describes the ethical and legal risks for practitioners using therapeutic e-mail with clients and identifies recommendations for establishing best-practice standards.

  16. The rise of digital direct-to-consumer advertising?: Comparison of direct-to-consumer advertising expenditure trends from publicly available data sources and global policy implications.

    PubMed

    Mackey, Tim K; Cuomo, Raphael E; Liang, Bryan A

    2015-06-19

    Pharmaceutical marketing is undergoing a major shift in the United States, in part due to new transparency regulations under the healthcare reform act. Changes in pharmaceutical marketing practices include a possible shift from more traditional forms of direct-to-consumer advertising towards emerging use of Internet-based DTCA ("eDTCA") given the growing importance of digital health or "eHealth." Though legally allowed only in the U.S. and New Zealand, eDTCA poses novel regulatory challenges, as it can cross geopolitical boundaries and impact health systems and populations outside of these countries. We wished to assess whether changes in DTCA and eDTCA expenditure trends was occurring using publicly available pharmaceutical marketing data. DTCA data was analyzed to compare trends in aggregate marketing expenditures and to assess if there were statistically significant differences in trends and magnitudes for data sources and DTCA sub-categories (including eDTCA). This was accomplished using regression lines of DTCA trend data and conducting pairwise comparisons of regression coefficients using t-tests. Means testing was utilized for comparing magnitude of DTCA expenditure. Data from multiple data sources indicate that aggregate DTCA expenditures have slightly declined during the period from 2005-2009 and are consistent with results from other studies. For DTCA sub-categories, television remained the most utilized form of DTCA, though experienced trends of declining expenditures (-13.2 %) similar to other traditional media platforms such as radio (-30.7 %) and outdoor ads (-12.1 %). The only DTCA sub-category that experienced substantial increased expenditures was eDTCA (+109.0 %) and it was the only medium that had statistically significant differences in its marketing expenditure trends compared to other DTCA sub-categories. Our study indicates that traditional DTCA marketing may be on the decline. Conversely, the only DTCA sub-category that experienced

  17. Airborne hyperspectral surface and cloud bi-directional reflectivity observations in the Arctic using a commercial, digital camera

    NASA Astrophysics Data System (ADS)

    Ehrlich, A.; Bierwirth, E.; Wendisch, M.; Herber, A.; Gayet, J.-F.

    2011-09-01

    Spectral radiance measurements by a digital single-lens reflex camera were used to derive the bi-directional reflectivity of clouds and different surfaces in the Arctic. The camera has been calibrated radiometrically and spectrally to provide accurate radiance measurements with high angular resolution. A comparison with spectral radiance measurements with the SMART-Albedometer showed an agreement within the uncertainties of both instruments. The bi-directional reflectivity in terms of the hemispherical directional reflectance factor HDRF was obtained for sea ice, ice free ocean and clouds. The sea ice, with an albedo of ρ = 0.96, showed an almost isotropic HDRF, while sun glint was observed for the ocean HDRF (ρ = 0.12). For the cloud observations with ρ = 0.62, the fog bow - a backscatter feature typically for scattering by liquid water droplets - was covered by the camera. For measurements above a heterogeneous stratocumulus clouds, the required number of images to obtain a mean HDRF which clearly exhibits the fog bow has been estimated with about 50 images (10 min flight time). A representation of the HDRF as function of the scattering angle only reduces the image number to about 10 (2 min flight time). The measured cloud and ocean HDRF have been compared to radiative transfer simulations. The ocean HDRF simulated with the observed surface wind speed of 9 m s-1 agreed best with the measurements. For the cloud HDRF, the best agreement was obtained by a broad and weak fog bow simulated with a cloud droplet effective radius of Reff = 4 μm. This value agrees with the particle sizes from in situ measurements and retrieved from the spectral radiance of the SMART-Albedometer.

  18. Effect of NaOH concentration on structural, surface and antibacterial activity of CuO nanorods synthesized by direct sonochemical method

    NASA Astrophysics Data System (ADS)

    Sonia, S.; Jayram, Naidu Dhanpal; Suresh Kumar, P.; Mangalaraj, D.; Ponpandian, N.; Viswanathan, C.

    2014-02-01

    Highly efficient Copper oxide (CuO) nanorods were synthesized by using one step sonochemical method under room temperature with change in NaOH concentration. XRD confirms the prepared nanorods are in pure monoclinic phase with lattice constants a = 4.68 Å, b = 3.42 Å, and c = 5.13 Å and FESEM analysis reveals an average diameter of 50-100 nm. Optical absorption spectra exhibits the strong blue shift compared with bulk and the bandgap increases with decreasing the size of the nanorods which is due to the nanosize effect. The composition of CuO nanorods were characterized by Fourier Transform Infra-Red spectroscopy (FTIR) which confirms the formation of monoclinic phase of CuO and the Thermal analysis was done by Thermo Gravimetric Analysis (TGA). The antibacterial properties of copper oxide nanorods were investigated using human pathogens and was compared based on diameter of inhibition zone using agar well diffusion method. The synthesized copper oxide nanostructures show excellent antibacterial activity against Salmonella typhimurium than Staphylococcus aureus strain.

  19. Direct atomic-level observation and chemical analysis of ZnSe synthesized by in situ high-throughput reactive fiber drawing.

    PubMed

    Hou, Chong; Jia, Xiaoting; Wei, Lei; Stolyarov, Alexander M; Shapira, Ofer; Joannopoulos, John D; Fink, Yoel

    2013-03-13

    We demonstrate a high-throughput method for synthesizing zinc selenide (ZnSe) in situ during fiber drawing. Central to this method is a thermally activated chemical reaction occurring across multiple interfaces between alternately layered elemental zinc- (Zn-) and selenium- (Se-) rich films embedded in a preform and drawn into meters of fiber at a temperature well below the melting temperature of either Zn or ZnSe. By depositing 50 nm thick layers of Zn interleaved between 1 μm thick Se layers, a controlled breakup of the Zn sheet is achieved, thereby enabling a complete and controlled chemical reaction. The thermodynamics and kinetics of this synthesis process are studied using thermogravimetric analysis and differential scanning calorimetry, and the in-fiber compound is analyzed by a multiplicity of materials characterization tools, including transmission electron microscopy, Raman microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction, all resulting in unambiguous identification of ZnSe as the compound produced from the reactive fiber draw. Furthermore, we characterize the in-fiber ZnSe/Se97S3 heterojunction to demonstrate the prospect of ZnSe-based fiber optoelectronic devices. The ability to synthesize new compounds during fiber drawing at nanometer scale precision and to characterize them at the atomic-level extends the architecture and materials selection compatible with multimaterial fiber drawing, thus paving the way toward more complex and sophisticated functionality.

  20. Digital printing

    NASA Astrophysics Data System (ADS)

    Sobotka, Werner K.

    1997-02-01

    Digital printing is described as a tool to replace conventional printing machines completely. Still this goal was not reached until now with any of the digital printing technologies to be described in the paper. Productivity and costs are still the main parameters and are not really solved until now. Quality in digital printing is no problem anymore. Definition of digital printing is to transfer digital datas directly on the paper surface. This step can be carried out directly or with the use of an intermediate image carrier. Keywords in digital printing are: computer- to-press; erasable image carrier; image carrier with memory. Digital printing is also the logical development of the new digital area as it is pointed out in Nicholas Negropotes book 'Being Digital' and also the answer to networking and Internet technologies. Creating images text and color in one country and publishing the datas in another country or continent is the main advantage. Printing on demand another big advantage and last but not least personalization the last big advantage. Costs and being able to coop with this new world of prepress technology is the biggest disadvantage. Therefore the very optimistic growth rates for the next few years are really nonexistent. The development of complete new markets is too slow and the replacing of old markets is too small.

  1. Automated image registration in semiconductor industry: a case study in the direct-to-digital holography inspection system

    NASA Astrophysics Data System (ADS)

    Dai, X. L.; Hunt, Martin A.

    2003-05-01

    Automated image registration based on pattern recognition is a critical procedure in many applications of machine vision and is essential for accurate navigation and change detection. In this paper, an overview of the specific applications of image registration in wafer inspection is given, followed by a case study in the application of image registration for direct to digital holography (DDH) wafer inspection. A complete system of novel algorithms for holographic image capable of accepting a variety of data streams as inputs: (1) complex frequency data; (2) complex spatial data; (3) magnitude of data extracted from holograms; (4) phase data extracted from holograms; and (5) intensity-only data. This flexibility facilitates the development of faster, more reliable, and more efficient DDH processing systems, which is important in system optimization and production. In particular, the system enables the use of the full complex wavefront, which contains both reflectance and structural topology information, in the registration process. The added information contained in the wavefront can be utilized for increased robustness and computational efficiency. Both the theory and implementation of the proposed registration system are briefly described within the framework of DDH processing for wafer inspection tasks. Several examples of defect detection and wafer alignment are given with estimates of accuracy and robustness.

  2. Digital selective fabrication of micro/nano-composite structured TiO2 nanorod arrays by laser direct writing

    NASA Astrophysics Data System (ADS)

    Jiang, Wei; He, Xiaoning; Liu, Hongzhong; Yin, Lei; Shi, Yongsheng; Ding, Yucheng

    2014-11-01

    In this article, we report on the digital selective fabrication of micro/nano-composite structured TiO2 nanorod arrays by laser direct writing. The pattern of TiO2 nanorod arrays can be easily designed and fabricated by laser scanning technology integrated with a computer-aided design system, which allows a high degree of freedom corresponding to the various pattern design demands. The approach basically involves the hydrothermal growth of TiO2 nanorod arrays on a transparent conductive substrate, the micropattern of TiO2 nanorod arrays and surface fluorination treatment. With these micro/nano-composite TiO2 nanorod array based films, we have demonstrated superhydrophilic patterned TiO2 nanorod arrays with rapid water spreading ability and superhydrophobic patterned TiO2 nanorod arrays with an excellent droplet bouncing effect and a good self-cleaning performance. The dynamic behaviours of the water droplets observed on the patterned TiO2 nanorod arrays were demonstrated by experiments and simulated by a finite element method. The approaches we will show are expected to provide potential applications in fields such as self-cleaning, surface protection, anticrawling and microfluidic manipulation.

  3. Direct Numerical Simulation of Fracture Behaviour for Random Short Wood Fibres Reinforced Composites, Comparison with Digital Image Correlation Experiments

    NASA Astrophysics Data System (ADS)

    Shen, M.; Touchard, F.; Bezine, G.; Brillaud, J.

    2010-06-01

    The work is to predict fracture behaviour of bio-composites from the tensile properties of its components. In this work, we have realized a direct numerical simulation of fracture behaviour for random short spruce fibers reinforced composites. For calculations, wood fibers have been considered as linear elastic bodies, polypropylene matrix as an elastic-plastic material. Then, numerical results have been compared with experimental results that have been obtained by digital image correlation. This comparison indicates that random fiber FE model of random short spruce fibers reinforced composites can be able to fairly reflect the influence of random fibers microstructure in the composite on its fracture behavior. The calculation of both random fiber and homogeneous FE model and their comparison with experiments show that the average values of J-integral in a region in the front of the crack tip from both numerical FE models are in good agreement with the average J value of DIC experiment in the same region when the numerical and experimental CT specimens of the short spruce fiber reinforced composite are subjected to the same extension at their loading point.

  4. Direct Digital Control Study.

    DTIC Science & Technology

    1985-02-01

    please attach additional pages to answer this question. 6. What is the "rule of thumb" used to calculate the number of DDC control loops and 1/0 points...I ’ : ’ ~ 2’, . Vkt ; .nw]i.<[[I’ S, ,ten,m Service Company would like to receive a copy of i I ication. Should additional information be required

  5. P(O)R2-directed Pd-catalyzed C-H functionalization of biaryl derivatives to synthesize chiral phosphorous ligands.

    PubMed

    Hu, Rong-Bin; Wang, Hong-Li; Zhang, Hong-Yu; Zhang, Heng; Ma, Yan-Na; Yang, Shang-Dong

    2014-01-01

    Chiral phosphorus ligands have been widely used in transition metal-catalyzed asymmetric reactions. Herein, we report a new synthesis approach of chiral biaryls containing a phosphorus moiety using P(O)R2-directed Pd-catalyzed C-H activation; the functionalized products are produced with good enantioselectivity.

  6. Metal- and ligand-directed one-pot syntheses, crystal structures, and properties of novel oxo-centered tetra- and hexametallic clusters.

    PubMed

    Saalfrank, Rolf W; Reimann, Uwe; Göritz, Mareike; Hampel, Frank; Scheurer, Andreas; Heinemann, Frank W; Büschel, Michael; Daub, Jörg; Schünemann, Volker; Trautwein, Alfred X

    2002-08-16

    Starting from closely related metal-ligand combinations, completely different oligomeric metal clusters are synthesized. Whereas, picoline-tetrazolylamide HL(1) (1) and zinc or nickel acetate afforded [2x2] grids [M(4)(L(1))(8)] (2), slightly different N-(2-methylthiazole-5-yl)-thiazole-2-carboxamide HL(2) (5 a) and nickel acetate yielded the monometallic complex [Ni(L(2))(2)(OH(2))(2)] (6). In contrast, reaction of 5 a with zinc acetate produced the tetrametallic zinc cluster [Zn(4)O(L(2))(4)(OAc)(2)] (7). Even more surprising, when 3-methyl-substituted HL(3) (5 b) instead of 2-methyl-substituted HL(2) (5 a) was allowed to react under identical conditions with zinc acetate, the cluster [Zn(4)O(L(3))(4)Cl(2)] (8) crystallized from dichloromethane. Clusters 7 and 8 are isostructural. As for 7, in 8 two of the edges of the tetrahedron of zinc ions are doubly bridged, two are singly bridged, and the other two are nonbridged. On the other hand, when iron(II) acetate under aerobic conditions was allowed to react with 5 a, the unprecedented complex [[Fe(3)O(L(2))(2)(OAc)(4)](2)O] (9) was isolated. Cluster 9 is composed of two trimetallic, triangular mu(3)-O(2-)-centered [Fe(3)O(L(2))(2)(OAc)(4)](+) modules, linked by an almost linear mu(2)-O(2-) bridge. The Mössbauer spectrum together with cyclic voltammetric and square-wave voltammetric measurements of 9 are reported, and 6-9 were characterized unequivocally by single-crystal X-ray structure analyses.

  7. The Enhanced Workflow and Efficiency of the Wireless Local Area Network (WLAN)-Based Direct Digital Radiography (DDR) Portable Radiography.

    PubMed

    Ngan, Tsz-Lung; Wong, Edward Ting-Hei; Ng, Kris Lap-Shun; Jeor, Patrick Kwok-Shing; Lo, Gladys Goh

    2015-06-01

    With the implementation of the PACS in the hospital, there is an increasing demand from the clinicians for immediate access and display of radiological images. Recently, our hospital has installed the first wireless local area network (WLAN)-based direct digital radiography (DDR) portable radiography system. The DDR portable radiography system allows wireless retrieval of modality worklist and wireless transmission of portable X-ray image on the console to the Picture Archiving and Communication System (PACS), via WLAN connection of wireless fidelity (Wi-Fi). The aim of this study was to analyze the workflow and performance between the WLAN-based DDR portable radiography system and the old practice using conventional portable X-ray machine with computed radiography (CR) system. A total of 190 portable chest X-ray examinations were evaluated and timed, using the conventional portable X-ray machine with CR from March to April of 2012 and using the new DDR portable radiography system on December of 2012 (n = 97 for old system and n = 93 for DDR portable system). The time interval of image becoming available to the PACS using the WLAN-based DDR portable radiography system was significantly shorter than that of the old practice using the conventional portable X-ray machine with CR (6.8 ± 2.6 min for DDR portable system; 23 ± 10.2 min for old system; p < 0.0001), with the efficiency improved by 70 %. The implementation of the WLAN-based DDR portable radiography system can enhance the workflow of portable radiography by reduction of procedural steps.

  8. Exploration of strategies for implementation of screen-printed mercuric iodide converters in direct detection AMFPIs for digital breast tomosynthesis

    NASA Astrophysics Data System (ADS)

    Antonuk, Larry E.; El-Mohri, Youcef; Zhao, Qihua; Jiang, Hao

    2017-03-01

    Digital breast tomosynthesis (DBT) has become an increasingly important tool in the diagnosis of breast disease. For those DBT imaging systems based on active matrix, flat-panel imager (AMFPI) arrays, the incident radiation is detected directly or indirectly by means of an a-Se or CsI:Tl x-ray converter, respectively. While all AMFPI DBT devices provide clinically useful volumetric information, their performance is limited by the relatively modest average signal generated per interacting X ray by present converters compared to the electronic additive noise of the system. To address this constraint, we are pursuing the development of a screen-printed form of mercuric iodide (SP HgI2) which has demonstrated considerably higher sensitivities (i.e., larger average signal per interacting X ray) than those of conventional a-Se and CsI:Tl converters, as well as impressive DQE and MTF performance under mammographic irradiation conditions. A converter offering such enhanced sensitivity would greatly improve signal-to-noise performance and facilitate quantum-limited imaging down to significantly lower exposures than present AMFPI DBT systems. However, before this novel converter material can be implemented practically, challenges associated with SP HgI2 must be addressed. Most significantly, high levels of charge trapping (which lead to image lag as well as fall-off in DQE at higher exposures) need to be reduced - while improving the uniformity in pixel-to-pixel signal response as well as maintaining low dark current and otherwise favorable DQE performance. In this paper, a pair of novel strategies for overcoming the challenge of charge trapping in SP HgI2 converters are described, and initial results from empirical and calculational studies of these strategies are reported.

  9. Hearing impaired children's preference for, and performance with, four combinations of directional microphone and digital noise reduction technology.

    PubMed

    Pittman, Andrea L; Hiipakka, Mollie M

    2013-10-01

    Before advanced noise-management features can be recommended for use in children with hearing loss, evidence regarding their ability to use these features to optimize speech perception is necessary. The purpose of this study was to examine the relation between children's preference for, and performance with, four combinations of noise-management features in noisy listening environments. Children with hearing loss were asked to repeat short sentences presented in steady-state noise or in multitalker babble while wearing ear-level hearing aids. The aids were programmed with four memories having an orthogonal arrangement of two noise-management features. The children were also asked to indicate the hearing aid memory that they preferred in each of the listening conditions both initially and after a short period of use. Fifteen children between the ages of 8 and 12 yr with moderate hearing losses, bilaterally. The children's preference for noise management aligned well with their performance for at least three of the four listening conditions. The configuration of noise-management features had little effect on speech perception with the exception of reduced performance for speech originating from behind the child while in a directional hearing aid setting. Additionally, the children's preference appeared to be governed by listening comfort, even under conditions for which a benefit was not expected such as the use of digital noise reduction in the multitalker babble conditions. The results serve as evidence in support of the use of noise-management features in grade-school children as young as 8 yr of age. American Academy of Audiology.

  10. Intravascular ultrasound versus digital subtraction angiography: direct comparison of intraluminal diameter measurements in pediatric and adolescent imaging.

    PubMed

    Gill, Anne E; Ciszak, Tadi; Braun, Hayley; Hawkins, C Matthew

    2017-04-01

    Intravascular ultrasound (IVUS) allows intraluminal imaging of blood vessels rather than the one-dimensional luminal outline depicted by digital subtraction angiography (DSA). Despite extensive literature in multiple adult vascular diseases, IVUS has not been directly compared to DSA in pediatric and adolescent vascular pathologies. The purpose of this manuscript is to compare absolute luminal diameter measurements obtained via IVUS and DSA during a variety of pediatric endovascular procedures. We conducted a retrospective review of all pediatric and adolescent endovascular procedures from October 2014 to March 2016 in which IVUS and DSA were used. We compared the vessel diameter measurements and analyzed them using SAS software with a paired t-test. There were 102 total measurements (DSA = 56; IVUS = 56; 22 procedures; 20 patients). On average, IVUS measured 0.6 ± 2.1 mm larger than DSA (95% confidence interval [CI] -0.01 to 1.12; P = 0.06; r = 0.90). When venous compression syndrome (May-Thurner, Nutcracker, superior vena cava syndrome) measurements were excluded, IVUS measured 0.7 ± 1.6 mm larger than DSA (95% CI 0.14 to 1.18; P = 0.01; r = 0.93). When venous compression syndrome measurements were evaluated separately, IVUS measured 0.3 ± 3.0 mm larger than DSA (95% CI -1.16 to 1.82; P = 0.65; r = 0.45). Overall, IVUS measurements were slightly larger than DSA measurements in all data subsets. Absolute vessel diameter measurements obtained with IVUS in the pediatric and adolescent population are statistically significantly larger than those obtained using DSA when excluding venous compression syndromes. In venous compression syndromes, IVUS might provide a more accurate representation of vessel compression and diameter than DSA.

  11. Influence of immobilization and sensory re-education on the sensory recovery after reconstruction of digital nerves with direct suture or muscle-in-vein conduits.

    PubMed

    Manoli, Theodora; Schiefer, Jennifer Lynn; Schulz, Lukas; Fuchsberger, Thomas; Schaller, Hans-Eberhard

    2016-02-01

    The influence of duration of immobilization and postoperative sensory re-education on the final outcome after reconstruction of digital nerves with direct suture or muscle-in-vein conduits was investigated. The final sensory outcome of 35 patients with 41 digital nerve injuries, who either underwent a direct suture (DS) or a nerve reconstruction with muscle-in-vein conduits (MVC), was assessed the earliest 12 months postoperatively using static and moving two-point discrimination as well as Semmes-Weinstein monofilaments. There was no significant difference in sensory recovery in cases with an immobilization of 3-7 days versus 10 days in the DS or MVC group. Moreover, no statistically significant difference in sensory recovery was found in cases receiving postoperative sensory re-education versus those not receiving in the DS or MVC group. An early mobilization does not seem to have a negative impact on the final outcome after digital nerve reconstruction. The effect of sensory re-education after digital nerve reconstruction should be reconsidered.

  12. Crystalline mesoporous tungsten oxide nanoplate monoliths synthesized by directed soft template method for highly sensitive NO{sub 2} gas sensor applications

    SciTech Connect

    Hoa, Nguyen Duc; Duy, Nguyen Van; Hieu, Nguyen Van

    2013-02-15

    Graphical abstract: Display Omitted Highlights: ► Mesoporous WO{sub 3} nanoplate monoliths were obtained by direct templating synthesis. ► Enable effective accession of the analytic molecules for the sensor applications. ► The WO{sub 3} sensor exhibited a high performance to NO{sub 2} gas at low temperature. -- Abstract: Controllable synthesis of nanostructured metal oxide semiconductors with nanocrystalline size, porous structure, and large specific surface area is one of the key issues for effective gas sensor applications. In this study, crystalline mesoporous tungsten oxide nanoplate-like monoliths with high specific surface areas were obtained through instant direct-templating synthesis for highly sensitive nitrogen dioxide (NO{sub 2}) sensor applications. The copolymer soft template was converted into a solid carbon framework by heat treatment in an inert gas prior to calcinations in air to sustain the mesoporous structure of tungsten oxide. The multidirectional mesoporous structures of tungsten oxide with small crystalline size, large specific surface area, and superior physical characteristics enabled the rapid and effective accession of analytic gas molecules. As a result, the sensor response was enhanced and the response and recovery times were reduced, in which the mesoporous tungsten oxide based gas sensor exhibited a superior response of 21,155% to 5 ppm NO{sub 2}. In addition, the developed sensor exhibited selective detection of low NO{sub 2} concentration in ammonia and ethanol at a low temperature of approximately 150 °C.

  13. Water induced protonation of amine-terminated micelles for direct syntheses of ZnO quantum dots and their cytotoxicity towards cancer

    NASA Astrophysics Data System (ADS)

    Zhang, Yinzhu; Wang, Huangping; Jiang, Hui; Wang, Xuemei

    2012-05-01

    This work designs a new strategy for the direct synthesis of different zinc oxide (ZnO) nanostructures at low temperatures. Micelles of dodecylamine (DDA) assembled in an ethanol-water system have been explored as a template to direct the growth of the ZnO nanostructures. The key species for the formation of the ZnO nanostructures, OH-, can be provided by the water-induced protonation of DDA. The pH of the reaction micro-environment can be regulated by changing the input amount of water and DDA. By controlling the reaction temperature and pH, various ZnO nanostructures, i.e. quantum dots with green or yellow-green emissions, have been prepared. The relationship of the optical properties and the synthetic conditions has been further discussed. This strategy realizes the convenient preparation of ZnO QDs, indicating the potential prospects in the nanotechnology field for their low-cost synthesis. Meanwhile, the cellular toxicity study of ZnO nanoparticles toward cancer cells, including leukemia K562 and K562/A02 cells as well as HepG2 cells, indicates a selective cytotoxic effect of ZnO QDs against a broad range of human cancer cell lines.

  14. Frequency of Penetration of the Digital Flexor Tendon Sheath and Distal Interphalangeal Joint Using a Direct Endoscopic Approach to the Navicular Bursa in Horses

    PubMed Central

    Taylor, Sarah Elizabeth; García, Eugenio Cillán; Reardon, Richard J.M.

    2016-01-01

    Objective To evaluate the frequency of inadvertent penetration of the digital flexor tendon sheath (DFTS) and/or distal interphalangeal joint (DIPJ) when using a direct endoscopic approach to the navicular bursa, and to evaluate an alternate direct approach to the navicular bursa. Study Design Cadaveric study. Sample Population Equine cadaver limbs (n = 40 for direct; n = 12 for alternate approach). Methods Four surgeons performed the direct endoscopic approach to the navicular bursa on 10 limbs each. Frequencies of inadvertent synovial penetration and iatrogenic damage were compared between surgeons. Use of an alternate direct approach, adopting a straight parasagittal trajectory, was evaluated by 2 surgeons. Results Inadvertent synovial penetration occurred in 45% of limbs (DFTS 37.5%; DIPJ 17.5%; and both structures 10%). Successful bursa entry was achieved on the first attempt in 45% of limbs. Significant variation in frequency of inadvertent synovial penetration was observed between surgeons (range 10–80%). Inadvertent synovial penetration did not occur when using the alternate direct technique. Iatrogenic damage to navicular bone fibrocartilage and/or deep digital flexor tendon occurred in 55% of limbs using the direct endoscopic approach and in 0% of limbs using the alternate direct approach. Conclusion Because of the considerable risk of inadvertent penetration of the DFTS and/or the DIPJ when making a direct endoscopic approach to the navicular bursa, it is advisable to investigate for inadvertent penetration when treating navicular bursa sepsis using a direct approach. The alternate direct technique may reduce the risk of inadvertent penetration; however, the view within the bursa may be restricted. PMID:26971252

  15. Frequency of Penetration of the Digital Flexor Tendon Sheath and Distal Interphalangeal Joint Using a Direct Endoscopic Approach to the Navicular Bursa in Horses.

    PubMed

    Kane-Smyth, Justine; Taylor, Sarah Elizabeth; García, Eugenio Cillán; Reardon, Richard J M

    2016-04-01

    To evaluate the frequency of inadvertent penetration of the digital flexor tendon sheath (DFTS) and/or distal interphalangeal joint (DIPJ) when using a direct endoscopic approach to the navicular bursa, and to evaluate an alternate direct approach to the navicular bursa. Cadaveric study. Equine cadaver limbs (n = 40 for direct; n = 12 for alternate approach). Four surgeons performed the direct endoscopic approach to the navicular bursa on 10 limbs each. Frequencies of inadvertent synovial penetration and iatrogenic damage were compared between surgeons. Use of an alternate direct approach, adopting a straight parasagittal trajectory, was evaluated by 2 surgeons. Inadvertent synovial penetration occurred in 45% of limbs (DFTS 37.5%; DIPJ 17.5%; and both structures 10%). Successful bursa entry was achieved on the first attempt in 45% of limbs. Significant variation in frequency of inadvertent synovial penetration was observed between surgeons (range 10-80%). Inadvertent synovial penetration did not occur when using the alternate direct technique. Iatrogenic damage to navicular bone fibrocartilage and/or deep digital flexor tendon occurred in 55% of limbs using the direct endoscopic approach and in 0% of limbs using the alternate direct approach. Because of the considerable risk of inadvertent penetration of the DFTS and/or the DIPJ when making a direct endoscopic approach to the navicular bursa, it is advisable to investigate for inadvertent penetration when treating navicular bursa sepsis using a direct approach. The alternate direct technique may reduce the risk of inadvertent penetration; however, the view within the bursa may be restricted. © 2016 The Authors. Veterinary Surgery published by Wiley Periodicals Inc. on behalf of The American College of Veterinary Surgeons.

  16. A novel 3D Ag(I)-MOF: Surfactant-directed syntheses and catalytic degradation of o/m/p-Nitrophenol

    NASA Astrophysics Data System (ADS)

    Wu, Xue-Qian; Wen, Guo-Xuan; Wu, Ya-Pan; Dong, Wen-Wen; Zhao, Jun; Li, Dong-Sheng

    2016-10-01

    For the first time, sodium caprylate has been investigated to direct the crystal growth of 3D Ag-MOF, [Ag2(ddcba)(4,4‧-bipy)2] (1), constructing from 3,5-(di(2‧,5‧-dicarboxylphenyl)benozoic acid and 4,4‧-bipy. The single crystal diffraction analyses shows that complex 1 possess 3D neutral framework with a three-connected ThSi2 (103-b) topology. Compound 1 exhibits predominant catalytic activity towards the degradation of o-Nitrophenol (ONP), m-Nitrophenol (MNP) and p-Nitrophenol (PNP) in aqueous solution. The kinetics of such catalytic degradation reactions was also studied.

  17. Achieving a slippery, liquid-infused porous surface with anti-icing properties by direct deposition of flame synthesized aerosol nanoparticles on a thermally fragile substrate

    NASA Astrophysics Data System (ADS)

    Juuti, Paxton; Haapanen, Janne; Stenroos, Christian; Niemelä-Anttonen, Henna; Harra, Juha; Koivuluoto, Heli; Teisala, Hannu; Lahti, Johanna; Tuominen, Mikko; Kuusipalo, Jurkka; Vuoristo, Petri; Mäkelä, Jyrki M.

    2017-04-01

    Slippery, liquid-infused porous surfaces offer a promising route for producing omniphobic and anti-icing surfaces. Typically, these surfaces are made as a coating with expensive and time consuming assembly methods or with fluorinated films and oils. We report on a route for producing liquid-infused surfaces, which utilizes a liquid precursor fed oxygen-hydrogen flame to produce titania nanoparticles deposited directly on a low-density polyethylene film. This porous nanocoating, with thickness of several hundreds of nanometers, is then filled with silicone oil. The produced surfaces are shown to exhibit excellent anti-icing properties, with an ice adhesion strength of ˜12 kPa, which is an order of magnitude improvement when compared to the plain polyethylene film. The surface was also capable of maintaining this property even after cyclic icing testing.

  18. Inverse filtering approach to measure directional in-plane modulation transfer function using a sphere phantom for a digital tomosynthesis system.

    PubMed

    Lee, Changwoo; Baek, Jongduk

    2017-07-24

    We propose a method to measure the directional in-plane modulation transfer function (MTF) of a digital tomosynthesis system using a sphere phantom. To assess the spatial resolution of an in-plane image of the tomosynthesis system, projection data of a sphere phantom were generated within a limited data acquisition range of 40°, and reconstructed by the FDK algorithm. To measure the in-plane MTF, we divided the Fourier transform of the reconstructed sphere phantom by that of the ideal sphere phantom, and then performed plane integral along the fz-direction. When dividing, small values in the denominator can introduce estimation errors, and these errors were reduced by the proposed method. To evaluate the performance of the proposed method, the in-plane MTF estimated by simulation and experimental data was compared to the ideal in-plane MTF generated by computer simulations using a point object. For quantitative evaluation, we measured frequency values at half-maximum and full-maximum of the directional in-plane MTF along the three different directions (i.e., f0° -, f30° -, and f60° -directions) and compared them with those of the ideal in-plane MTF. Although the sphere phantom has been regarded as an inappropriate object due to the anisotropic characteristics of tomosynthesis image, our results show that the proposed method has a reliable estimation performance, demonstrating the sphere phantom is still suitable for measuring the directional in-plane MTF for a digital tomosynthesis system.

  19. Hybrid one-dimensional nanostructures: one-pot preparation of nanoparticle chains via directed self-assembly of in situ synthesized discrete Au nanoparticles.

    PubMed

    Walter, Marie V; Cheval, Nicolas; Liszka, Olimpia; Malkoch, Michael; Fahmi, Amir

    2012-04-10

    The fabrication of well-defined one-dimensional (1D) arrays is becoming a challenge for the development of the next generation of advanced nanodevices. Herein, a simple concept is proposed for the in situ synthesis and self-assembly of gold nanoparticles (AuNPs) into 1D arrays via a one-step process. The results demonstrated the formation of nanoparticle chains (NPC) with high aspect ratio based on discrete Au nanoparticles stabilized by short thiol ligands. A model was proposed to explain the self-assembly based on the investigation of several parameters such as pH, solvent, temperature, and nature of the ligand on the 1D assembly formation. Hydrogen bonding was identified as a key factor to direct the self-assembly of the hybrid organic-inorganic nanomaterials into the well-defined 1D nanostructures. This simple and cost-effective concept could potentially be extended to the fabrication of a variety of hybrid 1D nanostructures possessing unique physical properties leading to a wide range of applications including catalysis, bionanotechnology, nanoelectronics, and photonics.

  20. Digital Sensor Technology

    SciTech Connect

    Ted Quinn; Jerry Mauck; Richard Bockhorst; Ken Thomas

    2013-07-01

    The nuclear industry has been slow to incorporate digital sensor technology into nuclear plant designs due to concerns with digital qualification issues. However, the benefits of digital sensor technology for nuclear plant instrumentation are substantial in terms of accuracy, reliability, availability, and maintainability. This report demonstrates these benefits in direct comparisons of digital and analog sensor applications. It also addresses the qualification issues that must be addressed in the application of digital sensor technology.

  1. AACR2 and Its Place in the Digital World: Near-Term Solutions and Long-Term Direction.

    ERIC Educational Resources Information Center

    Huthwaite, Ann

    This paper discusses AACR2 (Anglo-American Cataloging Rules, 2nd edition) and its place in the digital world. The first section describes changes in the bibliographic universe since AACR2 was first published in 1978. The second section addresses the perceived shortcomings of AACR2. The third section considers processes for change, including the…

  2. Comparison of digital direct readout radiography with conventional film-screen radiography for the recognition of pneumoconiosis in dust-exposed Chinese workers.

    PubMed

    Mao, Ling; Laney, A Scott; Wang, Mei Lin; Sun, Xiwen; Zhou, Shaowei; Shi, Jin; Shi, Haiyan

    2011-01-01

    Pneumoconiosis in China remains a disease with substantial public health significance. Diagnostic standards for the pneumoconioses are based on traditional film-screen radiography (FSR). However, FSR is increasingly being replaced with digital radiographic imaging, which has become the predominant technology available in Chinese clinical practice. To evaluate the applicability of digital direct readout radiography (DR) images in the recognition of pneumoconioses, we compared the profusion of small opacities and large opacities between FSR and DR radiographs. We enrolled 161 pneumoconioses patients and 31 dust-exposed workers during the course of the study, with FSR and DR images obtained from all participants. Each chest film was interpreted by five readers using the Chinese Diagnostic Criteria classification of radiographs of pneumoconiosis, as were DR images displayed on medical-grade computer monitors. No statistically significant differences were observed when the data were analyzed by small opacity profusion subcategory except for 1/1. The overall intermodality agreement of small opacities was good, with a weighted kappa (κ) of 0.77. DR images with soft copy display are equivalent with respect to image quality and the recognition and classification of small parenchymal lung opacities. Additionally, we observed likeness between modalities with respect to the classification of large opacities. Overall, our study findings demonstrate that in a population of Chinese workers with pneumoconiosis, direct readout digital systems are equivalent to traditional film-screen radiography in the recognition and classification of small pneumoconiotic opacities.

  3. [Correlation between basic imaging properties and subjective evaluations of two digital radiographic X-ray systems based on direct-conversion flat panel detector].

    PubMed

    Sakaguchi, Taro; Katayama, Reiji; Morishita, Junji; Sakai, Shinji; Kuroki, Hidefumi; Ohkubo, Seiji; Maeda, Takashi; Hayabuchi, Naofumi

    2010-11-20

    The purpose of this study was to examine the correlation between the basic imaging properties of two digital radiographic X-ray systems with a direct conversion flat-panel detector and their image qualities, which were evaluated by the observer in hard copy and soft copy studies. The subjective image quality was evaluated and compared in terms of the low-contrast detectability and image sharpness in the two digital radiographic X-ray systems. We applied the radiographs of a contrast detail phantom to the evaluation of low-contrast detectability and analyzed the contrast detail diagrams. Finally, low-contrast detectability was evaluated by the image quality figure (IQF) calculated from the contrast detail diagrams. Also, the subjective image sharpness of human dry bones of two systems was examined and evaluated by the normalized-rank method. The results indicated that System A tended to provide superior subjective image quality compared to System B in both observer studies. We also found high correlations between IQFs and basic imaging properties, such as the noise power spectrum (NPS) and the noise equivalent quantum (NEQ). In conclusion, the low-contrast detectability of the two digital radiographic X-ray systems with a direct conversion flat-panel detector corresponded to the NPS and the NEQ in both outputs (soft copy and hard copy). On the other hand, the subjective image sharpness of human dry bones was affected by their noise properties.

  4. Evaluation of fit and efficiency of CAD/CAM fabricated all-ceramic restorations based on direct and indirect digitalization: a double-blinded, randomized clinical trial.

    PubMed

    Ahrberg, Danush; Lauer, Hans Christoph; Ahrberg, Martin; Weigl, Paul

    2016-03-01

    The aim of this clinical trial was to evaluate the marginal and internal fit of CAD/CAM fabricated zirconia crowns and three-unit fixed dental prostheses (FDPs) resulting from direct versus indirect digitalization. The efficiency of both methods was analyzed. In 25 patients, 17 single crowns and eight three-unit FDPs were fabricated with all-ceramic zirconia using CAD/CAM technology. Each patient underwent two different impression methods; a computer-aided impression with Lava C.O.S. (CAI) and a conventional polyether impression with Impregum pent soft (CI). The working time for each group was recorded. Before insertion, the marginal and internal fit was recorded using silicone replicas of the frameworks. Each sample was cut into four sections and evaluated at four sites (marginal gap, mid-axial wall, axio-occlusal transition, centro-occlusal site) under ×64 magnification. The Mann-Whitney U test was used to detect significant differences between the two groups in terms of marginal and internal fit (α = 0.05). The mean for the marginal gap was 61.08 μm (±24.77 μm) for CAI compared with 70.40 μm (±28.87 μm) for CI, which was a statistically significant difference. The other mean values for CAI and CI, respectively, were as follows in micrometers (± standard deviation): 88.27 (±41.49) and 92.13 (±49.87) at the mid-axial wall; 144.78 (±46.23) and 155.60 (±55.77) at the axio-occlusal transition; and 155.57 (49.85) and 171.51 (±60.98) at the centro-occlusal site. The CAI group showed significantly lower values of internal fit at the centro-occlusal site. A quadrant scan with a computer-aided impression was 5 min 6 s more time efficient when compared with a conventional impression, and a full-arch scan was 1 min 34 s more efficient. Although both direct and indirect digitalization facilitate the fabrication of single crowns and three-unit FDPs with clinically acceptable marginal fit, a significantly better marginal fit was noted with direct

  5. Simultaneous all-optical digital comparator and dual-directional half-subtractor for two-input 40 Gbit/s DPSK signals employing SOAs

    NASA Astrophysics Data System (ADS)

    Zhang, Yin; Lei, Lei; Dong, Jianji; Zhang, Xinliang

    2012-02-01

    A module of simultaneous implementation of all-optical digital comparator and dual-directional half-subtractor is proposed. Proof-of-concept experiment is performed at 40 Gbit/s employing the four-wave mixing and cross gain modulation in three parallel semiconductor optical amplifiers. All output results with over 10 dB extinction ratios, clear and wide open eye diagrams, are obtained without using assistant/holding light beam. All-optical half-adder can also be obtained by adjusting the phase shifter of delay interferometer in the proposed module because of its inherent reconfigurability and flexibility. The module would be a promising digital logic elementary circuit in all-optical networks and computing systems.

  6. One way Doppler Extractor. Volume 2: Digital VCO technique

    NASA Technical Reports Server (NTRS)

    Nossen, E. J.; Starner, E. R.

    1974-01-01

    A feasibility analysis and trade-offs for a one-way Doppler extractor using digital VCO techniques is presented. The method of Doppler measurement involves the use of a digital phase lock loop; once this loop is locked to the incoming signal, the precise frequency and hence the Doppler component can be determined directly from the contents of the digital control register. The only serious error source is due to internally generated noise. Techniques are presented for minimizing this error source and achieving an accuracy of 0.01 Hz in a one second averaging period. A number of digitally controlled oscillators were analyzed from a performance and complexity point of view. The most promising technique uses an arithmetic synthesizer as a digital waveform generator.

  7. TEM Characterization of Nanostructured MgAl2O4 Synthesized by a Direct Conversion Process from gamma-Al2O3

    SciTech Connect

    Al-Sharab, J.F.; Cosandey, F.; Singhal, Amit; Skandan, Ganesh; Bentley, James

    2006-01-01

    Nanostructured MgAl{sub 2}O{sub 4} spinel was synthesized by a direct conversion process from cubic ?-Al2O3. The effect of post-annealing temperature (300C, 500C, and 800C) on MgAl2O4 phase formation was investigated using transmission electron microscopy, selected area electron diffraction (SAED), electron energy loss spectroscopy (EELS), and energy-dispersive spectroscopy (EDS). Relative diffraction intensities as well as lattice parameter measurements from SAED revealed that MgAl2O4 spinel structure starts forming at temperatures as low as 300C. EELS and EDS spectrum images also revealed an increase in elemental homogeneity with increasing annealing temperature. The degree of ordering of Mg and Al between octahedral and tetrahedral sites has been determined from relative diffraction intensities. Results show that annealing to 800C leads to a spinel phase with an order parameter of 0.78.

  8. Portable Speech Synthesizer

    NASA Technical Reports Server (NTRS)

    Leibfritz, Gilbert H.; Larson, Howard K.

    1987-01-01

    Compact speech synthesizer useful traveling companion to speech-handicapped. User simply enters statement on board, and synthesizer converts statement into spoken words. Battery-powered and housed in briefcase, easily carried on trips. Unit used on telephones and face-to-face communication. Synthesizer consists of micro-computer with memory-expansion module, speech-synthesizer circuit, batteries, recharger, dc-to-dc converter, and telephone amplifier. Components, commercially available, fit neatly in 17-by 13-by 5-in. briefcase. Weighs about 20 lb (9 kg) and operates and recharges from ac receptable.

  9. Development of Coriolis mass flowmeter with digital drive and signal processing technology.

    PubMed

    Hou, Qi-Li; Xu, Ke-Jun; Fang, Min; Liu, Cui; Xiong, Wen-Jun

    2013-09-01

    Coriolis mass flowmeter (CMF) often suffers from two-phase flowrate which may cause flowtube stalling. To solve this problem, a digital drive method and a digital signal processing method of CMF is studied and implemented in this paper. A positive-negative step signal is used to initiate the flowtube oscillation without knowing the natural frequency of the flowtube. A digital zero-crossing detection method based on Lagrange interpolation is adopted to calculate the frequency and phase difference of the sensor output signals in order to synthesize the digital drive signal. The digital drive approach is implemented by a multiplying digital to analog converter (MDAC) and a direct digital synthesizer (DDS). A digital Coriolis mass flow transmitter is developed with a digital signal processor (DSP) to control the digital drive, and realize the signal processing. Water flow calibrations and gas-liquid two-phase flowrate experiments are conducted to examine the performance of the transmitter. The experimental results show that the transmitter shortens the start-up time and can maintain the oscillation of flowtube in two-phase flowrate condition.

  10. A multi-directional and multi-scale roughness filter to detect lineament segments on digital elevation models - analyzing spatial objects in R

    NASA Astrophysics Data System (ADS)

    Baumann, Sebastian; Robl, Jörg; Wendt, Lorenz; Willingshofer, Ernst; Hilberg, Sylke

    2016-04-01

    Automated lineament analysis on remotely sensed data requires two general process steps: The identification of neighboring pixels showing high contrast and the conversion of these domains into lines. The target output is the lineaments' position, extent and orientation. We developed a lineament extraction tool programmed in R using digital elevation models as input data to generate morphological lineaments defined as follows: A morphological lineament represents a zone of high relief roughness, whose length significantly exceeds the width. As relief roughness any deviation from a flat plane, defined by a roughness threshold, is considered. In our novel approach a multi-directional and multi-scale roughness filter uses moving windows of different neighborhood sizes to identify threshold limited rough domains on digital elevation models. Surface roughness is calculated as the vertical elevation difference between the center cell and the different orientated straight lines connecting two edge cells of a neighborhood, divided by the horizontal distance of the edge cells. Thus multiple roughness values depending on the neighborhood sizes and orientations of the edge connecting lines are generated for each cell and their maximum and minimum values are extracted. Thereby negative signs of the roughness parameter represent concave relief structures as valleys, positive signs convex relief structures as ridges. A threshold defines domains of high relief roughness. These domains are thinned to a representative point pattern by a 3x3 neighborhood filter, highlighting maximum and minimum roughness peaks, and representing the center points of lineament segments. The orientation and extent of the lineament segments are calculated within the roughness domains, generating a straight line segment in the direction of least roughness differences. We tested our algorithm on digital elevation models of multiple sources and scales and compared the results visually with shaded relief map

  11. Method for synthesizing powder materials

    DOEpatents

    Buss, R.J.; Ho, P.

    1988-01-21

    A method for synthesizing ultrafine powder materials, for example, ceramic and metal powders, comprises admitting gaseous reactants from which the powder material is to be formed into a vacuum reaction chamber maintained at a pressure less than atmospheric and at a temperature less than about 400/degree/K (127/degree/C). The gaseous reactants are directed through a glow discharge provided in the vacuum reaction chamber to form the ultrafine powder material. 1 fig.

  12. Digital Receiver Phase Meter

    NASA Technical Reports Server (NTRS)

    Marcin, Martin; Abramovici, Alexander

    2008-01-01

    The software of a commercially available digital radio receiver has been modified to make the receiver function as a two-channel low-noise phase meter. This phase meter is a prototype in the continuing development of a phase meter for a system in which radiofrequency (RF) signals in the two channels would be outputs of a spaceborne heterodyne laser interferometer for detecting gravitational waves. The frequencies of the signals could include a common Doppler-shift component of as much as 15 MHz. The phase meter is required to measure the relative phases of the signals in the two channels at a sampling rate of 10 Hz at a root power spectral density <5 microcycle/(Hz)1/2 and to be capable of determining the power spectral density of the phase difference over the frequency range from 1 mHz to 1 Hz. Such a phase meter could also be used on Earth to perform similar measurements in laser metrology of moving bodies. To illustrate part of the principle of operation of the phase meter, the figure includes a simplified block diagram of a basic singlechannel digital receiver. The input RF signal is first fed to the input terminal of an analog-to-digital converter (ADC). To prevent aliasing errors in the ADC, the sampling rate must be at least twice the input signal frequency. The sampling rate of the ADC is governed by a sampling clock, which also drives a digital local oscillator (DLO), which is a direct digital frequency synthesizer. The DLO produces samples of sine and cosine signals at a programmed tuning frequency. The sine and cosine samples are mixed with (that is, multiplied by) the samples from the ADC, then low-pass filtered to obtain in-phase (I) and quadrature (Q) signal components. A digital signal processor (DSP) computes the ratio between the Q and I components, computes the phase of the RF signal (relative to that of the DLO signal) as the arctangent of this ratio, and then averages successive such phase values over a time interval specified by the user.

  13. Direct digital radiography versus conventional radiography – assessment of visibility of file length placed in the root canal: An in vitro study

    PubMed Central

    Ravi, Vaiyapuri; Lipee, Priyadarshini; Rao, Canagapalli Venkat Nakabushan; Lakshmikanthan, Lakshminarayanan

    2012-01-01

    Aim and Objective: To compare conventional and direct digital radiography (DDR) in working length measurement of the root canal and to assess the significance of the different enhancement modes provided by the software to visualize the file length. Materials and Methods: Access cavities were prepared in 30 extracted maxillary central incisors. Size 15 k-file was introduced into the canal till it was flush with the apical foramen. The working length was calculated as 0.5 mm less than the vernier caliper measured length of each file. The files were then sealed with resin at their respective lengths. Intraoral periapical radiographs and direct digital radiographs were taken. Vernier caliper was used to measure the file length in the periapical radiographs, and standard, positive conversion, and colorize modes were used with the CDR system. A multiple regression analysis was conducted to give an accurate analysis between the actual file length and the different groups. Results: There was no statistical significance between the different groups tested. The multiple regression analysis test showed that the positive and colorize modes more accurately corresponded to the actual file length. Conclusion: Both conventional radiography and DDR can be reliably used for working length determination. The positive and colorize modes enhancement features of DDR greatly improve the visual perception, leading to more accurate measurements. PMID:23066272

  14. Capturing Detailed Outcrop Geology Using Terrestrial Laser Scanning (Lidar) and Other Digital Technologies: Current Status and Future Directions

    NASA Astrophysics Data System (ADS)

    Jones, R. R.; McCaffrey, K. J.

    2007-12-01

    Geospatial data acquisition at global to regional scales has wide acceptance, and tools such as Google Earth have been instrumental in extending Earth visualisation far beyond specialist users of GIS and satellite imagery. At the outcrop scale, the number of industry and academic geoscientists adopting digital technologies to gather field data is steadily increasing. When integrated with traditional field skills, these technologies offer two fundamental advantages: firstly, outcrop geology can now be recorded with very high detail and precision; secondly, observations and data are precisely georeferenced, which is a prerequisite for 2D and 3D spatial analysis. Digital outcrop data are being used in a wide variety of ways, many of which can be characterised in terms of two end members. Firstly, using methods such as terrestrial laser scanning and digital photogrammetry, it is possible to create highly realistic virtual copies of the outcrop. These virtual outcrop models can be used to great effect to enhance teaching, to provide virtual field-trips (most effective in conjunction with a real visit to the outcrop), to promote group discussion and interpretation, or as part of Health & Safety briefing. Secondly, digital outcrop data is also being used to derive quantitative attribute measurements from specific geological features. Here the emphasis is not on capturing a photo-realistic copy of the outcrop, but rather on gathering the relevant types of data at the most appropriate resolution and geospatial precision for the type of analysis undertaken. In addition to laser scanning, useful technologies include dGPS, laser range-finding, and Total Station surveying. Examples of this kind of quantitative analysis include fault curvature, roughness, branch-line geometry, spatial variation in fault displacement, fracture spacing and 3D spatial clustering, fold curvature, sedimentary channel morphology, lateral and vertical facies variations, and geomorphological analysis of

  15. Direct Comparison of a Tablet Computer and a Personal Digital Assistant for Point-of-Care Documentation in Eye Care

    PubMed Central

    Silvey, Garry M.; Macri, Jennifer M.; Lee, Paul P.; Lobach, David F.

    2005-01-01

    New mobile computing devices including personal digital assistants (PDAs) and tablet computers have emerged to facilitate data collection at the point of care. Unfortunately, little research has been reported regarding which device is optimal for a given care setting. In this study we created and compared functionally identical applications on a Palm operating system-based PDA and a Windows-based tablet computer for point-of-care documentation of clinical observations by eye care professionals when caring for patients with diabetes. Eye-care professionals compared the devices through focus group sessions and through validated usability surveys. We found that the application on the tablet computer was preferred over the PDA for documenting the complex data related to eye care. Our findings suggest that the selection of a mobile computing platform depends on the amount and complexity of the data to be entered; the tablet computer functions better for high volume, complex data entry, and the PDA, for low volume, simple data entry. PMID:16779128

  16. EnviroAtlas - Average Direct Normal Solar resources kWh/m2/Day by 12-Digit HUC for the Conterminous United States

    EPA Pesticide Factsheets

    The annual average direct normal solar resources by 12-Digit Hydrologic Unit (HUC) was estimated from maps produced by the National Renewable Energy Laboratory for the U.S. Department of Energy (February 2009). The original data was from 10km, satellite modeled dataset (SUNY/NREL, 2007) representing data from 1998-2005. The 10km data was converted to 30m grid cells, and then zonal statistics were estimated for a final value of average kWh/m2/day for each 12-digit HUC. For more information about the original dataset please refer to the National Renewable Energy Laboratory (NREL) website at www.nrel.gov/gis/data_solar.html. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  17. Stereo matching image processing by synthesized color and the characteristic area by the synthesized color

    NASA Astrophysics Data System (ADS)

    Akiyama, Akira; Mutoh, Eiichiro; Kumagai, Hideo

    2014-09-01

    We have developed the stereo matching image processing by synthesized color and the corresponding area by the synthesized color for ranging the object and image recognition. The typical images from a pair of the stereo imagers may have some image disagreement each other due to the size change, missed place, appearance change and deformation of characteristic area. We constructed the synthesized color and corresponding color area with the same synthesized color to make the distinct stereo matching. We constructed the synthesized color and corresponding color area with the same synthesized color by the 3 steps. The first step is making binary edge image by differentiating the focused image from each imager and verifying that differentiated image has normal density of frequency distribution to find the threshold level of binary procedure. We used Daubechies wavelet transformation for the procedures of differentiating in this study. The second step is deriving the synthesized color by averaging color brightness between binary edge points with respect to horizontal direction and vertical direction alternatively. The averaging color procedure was done many times until the fluctuation of averaged color become negligible with respect to 256 levels in brightness. The third step is extracting area with same synthesized color by collecting the pixel of same synthesized color and grouping these pixel points by 4 directional connectivity relations. The matching areas for the stereo matching are determined by using synthesized color areas. The matching point is the center of gravity of each synthesized color area. The parallax between a pair of images is derived by the center of gravity of synthesized color area easily. The experiment of this stereo matching was done for the object of the soccer ball toy. From this experiment we showed that stereo matching by the synthesized color technique are simple and effective.

  18. Direct Visualization of Mucus Production by the Cold-Water Coral Lophelia pertusa with Digital Holographic Microscopy.

    PubMed

    Zetsche, Eva-Maria; Baussant, Thierry; Meysman, Filip J R; van Oevelen, Dick

    2016-01-01

    Lophelia pertusa is the dominant reef-building organism of cold-water coral reefs, and is known to produce significant amounts of mucus, which could involve an important metabolic cost. Mucus is involved in particle removal and feeding processes, yet the triggers and dynamics of mucus production are currently still poorly described because the existing tools to study these processes are not appropriate. Using a novel microscopic technique-digital holographic microscopy (DHM)-we studied the mucus release of L. pertusa under various experimental conditions. DHM technology permits μm-scale observations and allows the visualization of transparent mucoid substances in real time without staining. Fragments of L. pertusa were first maintained in flow-through chambers without stressors and imaged with DHM, then exposed to various stressors (suspended particles, particulate food and air exposure) and re-imaged. Under non-stressed conditions no release of mucus was observed, whilst mucus strings and sheaths were produced in response to suspended particles (activated charcoal and drill cuttings sediment) i.e. in a stressed condition. Mucus strings and so-called 'string balls' were also observed in response to exposure to particulate food (brine shrimp Artemia salina). Upon air-exposure, mucus production was clearly visible once the fragments were returned to the flow chamber. Distinct optical properties such as optical path length difference (OPD) were measured with DHM in response to the various stimuli suggesting that different mucus types are produced by L. pertusa. Mucus produced to reject particles is similar in refractive index to the surrounding seawater, suggesting that the energy content of this mucus is low. In contrast, mucus produced in response to either food particle addition or air exposure had a higher refractive index, suggesting a higher metabolic investment in the production of these mucoid substances. This paper shows for the first time the potential of

  19. Next generation non-vacuum, maskless, low temperature nanoparticle ink laser digital direct metal patterning for a large area flexible electronics.

    PubMed

    Yeo, Junyeob; Hong, Sukjoon; Lee, Daehoo; Hotz, Nico; Lee, Ming-Tsang; Grigoropoulos, Costas P; Ko, Seung Hwan

    2012-01-01

    Flexible electronics opened a new class of future electronics. The foldable, light and durable nature of flexible electronics allows vast flexibility in applications such as display, energy devices and mobile electronics. Even though conventional electronics fabrication methods are well developed for rigid substrates, direct application or slight modification of conventional processes for flexible electronics fabrication cannot work. The future flexible electronics fabrication requires totally new low-temperature process development optimized for flexible substrate and it should be based on new material too. Here we present a simple approach to developing a flexible electronics fabrication without using conventional vacuum deposition and photolithography. We found that direct metal patterning based on laser-induced local melting of metal nanoparticle ink is a promising low-temperature alternative to vacuum deposition- and photolithography-based conventional metal patterning processes. The "digital" nature of the proposed direct metal patterning process removes the need for expensive photomask and allows easy design modification and short turnaround time. This new process can be extremely useful for current small-volume, large-variety manufacturing paradigms. Besides, simple, scalable, fast and low-temperature processes can lead to cost-effective fabrication methods on a large-area polymer substrate. The developed process was successfully applied to demonstrate high-quality Ag patterning (2.1 µΩ·cm) and high-performance flexible organic field effect transistor arrays.

  20. Demonstration of thermal control, microstructure control, defect mitigation and process parameter database generation for Ti-6Al-4V Direct Digital Manufacturing - Understanding defect mitigation and process parameter database generation for direct digital manufacturing

    SciTech Connect

    Dehoff, Ryan R.; Sridharan, Niyanth; Dinwiddie, Ralph; Robson, Alan; Jordan, Brian; Chaudhary, Anil; Babu, Sudarsanam Suresh

    2015-09-01

    Researchers from Manufacturing Demonstration Facility (MDF) at Oak Ridge National Laboratory (ORNL) worked with Applied Optimization (AO) to understand and evaluate the propensity for defect formation in builds manufactured using DM3D-POM laser direct metal deposition. The main aim of this collaboration was to understand the character of powder jet behavior as a function of the nozzle parameters such as cover gas, carrier gas, and shaping gas. In order to evaluate the sensitivities of the parameters used in model, various experiments were performed with in-situ monitoring of the powder stream characteristics using a high speed camera. A wide variety of conditions while keeping the hopper motor rpm constant, including laser power and travel speed were explored. The cross sections of the deposits were characterized using optical microscopy.

  1. PULSE SYNTHESIZING GENERATOR

    DOEpatents

    Kerns, Q.A.

    1963-08-01

    >An electronlc circuit for synthesizing electrical current pulses having very fast rise times includes several sinewave generators tuned to progressively higher harmonic frequencies with signal amplitudes and phases selectable according to the Fourier series of the waveform that is to be synthesized. Phase control is provided by periodically triggering the generators at precisely controlled times. The outputs of the generators are combined in a coaxial transmission line. Any frequency-dependent delays that occur in the transmission line can be readily compensated for so that the desired signal wave shape is obtained at the output of the line. (AEC)

  2. Direct Visualization of Mucus Production by the Cold-Water Coral Lophelia pertusa with Digital Holographic Microscopy

    PubMed Central

    Zetsche, Eva-Maria; Baussant, Thierry; Meysman, Filip J. R.; van Oevelen, Dick

    2016-01-01

    Lophelia pertusa is the dominant reef-building organism of cold-water coral reefs, and is known to produce significant amounts of mucus, which could involve an important metabolic cost. Mucus is involved in particle removal and feeding processes, yet the triggers and dynamics of mucus production are currently still poorly described because the existing tools to study these processes are not appropriate. Using a novel microscopic technique—digital holographic microscopy (DHM)–we studied the mucus release of L. pertusa under various experimental conditions. DHM technology permits μm-scale observations and allows the visualization of transparent mucoid substances in real time without staining. Fragments of L. pertusa were first maintained in flow-through chambers without stressors and imaged with DHM, then exposed to various stressors (suspended particles, particulate food and air exposure) and re-imaged. Under non-stressed conditions no release of mucus was observed, whilst mucus strings and sheaths were produced in response to suspended particles (activated charcoal and drill cuttings sediment) i.e. in a stressed condition. Mucus strings and so-called ‘string balls’ were also observed in response to exposure to particulate food (brine shrimp Artemia salina). Upon air-exposure, mucus production was clearly visible once the fragments were returned to the flow chamber. Distinct optical properties such as optical path length difference (OPD) were measured with DHM in response to the various stimuli suggesting that different mucus types are produced by L. pertusa. Mucus produced to reject particles is similar in refractive index to the surrounding seawater, suggesting that the energy content of this mucus is low. In contrast, mucus produced in response to either food particle addition or air exposure had a higher refractive index, suggesting a higher metabolic investment in the production of these mucoid substances. This paper shows for the first time the

  3. Physiologically driven avian vocal synthesizer

    NASA Astrophysics Data System (ADS)

    Sitt, Jacobo D.; Arneodo, Ezequiel M.; Goller, Franz; Mindlin, Gabriel B.

    2010-03-01

    In this work, we build an electronic syrinx, i.e., a programmable electronic device capable of integrating biomechanical model equations for the avian vocal organ in order to synthesize song. This vocal prosthesis is controlled by the bird’s neural instructions to respiratory and the syringeal motor systems, thus opening great potential for studying motor control and its modification by sensory feedback mechanisms. Furthermore, a well-functioning subject-controlled vocal prosthesis can lay the foundation for similar devices in humans and thus provide directly health-related data and procedures.

  4. Solid phase syntheses of oligoureas

    SciTech Connect

    Burgess, K.; Linthicum, D.S.; Russell, D.H.; Shin, H.; Shitangkoon, A.; Totani, R.; Zhang, A.J.; Ibarzo, J.

    1997-02-19

    Isocyanates 7 were formed from monoprotected diamines 3 or 6, which in turn can be easily prepared from commercially available N-BOC- or N-FMOC-protected amino acid derivatives. Isocyanates 7, formed in situ, could be coupled directly to a solid support functionalized with amine groups or to amino acids anchored on resins using CH{sub 2}Cl{sub 2} as solvent and an 11 h coupling time at 25 {degree}C. Such couplings afforded peptidomimetics with an N-phthaloyl group at the N-terminus. The optimal conditions identified for removal of the N-phthaloyl group were to use 60% hydrazine in DMF for 1-3 h. Several sequences of amino acids coupled to ureas (`peptidic ureas`) and of sequential urea units (`oligoureas`) were prepared via solid phase syntheses and isolated by HPLC. Partition coefficients were measured for two of these peptidomimetics, and their water solubilities were found to be similar to the corresponding peptides. A small library of 160 analogues of the YGGFL-amide sequence was prepared via Houghten`s tea bag methodology. This library was tested for binding to the anti-{beta}-endorphin monoclonal antibody. Overall, this paper describes methodology for solid phase syntheses of oligourea derivatives with side chains corresponding to some of the protein amino acids. The chemistry involved is ideal for high-throughput syntheses and screening operations. 51 refs., 3 figs., 2 tabs.

  5. Metric Aspects of Digital Images and Digital Image Processing.

    DTIC Science & Technology

    1984-09-01

    image files were synthesized aerial images, produced using the program SIM. This program makes use of a digital terrain model containing gray shade...the Arizona test data. This test data was derived from a digitized stereo model formed by two nearly vertical images taken in October 1066 near... digital image processing operations will be investigated in a manner similar to compression. 7) It is hoped that the ability to quantitatively assess

  6. Wisdom, Intelligence & Creativity Synthesized

    ERIC Educational Resources Information Center

    Sternberg, Robert J.

    2009-01-01

    How is it that smart administrators who want to do a good job often find themselves in situations that degenerate into confrontation and, ultimately, termination? In this article, the author discusses why in terms of a model of leadership--which he refers to it as WICS, an acronym for wisdom, intelligence and creativity synthesized. He describes…

  7. Wisdom, Intelligence & Creativity Synthesized

    ERIC Educational Resources Information Center

    Sternberg, Robert J.

    2009-01-01

    How is it that smart administrators who want to do a good job often find themselves in situations that degenerate into confrontation and, ultimately, termination? In this article, the author discusses why in terms of a model of leadership--which he refers to it as WICS, an acronym for wisdom, intelligence and creativity synthesized. He describes…

  8. The Journal Synthesizing Activity.

    ERIC Educational Resources Information Center

    Garber, Zev

    The journal synthesizing activity is intended to combine aspects of the formal essay with that of a diary. Activities associated with lecture topics are written up as short journal entries of approximately five typewritten pages and are turned in during the weekly class session at which the related topic is being discussed. The journal project…

  9. Synthesized night vision goggle

    NASA Astrophysics Data System (ADS)

    Zhou, Haixian

    2000-06-01

    A Synthesized Night Vision Goggle that will be described int his paper is a new type of night vision goggle with multiple functions. It consists of three parts: main observing system, picture--superimposed system (or Cathode Ray Tube system) and Charge-Coupled Device system.

  10. Student-directed investigation of natural phenomena: Using digital simulations to achieve NGSS-aligned 3D learning in middle school

    NASA Astrophysics Data System (ADS)

    Selvans, M. M.; Spafford, C. D.

    2016-12-01

    Many Earth Science phenomena cannot be observed directly because they happen slowly (e.g., Plate Motion) or at large spatial scales (e.g., Weather Patterns). Such topics are investigated by scientists through analysis of large data sets, numerical modeling, and laboratory studies that isolate aspects of the overall phenomena. Middle school students have limited time and lab equipment in comparison, but can employ authentic science practices through investigations using interactive digital simulations (sims). Designing a sim aligned to the Next Generation Science Standards (NGSS) allows students to explore and connect to science ideas in a seamless and supportive way that also deepens their understanding of the phenomena. We helped develop seven units, including the two above, that cover the middle school Earth Science Disciplinary Core Ideas and give students exposure to the other two dimensions of the NGSS (science practices and cross-cutting concepts). These units are developed by the Learning Design Group and Amplify Science. Sims are key to how students engage in 3D learning in these units. For example, in the Rock Transformations Sim students can investigate the ideas that energy from the sun and from Earth's interior can transform rock, and that the transformation processes change the Earth's surface at varying time and spatial scales (ESS2.A). Students can choose and selectively apply transformation processes (melting, weathering, etc.) or energy sources to rock in a cross-section landscape to explore their effects. Students are able to plan steps for making a particular rock transformation happen and carry out their own investigations. A benefit of using a digital platform for student learning is the ability to embed formative assessment. When students plan and carry out missions to achieve specific objectives, the digital platform can capture a record of their actions to measure how they apply science ideas from instruction. Data of these actions, combined

  11. Internal noise of a phase-locked receiver with a loop-controlled synthesizer

    NASA Technical Reports Server (NTRS)

    Greenhall, C. A.

    1979-01-01

    A local oscillator design that uses a digitally programmed frequency synthesizer instead of an analog VCO was proposed. The integral of the synthesizer input, the digital phase, is a convenient measure of integrated Doppler. The internal noise of such a receiver was examined. At high carrier margin, the local oscillator phase noise equals that of the Block IV receiver, about 2 deg rms at S-band, whereas the digital phase noise is about 0.5 deg rms.

  12. Image quality evaluation of direct-conversion digital mammography system with new dual a-Se layer detector

    NASA Astrophysics Data System (ADS)

    Kuwabara, Takao; Iwasaki, Nobuyuki; Sendai, Tomonari; Furue, Ryosuke; Agano, Toshitaka

    2009-02-01

    To increase the detection performance of breast cancers in mammograms, we need to improve shape delineation of micro calcifications and tumors. We accomplished this by developing a direct-conversion mammography system with an optical reading method and a new dual a-Se layer detector. The system achieved both small pixel size (50 micrometer) and a high Detective Quantum Efficiency (DQE) realized by 100 % of fill factor and noise reduction. We evaluated image quality performance and determined the best exposure conditions. We measured DQE and Modulation Transfer Function(MTF) according to the IEC62220-1-2. High DQE was maintained at a low radiation dosage, indicating that the optical reading method accompanies low noises. Response of MTF was maintained at up to the Nyquist frequency of 10 cyc/mm, which corresponds to 50 micrometer pixel size. To determine the best exposure conditions, we measured Contrast to Noise Ratio (CNR) and visually evaluated images of a resected breast under conditions of MoMo, MoRh, and WRh. There were occasional disagreements between the exposure conditions for achieving the maximum CNR and those for the best image graded by the visual evaluation. This was probably because CNR measurement does not measure effects of scattered X-ray. The images verified the improvement in detection and delineation performance of micro calcifications and tumors.

  13. Traveling digital counters for micrometers

    NASA Technical Reports Server (NTRS)

    Haley, C. T.; Moore, J. M.

    1973-01-01

    Five digit micrometer readings are made directly and quickly with no loss of precision. It is virtually impossible for micrometer to be misread. Digitized micrometer can also be used for reptitive measurements.

  14. Digital radiography: an overview.

    PubMed

    Parks, Edwin T; Williamson, Gail F

    2002-11-15

    Since the discovery of X-rays in 1895, film has been the primary medium for capturing, displaying, and storing radiographic images. It is a technology that dental practitioners are the most familiar and comfortable with in terms of technique and interpretation. Digital radiography is the latest advancement in dental imaging and is slowly being adopted by the dental profession. Digital imaging incorporates computer technology in the capture, display, enhancement, and storage of direct radiographic images. Digital imaging offers some distinct advantages over film, but like any emerging technology, it presents new and different challenges for the practitioner to overcome. This article presents an overview of digital imaging including basic terminology and comparisons with film-based imaging. The principles of direct and indirect digital imaging modalities, intraoral and extraoral applications, image processing, and diagnostic efficacy will be discussed. In addition, the article will provide a list of questions dentists should consider prior to purchasing digital imaging systems for their practice.

  15. Digital Direct-to-Consumer Advertising: A Perfect Storm of Rapid Evolution and Stagnant Regulation Comment on "Trouble Spots in Online Direct-to-Consumer Prescription Drug Promotion: A Content Analysis of FDA Warning Letters".

    PubMed

    Mackey, Tim K

    2016-02-03

    The adoption and use of digital forms of direct-to-consumer advertising (also known as "eDTCA") is on the rise. At the same time, the universe of eDTCA is expanding, as technology on Internet-based platforms continues to evolve, from static websites, to social media, and nearly ubiquitous use of mobile devices. However, little is known about how this unique form of pharmaceutical marketing impacts consumer behavior, public health, and overall healthcare utilization. The study by Kim analyzing US Food and Drug Administration (FDA) notices of violations (NOVs) and warning letters regarding online promotional activities takes us in the right direction, but study results raise as many questions as it does answers. Chief among these are unanswered concerns about the unique regulatory challenges posed by the "disruptive" qualities of eDTCA, and whether regulators have sufficient resources and oversight powers to proactively address potential violations. Further, the globalization of eDTCA via borderless Internet-based technologies raises larger concerns about the potential global impact of this form of health marketing unique to only the United States and New Zealand. Collectively, these challenges make it unlikely that regulatory science will be able to keep apace with the continued rapid evolution of eDTCA unless more creative policy solutions are explored.

  16. Visions for a Pan-European digital data infrastructure for groundwater quantity and quality data relevant for implementation of the Water Framework Directive.

    NASA Astrophysics Data System (ADS)

    Hinsby, Klaus; Broers, Hans Peter

    2014-05-01

    The EU Water Framework and Groundwater Directives stipulate that EU member states (MS) should ensure good groundwater chemical and quantitative by 2015. For the assessment of good chemical status the MS have to establish Natural Background Levels (NBLs) and Threshold Values (TVs) for groundwater bodies at risk and compare current concentration levels to these. In addition the MS shall ensure trend reversals in cases where contaminants or water levels show critical increasing or decreasing trends. The EU MS have to demonstrate that the quantitative and chemical status of its groundwater bodies does not put drinking water, ecosystems or other legitimate uses at risk. Easy on-line access to relevant visualizations of groundwater quality and quantity data of e.g. nitrate, chloride, arsenic and water tables in Europe's major aquifer types compiled from national databases would be of great importance for managers, authorities and scientists conducting risk and status assessments. The Water Resources Expert Group of the EuroGeoSurveys propose to develop Pan-European interactive on-line digital maps and visualizations of concentrations levels and trends, as well as calculated natural background levels and threshold values for the most important aquifer types of Europe mainly derived based on principles established in the former EU project "BRIDGE" - Background cRiteria for the IDentification of Groundwater Thresholds. Further, we propose to develop Pan-European digital and dynamic maps and cross sections in close collaboration with ecologists, which delineate dependent or associated terrestrial and aquatic ecosystems across Europe where groundwater quantity and quality plays a significant role in sustaining good ecological status of the ecosystem, and where the water resources and ecosystems are most vulnerable to climate change. Finally, integrated water resources management requires integrated consideration of both deep and shallow groundwater and surface water issues

  17. Explaining Synthesized Software

    NASA Technical Reports Server (NTRS)

    VanBaalen, Jeffrey; Robinson, Peter; Lowry, Michael; Pressburger, Thomas; Lau, Sonie (Technical Monitor)

    1998-01-01

    Motivated by NASA's need for high-assurance software, NASA Ames' Amphion project has developed a generic program generation system based on deductive synthesis. Amphion has a number of advantages, such as the ability to develop a new synthesis system simply by writing a declarative domain theory. However, as a practical matter, the validation of the domain theory for such a system is problematic because the link between generated programs and the domain theory is complex. As a result, when generated programs do not behave as expected, it is difficult to isolate the cause, whether it be an incorrect problem specification or an error in the domain theory. This paper describes a tool we are developing that provides formal traceability between specifications and generated code for deductive synthesis systems. It is based on extensive instrumentation of the refutation-based theorem prover used to synthesize programs. It takes augmented proof structures and abstracts them to provide explanations of the relation between a specification, a domain theory, and synthesized code. In generating these explanations, the tool exploits the structure of Amphion domain theories, so the end user is not confronted with the intricacies of raw proof traces. This tool is crucial for the validation of domain theories as well as being important in everyday use of the code synthesis system. It plays an important role in validation because when generated programs exhibit incorrect behavior, it provides the links that can be traced to identify errors in specifications or domain theory. It plays an important role in the everyday use of the synthesis system by explaining to users what parts of a specification or of the domain theory contribute to what pieces of a generated program. Comments are inserted into the synthesized code that document these explanations.

  18. Synthesizing folded band chaos

    NASA Astrophysics Data System (ADS)

    Corron, Ned J.; Hayes, Scott T.; Pethel, Shawn D.; Blakely, Jonathan N.

    2007-04-01

    A randomly driven linear filter that synthesizes Lorenz-like, reverse-time chaos is shown also to produce Rössler-like folded band wave forms when driven using a different encoding of the random source. The relationship between the topological entropy of the random source, dissipation in the linear filter, and the positive Lyapunov exponent for the reverse-time wave form is exposed. The two drive encodings are viewed as grammar restrictions on a more general encoding that produces a chaotic superset encompassing both the Lorenz butterfly and Rössler folded band paradigms of nonlinear dynamics.

  19. Validating NASA's Airborne Multikilohertz Microlaser Altimeter (Microaltimeter) by Direct Comparison of Data Taken Over Ocean City, Maryland Against an Existing Digital Elevation Model

    NASA Technical Reports Server (NTRS)

    Abel, Peter

    2003-01-01

    NASA's Airborne Multikilohertz Microlaser Altimeter (Microaltimeter) is a scanning, photon-counting laser altimeter, which uses a low energy (less than 10 microJuoles), high repetition rate (approximately 10 kHz) laser, transmitting at 532 nm. A 14 cm diameter telescope images the ground return onto a segmented anode photomultiplier, which provides up to 16 range returns for each fire. Multiple engineering flights were made during 2001 and 2002 over the Maryland and Virginia coastal area, all during daylight hours. Post-processing of the data to geolocate the laser footprint and determine the terrain height requires post- detection Poisson filtering techniques to extract the actual ground returns from the noise. Validation of the instrument's ability to produce accurate terrain heights will be accomplished by direct comparison of data taken over Ocean City, Maryland with a Digital Elevation Model (DEM) of the region produced at Ohio State University (OSU) from other laser altimeter and photographic sources. The techniques employed to produce terrain heights from the Microaltimeter ranges will be shown, along with some preliminary comparisons with the OSU DEM.

  20. Using digital image processing to characterize the Campbell-Stokes sunshine recorder and to derive high-temporal resolution direct solar irradiance

    NASA Astrophysics Data System (ADS)

    Sanchez-Romero, A.; González, J. A.; Calbó, J.; Sanchez-Lorenzo, A.

    2014-09-01

    The Campbell-Stokes sunshine recorder (CSSR) has been one of the most commonly used instruments for measuring sunshine duration (SD) through the burn length of a given CSSR card. Many authors have used SD to obtain information about cloudiness and solar radiation (by using Ångström-Prescott type formulas). Contrarily, the burn width has not been used systematically. In principle, the burn width increases for increasing direct beam irradiance. The aim of this research is to show the relationship between burn width and direct solar irradiance (DSI), and to prove whether this relationship depends on the type of CSSR and burning card. A semi-automatic method based on image processing of digital scanned images of burnt cards is presented. With this method, the temporal evolution of the burn width with 1 min resolution can be obtained. From this, SD is easily calculated and compared with the traditional (i.e. visual) determination. The method tends to slightly overestimate SD but the thresholds that are used in the image processing could be adjusted to obtain an unbiased estimation. Regarding the burn width, results show that there is a high correlation between two different models of CSSRs, as well as a strong relationship between burn widths and DSI at a high-temporal resolution. Thus, for example, hourly DSI may be estimated from the burn width with higher accuracy than based on burn length (for one of the CSSR, relative root mean squared error 24 and 30% respectively; mean bias error -0.6 and -30.0 W m-2 respectively). The method offers a practical way to exploit long-term sets of CSSR cards to create long time series of DSI. Since DSI is affected by atmospheric aerosol content, CSSR records may also become a proxy measurement for turbidity and atmospheric aerosol loading.

  1. Using digital image processing to characterize the Campbell-Stokes sunshine recorder and to derive high-temporal resolution direct solar irradiance

    NASA Astrophysics Data System (ADS)

    Sanchez-Romero, A.; González, J. A.; Calbó, J.; Sanchez-Lorenzo, A.

    2015-01-01

    The Campbell-Stokes sunshine recorder (CSSR) has been one of the most commonly used instruments for measuring sunshine duration (SD) through the burn length of a given CSSR card. Many authors have used SD to obtain information about cloudiness and solar radiation (by using Ångström-Prescott type formulas), but the burn width has not been used systematically. In principle, the burn width increases for increasing direct beam irradiance. The aim of this research is to show the relationship between burn width and direct solar irradiance (DSI) and to prove whether this relationship depends on the type of CSSR and burning card. A method of analysis based on image processing of digital scanned images of burned cards is used. With this method, the temporal evolution of the burn width with 1 min resolution can be obtained. From this, SD is easily calculated and compared with the traditional (i.e., visual) determination. The method tends to slightly overestimate SD, but the thresholds that are used in the image processing could be adjusted to obtain an improved estimation. Regarding the burn width, experimental results show that there is a high correlation between two different models of CSSRs, as well as a strong relationship between burn widths and DSI at a high-temporal resolution. Thus, for example, hourly DSI may be estimated from the burn width with higher accuracy than based on burn length (for one of the CSSR, relative root mean squared error is 24 and 30%, respectively; mean bias error is -0.6 and -30.0 W m-2, respectively). The method offers a practical way to exploit long-term sets of CSSR cards to create long time series of DSI. Since DSI is affected by atmospheric aerosol content, CSSR records may also become a proxy measurement for turbidity and atmospheric aerosol loading.

  2. Anthropometric precision and accuracy of digital three-dimensional photogrammetry: comparing the Genex and 3dMD imaging systems with one another and with direct anthropometry.

    PubMed

    Weinberg, Seth M; Naidoo, Sybill; Govier, Daniel P; Martin, Rick A; Kane, Alex A; Marazita, Mary L

    2006-05-01

    A variety of commercially available three-dimensional (3D) surface imaging systems are currently in use by craniofacial specialists. Little is known, however, about how measurement data generated from alternative 3D systems compare, specifically in terms of accuracy and precision. The purpose of this study was to compare anthropometric measurements obtained by way of two different digital 3D photogrammetry systems (Genex and 3dMD) as well as direct anthropometry and to evaluate intraobserver precision across these three methods. On a sample of 18 mannequin heads, 12 linear distances were measured twice by each method. A two-factor repeated measures analysis of variance was used to test simultaneously for mean differences in precision across methods. Additional descriptive statistics (e.g., technical error of measurement [TEM]) were used to quantify measurement error magnitude. Statistically significant (P < 0.05) mean differences were observed across methods for nine anthropometric variables; however, the magnitude of these differences was consistently at the submillimeter level. No significant differences were noted for precision. Moreover, the magnitude of imprecision was determined to be very small, with TEM scores well under 1 mm, and intraclass correlation coefficients ranging from 0.98 to 1. Results indicate that overall mean differences across these three methods were small enough to be of little practical importance. In terms of intraobserver precision, all methods fared equally well. This study is the first attempt to simultaneously compare 3D surface imaging systems directly with one another and with traditional anthropometry. Results suggest that craniofacial surface data obtained by way of alternative 3D photogrammetric systems can be combined or compared statistically.

  3. Information retrieval for ecological syntheses.

    PubMed

    Bayliss, Helen R; Beyer, Fiona R

    2015-06-01

    Research syntheses are increasingly being conducted within the fields of ecology and environmental management. Information retrieval is crucial in any synthesis in identifying data for inclusion whilst potentially reducing biases in the dataset gathered, yet the nature of ecological information provides several challenges when compared with medicine that should be considered when planning and undertaking searches. We present ten recommendations for anyone considering undertaking information retrieval for ecological research syntheses that highlight the main differences with medicine and, if adopted, may help reduce biases in the dataset retrieved, increase search efficiency and improve reporting standards. They are as follows: (1) plan for information retrieval at an early stage, (2) identify and use sources of help, (3) clearly define the question to be addressed, (4) ensure that provisions for managing, recording and reporting the search are in place, (5) select an appropriate search type, (6) identify sources to be used, (7) identify limitations of the sources, (8) ensure that the search vocabulary is appropriate, (9) identify limits and filters that can help direct the search, and (10) test the strategy to ensure that it is realistic and manageable. These recommendations may be of value for other disciplines where search infrastructures are not yet sufficiently well developed. Copyright © 2014 John Wiley & Sons, Ltd.

  4. SYNTH: A spectrum synthesizer

    NASA Astrophysics Data System (ADS)

    Hensley, W. K.; McKinnon, A. D.; Miley, H. S.; Panisko, M. E.; Savard, R. M.

    1993-10-01

    A computer code has been written at the Pacific Northwest Laboratory (PNL) to synthesize the results of typical gamma ray spectroscopy experiments. The code, dubbed SYNTH, allows a user to specify physical characteristics of a gamma ray source, the quantity of the nuclides producing the radiation, the source-to-detector distance and the presence of absorbers, the type and size of the detector, and the electronic set up used to gather the data. In the process of specifying the parameters needed to synthesize a spectrum, several interesting intermediate results are produced, including a photopeak transmission function versus energy, a detector efficiency curve, and a weighted list of gamma and x rays produced from a set of nuclides. All of these intermediate results are available for graphical inspection and for printing. SYNTH runs on personal computers. It is menu driven and can be customized to user specifications. SYNTH contains robust support for coaxial germanium detectors and some support for sodium iodide detectors. SYNTH is not a finished product. A number of additional developments are planned. However, the existing code has been compared carefully to spectra obtained from National Institute for Standards and Technology (NIST) certified standards with very favorable results. Examples of the use of SYNTH and several spectral results are presented.

  5. Direct Digital Modulation Converter (DDMC)

    DTIC Science & Technology

    1976-01-01

    nftre gnal chure sol sance geuse line nade bette mic rite doi bour fac d^ne gote boc vane vise tare lire pelle cage vute...dose teur z6re tal cure nol zance pi re relle gage vute jante donde bore boule lien vieux tui pose gueur mfire mal gnure sol ...rague rate rame touse touche toupe toure toube toute toude toufe toune tougue toure toufe vire vide vine vigne vique vife vice vile vive vime vigne

  6. Digital Libraries.

    ERIC Educational Resources Information Center

    Fox, Edward A.; Urs, Shalini R.

    2002-01-01

    Provides an overview of digital libraries research, practice, and literature. Highlights include new technologies; redefining roles; historical background; trends; creating digital content, including conversion; metadata; organizing digital resources; services; access; information retrieval; searching; natural language processing; visualization;…

  7. Digital Libraries.

    ERIC Educational Resources Information Center

    Fox, Edward A.; Urs, Shalini R.

    2002-01-01

    Provides an overview of digital libraries research, practice, and literature. Highlights include new technologies; redefining roles; historical background; trends; creating digital content, including conversion; metadata; organizing digital resources; services; access; information retrieval; searching; natural language processing; visualization;…

  8. Design and implementation of a multiband digital filter using FPGA to extract the ECG signal in the presence of different interference signals.

    PubMed

    Aboutabikh, Kamal; Aboukerdah, Nader

    2015-07-01

    In this paper, we propose a practical way to synthesize and filter an ECG signal in the presence of four types of interference signals: (1) those arising from power networks with a fundamental frequency of 50Hz, (2) those arising from respiration, having a frequency range from 0.05 to 0.5Hz, (3) muscle signals with a frequency of 25Hz, and (4) white noise present within the ECG signal band. This was done by implementing a multiband digital filter (seven bands) of type FIR Multiband Least Squares using a digital programmable device (Cyclone II EP2C70F896C6 FPGA, Altera), which was placed on an education and development board (DE2-70, Terasic). This filter was designed using the VHDL language in the Quartus II 9.1 design environment. The proposed method depends on Direct Digital Frequency Synthesizers (DDFS) designed to synthesize the ECG signal and various interference signals. So that the synthetic ECG specifications would be closer to actual ECG signals after filtering, we designed in a single multiband digital filter instead of using three separate digital filters LPF, HPF, BSF. Thus all interference signals were removed with a single digital filter. The multiband digital filter results were studied using a digital oscilloscope to characterize input and output signals in the presence of differing sinusoidal interference signals and white noise.

  9. Keeping Dublin Core Simple: Cross-Domain Discovery or Resource Description?; First Steps in an Information Commerce Economy: Digital Rights Management in the Emerging E-Book Environment; Interoperability: Digital Rights Management and the Emerging EBook Environment; Searching the Deep Web: Direct Query Engine Applications at the Department of Energy.

    ERIC Educational Resources Information Center

    Lagoze, Carl; Neylon, Eamonn; Mooney, Stephen; Warnick, Walter L.; Scott, R. L.; Spence, Karen J.; Johnson, Lorrie A.; Allen, Valerie S.; Lederman, Abe

    2001-01-01

    Includes four articles that discuss Dublin Core metadata, digital rights management and electronic books, including interoperability; and directed query engines, a type of search engine designed to access resources on the deep Web that is being used at the Department of Energy. (LRW)

  10. Keeping Dublin Core Simple: Cross-Domain Discovery or Resource Description?; First Steps in an Information Commerce Economy: Digital Rights Management in the Emerging E-Book Environment; Interoperability: Digital Rights Management and the Emerging EBook Environment; Searching the Deep Web: Direct Query Engine Applications at the Department of Energy.

    ERIC Educational Resources Information Center

    Lagoze, Carl; Neylon, Eamonn; Mooney, Stephen; Warnick, Walter L.; Scott, R. L.; Spence, Karen J.; Johnson, Lorrie A.; Allen, Valerie S.; Lederman, Abe

    2001-01-01

    Includes four articles that discuss Dublin Core metadata, digital rights management and electronic books, including interoperability; and directed query engines, a type of search engine designed to access resources on the deep Web that is being used at the Department of Energy. (LRW)

  11. Implantable digital hearing aid

    NASA Technical Reports Server (NTRS)

    Kissiah, A. M., Jr.

    1979-01-01

    Hearing aid converts analog output of microphone into digital pulses in about 10 channels of audiofrequencies. Each pulse band could be directly connected to portion of auditory nerve most sensitive to that range.

  12. Strategies for Building Digitized Collections. Strategies and Tools for the Digital Library.

    ERIC Educational Resources Information Center

    Smith, Abby

    In April 2000, the Digital Library Federation commissioned three reports to address broader concerns about digital collections in research libraries. This report synthesizes the nearly 10 years' experience that libraries have had digitizing items from their rare, special, and general collections, and making them available online. The report…

  13. Method for synthesizing HMX

    DOEpatents

    McGuire, Raymond R.; Coon, Clifford L.; Harrar, Jackson E.; Pearson, Richard K.

    1984-01-01

    A method and apparatus for electrochemically synthesizing N.sub.2 O.sub.5 cludes oxidizing a solution of N.sub.2 O.sub.4 /HNO.sub.3 at an anode, while maintaining a controlled potential between the N.sub.2 O.sub.4 /HNO.sub.3 solution and the anode. A potential of about 1.35 to 2.0 V vs. SCE is preferred, while a potential of about 1.80 V vs. SCE is most preferred. Thereafter, the N.sub.2 O.sub.5 is reacted with either 1.5-diacetyl-3,7-dinitro-1,3,5,7-tetraazacyclooctane (DADN) or 1,3,5,7-tetraacetyl-1,3,5,7-tetraazacyclooctane (TAT) to form cyclotetramethylenetetraamine (HMX).

  14. Synthesized light transients.

    PubMed

    Wirth, A; Hassan, M Th; Grguras, I; Gagnon, J; Moulet, A; Luu, T T; Pabst, S; Santra, R; Alahmed, Z A; Azzeer, A M; Yakovlev, V S; Pervak, V; Krausz, F; Goulielmakis, E

    2011-10-14

    Manipulation of electron dynamics calls for electromagnetic forces that can be confined to and controlled over sub-femtosecond time intervals. Tailored transients of light fields can provide these forces. We report on the generation of subcycle field transients spanning the infrared, visible, and ultraviolet frequency regimes with a 1.5-octave three-channel optical field synthesizer and their attosecond sampling. To demonstrate applicability, we field-ionized krypton atoms within a single wave crest and launched a valence-shell electron wavepacket with a well-defined initial phase. Half-cycle field excitation and attosecond probing revealed fine details of atomic-scale electron motion, such as the instantaneous rate of tunneling, the initial charge distribution of a valence-shell wavepacket, the attosecond dynamic shift (instantaneous ac Stark shift) of its energy levels, and its few-femtosecond coherent oscillations.

  15. Digital synchronization and communication techniques

    NASA Technical Reports Server (NTRS)

    Lindsey, William C.

    1992-01-01

    Information on digital synchronization and communication techniques is given in viewgraph form. Topics covered include phase shift keying, modems, characteristics of open loop digital synchronizers, an open loop phase and frequency estimator, and a digital receiver structure using an open loop estimator in a decision directed architecture.

  16. Acquisition hardware for digital imaging.

    PubMed

    Widmer, William R

    2008-01-01

    Use of digital radiography is growing rapidly in veterinary medicine. Two basic digital imaging systems are available, computed radiography (CR) and direct digital radiography (DDR). Computed radiographic detectors use a two-step process for image capture and processing. Image capture is by X-ray sensitive phosphors in the image plate. The image plate reader transforms the latent phosphor image to light photons that are converted to an analog electrical signal. An analog to digital converter is used to digitize the electrical signal before computer analysis. Direct digital detectors provide digital data by direct readout after image capture--a reader unnecessary. Types of DDR detectors are flat panel detectors and charge coupled device (CCD) detectors. Flat panel detectors are composed of layers of semiconductors for image capture with transistor and microscopic circuitry embedded in a pixel array. Direct converting flat panel detectors convert incident X-rays directly into electrical charges. Indirect detectors convert X-rays to visible light, then to electrical charges. All flat panel detectors send a digitized electrical signal to a computer using a direct link. Charge coupled device detectors have a small chip similar to those used in digital cameras. A scintillator first converts X-rays to a light signal that is minified by an optical system before reaching the chip. The chip sends a digital signal directly to a computer. Both CR and DDR provide quality diagnostic images. CR is a mature technology while DDR is an emerging technology.

  17. Characterization of the Campbell-Stokes sunshine duration recorder and its ability to derive direct solar radiation by using digital image processing

    NASA Astrophysics Data System (ADS)

    Sanchez-Romero, Alejandro; González, Josep-Abel; Calbó, Josep; Sanchez-Lorenzo, Arturo

    2014-05-01

    The World Meteorological Organization defines the sunshine duration (SD) as the time that, along a given period, direct solar irradiance (DSI) exceeds the threshold level of 120 W/m2. Since the end of 19th century, the Campbell-Stokes sunshine recorder (CSSR) has been the most commonly used instrument used for measuring SD. Due to the large number of long records that exist worldwide, valuable climatic information can be extracted from them. Many authors have used the daily SD (as obtained from the measurement of the length of burn for a given card) to obtain additional information about solar radiation, by using Ångström-Prescott type formulas. Contrarily, the burn width has not been systematically used. Theoretically, the burn is wider (narrower) when the direct insolation is stronger (weaker). The aim of this research is to show the relationship between burn width and DSI, and to prove whether this relationship depends on the type of CSSR and burning card. The research has been carried out in Girona (NE Spain) for a period of two years (from January 2012 to January 2014). Two different models of CSSR (which use different types of cards) and a pyrheliometer from Kipp&Zonen were used to measure SD and DSI, respectively. A semi-automatic method based on image processing of digital scanned images of burnt cards is presented. The method can be summarized in four steps: (i) scan each band on a green background; (ii) apply a digital process to increase the contrast of the burn; (iii) define two/three points in the image, depending of the geometry of the card, to point the center of the day (12.00 TST) on the image and define the trajectory of the sun with 1-minute intervals; and (iv) apply a program to make cross-sections every minute and measure the width of burn. So, after all of this process, we obtain a temporal evolution of the burn width with 1-minute resolution and distinguishing between morning and afternoon. The results show that there is a good correlation

  18. Sensitivity of a direct computer-aided detection system in full-field digital mammography for detection of microcalcifications not associated with mass or architectural distortion.

    PubMed

    Scaranelo, Anabel M; Crystal, Pavel; Bukhanov, Karina; Helbich, Thomas H

    2010-06-01

    The purpose of this study was to evaluate the sensitivity of a direct computer-aided detection (CAD) system (d-CAD) in full-field digital mammography (FFDM) for the detection of microcalcifications not associated with mass or architectural distortion. A database search of 1063 consecutive stereotactic core biopsies performed between 2002 and 2005 identified 196 patients with Breast Imaging-Reporting and Data System (BI-RADS) 4 and 5 microcalcifications not associated with mass or distortion detected exclusively by bilateral FFDM. A commercially available CAD system (Second Look, version 7.2) was retrospectively applied to the craniocaudal and mediolateral oblique views in these patients (mean age, 59 years; range, 35-84 years). Breast density, location and mammographic size of the lesion, distribution, and tumour histology were recorded and analysed by using chi(2), Fisher exact, or McNemar tests, when applicable. When using d-CAD, 71 of 74 malignant microcalcification cases (96%) and 101 of 122 benign microcalcifications (83%) were identified. There was a significant difference (P < .05) between CAD sensitivity on the craniocaudal view, 91% (68 of 75), vs CAD sensitivity on the mediolateral oblique view, 80% (60 of 75). The d-CAD sensitivity for dense breast tissue (American College of Radiology [ACR] density 3 and 4) was higher (97%) than d-CAD sensitivity (95%) for nondense tissue (ACR density 1 and 2), but the difference was not statically significant. All 28 malignant calcifications larger than 10 mm were detected by CAD, whereas the sensitivity for lesions small than or equal to 10 mm was 94%. D-CAD had a high sensitivity in the depiction of asymptomatic breast cancers, which were seen as microcalcifications on FFDM screening, with a sensitivity of d-CAD on the craniocaudal view being significantly better. All malignant microcalcifications larger than 10 mm were detected by d-CAD. Copyright 2010 Canadian Association of Radiologists. Published by Elsevier Inc

  19. EUS-guided portal pressure measurement using a digital pressure wire with real-time remote display: a novel, minimally invasive technique for direct measurement in an animal model.

    PubMed

    Schulman, Allison R; Thompson, Christopher C; Ryou, Marvin

    2016-04-01

    Hepatic venous pressure gradient (HVPG) currently serves as a surrogate for portal pressure measurement but has many limitations. We developed a novel technique for rapid and direct portal pressure measurements using a digital pressure wire delivered through an EUS-guided 22-gauge FNA needle. Our aims were to evaluate (1) the short-term safety and technical feasibility, (2) procedural duration and subjective workload assessment, and (3) accuracy compared with a transjugular criterion standard approach. The subjects were Yorkshire pigs, weighing 40 to 55 kg. The portal vein was identified by using a linear array echoendoscope and accessed with a commercially available 22-gauge FNA needle preloaded with a digital pressure wire. Access was confirmed by portal venography. Mean digital pressure measurements were recorded over 30 to 60 seconds, and the National Aeronautics and Space Administration Task Load Index was scored. The control measurements were conventional transjugular catheterization with a balloon occlusion catheter to obtain free and wedged hepatic pressures, with subsequent HVPG calculation. The total time required for EUS identification and needle access of the portal vein, venography, and digital pressure measurement was less than 5 minutes in 5 of 5 pigs. The National Aeronautics and Space Administration Task Load Index scores revealed a low subjective workload. Baseline portal pressure measurements via EUS ranged from 5 mm Hg to 10 mm Hg (mean, 6.4 mm Hg). HVPG measurements were consistently ±1 mm Hg of portal pressure. This study is the first report of direct EUS-guided portal pressure measurements by using a digital pressure wire. This method is routinely performed in minutes and provides real-time pressure tracings via wireless transmission. This novel approach for direct portal pressure measurement has the potential to replace traditional indirect HVPG measurements. Copyright © 2016 American Society for Gastrointestinal Endoscopy. Published by

  20. Digital Preservation.

    ERIC Educational Resources Information Center

    Yakel, Elizabeth

    2001-01-01

    Reviews research on digital preservation issues, including born-digital and digitally recreated documents. Discusses electronic records research; metadata and other standards; electronic mail; Web-based documents; moving images media; selection of materials for digitization, including primary sources; administrative issues; media stability…

  1. Doclet To Synthesize UML

    NASA Technical Reports Server (NTRS)

    Barry, Matthew R.; Osborne, Richard N.

    2005-01-01

    The RoseDoclet computer program extends the capability of Java doclet software to automatically synthesize Unified Modeling Language (UML) content from Java language source code. [Doclets are Java-language programs that use the doclet application programming interface (API) to specify the content and format of the output of Javadoc. Javadoc is a program, originally designed to generate API documentation from Java source code, now also useful as an extensible engine for processing Java source code.] RoseDoclet takes advantage of Javadoc comments and tags already in the source code to produce a UML model of that code. RoseDoclet applies the doclet API to create a doclet passed to Javadoc. The Javadoc engine applies the doclet to the source code, emitting the output format specified by the doclet. RoseDoclet emits a Rose model file and populates it with fully documented packages, classes, methods, variables, and class diagrams identified in the source code. The way in which UML models are generated can be controlled by use of new Javadoc comment tags that RoseDoclet provides. The advantage of using RoseDoclet is that Javadoc documentation becomes leveraged for two purposes: documenting the as-built API and keeping the design documentation up to date.

  2. Pre-ozonation coupled with UV/H2O2 process for the decolorization and mineralization of cotton dyeing effluent and synthesized C.I. Direct Black 22 wastewater.

    PubMed

    Shu, Hung-Yee; Chang, Ming-Chin

    2005-05-20

    The decolorization and mineralization of cotton dyeing effluent containing C.I. Acid Black 22 as well as synthesized C.I. Acid Black 22 wastewater by means of advanced oxidation processes (AOPs), such as UV/H2O2, O3 and pre-ozonation coupled with UV/H2O2 processes, were evaluated in this study. It was observed that the UV/H2O2 process took longer retention time than ozonation for color removal of dye bath effluent. Reversely, the total organic carbon (TOC) removal showed different phenomena that ozonation and UV/H2O2 process obtained 33 and 90% of removal efficiency for 160 min of retention time, respectively. Additionally, laboratory synthesized dye wastewater was substantially more efficient in the decolorization process than dye bath effluent. Therefore, in this work, pre-ozonation coupled with UV/H2O2 process was employed to enhance the reduction of both color and TOC in dye bath effluent at the same time. At the same time, the retention time demand was reduced to less than 115 min for 90% removal of TOC and color by this combined process.

  3. Digital rotation measurement unit

    DOEpatents

    Sanderson, S.N.

    1983-09-30

    A digital rotation indicator is disclosed for monitoring the position of a valve member having a movable actuator. The indicator utilizes mercury switches adapted to move in cooperation with the actuator. Each of the switches produces an output as it changes state when the actuator moves. A direction detection circuit is connected to the switches to produce a first digital signal indicative of the direction of rotation of the actuator. A count pulse generating circuit is also connected to the switches to produce a second digital pulse signal having count pulses corresponding to a change of state of any of the mercury switches. A reset pulse generating circuit is provided to generate a reset pulse each time a count pulse is generated. An up/down counter is connected to receive the first digital pulse signal and the second digital pulse signal and to count the pulses of the second digital pulse signal either up or down depending upon the instantaneous digital value of the first digital signal whereby a running count indicative of the movement of the actuator is maintained.

  4. Digital Sensor Technology

    SciTech Connect

    Thomas, Ken D.; Quinn, Edward L.; Mauck, Jerry L.; Bockhorst, Richard M.

    2015-02-01

    The nuclear industry has been slow to incorporate digital sensor technology into nuclear plant designs due to concerns with digital qualification issues. However, the benefits of digital sensor technology for nuclear plant instrumentation are substantial in terms of accuracy and reliability. This paper, which refers to a final report issued in 2013, demonstrates these benefits in direct comparisons of digital and analog sensor applications. Improved accuracy results from the superior operating characteristics of digital sensors. These include improvements in sensor accuracy and drift and other related parameters which reduce total loop uncertainty and thereby increase safety and operating margins. An example instrument loop uncertainty calculation for a pressure sensor application is presented to illustrate these improvements. This is a side-by-side comparison of the instrument loop uncertainty for both an analog and a digital sensor in the same pressure measurement application. Similarly, improved sensor reliability is illustrated with a sample calculation for determining the probability of failure on demand, an industry standard reliability measure. This looks at equivalent analog and digital temperature sensors to draw the comparison. The results confirm substantial reliability improvement with the digital sensor, due in large part to ability to continuously monitor the health of a digital sensor such that problems can be immediately identified and corrected. This greatly reduces the likelihood of a latent failure condition of the sensor at the time of a design basis event. Notwithstanding the benefits of digital sensors, there are certain qualification issues that are inherent with digital technology and these are described in the report. One major qualification impediment for digital sensor implementation is software common cause failure (SCCF).

  5. Ohmic Contacts for Technology for Frequency Agile Digitally Synthesized Transmitters

    DTIC Science & Technology

    2010-07-01

    Au (50/100 nm) ohmic contacts sput - tered onto p-type InGaAs were either ohmic or non-ohmic depending on the conditions used to create the plasma...yielded linear I-V curves (an ohmic con- tact]. It is important to note here that a lower working pressure during sput - tering leads to a longer mean...needed to complete the thesis. Eric worked on pre-metallization surface preparation, as well as plated and sput - tered contacts. Robert Dormaier 111

  6. Super-resolution digital holographic microscopy using multi-point light sources illumination

    NASA Astrophysics Data System (ADS)

    Phan, Anh-Hoang; Park, Jae-Hyeung; Kim, Nam; Jeon, Seok-Hee

    2010-02-01

    In this paper, we use multi-point source illumination to enhance the resolution of digital holographic microscopy without shifting the CCD camera. The specimen is illuminated from many directions by using multi-point sources which are easily created by a lens-array. The high frequency information of the specimen can be captured at a fixed position of CCD camera. All information is then synthesized to increase the resolution.

  7. Digital imaging.

    PubMed

    Daniel, Gregory B

    2009-07-01

    Medical imaging is rapidly moving toward a digital-based image system. An understanding of the principles of digital imaging is necessary to evaluate features of imaging systems and can play an important role in purchasing decisions.

  8. Digital Booktalk: Digital Media for Reluctant Readers

    ERIC Educational Resources Information Center

    Gunter, Glenda; Kenny, Robert

    2008-01-01

    New learning and communications paradigms of today's learners are extending the definition of literacy and directly affecting how reading and writing skills are acquired (Leu, 2000). Mirroring an ever-expanding definition of literacy, new college and K-12 curricular programs that redefine digital media are popping up all over the country. Story is…

  9. Digital Booktalk: Digital Media for Reluctant Readers

    ERIC Educational Resources Information Center

    Gunter, Glenda; Kenny, Robert

    2008-01-01

    New learning and communications paradigms of today's learners are extending the definition of literacy and directly affecting how reading and writing skills are acquired (Leu, 2000). Mirroring an ever-expanding definition of literacy, new college and K-12 curricular programs that redefine digital media are popping up all over the country. Story is…

  10. Doppler extraction with a digital VCO

    NASA Technical Reports Server (NTRS)

    Starner, E. R.; Nossen, E. J.

    1977-01-01

    Digitally controlled oscillator in phased-locked loop may be useful for data communications systems, or may be modified to serve as information extraction component of microwave or optical system for collision avoidance or automatic braking. Instrument is frequency-synthesizing device with output specified precisely by digital number programmed into frequency register.

  11. Method for synthesizing ultrafine powder materials

    DOEpatents

    Buss, Richard J.; Ho, Pauline

    1988-01-01

    A method for synthesizing ultrafine powder materials, for example, ceramic and metal powders, comprises admitting gaseous reactants from which the powder material is to be formed into a vacuum reaction chamber maintained at a pressure less than atmospheric and at a temperature less than about 400.degree. K. (127.degree.C.). The gaseous reactants are directed through a glow discharge provided in the vacuum reaction chamber to form the ultrafine powder material.

  12. Digital Imaging.

    ERIC Educational Resources Information Center

    Howell, Les

    1996-01-01

    Defines a digital photograph as a numerical record of light electronically measured and recorded by a computer's scanner. States that most personal computers cannot do digital photography successfully and that digital pictures can be hard to manage and present a storage problem. Finds that, once the school has the hardware/software, picture…

  13. Digital Imaging.

    ERIC Educational Resources Information Center

    Howell, Les

    1996-01-01

    Defines a digital photograph as a numerical record of light electronically measured and recorded by a computer's scanner. States that most personal computers cannot do digital photography successfully and that digital pictures can be hard to manage and present a storage problem. Finds that, once the school has the hardware/software, picture…

  14. Digital Citizenship

    ERIC Educational Resources Information Center

    Isman, Aytekin; Canan Gungoren, Ozlem

    2014-01-01

    Era in which we live is known and referred as digital age.In this age technology is rapidly changed and developed. In light of these technological advances in 21st century, schools have the responsibility of training "digital citizen" as well as a good citizen. Digital citizens must have extensive skills, knowledge, Internet and …

  15. The quantum vector digital voltmeter of INMETRO

    NASA Astrophysics Data System (ADS)

    Kuerten Ihlenfeld, Waldemar G.; Landim, Regis P.

    2016-07-01

    The paper describes the quantum vector digital voltmeter developed at INMETRO, which is based on a programmable Josephson voltage synthesizer. The system employs digital regulation for phase-alignment and frequency synchronization of signals, is fully automated and allows calibration of ac sources and analog-to-digital converters with uncertainties bearing some parts of 10-07 up to frequencies of around 500 Hz.

  16. A MULTICHANNEL DIGITAL DATA ACQUISITION SYSTEM,

    DTIC Science & Technology

    A digital data acquisition system (DIDAS) is discussed with emphasis on its concepts and capabilities. Any arbitrary combination of 43 inputs made...up of 36 analog inputs, 6 digital inputs, and 1 events pulse input may be sampled at rates up to 6000 samples per second, digitized where necessary...and recorded on magnetic tape. These output digital tapes are suitable for direct entry into an IBM 7090 or similar digital computer. Since the

  17. Digital Natives or Digital Tribes?

    ERIC Educational Resources Information Center

    Watson, Ian Robert

    2013-01-01

    This research builds upon the discourse surrounding digital natives. A literature review into the digital native phenomena was undertaken and found that researchers are beginning to identify the digital native as not one cohesive group but of individuals influenced by other factors. Primary research by means of questionnaire survey of technologies…

  18. Improved assays for DNA-polymerizing enzymes by the use of enzymatically synthesized 5-( sup 125 I)iodo-2'-deoxyuridine triphosphate, illustrated by direct quantitation of anti-HIV reverse transcriptase antibody and by serum DNA polymerase analyses

    SciTech Connect

    Neumueller, M.K.; Karlstroem, A.R.K.; Kaellander, C.F.G.; Gronowitz, J.S. )

    1990-02-01

    A one-step procedure which uses enzymes in a crude extract of herpes simplex virus (HSV) type 1-infected cells to synthesize 5-(125I)iodo-2'-deoxyuridine triphosphate (( 125I)dUTP) from (125I)dU is described. The design of a one-step procedure for the purification of the product is also presented. The recovery of (125I)dUTP from (125I)dU varied between 50 and 75%, the radiochemical purity of the product was greater than 90%, and both synthesis and purification were completed within 8 h. The sensitivity and specificity of (125I)dUTP as a substrate for both DNA-dependent DNA polymerase (DNAp) and RNA-dependent DNA polymerase (reverse transcriptase, RT) were evaluated and compared to those of (3H)dTTP for the following specimens: purified cloned Klenow fragment, crude extracts of HeLa-, BHK-, and HSV-2-infected BHK cells, purified avian myeloblastosis virus RT, and purified cloned human immunodeficiency virus (HIV) RT. The (125I)dUTP was accepted as a substrate equally as well (3H)dTTP by all of the specimens at all of the concentrations tested. When the same amount of radiolabel was used, (125I)dUTP gave a sensitivity 10- to 25-fold higher than that of (3H)dTTP. The gain in sensitivity was due to the higher specific activity and a higher counting efficiency of the 125I-label compound. The use of (125I)dUTP also offered technical advantages over alternative substrates available, such as product separation without acid precipitation and exclusion of the need for scintillation cocktails. The half-life of the nucleic also gives a reasonable shelf-life for use in routine assays. Activity of less than 0.3 pg of HIV RT could be detected when the new substrate was used, and this made it possible to quantitate HIV RT antibodies (abs) in diluted serum samples without purifying the immunoglobulin.

  19. Digital subtraction angiography of the heart and lungs

    SciTech Connect

    Moodie, D.S.; Yiannikas, J.

    1986-01-01

    This book contains 12 chapters. Some of the chapter titles are: Physical Principles of Cardiac Digital Subtraction Angiography, The Use of Intravenous Digital Subtraction Angiography in Evaluating Patients with Complex Congenital Heart Disease, Exercise Intravenous Digital Subtraction Angiograpny, Cardiomyopathic and Cardiac Neoplastic Disease, Digital Subtraction Angiography in the Catheterization Laboratory, and Cardiac Digital Subtraction Angiography - Future Directions.

  20. Application of QC_DR software for acceptance testing and routine quality control of direct digital radiography systems: initial experiences using the Italian Association of Physicist in Medicine quality control protocol.

    PubMed

    Nitrosi, Andrea; Bertolini, Marco; Borasi, Giovanni; Botti, Andrea; Barani, Adriana; Rivetti, Stefano; Pierotti, Luisa

    2009-12-01

    Ideally, medical x-ray imaging systems should be designed to deliver maximum image quality at an acceptable radiation risk to the patient. Quality assurance procedures are employed to ensure that these standards are maintained. A quality control protocol for direct digital radiography (DDR) systems is described and discussed. Software to automatically process and analyze the required images was developed. In this paper, the initial results obtained on equipment of different DDR manufacturers were reported. The protocol was developed to highlight even small discrepancies in standard operating performance.

  1. Biofunctionalization and capping of template synthesized nanotubes.

    PubMed

    Hillebrenner, Heather; Buyukserin, Fatih; Stewart, Jon D; Martin, Charles R

    2007-07-01

    Using alumina templates both nanotubes (open on both ends) and nano test tubes (open on only one end) have been synthesized from many different materials and these have great potential as delivery vehicles for biomedical applications. This review focuses on our recent results directed towards developing "smart" nanotubes for biomolecule delivery applications. While intensive efforts have focused on spherical nanoparticles that are easier to make, cylindrical particles or nanotubes offer many advantages. First, the tunable alumina template allows one to dictate both the pore diameter and length of the nanotube. In addition, template synthesized nanotubes can be differentially functionalized on their inner and outer surfaces. This review highlights these advantages in the contexts of drug extraction and antibody-antigen interactions, the synthesis of protein nanotubes, and recent advances in covalently capped ("corked") nanotubes designed to prevent premature payload leakage. Though diverse applications for nanotubes have already been discovered, many new and exciting paths await exploration.

  2. Digit ratio in birds.

    PubMed

    Lombardo, Michael P; Thorpe, Patrick A; Brown, Barbara M; Sian, Katie

    2008-12-01

    The Homeobox (Hox) genes direct the development of tetrapod digits. The expression of Hox genes may be influenced by endogenous sex steroids during development. Manning (Digit ratio. New Brunswick, NJ: Rutgers University Press, 2002) predicted that the ratio between the lengths of digits 2 (2D) and 4 (4D) should be sexually dimorphic because prenatal exposure to estrogens and androgens positively influence the lengths of 2D and 4D, respectively. We measured digits and other morphological traits of birds from three orders (Passeriformes, house sparrow, Passer domesticus; tree swallow, Tachycineta bicolor; Pscittaciformes, budgerigar, Melopsittacus undulates; Galliformes, chicken, Gallus domesticus) to test this prediction. None were sexually dimorphic for 2D:4D and there were no associations between 2D:4D and other sexually dimorphic traits. When we pooled data from all four species after we averaged right and left side digits from each individual and z-transformed the resulting digit ratios, we found that males had significantly larger 2D:4D than did females. Tetrapods appear to be sexually dimorphic for 2D:4D with 2D:4D larger in males as in some birds and reptiles and 2D:4D smaller in males as in some mammals. The differences between the reptile and mammal lineages in the directionality of 2D:4D may be related to the differences between them in chromosomal sex determination. We suggest that (a) natural selection for a perching foot in the first birds may have overridden the effects of hormones on the development of digit ratio in this group of vertebrates and (b) caution be used in making inferences about prenatal exposure to hormones and digit ratio in birds.

  3. Digital Imaging

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Digital Imaging is the computer processed numerical representation of physical images. Enhancement of images results in easier interpretation. Quantitative digital image analysis by Perceptive Scientific Instruments, locates objects within an image and measures them to extract quantitative information. Applications are CAT scanners, radiography, microscopy in medicine as well as various industrial and manufacturing uses. The PSICOM 327 performs all digital image analysis functions. It is based on Jet Propulsion Laboratory technology, is accurate and cost efficient.

  4. Synthesizing genetic sequential logic circuit with clock pulse generator.

    PubMed

    Chuang, Chia-Hua; Lin, Chun-Liang

    2014-05-28

    Rhythmic clock widely occurs in biological systems which controls several aspects of cell physiology. For the different cell types, it is supplied with various rhythmic frequencies. How to synthesize a specific clock signal is a preliminary but a necessary step to further development of a biological computer in the future. This paper presents a genetic sequential logic circuit with a clock pulse generator based on a synthesized genetic oscillator, which generates a consecutive clock signal whose frequency is an inverse integer multiple to that of the genetic oscillator. An analogous electronic waveform-shaping circuit is constructed by a series of genetic buffers to shape logic high/low levels of an oscillation input in a basic sinusoidal cycle and generate a pulse-width-modulated (PWM) output with various duty cycles. By controlling the threshold level of the genetic buffer, a genetic clock pulse signal with its frequency consistent to the genetic oscillator is synthesized. A synchronous genetic counter circuit based on the topology of the digital sequential logic circuit is triggered by the clock pulse to synthesize the clock signal with an inverse multiple frequency to the genetic oscillator. The function acts like a frequency divider in electronic circuits which plays a key role in the sequential logic circuit with specific operational frequency. A cascaded genetic logic circuit generating clock pulse signals is proposed. Based on analogous implement of digital sequential logic circuits, genetic sequential logic circuits can be constructed by the proposed approach to generate various clock signals from an oscillation signal.

  5. Digital Discrimination

    ERIC Educational Resources Information Center

    Blansett, Jim

    2008-01-01

    In recent years, the Internet has become a digital commons of commerce and education. However, accessibility standards have often been overlooked online, and the digital equivalents to curb-cuts and other physical accommodations have only rarely been implemented to serve those with print disabilities. (A print disability can be a learning…

  6. Digitizing Preservation.

    ERIC Educational Resources Information Center

    Conway, Paul

    1994-01-01

    Discussion of digital imaging technology focuses on its potential use for preservation of library materials. Topics addressed include converting microfilm to digital; the high cost of conversion from paper or microfilm; quality; indexing; database management issues; incompatibility among imaging systems; longevity; cooperative pilot projects; and…

  7. Digital Discrimination

    ERIC Educational Resources Information Center

    Blansett, Jim

    2008-01-01

    In recent years, the Internet has become a digital commons of commerce and education. However, accessibility standards have often been overlooked online, and the digital equivalents to curb-cuts and other physical accommodations have only rarely been implemented to serve those with print disabilities. (A print disability can be a learning…

  8. Digital TMI

    NASA Technical Reports Server (NTRS)

    Rios, Joseph

    2012-01-01

    Presenting the current status of the Digital TMI project to visiting members of the FAA Command Center. Digital TMI is an effort to store national-level traffic management initiatives in a standards-compliant manner. Work is funded by the FAA.

  9. Digital Roundup

    ERIC Educational Resources Information Center

    Horn, Michael B.

    2013-01-01

    State policy is crucial to the spread of digital-learning opportunities at the elementary and secondary level. A review of recent legislative action reveals policies that are constantly in flux and differ quite markedly from one state to another. Some have hoped for model digital-learning legislation that could handle all the various issues…

  10. Reactanceless synthesized impedance bandpass amplifier

    NASA Technical Reports Server (NTRS)

    Kleinberg, L. L. (Inventor)

    1985-01-01

    An active R bandpass filter network is formed by four operational amplifier stages interconnected by discrete resistances. One pair of stages synthesize an equivalent input impedance of an inductance (L sub eq) in parallel with a discrete resistance (R sub o) while the second pair of stages synthesizes an equivalent input impedance of a capacitance (C sub eq) serially coupled to another discrete resistance (R sub i) coupled in parallel with the first two stages. The equivalent input impedances aggregately define a tuned resonant bandpass filter in the roll-off regions of the operational amplifiers.

  11. Effectiveness of Digital Pulse Processing Using a Slow Waveform Digitizer

    NASA Astrophysics Data System (ADS)

    Anthony, Adam; Ahmed, Mohammad; Sikora, Mark

    2016-09-01

    Using a waveform digitizer, one can replace nearly all of the analog electronics typically involved in processing pulses from a detector by directly digitizing the signal and processing it using digital algorithms. Algorithms for timing filter amplification, constant fraction discrimination, trapezoidal pulse shaping, peak sensing with pileup rejection, and charge integration were developed and implemented. The algorithms and a digitizer with a sampling rate of 62.5 MS/sec were used to calculate the energy and timing resolution of a various scintillation and solid state detectors. These resolutions are compared against both a traditional charge to digital (QDC), and the analog to digital (ADC) data acquisition setup in use at the High Intensity Gamma Source at Duke University. Preliminary results are presented.

  12. Digital Frequency Domain Multiplexer for mm-Wavelength Telescopes

    SciTech Connect

    Spieler, Helmuth G; Dobbs, Matt; Bissonnette, Eric; Spieler, Helmuth G.

    2007-07-23

    An FPGA based digital signal processing (DSP) system for biasing and reading out multiplexed bolometric detectors for mm-wavelength telescopes is presented. This readout system is being deployed for balloon-borne and ground based cosmology experiments with the primary goal of measuring the signature of inflation with the Cosmic Microwave Background Radiation. The system consists of analog superconducting electronics running at 250 mK and 4 K, coupled to digital room temperature backend electronics described here. The digital electronics perform the real time functionality with DSP algorithms implemented in firmware. A soft embedded processor provides all of the slow housekeeping control and communications. Each board in the system synthesizes multi-frequency combs of 8 to 32 carriers in the MHz band to bias the detectors. After the carriers have been modulated with the sky-signal by the detectors, the same boards digitize the comb directly. The carriers are mixed down to base-band and low pass filtered. The signal bandwidth of 0.050Hz-100 Hz places extreme requirements on stability and requires powerful filtering techniques to recover the sky-signal from the MHz carriers.

  13. Information Retrieval for Ecological Syntheses

    ERIC Educational Resources Information Center

    Bayliss, Helen R.; Beyer, Fiona R.

    2015-01-01

    Research syntheses are increasingly being conducted within the fields of ecology and environmental management. Information retrieval is crucial in any synthesis in identifying data for inclusion whilst potentially reducing biases in the dataset gathered, yet the nature of ecological information provides several challenges when compared with…

  14. Method of synthesizing pyrite nanocrystals

    DOEpatents

    Wadia, Cyrus; Wu, Yue

    2013-04-23

    A method of synthesizing pyrite nanocrystals is disclosed which in one embodiment includes forming a solution of iron (III) diethyl dithiophosphate and tetra-alkyl-ammonium halide in water. The solution is heated under pressure. Pyrite nanocrystal particles are then recovered from the solution.

  15. Laboratory Syntheses of Insect Pheromones.

    ERIC Educational Resources Information Center

    Cormier, Russell A.; Hoban, James N.

    1984-01-01

    Provides background information and procedures for the multi-step synthesis of tiger moth and boll weevil pheromones (sex attractants). These syntheses require several laboratory periods. The tiger moth pheromone synthesis is suitable for introductory organic chemistry while the boll weevil pheromone is recommended for an advanced laboratory…

  16. Information Retrieval for Ecological Syntheses

    ERIC Educational Resources Information Center

    Bayliss, Helen R.; Beyer, Fiona R.

    2015-01-01

    Research syntheses are increasingly being conducted within the fields of ecology and environmental management. Information retrieval is crucial in any synthesis in identifying data for inclusion whilst potentially reducing biases in the dataset gathered, yet the nature of ecological information provides several challenges when compared with…

  17. Laboratory Syntheses of Insect Pheromones.

    ERIC Educational Resources Information Center

    Cormier, Russell A.; Hoban, James N.

    1984-01-01

    Provides background information and procedures for the multi-step synthesis of tiger moth and boll weevil pheromones (sex attractants). These syntheses require several laboratory periods. The tiger moth pheromone synthesis is suitable for introductory organic chemistry while the boll weevil pheromone is recommended for an advanced laboratory…

  18. Digital Ethics/Going Digital.

    ERIC Educational Resources Information Center

    Wilson, Bradley

    1996-01-01

    Finds that the recent National Press Photographers Association code of ethics can serve as a model for any photography staff. Discusses how digital imaging is becoming commonplace in classrooms, due to decreasing costs and easier software. Explains digital terminology. Concludes that time saved in the darkroom and at the printer is now spent on…

  19. Digital Ethics/Going Digital.

    ERIC Educational Resources Information Center

    Wilson, Bradley

    1996-01-01

    Finds that the recent National Press Photographers Association code of ethics can serve as a model for any photography staff. Discusses how digital imaging is becoming commonplace in classrooms, due to decreasing costs and easier software. Explains digital terminology. Concludes that time saved in the darkroom and at the printer is now spent on…

  20. Magnetic digital microfluidics - a review.

    PubMed

    Zhang, Yi; Nguyen, Nam-Trung

    2017-03-14

    A digital microfluidic platform manipulates droplets on an open surface. Magnetic digital microfluidics utilizes magnetic forces for actuation and offers unique advantages compared to other digital microfluidic platforms. First, the magnetic particles used in magnetic digital microfluidics have multiple functions. In addition to serving as actuators, they also provide a functional solid substrate for molecule binding, which enables a wide range of applications in molecular diagnostics and immunodiagnostics. Second, magnetic digital microfluidics can be manually operated in a "power-free" manner, which allows for operation in low-resource environments for point-of-care diagnostics where even batteries are considered a luxury item. This review covers research areas related to magnetic digital microfluidics. This paper first summarizes the current development of magnetic digital microfluidics. Various methods of droplet manipulation using magnetic forces are discussed, ranging from conventional magnetic particle-based actuation to the recent development of ferrofluids and magnetic liquid marbles. This paper also discusses several new approaches that use magnetically controlled flexible substrates for droplet manipulation. In addition, we emphasize applications of magnetic digital microfluidics in biosensing and medical diagnostics, and identify the current limitations of magnetic digital microfluidics. We provide a perspective on possible solutions to close these gaps. Finally, the paper discusses the future improvement of magnetic digital microfluidics to explore potential new research directions.

  1. Impact of 50% Synthesized Iso-Paraffins (SIP) on F-76 Fuel Coalescence

    DTIC Science & Technology

    2013-12-16

    petroleum JP-5 and Synthesized Iso-Paraffins (SIP). SIP fuels are made from direct fermentation of sugar into olefinic hydrocarbons. The olefinic...5 and Synthesized Iso-Paraffins (SIP). SIP fuels are made from direct fermentation of sugar into olefinic hydrocarbons. The olefinic hydrocarbons...of petroleum JP-5 and Synthesized Iso- Paraffins (SIP). SIP fuels are made from direct fermentation of sugar into olefinic hydrocarbons. The olefinic

  2. Digital circuits for computer applications: A compilation

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The innovations in this updated series of compilations dealing with electronic technology represent a carefully selected collection of digital circuits which have direct application in computer oriented systems. In general, the circuits have been selected as representative items of each section and have been included on their merits of having universal applications in digital computers and digital data processing systems. As such, they should have wide appeal to the professional engineer and scientist who encounter the fundamentals of digital techniques in their daily activities. The circuits are grouped as digital logic circuits, analog to digital converters, and counters and shift registers.

  3. Digital Workload In A Large Radiology Department

    NASA Astrophysics Data System (ADS)

    Goodsitt, Mitchell M.; Bauman, Roger A.; Lodwick, Gwilym S.

    1986-06-01

    As Radiology becomes more invested in direct digital imaging techniques, the potential for moving these images throughout the department, interpreting them directly in digital mode and archiving them in computer form is a topic of high current interest. A fundamental consideration is the amount of digital data to be handled. Even the low and medium resolution images now handled in digital mode require immense amounts of digital storage space. The first quantification of the amount of digital data was by Dwyer, et al, in a report concerning the workload in a 614-bed hospital. Their assumptions and calculations are reviewed and applied to the workload data from a 1082-bed hospital. Storage requirements for PET and MRI workload are calculated, and an estimate of digital radiography data is presented. The digitization of plain film radiographs will virtually increase the storage requirements by a factor of 10.

  4. Energy Efficient Digital Networks

    SciTech Connect

    Lanzisera, Steven; Brown, Richard

    2013-01-01

    Digital networks are the foundation of the information services, and play an expanding and indispensable role in our lives, via the Internet, email, mobile phones, etc. However, these networks consume energy, both through the direct energy use of the network interfaces and equipment that comprise the network, and in the effect they have on the operating patterns of devices connected to the network. The purpose of this research was to investigate a variety of technology and policy issues related to the energy use caused by digital networks, and to further develop several energy-efficiency technologies targeted at networks.

  5. A comparison of the precision of three-dimensional images acquired by 2 digital intraoral scanners: effects of tooth irregularity and scanning direction

    PubMed Central

    Anh, Ji-won; Park, Ji-Man; Chun, Youn-Sic; Kim, Miae

    2016-01-01

    Objective The purpose of this study was to compare the precision of three-dimensional (3D) images acquired using iTero® (Align Technology Inc., San Jose, CA, USA) and Trios® (3Shape Dental Systems, Copenhagen, Denmark) digital intraoral scanners, and to evaluate the effects of the severity of tooth irregularities and scanning sequence on precision. Methods Dental arch models were fabricated with differing degrees of tooth irregularity and divided into 2 groups based on scanning sequence. To assess their precision, images were superimposed and an optimized superimposition algorithm was employed to measure any 3D deviation. The t-test, paired t-test, and one-way ANOVA were performed (p < 0.05) for statistical analysis. Results The iTero® and Trios® systems showed no statistically significant difference in precision among models with differing degrees of tooth irregularity. However, there were statistically significant differences in the precision of the 2 scanners when the starting points of scanning were different. The iTero® scanner (mean deviation, 29.84 ± 12.08 µm) proved to be less precise than the Trios® scanner (22.17 ± 4.47 µm). Conclusions The precision of 3D images differed according to the degree of tooth irregularity, scanning sequence, and scanner type. However, from a clinical standpoint, both scanners were highly accurate regardless of the degree of tooth irregularity. PMID:26877977

  6. Digital Epidemiology

    PubMed Central

    Salathé, Marcel; Bengtsson, Linus; Bodnar, Todd J.; Brewer, Devon D.; Brownstein, John S.; Buckee, Caroline; Campbell, Ellsworth M.; Cattuto, Ciro; Khandelwal, Shashank; Mabry, Patricia L.; Vespignani, Alessandro

    2012-01-01

    Mobile, social, real-time: the ongoing revolution in the way people communicate has given rise to a new kind of epidemiology. Digital data sources, when harnessed appropriately, can provide local and timely information about disease and health dynamics in populations around the world. The rapid, unprecedented increase in the availability of relevant data from various digital sources creates considerable technical and computational challenges. PMID:22844241

  7. Reconfigurable intensity modulation and direct detection optical transceivers for variable-rate wavelength-division-multiplexing passive optical networks utilizing digital signal processing-based symbol mapper

    NASA Astrophysics Data System (ADS)

    Zhang, Zhiguo; Zhang, Bingbing; Chen, Yanxu; Chen, Xue

    2017-01-01

    Variable-rate intensity modulation and direct detection-based optical transceivers with software-controllable reconfigurability and transmission performance adaptability are experimentally demonstrated, utilizing M-QAM symbol mapping implemented in MATLAB® programs. A frequency division multiplexing-based symbol demapping and wavelength management method is proposed for the symbol demapper and tunable laser management used in colorless optical network unit.

  8. Digital radiography.

    PubMed

    Mattoon, J S

    2006-01-01

    Digital radiography has been used in human medical imaging since the 1980s with recent and rapid acceptance into the veterinary profession. Using advanced image capture and computer technology, radiographic images are viewed on a computer monitor. This is advantageous because radiographic images can be adjusted using dedicated computer software to maximize diagnostic image quality. Digital images can be accessed at computer workstations throughout the hospital, instantly retrieved from computer archives, and transmitted via the internet for consultation or case referral. Digital radiographic data can also be incorporated into a hospital information system, making record keeping an entirely paperless process. Digital image acquisition is faster when compared to conventional screen-film radiography, improving workflow and patient throughput. Digital radiography greatly reduces the need for 'retake' radiographs because of wide latitude in exposure factors. Also eliminated are costs associated with radiographic film and x-ray film development. Computed radiography, charged coupled devices, and flat panel detectors are types of digital radiography systems currently available.

  9. Digital video.

    PubMed

    Johnson, Don; Johnson, Mike

    2004-04-01

    The process of digital capture, editing, and archiving video has become an important aspect of documenting arthroscopic surgery. Recording the arthroscopic findings before and after surgery is an essential part of the patient's medical record. The hardware and software has become more reasonable to purchase, but the learning curve to master the software is steep. Digital video is captured at the time of arthroscopy to a hard disk, and written to a CD at the end of the operative procedure. The process of obtaining video of open procedures is more complex. Outside video of the procedure is recorded on digital tape with a digital video camera. The camera must be plugged into a computer to capture the video on the hard disk. Adobe Premiere software is used to edit the video and render the finished video to the hard drive. This finished video is burned onto a CD. We outline the choice of computer hardware and software for the manipulation of digital video. The techniques of backup and archiving the completed projects and files also are outlined. The uses of digital video for education and the formats that can be used in PowerPoint presentations are discussed.

  10. Determinism in synthesized chaotic waveforms.

    PubMed

    Corron, Ned J; Blakely, Jonathan N; Hayes, Scott T; Pethel, Shawn D

    2008-03-01

    The output of a linear filter driven by a randomly polarized square wave, when viewed backward in time, is shown to exhibit determinism at all times when embedded in a three-dimensional state space. Combined with previous results establishing exponential divergence equivalent to a positive Lyapunov exponent, this result rigorously shows that such reverse-time synthesized waveforms appear equally to have been produced by a deterministic chaotic system.

  11. Catalytic method for synthesizing hydrocarbons

    DOEpatents

    Sapienza, R.S.; Sansone, M.J.; Slegeir, W.A.R.

    A method for synthesizing hydrocarbons from carbon monoxide and hydrogen by contacting said gases with a slurry of a catalyst composed of palladium or platinum and cobalt supported on a solid phase is disclosed. The catalyst is prepared by heating a heterogeneous component of the palladium or platinum deposited on the solid support in a solution of cobalt carbonyl or precursors thereof. The catalyst exhibits excellent activity, stability in air, and produces highly desirable product fractions even with dilute gaseous reactants.

  12. Catalytic method for synthesizing hydrocarbons

    DOEpatents

    Sapienza, Richard S.; Sansone, Michael J.; Slegeir, William A. R.

    1984-01-01

    A method for synthesizing hydrocarbons from carbon monoxide and hydrogen by contacting said gases with a slurry of a catalyst composed of palladium or platinum and cobalt supported on a solid phase is disclosed. The catalyst is prepared by heating a heterogeneous component of the palladium or platinum deposited on the solid support in a solution of cobalt carbonyl or precursors thereof. The catalyst exhibits excellent activity, stability in air, and produces highly desirable product fractions even with dilute gaseous reactants.

  13. TSS-Thermal Synthesizer System

    NASA Technical Reports Server (NTRS)

    Chimenti, Edward; Rickman, Steven; Vogt, Robert; Longo, Carlos R. Ortiz; Bauman, Noel; Lepore, Joseph; Mackey, Phil; Pavlovsky, James, II; Welch, Mark; Fogerson, Peter; Dawber, Mark; Fong, Cynthia Jone; Hecke, Peter; Morrison, Susan; Castillo, Ernie; Chou, ZU; Fried, Lawrence; Howard, Jerry; Lombardi, Mike; Middleton, Jack

    1996-01-01

    Thermal Synthesizer System (TSS) is integrated set of thermal-analysis application programs designed to solve problems encountered by thermal engineers. Combines functionality of Systems Improved Numerical Differencing Analyzer/Fluid Integrator (SINDA/FLUINT) and radiation analysis with friendly and easily understood user-interface environment coupled with powerful interactive color graphics and geometric modeling capability. Enables thermal engineers to spend more time solving engineering problems instead of laboriously constructing and verifying math models. Written in FORTRAN and C language.

  14. TSS-Thermal Synthesizer System

    NASA Technical Reports Server (NTRS)

    Chimenti, Edward; Rickman, Steven; Vogt, Robert; Longo, Carlos R. Ortiz; Bauman, Noel; Lepore, Joseph; Mackey, Phil; Pavlovsky, James, II; Welch, Mark; Fogerson, Peter; hide

    1996-01-01

    Thermal Synthesizer System (TSS) is integrated set of thermal-analysis application programs designed to solve problems encountered by thermal engineers. Combines functionality of Systems Improved Numerical Differencing Analyzer/Fluid Integrator (SINDA/FLUINT) and radiation analysis with friendly and easily understood user-interface environment coupled with powerful interactive color graphics and geometric modeling capability. Enables thermal engineers to spend more time solving engineering problems instead of laboriously constructing and verifying math models. Written in FORTRAN and C language.

  15. Digital magnetic temperature transducer.

    NASA Technical Reports Server (NTRS)

    Tchernev, D. I.; Collier, T. E.

    1971-01-01

    A new digital magnetic temperature transducer is reported. The device utilizes the discontinuous behavior of the initial permeability with temperature at the Curie temperature of some magnetic materials. Since the Curie temperature is determined by the chemical and crystallographic composition of the particular material only, the transducer requires no calibration and has extremely high stability and reproducibility with time. The output of the transducer is inherently digital and, therefore, is directly compatible with the digital information processing and control without A/D conversion. The temperature-sensing portion of the transducer consists only of magnetic cores and wire and, therefore, has extremely high reliability, is shock and radiation insensitive, small, and virtually indestructible.

  16. Digital magnetic temperature transducer.

    NASA Technical Reports Server (NTRS)

    Tchernev, D. I.; Collier, T. E.

    1971-01-01

    A new digital magnetic temperature transducer is reported. The device utilizes the discontinuous behavior of the initial permeability with temperature at the Curie temperature of some magnetic materials. Since the Curie temperature is determined by the chemical and crystallographic composition of the particular material only, the transducer requires no calibration and has extremely high stability and reproducibility with time. The output of the transducer is inherently digital and, therefore, is directly compatible with the digital information processing and control without A/D conversion. The temperature-sensing portion of the transducer consists only of magnetic cores and wire and, therefore, has extremely high reliability, is shock and radiation insensitive, small, and virtually indestructible.

  17. Digital Collections, Digital Libraries & the Digitization of Cultural Heritage Information.

    ERIC Educational Resources Information Center

    Lynch, Clifford

    2002-01-01

    Discusses digital collections and digital libraries. Topics include broadband availability; digital rights protection; content, both non-profit and commercial; digitization of cultural content; sustainability; metadata harvesting protocol; infrastructure; authorship; linking multiple resources; data mining; digitization of reference works;…

  18. A direct current superconducting quantum interference device gradiometer with a digital signal processor controlled flux-locked loop and comparison with a conventional analog feedback scheme

    SciTech Connect

    Kung, P.J.; Bracht, R.R.; Flynn, E.R.; Lewis, P.S.

    1996-01-01

    A double-washer dc superconducting quantum interference device (SQUID) gradiometer with a flux-locked loop (FLL) based on a digital signal processor (DSP) has been developed for biomagnetic applications. All of the analog electronics in the conventional FLL are replaced and implemented by the DSP except for the low-noise field-effect transistor preamplifier at the front end of the signal recovery components. The DSP performs the signal demodulation by synchronously sampling the recovered signals and applying the appropriate full wave rectification. The signals are then integrated, filtered, and applied to the output. At 4.2 K, the white flux noise of the gradiometer measured in a DSP FLL mode is about 4{mu}{phi}{sub 0}/{radical}Hz and the noise at 1 Hz is 13 {mu}{phi}{sub 0}/{radical}Hz. The corresponding noise levels in the gradiometer operated by the conventional FLL are 1.8 and 3{mu}{phi}{sub 0}/{radical}Hz. The poorer system performance in the DSP FLL compared to the analog FLL is mainly caused by the ambient field noise and interference signals picked up through the connecting cables. Additional noise is also added to the overall noise floor by the instruments employed in the DSP system in the present prototype setup. Further improvement in the noise characteristics and the dynamic behavior of the DSP SQUID gradiometer is expected when a better configuration of DSP with the associated I/O devices is implemented. Additional improvements of the DSP programs are expected by incorporating higher-order integration, adaptive control, and noise reduction schemes. {copyright} {ital 1996 American Institute of Physics.}

  19. Synthesized speech intelligibility among native speakers and non-native speakers of English.

    PubMed

    Alamsaputra, Diane Mayasari; Kohnert, Kathryn J; Munson, Benjamin; Reichle, Joe

    2006-12-01

    Using synthesized and digitized speech in electronic communication devices may greatly benefit individuals who cannot produce intelligible speech. However, multiple investigations have demonstrated that synthesized speech is not always sufficiently intelligible for its listeners. Listening to synthesized speech may be particularly problematic for listeners for whom English is a second language. We compared native and non-native English-speaking adults' listening accuracy for English sentences in natural voice and synthesized voice conditions. Results indicated a disproportionate disadvantage for the non-native English-speaking group when listening to synthesized speech compared to their native English-speaking age peers. There was, however, significant variability in performance within the non-native English group, and this was strongly related to independent measures of English language skill. Specifically, a large portion of the variance in performance on the synthesized speech task was predicted by participants' receptive vocabulary scores.

  20. Digital signal processing control of induction machine`s torque and stator flux utilizing the direct stator flux field orientation method

    SciTech Connect

    Seiz, Julie Burger

    1997-04-01

    This paper presents a review of the Direct Stator Flux Field Orientation control method. This method can be used to control an induction motor`s torque and flux directly and is the application of interest for this thesis. This control method is implemented without the traditional feedback loops and associated hardware. Predictions are made, by mathematical calculations, of the stator voltage vector. The voltage vector is determined twice a switching period. The switching period is fixed throughout the analysis. The three phase inverter duty cycle necessary to control the torque and flux of the induction machine is determined by the voltage space vector Pulse Width Modulation (PWM) technique. Transient performance of either the flux or torque requires an alternate modulation scheme which is also addressed in this thesis. A block diagram of this closed loop system is provided. 22 figs., 7 tabs.

  1. Digital imaging in dentistry.

    PubMed

    Essen, S Donovan

    2011-01-01

    Information technology is vital to operations, marketing, accounting, finance and administration. One of the most exciting and quickly evolving technologies in the modern dental office is digital applications. The dentist is often the business manager, information technology officer and strategic planning chief for his small business. The information systems triangle applies directly to this critical manager supported by properly trained ancillary staff and good equipment. With emerging technology driving all medical disciplines and the rapid pace at which it emerges, it is vital for the contemporary practitioner to keep abreast of the newest information technology developments. This article compares the strategic and operational advantages of digital applications, specifically imaging. The focus of this paper will be on digital radiography (DR), 3D computerized tomography, digital photography and digitally-driven CAD/CAM to what are now considered obsolescing modalities and contemplates what may arrive in the future. It is the purpose of this essay to succinctly evaluate the decisions involved in the role, application and implications of employing this tool in the dental environment

  2. Next Generation Non-Vacuum, Maskless, Low Temperature Nanoparticle Ink Laser Digital Direct Metal Patterning for a Large Area Flexible Electronics

    PubMed Central

    Yeo, Junyeob; Hong, Sukjoon; Lee, Daehoo; Hotz, Nico; Lee, Ming-Tsang; Grigoropoulos, Costas P.; Ko, Seung Hwan

    2012-01-01

    Flexible electronics opened a new class of future electronics. The foldable, light and durable nature of flexible electronics allows vast flexibility in applications such as display, energy devices and mobile electronics. Even though conventional electronics fabrication methods are well developed for rigid substrates, direct application or slight modification of conventional processes for flexible electronics fabrication cannot work. The future flexible electronics fabrication requires totally new low-temperature process development optimized for flexible substrate and it should be based on new material too. Here we present a simple approach to developing a flexible electronics fabrication without using conventional vacuum deposition and photolithography. We found that direct metal patterning based on laser-induced local melting of metal nanoparticle ink is a promising low-temperature alternative to vacuum deposition– and photolithography-based conventional metal patterning processes. The “digital” nature of the proposed direct metal patterning process removes the need for expensive photomask and allows easy design modification and short turnaround time. This new process can be extremely useful for current small-volume, large-variety manufacturing paradigms. Besides, simple, scalable, fast and low-temperature processes can lead to cost-effective fabrication methods on a large-area polymer substrate. The developed process was successfully applied to demonstrate high-quality Ag patterning (2.1 µΩ·cm) and high-performance flexible organic field effect transistor arrays. PMID:22900011

  3. Digital Radiography: A Technology Overview

    NASA Astrophysics Data System (ADS)

    Arnold, Ben A.

    1982-12-01

    Digital radiography, a term hardly recognized two years ago, has grown to become the talk of the radiology community and the excitement of many commercial companies. M2st of this attention has been directed toward digital subtraction intravenous angiography), although during this same time period, a variety of digital radiography apparatus and image processing techniques have been under development. In November of 1980 at the RSNA Conference in Chicago, three commercial digital angiography systems were announced by Philips, Technicare and ADAC Corporations. During this same time period, the University of Arizona was discussing the concept of a photo electronic radiology department2, the University of Pittsburg and Stanford University were investigating line scan radiography3,4 and approximately five laboratories were carrying out clinical IV angiography with digital video systems.5-9 These developments followed basic research programs in digital electronic and computerized imaging at various locations around the world. 10-18 In the spring of 1981 we attempted to review the state of digital radiography, focusing on the various detector systems and image acquisition approaches.19 Since that time, rapid advancements in digital radiography have occurred. A major conference was held on digital radiography at Stanford UniversityzO, a new area detector system for digital radiography was announced by Fuji Film Corporation, clinical testing began on the Picker line scan digital chest unit21, and improvements were made in selenium detectors for digital radiography. Several additional companies announced digital video angiography systems, bringing the total now to approximately 15 companies worldwide. Digital video subtraction angiography is now well established as an important clinical diagnostic procedure and a variety of improvements and extensions of digital angiography systems are now ongoing. Digital acquisition and storage systems are increasing in both speed and

  4. Thermal Conductivity Measurement of Synthesized Mantle Minerals

    NASA Astrophysics Data System (ADS)

    Asimow, P. D.; Luo, S.; Mosenfelder, J. L.; Liu, W.; Staneff, G. D.; Ahrens, T. J.; Chen, G.

    2002-12-01

    Direct thermal conductivity (k) measurement of mantle minerals is crucial to constrain the thermal profile of the Earth as well as geodynamic studies of the mantle (e.g., to determine the Rayleigh number). We have embarked on systematic multi-anvil syntheses of dense polycrystalline specimens of mantle phases of adequate size and zero porosity for precise thermal conductivity measurements by the 3ω method (\\textit{Cahill and Pohl, Phys. Rev. B, 1987}) under elevated temperatures (T). Coesite and stishovite (see \\textit{Luo et al., GRL, 2002}) as well as majorite and wadsleyite have been synthesized; ringwoodite and perovskite are scheduled. Preliminary thermal conductivity measurements at ambient pressure on coesite (120 - 300 K, 9.53 Wm-1K-1 at 300 K) are consistent with prior room temperature data (\\textit{Yukutake & Shimada, PEPI, 1978}), while our stishovite data at 300 K appear to be low (1.96 Wm-1K-1). Efforts are being made to extend the measurement to higher temperatures (e.g., above Debye temperature Θ D), thus allowing determination of k(T) relationship (say, k~ T-n); success will depend on the decomposition kinetics of these metastable phases. The pressure dependence of k of these synthesized samples can also be measured (\\textit{e.g., Osako et al., HPMPS-6, 2002; Xu et al., EOS, 2001}). Recent thermal conductivity measurement on LiF and Al2O_3 from shock wave loading (\\textit{Holland & Ahrens, 1998}) is consistent with the modeling on MgO and Al2O_3 (\\textit{Manga & Jeanloz, JGR, 1997}) with classical theories. Thus, k values at modest pressures and T (say, above Θ D) would allow extrapolation of k to appropriate mantle conditions.

  5. Method of synthesizing tungsten nanoparticles

    SciTech Connect

    Thoma, Steven G; Anderson, Travis M

    2013-02-12

    A method to synthesize tungsten nanoparticles has been developed that enables synthesis of nanometer-scale, monodisperse particles that can be stabilized only by tetrahydrofuran. The method can be used at room temperature, is scalable, and the product concentrated by standard means. Since no additives or stabilizing surfactants are required, this method is particularly well suited for producing tungsten nanoparticles for dispersion in polymers. If complete dispersion is achieved due to the size of the nanoparticles, then the optical properties of the polymer can be largely maintained.

  6. Digital karyotyping.

    PubMed

    Wang, Tian-Li; Maierhofer, Christine; Speicher, Michael R; Lengauer, Christoph; Vogelstein, Bert; Kinzler, Kenneth W; Velculescu, Victor E

    2002-12-10

    Alterations in the genetic content of a cell are the underlying cause of many human diseases, including cancers. We have developed a method, called digital karyotyping, that provides quantitative analysis of DNA copy number at high resolution. This approach involves the isolation and enumeration of short sequence tags from specific genomic loci. Analysis of human cancer cells by using this method identified gross chromosomal changes as well as amplifications and deletions, including regions not previously known to be altered. Foreign DNA sequences not present in the normal human genome could also be readily identified. Digital karyotyping provides a broadly applicable means for systematic detection of DNA copy number changes on a genomic scale.

  7. Digital Radiography

    NASA Technical Reports Server (NTRS)

    1986-01-01

    System One, a digital radiography system, incorporates a reusable image medium (RIM) which retains an image. No film is needed; the RIM is read with a laser scanner, and the information is used to produce a digital image on an image processor. The image is stored on an optical disc. System allows the radiologist to "dial away" unwanted images to compare views on three screens. It is compatible with existing equipment and cost efficient. It was commercialized by a Stanford researcher from energy selective technology developed under a NASA grant.

  8. Digital numerically controlled oscillator

    NASA Technical Reports Server (NTRS)

    Cellier, A.; Huey, D. C.; Ma, L. N. (Inventor)

    1980-01-01

    The frequency and phase of an output signal from an oscillator circuit are controlled with accuracy by a digital input word. Positive and negative alterations in output frequency are both provided for by translating all values of input words so that they are positive. The oscillator reference frequency is corrected only in one direction, by adding phase to the output frequency of the oscillator. The input control word is translated to a single algebraic sign and the digital 1 is added thereto. The translated input control word is then accumulated. A reference clock signal having a frequency at an integer multiple of the desired frequency of the output signal is generated. The accumulated control word is then compared with a threshold level. The output signal is adjusted in a single direction by dividing the frequency of the reference clock signal by a first integer or by an integer different from the first integer.

  9. Synthesizing genetic sequential logic circuit with clock pulse generator

    PubMed Central

    2014-01-01

    Background Rhythmic clock widely occurs in biological systems which controls several aspects of cell physiology. For the different cell types, it is supplied with various rhythmic frequencies. How to synthesize a specific clock signal is a preliminary but a necessary step to further development of a biological computer in the future. Results This paper presents a genetic sequential logic circuit with a clock pulse generator based on a synthesized genetic oscillator, which generates a consecutive clock signal whose frequency is an inverse integer multiple to that of the genetic oscillator. An analogous electronic waveform-shaping circuit is constructed by a series of genetic buffers to shape logic high/low levels of an oscillation input in a basic sinusoidal cycle and generate a pulse-width-modulated (PWM) output with various duty cycles. By controlling the threshold level of the genetic buffer, a genetic clock pulse signal with its frequency consistent to the genetic oscillator is synthesized. A synchronous genetic counter circuit based on the topology of the digital sequential logic circuit is triggered by the clock pulse to synthesize the clock signal with an inverse multiple frequency to the genetic oscillator. The function acts like a frequency divider in electronic circuits which plays a key role in the sequential logic circuit with specific operational frequency. Conclusions A cascaded genetic logic circuit generating clock pulse signals is proposed. Based on analogous implement of digital sequential logic circuits, genetic sequential logic circuits can be constructed by the proposed approach to generate various clock signals from an oscillation signal. PMID:24884665

  10. Molecular scale electronics: syntheses and testing

    NASA Astrophysics Data System (ADS)

    Reinerth, William A.; Jones, LeRoy, II; Burgin, Timothy P.; Zhou, Chong-wu; Muller, C. J.; Deshpande, M. R.; Reed, Mark A.; Tour, James M.

    1998-09-01

    This paper describes four significant breakthroughs in the syntheses and testing of molecular scale electronic devices. The 16-mer of oligo(2-dodecylphenylene ethynylene) was prepared on Merrifields resin using the iterative divergent/convergent approach which significantly streamlines the preparation of this molecular scale wire. The formation of self-assembled monolayers and multilayers on gold surfaces of rigid rod conjugated oligomers that have thiol, 0957-4484/9/3/016/img11-dithiol, thioacetyl, or 0957-4484/9/3/016/img11-dithioacetyl end groups have been studied. The direct observation of charge transport through molecules of benzene-1, 4-dithiol, which have been self-assembled onto two facing gold electrodes, has been achieved. Finally, we report initial studies into what effect varying the molecular alligator clip has on the molecule scale wire's conductivity.

  11. Digital Tidbits

    ERIC Educational Resources Information Center

    Kumaran, Maha; Geary, Joe

    2011-01-01

    Technology has transformed libraries. There are digital libraries, electronic collections, online databases and catalogs, ebooks, downloadable books, and much more. With free technology such as social websites, newspaper collections, downloadable online calendars, clocks and sticky notes, online scheduling, online document sharing, and online…

  12. Digital books.

    PubMed

    Wink, Diane M

    2011-01-01

    In this bimonthly series, the author examines how nurse educators can use the Internet and Web-based computer technologies such as search, communication, and collaborative writing tools; social networking and social bookmarking sites; virtual worlds; and Web-based teaching and learning programs. This article describes digital books.

  13. Digital Badges

    ERIC Educational Resources Information Center

    Frederiksen, Linda

    2013-01-01

    Unlike so much of the current vocabulary in education and technology that seems to stir more confusion than clarity, most public service librarians may already have a general idea about digital badges. As visual representations of individual accomplishments, competencies or skills that are awarded by groups, institutions, or organizations, they…

  14. Digital Tidbits

    ERIC Educational Resources Information Center

    Kumaran, Maha; Geary, Joe

    2011-01-01

    Technology has transformed libraries. There are digital libraries, electronic collections, online databases and catalogs, ebooks, downloadable books, and much more. With free technology such as social websites, newspaper collections, downloadable online calendars, clocks and sticky notes, online scheduling, online document sharing, and online…

  15. Digital Batteries

    NASA Astrophysics Data System (ADS)

    Hubler, Alfred

    2009-03-01

    The energy density in conventional capacitors is limited by sparking. We present nano-capacitor arrays, where - like in laser diodes and quantum wells [1] - quantization prevents dielectric breakthrough. We show that the energy density and the power/weight ratio are very high, possibly larger than in hydrogen [2]. Digital batteries are a potential clean energy source for cars, laptops, and mobile devices. The technology is related to flash drives. However, because of the high energy density, safety is a concern. Digital batteries can be easily and safely charged and discharged. In the discharged state they pose no danger. Even if a charged digital battery were to explode, it would produce no radioactive waste, no long-term radiation, and probably could be designed to produce no noxious chemicals. We discuss methodologies to prevent shorts and other measures to make digital batteries safe. [1] H. Higuraskh, A. Toriumi, F. Yamaguchi, K. Kawamura, A. Hubler, Correlation Tunnel Device, U. S. Patent No. 5,679,961 (1997) [2] Alfred Hubler, http://server10.how-why.com/blog/

  16. Digital psychiatry.

    PubMed

    Tang, S; Helmeste, D

    2000-02-01

    The American managed care movement has been viewed as a big experiment and is being watched closely by the rest of the world. In the meanwhile, computer-based information technology (IT) is changing the practice of medicine, much more rapidly than managed care. A New World of digitized knowledge and information has been created. Although literature on IT in psychiatry is largely absent in peer-reviewed psychiatric journals, IT is finding its way into all aspects of medicine, particularly psychiatry. Telepsychiatry programs are becoming very popular. At the same time, medical information sites are flourishing and evolving into a new health-care industry. Patient-physician information asymmetry is decreasing as patients are gaining easy access to medical information hitherto only available to professionals. Thus, psychiatry is facing another paradigm shift, at a time when most attention has been focused on managed care. In this new digital world, knowledge and information are no longer the sole property of professionals. Value will migrate from traditional in-person office-based therapy to digital clinical products, from in-person library search and classroom didactic instruction to interactive on-line searches and distance learning. In this time of value migration, psychiatrists have to determine what their 'distinctive competence' is and where best to add value in the health-care delivery value chain. The authors assess the impact of IT on clinical psychiatry and review how clinical practice, education and research in psychiatry are expected to change in this emerging digital world.

  17. Designing Digital Resources to Effectively Scaffold Teachers' Learning

    ERIC Educational Resources Information Center

    Callahan, Cory

    2014-01-01

    This article synthesizes findings from an on-going line of inquiry investigating the potential of educatively scaffolded digital resources to help teachers understand and implement a complex model of history instruction, problem-based historical inquiry. The digital resources developed for this inquiry provided teachers with wise-practice…

  18. Knowledge and Processes That Predict Proficiency in Digital Literacy

    ERIC Educational Resources Information Center

    Bulger, Monica E.; Mayer, Richard E.; Metzger, Miriam J.

    2014-01-01

    Proficiency in digital literacy refers to the ability to read and write using online sources, and includes the ability to select sources relevant to the task, synthesize information into a coherent message, and communicate the message with an audience. The present study examines the determinants of digital literacy proficiency by asking 150…

  19. Designing Digital Resources to Effectively Scaffold Teachers' Learning

    ERIC Educational Resources Information Center

    Callahan, Cory

    2014-01-01

    This article synthesizes findings from an on-going line of inquiry investigating the potential of educatively scaffolded digital resources to help teachers understand and implement a complex model of history instruction, problem-based historical inquiry. The digital resources developed for this inquiry provided teachers with wise-practice…

  20. Digital Alchemy for Materials Design: Colloids and Beyond.

    PubMed

    van Anders, Greg; Klotsa, Daphne; Karas, Andrew S; Dodd, Paul M; Glotzer, Sharon C

    2015-10-27

    Starting with the early alchemists, a holy grail of science has been to make desired materials by modifying the attributes of basic building blocks. Building blocks that show promise for assembling new complex materials can be synthesized at the nanoscale with attributes that would astonish the ancient alchemists in their versatility. However, this versatility means that making a direct connection between building-block attributes and bulk structure is both necessary for rationally engineering materials and difficult because building block attributes can be altered in many ways. Here we show how to exploit the malleability of the valence of colloidal nanoparticle "elements" to directly and quantitatively link building-block attributes to bulk structure through a statistical thermodynamic framework we term "digital alchemy". We use this framework to optimize building blocks for a given target structure and to determine which building-block attributes are most important to control for self-assembly, through a set of novel thermodynamic response functions, moduli, and susceptibilities. We thereby establish direct links between the attributes of colloidal building blocks and the bulk structures they form. Moreover, our results give concrete solutions to the more general conceptual challenge of optimizing emergent behaviors in nature and can be applied to other types of matter. As examples, we apply digital alchemy to systems of truncated tetrahedra, rhombic dodecahedra, and isotropically interacting spheres that self-assemble diamond, fcc, and icosahedral quasicrystal structures, respectively. Although our focus is on colloidal systems, our methods generalize to any building blocks with adjustable interactions.

  1. Estimation of the amount of telomere molecules in different human age groups and the telomere increasing effect of acupuncture and shiatsu on St.36, using synthesized basic units of the human telomere molecules as reference control substances for the bi-digital O-ring test resonance phenomenon.

    PubMed

    Omura, Y; Shimotsura, Y; Ooki, M; Noguchi, T

    1998-01-01

    It is well established that the telomeres at the ends of chromosomes are composed of long arrays of (TTAGGG)n x (CCCTAA)n that form a nucleoprotein complex required for the replication and protection of chromosome ends. Throughout the cell cycle, telomeres also contain a protein component related to the proto-oncogene Myb that is known as TRF1 (telomere TTAGGG repeat binding factor 1) that binds to the duplex array of TTAGGG repeats in the telomere. Previous studies have shown that TRF1 appears to play a role in controlling the length of telomeres by acting as an inhibitor of telomerase. The amount of each of the TRF1(C-19) & TRF1(N-19) was identical to the amount of telomere of the same organ of the same apparently normal individual. Using synthesized basic unit of TTAGGG, as well as CCCTAA, as separate reference control substances for the Bi-Digital O-Ring Test of Resonance Phenomenon between 2 identical substances, we were able to non-invasively measure the approximate amount of TTAGGG and CCCTAA units, in both normal and cancerous human cells. We examined about 30 apparently normal subjects (both Asian and Caucasian in both sex). The subjects' ages ranged from infancy to 76 years. Each subject was first examined using TTAGGG as a control substance and then examined using CCCTAA as a control substance. The amount of telomere in various cancer tissues are almost always higher than that of normal tissue of the same organ. The measured amounts of both TTAGGG and CCCTAA were found to be in an average of 1500-1600 ng for human fetus or infancy and decreased with the advance of age in both sex with the exception of the heart, brain, eyes (retina), testes, and ovaries, which usually remain at the level of the infant, or reduced very little. Individuals in the same age group had a similar range of amounts of both TTAGGG and CCCTAA in the same organ of the same individual, (except for those with unusually low telomeres often had chronic degenerative diseases, and those

  2. Molecular Syntheses of Extended Materials

    NASA Astrophysics Data System (ADS)

    Paley, Daniel W.

    Bottom-up molecular synthesis is a route to chemically and crystallographically uniform polymers and solid-state materials. Through the use of molecular precursors, we gain atomic-level control of functionality and fine-tuning of the collective properties of materials. This dissertation presents two studies that demonstrate this approach. Ring-opening alkyne metathesis polymerization is a possible approach to monodisperse conjugated polymers, but its applications have been limited by difficult syntheses and high air sensitivity of known organometallic ROAMP initiators. We designed a dimeric, air-stable molybdenum alkylidyne with a tris(phenolate) supporting ligand. The precatalyst is activated by addition of methanol and polymerizes cyclooctynes with excellent chemical selectivity and functional group tolerance. The Nuckolls and Roy groups have introduced a new family of solid-state compounds synthesized from cobalt chalcogenide clusters Co6Q 8(PR3)6 and fullerenes. The first examples of these materials crystallized in superatom lattices with the symmetry of simple inorganic solids CdI2 (P-3m1) and NaCl (Fm-3m). This dissertation reveals that further members of the family feature extraordinary diversity of structure, including a pseudo-trigonal array of fulleride dimers in [Co 6Te8(PEt3)6]2[C140 ][C70]2 and a heterolayered van der Waals cocrystal [Co6Se8(PEt2phen)6][C 60]5. In addition to these unusual crystal structures, this dissertation presents a method for assigning redox states from crystallographic data in Co6Q8 clusters. Finally, a detailed guide to the collection and solution of single-crystal X-ray data is presented. The guide is intended for independent study by new crystallographers.

  3. Development of high precision digital driver of acoustic-optical frequency shifter for ROG

    NASA Astrophysics Data System (ADS)

    Zhang, Rong; Kong, Mei; Xu, Yameng

    2016-10-01

    We develop a high precision digital driver of the acoustic-optical frequency shifter (AOFS) based on the parallel direct digital synthesizer (DDS) technology. We use an atomic clock as the phase-locked loop (PLL) reference clock, and the PLL is realized by a dual digital phase-locked loop. A DDS sampling clock up to 320 MHz with a frequency stability as low as 10-12 Hz is obtained. By constructing the RF signal measurement system, it is measured that the frequency output range of the AOFS-driver is 52-58 MHz, the center frequency of the band-pass filter is 55 MHz, the ripple in the band is less than 1 dB@3MHz, the single channel output power is up to 0.3 W, the frequency stability is 1 ppb (1 hour duration), and the frequency-shift precision is 0.1 Hz. The obtained frequency stability has two orders of improvement compared to that of the analog AOFS-drivers. For the designed binary frequency shift keying (2-FSK) and binary phase shift keying (2-PSK) modulation system, the demodulating frequency of the input TTL synchronous level signal is up to 10 kHz. The designed digital-bus coding/decoding system is compatible with many conventional digital bus protocols. It can interface with the ROG signal detecting software through the integrated drive electronics (IDE) and exchange data with the two DDS frequency-shift channels through the signal detecting software.

  4. A compact wideband precision impedance measurement system based on digital auto-balancing bridge

    NASA Astrophysics Data System (ADS)

    Hu, Binxin; Wang, Jinyu; Song, Guangdong; Zhang, Faxiang

    2016-05-01

    The ac impedance spectroscopy measurements are predominantly taken by using impedance analyzers based on analog auto-balancing bridge. However, those bench-top analyzers are generally complicated, bulky and expensive, thus limiting their usage in industrial field applications. This paper presents the development of a compact wideband precision measurement system based on digital auto-balancing bridge. The methods of digital auto-balancing bridge and digital lock-in amplifier are analyzed theoretically. The overall design and several key sections including null detector, direct digital synthesizer-based sampling clock, and digital control unit are introduced in detail. The results show that the system achieves a basic measurement accuracy of 0.05% with a frequency range of 20 Hz-2 MHz. The advantages of versatile measurement capacity, fast measurement speed, small size and low cost make it quite suitable for industrial field applications. It is demonstrated that this system is practical and effective by applying in determining the impedance-temperature characteristic of a motor starter PTC thermistor.

  5. Digital storytelling: an innovative technological approach to nursing education.

    PubMed

    Price, Deborah M; Strodtman, Linda; Brough, Elizabeth; Lonn, Steven; Luo, Airong

    2015-01-01

    This study investigated the impact of using digital stories in promoting deeper understanding in nursing students about palliative care concepts. Students (N = 134) created a 5-minute narrated digital story utilizing VoiceThread technology that synthesized and applied knowledge that had been presented in class and course readings. Postsurvey and focus group evaluation data revealed that through the writing and sharing of digital stories, students embraced the personal and complex nature of palliative care.

  6. The State of the Art and Practice in Digital Preservation

    PubMed Central

    Lee, Kyong-Ho; Slattery, Oliver; Lu, Richang; Tang, Xiao; McCrary, Victor

    2002-01-01

    The goal of digital preservation is to ensure long-term access to digitally stored information. In this paper, we present a survey of techniques used in digital preservation. We also introduce representative digital preservation projects and case studies that provide insight into the advantages and disadvantages of different preservation strategies. Finally, the pros and cons of current strategies, critical issues for digital preservation, and future directions are discussed. PMID:27446721

  7. Digital karyotyping

    PubMed Central

    Wang, Tian-Li; Maierhofer, Christine; Speicher, Michael R.; Lengauer, Christoph; Vogelstein, Bert; Kinzler, Kenneth W.; Velculescu, Victor E.

    2002-01-01

    Alterations in the genetic content of a cell are the underlying cause of many human diseases, including cancers. We have developed a method, called digital karyotyping, that provides quantitative analysis of DNA copy number at high resolution. This approach involves the isolation and enumeration of short sequence tags from specific genomic loci. Analysis of human cancer cells by using this method identified gross chromosomal changes as well as amplifications and deletions, including regions not previously known to be altered. Foreign DNA sequences not present in the normal human genome could also be readily identified. Digital karyotyping provides a broadly applicable means for systematic detection of DNA copy number changes on a genomic scale. PMID:12461184

  8. Digital tachometer

    NASA Astrophysics Data System (ADS)

    Shirokov, B.

    1984-03-01

    A tachometer with digital indication was built for measuring the speed of automobile engines with only two digits in the rpm readout. It consists of a Schmitt trigger for shaping input pulses, a pulse counter, a cycle time setting multivibrator and a readout time setting multivibrator, a stabilizer, a flicker suppressor, and a capacitive transducer. The instrument operates from a 12 V battery and draws 180 mA. The transducer includes a 30 to 50 turns coil of PEL 0.5 wire wound around the conductor which connects the ignition coil to the engine distributor and its transistor is mounted on a fin-type heat sink. Tuneup of the tachometer involves matching the transducer capacitor for maximum voltage at minimum current and trimming the readout time setting multivibrator with its adjustable resistor for a 1.5 readout with a 50 Hz input signal.

  9. [Digital radiography].

    PubMed

    Haendle, J

    1983-03-01

    Digital radiography is a generally accepted term comprising all x-ray image systems producing a projected image which resembles the conventional x-ray film image, and which are linked to any type of digital image processing. Fundamental criteria of differentiation are based on the production and detection method of the x-ray image. Various systems are employed, viz. the single-detector, line-detector or fanbeam detector and the area-beam or area-detector image converters, which differ from one another mainly in the manner of conversion of the radiation produced by the x-ray tube. The article also deals with the pros and cons of the various principles, the multitude of systems employed, and the varying frequency of their use in x-ray diagnosis work.

  10. Synthese de champs sonores adaptative

    NASA Astrophysics Data System (ADS)

    Gauthier, Philippe-Aubert

    La reproduction de champs acoustiques est une approche physique au probleme technologique de la spatialisation sonore. Cette these concerne l'aspect physique de la reproduction de champs acoustiques. L'objectif principal est l'amelioration de la reproduction de champs acoustiques par "synthese de champs acoustiques" ("Wave Field Synthesis", WFS), une approche connue, basee sur des hypotheses de champ libre, a l'aide du controle actif par l'ajout de capteurs de l'erreur de reproduction et d'une boucle fermee. Un premier chapitre technique (chapitre 4) expose les resultats d'appreciation objective de la WFS par simulations et mesures experimentales. L'effet indesirable de la salle de reproduction sur les qualites objectives de la WFS fut illustre. Une premiere question de recherche fut ensuite abordee (chapitre 5), a savoir s'il est possible de reproduire des champs progressifs en salle dans un paradigme physique de controle actif: cette possibilite fut prouvee. L'approche technique privilegiee, "synthese de champs adaptative" ("Adaptive Wave Field Synthesis" [AWFS]), fut definie, puis simulee (chapitre 6). Cette approche d'AWFS comporte une originalite en controle actif et en reproduction de champs acoustiques: la fonction cout quadratique representant la minimisation des erreurs de reproduction inclut une regularisation de Tikhonov avec solution a priori qui vient de la WFS. L'etude de l'AWFS a l'aide de la decomposition en valeurs singulieres (chapitre 7) a permis de comprendre les mecanismes propres a l'AWFS. C'est la deuxieme principale originalite de la these. L'algorithme FXLMS (LMS et reference filtree) est modifie pour l'AWFS (chapitre 8). Le decouplage du systeme par decomposition en valeurs singulieres est illustre dans le domaine du traitement de signal et l'AWFS basee sur le controle independant des modes de rayonnement est simulee (chapitre 8). Ce qui constitue la troisieme originalite principale de cette these. Ces simulations du traitement de signal

  11. Digital Earth

    NASA Astrophysics Data System (ADS)

    de La Beaujardiere, J.

    2001-05-01

    Digital Earth (DE) seeks to make geospatial information broadly and easily available. Vast amounts of natural and cultural information are gathered about the Earth, but it is often difficult to find needed data, to share knowledge across disciplines, and to combine information from several sources. DE defines a framework for interoperability by selecting relevant open standards from the information technology community. These standards specify the technical means by which publishers can provide or sell their data, and by which client applications can find and access data in an automated fashion. The standardized DE framework enables many types of clients--from web browsers to museum kiosks to research-grade virtual environments--to use a common geospatial information infrastructure. Digital Earth can benefit Earth system education in general, and DLESE in particular, in several ways. First, educators, students and creators of instructional material will benefit from standardized access to georeferenced data. Secondly, educational lesson plans that focus on a region or aspect of the Earth can themselves be considered geospatial information resources that could be cataloged and retrieved through DE. Finally, general public knowledge about our planet will by increased by Digital Earth.

  12. Diameter Controlled of Carbon Nanotubes Synthesized on Nanoporous Silicon Support

    NASA Astrophysics Data System (ADS)

    Asli, N. A.; Shamsudin, M. S.; Maryam, M.; Yusop, S. F. M.; Suriani, A. B.; Rusop, M.; Abdullah, S.

    2013-06-01

    Carbon nanotubes (CNTs) have been successfully synthesized on nanoporous silicon template (NPSiT) using botanical source, camphor oil. Diameter of CNTs synthesized was controlled by pore size of NPSiT prepared by photo-electrochemical anodization method. The diameter of CNTs grown on different NPSiT corresponded to the pore diameter of NPSiT. FESEM images showed self-organized bundles of fiber-like structures of CNTs with diameter of around 20nm which were successfully grown directly on nanoporous silicon while raman spectra obtained ratio of ID/IG at 0.67.

  13. Oligodendrocyte Precursor Cells Synthesize Neuromodulatory Factors

    PubMed Central

    Sakry, Dominik; Yigit, Hatice; Dimou, Leda; Trotter, Jacqueline

    2015-01-01

    NG2 protein-expressing oligodendrocyte progenitor cells (OPC) are a persisting and major glial cell population in the adult mammalian brain. Direct synaptic innervation of OPC by neurons throughout the brain together with their ability to sense neuronal network activity raises the question of additional physiological roles of OPC, supplementary to generating myelinating oligodendrocytes. In this study we investigated whether OPC express neuromodulatory factors, typically synthesized by other CNS cell types. Our results show that OPC express two well-characterized neuromodulatory proteins: Prostaglandin D2 synthase (PTGDS) and neuronal Pentraxin 2 (Nptx2/Narp). Expression levels of the enzyme PTGDS are influenced in cultured OPC by the NG2 intracellular region which can be released by cleavage and localizes to glial nuclei upon transfection. Furthermore PTGDS mRNA levels are reduced in OPC from NG2-KO mouse brain compared to WT cells after isolation by cell sorting and direct analysis. These results show that OPC can contribute to the expression of these proteins within the CNS and suggest PTGDS expression as a downstream target of NG2 signaling. PMID:25966014

  14. Laser-synthesized epitaxial graphene.

    PubMed

    Lee, Sangwon; Toney, Michael F; Ko, Wonhee; Randel, Jason C; Jung, Hee Joon; Munakata, Ko; Lu, Jesse; Geballe, Theodore H; Beasley, Malcolm R; Sinclair, Robert; Manoharan, Hari C; Salleo, Alberto

    2010-12-28

    Owing to its unique electronic properties, graphene has recently attracted wide attention in both the condensed matter physics and microelectronic device communities. Despite intense interest in this material, an industrially scalable graphene synthesis process remains elusive. Here, we demonstrate a high-throughput, low-temperature, spatially controlled and scalable epitaxial graphene (EG) synthesis technique based on laser-induced surface decomposition of the Si-rich face of a SiC single-crystal. We confirm the formation of EG on SiC as a result of excimer laser irradiation by using reflection high-energy electron diffraction (RHEED), Raman spectroscopy, synchrotron-based X-ray diffraction, transmission electron microscopy (TEM), and scanning tunneling microscopy (STM). Laser fluence controls the thickness of the graphene film down to a single monolayer. Laser-synthesized graphene does not display some of the structural characteristics observed in EG grown by conventional thermal decomposition on SiC (0001), such as Bernal stacking and surface reconstruction of the underlying SiC surface.

  15. Land Treatment Digital Library

    USGS Publications Warehouse

    Pilliod, David S.

    2009-01-01

    Across the country, public land managers make hundreds of decisions each year that influence landscapes and ecosystems within the lands they manage. Many of these decisions involve vegetation manipulations known as land treatments. Land treatments include activities such as removal or alteration of plant biomass, seeding burned areas, and herbicide applications. Data on these land treatments are usually stored at local offices, and gathering information across large spatial areas can be difficult. There is a need to centralize and store treatment data for Federal agencies involved in land treatments because these data are useful to land managers for policy and management and to scientists for developing sampling designs and studies. The Land Treatment Digital Library (LTDL) was created by the U.S. Geological Survey (USGS) to catalog information about land treatments on Federal lands in the western United States for all interested parties. The flexible framework of the library allows for the storage of a wide variety of data in different formats. The LTDL currently stores previously established land treatments or what often are called legacy data. The project was developed and has been refined based on feedback from partner agencies and stakeholders, with opportunity for the library holdings to expand as new information becomes available. The library contains data in text, tabular, spatial, and image formats. Specific examples include project plans and implementation reports, monitoring data, spatial data files from geographic information systems, digitized paper maps, and digital images of land treatments. The data are entered by USGS employees and are accessible through a searchable web site. The LTDL can be used to respond to information requests, conduct analyses and other forms of information syntheses, produce maps, and generate reports for DOI managers and scientists and other authorized users.

  16. The digital Emily project: achieving a photorealistic digital actor.

    PubMed

    Alexander, Oleg; Rogers, Mike; Lambeth, William; Chiang, Jen-Yuan; Ma, Wan-Chun; Wang, Chuan-Chang; Debevec, Paul

    2010-01-01

    The Digital Emily Project uses advanced face scanning, character rigging, performance capture, and compositing to achieve one of the world's first photorealistic digital facial performances. The project scanned the geometry and reflectance of actress Emily O'Brien's face in 33 poses, showing different emotions, gaze directions, and lip formations in a light stage. These high-resolution scans-accurate to skin pores and fine wrinkles-became the basis for building a blendshape-based facial-animation rig whose expressions closely matched the scans. The blendshape rig drove displacement maps to add dynamic surface detail. A video-based facial animation system animated the face according to the performance in a reference video, and the digital face was tracked onto the video's motion and rendered under the same illumination. The result was a realistic 3D digital facial performance credited as one of the first to cross the "uncanny valley" between animated and fully human performances.

  17. X-ray visible and uniform alginate microspheres loaded with in situ synthesized BaSO4 nanoparticles for in vivo transcatheter arterial embolization.

    PubMed

    Wang, Qin; Qian, Kun; Liu, Shanshan; Yang, Yajiang; Liang, Bin; Zheng, Chuansheng; Yang, Xiangliang; Xu, Huibi; Shen, Amy Q

    2015-04-13

    The lack of noninvasive tracking and mapping the fate of embolic agents has restricted the development and further applications of the transcatheter arterial embolization (TAE) therapy. In this work, inherent radiopaque embolic material, barium alginate (ALG) microspheres loaded with in situ synthesized BaSO4 (denoted as BaSO4/ALG microspheres), have been synthesized by a one-step droplet microfluidic technique. One of the advantages of our microfluidic approach is that radiopaque BaSO4 is in the form of nanoparticles and well dispersed inside ALG microspheres, thereby greatly enhancing the imaging quality. The crystal structure of in situ synthesized BaSO4 nanoparticles in ALG microspheres is confirmed by X-ray diffraction analysis. Results of in vitro and in vivo assays from digital subtraction angiography and computed tomography scans demonstrate that BaSO4/ALG microspheres possess excellent visibility under X-ray. Histopathological analysis verifies that the embolic efficacy of BaSO4/ALG microspheres is similar to that of commercially available alginate microsphere embolic agents. Furthermore, the visibility of radiopaque BaSO4/ALG microspheres under X-ray promises the direct detection of the embolic efficiency and position of embolic microspheres after embolism, which offers great promises in direct real-time in vivo investigations for TAE.

  18. Synthesizing Diamond from Liquid Feedstock

    NASA Technical Reports Server (NTRS)

    Tzeng, Yonhua

    2005-01-01

    A relatively economical method of chemical vapor deposition (CVD) has been developed for synthesizing diamond crystals and films. Unlike prior CVD methods for synthesizing diamond, this method does not require precisely proportioned flows of compressed gas feedstocks or the use of electrical discharges to decompose the feedstocks to obtain free radicals needed for deposition chemical reactions. Instead, the feedstocks used in this method are mixtures of common organic liquids that can be prepared in advance, and decomposition of feedstock vapors is effected simply by heating. The feedstock used in this method is a solution comprising between 90 and 99 weight percent of methanol and the balance of one or more other oxyhydrocarbons that could include ethanol, isopropanol, and/or acetone. This mixture of compounds is chosen so that dissociation of molecules results in the desired proportions of carbon-containing radicals (principally, CH3) and of OH, H, and O radicals. Undesirably, the CVD temperature and pressure conditions thermodynamically favor the growth of graphite over the growth of diamond. The H radicals are desirable because they help to stabilize the growing surface of diamond by shifting the thermodynamic balance toward favoring the growth of diamond. The OH and O radicals are desirable because they preferentially etch graphite and other non-diamond carbon, thereby helping to ensure the net deposition of pure diamond. The non-methanol compounds are included in the solution because (1) methanol contains equal numbers of C and O atoms; (2) an excess of C over O is needed to obtain net deposition of diamond; and (3) the non-methanol molecules contain multiple carbon atoms for each oxygen atom and thus supply the needed excess carbon A typical apparatus used in this method includes a reservoir containing the feedstock liquid and a partially evacuated stainless-steel reaction chamber. The reservoir is connected to the chamber via tubing and a needle valve or

  19. Integrating TV/digital data spectrograph system

    NASA Technical Reports Server (NTRS)

    Duncan, B. J.; Fay, T. D.; Miller, E. R.; Wamsteker, W.; Brown, R. M.; Neely, P. L.

    1975-01-01

    A 25-mm vidicon camera was previously modified to allow operation in an integration mode for low-light-level astronomical work. The camera was then mated to a low-dispersion spectrograph for obtaining spectral information in the 400 to 750 nm range. A high speed digital video image system was utilized to digitize the analog video signal, place the information directly into computer-type memory, and record data on digital magnetic tape for permanent storage and subsequent analysis.

  20. Digital processing system for developing countries

    NASA Technical Reports Server (NTRS)

    Nanayakkara, C.; Wagner, H.

    1977-01-01

    An effort was undertaken to perform simple digital processing tasks using pre-existing general purpose digital computers. An experimental software package, LIGMALS, was obtained and modified for this purpose. The resulting software permits basic processing tasks to be performed including level slicing, gray mapping and ratio processing. The experience gained in this project indicates a possible direction which may be used by other developing countries to obtain digital processing capabilities.

  1. Force XXI: Directions in Digitization - Symposium Report.

    DTIC Science & Technology

    1996-08-21

    staff is a target for these efficiencies. A Task Force commander should be able to manage a greater number of units with the assistance of fewer...power systems as we are better able to pinpoint enemy targets and coordinate JAAT missions. There are still many questions about what changes may take...warfare is all about "sensor to shooter - getting steel on target ...[T]he TOC is not important, the information is what’s important...and you got to

  2. Superconductor Digital-RF Receiver Systems

    NASA Astrophysics Data System (ADS)

    Mukhanov, Oleg A.; Kirichenko, Dmitri; Vernik, Igor V.; Filippov, Timur V.; Kirichenko, Alexander; Webber, Robert; Dotsenko, Vladimir; Talalaevskii, Andrei; Tang, Jia Cao; Sahu, Anubhav; Shevchenko, Pavel; Miller, Robert; Kaplan, Steven B.; Sarwana, Saad; Gupta, Deepnarayan

    Digital superconductor electronics has been experiencing rapid maturation with the emergence of smaller-scale, lower-cost communications applications which became the major technology drivers. These applications are primarily in the area of wireless communications, radar, and surveillance as well as in imaging and sensor systems. In these areas, the fundamental advantages of superconductivity translate into system benefits through novel Digital-RF architectures with direct digitization of wide band, high frequency radio frequency (RF) signals. At the same time the availability of relatively small 4K cryocoolers has lowered the foremost market barrier for cryogenically-cooled digital electronic systems. Recently, we have achieved a major breakthrough in the development, demonstration, and successful delivery of the cryocooled superconductor digital-RF receivers directly digitizing signals in a broad range from kilohertz to gigahertz. These essentially hybrid-technology systems combine a variety of superconductor and semiconductor technologies packaged with two-stage commercial cryocoolers: cryogenic Nb mixed-signal and digital circuits based on Rapid Single Flux Quantum (RSFQ) technology, room-temperature amplifiers, FPGA processing and control circuitry. The demonstrated cryocooled digital-RF systems are the world's first and fastest directly digitizing receivers operating with live satellite signals in X-band and performing signal acquisition in HF to L-band at ˜30GHz clock frequencies.

  3. Scanning for Digitization Projects

    ERIC Educational Resources Information Center

    Wentzel, Larry

    2007-01-01

    Librarians and archivists find themselves facing the prospect of digitization. Everyone is doing it, everyone needs it. Discussions rage nationally and internationally concerning what to digitize and the best means to present and retain digital objects. Digitization is the act of making something digital, expressing a physical object "in numerical…

  4. Scanning for Digitization Projects

    ERIC Educational Resources Information Center

    Wentzel, Larry

    2007-01-01

    Librarians and archivists find themselves facing the prospect of digitization. Everyone is doing it, everyone needs it. Discussions rage nationally and internationally concerning what to digitize and the best means to present and retain digital objects. Digitization is the act of making something digital, expressing a physical object "in numerical…

  5. Digital hydraulic valving system. [design and development

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The design and development are reported of a digital hydraulic valving system that would accept direct digital inputs. Topics include: summary of contractual accomplishments, design and function description, valve parameters and calculations, conclusions, and recommendations. The electrical control circuit operating procedure is outlined in an appendix.

  6. Biologically-synthesized inorganic nanomaterials

    NASA Astrophysics Data System (ADS)

    Kramer, Ryan M.; Stone, Morley O.; Naik, Rajesh R.

    2004-06-01

    A hallmark of biological systems is their ability to self-assemble. This self-assembly can occur on the molecular, macromolecular and mesoscale. In this work, we have chosen to exploit biology's ability to self-assemble by incorporating additional functionality within the final structure. Our research efforts have been directed at not only understanding how biological organisms control nucleation and growth of inorganic materials, but also how this activity can be controlled in vitro. In previous work, we have demonstrated how peptides can be selected from a combinatorial library that possesses catalytic activity with respect to inorganic nucleation and deposition. We have engineered some of these peptide sequences into self-assembling protein structures. The goal of the project was to create an organic/inorganic hybrid that retained the "memory" properties of the organic, but possessed the superior optical and electronic properties of the inorganic.

  7. Digital Holography Display (2)

    NASA Astrophysics Data System (ADS)

    Lee, Cheok Peng; Asundi, A.; Yu, Yang; Xiao, Zhen Zhong

    This paper describes the extension work from the last Digital Holography Projector System. From the developed works shows that, some unforeseen factors have created the difficulties for the system alignment. Such factors are the DMD frame rate, light source and diffractive zero order. It is really the challenging development works to achieve the virtual 3D model display on the high speed rotation screen. The three most key factors are emphasizing: 1) The display device's frame rate; 2) The light source orientation angle; and 3) The zero order filtering optic. 1) This device's is the digital micro mirror, in short is DMD. It is the high speed switching device has developed by the most recent technology. The switching frame rate can go up as high as 291fps. At first, the 8 bits depth file must be digitalized and stored for DMD onboard Ram. The digitalized data are transmitting from the PC USB to DMD onboard Ram. Instead of the data are downloading directly from the PC to DVI or VGA during display, this downloading method cause slower down the display speed, which is the common frame rate of 30 Hz. Next, the onboard Ram data then transfer to the DMD mirror's for display, at the 8 bits 291 fps speed. At this frame rate, the display 2D image can almost cover for 10 of out of the 360 0 in 1 revolution. 2) This laser light source must be installed such that free for orientated in any arbitrary angle from 220 to 450. Which is normalized to the DMD mirrors and the brief sketch show on figure (a). The purpose of orientated the light source is ensure that multi diffractive order would be reflected straight from the mirrors. (This multi diffractive order is the phenomenon of the digital micro mirror's characteristic). This mean, the reconstruct images would be followed the DMD normalized direction reflected up to fibre conduit. Moreover, this orientated method install of the laser light source is making space for other optical lenses or device driver/controller. Because, all

  8. The counting recursive digital filter.

    NASA Technical Reports Server (NTRS)

    Zohar, S.

    1973-01-01

    Analysis of the bit-level operations involved in the convolutions realizing recursive digital filters leads to hardware designs of such filters based on the operation of counting. Various designs realizing both the canonic and 'direct' forms are presented with particular emphasis on low-cost low-speed high-flexibility machines.

  9. Digital structural

    USGS Publications Warehouse

    Dohm, J.M.; Anderson, R.C.; Tanaka, K.L.

    1998-01-01

    Magmatic and tectonic activity have both contributed significantly to the surface geology of Mars. Digital structural mapping techniques have now been used to classify and date centers of tectonic activity in the western equatorial region. For example, our results show a center of tectonic activity at Valles Marineris, which may be associated with uplift caused by intrusion. Such evidence may help explain, in part, the development of the large troughs and associated outflow channels and chaotic terrain. We also find a local centre of tectonic activity near the source region of Warrego Valles. Here, we suggest that the valley system may have resulted largely from intrusive-related hydrothermal activity. We hope that this work, together with the current Mars Global Surveyor mission, will lead to a better understanding of the geological processes that shaped the Martian surface.

  10. Digital demodulator

    NASA Technical Reports Server (NTRS)

    Shull, T. A. (Inventor)

    1982-01-01

    A digital demodulator for converting pulse code modulated data from phase shift key (PSK) to non return to zero (NRZ) and to biphase data is described. The demodulator is composed of standard integrated logic circuits. The key to the demodulation function is a pair of cross coupled one shot multivibrators and which with a flip-flop produce the NRZ-L is all that is required, the circuitry is greatly simplified and the 2(v) times bit rate contraint can be removed from the carrier. A flip-flop, an OR gate, and AND gate and a binary counter generate the bit rate clock (BTCK) for the NRZ-L. The remainder of the circuitry is for converting the NRZ-L and BTCK into biphase data. The device was designed for use in the space shuttle bay environment measurements.

  11. Digital Avionics

    NASA Technical Reports Server (NTRS)

    Koelbl, Terry G.; Ponchak, Denise; Lamarche, Teresa

    2002-01-01

    The field of digital avionics experienced another year of important advances in civil aviation, military systems, and space applications. As a result of the events of 9/11/2001, NASA has pursued activities to apply its aerospace technologies toward improved aviation security. Both NASA Glenn Research Center and Langley Research Center have performed flight research demonstrations using advanced datalink concepts to transmit live pictures from inside a jetliner, and to downlink the contents of the plane's 'black box' recorder in real time. The U.S. Navy and General Electric demonstrated survivable engine control (SEC) algorithms during engine ground tests at the Weapons Survivability Laboratory at China Lake. The scientists at Boeing Satellite Systems advanced the field of stellar inertial technology with the development of a new method for positioning optical star trackers on satellites.

  12. Digital Avionics

    NASA Technical Reports Server (NTRS)

    Koelbl, Terry G.; Ponchak, Denise; Lamarche, Teresa

    2003-01-01

    Digital Avionics activities played an important role in the advancements made in civil aviation, military systems, and space applications. This document profiles advances made in each of these areas by the aerospace industry, NASA centers, and the U.S. military. Emerging communication technologies covered in this document include Internet connectivity onboard aircraft, wireless broadband communication for aircraft, and a mobile router for aircraft to communicate in multiple communication networks over the course of a flight. Military technologies covered in this document include avionics for unmanned combat air vehicles and microsatellites, and head-up displays. Other technologies covered in this document include an electronic flight bag for the Boeing 777, and surveillance systems for managing airport operations.

  13. Digital Avionics

    NASA Technical Reports Server (NTRS)

    Koelbl, Terry G.; Ponchak, Denise; Lamarche, Teresa

    2002-01-01

    The field of digital avionics experienced another year of important advances in civil aviation, military systems, and space applications. As a result of the events of 9/11/2001, NASA has pursued activities to apply its aerospace technologies toward improved aviation security. Both NASA Glenn Research Center and Langley Research Center have performed flight research demonstrations using advanced datalink concepts to transmit live pictures from inside a jetliner, and to downlink the contents of the plane's 'black box' recorder in real time. The U.S. Navy and General Electric demonstrated survivable engine control (SEC) algorithms during engine ground tests at the Weapons Survivability Laboratory at China Lake. The scientists at Boeing Satellite Systems advanced the field of stellar inertial technology with the development of a new method for positioning optical star trackers on satellites.

  14. Digital demodulator

    NASA Astrophysics Data System (ADS)

    Shull, T. A.

    1982-01-01

    A digital demodulator for converting pulse code modulated data from phase shift key (PSK) to non return to zero (NRZ) and to biphase data is described. The demodulator is composed of standard integrated logic circuits. The key to the demodulation function is a pair of cross coupled one shot multivibrators and which with a flip-flop produce the NRZ-L is all that is required, the circuitry is greatly simplified and the 2(v) times bit rate contraint can be removed from the carrier. A flip-flop, an OR gate, and AND gate and a binary counter generate the bit rate clock (BTCK) for the NRZ-L. The remainder of the circuitry is for converting the NRZ-L and BTCK into biphase data. The device was designed for use in the space shuttle bay environment measurements.

  15. Digital linear actuator

    SciTech Connect

    Birchard, W.G.

    1988-06-21

    A digital actuator is described comprising: (a) digital actuator cells, each digital actuator cell having an axis of expansion and first and second end surfaces; (b) third connecting means, each for connecting the first end surface of one digital actuator cell to the second end surface of an adjacent actuator cell, the plurality of digital actuator cells being connected in series by respective ones of the third connecting means to form the digital linear actuator.

  16. Synthesizing Regression Results: A Factored Likelihood Method

    ERIC Educational Resources Information Center

    Wu, Meng-Jia; Becker, Betsy Jane

    2013-01-01

    Regression methods are widely used by researchers in many fields, yet methods for synthesizing regression results are scarce. This study proposes using a factored likelihood method, originally developed to handle missing data, to appropriately synthesize regression models involving different predictors. This method uses the correlations reported…

  17. "Comments on Slavin": Synthesizing Causal Inferences

    ERIC Educational Resources Information Center

    Briggs, Derek C.

    2008-01-01

    When causal inferences are to be synthesized across multiple studies, efforts to establish the magnitude of a causal effect should be balanced by an effort to evaluate the generalizability of the effect. The evaluation of generalizability depends on two factors that are given little attention in current syntheses: construct validity and external…

  18. Composites comprising biologically-synthesized nanomaterials

    DOEpatents

    Curran, Seamus; Dias, Sampath; Blau, Werner; Wang, Jun; Oremland, Ronald S; Baesman, Shaun

    2013-04-30

    The present disclosure describes composite materials containing a polymer material and a nanoscale material dispersed in the polymer material. The nanoscale materials may be biologically synthesized, such as tellurium nanorods synthesized by Bacillus selenitireducens. Composite materials of the present disclosure may have optical limiting properties and find use in optical limiting devices.

  19. Synthesizing Regression Results: A Factored Likelihood Method

    ERIC Educational Resources Information Center

    Wu, Meng-Jia; Becker, Betsy Jane

    2013-01-01

    Regression methods are widely used by researchers in many fields, yet methods for synthesizing regression results are scarce. This study proposes using a factored likelihood method, originally developed to handle missing data, to appropriately synthesize regression models involving different predictors. This method uses the correlations reported…

  20. Synthesizing topological structures containing RNA.

    PubMed

    Liu, Di; Shao, Yaming; Chen, Gang; Tse-Dinh, Yuk-Ching; Piccirilli, Joseph A; Weizmann, Yossi

    2017-03-31

    Though knotting and entanglement have been observed in DNA and proteins, their existence in RNA remains an enigma. Synthetic RNA topological structures are significant for understanding the physical and biological properties pertaining to RNA topology, and these properties in turn could facilitate identifying naturally occurring topologically nontrivial RNA molecules. Here we show that topological structures containing single-stranded RNA (ssRNA) free of strong base pairing interactions can be created either by configuring RNA-DNA hybrid four-way junctions or by template-directed synthesis with a single-stranded DNA (ssDNA) topological structure. By using a constructed ssRNA knot as a highly sensitive topological probe, we find that Escherichia coli DNA topoisomerase I has low RNA topoisomerase activity and that the R173A point mutation abolishes the unknotting activity for ssRNA, but not for ssDNA. Furthermore, we discover the topological inhibition of reverse transcription (RT) and obtain different RT-PCR patterns for an ssRNA knot and circle of the same sequence.

  1. Synthesizing topological structures containing RNA

    NASA Astrophysics Data System (ADS)

    Liu, Di; Shao, Yaming; Chen, Gang; Tse-Dinh, Yuk-Ching; Piccirilli, Joseph A.; Weizmann, Yossi

    2017-03-01

    Though knotting and entanglement have been observed in DNA and proteins, their existence in RNA remains an enigma. Synthetic RNA topological structures are significant for understanding the physical and biological properties pertaining to RNA topology, and these properties in turn could facilitate identifying naturally occurring topologically nontrivial RNA molecules. Here we show that topological structures containing single-stranded RNA (ssRNA) free of strong base pairing interactions can be created either by configuring RNA-DNA hybrid four-way junctions or by template-directed synthesis with a single-stranded DNA (ssDNA) topological structure. By using a constructed ssRNA knot as a highly sensitive topological probe, we find that Escherichia coli DNA topoisomerase I has low RNA topoisomerase activity and that the R173A point mutation abolishes the unknotting activity for ssRNA, but not for ssDNA. Furthermore, we discover the topological inhibition of reverse transcription (RT) and obtain different RT-PCR patterns for an ssRNA knot and circle of the same sequence.

  2. Digital Self-Harm Among Adolescents.

    PubMed

    Patchin, Justin W; Hinduja, Sameer

    2017-09-18

    Despite increased media and scholarly attention to digital forms of aggression directed toward adolescents by their peers (e.g., cyberbullying), very little research has explored digital aggression directed toward oneself. "Digital self-harm" is the anonymous online posting, sending, or otherwise sharing of hurtful content about oneself. The current study examined the extent of digital self-harm among adolescents. Survey data were obtained in 2016 from a nationally representative sample of 5,593 American middle and high school students (12-17 years old). Logistic regression analysis was used to identify correlates of participation in digital self-harm. Qualitative responses were also reviewed to better understand motivations for digital self-harm. About 6% of students have anonymously posted something online about themselves that was mean. Males were significantly more likely to report participation (7.1% compared to 5.3%). Several statistically significant correlates of involvement in digital self-harm were identified, including sexual orientation, experience with school bullying and cyberbullying, drug use, participation in various forms of adolescent deviance, and depressive symptoms. Digital self-harm is a new problem that demands additional scholarly attention. A deeper inquiry as to the motivations behind this behavior, and how it correlates to offline self-harm and suicidal ideation, can help direct mental health professionals toward informed prevention approaches. Copyright © 2017 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  3. A PLL Synthesizer with Learning Repeatable Fluctuation of Input Signal

    NASA Astrophysics Data System (ADS)

    Ono, Hiroyuki

    This paper describes a high frequency PLL (Phase Locked Loop) synthesizer with a function of learning then eliminating repeatable fluctuation of timing intervals on series input pulses. Typical spindle encoder generates digital pulses according to the revolution speed. The intervals of each pulse have repeatable fluctuation every revolution by eccentricity or warpage of the encoder scale disk. This method provides a programmable counter for the loop counter of PLL circuit and an interval counter with memory in order to learn the repeatable fluctuation. After the learning process, the PLL generates very pure tone clock signal based on the real flutter components of the spindle revolution speed without influenced by encoder errors. This method has been applied to a hard disk test system in order to generate 3GHz read/write clock.

  4. Progress towards realization of a Quantum Matter Synthesizer

    NASA Astrophysics Data System (ADS)

    Downs, Gustaf; Trisnadi, Jonathan; Chin, Cheng

    2016-05-01

    We present our recent progress towards building a new type of optical lattice experiment. Once completed, the Quantum Matter Synthesizer (QMS) will be able to load atoms into a far-detuned lattice projected through a high numerical aperture objective lens, image the atomic distribution and cool the atoms to the vibrational ground state, and then dynamically turn off and rearrange lattice sites to achieve the desired filling fraction and spin order. We will achieve this dynamically re-arrangeable lattice by forming our 2D optical potential with Digital Micromirror Devices (DMD). Here we report the performance of our MOT and initial dRSC, our scheme for transporting atoms from our chamber into our high-resolution imaging glass cell, and our structural design for stabilizing and isolating critical optical components near the glass cell as well as science goals.

  5. All-digital radar architecture

    NASA Astrophysics Data System (ADS)

    Molchanov, Pavlo A.

    2014-10-01

    All digital radar architecture requires exclude mechanical scan system. The phase antenna array is necessarily large because the array elements must be co-located with very precise dimensions and will need high accuracy phase processing system for aggregate and distribute T/R modules data to/from antenna elements. Even phase array cannot provide wide field of view. New nature inspired all digital radar architecture proposed. The fly's eye consists of multiple angularly spaced sensors giving the fly simultaneously thee wide-area visual coverage it needs to detect and avoid the threats around him. Fly eye radar antenna array consist multiple directional antennas loose distributed along perimeter of ground vehicle or aircraft and coupled with receiving/transmitting front end modules connected by digital interface to central processor. Non-steering antenna array allows creating all-digital radar with extreme flexible architecture. Fly eye radar architecture provides wide possibility of digital modulation and different waveform generation. Simultaneous correlation and integration of thousands signals per second from each point of surveillance area allows not only detecting of low level signals ((low profile targets), but help to recognize and classify signals (targets) by using diversity signals, polarization modulation and intelligent processing. Proposed all digital radar architecture with distributed directional antenna array can provide a 3D space vector to the jammer by verification direction of arrival for signals sources and as result jam/spoof protection not only for radar systems, but for communication systems and any navigation constellation system, for both encrypted or unencrypted signals, for not limited number or close positioned jammers.

  6. Digital photorefraction

    NASA Astrophysics Data System (ADS)

    Costa, Manuel F. M.; Jorge, Jorge M.

    1998-01-01

    The early evaluation of the visual status of human infants is of a critical importance. It is of utmost importance to the development of the child's visual system that she perceives clear, focused, retinal images. Furthermore if the refractive problems are not corrected in due time amblyopia may occur. Photorefraction is a non-invasive clinical tool rather convenient for application to this kind of population. A qualitative or semi-quantitative information about refractive errors, accommodation, strabismus, amblyogenic factors and some pathologies (cataracts) can the easily obtained. The photorefraction experimental setup we established using new technological breakthroughs on the fields of imaging devices, image processing and fiber optics, allows the implementation of both the isotropic and eccentric photorefraction approaches. Essentially both methods consist on delivering a light beam into the eyes. It is refracted by the ocular media, strikes the retina, focusing or not, reflects off and is collected by a camera. The system is formed by one CCD color camera and a light source. A beam splitter in front of the camera's objective allows coaxial illumination and observation. An optomechanical system also allows eccentric illumination. The light source is a flash type one and is synchronized with the camera's image acquisition. The camera's image is digitized displayed in real time. Image processing routines are applied for image's enhancement and feature extraction.

  7. Digital photorefraction

    NASA Astrophysics Data System (ADS)

    Costa, Manuel F.; Jorge, Jorge M.

    1997-12-01

    The early evaluation of the visual status of human infants is of a critical importance. It is of utmost importance to the development of the child's visual system that she perceives clear, focused, retinal images. Furthermore if the refractive problems are not corrected in due time amblyopia may occur. Photorefraction is a non-invasive clinical tool rather convenient for application to this kind of population. A qualitative or semi-quantitative information about refractive errors, accommodation, strabismus, amblyogenic factors and some pathologies (cataracts) can the easily obtained. The photorefraction experimental setup we established using new technological breakthroughs on the fields of imaging devices, image processing and fiber optics, allows the implementation of both the isotropic and eccentric photorefraction approaches. Essentially both methods consist on delivering a light beam into the eyes. It is refracted by the ocular media, strikes the retina, focusing or not, reflects off and is collected by a camera. The system is formed by one CCD color camera and a light source. A beam splitter in front of the camera's objective allows coaxial illumination and observation. An optomechanical system also allows eccentric illumination. The light source is a flash type one and is synchronized with the camera's image acquisition. The camera's image is digitized displayed in real time. Image processing routines are applied for image's enhancement and feature extraction.

  8. Syntheses of Novel Nitrogen and Phosphorus Heterocycles.

    DTIC Science & Technology

    2014-09-26

    Chemicals and Materials Research Department, Ultrasystems, Inc. under Contract F49620-82-C-0021, "Syntheses of Novel Nitrogen and Phosphorus Hetero- * cycles ...ADl-NISS9 449 SYNTHESES OF NOVEL NITROGEN AND PHOSPHORUS HETEROCYCLES In (U) ULTRRSYSTENS INC IRVINE CR K L PRCIOREK ET RL. 26 RPR 85 SN-209?-F RFOSR...MICROCOPY RESOLUTION TEST CHART NATIONAL BURE&U OF STAOACS-963-A SR-I"I" s, -Ŕ 500 4 SYNTHESES OF NOVEL NITROGEN AND PHOSPHORUS HETEROCYCLES Contract No

  9. Endothelial cells synthesize and process apolipoprotein B.

    PubMed

    Sivaram, P; Vanni-Reyes, T; Goldberg, I J

    1996-06-21

    We reported previously that a 116-kDa lipoprotein lipase (LPL)-binding protein from endothelial cells has sequence homology to the amino-terminal region of apolipoprotein (apo) B. We now tested whether endothelial cells synthesize apoB mRNA and protein. Primers were designed to the human apoB cDNA sequence and reverse transcription polymerase chain reaction was performed using total RNA isolated from bovine and human endothelial cells. With primers to the 5' region of the apoB mRNA (amino-terminal region of apoB protein) expected size PCR products were generated from both bovine and human endothelial cells as well as from mouse liver RNA, which was used as a control. Primers designed to the 3' region of apoB mRNA generated PCR products from human endothelial cells and HepG2 cells but not from bovine or mouse cells. These data suggest that endothelial cells contain full-length apoB mRNA and that the 5' or the amino-terminal region of apoB is highly conserved from mouse to human. This was confirmed by direct sequencing of the mouse and bovine PCR products. To test whether apoB protein was produced, bovine endothelial cell proteins were metabolically labeled with [35S]methionine/cysteine or [3H]leucine and immunoprecipitated with anti-human apoB antibodies. Using extracts from cells labeled for 1 h, monoclonal antibody 47, directed to the low density lipoprotein receptor binding region of apoB, precipitated a protein of approximate molecular mass 550,000, the size of full-length apoB. Immunoprecipitation of the 550-kDa protein was abolished in the presence of added unlabeled low density lipoprotein. From cells labeled for 16 h, a 116-kDa protein was immunoprecipitated by polyclonal anti-apoB antibodies. This protein was partly released from cells by heparin treatment. Pulse-chase analysis showed that the 116-kDa fragment appeared at the same time as the full-length apoB began disappearing. The immunoprecipitated 116-kDa fragment also bound labeled LPL on ligand blot

  10. The Trajectory Synthesizer Generalized Profile Interface

    NASA Technical Reports Server (NTRS)

    Lee, Alan G.; Bouyssounouse, Xavier; Murphy, James R.

    2010-01-01

    The Trajectory Synthesizer is a software program that generates aircraft predictions for Air Traffic Management decision support tools. The Trajectory Synthesizer being used by researchers at NASA Ames Research Center was restricted in the number of trajectory types that could be generated. This limitation was not sufficient to support the rapidly changing Air Traffic Management research requirements. The Generalized Profile Interface was developed to address this issue. It provides a flexible approach to describe the constraints applied to trajectory generation and may provide a method for interoperability between trajectory generators. It also supports the request and generation of new types of trajectory profiles not possible with the previous interface to the Trajectory Synthesizer. Other enhancements allow the Trajectory Synthesizer to meet the current and future needs of Air Traffic Management research.

  11. Thermoelectric Properties of Solution Synthesized Nanostructured Materials.

    PubMed

    Finefrock, Scott W; Yang, Haoran; Fang, Haiyu; Wu, Yue

    2015-01-01

    Thermoelectric nanocomposites made by solution synthesis and compression of nanostructured chalcogenides could potentially be low-cost, scalable alternatives to traditional solid-state synthesized materials. We review the progress in this field by comparing the power factor and/or the thermoelectric figure of merit, ZT, of four classes of materials: (Bi,Sb)2(Te,Se)3, PbTe, ternary and quaternary copper chalcogenides, and silver chalcogenides. We also discuss the thermal conductivity reduction associated with multiphased nanocomposites. The ZT of the best solution synthesized materials are, in several cases, shown to be equal to or greater than the corresponding bulk materials despite the generally reduced mobility associated with solution synthesized nanocomposites. For the solution synthesized materials with the highest performance, the synthesis and processing conditions are summarized to provide guidance for future work.

  12. ORGANIC SYNTHESES USING MICROWAVES AND SUPPORTED REAGENTS

    EPA Science Inventory

    Microwave-accelerated chemical syntheses under solvent-free conditions have witnessed an explosive growth. The technique has found widespread application predominantly exploiting the inexpensive unmodified household microwave (MW) ovens although the use of dedicated MW equipment...

  13. ORGANIC SYNTHESES USING MICROWAVES AND SUPPORTED REAGENTS

    EPA Science Inventory

    Microwave-accelerated chemical syntheses under solvent-free conditions have witnessed an explosive growth. The technique has found widespread application predominantly exploiting the inexpensive unmodified household microwave (MW) ovens although the use of dedicated MW equipment...

  14. Method to synthesize metal chalcogenide monolayer nanomaterials

    SciTech Connect

    Hernandez-Sanchez, Bernadette A.; Boyle, Timothy J.

    2016-12-13

    Metal chalcogenide monolayer nanomaterials can be synthesized from metal alkoxide precursors by solution precipitation or solvothermal processing. The synthesis routes are more scalable, less complex and easier to implement than other synthesis routes.

  15. Psychoacoustic Analysis of Synthesized Jet Noise

    NASA Technical Reports Server (NTRS)

    Okcu, Selen; Rathsam, Jonathan; Rizzi, Stephen A.

    2013-01-01

    An aircraft noise synthesis capability is being developed so the annoyance caused by proposed aircraft can be assessed during the design stage. To make synthesized signals as realistic as possible, high fidelity simulation is required for source (e.g., engine noise, airframe noise), propagation and receiver effects. This psychoacoustic study tests whether the jet noise component of synthesized aircraft engine noise can be made more realistic using a low frequency oscillator (LFO) technique to simulate fluctuations in level observed in recordings. Jet noise predictions are commonly made in the frequency domain based on models of time-averaged empirical data. The synthesis process involves conversion of the frequency domain prediction into an audible pressure time history. However, because the predictions are time-invariant, the synthesized sound lacks fluctuations observed in recordings. Such fluctuations are hypothesized to be perceptually important. To introduce time-varying characteristics into jet noise synthesis, a method has been developed that modulates measured or predicted 1/3-octave band levels with a (<20Hz) LFO. The LFO characteristics are determined through analysis of laboratory jet noise recordings. For the aft emission angle, results indicate that signals synthesized using a generic LFO are perceived as more similar to recordings than those using no LFO, and signals synthesized with an angle-specific LFO are more similar to recordings than those synthesized with a generic LFO.

  16. Alumina lightweight ceramics modified with plasma synthesized nanopowders

    NASA Astrophysics Data System (ADS)

    Zake, I.; Svinka, R.; Svinka, V.; Palcevskis, E.

    2011-12-01

    The aim of this study is to clarify possibilities of using plasma synthesized Al2O3 and SiC nanopowders as additives in alumina lightweight ceramics prepared by slip casting. Each plasma synthesized nanopowder (PSNP) was incorporated in the material by a different method, because of their diverse influence on the properties of slip. Al2O3 PSNP was introduced in the matrix in form of aqueous suspension. SiC nanopowder was added directly to raw materials. Bending strength, bulk density, apparent porosity and thermal shock resistance were determined to evaluate the influence of these additives. The effect of Al2O3 PSNP addition on the properties of material depends on the initial sintering temperature. SiC particles during sintering oxidize into SiO2 and then in the reaction with alumina form mullite. Addition of SiC considerably improves bending strength and thermal shock resistance.

  17. A multi-digit tactile motion stimulator.

    PubMed

    Pei, Yu-Cheng; Lee, Tsung-Chi; Chang, Ting-Yu; Ruffatto, Donald; Spenko, Matthew; Bensmaia, Sliman

    2014-04-15

    One of the hallmarks of haptic exploration is that it typically involves movement between skin and object. Explored objects may contact multiple digits simultaneously so information about motion must be integrated across digits, a process about which little is known. To fill this gap, we have developed a stimulator that allows for the simultaneous and independent delivery of motion stimuli to multiple digits. The stimulator consists of individual units that deliver motion with three degrees of freedom: rotation (to produce motion), vertical excursion (to control depth of indentation into the skin) and arm orientation (to control the direction of motion). Each degree of freedom is controlled by a single motor. The compact design of the simulator allows for the side-by-side arrangement of the stimulator units such that they impinge upon adjacent fingers. To demonstrate the functionality of the stimulator, we performed a series of psychophysical experiments that investigate the perception of motion on multiple fingers. We find that, while the sensitivity to changes in motion direction is equivalent whether stimuli are presented to the same or to different fingers, the perceived direction of motion depends on the relative configuration of the digits. We replicated the results of previous experiments investigating motion discrimination with a single digit and were able to extend these findings by investigating motion perception across multiple digits. The novel motion stimulator will be an invaluable tool to investigate how motion information is integrated across multiple digits. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Transitioning to digital radiography.

    PubMed

    Drost, Wm Tod

    2011-04-01

    To describe the different forms of digital radiography (DR), image file formats, supporting equipment and services required for DR, storage of digital images, and teleradiology. Purchasing a DR system is a major investment for a veterinary practice. Types of DR systems include computed radiography, charge coupled devices, and direct or indirect DR. Comparison of workflow for analog and DR is presented. On the surface, switching to DR involves the purchase of DR acquisition hardware. The X-ray machine, table and grids used in analog radiography are the same for DR. Realistically, a considerable infrastructure supports the image acquisition hardware. This infrastructure includes monitors, computer workstations, a robust computer network and internet connection, a plan for storage and back up of images, and service contracts. Advantages of DR compared with analog radiography include improved image quality (when used properly), ease of use (more forgiving to the errors of radiographic technique), speed of making a complete study (important for critically ill patients), fewer repeat radiographs, less time looking for imaging studies, less physical storage space, and the ability to easily send images for consultation. With an understanding of the infrastructure requirements, capabilities and limitations of DR, an informed veterinary practice should be better able to make a sound decision about transitioning to DR. © Veterinary Emergency and Critical Care Society 2011.

  19. VCO PLL Frequency Synthesizers for Spacecraft Transponders

    NASA Technical Reports Server (NTRS)

    Smith, Scott; Mysoor, Narayan; Lux, James; Cook, Brian

    2007-01-01

    Two documents discuss a breadboard version of advanced transponders that, when fully developed, would be installed on future spacecraft to fly in deep space. These transponders will be required to be capable of operation on any deepspace- communications uplink frequency channel between 7,145 and 7,235 MHz, and any downlink frequency channel between 8,400 and 8,500 MHz. The document focuses on the design and operation of frequency synthesizers for the receiver and transmitter. Heretofore, frequency synthesizers in deep-space transponders have been based on dielectric resonator oscillators (DROs), which do not have the wide tuning bandwidth necessary to tune over all channels in the uplink or downlink frequency bands. To satisfy the requirement for tuning bandwidth, the present frequency synthesizers are based on voltage-controlled-oscillator (VCO) phase-locked loops (PLLs) implemented by use of monolithic microwave integrated circuits (MMICs) implemented using inGaP heterojunction bipolar transistor (HBT) technology. MMIC VCO PLL frequency synthesizers similar to the present ones have been used in commercial and military applications but, until now, have exhibited too much phase noise for use in deep-space transponders. The present frequency synthesizers contain advanced MMIC VCOs, which use HBT technology and have lower levels of flicker (1/f) phase noise. When these MMIC VCOs are used with high-speed MMIC frequency dividers, it becomes possible to obtain the required combination of frequency agility and low phase noise.

  20. Characterization of synthesized and treated gem diamonds

    NASA Astrophysics Data System (ADS)

    Song, Ohsung

    2007-10-01

    Synthesized diamonds have been widely employed as polishing media for precise machining and noble substrates for microelectronics. The recent development of the split sphere press has led to the commercial HPHT (high pressure high temperature) synthesis of bulk gem diamonds from graphite and to the enhancement of low quality natural diamonds. Synthesized and treated diamonds are sometimes traded deceptively as high quality natural diamonds because it is hard to distinguish among these diamonds with conventional gemological characterization methods. Therefore, we need to develop a new identification method that is non-destructive, fast, and inexpensive. We proposed using new methods of UV fluorescence and X-ray Lang topography for checking the local HPHT stress field as well as using a vibrating sample magnetometer for checking ferromagnetic residue in synthesized diamonds to distinguish these diamonds from natural ones. We observe unique differences in the local stress field images in synthesized and treated diamonds using Lang topography and UV fluorescence characterization. Our result implies that our proposed methods may be appropriate for identification of the synthesized and treated diamonds.

  1. The Artist, the Color Copier, and Digital Imaging.

    ERIC Educational Resources Information Center

    Witte, Mary Stieglitz

    The impact that color-copying technology and digital imaging have had on art, photography, and design are explored. Color copiers have provided new opportunities for direct and spontaneous image making an the potential for new transformations in art. The current generation of digital color copiers permits new directions in imaging, but the…

  2. [Digital echocardiography laboratory].

    PubMed

    Trambaiolo, Paolo; Posteraro, Alfredo; Salustri, Alessandro; Amici, Elisabetta; Piaggio, Maurizio; Decanini, Cesare; Gambelli, Giancarlo

    2004-07-01

    The implementation of a digital echocardiography laboratory exists today using the DICOM (Digital Imaging Communication in Medicine) standard to acquire, store and transfer echocardiographic digital images. The components of a laboratory include: 1) digital echocardiography machines with DICOM output, 2) a switched high-speed local area network, 3) a DICOM server with abundant local storage, and 4) a software to manage image and measurement information. The aim of this article was to describe the critical components of a digital echocardiography laboratory, discuss strategies for implementation, and describe some of the pitfalls that we encountered in our own implementation of the digital third level echocardiography laboratory.

  3. Digital communications: Microwave applications

    NASA Astrophysics Data System (ADS)

    Feher, K.

    Transmission concepts and techniques of digital systems are presented; and practical state-of-the-art implementation of digital communications systems by line-of-sight microwaves is described. Particular consideration is given to statistical methods in digital transmission systems analysis, digital modulation methods, microwave amplifiers, system gain, m-ary and QAM microwave systems, correlative techniques and applications to digital radio systems, hybrid systems, digital microwave systems design, diversity and protection switching techniques, measurement techniques, and research and development trends and unsolved problems.

  4. Digital image processing.

    PubMed

    Seeram, Euclid

    2004-01-01

    Digital image processing is now commonplace in radiology, nuclear medicine and sonography. This article outlines underlying principles and concepts of digital image processing. After completing this article, readers should be able to: List the limitations of film-based imaging. Identify major components of a digital imaging system. Describe the history and application areas of digital image processing. Discuss image representation and the fundamentals of digital image processing. Outline digital image processing techniques and processing operations used in selected imaging modalities. Explain the basic concepts and visualization tools used in 3-D and virtual reality imaging. Recognize medical imaging informatics as a new area of specialization for radiologic technologists.

  5. Digital TV processing system

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Two digital video data compression systems directly applicable to the Space Shuttle TV Communication System were described: (1) For the uplink, a low rate monochrome data compressor is used. The compression is achieved by using a motion detection technique in the Hadamard domain. To transform the variable source rate into a fixed rate, an adaptive rate buffer is provided. (2) For the downlink, a color data compressor is considered. The compression is achieved first by intra-color transformation of the original signal vector, into a vector which has lower information entropy. Then two-dimensional data compression techniques are applied to the Hadamard transformed components of this last vector. Mathematical models and data reliability analyses were also provided for the above video data compression techniques transmitted over a channel encoded Gaussian channel. It was shown that substantial gains can be achieved by the combination of video source and channel coding.

  6. Synthesize, Synthesize, Synthesize.

    ERIC Educational Resources Information Center

    Nugent, Susan Monroe, Ed.

    1987-01-01

    Focusing on synthesis--the ability to recognize and create new ideas that subsume and relate to others--as one of the most sophisticated skills writers can attain, the articles in this journal present many ideas for teaching synthesis and a number of classroom approaches that combine the study of English with other fields. The following titles and…

  7. Synthesize, Synthesize, Synthesize.

    ERIC Educational Resources Information Center

    Nugent, Susan Monroe, Ed.

    1987-01-01

    Focusing on synthesis--the ability to recognize and create new ideas that subsume and relate to others--as one of the most sophisticated skills writers can attain, the articles in this journal present many ideas for teaching synthesis and a number of classroom approaches that combine the study of English with other fields. The following titles and…

  8. A fast-settling frequency-presetting PLL frequency synthesizer with process variation compensation and spur reduction

    NASA Astrophysics Data System (ADS)

    Xiaozhou, Yan; Xiaofei, Kuang; Nanjian, Wu

    2009-04-01

    This paper proposes a fast-settling frequency-presetting PLL frequency synthesizer. A mixed-signal VCO and a digital processor are developed to accurately preset the frequency of VCO and greatly reduce the settling time. An auxiliary tuning loop is introduced in order to reduce reference spur caused by leakage current. The digital processor can automatically compensate presetting frequency variation with process and temperature, and control the operation of the auxiliary tuning loop. A 1.2 GHz integer-N synthesizer with 1 MHz reference input was implemented in a 0.18 μm process. The measured results demonstrate that the typical settling time of the synthesizer is less than 3 μs, and the phase noise is -108 dBc/Hz@ 1MHz. The reference spur is -52 dBc.

  9. Digital Control For Remote Manipulators

    NASA Technical Reports Server (NTRS)

    Bejczy, Antal K.; Dotson, Ronald S.

    1987-01-01

    Multiple microprocessors enable large separations between controllers and manipulators. Controller for remote manipulator requires no direct mechanical connection between slave arm and master arm moved by human operator. Employs two-way digital data transmission rather than mechanical linkage between master and slave. Manipulator a considerable distance from operator. Software for controller distributed between master and slave locations. Organized into modules. Hardware and software for system demonstrated in laboratory model.

  10. A Scalable High-Throughput Chemical Synthesizer

    PubMed Central

    Livesay, Eric A.; Liu, Ying-Horng; Luebke, Kevin J.; Irick, Joel; Belosludtsev, Yuri; Rayner, Simon; Balog, Robert; Johnston, Stephen Albert

    2002-01-01

    A machine that employs a novel reagent delivery technique for biomolecular synthesis has been developed. This machine separates the addressing of individual synthesis sites from the actual process of reagent delivery by using masks placed over the sites. Because of this separation, this machine is both cost-effective and scalable, and thus the time required to synthesize 384 or 1536 unique biomolecules is very nearly the same. Importantly, the mask design allows scaling of the number of synthesis sites without the addition of new valving. Physical and biological comparisons between DNA made on a commercially available synthesizer and this unit show that it produces DNA of similar quality. PMID:12466300

  11. An automated Teflon microfluidic peptide synthesizer.

    PubMed

    Zheng, Hui; Wang, Weizhi; Li, Xiaojun; Wang, Zihua; Hood, Leroy; Lausted, Christopher; Hu, Zhiyuan

    2013-09-07

    We present a microfluidic synthesizer made entirely of Teflon material for solid phase peptide synthesis (SPPS). Solvent-resistant perfluoroalkoxy (PFA) was used to construct chip-sized devices featuring multiple tri-layer pneumatic microvalves. Using these devices, model peptides were automatically synthesized and cleaved in situ in a continuous-flow manner. The total coupling and cleavage time was significantly reduced compared to conventional bulk reactors. The synthesis of a decapeptide, for instance, took less than 6 h using our device while it usually takes more than three days using conventional reactors.

  12. Digital development and morphogenesis

    PubMed Central

    Sanz-Ezquerro, JJ; Tickle, C

    2003-01-01

    Signalling interactions between the polarizing region, which produces SHH, and the apical ectodermal ridge, which produces FGFs, are essential for outgrowth and patterning of vertebrate limbs. However, mechanisms that mediate translation of early positional information of cells into anatomy remain largely unknown. In particular, the molecular and cellular basis of digit morphogenesis are not fully understood, either in terms of the formation of the different digits along the antero-posterior axis or in the way digits stop growing once pattern formation has been completed. Here we will review recent data about digit development. Manipulation of morphogenetic signals during digit formation, including application of SHH interdigitally, has shown that digit primordia possess a certain plasticity, and that digit anatomy becomes irreversibly fixed during morphogenesis. The process of generation of joints and thus segmentation and formation of digit tips is also discussed. PMID:12587920

  13. Digital rectal exam

    MedlinePlus

    ... this page: //medlineplus.gov/ency/article/007069.htm Digital rectal exam To use the sharing features on this page, please enable JavaScript. A digital rectal exam is an examination of the lower ...

  14. Optical vortex phase-shifting digital holography.

    PubMed

    Guo, Cheng-Shan; Cheng, Xin; Ren, Xiu-Yun; Ding, Jian-Ping; Wang, Hui-Tian

    2004-10-18

    We report a new optical vortex phase-shifting method for digital holography, in which an optical vortex mode is taken as the reference beam for holographic recording, and the required phase shifts are directly generated by rotating the vortex mode. In digital reconstruction, the complex amplitude of the object wave can be retrieved by use of the conventional phase shifting algorithm on condition that the digital illumination beam is replaced by an vortex beam with the same topological charge as the reference used. Both the theoretical analysis and experimental results demonstrate the feasibility of this approach.

  15. Digital holographic Michelson interferometer for nanometrology

    NASA Astrophysics Data System (ADS)

    Sevrygin, Alexander A.; Korotkov, V. I.; Pulkin, S. A.; Tursunov, I. M.; Venediktov, D. V.; Venediktov, V. Yu.; Volkov, O. V.

    2014-11-01

    The paper considers the dynamic holographic interferometry schemes with amplification (multiplication) of holographic fringes and with correction for distortions, imposed by the interferometer scheme elements. The use of digital microscope and of the matrix light modulator with direct addressing provides the completely digital closed-loop performance of the overall system for real-time evaluation of nano-scale objects size. Considered schemes were verified in the laboratory experiment, using the Michelson micro-interferometer, equipped by the USB-microscope and digital holography stage, equipped by the Holoeye spatial light modulator.

  16. CMS for digital photography: a case study

    NASA Astrophysics Data System (ADS)

    Chung, Robert Y.; Sa-areddee, Darunee

    2002-06-01

    The objectives of the study was to compare image quality from digital photography to RGB-printer under two digital imaging workflows: legacy-based and CMS-based. Due to the difference in judging criteria, the study shows that legacy- based digital imaging workflow can produce pleasing images as good as CMS-based workflow. But ICC-based CMS out performs legacy-based workflow in matching the color appearance of the source images. This is a welcome feature in direct mail catalogs whereby printed images need to match the appearance of the merchandise closely.

  17. Do Advance Directives Direct?

    PubMed

    Shapiro, Susan P

    2015-06-01

    Resolution of long-standing debates about the role and impact of advance directives - living wills and powers of attorney for health care - has been hampered by a dearth of appropriate data, in particular data that compare the process and outcomes of end-of-life decision making on behalf of patients with and without advance directives. Drawing on a large ethnographic study of patients in two intensive care units in a large urban teaching hospital, this article compares aspects of the medical decision-making process and outcomes by advance-directive status. Controlling for demographic characteristics and severity of illness, the study finds few significant differences between patients without advance directives and those who claim to have them. Surprisingly, these few differences hold only for those whose directives are in their hospital chart. There are no significant differences between those with no directive and those claiming to have a copy at home or elsewhere. The article considers the implications if directives seemingly must be in hand to show even modest effects. Do advance directives direct? The intensive care unit data provide far more support for the growing body of literature that casts doubt on their impact than studies that promote the use of them.

  18. Digital flight control actuation system study

    NASA Technical Reports Server (NTRS)

    Rossing, R.; Hupp, R.

    1974-01-01

    Flight control actuators and feedback sensors suitable for use in a redundant digital flight control system were examined. The most appropriate design approach for an advanced digital flight control actuation system for development and use in a fly-by-wire system was selected. The concept which was selected consisted of a PM torque motor direct drive. The selected system is compatible with concurrent and independent development efforts on the computer system and the control law mechanizations.

  19. Research in digital adaptive flight controllers

    NASA Technical Reports Server (NTRS)

    Kaufman, H.

    1976-01-01

    A design study of adaptive control logic suitable for implementation in modern airborne digital flight computers was conducted. Both explicit controllers which directly utilize parameter identification and implicit controllers which do not require identification were considered. Extensive analytical and simulation efforts resulted in the recommendation of two explicit digital adaptive flight controllers. Interface weighted least squares estimation procedures with control logic were developed using either optimal regulator theory or with control logic based upon single stage performance indices.

  20. Digital flight control research

    NASA Technical Reports Server (NTRS)

    Potter, J. E.; Stern, R. G.; Smith, T. B.; Sinha, P.

    1974-01-01

    The results of studies which were undertaken to contribute to the design of digital flight control systems, particularly for transport aircraft are presented. In addition to the overall design considerations for a digital flight control system, the following topics are discussed in detail: (1) aircraft attitude reference system design, (2) the digital computer configuration, (3) the design of a typical digital autopilot for transport aircraft, and (4) a hybrid flight simulator.