Direct and indirect effects of the fungicide azoxystrobin in outdoor brackish water microcosms.

PubMed

Gustafsson, Kerstin; Blidberg, Eva; Elfgren, Irene Karlsson; Hellström, Anna; Kylin, Henrik; Gorokhova, Elena

2010-02-01

The effects of the strobilurin fungicide azoxystrobin were studied in brackish water microcosms, with natural plankton communities and sediment. Two experiments were conducted: Experiment 1 (nominal conc. 0, 15 and 60 microg/L, 24-L outdoor microcosms for 21 days) and a second, follow-up, Experiment 2 (nominal conc. 0, 3, 7.5, 15 microg/L, 4-L indoor microcosms for 12 days). The microcosms represent a simplified brackish water community found in shallow semi-enclosed coastal areas in agricultural districts in the Baltic Sea region. Measured water concentrations of the fungicide (Experiment 1) were, on average, 83 and 62% of nominal concentrations directly after application, and 25 and 30% after 21 days, for the low and high dose treatments, respectively, corresponding to mean DT50-values of 15.1 and 25.8 days, for low and high dose treatments, respectively. In Experiment 1, direct toxic effects on calanoid copepods at both test concentrations were observed. Similarly, in Experiment 2, the copepod abundance was significantly reduced at all tested concentrations. There were also significant secondary effects on zooplankton and phytoplankton community structure, standing stocks and primary production. Very few ecotoxicological studies have investigated effects of plant protection products on Baltic organisms in general and effects on community structure and function specifically. Our results show that azoxystrobin is toxic to brackish water copepods at considerably lower concentrations than previously reported from single species tests on freshwater crustaceans, and that direct toxic effects on this ecologically important group may lead to cascade effects altering lower food webs and ecosystem functioning.

Soluble antigens from group B streptococci induce cytokine production in human blood cultures.

PubMed Central

von Hunolstein, C; Totolian, A; Alfarone, G; Mancuso, G; Cusumano, V; Teti, G; Orefici, G

1997-01-01

Group B streptococcal antigens stimulated tumor necrosis factor alpha (TNF-alpha), interleukin-1 (IL-1), and IL-6 production in human blood cultures in a concentration- and time-dependent fashion. The minimal concentrations of type-specific polysaccharides, lipoteichoic acid, and group-specific polysaccharide required to produce these effects were, respectively, 0.01, 1, and 10 microg/ml. Cell separation experiments indicated that monocytes were the cell type mainly responsible for cytokine production. Time course studies indicated that TNF-alpha was released before the other cytokines. TNF-alpha, however, did not appear to directly induce IL-1beta, as shown by blockade experiments with anti-TNF-alpha antibodies. IL-6 levels were moderately but significantly decreased by anti-TNF-alpha. These data indicate that several products from group B streptococci are able to directly stimulate human monocytes to release TNF-alpha, IL-1beta, and IL-6. These findings may be clinically relevant, since proinflammatory cytokines can mediate pathophysiologic changes during sepsis. PMID:9317001

Photodegradation of ibuprofen under UV-Vis irradiation: mechanism and toxicity of photolysis products.

PubMed

Li, Fu Hua; Yao, Kun; Lv, Wen Ying; Liu, Guo Guang; Chen, Ping; Huang, Hao Ping; Kang, Ya Pu

2015-04-01

The photodegradation of ibuprofen (IBP) in aqueous media was studied in this paper. The degradation mechanism, the reaction kinetics and toxicity of the photolysis products of IBP under UV-Vis irradiation were investigated by dissolved oxygen experiments, quenching experiments of reactive oxygen species (ROS), and toxicity evaluation utilizing Vibrio fischeri. The results demonstrated that the IBP degradation process could be fitted by the pseudo first-order kinetics model. The degradation of IBP by UV-Vis irradiation included direct photolysis and self-sensitization via ROS. The presence of dissolved oxygen inhibited the photodegradation of IBP, which indicated that direct photolysis was more rapid than the self-sensitization. The contribution rates of ·OH and (1)O2 were 21.8 % and 38.6 % in self-sensitization, respectively. Ibuprofen generated a number of intermediate products that were more toxic than the base compound during photodegradation.

Probing new top physics at the LHCb experiment.

PubMed

Kagan, Alexander L; Kamenik, Jernej F; Perez, Gilad; Stone, Sheldon

2011-08-19

We suggest that top quark physics can be studied at the LHCb experiment and that top quark production could be observed. Since LHCb covers a large pseudorapidity region in the forward direction, it has unique abilities to probe new physics in the top quark sector. Furthermore, we demonstrate that LHCb may be able to measure a t ̄t production rate asymmetry and, thus, indirectly probe an anomalous forward-backward t ̄t asymmetry in the forward region, a possibility suggested by the enhanced forward-backward asymmetry reported by the CDF experiment. © 2011 American Physical Society

Grassland responses to increased rainfall depend on the timescale of forcing.

PubMed

Sullivan, Martin J P; Thomsen, Meredith A; Suttle, K B

2016-04-01

Forecasting impacts of future climate change is an important challenge to biologists, both for understanding the consequences of different emissions trajectories and for developing adaptation measures that will minimize biodiversity loss. Existing variation provides a window into the effects of climate on species and ecosystems, but in many places does not encompass the levels or timeframes of forcing expected under directional climatic change. Experiments help us to fill in these uncertainties, simulating directional shifts to examine outcomes of new levels and sustained changes in conditions. Here, we explore the translation between short-term responses to climate variability and longer-term trajectories that emerge under directional climatic change. In a decade-long experiment, we compare effects of short-term and long-term forcings across three trophic levels in grassland plots subjected to natural and experimental variation in precipitation. For some biological responses (plant productivity), responses to long-term extension of the rainy season were consistent with short-term responses, while for others (plant species richness, abundance of invertebrate herbivores and predators), there was pronounced divergence of long-term trajectories from short-term responses. These differences between biological responses mean that sustained directional changes in climate can restructure ecological relationships characterizing a system. Importantly, a positive relationship between plant diversity and productivity turned negative under one scenario of climate change, with a similar change in the relationship between plant productivity and consumer biomass. Inferences from experiments such as this form an important part of wider efforts to understand the complexities of climate change responses. © 2016 John Wiley & Sons Ltd.

Characterizing the sources, range, and environmental influences of radon 222 and its decay products

NASA Astrophysics Data System (ADS)

Nero, A. V.; Sextro, R. G.; Doyle, S. M.; Moed, B. A.; Nazaroff, W. W.; Revzan, K. L.; Schwehr, M. B.

1985-06-01

Recent results from our group directly assist efforts to identify and control excessive concentrations of radon 222 and its decay products in residential environments. We have demonstrated directly the importance of pressure-induced flow of soil gas for transport of radon from the ground into houses. Analysis of available information from measurements of concentration in US homes has resulted in a quantitative appreciation of the distribution of indoor levels, including the degree of dependence on geographic location. Experiments on the effectiveness of air cleaning devices for removal of particles and radon decay products indicate the potential and limitations of this approach to control.

It's Not Just the "Heavy NP": Relative Phrase Length Modulates the Production of Heavy-NP Shift

ERIC Educational Resources Information Center

Stallings, Lynne M.; MacDonald, Maryellen C.

2011-01-01

Heavy-NP shift is the tendency for speakers to place long direct object phrases at the end of a clause rather than next to the verb. Though some analyses have focused on length of the direct object phrase alone, results from two experiments demonstrate that the length of the direct object relative to that of other phrases, and not the length of…

Goal-directed visual attention drives health goal priming: An eye-tracking experiment.

PubMed

van der Laan, Laura N; Papies, Esther K; Hooge, Ignace T C; Smeets, Paul A M

2017-01-01

Several lab and field experiments have shown that goal priming interventions can be highly effective in promoting healthy food choices. Less is known, however, about the mechanisms by which goal priming affects food choice. This experiment tested the hypothesis that goal priming affects food choices through changes in visual attention. Specifically, it was hypothesized that priming with the dieting goal steers attention toward goal-relevant, low energy food products, which, in turn, increases the likelihood of choosing these products. In this eye-tracking experiment, 125 participants chose between high and low energy food products in a realistic online supermarket task while their eye movements were recorded with an eye-tracker. One group was primed with a health and dieting goal, a second group was exposed to a control prime, and a third group was exposed to no prime at all. The health goal prime increased low energy food choices and decreased high energy food choices. Furthermore, the health goal prime resulted in proportionally longer total dwell times on low energy food products, and this effect mediated the goal priming effect on choices. The findings suggest that the effect of priming on consumer choice may originate from an increase in attention for prime-congruent items. This study supports the effectiveness of health goal priming interventions in promoting healthy eating and opens up directions for research on other behavioral interventions that steer attention toward healthy foods. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

[Photodegradation of naproxen in aqueous systems by UV irradiation: mechanism and toxicity of photolysis products].

PubMed

Ma, Du-juan; Liu, Guo-guang; Lü, Wen-ying; Yao, Kun; Zhou, Li-hua; Xie, Cheng-ping

2013-05-01

This paper studies the degradation mechanism, the reaction kinetics and the toxicity of photolysis products of naproxen in waters under UV irradiation (120 W mercury lamp) by quenching experiments of reactive oxygen species (ROS), oxygen concentration experiment and toxicity evaluation using Vibrio fischeri bacteria. The results demonstrated that NPX could be degraded effectively by UV irradiation and the photolysis pathways was the sum of the degradation by direct photolysis and self-sensitization via ROS, and the contribution rates of self-sensitized photodegradation were 0.1%, 80.2%, 35.7% via *OH, (1)O2, O2*-, respectively. The effect of oxygen concentration illustrated that dissolved oxygen had an inhibitory effect on the direct photodegradation of NPX, and the higher the oxygen content, the more obvious the inhibitory effect. The toxicity evaluation illustrated the formation of some intermediate products that were more toxic than NPX during the photodegradation of NPX. The process of NPX degradation in all cases could be fitted by the pseudo first-order kinetics model.

The use of community herbal monographs to facilitate registrations and authorisations of herbal medicinal products in the European Union 2004-2012.

PubMed

Peschel, Wieland

2014-12-02

The provisions for the simplified registration of traditional herbal medicinal products in the European Union were introduced by Directive 2004/24/EC amending Directive 2001/83/EC (Chapter 2a) in 2004. Since implementation in the European member states until December 2012 a total of 1015 registrations (traditional use) and 514 authorisations (well-established use) have been granted for products containing substances/ preparations from about 200 different herbal drugs. The overall number of received applications with more than one third still under assessment suggests a further increase for the next years. This review summarises the main features of registered and authorised herbal medicinal products in the EU and evaluates available data against provisions of Directive 2004/24/EC and European standards established by the Committee on Herbal Medicinal Products at the European Medicines Agency. The supportive function of Community herbal monographs is described as regards availability and their use in national procedures, which is complemented by an analysis of specific future challenges from experiences made with the implementation of Directive 2004/24/EC so far. Copyright © 2014. Published by Elsevier Ireland Ltd.

Mario Becomes Cognitive.

PubMed

Schrodt, Fabian; Kneissler, Jan; Ehrenfeld, Stephan; Butz, Martin V

2017-04-01

In line with Allen Newell's challenge to develop complete cognitive architectures, and motivated by a recent proposal for a unifying subsymbolic computational theory of cognition, we introduce the cognitive control architecture SEMLINCS. SEMLINCS models the development of an embodied cognitive agent that learns discrete production rule-like structures from its own, autonomously gathered, continuous sensorimotor experiences. Moreover, the agent uses the developing knowledge to plan and control environmental interactions in a versatile, goal-directed, and self-motivated manner. Thus, in contrast to several well-known symbolic cognitive architectures, SEMLINCS is not provided with production rules and the involved symbols, but it learns them. In this paper, the actual implementation of SEMLINCS causes learning and self-motivated, autonomous behavioral control of the game figure Mario in a clone of the computer game Super Mario Bros. Our evaluations highlight the successful development of behavioral versatility as well as the learning of suitable production rules and the involved symbols from sensorimotor experiences. Moreover, knowledge- and motivation-dependent individualizations of the agents' behavioral tendencies are shown. Finally, interaction sequences can be planned on the sensorimotor-grounded production rule level. Current limitations directly point toward the need for several further enhancements, which may be integrated into SEMLINCS in the near future. Overall, SEMLINCS may be viewed as an architecture that allows the functional and computational modeling of embodied cognitive development, whereby the current main focus lies on the development of production rules from sensorimotor experiences. Copyright © 2017 Cognitive Science Society, Inc.

Electrosynthesis Technology.

ERIC Educational Resources Information Center

Weinberg, Norman L.

1983-01-01

Provides a prospective on electrosynthesis technology for chemical educators and students by discussing electrosynthesis reactions and experiments. Includes tables illustrating some electrochemical products, variables to consider in electrochemical reactions, indirect electrolysis of organic compounds, examples of direct/indirect electrochemical…

30 CFR 48.27 - Training of miners assigned to a task in which they have had no previous experience; minimum...

Code of Federal Regulations, 2012 CFR

2012-07-01

..., drilling machine operators, haulage and conveyor systems operators, ground control machine operators, AMS... practice in the assigned tasks, and the performance of work duties at times or places where production is..., while under direct and immediate supervision and production is in progress, operation of the machine or...

30 CFR 48.27 - Training of miners assigned to a task in which they have had no previous experience; minimum...

Code of Federal Regulations, 2011 CFR

2011-07-01

..., drilling machine operators, haulage and conveyor systems operators, ground control machine operators, AMS... practice in the assigned tasks, and the performance of work duties at times or places where production is..., while under direct and immediate supervision and production is in progress, operation of the machine or...

30 CFR 48.27 - Training of miners assigned to a task in which they have had no previous experience; minimum...

Code of Federal Regulations, 2014 CFR

2014-07-01

..., drilling machine operators, haulage and conveyor systems operators, ground control machine operators, AMS... practice in the assigned tasks, and the performance of work duties at times or places where production is..., while under direct and immediate supervision and production is in progress, operation of the machine or...

30 CFR 48.27 - Training of miners assigned to a task in which they have had no previous experience; minimum...

Code of Federal Regulations, 2013 CFR

2013-07-01

..., drilling machine operators, haulage and conveyor systems operators, ground control machine operators, AMS... practice in the assigned tasks, and the performance of work duties at times or places where production is..., while under direct and immediate supervision and production is in progress, operation of the machine or...

Two-plasmon decay mitigation in direct-drive inertial-confinement-fusion experiments using multilayer targets

DOE PAGES

Follett, R. K.; Delettrez, J. A.; Edgell, D. H.; ...

2016-04-15

Multilayer direct-drive inertial-confinement-fusion (ICF) targets are shown to significantly reduce two-plasmon-decay (TPD) driven hot-electron production while maintaining high hydrodynamic efficiency. Implosion experiments on the OMEGA Laser used targets with silicon layered between an inner beryllium and outer silicon-doped plastic ablator. A factor of five reduction in hot-electron generation (> 50 keV) was observed in the multilayer targets relative to pure CH targets. Three-dimensional simulations of the TPD driven hot-electron production using a laser-plasma interaction code (LPSE) that includes nonlinear and kinetic effects show excellent agreement with the measurements. As a result, the simulations suggest that the reduction in hot-electron productionmore » observed in the multilayer targets is primarily due to increased electron-ion collisional damping.« less

Human health safety evaluation of cosmetics in the EU: a legally imposed challenge to science.

PubMed

Pauwels, M; Rogiers, V

2010-03-01

As stated in the European legislation, cosmetic products present on the European market must be safe for the consumer. Safety evaluation of the products is carried out by a qualified safety assessor who needs to consider potential exposure scenarios next to the physicochemical and toxicological profiles of all composing ingredients. Whereas, until recently, the tools to determine the toxicological profile of cosmetic ingredients mainly consisted of animal experiments, they have now been narrowed down substantially by the legally imposed animal testing ban on cosmetic ingredients, taken up in the Cosmetic Products Directive (76/768/EEC). This Directive, however, is not a stand-alone piece of European legislation, since as well directly as indirectly it is influenced by a complex web of related legislations. Vertical legislations deal with different categories of chemicals, including dangerous substances, biocides, plant protection products, food additives, medicinal products, and of course also cosmetics. Horizontal legislative texts, on the contrary, cover more general fields such as protection of experimental animals, consumer product safety, misleading of consumers, specific provisions for aerosols, and others. Experience has learnt that having a general overview of these related legislations is necessary to understand their impact on the cosmetic world in general terms and on cosmetic safety evaluation in particular. This goes for a variety of concerned parties, including national and European regulators/agencies, contract laboratories, raw material suppliers, cosmetic companies, research and educational centers. They all deal with a number of aspects important for the quality and toxicity of cosmetics and their ingredients. This review summarises the most relevant points of the legislative texts of different types of product categories and emphasises their impact on the safety evaluation of cosmetics.

Human health safety evaluation of cosmetics in the EU: A legally imposed challenge to science

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pauwels, M., E-mail: Marleen.Pauwels@vub.ac.b; Rogiers, V.

As stated in the European legislation, cosmetic products present on the European market must be safe for the consumer. Safety evaluation of the products is carried out by a qualified safety assessor who needs to consider potential exposure scenarios next to the physicochemical and toxicological profiles of all composing ingredients. Whereas, until recently, the tools to determine the toxicological profile of cosmetic ingredients mainly consisted of animal experiments, they have now been narrowed down substantially by the legally imposed animal testing ban on cosmetic ingredients, taken up in the Cosmetic Products Directive (76/768/EEC). This Directive, however, is not a stand-alonemore » piece of European legislation, since as well directly as indirectly it is influenced by a complex web of related legislations. Vertical legislations deal with different categories of chemicals, including dangerous substances, biocides, plant protection products, food additives, medicinal products, and of course also cosmetics. Horizontal legislative texts, on the contrary, cover more general fields such as protection of experimental animals, consumer product safety, misleading of consumers, specific provisions for aerosols, and others. Experience has learnt that having a general overview of these related legislations is necessary to understand their impact on the cosmetic world in general terms and on cosmetic safety evaluation in particular. This goes for a variety of concerned parties, including national and European regulators/agencies, contract laboratories, raw material suppliers, cosmetic companies, research and educational centers. They all deal with a number of aspects important for the quality and toxicity of cosmetics and their ingredients. This review summarises the most relevant points of the legislative texts of different types of product categories and emphasises their impact on the safety evaluation of cosmetics.« less

A systematic literature review of Releasing Time to Care: The Productive Ward.

PubMed

Wright, Stella; McSherry, Wilfred

2013-05-01

This systematic review provides an overview of the literature published on Releasing Time to Care: The Productive Ward between 2005 and June 2011. Releasing Time to Care: The Productive Ward programme was developed by the NHS Institute for Innovation and Improvement and launched in England in 2007. The programme comprises thirteen modules that aim to increase time for direct patient care, improve the patient and staff experience and make changes to the ward environment to improve efficiency. A systematic literature review. The terms 'Releasing Time to Care' and 'Productive Ward' were applied to key healthcare databases; CINAHL, Medline, Science Direct, ProQuest, Health Business Elite, British Nursing Index, Embase, Health Management Information Consortium and PsychInfo. All papers were read and subject to a quality assessment. The literature search identified 95 unique sources. A lack of research on The Productive Ward programme meant it was necessary to include non-empirical literature. In total, 18 articles met the inclusion criteria. Seven key themes were identified: the patient and staff experience, direct care time, patient safety, financial impact, embedding and sustainability, executive support and leadership, and common barriers and determinants of success. It also highlighted areas that require further exploration such as long-term sustainability of the programme and consistent data measurement between organisations. The review tentatively reports how The Productive Ward programme has been used to transform nursing practice for the benefit of patients and frontline staff, and how it resulted in cost savings. The literature review identified a potential positive results bias in the current literature whereby favourable outcomes were reported. This paper summarises the types of evidence and current literature on The Productive Ward providing a reference for frontline staff implementing the programme. © 2013 Blackwell Publishing Ltd.

Linking product design to consumer behavior: the moderating role of consumption experience.

PubMed

Gilal, Naeem Gul; Zhang, Jing; Gilal, Faheem Gul

2018-01-01

Previous investigations of product design broadly link aesthetic, functional, and symbolic designs to sales growth, high turnover, and market share. However, the effect of product design dimensions on consumer willingness-to-buy (WTB) and word-of-mouth (WOM) is virtually ignored by consumer researchers. Similarly, whether the consumption experience can differentiate the effect of the three product design dimensions on WTB and WOM is completely unknown. Using categorization theory as a lens, our study aims to explore the effect of product design dimensions on consumer WTB and WOM directly and indirectly through the moderation of the consumption experience. A convenience sample of (n=357) Chinese and (n=277) Korean shoppers was utilized to test the hypotheses in the fashion apparel industry. Our results showed that the aesthetic design was more prominent in capturing consumer WTB for both Chinese and Koreans. Similarly, the aesthetic design was more salient in enhancing WOM for Chinese, whereas the symbolic design was more promising in terms of improving WOM for Koreans. Further, our moderation results demonstrated that the consumption experience could differentiate the effects of the three product design dimensions on consumer WTB and WOM for Chinese. By contrast, the consumption experience could only interact with the aesthetic design to improve WOM for South Koreans. To the best of authors' knowledge, the present study is one of the initial attempts to link three product design dimensions with consumer WTB and WOM in the fashion apparel context and explored whether consumption experience competes or complement with three product design dimensions to shape consumer WTB and WOM for Chinese and Koreans.

Inflectional instabilities in the wall region of bounded turbulent shear flows

NASA Technical Reports Server (NTRS)

Swearingen, Jerry D.; Blackwelder, Ron F.; Spalart, Philippe R.

1987-01-01

The primary thrust of this research was to identify one or more mechanisms responsible for strong turbulence production events in the wall region of bounded turbulent shear flows. Based upon previous work in a transitional boundary layer, it seemed highly probable that the production events were preceded by an inflectional velocity profile which formed on the interface between the low-speed streak and the surrounding fluid. In bounded transitional flows, this unstable profile developed velocity fluctuations in the streamwise direction and in the direction perpendicular to the sheared surface. The rapid growth of these instabilities leads to a breakdown and production of turbulence. Since bounded turbulent flows have many of the same characteristics, they may also experience a similar type of breakdown and turbulence production mechanism.

Oxygen and iron production by electrolytic smelting of lunar soil

NASA Technical Reports Server (NTRS)

Colson, R. O.; Haskin, L. A.

1992-01-01

Work during the past year involved two aspects: (1) electrolysis experiments on a larger scale than done before, and (2) collaboration with Carbotek Inc. on design for a lunar magma electrolysis cell. It was demonstrated previously that oxygen can be produced by direct electrolysis of silicate melts. Previous experiments using 50-100 mg of melt have succeeded in measuring melt resistivities, oxygen production efficiencies, and have identified the character of metal products. A series of experiments using 1-8 grams of silicate melt, done in alumina and spinel containers sufficiently large that surface tension effects between the melt and the wall are expected to have minor effect on the behavior of the melt in the region of the electrodes were completed. The purpose of these experiments was to demonstrate the durability of the electrode and container materials, demonstrate the energy efficiency of the electrolysis process, further characterize the nature of the expected metal and spinel products, measure the efficiency of oxygen production and compare to that predicted on the basis of the smaller-scale experiments, and identify any unexpected benefits or problems of the process. Four experimental designs were employed. Detailed results of these experiments are given in the appendix ('Summary of scaling-up experiments'); a general report of the results is given in terms of implications of the experiments on container materials, cathode materials, anode materials, bubble formation and frothing of the melt, cell potential, anode-cathode distance, oxygen efficiency, and energy efficiency.

Moving from the Classroom to the Workplace: A Service-Learning Case Study of a Media Production Capstone Course

ERIC Educational Resources Information Center

Giese, Mark

2013-01-01

This is a case study of how a capstone course, Producing and Directing, evolved into a service-learning course designed to provide graduating students with real-world workplace experience. It will examine issues including course structure, grading issues, course and client logistics, unaddressed skill sets, group work, and work-product quality…

Experience Effect in E-Learning Research

NASA Astrophysics Data System (ADS)

Wu, Bing; Xu, WenXia; Ge, Jun

This study is a productivity review on the literature gleaned from SSCI, SCIE databases concerning experience in E-Learning research. The result indicates that the number of literature productions on experience effect in ELearning research is still growing from 2005. The main research development country is Croatia, and from the analysis of the publication year, the number of papers is increasing to the peaking in 2010. And the main source title is British Journal of Educational Technology. In addition the subject area concentrated on Education & Educational Research. Moreover the research focuses on are mainly survey research and empirical research, in order to explore experience effect in E-Learning research. Also the limitations and future research of these research were discussed, so that the direction for further research work can be exploited

SOE for the Future.

ERIC Educational Resources Information Center

Briers, Gary E.; And Others

1989-01-01

Eight articles in this this theme issue explore aspects of supervised occupational experience (SOE) in agriculture: definitions, new directions, the value of SOE, experiential learning, the science of agriculture, production agriculture, hydroponic technology, and Future Farmers of America proficiency awards. (SK)

Trophic Tangles through Time? Opposing Direct and Indirect Effects of an Invasive Omnivore on Stream Ecosystem Processes

PubMed Central

Moore, Jonathan W.; Carlson, Stephanie M.; Twardochleb, Laura A.; Hwan, Jason L.; Fox, Justin M.; Hayes, Sean A.

2012-01-01

Omnivores can impact ecosystems via opposing direct or indirect effects. For example, omnivores that feed on herbivores and plants could either increase plant biomass due to the removal of herbivores or decrease plant biomass due to direct consumption. Thus, empirical quantification of the relative importance of direct and indirect impacts of omnivores is needed, especially the impacts of invasive omnivores. Here we investigated how an invasive omnivore (signal crayfish, Pacifastacus leniusculus) impacts stream ecosystems. First, we performed a large-scale experiment to examine the short-term (three month) direct and indirect impacts of crayfish on a stream food web. Second, we performed a comparative study of un-invaded areas and areas invaded 90 years ago to examine whether patterns from the experiment scaled up to longer time frames. In the experiment, crayfish increased leaf litter breakdown rate, decreased the abundance and biomass of other benthic invertebrates, and increased algal production. Thus, crayfish controlled detritus via direct consumption and likely drove a trophic cascade through predation on grazers. Consistent with the experiment, the comparative study also found that benthic invertebrate biomass decreased with crayfish. However, contrary to the experiment, crayfish presence was not significantly associated with higher leaf litter breakdown in the comparative study. We posit that during invasion, generalist crayfish replace the more specialized native detritivores (caddisflies), thereby leading to little long-term change in net detrital breakdown. A feeding experiment revealed that these native detritivores and the crayfish were both effective consumers of detritus. Thus, the impacts of omnivores represent a temporally-shifting interplay between direct and indirect effects that can control basal resources. PMID:23209810

Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci.

PubMed

Stepanović, Srdjan; Vuković, Dragana; Hola, Veronika; Di Bonaventura, Giovanni; Djukić, Slobodanka; Cirković, Ivana; Ruzicka, Filip

2007-08-01

The details of all steps involved in the quantification of biofilm formation in microtiter plates are described. The presented protocol incorporates information on assessment of biofilm production by staphylococci, gained both by direct experience as well as by analysis of methods for assaying biofilm production. The obtained results should simplify quantification of biofilm formation in microtiter plates, and make it more reliable and comparable among different laboratories.

Knowledge about writing influences reading: Dynamic visual information about letter production facilitates letter identification.

PubMed

Schubert, Teresa; Reilhac, Caroline; McCloskey, Michael

2018-06-01

How are reading and writing related? In this study, we address the relationship between letter identification and letter production, uncovering a link in which production information can be used to identify letters presented dynamically. By testing an individual with a deficit in letter identification, we identified a benefit which would be masked by ceiling effects in unimpaired readers. In Experiment 1 we found that letter stimuli defined by the direction of dot motion (tiny dots within letter move leftward, background dots move rightward) provided no advantage over static letters. In Experiment 2, we tested dynamic stimuli in which the letter shapes emerged over time: drawn as they would be written, drawn in reverse, or with the letter shape filled in randomly. Improved identification was observed only for letters drawn as they are typically written. These results demonstrate that information about letter production can be integrated into letter identification, and point to bi-directional connections between stored letter production information (used for writing) and abstract letter identity representations (used in both reading and writing). The links from stored production information to abstract letter identities allow the former to activate the latter. We also consider the implications of our results for remediation of acquired letter identification deficits, including letter-drawing treatments and the underlying cause of their efficacy. Copyright © 2018 Elsevier Ltd. All rights reserved.

Earth Radiation Budget Experiment (ERBE) validation

NASA Technical Reports Server (NTRS)

Barkstrom, Bruce R.; Harrison, Edwin F.; Smith, G. Louis; Green, Richard N.; Kibler, James F.; Cess, Robert D.

1990-01-01

During the past 4 years, data from the Earth Radiation Budget Experiment (ERBE) have been undergoing detailed examination. There is no direct source of groundtruth for the radiation budget. Thus, this validation effort has had to rely heavily upon intercomparisons between different types of measurements. The ERBE SCIENCE Team chose 10 measures of agreement as validation criteria. Late in August 1988, the Team agreed that the data met these conditions. As a result, the final, monthly averaged data products are being archived. These products, their validation, and some results for January 1986 are described. Information is provided on obtaining the data from the archive.

Evidence for age-related changes to temporal attention and memory from the choice time production task

PubMed Central

Gooch, Cynthia M.; Stern, Yaakov; Rakitin, Brian C.

2009-01-01

The effect of aging on interval timing was examined using a choice time production task, which required participants to choose a key response based on the location of the stimulus, but to delay responding until after a learned time interval. Experiment 1 varied attentional demands of the response choice portion of the task by varying difficulty of stimulus-response mapping. Choice difficulty affected temporal accuracy equally in both age groups, but older participants’ response latencies were more variable under more difficult response choice conditions. Experiment 2 tested the contribution of long-term memory to differences in choice time production between age groups over 3 days of testing. Direction of errors in time production between the two age groups diverged over the 3 sessions, but variability did not differ. Results from each experiment separately show age-related changes to attention and memory in temporal processing using different measures and manipulations in the same task. PMID:19132578

Neutrino Flux Prediction for the NuMI Beamline

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soplin, Leonidas Aliaga

2016-01-01

The determination of the neutrino flux in any conventional neutrino beam presents a challenge for the current and future short and long baseline neutrino experiments. The uncertainties associated with the production and attenuation of the hadrons in the beamline materials along with those associated with the beam optics have a big effect in the flux spectrum knowledge. For experiments like MINERvA, understanding the flux is crucial since it enters directly into every neutrino-nucleus cross-sections measurements. The foundation of this work is predicting the neutrino flux at MINERvA using dedicated measurements of hadron production in hadron-nucleus collisions and incorporating in-situ MINERvAmore » data that can provide additional constraints. This work also includes the prospect for predicting the flux at other detectors like the NOvA Near detector. The procedure and conclusions of this thesis will have a big impact on future hadron production experiments and on determining the flux for the upcoming DUNE experiment.« less

Neutrino Flux Prediction for the NuMI Beamline

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aliaga Soplin, Leonidas

2016-01-01

The determination of the neutrino flux in any conventional neutrino beam presents a challenge for the current and future short and long baseline neutrino experiments. The uncertainties associated with the production and attenuation of the hadrons in the beamline materials along with those associated with the beam optics have a big effect in the flux spectrum knowledge. For experiments like MINERvA, understanding the flux is crucial since it enters directly into every neutrino-nucleus cross-sections measurements. The foundation of this work is predicting the neutrino flux at MINERvA using dedicated measurements of hadron production in hadron-nucleus collisions and incorporating in-situ MINERvAmore » data that can provide additional constraints. This work also includes the prospect for predicting the flux at other detectors like the NOvA Near detector. The procedure and conclusions of this thesis will have a big impact on future hadron production experiments and on determining the fl ux for the upcoming DUNE experiment.« less

Linking product design to consumer behavior: the moderating role of consumption experience

PubMed Central

Gilal, Naeem Gul; Zhang, Jing; Gilal, Faheem Gul

2018-01-01

Background Previous investigations of product design broadly link aesthetic, functional, and symbolic designs to sales growth, high turnover, and market share. However, the effect of product design dimensions on consumer willingness-to-buy (WTB) and word-of-mouth (WOM) is virtually ignored by consumer researchers. Similarly, whether the consumption experience can differentiate the effect of the three product design dimensions on WTB and WOM is completely unknown. Using categorization theory as a lens, our study aims to explore the effect of product design dimensions on consumer WTB and WOM directly and indirectly through the moderation of the consumption experience. Methods A convenience sample of (n=357) Chinese and (n=277) Korean shoppers was utilized to test the hypotheses in the fashion apparel industry. Results Our results showed that the aesthetic design was more prominent in capturing consumer WTB for both Chinese and Koreans. Similarly, the aesthetic design was more salient in enhancing WOM for Chinese, whereas the symbolic design was more promising in terms of improving WOM for Koreans. Further, our moderation results demonstrated that the consumption experience could differentiate the effects of the three product design dimensions on consumer WTB and WOM for Chinese. By contrast, the consumption experience could only interact with the aesthetic design to improve WOM for South Koreans. Conclusion To the best of authors’ knowledge, the present study is one of the initial attempts to link three product design dimensions with consumer WTB and WOM in the fashion apparel context and explored whether consumption experience competes or complement with three product design dimensions to shape consumer WTB and WOM for Chinese and Koreans. PMID:29785145

Direct enzymatic bioelectrocatalysis: differentiating between myth and reality

PubMed Central

2017-01-01

Enzymatic bioelectrocatalysis is being increasingly exploited to better understand oxidoreductase enzymes, to develop minimalistic yet specific biosensor platforms, and to develop alternative energy conversion devices and bioelectrosynthetic devices for the production of energy and/or important chemical commodities. In some cases, these enzymes are able to electronically communicate with an appropriately designed electrode surface without the requirement of an electron mediator to shuttle electrons between the enzyme and electrode. This phenomenon has been termed direct electron transfer or direct bioelectrocatalysis. While many thorough studies have extensively investigated this fascinating feat, it is sometimes difficult to differentiate desirable enzymatic bioelectrocatalysis from electrocatalysis deriving from inactivated enzyme that may have also released its catalytic cofactor. This article will review direct bioelectrocatalysis of several oxidoreductases, with an emphasis on experiments that provide support for direct bioelectrocatalysis versus denatured enzyme or dissociated cofactor. Finally, this review will conclude with a series of proposed control experiments that could be adopted to discern successful direct electronic communication of an enzyme from its denatured counterpart. PMID:28637918

Explicit and implicit attitude toward an emerging food technology: The case of cultured meat.

PubMed

Bekker, Gerben A; Fischer, Arnout R H; Tobi, Hilde; van Trijp, Hans C M

2017-01-01

Cultured meat is an unfamiliar emerging food technology that could provide a near endless supply of high quality protein with a relatively small ecological footprint. To understand consumer acceptance of cultured meat, this study investigated the influence of information provision on the explicit and implicit attitude toward cultured meat. Three experiments were conducted using a Solomon four-group design to rule out pretest sensitization effects. The first experiment (N = 190) showed that positive or negative information about cultured meat changed the explicit attitude in the direction of the information. This effect was smaller for participants who were more familiar with cultured meat. In the second experiment (N = 194) positive information was provided about solar panels, an attitude object belonging to the same sustainable product category as sustainable food products such as cultured meat. Positive information about solar panels was found to change the explicit attitude in the direction of the information. Using mood induction, the third experiment (N = 192) ruled out the alternative explanation that explicit attitude change in experiment 1 and 2 was caused by content free affect rather than category based inferences. The implicit attitude appeared insensitive to both information or mood state in all three experiments. These findings show that the explicit attitude toward cultured meat can be influenced by information about the sustainability of cultured meat and information about a positively perceived sustainable product. This effect was shown to be content based rather than merely affect based. Content based information in a relevant context could therefore contribute to the commercial success of cultured meat. Copyright © 2016 Elsevier Ltd. All rights reserved.

Profiling the Shopping Behavior of Elderly Consumers.

ERIC Educational Resources Information Center

Mason, J. Barry; Bearden, William O.

1978-01-01

Data were collected by personal interview on shopping roles, information processing, food stamp and coupon use, store brand purchases, mispricing and product unavailability experiences, and with familiarity with fair trade practices. Implications and directions for further research are suggested. (Author)

Suggestions for planning a migration-monitoring network based on the experience of establishing and operating the maps program

Treesearch

David F. DeSante

2005-01-01

Based on the experience of creating and implementing the Monitoring Avian Productivity and Survivorship (MAPS) program, I suggest that, to be successful, a migration-monitoring network must: (1) provide strong justification for the data it proposes to collect; (2) provide direct links between those monitoring data and both research and management goals; (3) provide...

The Role of Experience in the Acquisition and Production of Diminutives and Gender in Spanish: Evidence from L2 Learners and Heritage Speakers

ERIC Educational Resources Information Center

Montrul, Silvina; de la Fuente, Israel; Davidson, Justin; Foote, Rebecca

2013-01-01

This study examined whether type of early language experience provides advantages to heritage speakers over second language (L2) learners with morphology, and investigated knowledge of gender agreement and its interaction with diminutive formation. Diminutives are a hallmark of Child Directed Speech in early language development and a highly…

Dimensional Precision Research of Wax Molding Rapid Prototyping based on Droplet Injection

NASA Astrophysics Data System (ADS)

Mingji, Huang; Geng, Wu; yan, Shan

2017-11-01

The traditional casting process is complex, the mold is essential products, mold quality directly affect the quality of the product. With the method of rapid prototyping 3D printing to produce mold prototype. The utility wax model has the advantages of high speed, low cost and complex structure. Using the orthogonal experiment as the main method, analysis each factors of size precision. The purpose is to obtain the optimal process parameters, to improve the dimensional accuracy of production based on droplet injection molding.

Cytokines and immune surveillance in humans

NASA Technical Reports Server (NTRS)

Sonnenfeld, Gerald

1994-01-01

Evidence from both human and rodent studies has indicated that alterations in immunological parameters occur after space flight. Among the parameters shown, by us and others, to be affected is the production of interferons. Interferons are a family of cytokines that are antiviral and play a major role in regulating immune responses that control resistance to infection. Alterations in interferon and other cytokine production and activity could result in changes in immunity and a possible compromise of host defenses against both opportunistic and external infections. The purpose of the present study is to explore further the effects of space flight on cyotokines and cytokine-directed immunological function. Among the tests carried out are interferon-alpha production, interferon-gamma production, interleukin-1 and -2 production, signal transduction in neutrophils, signal transduction in monocytes, and monocyte phagocytic activity. The experiments will be performed using peripheral blood obtained from human subjects. It is our intent to eventually carry out these experiments using astronauts as subjects to determine the effects of space flight on cytokine production and activity. However, these subjects are not currently available. Until they become available, we will carry out these experiments using subjects maintained in the bed-rest model for microgravity.

Direct electron-pair production by high energy heavy charged particles

NASA Technical Reports Server (NTRS)

Takahashi, Y.; Gregory, J. C.; Hayashi, T.; Dong, B. L.

1989-01-01

Direct electron pain production via virtual photons by moving charged particles is a unique electro-magnetic process having a substantial dependence on energy. Most electro-magnetic processes, including transition radiation, cease to be sensitive to the incident energy above 10 TeV/AMU. Thus, it is expected, that upon establishment of cross section and detection efficiency of this process, it may provide a new energy measuring technique above 10 TeV/AMU. Three accelerator exposures of emulsion chambers designed for measurements of direct electron-pains were performed. The objectives of the investigation were to provide the fundamental cross-section data in emulsion stacks to find the best-fit theoretical model, and to provide a calibration of measurements of direct electron-pairs in emulsion chamber configurations. This paper reports the design of the emulsion chambers, accelerator experiments, microscope measurements, and related considerations for future improvements of the measurements, and for possible applications to high energy cosmic ray experiments. Also discussed are the results from scanning 56m of emulsion tracks at 1200x magnification so that scanning efficiency is optimized. Measurements of the delta-ray range spectrum were also performed for much shorter track lengths, but with sufficiently large statistics in the number of measured delta-rays.

Direct Measurements of 3D Structure, Chemistry and Mass Density During the Induction Period of C3S Hydration

PubMed Central

Hu, Qinang; Aboustait, Mohammed; Kim, Taehwan; Ley, M. Tyler; Bullard, Jeffrey W.; Scherer, George; Hanan, Jay C.; Rose, Volker; Winarski, Robert; Gelb, Jeffrey

2017-01-01

The reasons for the start and end of the induction period of cement hydration remain topic of controversy. One long-standing hypothesis is that a thin metastable hydrate forming on the surface of cement grains significantly reduces the particle dissolution rate; the eventual disappearance of this layer re-establishes higher dissolution rates at the beginning of the acceleration period. However, the importance, or even the existence, of this metastable layer has been questioned because it cannot be directly detected in most experiments. In this work, a combined analysis using nano-tomography and nano-X-ray fluorescence makes the direct imaging of early hydration products possible. These novel X-ray imaging techniques provide quantitative measurements of 3D structure, chemical composition, and mass density of the hydration products during the induction period. This work does not observe a low density product on the surface of the particle, but does provide insights into the formation of etch pits and the subsequent hydration products that fill them. PMID:28919638

Partitioning direct and indirect effects reveals the response of water-limited ecosystems to elevated CO2.

PubMed

Fatichi, Simone; Leuzinger, Sebastian; Paschalis, Athanasios; Langley, J Adam; Donnellan Barraclough, Alicia; Hovenden, Mark J

2016-10-24

Increasing concentrations of atmospheric carbon dioxide are expected to affect carbon assimilation and evapotranspiration (ET), ultimately driving changes in plant growth, hydrology, and the global carbon balance. Direct leaf biochemical effects have been widely investigated, whereas indirect effects, although documented, elude explicit quantification in experiments. Here, we used a mechanistic model to investigate the relative contributions of direct (through carbon assimilation) and indirect (via soil moisture savings due to stomatal closure, and changes in leaf area index) effects of elevated CO 2 across a variety of ecosystems. We specifically determined which ecosystems and climatic conditions maximize the indirect effects of elevated CO 2 The simulations suggest that the indirect effects of elevated CO 2 on net primary productivity are large and variable, ranging from less than 10% to more than 100% of the size of direct effects. For ET, indirect effects were, on average, 65% of the size of direct effects. Indirect effects tended to be considerably larger in water-limited ecosystems. As a consequence, the total CO 2 effect had a significant, inverse relationship with the wetness index and was directly related to vapor pressure deficit. These results have major implications for our understanding of the CO 2 response of ecosystems and for global projections of CO 2 fertilization, because, although direct effects are typically understood and easily reproducible in models, simulations of indirect effects are far more challenging and difficult to constrain. Our findings also provide an explanation for the discrepancies between experiments in the total CO 2 effect on net primary productivity.

Aperture-based antihydrogen gravity experiment: Parallel plate geometry

NASA Astrophysics Data System (ADS)

Rocha, J. R.; Hedlof, R. M.; Ordonez, C. A.

2013-10-01

An analytical model and a Monte Carlo simulation are presented of an experiment that could be used to determine the direction of the acceleration of antihydrogen due to gravity. The experiment would rely on methods developed by existing antihydrogen research collaborations. The configuration consists of two circular, parallel plates that have an axis of symmetry directed away from the center of the earth. The plates are separated by a small vertical distance, and include one or more pairs of circular barriers that protrude from the upper and lower plates, thereby forming an aperture between the plates. Antihydrogen annihilations that occur just beyond each barrier, within a "shadow" region, are asymmetric on the upper plate relative to the lower plate. The probability for such annihilations is determined for a point, line and spheroidal source of antihydrogen. The production of 100,000 antiatoms is predicted to be necessary for the aperture-based experiment to indicate the direction of free fall acceleration of antimatter, provided that antihydrogen is produced within a sufficiently small antiproton plasma at a temperature of 4 K.

Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass.

PubMed

Spinelli, Jessica B; Yoon, Haejin; Ringel, Alison E; Jeanfavre, Sarah; Clish, Clary B; Haigis, Marcia C

2017-11-17

Ammonia is a ubiquitous by-product of cellular metabolism; however, the biological consequences of ammonia production are not fully understood, especially in cancer. We found that ammonia is not merely a toxic waste product but is recycled into central amino acid metabolism to maximize nitrogen utilization. In our experiments, human breast cancer cells primarily assimilated ammonia through reductive amination catalyzed by glutamate dehydrogenase (GDH); secondary reactions enabled other amino acids, such as proline and aspartate, to directly acquire this nitrogen. Metabolic recycling of ammonia accelerated proliferation of breast cancer. In mice, ammonia accumulated in the tumor microenvironment and was used directly to generate amino acids through GDH activity. These data show that ammonia is not only a secreted waste product but also a fundamental nitrogen source that can support tumor biomass. Copyright © 2017, American Association for the Advancement of Science.

The dynamic effect of reading direction habit on spatial asymmetry of image perception.

PubMed

Afsari, Zaeinab; Ossandón, José P; König, Peter

2016-09-01

Exploration of images after stimulus onset is initially biased to the left. Here, we studied the causes of such an asymmetry and investigated effects of reading habits, text primes, and priming by systematically biased eye movements on this spatial bias in visual exploration. Bilinguals first read text primes with right-to-left (RTL) or left-to-right (LTR) reading directions and subsequently explored natural images. In Experiment 1, native RTL speakers showed a leftward free-viewing shift after reading LTR primes but a weaker rightward bias after reading RTL primes. This demonstrates that reading direction dynamically influences the spatial bias. However, native LTR speakers who learned an RTL language late in life showed a leftward bias after reading either LTR or RTL primes, which suggests the role of habit formation in the production of the spatial bias. In Experiment 2, LTR bilinguals showed a slightly enhanced leftward bias after reading LTR text primes in their second language. This might contribute to the differences of native RTL and LTR speakers observed in Experiment 1. In Experiment 3, LTR bilinguals read normal (LTR, habitual reading) and mirrored left-to-right (mLTR, nonhabitual reading) texts. We observed a strong leftward bias in both cases, indicating that the bias direction is influenced by habitual reading direction and is not secondary to the actual reading direction. This is confirmed in Experiment 4, in which LTR participants were asked to follow RTL and LTR moving dots in prior image presentation and showed no change in the normal spatial bias. In conclusion, the horizontal bias is a dynamic property and is modulated by habitual reading direction.

The direct aromatization of methane

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marcelin, G.; Oukaci, R.; Migone, R.A.

1995-12-31

The thermal decomposition of methane shows significant potential as a process for the production of higher unsaturated and aromatic hydrocarbons when the extent of the reaction is limited. Thermodynamic calculations have shown that when the reaction is limited to the formation of C{sub 2} to C{sub 10} products, yields of aromatics can exceed 40% at temperatures of 1200{degrees}C. Preliminary experiments have shown that when the reaction is limited to the formation of C{sub 2} to C{sub 10} products, yields of aromatics can exceed 40% at temperatures of 1200{degrees}C. Preliminary experiments have shown that cooling the product and reacting gases asmore » the reaction proceeds can significantly reduce or eliminate the formation of solid carbon and heavier (C{sub 10+}) materials. Much work remains to be done in optimizing the quenching process and this is one of the goals of this program. Means to lower the temperature of the reaction are being studied as this result in a more feasible commercial process due to savings realized in energy and material of construction costs. The use of free-radical generators and catalysts will be investigated as a means of lowering the reaction temperature thus allowing faster quenching. It is highly likely that such studies will lead to a successful direct methane to higher hydrocarbon process.« less

Accelerator experiments on the contribution of secondary particles to the production of cosmogenic nuclides in meteorites

NASA Technical Reports Server (NTRS)

Dragovitsch, P.; Englert, P.

1985-01-01

Through the interaction of galactic cosmic particle radiation (GCR) a wide variety of cosmogenic nuclides is produced in meteorites. They provide historical information about the cosmic radiation and the bombarded meteorites. An important way to understand the production mechanisms of cosmogenic nuclides in meteorites is to gather information about the depth and size dependence of the build-up of Galactic Rays Cosmic-secondary particles within meteorites of different sizes and chemical compositions. Simulation experiments with meteorite models offer an alternative to direct observation providing a data basis to describe the development and action of the secondary cascade induced by the GCR in meteorites.

Muon Production Height investigated by the Air-Shower Experiment KASCADE-Grande

NASA Astrophysics Data System (ADS)

Doll, P.; Apel, W. D.; Arteaga, J. C.; Badea, F.; Bekk, K.; Bertaina, M.; Blümer, H.; Bozdog, H.; Brancus, I. M.; Brüggemann, M.; Buchholz, P.; Cantoni, E.; Chiavassa, A.; Cossavella, F.; Daumiller, K.; de Souza, V.; di Pierro, F.; Engel, R.; Engler, J.; Finger, M.; Fuhrmann, D.; Ghia, P. L.; Gils, H. J.; Glasstetter, R.; Grupen, C.; Haungs, A.; Heck, D.; Hörandel, J. R.; Huege, T.; Isar, P. G.; Kampert, K.-H.; Kang, D.; Kickelbick, D.; Klages, H. O.; Kolotaev, Y.; Łuczak, P.; Mathes, H. J.; Mayer, H. J.; Milke, J.; Mitrica, B.; Morello, C.; Navarra, G.; Nehls, S.; Oehlschläger, J.; Ostapchenko, S.; Over, S.; Petcu, M.; Pierog, T.; Rebel, H.; Roth, M.; Schieler, H.; Schröder, F.; Sima, O.; Stümpert, M.; Toma, G.; Trinchero, G. C.; Ulrich, H.; van Buren, J.; Walkowiak, W.; Weindl, A.; Wochele, J.; Wommer, M.; Zabierowski, J.; KASCADE-Grande Collaboration

2009-12-01

A large area (128 m2) Muon Tracking Detector (MTD), located within the KASCADE experiment, has been built with the aim to identify muons ( E>0.8 GeV) and their directions in extensive air showers by track measurements under more than 18 r.l. shielding. The orientation of the muon track with respect to the shower axis is expressed in terms of the radial- and tangential angles. By means of triangulation the muon production height H is determined. By means of H, a transition from light to heavy cosmic ray primary particles with increasing shower energy E from 1-10 PeV is observed.

Productivity, Slack, and Time Theft in the Soviet Economy: Evidence from the Soviet Interview Project

DTIC Science & Technology

1985-09-01

enterprise, changes in personal living standards, tightness of enterprise targets, and so on. The natural question is how these perceptions affect...microeconomic working arrangements, and respondent-specific questions concerning their own personal experiences and impressions. These two types of responses...directly to speak about personal workplace experiences, so there is less dznger of second-hand generalizatIons. The slack questions address

Field experience silvicultural cleaning project in young spruce and fir stands in central Nova Scotia

Treesearch

Theodore C. Tryon; Thomas W. Hartranft

1977-01-01

Silvicultural cleaning production varied from .15 to .34 acres per man day using light weight chain saws in young Spruce and Fir stands in Central Nova Scotia. Direct labor and saw costs, in cleaning young softwood stands in Nova Scotia, can be expected to range generally from $55.00 to $90.00 per acre, depending on crew experience, stand density, and equipment used....

Forest research notes, Pacific Northwest Forest Experiment Station, No. 04, June 27, 1930.

Treesearch

1930-01-01

Some definite figures on the survival and seed production of seed trees left on national forest timber sales in the Douglas fir region are now available for six representative areas where approximately two trees were left per acre. The studies mere made by men in charge of timber sales on the national forests under the direction of the Experiment Station, and have now...

The role of similarity, sound and awareness in the appreciation of visual artwork via motor simulation.

PubMed

McLean, Christine; Want, Stephen C; Dyson, Benjamin J

2015-04-01

One way to increase art appreciation is to create congruency between the actions performed by the artist and the actions performed by the viewer. Leder, Bar, and Topolinski (2012) successfully created such a link by asking participants to make either stroking or stippling motions while viewing stroke-style and pointillist-style paintings. We carried out a direct replication of Leder et al. (2012) in Experiment 1 but failed to reproduce their results. In Experiment 2, we achieved the desired cross-over interaction between image and action but only when the relationship was made more transparent. Experiment 3 demonstrated that this effect requires a motor component and cannot be reproduced by simply hearing the sounds associated with drawing production. Experiment 4 investigated whether either an external manipulation or a self-report measure of awareness of the image-action match modulated the liking ratings, in addition to artwork familiarity and participants' own hypotheses regarding the direction of the image-action effect. Participants who predicted that congruent relationships between what they saw and what they did would increase liking showed enhanced congruency effects. The links between historical production and contemporary exposure to art may then be an overt rather than covert process. Copyright © 2015 Elsevier B.V. All rights reserved.

AN EXPERIMENTAL STUDY OF THE DIRECT PRODUCTION OF PI MESONS BY HIGH-ENERGY ELECTRONS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hand, L.N.

1962-04-01

The direct production of pi mesons by high-energy electrons was studied experimentally as an indirect measurement of the charge and magnetic structure of the neutron. The reactions of interest are: e/sup -/ + p/sup +/ yields e/sup -/ + p/sup ~+/ + i/sup 0/ and e/sup -/ + p/sup +/ yields e/sup -/ + n/sup 0/ + pi /sup +/. Only the final electro n is observed. Physically the experiment consists of passing a beam of electrons through a liquid hydrogen target. Electrons scattered at a given angle and having momenta within a certain range about a selected value aremore » analyzed with a magnetic spectrometer and counted by virtue of their Cerenkov light in a counter filled with paraffin oil. This counter has been designed to minimize the background. Counting rates for positive and negative particles are recorded for each momentum setting. The initial and final energies may be programmed to vary either the pionnucleon dynamics or the invariant four-momentum transfer (q/sup 2/) independently. The behavior of the cross section as a function of the latter variable is in part determined by charge and magnetic moment distributions of the proton and neutron and by the charge distribution of the pion. It is unfortunate that the sensitivity of the present experiment to the pion size is rather low, as no published information exists on this quantity. One important difference between electroproduction and the more usual gamma-ray excitation of mesons is the possibility of inducing the above reactions with the electric field possessed by the electron along its direction of motion. A simple proof was found of a theorem which permits a purely experimental determination of the amount of this longitudinal interaction relative to the transverse interaction occurring in both the electron and gamma-ray production of pions. This theorem is applicable to a wide class of electron scattering experiments. The results indicate the absence of any longitudinal pion production in the energy region covered by this experiment. This work represents a continuation and extension of two previous experiments done at Stanford. An unsuccessful search was made at high energies for effects of the socalled second resonance'' in the pion-nucleon interaction. Several experimental checks were raade on the validity of from deuteriura.« less

Synthesis of Meso-Octamethylporphyrinogen: An Undergraduate Laboratory Mini-Scale Experiment in Organic Heterocyclic Chemistry

ERIC Educational Resources Information Center

Sobral, Abilio J. F. N.

2005-01-01

The synthesis of meso-octamethylporphyrinogen that involves a mini-scale preparation and uses acetone as reactant and also as solvent is presented. It results in a product of almost analytical grade directly from the reaction medium.

Post-transition state dynamics and product energy partitioning following thermal excitation of the F⋯HCH2CN transition state: Disagreement with experiment

NASA Astrophysics Data System (ADS)

Pratihar, Subha; Ma, Xinyou; Xie, Jing; Scott, Rebecca; Gao, Eric; Ruscic, Branko; Aquino, Adelia J. A.; Setser, Donald W.; Hase, William L.

2017-10-01

Born-Oppenheimer direct dynamics simulations were performed to study atomistic details of the F + CH3CN → HF + CH2CN H-atom abstraction reaction. The simulation trajectories were calculated with a combined M06-2X/MP2 algorithm utilizing the 6-311++G** basis set. The experiments were performed at 300 K, and assuming the accuracy of transition state theory (TST), the trajectories were initiated at the F⋯HCH2CN abstraction TS with a 300 K Boltzmann distribution of energy and directed towards products. Recrossing of the TS was negligible, confirming the accuracy of TST. HF formation was rapid, occurring within 0.014 ps of the trajectory initiation. The intrinsic reaction coordinate (IRC) for reaction involves rotation of HF about CH2CN and then trapping in the CH2CN⋯HF post-reaction potential energy well of ˜10 kcal/mol with respect to the HF + CH2CN products. In contrast to this IRC, five different trajectory types were observed: the majority proceeded by direct H-atom transfer and only 11% approximately following the IRC. The HF vibrational and rotational quantum numbers, n and J, were calculated when HF was initially formed and they increase as potential energy is released in forming the HF + CH2CN products. The population of the HF product vibrational states is only in qualitative agreement with experiment, with the simulations showing depressed and enhanced populations of the n = 1 and 2 states as compared to experiment. Simulations with an anharmonic zero-point energy constraint gave product distributions for relative translation, HF rotation, HF vibration, CH2CN rotation, and CH2CN vibration as 5%, 11%, 60%, 7%, and 16%, respectively. In contrast, the experimental energy partitioning percentages to HF rotation and vibration are 6% and 41%. Comparisons are made between the current simulation and those for other F + H-atom abstraction reactions. The simulation product energy partitioning and HF vibrational population for F + CH3CN → HF + CH2CN resemble those for other reactions. A detailed discussion is given of possible origins of the difference between the simulation and experimental energy partitioning dynamics for F + CH3CN → HF + CH2CN. The F + CH3CN reaction also forms the CH3C(F)N intermediate, in which the F-atom adds to the C≡N bond. However, this intermediate and F⋯CH3CN and CH3CN⋯F van der Waals complexes are not expected to affect the F + CH3CN → HF + CH2CN product energy partitioning.

Post-transition state dynamics and product energy partitioning following thermal excitation of the F∙∙∙HCH 2 CN transition state: Disagreement with experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pratihar, Subha; Ma, Xinyou; Xie, Jing

Born-Oppenheimer direct dynamics simulations were performed to study atomistic details of the F + CH 3CN → HF + CH 2CN H-atom abstraction reaction. The simulation trajectories were calculated with a combined M06-2X/MP2 algorithm utilizing the 6-311++G** basis set. In accord with experiment and assuming the accuracy of transition state theory (TST), the trajectories were initiated at the F-HCH 2CN abstraction TS with a 300 K Boltzmann distribution of energy and directed towards products. Recrossing of the TS was negligible, confirming the accuracy of TST for the simulation. HF formation was rapid, occurring within 0.014 ps of the trajectory initiation.more » The intrinsic reaction coordinate (IRC) for reaction involves rotation of HF about CH 2CN and then trapping in the CH 2CN-HF post-reaction potential energy well of ~10 kcal/mol with respect to the HF + CH 2CN products. In contrast to this IRC, five different trajectory types were observed, with the majority involving direct dissociation and only 11% approximately following the IRC. The HF vibrational and rotational quantum numbers, n and J, were calculated when HF was initially formed and they increase as potential energy is released in forming the HF + CH 2CN products. The population of the HF product vibrational states is only in qualitative agreement with experiment, with the simulations showing depressed and enhanced populations of the n = 1 and 2 states as compared to experiment. From the simulations and with an anharmonic zero-point energy constraint, the percentage partitioning of the product energy to relative translation, HF rotation, HF vibration, CH 2CN rotation and CH 2CN vibration is 5, 11, 60, 7, and 16%, respectively. In contrast the experimental energy partitioning percentages to HF rotation and vibration are 6 and 41%. Comparisons are made between the current simulation and those for other F + H-atom abstraction reactions. The simulation product energy partitioning and HF vibrational population for F + CH 3CN → HF + CH 2CN are similar to those for these other reactions. A detailed discussion is given of possible origins of the difference between the simulation and experimental energy partitioning dynamics for the F + CH 3CN → HF + CH 2CN reaction. The F + CH 3CN reaction also forms the CH 3C(F)N intermediate, in which the F-atom adds to the C≡N bond. However, this intermediate and the F---CH 3CN and CH 3CN-F van der Waals complexes are not expected to affect the F + CH 3CN → HF + CH 2CN product energy partitioning.« less

Post-transition state dynamics and product energy partitioning following thermal excitation of the F⋯HCH2CN transition state: Disagreement with experiment.

PubMed

Pratihar, Subha; Ma, Xinyou; Xie, Jing; Scott, Rebecca; Gao, Eric; Ruscic, Branko; Aquino, Adelia J A; Setser, Donald W; Hase, William L

2017-10-14

Born-Oppenheimer direct dynamics simulations were performed to study atomistic details of the F + CH 3 CN → HF + CH 2 CN H-atom abstraction reaction. The simulation trajectories were calculated with a combined M06-2X/MP2 algorithm utilizing the 6-311++G** basis set. The experiments were performed at 300 K, and assuming the accuracy of transition state theory (TST), the trajectories were initiated at the F⋯HCH 2 CN abstraction TS with a 300 K Boltzmann distribution of energy and directed towards products. Recrossing of the TS was negligible, confirming the accuracy of TST. HF formation was rapid, occurring within 0.014 ps of the trajectory initiation. The intrinsic reaction coordinate (IRC) for reaction involves rotation of HF about CH 2 CN and then trapping in the CH 2 CN⋯HF post-reaction potential energy well of ∼10 kcal/mol with respect to the HF + CH 2 CN products. In contrast to this IRC, five different trajectory types were observed: the majority proceeded by direct H-atom transfer and only 11% approximately following the IRC. The HF vibrational and rotational quantum numbers, n and J, were calculated when HF was initially formed and they increase as potential energy is released in forming the HF + CH 2 CN products. The population of the HF product vibrational states is only in qualitative agreement with experiment, with the simulations showing depressed and enhanced populations of the n = 1 and 2 states as compared to experiment. Simulations with an anharmonic zero-point energy constraint gave product distributions for relative translation, HF rotation, HF vibration, CH 2 CN rotation, and CH 2 CN vibration as 5%, 11%, 60%, 7%, and 16%, respectively. In contrast, the experimental energy partitioning percentages to HF rotation and vibration are 6% and 41%. Comparisons are made between the current simulation and those for other F + H-atom abstraction reactions. The simulation product energy partitioning and HF vibrational population for F + CH 3 CN → HF + CH 2 CN resemble those for other reactions. A detailed discussion is given of possible origins of the difference between the simulation and experimental energy partitioning dynamics for F + CH 3 CN → HF + CH 2 CN. The F + CH 3 CN reaction also forms the CH 3 C(F)N intermediate, in which the F-atom adds to the C≡N bond. However, this intermediate and F⋯CH 3 CN and CH 3 CN⋯F van der Waals complexes are not expected to affect the F + CH 3 CN → HF + CH 2 CN product energy partitioning.

Direct thermal water splitting by concentrated solar radiation for hydrogen production. Phase O: Proof of concept experiment

NASA Technical Reports Server (NTRS)

Genequand, P.

1980-01-01

The direct production of hydrogen from water and solar energy concentrated into a high temperature aperture is described. A solar powered reactor able to dissociate water vapor and to separate the reaction product at high temperature was developed, and direct water splitting has been achieved in a laboratory reactor. Water vapor and radiative heating from a carbon dioxide laser are fed into the reactor, and water vapor enriched in hydrogen and water vapor enriched in oxygen are produced. The enriched water vapors are separated through a separation membrane, a small disc of zirconium dioxide heated to a range of 1800 k to 2800 k. To avoid water vapor condensation within the reactor, the total pressure within the reactor was limited to 0.15 torr. A few modifications would enable the reactor to be operated at an increased pressure of a few torrs. More substantial modifications would allow for a reaction pressure of 0.1 atmosphere.

Maximizing efficiency of rumen microbial protein production

PubMed Central

Hackmann, Timothy J.; Firkins, Jeffrey L.

2015-01-01

Rumen microbes produce cellular protein inefficiently partly because they do not direct all ATP toward growth. They direct some ATP toward maintenance functions, as long-recognized, but they also direct ATP toward reserve carbohydrate synthesis and energy spilling (futile cycles that dissipate heat). Rumen microbes expend ATP by vacillating between (1) accumulation of reserve carbohydrate after feeding (during carbohydrate excess) and (2) mobilization of that carbohydrate thereafter (during carbohydrate limitation). Protozoa account for most accumulation of reserve carbohydrate, and in competition experiments, protozoa accumulated nearly 35-fold more reserve carbohydrate than bacteria. Some pure cultures of bacteria spill energy, but only recently have mixed rumen communities been recognized as capable of the same. When these communities were dosed glucose in vitro, energy spilling could account for nearly 40% of heat production. We suspect that cycling of glycogen (a major reserve carbohydrate) is a major mechanism of spilling; such cycling has already been observed in single-species cultures of protozoa and bacteria. Interconversions of short-chain fatty acids (SCFA) may also expend ATP and depress efficiency of microbial protein production. These interconversions may involve extensive cycling of intermediates, such as cycling of acetate during butyrate production in certain butyrivibrios. We speculate this cycling may expend ATP directly or indirectly. By further quantifying the impact of reserve carbohydrate accumulation, energy spilling, and SCFA interconversions on growth efficiency, we can improve prediction of microbial protein production and guide efforts to improve efficiency of microbial protein production in the rumen. PMID:26029197

Data Acquisition and Mass Storage

NASA Astrophysics Data System (ADS)

Vande Vyvre, P.

2004-08-01

The experiments performed at supercolliders will constitute a new challenge in several disciplines of High Energy Physics and Information Technology. This will definitely be the case for data acquisition and mass storage. The microelectronics, communication, and computing industries are maintaining an exponential increase of the performance of their products. The market of commodity products remains the largest and the most competitive market of technology products. This constitutes a strong incentive to use these commodity products extensively as components to build the data acquisition and computing infrastructures of the future generation of experiments. The present generation of experiments in Europe and in the US already constitutes an important step in this direction. The experience acquired in the design and the construction of the present experiments has to be complemented by a large R&D effort executed with good awareness of industry developments. The future experiments will also be expected to follow major trends of our present world: deliver physics results faster and become more and more visible and accessible. The present evolution of the technologies and the burgeoning of GRID projects indicate that these trends will be made possible. This paper includes a brief overview of the technologies currently used for the different tasks of the experimental data chain: data acquisition, selection, storage, processing, and analysis. The major trends of the computing and networking technologies are then indicated with particular attention paid to their influence on the future experiments. Finally, the vision of future data acquisition and processing systems and their promise for future supercolliders is presented.

Evaluation of pulsed streamer corona experiments to determine the O* radical yield

NASA Astrophysics Data System (ADS)

van Heesch, E. J. M.; Winands, G. J. J.; Pemen, A. J. M.

2008-12-01

The production of O* radicals in air by a pulsed streamer plasma is studied by integration of a large set of precise experimental data and the chemical kinetics of ozone production. The measured data comprise ozone production, plasma energy, streamer volume, streamer length, streamer velocity, humidity and gas-flow rate. Instead of entering input parameters into a kinetic model to calculate the end products the opposite strategy is followed. Since the amount of end-products (ozone) is known from the measurements the model had to be applied in the reverse direction to determine the input parameters, i.e. the O* radical concentration.

NuMI Flux Predictions for NOvA and MINERvA

NASA Astrophysics Data System (ADS)

Aliaga Soplin, Leonidas; Nova Collaboration; Minerva Collaboration

2017-01-01

The determination of the neutrino flux in any conventional neutrino beam presents a challenge for the current and future short and long baseline neutrino experiments. The uncertainties associated with the production and attenuation of the hadrons in the beamline materials along with those associated with the beam optics have a big effect in the knowledge of the flux. For experiments like MINERvA and NOvA, understanding the flux is crucial since it enters directly into every neutrino-nucleus cross-section measurement. The majority of this work involves predicting the neutrino flux using dedicated hadron production measurements from hadron-nucleus collisions. The predictions at the MINERvA and NOvA near detectors are presented as well as the results of incorporating in-situ MINERvA data that can provide additional constraints. These results have been fully implemented in MINERvA and they are currently use for its cross-section analysis. The implementation for NoVA is underway. The procedure and conclusions of this work will have a big impact on future hadron production experiments and on determining the flux for the upcoming DUNE experiment.

Spin and Wind Directions II: A Bell State Quantum Model.

PubMed

Aerts, Diederik; Arguëlles, Jonito Aerts; Beltran, Lester; Geriente, Suzette; Sassoli de Bianchi, Massimiliano; Sozzo, Sandro; Veloz, Tomas

2018-01-01

In the first half of this two-part article (Aerts et al. in Found Sci. doi:10.1007/s10699-017-9528-9, 2017b), we analyzed a cognitive psychology experiment where participants were asked to select pairs of directions that they considered to be the best example of Two Different Wind Directions , and showed that the data violate the CHSH version of Bell's inequality, with same magnitude as in typical Bell-test experiments in physics. In this second part, we complete our analysis by presenting a symmetrized version of the experiment, still violating the CHSH inequality but now also obeying the marginal law, for which we provide a full quantum modeling in Hilbert space, using a singlet state and suitably chosen product measurements. We also address some of the criticisms that have been recently directed at experiments of this kind, according to which they would not highlight the presence of genuine forms of entanglement. We explain that these criticisms are based on a view of entanglement that is too restrictive, thus unable to capture all possible ways physical and conceptual entities can connect and form systems behaving as a whole. We also provide an example of a mechanical model showing that the violations of the marginal law and Bell inequalities are generally to be associated with different mechanisms.

Managing resources and reducing waste in healthcare settings.

PubMed

Minogue, Virginia; Wells, Bill

2016-05-18

The NHS is under pressure to increase its effectiveness and productivity. Nurses are tasked with delivering effective and efficient care, as well as improving patient safety, experiences and results. The reduction of waste in service delivery, care and treatment can release time and resources for nurses to engage in direct patient care. Nurses have an important role in reducing waste and influencing other professionals in the healthcare environment to increase their efficiency and productivity.

Search for sneutrino production in eμ final states in 5.3 fb-1 of pp collisions at square root s =1.96 TeV.

PubMed

Abazov, V M; Abbott, B; Abolins, M; Acharya, B S; Adams, M; Adams, T; Alexeev, G D; Alkhazov, G; Alton, A; Alverson, G; Alves, G A; Ancu, L S; Aoki, M; Arnoud, Y; Arov, M; Askew, A; Asman, B; Atramentov, O; Avila, C; BackusMayes, J; Badaud, F; Bagby, L; Baldin, B; Bandurin, D V; Banerjee, S; Barberis, E; Baringer, P; Barreto, J; Bartlett, J F; Bassler, U; Beale, S; Bean, A; Begalli, M; Begel, M; Belanger-Champagne, C; Bellantoni, L; Benitez, J A; Beri, S B; Bernardi, G; Bernhard, R; Bertram, I; Besançon, M; Beuselinck, R; Bezzubov, V A; Bhat, P C; Bhatnagar, V; Blazey, G; Blessing, S; Bloom, K; Boehnlein, A; Boline, D; Bolton, T A; Boos, E E; Borissov, G; Bose, T; Brandt, A; Brandt, O; Brock, R; Brooijmans, G; Bross, A; Brown, D; Brown, J; Bu, X B; Buchholz, D; Buehler, M; Buescher, V; Bunichev, V; Burdin, S; Burnett, T H; Buszello, C P; Calpas, B; Calvet, S; Camacho-Pérez, E; Carrasco-Lizarraga, M A; Carrera, E; Casey, B C K; Castilla-Valdez, H; Chakrabarti, S; Chakraborty, D; Chan, K M; Chandra, A; Chen, G; Chevalier-Théry, S; Cho, D K; Cho, S W; Choi, S; Choudhary, B; Christoudias, T; Cihangir, S; Claes, D; Clutter, J; Cooke, M; Cooper, W E; Corcoran, M; Couderc, F; Cousinou, M-C; Croc, A; Cutts, D; Cwiok, M; Das, A; Davies, G; De, K; de Jong, S J; De La Cruz-Burelo, E; Déliot, F; Demarteau, M; Demina, R; Denisov, D; Denisov, S P; Desai, S; DeVaughan, K; Diehl, H T; Diesburg, M; Ding, P F; Dominguez, A; Dorland, T; Dubey, A; Dudko, L V; Duggan, D; Duperrin, A; Dutt, S; Dyshkant, A; Eads, M; Edmunds, D; Ellison, J; Elvira, V D; Enari, Y; Eno, S; Evans, H; Evdokimov, A; Evdokimov, V N; Facini, G; Ferapontov, A V; Ferbel, T; Fiedler, F; Filthaut, F; Fisher, W; Fisk, H E; Fortner, M; Fox, H; Fuess, S; Gadfort, T; Garcia-Bellido, A; Gavrilov, V; Gay, P; Geist, W; Geng, W; Gerbaudo, D; Gerber, C E; Gershtein, Y; Ginther, G; Golovanov, G; Goussiou, A; Grannis, P D; Greder, S; Greenlee, H; Greenwood, Z D; Gregores, E M; Grenier, G; Gris, Ph; Grivaz, J-F; Grohsjean, A; Grünendahl, S; Grünewald, M W; Guo, F; Guo, J; Gutierrez, G; Gutierrez, P; Haas, A; Hagopian, S; Haley, J; Han, L; Harder, K; Harel, A; Hauptman, J M; Hays, J; Hebbeker, T; Hedin, D; Hegab, H; Heinson, A P; Heintz, U; Hensel, C; Heredia-De La Cruz, I; Herner, K; Hesketh, G; Hildreth, M D; Hirosky, R; Hoang, T; Hobbs, J D; Hoeneisen, B; Hohlfeld, M; Hossain, S; Hubacek, Z; Huske, N; Hynek, V; Iashvili, I; Illingworth, R; Ito, A S; Jabeen, S; Jaffré, M; Jain, S; Jamin, D; Jesik, R; Johns, K; Johnson, M; Johnston, D; Jonckheere, A; Jonsson, P; Joshi, J; Juste, A; Kaadze, K; Kajfasz, E; Karmanov, D; Kasper, P A; Katsanos, I; Kehoe, R; Kermiche, S; Khalatyan, N; Khanov, A; Kharchilava, A; Kharzheev, Y N; Khatidze, D; Kirby, M H; Kohli, J M; Kozelov, A V; Kraus, J; Kumar, A; Kupco, A; Kurča, T; Kuzmin, V A; Kvita, J; Lammers, S; Landsberg, G; Lebrun, P; Lee, H S; Lee, S W; Lee, W M; Lellouch, J; Li, L; Li, Q Z; Lietti, S M; Lim, J K; Lincoln, D; Linnemann, J; Lipaev, V V; Lipton, R; Liu, Y; Liu, Z; Lobodenko, A; Lokajicek, M; Love, P; Lubatti, H J; Luna-Garcia, R; Lyon, A L; Maciel, A K A; Mackin, D; Madar, R; Magaña-Villalba, R; Malik, S; Malyshev, V L; Maravin, Y; Martínez-Ortega, J; McCarthy, R; McGivern, C L; Meijer, M M; Melnitchouk, A; Menezes, D; Mercadante, P G; Merkin, M; Meyer, A; Meyer, J; Mondal, N K; Muanza, G S; Mulhearn, M; Nagy, E; Naimuddin, M; Narain, M; Nayyar, R; Neal, H A; Negret, J P; Neustroev, P; Nilsen, H; Novaes, S F; Nunnemann, T; Obrant, G; Onoprienko, D; Orduna, J; Osman, N; Osta, J; Otero y Garzón, G J; Owen, M; Padilla, M; Pangilinan, M; Parashar, N; Parihar, V; Park, S K; Parsons, J; Partridge, R; Parua, N; Patwa, A; Penning, B; Perfilov, M; Peters, K; Peters, Y; Petrillo, G; Pétroff, P; Piegaia, R; Piper, J; Pleier, M-A; Podesta-Lerma, P L M; Podstavkov, V M; Pol, M-E; Polozov, P; Popov, A V; Prewitt, M; Price, D; Protopopescu, S; Qian, J; Quadt, A; Quinn, B; Rangel, M S; Ranjan, K; Ratoff, P N; Razumov, I; Renkel, P; Rich, P; Rijssenbeek, M; Ripp-Baudot, I; Rizatdinova, F; Rominsky, M; Royon, C; Rubinov, P; Ruchti, R; Safronov, G; Sajot, G; Sánchez-Hernández, A; Sanders, M P; Sanghi, B; Santos, A S; Savage, G; Sawyer, L; Scanlon, T; Schamberger, R D; Scheglov, Y; Schellman, H; Schliephake, T; Schlobohm, S; Schwanenberger, C; Schwienhorst, R; Sekaric, J; Severini, H; Shabalina, E; Shary, V; Shchukin, A A; Shivpuri, R K; Simak, V; Sirotenko, V; Skubic, P; Slattery, P; Smirnov, D; Smith, K J; Snow, G R; Snow, J; Snyder, S; Söldner-Rembold, S; Sonnenschein, L; Sopczak, A; Sosebee, M; Soustruznik, K; Spurlock, B; Stark, J; Stolin, V; Stoyanova, D A; Strauss, E; Strauss, M; Strom, D; Stutte, L; Svoisky, P; Takahashi, M; Tanasijczuk, A; Taylor, W; Titov, M; Tokmenin, V V; Tsybychev, D; Tuchming, B; Tully, C; Tuts, P M; Uvarov, L; Uvarov, S; Uzunyan, S; Van Kooten, R; van Leeuwen, W M; Varelas, N; Varnes, E W; Vasilyev, I A; Verdier, P; Vertogradov, L S; Verzocchi, M; Vesterinen, M; Vilanova, D; Vint, P; Vokac, P; Wahl, H D; Wang, M H L S; Warchol, J; Watts, G; Wayne, M; Weber, M; Wetstein, M; White, A; Wicke, D; Williams, M R J; Wilson, G W; Wimpenny, S J; Wobisch, M; Wood, D R; Wyatt, T R; Xie, Y; Xu, C; Yacoob, S; Yamada, R; Yang, W-C; Yasuda, T; Yatsunenko, Y A; Ye, Z; Yin, H; Yip, K; Yoo, H D; Youn, S W; Yu, J; Zelitch, S; Zhao, T; Zhou, B; Zhu, J; Zielinski, M; Zieminska, D; Zivkovic, L

2010-11-05

We report the results of a search for R parity violating (RPV) interactions leading to the production of supersymmetric sneutrinos decaying into eμ final states using 5.3 fb-1 of integrated luminosity collected by the D0 experiment at the Fermilab Tevatron Collider. Having observed no evidence for production of eμ resonances, we set direct bounds on the RPV couplings λ311' and λ312 as a function of sneutrino mass.

The (mis)use of subjective process measures in software engineering

NASA Technical Reports Server (NTRS)

Valett, Jon D.; Condon, Steven E.

1993-01-01

A variety of measures are used in software engineering research to develop an understanding of the software process and product. These measures fall into three broad categories: quantitative, characteristics, and subjective. Quantitative measures are those to which a numerical value can be assigned, for example effort or lines of code (LOC). Characteristics describe the software process or product; they might include programming language or the type of application. While such factors do not provide a quantitative measurement of a process or product, they do help characterize them. Subjective measures (as defined in this study) are those that are based on the opinion or opinions of individuals; they are somewhat unique and difficult to quantify. Capturing of subjective measure data typically involves development of some type of scale. For example, 'team experience' is one of the subjective measures that were collected and studied by the Software Engineering Laboratory (SEL). Certainly, team experience could have an impact on the software process or product; actually measuring a team's experience, however, is not a strictly mathematical exercise. Simply adding up each team member's years of experience appears inadequate. In fact, most researchers would agree that 'years' do not directly translate into 'experience.' Team experience must be defined subjectively and then a scale must be developed e.g., high experience versus low experience; or high, medium, low experience; or a different or more granular scale. Using this type of scale, a particular team's overall experience can be compared with that of other teams in the development environment. Defining, collecting, and scaling subjective measures is difficult. First, precise definitions of the measures must be established. Next, choices must be made about whose opinions will be solicited to constitute the data. Finally, care must be given to defining the right scale and level of granularity for measurement.

The Bi-Directional Prediction of Carbon Fiber Production Using a Combination of Improved Particle Swarm Optimization and Support Vector Machine.

PubMed

Xiao, Chuncai; Hao, Kuangrong; Ding, Yongsheng

2014-12-30

This paper creates a bi-directional prediction model to predict the performance of carbon fiber and the productive parameters based on a support vector machine (SVM) and improved particle swarm optimization (IPSO) algorithm (SVM-IPSO). In the SVM, it is crucial to select the parameters that have an important impact on the performance of prediction. The IPSO is proposed to optimize them, and then the SVM-IPSO model is applied to the bi-directional prediction of carbon fiber production. The predictive accuracy of SVM is mainly dependent on its parameters, and IPSO is thus exploited to seek the optimal parameters for SVM in order to improve its prediction capability. Inspired by a cell communication mechanism, we propose IPSO by incorporating information of the global best solution into the search strategy to improve exploitation, and we employ IPSO to establish the bi-directional prediction model: in the direction of the forward prediction, we consider productive parameters as input and property indexes as output; in the direction of the backward prediction, we consider property indexes as input and productive parameters as output, and in this case, the model becomes a scheme design for novel style carbon fibers. The results from a set of the experimental data show that the proposed model can outperform the radial basis function neural network (RNN), the basic particle swarm optimization (PSO) method and the hybrid approach of genetic algorithm and improved particle swarm optimization (GA-IPSO) method in most of the experiments. In other words, simulation results demonstrate the effectiveness and advantages of the SVM-IPSO model in dealing with the problem of forecasting.

Results from the HARP Experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borghi, Silvia

2006-07-11

The HARP experiment at CERN performed extensive measurements of hadronic cross-sections and secondary particle yields in the momentum range 1.5-15 GeV/c aiming at full angular coverage and full particle identification. We report about the double-differential production cross-section for positive pions, for incident protons of 12.9 GeV/c momentum hitting an aluminum target of 5% nuclear interaction length. The measurement of this cross-section has direct application to the prediction of the neutrino flux of K2K experiment and in particular on the far-near neutrino flux ratio.

Characterization of CMPO and its radiolysis products by Direct Infusion ESI-MS

DOE Office of Scientific and Technical Information (OSTI.GOV)

G. S. Groenewold; G. Elias; B. J. Mincher

2012-09-01

Direct infusion electrospray ionization-mass spectrometry (ESI-MS) approaches were developed for rapid identification of octyl,phenyl,(N,N-(diisobutyl)carbamoylmethyl) phosphine oxide (CMPO) and impurity compounds formed during alpha and gamma irradiation experiments. CMPO is an aggressive Lewis base, and produces extremely abundant metal complex ions in the ESI-MS analysis that make identification of low abundance compounds that are less nucleophilic challenging. Radiolysis products were identified using several approaches including restricting ion trapping so as to exclude the abundant natiated CMPO ions, extraction of acidic products using aqueous NaOH, and extraction of basic products using HNO3. These approaches generated protonated, natiated and deprotonated species derived frommore » CMPO degradation products formed via radiolytic cleavages of several different bonds. Cleavages of the amide and methylene-phosphoryl bonds appear to be favored by both forms of irradiation, while alpha irradiation also appears to induce cleavage of the methylene-carbonyl bond. The degradation products observed are formed from recombination of the initially formed radicals with hydrogen, methyl, isopropyl and hydroxyl radicals that are derived either from CMPO, or the dodecane solvent.« less

Production and comprehension show divergent constituent order preferences: Evidence from elicited pantomime

PubMed Central

Hall, Matthew L.; Ahn, Y. Danbi; Mayberry, Rachel I.; Ferreira, Victor S.

2015-01-01

All natural languages develop devices to communicate who did what to whom. Elicited pantomime provides one model for studying this process, by providing a window into how humans (hearing non-signers) behave in a natural communicative modality (silent gesture) without established conventions from a grammar. Most studies in this paradigm focus on production, although they sometimes make assumptions about how comprehenders would likely behave. Here, we directly assess how naïve speakers of English (Experiments 1 & 2), Korean (Experiment 1), and Turkish (Experiment 2) comprehend pantomimed descriptions of transitive events, which are either semantically reversible (Experiments 1 & 2) or not (Experiment 2). Contrary to previous assumptions, we find no evidence that Person-Person-Action sequences are ambiguous to comprehenders, who simply adopt an agent-first parsing heuristic for all constituent orders. We do find that Person-Action-Person sequences yield the most consistent interpretations, even in native speakers of SOV languages. The full range of behavior in both production and comprehension provides counter-evidence to the notion that producers’ utterances are motivated by the needs of comprehenders. Instead, we argue that production and comprehension are subject to different sets of cognitive pressures, and that the dynamic interaction between these competing pressures can help explain synchronic and diachronic constituent order phenomena in natural human languages, both signed and spoken. PMID:25642018

Direct Dynamics Simulation of the Thermal 3CH2 + 3O2 Reaction. Rate Constant and Product Branching Ratios.

PubMed

Lakshmanan, Sandhiya; Pratihar, Subha; Machado, Francisco B C; Hase, William L

2018-05-31

The reaction of 3 CH 2 with 3 O 2 is of fundamental importance in combustion, and the reaction is complex as a result of multiple extremely exothermic product channels. In the present study, direct dynamics simulations were performed to study the reaction on both the singlet and triplet potential energy surfaces (PESs). The simulations were performed at the UM06/6-311++G(d,p) level of theory. Trajectories were calculated at a temperature of 300 K, and all reactive trajectories proceeded through the carbonyl oxide Criegee intermediate, CH 2 OO, on both the singlet and triplet PESs. The triplet surface leads to only one product channel, H 2 CO + O( 3 P), while the singlet surface leads to eight product channels with their relative importance as CO + H 2 O > CO + OH + H ∼ H 2 CO + O( 1 D) > HCO + OH ∼ CO 2 + H 2 ∼ CO + H 2 + O( 1 D) > CO 2 + H + H > HCO + O( 1 D) + H. The reaction on the singlet PES is barrierless, consistent with experiment, and the total rate constant on the singlet surface is (0.93 ± 0.22) × 10 -12 cm 3 molecule -1 s -1 in comparison to the recommended experimental rate constant of 3.3 × 10 -12 cm 3 molecule -1 s -1 . The simulation product yields for the singlet PES are compared with experiment, and the most significant differences are for H, CO 2 , and H 2 O. The reaction on the triplet surface is also barrierless, inconsistent with experiment. A discussion is given of the need for future calculations to address (1) the barrier on the triplet PES for 3 CH 2 + 3 O 2 → 3 CH 2 OO, (2) the temperature dependence of the 3 CH 2 + 3 O 2 reaction rate constant and product branching ratios, and (3) the possible non-RRKM dynamics of the 1 CH 2 OO Criegee intermediate.

Monitoring volatilization products using Residual Gas Analyzers during MeV ion beam irradiations

NASA Astrophysics Data System (ADS)

Wetteland, C. J.; Kriewaldt, K.; Taylor, L. A.; McSween, H. Y.; Sickafus, K. E.

2018-03-01

The use of Residual Gas Analyzers (RGAs) during irradiation experiments can provide valuable information when incorporated into experimental end-stations. The instruments can track the volatilization products of beam-sensitive materials, which may ultimately aid researchers in selecting appropriate flux values for conducting experiments. Furthermore, the type of gaseous species released during an irradiation can be monitored directly, which may lead to new insights into the radiolysis and/or heating mechanisms responsible for gas evolution. A survey of several classes of materials exposed to extremes in particle flux is presented to show how RGA instrumentation can be incorporated to qualitatively assess ion-solid interactions in a variety of fields.

Measurement of Charged Current Coherent Pion Production by Neutrinos on Carbon at MINER$$\

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mislivec, Aaron Robert

Neutrino-nucleus coherent pion production is a rare neutrino scattering process where the squared four-momentum transferred to the nucleus is small, a lepton and pion are produced in the forward direction, and the nucleus remains in its initial state. This process is an important background in neutrino oscillation experiments. Measurements of coherent pion production are needed to constrain models which are used to predict coherent pion production in oscillation experiments. This thesis reports measurements of νµ and νµ charged current coherent pion production on carbon for neutrino energies in the range 2 < Eν < 20 GeV. The measurements were mademore » using data from MINERνA, which is a dedicated neutrino-nucleus scattering experiment that uses a fi scintillator tracking detector in the high-intensity NuMI neutrino beam at Fermilab. Coherent interactions were isolated from the data using only model-independent signatures of the reaction, which are a forward muon and pion, no evidence of nuclear breakup, and small four-momentum transfer to the nucleus. The measurements were compared to the coherent pion production model used by oscillation experiments. The data and model agree in the total interaction rate and are similar in the dependence of the interaction rate on the squared four- momentum transferred from the neutrino. The data and model disagree significantly in the pion kinematics. The measured νµ and νµ interaction rates are consistent, which supports model predictions that the neutrino and antineutrino interaction rates are equal.« less

Photochemical versus biological production of methyl iodide during Meteor 55

NASA Astrophysics Data System (ADS)

Richter, U.; Wallace, D.

2003-04-01

The flux of methyl iodide from sea to air represents the largest flux of iodine from the ocean to the atmosphere. Surface water concentrations and hence fluxes are particularly high in tropical regions. This flux may be responsible for the enrichment of iodine in the marine aerosol and may contribute to important processes in the marine boundary layer, including particle formation. Methyl iodide is commonly referred to as a biogenic gas, with both macroalgae and phytoplankton identified as important sources. On the other hand experimental and field data have shown the importance of photochemical production that is not necessarily associated directly with biological activity. During the Meteor cruise 55 along 11°N in the tropical Atlantic Ocean, a series of experiments were conducted to examine the biological vs. photochemical production of methyl iodide. A total of eight separate experiments were conducted. Production of CH3I in quartz glass flasks during 24 hour incubations (dark and natural sunlight) was measured under three experimental treatments: untreated seawater, filtered seawater (0.1 um pore size filter to exclude most phytoplankton and bacteria), and seawater that was poisoned with mercuric chloride. There were two clear findings from these experiments: (1) methyl iodide production was significantly higher in all the incubations that were exposed to the light than in the dark incubations; (2) there was no significant difference between CH3I production under the three experimental treatments. These results argue very strongly for the primary importance of photochemical production of CH3I as opposed to biogenic production at least for the tropical open ocean surface waters. Further experiments are required to investigate the reactants involved, their sources, the wavelength and depth dependence of production, etc. as well as (possibly related) sink processes.

Φ meson production in the forward/backward rapidity region in Cu + Au collisions at s NN = 200 GeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adare, A.; Aidala, C.; Ajitanand, N. N.

2016-02-04

The PHENIX experiment at the Relativistic Heavy Ion Collider has measured φ meson production and its nuclear modification in asymmetric Cu + Au heavy-ion collisions at √ sNN = 200 GeV at both forward Cu-going direction (1.2 < y < 2.2) and backward Au-going direction (-2.2 < y < -1.2) rapidities. The measurements are performed via the dimuon decay channel and reported as a function of the number of participating nucleons, rapidity, and transverse momentum. In the most central events, 0%–20% centrality, the φ meson yield integrated over 1 < p T < 5 GeV/c prefers a smaller value, whichmore » means a larger nuclear modification, in the Cu-going direction compared to the Au-going direction. Finally and additionally, the nuclear-modification factor in Cu + Au collisions averaged over all centrality is measured to be similar to the previous PHENIX result in d + Au collisions for these rapidities.« less

ϕ meson production in the forward/backward rapidity region in Cu + Au collisions at √{sNN}=200 GeV

NASA Astrophysics Data System (ADS)

Adare, A.; Aidala, C.; Ajitanand, N. N.; Akiba, Y.; Akimoto, R.; Alexander, J.; Alfred, M.; Al-Ta'Ani, H.; Andrews, K. R.; Angerami, A.; Aoki, K.; Apadula, N.; Appelt, E.; Aramaki, Y.; Armendariz, R.; Asano, H.; Aschenauer, E. C.; Atomssa, E. T.; Awes, T. C.; Azmoun, B.; Babintsev, V.; Bai, M.; Bai, X.; Bandara, N. S.; Bannier, B.; Barish, K. N.; Bassalleck, B.; Basye, A. T.; Bathe, S.; Baublis, V.; Baumann, C.; Baumgart, S.; Bazilevsky, A.; Beaumier, M.; Beckman, S.; Belmont, R.; Ben-Benjamin, J.; Bennett, R.; Berdnikov, A.; Berdnikov, Y.; Black, D.; Blau, D. S.; Bok, J. S.; Boyle, K.; Brooks, M. L.; Broxmeyer, D.; Bryslawskyj, J.; Buesching, H.; Bumazhnov, V.; Bunce, G.; Butsyk, S.; Campbell, S.; Castera, P.; Chen, C.-H.; Chi, C. Y.; Chiu, M.; Choi, I. J.; Choi, J. B.; Choi, S.; Choudhury, R. K.; Christiansen, P.; Chujo, T.; Chvala, O.; Cianciolo, V.; Citron, Z.; Cole, B. A.; Conesa Del Valle, Z.; Connors, M.; Cronin, N.; Crossette, N.; Csanád, M.; Csörgő, T.; Dairaku, S.; Danley, T. W.; Datta, A.; Daugherity, M. S.; David, G.; Dayananda, M. K.; Deblasio, K.; Dehmelt, K.; Denisov, A.; Deshpande, A.; Desmond, E. J.; Dharmawardane, K. V.; Dietzsch, O.; Ding, L.; Dion, A.; Diss, P. B.; Do, J. H.; Donadelli, M.; D'Orazio, L.; Drapier, O.; Drees, A.; Drees, K. A.; Durham, J. M.; Durum, A.; Efremenko, Y. V.; Engelmore, T.; Enokizono, A.; En'yo, H.; Esumi, S.; Eyser, K. O.; Fadem, B.; Feege, N.; Fields, D. E.; Finger, M.; Finger, M.; Fleuret, F.; Fokin, S. L.; Frantz, J. E.; Franz, A.; Frawley, A. D.; Fukao, Y.; Fusayasu, T.; Gainey, K.; Gal, C.; Gallus, P.; Garg, P.; Garishvili, A.; Garishvili, I.; Ge, H.; Giordano, F.; Glenn, A.; Gong, X.; Gonin, M.; Goto, Y.; Granier de Cassagnac, R.; Grau, N.; Greene, S. V.; Grosse Perdekamp, M.; Gu, Y.; Gunji, T.; Guo, L.; Guragain, H.; Gustafsson, H.-Å.; Hachiya, T.; Haggerty, J. S.; Hahn, K. I.; Hamagaki, H.; Hamblen, J.; Hamilton, H. F.; Han, R.; Han, S. Y.; Hanks, J.; Harper, C.; Hasegawa, S.; Haseler, T. O. S.; Hashimoto, K.; Haslum, E.; Hayano, R.; He, X.; Hemmick, T. K.; Hester, T.; Hill, J. C.; Hollis, R. S.; Holzmann, W.; Homma, K.; Hong, B.; Horaguchi, T.; Hori, Y.; Hornback, D.; Hoshino, T.; Hotvedt, N.; Huang, J.; Huang, S.; Ichihara, T.; Ichimiya, R.; Iinuma, H.; Ikeda, Y.; Imai, K.; Imazu, Y.; Inaba, M.; Iordanova, A.; Isenhower, D.; Ishihara, M.; Isinhue, A.; Issah, M.; Ivanishchev, D.; Iwanaga, Y.; Jacak, B. V.; Jeon, S. J.; Jezghani, M.; Jia, J.; Jiang, X.; John, D.; Johnson, B. M.; Jones, T.; Joo, K. S.; Jouan, D.; Jumper, D. S.; Kamin, J.; Kanda, S.; Kaneti, S.; Kang, B. H.; Kang, J. H.; Kang, J. S.; Kapustinsky, J.; Karatsu, K.; Kasai, M.; Kawall, D.; Kazantsev, A. V.; Kempel, T.; Key, J. A.; Khachatryan, V.; Khandai, P. K.; Khanzadeev, A.; Kijima, K. M.; Kim, B. I.; Kim, C.; Kim, D. J.; Kim, E.-J.; Kim, G. W.; Kim, M.; Kim, Y.-J.; Kim, Y. K.; Kimelman, B.; Kinney, E.; Kiss, Á.; Kistenev, E.; Kitamura, R.; Klatsky, J.; Kleinjan, D.; Kline, P.; Koblesky, T.; Kochenda, L.; Kofarago, M.; Komkov, B.; Konno, M.; Koster, J.; Kotchetkov, D.; Kotov, D.; Král, A.; Krizek, F.; Kunde, G. J.; Kurita, K.; Kurosawa, M.; Kwon, Y.; Kyle, G. S.; Lacey, R.; Lai, Y. S.; Lajoie, J. G.; Lebedev, A.; Lee, D. M.; Lee, G. H.; Lee, J.; Lee, K. B.; Lee, K. S.; Lee, S.; Lee, S. H.; Lee, S. R.; Leitch, M. J.; Leite, M. A. L.; Leitgab, M.; Lewis, B.; Li, X.; Lim, S. H.; Linden Levy, L. A.; Liu, H.; Liu, M. X.; Love, B.; Lynch, D.; Maguire, C. F.; Makdisi, Y. I.; Makek, M.; Manion, A.; Manko, V. I.; Mannel, E.; Mao, Y.; Maruyama, T.; Masui, H.; McCumber, M.; McGaughey, P. L.; McGlinchey, D.; McKinney, C.; Means, N.; Meles, A.; Mendoza, M.; Meredith, B.; Miake, Y.; Mibe, T.; Mignerey, A. C.; Miki, K.; Milov, A.; Mishra, D. K.; Mitchell, J. T.; Miyachi, Y.; Miyasaka, S.; Mizuno, S.; Mohanty, A. K.; Mohapatra, S.; Montuenga, P.; Moon, H. J.; Moon, T.; Morino, Y.; Morreale, A.; Morrison, D. P.; Moskowitz, M.; Motschwiller, S.; Moukhanova, T. V.; Murakami, T.; Murata, J.; Mwai, A.; Nagae, T.; Nagamiya, S.; Nagashima, K.; Nagle, J. L.; Naglis, M.; Nagy, M. I.; Nakagawa, I.; Nakagomi, H.; Nakamiya, Y.; Nakamura, K. R.; Nakamura, T.; Nakano, K.; Nattrass, C.; Netrakanti, P. K.; Newby, J.; Nguyen, M.; Nihashi, M.; Niida, T.; Nishimura, S.; Nouicer, R.; Novák, T.; Novitzky, N.; Nyanin, A. S.; Oakley, C.; O'Brien, E.; Ogilvie, C. A.; Oide, H.; Oka, M.; Okada, K.; Orjuela Koop, J. D.; Osborn, J. D.; Oskarsson, A.; Ouchida, M.; Ozawa, K.; Pak, R.; Pantuev, V.; Papavassiliou, V.; Park, B. H.; Park, I. H.; Park, J. S.; Park, S.; Park, S. K.; Pate, S. F.; Patel, L.; Patel, M.; Pei, H.; Peng, J.-C.; Pereira, H.; Perepelitsa, D. V.; Perera, G. D. N.; Peressounko, D. Yu.; Perry, J.; Petti, R.; Pinkenburg, C.; Pinson, R.; Pisani, R. P.; Proissl, M.; Purschke, M. L.; Qu, H.; Rak, J.; Ramson, B. J.; Ravinovich, I.; Read, K. F.; Reygers, K.; Reynolds, D.; Riabov, V.; Riabov, Y.; Richardson, E.; Rinn, T.; Riveli, N.; Roach, D.; Roche, G.; Rolnick, S. D.; Rosati, M.; Rosendahl, S. S. E.; Rowan, Z.; Rubin, J. G.; Ryu, M. S.; Sahlmueller, B.; Saito, N.; Sakaguchi, T.; Sako, H.; Samsonov, V.; Sano, S.; Sarsour, M.; Sato, S.; Sato, T.; Savastio, M.; Sawada, S.; Schaefer, B.; Schmoll, B. K.; Sedgwick, K.; Seele, J.; Seidl, R.; Sekiguchi, Y.; Sen, A.; Seto, R.; Sett, P.; Sexton, A.; Sharma, D.; Shaver, A.; Shein, I.; Shibata, T.-A.; Shigaki, K.; Shim, H. H.; Shimomura, M.; Shoji, K.; Shukla, P.; Sickles, A.; Silva, C. L.; Silvermyr, D.; Silvestre, C.; Sim, K. S.; Singh, B. K.; Singh, C. P.; Singh, V.; Skolnik, M.; Slunečka, M.; Snowball, M.; Sodre, T.; Solano, S.; Soltz, R. A.; Sondheim, W. E.; Sorensen, S. P.; Sourikova, I. V.; Stankus, P. W.; Steinberg, P.; Stenlund, E.; Stepanov, M.; Ster, A.; Stoll, S. P.; Stone, M. R.; Sugitate, T.; Sukhanov, A.; Sumita, T.; Sun, J.; Sziklai, J.; Takagui, E. M.; Takahara, A.; Taketani, A.; Tanabe, R.; Tanaka, Y.; Taneja, S.; Tanida, K.; Tannenbaum, M. J.; Tarafdar, S.; Taranenko, A.; Tennant, E.; Themann, H.; Thomas, D.; Tieulent, R.; Timilsina, A.; Todoroki, T.; Togawa, M.; Tomášek, L.; Tomášek, M.; Torii, H.; Towell, C. L.; Towell, R.; Towell, R. S.; Tserruya, I.; Tsuchimoto, Y.; Utsunomiya, K.; Vale, C.; van Hecke, H. W.; Vargyas, M.; Vazquez-Zambrano, E.; Veicht, A.; Velkovska, J.; Vértesi, R.; Virius, M.; Vossen, A.; Vrba, V.; Vznuzdaev, E.; Wang, X. R.; Watanabe, D.; Watanabe, K.; Watanabe, Y.; Watanabe, Y. S.; Wei, F.; Wei, R.; Wessels, J.; Whitaker, S.; White, A. S.; White, S. N.; Winter, D.; Wolin, S.; Woody, C. L.; Wright, R. M.; Wysocki, M.; Xia, B.; Xue, L.; Yalcin, S.; Yamaguchi, Y. L.; Yang, R.; Yanovich, A.; Ying, J.; Yokkaichi, S.; Yoo, J. H.; Yoo, J. S.; Yoon, I.; You, Z.; Young, G. R.; Younus, I.; Yu, H.; Yushmanov, I. E.; Zajc, W. A.; Zelenski, A.; Zhou, S.; Zou, L.; Phenix Collaboration

2016-02-01

The PHENIX experiment at the Relativistic Heavy Ion Collider has measured ϕ meson production and its nuclear modification in asymmetric Cu +Au heavy-ion collisions at √{sNN}=200 GeV at both forward Cu-going direction (1.2

Layoffs and tradeoffs: production, quality, and safety demands under the threat of job loss.

PubMed

Probst, Tahira M

2002-07-01

Employees often face a conflict between production targets, quality assurance, and adherence to safety policies. In a time when layoffs are on the rise, it is important to understand the effects of employee job insecurity on these potentially competing demands. A laboratory experiment manipulated the threat of layoffs in a simulated organization and assessed its effect on employee productivity, product quality, and adherence to safety policies. Results suggest that student participants faced with the threat of layoffs were more productive, yet violated more safety rules and produced lower quality outputs, than participants in the control condition. Implications for organizations contemplating layoffs and directions for future research are discussed.

Ion flow experiments in a multipole discharge chamber

NASA Technical Reports Server (NTRS)

Kaufman, H. R.; Robinson, R. S.; Frisa, L. E.

1982-01-01

It has been customary to assume that ions flow nearly equally in all directions from the ion production region within an electron-bombardment discharge chamber. Ion flow measurements in a multipole discharge chamber have shown that this assumption is not true. In general, the electron current through a magnetic field can alter the electron density, and hence the ion density, in such a way that ions tend to be directed away from the region bounded by the magnetic field. When this mechanism is understood, it becomes evident that many past discharge chamber designs have operated with a preferentially directed flow of ions.

Counseling Adult Clients Experiencing Chronic Pain

ERIC Educational Resources Information Center

Burns, Stephanie T.

2010-01-01

Chronic pain affects 35% to 57% of the adult population in the United States and results in billions of dollars spent annually in direct health-care costs and lost productivity. Extensive research confirms the considerable role psychological factors play in the experience and expression of chronic pain. The author discusses implications for…

Rock Climbing: An Experience with Responsibility

ERIC Educational Resources Information Center

Hansen, Ken; Parker, Melissa

2009-01-01

Today's youths seem to be facing more obstacles and receiving less direction than ever before. Rather than just focusing on trouble prevention and deterrence, many youth development and preparation programs are striving to help youths develop the necessary assets, skills, and qualities to become productive and satisfied adults, as well as…

Optimizing Your K-5 Engineering Design Challenge

ERIC Educational Resources Information Center

Coppola, Matthew Perkins; Merz, Alice H.

2017-01-01

Today, elementary school teachers continue to revisit old lessons and seek out new ones, especially in engineering. Optimization is the process by which an existing product or procedure is revised and refined. Drawn from the authors' experiences working directly with students in grades K-5 and their teachers and preservice teachers, the…

Awareness of Verb Subcategorization Probabilities with Polysemous Verbs: The Second Language Situation

ERIC Educational Resources Information Center

Uckun, Berrin

2012-01-01

Different meanings of a verb are associated with different argument structures (subcategorization), which in this study are sentential complements (SC) and direct object (DO) arguments. Interaction between verbal meaning and argument structure is investigated at the production level using polysemous verbs in the absence (Norming Experiment) and…

Homophily through Nonreciprocity: Results of an Experiment

ERIC Educational Resources Information Center

Schaefer, David R.

2012-01-01

This study outlines a new explanation for homophily in social networks that is neither intended nor imposed by constraints on partner choices. Rather, homophily is an endogenous product of the emergent exchange process, in which actors seek high-value partners who reciprocate their gestures. Whereas all actors initially direct exchange toward…

Made to Measure: Early Career Academics in the Canadian University Workplace

ERIC Educational Resources Information Center

Acker, Sandra; Webber, Michelle

2017-01-01

While Canada lacks explicit central directives towards research productivity, academics experience frequent and intense reviews of their research, teaching and service through mechanisms such as elaborate tenure and promotion procedures and annual performance reviews. Given that newer academics are sometimes thought to be especially susceptible to…

Off Limits: Cultural Participation and Art Education

ERIC Educational Resources Information Center

Edge, Nina

2014-01-01

Written from the direct experience of a practitioner, this is an autobiographic paper by a contemporary artist that recounts and explores creative and political activism through contemporary art. This article examines the tensions around status: the status of objects, materials and production methods, and the status of people and their drive to…

Common Learning Objectives for Undergraduate Control Systems Laboratories

ERIC Educational Resources Information Center

Reck, Rebecca M.

2017-01-01

Course objectives, like research objectives and product requirements, help provide clarity and direction for faculty and students. Unfortunately, course and laboratory objectives are not always clearly stated. Without a clear set of objectives, it can be hard to design a learning experience and determine whether students are achieving the intended…

Directing Diplomacy: Creating the Best Experience for Everyone in the Show.

ERIC Educational Resources Information Center

Mulcahy, Lisa

2003-01-01

Discusses the subtle psychological strategies good directors know how to employ with actors. Contends that if a director demonstrates a diplomatic attitude toward every student involved in a production, a perfect working atmosphere is created. Explores diplomacy basics; first impressions; rehearsal problems; personality issues; and talking points.…

Form gene clustering method about pan-ethnic-group products based on emotional semantic

NASA Astrophysics Data System (ADS)

Chen, Dengkai; Ding, Jingjing; Gao, Minzhuo; Ma, Danping; Liu, Donghui

2016-09-01

The use of pan-ethnic-group products form knowledge primarily depends on a designer's subjective experience without user participation. The majority of studies primarily focus on the detection of the perceptual demands of consumers from the target product category. A pan-ethnic-group products form gene clustering method based on emotional semantic is constructed. Consumers' perceptual images of the pan-ethnic-group products are obtained by means of product form gene extraction and coding and computer aided product form clustering technology. A case of form gene clustering about the typical pan-ethnic-group products is investigated which indicates that the method is feasible. This paper opens up a new direction for the future development of product form design which improves the agility of product design process in the era of Industry 4.0.

Analysis of compressive strength in flatwise and edgewise direction to characterize Al-7000 aluminium foam

NASA Astrophysics Data System (ADS)

Sutarno, Soepriyanto, Syoni; Korda, Akhmad A.; Dirgantara, Tatacipta

2015-09-01

The physical mechanical properties of Al-7000 aluminium foam product and processing has been evaluated in this study. The characterization through the compressive testing refers to flatwise direction provided more confident result than edgewise direction. This experiment may correlate with formation of side products of calcia alumina and alumina silica that involved in metal mixture of aluminium foam. These compounds are formed from additional calcium carbonate and silica in the mixture. Calcium carbonate (CaCO3) roles as a blowing agent source of carbon dioxide (CO2). The formation of calcia alumina (CaO.Al2O3) may role to strengthen of cell wall of aluminium foam and to improve the viscosity of melting metal. The Al-7000 aluminium foam indicated a decrease of compressive strength probably due to existence of alumina silica (3Al2O3.SiO2) in the metal mixture.

Observation of an excess of cosmic ray muons of energies 2 TeV from the direction of Cygnus X-3

NASA Technical Reports Server (NTRS)

Battistoni, G.; Bellotti, E.; Bloise, C.; Bologna, G.; Campana, P.; Castagnoli, C.; Castellina, A.; Chiarella, V.; Ciocio, A.; Cundy, D.

1985-01-01

A high flux of muons from the Cygnus X-3 direction has been observed in NUSEX experiment at depths greater than 4600 hg/sq cm s.r. The excess muons show the 4.8 hour modulation in arrival time typical of this source. A study of this modulation was done in order to find the best value of the period and of the period derivative. The muon flux underground from NUSEX and SOUDAN (1800 hg/sq cm) experiments are used to determine the energy spectrum at sea level. The shape and the absolute intensities are found similar to those attributed to gamma rays responsible for production of air showers detected in direction of Cygnus X-3 in the energy range 10 to the 12th power to 10 to the 15th power eV.

A new tracer experiment to estimate the methane emissions from a dairy cow shed using sulfur hexafluoride (SF6)

NASA Astrophysics Data System (ADS)

Marik, Thomas; Levin, Ingeborg

1996-09-01

Methane emission from livestock and agricultural wastes contribute globally more than 30% to the anthropogenic atmospheric methane source. Estimates of this number have been derived from respiration chamber experiments. We determined methane emission rates from a tracer experiment in a modern cow shed hosting 43 dairy cows in their accustomed environment. During a 24-hour period the concentrations of CH4, CO2, and SF6, a trace gas which has been released at a constant rate into the stable air, have been measured. The ratio between SF6 release rate and measured SF6 concentration was then used to estimate the ventilation rate of the stable air during the course of the experiment. The respective ratio between CH4 or CO2 and SF6 concentration together with the known SF6 release rate allows us to calculate the CH4 (and CO2) emissions in the stable. From our experiment we derive a total daily mean CH4 emission of 441 LSTP per cow (9 cows nonlactating), which is about 15% higher than previous estimates for German cows with comparable milk production obtained during respiration chamber experiments. The higher emission in our stable experiment is attributed to the contribution of CH4 release from about 50 m3 of liquid manure present in the cow shed in underground channels. Also, considering measurements we made directly on a liquid manure tank, we obtained an estimate of the total CH4 production from manure: The normalized contribution of methane from manure amounts to 12-30% of the direct methane release of a dairy cow during rumination. The total CH4 release per dairy cow, including manure, is 521-530 LSTP CH4 per day.

Effect of experimental methodology on fasting heat production and the net energy content of corn and soybean meal fed to growing pigs.

PubMed

Liu, Dewen; Jaworski, Neil William; Zhang, Guifeng; Li, Zhongchao; Li, Defa; Wang, Fenglai

2014-01-01

The aim of the three experiments was to evaluated methods to predict fasting heat production (FHP) and to compare methods to determine the net energy (NE) of corn and soybean meal (SBM) fed to growing pigs. To estimate heat production (HP), pigs were housed in respiratory chambers for all experiments. In Experiment 1, six barrows (43.0 ± 1.4 kg body weight [BW]) were fed a Corn-SBM diet for 20 d. The experimental design consisted of following periods: 7 d adaptation, 5 d ad libitum feeding, 3 d feeding at 2 × metabolisable energy (ME) for maintenance (MEm), 3 d feeding at 1 × MEm and 2 d fasting. The FHP was calculated by extrapolating HP measured at the different feeding levels to zero ME intake. The daily FHP [per kg BW(0)(.6)] determined directly after fasting for 24 h and using the regression method was 774 kJ and 694 kJ, respectively. In Experiment 2, 18 barrows (34.3 ± 1.1 kg BW) were randomly allotted to three diets: Diet 1 contained 97.5% corn (direct NE determination of corn); diets 2 and 3 contained 25 % and 15% SBM at the expense of corn, respectively, and were used to calculate the NE of corn by difference. The NE of corn determined directly (13.21 MJ/kg DM) and by difference (13.69 MJ/kg DM) was not different. In Experiment 3, 24 barrows (36.2 ± 1.4 kg BW) were randomly allotted to four diets to determine the effects of different basal diets on the NE content of SBM. The diets were: Basal diet 1 (97.5% corn), Test diet 1 (15% SBM at the expense of corn), Basal diet 2 (contained 72.5% corn and 25% SBM) and Test diet 2 (58% corn and 39.5% SBM). These diets were used to determine the NE of SBM using the Corn-basal diet or the Corn-SBM-basal diet, respectively. It was shown that the estimated NE of SBM did not depend on the used diet (10.04 MJ/kg and 10.62 MJ/kg DM for Basal diet 1 and 2, respectively). In summary, using the regression method to determine FHP results in lower FHP than the fasting method. There was no difference observed in the NE of corn determined directly or by difference, and different basal diets did not affect the NE of SBM.

Teaching children about good health? Halo effects in child-directed advertisements for unhealthy food.

PubMed

Harris, J L; Haraghey, K S; Lodolce, M; Semenza, N L

2018-04-01

Food companies often use healthy lifestyle messages in child-directed advertising, raising public health concerns about health halo effects for nutrient-poor food/drinks. Examine effects of health messages promoting nutrient-poor foods in child-directed advertising. Randomized controlled experiment (N = 138). Children (7-11 years) viewed three child-friendly commercials in one of three conditions: (1) health halo (unfamiliar nutrient-poor food/drink ads with healthy messages); (2) nutrient-poor food/drink ads with other messages and (3) healthy food/drink ads. They rated the commercials and advertised products, provided attitudes about exercise and nutrition and consumed and rated healthy and unhealthy snack foods. Children in the health halo condition rated the advertised nutrient-poor products as significantly healthier compared with children in other conditions (p = .003), but the other commercials did not affect children's attitudes about other advertised products (p's > .50). Child age, gender or TV viewing habits did not significantly predict their ratings (p's > .18). There was no evidence that healthy lifestyle messages and/or healthy food commercials improved children's attitudes about nutrition, exercise or healthy snack consumption. Promoting healthy lifestyle messages in child-directed commercials for nutrient-poor food/drinks likely benefits brands by increasing products' perceived healthfulness, but these ads are unlikely to positively affect children's attitudes about health and nutrition. © 2017 World Obesity Federation.

Observation of Transverse Spin-Dependent Azimuthal Correlations of Charged Pion Pairs in p↑+p at √{s }=200 GeV

NASA Astrophysics Data System (ADS)

Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Averichev, G. S.; Banerjee, A.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Bouchet, J.; Brandin, A. V.; Bunzarov, I.; Burton, T. P.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Cervantes, M. C.; Chakaberia, I.; Chaloupka, P.; Chang, Z.; Chattopadhyay, S.; Chen, J. H.; Chen, X.; Cheng, J.; Cherney, M.; Christie, W.; Contin, G.; Crawford, H. J.; Das, S.; De Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; di Ruzza, B.; Didenko, L.; Dilks, C.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Eppley, G.; Esha, R.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Federic, P.; Fedorisin, J.; Feng, Z.; Filip, P.; Fisyak, Y.; Flores, C. E.; Fulek, L.; Gagliardi, C. A.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, S.; Gupta, A.; Guryn, W.; Hamad, A.; Hamed, A.; Haque, R.; Harris, J. W.; He, L.; Heppelmann, S.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Hofman, D. J.; Horvat, S.; Huang, B.; Huang, X.; Huang, H. Z.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jang, H.; Jiang, K.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Khan, Z. H.; Kikola, D. P.; Kisel, I.; Kisiel, A.; Kochenda, L.; Koetke, D. D.; Kollegger, T.; Kosarzewski, L. K.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kulakov, I.; Kumar, L.; Kycia, R. A.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; Li, X.; Li, C.; Li, W.; Li, Z. M.; Li, Y.; Li, X.; Lisa, M. A.; Liu, F.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Ma, Y. G.; Ma, G. L.; Ma, L.; Ma, R.; Magdy, N.; Majka, R.; Manion, A.; Margetis, S.; Markert, C.; Masui, H.; Matis, H. S.; McDonald, D.; Meehan, K.; Minaev, N. G.; Mioduszewski, S.; Mohanty, B.; Mondal, M. M.; Morozov, D.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nigmatkulov, G.; Nogach, L. V.; Noh, S. Y.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Okorokov, V.; Olvitt, D.; Page, B. S.; Pak, R.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlik, B.; Pei, H.; Perkins, C.; Peterson, A.; Pile, P.; Planinic, M.; Pluta, J.; Poljak, N.; Poniatowska, K.; Porter, J.; Posik, M.; Poskanzer, A. M.; Pruthi, N. K.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Roy, A.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, M. K.; Sharma, B.; Shen, W. Q.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Sikora, R.; Simko, M.; Skoby, M. J.; Smirnov, D.; Smirnov, N.; Song, L.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stepanov, M.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sumbera, M.; Summa, B.; Sun, X.; Sun, Z.; Sun, X. M.; Sun, Y.; Surrow, B.; Svirida, N.; Szelezniak, M. A.; Tang, A. H.; Tang, Z.; Tarnowsky, T.; Tawfik, A. N.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Tripathy, S. K.; Trzeciak, B. A.; Tsai, O. D.; Ullrich, T.; Underwood, D. G.; Upsal, I.; Van Buren, G.; van Nieuwenhuizen, G.; Vandenbroucke, M.; Varma, R.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Viyogi, Y. P.; Vokal, S.; Voloshin, S. A.; Vossen, A.; Wang, G.; Wang, Y.; Wang, F.; Wang, Y.; Wang, H.; Wang, J. S.; Webb, J. C.; Webb, G.; Wen, L.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y. F.; Xiao, Z. G.; Xie, W.; Xin, K.; Xu, Q. H.; Xu, Z.; Xu, H.; Xu, N.; Xu, Y. F.; Yang, Q.; Yang, Y.; Yang, S.; Yang, Y.; Yang, C.; Ye, Z.; Yepes, P.; Yi, L.; Yip, K.; Yoo, I.-K.; Yu, N.; Zbroszczyk, H.; Zha, W.; Zhang, X. P.; Zhang, J.; Zhang, Y.; Zhang, J.; Zhang, J. B.; Zhang, S.; Zhang, Z.; Zhao, J.; Zhong, C.; Zhou, L.; Zhu, X.; Zoulkarneeva, Y.; Zyzak, M.; STAR Collaboration

2015-12-01

We report the observation of transverse polarization-dependent azimuthal correlations in charged pion pair production with the STAR experiment in p↑+p collisions at RHIC. These correlations directly probe quark transversity distributions. We measure signals in excess of 5 standard deviations at high transverse momenta, at high pseudorapidities η >0.5 , and for pair masses around the mass of the ρ meson. This is the first direct transversity measurement in p +p collisions.

How important is local food to organic-minded consumers?

PubMed

Hempel, Corinna; Hamm, Ulrich

2016-01-01

The study deals with German consumers' attitudes towards organic food and local food, their food purchase behaviour and their personal characteristics. The purpose is to investigate the differences in attitudes and willingness-to-pay values between consumers who consider the organic production of food (very) important and those who consider it less important. This study combines a consumer survey with an in-store, discrete choice experiment. In the analysis, findings from the consumer survey were related to the choices made by consumers in the experiment. Consumers' preferences and willingness-to-pay values were estimated through random parameter logit modelling. Organic-minded consumers (i.e. those who regarded organic food production as (very) important in the survey) have stronger preferences and estimated willingness-to-pay values for organic as well as local products. Locally produced food, as opposed to food from neighbouring countries or non-EU countries, is preferred over organically produced food by both consumer groups which demonstrates that organic-minded consumers do not only consider organic food production as important, but also value local food production in a purchase situation. Hence, it can be assumed that local food production complements organic food production for the group of organic-minded consumers. This contribution is the first study dealing with local and organic food purchase behaviour in Germany that examines four different products and is carried out in rural as well as urban locations in four different regions. Due to the application of a choice experiment including no-choice options and binding purchase decisions, the results are expected to be closer to real purchase situations than results of direct questioning and choice experiments in online applications. Copyright © 2015 Elsevier Ltd. All rights reserved.

The effect of ethanol concentration on the direct ethanol fuel cell performance and products distribution: A study using a single fuel cell/attenuated total reflectance - Fourier transform infrared spectroscopy

NASA Astrophysics Data System (ADS)

Assumpção, M. H. M. T.; Nandenha, J.; Buzzo, G. S.; Silva, J. C. M.; Spinacé, E. V.; Neto, A. O.; De Souza, R. F. B.

2014-05-01

The effect of ethanol concentration on the direct ethanol fuel cell (DEFC) performance and products distribution were studied in situ using a single fuel cell/ATR-FTIR setup. The experiments were performed at 80 °C using commercial Pt3Sn/C as anodic catalyst and the concentrations of ethanol solution were varied from 0.1 to 2.0 mol L-1. An increase in power density was observed with the increase of ethanol concentration to 1.0 mol L-1, while the band intensities analysis in the FTIR spectra revealed an increase of acetic acid/acetaldehyde ratio with the increase of ethanol concentration. Also, from FTIR spectra results, it could be concluded that the acetic acid production follow parallel mechanisms; that is, it does not require the presence of acetaldehyde as an intermediate.

Nonenzymatic oligomerization reactions on templates containing inosinic acid or diaminopurine nucleotide residues

NASA Technical Reports Server (NTRS)

Kozlov, I. A.; Orgel, L. E.; Bada, J. L. (Principal Investigator)

1999-01-01

The template-directed oligomerization of nucleoside-5'-phosphoro-2-methyl imidazolides on standard oligonucleotide templates has been studied extensively. Here, we describe experiments with templates in which inosinic acid (I) is substituted for guanylic acid, or 2,6-diaminopurine nucleotide (D) for adenylic acid. We find that the substitution of I for G in a template is strongly inhibitory and prevents any incorporation of C into internal positions in the oligomeric products of the reaction. The substitution of D for A, on the contrary, leads to increased incorporation of U into the products. We found no evidence for the template-directed facilitation of oligomerization of A or I through A-I base pairing. The significance of these results for prebiotic chemistry is discussed.

Kinetics of carbon clustering in detonation of high explosives: Does theory match experiment?

NASA Astrophysics Data System (ADS)

Velizhanin, Kirill; Watkins, Erik; Dattelbaum, Dana; Gustavsen, Richard; Aslam, Tariq; Podlesak, David; Firestone, Millicent; Huber, Rachel; Ringstrand, Bryan; Willey, Trevor; Bagge-Hansen, Michael; Hodgin, Ralph; Lauderbach, Lisa; van Buuren, Tony; Sinclair, Nicholas; Rigg, Paulo; Seifert, Soenke; Gog, Thomas

2017-06-01

Chemical reactions in detonation of carbon-rich high explosives yield carbon clusters as major constituents of the products. Efforts to model carbon clustering as a diffusion-limited irreversible coagulation of carbon clusters go back to the seminal paper by Shaw and Johnson. However, first direct experimental observations of the kinetics of clustering yielded cluster growth one to two orders of magnitude slower than theoretical predictions. Multiple efforts were undertaken to test and revise the basic assumptions of the model in order to achieve better agreement with experiment. We discuss our very recent direct experimental observations of carbon clustering dynamics and demonstrate that these new results are in much better agreement with the modified Shaw-Johnson model. The implications of this much better agreement on our present understanding of detonation carbon clustering processes and possible ways to increase the agreement between theory and experiment even further are discussed.

Rapid detection of hazardous chemicals in textiles by direct analysis in real-time mass spectrometry (DART-MS).

PubMed

Antal, Borbála; Kuki, Ákos; Nagy, Lajos; Nagy, Tibor; Zsuga, Miklós; Kéki, Sándor

2016-07-01

Residues of chemicals on clothing products were examined by direct analysis in real-time (DART) mass spectrometry. Our experiments have revealed the presence of more than 40 chemicals in 15 different clothing items. The identification was confirmed by DART tandem mass spectrometry (MS/MS) experiments for 14 compounds. The most commonly detected hazardous substances were nonylphenol ethoxylates (NPEs), phthalic acid esters (phthalates), amines released by azo dyes, and quinoline derivates. DART-MS was able to detect NPEs on the skin of the person wearing the clothing item contaminated by NPE residuals. Automated data acquisition and processing method was developed and tested for the recognition of NPE residues thereby reducing the analysis time.

How reading differs from object naming at the neuronal level.

PubMed

Price, C J; McCrory, E; Noppeney, U; Mechelli, A; Moore, C J; Biggio, N; Devlin, J T

2006-01-15

This paper uses whole brain functional neuroimaging in neurologically normal participants to explore how reading aloud differs from object naming in terms of neuronal implementation. In the first experiment, we directly compared brain activation during reading aloud and object naming. This revealed greater activation for reading in bilateral premotor, left posterior superior temporal and precuneus regions. In a second experiment, we segregated the object-naming system into object recognition and speech production areas by factorially manipulating the presence or absence of objects (pictures of objects or their meaningless scrambled counterparts) with the presence or absence of speech production (vocal vs. finger press responses). This demonstrated that the areas associated with speech production (object naming and repetitively saying "OK" to meaningless scrambled pictures) corresponded exactly to the areas where responses were higher for reading aloud than object naming in Experiment 1. Collectively the results suggest that, relative to object naming, reading increases the demands on shared speech production processes. At a cognitive level, enhanced activation for reading in speech production areas may reflect the multiple and competing phonological codes that are generated from the sublexical parts of written words. At a neuronal level, it may reflect differences in the speed with which different areas are activated and integrate with one another.

Effects of consumer motives on search behavior using internet advertising.

PubMed

Yang, Kenneth C C

2004-08-01

Past studies on uses and gratifications theory suggested that consumer motives affect how they will use media and media contents. Recent advertising research has extended the theory to study the use of Internet advertising. The current study explores the effects of consumer motives on their search behavior using Internet advertising. The study employed a 2 by 2 between-subjects factorial experiment design. A total of 120 subjects were assigned to an experiment condition that contains an Internet advertisement varying by advertising appeals (i.e., rational vs. emotional) and product involvement levels (high vs. low). Consumer search behavior (measured by the depth, breadth, total amount of search), demographics, and motives were collected by post-experiment questionnaires. Because all three dependent variables measuring search behavior were conceptually related to each other, MANCOVA procedures were employed to examine the moderating effects of consumer motives on the dependent variables in four product involvement-advertising appeal conditions. Results indicated that main effects for product involvements and advertising appeals were statistically significant. Univariate ANOVA also showed that advertising appeals and product involvement levels influenced the total amount of search. Three-way interactions among advertising appeals, product involvement levels, and information motive were also statistically significant. Implications and future research directions are discussed.

Simulations and measurements of hot-electron generation driven by the multibeam two-plasmon-decay instability

NASA Astrophysics Data System (ADS)

Follett, R. K.; Myatt, J. F.; Shaw, J. G.; Michel, D. T.; Solodov, A. A.; Edgell, D. H.; Yaakobi, B.; Froula, D. H.

2017-10-01

Multibeam experiments relevant to direct-drive inertial confinement fusion show the importance of nonlinear saturation mechanisms in the common-wave two-plasmon-decay (TPD) instability. Planar-target experiments on the OMEGA laser used hard x-ray measurements to study the influence of the linear common-wave growth rate on TPD-driven hot-electron production in two drive-beam configurations and over a range of overlapped laser intensities from 3.6 to 15.2 × 1014 W/cm2. The beam configuration with the larger linear common-wave growth rate had a lower intensity threshold for the onset of hot-electron production, but the linear growth rate made no significant impact on hot-electron production at high intensities. The experiments were modeled in 3-D using a hybrid code LPSE (laser plasma simulation environment) that combines a wave solver with a particle tracker to self-consistently calculate the electron velocity distribution and evolve electron Landau damping. Good quantitative agreement was obtained between the simulated and measured hot-electron distributions using a novel technique to account for macroscopic spatial and temporal variations that were present in the experiments.

Simulations and measurements of hot-electron generation driven by the multibeam two-plasmon-decay instability

DOE PAGES

Follett, R. K.; Myatt, J. F.; Shaw, J. G.; ...

2017-10-30

We report that multiple-beam experiments relevant to direct-drive inertial confinement fusion show the importance of nonlinear saturation mechanisms in the common-wave two-plasmon-decay (TPD) instability. Planar target experiments on the OMEGA laser used hard-x-ray measurements to study the influence of the linear common-wave growth rate on TPD driven hot-electron production in two drive beam configurations and over a range of overlapped laser intensities from 3.6 to 15.2 x 10 14 W/cm 2. The beam configuration with the larger linear common-wave growth rate had a lower intensity threshold for the onset of hot-electron production, but the linear growth rate did not havemore » a significant impact on hot-electron production at high intensities. The experiments were modeled in 3-D using a hybrid code (LPSE) that combines a wave solver with a particle tracker to self-consistently calculate the electron velocity distribution and evolve electron Landau damping. Finally, good quantitative agreement was obtained between the simulated and measured hotel-electron distributions using a novel technique to account for macroscopic spatial and temporal variations that are present in the experiments.« less

Simulations and measurements of hot-electron generation driven by the multibeam two-plasmon-decay instability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Follett, R. K.; Myatt, J. F.; Shaw, J. G.

We report that multiple-beam experiments relevant to direct-drive inertial confinement fusion show the importance of nonlinear saturation mechanisms in the common-wave two-plasmon-decay (TPD) instability. Planar target experiments on the OMEGA laser used hard-x-ray measurements to study the influence of the linear common-wave growth rate on TPD driven hot-electron production in two drive beam configurations and over a range of overlapped laser intensities from 3.6 to 15.2 x 10 14 W/cm 2. The beam configuration with the larger linear common-wave growth rate had a lower intensity threshold for the onset of hot-electron production, but the linear growth rate did not havemore » a significant impact on hot-electron production at high intensities. The experiments were modeled in 3-D using a hybrid code (LPSE) that combines a wave solver with a particle tracker to self-consistently calculate the electron velocity distribution and evolve electron Landau damping. Finally, good quantitative agreement was obtained between the simulated and measured hotel-electron distributions using a novel technique to account for macroscopic spatial and temporal variations that are present in the experiments.« less

Experiments on water/melt explosions, nature of products, and models of dispersal

NASA Technical Reports Server (NTRS)

Sheridan, M. F.; Wohletz, K. H.

1984-01-01

Experiments were carried out in a steel pressure device using controlled amounts of water and thermite melt to examine the mechanical energy released on explosive mixing following the initial contact of the two materials. An experimental design was used to allow the direct calculation of the mechanical energy by the dynamic lift of the device as recorded both optically and physically. A large number of experiments were run to accurately determine the optimum mixture of water and melt for the conversion of thermal to mechanical energy. The maximum efficiency observed was about 12% at a water/thermite mass ratio of 0.50. These experiments are the basis for the development of models of hydroexplosions and melt fragmentation. Particles collected from the experimental products are similar in size and shape to pyroclasts produced by much larger hydrovolcanic explosions. Melt rupture at optimum ratios produces very fine particles whereas rupture at high or low water/melt ratios produces large melt fragments. Grain surface textures in the experimental products are also related to the water/melt ratio and the mechanism of explosive mixing. It is thus possible to have qualitative information about the nature of the explosion from the sizes and shapes of the fragments produced.

Mechanisms of inhibition by fluoride of urease activities of cell suspensions and biofilms of Staphylococcus epidermidis, Streptococcus salivarius, Actinomyces naeslundii and of dental plaque.

PubMed

Barboza-Silva, E; Castro, A C D; Marquis, R E

2005-12-01

Fluoride is known to be a potent inhibitor of bacterial ureases and can also act in the form of hydrofluoric acid as a transmembrane proton conductor to acidify the cytoplasm of intact cells with possible indirect, acid inhibition of urease. Our research objectives were to assess the inhibitory potencies of fluoride for three urease-positive bacteria commonly found in the mouth and to determine the relative importance of direct and indirect inhibition of ureases for overall inhibition of intact cells or biofilms. The experimental design involved intact bacteria in suspensions, mono-organism biofilms, cell extracts, and dental plaque. Standard enzymatic assays for ammonia production from urea were used. We found that ureolysis by cells in suspensions or mono-organism biofilms of Staphylococcus epidermidis, Streptococcus salivarius or Actinomyces naeslundii was inhibited by fluoride at plaque levels of 0.1-0.5 mm in a pH-dependent manner. The results of experiments with the organic weak acids indomethacin and capric acid, which do not directly inhibit urease enzyme, indicated that weak-acid effects leading to cytoplasmic acidification are also involved in fluoride inhibition. However, direct fluoride inhibition of urease appeared to be the major mechanism for reduction in ureolytic activity in acid environments. Results of experiments with freshly harvested supragingival dental plaque indicated responses to fluoride similar to those of S. salivarius with pH-dependent fluoride inhibition and both direct and indirect inhibition of urease. Fluoride can act to diminish alkali production from urea by oral bacteria through direct and indirect mechanisms.

Biochar assisted thermophilic co-digestion of food waste and waste activated sludge under high feedstock to seed sludge ratio in batch experiment.

PubMed

Li, Qian; Xu, Manjuan; Wang, Gaojun; Chen, Rong; Qiao, Wei; Wang, Xiaochang

2018-02-01

Batch experiments were conducted using biochar (BC) to promote stable and efficient methane production from thermophilic co-digestion of food waste (FW) and waste activated sludge (WAS) at feedstock/seed sludge (F/S) ratios of 0.25, 0.75, 1.5, 2.25, and 3. The results showed that the presence of BC dramatically shortened the lag time of methane production and increased the methane production rate with increased organic loading. The higher buffer capacity and large specific surface area of BC promoted microorganism growth and adaption to VFAs accumulation. Additionally, the electron exchange in syntrophic oxidation of butyrate and acetate as intermediate products was significantly facilitated by BC possibly due to the selective succession of bacteria and methanogens which may have participated in direct interspecies electron transfer, in contrast with the control group with low-efficient electron ferried between syntrophic oxidizers and methanogens using hydrogen as the electron carrier. Copyright © 2017 Elsevier Ltd. All rights reserved.

Effects of varying food and density on reproduction in Diaptomus clavipes Schacht

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cooney, J.D.; Gehrs, C.W.; Bunting, D.L. II

1978-05-01

Experiments were conducted to determine the effects of varying food and density on the egg production of the calanoid copepod, Diaptomus clavipes Schacht. These experiments were performed at both the population and organismic level. An attempt was also made to evaluate the feasibility of using a flow-through system to study the effects of various environmental factors on egg production in copepods. It was found that food supply was an important factor determining rate of clutch production, number of eggs per clutch, and size of individual eggs. As food supply decreased, both the rate of clutch production and the number ofmore » eggs per clutch decreased, but the size of individual eggs increased. During periods of extreme food shortage, not only did egg production cease, but also the production of spermatophores by males. When starved females were placed under optimum feeding conditions, they produced eggs within a few days and were producing maximally within two weeks. Egg production in the flow-through system was reduced, due primarily to food shortage. The trout chow solution which was used as food was inadequate because it was not directly utilized by the copepods.« less

Transcriptional profiling identifies differentially expressed genes in developing turkey skeletal muscle

PubMed Central

2011-01-01

Background Skeletal muscle growth and development from embryo to adult consists of a series of carefully regulated changes in gene expression. Understanding these developmental changes in agriculturally important species is essential to the production of high quality meat products. For example, consumer demand for lean, inexpensive meat products has driven the turkey industry to unprecedented production through intensive genetic selection. However, achievements of increased body weight and muscle mass have been countered by an increased incidence of myopathies and meat quality defects. In a previous study, we developed and validated a turkey skeletal muscle-specific microarray as a tool for functional genomics studies. The goals of the current study were to utilize this microarray to elucidate functional pathways of genes responsible for key events in turkey skeletal muscle development and to compare differences in gene expression between two genetic lines of turkeys. To achieve these goals, skeletal muscle samples were collected at three critical stages in muscle development: 18d embryo (hyperplasia), 1d post-hatch (shift from myoblast-mediated growth to satellite cell-modulated growth by hypertrophy), and 16wk (market age) from two genetic lines: a randombred control line (RBC2) maintained without selection pressure, and a line (F) selected from the RBC2 line for increased 16wk body weight. Array hybridizations were performed in two experiments: Experiment 1 directly compared the developmental stages within genetic line, while Experiment 2 directly compared the two lines within each developmental stage. Results A total of 3474 genes were differentially expressed (false discovery rate; FDR < 0.001) by overall effect of development, while 16 genes were differentially expressed (FDR < 0.10) by overall effect of genetic line. Ingenuity Pathways Analysis was used to group annotated genes into networks, functions, and canonical pathways. The expression of 28 genes involved in extracellular matrix regulation, cell death/apoptosis, and calcium signaling/muscle function, as well as genes with miscellaneous function was confirmed by qPCR. Conclusions The current study identified gene pathways and uncovered novel genes important in turkey muscle growth and development. Future experiments will focus further on several of these candidate genes and the expression and mechanism of action of their protein products. PMID:21385442

Determination of Caffeine in Beverages by Capillary Zone Electrophoresis: An Experiment for the Undergraduate Analytical Laboratory

NASA Astrophysics Data System (ADS)

Conte, Eric D.; Barry, Eugene F.; Rubinstein, Harry

1996-12-01

Certain individuals may be sensitive to specific compounds in comsumer products. It is important to quantify these analytes in food products in order to monitor their intake. Caffeine is one such compound. Determination of caffeine in beverages by spectrophotometric procedures requires an extraction procedure, which can prove time-consuming. Although the corresponding determination by HPLC allows for a direct injection, capillary zone electrophoresis provides several advantages such as extremely low solvent consumption, smaller sample volume requirements, and improved sensitivity.

Charge and transverse momentum correlations in deep inelastic muon-proton scattering

NASA Astrophysics Data System (ADS)

Arneodo, M.; Arvidson, A.; Aubert, J. J.; Badelek, B.; Beaufays, J.; Bee, C.; Benchouk, C.; Berghoff, G.; Bird, I.; Blurn, D.; Bohm, E.; de Bouard, X.; Brasse, F. W.; Braun, H.; Broll, C.; Brown, S.; Hruck, H.; Calen, H.; Chima, J. S.; Ciborowski, J.; Clifft, R.; Coignet, G.; Combley, F.; Coughlan, J.; Agostini, G. D'; Dahlgren, S.; Dengler, F.; Derado, I.; Dreyer, T.; Drees, J.; Düren, M.; Eckardt, V.; Edwards, A.; Adwards, M.; Ernst, T.; Eszes, G.; Favier, J.; Ferrero, M. I.; Figiel, J.; Flauger, W.; Foster, J.; Gabathuler, E.; Gajewski, J.; Gamet, R.; Gayler, J.; Geddes, N.; Grafström, P.; Grard, F.; Haas, J.; Hagberg, E.; Hasert, F. J.; Hayman, P.; Heusse, P.; Jaffré, M.; Jacholkowska, A.; Janata, F.; Jancso, G.; Johnson, A. S.; Kabuss, E. M.; Kellner, G.; Korbel, V.; Krüger, J.; Kullander, S.; Landgraf, U.; Lanske, D.; Loken, J.; Long, K.; Maire, M.; Malecki, P.; Manz, A.; Maselli, S.; Mohr, W.; Montanet, F.; Montgomery, H. E.; Nagy, E.; Nassalski, J.; Norton, P. R.; Oakham, F. G.; Osborne, A. M.; Pascaud, C.; Pawlik, B.; Payre, P.; Peroni, C.; Pessard, H.; Pettingale, J.; Pietrzyk, B.; Poensgen, B.; Pötsch, M.; Renton, P.; Ribarics, P.; Rith, K.; Rondio, E.; Scheer, M.; Schlagböhmer, A.; Schiemann, H.; Schmitz, N.; Schneegans, M.; Scholz, M.; Schröder, T.; Schouten, M.; Schultze, K.; Sloan, T.; Stier, H. E.; Studt, M.; Taylor, G. N.; Thénard, J. M.; Thompson, J. C.; de La Torre, A.; Toth, J.; Urban, L.; Wallucks, W.; Whalley, M.; Wheeler, S.; Williams, W. S. C.; Wimpenny, S.; Windmolders, R.; Wolf, G.

1986-09-01

Correlations between charged hadrons are investigated in a 280 GeV muon-proton scattering experiment. Although most of the observed particles are decay products it is shown that the correlations found originate in the fragmentation process and are not due simply to resonance production. Correlations are demonstrated between hadrons close in rapidity with respect to their charges and to the directions of their momentum components perpendicular to the virtual photon axis. Such short range correlations are predicted by the standard hadronization models.

Phonological Planning during Sentence Production: Beyond the Verb.

PubMed

Schnur, Tatiana T

2011-01-01

The current study addresses the extent of phonological planning during spontaneous sentence production. Previous work shows that at articulation, phonological encoding occurs for entire phrases, but encoding beyond the initial phrase may be due to the syntactic relevance of the verb in planning the utterance. I conducted three experiments to investigate whether phonological planning crosses multiple grammatical phrase boundaries (as defined by the number of lexical heads of phrase) within a single phonological phrase. Using the picture-word interference paradigm, I found in two separate experiments a significant phonological facilitation effect to both the verb and noun of sentences like "He opens the gate." I also altered the frequency of the direct object and found longer utterance initiation times for sentences ending with a low-frequency vs. high-frequency object offering further support that the direct object was phonologically encoded at the time of utterance initiation. That phonological information for post-verbal elements was activated suggests that the grammatical importance of the verb does not restrict the extent of phonological planning. These results suggest that the phonological phrase is unit of planning, where all elements within a phonological phrase are encoded before articulation. Thus, consistent with other action sequencing behavior, there is significant phonological planning ahead in sentence production.

Confirmation of the Decay of 283112 and First Indication for Hg-like Behavior of Element 112

NASA Astrophysics Data System (ADS)

Eichler, R.; Aksenov, N. V.; Belozerov, A. V.; Bozhikov, G. A.; Chepigin, V. I.; Dressler, R.; Dmitriev, S. N.; Gäggeler, H. W.; Gorshkov, V. A.; Haenssler, F.; Itkis, M. G.; Lebedev, V. Ya.; Laube, A.; Malyshev, O. N.; Oganessian, Yu. Ts.; Petruschkin, O. V.; Piguet, D.; Rasmussen, P.; Shishkin, S. V.; Shutov, A. V.; Svirikhin, A. I.; Tereshatov, E. E.; Vostokin, G. K.; Wegrzecki, M.; Yeremin, A. V.

2007-05-01

Two gas phase adsorption chemistry experiments aimed at the chemical characterization of element 112 using its isotope 283112 have been performed at the Flerov Laboratory for Nuclear Reactions (FLNR) Dubna, Russia. The applied Insitu-Volatilization and On-line Detection (IVO) technique is a thermochromatographic system combining the determination of the deposition temperature of volatile elements on a surface along a temperature gradient with an efficient detection of the deposited species by event-by-event alpha and SF-fragment spectroscopy. Two possibilities to produce the isotope 283112 were used: 1.) the direct production reaction 238U( 48Ca,3n) 283112; 2.) the reaction 242Pu( 48Ca,3n), where the primary product 287114, decays via alpha emission to 283112 with a half-life of 0.5 s. The chemistry experiments were aimed at a chemical identification of 283112 and an independent confirmation of its decay properties. In the direct reaction no decays related to 283112 were observed. However, two decay chains unambiguously attributed to the decay of 283112 were observed using the second production path. Previously reported observation of 283112 and 279Ds and their decay properties were confirmed. From its thermochromatorgaphic deposition first thermochemical data were deduced for element 112, unveiling it as a typical group 12 element.

Neurophysiological evidence that perceptions of fluency produce mere exposure effects.

PubMed

Leynes, P Andrew; Addante, Richard J

2016-08-01

Recent exposure to people or objects increases liking ratings, the "mere exposure effect" (Zajonc in American Psychologist, 35, 117-123, 1968), and an increase in processing fluency has been identified as a potential mechanism for producing this effect. This fluency hypothesis was directly tested by altering the trial-by-trial image clarity (i.e., fluency) while Event-Related Potentials (ERPs) were recorded. In Experiment 1, clarity was altered across two trial blocks that each had homogenous trial-by-trial clarity, whereas clarity varied randomly across trials in Experiment 2. Blocking or randomizing image clarity across trials was expected to produce different levels of relative fluency and alter mere exposure effects. The mere exposure effect (i.e., old products liked more than new products) was observed when stimulus clarity remained constant across trials, and clear image ERPs were more positive than blurry image ERPs. Importantly, these patterns were reversed when clarity varied randomly across test trials, such that participants liked clear images more than blurry (i.e., no mere exposure effect) and clear image ERPs were more negative than blurry image ERPs. The findings provide direct experimental support from both behavioral and electrophysiological measures that, in some contexts, mere exposure is the product of top-down interpretations of fluency.

Yield strength of Cu and an engineered material of Cu with 1% Pb

NASA Astrophysics Data System (ADS)

Buttler, William; Gray, George, III; Fensin, Saryu; Grover, Mike; Stevens, Gerald; Stone, Joseph; Turley, William

2015-06-01

To study the effects of engineered elastic-plastic yield on the mass-ejection from shocked materials we fielded explosively driven Cu and CuPb experiments. The Cu and CuPb experiments fielded fully annealed disks in contact with PBX 9501; the CuPb was extruded with 1% Pb that aggregates at the Cu grain boundaries. The elastic-plastic yield strength is explored as a difference of ejecta production of CuPb versus Cu, where the ejecta production of solid materials ties directly to the surface perturbation geometries of wavelengths (fixed at 65 μm) and amplitudes (which were varied). We observed that the Cu performs as expected, with ejecta turning on at the previously observed yield threshold, but the CuPb ejects mass in much larger quantities, at much lower wavenumber (k = 2 π/ λ) amplitude (h) products (kh), implying a reduced elastic-plastic yield stress of the engineered material, CuPb.

Evidence for Neutral-Current Diffractive π 0 Production from Hydrogen in Neutrino Interactions on Hydrocarbon

DOE PAGES

Wolcott, J.; Aliaga, L.; Altinok, O.; ...

2016-09-01

Here, the MINERvA experiment observes an excess of events containing electromagnetic showers relative to the expectation from Monte Carlo simulations in neutral-current neutrino interactions with mean beam energy of 4.5 GeV on a hydrocarbon target. The excess is characterized and found to be consistent with neutral-current π 0 production with a broad energy distribution peaking at 7 GeV and a total cross section of 0.26more » $$\\pm$$ 0.02 (stat) $$\\pm$$ 0.08 (sys) x $$10^{-39} cm^{2}$$. The angular distribution, electromagnetic shower energy, and spatial distribution of the energy depositions of the excess are consistent with expectations from neutrino neutral-current diffractive neutral pion production from hydrogen in the hydrocarbon target. These data comprise the first direct experimental observation and constraint for a reaction that poses an important background process in neutrino oscillation experiments searching for $$\

Cyanobacterial PHA Production—Review of Recent Advances and a Summary of Three Years’ Working Experience Running a Pilot Plant

PubMed Central

Troschl, Clemens; Meixner, Katharina; Drosg, Bernhard

2017-01-01

Cyanobacteria, as photoautotrophic organisms, provide the opportunity to convert CO2 to biomass with light as the sole energy source. Like many other prokaryotes, especially under nutrient deprivation, most cyanobacteria are able to produce polyhydroxyalkanoates (PHAs) as intracellular energy and carbon storage compounds. In contrast to heterotrophic PHA producers, photoautotrophic cyanobacteria do not consume sugars and, therefore, do not depend on agricultural crops, which makes them a green alternative production system. This review summarizes the recent advances in cyanobacterial PHA production. Furthermore, this study reports the working experience with different strains and cultivating conditions in a 200 L pilot plant. The tubular photobioreactor was built at the coal power plant in Dürnrohr, Austria in 2013 for direct utilization of flue gases. The main challenges were the selection of robust production strains, process optimization, and automation, as well as the CO2 availability. PMID:28952505

Discovering new points of differentiation.

PubMed

MacMillan, I C; McGrath, R G

1997-01-01

Most profitable strategies are built on differentiation: offering customers something they value that competitors don't have. But most companies concentrate only on their products or services. In fact, a company can differentiate itself every point where it comes in contact with its customers--from the moment customers realize they need a product or service to the time when they dispose of it. The authors believe that if companies open up their thinking to their customer's entire experience with a product or service--the consumption chain--they can uncover opportunities to position their offerings in ways that neither they nor their competitors though possible. The authors show how even a mundane product such as candles can be successfully differentiated. By analyzing its customers' experiences and exploring various options, Blyth Industries, for example, has grown from a $2 million U.S. candle manufacturer into a global candle and accessory business with nearly $500 million in sales and a market value of $1.2 billion. Finding ways to differentiate one's company is a skill that can be nurtured, the authors contend. In this Manager's Tool Kit, they have designed a two-part approach that can help companies continually identify new points of differentiation and develop the ability to generate successful differentiation strategies. "Mapping the Consumption Chain" captures the customer's total experience with a product or service. "Analyzing Your Customer's Experience" shows managers how directed brainstorming about each step in the consumption chain can elicit numerous ways to differentiate any offering.

Fuzzy Books and Sideways Looks: Discourses of Schooling on Australian Television Advertisements

ERIC Educational Resources Information Center

Drew, Christopher

2015-01-01

Media constructions of schooling provide suggestions about what should be expected of the school experience. Studies on discourses of schooling have examined how the school is framed in media discourses, but few have examined how it is formed mundanely and repeatedly in advertisements promoting products that are not directly educational. This…

Soil carbon changes: comparing flux monitoring and mass balance in a box lysimeter experiment.

Treesearch

S.M. Nay; B.T. Bormann

2000-01-01

Direct measures of soil-surface respiration are needed to evaluate belowground biological processes, forest productivity, and ecosystem responses to global change. Although infra-red gas analyzer {IRGA) methods track reference CO2 flows in lab studies, questions remain for extrapolating IRGA methods to field conditions. We constructed 10 box...

The influence of drought-heat stress on long term carbon fluxes of bioenergy crops grown in the Midwestern US

USDA-ARS?s Scientific Manuscript database

Perennial grasses are promising feedstocks for bioenergy production in the Midwestern US. Few experiments have addressed how drought influences their carbon fluxes and storage. This study provides a direct comparison of ecosystem-scale measurements of carbon fluxes associated with miscanthus (Miscan...

A Theory for the Neural Basis of Language Part 2: Simulation Studies of the Model

ERIC Educational Resources Information Center

Baron, R. J.

1974-01-01

Computer simulation studies of the proposed model are presented. Processes demonstrated are (1) verbally directed recall of visual experience; (2) understanding of verbal information; (3) aspects of learning and forgetting; (4) the dependence of recognition and understanding in context; and (5) elementary concepts of sentence production. (Author)

Biomass consumption during prescribed fires in big sagebrush ecosystems

Treesearch

Clinton S. Wright; Susan J. Prichard

2006-01-01

Big sagebrush (Artemisia tridentata) ecosystems typically experience stand replacing fires during which some or all of the ignited biomass is consumed. Biomass consumption is directly related to the energy released during a fire, and is an important factor that determines smoke production and the effects of fire on other resources. Consumption of...

[Recent developments on the European ban on animal experiments for cosmetics].

PubMed

Ruhdel, I W

2001-01-01

For the second time the European Commission has postponed the sales ban on cosmetics products that have been developed and tested in animal experiments now until 2002. In the meantime the Commission wants to adopt the Seventh Amendment of the EU Cosmetics Directive. In its draft the Commission proposes to scrap the sales ban and replace it with an animal testing ban. This change would avoid possible conflicts with the WTO, however, from the animal welfare point of view would result in animal testing moving into third countries instead of avoiding them. This is because cosmetics products tested on animals outside the EU could be sold in the EU without any restrictions. As a consequence this measure would take the pressure from authorities and industry to further develop and adopt alternative methods. Other proposed measures are not acceptable from the animal welfare point of view, e.g. because they contradict Directive 86/609 and would result in a delay of the application of validated alternative methods. The Deutscher Tierschutzbund therefore still demands an immediate and complete sales ban in connection with an animal testing ban within the EU.

Consumer-directed health plans: enrollee views, early employer experience.

PubMed

Frates, Janice; Severoni, Ellen

2005-06-01

Consumer-directed health plans (CDHPs) are a new health insurance product that is of growing interest to employers who are struggling to cope with rising health insurance premium costs and to consumers who are desiring more choice and engagement in their health care. This paper presents the results of a study of California consumer awareness of, and attitudes toward, CDHPs in the context of several national surveys and the experiences of some early-adopting employers. California Health Decisions conducted a telephone survey of 800 insured adult California residents in November 2002. Few respondents had heard of CDHPs. They appealed more to younger, single, less educated, and healthier respondents and those who did not understand them well. The most attractive CDHP features were greater provider choice and health savings accounts' portability and flexibility. Concerns centered on personal financial exposure. While CDHPs' commercial market penetration is increasing, their greatest potential future contributions might be to reduce the number of uninsured Americans by offering an affordable health insurance product and to fund additional health services for retirees. As CDHPs further evolve, more consumer involvement in their refinement, implementation, and evaluation is essential.

Biotic and abiotic degradation of 1,1,2,2-tetrachloroethane in wetland sediments: Geochemical and microbial community analyses

USGS Publications Warehouse

Lorah, M.M.; Voytek, M.A.; Kirshtein, J.

2000-01-01

Additional microcosm experiments with the wetland sediment and groundwater at the Aberdeen Proving Ground, MD, site was presented to assist in elucidating the conditions under which these potentially competing biotic and abiotic degradation reactions for 1,1,2,2-tetrachloroethane (PCA) occur in the environment and to evaluate potential seasonal changes in degradation reactions. PCA concentration decreased to below detection within 21 days in the March 1999 experiment, while PCA was still present at day 35 in the July 1999 experiment. Compared to March 1999 experiment, peak concentrations of all daughter products except trichloroethylene (TCE) were delayed in the July 1999 experiment. The relative intensity of the peaks was directly related to the biomass present for each fragment length (bp, base pair). The relative intensities were lower in sediment collected in August 1999 than in March 1999, especially in the bp size range of ??? 160??-240??. These microbial community analyses, along with the geochemical analyses of the microcosms, provide evidence that abiotic production of TCE from PCA degradation is more significant under conditions of low bacterial biomass in the wetland sediments.

Electrophysiological Evidence for Use of the Animacy Hierarchy, but not Thematic Role Assignment, During Verb Argument Processing

PubMed Central

Paczynski, Martin; Kuperberg, Gina R.

2011-01-01

Animacy is known to play an important role in language processing and production, but debate remains as to how it exerts its effects: 1) through links to syntactic ordering, 2) through inherent differences between animate and inanimate entities in their salience/lexico-semantic accessibility, 3) through links to specific thematic roles. We contrasted these three accounts in two event related potential (ERP) experiments examining the processing of direct object arguments in simple English sentences. In Experiment 1, we found a larger N400 to animate than inanimate direct object arguments assigned the Patient role, ruling out the second account. In Experiment 2 we found no difference in the N400 evoked by animate direct object arguments assigned the Patient role (prototypically inanimate) and those assigned the Experiencer role (prototypically animate), ruling out the third account. We therefore suggest that animacy may impact processing through a direct link to syntactic linear ordering, at least on post-verbal arguments in English. We also examined processing on direct object arguments that violated the animacy-based selection restriction constraints of their preceding verbs. These violations evoked a robust P600, which was not modulated by thematic role assignment or reversibility, suggesting that the so-called semantic P600 is driven by overall propositional impossibility, rather than thematic role reanalysis. PMID:22199415

Nutrient enrichment, biodiversity loss, and consequent declines in ecosystem productivity.

PubMed

Isbell, Forest; Reich, Peter B; Tilman, David; Hobbie, Sarah E; Polasky, Stephen; Binder, Seth

2013-07-16

Anthropogenic drivers of environmental change often have multiple effects, including changes in biodiversity, species composition, and ecosystem functioning. It remains unknown whether such shifts in biodiversity and species composition may, themselves, be major contributors to the total, long-term impacts of anthropogenic drivers on ecosystem functioning. Moreover, although numerous experiments have shown that random losses of species impact the functioning of ecosystems, human-caused losses of biodiversity are rarely random. Here we use results from long-term grassland field experiments to test for direct effects of chronic nutrient enrichment on ecosystem productivity, and for indirect effects of enrichment on productivity mediated by resultant species losses. We found that ecosystem productivity decreased through time most in plots that lost the most species. Chronic nitrogen addition also led to the nonrandom loss of initially dominant native perennial C4 grasses. This loss of dominant plant species was associated with twice as great a loss of productivity per lost species than occurred with random species loss in a nearby biodiversity experiment. Thus, although chronic nitrogen enrichment initially increased productivity, it also led to loss of plant species, including initially dominant species, which then caused substantial diminishing returns from nitrogen fertilization. In contrast, elevated CO2 did not decrease grassland plant diversity, and it consistently promoted productivity over time. Our results support the hypothesis that the long-term impacts of anthropogenic drivers of environmental change on ecosystem functioning can strongly depend on how such drivers gradually decrease biodiversity and restructure communities.

Arousal Rules: An Empirical Investigation into the Aesthetic Experience of Cross-Modal Perception with Emotional Visual Music

PubMed Central

Lee, Irene Eunyoung; Latchoumane, Charles-Francois V.; Jeong, Jaeseung

2017-01-01

Emotional visual music is a promising tool for the study of aesthetic perception in human psychology; however, the production of such stimuli and the mechanisms of auditory-visual emotion perception remain poorly understood. In Experiment 1, we suggested a literature-based, directive approach to emotional visual music design, and inspected the emotional meanings thereof using the self-rated psychometric and electroencephalographic (EEG) responses of the viewers. A two-dimensional (2D) approach to the assessment of emotion (the valence-arousal plane) with frontal alpha power asymmetry EEG (as a proposed index of valence) validated our visual music as an emotional stimulus. In Experiment 2, we used our synthetic stimuli to investigate possible underlying mechanisms of affective evaluation mechanisms in relation to audio and visual integration conditions between modalities (namely congruent, complementation, or incongruent combinations). In this experiment, we found that, when arousal information between auditory and visual modalities was contradictory [for example, active (+) on the audio channel but passive (−) on the video channel], the perceived emotion of cross-modal perception (visual music) followed the channel conveying the stronger arousal. Moreover, we found that an enhancement effect (heightened and compacted in subjects' emotional responses) in the aesthetic perception of visual music might occur when the two channels contained contradictory arousal information and positive congruency in valence and texture/control. To the best of our knowledge, this work is the first to propose a literature-based directive production of emotional visual music prototypes and the validations thereof for the study of cross-modally evoked aesthetic experiences in human subjects. PMID:28421007

Arousal Rules: An Empirical Investigation into the Aesthetic Experience of Cross-Modal Perception with Emotional Visual Music.

PubMed

Lee, Irene Eunyoung; Latchoumane, Charles-Francois V; Jeong, Jaeseung

2017-01-01

Emotional visual music is a promising tool for the study of aesthetic perception in human psychology; however, the production of such stimuli and the mechanisms of auditory-visual emotion perception remain poorly understood. In Experiment 1, we suggested a literature-based, directive approach to emotional visual music design, and inspected the emotional meanings thereof using the self-rated psychometric and electroencephalographic (EEG) responses of the viewers. A two-dimensional (2D) approach to the assessment of emotion (the valence-arousal plane) with frontal alpha power asymmetry EEG (as a proposed index of valence) validated our visual music as an emotional stimulus. In Experiment 2, we used our synthetic stimuli to investigate possible underlying mechanisms of affective evaluation mechanisms in relation to audio and visual integration conditions between modalities (namely congruent, complementation, or incongruent combinations). In this experiment, we found that, when arousal information between auditory and visual modalities was contradictory [for example, active (+) on the audio channel but passive (-) on the video channel], the perceived emotion of cross-modal perception (visual music) followed the channel conveying the stronger arousal. Moreover, we found that an enhancement effect (heightened and compacted in subjects' emotional responses) in the aesthetic perception of visual music might occur when the two channels contained contradictory arousal information and positive congruency in valence and texture/control. To the best of our knowledge, this work is the first to propose a literature-based directive production of emotional visual music prototypes and the validations thereof for the study of cross-modally evoked aesthetic experiences in human subjects.

Total OH reactivity study from VOC photochemical oxidation in the SAPHIR chamber

NASA Astrophysics Data System (ADS)

Yu, Z.; Tillmann, R.; Hohaus, T.; Fuchs, H.; Novelli, A.; Wegener, R.; Kaminski, M.; Schmitt, S. H.; Wahner, A.; Kiendler-Scharr, A.

2015-12-01

It is well known that hydroxyl radicals (OH) act as a dominant reactive species in the degradation of VOCs in the atmosphere. In recent field studies, directly measured total OH reactivity often showed poor agreement with OH reactivity calculated from VOC measurements (e.g. Nölscher et al., 2013; Lu et al., 2012a). This "missing OH reactivity" is attributed to unaccounted biogenic VOC emissions and/or oxidation products. The comparison of total OH reactivity being directly measured and calculated from single component measurements of VOCs and their oxidation products gives us a further understanding on the source of unmeasured reactive species in the atmosphere. This allows also the determination of the magnitude of the contribution of primary VOC emissions and their oxidation products to the missing OH reactivity. A series of experiments was carried out in the atmosphere simulation chamber SAPHIR in Jülich, Germany, to explore in detail the photochemical degradation of VOCs (isoprene, ß-pinene, limonene, and D6-benzene) by OH. The total OH reactivity was determined from the measurement of VOCs and their oxidation products by a Proton Transfer Reaction Time of Flight Mass Spectrometer (PTR-TOF-MS) with a GC/MS/FID system, and directly measured by a laser-induced fluorescence (LIF) at the same time. The comparison between these two total OH reactivity measurements showed an increase of missing OH reactivity in the presence of oxidation products of VOCs, indicating a strong contribution to missing OH reactivity from uncharacterized oxidation products.

Interspecific Neighbor Interactions Promote the Positive Diversity-Productivity Relationship in Experimental Grassland Communities

PubMed Central

Zhang, Yuhua; Wang, Yongfan; Yu, Shixiao

2014-01-01

Because the frequency of heterospecific interactions inevitably increases with species richness in a community, biodiversity effects must be expressed by such interactions. However, little is understood how heterospecific interactions affect ecosystem productivity because rarely are biodiversity ecosystem functioning experiments spatially explicitly manipulated. To test the effect of heterospecific interactions on productivity, direct evidence of heterospecific neighborhood interaction is needed. In this study we conducted experiments with a detailed spatial design to investigate whether and how heterospecific neighborhood interactions promote primary productivity in a grassland community. The results showed that increasing the heterospecific: conspecific contact ratio significantly increased productivity. We found there was a significant difference in the variation in plant height between monoculture and mixture communities, suggesting that height-asymmetric competition for light plays a central role in promoting productivity. Heterospecific interactions make tall plants grow taller and short plants become smaller in mixtures compared to monocultures, thereby increasing the efficiency of light interception and utilization. Overyielding in the mixture communities arises from the fact that the loss in the growth of short plants is compensated by the increased growth of tall plants. The positive correlation between species richness and primary production was strengthened by increasing the frequency of heterospecific interactions. We conclude that species richness significantly promotes primary ecosystem production through heterospecific neighborhood interactions. PMID:25350670

Interspecific neighbor interactions promote the positive diversity-productivity relationship in experimental grassland communities.

PubMed

Zhang, Yuhua; Wang, Yongfan; Yu, Shixiao

2014-01-01

Because the frequency of heterospecific interactions inevitably increases with species richness in a community, biodiversity effects must be expressed by such interactions. However, little is understood how heterospecific interactions affect ecosystem productivity because rarely are biodiversity ecosystem functioning experiments spatially explicitly manipulated. To test the effect of heterospecific interactions on productivity, direct evidence of heterospecific neighborhood interaction is needed. In this study we conducted experiments with a detailed spatial design to investigate whether and how heterospecific neighborhood interactions promote primary productivity in a grassland community. The results showed that increasing the heterospecific: conspecific contact ratio significantly increased productivity. We found there was a significant difference in the variation in plant height between monoculture and mixture communities, suggesting that height-asymmetric competition for light plays a central role in promoting productivity. Heterospecific interactions make tall plants grow taller and short plants become smaller in mixtures compared to monocultures, thereby increasing the efficiency of light interception and utilization. Overyielding in the mixture communities arises from the fact that the loss in the growth of short plants is compensated by the increased growth of tall plants. The positive correlation between species richness and primary production was strengthened by increasing the frequency of heterospecific interactions. We conclude that species richness significantly promotes primary ecosystem production through heterospecific neighborhood interactions.

Direct Nitrous Oxide Emission from the Aquacultured Pacific White Shrimp (Litopenaeus vannamei).

PubMed

Heisterkamp, Ines M; Schramm, Andreas; de Beer, Dirk; Stief, Peter

2016-07-01

The Pacific white shrimp (Litopenaeus vannamei) is widely used in aquaculture, where it is reared at high stocking densities, temperatures, and nutrient concentrations. Here we report that adult L. vannamei shrimp emit the greenhouse gas nitrous oxide (N2O) at an average rate of 4.3 nmol N2O/individual × h, which is 1 to 2 orders of magnitude higher than previously measured N2O emission rates for free-living aquatic invertebrates. Dissection, incubation, and inhibitor experiments with specimens from a shrimp farm in Germany indicated that N2O is mainly produced in the animal's gut by microbial denitrification. Microsensor measurements demonstrated that the gut interior is anoxic and nearly neutral and thus is favorable for denitrification by ingested bacteria. Dinitrogen (N2) and N2O accounted for 64% and 36%, respectively, of the nitrogen gas flux from the gut, suggesting that the gut passage is too fast for complete denitrification to be fully established. Indeed, shifting the rearing water bacterial community, a diet component of shrimp, from oxic to anoxic conditions induced N2O accumulation that outlasted the gut passage time. Shrimp-associated N2O production was estimated to account for 6.5% of total N2O production in the shrimp farm studied here and to contribute to the very high N2O supersaturation measured in the rearing tanks (2,099%). Microbial N2O production directly associated with aquacultured animals should be implemented into life cycle assessments of seafood production. The most widely used shrimp species in global aquaculture, Litopenaeus vannamei, is shown to emit the potent greenhouse gas nitrous oxide (N2O) at a particularly high rate. Detailed experiments reveal that N2O is produced in the oxygen-depleted gut of the animal by bacteria that are part of the shrimp diet. Upon ingestion, these bacteria experience a shift from oxic to anoxic conditions and therefore switch their metabolism to the anaerobic denitrification process, which produces N2O as an intermediate and dinitrogen (N2) gas as an end product. The N2O/N2 production ratio is unusually high in the shrimp gut, because denitrification cannot be fully established during the short gut passage time of food-associated bacteria. Nitrous oxide emission directly mediated by L. vannamei contributes significantly to the overall N2O emission from aquaculture facilities. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Direct Nitrous Oxide Emission from the Aquacultured Pacific White Shrimp (Litopenaeus vannamei)

PubMed Central

Heisterkamp, Ines M.; Schramm, Andreas; de Beer, Dirk

2016-01-01

ABSTRACT The Pacific white shrimp (Litopenaeus vannamei) is widely used in aquaculture, where it is reared at high stocking densities, temperatures, and nutrient concentrations. Here we report that adult L. vannamei shrimp emit the greenhouse gas nitrous oxide (N2O) at an average rate of 4.3 nmol N2O/individual × h, which is 1 to 2 orders of magnitude higher than previously measured N2O emission rates for free-living aquatic invertebrates. Dissection, incubation, and inhibitor experiments with specimens from a shrimp farm in Germany indicated that N2O is mainly produced in the animal's gut by microbial denitrification. Microsensor measurements demonstrated that the gut interior is anoxic and nearly neutral and thus is favorable for denitrification by ingested bacteria. Dinitrogen (N2) and N2O accounted for 64% and 36%, respectively, of the nitrogen gas flux from the gut, suggesting that the gut passage is too fast for complete denitrification to be fully established. Indeed, shifting the rearing water bacterial community, a diet component of shrimp, from oxic to anoxic conditions induced N2O accumulation that outlasted the gut passage time. Shrimp-associated N2O production was estimated to account for 6.5% of total N2O production in the shrimp farm studied here and to contribute to the very high N2O supersaturation measured in the rearing tanks (2,099%). Microbial N2O production directly associated with aquacultured animals should be implemented into life cycle assessments of seafood production. IMPORTANCE The most widely used shrimp species in global aquaculture, Litopenaeus vannamei, is shown to emit the potent greenhouse gas nitrous oxide (N2O) at a particularly high rate. Detailed experiments reveal that N2O is produced in the oxygen-depleted gut of the animal by bacteria that are part of the shrimp diet. Upon ingestion, these bacteria experience a shift from oxic to anoxic conditions and therefore switch their metabolism to the anaerobic denitrification process, which produces N2O as an intermediate and dinitrogen (N2) gas as an end product. The N2O/N2 production ratio is unusually high in the shrimp gut, because denitrification cannot be fully established during the short gut passage time of food-associated bacteria. Nitrous oxide emission directly mediated by L. vannamei contributes significantly to the overall N2O emission from aquaculture facilities. PMID:27129966

GLUCOCORTICOID TREATMENT—EFFECT ON ADRENAL MEDULLARY CATECHOLAMINE PRODUCTION

PubMed Central

Sharara-Chami, Rana I.; Joachim, Maria; Pacak, Karel; Majzoub, Joseph A.

2016-01-01

Glucocorticoid and epinephrine are important stress hormones secreted from the adrenal gland during critical illness. Adrenal glucocorticoid stimulates phenylethanolamine N-methyltransferase (PNMT) to convert norepinephrine to epinephrine in the adrenal medulla. Glucocorticoid is sometimes used in catecholamine-resistant septic shock in critically ill patients. By suppressing adrenal glucocorticoid production, glucocorticoid therapy might also reduce the secretion of epinephrine during stress. To investigate this, we used a mouse model subjected to glucocorticoid therapy under basal conditions (experiment 1) and during stress (experiment 2). In experiment 1, pellets containing 0% to 8% dexamethasone were implanted subcutaneously in mice for 4 weeks. In experiment 2, animals received 14 days of intraperitoneal injections of normal saline, low- or high-dose dexamethasone, followed by 2 h of restraint. We found that in experiment 1, adrenal corticosterone did not differ with dexamethasone treatment. Phenylethanolamine N-methyltransferase messenger RNA levels and adrenal catecholamines were highest in the 8% dexamethasone group. Compared with experiment 1, restrained control mice in experiment 2 had high adrenal corticosterone, which decreased with dexamethasone. Phenylethanolamine N-methyltransferase messenger RNA content doubled with restraint but decreased with dexamethasone treatment. As in experiment 1, adrenal catecholamine content increased significantly with dexamethasone treatment. We conclude that without stress, when adrenocorticotropic hormone is low, high doses of exogenous dexamethasone stimulate PNMT and catecholamine synthesis, likely independently of adrenal corticosterone concentration. After stress, adrenocorticotropic hormone levels are elevated, and exogenous dexamethasone suppresses endogenous corticosterone and PNMT production. Nonetheless, catecholamines increase, possibly due to direct neural stimulation, which may override the hormonal regulation of epinephrine synthesis during stress. PMID:19503019

Feeding wet distillers grains plus solubles with and without a direct-fed microbial to determine performance, carcass characteristics, and fecal shedding of O157:H7 in feedlot heifers.

PubMed

Wilson, B K; Holland, B P; Step, D L; Jacob, M E; VanOverbeke, D L; Richards, C J; Nagaraja, T G; Krehbiel, C R

2016-01-01

The inclusion of wet distillers grains plus solubles (WDGS) in feedlot diets has become a common practice in many regions of the United States due to the expanded production of byproducts and fluctuating corn prices related to ethanol production and other factors. In addition, societal concerns over the continued use of antimicrobials in agriculture production combined with an enhanced interest in disease and pathogen prevention in the food supply have led to an increased interest in use of direct-fed microbials (DFM) in growing and finishing cattle. Direct-fed microbials have been shown to improve ADG and feed efficiency, alter ruminal fermentation, and decrease fecal shedding of potential harmful pathogens in feedlot cattle in some experiments. The objective of this experiment was to evaluate the effects of WDGS inclusion with or without a DFM containing (1 × 10 cfu ∙ heifer ∙ d) combined with (1 × 10 cfu ∙ heifer ∙ d) on the performance, carcass characteristics, and O157:H7 shedding in feedlot heifers. In early August, 288 crossbred heifers (initial BW = 295 ± 28 kg) were assigned to 1 of 4 treatments (12 pens per treatment; 6 heifers per pen) in a randomized complete block design with a 2 × 2 factorial arrangement of treatments. Body weights and fecal grab samples were obtained at approximately 28-d intervals throughout the experiment. Across the feeding period, heifers fed 30% WDGS tended ( = 0.09) to have greater ADG and had greater carcass-adjusted ADG ( = 0.05) compared with heifers fed dry-rolled corn (DRC). Dry matter intake was not affected ( = 0.65) by diet, although carcass-adjusted G:F tended ( = 0.10) to be improved for heifers fed WDGS. Heifers fed 30% WDGS tended ( ≤ 0.10) to have greater fat thickness at the 12th rib, lower marbling scores, and higher yield grades. The inclusion of . combined with . in the diet had no effect ( > 0.10) on performance or carcass merit in the present experiment. The incidence of O157:H7 throughout the experiment was low, with only 18 positive samples across all sampling periods. Neither WDGS inclusion nor the inclusion of . combined with . in the diet had any effect ( > 0.10) on O157:H7 shedding in this experiment. Feeding 30% WDGS to feedlot heifers improved animal performance compared to the DRC-based control diet.

Diode pumped solid state lasers

NASA Astrophysics Data System (ADS)

Gluch, Richard P., Jr.

1990-05-01

I've come here today to share with you the experiences of an emerging company that has its hands around an emerging technology, and an interesting approach. And I'd like to make a few conmients today from a business aspect about the iaarketplace as they relate to our formulation of our market or business strategy. I'll share with you the direction on what the business strategy is and then trace with you some of the technical developments that are occurring at Laser Diode Products in St. Louis as they all relate directly to a customer requirernent.

Reaction Mechanism of Oxygen Atoms with Unsaturated Hydrocarbons by the Crossed-Molecular-Beams Method

DOE R&D Accomplishments Database

Buss, R. J.; Baseman, R. J.; Guozhong, H.; Lee, Y. T.

1982-04-01

From a series of studies of the reaction of oxygen atoms with unsaturated hydrocarbons using the crossed molecular beam method, the dominant reaction mechanisms were found to be the simple substitution reactions with oxygen atoms replacing H, Cl, Br atom or alkyl groups. Complication due to secondary reaction was avoided by carrying out experiments under single collisions and observing primary products directly. Primary products were identified by measuring the angular and velocity distributions of products at all the mass numbers which could be detected by the mass spectrometer, and from comparison of these distributions, applying the requirement of energy and momentum conservation.

Responses of soybeans and wheat to elevated CO2 in free-air and open top chamber systems

USDA-ARS?s Scientific Manuscript database

With increasing demand for agricultural products, more confidence is needed concerning impacts of rising atmospheric CO2 on crop yields. Despite debate about the merits of free-air CO2 enrichment (FACE) and open top chamber (OTC) systems, there has been only one reported experiment directly compari...

Improving Decision Making in Schools through Teacher Participation

ERIC Educational Resources Information Center

Mualuko, Ndiku J.; Mukasa, Simiyu A.; Achoka, Judy S. K.

2009-01-01

The hierarchical structure that places head teachers at the apex of a pyramid of staff is a common feature in secondary schools in Kenya. In this arrangement, school heads are poised to use their superior knowledge and experience to direct and control the working of the entire school. This negatively affects efficiency and productivity of the…

Direct electrochemical oxidation of ammonia on graphite as a treatment option for stored source-separated urine.

PubMed

Zöllig, Hanspeter; Fritzsche, Cristina; Morgenroth, Eberhard; Udert, Kai M

2015-02-01

Electrolysis can be a viable technology for ammonia removal from source-separated urine. Compared to biological nitrogen removal, electrolysis is more robust and is highly amenable to automation, which makes it especially attractive for on-site reactors. In electrolytic wastewater treatment, ammonia is usually removed by indirect oxidation through active chlorine which is produced in-situ at elevated anode potentials. However, the evolution of chlorine can lead to the formation of chlorate, perchlorate, chlorinated organic by-products and chloramines that are toxic. This study focuses on using direct ammonia oxidation on graphite at low anode potentials in order to overcome the formation of toxic by-products. With the aid of cyclic voltammetry, we demonstrated that graphite is active for direct ammonia oxidation without concomitant chlorine formation if the anode potential is between 1.1 and 1.6 V vs. SHE (standard hydrogen electrode). A comparison of potentiostatic bulk electrolysis experiments in synthetic stored urine with and without chloride confirmed that ammonia was removed exclusively by continuous direct oxidation. Direct oxidation required high pH values (pH > 9) because free ammonia was the actual reactant. In real stored urine (pH = 9.0), an ammonia removal rate of 2.9 ± 0.3 gN·m(-2)·d(-1) was achieved and the specific energy demand was 42 Wh·gN(-1) at an anode potential of 1.31 V vs. SHE. The measurements of chlorate and perchlorate as well as selected chlorinated organic by-products confirmed that no chlorinated by-products were formed in real urine. Electrode corrosion through graphite exfoliation was prevented and the surface was not poisoned by intermediate oxidation products. We conclude that direct ammonia oxidation on graphite electrodes is a treatment option for source-separated urine with three major advantages: The formation of chlorinated by-products is prevented, less energy is consumed than in indirect ammonia oxidation and readily available and cheap graphite can be used as the electrode material. Copyright © 2014 Elsevier Ltd. All rights reserved.

Protein delivery of a Ni catalyst to photosystem I for light-driven hydrogen production.

PubMed

Silver, Sunshine C; Niklas, Jens; Du, Pingwu; Poluektov, Oleg G; Tiede, David M; Utschig, Lisa M

2013-09-11

The direct conversion of sunlight into fuel is a promising means for the production of storable renewable energy. Herein, we use Nature's specialized photosynthetic machinery found in the Photosystem I (PSI) protein to drive solar fuel production from a nickel diphosphine molecular catalyst. Upon exposure to visible light, a self-assembled PSI-[Ni(P2(Ph)N2(Ph))2](BF4)2 hybrid generates H2 at a rate 2 orders of magnitude greater than rates reported for photosensitizer/[Ni(P2(Ph)N2(Ph))2](BF4)2 systems. The protein environment enables photocatalysis at pH 6.3 in completely aqueous conditions. In addition, we have developed a strategy for incorporating the Ni molecular catalyst with the native acceptor protein of PSI, flavodoxin. Photocatalysis experiments with this modified flavodoxin demonstrate a new mechanism for biohybrid creation that involves protein-directed delivery of a molecular catalyst to the reducing side of Photosystem I for light-driven catalysis. This work further establishes strategies for constructing functional, inexpensive, earth-abundant solar fuel-producing PSI hybrids that use light to rapidly produce hydrogen directly from water.

Fabrication and performance analysis of 4-sq cm indium tin oxide/InP photovoltaic solar cells

NASA Technical Reports Server (NTRS)

Gessert, T. A.; Li, X.; Phelps, P. W.; Coutts, T. J.; Tzafaras, N.

1991-01-01

Large-area photovoltaic solar cells based on direct current magnetron sputter deposition of indium tin oxide (ITO) into single-crystal p-InP substrates demonstrated both the radiation hardness and high performance necessary for extraterrestrial applications. A small-scale production project was initiated in which approximately 50 ITO/InP cells are being produced. The procedures used in this small-scale production of 4-sq cm ITO/InP cells are presented and discussed. The discussion includes analyses of performance range of all available production cells, and device performance data of the best cells thus far produced. Additionally, processing experience gained from the production of these cells is discussed, indicating other issues that may be encountered when large-scale productions are begun.

Cash transfer programme, productive activities and labour supply: Evidence from randomized experiment in Kenya

PubMed Central

Asfaw, Solomon; Davis, Benjamin; Dewbre, Josh; Handa, Sudhanshu; Winters, Paul

2015-01-01

This paper reports analysis of the impact of Kenya’s Cash Transfer for Orphans and Vulnerable Children Programme on the household decisions on productive activities using data from a randomized experimental design. Results show that the programme had a positive and significant impact on food consumption coming from home production, accumulation of productive assets, especially on the ownership of small livestock and on formation of nonfarm enterprise, especially for females. The programme has provided more flexibility to families in terms of labour allocation decisions, particularly for those who are geographically isolated. The programme was also found to have reduced child labour, an important objective of the programme. However we find very little impact of the programme on direct indicators of crop production. PMID:25663712

Template-directed synthesis on the pentanucleotide CpCpGpCpC

NASA Technical Reports Server (NTRS)

Inoue, T.; Joyce, G. F.; Grzeskowiak, K.; Orgel, L. E.; Brown, J. M.; Reese, C. B.

1984-01-01

Experiments in which CpCpGpCpC is used as a template to facilitate the co-oligomerization of 2-MeImpG and 2-MeImpC are described. It is shown that 3' to 5' prime-linked pGpGpCpGpG, whose sequence is complementary to that of the template, is substantially the most adundant pentameric product of the template-directed reaction. The yield of pGpGpCpGpG is never large (less than 20 percent), presumably becauase off-template reactions consume template-directed products. Thus pGpGpCpGpG is converted to the various isomers of G5C and G4C2 by off-template terminal addition of G or C. The 3' to 5' isomer of GpG is elongated on the template to give GpGpC, GpGpCpG, and GpGpCpGpG, while the 2' to 5' isomer does not initiate the synthesis of detectable amounts of longer oligomers.

Interrogating marine virus-host interactions and elemental transfer with BONCAT and nanoSIMS-based methods.

PubMed

Pasulka, Alexis L; Thamatrakoln, Kimberlee; Kopf, Sebastian H; Guan, Yunbin; Poulos, Bonnie; Moradian, Annie; Sweredoski, Michael J; Hess, Sonja; Sullivan, Mathew B; Bidle, Kay D; Orphan, Victoria J

2018-02-01

While the collective impact of marine viruses has become more apparent over the last decade, a deeper understanding of virus-host dynamics and the role of viruses in nutrient cycling would benefit from direct observations at the single-virus level. We describe two new complementary approaches - stable isotope probing coupled with nanoscale secondary ion mass spectrometry (nanoSIMS) and fluorescence-based biorthogonal non-canonical amino acid tagging (BONCAT) - for studying the activity and biogeochemical influence of marine viruses. These tools were developed and tested using several ecologically relevant model systems (Emiliania huxleyi/EhV207, Synechococcus sp. WH8101/Syn1 and Escherichia coli/T7). By resolving carbon and nitrogen enrichment in viral particles, we demonstrate the power of nanoSIMS tracer experiments in obtaining quantitative estimates for the total number of viruses produced directly from a particular production pathway (by isotopically labelling host substrates). Additionally, we show through laboratory experiments and a pilot field study that BONCAT can be used to directly quantify viral production (via epifluorescence microscopy) with minor sample manipulation and no dependency on conversion factors. This technique can also be used to detect newly synthesized viral proteins. Together these tools will help fill critical gaps in our understanding of the biogeochemical impact of viruses in the ocean. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

Planar Laser-Plasma Interaction Experiments at Direct-Drive Ignition-Relevant Scale Lengths at the National Ignition Facility

NASA Astrophysics Data System (ADS)

Rosenberg, M. J.; Solodov, A. A.; Seka, W.; Myatt, J. F.; Regan, S. P.; Hohenberger, M.; Epstein, R.; Froula, D. H.; Radha, P. B.; Michel, P. A.; Moody, J. D.; Masse, L.; Goyon, C.; Turnbull, D. P.; Barrios, M. A.; Bates, J. W.; Schmitt, A. J.

2016-10-01

The first experiments at the National Ignition Facility to probe laser-plasma interactions and the hot electron production at scale lengths relevant to direct-drive ignition are reported. The irradiation on one side of planar CH foils generated a plasma at the quarter-critical surface with predicted density scale lengths of Ln 600 μm, measured electron temperatures of Te 3.5 to 4.0 keV, and overlapped laser intensities of I 6 to 15 ×1014W/cm2. Optical emission from stimulated Raman scattering (SRS) and at ω/2 are correlated with the time-dependent hard x-ray signal. The fraction of laser energy converted to hot electrons increased from 0.5 % to 2.3 % as the laser intensity increased from 6 to 15 ×1014W/cm2, while the hot electron temperature was nearly constant around 40 to 50 keV. Only a sharp red-shifted feature is observed around ω/2, and both refracted and sidescattered SRS are detected, suggesting that multibeam SRS contributes to, and may even dominate, hot-electron production. These results imply a diminished presence of two-plasmon decay relative to SRS at these conditions, which has implications for hot-electron preheat mitigation strategies for direct-drive ignition. This work is supported by the DOE NNSA under Award Number DE-NA0001944.

Two Bacterial Diterpene Synthases from Allokutzneria albata for Bonnadiene and for Phomopsene and Allokutznerene.

PubMed

Lauterbach, Lukas; Rinkel, Jan; Dickschat, Jeroen Sidney

2018-05-14

Two diterpene synthases from Allokutzneria albata were studied for their products, resulting in the identification of the new compound bonnadiene from the first enzyme. Although phylogenetically unrelated to fungal phomopsene synthase, the second enzyme produced a mixture of phomopsene and a biosynthetically linked new compound, allokutznerene, besides spiroviolene. Both enzymes were deeply studied for their mechanisms by isotopic labelling experiments, metal cofactor variation and site-directed mutagenesis. Oxidation products of phomopsene and allokutznerene are also discussed. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Sterile neutrino dark matter production

NASA Astrophysics Data System (ADS)

Gorbunov, Dmitry

2017-10-01

Sterile neutrinos provide active neutrinos with masses and mixing, and hence is one of the well-motivated candidate for dark matter. We discuss the sterile neutrino production mechanisms operating in the early Universe and show that additional scalar coupled to sterile neutrino can significantly change the situation, making moderate sterile-neutrino mixing and small sterile neutrino masses consistent with current cosmological and astrophysical bounds. Further searches for a narrow line in galactic X-rays and even direct searches for keV-scale sterile neutrinos in particle physics experiments can probe the suggested setup.

Real-Time Tropospheric Product Establishment and Accuracy Assessment in China

NASA Astrophysics Data System (ADS)

Chen, M.; Guo, J.; Wu, J.; Song, W.; Zhang, D.

2018-04-01

Tropospheric delay has always been an important issue in Global Navigation Satellite System (GNSS) processing. Empirical tropospheric delay models are difficult to simulate complex and volatile atmospheric environments, resulting in poor accuracy of the empirical model and difficulty in meeting precise positioning demand. In recent years, some scholars proposed to establish real-time tropospheric product by using real-time or near-real-time GNSS observations in a small region, and achieved some good results. This paper uses real-time observing data of 210 Chinese national GNSS reference stations to estimate the tropospheric delay, and establishes ZWD grid model in the country wide. In order to analyze the influence of tropospheric grid product on wide-area real-time PPP, this paper compares the method of taking ZWD grid product as a constraint with the model correction method. The results show that the ZWD grid product estimated based on the national reference stations can improve PPP accuracy and convergence speed. The accuracy in the north (N), east (E) and up (U) direction increase by 31.8 %,15.6 % and 38.3 %, respectively. As with the convergence speed, the accuracy of U direction experiences the most improvement.

Direct detection of light dark matter and solar neutrinos via color center production in crystals

NASA Astrophysics Data System (ADS)

Budnik, Ranny; Cheshnovsky, Ori; Slone, Oren; Volansky, Tomer

2018-07-01

We propose a new low-threshold direct-detection concept for dark matter and for coherent nuclear scattering of solar neutrinos, based on the dissociation of atoms and subsequent creation of color center type defects within a lattice. The novelty in our approach lies in its ability to detect single defects in a macroscopic bulk of material. This class of experiments features ultra-low energy thresholds which allows for the probing of dark matter as light as O (10) MeV through nuclear scattering. Another feature of defect creation in crystals is directional information, which presents as a spectacular signal and a handle on background reduction in the form of daily modulation of the interaction rate. We discuss the envisioned setup and detection technique, as well as background reduction. We further calculate the expected rates for dark matter and solar neutrinos in two example crystals for which available data exists, demonstrating the prospective sensitivity of such experiments.

Field_ac: a research project on ocean modelling in coastal areas. The experience in the Catalan Sea.

NASA Astrophysics Data System (ADS)

Grifoll, Manel; Pallarès, Elena; Tolosana-Delgado, Raimon; Fernandez, Juan; Lopez, Jaime; Mosso, Cesar; Hermosilla, Fernando; Espino, Manuel; Sanchez-Arcilla, Agustín

2013-04-01

The EU founded Field_ac project has investigated during the last three years methods and strategies for improving operational services in coastal areas. The objective has been to generate added value for shelf and regional scale predictions from GMES Marine Core Services. In this sense the experience in the Catalan Sea site has allowed to combine high-resolution numerical modeling tools nested into regional GMES services, data from intensive field campaigns or local observational networks and remote sensing products. Multi-scale coupled models have been implemented to evaluate different temporal and spatial scales of the dominant physical processes related with waves, currents, continental/river discharges or sediment transport. In this sense the experience of the Field_ac project in the Catalan Sea has permit to "connect" GMES marine core service results to the coastal (local) anthropogenic forcing (e.g. causes of morphodynamic evolution and ecosystem degradation) and will support a knowledge-based assessment of decisions in the coastal zone. This will contribute to the implementation of EU directives (e.g., the Water Framework Directive for water quality at beaches near harbour entrances or the Risk or Flood Directives for waves and sea-level at beach/river-mouth scales).

Predictive Finite Rate Model for Oxygen-Carbon Interactions at High Temperature

NASA Astrophysics Data System (ADS)

Poovathingal, Savio

An oxidation model for carbon surfaces is developed to predict ablation rates for carbon heat shields used in hypersonic vehicles. Unlike existing empirical models, the approach used here was to probe gas-surface interactions individually and then based on an understanding of the relevant fundamental processes, build a predictive model that would be accurate over a wide range of pressures and temperatures, and even microstructures. Initially, molecular dynamics was used to understand the oxidation processes on the surface. The molecular dynamics simulations were compared to molecular beam experiments and good qualitative agreement was observed. The simulations reproduced cylindrical pitting observed in the experiments where oxidation was rapid and primarily occurred around a defect. However, the studies were limited to small systems at low temperatures and could simulate time scales only of the order of nanoseconds. Molecular beam experiments at high surface temperature indicated that a majority of surface reaction products were produced through thermal mechanisms. Since the reactions were thermal, they occurred over long time scales which were computationally prohibitive for molecular dynamics to simulate. The experiments provided detailed dynamical data on the scattering of O, O2, CO, and CO2 and it was found that the data from molecular beam experiments could be used directly to build a model. The data was initially used to deduce surface reaction probabilities at 800 K. The reaction probabilities were then incorporated into the direct simulation Monte Carlo (DSMC) method. Simulations were performed where the microstructure was resolved and dissociated oxygen convected and diffused towards it. For a gas-surface temperature of 800 K, it was found that despite CO being the dominant surface reaction product, a gas-phase reaction forms significant CO2 within the microstructure region. It was also found that surface area did not play any role in concentration of reaction products because the reaction probabilities were in the diffusion dominant regime. The molecular beam data at different surface temperatures was then used to build a finite rate model. Each reaction mechanism and all rate parameters of the new model were determined individually based on the molecular beam data. Despite the experiments being performed at near vacuum conditions, the finite rate model developed using the data could be used at pressures and temperatures relevant to hypersonic conditions. The new model was implemented in a computational fluid dynamics (CFD) solver and flow over a hypersonic vehicle was simulated. The new model predicted similar overall mass loss rates compared to existing models, however, the individual species production rates were completely different. The most notable difference was that the new model (based on molecular beam data) predicts CO as the oxidation reaction product with virtually no CO2 production, whereas existing models predict the exact opposite trend. CO being the dominant oxidation product is consistent with recent high enthalpy wind tunnel experiments. The discovery that measurements taken in molecular beam facilities are able to determine individual reaction mechanisms, including dependence on surface coverage, opens up an entirely new way of constructing ablation models.

Consumer-directed health plans: mixed employer signals, complex market dynamics.

PubMed

Tynan, Ann; Christianson, Jon B

2008-03-01

Health plans have expanded consumer-directed health plan (CDHP) product offerings--typically high-deductible health plans coupled with a spending account--and more employers are offering these products to workers, according to findings from the Center for Studying Health System Change's (HSC) 2007 site visits to 12 nationally representative metropolitan communities. In developing CDHPs, health plans are responding to a broader employer strategy to confer more responsibility on workers for their health care costs, lifestyle choices and treatment decisions. CDHP adoption by employers and consumers depends on a range of factors, including product features and employer characteristics, and varies across the 12 communities. While more large employers are introducing CDHPs into health benefit programs, adoption of CDHPs remains modest. Health plans and employers expect CDHP enrollment to grow as employers and employees become more knowledgeable about CDHP features, health plans develop more sophisticated support tools for plan enrollees, and there are more opportunities to learn from early adopters' experiences.early

Determinants of structural choice in visually situated sentence production.

PubMed

Myachykov, Andriy; Garrod, Simon; Scheepers, Christoph

2012-11-01

Three experiments investigated how perceptual, structural, and lexical cues affect structural choices during English transitive sentence production. Participants described transitive events under combinations of visual cueing of attention (toward either agent or patient) and structural priming with and without semantic match between the notional verb in the prime and the target event. Speakers had a stronger preference for passive-voice sentences (1) when their attention was directed to the patient, (2) upon reading a passive-voice prime, and (3) when the verb in the prime matched the target event. The verb-match effect was the by-product of an interaction between visual cueing and verb match: the increase in the proportion of passive-voice responses with matching verbs was limited to the agent-cued condition. Persistence of visual cueing effects in the presence of both structural and lexical cues suggests a strong coupling between referent-directed visual attention and Subject assignment in a spoken sentence. Copyright © 2012 Elsevier B.V. All rights reserved.

Pulsed direct and constant direct currents in the pilocarpine iontophoresis sweat chloride test.

PubMed

Gomez, Carla Cristina Souza; Servidoni, Maria de Fatima; Marson, Fernando Augusto de Lima; Canavezi, Paulo Jose Coelho; Vinagre, Adriana Mendes; Costa, Eduardo Tavares; Ribeiro, Antonio Fernando; Ribeiro, Maria Angela Gonçalves de Oliveira; Toro, Adyleia Aparecida Dalbo Contrera; Pavan, Celia Regina; Rondon, Michelle Vivine Sá Dos Santos; Lorena, Sonia Leticia Silva; Vieria, Francisco Ubaldi; Ribeiro, Jose Dirceu

2014-12-13

The classic sweat test (CST) is the golden standard for cystic fibrosis (CF) diagnosis. Then, our aim was compare the production and volume of sweat, and side effects caused by pulsed direct current (PDC) and constant direct current (CDC). To determine the optimal stimulation time (ST) for the sweat collection. To verify the PDC as CF diagnosis option. Prospective study with cross-sectional experimental intervention. Experiment 1 (right arm): PDC and CDC. ST at 10 min and sweat collected at 30 min. Currents of 0.5; 0.75; 1.0 and 1.5 mA and frequencies of 0, 200, 1,000 and 5,000 Hz applied. Experiment 2 (left arm): current of 1.0 mA, ST at 5 and 10 min and sweat collected at 15 and 30 min with frequencies of 0; 200; 1,000 and 5,000 Hz applied Experiments 1 and 2 were performed with current density (CD) from 0.07 to 0.21 mA/cm2. Experiment 3: PDC was used in typical CF patients with two CFTR mutations screened and or with CF diagnosis by rectal biopsy and patients with atypical CF. 48 subjects (79.16% female) with average of 29.54 ± 8.87 years old were enrolled. There was no statistical difference between the interaction of frequency and current in the sweat weight (p = 0.7488). Individually, positive association was achieved between weight sweat and stimulation frequency (p = 0.0088); and current (p = 0.0025). The sweat production was higher for 10 min of stimulation (p = 0.0023). The sweat collection was better for 30 min (p = 0.0019). The skin impedance was not influenced by ST and sweat collection (p > 0.05). The current frequency was inversely associated with the skin impedance (p < 0.0001). The skin temperature measured before stimulation was higher than after (p < 0.0001). In Experiment 3 (29 subjects) the PDC showed better kappa index compared to CDC (0.9218 versus 0.5205, respectively). The performance of the CST with CDC and PDC with CD of 0.14 to 0.21 mA/cm2 showed efficacy in steps of stimulation and collection of sweat, without side effects. The optimal stimulation time and sweat collection were, respectively, 10 and 30 min.

Vat rates on medical devices: foreign experience and Ukrainian practice.

PubMed

Pashkov, Vitalii; Hutorova, Nataliia; Harkusha, Andrii

2017-01-01

In Ukraine differentiated VAT rates is a matter of debate. Today the Cabinet approved a list of medical products that has been changed three times resulting in changed VAT rates for specific products. European Union provides another method of regulation of VAT rates on medical devices. The abovementioned demonstrates the relevance of this study. Comparative analysis of Ukrainian and European Union legislation based on dialectical, comparative, analytic, synthetic and comprehensive research methods were used in this article. In Ukraine general rate of VAT for all business activities is 20 %. But for medical devices, Tax Code of Ukraine provides special rules. VAT rate of 7% for transactions supplies into Ukraine and imported into the customs territory of Ukraine of medical products on the list approved by the Cabinet. The list generated by the medical product name and nomenclature code that does not correspond to European experience and Council Directive 2006/112/EC. In our opinion, reduced VAT rates should to be established for all medical devices that are in a stream of commerce, have all necessary documents, that proved their quality and safety and fall under definition of medical devices.

Impacts of climate change drivers on C4 grassland productivity: scaling driver effects through the plant community.

PubMed

Polley, H Wayne; Derner, Justin D; Jackson, Robert B; Wilsey, Brian J; Fay, Philip A

2014-07-01

Climate change drivers affect plant community productivity via three pathways: (i) direct effects of drivers on plants; (ii) the response of species abundances to drivers (community response); and (iii) the feedback effect of community change on productivity (community effect). The contribution of each pathway to driver-productivity relationships depends on functional traits of dominant species. We used data from three experiments in Texas, USA, to assess the role of community dynamics in the aboveground net primary productivity (ANPP) response of C4 grasslands to two climate drivers applied singly: atmospheric CO2 enrichment and augmented summer precipitation. The ANPP-driver response differed among experiments because community responses and effects differed. ANPP increased by 80-120g m(-2) per 100 μl l(-1) rise in CO2 in separate experiments with pasture and tallgrass prairie assemblages. Augmenting ambient precipitation by 128mm during one summer month each year increased ANPP more in native than in exotic communities in a third experiment. The community effect accounted for 21-38% of the ANPP CO2 response in the prairie experiment but little of the response in the pasture experiment. The community response to CO2 was linked to species traits associated with greater soil water from reduced transpiration (e.g. greater height). Community effects on the ANPP CO2 response and the greater ANPP response of native than exotic communities to augmented precipitation depended on species differences in transpiration efficiency. These results indicate that feedbacks from community change influenced ANPP-driver responses. However, the species traits that regulated community effects on ANPP differed from the traits that determined how communities responded to drivers. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Productivity and fishing pressure drive variability in fish parasite assemblages of the Line Islands, equatorial Pacific.

PubMed

Wood, Chelsea L; Baum, Julia K; Reddy, Sheila M W; Trebilco, Rowan; Sandin, Stuart A; Zgliczynski, Brian J; Briggs, Amy A; Micheli, Fiorenza

2015-05-01

Variability in primary productivity and fishing pressure can shape the abundance, species composition, and diversity of marine life. Though parasites comprise nearly half of marine species, their responses to these important forces remain little explored. We quantified parasite assemblages at two spatial scales, across a gradient in productivity and fishing pressure that spans six coral islands of the Line Islands archipelago and within the largest Line Island, Kiritimati, which experiences a west-to-east gradient in fishing pressure and upwelling-driven productivity. In the across-islands data set, we found that increasing productivity was correlated with increased parasite abundance overall, but that the effects of productivity differed among parasite groups. Trophically transmitted parasites increased in abundance with increasing productivity, but directly transmitted parasites did not exhibit significant changes. This probably arises because productivity has stronger effects on the abundance of the planktonic crustaceans and herbivorous snails that serve as the intermediate hosts of trophically transmitted parasites than on the higher-trophic level fishes that are the sole hosts of directly transmitted parasites. We also found that specialist parasites increased in response to increasing productivity, while generalists did not, possibly because specialist parasites tend to be more strongly limited by host availability than are generalist parasites. After the effect of productivity was controlled for, fishing was correlated with decreases in the abundance of trophically transmitted parasites, while directly transmitted parasites appeared to track host density; we observed increases in the abundance of parasites using hosts that experienced fishing-driven compensatory increases in abundance. The within-island data set confirmed these patterns for the combined effects of productivity and fishing on parasite abundance, suggesting that our conclusions are robust across a span of spatial scales. Overall, these results indicate that there are strong and variable effects of anthropogenic and natural drivers on parasite abundance and taxonomic richness. These effects are likely to be mediated by parasite traits, particularly by parasite transmission strategies.

Design, construction, and testing of the direct absorption receiver panel research experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chavez, J.M.; Rush, E.E.; Matthews, C.W.

1990-01-01

A panel research experiment (PRE) was designed, built, and tested as a scaled-down model of a direct absorption receiver (DAR). The PRE is a 3-MW{sub t}DAR experiment that will allow flow testing with molten nitrate salt and provide a test bed for DAR testing with actual solar heating. In a solar central receiver system DAR, the heat absorbing fluid (a blackened molten nitrate salt) flows in a thin film down a vertical panel (rather than through tubes as in conventional receiver designs) and absorbs the concentrated solar flux directly. The ability of the flowing salt film to absorb flux directly.more » The ability of the flowing salt film to absorb the incident solar flux depends on the panel design, hydraulic and thermal fluid flow characteristics, and fluid blackener properties. Testing of the PRE is being conducted to demonstrate the engineering feasibility of the DAR concept. The DAR concept is being investigated because it offers numerous potential performance and economic advantages for production of electricity when compared to other solar receiver designs. The PRE utilized a 1-m wide by 6-m long absorber panel. The salt flow tests are being used to investigate component performance, panel deformations, and fluid stability. Salt flow testing has demonstrated that all the DAR components work as designed and that there are fluid stability issues that need to be addressed. Future solar testing will include steady-state and transient experiments, thermal loss measurements, responses to severe flux and temperature gradients and determination of peak flux capability, and optimized operation. In this paper, we describe the design, construction, and some preliminary flow test results of the Panel Research Experiment. 11 refs., 8 figs., 2 tabs.« less

Chemical dynamics simulations of the monohydrated OH-(H2O) + CH3I reaction. Atomic-level mechanisms and comparison with experiment

NASA Astrophysics Data System (ADS)

Xie, Jing; Otto, Rico; Wester, Roland; Hase, William L.

2015-06-01

Direct dynamics simulations, with B97-1/ECP/d theory, were performed to study the role of microsolvation for the OH-(H2O) + CH3I reaction. The SN2 reaction dominates at all reactant collision energies, but at higher collision energies proton transfer to form CH2I-, and to a lesser extent CH2I- (H2O), becomes important. The SN2 reaction occurs by direct rebound and stripping mechanisms, and 28 different indirect atomistic mechanisms, with the latter dominating. Important components of the indirect mechanisms are the roundabout and formation of SN2 and proton transfer pre-reaction complexes and intermediates, including [CH3--I--OH]-. In contrast, for the unsolvated OH- + CH3I SN2 reaction, there are only seven indirect atomistic mechanisms and the direct mechanisms dominate. Overall, the simulation results for the OH-(H2O) + CH3IߙSN2 reaction are in good agreement with experiment with respect to reaction rate constant, product branching ratio, etc. Differences between simulation and experiment are present for the SN2 velocity scattering angle at high collision energies and the proton transfer probability at low collision energies. Equilibrium solvation by the H2O molecule is unimportant. The SN2 reaction is dominated by events in which H2O leaves the reactive system as CH3OH is formed or before CH3OH formation. Formation of solvated products is unimportant and participation of the (H2O)CH3OH---I- post-reaction complex for the SN2 reaction is negligible.

Tensile Properties Characterization of AlSi10Mg Parts Produced by Direct Metal Laser Sintering via Nested Effects Modeling.

PubMed

Palumbo, Biagio; Del Re, Francesco; Martorelli, Massimo; Lanzotti, Antonio; Corrado, Pasquale

2017-02-08

A statistical approach for the characterization of Additive Manufacturing (AM) processes is presented in this paper. Design of Experiments (DOE) and ANalysis of VAriance (ANOVA), both based on Nested Effects Modeling (NEM) technique, are adopted to assess the effect of different laser exposure strategies on physical and mechanical properties of AlSi10Mg parts produced by Direct Metal Laser Sintering (DMLS). Due to the wide industrial interest in AM technologies in many different fields, it is extremely important to ensure high parts performances and productivity. For this aim, the present paper focuses on the evaluation of tensile properties of specimens built with different laser exposure strategies. Two optimal laser parameters settings, in terms of both process quality (part performances) and productivity (part build rate), are identified.

Tensile Properties Characterization of AlSi10Mg Parts Produced by Direct Metal Laser Sintering via Nested Effects Modeling

PubMed Central

Palumbo, Biagio; Del Re, Francesco; Martorelli, Massimo; Lanzotti, Antonio; Corrado, Pasquale

2017-01-01

A statistical approach for the characterization of Additive Manufacturing (AM) processes is presented in this paper. Design of Experiments (DOE) and ANalysis of VAriance (ANOVA), both based on Nested Effects Modeling (NEM) technique, are adopted to assess the effect of different laser exposure strategies on physical and mechanical properties of AlSi10Mg parts produced by Direct Metal Laser Sintering (DMLS). Due to the wide industrial interest in AM technologies in many different fields, it is extremely important to ensure high parts performances and productivity. For this aim, the present paper focuses on the evaluation of tensile properties of specimens built with different laser exposure strategies. Two optimal laser parameters settings, in terms of both process quality (part performances) and productivity (part build rate), are identified. PMID:28772505

(125)I-Tetrazines and Inverse-Electron-Demand Diels-Alder Chemistry: A Convenient Radioiodination Strategy for Biomolecule Labeling, Screening, and Biodistribution Studies.

PubMed

Albu, Silvia A; Al-Karmi, Salma A; Vito, Alyssa; Dzandzi, James P K; Zlitni, Aimen; Beckford-Vera, Denis; Blacker, Megan; Janzen, Nancy; Patel, Ramesh M; Capretta, Alfredo; Valliant, John F

2016-01-20

A convenient method to prepare radioiodinated tetrazines was developed, such that a bioorthogonal inverse electron demand Diels-Alder reaction can be used to label biomolecules with iodine-125 for in vitro screening and in vivo biodistribution studies. The tetrazine was prepared by employing a high-yielding oxidative halo destannylation reaction that concomitantly oxidized the dihydrotetrazine precursor. The product reacts quickly and efficiently with trans-cyclooctene derivatives. Utility was demonstrated through antibody and hormone labeling experiments and by evaluating products using standard analytical methods, in vitro assays, and quantitative biodistribution studies where the latter was performed in direct comparison to Bolton-Hunter and direct iodination methods. The approach described provides a convenient and advantageous alternative to conventional protein iodination methods that can expedite preclinical development and evaluation of biotherapeutics.

76 FR 56279 - Airworthiness Directives; Airbus Model A318, A319, A320, and A321 Series Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-13

... to socket arcing at the Integrated Drive Generator (IDG) feeder cable pylon/nacelle interface connector. The fretting corrosion phenomenon was identified to be the root cause of the pin to socket arcing... products. The MCAI states: In service experience has shown a number of events of pin to socket arcing at...

Electrochemical oxidation of tramadol in low-salinity reverse osmosis concentrates using boron-doped diamond anodes.

PubMed

Lütke Eversloh, Christian; Schulz, Manoj; Wagner, Manfred; Ternes, Thomas A

2015-04-01

The electrochemical treatment of low-salinity reverse osmosis (RO) concentrates was investigated using tramadol (100 μM) as a model substance for persistent organic contaminants. Galvanostatic degradation experiments using boron-doped diamond electrodes at different applied currents were conducted in RO concentrates as well as in ultra-pure water containing either sodium chloride or sodium sulfate. Kinetic investigations revealed a significant influence of in-situ generated active chlorine besides direct anodic oxidation. Therefore, tramadol concentrations decreased more rapidly at elevated chloride content. Nevertheless, reduction of total organic carbon (TOC) was found to be comparatively low, demonstrating that transformation rather than mineralization was taking place. Early stage product formation could be attributed to both direct and indirect processes, including demethylation, hydroxylation, dehydration, oxidative aromatic ring cleavage and halogenation reactions. The latter led to various halogenated derivatives and resulted in AOX (adsorbable organic halogens) formation in the lower mg/L-range depending on the treatment conditions. Characterisation of transformation products (TPs) was achieved via MS(n) experiments and additional NMR measurements. Based on identification and quantification of the main TPs in different matrices and on additional potentiostatic electrolysis, a transformation pathway was proposed. Copyright © 2014 Elsevier Ltd. All rights reserved.

Interactive analysis and evaluation of ERTS data for regional planning and urban development: A Los Angeles Basin case study

NASA Technical Reports Server (NTRS)

Raje, S.; Economy, R.; Willoughby, G.; Mcknight, J.

1974-01-01

The progression endemic to the ERTS Data Use Experiment SR 124 in data quality, analysis sophistication and applications responsiveness is reviewed. The roles of the variety of ERTS products, including the supporting underflight aircraft imagery at various scales, are discussed in the context of this investigation. The versatility of interpretation techniques and outputs developed and implemented via the General Electric Multispectral Information Extraction Systems is described and exemplified by both system-expository and applications-explanatory products. The wide-ranging and in-depth applications studied in the course of this experiment can be characterized as community-oriented and agency-directed. In the former, generic category, which is primarily data-contextual, problems analyzed dealt with agricultural systems, surface water bodies, snow cover, brush fire burns, forestry, grass growth, parks - golf courses - cemeteries, dust storms, grading sites, geological features and coastal water structure. The ERTS MSS band selectivity and measurements thresholds were of primary interest here. The agency-directed application areas have been user-evaluational in nature. Beginning with overall urbanized regional analysis of land cover density-development intensity, residential areas were analyzed for ascertaining if housing types could be aggregated with any degree of reliability.

Developing Research Capabilities in Energy Biosciences: Design principles of photosynthetic biofuel production.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Donald D. Brown; David Savage

2012-06-30

The current fossil fuel-based energy infrastructure is not sustainable. Solar radiation is a plausible alternative, but realizing it as such will require significant technological advances in the ability to harvest light energy and convert it into suitable fuels. The biological system of photosynthesis can carry out these reactions, and in principle could be engineered using the tools of synthetic biology. One desirable implementation would be to rewire the reactions of a photosynthetic bacterium to direct the energy harvested from solar radiation into the synthesis of the biofuel H2. Proposed here is a series of experiments to lay the basic sciencemore » groundwork for such an attempt. The goal is to elucidate the transcriptional network of photosynthesis using a novel driver-reporter screen, evolve more robust hydrogenases for improved catalysis, and to test the ability of the photosynthetic machinery to directly produce H2 in vivo. The results of these experiments will have broad implications for the understanding of photosynthesis, enzyme function, and the engineering of biological systems for sustainable energy production. The ultimate impact could be a fundamental transformation of the world's energy economy.« less

Differences In Early T-Cell Signaling In Cultures Grown In a Rotating Clinostat vs. Static Controls

NASA Technical Reports Server (NTRS)

Alexamder. M.; Nelman-Gonzales, M.; Penkala, J.; Sams, C.

1999-01-01

Altered gravity has previously been demonstrated to be a stress that can influence components of the immune system. Specifically, T-cell activation has been shown to be affected by changes in gravity, exhibiting a decrease in proliferative response to in vitro stimulation in microgravity. Subsequent ground based studies utilizing a rotating clinostat to model some of the effects of microgravity have been consistent with earlier flight based experiments. These ground and flight experiments have examined T-cell activation by measuring various responses including production of cytokines, DNA synthesis and the production of various cell surface activation markers. These indicators of T-cell activation were measured anywhere from 4 to 72 hours after stimulation. Prior to the work described here, the initial signaling events in T-cell activation had not been directly examined. The goal of this project was to determine how the process of early signal transduction was affected by growth in a rotating clinostat. Here we directly show a defect in signaling from TCR to MAPK in purified peripheral T-cells activated in the clinostat by OKT3/antiCD28 coated microbeads as compared to static controls.

Natural products for chronic cough: Text mining the East Asian historical literature for future therapeutics.

PubMed

Shergis, Johannah Linda; Wu, Lei; May, Brian H; Zhang, Anthony Lin; Guo, Xinfeng; Lu, Chuanjian; Xue, Charlie Changli

2015-08-01

Chronic cough is a significant health burden. Patients experience variable benefits from over the counter and prescribed products, but there is an unmet need to provide more effective treatments. Natural products have been used to treat cough and some plant compounds such as pseudoephedrine from ephedra and codeine from opium poppy have been developed into drugs. Text mining historical literature may offer new insight for future therapeutic development. We identified natural products used in the East Asian historical literature to treat chronic cough. Evaluation of the historical literature revealed 331 natural products used to treat chronic cough. Products included plants, minerals and animal substances. These natural products were found in 75 different books published between AD 363 and 1911. Of the 331 products, the 10 most frequently and continually used products were examined, taking into consideration findings from contemporary experimental studies. The natural products identified are promising and offer new directions in therapeutic development for treating chronic cough. © The Author(s) 2015.

Pair production by high intensity picosecond laser interacting with thick solid target at XingGuangIII

NASA Astrophysics Data System (ADS)

Wu, Yuchi; Dong, Kegong; Yan, Yonghong; Zhu, Bin; Zhang, Tiankui; Chen, Jia; Yu, Minghai; Tan, Fang; Wang, Shaoyi; Han, Dan; Lu, Feng; Gu, Yuqiu

2017-06-01

An experiment for pair production by high intensity laser irradiating thick solid targets is present. The experiment used picosecond beam of the XingGuangIII laser facility, with intensities up to several 1019 W/cm2, pulse durations about 0.8 ps and laser energies around 120 J. Pairs were generated from 1 mm-thick tantalum disk targets with different diameters from 1 mm to 10 mm. Energy spectra of hot electron from targetrear surface represent a Maxwellian distribution and obey a scaling of ∼(Iλ2)0.5. Large quantity of positrons were observed at the target rear normal direction with a yield up to 2.8 × 109 e+/sr. Owing to the target rear surface sheath field, the positrons behave as a quasi-monoenergetic beam with peak energy of several MeV. Our experiment shows that the peak energy of positron beam is inversely proportional to the target diameter.

Probing soil C metabolism in response to temperature: results from experiments and modeling

NASA Astrophysics Data System (ADS)

Dijkstra, P.; Dalder, J.; Blankinship, J.; Selmants, P. C.; Schwartz, E.; Koch, G. W.; Hart, S.; Hungate, B. A.

2010-12-01

C use efficiency (CUE) is one of the least understood aspects of soil C cycling, has a very large effect on soil respiration and C sequestration, and decreases with elevated temperature. CUE is directly related to substrate partitioning over energy production and biosynthesis. The production of energy and metabolic precursors occurs in well-known processes such as glycolysis and Krebs cycle. We have developed a new stable isotope approach using position-specific 13C-labeled metabolic tracers to measure these fundamental metabolic processes in intact soil communities (1). We use this new approach, combined with models of soil metabolic flux patterns, to analyze the response of microbial energy production, biosynthesis, and CUE to temperature. The method consists of adding small but precise amounts of position-specific 13C -labeled metabolic tracers to parallel soil incubations, in this case 1-13C and 2,3-13C pyruvate and 1-13C and U-13C glucose. The measurement of CO2 released from the labeled tracers is used to calculate the C flux rates through various metabolic pathways. A simplified metabolic model consisting of 23 reactions is iteratively solved using results of the metabolic tracer experiments and information on microbial precursor demand under different temperatures. This new method enables direct study of fundamental aspects of microbial energy production, C use efficiency, and soil organic matter formation in response to temperature. (1) Dijkstra P, Blankinship JC, Selmants PC, Hart SC, Koch GW, Schwarz E and Hungate BA. Probing metabolic flux patterns of soil microbial communities using parallel position-specific tracer labeling. Soil Biology and Biochemistry (accepted)

Decarboxylation of Δ 9-tetrahydrocannabinol: Kinetics and molecular modeling

NASA Astrophysics Data System (ADS)

Perrotin-Brunel, Helene; Buijs, Wim; van Spronsen, Jaap; van Roosmalen, Maaike J. E.; Peters, Cor J.; Verpoorte, Rob; Witkamp, Geert-Jan

2011-02-01

Efficient tetrahydrocannabinol (Δ 9-THC) production from cannabis is important for its medical application and as basis for the development of production routes of other drugs from plants. This work presents one of the steps of Δ 9-THC production from cannabis plant material, the decarboxylation reaction, transforming the Δ 9-THC-acid naturally present in the plant into the psychoactive Δ 9-THC. Results of experiments showed pseudo-first order reaction kinetics, with an activation barrier of 85 kJ mol -1 and a pre-exponential factor of 3.7 × 10 8 s -1. Using molecular modeling, two options were identified for an acid catalyzed β-keto acid type mechanism for the decarboxylation of Δ 9-THC-acid. Each of these mechanisms might play a role, depending on the actual process conditions. Formic acid proved to be a good model for a catalyst of such a reaction. Also, the computational idea of catalysis by water to catalysis by an acid, put forward by Li and Brill, and Churchev and Belbruno was extended, and a new direct keto-enol route was found. A direct keto-enol mechanism catalyzed by formic acid seems to be the best explanation for the observed activation barrier and the pre-exponential factor of the decarboxylation of Δ 9-THC-acid. Evidence for this was found by performing an extraction experiment with Cannabis Flos. It revealed the presence of short chain carboxylic acids supporting this hypothesis. The presented approach is important for the development of a sustainable production of Δ 9-THC from the plant.

Learning to lead at Toyota.

PubMed

Spear, Steven J

2004-05-01

Many companies have tried to copy Toyota's famous production system--but without success. Why? Part of the reason, says the author, is that imitators fail to recognize the underlying principles of the Toyota Production System (TPS), focusing instead on specific tools and practices. This article tells the other part of the story. Building on a previous HBR article, "Decoding the DNA of the Toyota Production System," Spear explains how Toyota inculcates managers with TPS principles. He describes the training of a star recruit--a talented young American destined for a high-level position at one of Toyota's U.S. plants. Rich in detail, the story offers four basic lessons for any company wishing to train its managers to apply Toyota's system: There's no substitute for direct observation. Toyota employees are encouraged to observe failures as they occur--for example, by sitting next to a machine on the assembly line and waiting and watching for any problems. Proposed changes should always be structured as experiments. Employees embed explicit and testable assumptions in the analysis of their work. That allows them to examine the gaps between predicted and actual results. Workers and managers should experiment as frequently as possible. The company teaches employees at all levels to achieve continuous improvement through quick, simple experiments rather than through lengthy, complex ones. Managers should coach, not fix. Toyota managers act as enablers, directing employees but not telling them where to find opportunities for improvements. Rather than undergo a brief period of cursory walk-throughs, orientations, and introductions as incoming fast-track executives at most companies might, the executive in this story learned TPS the long, hard way--by practicing it, which is how Toyota trains any new employee, regardless of rank or function.

Experiment module concepts study. Volume 1: Management summary

NASA Technical Reports Server (NTRS)

1970-01-01

The minimum number of standardized (common) module concepts that will satisfy the experiment program for manned space stations at least cost is investigated. The module interfaces with other elements such as the space shuttle, ground stations, and the experiments themselves are defined. The total experiment module program resource and test requirements are also considered. The minimum number of common module concepts that will satisfy the program at least cost is found to be three, plus a propulsion slice and certain experiment-peculiar integration hardware. The experiment modules rely on the space station for operational, maintenance, and logistic support. They are compatible with both expendable and shuttle launch vehicles, and with servicing by shuttle, tug, or directly from the space station. A total experiment module program cost of approximately $2319M under the study assumptions is indicated. This total is made up of $838M for experiment module development and production, $806M for experiment equipment, and $675M for interface hardware, experiment integration, launch and flight operations, and program management and support.

Transverse momentum dependent evolution: Matching semi-inclusive deep inelastic scattering processes to Drell-Yan and W/Z boson production

NASA Astrophysics Data System (ADS)

Sun, Peng; Yuan, Feng

2013-12-01

We examine the QCD evolution for the transverse momentum dependent observables in hard processes of semi-inclusive hadron production in deep inelastic scattering and Drell-Yan lepton pair production in pp collisions, including the spin-average cross sections and Sivers single transverse spin asymmetries. We show that the evolution equations derived by a direct integral of the Collins-Soper-Sterman evolution kernel from low to high Q can describe well the transverse momentum distributions of the unpolarized cross sections in the Q2 range from 2 to 100GeV2. In addition, the matching is established between our evolution and the Collins-Soper-Sterman resummation with b* prescription and Konychev-Nodalsky parametrization of the nonperturbative form factors, which are formulated to describe the Drell-Yan lepton pair and W/Z boson production in hadronic collisions. With these results, we present the predictions for the Sivers single transverse spin asymmetries in Drell-Yan lepton pair production and W± boson production in polarized pp and π-p collisions for several proposed experiments. We emphasize that these experiments will not only provide crucial test of the sign change of the Sivers asymmetry but also provide important opportunities to study the QCD evolution effects.

Simulation of the MoEDAL experiment

NASA Astrophysics Data System (ADS)

King, Matthew; MoEDAL Collaboration

2016-04-01

The MoEDAL experiment (Monopole and Exotics Detector at the LHC) is designed to directly search for magnetic monopoles and other highly ionising stable or meta-stable particles at the LHC. The MoEDAL detector comprises an array of plastic track detectors and aluminium trapping volumes around the P8 intersection region, opposite from the LHCb detector. TimePix devices are also installed for monitoring of the experiment. As MoEDAL mostly employs passive detectors the software development focusses on particle simulation, rather than digitisation or reconstruction. Here, we present the current status of the MoEDAL simulation software. Specifically, the development of a material description of the detector and simulations of monopole production and propagation at MoEDAL.

Application of isotope labeling experiments and (13)C flux analysis to enable rational pathway engineering.

PubMed

McAtee, Allison G; Jazmin, Lara J; Young, Jamey D

2015-12-01

Isotope labeling experiments (ILEs) and (13)C flux analysis provide actionable information for metabolic engineers to identify knockout, overexpression, and/or media optimization targets. ILEs have been used in both academic and industrial labs to increase product formation, discover novel metabolic functions in previously uncharacterized organisms, and enhance the metabolic efficiency of host cell factories. This review highlights specific examples of how ILEs have been used in conjunction with enzyme or metabolic engineering to elucidate host cell metabolism and improve product titer, rate, or yield in a directed manner. We discuss recent progress and future opportunities involving the use of ILEs and (13)C flux analysis to characterize non-model host organisms and to identify and subsequently eliminate wasteful byproduct pathways or metabolic bottlenecks. Copyright © 2015 Elsevier Ltd. All rights reserved.

The application of similar image retrieval in electronic commerce.

PubMed

Hu, YuPing; Yin, Hua; Han, Dezhi; Yu, Fei

2014-01-01

Traditional online shopping platform (OSP), which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers' experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system.

The Application of Similar Image Retrieval in Electronic Commerce

PubMed Central

Hu, YuPing; Yin, Hua; Han, Dezhi; Yu, Fei

2014-01-01

Traditional online shopping platform (OSP), which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers' experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system. PMID:24883411

Mechanical and dynamic aspects of voice production as related to voice therapy and phonosurgery.

PubMed

Isshiki, N

2000-06-01

Laryngeal framework surgery can change the position and tension of the vocal folds safely without direct surgical intervention in the vocal fold proper. Some 23 years of experience with phonosurgery have proved its usefulness in treating dysphonia related to unilateral vocal fold paralysis, vocal fold atrophy, and pitch-related dysphonias. Meanwhile, much information about the mechanism of voice production has been obtained through intraoperative findings of voice and fiberscopic examination of the larynx. Based on such knowledge together with information obtained through model experiments, the human vocal organ was reconsidered mainly from the mechanical view point, and the roles of voice therapy and singing pedagogy were discussed in relation to phonosurgery. The vocal organ may not be an ideal musical organ and is rather vulnerable, but its potential is enormous.

Mechanical and dynamic aspects of voice production as related to voice therapy and phonosurgery.

PubMed

Isshiki, N

1998-06-01

Laryngeal framework surgery can change the position and tension of the vocal folds safely without direct surgical intervention in the vocal fold proper. Some 23 years of experience with phonosurgery have proved its usefulness in treating dysphonia related to unilateral vocal fold paralysis, vocal fold atrophy, and pitch-related dysphonias . Meanwhile, much information about the mechanism of voice production has been obtained through intraoperative findings of voice and fiberscopic examination of the larynx . Based on such knowledge together with information obtained through model experiments, the human vocal organ was reconsidered mainly from the mechanical view point, and the roles of voice therapy and singing pedagogy were discussed in relation to phonosurgery. The vocal organ may not be an ideal musical organ and is rather vulnerable, but its potential is enormous.

Who chooses a consumer-directed health plan?

PubMed

Barry, Colleen L; Cullen, Mark R; Galusha, Deron; Slade, Martin D; Busch, Susan H

2008-01-01

Consumer-directed health plans (CDHPs) hold the promise of reining in health spending by giving consumers a greater stake in health care purchasing, yet little is known about employers' experience with these products. In examining the characteristics of those selecting a CDHP offered by one large employer, we found stronger evidence of selection than has been identified in prior research. Our findings suggest that in the context of plan choice, CDHPs may offer little opportunity to greatly lower employers' cost burden, and they highlight concerns about the potential for risk segmentation and the value of conferring preferential tax treatment to CDHPs.

Who Chooses A Consumer-Directed Health Plan?

PubMed Central

Barry, Colleen L.; Cullen, Mark R.; Galusha, Deron; Slade, Martin D.; Busch, Susan H.

2012-01-01

Consumer-directed health plans (CDHPs) hold the promise of reining in health spending by giving consumers a greater stake in health care purchasing, yet little is known about employers’ experience with these products. In examining the characteristics of those selecting a CDHP offered by one large employer, we found stronger evidence of selection than has been identified in prior research. Our findings suggest that in the context of plan choice, CDHPs may offer little opportunity to greatly lower employers’ cost burden, and they highlight concerns about the potential for risk segmentation and the value of conferring preferential tax treatment to CDHPs. PMID:18997225

Quantity of 135I released from the AGR-1, AGR-2, and AGR-3/4 experiments and discovery of 131I at the FPMS traps during the AGR-3/4 experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scates, Dawn M.

2014-09-01

A series of three Advanced Gas Reactor (AGR) experiments have been conducted in the Advanced Test Reactor (ATR) at Idaho National Laboratory (INL). From 2006 through 2014, these experiments supported the development and qualification of the new U.S. tristructural isotropic (TRISO) particle fuel for Very High Temperature Reactors (VHTR). Each AGR experiment consisted of multiple fueled capsules, each plumbed for independent temperature control using a mix of helium and neon gases. The gas leaving a capsule was routed to individual Fission Product Monitor (FPM) detectors. For intact fuel particles, the TRISO particle coatings provide a substantial barrier to fission productmore » release. However, particles with failed coatings, whether because of a minute percentage of initially defective particles, those which fail during irradiation, or those designed to fail (DTF) particles, can release fission products to the flowing gas stream. Because reactive fission product elements like iodine and cesium quickly deposit on cooler capsule components and piping structures as the effluent gas leaves the reactor core, only the noble fission gas isotopes of Kr and Xe tend to reach FPM detectors. The FPM system utilizes High Purity Germanium (HPGe) detectors coupled with a thallium activated sodium iodide NaI(Tl) scintillator. The HPGe detector provides individual isotopic information, while the NaI(Tl) scintillator is used as a gross count rate meter. During irradiation, the 135mXe concentration reaching the FPM detectors is from both direct fission and by decay of the accumulated 135I. About 2.5 hours after irradiation (ten 15.3 minute 135mXe half lives) the directly produced 135mXe has decayed and only the longer lived 135I remains as a source. Decay systematics dictate that 135mXe will be in secular equilibrium with its 135I parent, such that its production rate very nearly equals the decay rate of the parent, and its concentration in the flowing gas stream will appear to decay with the parent half life. This equilibrium condition enables the determination of the amount of 135I released from the fuel particles by measurement of the 135mXe at the FPM following reactor shutdown. In this paper, the 135I released will be reported and compared to similar releases for noble gases as well as the unexpected finding of 131I deposition from intentional impure gas injection into capsule 11 of experiment AGR 3/4.« less

Pre-sowing Seed Treatments in Direct-seeded Early Rice: Consequences for Emergence, Seedling Growth and Associated Metabolic Events under Chilling Stress

NASA Astrophysics Data System (ADS)

Wang, Weiqin; Chen, Qian; Hussain, Saddam; Mei, Junhao; Dong, Huanglin; Peng, Shaobing; Huang, Jianliang; Cui, Kehui; Nie, Lixiao

2016-01-01

Double direct-seeding for double rice cropping is a simplified, labor saving, and efficient cropping system to improve multiple-crop index and total rice production in central China. However, poor crop establishment of direct-seeded early rice due to chilling stress is the main obstacle to wide spread of this system. A series of experiments were conducted to unravel the effects of pre-sowing seed treatments on emergence, seedling growth and associated metabolic events of direct-seeded early rice under chilling stress. Two seed priming treatments and two seed coating treatments were used in all the experiments. A non-treated control treatment was also maintained for comparison. In both the field and growth chamber studies, seed priming with selenium or salicylic acid significantly enhanced the emergence and seedling growth of rice compared with non-treated control. Nevertheless, such positive effects were not apparent for seed coating treatments. Better emergence and vigorous seedling growth of rice after seed priming was associated with enhanced α-amylase activity, higher soluble sugars contents, and greater respiration rate in primed rice seedlings under chilling stress. Taking together, these findings may provide new avenues for understanding and advancing priming-induced chilling tolerance in direct-seeded early rice in double rice cropping system.

Measurement of the muon beam direction and muon flux for the T2K neutrino experiment

NASA Astrophysics Data System (ADS)

Suzuki, K.; Aoki, S.; Ariga, A.; Ariga, T.; Bay, F.; Bronner, C.; Ereditato, A.; Friend, M.; Hartz, M.; Hiraki, T.; Ichikawa, A. K.; Ishida, T.; Ishii, T.; Juget, F.; Kikawa, T.; Kobayashi, T.; Kubo, H.; Matsuoka, K.; Maruyama, T.; Minamino, A.; Murakami, A.; Nakadaira, T.; Nakaya, T.; Nakayoshi, K.; Otani, M.; Oyama, Y.; Patel, N.; Pistillo, C.; Sakashita, K.; Sekiguchi, T.; Suzuki, S. Y.; Tada, S.; Yamada, Y.; Yamamoto, K.; Yokoyama, M.

2015-05-01

The Tokai-to-Kamioka (T2K) neutrino experiment measures neutrino oscillations by using an almost pure muon neutrino beam produced at the J-PARC accelerator facility. The T2K muon monitor was installed to measure the direction and stability of the muon beam which is produced in conjunction with the muon neutrino beam. The systematic error in the muon beam direction measurement was estimated, using data and MC simulation, to be 0.28 mrad. During beam operation, the proton beam has been controlled using measurements from the muon monitor and the direction of the neutrino beam has been tuned to within 0.3 mrad with respect to the designed beam-axis. In order to understand the muon beam properties, measurement of the absolute muon yield at the muon monitor was conducted with an emulsion detector. The number of muon tracks was measured to be (4.06± 0.05± 0.10)× 10^4cm^{-2} normalized with 4× 10^{11} protons on target with 250 kA horn operation. The result is in agreement with the prediction, which is corrected based on hadron production data.

Constraints on models for the Higgs boson with exotic spin and parity

NASA Astrophysics Data System (ADS)

Johnson, Emily Hannah

The production of a Higgs boson in association with a vector boson at the Tevatron offers a unique opportunity to study models for the Higgs boson with exotic spin J and parity P assignments. At the Tevatron the V H system is produced near threshold. Different JP assignments of the Higgs boson can be distinguished by examining the behavior of the cross section near threshold. The relatively low backgrounds at the Tevatron compared to the LHC put us in a unique position to study the direct decay of the Higgs boson to fermions. If the Higgs sector is more complex than predicted, studying the spin and parity of the Higgs boson in all decay modes is important. In this Thesis we will examine the WH → lnu bb¯ production and decay mode using 9.7 fb-1 of data collected by the D0 experiment in an attempt to derive constraints on models containing exotic values for the spin and parity of the Higgs boson. In particular, we will examine models for a Higgs boson with J P = 0- and JP = 2+. We use a likelihood ratio to quantify the degree to which our data are incompatible with exotic JP predictions for a range of possible production rates. Assuming the production cross section times branching ratio of the signals in the models considered is equal to the standard model prediction, the WH → lnu bb¯ mode alone is unable to reject either exotic model considered. We will also discuss the combination of the ZH → llbb¯, WH → lnubb¯, and V H → nunu bb¯ production modes at the D0 experiment and with the CDF experiment. When combining all three production modes at the D0 experiment we reject the JP = 0- and J P = 2+ hypotheses at the 97.6% CL and at the 99.0% CL, respectively, when assuming the signal production cross section times branching ratio is equal to the standard model predicted value. When combining with the CDF experiment we reject the JP = 0- and JP = 2 + hypotheses with significances of 5.0 standard deviations and 4.9 standard deviations, respectively.

Synergetic effect of yeast cell-surface expression of cellulase and expansin-like protein on direct ethanol production from cellulose

PubMed Central

2013-01-01

Background Numerous studies have examined the direct fermentation of cellulosic materials by cellulase-expressing yeast; however, ethanol productivity in these systems has not yet reached an industrial level. Certain microorganisms, such as the cellulolytic fungus Trichoderma reesei, produce expansin-like proteins, which have a cellulose-loosening effect that may increase the breakdown of cellulose. Here, to improve the direct conversion of cellulose to ethanol, yeast Saccharomyces cerevisiae co-displaying cellulase and expansin-like protein on the cell surface were constructed and examined for direct ethanol fermentation performance. Results The cellulase and expansin-like protein co-expressing strain showed 246 mU/g-wet cell of phosphoric acid swollen cellulose (PASC) degradation activity, which corresponded to 2.9-fold higher activity than that of a cellulase-expressing strain. This result clearly demonstrated that yeast cell-surface expressed cellulase and expansin-like protein act synergistically to breakdown cellulose. In fermentation experiments examining direct ethanol production from PASC, the cellulase and expansin-like protein co-expressing strain produced 3.4 g/L ethanol after 96 h of fermentation, a concentration that was 1.4-fold higher than that achieved by the cellulase-expressing strain (2.5 g/L). Conclusions The PASC degradation and fermentation ability of an engineered yeast strain was markedly improved by co-expressing cellulase and expansin-like protein on the cell surface. To our knowledge, this is the first report to demonstrate the synergetic effect of co-expressing cellulase and expansin-like protein on a yeast cell surface, which may be a promising strategy for constructing direct ethanol fermenting yeast from cellulose. PMID:23835302

Formation of particulate matter monitoring during combustion of wood pellete with additives

NASA Astrophysics Data System (ADS)

Palacka, Matej; Holubčík, Michal; Vician, Peter; Jandačka, Jozef

2016-06-01

Application additives into the material for the production of wood pellets achieve an improvement in some properties such as pellets ash flow temperature and abrasion resistance. Additives their properties influence the course of combustion, and have an impact on the results of issuance. The experiment were selected additives corn starch and dolomite. Wood pellets were produced in the pelleting press and pelletizing with the additives. Selected samples were tested for the production of particulate matter (PM) during their direct burn. The paper analyzing a process of producing wood pellets and his effect on the final properties.

Aqueous light driven hydrogen production by a Ru–ferredoxin–Co biohybrid

DOE PAGES

Soltau, Sarah R.; Niklas, Jens; Dahlberg, Peter D.; ...

2015-06-08

In this paper, we report the creation of a novel solar fuel biohybrid for light-driven H 2 production utilizing the native electron transfer protein ferredoxin (Fd) as a scaffold for binding of a ruthenium photosensitizer (PS) and a molecular cobaloxime catalyst (Co). Finally, EPR and transient optical experiments provide direct evidence of a long-lived (>1.5 ms) Ru(III)–Fd–Co(I) charge separated state formed via an electron relay through the Fd [2Fe–2S] cluster, initiating the catalytic cycle for 2H + + 2e - → H 2.

Photovoltaics - Where are we going?

NASA Technical Reports Server (NTRS)

Callaghan, W. T.

1984-01-01

The directions that will be followed for solar cell development, production and marketing are projected on the basis of experiences gained during the JPL's Flat-Plate Solar Array project. It is thought that a billion dollar market for Si ribbons can be established by 1990. Thin film technology will yield a product at $2 U.S./W at the end of the 1980s. R&D is growing more focused on central station photovoltaic generators, although the residential market may be the more suitable goal. The intermediate markets, e.g., schools, hospitals and shopping centers may be developed before the central stations.

Experimental and Numerical Observations of Hydrate Reformation during Depressurization in a Core-Scale Reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seol, Yongkoo; Myshakin, Evgeniy

2011-01-01

Gas hydrate has been predicted to reform around a wellbore during depressurization-based gas production from gas hydrate-bearing reservoirs. This process has an adverse effect on gas production rates and it requires time and sometimes special measures to resume gas flow to producing wells. Due to lack of applicable field data, laboratory scale experiments remain a valuable source of information to study hydrate reformation. In this work, we report laboratory experiments and complementary numerical simulations executed to investigate the hydrate reformation phenomenon. Gas production from a pressure vessel filled with hydrate-bearing sand was induced by depressurization with and without heat fluxmore » through the boundaries. Hydrate decomposition was monitored with a medical X-ray CT scanner and pressure and temperature measurements. CT images of the hydrate-bearing sample were processed to provide 3-dimensional data of heterogeneous porosity and phase saturations suitable for numerical simulations. In the experiments, gas hydrate reformation was observed only in the case of no-heat supply from surroundings, a finding consistent with numerical simulation. By allowing gas production on either side of the core, numerical simulations showed that initial hydrate distribution patterns affect gas distribution and flow inside the sample. This is a direct consequence of the heterogeneous pore network resulting in varying hydraulic properties of the hydrate-bearing sediment.« less

Defining process design space for monoclonal antibody cell culture.

PubMed

Abu-Absi, Susan Fugett; Yang, LiYing; Thompson, Patrick; Jiang, Canping; Kandula, Sunitha; Schilling, Bernhard; Shukla, Abhinav A

2010-08-15

The concept of design space has been taking root as a foundation of in-process control strategies for biopharmaceutical manufacturing processes. During mapping of the process design space, the multidimensional combination of operational variables is studied to quantify the impact on process performance in terms of productivity and product quality. An efficient methodology to map the design space for a monoclonal antibody cell culture process is described. A failure modes and effects analysis (FMEA) was used as the basis for the process characterization exercise. This was followed by an integrated study of the inoculum stage of the process which includes progressive shake flask and seed bioreactor steps. The operating conditions for the seed bioreactor were studied in an integrated fashion with the production bioreactor using a two stage design of experiments (DOE) methodology to enable optimization of operating conditions. A two level Resolution IV design was followed by a central composite design (CCD). These experiments enabled identification of the edge of failure and classification of the operational parameters as non-key, key or critical. In addition, the models generated from the data provide further insight into balancing productivity of the cell culture process with product quality considerations. Finally, process and product-related impurity clearance was evaluated by studies linking the upstream process with downstream purification. Production bioreactor parameters that directly influence antibody charge variants and glycosylation in CHO systems were identified.

KSC-97PC1462

NASA Image and Video Library

1997-09-15

United States Microgravity Payload-4 (USMP-4) experiments are prepared to be flown on Space Shuttle mission STS-87 in the Space Station Processing Facility at Kennedy Space Center (KSC). A technician is working on the Advanced Automated Directional Solidification Furnace (AADSF), which will be used by researchers to study the solidification of semiconductor materials in microgravity. Scientists will be able to better understand how microgravity influences the solidification process of these materials and develop better methods for controlling that process during future Space flights and Earth-based production. All STS-87 experiments are scheduled for launch on Nov. 19 from KSC

Microgravity

NASA Image and Video Library

2001-05-31

This diagram shows the general arrangement of the payloads to be carried by the multidisciplinary STS-107 Research-1 Space Shuttle mission in 2002. The Spacehab module will host experiments that require direct operation by the flight crew. Others with special requirements will be on the GAS Bridge Assembly sparning the payload bay. The Extended Duration Orbiter kit carries additional oxygen and hydrogen for the electricity-producing fuel cells. Research-1 experiments will cover space biology, life science, microgravity research, and commercial space product development, research sponsored by NASA's Office of Biological and Physical Research. An alternative view without callouts is available at 0101765.

Microgravity

NASA Image and Video Library

2001-05-31

Thisdiagram shows the general arrangement of the payloads to be carried by the multidisciplinary STS-107 Research-1 Space Shuttle mission in 2002. The Spacehab module will host experiments that require direct operation by the flight crew. Others with special requirements will be on the GAS Bridge Assembly sparning the payload bay. The Extended Duration Orbiter kit carries additional oxygen and hydrogen for the electricity-producing fuel cells. Research-1 experiments will cover space biology, life science, microgravity research, and commercial space product development, research sponsored by NASA's Office of Biological and Physical Research. An alternative view with callouts is available at 0101764.

STS-107 payload arrangement

NASA Technical Reports Server (NTRS)

2001-01-01

Thisdiagram shows the general arrangement of the payloads to be carried by the multidisciplinary STS-107 Research-1 Space Shuttle mission in 2002. The Spacehab module will host experiments that require direct operation by the flight crew. Others with special requirements will be on the GAS Bridge Assembly sparning the payload bay. The Extended Duration Orbiter kit carries additional oxygen and hydrogen for the electricity-producing fuel cells. Research-1 experiments will cover space biology, life science, microgravity research, and commercial space product development, research sponsored by NASA's Office of Biological and Physical Research. An alternative view with callouts is available at 0101764.

STS-107 payload arrangement

NASA Technical Reports Server (NTRS)

2001-01-01

This diagram shows the general arrangement of the payloads to be carried by the multidisciplinary STS-107 Research-1 Space Shuttle mission in 2002. The Spacehab module will host experiments that require direct operation by the flight crew. Others with special requirements will be on the GAS Bridge Assembly sparning the payload bay. The Extended Duration Orbiter kit carries additional oxygen and hydrogen for the electricity-producing fuel cells. Research-1 experiments will cover space biology, life science, microgravity research, and commercial space product development, research sponsored by NASA's Office of Biological and Physical Research. An alternative view without callouts is available at 0101765.

Reaction pathways involved in CH4 conversion on Pd/Al2O3 catalysts : TAP as a powerful tool for the elucidation of the effective role of the metal/support interface

NASA Astrophysics Data System (ADS)

Granger, Pascal

2016-02-01

Temporal Analysis of Products (TAP) reactor offers an alternative to draw direct structure/activity relationships checked on Natural Gas-fuelled Vehicle (NGV) catalysts Determination of accurate kinetic constants for methane adsorption from single pulse experiments and subsequent investigation of sequential surface reactions from alternative CH4/O2 pulse experiments provides a straightforward visualization of the involvement of the metal/support interface on freshly-prepared catalysts and the loss of this effect on aged single palladium based catalysts.

A Ramsey’s Method With Pulsed Neutrons for a T-Violation Experiment

PubMed Central

Masuda, Y.; Ino, T.; Muto, S.; Skoy, V.

2005-01-01

A Ramsey’s method with pulsed neutrons is discussed for neutron spin manipulation in a time reversal (T) symmetry violation experiment. The neutron spin (sn) is aligned to the direction of a vector product of the nuclear spin (I) and the neutron momentum (kn) for the measurement of a T-odd correlation term, which is represented as sn · (kn × I), during propagation through a polarized nuclear target. The phase control and amplitude modulation of separated oscillatory fields are discussed for the measurement of the T-odd correlation term. PMID:27308171

A Ramsey's Method With Pulsed Neutrons for a T-Violation Experiment.

PubMed

Masuda, Y; Ino, T; Muto, S; Skoy, V

2005-01-01

A Ramsey's method with pulsed neutrons is discussed for neutron spin manipulation in a time reversal (T) symmetry violation experiment. The neutron spin (s n) is aligned to the direction of a vector product of the nuclear spin ( I ) and the neutron momentum ( k n) for the measurement of a T-odd correlation term, which is represented as s n · ( k n × I ), during propagation through a polarized nuclear target. The phase control and amplitude modulation of separated oscillatory fields are discussed for the measurement of the T-odd correlation term.

A search for the production of direct leptons in nucleon-nucleus and nucleus-nucleus collisions. [Intermediate Energy Nuclear Physics Group, Dept. of Physics and Astronomy, Louisiana State Univ. , Baton Rouge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kirk, P.N.

1992-12-15

Activities included contributions to the AMY Collaboration, the transverse energy detector, the Di-Lepton Spectrometer, with emphasis on the single-lepton experiment. Elastic and inelastic scattering differential cross sections and total cross sections are shown for [pi][sup +] and [pi][sup [minus

CAUSE Resiliency (West Coast) Experiment Final Report

DTIC Science & Technology

2012-10-01

implemented in BCeMap and can therefore consume alerting messages direct from MASAS. This would solve the issue with the update frequency and speed of the...in production for use by the Provincial Emergency Operations Centres and brings together multiple static layers together with several dynamic data...executive order established the requirement for an “effective, reliable, integrated, flexible, and comprehensive system to alert and warn the

How Strong Is Your Coffee? The Influence of Visual Metaphors and Textual Claims on Consumers’ Flavor Perception and Product Evaluation

PubMed Central

Fenko, Anna; de Vries, Roxan; van Rompay, Thomas

2018-01-01

This study investigates the relative impact of textual claims and visual metaphors displayed on the product’s package on consumers’ flavor experience and product evaluation. For consumers, strength is one of the most important sensory attributes of coffee. The 2 × 3 between-subjects experiment (N = 123) compared the effects of visual metaphor of strength (an image of a lion located either on top or on the bottom of the package of coffee beans) and the direct textual claim (“extra strong”) on consumers’ responses to coffee, including product expectation, flavor evaluation, strength perception and purchase intention. The results demonstrate that both the textual claim and the visual metaphor can be efficient in communicating the product attribute of strength. The presence of the image positively influenced consumers’ product expectations before tasting. The textual claim increased the perception of strength of coffee and the purchase intention of the product. The location of the image also played an important role in flavor perception and purchase intention. The image located on the bottom of the package increased the perceived strength of coffee and purchase intention of the product compared to the image on top of the package. This result could be interpreted from the perspective of the grounded cognition theory, which suggests that a picture in the lower part of the package would automatically activate the “strong is heavy” metaphor. As heavy objects are usually associated with a position on the ground, this would explain why perceiving a visually heavy package would lead to the experience of a strong coffee. Further research is needed to better understand the relationships between a metaphorical image and its spatial position in food packaging design. PMID:29459840

Adaptive scallop height tool path generation for robot-based incremental sheet metal forming

NASA Astrophysics Data System (ADS)

Seim, Patrick; Möllensiep, Dennis; Störkle, Denis Daniel; Thyssen, Lars; Kuhlenkötter, Bernd

2016-10-01

Incremental sheet metal forming is an emerging process for the production of individualized products or prototypes in low batch sizes and with short times to market. In these processes, the desired shape is produced by the incremental inward motion of the workpiece-independent forming tool in depth direction and its movement along the contour in lateral direction. Based on this shape production, the tool path generation is a key factor on e.g. the resulting geometric accuracy, the resulting surface quality, and the working time. This paper presents an innovative tool path generation based on a commercial milling CAM package considering the surface quality and working time. This approach offers the ability to define a specific scallop height as an indicator of the surface quality for specific faces of a component. Moreover, it decreases the required working time for the production of the entire component compared to the use of a commercial software package without this adaptive approach. Different forming experiments have been performed to verify the newly developed tool path generation. Mainly, this approach serves to solve the existing conflict of combining the working time and the surface quality within the process of incremental sheet metal forming.

Novel Method of Production Decline Analysis

NASA Astrophysics Data System (ADS)

Xie, Shan; Lan, Yifei; He, Lei; Jiao, Yang; Wu, Yong

2018-02-01

ARPS decline curves is the most commonly used in oil and gas field due to its minimal data requirements and ease application. And prediction of production decline which is based on ARPS analysis rely on known decline type. However, when coefficient index are very approximate under different decline type, it is difficult to directly recognize decline trend of matched curves. Due to difficulties above, based on simulation results of multi-factor response experiments, a new dynamic decline prediction model is introduced with using multiple linear regression of influence factors. First of all, according to study of effect factors of production decline, interaction experimental schemes are designed. Based on simulated results, annual decline rate is predicted by decline model. Moreover, the new method is applied in A gas filed of Ordos Basin as example to illustrate reliability. The result commit that the new model can directly predict decline tendency without needing recognize decline style. From arithmetic aspect, it also take advantage of high veracity. Finally, the new method improves the evaluation method of gas well production decline in low permeability gas reservoir, which also provides technical support for further understanding of tight gas field development laws.

Alkyne–Aldehyde Reductive C–C Coupling through Ruthenium-Catalyzed Transfer Hydrogenation: Direct Regio- and Stereoselective Carbonyl Vinylation to Form Trisubstituted Allylic Alcohols in the Absence of Premetallated Reagents

PubMed Central

Leung, Joyce C.; Patman, Ryan L.; Sam, Brannon

2011-01-01

Nonsymmetric 1,2-disubstituted alkynes engage in reductive coupling to a variety of aldehydes under the conditions of ruthenium-catalyzed transfer hydrogenation by employing formic acid as the terminal reductant and delivering the products of carbonyl vinylation with good to excellent levels of regioselectivity and with complete control of olefin stereochemistry. As revealed in an assessment of the ruthenium counterion, iodide plays an essential role in directing the regioselectivity of C–C bond formation. Isotopic labeling studies corroborate reversible catalytic propargyl C–H oxidative addition in advance of the C–C coupling, and demonstrate that the C–C coupling products do not experience reversible dehydrogenation by way of enone intermediates. This transfer hydrogenation protocol enables carbonyl vinylation in the absence of stoichiometric metallic reagents. PMID:21953608

Electrocatalytic activity of ZnS nanoparticles in direct ethanol fuel cells

NASA Astrophysics Data System (ADS)

Bredol, Michael; Kaczmarek, Michał; Wiemhöfer, Hans-Dieter

2014-06-01

Low temperature fuel cells consuming ethanol without reformation would be a major step toward the use of renewable energy sources from biomass. However, the necessary electrodes and electrocatalysts still are far from being perfect and suffer from various poisoning and deactivation processes. This work describes investigations on systems using carbon/ZnS-based electrocatalysts for ethanol oxidation in complete membrane electrode assemblies (MEAs). MEAs were built on Nafion membranes with active masses prepared from ZnS nanoparticles and Vulcan carbon support. Under operation, acetic acid and acetaldehyde were identified and quantified as soluble oxidation products, whereas the amount of CO2 generated could not be quantified directly. Overall conversion efficiencies of up to 25% were estimated from cells operated over prolonged time. From polarization curves, interrupt experiments and analysis of reaction products, mass transport problems (concentration polarization) and breakthrough losses were found to be the main deficiencies of the ethanol oxidation electrodes fabricated so far.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anameric, B.; Kawatra, S.K.

The pig iron nugget process is gaining in importance as an alternative to the traditional blast furnace. Throughout the process, self-reducing-fluxing dried greenballs composed of iron ore concentrate, reducing-carburizing agent (coal), flux (limestone) and binder (bentonite) are heat-treated. During the heat treatment, dried greenballs are first transformed into direct reduced iron (DRI), then to transition direct reduced iron (TDRI) and finally to pig iron nuggets. The furnace temperature and/or residence time and the corresponding levels of carburization, reduction and metallization dictate these transformations. This study involved the determination of threshold furnace temperatures and residence times for completion of all ofmore » the transformation reactions and pig iron nugget production. The experiments involved the heat treatment of self-reducing-fluxing dried greenballs at various furnace temperatures and residence times. The products of these heat treatments were identified by utilizing optical microscopy, apparent density and microhardness measurements.« less

Measurement of nanoparticle size, suspension polydispersity, and stability using near-field optical trapping and light scattering (Conference Presentation)

NASA Astrophysics Data System (ADS)

Schein, Perry; O'Dell, Dakota; Erickson, David

2017-02-01

Nanoparticles are becoming ubiquitous in applications including diagnostic assays, drug delivery and therapeutics. However, there remain challenges in the quality control of these products. Here we present methods for the orthogonal measurement of these parameters by tracking the motion of the nanoparticle in all three special dimensions as it interacts with an optical waveguide. These simultaneous measurements from a single particle basis address some of the gaps left by current measurement technologies such as nanoparticle tracking analysis, ζ-potential measurements, and absorption spectroscopy. As nanoparticles suspended in a microfluidic channel interact with the evanescent field of an optical waveguide, they experience forces and resulting motion in three dimensions: along the propagation axis of the waveguide (x-direction) they are propelled by the optical forces, parallel to the plane of the waveguide and perpendicular to the optical propagation axis (y-direction) they experience an optical gradient force generated from the waveguide mode profile which confines them in a harmonic potential well, and normal to the surface of the waveguide they experience an exponential downward optical force balanced by the surface interactions that confines the particle in an asymmetric well. Building on our Nanophotonic Force Microscopy technique, in this talk we will explain how to simultaneously use the motion in the y-direction to estimate the size of the particle, the comparative velocity in the x-direction to measure the polydispersity of a particle population, and the motion in the z-direction to measure the potential energy landscape of the interaction, providing insight into the colloidal stability.

Development of Nurse Self-Concept in Nursing Students: The Effects of a Peer-Mentoring Experience.

PubMed

Ford, Yvonne

2015-09-01

Positive nurse self-concept has been shown to increase job productivity, retention, and job satisfaction. Student participation in peer-mentoring experiences has been shown to increase self-confidence and understanding of the role of the nurse leader. The Nurse Self-Concept Questionnaire (NSCQ) was used to measure the nurse self-concept of senior baccalaureate nursing students before and after completion of a peer-mentoring experience. Female students scored significantly higher on two subscales of the NSCQ than male students prior to the peer-mentoring experience. This difference was not seen after the experience. Mean changes in scores on all six dimensions of self-concept measured by the NSCQ were significantly higher after the mentoring experience. Further investigation of male students' experiences in clinical settings may be warranted. The experience of mentoring lower-level students offers practice for upper-level nursing students in providing direction, exercising leadership and management skills, and working as a member of the health care team. Copyright 2015, SLACK Incorporated.

Space Magnets Attracting Interest on Earth: Applications of Physical and Biological Techniques In the Study of Gravisensing and Response System of Plants

NASA Technical Reports Server (NTRS)

Hasenstein, Karl H.; Boody, April; Cox, David (Technical Monitor)

2002-01-01

The BioTube/Magnetic Field Apparatus (MFA) research is designed to provide insight into the organization and operation of the gravity sensing systems of plants and other small organisms. This experiment on STS-107 uses magnetic fields to manipulate sensory cells in plant roots, thus using magnetic fields as a tool to study gravity-related phenomena. The experiment will be located in the SPACEHAB module and is about the size of a household microwave oven. The goal of the experiment is to improve our understanding of the basic phenomenon of how plants respond to gravity. The BioTube/MFA experiment specifically examines how gravitational forces serve as a directional signal for growth in the low-gravity environment of space. As with all basic research, this study will contribute to an improved understanding of how plants grow and will have important implications for improving plant growth and productivity on Earth. In BioTube/MFA, magnetic fields will be used to determine whether the distribution of subcellular starch grains, called amyloplasts, within plant cells predicts the direction in which roots will grow and curve in microgravity.

Creating space plasma from the ground

NASA Astrophysics Data System (ADS)

Carlson, H. C.; Djuth, F. T.; Zhang, L. D.

2017-01-01

We have performed an experiment to compare as directly as realizable the ionization production rate by HF radio wave energy versus by solar EUV. We take advantage of the commonality that ionization production by both ground-based high-power HF radio waves and by solar EUV is driven by primary and secondary suprathermal electrons near and above 20 eV. Incoherent scatter radar (ISR) plasma-line amplitudes are used as a measure of suprathermal electron fluxes for ISR wavelengths near those for 430 MHz and are indeed a clean measure of such for those fluxes sufficiently weak to have negligible self-damping. We present data from an HF heating experiment on November 2015 at Arecibo, which even more directly confirm the only prior midlatitude estimate, of order 10% efficiency for conversion of HF energy to ionospheric ionization. We note the theoretical maximum possible is 1/3, while 1% or less reduces the question to near practical irrelevance. Our measurements explicitly confirm the prediction that radio-frequency production of artificial ionospheres can be practicable, even at midlatitudes. Furthermore, that this midlatitude efficiency is comparable to efficiencies measured at high latitudes (which include enhancements unique to high latitudes including magnetic zenith effect, gyrofrequency multiples, and double resonances) requires reexamination of current theoretical thinking about soft-electron acceleration processes in weakly magnetized plasmas. The implications are that electron acceleration by any of a variety of processes may be a fundamental underpinning to energy redistribution in space plasmas.

The comparison of BRDF model and validation of MCD43 products by the 2013 Dunhuang Gobi experiments

NASA Astrophysics Data System (ADS)

Li, Yuan; Rong, Zhi-guo; Zhang, Li-jun; Sun, Ling; Xu, Na

2014-11-01

BRDF has numerous applications in on-orbit satellites vicarious calibration. The 2013 Dunhuang Gobi surface directional reflectance measurements experiment were held during Aug. 20 to Aug. 28. In order to match the spatial resolution (0.25-1.25km) of meteorological satellites, 3*3 sample points were selected covering the 10*10km area. All the data were measured during (3 hours before and after) the noon without taking into account the large sun zenith angle because of the lack of the satellite passing through. Totally 9 groups of directional reflectance (DREF) were measured by the use of ASD (350-2500nm), standard reference board and a portable DREF measurement system. At each point, DREF were measured by different observation zenith angle (0, 20, 40 and 60 degree) and azimuth angle (0, 45, 90, 135, 180, 225, 270, 315 and 360 degree) in 30 minutes. Different BRDF models were selected such as Walthall, Sine Walthall, Hapke, Roujean and Ross-Li. The model coefficients were derived corresponding to the observed data. The relative differences (RD) of the models with respect to the measured values were calculated. The accuracy of MCD43 products in the Julian day of 233 and 241 were also validated. Results showed that Ross-Li model had the smallest RD. The RD between the DREF from MCD43 products and the measured values were 10.26%(233) and 8.96% (241)@550nm, respectively.

Optimization of poorly compactable drug tablets manufactured by direct compression using the mixture experimental design.

PubMed

Martinello, Tiago; Kaneko, Telma Mary; Velasco, Maria Valéria Robles; Taqueda, Maria Elena Santos; Consiglieri, Vladi O

2006-09-28

The poor flowability and bad compressibility characteristics of paracetamol are well known. As a result, the production of paracetamol tablets is almost exclusively by wet granulation, a disadvantageous method when compared to direct compression. The development of a new tablet formulation is still based on a large number of experiments and often relies merely on the experience of the analyst. The purpose of this study was to apply experimental design methodology (DOE) to the development and optimization of tablet formulations containing high amounts of paracetamol (more than 70%) and manufactured by direct compression. Nineteen formulations, screened by DOE methodology, were produced with different proportions of Microcel 102, Kollydon VA 64, Flowlac, Kollydon CL 30, PEG 4000, Aerosil, and magnesium stearate. Tablet properties, except friability, were in accordance with the USP 28th ed. requirements. These results were used to generate plots for optimization, mainly for friability. The physical-chemical data found from the optimized formulation were very close to those from the regression analysis, demonstrating that the mixture project is a great tool for the research and development of new formulations.

Quality by design approach: application of artificial intelligence techniques of tablets manufactured by direct compression.

PubMed

Aksu, Buket; Paradkar, Anant; de Matas, Marcel; Ozer, Ozgen; Güneri, Tamer; York, Peter

2012-12-01

The publication of the International Conference of Harmonization (ICH) Q8, Q9, and Q10 guidelines paved the way for the standardization of quality after the Food and Drug Administration issued current Good Manufacturing Practices guidelines in 2003. "Quality by Design", mentioned in the ICH Q8 guideline, offers a better scientific understanding of critical process and product qualities using knowledge obtained during the life cycle of a product. In this scope, the "knowledge space" is a summary of all process knowledge obtained during product development, and the "design space" is the area in which a product can be manufactured within acceptable limits. To create the spaces, artificial neural networks (ANNs) can be used to emphasize the multidimensional interactions of input variables and to closely bind these variables to a design space. This helps guide the experimental design process to include interactions among the input variables, along with modeling and optimization of pharmaceutical formulations. The objective of this study was to develop an integrated multivariate approach to obtain a quality product based on an understanding of the cause-effect relationships between formulation ingredients and product properties with ANNs and genetic programming on the ramipril tablets prepared by the direct compression method. In this study, the data are generated through the systematic application of the design of experiments (DoE) principles and optimization studies using artificial neural networks and neurofuzzy logic programs.

Taiwanese consumer survey data for investigating the role of information on equivalence of organic standards in directing food choice.

PubMed

Yeh, Ching-Hua; Hartmann, Monika; Hirsch, Stefan

2018-06-01

The presentation of credence attributes such as the product's origin or the production method has a significant influence on consumers' food purchase decisions. The dataset includes survey responses from a discrete choice experiment with 1309 food shoppers in Taiwan using the example of sweet pepper. The survey was carried out in 2014 in the three largest Taiwanese cities. It evaluates the impact of providing information on the equality of organic standards on consumers' preferences at the example of sweet pepper. Equality of organic standards implies that regardless of products' country-of-origin (COO) organic certifications are based on the same production regulation and managerial processes. Respondents were randomly allocated to the information treatment and the control group. The dataset contains the product choices of participants in both groups, as well as their sociodemographic information.

An ant colony optimization heuristic for an integrated production and distribution scheduling problem

NASA Astrophysics Data System (ADS)

Chang, Yung-Chia; Li, Vincent C.; Chiang, Chia-Ju

2014-04-01

Make-to-order or direct-order business models that require close interaction between production and distribution activities have been adopted by many enterprises in order to be competitive in demanding markets. This article considers an integrated production and distribution scheduling problem in which jobs are first processed by one of the unrelated parallel machines and then distributed to corresponding customers by capacitated vehicles without intermediate inventory. The objective is to find a joint production and distribution schedule so that the weighted sum of total weighted job delivery time and the total distribution cost is minimized. This article presents a mathematical model for describing the problem and designs an algorithm using ant colony optimization. Computational experiments illustrate that the algorithm developed is capable of generating near-optimal solutions. The computational results also demonstrate the value of integrating production and distribution in the model for the studied problem.

The Multi-GNSS Experiment (MGEX) of the International GNSS Service (IGS) - Achievements, prospects and challenges

NASA Astrophysics Data System (ADS)

Montenbruck, Oliver; Steigenberger, Peter; Prange, Lars; Deng, Zhiguo; Zhao, Qile; Perosanz, Felix; Romero, Ignacio; Noll, Carey; Stürze, Andrea; Weber, Georg; Schmid, Ralf; MacLeod, Ken; Schaer, Stefan

2017-04-01

Over the past five years, the International GNSS Service (IGS) has made continuous efforts to extend its service from GPS and GLONASS to the variety of newly established global and regional navigation satellite systems. This report summarizes the achievements and progress made in this period by the IGS Multi-GNSS Experiment (MGEX). The status and tracking capabilities of the IGS monitoring station network are presented and the multi-GNSS products derived from this resource are discussed. The achieved performance is assessed and related to the current level of space segment and user equipment characterization. While the performance of orbit and clock products for BeiDou, Galileo, and QZSS still lags behind the legacy GPS and GLONASS products, continued progress has been made since launch of the MGEX project and already enables use of the new constellations for precise point positioning, atmospheric research and other applications. Directions for further research are identified to fully integrate the new constellations into routine GNSS processing. Furthermore, the active support of GNSS providers is encouraged to assist the scientific community in the generation of fully competitive products for the new constellations.

Investigating the strategies for microbial production of trehalose from lignocellulosic sugars.

PubMed

Wu, Yifei; Wang, Jian; Shen, Xiaolin; Wang, Jia; Chen, Zhenya; Sun, Xinxiao; Yuan, Qipeng; Yan, Yajun

2018-03-01

Trehalose, a multi-functional and value-added disaccharide, can be efficiently biosynthesized from glucose by using a synergetic carbon utilization mechanism (SynCar) which coupled phosphoenolpyruvate (PEP) generation from the second carbon source with PEP-dependent phosphotransferase system (PTS) to promote non-catabolic use of glucose. Considering glucose and xylose present in large amounts in lignocellulosic sugars, we explored new strategies for conversion of both sugars into trehalose. Herein, we first attempted trehalose production from xylose directly, based on which, synergetic utilization of glucose, and xylose prompted by SynCar was implemented in engineered Escherichia coli. As the results, the final titer of trehalose reached 5.55 g/L in shake flask experiments. The conversion ratio or utilization efficiency of glucose or xylose to trehalose was around fourfold higher than that of the original strain (YW-3). This work not only demonstrated the possibility of directly converting xylose (C5 sugar) into trehalose (C12 disaccharide), but also suggested a promising strategy for trehalose production from lignocellulosic sugars for the first time. © 2017 Wiley Periodicals, Inc.

Production Experiences with the Cray-Enabled TORQUE Resource Manager

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ezell, Matthew A; Maxwell, Don E; Beer, David

High performance computing resources utilize batch systems to manage the user workload. Cray systems are uniquely different from typical clusters due to Cray s Application Level Placement Scheduler (ALPS). ALPS manages binary transfer, job launch and monitoring, and error handling. Batch systems require special support to integrate with ALPS using an XML protocol called BASIL. Previous versions of Adaptive Computing s TORQUE and Moab batch suite integrated with ALPS from within Moab, using PERL scripts to interface with BASIL. This would occasionally lead to problems when all the components would become unsynchronized. Version 4.1 of the TORQUE Resource Manager introducedmore » new features that allow it to directly integrate with ALPS using BASIL. This paper describes production experiences at Oak Ridge National Laboratory using the new TORQUE software versions, as well as ongoing and future work to improve TORQUE.« less

A Dependence of Charmed Meson Production (in Portuguese)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alves, Gilvan Augusto

One report is presented of a recent direct measurement of the nucleon number (A) dependence of the production cross sections for the charmed mesonsmore » $D^0$ and $D^+$ using $$\\pi^+_{-}$$ and $$K^+_{-}$$ beams incident on a segmented target of Be, Al, Cu and W. The data derive from the experiment E769 - Hadroproductlon of Charm at Fermilab. The experimental apparatus is described together with the following analysis. Starting from a sample of -1500 D mesons in the range of $$O< x_{f} <1$$, the data are found to be well described by the parameterization $$\\sigma_{A}$$ = $$\\sigma_{O}$$ , with $$\\alpha = 0.99 \\pm 0.03$$. The $$x_f$$ dependence of $$\\alpha$$ is examined and the results obtained are compared with those of other .experiments and wl th -theoretical expectations based on perturbatlve QCD and on an EMC like model of nuclear shadowing« less

Mouth-watering words: Articulatory inductions of eating-like mouth movements increase perceived food palatability.

PubMed

Topolinski, Sascha; Boecker, Lea

2016-04-01

We explored the impact of consonantal articulation direction of names for foods on expected palatability for these foods (total N = 256). Dishes (Experiments 1-2) and food items (Experiment 3) were labeled with names whose consonants either wandered from the front to the back of the mouth (inward, e.g., PASOKI) or from the back to the front of the mouth (outward; e.g., KASOPI). Because inward (outward) wandering consonant sequences trigger eating-like (expectoration-like) mouth movements, dishes and foods were rated higher in palatability when they bore an inward compared to an outward wandering name. This effect occurred already under silent reading and for hungry and satiated participants alike. As a boundary condition, this articulation effect did occur when also additional visual information on the product was given (Experiment 3), but vanished when this visual information was too vivid and rich in competing palatability cues (Experiment 2). Future marketing can exploit this effect by increasing the appeal of food products by using inward wandering brand names, that is, names that start with the lips and end in the throat. Copyright © 2016 Elsevier Ltd. All rights reserved.

Solenoid Magnet System for the Fermilab Mu2e Experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lamm, M. J.; Andreev, N.; Ambrosio, G.

2011-12-14

The Fermilab Mu2e experiment seeks to measure the rare process of direct muon to electron conversion in the field of a nucleus. Key to the design of the experiment is a system of three superconducting solenoids; a muon production solenoid (PS) which is a 1.8 m aperture axially graded solenoid with a peak field of 5 T used to focus secondary pions and muons from a production target located in the solenoid aperture; an 'S shaped' transport solenoid (TS) which selects and transports the subsequent muons towards a stopping target; a detector solenoid (DS) which is an axially graded solenoidmore » at the upstream end to focus transported muons to a stopping target, and a spectrometer solenoid at the downstream end to accurately measure the momentum of the outgoing conversion elections. The magnetic field requirements, the significant magnetic coupling between the solenoids, the curved muon transport geometry and the large beam induced energy deposition into the superconducting coils pose significant challenges to the magnetic, mechanical, and thermal design of this system. In this paper a conceptual design for the magnetic system which meets the Mu2e experiment requirements is presented.« less

Extracting the Electron-Ion Temperature Relaxation Rate from Ion Stopping Experiments

NASA Astrophysics Data System (ADS)

Grabowski, Paul E.; Frenje, Johan A.; Benedict, Lorin X.

2016-10-01

Direct measurement of i-e equilibration rates at ICF-relevant conditions is a big challenge, as it is difficult to differentiate from other sinks and sources of energy, such as heat conduction and pdV work. Another method is to use information from ion stopping experiments. Such experiments at the OMEGA laser have made precision energy loss measurements of fusion products at these conditions. Combined with the multimonochromatic x-ray imager technique, which gives temporally and spatially resolved electron temperature and density, we have a robust stopping experiment. We propose to use such stopping measurements to assess the i-e temperature relaxation rate, since both processes involve energy exchange between electrons and ions. We require that the fusion products are 1) much faster than the thermal ions so that i-i collisions are negligible compared to i-e collisions and 2) slower than the thermal electrons so that the stopping obeys a linear friction law. Then the Coulomb logarithms associated with ion stopping and i-e temperature relaxation rate are identical and a measurement of the former provides the latter. Prepared by LLNL under Contract DE-AC52-07NA27344.

Electron-driven and thermal chemistry during water-assisted purification of platinum nanomaterials generated by electron beam induced deposition

PubMed Central

Warneke, Jonas; Kopyra, Janina

2018-01-01

Focused electron beam induced deposition (FEBID) is a versatile tool for the direct-write fabrication of nanostructures on surfaces. However, FEBID nanostructures are usually highly contaminated by carbon originating from the precursor used in the process. Recently, it was shown that platinum nanostructures produced by FEBID can be efficiently purified by electron irradiation in the presence of water. If such processes can be transferred to FEBID deposits produced from other carbon-containing precursors, a new general approach to the generation of pure metallic nanostructures could be implemented. Therefore this study aims to understand the chemical reactions that are fundamental to the water-assisted purification of platinum FEBID deposits generated from trimethyl(methylcyclopentadienyl)platinum(IV) (MeCpPtMe3). The experiments performed under ultrahigh vacuum conditions apply a combination of different desorption experiments coupled with mass spectrometry to analyse reaction products. Electron-stimulated desorption monitors species that leave the surface during electron exposure while post-irradiation thermal desorption spectrometry reveals products that evolve during subsequent thermal treatment. In addition, desorption of volatile products was also observed when a deposit produced by electron exposure was subsequently brought into contact with water. The results distinguish between contributions of thermal chemistry, direct chemistry between water and the deposit, and electron-induced reactions that all contribute to the purification process. We discuss reaction kinetics for the main volatile products CO and CH4 to obtain mechanistic information. The results provide novel insights into the chemistry that occurs during purification of FEBID nanostructures with implications also for the stability of the carbonaceous matrix of nanogranular FEBID materials under humid conditions. PMID:29441253

Degradation of emerging contaminants from water under natural sunlight: The effect of season, pH, humic acids and nitrate and identification of photodegradation by-products.

PubMed

Koumaki, Elena; Mamais, Daniel; Noutsopoulos, Constantinos; Nika, Maria-Christina; Bletsou, Anna A; Thomaidis, Nikolaos S; Eftaxias, Alexander; Stratogianni, Georgia

2015-11-01

Both photodegradation and hydrolysis of non-steroidal anti-inflammatory drugs (NSAIDs) and endocrine disrupting chemicals (EDCs) were investigated in order to evaluate their photochemical fate in aquatic environment and to assess the effect of season and specific characteristics of water (pH, humic acids and nitrate concentration) on the removal of target EDCs and NSAIDs through photodegradation. An additional objective was the identification of the photodegradation by-products of specific NSAIDs and their dependence on irradiation time. Selected compounds' transformation was investigated under natural sunlight radiation while control experiments were conducted in the dark. As expected, most of compounds' degradation rate decreased with decreasing light intensity between two different experimental periods. Most of the tested compounds exhibited different rates of degradation during direct and indirect photolysis. The degradation rate of the selected compounds increased in the presence of NO3(-) and the photodegradation rate was higher for some compounds in alkaline than in acidic solution. The effect of humic acids' presence in the water depends on the absorbance spectrum of the compound and the produced photosensitizers. More specifically, humic acids act as inner filter toward most of the selected NSAIDs and as photosensitizers toward most of the EDCs. The results of the irradiation experiments in the presence of both humic acids and NO3(-), indicate that the direct photolysis is much more efficient than indirect photochemical processes. Finally, several degradation by-products of ketoprofen and diclofenac were identified in the samples, exposed to sunlight. The dependence of these by-products on radiation time is also demonstrated. Copyright © 2015 Elsevier Ltd. All rights reserved.

Scaling up the diversity-resilience relationship with trait databases and remote sensing data: the recovery of productivity after wildfire.

PubMed

Spasojevic, Marko J; Bahlai, Christie A; Bradley, Bethany A; Butterfield, Bradley J; Tuanmu, Mao-Ning; Sistla, Seeta; Wiederholt, Ruscena; Suding, Katharine N

2016-04-01

Understanding the mechanisms underlying ecosystem resilience - why some systems have an irreversible response to disturbances while others recover - is critical for conserving biodiversity and ecosystem function in the face of global change. Despite the widespread acceptance of a positive relationship between biodiversity and resilience, empirical evidence for this relationship remains fairly limited in scope and localized in scale. Assessing resilience at the large landscape and regional scales most relevant to land management and conservation practices has been limited by the ability to measure both diversity and resilience over large spatial scales. Here, we combined tools used in large-scale studies of biodiversity (remote sensing and trait databases) with theoretical advances developed from small-scale experiments to ask whether the functional diversity within a range of woodland and forest ecosystems influences the recovery of productivity after wildfires across the four-corner region of the United States. We additionally asked how environmental variation (topography, macroclimate) across this geographic region influences such resilience, either directly or indirectly via changes in functional diversity. Using path analysis, we found that functional diversity in regeneration traits (fire tolerance, fire resistance, resprout ability) was a stronger predictor of the recovery of productivity after wildfire than the functional diversity of seed mass or species richness. Moreover, slope, elevation, and aspect either directly or indirectly influenced the recovery of productivity, likely via their effect on microclimate, while macroclimate had no direct or indirect effects. Our study provides some of the first direct empirical evidence for functional diversity increasing resilience at large spatial scales. Our approach highlights the power of combining theory based on local-scale studies with tools used in studies at large spatial scales and trait databases to understand pressing environmental issues. © 2015 John Wiley & Sons Ltd.

Changes in ecosystem resilience detected in automated measures of ecosystem metabolism during a whole-lake manipulation

PubMed Central

Batt, Ryan D.; Carpenter, Stephen R.; Cole, Jonathan J.; Pace, Michael L.; Johnson, Robert A.

2013-01-01

Environmental sensor networks are developing rapidly to assess changes in ecosystems and their services. Some ecosystem changes involve thresholds, and theory suggests that statistical indicators of changing resilience can be detected near thresholds. We examined the capacity of environmental sensors to assess resilience during an experimentally induced transition in a whole-lake manipulation. A trophic cascade was induced in a planktivore-dominated lake by slowly adding piscivorous bass, whereas a nearby bass-dominated lake remained unmanipulated and served as a reference ecosystem during the 4-y experiment. In both the manipulated and reference lakes, automated sensors were used to measure variables related to ecosystem metabolism (dissolved oxygen, pH, and chlorophyll-a concentration) and to estimate gross primary production, respiration, and net ecosystem production. Thresholds were detected in some automated measurements more than a year before the completion of the transition to piscivore dominance. Directly measured variables (dissolved oxygen, pH, and chlorophyll-a concentration) related to ecosystem metabolism were better indicators of the approaching threshold than were the estimates of rates (gross primary production, respiration, and net ecosystem production); this difference was likely a result of the larger uncertainties in the derived rate estimates. Thus, relatively simple characteristics of ecosystems that were observed directly by the sensors were superior indicators of changing resilience. Models linked to thresholds in variables that are directly observed by sensor networks may provide unique opportunities for evaluating resilience in complex ecosystems. PMID:24101479

Changes in ecosystem resilience detected in automated measures of ecosystem metabolism during a whole-lake manipulation.

PubMed

Batt, Ryan D; Carpenter, Stephen R; Cole, Jonathan J; Pace, Michael L; Johnson, Robert A

2013-10-22

Environmental sensor networks are developing rapidly to assess changes in ecosystems and their services. Some ecosystem changes involve thresholds, and theory suggests that statistical indicators of changing resilience can be detected near thresholds. We examined the capacity of environmental sensors to assess resilience during an experimentally induced transition in a whole-lake manipulation. A trophic cascade was induced in a planktivore-dominated lake by slowly adding piscivorous bass, whereas a nearby bass-dominated lake remained unmanipulated and served as a reference ecosystem during the 4-y experiment. In both the manipulated and reference lakes, automated sensors were used to measure variables related to ecosystem metabolism (dissolved oxygen, pH, and chlorophyll-a concentration) and to estimate gross primary production, respiration, and net ecosystem production. Thresholds were detected in some automated measurements more than a year before the completion of the transition to piscivore dominance. Directly measured variables (dissolved oxygen, pH, and chlorophyll-a concentration) related to ecosystem metabolism were better indicators of the approaching threshold than were the estimates of rates (gross primary production, respiration, and net ecosystem production); this difference was likely a result of the larger uncertainties in the derived rate estimates. Thus, relatively simple characteristics of ecosystems that were observed directly by the sensors were superior indicators of changing resilience. Models linked to thresholds in variables that are directly observed by sensor networks may provide unique opportunities for evaluating resilience in complex ecosystems.

Whisker/Cone growth on the thermal control surfaces experiment no. S0069

NASA Technical Reports Server (NTRS)

Zwiener, James M.; Coston, James E., Jr.; Miller, Edgar R.; Mell, Richard J.; Wilkes, Donald R.

1995-01-01

An unusual surface 'growth' was found during scanning electron microscope (SEM) investigations of the Thermal Control Surface Experiment (TCSE) S0069 front thermal cover. This 'growth' is similar to the cone type whisker growth phenomena as studied by G. K. Wehner beginning in the 1960's. Extensive analysis has identified the most probable composition of the whiskers to be a silicate type glass. Sources of the growth material are outgassing products from the experiment and orbital atomic oxygen, which occurs naturally at the orbital altitudes of the LDEF mission in the form of neutral atomic oxygen. The highly ordered symmetry and directionality of the whiskers are attributed to the long term (5.8 year) stable flight orientation of the LDEF.

Direct and Indirect Costs of Chronic and Episodic Migraine in the United States: A Web-Based Survey.

PubMed

Messali, Andrew; Sanderson, Joanna C; Blumenfeld, Andrew M; Goadsby, Peter J; Buse, Dawn C; Varon, Sepideh F; Stokes, Michael; Lipton, Richard B

2016-02-01

The objective of this study was to compare the societal direct and indirect costs of chronic and episodic migraine in the United States. Episodic and chronic migraine are distinguished by the frequency of headache-days. Chronic migraine has a greater overall impact on quality of life than does episodic migraine. Individuals with chronic migraine also use more healthcare resources (resulting in higher direct costs) and experience greater decreases in productivity (resulting in higher indirect costs) than those with episodic migraine as shown in the American Migraine Prevalence and Prevention (AMPP) Study. The International Burden of Migraine Study utilized a web-based questionnaire to elicit data on several topics related to the burden of migraine illness, including health resource utilization and productivity losses. Potential survey participants were identified by Synovate Healthcare (Chicago, IL, USA) from a pool of registered panelists from various countries. The panelists were screened online to determine eligibility and to identify individuals with migraine (episodic or chronic), based on reported symptoms. Participants from the United States were divided into episodic and chronic migraine groups, based on reported headache-day per month frequency. Direct and indirect costs were estimated by applying estimated unit costs to reported headache-related productivity losses and resource use. Costs were compared between participants with episodic and chronic migraine. Mean [standard deviation] total annual cost of headache among people with chronic migraine ($8243 [$10,646]) was over three times that of episodic migraine ($2649 [$4634], P < .001). Participants with chronic migraine had significantly greater direct medical costs ($4943 [$6382]) and indirect (lost productivity) costs ($3300 [$6907]) than did participants with episodic migraine (direct, $1705 [$3591]; indirect, $943 [$2084]) (P < .001 for each). Unlike previous findings, direct medical costs constituted the majority of total headache-related costs for both chronic migraine (60.0%, $4943 of $8243) and episodic migraine (64.3%, $1705 of $2649) participants. A large portion of direct medical costs are attributable to pharmaceutical utilization among both chronic migraine (80%, $3925 of 4943) and episodic migraine (70%, $1196 of $1705) participants. The results of this study build on previous results of the AMPP Study, demonstrating that headache-related direct, indirect, and total costs are significantly greater among individuals with chronic migraine than with episodic migraine in the United States. © 2016 American Headache Society.

Direct effect of acid rain on leaf chlorophyll content of terrestrial plants in China.

PubMed

Du, Enzai; Dong, Dan; Zeng, Xuetong; Sun, Zhengzhong; Jiang, Xiaofei; de Vries, Wim

2017-12-15

Anthropogenic emissions of acid precursors in China have resulted in widespread acid rain since the 1980s. Although efforts have been made to assess the indirect, soil mediated ecological effects of acid rain, a systematic assessment of the direct foliage injury by acid rain across terrestrial plants is lacking. Leaf chlorophyll content is an important indicator of direct foliage damage and strongly related to plant productivity. We synthesized data from published literature on experiments of simulated acid rain, by directly exposing plants to acid solutions with varying pH levels, to assess the direct effect of acid rain on leaf chlorophyll content across 67 terrestrial plants in China. Our results indicate that acid rain substantially reduces leaf chlorophyll content by 6.71% per pH unit across the recorded plant species. The direct reduction of leaf chlorophyll content due to acid rain exposure showed no significant difference across calcicole, ubiquist or calcifuge species, implying that soil acidity preference does not influence the sensitivity to leaf injury by acid rain. On average, the direct effects of acid rain on leaf chlorophyll on trees, shrubs and herbs were comparable. The effects, however varied across functional groups and economic use types. Specifically, leaf chlorophyll content of deciduous species was more sensitive to acid rain in comparison to evergreen species. Moreover, vegetables and fruit trees were more sensitive to acid rain than other economically used plants. Our findings imply a potential production reduction and economic loss due to the direct foliage damage by acid rain. Copyright © 2017 Elsevier B.V. All rights reserved.

Oxygen production by pyrolysis of lunar regolith

NASA Technical Reports Server (NTRS)

Senior, Constance L.

1991-01-01

Oxygen was identified as the most important product of initial lunar materials processing efforts. A source of oxygen on the Moon provides an alternative to the costly transport of propellant to the Moon or to low earth orbit. Pyrolysis, or vapor-phase reduction, involves heating a feedstock to temperatures sufficient to decompose the constituent metal oxides and release oxygen. The process relies on the vaporization of metal oxides in the form of reduced suboxides or atomic species. The reduced species must then be condensed without re-oxidizing, yielding oxygen in the gas phase. The feasibility of obtaining oxygen from common lunar minerals was demonstrated using solar furnace experiments. These results are discussed together with chemical equilibrium models which were extended to include the multicomponent oxides used in experiments. For the first time, both experiments and theoretical models dealt with the complex oxides that make up potential lunar feedstocks. Two major conclusions are drawn from this preliminary work. First, unbeneficiated regolith is a suitable feedstock for pyrolysis. Second, the process can operate at moderate temperatures, circa 2000 K, which could be supplied by direct solar or electrical energy. In addition to these advantages in choice of feedstock and energy source, the pyrolysis process requires no chemicals or reagents, making it an attractive process for lunar oxygen production.

Probing the independence of formant control using altered auditory feedback

PubMed Central

MacDonald, Ewen N.; Purcell, David W.; Munhall, Kevin G.

2011-01-01

Two auditory feedback perturbation experiments were conducted to examine the nature of control of the first two formants in vowels. In the first experiment, talkers heard their auditory feedback with either F1 or F2 shifted in frequency. Talkers altered production of the perturbed formant by changing its frequency in the opposite direction to the perturbation but did not produce a correlated alteration of the unperturbed formant. Thus, the motor control system is capable of fine-grained independent control of F1 and F2. In the second experiment, a large meta-analysis was conducted on data from talkers who received feedback where both F1 and F2 had been perturbed. A moderate correlation was found between individual compensations in F1 and F2 suggesting that the control of F1 and F2 is processed in a common manner at some level. While a wide range of individual compensation magnitudes were observed, no significant correlations were found between individuals’ compensations and vowel space differences. Similarly, no significant correlations were found between individuals’ compensations and variability in normal vowel production. Further, when receiving normal auditory feedback, most of the population exhibited no significant correlation between the natural variation in production of F1 and F2. PMID:21361452

Energy dependence of J/ψ production in Au + Au collisions at √{sNN} = 39 , 62.4 and 200GeV

NASA Astrophysics Data System (ADS)

Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Ajitanand, N. N.; Alekseev, I.; Anderson, D. M.; Aoyama, R.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Ashraf, M. U.; Attri, A.; Averichev, G. S.; Bai, X.; Bairathi, V.; Behera, A.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Bouchet, J.; Brandenburg, J. D.; Brandin, A. V.; Brown, D.; Bunzarov, I.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Chakaberia, I.; Chaloupka, P.; Chang, Z.; Chankova-Bunzarova, N.; Chatterjee, A.; Chattopadhyay, S.; Chen, X.; Chen, J. H.; Chen, X.; Cheng, J.; Cherney, M.; Christie, W.; Contin, G.; Crawford, H. J.; Das, S.; De Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; Didenko, L.; Dilks, C.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Elsey, N.; Engelage, J.; Eppley, G.; Esha, R.; Esumi, S.; Evdokimov, O.; Ewigleben, J.; Eyser, O.; Fatemi, R.; Fazio, S.; Federic, P.; Federicova, P.; Fedorisin, J.; Feng, Z.; Filip, P.; Finch, E.; Fisyak, Y.; Flores, C. E.; Fujita, J.; Fulek, L.; Gagliardi, C. A.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Hamad, A. I.; Hamed, A.; Harlenderova, A.; Harris, J. W.; He, L.; Heppelmann, S.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Horvat, S.; Huang, B.; Huang, H. Z.; Huang, T.; Huang, X.; Humanic, T. J.; Huo, P.; Igo, G.; Jacobs, W. W.; Jentsch, A.; Jia, J.; Jiang, K.; Jowzaee, S.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Khan, Z.; Kikoła, D. P.; Kisel, I.; Kisiel, A.; Kochenda, L.; Kocmanek, M.; Kollegger, T.; Kosarzewski, L. K.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kulathunga, N.; Kumar, L.; Kvapil, J.; Kwasizur, J. H.; Lacey, R.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; Li, Y.; Li, X.; Li, W.; Li, C.; Lidrych, J.; Lin, T.; Lisa, M. A.; Liu, Y.; Liu, H.; Liu, F.; Liu, P.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, S.; Luo, X.; Ma, G. L.; Ma, L.; Ma, Y. G.; Ma, R.; Magdy, N.; Majka, R.; Mallick, D.; Margetis, S.; Markert, C.; Matis, H. S.; Meehan, K.; Mei, J. C.; Miller, Z. W.; Minaev, N. G.; Mioduszewski, S.; Mishra, D.; Mizuno, S.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nasim, Md.; Nayak, T. K.; Nelson, J. M.; Nie, M.; Nigmatkulov, G.; Niida, T.; Nogach, L. V.; Nonaka, T.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Okorokov, V. A.; Olvitt, D.; Page, B. S.; Pak, R.; Pandit, Y.; Panebratsev, Y.; Pawlik, B.; Pei, H.; Perkins, C.; Pile, P.; Pluta, J.; Poniatowska, K.; Porter, J.; Posik, M.; Pruthi, N. K.; Przybycien, M.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Ray, R. L.; Reed, R.; Rehbein, M. J.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Roth, J. D.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Salur, S.; Sandweiss, J.; Saur, M.; Schambach, J.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Schweid, B. R.; Seger, J.; Sergeeva, M.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, A.; Sharma, M. K.; Shen, W. Q.; Shi, S. S.; Shi, Z.; Shou, Q. Y.; Sichtermann, E. P.; Sikora, R.; Simko, M.; Singha, S.; Skoby, M. J.; Smirnov, N.; Smirnov, D.; Solyst, W.; Song, L.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Strikhanov, M.; Stringfellow, B.; Sugiura, T.; Sumbera, M.; Summa, B.; Sun, X.; Sun, Y.; Sun, X. M.; Surrow, B.; Svirida, D. N.; Tang, A. H.; Tang, Z.; Taranenko, A.; Tarnowsky, T.; Tawfik, A.; Thäder, J.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Todoroki, T.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Tripathy, S. K.; Trzeciak, B. A.; Tsai, O. D.; Ullrich, T.; Underwood, D. G.; Upsal, I.; Van Buren, G.; van Nieuwenhuizen, G.; Vasiliev, A. N.; Videbæk, F.; Vokal, S.; Voloshin, S. A.; Vossen, A.; Wang, G.; Wang, Y.; Wang, F.; Wang, Y.; Webb, J. C.; Webb, G.; Wen, L.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y.; Xiao, Z. G.; Xie, W.; Xie, G.; Xu, J.; Xu, N.; Xu, Q. H.; Xu, Y. F.; Xu, Z.; Yang, Y.; Yang, Q.; Yang, C.; Yang, S.; Ye, Z.; Ye, Z.; Yi, L.; Yip, K.; Yoo, I.-K.; Yu, N.; Zbroszczyk, H.; Zha, W.; Zhang, Z.; Zhang, X. P.; Zhang, J. B.; Zhang, S.; Zhang, J.; Zhang, Y.; Zhang, J.; Zhang, S.; Zhao, J.; Zhong, C.; Zhou, L.; Zhou, C.; Zhu, X.; Zhu, Z.; Zyzak, M.; STAR Collaboration

2017-08-01

The inclusive J / ψ transverse momentum spectra and nuclear modification factors are reported at mid-rapidity (| y | < 1.0) in Au + Au collisions at √{sNN} = 39, 62.4 and 200 GeV taken by the STAR experiment. A suppression of J / ψ production, with respect to the production in p + p scaled by the number of binary nucleon-nucleon collisions, is observed in central Au + Au collisions at these three energies. No significant energy dependence of nuclear modification factors is found within uncertainties. The measured nuclear modification factors can be described by model calculations that take into account both suppression of direct J / ψ production due to the color screening effect and J / ψ regeneration from recombination of uncorrelated charm-anticharm quark pairs.

JPRS Report, China, Red Flag, Number 3, 1 Febrary 1988

DTIC Science & Technology

1988-04-19

of the Agricultural Scale Operational Experiment in Shunyi County, Beijing [Zhao Shufeng, et al.J : 21 An Investigation on the Specialized Market ...people who are skilled in three professions (namely, economists, accoun- tants, and lawyers) in our foreign economic affairs. Many children of...original 60-plus mandatory production plans have been reduced to 6, and the proportions of raw materials the enterprises directly obtain from the market

REVIEWS OF TOPICAL PROBLEMS: The search for dark matter particles

NASA Astrophysics Data System (ADS)

Ryabov, Vladimir A.; Tsarev, Vladimir A.; Tskhovrebov, Andrei M.

2008-11-01

Evidence of dark matter in the Universe is discussed and the most popular candidates for dark matter particles are reviewed. The review is mainly devoted to numerous experiments, both underway and planned, on the search for dark matter particles. Various experimental methods are discussed, including those involving direct registration of dark matter particles with the detector and those where the products of dark matter decay and annihilation are registered.

INVESTIGATION OF DENSITY EFFECT IN SOLIDS AND GASES.

DTIC Science & Technology

electron-positron pair production by 150 MeV electrons. (5) Investiga tion of the density effect in C, Al, Fe, Cu, Ni, Ag, Ta, and Au. (Author)...This report describes the results obtained for the following experiments: (1) The pressure dependence of ionization by relativistic elec trons. (2...Ionization by relativistic particles in helium-hydrogen gas mixtures. (3) Investiga tion of the operation of secondary emission monitors. (4) Direct

Exploring the relationship between nature sounds, connectedness to nature, mood and willingness to buy sustainable food: A retail field experiment.

PubMed

Spendrup, Sara; Hunter, Erik; Isgren, Ellinor

2016-05-01

Nature sounds are increasingly used by some food retailers to enhance in-store ambiance and potentially even influence sustainable food choices. An in-store, 2 × 3 between-subject full factorial experiment conducted on 627 customers over 12 days tested whether nature sound directly and indirectly influenced willingness to buy (WTB) sustainable foods. The results show that nature sounds positively and directly influence WTB organic foods in groups of customers (men) that have relatively low initial intentions to buy. Indirectly, we did not find support for the effect of nature sound on influencing mood or connectedness to nature (CtN). However, we show that information on the product's sustainability characteristics moderates the relationship between CtN and WTB in certain groups. Namely, when CtN is high, sustainability information positively moderated WTB both organic and climate friendly foods in men. Conversely, when CtN was low, men expressed lower WTB organic and climate friendly foods than identical, albeit conventionally labelled products. Consequently, our study concludes that nature sounds might be an effective, yet subtle in-store tool to use on groups of consumers who might otherwise respond negatively to more overt forms of sustainable food information. Copyright © 2016 Elsevier Ltd. All rights reserved.

The metabolic response of marine copepods to environmental warming and ocean acidification in the absence of food

NASA Astrophysics Data System (ADS)

Mayor, Daniel J.; Sommer, Ulf; Cook, Kathryn B.; Viant, Mark R.

2015-09-01

Marine copepods are central to the productivity and biogeochemistry of marine ecosystems. Nevertheless, the direct and indirect effects of climate change on their metabolic functioning remain poorly understood. Here, we use metabolomics, the unbiased study of multiple low molecular weight organic metabolites, to examine how the physiology of Calanus spp. is affected by end-of-century global warming and ocean acidification scenarios. We report that the physiological stresses associated with incubation without food over a 5-day period greatly exceed those caused directly by seawater temperature or pH perturbations. This highlights the need to contextualise the results of climate change experiments by comparison to other, naturally occurring stressors such as food deprivation, which is being exacerbated by global warming. Protein and lipid metabolism were up-regulated in the food-deprived animals, with a novel class of taurine-containing lipids and the essential polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid and docosahexaenoic acid, changing significantly over the duration of our experiment. Copepods derive these PUFAs by ingesting diatoms and flagellated microplankton respectively. Climate-driven changes in the productivity, phenology and composition of microplankton communities, and hence the availability of these fatty acids, therefore have the potential to influence the ability of copepods to survive starvation and other environmental stressors.

Peripheral Neuropathy and Nerve Compression Syndromes in Burns.

PubMed

Strong, Amy L; Agarwal, Shailesh; Cederna, Paul S; Levi, Benjamin

2017-10-01

Peripheral neuropathy and nerve compression syndromes lead to substantial morbidity following burn injury. Patients present with pain, paresthesias, or weakness along a specific nerve distribution or experience generalized peripheral neuropathy. The symptoms manifest at various times from within one week of hospitalization to many months after wound closure. Peripheral neuropathy may be caused by vascular occlusion of vasa nervorum, inflammation, neurotoxin production leading to apoptosis, and direct destruction of nerves from the burn injury. This article discusses the natural history, diagnosis, current treatments, and future directions for potential interventions for peripheral neuropathy and nerve compression syndromes related to burn injury. Copyright © 2017 Elsevier Inc. All rights reserved.

Cold plasma processing of local planetary ores for oxygen and metallurgically important metals

NASA Technical Reports Server (NTRS)

Lynch, D. C.; Bullard, D.; Ortega, R.

1990-01-01

The utilization of a cold plasma in chlorination processing is described. Essential equipment and instruments were received, the experimental apparatus assembled and tested, and preliminary experiments conducted. The results of the latter lend support to the original hypothesis: a cold plasma can both significantly enhance and bias chemical reactions. In two separate experiments, a cold plasma was used to reduce TiCl4 vapor and chlorinate ilmenite. The latter, reacted in an argon-chlorine plasma, yielded oxygen. The former experiment reveals that chlorine can be recovered as HCl vapor from metal chlorides in a hydrogen plasma. Furthermore, the success of the hydrogen experiments has lead to an analysis of the feasibility of direct hydrogen reduction of metal oxides in a cold plasma. That process would produce water vapor and numerous metal by-products.

Helicon Plasma Injector and Ion Cyclotron Acceleration Development in the VASIMR Experiment

NASA Technical Reports Server (NTRS)

Squire, Jared P.; Chang, Franklin R.; Jacobson, Verlin T.; McCaskill, Greg E.; Bengtson, Roger D.; Goulding, Richard H.

2000-01-01

In the Variable Specific Impulse Magnetoplasma Rocket (VASIMR) radio frequency (rf) waves both produce the plasma and then accelerate the ions. The plasma production is done by action of helicon waves. These waves are circular polarized waves in the direction of the electron gyromotion. The ion acceleration is performed by ion cyclotron resonant frequency (ICRF) acceleration. The Advanced Space Propulsion Laboratory (ASPL) is actively developing efficient helicon plasma production and ICRF acceleration. The VASIMR experimental device at the ASPL is called VX-10. It is configured to demonstrate the plasma production and acceleration at the 10kW level to support a space flight demonstration design. The VX-10 consists of three electromagnets integrated into a vacuum chamber that produce magnetic fields up to 0.5 Tesla. Magnetic field shaping is achieved by independent magnet current control and placement of the magnets. We have generated both helium and hydrogen high density (>10(exp 18) cu m) discharges with the helicon source. ICRF experiments are underway. This paper describes the VX-10 device, presents recent results and discusses future plans.

L-Asparaginase from Streptomyces griseus NIOT-VKMA29: optimization of process variables using factorial designs and molecular characterization of L-asparaginase gene

NASA Astrophysics Data System (ADS)

Meena, Balakrishnan; Anburajan, Lawrance; Sathish, Thadikamala; Vijaya Raghavan, Rangamaran; Dharani, Gopal; Valsalan Vinithkumar, Nambali; Kirubagaran, Ramalingam

2015-07-01

Marine actinobacteria are known to be a rich source for novel metabolites with diverse biological activities. In this study, a potential extracellular L-asparaginase was characterised from the Streptomyces griseus NIOT-VKMA29. Box-Behnken based optimization was used to determine the culture medium components to enhance the L-asparaginase production. pH, starch, yeast extract and L-asparagine has a direct correlation for enzyme production with a maximum yield of 56.78 IU mL-1. A verification experiment was performed to validate the experiment and more than 99% validity was established. L-Asparaginase biosynthesis gene (ansA) from Streptomyces griseus NIOT-VKMA29 was heterologously expressed in Escherichia coli M15 and the enzyme production was increased threefold (123 IU mL-1) over the native strain. The ansA gene sequences reported in this study encloses several base substitutions with that of reported sequences in GenBank, resulting in altered amino acid sequences of the translated protein.

The d-Prime directive: Assessing costs and benefits in recognition by dissociating mixed-list false alarm rates.

PubMed

Forrin, Noah D; Groot, Brianna; MacLeod, Colin M

2016-07-01

It can be difficult to judge the effectiveness of encoding techniques in a within-subject design. Consider the production effect-the finding that words read aloud are better remembered than words read silently. In the absence of a baseline, a within-subject production effect in a mixed study list could reflect a benefit of reading aloud, a cost of reading silently, or both. To help interpret within-subject data, memory researchers have compared within-subject and between-subjects designs, with the between-subjects (i.e., pure list) conditions serving as baselines against which the within-subject (i.e., mixed-list) conditions are compared. In the present article, the authors highlight a shortcoming of using this comparison to assess costs and benefits in recognition. Unlike between-subjects experiments where separate false alarm rates are obtained for each condition, the typical within-subject experiment yields a collapsed false alarm rate, which, the authors argue, can potentially bias calculations of memory discrimination (d'). Across 3 experiments that used production as the encoding manipulation, they used a typical mixed-list versus pure-list design (Experiment 1) and then made modifications to this design (Experiments 2 and 3) that yielded separate mixed-list false alarm rates. The results of the latter 2 experiments demonstrated that words that are read aloud in a mixed list have an overall memorial benefit over words that are read aloud in a pure list-both in terms of increased hits and reduced false alarms. The authors frame these results in terms of the distinctiveness heuristic. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Bidirectional associations in multiplication memory: conditions of negative and positive transfer.

PubMed

Campbell, Jamie I D; Robert, Nicole D

2008-05-01

A variety of experimental evidence indicates that the memory representation for multiplication facts (e.g., 6 x 9 = 54) incorporates bidirectional links with a forward association from factors to product and a reverse association from product to factors. Surprisingly, the authors did not find evidence in Experiment 1 of facilitative transfer-of-practice from multiplication (6 x 9 = ?) to factoring (54 = ? x ?); in fact, multiplication practice produced item-specific interference with factoring. Similarly, the authors found no evidence in Experiment 2 that repetition of specific factoring problems (54 = ? x ?) facilitated performance of corresponding multiplication problems (6 x 9 = ?). In Experiment 3, participants practiced both multiplication and factoring and presented facilitative transfer in both directions. Thus, bidirectional facilitation occurred if both operations were practiced, but interference occurred when only one operation was practiced. We propose that this seemingly paradoxical behavior occurs because it is adaptive for the bidirectional retrieval structure to retain operational flexibility in the context of practicing both operations, whereas it is adaptive to specialize the memory representation for the practiced operation (i.e., factoring or multiplication) when only one operation is practiced.

Contribution and pathways of diazotroph-derived nitrogen to zooplankton during the VAHINE mesocosm experiment in the oligotrophic New Caledonia lagoon

NASA Astrophysics Data System (ADS)

Hunt, Brian P. V.; Bonnet, Sophie; Berthelot, Hugo; Conroy, Brandon J.; Foster, Rachel A.; Pagano, Marc

2016-05-01

In oligotrophic tropical and subtropical oceans, where strong stratification can limit the replenishment of surface nitrate, dinitrogen (N2) fixation by diazotrophs can represent a significant source of nitrogen (N) for primary production. The VAHINE (VAriability of vertical and tropHIc transfer of fixed N2 in the south-wEst Pacific) experiment was designed to examine the fate of diazotroph-derived nitrogen (DDN) in such ecosystems. In austral summer 2013, three large ( ˜ 50 m3) in situ mesocosms were deployed for 23 days in the New Caledonia lagoon, an ecosystem that typifies the low-nutrient, low-chlorophyll environment, to stimulate diazotroph production. The zooplankton component of the study aimed to measure the incorporation of DDN into zooplankton biomass, and assess the role of direct diazotroph grazing by zooplankton as a DDN uptake pathway. Inside the mesocosms, the diatom-diazotroph association (DDA) het-1 predominated during days 5-15 while the unicellular diazotrophic cyanobacteria UCYN-C predominated during days 15-23. A Trichodesmium bloom was observed in the lagoon (outside the mesocosms) towards the end of the experiment. The zooplankton community was dominated by copepods (63 % of total abundance) for the duration of the experiment. Using two-source N isotope mixing models we estimated a mean ˜ 28 % contribution of DDN to zooplankton nitrogen biomass at the start of the experiment, indicating that the natural summer peak of N2 fixation in the lagoon was already contributing significantly to the zooplankton. Stimulation of N2 fixation in the mesocosms corresponded with a generally low-level enhancement of DDN contribution to zooplankton nitrogen biomass, but with a peak of ˜ 73 % in mesocosm 1 following the UCYN-C bloom. qPCR analysis targeting four of the common diazotroph groups present in the mesocosms (Trichodesmium, het-1, het-2, UCYN-C) demonstrated that all four were ingested by copepod grazers, and that their abundance in copepod stomachs generally corresponded with their in situ abundance. 15N2 labelled grazing experiments therefore provided evidence for direct ingestion and assimilation of UCYN-C-derived N by the zooplankton, but not for het-1 and Trichodesmium, supporting an important role of secondary pathways of DDN to the zooplankton for the latter groups, i.e. DDN contributions to the dissolved N pool and uptake by nondiazotrophs. This study appears to provide the first evidence of direct UCYN-C grazing by zooplankton, and indicates that UCYN-C-derived N contributes significantly to the zooplankton food web in the New Caledonia lagoon through a combination of direct grazing and secondary pathways.

Directional fidelity of nanoscale motors and particles is limited by the 2nd law of thermodynamics—Via a universal equality

NASA Astrophysics Data System (ADS)

Wang, Zhisong; Hou, Ruizheng; Efremov, Artem

2013-07-01

Directional motion of nanoscale motors and driven particles in an isothermal environment costs a finite amount of energy despite zero work as decreed by the 2nd law, but quantifying this general limit remains difficult. Here we derive a universal equality linking directional fidelity of an arbitrary nanoscale object to the least possible energy driving it. The fidelity-energy equality depends on the environmental temperature alone; any lower energy would violate the 2nd law in a thought experiment. Real experimental proof for the equality comes from force-induced motion of biological nanomotors by three independent groups - for translational as well as rotational motion. Interestingly, the natural self-propelled motion of a biological nanomotor (F1-ATPase) known to have nearly 100% energy efficiency evidently pays the 2nd law decreed least energy cost for direction production.

Contribution of direct electron transfer mechanisms to overall electron transfer in microbial fuel cells utilising Shewanella oneidensis as biocatalyst.

PubMed

Fapetu, Segun; Keshavarz, Taj; Clements, Mark; Kyazze, Godfrey

2016-09-01

To investigate the contribution of direct electron transfer mechanisms to electricity production in microbial fuel cells by physically retaining Shewanella oneidensis cells close to or away from the anode electrode. A maximum power output of 114 ± 6 mWm(-2) was obtained when cells were retained close to the anode using a dialysis membrane. This was 3.5 times more than when the cells were separated away from the anode. Without the membrane the maximum power output was 129 ± 6 mWm(-2). The direct mechanisms of electron transfer contributed significantly to overall electron transfer from S. oneidensis to electrodes, a result that was corroborated by another experiment where S. oneidensis cells were entrapped in alginate gels. S. oneidensis transfers electrons primarily by direct electron transfer as opposed to mediated electron transfer.

Measurements of reactive nitrogen produced by tropical thunderstorms during BIBLE-C

NASA Astrophysics Data System (ADS)

Koike, M.; Kondo, Y.; Kita, K.; Takegawa, N.; Nishi, N.; Kashihara, T.; Kawakami, S.; Kudoh, S.; Blake, D.; Shirai, T.; Liley, B.; Ko, M.; Miyazaki, Y.; Kawasaki, Z.; Ogawa, T.

2007-09-01

The Biomass Burning and Lightning Experiment phase C (BIBLE-C) aircraft mission was carried out near Darwin, Australia (12°S, 131°E) in December 2000. This was the first aircraft experiment designed to estimate lightning NO production rates in the tropics, where production is considered to be most intense. During the two flights (flights 10 and 13 made on December 9 and 11-12, respectively) enhancements of NOx (NO + NO2) up to 1000 and 1600 parts per trillion by volume (pptv, 10-s data) were observed at altitudes between 11.5 and 14 km. The Geostationary Meteorological Satellite (GMS) cloud (brightness temperature) data and ground-based lightning measurements by the Global Positioning and Tracking System (GPATS) indicate that there were intensive lightning events over the coast of the Gulf of Carpentaria, which took place upstream from our measurement area 10 to 14 h prior to the measurements. For these two flights, air in which NOx exceeded 100 pptv extended over 620 × 140 and 400 × 170 km2 (wind direction × perpendicular direction), respectively, suggesting a significant impact of lightning NO production on NOx levels in the tropics. We estimate the amount of NOx observed between 11.5 and 14 km produced by the thunderstorms to be 3.3 and 1.8 × 1029 NO molecules for flights 10 and 13, respectively. By using the GPATS lightning flash count data, column NO production rates are estimated to be 1.9-4.4 and 21-49 × 1025 NO molecules per single flash for these two flight data sets. In these estimations, it is assumed that the column NO production between 0 and 16 km is greater than the observed values between 11.5 and 14 km by a factor of 3.2, which is derived using results reported by Pickering et al. (1998). There are however large uncertainties in the GPATS lightning data in this study and care must be made when the production rates are referred. Uncertainties in these estimates are discussed. The impact on the ozone production rate is also described.

Analysis of turbulent transport and mixing in transitional Rayleigh–Taylor unstable flow using direct numerical simulation data

DOE PAGES

Schilling, Oleg; Mueschke, Nicholas J.

2010-10-18

Data from a 1152X760X1280 direct numerical simulation (DNS) of a transitional Rayleigh-Taylor mixing layer modeled after a small Atwood number water channel experiment is used to comprehensively investigate the structure of mean and turbulent transport and mixing. The simulation had physical parameters and initial conditions approximating those in the experiment. The budgets of the mean vertical momentum, heavy-fluid mass fraction, turbulent kinetic energy, turbulent kinetic energy dissipation rate, heavy-fluid mass fraction variance, and heavy-fluid mass fraction variance dissipation rate equations are constructed using Reynolds averaging applied to the DNS data. The relative importance of mean and turbulent production, turbulent dissipationmore » and destruction, and turbulent transport are investigated as a function of Reynolds number and across the mixing layer to provide insight into the flow dynamics not presently available from experiments. The analysis of the budgets supports the assumption for small Atwood number, Rayleigh/Taylor driven flows that the principal transport mechanisms are buoyancy production, turbulent production, turbulent dissipation, and turbulent diffusion (shear and mean field production are negligible). As the Reynolds number increases, the turbulent production in the turbulent kinetic energy dissipation rate equation becomes the dominant production term, while the buoyancy production plateaus. Distinctions between momentum and scalar transport are also noted, where the turbulent kinetic energy and its dissipation rate both grow in time and are peaked near the center plane of the mixing layer, while the heavy-fluid mass fraction variance and its dissipation rate initially grow and then begin to decrease as mixing progresses and reduces density fluctuations. All terms in the transport equations generally grow or decay, with no qualitative change in their profile, except for the pressure flux contribution to the total turbulent kinetic energy flux, which changes sign early in time (a countergradient effect). The production-to-dissipation ratios corresponding to the turbulent kinetic energy and heavy-fluid mass fraction variance are large and vary strongly at small evolution times, decrease with time, and nearly asymptote as the flow enters a self-similar regime. The late-time turbulent kinetic energy production-to-dissipation ratio is larger than observed in shear-driven turbulent flows. The order of magnitude estimates of the terms in the transport equations are shown to be consistent with the DNS at late-time, and also confirms both the dominant terms and their evolutionary behavior. Thus, these results are useful for identifying the dynamically important terms requiring closure, and assessing the accuracy of the predictions of Reynolds-averaged Navier-Stokes and large-eddy simulation models of turbulent transport and mixing in transitional Rayleigh-Taylor instability-generated flow.« less

A search for heavy leptons at HERA

NASA Astrophysics Data System (ADS)

Ahmed, T.; Aid, S.; Andreev, V.; Andrieu, B.; Appuhn, R.-D.; Arpagaus, M.; Babaev, A.; Baehr, J.; Bán, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Barth, M.; Bassler, U.; Beck, H. P.; Behrend, H.-J.; Belousov, A.; Berger, Ch.; Bergstein, H.; Bernardi, G.; Bernet, R.; Bertrand-Coremans, G.; Besançon, M.; Biddulph, P.; Bizot, J. C.; Blobel, V.; Borras, K.; Botterweck, F.; Boudry, V.; Braemer, A.; Brasse, F.; Braunschweig, W.; Brisson, V.; Bruncko, D.; Brune, C.; Buchholz, R.; Büngener, L.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Buschhorn, G.; Campbell, A. J.; Carli, T.; Charles, F.; Clarke, D.; Clegg, A. B.; Colombo, M.; Contreras, J. G.; Coughlan, J. A.; Courau, A.; Coutures, Ch.; Cozzika, G.; Criegee, L.; Cussans, D. G.; Cvach, J.; Dagoret, S.; Dainton, J. B.; Danilov, M.; Dau, W. D.; Daum, K.; David, M.; Deffur, E.; Delcourt, B.; Del Buono, L.; De Roeck, A.; De Wolf, E. A.; Di Nezza, P.; Dollfus, C.; Dowell, J. D.; Dreis, H. B.; Duboc, J.; Düllmann, D.; Dünger, O.; Duhm, H.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Ehrlichmann, H.; Eichenberger, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellison, R. J.; Elsen, E.; Erdmann, M.; Evrard, E.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Ferencei, J.; Ferrarotto, F.; Flamm, K.; Fleischer, M.; Flieser, M.; Flügge, G.; Fomenko, A.; Fominykh, B.; Forbush, M.; Formánek, J.; Foster, J. M.; Franke, G.; Fretwurst, E.; Gabathuler, E.; Gabathuler, K.; Gamerdinger, K.; Garvey, J.; Gayler, J.; Gebauer, M.; Gellrich, A.; Genzel, H.; Gerhards, R.; Goerlach, U.; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goldner, D.; Gonzalez-Pineiro, B.; Goodall, A. M.; Gorelov, I.; Goritchev, P.; Grab, C.; Grässler, H.; Grässler, R.; Greenshaw, T.; Grindhammer, G.; Gruber, A.; Gruber, C.; Haack, J.; Haidt, D.; Hajduk, L.; Hamon, O.; Hampel, M.; Hanlon, E. M.; Hapke, M.; Haynes, W. J.; Heatherington, J.; Hedberg, V.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herma, R.; Herynek, I.; Hess, M. F.; Hildesheim, W.; Hill, P.; Hiller, K. H.; Hilton, C. D.; Hladký, J.; Hoeger, K. C.; Höppner, M.; Horisberger, R.; Huet, Ph.; Hufnagel, H.; Ibbotson, M.; Itterbeck, H.; Jabiol, M.-A.; Jacholkowska, A.; Jacobsson, C.; Jaffre, M.; Janoth, J.; Jansen, T.; Jönsson, L.; Johanssen, K.; Johnson, D. P.; Johnson, L.; Jung, H.; Kalmus, P. I. P.; Kant, D.; Kaschowitz, R.; Kasselmann, P.; Kathage, U.; Kaufmann, H. H.; Kazarian, S.; Kenyon, I. R.; Kermiche, S.; Keuker, C.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Ko, W.; Köhler, T.; Kolanoski, H.; Kole, F.; Kolya, S. D.; Korbel, V.; Korn, M.; Kostka, P.; Kotelnikov, S. K.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Krüger, U.; Krüner-Marquis, U.; Kubenka, J. P.; Küster, H.; Kuhlen, M.; Kurča, T.; Kurzhöfer, J.; Kuznik, B.; Lacour, D.; Lamarche, F.; Lander, R.; Landon, M. P. J.; Lange, W.; Lanius, P.; Laporte, J. F.; Lebedev, A.; Leverenz, C.; Levonian, S.; Ley, Ch.; Lindner, A.; Lindström, G.; Linsel, F.; Lipinski, J.; List, B.; Loch, P.; Lohmander, H.; Lopez, G. C.; Lüke, D.; Magnussen, N.; Malinovski, E.; Mani, S.; Maraček, R.; Marage, P.; Marshall, R.; Martens, J.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Masson, S.; Mavroidis, T.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Mercer, D.; Merz, T.; Meyer, C. A.; Meyer, H.; Meyer, J.; Mikocki, S.; Milstead, D.; Moreau, F.; Morris, J. V.; Müller, G.; Müller, K.; Murín, P.; Nagovizin, V.; Nahnhauer, R.; Naroska, B.; Naumann, Th.; Newman, P. R.; Newton, D.; Neyret, D.; Nguyen, H. K.; Niebergall, F.; Niebuhr, C.; Nisius, R.; Nowak, G.; Noyes, G. W.; Nyberg-Werther, M.; Oberlack, H.; Obrock, U.; Olsson, J. E.; Panitch, A.; Pascaud, C.; Patel, G. D.; Peppel, E.; Perez, E.; Phillips, J. P.; Pichler, Ch.; Pitzl, D.; Pope, G.; Prell, S.; Prosi, R.; Rädel, G.; Raupach, F.; Reimer, P.; Reinshagen, S.; Ribarics, P.; Riech, V.; Riedlberger, J.; Riess, S.; Rietz, M.; Robertson, S. M.; Robmann, P.; Roloff, H. E.; Roosen, R.; Rosenbauer, K.; Rostovtsev, A.; Rouse, F.; Royon, C.; Rüter, K.; Rusakov, S.; Rybicki, K.; Rylko, R.; Sahlmann, N.; Sanchez, E.; Sankey, D. P. C.; Savitsky, M.; Schacht, P.; Schiek, S.; Schleper, P.; von Schlippe, W.; Schmidt, C.; Schmidt, D.; Schmidt, G.; Schöning, A.; Schröder, V.; Schuhmann, E.; Schwab, B.; Schwind, A.; Seehausen, U.; Sefkow, F.; Seidel, M.; Sell, R.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shooshtari, H.; Shtarkov, L. N.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Smirnov, P.; Smith, J. R.; Soloviev, Y.; Spitzer, H.; Starosta, R.; Steenbock, M.; Steffen, P.; Steinberg, R.; Stella, B.; Stephens, K.; Stier, J.; Stiewe, J.; Stösslein, U.; Strachota, J.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Tapprogge, S.; Taylor, R. E.; Tchernyshov, V.; Thiebaux, C.; Thompson, G.; Tichomirov, I.; Truöl, P.; Turnau, J.; Tutas, J.; Uelkes, P.; Usik, A.; Valkár, S.; Valkárová, A.; Vallée, C.; Van Esch, P.; Van Mechelen, P.; Vartapetian, A.; Vazdik, Y.; Vecko, M.; Verrecchia, P.; Villet, G.; Wacker, K.; Wagener, A.; Walker, I. W.; Walther, A.; Weber, G.; Weber, M.; Wegener, D.; Wegener, A.; Wellisch, H. P.; West, L. R.; Willard, S.; Winde, M.; Winter, G.-G.; Wolff, Th.; Wright, A. E.; Wünsch, E.; Wulff, N.; Yiou, T. P.; Žáček, J.; Zhang, Z.; Zimmer, M.; Zimmermann, W.; Zomer, F.; Zuber, K.; H1 Collaboration

1994-12-01

A search for direct production of new leptons in the mass range from 10 GeV up to 225 GeV is presented by the H1 experiment at HERA. The data were obtained during 1993 and correspond to an integrated luminosity of 528 nb -1. The search includes heavy lepton decays to final states e ( ν) γ and e ( ν) W, e( ν) Z with the subsequent decay of the W and Z bosons into jets or lepton pairs. No evidence was found for the production of new massive electrons or neutrinos in any of the decay channels. Rejection limits for excited electrons and neutrinos are derived.

Mass Spectrometry in the Home and Garden

NASA Astrophysics Data System (ADS)

Pulliam, Christopher J.; Bain, Ryan M.; Wiley, Joshua S.; Ouyang, Zheng; Cooks, R. Graham

2015-02-01

Identification of active components in a variety of chemical products used directly by consumers is described at both trace and bulk levels using mass spectrometry. The combination of external ambient ionization with a portable mass spectrometer capable of tandem mass spectrometry provides high chemical specificity and sensitivity as well as allowing on-site monitoring. These experiments were done using a custom-built portable ion trap mass spectrometer in combination with the ambient ionization methods of paper spray, leaf spray, and low temperature plasma ionization. Bactericides, garden chemicals, air fresheners, and other products were examined. Herbicide applied to suburban lawns was detected in situ on single leaves 5 d after application.

Palladium-Mediated Catalysis Leads to Intramolecular Narcissistic Self-Sorting on a Cavitand Platform.

PubMed

Nagymihály, Zoltán; Caturello, Naidel A M S; Takátsy, Anikó; Aragay, Gemma; Kollár, László; Albuquerque, Rodrigo Q; Csók, Zsolt

2017-01-06

Palladium-catalyzed aminocarbonylation reactions have been used to directly convert a tetraiodocavitand intermediate into the corresponding carboxamides and 2-ketocarboxamides. When complex mixtures of the amine reactants are employed in competition experiments using polar solvents, such as DMF, no "mixed" products possessing structurally different amide fragments are detected either by 1 H or 13 C NMR. Only highly symmetrical cavitands are sorted out of a large number of potentially feasible products, which represents a rare example of intramolecular, narcissistic self-sorting. Our experimental results along with thermodynamic energy analysis suggest that the observed self-sorting is a symmetry-driven, kinetically controlled process.

Information sciences experiment system

NASA Technical Reports Server (NTRS)

Katzberg, Stephen J.; Murray, Nicholas D.; Benz, Harry F.; Bowker, David E.; Hendricks, Herbert D.

1990-01-01

The rapid expansion of remote sensing capability over the last two decades will take another major leap forward with the advent of the Earth Observing System (Eos). An approach is presented that will permit experiments and demonstrations in onboard information extraction. The approach is a non-intrusive, eavesdropping mode in which a small amount of spacecraft real estate is allocated to an onboard computation resource. How such an approach allows the evaluation of advanced technology in the space environment, advanced techniques in information extraction for both Earth science and information science studies, direct to user data products, and real-time response to events, all without affecting other on-board instrumentation is discussed.

Saccharification of Miscanthus x giganteus, incorporation of lignocellulosic by-product in cementitious matrix.

PubMed

Le Ngoc Huyen, Tran; Queneudec T'kint, Michèle; Remond, Caroline; Chabbert, Brigitte; Dheilly, Rose-Marie

2011-11-01

Given the non competition of miscanthus with food and animal feed, this lignocellulosic species has attracted attention as a possible biofuel resource. However, sustainability of ethanol production from lignocelluloses biomass would imply reduction in the consumption of chemicals and/or energetic means, but also valorization of the lignocellulosic by-product remaining from enzymatic saccharification. Introduction of these by-products into a cementitious matrix could be used in manufacturing a lightweight composite. Miscanthus biomass was submitted to chemical pretreatments followed by saccharification using an enzymatic cocktail. Residues from saccharification were then mixed with a cementitious matrix. Given their mechanical properties and a good adherence between cement and by-product, the hardened materials could be used. However, the delay in the beginning of setting time is too long, which prevents the direct use of by-product into cementitious matrix. Preliminary experiments using a setting accelerator in the cementitious matrix permitted significant reduction in the setting time delay. Copyright © 2011 Académie des sciences. Published by Elsevier SAS. All rights reserved.

Molecular variation of the nonribosomal peptide-polyketide siderophore yersiniabactin through biosynthetic and metabolic engineering.

PubMed

Ahmadi, Mahmoud Kamal; Fawaz, Samar; Fang, Lei; Yu, Zhipeng; Pfeifer, Blaine A

2016-05-01

The production of the mixed nonribosomal peptide-polyketide natural product yersiniabactin (Ybt) has been established using E. coli as a heterologous host. In this study, precursor-directed biosynthesis was used to generate five new analogs of Ybt, demonstrating the flexibility of the heterologous system and the biosynthetic process in allowing compound diversity. A combination of biosynthetic and cellular engineering was then used to influence the production metrics of the resulting analogs. First, the cellular levels and activity of FadL, a hydrocarbon transport protein, were tested for subsequent influence upon exogenous precursor uptake and Ybt analog production with a positive correlation observed between FadL over-production and analog formation. Next, a Ybt biosynthetic editing enzyme was removed from the heterologous system which decreased native compound production but increased analog formation. A final series of experiments enhanced endogenous anthranilate towards complete pathway formation of the associated analog which showed a selective ability to bind gold. © 2015 Wiley Periodicals, Inc.

Priming thoughts about extravagance: implications for consumer decisions about luxury products.

PubMed

Park, Jongwon; Kim, Kyeongheui; Kwak, Junsik; Wyer, Robert S

2014-03-01

If a semantic concept is accessible in memory, it can direct attention to the attributes of a target that exemplify this concept. When these attributes have both affective and utilitarian implications that are evaluatively opposite, the relative impact of these different implications depends on an individual's ability and motivation to expend the cognitive effort required to evaluate them. These assumptions were confirmed in six experiments on the impact of priming the concept of extravagance on attention to a product's luxury-related features and consequent reactions to it. Priming this concept decreased the choice of a luxury product if participants were both motivated and able to construe the utilitarian implications of the product's extravagance-related features. When participants were either distracted from deliberating on their choices or were asked to recommend a product to others, however, priming extravagance led them to base their judgments on the affective reactions that the features spontaneously elicited and consequently increased their choice of the product. © 2013 American Psychological Association

First observation of coherent π production in neutrino nucleus interactions with E<2 GeV

NASA Astrophysics Data System (ADS)

Miniboone Collaboration; Aguilar-Arevalo, A. A.; Anderson, C. E.; Bazarko, A. O.; Brice, S. J.; Brown, B. C.; Bugel, L.; Cao, J.; Coney, L.; Conrad, J. M.; Cox, D. C.; Curioni, A.; Djurcic, Z.; Finley, D. A.; Fleming, B. T.; Ford, R.; Garcia, F. G.; Garvey, G. T.; Green, C.; Green, J. A.; Hart, T. L.; Hawker, E.; Imlay, R.; Johnson, R. A.; Karagiori, G.; Kasper, P.; Katori, T.; Kobilarcik, T.; Kourbanis, I.; Koutsoliotas, S.; Laird, E. M.; Linden, S. K.; Link, J. M.; Liu, Y.; Liu, Y.; Louis, W. C.; Mahn, K. B. M.; Marsh, W.; Martin, P. S.; McGregor, G.; Metcalf, W.; Meyers, P. D.; Mills, F.; Mills, G. B.; Monroe, J.; Moore, C. D.; Nelson, R. H.; Nguyen, V. T.; Nienaber, P.; Nowak, J. A.; Ouedraogo, S.; Patterson, R. B.; Perevalov, D.; Polly, C. C.; Prebys, E.; Raaf, J. L.; Ray, H.; Roe, B. P.; Russell, A. D.; Sandberg, V.; Schirato, R.; Schmitz, D.; Shaevitz, M. H.; Shoemaker, F. C.; Smith, D.; Soderberg, M.; Sorel, M.; Spentzouris, P.; Stancu, I.; Stefanski, R. J.; Sung, M.; Tanaka, H. A.; Tayloe, R.; Tzanov, M.; van de Water, R.; Wascko, M. O.; White, D. H.; Wilking, M. J.; Yang, H. J.; Zeller, G. P.; Zimmerman, E. D.

2008-06-01

The MiniBooNE experiment at Fermilab has amassed the largest sample to date of πs produced in neutral current (NC) neutrino nucleus interactions at low energy. This Letter reports a measurement of the momentum distribution of πs produced in mineral oil (CH2) and the first observation of coherent π production below 2 GeV. In the forward direction, the yield of events observed above the expectation for resonant production is attributed primarily to coherent production off carbon, but may also include a small contribution from diffractive production on hydrogen. Integrated over the MiniBooNE neutrino flux, the sum of the NC coherent and diffractive modes is found to be (19.5±1.1(stat)±2.5(sys))% of all exclusive NC π production at MiniBooNE. These measurements are of immediate utility because they quantify an important background to MiniBooNE's search for ν→ν oscillations.

First observation of coherent π0 production in neutrino-nucleus interactions with Eν < 2 GeV

NASA Astrophysics Data System (ADS)

Aguilar-Arevalo, A. A.; Anderson, C. E.; Bazarko, A. O.; Brice, S. J.; Brown, B. C.; Bugel, L.; Cao, J.; Coney, L.; Conrad, J. M.; Cox, D. C.; Curioni, A.; Djurcic, Z.; Finley, D. A.; Fleming, B. T.; Ford, R.; Garcia, F. G.; Garvey, G. T.; Green, C.; Green, J. A.; Hart, T. L.; Hawker, E.; Imlay, R.; Johnson, R. A.; Karagiori, G.; Kasper, P.; Katori, T.; Kobilarcik, T.; Kourbanis, I.; Koutsoliotas, S.; Laird, E. M.; Linden, S. K.; Link, J. M.; Liu, Y.; Liu, Y.; Louis, W. C.; Mahn, K. B. M.; Marsh, W.; Martin, P. S.; McGregor, G.; Metcalf, W.; Meyers, P. D.; Mills, F.; Mills, G. B.; Monroe, J.; Moore, C. D.; Nelson, R. H.; Nguyen, V. T.; Nienaber, P.; Nowak, J. A.; Ouedraogo, S.; Patterson, R. B.; Perevalov, D.; Polly, C. C.; Prebys, E.; Raaf, J. L.; Ray, H.; Roe, B. P.; Russell, A. D.; Sandberg, V.; Schirato, R.; Schmitz, D.; Shaevitz, M. H.; Shoemaker, F. C.; Smith, D.; Soderberg, M.; Sorel, M.; Spentzouris, P.; Stancu, I.; Stefanski, R. J.; Sung, M.; Tanaka, H. A.; Tayloe, R.; Tzanov, M.; Van de Water, R.; Wascko, M. O.; White, D. H.; Wilking, M. J.; Yang, H. J.; Zeller, G. P.; Zimmerman, E. D.; MiniBooNE Collaboration

2008-06-01

The MiniBooNE experiment at Fermilab has amassed the largest sample to date of π0s produced in neutral current (NC) neutrino-nucleus interactions at low energy. This Letter reports a measurement of the momentum distribution of π0s produced in mineral oil (CH2) and the first observation of coherent π0 production below 2 GeV. In the forward direction, the yield of events observed above the expectation for resonant production is attributed primarily to coherent production off carbon, but may also include a small contribution from diffractive production on hydrogen. Integrated over the MiniBooNE neutrino flux, the sum of the NC coherent and diffractive modes is found to be (19.5 ± 1.1 (stat) ± 2.5 (sys)) % of all exclusive NC π0 production at MiniBooNE. These measurements are of immediate utility because they quantify an important background to MiniBooNE's search for νμ →νe oscillations.

Touch displays: the effects of palm rejection technology on productivity, comfort, biomechanics and positioning.

PubMed

Camilleri, Matt J; Malige, Ajith; Fujimoto, Jeffrey; Rempel, David M

2013-01-01

Direct touch displays can improve the human-computer experience and productivity; however, the higher hand locations may increase shoulder fatigue. Palm rejection (PR) technology may reduce shoulder loads by allowing the palms to rest on the display and increase productivity by registering the touched content and fingertips through the palms rather than shoulders. The effects of PR were evaluated by having participants perform touch tasks while posture and reaction force on the display were measured. Enabling PR, during which the subjects could place the palms on the display (but were not required to), resulted in increased wrist extension, force applied to the display and productivity, and less discomfort, but had no effect on the self-selected positioning of the display. Participants did not deliberately place their palms on the display; therefore, there was no reduction in shoulder load and the increased productivity was not due to improved hand registration. The increased productivity may have been due to reduced interruptions from palm contacts or reduced motor control demands.

Benchmark experiment for the cross section of the 100Mo(p,2n)99mTc and 100Mo(p,pn)99Mo reactions

NASA Astrophysics Data System (ADS)

Takács, S.; Ditrói, F.; Aikawa, M.; Haba, H.; Otuka, N.

2016-05-01

As nuclear medicine community has shown an increasing interest in accelerator produced 99mTc radionuclide, the possible alternative direct production routes for producing 99mTc were investigated intensively. One of these accelerator production routes is based on the 100Mo(p,2n)99mTc reaction. The cross section of this nuclear reaction was studied by several laboratories earlier but the available data-sets are not in good agreement. For large scale accelerator production of 99mTc based on the 100Mo(p,2n)99mTc reaction, a well-defined excitation function is required to optimise the production process effectively. One of our recent publications pointed out that most of the available experimental excitation functions for the 100Mo(p,2n)99mTc reaction have the same general shape while their amplitudes are different. To confirm the proper amplitude of the excitation function, results of three independent experiments were presented (Takács et al., 2015). In this work we present results of a thick target count rate measurement of the Eγ = 140.5 keV gamma-line from molybdenum irradiated by Ep = 17.9 MeV proton beam, as an integral benchmark experiment, to prove the cross section data reported for the 100Mo(p,2n)99mTc and 100Mo(p,pn)99Mo reactions in Takács et al. (2015).

Understanding Fluid Shifts in the Brain: Choroidal Regulation Involved in the Cerebral Fluid Response to Altered Gravity

NASA Technical Reports Server (NTRS)

Gabrion, Jaqueline; Vasques, Marilyn; Aquilina, Rudy (Technical Monitor)

2002-01-01

Fluid balance and regulation of body fluid production are critical aspects of life and survival on Earth. In space, without gravity exerting its usual downward pulling effect, the fluids of the human body shift in an unnatural, headward direction. After awhile, humans and other mammalian species adapt to the microgravity environment which leads to changes in the regulation and distribution of these body fluids. Previous spaceflight experiments have indicated that production of fluid in the brain and spinal cord, cerebrospinal fluid (CSF), might be reduced in rats exposed to microgravity. In this experiment conducted by Dr. Jacqueline Gabrion (University of Pierre and Marie Curie, France), proteins important for CSF production, and several molecules that regulate water and mineral transport, will be investigated in rats flown on the Shuttle. Dr. Gabrion and her team will determine the amounts of these proteins and molecules present in the brain in order to evaluate whether any changes have taken place during the rats' adaptation to microgravity. The levels of different aquaporins (proteins that act as a channel for water transport in and out of cells) will also be investigated in other areas of the brain and body to better understand the regulatory responses affecting these important water channel proteins. In addition to producing essential and basic information about fluid production in the brain and body, this experiment will reveal fundamental information about the mechanisms involved in cerebral adaptation and fluid balance during spaceflight.

[The production of optical glass in France and the experiences of Ruggiero Boscovich for the production of lead glass (Part One)].

PubMed

Proverbio, Edoardo

The experiences that in 1758 led John Dollond to create the first achromatic telescope highlighted the serious difficulties related to the production of lenses with a correction for chromatic aberration. These difficulties were due to the lack of suitable tools for measuring the refraction index and for verifying the curvatures of the lenses of such optical instruments. To this was added what was perhaps the greatest difficulty: i.e., that of acquiring the kinds of glass, the so-called "common" (crown) glass and "lead" (flint) glass, of which the lenses had to be made. If the theoretical works of Alexis Clairaut, of Samuel Klingenstierna, and of Ruggiero Boscovich furnished the theoretical basis for producing such lenses, and subsequently--after Boscovich's discovery of the role of the eyepieces--for creating also achromatic eyepieces, the greatest challenge from the practical point of view was that of the availability of the flint glass. In this first part of the article there is then a study of the numerous attempts and directions pursued by Clairaut and his valid collaborators--Anthéaulme, George father and son, Charles François de l'Etang, and Claude Siméon Passemant--in order to find common glass and lead glass, and to produce the first achromatic lenses and binoculars in France. An analysis follows of the experiences conducted by Boscovich, first in Vienna, and then in Milan and Venice-Murano, addressed to the production of flint glass.

Deposition and spatial variation of thoron decay products in a thoron experimental house using the Direct Thoron Progeny Sensors.

PubMed

Mishra, R; Joshi, M; Meisenberg, O; Gierl, S; Prajith, R; Kanse, S D; Rout, R; Sapra, B K; Mayya, Y S; Tschiersch, J

2017-06-26

Experiments have been carried out using the deposition-based Direct Thoron Progeny Sensors (DTPS) in a thoron experimental house. The objective was to study the thoron decay product characteristics such as the deposition velocities, spatial variability and dependence on aerosol particle concentrations. Since the deposition velocity is an important characteristic in the calibration of the DTPS, it is very important to study its dependence on aerosol concentration in a controlled environment. At low aerosol concentration (1500 particles/cm 3 ) the mean effective deposition velocity was measured to be 0.159 ± 0.045 m h -1 ; at high aerosol concentration (30 000 particles/cm 3 ) it decreased to 0.079 ± 0.009 m h -1 . The deposition velocity for the attached fraction of the thoron decay products did not change with increasing aerosol concentration, showing measurement results of 0.048 ± 0.005 m h -1 and 0.043 ± 0.014 m h -1 , respectively. At low particle concentration, the effective deposition velocity showed large scattering within the room at different distances from center. The attached fraction deposition velocity remained uniform at different distances from the wall. The measurements in the thoron experimental house can be used as a sensitivity test of the DTPS in an indoor environment with changing aerosol concentration. The uniform spatial distribution of thoron decay products was confirmed within the experimental house. This indicates that direct measurement of thoron decay product concentration should be carried out instead of inferring it from thoron gas concentration, which is very inhomogeneous within the experimental house.

Nanobiocatalytic Degradation of Acid Orange 7

NASA Astrophysics Data System (ADS)

Hastings, Jason

The catalytic properties of various metal nanoparticles have led to their use in environmental remediation applications. However, these remediation strategies are limited by their ability to deliver catalytic nanoparticles and a suitable electron donor to large treatment zones. Clostridium pasteurianum BC1 cells, loaded with bio-Pd nanoparticles, were used to effectively catalyze the reductive degradation and removal of Acid Orange 7 (AO7), a model azo compound. Hydrogen produced fermentatively by the C. pasteurianum BC1 acted as the electron donor for the process. Pd-free bacterial cultures or control experiments conducted with heat-killed cells showed limited reduction of AO7. Experiments also showed that the in situ biological production of H2 by C. pasteurianum BC1 was essential for the degradation of AO7, which suggests a novel process where the in situ microbial production of hydrogen is directly coupled to the catalytic bio-Pd mediated reduction of AO7. The differences in initial degradation rate for experiments conducted using catalyst concentrations of 1ppm Pd and 5ppm Pd and an azo dye concentration of 100ppm AO7 was 0.39 /hr and 1.94 /hr respectively, demonstrating the importance of higher concentrations of active Pd(0). The degradation of AO7 was quick as demonstrated by complete reductive degradation of 50ppm AO7 in 2 hours in experiments conducted using a catalyst concentration of 5ppm Pd. Dye degradation products were analyzed via Gas Chromatograph-Mass Spectrometer (GCMS), High Performance Liquid Chromatography (HPLC), UltraViolet-Visible spectrophotometer (UV-Vis) and Matrix-Assisted Laser Desorption/Ionization (MALDI) spectrometry. The presence of 1-amino 2-naphthol, one of the hypothesized degradation products, was confirmed using mass spectrometry.

Highly efficient direct Z-scheme WO3/CdS-diethylenetriamine photocatalyst and its enhanced photocatalytic H2 evolution under visible light irradiation

NASA Astrophysics Data System (ADS)

Hu, Taiping; Li, Pengfei; Zhang, Jinfeng; Liang, Changhao; Dai, Kai

2018-06-01

Cadmium sulfide (CdS) has demonstrated great promise in artificial photocataytic hydrogen (H2) production. However, the serious photocorrosion hinders its effective interaction and real-life application. In this work, a typical direct Z-scheme WO3/CdS-diethylenetriamine (CdS-DETA) composite has been designed via facile in-situ solvothermal method, which exhibits excellent H2 production properties in visible light region. In this system, the inorganic-organic CdS-DETA nanobelts (NBs) possess enough active sites and large surface area for the encouraging nanojunction structure information. Furthermore, we also systematically calculated energy band structure and investigated charge transfer of the WO3/CdS-DETA by PL and photocurrent test, the results demonstrated that the suitable band gap matching between CdS-DETA and WO3 and high redox potential improve the separation of photogenerated holes and electrons, restraining intrinsic photocorrosion of CdS as well as improving the photocatalytic activity. 5%WO3/CdS-DETA presented the most outstanding H2 evolution rate (15522 μmol g-1 h-1), which is twice higher than that of pure CdS-DETA. WO3/CdS-DETA composites also presented high stability after three recycle H2 production experiment. Finally, direct Z-scheme photocatalytic mechanism is calculated.

Current Concepts in Tissue Engineering: Skin and Wound.

PubMed

Tenenhaus, Mayer; Rennekampff, Hans-Oliver

2016-09-01

Pure regenerative healing with little to no donor morbidity remains an elusive goal for both surgeon and patient. The ability to engineer and promote the development of like tissue holds so much promise, and efforts in this direction are slowly but steadily advancing. Products selected and reviewed reflect historical precedence and importance and focus on current clinically available products in use. Emerging technologies we anticipate will further expand our therapeutic options are introduced. The topic of tissue engineering is incredibly broad in scope, and as such the authors have focused their review on that of constructs specifically designed for skin and wound healing. A review of pertinent and current clinically related literature is included. Products such as biosynthetics, biologics, cellular promoting factors, and commercially available matrices can be routinely found in most modern health care centers. Although to date no complete regenerative or direct identical soft-tissue replacement exists, currently available commercial components have proven beneficial in augmenting and improving some types of wound healing scenarios. Cost, directed specificity, biocompatibility, and bioburden tolerance are just some of the impending challenges to adoption. Quality of life and in fact the ability to sustain life is dependent on our most complex and remarkable organ, skin. Although pure regenerative healing and engineered soft-tissue constructs elude us, surgeons and health care providers are slowly gaining comfort and experience with concepts and strategies to improve the healing of wounds.

Studies of Positron Generation from Ultraintense Laser-Matter Interactions

NASA Astrophysics Data System (ADS)

Williams, Gerald Jackson

Laser-produced pair jets possess unique characteristics that offer great potential for their use in laboratory-astrophysics experiments to study energetic phenomenon such as relativistic shock accelerations. High-flux, high-energy positron sources may also be used to study relativistic pair plasmas and useful as novel diagnostic tools for high energy density conditions. Copious amounts of positrons are produced with MeV energies from directly irradiating targets with ultraintense lasers where relativistic electrons, accelerated by the laser field, drive positron-electron pair production. Alternatively, laser wakefield accelerated electrons can produce pairs by the same mechanisms inside a secondary converter target. This dissertation describes a series of novel experiments that investigate the characteristics and scaling of pair production from ultraintense lasers, which are designed to establish a robust platform for laboratory-based relativistic pair plasmas. Results include a simple power-law scaling to estimate the effective positron yield for elemental targets for any Maxwellian electron source, typical of direct laser-target interactions. To facilitate these measurements, a solenoid electromagnetic coil was constructed to focus emitted particles, increasing the effective collection angle of the detector and enabling the investigation of pair production from thin targets and low-Z materials. Laser wakefield electron sources were also explored as a compact, high repetition rate platform for the production of high energy pairs with potential applications to the creation of charge-neutral relativistic pair plasmas. Plasma accelerators can produce low-divergence electron beams with energies approaching a GeV at Hz frequencies. It was found that, even for high-energy positrons, energy loss and scattering mechanisms in the target create a fundamental limit to the divergence and energy spectrum of the emitted positrons. The potential future application of laser-generated pairs was considered by exploring the feasibility of radiographing an imploding inertial confinement fusion capsule at ignition- relevant conditions. For an in-flight areal density of 0.02-0.2 g/cm2, currently available positron sources can make density and spatial measurements of deuterium-tritium fuel cores where additional complications of full-scale experiments are expected to reduce the measurement sensitivity.

Chemical dynamics simulations of the monohydrated OH{sup −}(H{sub 2}O) + CH{sub 3}I reaction. Atomic-level mechanisms and comparison with experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, Jing; Hase, William L., E-mail: bill.hase@ttu.edu; Otto, Rico

2015-06-28

Direct dynamics simulations, with B97-1/ECP/d theory, were performed to study the role of microsolvation for the OH{sup −}(H{sub 2}O) + CH{sub 3}I reaction. The S{sub N}2 reaction dominates at all reactant collision energies, but at higher collision energies proton transfer to form CH{sub 2}I{sup −}, and to a lesser extent CH{sub 2}I{sup −} (H{sub 2}O), becomes important. The S{sub N}2 reaction occurs by direct rebound and stripping mechanisms, and 28 different indirect atomistic mechanisms, with the latter dominating. Important components of the indirect mechanisms are the roundabout and formation of S{sub N}2 and proton transfer pre-reaction complexes and intermediates, includingmore » [CH{sub 3}--I--OH]{sup −}. In contrast, for the unsolvated OH{sup −} + CH{sub 3}I S{sub N}2 reaction, there are only seven indirect atomistic mechanisms and the direct mechanisms dominate. Overall, the simulation results for the OH{sup −}(H{sub 2}O) + CH{sub 3}I S{sub N}2 reaction are in good agreement with experiment with respect to reaction rate constant, product branching ratio, etc. Differences between simulation and experiment are present for the S{sub N}2 velocity scattering angle at high collision energies and the proton transfer probability at low collision energies. Equilibrium solvation by the H{sub 2}O molecule is unimportant. The S{sub N}2 reaction is dominated by events in which H{sub 2}O leaves the reactive system as CH{sub 3}OH is formed or before CH{sub 3}OH formation. Formation of solvated products is unimportant and participation of the (H{sub 2}O)CH{sub 3}OH---I{sup −} post-reaction complex for the S{sub N}2 reaction is negligible.« less

Excitation of Mercuric Bromide by Electrons.

DTIC Science & Technology

1982-08-30

molecular beam of IHgBr 2 . The apparatus permits simultaneous meas- urements of negative ion, positive ion, and wavelength resolved photon production...system has proven to be trouble-free and allows very close control of the IHgBr 2, vapor pressure and conseqt’ent molecular beam intensity. The...experiment is represented schematicallv in Figure 1. The gas under study is introduced into the collision region in the form of a molecular beam, directed

Metabolic engineering of the L-phenylalanine pathway in Escherichia coli for the production of S- or R-mandelic acid

PubMed Central

2011-01-01

Background Mandelic acid (MA), an important component in pharmaceutical syntheses, is currently produced exclusively via petrochemical processes. Growing concerns over the environment and fossil energy costs have inspired a quest to develop alternative routes to MA using renewable resources. Herein we report the first direct route to optically pure MA from glucose via genetic modification of the L-phenylalanine pathway in E. coli. Results The introduction of hydroxymandelate synthase (HmaS) from Amycolatopsis orientalis into E. coli led to a yield of 0.092 g/L S-MA. By combined deletion of competing pathways, further optimization of S-MA production was achieved, and the yield reached 0.74 g/L within 24 h. To produce R-MA, hydroxymandelate oxidase (Hmo) from Streptomyces coelicolor and D-mandelate dehydrogenase (DMD) from Rhodotorula graminis were co-expressed in an S-MA-producing strain, and the resulting strain was capable of producing 0.68 g/L R-MA. Finally, phenylpyruvate feeding experiments suggest that HmaS is a potential bottleneck to further improvement in yields. Conclusions We have constructed E. coli strains that successfully accomplished the production of S- and R-MA directly from glucose. Our work provides the first example of the completely fermentative production of S- and R-MA from renewable feedstock. PMID:21910908

ACTIVE IMMUNIZATION AGAINST POLIOMYELITIS IN MONKEYS.

PubMed

Brodie, M; Goldbloom, A

1931-05-31

1. A combination of poliomyelitis virus and specific human serum is effective for the production of active immunity. 2. For each gram of active virus given intradermally as an emulsion, 6 cc. of human immune serum, injected subcutaneously, was required in our experiments to protect a monkey from paralysis. Some degree of active immunity was induced. 3. Immunity, without symptom of the disease, was secured when the serum was given at the time of inoculation, or within 3 days preceding or following inoculation of the virus. 4. For the production of immunity, virus, preceded by serum administration, is probably less effective than when it is given simultaneously with, or before, the injection of serum. 5. The virus neutralization test is more sensitive than the direct intracerebral test for determining the production of immunity.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Czakó, Gábor, E-mail: czako@chem.elte.hu

Motivated by a recent experiment [H. Pan and K. Liu, J. Chem. Phys. 140, 191101 (2014)], we report a quasiclassical trajectory study of the O({sup 3}P) + CH{sub 4}(v{sub k} = 0, 1) → OH + CH{sub 3} [k = 1 and 3] reactions on an ab initio potential energy surface. The computed angular distributions and cross sections correlated to the OH(v = 0, 1) + CH{sub 3}(v = 0) coincident product states can be directly compared to experiment for O + CH{sub 4}(v{sub 3} = 0, 1). Both theory and experiment show that the ground-state reaction is backward scattered,more » whereas the angular distributions shift toward sideways and forward directions upon antisymmetric stretching (v{sub 3}) excitation of the reactant. Theory predicts similar behavior for the O + CH{sub 4}(v{sub 1} = 1) reaction. The simulations show that stretching excitation enhances the reaction up to about 15 kcal/mol collision energy, whereas the O + CH{sub 4}(v{sub k} = 1) reactions produce smaller cross sections for OH(v = 1) + CH{sub 3}(v = 0) than those of O + CH{sub 4}(v = 0) → OH(v = 0) + CH{sub 3}(v = 0). The former finding agrees with experiment and the latter awaits for confirmation. The computed cold OH rotational distributions of O + CH{sub 4}(v = 0) are in good agreement with experiment.« less

Constraints on Models for the Higgs Boson with Exotic Spin and Parity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Emily Hannah

The production of a Higgs boson in association with a vector boson at the Tevatron offers a unique opportunity to study models for the Higgs boson with exotic spin J and parity P assignments. At the Tevatron the V H system is produced near threshold. Different JP assignments of the Higgs boson can be distinguished by examining the behavior of the cross section near threshold. The relatively low backgrounds at the Tevatron compared to the LHC put us in a unique position to study the direct decay of the Higgs boson to fermions. If the Higgs sector is more complexmore » than predicted, studying the spin and parity of the Higgs boson in all decay modes is important. In this Thesis we will examine the WH → ℓνb¯b production and decay mode using 9.7 fb -1 of data collected by the D0 experiment in an attempt to derive constraints on models containing exotic values for the spin and parity of the Higgs boson. In particular, we will examine models for a Higgs boson with JP = 0- and JP = 2+. We use a likelihood ratio to quantify the degree to which our data are incompatible with exotic JP predictions for a range of possible production rates. Assuming the production cross section times branching ratio of the signals in the models considered is equal to the standard model prediction, the WH → ℓνb¯b mode alone is unable to reject either exotic model considered. We will also discuss the combination of the ZH → ℓℓb¯b, WH → ℓνb¯b, and V H → ννb¯b production modes at the D0 experiment and with the CDF experiment. When combining all three production modes at the D0 experiment we reject the JP = 0- and JP = 2+ hypotheses at the 97.6% CL and at the 99.0% CL, respectively, when assuming the signal production cross section times branching ratio is equal to the standard model predicted value. When combining with the CDF experiment we reject the JP = 0- and JP = 2+ hypotheses with significances of 5.0 standard deviations and 4.9 standard deviations, respectively.abstract« less

Resonant slepton production yields CMS e e j j and e p Tj j excesses

NASA Astrophysics Data System (ADS)

Allanach, Ben; Biswas, Sanjoy; Mondal, Subhadeep; Mitra, Manimala

2015-01-01

Recent CMS searches for dileptoquark production report local excesses of 2.4 σ in an e e j j channel and 2.6 σ in an e p Tj j channel. Here, we simultaneously explain both excesses with resonant slepton production in R -parity violating supersymmetry. We consider resonant slepton production, which decays to a lepton and a chargino/neutralino, followed by three-body decays of the neutralino/chargino via an R -parity violating coupling. There are regions of parameter space which are also compatible at the 95% confidence level with a 2.8 σ e e j j excess in a recent CMS WR search, while being compatible with other direct search constraints. Phase II of the GERDA neutrinoless double beta decay (0 ν β β ) experiment will probe a sizable portion of the good-fit region.

Ways of looking ahead: hierarchical planning in language production.

PubMed

Lee, Eun-Kyung; Brown-Schmidt, Sarah; Watson, Duane G

2013-12-01

It is generally assumed that language production proceeds incrementally, with chunks of linguistic structure planned ahead of speech. Extensive research has examined the scope of language production and suggests that the size of planned chunks varies across contexts (Ferreira & Swets, 2002; Wagner & Jescheniak, 2010). By contrast, relatively little is known about the structure of advance planning, specifically whether planning proceeds incrementally according to the surface structure of the utterance, or whether speakers plan according to the hierarchical relationships between utterance elements. In two experiments, we examine the structure and scope of lexical planning in language production using a picture description task. Analyses of speech onset times and word durations show that speakers engage in hierarchical planning such that structurally dependent lexical items are planned together and that hierarchical planning occurs for both direct and indirect dependencies. Copyright © 2013 Elsevier B.V. All rights reserved.

Energy dependence of J/ψ production in Au + Au collisions at s N N = 39 , 62.4  and  200 GeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adamczyk, L.; Adkins, J. K.; Agakishiev, G.

The inclusive J/ψ transverse momentum spectra and nuclear modification factors are reported at mid-rapidity (|y|<1.0) in Au + Au collisions at √sNN = 39, 62.4 and 200 GeV taken by the STAR experiment. A suppression of J/ψ production, with respect to the production in p+p scaled by the number of binary nucleon–nucleon collisions, is observed in central Au + Au collisions at these three energies. No significant energy dependence of nuclear modification factors is found within uncertainties. The measured nuclear modification factors can be described by model calculations that take into account both suppression of direct J/ψ production due tomore » the color screening effect and J/ψ regeneration from recombination of uncorrelated charm–anticharm quark pairs.« less

Neutral strange particle production in deep inelastic scattering at HERA

NASA Astrophysics Data System (ADS)

Derick, M.; Krakauer, D.; Magill, S.; Mikunas, D.; Musgrave, B.; Repond, J.; Stanek, R.; Talaga, R. L.; Zhang, H.; Ayad, R.; Bari, G.; Basile, M.; Bellagamba, L.; Boscherini, D.; Bruni, A.; Bruni, G.; Bruni, P.; Cara Romeo, G.; Castellini, G.; Chiarini, M.; Cifarelli, L.; Cindolo, F.; Contin, A.; Corradi, M.; Gialas, I.; Giusti, P.; Iacobucci, G.; Laurenti, G.; Levi, G.; Margotti, A.; Massam, T.; Nania, R.; Nemoz, C.; Palmonari, F.; Polini, A.; Sartorelli, G.; Timellini, R.; Zamora Garcia, Y.; Zichichi, A.; Bargende, A.; Crittenden, J.; Desch, K.; Diekmann, B.; Doeker, T.; Eckert, M.; Feld, L.; Frey, A.; Geerts, M.; Geitz, G.; Grothe, M.; Haas, T.; Hartmann, H.; Heinloth, K.; Hilger, E.; Jakob, H.-P.; Katz, U. F.; Mari, S. M.; Mass, A.; Mengel, S.; Mollen, J.; Paul, E.; Rembser, Ch.; Schramm, D.; Stamm, J.; Wedemeyer, R.; Campbell-Robson, S.; Cassidy, A.; Dyce, N.; Foster, B.; George, S.; Gilmore, R.; Heath, G. P.; Heath, H. F.; Llewellyn, T. J.; Morgado, C. J. S.; Norman, D. J. P.; O'Mara, J. A.; Tapper, R. J.; Wilson, S. S.; Yoshida, R.; Rau, R. R.; Arneodo, M.; Iannotti, L.; Schioppa, M.; Susinno, G.; Bernstein, A.; Caldwell, A.; Cartiglia, N.; Parsons, J. A.; Ritz, S.; Sciulli, F.; Straub, P. B.; Wai, L.; Yang, S.; Zhu, Q.; Borzemski, P.; Chwastowski, J.; Eskreys, A.; Piotrzkowski, K.; Zachara, M.; Zawiejski, L.; Adamezyk, L.; Bednarek, B.; Jeleń, K.; Kisielewska, D.; Kowalski, T.; Rulikowska-Zarębska, E.; Suszycki, L.; Zając, J.; Kotański, A.; Przybycień, M.; Bauerdick, L. A. T.; Behrens, U.; Beier, H.; Bienlein, J. K.; Coldewey, C.; Deppe, O.; Desler, K.; Drews, G.; Flasiński, M.; Gilkinson, D. J.; Glasman, C.; Göttlicher, P.; Große-Knetter, J.; Gutjahr, B.; Hain, W.; Hasell, D.; Heßling, H.; Iga, Y.; Joos, P.; Kasemann, M.; Klanner, R.; Koch, W.; Köpke, L.; Kötz, U.; Kowalski, H.; Labs, J.; Ladage, A.; Löhr, B.; Löwe, M.; Lüke, D.; Mainusch, J.; Mańczak, O.; Monteiro, T.; Ng, J. S. T.; Nickel, S.; Notz, D.; Ohrenberg, K.; Roco, M.; Rohde, M.; Roldán, J.; Schneekloth, U.; Schulz, W.; Selonke, F.; Stiliaris, E.; Surrow, B.; Voß, T.; Westphal, D.; Wolf, G.; Youngman, C.; Zhou, J. F.; Grabosch, H. J.; Kharchilava, A.; Leich, A.; Mattingly, M. C. K.; Meyer, A.; Schlenstedt, S.; Wulff, N.; Barbagli, G.; Pelfer, P.; Anzivino, G.; Maccarrone, G.; de Pasquale, S.; Votano, L.; Bamberger, A.; Eisenhardt, S.; Freidhof, A.; Söldner-Rembold, S.; Schroeder, J.; Trefzger, T.; Brook, N. H.; Bussey, P. J.; Doyle, A. T.; Fleck, J. I.; Saxon, D. H.; Utley, M. L.; Wilson, A. S.; Dannemann, A.; Holm, U.; Horstmann, D.; Neumann, T.; Sinkus, R.; Wick, K.; Badura, E.; Burow, B. D.; Hagge, L.; Lohrmann, E.; Milewski, J.; Nakahata, M.; Pavel, N.; Poelz, G.; Schott, W.; Zetsche, F.; Bacon, T. C.; Butterworth, I.; Gallo, E.; Harris, V. L.; Hung, B. Y. H.; Long, K. R.; Miller, D. B.; Morawitz, P. P. O.; Prinias, A.; Sedgbeer, J. K.; Whitfield, A. F.; Mallik, U.; McCliment, E.; Wang, M. Z.; Wang, S. M.; Wu, J. T.; Zhang, Y.; Cloth, P.; Filges, D.; An, S. H.; Hong, S. M.; Nam, S. W.; Park, S. K.; Suh, M. H.; Yon, S. H.; Imlay, R.; Kartik, S.; Kim, H.-J.; McNeil, R. R.; Metcalf, W.; Nadendla, V. K.; Barreiro, F.; Cases, G.; Fernandez, J. P.; Graciani, R.; Hernández, J. M.; Hervás, L.; Labarga, L.; Martinez, M.; Del Peso, J.; Puga, J.; Terron, J.; de Trocóniz, J. F.; Smith, G. R.; Corriveau, F.; Hanna, D. S.; Hartmann, J.; Hung, L. W.; Lim, J. N.; Matthews, C. G.; Patel, P. M.; Sinclair, L. E.; Stairs, D. G.; Laurent, M. St.; Ullmann, R.; Zacek, G.; Bashkirov, V.; Dolgoshein, B. A.; Stifutkin, A.; Bashindzhagyan, G. L.; Ermolov, P. F.; Gladilin, L. K.; Golubkov, Y. A.; Kobrin, V. D.; Kuzmin, V. A.; Proskuryakov, A. S.; Savin, A. A.; Shcheglova, L. M.; Solomin, A. N.; Zotov, N. P.; Botje, M.; Chlebana, F.; Dake, A.; Engelen, J.; de Kamps, M.; Kooijman, P.; Kruse, A.; Tiecke, H.; Verkerke, W.; Vreeswijk, M.; Wiggers, L.; de Wolf, E.; van Woudenberg, R.; Acosta, D.; Bylsma, B.; Durkin, L. S.; Honscheid, K.; Li, C.; Ling, T. Y.; McLean, K. W.; Murray, W. N.; Park, I. H.; Romanowski, T. A.; Seidlein, R.; Bailey, D. S.; Byrne, A.; Cashmore, R. J.; Cooper-Sarkar, A. M.; Devenish, R. C. E.; Harnew, N.; Lancaster, M.; Lindemann, L.; McFall, J. D.; Nath, C.; Noyes, V. A.; Quadt, A.; Tickner, J. R.; Uijterwaal, H.; Walczak, R.; Waters, D. S.; Wilson, F. F.; Yip, T.; Abbrendi, G.; Bertolin, A.; Brugnera, R.; Carlin, R.; Dal Corso, F.; de Giorgi, M.; Dosselli, U.; Limentani, S.; Morandin, M.; Posocco, M.; Stanco, L.; Stroili, R.; Voci, C.; Bulmahn, J.; Butterworth, J. M.; Feild, R. G.; Oh, B. Y.; Whitmore, J. J.; D'Agostini, G.; Marini, G.; Nigro, A.; Tassi, E.; Hart, J. C.; McCubbin, N. A.; Prytz, K.; Shah, T. P.; Short, T. L.; Barberis, E.; Dubbs, T.; Heusch, C.; van Hook, M.; Hubbard, B.; Lockman, W.; Rahn, J. T.; Sadrozinski, H. F.-W.; Seiden, A.; Biltzinger, J.; Seifert, R. J.; Schwarzer, O.; Walenta, A. H.; Zech, G.; Abramowicz, H.; Briskin, G.; Dagan, S.; Levy, A.; Hasegawa, T.; Hazumi, M.; Ishii, T.; Kuze, M.; Mine, S.; Nagasawa, Y.; Nakao, M.; Suzuki, I.; Tokushuku, K.; Yamada, S.; Yamazaki, Y.; Chiba, M.; Hamatsu, R.; Hirose, T.; Homma, K.; Kitamura, S.; Nakamitsu, Y.; Yamauchi, K.; Cirio, R.; Costa, M.; Ferrero, M. I.; Lamberti, L.; Maselli, S.; Peroni, C.; Sacchi, R.; Solano, A.; Staiano, A.; Dardo, M.; Bailey, D. C.; Bandyopadhyay, D.; Benard, F.; Brkic, M.; Crombie, M. B.; Gingrich, D. M.; Hartner, G. F.; Joo, K. K.; Leyman, G. M.; Martin, J. F.; Orr, R. S.; Sampson, C. R.; Teuscher, R. J.; Catterall, C. D.; Jones, T. W.; Kaziewicz, P. B.; Lane, J. B.; Saunders, R. L.; Shulman, J.; Blankenship, K.; Lu, B.; Mo, L. W.; Bogusz, W.; Charchula, K.; Ciborowski, J.; Gajewski, J.; Grzelak, G.; Kasprzak, M.; Krzyżanowski, M.; Muchorowski, K.; Nowak, R. J.; Pawlak, J. M.; Tymieniecka, T.; Wróblewski, A. K.; Zakrzewski, J. A.; Żarnecki, A. F.; Adamus, M.; Eisenberg, Y.; Karshon, U.; Revel, D.; Zer-Zion, D.; Ali, I.; Badgett, W. F.; Behrens, B.; Dasu, S.; Fordham, C.; Foudas, C.; Goussiou, A.; Loveless, R. J.; Reeder, D. D.; Silverstein, S.; Smith, W. H.; Vaiciulis, A.; Wodarczyk, M.; Tsurugai, T.; Bhadra, S.; Cardy, M. L.; Fagerstroem, C.-P.; Frisken, W. R.; Furutani, K. M.; Khakzad, M.; Schmidke, W. B.

1995-03-01

This paper presents measurements of K 0 and Λ production in neutral current, deep inelastic scattering of 26.7 GeV electrons and 820 GeV protons in the kinematic range 10< Q 2<640 GeV2, 0.0003< x<0.01, and y>0.04. Average multiplicities for K 0 and Λ production are determined for transverse momenta p T>0.5 GeV and pseudorapidities |η|<1.3. The multiplicities favour a stronger strange to light quark suppression in the fragmentation chain than found in e + e - experiments. The production properties of K 0' s in events with and without a large rapidity gap with respect to the proton direction are compared. The ratio of neutral K 0' s to charged particles per event in the measured kinematic range is, within the present statistics, the same in both samples.

Energy dependence of J/ψ production in Au + Au collisions at s N N = 39 , 62.4  and  200 GeV

DOE PAGES

Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; ...

2017-05-10

The inclusive J/ψ transverse momentum spectra and nuclear modification factors are reported at mid-rapidity (|y|<1.0) in Au + Au collisions at √sNN = 39, 62.4 and 200 GeV taken by the STAR experiment. A suppression of J/ψ production, with respect to the production in p+p scaled by the number of binary nucleon–nucleon collisions, is observed in central Au + Au collisions at these three energies. No significant energy dependence of nuclear modification factors is found within uncertainties. The measured nuclear modification factors can be described by model calculations that take into account both suppression of direct J/ψ production due tomore » the color screening effect and J/ψ regeneration from recombination of uncorrelated charm–anticharm quark pairs.« less

Cost-effective monolithic and hybrid integration for metro and long-haul applications

NASA Astrophysics Data System (ADS)

Clayton, Rick; Carter, Andy; Betty, Ian; Simmons, Timothy

2003-12-01

Today's telecommunication market is characterized by conservative business practices: tight management of costs, low risk investing and incremental upgrades, rather than the more freewheeling approach taken a few years ago. Optimizing optical components for the current and near term market involves substantial integration, but within particular bounds. The emphasis on evolution, in particular, has led to increased standardization of functions and so created extensive opportunities for integrated product offerings. The same standardization that enables commercially successful integrated functions also changes the competitive environment, and changes the emphasis for component development; shifting the innovation priority from raw performance to delivering the most effective integrated products. This paper will discuss, with specific examples from our transmitter, receiver and passives product families, our understanding of the issues based on extensive experience in delivering high end integrated products to the market, and the direction it drives optical components.

DOE Office of Scientific and Technical Information (OSTI.GOV)

S.K. Kawatra; B. Anamerie; T.C. Eisele

The pig iron nugget process was developed as an alternative to the traditional blast furnace process by Kobe Steel. The process aimed to produce pig iron nuggets, which have similar chemical and physical properties to blast furnace pig iron, in a single step. The pig iron nugget process utilizes coal instead of coke and self reducing and fluxing dried green balls instead of pellets and sinters. In this process the environmental emissions caused by coke and sinter production, and energy lost between pellet induration (heat hardening) and transportation to the blast furnace can be eliminated. The objectives of this researchmore » were to (1) produce pig iron nuggets in the laboratory, (2) characterize the pig iron nugget produced and compare them with blast furnace pig iron, (3) investigate the furnace temperature and residence time effects on the pig iron nugget production, and (4) optimize the operational furnace temperatures and residence times. The experiments involved heat treatment of self reducing and fluxing dried green balls at various furnace temperatures and residence times. Three chemically and physically different products were produced after the compete reduction of iron oxides to iron depending on the operational furnace temperatures and/or residence times. These products were direct reduced iron (DRI), transition direct reduced iron (TDRI), and pig iron nuggets. The increase in the carbon content of the system as a function of furnace temperature and/or residence time dictated the formation of these products. The direct reduced iron, transition direct reduced iron, and pig iron nuggets produced were analyzed for their chemical composition, degree of metallization, apparent density, microstructure and microhardness. In addition, the change in the carbon content of the system with the changing furnace temperature and/or residence time was detected by optical microscopy and Microhardness measurements. The sufficient carbon dissolution required for the production of pig iron nuggets was determined. It was determined that pig iron nuggets produced had a high apparent density (6.7-7.2 gr/cm3), highly metallized, slag free structure, high iron content (95-97%), high microhardness values (> 325 HVN) and microstructure similar to white cast iron. These properties made them a competitive alternative to blast furnace pig iron.« less

Lowering the radioactivity of the photomultiplier tubes for the XENON1T dark matter experiment

DOE PAGES

Aprile, E.; Agostini, F.; Alfonsi, M.; ...

2015-11-23

The low-background, VUV-sensitive 3-inch diameter photomultiplier tube R11410 has been developed by Hamamatsu for dark matter direct detection experiments using liquid xenon as the target material. We present the results from the joint effort between the XENON collaboration and the Hamamatsu company to produce a highly radio-pure photosensor (version R11410-21) for the XENON1T dark matter experiment. After introducing the photosensor and its components, we show the methods and results of the radioactive contamination measurements of the individual materials employed in the photomultiplier production. We then discuss the adopted strategies to reduce the radioactivity of the various PMT versions. Finally, wemore » detail the results from screening 286 tubes with ultra-low background germanium detectors, as well as their implications for the expected electronic and nuclear recoil background of the XENON1T experiment.« less

The H2 + + He proton transfer reaction: quantum reactive differential cross sections to be linked with future velocity mapping experiments

NASA Astrophysics Data System (ADS)

Hernández Vera, Mario; Wester, Roland; Gianturco, Francesco Antonio

2018-01-01

We construct the velocity map images of the proton transfer reaction between helium and molecular hydrogen ion {{{H}}}2+. We perform simulations of imaging experiments at one representative total collision energy taking into account the inherent aberrations of the velocity mapping in order to explore the feasibility of direct comparisons between theory and future experiments planned in our laboratory. The asymptotic angular distributions of the fragments in a 3D velocity space is determined from the quantum state-to-state differential reactive cross sections and reaction probabilities which are computed by using the time-independent coupled channel hyperspherical coordinate method. The calculations employ an earlier ab initio potential energy surface computed at the FCI/cc-pVQZ level of theory. The present simulations indicate that the planned experiments would be selective enough to differentiate between product distributions resulting from different initial internal states of the reactants.

Forces and moments generated by the human arm: Variability and control

PubMed Central

Xu, Y; Terekhov, AV; Latash, ML; Zatsiorsky, VM

2012-01-01

This is an exploratory study of the accurate endpoint force vector production by the human arm in isometric conditions. We formulated three common-sense hypotheses and falsified them in the experiment. The subjects (n=10) exerted static forces on the handle in eight directions in a horizontal plane for 25 seconds. The forces were of 4 magnitude levels (10 %, 20%, 30% and 40% of individual MVC). The torsion moment on the handle (grasp moment) was not specified in the instruction. The two force components and the grasp moment were recorded, and the shoulder, elbow, and wrist joint torques were computed. The following main facts were observed: (a) While the grasp moment was not prescribed by the instruction, it was always produced. The moment magnitude and direction depended on the instructed force magnitude and direction. (b) The within-trial angular variability of the exerted force vector (angular precision) did not depend on the target force magnitude (a small negative correlation was observed). (c) Across the target force directions, the variability of the exerted force magnitude and directional variability exhibited opposite trends: In the directions where the variability of force magnitude was maximal, the directional variability was minimal and vice versa. (d) The time profiles of joint torques in the trials were always positively correlated, even for the force directions where flexion torque was produced at one joint and extension torque was produced at the other joint. (e) The correlations between the grasp moment and the wrist torque were negative across the tasks and positive within the individual trials. (f) In static serial kinematic chains, the pattern of the joint torques distribution could not be explained by an optimization cost function additive with respect to the torques. Plans for several future experiments have been suggested. PMID:23080084

Medium effects in λK+ pair production by 2.83 GeV protons on nuclei

NASA Astrophysics Data System (ADS)

Paryev, E. Ya.; Hartmann, M.; Kiselev, Yu. T.

2017-12-01

We study ΛK+ pair production in the interaction of protons of 2.83 GeV kinetic energy with C, Cu, Ag, and Au target nuclei in the framework of the nuclear spectral function approach for incoherent primary proton-nucleon and secondary pion-nucleon production processes, and processes associated with the creation of intermediate Σ0K+ pairs. The approach accounts for the initial proton and final Λ hyperon absorption, final K+ meson distortion in nuclei, target nucleon binding, and Fermi motion, as well as nuclear mean-field potential effects on these processes. We calculate the Λ momentum dependence of the absolute ΛK+ yield from the target nuclei considered, in the kinematical conditions of the ANKE experiment, performed at COSY, within the different scenarios for the Λ-nucleus effective scalar potential. We show that the above observable is appreciably sensitive to this potential in the low-momentum region. Therefore, direct comparison of the results of our calculations with the data from the ANKE-at-COSY experiment can help to determine the above potential at finite momenta. We also demonstrate that the two-step pion-nucleon production channels dominate in the low-momentum ΛK+ production in the chosen kinematics and, therefore, they have to be taken into account in the analysis of these data. Supported by the Ministry of Education and Science of the Russian Federation

Experimenting `learn by doing' and `learn by failing'

NASA Astrophysics Data System (ADS)

Pozzi, Rossella; Noè, Carlo; Rossi, Tommaso

2015-01-01

According to the literature, in recent years, developing experiential learning has fulfilled the requirement of a deep understanding of lean philosophy by engineering students, demonstrating the advantages and disadvantages of some of the key principles of lean manufacturing. On the other hand, the literature evidences how some kinds of game-based experiential learning overlook daily difficulties, which play a central role in manufacturing systems. To fill the need of a game overcoming such lack of vision, an innovative game direct in-field, named Kart Factory, has been developed. Actual production shifts are simulated, while keeping all the elements peculiar to a real production set (i.e. complexity, effort, safety). The working environment is a real pedal car assembly department, the products to be assembled have relevant size and weight (i.e. up to 35 kg approximately), and the provided tools are real production equipment (e.g. keys, screwdrivers, trans-pallets, etc.). Due to the need to maximise the impact on students, a labour-intensive process characterises the production department. The whole training process is based on three educational principles: Experience Value Principle, Error Value Principle, and Team Value Principle. As the 'learn by doing' and 'learn by failing' are favoured, the theory follows the practice, while crating the willingness to 'do' instead of just designing or planning. The gathered data prove the Kart Factory's effectiveness in reaching a good knowledge of lean concepts, notwithstanding the students' initial knowledge level.

Speech monitoring and phonologically-mediated eye gaze in language perception and production: a comparison using printed word eye-tracking

PubMed Central

Gauvin, Hanna S.; Hartsuiker, Robert J.; Huettig, Falk

2013-01-01

The Perceptual Loop Theory of speech monitoring assumes that speakers routinely inspect their inner speech. In contrast, Huettig and Hartsuiker (2010) observed that listening to one's own speech during language production drives eye-movements to phonologically related printed words with a similar time-course as listening to someone else's speech does in speech perception experiments. This suggests that speakers use their speech perception system to listen to their own overt speech, but not to their inner speech. However, a direct comparison between production and perception with the same stimuli and participants is lacking so far. The current printed word eye-tracking experiment therefore used a within-subjects design, combining production and perception. Displays showed four words, of which one, the target, either had to be named or was presented auditorily. Accompanying words were phonologically related, semantically related, or unrelated to the target. There were small increases in looks to phonological competitors with a similar time-course in both production and perception. Phonological effects in perception however lasted longer and had a much larger magnitude. We conjecture that this difference is related to a difference in predictability of one's own and someone else's speech, which in turn has consequences for lexical competition in other-perception and possibly suppression of activation in self-perception. PMID:24339809

Heavy rainfall increases nestling mortality of an Arctic top predator: experimental evidence and long-term trend in peregrine falcons.

PubMed

Anctil, Alexandre; Franke, Alastair; Bêty, Joël

2014-03-01

Although animal population dynamics have often been correlated with fluctuations in precipitation, causal relationships have rarely been demonstrated in wild birds. We combined nest observations with a field experiment to investigate the direct effect of rainfall on survival of peregrine falcon (Falco peregrinus) nestlings in the Canadian Arctic. We then used historical data to evaluate if recent changes in the precipitation regime could explain the long-term decline of falcon annual productivity. Rainfall directly caused more than one-third of the recorded nestling mortalities. Juveniles were especially affected by heavy rainstorms (≥8 mm/day). Nestlings sheltered from rainfall by a nest box had significantly higher survival rates. We found that the increase in the frequency of heavy rain over the last three decades is likely an important factor explaining the recent decline in falcon nestling survival rates, and hence the decrease in annual breeding productivity of the population. Our study is among the first experimental demonstrations of the direct link between rainfall and survival in wild birds, and clearly indicates that top arctic predators can be significantly impacted by changes in precipitation regime.

Controlled sound field with a dual layer loudspeaker array

NASA Astrophysics Data System (ADS)

Shin, Mincheol; Fazi, Filippo M.; Nelson, Philip A.; Hirono, Fabio C.

2014-08-01

Controlled sound interference has been extensively investigated using a prototype dual layer loudspeaker array comprised of 16 loudspeakers. Results are presented for measures of array performance such as input signal power, directivity of sound radiation and accuracy of sound reproduction resulting from the application of conventional control methods such as minimization of error in mean squared pressure, maximization of energy difference and minimization of weighted pressure error and energy. Procedures for selecting the tuning parameters have also been introduced. With these conventional concepts aimed at the production of acoustically bright and dark zones, all the control methods used require a trade-off between radiation directivity and reproduction accuracy in the bright zone. An alternative solution is proposed which can achieve better performance based on the measures presented simultaneously by inserting a low priority zone named as the “gray” zone. This involves the weighted minimization of mean-squared errors in both bright and dark zones together with the gray zone in which the minimization error is given less importance. This results in the production of directional bright zone in which the accuracy of sound reproduction is maintained with less required input power. The results of simulations and experiments are shown to be in excellent agreement.

Direct observation of ClO from chlorine nitrate photolysis. [as mechanism of polar ozone depletion

NASA Technical Reports Server (NTRS)

Minton, Timothy K.; Nelson, Christine M.; Moore, Teresa A.; Okumura, Mitchio

1992-01-01

Chlorine nitrate photolysis has been investigated with the use of a molecular beam technique. Excitation at both 248 and 193 nanometers led to photodissociation by two pathways, ClONO2 yields ClO + NO2 and ClONO2 yields Cl + NO3, with comparable yields. This experiment provides a direct measurement of the ClO product channel and consequently raises the possibility of an analogous channel in ClO dimer photolysis. Photodissociation of the ClO dimer is a critical step in the catalytic cycle that is presumed to dominate polar stratospheric ozone destruction. A substantial yield of ClO would reduce the efficiency of this cycle.

Site selection and directional models of deserts used for ERBE validation targets

NASA Technical Reports Server (NTRS)

Staylor, W. F.

1986-01-01

Broadband shortwave and longwave radiance measurements obtained from the Nimbus 7 Earth Radiation Budget scanner were used to develop reflectance and emittance models for the Sahara, Gibson, and Saudi Deserts. These deserts will serve as in-flight validation targets for the Earth Radiation Budget Experiment being flown on the Earth Radiation Budget Satellite and two National Oceanic and Atmospheric Administration polar satellites. The directional reflectance model derived for the deserts was a function of the sum and product of the cosines of the solar and viewing zenith angles, and thus reciprocity existed between these zenith angles. The emittance model was related by a power law of the cosine of the viewing zenith angle.

The medicinal use of cannabis and cannabinoids--an international cross-sectional survey on administration forms.

PubMed

Hazekamp, Arno; Ware, Mark A; Muller-Vahl, Kirsten R; Abrams, Donald; Grotenhermen, Franjo

2013-01-01

Cannabinoids, including tetrahydrocannabinol and cannabidiol, are the most important active constituents of the cannabis plant. Over recent years, cannabinoid-based medicines (CBMs) have become increasingly available to patients in many countries, both as pharmaceutical products and as herbal cannabis (marijuana). While there seems to be a demand for multiple cannabinoid-based therapeutic products, specifically for symptomatic amelioration in chronic diseases, therapeutic effects of different CBMs have only been directly compared in a few clinical studies. The survey presented here was performed by the International Association for Cannabinoid Medicines (IACM), and is meant to contribute to the understanding of cannabinoid-based medicine by asking patients who used cannabis or cannabinoids detailed questions about their experiences with different methods of intake. The survey was completed by 953 participants from 31 countries, making this the largest international survey on a wide variety of users of cannabinoid-based medicine performed so far. In general, herbal non-pharmaceutical CBMs received higher appreciation scores by participants than pharmaceutical products containing cannabinoids. However, the number of patients who reported experience with pharmaceutical products was low, limiting conclusions on preferences. Nevertheless, the reported data may be useful for further development of safe and effective medications based on cannabis and single cannabinoids.

Origins and Scaling of Hot-Electron Preheat in Ignition-Scale Direct-Drive Inertial Confinement Fusion Experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenberg, M. J.; Solodov, A. A.; Myatt, J. F.

Planar laser-plasma interaction (LPI) experiments at the National Ignition Facility (NIF) have allowed access for the rst time to regimes of electron density scale length (~500 to 700 μm), electron temperature (~3 to 5 keV), and laser intensity (6 to 16 x 10 14 W/cm 2) that are relevant to direct-drive inertial confinement fusion ignition. Unlike in shorter-scale-length plasmas on OMEGA, scattered-light data on the NIF show that the near-quarter-critical LPI physics is dominated by stimulated Raman scattering (SRS) rather than by two-plasmon decay (TPD). This difference in regime is explained based on absolute SRS and TPD threshold considerations. SRSmore » sidescatter tangential to density contours and other SRS mechanisms are observed. The fraction of laser energy converted to hot electrons is ~0.7% to 2.9%, consistent with observed levels of SRS. The intensity threshold for hot-electron production is assessed, and the use of a Si ablator slightly increases this threshold from ~4 x 10 14 to ~6 x 10 14 W/cm 2. These results have significant implications for mitigation of LPI hot-electron preheat in direct-drive ignition designs.« less

Origins and Scaling of Hot-Electron Preheat in Ignition-Scale Direct-Drive Inertial Confinement Fusion Experiments

DOE PAGES

Rosenberg, M. J.; Solodov, A. A.; Myatt, J. F.; ...

2018-01-29

Planar laser-plasma interaction (LPI) experiments at the National Ignition Facility (NIF) have allowed access for the rst time to regimes of electron density scale length (~500 to 700 μm), electron temperature (~3 to 5 keV), and laser intensity (6 to 16 x 10 14 W/cm 2) that are relevant to direct-drive inertial confinement fusion ignition. Unlike in shorter-scale-length plasmas on OMEGA, scattered-light data on the NIF show that the near-quarter-critical LPI physics is dominated by stimulated Raman scattering (SRS) rather than by two-plasmon decay (TPD). This difference in regime is explained based on absolute SRS and TPD threshold considerations. SRSmore » sidescatter tangential to density contours and other SRS mechanisms are observed. The fraction of laser energy converted to hot electrons is ~0.7% to 2.9%, consistent with observed levels of SRS. The intensity threshold for hot-electron production is assessed, and the use of a Si ablator slightly increases this threshold from ~4 x 10 14 to ~6 x 10 14 W/cm 2. These results have significant implications for mitigation of LPI hot-electron preheat in direct-drive ignition designs.« less

Fourteen-month-old infants use interpersonal synchrony as a cue to direct helpfulness

PubMed Central

Cirelli, Laura K.; Wan, Stephanie J.; Trainor, Laurel J.

2014-01-01

Musical behaviours such as dancing, singing and music production, which require the ability to entrain to a rhythmic beat, encourage high levels of interpersonal coordination. Such coordination has been associated with increased group cohesion and social bonding between group members. Previously, we demonstrated that this association influences even the social behaviour of 14-month-old infants. Infants were significantly more likely to display helpfulness towards an adult experimenter following synchronous bouncing compared with asynchronous bouncing to music. The present experiment was designed to determine whether interpersonal synchrony acts as a cue for 14-month-olds to direct their prosocial behaviours to specific individuals with whom they have experienced synchronous movement, or whether it acts as a social prime, increasing prosocial behaviour in general. Consistent with the previous results, infants were significantly more likely to help an experimenter following synchronous versus asynchronous movement with this person. Furthermore, this manipulation did not affect infant's behaviour towards a neutral stranger, who was not involved in any movement experience. This indicates that synchronous bouncing acts as a social cue for directing prosociality. These results have implications for how musical engagement and rhythmic synchrony affect social behaviour very early in development. PMID:25385778

Origins and Scaling of Hot-Electron Preheat in Ignition-Scale Direct-Drive Inertial Confinement Fusion Experiments

NASA Astrophysics Data System (ADS)

Rosenberg, M. J.; Solodov, A. A.; Myatt, J. F.; Seka, W.; Michel, P.; Hohenberger, M.; Short, R. W.; Epstein, R.; Regan, S. P.; Campbell, E. M.; Chapman, T.; Goyon, C.; Ralph, J. E.; Barrios, M. A.; Moody, J. D.; Bates, J. W.

2018-01-01

Planar laser-plasma interaction (LPI) experiments at the National Ignition Facility (NIF) have allowed access for the first time to regimes of electron density scale length (˜500 to 700 μ m ), electron temperature (˜3 to 5 keV), and laser intensity (6 to 16 ×1014 W /cm2 ) that are relevant to direct-drive inertial confinement fusion ignition. Unlike in shorter-scale-length plasmas on OMEGA, scattered-light data on the NIF show that the near-quarter-critical LPI physics is dominated by stimulated Raman scattering (SRS) rather than by two-plasmon decay (TPD). This difference in regime is explained based on absolute SRS and TPD threshold considerations. SRS sidescatter tangential to density contours and other SRS mechanisms are observed. The fraction of laser energy converted to hot electrons is ˜0.7 % to 2.9%, consistent with observed levels of SRS. The intensity threshold for hot-electron production is assessed, and the use of a Si ablator slightly increases this threshold from ˜4×10 14 to ˜6 ×1014 W /cm2 . These results have significant implications for mitigation of LPI hot-electron preheat in direct-drive ignition designs.

Search for direct top squark pair production in final states with two tau leptons in pp collisions at [Formula: see text] TeV with the ATLAS detector.

PubMed

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Zhukov, K; Zibell, A; Zieminska, D; Zimine, N I; Zimmermann, C; Zimmermann, S; Zinonos, Z; Zinser, M; Ziolkowski, M; Živković, L; Zobernig, G; Zoccoli, A; Zur Nedden, M; Zurzolo, G; Zwalinski, L

A search for direct pair production of the supersymmetric partner of the top quark, decaying via a scalar tau to a nearly massless gravitino, has been performed using 20 fb[Formula: see text] of proton-proton collision data at [Formula: see text]. The data were collected by the ATLAS experiment at the LHC in 2012. Top squark candidates are searched for in events with either two hadronically decaying tau leptons, one hadronically decaying tau and one light lepton, or two light leptons. No significant excess over the Standard Model expectation is found. Exclusion limits at [Formula: see text] confidence level are set as a function of the top squark and scalar tau masses. Depending on the scalar tau mass, ranging from the [Formula: see text] LEP limit to the top squark mass, lower limits between 490 and [Formula: see text] are placed on the top squark mass within the model considered.

Biodiesel production from Spirulina microalgae feedstock using direct transesterification near supercritical methanol condition.

PubMed

Mohamadzadeh Shirazi, Hamed; Karimi-Sabet, Javad; Ghotbi, Cyrus

2017-09-01

Microalgae as a candidate for production of biodiesel, possesses a hard cell wall that prevents intracellular lipids leaving out from the cells. Direct or in situ supercritical transesterification has the potential for destruction of microalgae hard cell wall and conversion of extracted lipids to biodiesel that consequently reduces the total energy consumption. Response surface methodology combined with central composite design was applied to investigate process parameters including: Temperature, Time, Methanol-to-dry algae, Hexane-to-dry algae, and Moisture content. Thirty-two experiments were designed and performed in a batch reactor, and biodiesel efficiency between 0.44% and 99.32% was obtained. According to fatty acid methyl ester yields, a quadratic experimental model was adjusted and the significance of parameters was evaluated using analysis of variance (ANOVA). Effects of single and interaction parameters were also interpreted. In addition, the effect of supercritical process on the ultrastructure of microalgae cell wall using scanning electron spectrometry (SEM) was surveyed. Copyright © 2017 Elsevier Ltd. All rights reserved.

A Survey of Direct Users and Uses of SNOMED CT: 2010 Status

PubMed Central

Elhanan, Gai; Perl, Yehoshua; Geller, James

2010-01-01

SNOMED CT is gaining momentum and endorsements as an international clinical terminology. However, many vendors await a clearer business case and clients’ demand. We conducted a survey of direct users of SNOMED CT to determine the current profile of users, modes of use, and attitudes towards different aspects of the terminology. A web-base survey, consisting of 43 questions was distributed in January 2010, and 215 responses were elicited. This paper summarizes findings regarding profiles of users and their SNOMED CT use. The results indicate significant use by non-researchers and by industry and government sectors. Many users are relative newcomers with less than 3 years experience with SNOMED CT, and production-related use was reported by 39% of respondents. Most users are satisfied with the level of content coverage. The results indicate that SNOMED CT has a solid footing in production systems, and that SCT is mostly used for concept searches and clinical coding. PMID:21346970

Study of temperature characterization of agricultural waste in the development of stove for combine heat power

NASA Astrophysics Data System (ADS)

Yulianto, Muhamad; Agustina, Sri Endah; Hartulistiyoso, Edy; Nelwan, Leopold Oscar; Nurlela

2017-03-01

Indonesia is one of tropical country in the world, therefore biomass product can find a lot in Indonesia. In the other side, waste of agricultural product is one of biomass resources which is can be converting to energy using Combine Heat Power for the example. In this paper, will be discussed about the temperature characterization due to influence of feeding rate and air flow rate. The contribution of this paper will show the temperature achievement of flue gas as the result of direct combustion in a stove. The research conducted using coconut shell as raw fuel material with varying feed rate and air flow rate. In this research also use the excess air to know the effect. The result show that the temperature of flue gas in direct combustion of coconut shell can reach of 520°C and temperature at combustion chamber reach 840°C. This achievement is occurring in the certain variation of experiment.

Directed evolution of enzymes using microfluidic chips

NASA Astrophysics Data System (ADS)

Pilát, Zdeněk.; Ježek, Jan; Šmatlo, Filip; Kaůka, Jan; Zemánek, Pavel

2016-12-01

Enzymes are highly versatile and ubiquitous biological catalysts. They can greatly accelerate large variety of reactions, while ensuring appropriate catalytic activity and high selectivity. These properties make enzymes attractive biocatalysts for a wide range of industrial and biomedical applications. Over the last two decades, directed evolution of enzymes has transformed the field of protein engineering. We have devised microfluidic systems for directed evolution of haloalkane dehalogenases in emulsion droplets. In such a device, individual bacterial cells producing mutated variants of the same enzyme are encapsulated in microdroplets and supplied with a substrate. The conversion of a substrate by the enzyme produced by a single bacterium changes the pH in the droplet which is signalized by pH dependent fluorescence probe. The droplets with the highest enzymatic activity can be separated directly on the chip by dielectrophoresis and the resultant cell lineage can be used for enzyme production or for further rounds of directed evolution. This platform is applicable for fast screening of large libraries in directed evolution experiments requiring mutagenesis at multiple sites of a protein structure.

First measurements of deuterium-tritium and deuterium-deuterium fusion reaction yields in ignition-scalable direct-drive implosions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forrest, C. J.; Radha, P. B.; Knauer, J. P.

In this study, the deuterium-tritium (D-T) and deuterium-deuterium neutron yield ratio in cryogenic inertial confinement fusion (ICF) experiments is used to examine multifluid effects, traditionally not included in ICF modeling. This ratio has been measured for ignition-scalable direct-drive cryogenic DT implosions at the Omega Laser Facility using a high-dynamic-range neutron time-of-flight spectrometer. The experimentally inferred yield ratio is consistent with both the calculated values of the nuclear reaction rates and the measured preshot target-fuel composition. These observations indicate that the physical mechanisms that have been proposed to alter the fuel composition, such as species separation of the hydrogen isotopes, aremore » not significant during the period of peak neutron production in ignition-scalable cryogenic direct-drive DT implosions.« less

First measurements of deuterium-tritium and deuterium-deuterium fusion reaction yields in ignition-scalable direct-drive implosions

DOE PAGES

Forrest, C. J.; Radha, P. B.; Knauer, J. P.; ...

2017-03-03

In this study, the deuterium-tritium (D-T) and deuterium-deuterium neutron yield ratio in cryogenic inertial confinement fusion (ICF) experiments is used to examine multifluid effects, traditionally not included in ICF modeling. This ratio has been measured for ignition-scalable direct-drive cryogenic DT implosions at the Omega Laser Facility using a high-dynamic-range neutron time-of-flight spectrometer. The experimentally inferred yield ratio is consistent with both the calculated values of the nuclear reaction rates and the measured preshot target-fuel composition. These observations indicate that the physical mechanisms that have been proposed to alter the fuel composition, such as species separation of the hydrogen isotopes, aremore » not significant during the period of peak neutron production in ignition-scalable cryogenic direct-drive DT implosions.« less

The phenomenology of maverick dark matter

NASA Astrophysics Data System (ADS)

Krusberg, Zosia Anna Celina

Astrophysical observations from galactic to cosmological scales point to a substantial non-baryonic component to the universe's total matter density. Although very little is presently known about the physical properties of dark matter, its existence offers some of the most compelling evidence for physics beyond the standard model (BSM). In the weakly interacting massive particle (WIMP) scenario, the dark matter consists of particles that possess weak-scale interactions with the particles of the standard model, offering a compelling theoretical framework that allows us to understand the relic abundance of dark matter as a natural consequence of the thermal history of the early universe. From the perspective of particle physics phenomenology, the WIMP scenario is appealing for two additional reasons. First, many theories of BSM physics contain attractive WIMP candidates. Second, the weak-scale interactions between WIMPs and standard model particles imply the possibility of detecting scatterings between relic WIMPs and detector nuclei in direct detection experiments, products of WIMP annihilations at locations throughout the galaxy in indirect detection programs, and WIMP production signals at high-energy particle colliders. In this work, we use an effective field theory approach to study model-independent dark matter phenomenology in direct detection and collider experiments. The maverick dark matter scenario is defined by an effective field theory in which the WIMP is the only new particle within the energy range accessible to the Large Hadron Collider (LHC). Although certain assumptions are necessary to keep the problem tractable, we describe our WIMP candidate generically by specifying only its spin and dominant interaction form with standard model particles. Constraints are placed on the masses and coupling constants of the maverick WIMPs using the Wilkinson Microwave Anisotropy Probe (WMAP) relic density measurement and direct detection exclusion data from both spin-independent (XENON100 and SuperCDMS) and spin-dependent (COUPP) experiments. We further study the distinguishability of maverick WIMP production signals at the Tevatron and the LHC---at its early and nominal configurations---using standard simulation packages, place constraints on maverick WIMP properties using existing collider data, and determine projected mass reaches in future data from both colliders. We find ourselves in a unique era of theoretically-motivated, high-precision dark matter searches that hold the potential to give us important insights, not only into the nature of dark matter, but also into the physics that lies beyond the standard model.

Direct dynamics trajectory study of the reaction of formaldehyde cation with D2: vibrational and zero-point energy effects on quasiclassical trajectories.

PubMed

Liu, Jianbo; Song, Kihyung; Hase, William L; Anderson, Scott L

2005-12-22

Quasiclassical, direct dynamics trajectories have been used to study the reaction of formaldehyde cation with molecular hydrogen, simulating the conditions in an experimental study of H2CO+ vibrational effects on this reaction. Effects of five different H2CO+ modes were probed, and we also examined different approaches to treating zero-point energy in quasiclassical trajectories. The calculated absolute cross-sections are in excellent agreement with experiments, and the results provide insight into the reaction mechanism, product scattering behavior, and energy disposal, and how they vary with impact parameter and reactant state. The reaction is sharply orientation-dependent, even at high collision energies, and both trajectories and experiment find that H2CO+ vibration inhibits reaction. On the other hand, the trajectories do not reproduce the anomalously strong effect of nu2(+) (the CO stretch). The origin of the discrepancy and approaches for minimizing such problems in quasiclassical trajectories are discussed.

Geomagnetic paleointensities from excursion sequences in lavas on Oahu, Hawaii

USGS Publications Warehouse

Coe, Robert S.; Gromme, Sherman; Mankinen, Edward A.

1984-01-01

Paleomagnetic data demonstrating three late Tertiary excursions in the direction of the geomagnetic field recorded in sequences of basaltic lavas on the island of Oahu, Hawaii were published by R. R. Doell and G. B. Dalrymple in 1973. We have determined geomagnetic paleointensities by the Thelliers' method for 14 lavas from the three sites. During these experiments, considerable difficulty was encountered because of the presence of titanomaghemite in many lavas and the contamination of natural remanent magnetization by lightning in many others. Moreover, we often observed the production of spurious high‐temperature chemical remanent magnetization during the Thellier experiments. An analysis of this particularly troublesome problem is presented. Two of the sites showed low paleointensities associated with angular departures of the paleomagnetic field direction from that of a geocentric axial dipole, which suggests that these excursions represent aborted reversals or fragments of reversals. At the third site, however, the paleointensity did not become low as the field diverged. This excursion may reflect the variation of a large nondipole source near Hawaii.

Interactions between Lactobacillus kefiranofaciens and Saccharomyces cerevisiae in mixed culture for kefiran production.

PubMed

Cheirsilp, Benjamas; Shoji, Hirofumi; Shimizu, Hiroshi; Shioya, Suteaki

2003-01-01

Since a positive effect on the growth and kefiran production of Lactobacillus kefiranofaciens was observed in a mixed culture with Saccharomyces cerevisiae, the elucidation of the interactions between L. kefiranofaciens and S. cerevisiae may lead to higher productivity. Hence, the microbial interaction of each strain was investigated. Apart from the positive effect of a reduction in the amount of lactic acid by S. cerevisiae, a positive effect of S. cerevisiae on the growth and kefiran production of L. kefiranofaciens in a mixed culture was observed. Various experiments were carried out to study this effect. In this study, the observed increase in capsular kefiran in a mixed culture with inactivated S. cerevisiae correlated well to that in an anaerobic mixed culture. Differences in capsular kefiran production were observed for different initial S. cerevisiae concentrations under anaerobic conditions. From these fermentation results, it was concluded that the physical contact with S. cerevisiae mainly enhanced the capsular kefiran production of L. kefiranofaciens in a mixed culture. Therefore, in an anaerobic mixed culture, this direct contact resulted in higher capsular kefiran production than that in pure culture.

Cold-nuclear-matter effects on heavy-quark production at forward and backward rapidity in d + Au collisions at √sNN = 200  GeV.

PubMed

Adare, A; Aidala, C; Ajitanand, N N; Akiba, Y; Akimoto, R; Al-Bataineh, H; Al-Ta'ani, H; Alexander, J; Andrews, K R; Angerami, A; Aoki, K; Apadula, N; Appelt, E; Aramaki, Y; Armendariz, R; Aschenauer, E C; Atomssa, E T; Averbeck, R; Awes, T C; Azmoun, B; Babintsev, V; Bai, M; Baksay, G; Baksay, L; Bannier, B; Barish, K N; Bassalleck, B; Basye, A T; Bathe, S; Baublis, V; Baumann, C; Bazilevsky, A; Belikov, S; Belmont, R; Ben-Benjamin, J; Bennett, R; Bhom, J H; Blau, D S; Bok, J S; Boyle, K; Brooks, M L; Broxmeyer, D; Buesching, H; Bumazhnov, V; Bunce, G; Butsyk, S; Campbell, S; Caringi, A; Castera, P; Chen, C-H; Chi, C Y; Chiu, M; Choi, I J; Choi, J B; Choudhury, R K; Christiansen, P; Chujo, T; Chung, P; Chvala, O; Cianciolo, V; Citron, Z; Cole, B A; Conesa Del Valle, Z; Connors, M; Csanád, M; Csörgő, T; Dahms, T; Dairaku, S; Danchev, I; Das, K; Datta, A; David, G; Dayananda, M K; Denisov, A; Deshpande, A; Desmond, E J; Dharmawardane, K V; Dietzsch, O; Dion, A; Donadelli, M; Drapier, O; Drees, A; Drees, K A; Durham, J M; Durum, A; Dutta, D; D'Orazio, L; Edwards, S; Efremenko, Y V; Ellinghaus, F; Engelmore, T; Enokizono, A; En'yo, H; Esumi, S; Fadem, B; Fields, D E; Finger, M; Finger, M; Fleuret, F; Fokin, S L; Fraenkel, Z; Frantz, J E; Franz, A; Frawley, A D; Fujiwara, K; Fukao, Y; Fusayasu, T; Gal, C; Garishvili, I; Glenn, A; Gong, H; Gong, X; Gonin, M; Goto, Y; Granier de Cassagnac, R; Grau, N; Greene, S V; Grim, G; Grosse Perdekamp, M; Gunji, T; Guo, L; Gustafsson, H-Å; Haggerty, J S; Hahn, K I; Hamagaki, H; Hamblen, J; Han, R; Hanks, J; Harper, C; Hashimoto, K; Haslum, E; Hayano, R; He, X; Heffner, M; Hemmick, T K; Hester, T; Hill, J C; Hohlmann, M; Hollis, R S; Holzmann, W; Homma, K; Hong, B; Horaguchi, T; Hori, Y; Hornback, D; Huang, S; Ichihara, T; Ichimiya, R; Iinuma, H; Ikeda, Y; Imai, K; Inaba, M; Iordanova, A; Isenhower, D; Ishihara, M; Issah, M; Ivanischev, D; Iwanaga, Y; Jacak, B V; Jia, J; Jiang, X; Jin, J; John, D; Johnson, B M; Jones, T; Joo, K S; Jouan, D; Jumper, D S; Kajihara, F; Kamin, J; Kaneti, S; Kang, B H; Kang, J H; Kang, J S; Kapustinsky, J; Karatsu, K; Kasai, M; Kawall, D; Kawashima, M; Kazantsev, A V; Kempel, T; Khanzadeev, A; Kijima, K M; Kikuchi, J; Kim, A; Kim, B I; Kim, D J; Kim, E-J; Kim, Y-J; Kim, Y K; Kinney, E; Kiss, A; Kistenev, E; Kleinjan, D; Kline, P; Kochenda, L; Komkov, B; Konno, M; Koster, J; Kotov, D; Král, A; Kravitz, A; Kunde, G J; Kurita, K; Kurosawa, M; Kwon, Y; Kyle, G S; Lacey, R; Lai, Y S; Lajoie, J G; Lebedev, A; Lee, D M; Lee, J; Lee, K B; Lee, K S; Lee, S H; Lee, S R; Leitch, M J; Leite, M A L; Li, X; Lichtenwalner, P; Liebing, P; Lim, S H; Linden Levy, L A; Liška, T; Liu, H; Liu, M X; Love, B; Lynch, D; Maguire, C F; Makdisi, Y I; Malik, M D; Manion, A; Manko, V I; Mannel, E; Mao, Y; Masui, H; Matathias, F; McCumber, M; McGaughey, P L; McGlinchey, D; McKinney, C; Means, N; Mendoza, M; Meredith, B; Miake, Y; Mibe, T; Mignerey, A C; Miki, K; Milov, A; Mitchell, J T; Miyachi, Y; Mohanty, A K; Moon, H J; Morino, Y; Morreale, A; Morrison, D P; Motschwiller, S; Moukhanova, T V; Murakami, T; Murata, J; Nagamiya, S; Nagle, J L; Naglis, M; Nagy, M I; Nakagawa, I; Nakamiya, Y; Nakamura, K R; Nakamura, T; Nakano, K; Nam, S; Newby, J; Nguyen, M; Nihashi, M; Nouicer, R; Nyanin, A S; Oakley, C; O'Brien, E; Oda, S X; Ogilvie, C A; Oka, M; Okada, K; Onuki, Y; Oskarsson, A; Ouchida, M; Ozawa, K; Pak, R; Pantuev, V; Papavassiliou, V; Park, B H; Park, I H; Park, S K; Park, W J; Pate, S F; Patel, L; Pei, H; Peng, J-C; Pereira, H; Peressounko, D Yu; Petti, R; Pinkenburg, C; Pisani, R P; Proissl, M; Purschke, M L; Qu, H; Rak, J; Ravinovich, I; Read, K F; Rembeczki, S; Reygers, K; Riabov, V; Riabov, Y; Richardson, E; Roach, D; Roche, G; Rolnick, S D; Rosati, M; Rosen, C A; Rosendahl, S S E; Ružička, P; Sahlmueller, B; Saito, N; Sakaguchi, T; Sakashita, K; Samsonov, V; Sano, S; Sarsour, M; Sato, T; Savastio, M; Sawada, S; Sedgwick, K; Seele, J; Seidl, R; Seto, R; Sharma, D; Shein, I; Shibata, T-A; Shigaki, K; Shim, H H; Shimomura, M; Shoji, K; Shukla, P; Sickles, A; Silva, C L; Silvermyr, D; Silvestre, C; Sim, K S; Singh, B K; Singh, C P; Singh, V; Slunečka, M; Sodre, T; Soltz, R A; Sondheim, W E; Sorensen, S P; Sourikova, I V; Stankus, P W; Stenlund, E; Stoll, S P; Sugitate, T; Sukhanov, A; Sun, J; Sziklai, J; Takagui, E M; Takahara, A; Taketani, A; Tanabe, R; Tanaka, Y; Taneja, S; Tanida, K; Tannenbaum, M J; Tarafdar, S; Taranenko, A; Tennant, E; Themann, H; Thomas, D; Thomas, T L; Togawa, M; Toia, A; Tomášek, L; Tomášek, M; Torii, H; Towell, R S; Tserruya, I; Tsuchimoto, Y; Utsunomiya, K; Vale, C; Valle, H; van Hecke, H W; Vazquez-Zambrano, E; Veicht, A; Velkovska, J; Vértesi, R; Virius, M; Vossen, A; Vrba, V; Vznuzdaev, E; Wang, X R; Watanabe, D; Watanabe, K; Watanabe, Y; Watanabe, Y S; Wei, F; Wei, R; Wessels, J; White, S N; Winter, D; Woody, C L; Wright, R M; Wysocki, M; Yamaguchi, Y L; Yamaura, K; Yang, R; Yanovich, A; Ying, J; Yokkaichi, S; Yoo, J S; You, Z; Young, G R; Younus, I; Yushmanov, I E; Zajc, W A; Zelenski, A; Zhou, S

2014-06-27

The PHENIX experiment has measured open heavy-flavor production via semileptonic decay over the transverse momentum range 1 < p(T) < 6  GeV/c at forward and backward rapidity (1.4 < |y| < 2.0) in d+Au and p + p collisions at √sNN = 200  GeV. In central d+Au collisions, relative to the yield in p + p collisions scaled by the number of binary nucleon-nucleon collisions, a suppression is observed at forward rapidity (in the d-going direction) and an enhancement at backward rapidity (in the Au-going direction). Predictions using nuclear-modified-parton-distribution functions, even with additional nuclear-p(T) broadening, cannot simultaneously reproduce the data at both rapidity ranges, which implies that these models are incomplete and suggests the possible importance of final-state interactions in the asymmetric d + Au collision system. These results can be used to probe cold-nuclear-matter effects, which may significantly affect heavy-quark production, in addition to helping constrain the magnitude of charmonia-breakup effects in nuclear matter.

Study of the dependence of direct soft photon production on the jet characteristics in hadronic Z 0 decays

NASA Astrophysics Data System (ADS)

Abdallah, J.; Abreu, P.; Adam, W.; Adzic, P.; Albrecht, T.; Alemany-Fernandez, R.; Allmendinger, T.; Allport, P. P.; Amaldi, U.; Amapane, N.; Amato, S.; Anashkin, E.; Andreazza, A.; Andringa, S.; Anjos, N.; Antilogus, P.; Apel, W.-D.; Arnoud, Y.; Ask, S.; Asman, B.; Augustin, J. E.; Augustinus, A.; Baillon, P.; Ballestrero, A.; Bambade, P.; Barbier, R.; Bardin, D.; Barker, G. J.; Baroncelli, A.; Battaglia, M.; Baubillier, M.; Becks, K.-H.; Begalli, M.; Behrmann, A.; Ben-Haim, E.; Benekos, N.; Benvenuti, A.; Berat, C.; Berggren, M.; Bertrand, D.; Besancon, M.; Besson, N.; Bloch, D.; Blom, M.; Bluj, M.; Bonesini, M.; Boonekamp, M.; Booth, P. S. L.; Borisov, G.; Botner, O.; Bouquet, B.; Bowcock, T. J. V.; Boyko, I.; Bracko, M.; Brenner, R.; Brodet, E.; Bruckman, P.; Brunet, J. M.; Buschbeck, B.; Buschmann, P.; Calvi, M.; Camporesi, T.; Canale, V.; Carena, F.; Castro, N.; Cavallo, F.; Chapkin, M.; Charpentier, Ph.; Checchia, P.; Chierici, R.; Chliapnikov, P.; Chudoba, J.; Chung, S. U.; Cieslik, K.; Collins, P.; Contri, R.; Cosme, G.; Cossutti, F.; Costa, M. J.; Crennell, D.; Cuevas, J.; D'Hondt, J.; da Silva, T.; da Silva, W.; Della Ricca, G.; de Angelis, A.; de Boer, W.; de Clercq, C.; de Lotto, B.; de Maria, N.; de Min, A.; de Paula, L.; di Ciaccio, L.; di Simone, A.; Doroba, K.; Drees, J.; Eigen, G.; Ekelof, T.; Ellert, M.; Elsing, M.; Espirito Santo, M. C.; Fanourakis, G.; Fassouliotis, D.; Feindt, M.; Fernandez, J.; Ferrer, A.; Ferro, F.; Flagmeyer, U.; Foeth, H.; Fokitis, E.; Fulda-Quenzer, F.; Fuster, J.; Gandelman, M.; Garcia, C.; Gavillet, Ph.; Gazis, E.; Gokieli, R.; Golob, B.; Gomez-Ceballos, G.; Goncalves, P.; Graziani, E.; Grosdidier, G.; Grzelak, K.; Guy, J.; Haag, C.; Hallgren, A.; Hamacher, K.; Hamilton, K.; Haug, S.; Hauler, F.; Hedberg, V.; Hennecke, M.; Hoffman, J.; Holmgren, S.-O.; Holt, P. J.; Houlden, M. A.; Jackson, J. N.; Jarlskog, G.; Jarry, P.; Jeans, D.; Johansson, E. K.; Jonsson, P.; Joram, C.; Jungermann, L.; Kapusta, F.; Katsanevas, S.; Katsoufis, E.; Kernel, G.; Kersevan, B. P.; Kerzel, U.; King, B. T.; Kjaer, N. J.; Kluit, P.; Kokkinias, P.; Kourkoumelis, C.; Kouznetsov, O.; Krumstein, Z.; Kucharczyk, M.; Lamsa, J.; Leder, G.; Ledroit, F.; Leinonen, L.; Leitner, R.; Lemonne, J.; Lepeltier, V.; Lesiak, T.; Liebig, W.; Liko, D.; Lipniacka, A.; Lopes, J. H.; Lopez, J. M.; Loukas, D.; Lutz, P.; Lyons, L.; MacNaughton, J.; Malek, A.; Maltezos, S.; Mandl, F.; Marco, J.; Marco, R.; Marechal, B.; Margoni, M.; Marin, J.-C.; Mariotti, C.; Markou, A.; Martinez-Rivero, C.; Masik, J.; Mastroyiannopoulos, N.; Matorras, F.; Matteuzzi, C.; Mazzucato, F.; Mazzucato, M.; Mc Nulty, R.; Meroni, C.; Migliore, E.; Mitaroff, W.; Mjoernmark, U.; Moa, T.; Moch, M.; Moenig, K.; Monge, R.; Montenegro, J.; Moraes, D.; Moreno, S.; Morettini, P.; Mueller, U.; Muenich, K.; Mulders, M.; Mundim, L.; Murray, W.; Muryn, B.; Myatt, G.; Myklebust, T.; Nassiakou, M.; Navarria, F.; Nawrocki, K.; Nemecek, S.; Nicolaidou, R.; Nikolenko, M.; Oblakowska-Mucha, A.; Obraztsov, V.; Olshevski, A.; Onofre, A.; Orava, R.; Osterberg, K.; Ouraou, A.; Oyanguren, A.; Paganoni, M.; Paiano, S.; Palacios, J. P.; Palka, H.; Papadopoulou, Th. D.; Pape, L.; Parkes, C.; Parodi, F.; Parzefall, U.; Passeri, A.; Passon, O.; Peralta, L.; Perepelitsa, V.; Perrotta, A.; Petrolini, A.; Piedra, J.; Pieri, L.; Pierre, F.; Pimenta, M.; Piotto, E.; Podobnik, T.; Poireau, V.; Pol, M. E.; Polok, G.; Pozdniakov, V.; Pukhaeva, N.; Pullia, A.; Radojicic, D.; Rebecchi, P.; Rehn, J.; Reid, D.; Reinhardt, R.; Renton, P.; Richard, F.; Ridky, J.; Rivero, M.; Rodriguez, D.; Romero, A.; Ronchese, P.; Roudeau, P.; Rovelli, T.; Ruhlmann-Kleider, V.; Ryabtchikov, D.; Sadovsky, A.; Salmi, L.; Salt, J.; Sander, C.; Savoy-Navarro, A.; Schwickerath, U.; Sekulin, R.; Siebel, M.; Sisakian, A.; Smadja, G.; Smirnova, O.; Sokolov, A.; Sopczak, A.; Sosnowski, R.; Spassov, T.; Stanitzki, M.; Stocchi, A.; Strauss, J.; Stugu, B.; Szczekowski, M.; Szeptycka, M.; Szumlak, T.; Tabarelli, T.; Tegenfeldt, F.; Timmermans, J.; Tkatchev, L.; Tobin, M.; Todorovova, S.; Tome, B.; Tonazzo, A.; Tortosa, P.; Travnicek, P.; Treille, D.; Tristram, G.; Trochimczuk, M.; Troncon, C.; Turluer, M.-L.; Tyapkin, I. A.; Tyapkin, P.; Tzamarias, S.; Uvarov, V.; Valenti, G.; van Dam, P.; van Eldik, J.; van Remortel, N.; van Vulpen, I.; Vegni, G.; Veloso, F.; Venus, W.; Verdier, P.; Verzi, V.; Vilanova, D.; Vitale, L.; Vrba, V.; Wahlen, H.; Washbrook, A. J.; Weiser, C.; Wicke, D.; Wickens, J.; Wilkinson, G.; Winter, M.; Witek, M.; Yushchenko, O.; Zalewska, A.; Zalewski, P.; Zavrtanik, D.; Zhuravlov, V.; Zimin, N. I.; Zintchenko, A.; Zupan, M.; DELPHI Collaboration

2010-06-01

An analysis of the direct soft photon production rate as a function of the parent jet characteristics is presented, based on hadronic events collected by the DELPHI experiment at LEP1. The dependences of the photon rates on the jet kinematic characteristics (momentum, mass, etc.) and on the jet charged, neutral and total hadron multiplicities are reported. Up to a scale factor of about four, which characterizes the overall value of the soft photon excess, a similarity of the observed soft photon behavior to that of the inner hadronic bremsstrahlung predictions is found for the momentum, mass, and jet charged multiplicity dependences. However for the dependence of the soft photon rate on the jet neutral and total hadron multiplicities a prominent difference is found for the observed soft photon signal as compared to the expected bremsstrahlung from final state hadrons. The observed linear increase of the soft photon production rate with the jet total hadron multiplicity and its strong dependence on the jet neutral multiplicity suggest that the rate is proportional to the number of quark pairs produced in the fragmentation process, with the neutral pairs being more effectively radiating than the charged ones.

Assessment of Direct-to-Consumer Genetic Testing Policy in Korea Based on Consumer Preference.

PubMed

Jeong, Gicheol

2017-01-01

In June 2016, Korea permitted direct-to-consumer genetic testing (DTC-GT) on 42 genes. However, both the market and industry have not yet been fully activated. Considering the aforementioned context, this study provides important insights. The Korean DTC-GT policy assessment is based on consumer preference analysis using a discrete choice experiment. In August 2016, a web-based survey was conducted to collect data from 1,200 respondents. The estimation results show that consumers prefer a DTC-GT product that is cheap, tests various items or genes, offers accurate test results, and guarantees the confidentiality of all information. However, consumers are not entirely satisfied by current DTC-GT products due to the existence of insufficient and/or inadequate policies. First, the permitted testing of 42 genes is insufficient to satisfy consumers' curiosity regarding their genes. Second, the accuracy of the DTC-GT products has not been fully verified, assessed, and communicated to consumers. Finally, regulatory loopholes that allow information leaks in the DTC-GT process can occur. These findings imply that DTC-GT requires an improvement in government policy-making criteria and the implementation of practical measures to guarantee test accuracy and genetic information. © 2017 S. Karger AG, Basel.

Virtual manufacturing in reality

NASA Astrophysics Data System (ADS)

Papstel, Jyri; Saks, Alo

2000-10-01

SMEs play an important role in manufacturing industry. But from time to time there is a shortage in resources to complete the particular order in time. Number of systems is introduced to produce digital information in order to support product and process development activities. Main problem is lack of opportunity for direct data transition within design system modules when needed temporary extension of design capacity (virtuality) or to implement integrated concurrent product development principles. The planning experience in the field is weakly used as well. The concept of virtual manufacturing is a supporting idea to solve this problem. At the same time a number of practical problems should be solved like information conformity, data transfer, unified technological concepts acceptation etc. In the present paper the proposed ways to solve the practical problems of virtual manufacturing are described. General objective is to introduce the knowledge-based CAPP system as missing module for Virtual Manufacturing in the selected product domain. Surface-centered planning concept based on STEP- based modeling principles, and knowledge-based process planning methodology will be used to gain the objectives. As a result the planning module supplied by design data with direct access, and supporting advising environment is expected. Mould producing SME would be as test basis.

Reconfigurable manufacturing systems: Principles, design, and future trends

NASA Astrophysics Data System (ADS)

Koren, Yoram; Gu, Xi; Guo, Weihong

2018-06-01

Reconfigurable manufacturing systems (RMSs), which possess the advantages of both dedicated serial lines and flexible manufacturing systems, were introduced in the mid-1990s to address the challenges initiated by globalization. The principal goal of an RMS is to enhance the responsiveness of manufacturing systems to unforeseen changes in product demand. RMSs are costeffective because they boost productivity, and increase the lifetime of the manufacturing system. Because of the many streams in which a product may be produced on an RMS, maintaining product precision in an RMS is a challenge. But the experience with RMS in the last 20 years indicates that product quality can be definitely maintained by inserting in-line inspection stations. In this paper, we formulate the design and operational principles for RMSs, and provide a state-of-the-art review of the design and operations methodologies of RMSs according to these principles. Finally, we propose future research directions, and deliberate on how recent intelligent manufacturing technologies may advance the design and operations of RMSs.

Process Modeling of Composite Materials for Wind-Turbine Rotor Blades: Experiments and Numerical Modeling

PubMed Central

Wieland, Birgit; Ropte, Sven

2017-01-01

The production of rotor blades for wind turbines is still a predominantly manual process. Process simulation is an adequate way of improving blade quality without a significant increase in production costs. This paper introduces a module for tolerance simulation for rotor-blade production processes. The investigation focuses on the simulation of temperature distribution for one-sided, self-heated tooling and thick laminates. Experimental data from rotor-blade production and down-scaled laboratory tests are presented. Based on influencing factors that are identified, a physical model is created and implemented as a simulation. This provides an opportunity to simulate temperature and cure-degree distribution for two-dimensional cross sections. The aim of this simulation is to support production processes. Hence, it is modelled as an in situ simulation with direct input of temperature data and real-time capability. A monolithic part of the rotor blade, the main girder, is used as an example for presenting the results. PMID:28981458

Process Modeling of Composite Materials for Wind-Turbine Rotor Blades: Experiments and Numerical Modeling.

PubMed

Wieland, Birgit; Ropte, Sven

2017-10-05

The production of rotor blades for wind turbines is still a predominantly manual process. Process simulation is an adequate way of improving blade quality without a significant increase in production costs. This paper introduces a module for tolerance simulation for rotor-blade production processes. The investigation focuses on the simulation of temperature distribution for one-sided, self-heated tooling and thick laminates. Experimental data from rotor-blade production and down-scaled laboratory tests are presented. Based on influencing factors that are identified, a physical model is created and implemented as a simulation. This provides an opportunity to simulate temperature and cure-degree distribution for two-dimensional cross sections. The aim of this simulation is to support production processes. Hence, it is modelled as an in situ simulation with direct input of temperature data and real-time capability. A monolithic part of the rotor blade, the main girder, is used as an example for presenting the results.

From e+e- to Heavy Ion Collisions - Proceedings of the XXX International Symposium on Multiparticle Dynamics

NASA Astrophysics Data System (ADS)

Csörgő, Tamás Hegyi, Sándor Kittel, Wolfram

The Table of Contents for the book is as follows: * Preface * QCD IN MULTIPARTICLE PRODUCTION * QCD and multiparticle production - The status of the perturbative cascade * Test of QCD predictions for multiparticle production at LEP * Multijet final states in e+e- annihilation * Tests of QCD in two photon physics at LEP * Interplay between perturbative and non-perturbative QCD in three-jet events * QCD and hadronic final states at the LHC * Transverse energy and minijets in high energy collisions * Multiparticle production at RHIC and LHC: A classical point of view * High energy interaction with the nucleus in the perturbative QCD with Nc → ∞ * DIFFRACTIVE PRODUCTION AND SMALL-x * Introduction to low-x physics and diffraction * Low-x physics at HERA * Diffractive structure functions at the Tevatron * What is the experimental evidence for the BFKL Pomeron? * Self-organized criticality in gluon systems and its consequences * Scale anomaly and dipole scattering in QCD * Pomeron and AdS/CFT correspondence for QCD * INTERPLAY BETWEEN SOFT AND HARD PHENOMENA * Inclusive jet cross sections and BFKL dynamics searches in dijet cross sections * Soft and hard interactions in p bar{p} Collisions at √ s = 1800 and 630 GeV * Recent results on particle production from OPAL * New results on αs and optimized scales * Preliminary results of the standard model Higgs boson search at LEP 2 in 2000 * Ways to go between hard and soft QCD * Alternative scenarios for fragmentation of a gluonic Lund String * A simultaneous measurement of the QCD colour charges and the strong coupling from LEP multijet data * Branching processes and Koenigs function * Soft and hard QCD dynamics in J/ψ hadroproduction * HADRONIC FINAL STATES IN 1+1, 1+h AND h+h REACTIONS * Universality in hadron production in electron-positron, lepton-hadron and hadron-hadron reactions * Search for gluonic mesons in gluon jets * Vector-to-pseudoscalar and meson-to-baryon ratios in hadronic Z decays at LEP * Polarization and spin alignment in multihadronic Z0 decays * Jet physics at HERA * Final state studies at HERA * A gauge-invariant subtraction technique for non-inclusive observables in QCD * Baryon transport in dual models and the possibility of a backward peak in diffraction * ASTROPARTICLE PHYSICS * Cosmic rays in the energy range of the knee - Recent results from KASCADE * Imaging atmospheric Čerenkov telescopes: Techniques and results * Extensive air shower simulations with CORSIKA and the influence of high-energy hadronic interaction models * Future directions in astroparticle physics and the AUGER experiment * p+A COLLISIONS * pp and pA collisions at CERN SPS * Charmonium attenuation and the quark-gluon plasma * Gluon depletion and J/ψ suppression in pA collisions * CORRELATIONS AND FLUCTUATIONS - EXPERIMENT * Experimental correlation analysis: Foundations and practice * Intermittency and correlations at LEP and at HERA * Moments of the charged-particle multiplicity distribution in Z decays at LEP * On the scale of visible jets in high energy electron-positron collisions * HBT in relativistic heavy ion collisions * Comparison of the pion emission function in hadron-hadron and heavy ion collisions * Multiparticle correlations at LEP1 * Inter-W Bose-Einstein correlations ellipse ... or not? * Colour reconnection at LEP2 * CORRELATIONS AND FLUCTUATIONS - THEORY * Correlations and fluctuations - introduction * Coherence and incoherence in Bose-Einstein correlations * Bose-Einstein correlations in cascade processes and non-extensive statistics * A systematic approach to anomalous phenomena at high energies * Reconstruction of hadronization stage in Pb+Pb collisions at 158A GeV/c * Status of ring-like correlations and wavelets * Fluctuation probes of quark deconfinement * PQCD structure and hadronization in jets and heavy-ion collisions * Net-baryon fluctuations at the QCD critical point * Fractional Fokker-Planck equation in time variable and oscillation of cumulant moments * QCD and multiplicity scaling * RELATIVISTIC HEAVY ION COLLISIONS - EXPERIMENT * Introduction to multiparticle dynamics at RHIC * First results from the STAR experiment at RHIC * Preliminary results from the PHENIX experiment at RHIC * Forward energy and multiplicity in Au-Au reactions at √ {s_{nn} } = 130{text{GeV}} * Results from the PHOBOS experiment on Au+Au collisions at RHIC * Strangeness production in Pb-Pb collisions at the CERN SPS: Results from the WA97 experiment * Direct photon production in 158A GeV 208Pb+208Pb collisions * Search for critical phenomena in Pb+Pb collisions * Recent NA49 results on Pb+Pb collisions at CERN SPS * J/ψ suppression in Pb+Pb collisions at CERN SPS * RELATIVISTIC HEAVY ION COLLISIONS - THEORY * Hyperon ratios at RHIC and the coalescence predictions at mid-rapidity * Dynamics of nuclear collisions and the dependence of the onset of anomalous J/ψ suppression on nucleon numbers of colliding nuclei * Multi-boson effects in Bose-Einstein interferometry * The source of the "third flow component" * Collective flow and multiparticle azimuthal correlations * Microscopic strangeness enhancement mechanisms at the SPS * Jet quenching at finite opacity and its application at RHIC energy * Particle rapidity density and collective phenomena in heavy ion collisions * Elliptic flow from an on-shell parton cascade * Dilepton production in ultrarelativistic heavy ion collisions * Coulomb and core/halo corrections to Bose-Einstein n-particle correlations * CP VIOLATION IN MULTIPARTICLE DYNAMICS * New results from NA48 experiment on neutral kaon rare decays * Measurement of direct CP violation by the NA48 experiment at CERN * Aspects of parity, CP, and time reversal violation in hot QCD * Decay of parity odd bubbles * Parity and time reversal studies at RHIC * Constraining CP-violating TGCS and measuring W-polarization at OPAL * Buckyballs of QCD: Gluon junction networks * List of participants

Mapping land cover from satellite images: A basic, low cost approach

NASA Technical Reports Server (NTRS)

Elifrits, C. D.; Barney, T. W.; Barr, D. J.; Johannsen, C. J.

1978-01-01

Simple, inexpensive methodologies developed for mapping general land cover and land use categories from LANDSAT images are reported. One methodology, a stepwise, interpretive, direct tracing technique was developed through working with university students from different disciplines with no previous experience in satellite image interpretation. The technique results in maps that are very accurate in relation to actual land cover and relative to the small investment in skill, time, and money needed to produce the products.

Metabolic characterization of cultured mammalian cells by mass balance analysis, tracer labeling experiments and computer-aided simulations.

PubMed

Okahashi, Nobuyuki; Kohno, Susumu; Kitajima, Shunsuke; Matsuda, Fumio; Takahashi, Chiaki; Shimizu, Hiroshi

2015-12-01

Studying metabolic directions and flow rates in cultured mammalian cells can provide key information for understanding metabolic function in the fields of cancer research, drug discovery, stem cell biology, and antibody production. In this work, metabolic engineering methodologies including medium component analysis, (13)C-labeling experiments, and computer-aided simulation analysis were applied to characterize the metabolic phenotype of soft tissue sarcoma cells derived from p53-null mice. Cells were cultured in medium containing [1-(13)C] glutamine to assess the level of reductive glutamine metabolism via the reverse reaction of isocitrate dehydrogenase (IDH). The specific uptake and production rates of glucose, organic acids, and the 20 amino acids were determined by time-course analysis of cultured media. Gas chromatography-mass spectrometry analysis of the (13)C-labeling of citrate, succinate, fumarate, malate, and aspartate confirmed an isotopically steady state of the cultured cells. After removing the effect of naturally occurring isotopes, the direction of the IDH reaction was determined by computer-aided analysis. The results validated that metabolic engineering methodologies are applicable to soft tissue sarcoma cells derived from p53-null mice, and also demonstrated that reductive glutamine metabolism is active in p53-null soft tissue sarcoma cells under normoxia. Copyright © 2015 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Direct pore-scale reactive transport modelling of dynamic wettability changes induced by surface complexation

NASA Astrophysics Data System (ADS)

Maes, Julien; Geiger, Sebastian

2018-01-01

Laboratory experiments have shown that oil production from sandstone and carbonate reservoirs by waterflooding could be significantly increased by manipulating the composition of the injected water (e.g. by lowering the ionic strength). Recent studies suggest that a change of wettability induced by a change in surface charge is likely to be one of the driving mechanism of the so-called low-salinity effect. In this case, the potential increase of oil recovery during waterflooding at low ionic strength would be strongly impacted by the inter-relations between flow, transport and chemical reaction at the pore-scale. Hence, a new numerical model that includes two-phase flow, solute reactive transport and wettability alteration is implemented based on the Direct Numerical Simulation of the Navier-Stokes equations and surface complexation modelling. Our model is first used to match experimental results of oil droplet detachment from clay patches. We then study the effect of wettability change on the pore-scale displacement for simple 2D calcite micro-models and evaluate the impact of several parameters such as water composition and injected velocity. Finally, we repeat the simulation experiments on a larger and more complex pore geometry representing a carbonate rock. Our simulations highlight two different effects of low-salinity on oil production from carbonate rocks: a smaller number of oil clusters left in the pores after invasion, and a greater number of pores invaded.

Planar Two-Plasmon-Decay Experiments at Polar-Direct-Drive Ignition-Relevant Scale Lengths at the National Ignition Facility

NASA Astrophysics Data System (ADS)

Rosenberg, M. J.; Solodov, A. A.; Seka, W.; Myatt, J. F.; Regan, S. P.; Hohenberger, M.; Epstein, R.; Collins, T. J. B.; Turnbull, D. P.; Ralph, J. E.; Barrios, M. A.; Moody, J. D.

2015-11-01

Results from the first experiments at the National Ignition Facility (NIF) to probe two-plasmon -decay (TPD) hot-electron production at scale lengths relevant to polar-direct-drive (PDD) ignition are reported. The irradiation on one side of a planar CH foil generated a plasma at the quarter-critical surface with a predicted density gradient scale length of Ln ~ 600 μm , a measured electron temperature of Te ~ 3 . 5 to 4.0 keV, an overlapped laser intensity of I ~ 6 ×1014 W/cm2, and a predicted TPD threshold parameter of η ~ 4 . The hard x-ray spectrum and the Kα emission from a buried Mo layer were measured to infer the hot-electron temperature and the fraction of total laser energy converted to TPD hot electrons. Optical emission at ω/2 correlated with the time-dependent hard x-ray signal confirms that TPD is responsible for the hot-electron generation. The effect of laser beam angle of incidence on TPD hot-electron generation was assessed, and the data show that the beam angle of incidence did not have a strong effect. These results will be used to benchmark simulations of TPD hot-electron production at conditions relevant to PDD ignition-scale implosions. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

Direct experience while eating: Laboratory outcomes among individuals with eating disorders versus healthy controls.

PubMed

Elices, Matilde; Carmona, Cristina; Narváez, Vanessa; Seto, Victoria; Martin-Blanco, Ana; Pascual, Juan C; Soriano, José; Soler, Joaquim

2017-12-01

To compare individuals with eating disorders (EDs) to healthy controls (HCs) to assess for differences in direct engagement in the eating process. Participants (n=58) were asked to eat an orange slice. To assess the degree of direct engagement with the eating process, participants were asked to write down 10 thoughts about the experience of eating the orange slice. Next, the participants were instructed to classify the main focus of each thought as either experiential ("direct experience") or analytical ("thinking about"). A direct experience index (DEI) was computed by dividing the number of times that participants classified an experience as a "direct experience" (the numerator) by the total number of all observations (i.e., direct experience+thinking about). Participants also completed the Five Facet Mindfulness Questionnaire (FFMQ) and the Experiences Questionnaire (EQ) to assess mindfulness facets and decentering, respectively. Compared to controls, participants in the EDs group presented significantly lower levels of direct experience during the eating task (EDs group: mean=43.54, SD=29.64; HCs group: mean=66.17, SD=22.23, p=0.03). Participants in the EDs group also scored significantly lower on other mindfulness-related variables. These findings suggest that engagement with the direct experience of eating is lower in individuals with EDs. Future research should investigate the role of mindfulness-based interventions to address direct experience while eating in individuals with EDs. Copyright © 2017 Elsevier Ltd. All rights reserved.

Fixed target experiments at the Fermilab Tevatron

DOE PAGES

Gutierrez, Gaston; Reyes, Marco A.

2014-11-10

This paper presents a review of the study of Exclusive Central Production at a Center of Mass energy of √s = 40 GeV at the Fermilab Fixed Target program. In all reactions reviewed in this paper, protons with an energy of 800 GeV were extracted from the Tevatron accelerator at Fermilab and directed to a Liquid Hydrogen target. The states reviewed include π⁺π⁻, K⁰ s K⁰ s, K⁰ s K ±π ∓, φφ and D *±. Partial Wave Analysis results will be presented on the light states but only the cross-section will be reviewed in the diffractive production of Dmore » *±.« less

HIGGS H → γγ IN ASSOCIATION WITH Z/W BOSONS

NASA Astrophysics Data System (ADS)

Brelier, B.

2009-09-01

Electro-weak precision measurements strongly suggest that the mass of the Standard Model Higgs boson, if it exists, should not be much higher than the present experimental limit of 114.4 GeV/c2. The LHC experiments will allow us to look for a Higgs boson in this mass range for which the decay into photons is one of the most important channels. The isolation of events from Higgs boson production in association with Z/W bosons may increase the statistical significance of the Higgs boson discovery and these production modes can be used to measure directly the Higgs boson couplings to the weak bosons, thus helping to confirm the nature of the observed resonance.

State-to-state quantum dynamics of the F + HCl (vi = 0, ji = 0) → HF(vf, jf) + Cl reaction on the ground state potential energy surface.

PubMed

Li, Anyang; Guo, Hua; Sun, Zhigang; Kłos, Jacek; Alexander, Millard H

2013-10-07

The state-to-state reaction dynamics of the title reaction is investigated on the ground electronic state potential energy surface using two quantum dynamical methods. The results obtained using the Chebyshev real wave packet method are in excellent agreement with those obtained using the time-independent method, except at low translational energies. It is shown that this exothermic hydrogen abstraction reaction is direct, resulting in a strong back-scattered bias in the product angular distribution. The HF product is highly excited internally. Agreement with available experimental data is only qualitative. We discuss several possible causes of disagreement with experiment.

Aerogel mass production for the CLAS12 RICH: Novel characterization methods and optical performance

NASA Astrophysics Data System (ADS)

Contalbrigo, M.; Balossino, I.; Barion, L.; Barnyakov, A. Yu.; Battaglia, G.; Danilyuk, A. F.; Katcin, A. A.; Kravchenko, E. A.; Mirazita, M.; Movsisyan, A.; Orecchini, D.; Pappalardo, L. L.; Squerzanti, S.; Tomassini, S.; Turisini, M.

2017-12-01

A large area ring-imaging Cherenkov detector has been designed to provide clean hadron identification capabilities in the momentum range from 3 GeV/c to 8 GeV/c for the CLAS12 experiments at the Jefferson Lab upgraded 12 GeV continuous electron beam accelerator facility. The adopted solution foresees a novel hybrid optics design based on an aerogel radiator, composite mirrors and densely-packed and highly-segmented photon detectors. Cherenkov light will either be imaged directly (forward tracks) or after two mirror reflections (large angle tracks). The status of the aerogel mass-production and the assessment studies of the aerogel optical performance are here reported.

An Efficient Local Correlation Matrix Decomposition Approach for the Localization Implementation of Ensemble-Based Assimilation Methods

NASA Astrophysics Data System (ADS)

Zhang, Hongqin; Tian, Xiangjun

2018-04-01

Ensemble-based data assimilation methods often use the so-called localization scheme to improve the representation of the ensemble background error covariance (Be). Extensive research has been undertaken to reduce the computational cost of these methods by using the localized ensemble samples to localize Be by means of a direct decomposition of the local correlation matrix C. However, the computational costs of the direct decomposition of the local correlation matrix C are still extremely high due to its high dimension. In this paper, we propose an efficient local correlation matrix decomposition approach based on the concept of alternating directions. This approach is intended to avoid direct decomposition of the correlation matrix. Instead, we first decompose the correlation matrix into 1-D correlation matrices in the three coordinate directions, then construct their empirical orthogonal function decomposition at low resolution. This procedure is followed by the 1-D spline interpolation process to transform the above decompositions to the high-resolution grid. Finally, an efficient correlation matrix decomposition is achieved by computing the very similar Kronecker product. We conducted a series of comparison experiments to illustrate the validity and accuracy of the proposed local correlation matrix decomposition approach. The effectiveness of the proposed correlation matrix decomposition approach and its efficient localization implementation of the nonlinear least-squares four-dimensional variational assimilation are further demonstrated by several groups of numerical experiments based on the Advanced Research Weather Research and Forecasting model.

'Who's a good boy?!' Dogs prefer naturalistic dog-directed speech.

PubMed

Benjamin, Alex; Slocombe, Katie

2018-05-01

Infant-directed speech (IDS) is a special speech register thought to aid language acquisition and improve affiliation in human infants. Although IDS shares some of its properties with dog-directed speech (DDS), it is unclear whether the production of DDS is functional, or simply an overgeneralisation of IDS within Western cultures. One recent study found that, while puppies attended more to a script read with DDS compared with adult-directed speech (ADS), adult dogs displayed no preference. In contrast, using naturalistic speech and a more ecologically valid set-up, we found that adult dogs attended to and showed more affiliative behaviour towards a speaker of DDS than of ADS. To explore whether this preference for DDS was modulated by the dog-specific words typically used in DDS, the acoustic features (prosody) of DDS or a combination of the two, we conducted a second experiment. Here the stimuli from experiment 1 were produced with reversed prosody, meaning the prosody and content of ADS and DDS were mismatched. The results revealed no significant effect of speech type, or content, suggesting that it is maybe the combination of the acoustic properties and the dog-related content of DDS that modulates the preference shown for naturalistic DDS. Overall, the results of this study suggest that naturalistic DDS, comprising of both dog-directed prosody and dog-relevant content words, improves dogs' attention and may strengthen the affiliative bond between humans and their pets.

Emulsion chamber observations and interpretation (HE 3)

NASA Technical Reports Server (NTRS)

Shibata, M.

1986-01-01

Experimental results from Emulsion Chamber (EC) experiments at mountain altitudes or at higher levels using flying carriers are examined. The physical interest in this field is concentrated on the strong interaction at the very high energy region exceeding the accelerator energy, also on the primary cosmic ray intensity and its chemical composition. Those experiments which observed cosmic ray secondaries gave information on high energy interaction characteristics through the analyses of secondary spectra, gamma-hadron families and C-jets (direct observation of the particle production occuring at the carbon target). Problems of scaling violation in fragmentation region, interaction cross section, transverse momentum of produced secondaries, and some peculiar features of exotic events are discussed.

Kinetic mechanism of ATP-sulphurylase from rat chondrosarcoma.

PubMed Central

Lyle, S; Geller, D H; Ng, K; Westley, J; Schwartz, N B

1994-01-01

ATP-sulphurylase catalyses the production of adenosine 5'-phosphosulphate (APS) from ATP and free sulphate with the release of PPi. APS kinase phosphorylates the APS intermediate to produce adenosine 3'-phosphate 5'-phosphosulphate (PAPS). The kinetic mechanism of rat chondrosarcoma ATP-sulphurylase was investigated by steady-state methods in the physiologically forward direction as well as the reverse direction. The sulphurylase activity was coupled to APS kinase activity in order to overcome the thermodynamic constraints of the sulphurylase reaction in the forward direction. Double-reciprocal initial-velocity plots for the forward sulphurylase intersect to the left of the ordinate for this reaction. KmATP and Kmsulphate were found to be 200 and 97 microM respectively. Chlorate, a competitive inhibitor with respect to sulphate, showed uncompetitive inhibition with respect to ATP with an apparent Ki of 1.97 mM. Steady-state data from experiments in the physiologically reverse direction also yielded double-reciprocal initial-velocity patterns that intersect to the left of the ordinate axis, with a KmAPS of 39 microM and a Kmpyrophosphate of 18 microM. The results of steady-state experiments in which Mg2+ was varied indicated that the true substrate is the MgPPi complex. An analogue of APS, adenosine 5'-[beta-methylene]phosphosulphate, was a linear inhibitor competitive with APS and non-competitive with respect to MgPPi. The simplest formal mechanism that agrees with all the data is an ordered steady-state single displacement with MgATP as the leading substrate in the forward direction and APS as the leading substrate in the reverse direction. PMID:8042976

Public-private partnerships for health: their main targets, their diversity, and their future directions.

PubMed Central

Widdus, R.

2001-01-01

The global burden of disease, especially the part attributable to infectious diseases, disproportionately affects populations in developing countries. Inadequate access to pharmaceuticals plays a role in perpetuating this disparity. Drugs and vaccines may not be accessible because of weak distribution infrastructures or because development of the desired products has been neglected. This situation can be tackled with push interventions to lower the costs and risks of product development for industry, with pull interventions providing economic and market incentives, and with the creation of infrastructures allowing products to be put into use. If appropriately motivated, pharmaceutical companies can bring to partnerships expertise in product development, production process development, manufacturing, marketing, and distribution--all of which are lacking in the public sector. A large variety of public-private partnerships, combining the skills and resources of a wide range of collaborators, have arisen for product development, disease control through product donation and distribution, or the general strengthening or coordination of health services. Administratively, such partnerships may either involve affiliation with international organizations, i.e. they are essentially public-sector programmes with private-sector participation, or they may be legally independent not-for-profit bodies. These partnerships should be regarded as social experiments; they show promise but are not a panacea. New ventures should be built on need, appropriateness, and lessons on good practice learnt from experience. Suggestions are made for public, private, and joint activities that could help to improve the access of poor populations to the pharmaceuticals and health services they need. PMID:11545327

CLIPS: A proposal for improved usability

NASA Technical Reports Server (NTRS)

Patton, Charles R.

1990-01-01

This paper proposes the enhancement of the CLIPS user interface to improve the over-all usability of the CLIPS development environment. It suggests some directions for the long term growth of the user interface, and discusses some specific strengths and weaknesses of the current CLIPS PC user interface. Every user of CLIPS shares a common experience: his/her first interaction with the system itself. As with any new language, between the process of installing CLIPS on the appropriate computer and the completion of a large application, an intensive learning process takes place. For those with extensive programming knowledge and LISP backgrounds, this experience may have been mostly interesting and pleasant. Being familiar with products that are similar to CLIPS in many ways, these users enjoy a relatively short training period with the product. Already familiar with many of the functions they wish to employ, experienced users are free to focus on the capabilities of CLIPS that make it uniquely useful within their working environment.

Mushroom growing project at the Los Humeros, Mexico geothermal field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rangel, M.E.R.

1998-12-01

There are several projects of direct (non-electrical) use of geothermal energy in Mexico. Personnel of the Comision Federal de Electricidad (CFE) have experience in various of these projects, like drying of timber and fruits, space heating, food processing, etc. Taking this in consideration, CFE built the Los Humeros mushroom plant using for heat source the geothermal steam from Well H-1. The main purpose of the project was to take advantage of residual geothermal energy in a food production operation and to develop the appropriate technology. In 1992, existing installations were renovated, preparing appropriate areas for pasteurization, inoculation and production. Themore » mushroom Pleurotus ostreatus var. florida and columbinus was used. A year later, CFE proposed the construction of improved facilities for growing edible mushrooms. New materials and equipment, as well as different operation conditions, were proposed on the basis of the experience gained in the initial project. The construction and renovation activities were completed in 1994.« less

An evaluation of microorganisms for unconventional food regeneration schemes in CELSS - Research recommendations

NASA Technical Reports Server (NTRS)

Stokes, B. O.; Petersen, G. R.

1982-01-01

The benefits and deficiencies of various candidates for a controlled ecological life support system (CELSS) for manned spacecraft missions of at least 3-14 yr are discussed. Conventional plants are considered unacceptable due to their inefficient production of foodstuffs and overproduction of stems and leafy matter. The alternate concepts are algae and/or bacteria or chemical synthesis of food. Microorganisms are considered the most promising because of their direct use of CO2 and possible utilization of waste streams. Yeasts are cited as the most viable candidates, since a large data base and experience already exists in the commercial food industry. The addition of hydrogen bactria and solar-grown algae is recommended, together with genetic manipulation experiments to tailor the microorganisms to production of foodstuffs closer to the 70 percent carbohydrate, 20 percent protein, and 10 percent lipid optimal food currently accepted. The yeast strain, Hansenula polymorpha, has been successfully grown in methanol and encouraged to produce a 55 percent carbohydrate content.

The role of visual experience in the production of emotional facial expressions by blind people: a review.

PubMed

Valente, Dannyelle; Theurel, Anne; Gentaz, Edouard

2018-04-01

Facial expressions of emotion are nonverbal behaviors that allow us to interact efficiently in social life and respond to events affecting our welfare. This article reviews 21 studies, published between 1932 and 2015, examining the production of facial expressions of emotion by blind people. It particularly discusses the impact of visual experience on the development of this behavior from birth to adulthood. After a discussion of three methodological considerations, the review of studies reveals that blind subjects demonstrate differing capacities for producing spontaneous expressions and voluntarily posed expressions. Seventeen studies provided evidence that blind and sighted spontaneously produce the same pattern of facial expressions, even if some variations can be found, reflecting facial and body movements specific to blindness or differences in intensity and control of emotions in some specific contexts. This suggests that lack of visual experience seems to not have a major impact when this behavior is generated spontaneously in real emotional contexts. In contrast, eight studies examining voluntary expressions indicate that blind individuals have difficulty posing emotional expressions. The opportunity for prior visual observation seems to affect performance in this case. Finally, we discuss three new directions for research to provide additional and strong evidence for the debate regarding the innate or the culture-constant learning character of the production of emotional facial expressions by blind individuals: the link between perception and production of facial expressions, the impact of display rules in the absence of vision, and the role of other channels in expression of emotions in the context of blindness.

Study of the cosmogenic activation in NaI(Tl) crystals within the ANAIS experiment

NASA Astrophysics Data System (ADS)

Villar, P.; Amaré, J.; Cebrián, S.; Coarasa, I.; García, E.; Martínez, M.; Oliván, M. A.; Ortigoza, Y.; Ortiz de Solórzano, A.; Puimedón, J.; Sarsa, M. L.; Villar, J. A.

2018-03-01

The direct detection of galactic dark matter particles requires ultra-low background conditions. NaI(Tl) crystals are applied in the search for these dark matter particles through their interactions in the detector by measuring the scintillation signal produced. The production of long-lived isotopes in materials due to the exposure to cosmic rays on Earth’s surface can be an hazard for these ultra-low background demanding experiments, typically performed underground. Therefore, production rates of cosmogenic isotopes in all the materials present in the experimental set-up, as well as the corresponding cosmic rays exposure history, must be both well-known in order to assess the relevance of this effect in the achievable sensitivity of a given experiment. Here, analysis of the cosmogenic studies developed from the ANAIS experiment NaI(Tl) detectors are presented. Installed inside a convenient shielding at the Canfranc Underground Laboratory just after finishing surface exposure to cosmic rays and thanks to the prompt data taking developed, identification and quantification of isotopes with half-lives of the order of tens of days were allowed, and thanks to the long-term operation of the detectors long-lived isotopes have been also identified and quantified. Main results for the activation yields of iodine and tellurium isotopes, 22Na, 113Sn, 109Cd, and tritium are presented in this work, together with the estimate of the production rates for their activation by cosmic nucleons while on Earth’s surface based on a selection of excitation functions over the entire energy range of cosmic nucleons.

Alternative Fuels Research Laboratory

NASA Technical Reports Server (NTRS)

Surgenor, Angela D.; Klettlinger, Jennifer L.; Nakley, Leah M.; Yen, Chia H.

2012-01-01

NASA Glenn has invested over $1.5 million in engineering, and infrastructure upgrades to renovate an existing test facility at the NASA Glenn Research Center (GRC), which is now being used as an Alternative Fuels Laboratory. Facility systems have demonstrated reliability and consistency for continuous and safe operations in Fischer-Tropsch (F-T) synthesis and thermal stability testing. This effort is supported by the NASA Fundamental Aeronautics Subsonic Fixed Wing project. The purpose of this test facility is to conduct bench scale F-T catalyst screening experiments. These experiments require the use of a synthesis gas feedstock, which will enable the investigation of F-T reaction kinetics, product yields and hydrocarbon distributions. Currently the facility has the capability of performing three simultaneous reactor screening tests, along with a fourth fixed-bed reactor for catalyst activation studies. Product gas composition and performance data can be continuously obtained with an automated gas sampling system, which directly connects the reactors to a micro-gas chromatograph (micro GC). Liquid and molten product samples are collected intermittently and are analyzed by injecting as a diluted sample into designated gas chromatograph units. The test facility also has the capability of performing thermal stability experiments of alternative aviation fuels with the use of a Hot Liquid Process Simulator (HLPS) (Ref. 1) in accordance to ASTM D 3241 "Thermal Oxidation Stability of Aviation Fuels" (JFTOT method) (Ref. 2). An Ellipsometer will be used to study fuel fouling thicknesses on heated tubes from the HLPS experiments. A detailed overview of the test facility systems and capabilities are described in this paper.

An approach to the systematic analysis of urinary steroids

PubMed Central

Menini, E.; Norymberski, J. K.

1965-01-01

1. Human urine, its extracts, extracts of urine pretreated with enzyme preparations containing β-glucuronidase and steroid sulphatase or β-glucuronidase alone, and products derived from the specific solvolysis of urinary steroid sulphates, were submitted to the following sequence of operations: reduction with borohydride; oxidation with a glycol-cleaving agent (bismuthate or periodate); separation of the products into ketones and others; oxidation of each fraction with tert.-butyl chromate, resolution of the end products by means of paper chromatography or gas–liquid chromatography or both. 2. Qualitative experiments indicated the kind of information the method and some of its modifications can provide. Quantitative experiments were restricted to the direct treatment of urine by the basic procedure outlined. It was partly shown and partly argued that the quantitative results were probably as informative about the composition of the major neutral urinary steroids (and certainly about their presumptive secretory precursors) as those obtained by a number of established analytical procedures. 3. A possible extension of the scope of the reported method was indicated. 4. A simple technique was introduced for the quantitative deposition of a solid sample on to a gas–liquid-chromatographic column. PMID:14333557

Measurement of the forward-backward asymmetry of $$\\Lambda$$ and $$\\bar{\\Lambda}$$ production in $$p \\bar{p}$$ collisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abazov, Victor Mukhamedovich

Here, we studymore » $$\\Lambda$$ and $$\\bar{\\Lambda}$$ production asymmetries in $$p \\bar{p} \\rightarrow \\Lambda (\\bar{\\Lambda}) X$$, $$p \\bar{p} \\rightarrow J/\\psi \\Lambda (\\bar{\\Lambda}) X$$, and $$p \\bar{p} \\rightarrow \\mu^\\pm \\Lambda (\\bar{\\Lambda}) X$$ events recorded by the D0 detector at the Fermilab Tevatron collider at $$\\sqrt{s} = 1.96$$ TeV. We find an excess of $$\\Lambda$$'s ($$\\bar{\\Lambda}$$'s) produced in the proton (antiproton) direction. This forward-backward asymmetry is measured as a function of rapidity. We confirm that the $$\\bar{\\Lambda}/\\Lambda$$ production ratio, measured by several experiments with various targets and a wide range of energies, is a universal function of "rapidity loss", i.e., the rapidity difference of the beam proton and the lambda.« less

Measurement of the forward-backward asymmetry of $$\\Lambda$$ and $$\\bar{\\Lambda}$$ production in $$p \\bar{p}$$ collisions

DOE PAGES

Abazov, Victor Mukhamedovich

2016-02-09

Here, we studymore » $$\\Lambda$$ and $$\\bar{\\Lambda}$$ production asymmetries in $$p \\bar{p} \\rightarrow \\Lambda (\\bar{\\Lambda}) X$$, $$p \\bar{p} \\rightarrow J/\\psi \\Lambda (\\bar{\\Lambda}) X$$, and $$p \\bar{p} \\rightarrow \\mu^\\pm \\Lambda (\\bar{\\Lambda}) X$$ events recorded by the D0 detector at the Fermilab Tevatron collider at $$\\sqrt{s} = 1.96$$ TeV. We find an excess of $$\\Lambda$$'s ($$\\bar{\\Lambda}$$'s) produced in the proton (antiproton) direction. This forward-backward asymmetry is measured as a function of rapidity. We confirm that the $$\\bar{\\Lambda}/\\Lambda$$ production ratio, measured by several experiments with various targets and a wide range of energies, is a universal function of "rapidity loss", i.e., the rapidity difference of the beam proton and the lambda.« less

Production and delivery of polarized Xenon-129 for in vivo MRS/MRI.

NASA Astrophysics Data System (ADS)

Rosen, Matthew S.; Chupp, Timothy E.; Coulter, Kevin P.; Welsh, Robert C.; Swanson, Scott

1998-05-01

Laser polarized ^129Xe can be used as an entirely new magnetic tracer, and is a powerful enhancement to currently existing MRI techniques. Inert laser polarized ^129Xe is inhaled and transported via blood flow where it is detected using MR spectroscopy and imaging techniques. The time-dependent distribution patterns of ^129Xe signal intensity directly reflect local blood volume, blood flow rates, and the efficiency of perfusion and diffusive transport in tissues. We have developed a uniquely constructed laser polarized ^129Xe production and delivery system that is used in both our in vitro and in vivo imaging experiments with rats. This reliable, effective, and relatively simple production method for large volumes of laser polarized ^129Xe is the key to all other areas of research involving use of laser polarized gases.

Specificity and transfer effects in time production skill: examining the role of attention.

PubMed

Wohldmann, Erica L; Healy, Alice F; Bourne, Lyle E

2012-05-01

Two experiments examined transfer of a prospective, time production skill under conditions involving changes in concurrent task requirements. Positive transfer of the time production skill might be expected only when the attentional demands of the concurrent task were held constant from training to test. However, some positive transfer was found even when the concurrent task at retraining was made either easier or more difficult than the concurrent task learned during training. The amount and direction of transfer depended more on the pacing of the stimuli in the secondary task than on the difficulty of the secondary task, even though difficulty affects attentional demands more. These findings are consistent with the procedural reinstatement principle of skill learning, by which transfer from one task to another depends on an overlap in procedures required by the two skills.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharma, Ms. Ketki; Kim, Yong-Ha; Yiacoumi, Sotira

The mixing process of fresh water and seawater releases a significant amount of energy and is a potential source of renewable energy. The so called ‘blue energy’ or salinity-gradient energy can be harvested by a device consisting of carbon electrodes immersed in an electrolyte solution, based on the principle of capacitive double layer expansion (CDLE). In this study, we have investigated the feasibility of energy production based on the CDLE principle. Experiments and computer simulations were used to study the process. Mesoporous carbon materials, synthesized at the Oak Ridge National Laboratory, were used as electrode materials in the experiments. Neutronmore » imaging of the blue energy cycle was conducted with cylindrical mesoporous carbon electrodes and 0.5 M lithium chloride as the electrolyte solution. For experiments conducted at 0.6 V and 0.9 V applied potential, a voltage increase of 0.061 V and 0.054 V was observed, respectively. From sequences of neutron images obtained for each step of the blue energy cycle, information on the direction and magnitude of lithium ion transport was obtained. A computer code was developed to simulate the process. Experimental data and computer simulations allowed us to predict energy production.« less

Analysis and Simulation of a Blue Energy Cycle

DOE PAGES

Sharma, Ms. Ketki; Kim, Yong-Ha; Yiacoumi, Sotira; ...

2016-01-30

The mixing process of fresh water and seawater releases a significant amount of energy and is a potential source of renewable energy. The so called ‘blue energy’ or salinity-gradient energy can be harvested by a device consisting of carbon electrodes immersed in an electrolyte solution, based on the principle of capacitive double layer expansion (CDLE). In this study, we have investigated the feasibility of energy production based on the CDLE principle. Experiments and computer simulations were used to study the process. Mesoporous carbon materials, synthesized at the Oak Ridge National Laboratory, were used as electrode materials in the experiments. Neutronmore » imaging of the blue energy cycle was conducted with cylindrical mesoporous carbon electrodes and 0.5 M lithium chloride as the electrolyte solution. For experiments conducted at 0.6 V and 0.9 V applied potential, a voltage increase of 0.061 V and 0.054 V was observed, respectively. From sequences of neutron images obtained for each step of the blue energy cycle, information on the direction and magnitude of lithium ion transport was obtained. A computer code was developed to simulate the process. Experimental data and computer simulations allowed us to predict energy production.« less

An Updated Analysis of Direct-to-Consumer Television Advertisements for Prescription Drugs.

PubMed

Applequist, Janelle; Ball, Jennifer Gerard

2018-05-01

In 2015, the American Medical Association called for a ban of direct-to-consumer advertising (DTCA) for prescription drugs. Yet, the pharmaceutical industry spends more than ever on broadcast advertisements, with national health care costs largely driven by drug spending. An evaluation of these ads is critical, as these advertisements can impact the frequency which patients ask their doctors about medications. A content analysis of prime-time direct-to-consumer ads was conducted across 4 major cable television networks. The ad content (n = 61) was coded for factual claims made regarding target conditions, appeals used, portrayal of medications, and lifestyle characteristics shown. We found a substantial decrease in the percentage of ads that conveyed information about the conditions being targeted, such as risk factors (16%) and prevalence (16%). Positive emotional appeals (94%) continued to be emphasized; yet there was decreased use of negative emotional appeals (51%), pointing to an overall more positive portrayal of a patient's experience with a medication. The lifestyles portrayed in the sample largely featured how products can enable more recreational activities (69%) and fewer ads (7%) presented alternatives to product use. Direct-to-consumer advertising continued to promote prescription drugs above educating the population. Improvement in the educational value of DTCA is likely to require regulatory action rather than reliance on self-regulation by the pharmaceutical industry. © 2018 Annals of Family Medicine, Inc.

Gradient flux measurements of sea-air DMS transfer during the Surface Ocean Aerosol Production (SOAP) experiment

NASA Astrophysics Data System (ADS)

Smith, Murray J.; Walker, Carolyn F.; Bell, Thomas G.; Harvey, Mike J.; Saltzman, Eric S.; Law, Cliff S.

2018-04-01

Direct measurements of marine dimethylsulfide (DMS) fluxes are sparse, particularly in the Southern Ocean. The Surface Ocean Aerosol Production (SOAP) voyage in February-March 2012 examined the distribution and flux of DMS in a biologically active frontal system in the southwest Pacific Ocean. Three distinct phytoplankton blooms were studied with oceanic DMS concentrations as high as 25 nmol L-1. Measurements of DMS fluxes were made using two independent methods: the eddy covariance (EC) technique using atmospheric pressure chemical ionization-mass spectrometry (API-CIMS) and the gradient flux (GF) technique from an autonomous catamaran platform. Catamaran flux measurements are relatively unaffected by airflow distortion and are made close to the water surface, where gas gradients are largest. Flux measurements were complemented by near-surface hydrographic measurements to elucidate physical factors influencing DMS emission. Individual DMS fluxes derived by EC showed significant scatter and, at times, consistent departures from the Coupled Ocean-Atmosphere Response Experiment gas transfer algorithm (COAREG). A direct comparison between the two flux methods was carried out to separate instrumental effects from environmental effects and showed good agreement with a regression slope of 0.96 (r2 = 0.89). A period of abnormal downward atmospheric heat flux enhanced near-surface ocean stratification and reduced turbulent exchange, during which GF and EC transfer velocities showed good agreement but modelled COAREG values were significantly higher. The transfer velocity derived from near-surface ocean turbulence measurements on a spar buoy compared well with the COAREG model in general but showed less variation. This first direct comparison between EC and GF fluxes of DMS provides confidence in compilation of flux estimates from both techniques, as well as in the stable periods when the observations are not well predicted by the COAREG model.

SPACEHAB: A giant step in the commercial development of space

NASA Astrophysics Data System (ADS)

Shepard, James E.

SPACEHAB is a privately developed and operated system offering customers a crew-tended microgravity environment for experimentation and product development. The first SPACEHAB flight module was delivered to the SPACEHAB Payload Processing Facility (SPPF) in Florida and 22 experiments are being integrated for an April 1993 mission. SPACEHAB modules are flown in the forward quarter-bay of the NASA Orbiter and are supported by two crew members. The paylaod accommodations include up to 61 experiment lockers, double and single racks and standard mounting plates for mounting unique payload containers directly to the module structure. Experiments designed for the Orbiter mid-deck, Spacelab or Space Station Freedom can be flown in SPACEHAB. The 24-month integration cycle is currently the shortest for any crew-tended carrier; a goal of 18 months is being actively pursued.

Direct estimation of the permeation of topical excipients through artificial membranes and human skin with non-invasive Terahertz time-domain techniques.

PubMed

Lopez-Dominguez, Victor; Boix-Montañes, Antoni; Redo-Sanchez, Albert; Tejada-Palacios, Javier

2016-07-01

Drug permeation through skin, or a synthetic membrane, from locally acting pharmaceutical products can be influenced by the permeation behaviour of pharmaceutical excipients. Terahertz time-domain technology is investigated as a non-invasive method for a direct and accurate measurement of excipients permeation through synthetic membranes or human skin. A series of in-vitro release and skin permeation experiments of liquid excipients (e.g. propylene glycol and polyethylene glycol 400) has been conducted with vertical diffusion cells. The permeation profiles of excipients through different synthetic membranes or skin were obtained using Terahertz pulses providing a direct measurement. Corresponding permeation flux and permeability coefficient values were calculated based on temporal changes of the terahertz pulses. The influence of different experimental conditions, such as the polarity of the membrane and the viscosity of the permeant, was assessed in release experiments. Specific transmembrane flux values of those excipients were directly calculated with statistical differences between cases. Finally, an attempt to estimate the skin permeation of propylene glycol with this technique was also achieved. All these permeation results were likely comparable to those obtained by other authors with usual analytical techniques. Terahertz time-domain technology is shown to be a suitable technique for an accurate and non-destructive measurement of the permeation of liquid substances through different synthetic membranes or even human skin. © 2016 Royal Pharmaceutical Society.

Centrality dependence of low-momentum direct-photon production in Au +Au collisions at √{sN N}=200 GeV

NASA Astrophysics Data System (ADS)

Adare, A.; Afanasiev, S.; Aidala, C.; Ajitanand, N. N.; Akiba, Y.; Akimoto, R.; Al-Bataineh, H.; Al-Ta'Ani, H.; Alexander, J.; Angerami, A.; Aoki, K.; Apadula, N.; Aramaki, Y.; Asano, H.; Aschenauer, E. C.; Atomssa, E. T.; Averbeck, R.; Awes, T. C.; Azmoun, B.; Babintsev, V.; Bai, M.; Baksay, G.; Baksay, L.; Bannier, B.; Barish, K. N.; Bassalleck, B.; Basye, A. T.; Bathe, S.; Baublis, V.; Baumann, C.; Baumgart, S.; Bazilevsky, A.; Belikov, S.; Belmont, R.; Bennett, R.; Berdnikov, A.; Berdnikov, Y.; Bickley, A. A.; Bing, X.; Blau, D. S.; Bok, J. S.; Boyle, K.; Brooks, M. L.; Buesching, H.; Bumazhnov, V.; Bunce, G.; Butsyk, S.; Camacho, C. M.; Campbell, S.; Castera, P.; Chen, C.-H.; Chi, C. Y.; Chiu, M.; Choi, I. J.; Choi, J. B.; Choi, S.; Choudhury, R. K.; Christiansen, P.; Chujo, T.; Chung, P.; Chvala, O.; Cianciolo, V.; Citron, Z.; Cole, B. A.; Connors, M.; Constantin, P.; Csanád, M.; Csörgő, T.; Dahms, T.; Dairaku, S.; Danchev, I.; Das, K.; Datta, A.; Daugherity, M. S.; David, G.; Denisov, A.; Deshpande, A.; Desmond, E. J.; Dharmawardane, K. V.; Dietzsch, O.; Ding, L.; Dion, A.; Donadelli, M.; Drapier, O.; Drees, A.; Drees, K. A.; Durham, J. M.; Durum, A.; Dutta, D.; D'Orazio, L.; Edwards, S.; Efremenko, Y. V.; Ellinghaus, F.; Engelmore, T.; Enokizono, A.; En'yo, H.; Esumi, S.; Eyser, K. O.; Fadem, B.; Fields, D. E.; Finger, M.; Finger, M.; Fleuret, F.; Fokin, S. L.; Fraenkel, Z.; Frantz, J. E.; Franz, A.; Frawley, A. D.; Fujiwara, K.; Fukao, Y.; Fusayasu, T.; Gainey, K.; Gal, C.; Garishvili, A.; Garishvili, I.; Glenn, A.; Gong, H.; Gong, X.; Gonin, M.; Goto, Y.; Granier de Cassagnac, R.; Grau, N.; Greene, S. V.; Grosse Perdekamp, M.; Gunji, T.; Guo, L.; Gustafsson, H.-Å.; Hachiya, T.; Haggerty, J. S.; Hahn, K. I.; Hamagaki, H.; Hamblen, J.; Han, R.; Hanks, J.; Hartouni, E. P.; Hashimoto, K.; Haslum, E.; Hayano, R.; He, X.; Heffner, M.; Hemmick, T. K.; Hester, T.; Hill, J. C.; Hohlmann, M.; Hollis, R. S.; Holzmann, W.; Homma, K.; Hong, B.; Horaguchi, T.; Hori, Y.; Hornback, D.; Huang, S.; Ichihara, T.; Ichimiya, R.; Ide, J.; Iinuma, H.; Ikeda, Y.; Imai, K.; Imrek, J.; Inaba, M.; Iordanova, A.; Isenhower, D.; Ishihara, M.; Isobe, T.; Issah, M.; Isupov, A.; Ivanischev, D.; Ivanishchev, D.; Jacak, B. V.; Javani, M.; Jia, J.; Jiang, X.; Jin, J.; Johnson, B. M.; Joo, K. S.; Jouan, D.; Jumper, D. S.; Kajihara, F.; Kametani, S.; Kamihara, N.; Kamin, J.; Kaneti, S.; Kang, B. H.; Kang, J. H.; Kang, J. S.; Kapustinsky, J.; Karatsu, K.; Kasai, M.; Kawall, D.; Kawashima, M.; Kazantsev, A. V.; Kempel, T.; Khanzadeev, A.; Kijima, K. M.; Kim, B. I.; Kim, C.; Kim, D. H.; Kim, D. J.; Kim, E.; Kim, E.-J.; Kim, H. J.; Kim, K.-B.; Kim, S. H.; Kim, Y.-J.; Kim, Y. K.; Kinney, E.; Kiriluk, K.; Kiss, Á.; Kistenev, E.; Klatsky, J.; Kleinjan, D.; Kline, P.; Kochenda, L.; Komatsu, Y.; Komkov, B.; Konno, M.; Koster, J.; Kotchetkov, D.; Kotov, D.; Kozlov, A.; Král, A.; Kravitz, A.; Krizek, F.; Kunde, G. J.; Kurita, K.; Kurosawa, M.; Kwon, Y.; Kyle, G. S.; Lacey, R.; Lai, Y. S.; Lajoie, J. G.; Lebedev, A.; Lee, B.; Lee, D. M.; Lee, J.; Lee, K.; Lee, K. B.; Lee, K. S.; Lee, S. H.; Lee, S. R.; Leitch, M. J.; Leite, M. A. L.; Leitgab, M.; Leitner, E.; Lenzi, B.; Lewis, B.; Li, X.; Liebing, P.; Lim, S. H.; Linden Levy, L. A.; Liška, T.; Litvinenko, A.; Liu, H.; Liu, M. X.; Love, B.; Luechtenborg, R.; Lynch, D.; Maguire, C. F.; Makdisi, Y. I.; Makek, M.; Malakhov, A.; Malik, M. D.; Manion, A.; Manko, V. I.; Mannel, E.; Mao, Y.; Masui, H.; Masumoto, S.; Matathias, F.; McCumber, M.; McGaughey, P. L.; McGlinchey, D.; McKinney, C.; Means, N.; Mendoza, M.; Meredith, B.; Miake, Y.; Mibe, T.; Mignerey, A. C.; Mikeš, P.; Miki, K.; Milov, A.; Mishra, D. K.; Mishra, M.; Mitchell, J. T.; Miyachi, Y.; Miyasaka, S.; Mohanty, A. K.; Moon, H. J.; Morino, Y.; Morreale, A.; Morrison, D. P.; Motschwiller, S.; Moukhanova, T. V.; Murakami, T.; Murata, J.; Nagae, T.; Nagamiya, S.; Nagle, J. L.; Naglis, M.; Nagy, M. I.; Nakagawa, I.; Nakamiya, Y.; Nakamura, K. R.; Nakamura, T.; Nakano, K.; Nattrass, C.; Nederlof, A.; Newby, J.; Nguyen, M.; Nihashi, M.; Nouicer, R.; Novitzky, N.; Nyanin, A. S.; O'Brien, E.; Oda, S. X.; Ogilvie, C. A.; Oka, M.; Okada, K.; Onuki, Y.; Oskarsson, A.; Ouchida, M.; Ozawa, K.; Pak, R.; Pantuev, V.; Papavassiliou, V.; Park, B. H.; Park, I. H.; Park, J.; Park, S. K.; Park, W. J.; Pate, S. F.; Patel, L.; Pei, H.; Peng, J.-C.; Pereira, H.; Peresedov, V.; Peressounko, D. Yu.; Petti, R.; Pinkenburg, C.; Pisani, R. P.; Proissl, M.; Purschke, M. L.; Purwar, A. K.; Qu, H.; Rak, J.; Rakotozafindrabe, A.; Ravinovich, I.; Read, K. F.; Reygers, K.; Reynolds, D.; Riabov, V.; Riabov, Y.; Richardson, E.; Riveli, N.; Roach, D.; Roche, G.; Rolnick, S. D.; Rosati, M.; Rosen, C. A.; Rosendahl, S. S. E.; Rosnet, P.; Rukoyatkin, P.; Ružička, P.; Sahlmueller, B.; Saito, N.; Sakaguchi, T.; Sakashita, K.; Samsonov, V.; Sano, M.; Sano, S.; Sarsour, M.; Sato, T.; Sawada, S.; Sedgwick, K.; Seele, J.; Seidl, R.; Semenov, A. Yu.; Sen, A.; Seto, R.; Sharma, D.; Shein, I.; Shibata, T.-A.; Shigaki, K.; Shimomura, M.; Shoji, K.; Shukla, P.; Sickles, A.; Silva, C. L.; Silvermyr, D.; Silvestre, C.; Sim, K. S.; Singh, B. K.; Singh, C. P.; Singh, V.; Slunečka, M.; Soltz, R. A.; Sondheim, W. E.; Sorensen, S. P.; Soumya, M.; Sourikova, I. V.; Sparks, N. A.; Stankus, P. W.; Stenlund, E.; Stepanov, M.; Ster, A.; Stoll, S. P.; Sugitate, T.; Sukhanov, A.; Sun, J.; Sziklai, J.; Takagui, E. M.; Takahara, A.; Taketani, A.; Tanabe, R.; Tanaka, Y.; Taneja, S.; Tanida, K.; Tannenbaum, M. J.; Tarafdar, S.; Taranenko, A.; Tarján, P.; Tennant, E.; Themann, H.; Thomas, T. L.; Todoroki, T.; Togawa, M.; Toia, A.; Tomášek, L.; Tomášek, M.; Torii, H.; Towell, R. S.; Tserruya, I.; Tsuchimoto, Y.; Tsuji, T.; Vale, C.; Valle, H.; van Hecke, H. W.; Vargyas, M.; Vazquez-Zambrano, E.; Veicht, A.; Velkovska, J.; Vértesi, R.; Vinogradov, A. A.; Virius, M.; Vossen, A.; Vrba, V.; Vznuzdaev, E.; Wang, X. R.; Watanabe, D.; Watanabe, K.; Watanabe, Y.; Watanabe, Y. S.; Wei, F.; Wei, R.; Wessels, J.; Whitaker, S.; White, S. N.; Winter, D.; Wolin, S.; Wood, J. P.; Woody, C. L.; Wright, R. M.; Wysocki, M.; Xie, W.; Yamaguchi, Y. L.; Yamaura, K.; Yang, R.; Yanovich, A.; Ying, J.; Yokkaichi, S.; You, Z.; Young, G. R.; Younus, I.; Yushmanov, I. E.; Zajc, W. A.; Zelenski, A.; Zhang, C.; Zhou, S.; Zolin, L.; Phenix Collaboration

2015-06-01

The PHENIX experiment at RHIC has measured the centrality dependence of the direct photon yield from Au +Au collisions at √{sNN}=200 GeV down to pT=0.4 GeV /c . Photons are detected via photon conversions to e+e- pairs and an improved technique is applied that minimizes the systematic uncertainties that usually limit direct photon measurements, in particular at low pT. We find an excess of direct photons above the Ncoll-scaled yield measured in p +p collisions. This excess yield is well described by an exponential distribution with an inverse slope of about 240 MeV /c in the pT range 0.6 -2.0 GeV /c . While the shape of the pT distribution is independent of centrality within the experimental uncertainties, the yield increases rapidly with increasing centrality, scaling approximately with Npartα, where α =1.38 ±0.03 (stat )±0.07 (syst ) .

Tracing origins of complex pharmaceutical preparations using surface desorption atmospheric pressure chemical ionization mass spectrometry.

PubMed

Zhang, Xinglei; Jia, Bin; Huang, Keke; Hu, Bin; Chen, Rong; Chen, Huanwen

2010-10-01

A novel strategy to trace the origins of commercial pharmaceutical products has been developed based on the direct chemical profiling of the pharmaceutical products by surface desorption atmospheric pressure chemical ionization mass spectrometry (DAPCI-MS). Besides the unambiguous identification of active drug components, various compounds present in the matrixes are simultaneously detected without sample pretreatment, providing valuable information for drug quality control and origin differentiation. Four sources of commercial amoxicillin products made by different manufacturers have been successfully differentiated. This strategy has been extended to secerning six sources of Liuwei Dihuang Teapills, which are herbal medicine preparations with extremely complex matrixes. The photolysis status of chemical drug products and the inferior natural herd medicine products prepared with different processes (e.g., extra heating) were also screened using the method reported here. The limit of detection achieved in the MS/MS experiments was estimated to be 1 ng/g for amoxicillin inside the capsule product. Our experimental data demonstrate that DAPCI-MS is a useful tool for rapid pharmaceutical analysis, showing promising perspectives for tracking the entire pharmaceutical supply chain to prevent counterfeit intrusions.

Influence of the reactant carbon-hydrogen-oxygen composition on the key products of the direct gasification of dewatered sewage sludge in supercritical water.

PubMed

Gong, Miao; Zhu, Wei; Fan, Yujie; Zhang, Huiwen; Su, Ying

2016-05-01

The supercritical water gasification of ten different types of dewatered sewage sludges was investigated to understand the relationship between sludge properties and gasification products. Experiments were performed in a high-pressure autoclave at 400°C for 60 min. Results showed that gasification of sewage sludge in supercritical water consists mainly of a gasification reaction, a carbonization reaction and a persistent organic pollutants synthesis reaction. Changes in the reactant C/H/O composition have significant effects on the key gasification products. Total gas production increased with increasing C/H2O of the reactant. The char/coke content increased with increasing C/H ratio of the reactant. A decrease in the C/O ratio of the reactant led to a reduction in polycyclic aromatic hydrocarbon formation. This means that we can adjust the reactant C/H/O composition by adding carbon-, hydrogen-, and oxygen-containing substances such as coal, algae and H2O2 to optimize hydrogen production and to inhibit an undesired by-product formation. Copyright © 2016 Elsevier Ltd. All rights reserved.

Multiplexed photoionization mass spectrometry investigation of the O( 3P) + propyne reaction

DOE PAGES

Savee, John D.; Borkar, Sampada; Welz, Oliver; ...

2015-05-18

Here, the reaction of O( 3P) + propyne (C 3H 4) was investigated at 298 K and 4 Torr using time-resolved multiplexed photoionization mass spectrometry and a synchrotron-generated tunable vacuum ultraviolet light source. The time-resolved mass spectra of the observed products suggest five major channels under our conditions: C 2H 3 + HCO, CH 3 + HCCO, H + CH 3CCO, C 2H 4 + CO, and C 2H 2 + H 2 + CO. The relative branching ratios for these channels were found to be 1.00, (0.35 ± 0.11), (0.18 ± 0.10), (0.73 ± 0.27), and (1.31 ± 0.62).more » In addition, we observed signals consistent with minor production of C 3H 3 + OH and H 2 + CH 2CCO, although we cannot conclusively assign them as direct product channels from O( 3P) + propyne. The direct abstraction mechanism plays only a minor role (≤1%), and we estimate that O( 3P) addition to the central carbon of propyne accounts for 10% of products, with addition to the terminal carbon accounting for the remaining 89%. The isotopologues observed in experiments using d1-propyne (CH 3CCD) and analysis of product branching in light of previously computed stationary points on the singlet and triplet potential energy surfaces (PESs) relevant to O( 3P) + propyne suggest that, under our conditions, (84 ± 14)% of the observed product channels from O( 3P) + propyne result from intersystem crossing from the initial triplet PES to the lower-lying singlet PES.« less

Linking phytoplankton and bacterioplankton community dynamics to iron-binding ligand production in a microcosm experiment

NASA Astrophysics Data System (ADS)

Hogle, S. L.; Bundy, R.; Barbeau, K.

2016-02-01

Several significant lines of evidence implicate heterotrophic bacterioplankton as agents of iron cycling and sources of iron-binding ligands in seawater, but direct and mechanistic linkages have mostly remained elusive. Currently, it is unknown how microbial community composition varies during the course of biogenic particle remineralization and how shifts in community structure are related to sources and sinks of Fe-binding ligands. In order to simulate the rise, decline, and ultimate remineralization of a phytoplankton bloom, we followed the production of different classes of Fe-binding ligands as measured by electrochemical techniques, Fe concentrations, and macronutrient concentrations in a series of iron-amended whole seawater incubations over a period of six days during a California Current Ecosystem Long Term Ecological Research (CCE-LTER) process cruise. At the termination of the experiment phytoplankton communities were similar across iron treatments, but high iron conditions generated greater phytoplankton biomass and increased nutrient drawdown suggesting that phytoplankton communities were in different phases of bloom development. Strikingly, L1 ligands akin to siderophores in binding strength were only observed in high iron treatments implicating phytoplankton bloom phase as an important control. Using high-throughput 16S rRNA gene surveys, we observed that the abundance of transiently dominant copiotroph bacteria were strongly correlated with L1 concentrations. However, incubations with similar L1 concentrations and binding strengths produced distinct copiotroph community profiles dominated by a few strains. We suggest that phytoplankton bloom maturity influences algal-associated heterotrophic community succession, and that L1 production is either directly or indirectly tied to the appearance and eventual dominance of rarely abundant copiotroph bacterial strains.

The Vibrio parahaemolyticus small RNA RyhB promotes production of the siderophore vibrioferrin by stabilizing the polycistronic mRNA.

PubMed

Tanabe, Tomotaka; Funahashi, Tatsuya; Nakao, Hiroshi; Maki, Jun; Yamamoto, Shigeo

2013-08-01

High-affinity iron acquisition in Vibrio parahaemolyticus is mediated by the cognate siderophore vibrioferrin. We have previously reported that the vibrioferrin biosynthesis operon (pvsOp) is regulated at the transcriptional level by the iron-responsive repressor Fur (T. Tanabe, T. Funahashi, H. Nakao, S. Miyoshi, S. Shinoda, and S. Yamamoto, J. Bacteriol. 185:6938-6949, 2003). In this study, we identified the Fur-regulated small RNA RyhB and the RNA chaperone Hfq protein as additional regulatory proteins of vibrioferrin biosynthesis. We found that vibrioferrin production was greatly impaired in both the ryhB and hfq deletion mutants, and a TargetRNA search (http://snowwhite.wellesley.edu/targetRNA/index2.html) revealed that the 5'-untranslated region of pvsOp mRNA (pvsOp 5'-UTR) contains a potential base-pairing region required for the formation of the RyhB-pvsOp 5'-UTR duplex. An electrophoresis mobility shift assay indicated that RyhB can directly bind to the pvsOp 5'-UTR with the aid of Hfq. Rifampin chase experiments indicated that the half-life of pvsOp mRNA in the ryhB and hfq mutants was approximately 3-fold shorter than that in the parental strain, suggesting that both RyhB and Hfq are engaged in the stabilization of pvsOp mRNA. Chrome azurol S assays followed by electrophoresis mobility shift assays and rifampin chase experiments carried out for mutant strains indicated that base pairing between RyhB and the pvsOp 5'-UTR results in an increase in the stability of pvsOp mRNA, thereby leading to the promotion of vibrioferrin production. It is unprecedented that RyhB confers increased stability on a polycistronic mRNA involved in siderophore biosynthesis as a direct target.

Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products.

PubMed

Kho, Dan T; Johnson, Rebecca H; O'Carroll, Simon J; Angel, Catherine E; Graham, E Scott

2017-09-21

Herein we demonstrate the sensitive nature of human blood-brain barrier (BBB) endothelial cells to sodium azide and its gaseous product. Sodium azide is known to be acutely cytotoxic at low millimolar concentrations, hence its use as a biological preservative (e.g., in antibodies). Loss of barrier integrity was noticed in experiments using Electric Cell-substrate Impedance Sensing (ECIS) biosensor technology, to measure endothelial barrier integrity continuously in real-time. Initially the effect of sodium azide was observed as an artefact where it was present in antibodies being employed in neutralisation experiments. This was confirmed where antibody clones that were azide-free did not mediate loss of barrier function. A delayed loss of barrier function in neighbouring wells implied the influence of a liberated gaseous product. ECIS technology demonstrated that the BBB endothelial cells had a lower level of direct sensitivity to sodium azide of ~3 µM. Evidence of gaseous toxicity was consistently observed at 30 µM and above, with disrupted barrier function and cell death in neighbouring wells. We highlight the ability of this cellular biosensor technology to reveal both the direct and gaseous toxicity mediated by sodium azide. The sensitivity and temporal dimension of ECIS technology was instrumental in these observations. These findings have substantial implications for the wide use of sodium azide in biological reagents, raising issues of their application in live-cell assays and with regard to the protection of the user. This research also has wider relevance highlighting the sensitivity of brain endothelial cells to a known mitochondrial disruptor. It is logical to hypothesise that BBB endothelial dysfunction due to mitochondrial dys-regulation could have an important but underappreciated role in a range of neurological diseases.

Historical Review of Uncommanded Lateral-Directional Motions at Transonic Conditions

NASA Technical Reports Server (NTRS)

Chambers, Joseph R.; Hall, Robert M.

2003-01-01

This paper presents the results of a survey of past experiences with uncommanded lateral-directional motions at transonic speeds during specific military aircraft programs. The effort was undertaken to provide qualitative and quantitative information on past airplane programs that might be of use to the participants in the joint NASA/Navy/Air Force Abrupt Wing Stall (AWS) Program. The AWS Program was initiated because of the experiences of the F/A-l8E/F development program, during which unexpected, severe wing-drop motions were encountered by preproduction aircraft at transonic conditions. These motions were judged to be significantly degrading to the primary mission requirements of the aircraft. Although the problem was subsequently solved for the production version of the F/A-l8E/F, a high-level review panel emphasized the poor understanding of such phenomena and issued a strong recommendation to: "Initiate a national research effort to thoroughly and systematically study the wing drop phenomena." A comprehensive, cooperative NASA/Navy/Air Force AWS Program was designed to respond to provide the required technology requirements. As part of the AWS Program, a work element was directed at a historical review of wing-drop experiences in past aircraft development programs at high subsonic and transonic speeds. In particular, information was requested regarding: specific aircraft configurations that exhibited uncommanded motions and the nature of the motions; geometric characteristics of the air- planes; flight conditions involved in occurrences; relevant data, including wind-tunnel, computational, and flight sources; figures of merit used for analyses; and approaches used to alleviate the problem. An attempt was also made to summarize some of the more important lessons learned from past experiences, and to recommend specific research efforts. In addition to providing technical information to assist the AWS research objectives, the study produced fundamental information regarding the historical challenge of uncommanded lateral-directional motions at transonic conditions and the associated aerodynamic phenomena.

Historical Review of Uncommanded Lateral-Directional Motions At Transonic Conditions (Invited)

NASA Technical Reports Server (NTRS)

Chambers, Joseph R.; Hall, Robert M.

2003-01-01

This paper presents the results of a survey of past experiences with uncommanded lateral-directional motions at transonic speeds during specific military aircraft programs. The effort was undertaken to provide qualitative and quantitative information on past airplane programs that might be of use to the participants in the joint NASA/Navy/Air Force Abrupt Wing Stall (AWS) Program. The AWS Program was initiated because of the experiences of the F/A-18E/F development program, during which unexpected, severe wing-drop motions were encountered by preproduction aircraft at transonic conditions. These motions were judged to be significantly degrading to the primary mission requirements of the aircraft. Although the problem was subsequently solved for the production version of the F/A-l8E/F, a high-level review panel emphasized the poor understanding of such phenomena and issued a strong recommendation to: Initiate a national research effort to thoroughly and systematically study the wing drop phenomena. A comprehensive, cooperative NASA/Navy/Air Force AWS Program was designed to respond to provide the required technology requirements. As part of the AWS Program, a work element was directed at a historical review of wing-drop experiences in past aircraft development programs at high subsonic and transonic speeds. In particular, information was requested regarding: specific aircraft configurations that exhibited uncommanded motions and the nature of the motions; geometric characteristics of the air- planes; flight conditions involved in occurrences; relevant data, including wind-tunnel, computational, and flight sources; figures of merit used for analyses; and approaches used to alleviate the problem. An attempt was also made to summarize some of the more important lessons learned from past experiences, and to recommend specific research efforts. In addition to providing technical information to assist the AWS research objectives, the study produced fundamental information regarding the historical challenge of uncommanded lateral-directional motions at transonic conditions and the associated aerodynamic phenomena.

Transformation efficiency and formation of transformation products during photochemical degradation of TCE and PCE at micromolar concentrations

PubMed Central

2014-01-01

Background Trichloroethene and tetrachloroethene are the most common pollutants in groundwater and two of the priority pollutants listed by the U.S. Environmental Protection Agency. In previous studies on TCE and PCE photolysis and photochemical degradation, concentration ranges exceeding environmental levels by far with millimolar concentrations of TCE and PCE have been used, and it is not clear if the obtained results can be used to explain the degradation of these contaminants at more realistic environmental concentration levels. Methods Experiments with micromolar concentrations of TCE and PCE in aqueous solution using direct photolysis and UV/H2O2 have been conducted and product formation as well as transformation efficiency have been investigated. SPME/GC/MS, HPLC/UV and ion chromatography with conductivity detection have been used to determine intermediates of degradation. Results The results showed that chloride was a major end product in both TCE and PCE photodegradation. Several intermediates such as formic acid, dichloroacetic acid, dichloroacetaldehyede, chloroform, formaldehyde and glyoxylic acid were formed during both, UV and UV/H2O2 treatment of TCE. However chloroacetaldehyde and chloroacetic acid were only detected during direct UV photolysis of TCE and oxalic acid was only formed during the UV/H2O2 process. For PCE photodegradation, formic acid, di- and trichloroacetic acids were detected in both UV and UV/H2O2 systems, but formaldehyde and glyoxylic acid were only detected during direct UV photolysis. Conclusions For water treatment UV/H2O2 seems to be favorable over direct UV photolysis because of its higher degradation efficiency and lower risk for the formation of harmful intermediates. PMID:24401763

Transformation efficiency and formation of transformation products during photochemical degradation of TCE and PCE at micromolar concentrations.

PubMed

Dobaradaran, Sina; Lutze, Holger; Mahvi, Amir Hossein; Schmidt, Torsten C

2014-01-08

Trichloroethene and tetrachloroethene are the most common pollutants in groundwater and two of the priority pollutants listed by the U.S. Environmental Protection Agency. In previous studies on TCE and PCE photolysis and photochemical degradation, concentration ranges exceeding environmental levels by far with millimolar concentrations of TCE and PCE have been used, and it is not clear if the obtained results can be used to explain the degradation of these contaminants at more realistic environmental concentration levels. Experiments with micromolar concentrations of TCE and PCE in aqueous solution using direct photolysis and UV/H2O2 have been conducted and product formation as well as transformation efficiency have been investigated. SPME/GC/MS, HPLC/UV and ion chromatography with conductivity detection have been used to determine intermediates of degradation. The results showed that chloride was a major end product in both TCE and PCE photodegradation. Several intermediates such as formic acid, dichloroacetic acid, dichloroacetaldehyede, chloroform, formaldehyde and glyoxylic acid were formed during both, UV and UV/H2O2 treatment of TCE. However chloroacetaldehyde and chloroacetic acid were only detected during direct UV photolysis of TCE and oxalic acid was only formed during the UV/H2O2 process. For PCE photodegradation, formic acid, di- and trichloroacetic acids were detected in both UV and UV/H2O2 systems, but formaldehyde and glyoxylic acid were only detected during direct UV photolysis. For water treatment UV/H2O2 seems to be favorable over direct UV photolysis because of its higher degradation efficiency and lower risk for the formation of harmful intermediates.

Radon in the DRIFT-II directional dark matter TPC: emanation, detection and mitigation

NASA Astrophysics Data System (ADS)

Battat, J. B. R.; Brack, J.; Daw, E.; Dorofeev, A.; Ezeribe, A. C.; Fox, J. R.; Gauvreau, J.-L.; Gold, M.; Harmon, L. J.; Harton, J. L.; Landers, J. M.; Lee, E. R.; Loomba, D.; Matthews, J. A. J.; Miller, E. H.; Monte, A.; Murphy, A. StJ.; Paling, S. M.; Phan, N.; Pipe, M.; Robinson, M.; Sadler, S. W.; Scarff, A.; Snowden-Ifft, D. P.; Spooner, N. J. C.; Telfer, S.; Walker, D.; Warner, D.; Yuriev, L.

2014-11-01

Radon gas emanating from materials is of interest in environmental science and also a major concern in rare event non-accelerator particle physics experiments such as dark matter and double beta decay searches, where it is a major source of background. Notable for dark matter experiments is the production of radon progeny recoils (RPRs), the low energy (~ 100 keV) recoils of radon daughter isotopes, which can mimic the signal expected from WIMP interactions. Presented here are results of measurements of radon emanation from detector materials in the 1 m3 DRIFT-II directional dark matter gas time projection chamber experiment. Construction and operation of a radon emanation facility for this work is described, along with an analysis to continuously monitor DRIFT data for the presence of internal 222Rn and 218Po. Applying this analysis to historical DRIFT data, we show how systematic substitution of detector materials for alternatives, selected by this device for low radon emanation, has resulted in a factor of ~ 10 reduction in internal radon rates. Levels are found to be consistent with the sum from separate radon emanation measurements of the internal materials and also with direct measurement using an attached alpha spectrometer. The current DRIFT detector, DRIFT-IId, is found to have sensitivity to 222Rn of 2.5 μBql-1 with current analysis efficiency, potentially opening up DRIFT technology as a new tool for sensitive radon assay of materials.

A Tiered Mentoring Model of Exposing and Engaging Students with Research Throughout the Undergraduate Curriculum

NASA Astrophysics Data System (ADS)

Guerard, J.; Hayes, S. M.

2015-12-01

Incorporating research into undergraduate curricula has been linked to improved critical thinking, intellectual independence, and student retention, resulting in a graduating population more ready for the workforce or graduate school. We have designed a three-tier model of undergraduate chemistry courses that enable first-year students with no previous research experience to gain the skills needed to develop, fund and execute independent research projects by the close of their undergraduate studies. First-year students are provided with context through a broadly focused introductory class that exposes them to current faculty research activities, and also gives them direct experience with the research process through peer mentored research teams as they participate in faculty-directed projects. Mid-career undergraduate students receive exposure and support in two formats: illustrative examples from current faculty research are incorporated into lessons in core classes, and courses specially designed to foster research independence. This is done by providing content and process mentoring as students develop independent projects, write proposals, and build relationships with faculty and graduate students in research groups. Advanced undergraduates further develop their research independence performing student-designed projects with faculty collaboration that frequently result in tangible research products. Further, graduate students gain experience in mentoring though formal training, as well as through actively mentoring mid-career undergraduates. This novel, integrated approach enables faculty to directly incorporate their research into all levels of the undergraduate curriculum while fostering undergraduates in developing and executing independent projects and empowering mentoring relationships.

A nanobody directed to a functional epitope on VEGF, as a novel strategy for cancer treatment.

PubMed

Farajpour, Zahra; Rahbarizadeh, Fatemeh; Kazemi, Bahram; Ahmadvand, Davoud

2014-03-28

Compelling evidence suggests that vascular endothelial growth factor (VEGF), due to its essential role in angiogenesis, is a critical target for cancer treatment. Neutralizing monoclonal antibodies against VEGF are important class of drugs used in cancer therapy. However, the cost of production, large size, and immunogenicity are main drawbacks of conventional monoclonal therapy. Nanobodies are the smallest antigen-binding antibody fragments, which occur naturally in camelidae. Because of their remarkable features, we decided to use an immune library of nanobody to direct phage display to recognition of novel functional epitopes on VEGF. Four rounds of selection were performed and six phage-displayed nanobodies were obtained from an immune phage library. The most reactive clone in whole-cell ELISA experiments, was purified and assessed in proliferation inhibition assay. Purified ZFR-5 not only blocked interaction of VEGF with its receptor in cell ELISA experiments, but also was able to significantly inhibit proliferation response of human umbilical vein endothelial cells to VEGF in a dose-dependent manner. Taken together, our study demonstrates that by using whole-cell ELISA experiments, nanobodies against antigenic regions included in interaction of VEGF with its receptors can be directed. Because of unique and intrinsic properties of a nanobody and the ability of selected nanobody for blocking the epitope that is important for biological function of VEGF, it represents novel potential drug candidate. Copyright © 2014 Elsevier Inc. All rights reserved.

No direct by maternal effects interaction detected for pre-weaning growth in Romane sheep using a reaction norm model.

PubMed

David, Ingrid; Bouvier, Frédéric; Ricard, Edmond; Ruesche, Julien; Weisbecker, Jean-Louis

2013-09-30

The pre-weaning growth of lambs, an important component of meat production, depends on maternal and direct effects. These effects cannot be observed directly and models used to study pre-weaning growth assume that they are additive. However, it is reasonable to suggest that the influence of direct effects on growth may differ depending on the value of maternal effects i.e. an interaction may exist between the two components. To test this hypothesis, an experiment was carried out in Romane sheep in order to obtain observations of maternal phenotypic effects (milk yield and milk quality) and pre-weaning growth of the lambs. The experiment consisted of mating ewes that had markedly different maternal genetic effects with rams that contributed very different genetic effects in four replicates of a 3 × 2 factorial plan. Milk yield was measured using the lamb suckling weight differential technique and milk composition (fat and protein contents) was determined by infrared spectroscopy at 15, 21 and 35 days after lambing. Lambs were weighed at birth and then at 15, 21 and 35 days. An interaction between genotype (of the lamb) and environment (milk yield and quality) for average daily gain was tested using a restricted likelihood ratio test, comparing a linear reaction norm model (interaction model) to a classical additive model (no interaction model). A total of 1284 weights of 442 lambs born from 166 different ewes were analysed. On average, the ewes produced 2.3 ± 0.8 L milk per day. The average protein and fat contents were 50 ± 4 g/L and 60 ± 18 g/L, respectively. The mean 0-35 day average daily gain was 207 ± 46 g/d. Results of the restricted likelihood ratio tests did not highlight any significant interactions between the genotype of the lambs and milk production of the ewe. Our results support the hypothesis of additivity of maternal and direct effects on growth that is currently applied in genetic evaluation models.

Production of neutrinos and neutrino-like particles in proton-nucleus interactions. [400 GeV, cross sections

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dishaw, J.P.

1979-03-01

An experimental search was performed to look for the direct production of neutrinos or neutrino-like particles, i.e., neutral particles which interact weakly with hadrons, in proton-nucleus interactions at 400 GeV incident proton energy. Possible sources of such particles include the semi-leptonic decay of new heavy particles such as charm, and the direct production of a light neutral Higgs particle such as the axion. The production of these particles has been inferred in this experiment by energy nonconservation in the collision of a proton with an iron nucleus. The total visible energy of the interaction was measured using a sampling ionizationmore » calorimeter. After correcting for beam intensity effects and cutting the data to eliminate systematic effects in the measurement, the final resolution of the calorimeter was 3.51% and increased with decreasing incident beam energy with a square root dependence on the beam energy. Energy nonconservation in the data is manifest as a non-Gaussian distribution on the low side of the calorimeter measured energy. Model calculations yield the fraction of events expected in this non-Gaussian behavior for the various sources of neutrinos or neutrino-like particles. A maximum likelihood fit to the data with the theoretical fraction of events expected yields the 95% confidence level production cross section upper limit values. The upper limits for general production of neutrino-like particles for various parameterizations of the production cross section are presented. The following specific upper limits have been established: charm particle production < 670 ..mu..barns, supersymmetric particle production carrying an additional quantum number R < 33 ..mu..barns (mass of 1 GeV), 8 ..mu..barns (mass of 3 GeV); axion production < 10/sup -3/ times the ..pi../sup 0/ production cross section. 144 references.« less

Search for the direct production of charginos, neutralinos and staus in final states with at least two hadronically decaying taus and missing transverse momentum in pp collisions at $$ \\sqrt{s}=8 $$ TeV with the ATLAS detector

DOE PAGES

Aad, G.; Abbott, B.; Abdallah, J.; ...

2014-10-16

We present results of a search for the electroweak associated production of charginos and next-to-lightest neutralinos, pairs of charginos or pairs of tau sleptons. These processes are characterised by final states with at least two hadronically decaying tau leptons, missing transverse momentum and low jet activity. The analysis is based on an integrated luminosity of 20.3 fb ₋1 of proton-proton collisions at √s = 8TeV recorded with the ATLAS experiment at the Large Hadron Collider. We observed no significant excess with respect to the predictions from Standard Model processes. Limits are set at 95% confidence level on the masses ofmore » the lighter chargino and next-to-lightest neutralino for various hypotheses for the lightest neutralino mass in simplified models. In the scenario of direct production of chargino pairs, with each chargino decaying into the lightest neutralino via an intermediate tau slepton, chargino masses up to 345 GeV are excluded for a massless lightest neutralino. For associated production of mass-degenerate charginos and next-tolightest neutralinos, both decaying into the lightest neutralino via an intermediate tau slepton, masses up to 410 GeV are excluded for a massless lightest neutralino.« less

A nanobody directed to a functional epitope on VEGF, as a novel strategy for cancer treatment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farajpour, Zahra; Rahbarizadeh, Fatemeh, E-mail: rahbarif@modares.ac.ir; Kazemi, Bahram

Highlights: • A novel nanobody directed to antigenic regions on VEGF was identified. • Our nanobody was successfully purified. • Our nanobody significantly inhibited VEGF-induced proliferation of HUVECs in a dose dependent manner. - Abstract: Compelling evidence suggests that vascular endothelial growth factor (VEGF), due to its essential role in angiogenesis, is a critical target for cancer treatment. Neutralizing monoclonal antibodies against VEGF are important class of drugs used in cancer therapy. However, the cost of production, large size, and immunogenicity are main drawbacks of conventional monoclonal therapy. Nanobodies are the smallest antigen-binding antibody fragments, which occur naturally in camelidae.more » Because of their remarkable features, we decided to use an immune library of nanobody to direct phage display to recognition of novel functional epitopes on VEGF. Four rounds of selection were performed and six phage-displayed nanobodies were obtained from an immune phage library. The most reactive clone in whole-cell ELISA experiments, was purified and assessed in proliferation inhibition assay. Purified ZFR-5 not only blocked interaction of VEGF with its receptor in cell ELISA experiments, but also was able to significantly inhibit proliferation response of human umbilical vein endothelial cells to VEGF in a dose-dependent manner. Taken together, our study demonstrates that by using whole-cell ELISA experiments, nanobodies against antigenic regions included in interaction of VEGF with its receptors can be directed. Because of unique and intrinsic properties of a nanobody and the ability of selected nanobody for blocking the epitope that is important for biological function of VEGF, it represents novel potential drug candidate.« less

Indications of Bulk-Fluid Motion in Direct-Drive Implosions

NASA Astrophysics Data System (ADS)

Mannion, O. M.; Anderson, K. S.; Forrest, C. J.; Glebov, V. Yu.; Goncharov, V. N.; Knauer, J. P.; Radha, P. B.; Regan, S. P.; Sangster, T. C.; Stoeckl, C.

2017-10-01

The neutron spectrum produced by a burning plasma encodes essential information about the fusion products and serves as an important diagnostic for inertial confinement fusion experiments. At the Omega Laser Facility, neutron time-of-flight measurements are used to interpret the first and second moment of the neutron spectrum. These moments have been shown to be directly related to properties of the plasma, such as bulk fluid motion and apparent ion temperature. New measurement devices allow for unprecedented accuracy in the measurement of these moments and will provide a better understanding of the performance of direct-drive implosions. We present measurements of the first moment of the DT and D2 peaks in DT implosions and show that variations in the first moment indicate bulk fluid motion of the plasma. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

Direct three-dimensional observation of the microstructure and chemistry of C{sub 3}S hydration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hu, Qinang; Aboustait, Mohammed; Kim, Taehwan

Disagreements about the mechanisms of cement hydration remain despite the fact that portland cement has been studied extensively for over 100 years. One reason for this is that direct observation of the change in microstructure and chemistry are challenging for many experimental techniques. This paper presents results from synchrotron nano X-ray tomography and fluorescence imaging. The data show unprecedented direct observations of small collections of C{sub 3}S particles before and after different periods of hydration in 15 mmol/L lime solution. X-ray absorption contrast is used to make three dimensional maps of the changes of these materials with time. The chemicalmore » compositions of hydration products are then identified with X-ray fluorescence mapping and scanning electron microscopy. These experiments are used to provide insight into the rate and morphology of the microstructure formation.« less

A search for leptoquarks, leptogluons and excited leptons in H1 at HERA

NASA Astrophysics Data System (ADS)

Abt, I.; Ahmed, T.; Andreev, V.; Andrieu, B.; Appuhn, R.-D.; Arpagaus, M.; Babaev, A.; Bärwolff, H.; Bán, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Bassler, U.; Beck, H. P.; Behrend, H.-J.; Belousov, A.; Berger, Ch.; Bergstein, H.; Bernardi, G.; Bernet, R.; Bertrand-Coremans, G.; Besançon, M.; Biddulph, P.; Binder, E.; Bischoff, A.; Bizot, J. C.; Blobel, V.; Borras, K.; Bosetti, P. C.; Boudry, V.; Bourdarios, C.; Brasse, F.; Braun, U.; Braunschweig, W.; Brisson, V.; Bruncko, D.; Büngener, L.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Buschborn, G.; Campbell, A. J.; Carli, T.; Charles, F.; Clarke, D.; Clegg, A. B.; Colombo, M.; Coughlan, J. A.; Courau, A.; Coutures, Ch.; Cozzika, G.; Criegee, L.; Cvach, J.; Dagoret, S.; Dainton, J. B.; Danilov, M.; Dann, A. W. E.; Dau, W. D.; David, M.; Deffur, E.; Delcourt, B.; Del Buono, L.; Devel, M.; De Roeck, A.; Dingus, P.; Dollfus, C.; Dowell, J. D.; Dreis, H. B.; Drescher, A.; Duboc, J.; Düllmann, D.; Dünger, O.; Duhm, H.; Ebbinghaus, R.; Eberle, M.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichenberger, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellis, N. N.; Ellison, R. J.; Elsen, E.; Erdmann, M.; Evrard, E.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Fensome, I. F.; Ferencei, J.; Ferrarotto, F.; Flamm, K.; Flauger, W.; Fleischer, M.; Flügge, G.; Fomenko, A.; Fominykh, B.; Forbush, M.; Formánek, J.; Foster, J. M.; Franke, G.; Fretwurst, E.; Fuhrmann, P.; Gabathuler, E.; Gamerdinger, K.; Garvey, J.; Gayler, J.; Gellrich, A.; Gennis, M.; Genzel, H.; Gerhards, R.; Gillespie, D.; Godfrey, L.; Goerlach, U.; Goerlich, L.; Goldberg, M.; Goodall, A. M.; Gorelov, I.; Goritchev, P.; Grab, C.; Grässler, H.; Grässler, R.; Greenshaw, T.; Greif, H.; Grindhammer, G.; Gruber, C.; Haack, J.; Haidt, D.; Hajduk, L.; Hamon, O.; Handschuh, D.; Hanlon, E. M.; Hapke, M.; Harjes, J.; Haydar, R.; Haynes, W. J.; Heatherington, J.; Hedberg, V.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herma, R.; Herynek, I.; Hildesheim, W.; Hill, P.; Hilton, C. D.; Hladký, J.; Hoeger, K. C.; Huet, Ph.; Hufnagel, H.; Huot, N.; Ibbotson, M.; Itterbeck, H.; Jabiol, M. A.; Jacholkowska, A.; Jacobsson, C.; Jaffre, M.; Jansen, T.; Jönsson, L.; Johannsen, K.; Johnson, D. P.; Johnson, L.; Jung, H.; Kalmus, P. I. P.; Kasarian, S.; Kaschowitz, R.; Kasselmann, P.; Kathage, U.; Kaufmann, H. H.; Kenyon, I. R.; Kermiche, S.; Keuker, C.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Ko, W.; Köhler, T.; Kolanoski, H.; Kole, F.; Kolya, S. D.; Korbel, V.; Korn, M.; Kostka, P.; Kotelnikov, S. K.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Krüger, U.; Kubenka, J. P.; Küster, H.; Kuhlen, M.; Kurča, T.; Kurzhöfer, J.; Kuznik, B.; Lander, R.; Landon, M. P. J.; Lange, W.; Langkau, R.; Lanius, P.; Laporte, J. F.; Lebedev, A.; Leuschner, A.; Leverenz, C.; Levonian, S.; Lewin, D.; Ley, Ch.; Lindner, A.; Lindström, G.; Lipinski, J.; Loch, P.; Lohmander, H.; Lopez, G. C.; Lüers, D.; Magnussen, N.; Malinovski, E.; Mani, S.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Masson, S.; Mavroidis, A.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Mercer, D.; Merz, T.; Meyer, C. A.; Meyer, H.; Meyer, J.; Mikocki, S.; Milone, V.; Monnier, E.; Moreau, F.; Moreels, J.; Morris, J. V.; Müller, K.; Murín, P.; Murray, S. A.; Nagovizin, V.; Naroska, B.; Naumann, Th.; Newton, D.; Neyret, D.; Nguyen, H. K.; Niebergall, F.; Nisius, R.; Nowak, G.; Noyes, G. W.; Nyberg, M.; Oberlack, H.; Obrock, U.; Olsson, J. E.; Orenstein, S.; Ould-Saada, F.; Pascaud, C.; Patel, G. D.; Peppel, E.; Peters, S.; Pharabod, J. P.; Phillips, H. T.; Phillips, J. P.; Pichler, Ch.; Pilgram, W.; Pitzl, D.; Prosi, R.; Rädel, G.; Raupach, F.; Rauschnabel, K.; Reimer, P.; Ribarics, P.; Riech, V.; Riedlberger, J.; Rietz, M.; Robertson, S. M.; Robmann, P.; Roosen, R.; Rostovtsev, A.; Royon, C.; Rudowicz, M.; Ruffer, M.; Rusakov, S.; Rybicki, K.; Sahlmann, N.; Sanchez, E.; Sankey, D. P. C.; Savitsky, M.; Schacht, P.; Schleper, P.; von Schlippe, W.; Schmidt, C.; Schmidt, D.; Schmitz, W.; Schröder, V.; Schulz, M.; Schwind, A.; Scobel, W.; Seehausen, U.; Sell, R.; Seman, M.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shooshtari, H.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Smirnov, P.; Smith, J. R.; Smolik, L.; Soloviev, Y.; Spitzer, H.; Staroba, P.; Steenbock, M.; Steffen, P.; Steinberg, R.; Stella, B.; Stephens, K.; Stier, J.; Stösslein, U.; Strachota, J.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Taylor, R. E.; Thiebaux, C.; Thompson, G.; Tichomirov, I.; Trenkel, C.; Truöl, P.; Tchernyshov, V.; Turnau, J.; Tutas, J.; Urban, L.; Usik, A.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Esch, P.; Vartapetian, A.; Vazdik, Y.; Vecko, M.; Verrecchia, P.; Vick, R.; Villet, G.; Vogel, E.; Wacker, K.; Walker, I. W.; Walther, A.; Weber, G.; Wegener, D.; Wegner, A.; Wellisch, H. P.; Willard, S.; Winde, M.; Winter, G.-G.; Wolff, Th.; Womersley, L. A.; Wright, A. E.; Wulff, N.; Yiou, T. P.; Žáček, J.; Závada, P.; Zeitnitz, C.; Ziaeepour, H.; Zimmer, M.; Zimmermann, W.; Zomer, F.; H1 Collaboration

1993-05-01

A direct search for new particles in the H1 experiment at HERA is presented for masses ranging from 35 GeV up to ˜ 250 GeV. The data sample of 24 nb -1 accumulated during the first year of operation was analysed for signatures of scalar and vector leptoquarks, leptogluons, excited electrons and excited neutrinos with flavours of the first generation. No evidence for the production of such particles was found in various possible decay channels. Rejection limits are derived.

Modelling of evaporation of a dispersed liquid component in a chemically active gas flow

NASA Astrophysics Data System (ADS)

Kryukov, V. G.; Naumov, V. I.; Kotov, V. Yu.

1994-01-01

A model has been developed to investigate evaporation of dispersed liquids in chemically active gas flow. Major efforts have been directed at the development of algorithms for implementing this model. The numerical experiments demonstrate that, in the boundary layer, significant changes in the composition and temperature of combustion products take place. This gives the opportunity to more correctly model energy release processes in combustion chambers of liquid-propellant rocket engines, gas-turbine engines, and other power devices.

First negative ion beam measurement by the Short-Time Retractable Instrumented Kalorimeter Experiment (STRIKE)

NASA Astrophysics Data System (ADS)

Serianni, G.; De Muri, M.; Muraro, A.; Veltri, P.; Bonomo, F.; Chitarin, G.; Pasqualotto, R.; Pavei, M.; Rizzolo, A.; Valente, M.; Franzen, P.; Ruf, B.; Schiesko, L.

2014-02-01

The Source for Production of Ion of Deuterium Extracted from Rf plasma (SPIDER) test facility is under construction in Padova to optimise the operation of the beam source of ITER neutral beam injectors. The SPIDER beam will be characterised by the instrumented calorimeter STRIKE, whose main components are one-directional carbon-fibre-carbon-composite tiles. A small-scale version of the entire system has been employed in the BAvarian Test MAchine for Negative ions (BATMAN) testbed by arranging two prototype tiles in the vertical direction. The paper presents a description of the mini-STRIKE system and of the data analysis procedures, as well as some results concerning the BATMAN beam under varying operating conditions.

Turbulent unmixing: how marine turbulence drives patchy distributions of motile phytoplankton

NASA Astrophysics Data System (ADS)

Durham, William; Climent, Eric; Barry, Michael; de Lillo, Filippo; Boffetta, Guido; Cencini, Massimo; Stocker, Roman

2013-11-01

Centimeter-scale patchiness in the distribution of phytoplankton increases the efficacy of many important ecological interactions in the marine food web. We show that turbulent fluid motion, usually synonymous with mixing, instead triggers intense small-scale patchiness in the distribution of motile phytoplankton. We use a suite of experiments, direct numerical simulations of turbulence, and analytical tools to show that turbulent shear and acceleration directs the motility of cells towards well-defined regions of flow, increasing local cell concentrations more than ten fold. This motility-driven `unmixing' offers an explanation for why motile cells are often more patchily distributed than non-motile cells and provides a mechanistic framework to understand how turbulence, whose strength varies profoundly in marine environments, impacts ocean productivity.

A requirements specification for a software design support system

NASA Technical Reports Server (NTRS)

Noonan, Robert E.

1988-01-01

Most existing software design systems (SDSS) support the use of only a single design methodology. A good SDSS should support a wide variety of design methods and languages including structured design, object-oriented design, and finite state machines. It might seem that a multiparadigm SDSS would be expensive in both time and money to construct. However, it is proposed that instead an extensible SDSS that directly implements only minimal database and graphical facilities be constructed. In particular, it should not directly implement tools to faciliate language definition and analysis. It is believed that such a system could be rapidly developed and put into limited production use, with the experience gained used to refine and evolve the systems over time.

Mechanisms of the effect of VUV radiation on the microfungi

NASA Astrophysics Data System (ADS)

Zvereva, Galina; Kirtsideli, Irina; Machs, Eduard; Vangonen, Albert

2018-04-01

The mechanisms of the effect of vacuum ultraviolet (VUV) radiation (λ = 172 nm) on various types of microfungi spores were investigated. It is found that there are several parallel direct and indirect mechanisms, which lead to spores inactivation, including destruction of the cell wall and DNA by means of direct absorption of VUV radiation and by VUV photolysis reactive products. IR transmission spectra indicate the etching of the spore cell wall material with the predominant degradation of the polysaccharides. Electrophoresis of irradiated spores DNA shows heavy (about 20 000 pairs of nucleotides) and light fragments appearance. Experiments using an antioxidant (iodine) indicate the participation of reactive radicals in inactivation, which provide not less than 10% of inactivated cells

EZStream: Distributing Live ISS Experiment Telemetry via Internet

NASA Technical Reports Server (NTRS)

Myers, Gerry; Welch, Clara L. (Technical Monitor)

2002-01-01

This paper will present the high-level architecture and components of the current version of EZStream as well as the product direction & enhancements to be incorporated through a Phase II grant. Security will be addressed such as data encryption and user login. Remote user devices will be discussed including web browsers on PC's and displays on PDA's and smart cell phones. The interaction between EZStream and TReK will be covered as well as the eventuality of EZStream to receive and parse binary data streams directly. This makes EZStream beneficial to both the International Partners and non-NASA applications. The options of developing client-side display web pages will be addressed and the development of new tools to allow creation of display web pages by non-programmers.

First negative ion beam measurement by the Short-Time Retractable Instrumented Kalorimeter Experiment (STRIKE)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Serianni, G., E-mail: gianluigi.serianni@igi.cnr.it; De Muri, M.; Veltri, P.

2014-02-15

The Source for Production of Ion of Deuterium Extracted from Rf plasma (SPIDER) test facility is under construction in Padova to optimise the operation of the beam source of ITER neutral beam injectors. The SPIDER beam will be characterised by the instrumented calorimeter STRIKE, whose main components are one-directional carbon-fibre-carbon-composite tiles. A small-scale version of the entire system has been employed in the BAvarian Test MAchine for Negative ions (BATMAN) testbed by arranging two prototype tiles in the vertical direction. The paper presents a description of the mini-STRIKE system and of the data analysis procedures, as well as some resultsmore » concerning the BATMAN beam under varying operating conditions.« less

Energy balance in man measured by direct and indirect calorimetry.

PubMed

Webb, P; Annis, J F; Troutman, S J

1980-06-01

In six 24-hr measurements of energy balance, direct and indirect calorimetry agreed within +/-3%, which is probably the range of experimental error. But in seven other 24-hr periods there was disagreement in the range of 8 to 23%, and these were usually days when the subjects ate much less than they spent metabolically. Our direct calorimeter is an insulated, water cooled suit. Continous measurements of O2 consumption and CO2 production provided data on metabolic expenditure (M) by indirect calorimetry. The 24-hr values for M matched the energy losses within +/-60 kcal (+/-3% of M) in four men who rested all day and lay down to sleep at night. Similar agreement was seen in one of the four who worked on a treadmill for 4 hr and stayed busy all day. but in another energy losses were 342 kcal greater than M (10% of M). When the experiments gave values for M minus the losses greater than +/-60 kcal, this is called "unmeasured energy". In further experiments, two subjects stayed awake for 24 hr, and their unmeasured energies were 279 and 393 kcal. The same two men, eating sparingly, also worked for 24 hr so as to double their resting metabolic expenditures; the unmeasured energies were even larger, 380 and 958 kcal. When they repeated the 24 hr of mild work, but ate nearly as much as they spent metabolically, one man was near energy balance, while the other showed an unmeasured energy of -363 kcal. Little heat storage was evident in these experiments; therefore, heat balance was present and energy balance should have been present. In the group of 13 experiments, it appeared that the greater the food deficit, the larger was the unmeasured energy (excess of metabolic expenditure over loss of energy).

Directed Forgetting of Recently Recalled Autobiographical Memories

ERIC Educational Resources Information Center

Barnier, Amanda J.; Conway, Martin A.; Mayoh, Lyndel; Speyer, Joanne; Avizmil, Orit; Harris, Celia B.

2007-01-01

In 6 experiments, the authors investigated list-method directed forgetting of recently recalled autobiographical memories. Reliable directed forgetting effects were observed across all experiments. In 4 experiments, the authors examined the impact of memory valence on directed forgetting. The forget instruction impaired recall of negative,…

Readability of Directions on Potentially Hazardous Household Products

ERIC Educational Resources Information Center

Pyrczak, Fred

1976-01-01

The study focused on an analysis of the readability of directions on harmful household products. High school students' reading ability was tested using eight sets of sample directions. The results of the study indicate a need for improving the students' ability to read directions on such products. (EC)

77 FR 42016 - Product Change-Every Door Direct Mail-Retail

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-17

... POSTAL SERVICE Product Change--Every Door Direct Mail--Retail AGENCY: Postal Service\\TM\\. ACTION... Regulatory Commission to add Every Door Direct Mail--Retail to the market-dominant product list within the... Request of the United States Postal Service to Add Every Door Direct Mail--Retail to the Mail...

Supporting Interdisciplinary Collaboration Through Reusable Free Software. A Research Student Experience

NASA Astrophysics Data System (ADS)

Dimech, C.

2013-12-01

In this contribution, I present a critical evaluation of my experience as a research student conducting an interdisciplinary project that bridges the world of geoscience with that of astronomy. The major challenge consists in studying and modifying existing geophysical software to work with synthetic solar data not obtained by direct measurement but useful for testing and evaluation, and data released from the satellite HINODE and the Solar Dynamics Observatory. I have been fortunate to collaborate closely with multiple geoscientists keen to share their software codes and help me understand their implementations so I can extend the methodology to solve problems in solar physics. Moreover, two additional experiences have helped me develop my research and collaborative skills. First was an opportunity to involve an undergraduate student, and secondly, my participation at the GNU Hackers Meeting in Paris. Three aspects that need particular attention to enhance the collective productivity of any group of individuals keen to extend existing codes to achieve further interdisciplinary goals have been identified. (1) The production of easily reusable code that users can study and modify even when large sets of computations are involved. (2) The transformation of solutions into tools that are 100% free software. (3) The harmonisation of collaborative interactions that effectively tackle the two aforementioned tasks. Each one will be discussed in detail during this session based on my experience as a research student.

Workplace Breastfeeding Support Varies by Employment Type: The Service Workplace Disadvantage.

PubMed

Snyder, Kailey; Hansen, Kelli; Brown, Sara; Portratz, Amy; White, Kate; Dinkel, Danae

The majority of women are returning to work full-time after childbirth, and support within their place of employment may influence intention and duration for breastfeeding, but more research is needed. Therefore, the purpose of this study was to explore the influence of employment type on breastfeeding duration upon return to work by examining informal (i.e., verbal encouragement) and direct (i.e., lactation space, flexible time) factors of support. This was a retrospective survey of women's returning-to-work experiences while breastfeeding. Survey contents included respondent demographics as well as questions surrounding perceptions of employer support, work environment, and goal/satisfaction regarding breastfeeding. Data were analyzed via crosstabs and chi-square goodness of fit tests. A total of 1,002 women completed the survey. Significant differences were seen across different employment types. Women within the professional/management industry were most likely to receive informal and direct support for breastfeeding upon return to work. Women within the service industry and production/transportation industry reported receiving the lowest levels of informal and direct support. Workplace support varies by employment type and women in the service and production/transportation industry appear to be at a disadvantage compared with other employment types. There is a need for more breastfeeding support programs to be developed that target specific workplace characteristics.

Search for Dark Matter in events with a hight- pT photon and high missing transverse momentum in ATLAS

NASA Astrophysics Data System (ADS)

Ratti, M. G.

2016-01-01

We present the results of a search for new particles in events with a high-pT photon and high missing transverse momentum with the ATLAS experiment at the LHC. The analysis is performed on the data collected by ATLAS at a centre of mass energy of 8TeV and corresponding to a total integrated luminosity of 20.3 fb-1 . No excess has been found with respect to the Standard Model expectation. A model-independent upper limit on the fiducial cross section for the production of events with a photon and large missing transverse momentum is set. Exclusion limits on the direct pair production of dark matter candidates are presented.

State-resolved differential cross-section measurement of Cl+C 2H 6→HCl+C 2H 5 reaction using single-beam velocity mapping

NASA Astrophysics Data System (ADS)

Samartzis, Peter C.; Smith, Derek J.; Rakitzis, T. Peter; Kitsopoulos, Theofanis N.

2000-07-01

The bimolecular reaction of atomic chlorine with ethane at a collision energy of 0.36 eV is studied in a single-beam experiment, using velocity mapping of a state-selected reaction product. The differential cross-section for HCl( v=0, J=1) product is directly determined from its Abel-inverted velocity map image. Our results are similar to previous measurements of the differential cross-section and suggest that the HCl( v=0, J=1) scattering is broad with a side-scattered peak. This Letter demonstrates the power of velocity mapping for measuring differential cross-sections for reactions for which one of the reactants is produced photolytically.

Wildfire: It's Economic Impact on Grazing Livestock in Northern Nevada

NASA Astrophysics Data System (ADS)

Honeycutt, S.

2015-12-01

As the climate changes and Nevada experiences long severe drought, a key understanding of the economic impacts of wildfire on grazing livestock is essential in the assurance of livestock production in future management of Nevada's rangeland. The focus of this research is to determine the economic impact in the reduction of rangeland available for livestock grazing due to wildfires. The datasets utilized in this research are from 2007 & 2012 and include Bureau of Land Management wildfire, grazing allotments and herd management area geospatial data along with USDA Census of Agriculture, Inventory & Sales Information for cattle & calves, sheep & lambs, and goats. Presented in the results will be the direct, indirect, and induced economic effects of wildfires on rangeland production.

Search for pair production of scalar bottom quarks in pp collisions at square root of s = 1.96 TeV.

PubMed

Abazov, V M; Abbott, B; Abolins, M; Acharya, B S; Adams, M; Adams, T; Agelou, M; Ahn, S H; Ahsan, M; Alexeev, G D; Alkhazov, G; Alton, A; Alverson, G; Alves, G A; Anastasoaie, M; Andeen, T; Anderson, S; Andrieu, B; Anzelc, M S; Arnoud, Y; Arov, M; Askew, A; Asman, B; Jesus, A C S Assis; Atramentov, O; Autermann, C; Avila, C; Ay, C; Badaud, F; Baden, A; Bagby, L; Baldin, B; Bandurin, D V; Banerjee, P; Banerjee, S; Barberis, E; Bargassa, P; Baringer, P; Barnes, C; Barreto, J; Bartlett, J F; Bassler, U; Bauer, D; Bean, A; Begalli, M; Begel, M; Belanger-Champagne, C; Bellantoni, L; Bellavance, A; Benitez, J A; Beri, S B; Bernardi, G; Bernhard, R; Berntzon, L; Bertram, I; Besançon, M; Beuselinck, R; Bezzubov, V A; Bhat, P C; Bhatnagar, V; Binder, M; Biscarat, C; Black, K M; Blackler, I; Blazey, G; Blekman, F; Blessing, S; Bloch, D; Bloom, K; Blumenschein, U; Boehnlein, A; Boeriu, O; Bolton, T A; Borissov, G; Bos, K; Bose, T; Brandt, A; Brock, R; Brooijmans, G; Bross, A; Brown, D; Buchanan, N J; Buchholz, D; Buehler, M; Buescher, V; Burdin, S; Burke, S; Burnett, T H; Busato, E; Buszello, C P; Butler, J M; Calfayan, P; Calvet, S; Cammin, J; Caron, S; Carvalho, W; Casey, B C K; Cason, N M; Castilla-Valdez, H; Chakraborty, D; Chan, K M; Chandra, A; Charles, F; Cheu, E; Chevallier, F; Cho, D K; Choi, S; Choudhary, B; Christofek, L; Claes, D; Clément, B; Clément, C; Coadou, Y; Cooke, M; Cooper, W E; Coppage, D; Corcoran, M; Cousinou, M-C; Cox, B; Crépé-Renaudin, S; Cutts, D; Cwiok, M; da Motta, H; Das, A; Das, M; Davies, B; Davies, G; Davis, G A; De, K; de Jong, P; de Jong, S J; De La Cruz-Burelo, E; De Oliveira Martins, C; Degenhardt, J D; Déliot, F; Demarteau, M; Demina, R; Demine, P; Denisov, D; Denisov, S P; Desai, S; Diehl, H T; Diesburg, M; Doidge, M; Dominguez, A; Dong, H; Dudko, L V; Duflot, L; Dugad, S R; Duggan, D; Duperrin, A; Dyer, J; Dyshkant, A; Eads, M; Edmunds, D; Edwards, T; Ellison, J; Elmsheuser, J; Elvira, V D; Eno, S; Ermolov, P; Evans, H; Evdokimov, A; Evdokimov, V N; Fatakia, S N; Feligioni, L; Ferapontov, A V; Ferbel, T; Fiedler, F; Filthaut, F; Fisher, W; Fisk, H E; Fleck, I; Ford, M; Fortner, M; Fox, H; Fu, S; Fuess, S; Gadfort, T; Galea, C F; Gallas, E; Galyaev, E; Garcia, C; Garcia-Bellido, A; Gardner, J; Gavrilov, V; Gay, A; Gay, P; Gelé, D; Gelhaus, R; Gerber, C E; Gershtein, Y; Gillberg, D; Ginther, G; Gollub, N; Gómez, B; Goussiou, A; Grannis, P D; Greenlee, H; Greenwood, Z D; Gregores, E M; Grenier, G; Gris, Ph; Grivaz, J-F; Grünendahl, S; Grünewald, M W; Guo, F; Guo, J; Gutierrez, G; Gutierrez, P; Haas, A; Hadley, N J; Haefner, P; Hagopian, S; Haley, J; Hall, I; Hall, R E; Han, L; Hanagaki, K; Harder, K; Harel, A; Harrington, R; Hauptman, J M; Hauser, R; Hays, J; Hebbeker, T; Hedin, D; Hegeman, J G; Heinmiller, J M; Heinson, A P; Heintz, U; Hensel, C; Herner, K; Hesketh, G; Hildreth, M D; Hirosky, R; Hobbs, J D; Hoeneisen, B; Hoeth, H; Hohlfeld, M; Hong, S J; Hooper, R; Houben, P; Hu, Y; Hubacek, Z; Hynek, V; Iashvili, I; Illingworth, R; Ito, A S; Jabeen, S; Jaffré, M; Jain, S; Jakobs, K; Jarvis, C; Jenkins, A; Jesik, R; Johns, K; Johnson, C; Johnson, M; Jonckheere, A; Jonsson, P; Juste, A; Käfer, D; Kahn, S; Kajfasz, E; Kalinin, A M; Kalk, J M; Kalk, J R; Kappler, S; Karmanov, D; Kasper, J; Kasper, P; Katsanos, I; Kau, D; Kaur, R; Kehoe, R; Kermiche, S; Khalatyan, N; Khanov, A; Kharchilava, A; Kharzheev, Y M; Khatidze, D; Kim, H; Kim, T J; Kirby, M H; Klima, B; Kohli, J M; Konrath, J-P; Kopal, M; Korablev, V M; Kotcher, J; Kothari, B; Koubarovsky, A; Kozelov, A V; Kozminski, J; Krop, D; Kryemadhi, A; Kuhl, T; Kumar, A; Kunori, S; Kupco, A; Kurca, T; Kvita, J; Lammers, S; Landsberg, G; Lazoflores, J; Le Bihan, A-C; Lebrun, P; Lee, W M; Leflat, A; Lehner, F; Lesne, V; Leveque, J; Lewis, P; Li, J; Li, Q Z; Lima, J G R; Lincoln, D; Linnemann, J; Lipaev, V V; Lipton, R; Liu, Z; Lobo, L; Lobodenko, A; Lokajicek, M; Lounis, A; Love, P; Lubatti, H J; Lynker, M; Lyon, A L; Maciel, A K A; Madaras, R J; Mättig, P; Magass, C; Magerkurth, A; Magnan, A-M; Makovec, N; Mal, P K; Malbouisson, H B; Malik, S; Malyshev, V L; Mao, H S; Maravin, Y; Martens, M; McCarthy, R; Meder, D; Melnitchouk, A; Mendes, A; Mendoza, L; Merkin, M; Merritt, K W; Meyer, A; Meyer, J; Michaut, M; Miettinen, H; Millet, T; Mitrevski, J; Molina, J; Mondal, N K; Monk, J; Moore, R W; Moulik, T; Muanza, G S; Mulders, M; Mulhearn, M; Mundim, L; Mutaf, Y D; Nagy, E; Naimuddin, M; Narain, M; Naumann, N A; Neal, H A; Negret, J P; Neustroev, P; Noeding, C; Nomerotski, A; Novaes, S F; Nunnemann, T; O'Dell, V; O'Neil, D C; Obrant, G; Oguri, V; Oliveira, N; Oshima, N; Otec, R; Y Garzón, G J Otero; Owen, M; Padley, P; Parashar, N; Park, S-J; Park, S K; Parsons, J; Partridge, R; Parua, N; Patwa, A; Pawloski, G; Perea, P M; Perez, E; Peters, K; Pétroff, P; Petteni, M; Piegaia, R; Piper, J; Pleier, M-A; Podesta-Lerma, P L M; Podstavkov, V M; Pogorelov, Y; Pol, M-E; Pompos, A; Pope, B G; Popov, A V; Potter, C; Prado da Silva, W L; Prosper, H B; Protopopescu, S; Qian, J; Quadt, A; Quinn, B; Rangel, M S; Rani, K J; Ranjan, K; Ratoff, P N; Renkel, P; Reucroft, S; Rijssenbeek, M; Ripp-Baudot, I; Rizatdinova, F; Robinson, S; Rodrigues, R F; Royon, C; Rubinov, P; Ruchti, R; Rud, V I; Sajot, G; Sánchez-Hernández, A; Sanders, M P; Santoro, A; Savage, G; Sawyer, L; Scanlon, T; Schaile, D; Schamberger, R D; Scheglov, Y; Schellman, H; Schieferdecker, P; Schmitt, C; Schwanenberger, C; Schwartzman, A; Schwienhorst, R; Sekaric, J; Sengupta, S; Severini, H; Shabalina, E; Shamim, M; Shary, V; Shchukin, A A; Shephard, W D; Shivpuri, R K; Shpakov, D; Siccardi, V; Sidwell, R A; Simak, V; Sirotenko, V; Skubic, P; Slattery, P; Smith, R P; Snow, G R; Snow, J; Snyder, S; Söldner-Rembold, S; Song, X; Sonnenschein, L; Sopczak, A; Sosebee, M; Soustruznik, K; Souza, M; Spurlock, B; Stark, J; Steele, J; Stolin, V; Stone, A; Stoyanova, D A; Strandberg, J; Strandberg, S; Strang, M A; Strauss, M; Ströhmer, R; Strom, D; Strovink, M; Stutte, L; Sumowidagdo, S; Sznajder, A; Talby, M; Tamburello, P; Taylor, W; Telford, P; Temple, J; Tiller, B; Titov, M; Tokmenin, V V; Tomoto, M; Toole, T; Torchiani, I; Towers, S; Trefzger, T; Trincaz-Duvoid, S; Tsybychev, D; Tuchming, B; Tully, C; Turcot, A S; Tuts, P M; Unalan, R; Uvarov, L; Uvarov, S; Uzunyan, S; Vachon, B; van den Berg, P J; Van Kooten, R; van Leeuwen, W M; Varelas, N; Varnes, E W; Vartapetian, A; Vasilyev, I A; Vaupel, M; Verdier, P; Vertogradov, L S; Verzocchi, M; Villeneuve-Seguier, F; Vint, P; Vlimant, J-R; Von Toerne, E; Voutilainen, M; Vreeswijk, M; Wahl, H D; Wang, L; Wang, M H L S; Warchol, J; Watts, G; Wayne, M; Weber, M; Weerts, H; Wermes, N; Wetstein, M; White, A; Wicke, D; Wilson, G W; Wimpenny, S J; Wobisch, M; Womersley, J; Wood, D R; Wyatt, T R; Xie, Y; Xuan, N; Yacoob, S; Yamada, R; Yan, M; Yasuda, T; Yatsunenko, Y A; Yip, K; Yoo, H D; Youn, S W; Yu, C; Yu, J; Yurkewicz, A; Zatserklyaniy, A; Zeitnitz, C; Zhang, D; Zhao, T; Zhou, B; Zhu, J; Zielinski, M; Zieminska, D; Zieminski, A; Zutshi, V; Zverev, E G

2006-10-27

A search for direct production of scalar bottom quarks (b) is performed with 310 pb(-1) of data collected by the D0 experiment in pp collisions at square root s = 1.96 TeV at the Fermilab Tevatron Collider. The topology analyzed consists of two b jets and an imbalance in transverse momentum due to undetected neutralinos (chi(1)0), with chi(1)0 assumed to be the lightest supersymmetric particle. We find the data consistent with standard model expectations, and set a 95% C.L. exclusion domain in the (m(b), m(chi(1)0)) mass plane, improving significantly upon the results from run I of the Tevatron.

Indirect detection of radiation sources through direct detection of radiolysis products

DOEpatents

Farmer, Joseph C [Tracy, CA; Fischer, Larry E [Los Gatos, CA; Felter, Thomas E [Livermore, CA

2010-04-20

A system for indirectly detecting a radiation source by directly detecting radiolytic products. The radiation source emits radiation and the radiation produces the radiolytic products. A fluid is positioned to receive the radiation from the radiation source. When the fluid is irradiated, radiolytic products are produced. By directly detecting the radiolytic products, the radiation source is detected.

Gas-phase reactions of uranate ions, UO(2)(-), UO(3)(-), UO(4)(-), and UO(4)H(-), with methanol: a convergence of experiment and theory.

PubMed

Michelini, Maria Del Carmen; Marçalo, Joaquim; Russo, Nino; Gibson, John K

2010-04-19

Bimolecular reactions of uranium oxide molecular anions with methanol have been studied experimentally, by Fourier transform ion cyclotron resonance mass spectrometry, and computationally, by density functional theory (DFT). The primary goals were to provide fundamental insights into mechanistic and structural details of model reactions of uranium oxides with organics, and to examine the validity of theoretical modeling of these types of reactions. The ions UO(3)(-), UO(4)(-), and UO(4)H(-) each reacted with methanol to give a singular product; the primary products each exhibited sequential reactions with two additional methanol molecules to again give singular products. The observed reactions were elimination of water, formaldehyde, or hydrogen, and in one case addition of a methanol molecule. The potential energy profiles were computed for each reaction, and isotopic labeling experiments were performed to probe the validity of the computed mechanisms and structures-in each case where the experiments could be compared with the theory there was concurrence, clearly establishing the efficacy of the employed DFT methodologies for these and related reaction systems. The DFT results were furthermore in accord with the surprisingly inert nature of UO(2)(-). The results provide a basis to understand mechanisms of key reactions of uranium oxides with organics, and a foundation to extend DFT methodologies to more complex actinide systems which are not amenable to such direct experimental studies.

Effects of environmental variation during seed production on seed dormancy and germination.

PubMed

Penfield, Steven; MacGregor, Dana R

2017-02-01

The environment during seed production has major impacts on the behaviour of progeny seeds. It can be shown that for annual plants temperature perception over the whole life history of the mother can affect the germination rate of progeny, and instances have been documented where these affects cross whole generations. Here we discuss the current state of knowledge of signal transduction pathways controlling environmental responses during seed production, focusing both on events that take place in the mother plant and those that occur directly as a result of environmental responses in the developing zygote. We show that seed production environment effects are complex, involving overlapping gene networks active independently in fruit, seed coat, and zygotic tissues that can be deconstructed using careful physiology alongside molecular and genetic experiments. © The Author 2016. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Design of China Leading Energy Efficiency Program (LEP) for equipment and appliances and comparative study of international experience on super-efficient products

NASA Astrophysics Data System (ADS)

Liang, Xiuying; Zhu, Chunyan

2017-11-01

With rising global emphasizes on climate change and sustainable development, how to accelerate the transformation of energy efficiency has become an important question. Designing and implementing energy-efficiency policies for super-efficient products represents an important direction to achieve breakthroughs in the field of energy conservation. On December 31, 2014, China’s National Development and Reform Commission (NDRC) jointly six other ministerial agencies launched China Leading Energy Efficiency Program (LEP), which identifies top efficiency models for selected product categories. LEP sets the highest energy efficiency benchmark. Design of LEP took into consideration of how to best motivate manufacturers to accelerate technical innovation, promote high efficiency products. This paper explains core elements of LEP, such as objectives, selection criteria, implementation method and supportive policies. It also proposes recommendations to further improve LEP through international policy comparison with Japan’s Top Runner Program, U.S. Energy Star Most Efficient, and SEAD Global Efficiency Medal.

Intracellular Route of Canine Parvovirus Entry

PubMed Central

Vihinen-Ranta, Maija; Kalela, Anne; Mäkinen, Päivi; Kakkola, Laura; Marjomäki, Varpu; Vuento, Matti

1998-01-01

The present study was designed to investigate the endocytic pathway involved in canine parvovirus (CPV) infection. Reduced temperature (18°C) or the microtubule-depolymerizing drug nocodazole was found to inhibit productive infection of canine A72 cells by CPV and caused CPV to be retained in cytoplasmic vesicles as indicated by immunofluorescence microscopy. Consistent with previously published results, these data indicate that CPV enters a host cell via an endocytic route and further suggest that microtubule-dependent delivery of CPV to late endosomes is required for productive infection. Cytoplasmic microinjection of CPV particles was used to circumvent the endocytosis and membrane fusion steps in the entry process. Microinjection experiments showed that CPV particles which were injected directly into the cytoplasm, thus avoiding the endocytic pathway, were unable to initiate progeny virus production. CPV treated at pH 5.0 prior to microinjection was unable to initiate virus production, showing that factors of the endocytic route other than low pH are necessary for the initiation of infection by CPV. PMID:9420290

Adaptation of the xylose fermenting yeast Saccharomyces cerevisiae F12 for improving ethanol production in different fed-batch SSF processes.

PubMed

Tomás-Pejó, E; Ballesteros, M; Oliva, J M; Olsson, L

2010-11-01

An efficient fermenting microorganism for bioethanol production from lignocellulose is highly tolerant to the inhibitors released during pretreatment and is able to ferment efficiently both glucose and xylose. In this study, directed evolution was employed to improve the xylose fermenting Saccharomyces cerevisiae F12 strain for bioethanol production at high substrate loading. Adapted and parental strains were compared with respect to xylose consumption and ethanol production. Adaptation led to an evolved strain more tolerant to the toxic compounds present in the medium. When using concentrated prehydrolysate from steam-pretreated wheat straw with high inhibitor concentration, an improvement of 65 and 20% in xylose consumption and final ethanol concentration, respectively, were achieved using the adapted strain. To address the need of high substrate loadings, fed-batch SSF experiments were performed and an ethanol concentration as high as 27.4 g/l (61% of the theoretical) was obtained with 11.25% (w/w) of water insoluble solids (WIS).

Wastewater recycling technology for fermentation in polyunsaturated fatty acid production.

PubMed

Song, Xiaojin; Ma, Zengxin; Tan, Yanzhen; Zhang, Huidan; Cui, Qiu

2017-07-01

To reduce fermentation-associated wastewater discharge and the cost of wastewater treatment, which further reduces the total cost of DHA and ARA production, this study first analyzed the composition of wastewater from Aurantiochytrium (DHA) and Mortierella alpina (ARA) fermentation, after which wastewater recycling technology for these fermentation processes was developed. No negative effects of DHA and ARA production were observed when the two fermentation wastewater methods were cross-recycled. DHA and ARA yields were significantly inhibited when the wastewater from the fermentation process was directly reused. In 5-L fed-batch fermentation experiments, using this cross-recycle technology, the DHA and ARA yields were 30.4 and 5.13gL -1 , respectively, with no significant changes (P>0.05) compared to the control group, and the water consumption was reduced by half compared to the traditional process. Therefore, this technology has great potential in industrial fermentation for polyunsaturated fatty acid production. Copyright © 2017 Elsevier Ltd. All rights reserved.

Effect of Ion Escape Velocity and Conversion Surface Material on H- Production

NASA Astrophysics Data System (ADS)

Tarvainen, O.; Kalvas, T.; Komppula, J.; Koivisto, H.; Geros, E.; Stelzer, J.; Rouleau, G.; Johnson, K. F.; Carmichael, J.

2011-09-01

According to generally accepted models surface production of negative ions depends on ion escape velocity and work function of the surface. We have conducted an experimental study addressing the role of the ion escape velocity on H- production. A converter-type ion source at Los Alamos Neutron Science Center was employed for the experiment. The ion escape velocity was affected by varying the bias voltage of the converter electrode. It was observed that due to enhanced stripping of H- no direct gain of extracted beam current can be achieved by increasing the converter voltage. The conversion efficiency of H- was observed to vary with converter voltage and follow the existing theories in qualitative manner. We present calculations predicting relative H- yields from different cesiated surfaces with comparison to experimental observations from different types of H- ion sources. Utilizing materials exhibiting negative electron affinity and exposed to UV-light is considered for Cesium-free H-/D- production.

Tribological investigation of oriented HDPE.

PubMed

Hoseini, Mohammed; Lausmaa, Jukka; Boldizar, Antal

2002-09-15

The possibility to control the wear properties of high-density polyethylene (HDPE) material at an early processing stage is explored. Wear measurements of cold roll-drawn HDPE with two different draw ratios were carried out for three sliding planes, each in two directions. The dependence of the wear properties on the degree and direction of orientation was investigated. The experiments were performed in a pin-on-disc machine in a dry environment. The tribo-couple consisted of HDPE plates versus a standardised diamond coated steel disc. The results show that the wear resistance of cold roll-drawn HDPE differ widely, by a factor up to 6, depending on the sliding direction relative to the drawing direction. The material has a significantly better wear resistance when the sliding direction was perpendicular to the processing direction. The best wear resistance was in the end plane and it was improved by a factor up to 3.6 when the draw ratio was increased from 2 to 4. These results indicate that molecular orientation by polymer processing is a promising method to improve the wear properties and decrease the wear debris production of HDPE. Copyright 2002 Wiley Periodicals, Inc.

Origins and Scaling of Hot-Electron Preheat in Ignition-Scale Direct-Drive Inertial Confinement Fusion Experiments.

PubMed

Rosenberg, M J; Solodov, A A; Myatt, J F; Seka, W; Michel, P; Hohenberger, M; Short, R W; Epstein, R; Regan, S P; Campbell, E M; Chapman, T; Goyon, C; Ralph, J E; Barrios, M A; Moody, J D; Bates, J W

2018-02-02

Planar laser-plasma interaction (LPI) experiments at the National Ignition Facility (NIF) have allowed access for the first time to regimes of electron density scale length (∼500 to 700  μm), electron temperature (∼3 to 5 keV), and laser intensity (6 to 16×10^{14}  W/cm^{2}) that are relevant to direct-drive inertial confinement fusion ignition. Unlike in shorter-scale-length plasmas on OMEGA, scattered-light data on the NIF show that the near-quarter-critical LPI physics is dominated by stimulated Raman scattering (SRS) rather than by two-plasmon decay (TPD). This difference in regime is explained based on absolute SRS and TPD threshold considerations. SRS sidescatter tangential to density contours and other SRS mechanisms are observed. The fraction of laser energy converted to hot electrons is ∼0.7% to 2.9%, consistent with observed levels of SRS. The intensity threshold for hot-electron production is assessed, and the use of a Si ablator slightly increases this threshold from ∼4×10^{14} to ∼6×10^{14}  W/cm^{2}. These results have significant implications for mitigation of LPI hot-electron preheat in direct-drive ignition designs.

A Dependence Study of $$\\Xi^{*0}$$ and $$\\bar{\\Xi}^{*0}$$ in 250 GeV/c $$\\pi^-$$. $K^-$ -nucleon Interactions (in Portuguese)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seixas de Rezende, Fabio Antonio; /Rio de Janeiro, CBPF

A direct measurement of the mass number (A) dependence of the production of the hyperon {Xi}*{sup 0} and its opposite {bar {Xi}}*{sup 0} in {pi}{sup -}, K{sup -} beam-nucleon interactions at 250 GeV/c is reported. The data derive from the experiment E769 at Fermilab. The results were obtained for different targets: Be, Al, Cu and W. It was observed the data are found to be well described by the parametrization {sigma}{sub A} = {sigma}{sub 0}A{sup {alpha}}, {alpha} being calculated for different beams. The results obtained are compared with those results of E769 experiment. The results shown here are preliminary.

Quantifying Direct and Indirect Effects of Elevated CO2 on Ecosystem Response

NASA Astrophysics Data System (ADS)

Fatichi, S.; Leuzinger, S.; Paschalis, A.; Donnellan-Barraclough, A.; Hovenden, M. J.; Langley, J. A.

2015-12-01

Increasing concentrations of atmospheric carbon dioxide are expected to affect carbon assimilation, evapotranspiration (ET) and ultimately plant growth. Direct leaf biochemical effects have been widely investigated, while indirect effects, although documented, are very difficult to quantify in experiments. We hypothesize that the interaction of direct and indirect effects is a possible reason for conflicting results concerning the magnitude of CO2 fertilization effects across different climates and ecosystems. A mechanistic ecohydrological model (Tethys-Chloris) is used to investigate the relative contribution of direct (through plant physiology) and indirect (via stomatal closure and thus soil moisture, and changes in Leaf Area Index, LAI) effects of elevated CO2 across a number of ecosystems. We specifically ask in which ecosystems and climate indirect effects are expected to be largest. Data and boundary conditions from flux-towers and free air CO2 enrichment (FACE) experiments are used to force the model and evaluate its performance. Numerical results suggest that indirect effects of elevated CO2, through water savings and increased LAI, are very significant and sometimes larger than direct effects. Indirect effects tend to be considerably larger in water-limited ecosystems, while direct effects correlate positively with mean air temperature. Increasing CO2 from 375 to 550 ppm causes a total effect on Net Primary Production in the order of 15 to 40% and on ET from 0 to -8%, depending on climate and ecosystem type. The total CO2 effect has a significant negative correlation with the wetness index and positive correlation with vapor pressure deficit. These results provide a more general mechanistic understanding of relatively short-term (less than 20 years) implications of elevated CO2 on ecosystem response and suggest plausible magnitudes for the expected changes.

Integration of Nine Steps into One Membrane Reactor To Produce Synthesis Gases for Ammonia and Liquid Fuel.

PubMed

Li, Wenping; Zhu, Xuefeng; Chen, Shuguang; Yang, Weishen

2016-07-18

The synthesis of ammonia and liquid fuel are two important chemical processes in which most of the energy is consumed in the production of H2 /N2 and H2 /CO synthesis gases from natural gas (methane). Here, we report a membrane reactor with a mixed ionic-electronic conducting membrane, in which the nine steps for the production of the two types of synthesis gases are shortened to one step by using water, air, and methane as feeds. In the membrane reactor, there is no direct CO2 emission and no CO or H2 S present in the ammonia synthesis gas. The energy consumption for the production of the two synthesis gases can be reduced by 63 % by using this membrane reactor. This promising membrane reactor process has been successfully demonstrated by experiment. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Nano-Disperse Borides and Carbides: Plasma Technology Production, Specific Properties, Economic Evaluation

NASA Astrophysics Data System (ADS)

Galevskii, G. V.; Rudneva, V. V.; Galevskii, S. G.; Tomas, K. I.; Zubkov, M. S.

2016-04-01

The experience of production and study on properties of nano-disperse chromium and titanium borides and carbides, and silicon carbide has been generalized. The structure and special service aspects of utilized plasma-metallurgical complex equipped with a three-jet direct-flow reactor with a capacity of 150 kW have been outlined. Processing, heat engineering and service life characteristics of the reactor are specified. The synthesis parameters of borides and carbides, as well as their basic characteristics in nano-disperse condition and their production flow diagram are outlined. Engineering and economic performance of synthesizing borides in laboratory and industrial conditions is assessed, and the respective segment of the international market as well. The work is performed at State Siberian Industrial University as a project part of the State Order of Ministry of Science and Education of the Russian Federation No. 11.1531/2014/K.

Report on ISS Oxygen Production, Resupply, and Partial Pressure Management

NASA Technical Reports Server (NTRS)

Schaezler, Ryan; Ghariani, Ahmed; Leonard, Daniel; Lehman, Daniel

2011-01-01

The majority of oxygen used on International Space Station (ISS) is for metabolic support and denitrogenation procedures prior to Extra-Vehicular Activities. Oxygen is supplied by various visiting vehicles such as the Progress and Shuttle in addition to oxygen production capability on both the United States On-Orbit Segment (USOS) and Russian Segment (RS). To maintain a habitable atmosphere the oxygen partial pressure is controlled between upper and lower bounds. The full range of the allowable oxygen partial pressure along with the increased ISS cabin volume is utilized as a buffer allowing days to pass between oxygen production or direct addition of oxygen to the atmosphere from reserves. This paper summarizes amount of oxygen supplied and produced from all of the sources and describes past experience of managing oxygen partial pressure along with the range of management options available to the ISS.

[Establishment of traceability system of Chinese medicinal materials' quality].

PubMed

Qi, Yao-dong; Gao, Shi-man; Liu, Hai-tao; Li, Xi-wen; Wei, Jian-he; Zhang, Ben-gang; Sun, Xiao-bo; Xiao, Pei-gen

2015-12-01

The quality of Chinese medicinal materials relates greatly to the clinical curative effect and security. In order to ensure the quality and safety of Chinese medicinal materials, a systematic and operable traceability system needs to be established. It can realize the whole process of quality and safety management of Chinese medicinal materials "from production to consumption" through recording and inquiring information and recalling defective products, which is an important direction for the future development of traditional Chinese medicine. But it is still at the exploration and trial stage. In this paper, a framework of Chinese medicinal materials' quality and safety traceability system was established on the basis of the domestic and international experience about the construction of food and agricultural products traceability systems. The relationship between traceability system of Chinese medicinal materials' quality and GAP, GMP, GSP was analyzed, and the possible problems and the corresponding solutions were discussed.

Comparison of different two-pathway models for describing the combined effect of DO and nitrite on the nitrous oxide production by ammonia-oxidizing bacteria.

PubMed

Lang, Longqi; Pocquet, Mathieu; Ni, Bing-Jie; Yuan, Zhiguo; Spérandio, Mathieu

2017-02-01

The aim of this work is to compare the capability of two recently proposed two-pathway models for predicting nitrous oxide (N 2 O) production by ammonia-oxidizing bacteria (AOB) for varying ranges of dissolved oxygen (DO) and nitrite. The first model includes the electron carriers whereas the second model is based on direct coupling of electron donors and acceptors. Simulations are confronted to extensive sets of experiments (43 batches) from different studies with three different microbial systems. Despite their different mathematical structures, both models could well and similarly describe the combined effect of DO and nitrite on N 2 O production rate and emission factor. The model-predicted contributions for nitrifier denitrification pathway and hydroxylamine pathway also matched well with the available isotopic measurements. Based on sensitivity analysis, calibration procedures are described and discussed for facilitating the future use of those models.

Product design enhancement using apparent usability and affective quality.

PubMed

Seva, Rosemary R; Gosiaco, Katherine Grace T; Santos, Ma Crea Eurice D; Pangilinan, Denise Mae L

2011-03-01

In this study, apparent usability and affective quality were integrated in a design framework called the Usability Perception and Emotion Enhancement Model (UPEEM). The UPEEM was validated using structural equation modeling (SEM). The methodology consists of four phases namely product selection, attribute identification, design alternative generation, and design alternative evaluation. The first stage involved the selection of a product that highly involves the consumer. In the attribute identification stage, design elements of the product were identified. The possible values of these elements were also determined for use in the experimentation process. Design of experiments was used to identify how the attributes will be varied in the design alternative stage and which of the attributes significantly contribute to affective quality, apparent usability, and desirability in the design evaluation stage. Results suggest that product attributes related to form are relevant in eliciting intense affect and perception of usability in mobile phones especially those directly related to functionality and aesthetics. This study considered only four product attributes among so many due to the constraints of the research design employed. Attributes related to aesthetic perception of a product enhance apparent usability such as those related to dimensional ratios. Copyright © 2010 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Retrieval attempts enhance learning regardless of time spent trying to retrieve.

PubMed

Vaughn, Kalif E; Hausman, Hannah; Kornell, Nate

2017-03-01

Attempting to retrieve information from memory is an engaging cognitive activity. We predicted that people would learn more when they had spent more time attempting to retrieve. In experiments 1a and 1b, participants were shown trivia questions for 0, 5, 10, or 30 seconds and then the answer was revealed. They took a final test immediately or after 48 hours. Retrieval enhanced learning, but the length of the retrieval attempt had no effect (i.e., final test performance was equivalent in the 5-, 10-, and 30-second conditions and worse in the 0-second condition). During the initial retrieval attempt, more time did increase recall, suggesting that participants continued to engage in productive retrieval activities when given more time. Showing the answer for longer (7 versus 2 seconds) increased learning in Experiments 2a and 2b. Experiment 3 examined the effect of retrieval success and Experiment 4 replicated the results using different materials. These results have direct implications for current theories of retrieval.

Masked syllable priming effects in word and picture naming in Chinese.

PubMed

You, Wenping; Zhang, Qingfang; Verdonschot, Rinus G

2012-01-01

Four experiments investigated the role of the syllable in Chinese spoken word production. Chen, Chen and Ferrand (2003) reported a syllable priming effect when primes and targets shared the first syllable using a masked priming paradigm in Chinese. Our Experiment 1 was a direct replication of Chen et al.'s (2003) Experiment 3 employing CV (e.g., ,/ba2.ying2/, strike camp) and CVG (e.g., ,/bai2.shou3/, white haired) syllable types. Experiment 2 tested the syllable priming effect using different syllable types: e.g., CV (,/qi4.qiu2/, balloon) and CVN (,/qing1.ting2/, dragonfly). Experiment 3 investigated this issue further using line drawings of common objects as targets that were preceded either by a CV (e.g., ,/qi3/, attempt), or a CVN (e.g., ,/qing2/, affection) prime. Experiment 4 further examined the priming effect by a comparison between CV or CVN priming and an unrelated priming condition using CV-NX (e.g., ,/mi2.ni3/, mini) and CVN-CX (e.g., ,/min2.ju1/, dwellings) as target words. These four experiments consistently found that CV targets were named faster when preceded by CV primes than when they were preceded by CVG, CVN or unrelated primes, whereas CVG or CVN targets showed the reverse pattern. These results indicate that the priming effect critically depends on the match between the structure of the prime and that of the first syllable of the target. The effect obtained in this study was consistent across different stimuli and different tasks (word and picture naming), and provides more conclusive and consistent data regarding the role of the syllable in Chinese speech production.

Images of trauma: pain, recognition, and disavowal in the works of Frida Kahlo and Francis Bacon.

PubMed

Bose, Joerg

2005-01-01

The role of art in the encounter with trauma and destructiveness is comparatively studied in the works of Frida Kahlo and Francis Bacon as examples of a direct and a more indirect way of dealing with such experiences. A creative product may function intrapsychically as a kind of messenger between dissociated self-states and consciousness, and it may also serve as a witnessing presence in a self-supporting and self-constituting way. Artistic work may thus be used by the artist for an expressive as well as for a protective purpose, as a means of sympathetic participation in painful experience, or as a medium for a view from the outside. The act itself of finding and of making expressive forms at the time of traumatic experience is a remarkable assertion of the human capability to synthesize and to counteract fragmenting dissociative processes.

Corrosion Behavior of Steels in Supercritical CO 2 for Power Cycle Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Repukaiti, Richard; Teeter, Lucas; Ziomek-Moroz, Margaret

In order to understand issues with corrosion of heat exchanger materials in direct supercritical carbon dioxide (sCO 2) power cycles, a series of autoclave exposure experiments and electrochemical experiments have been conducted. Corrosion behaviors of 347H stainless steel and P91 martensitic-ferrtic steel in sCO 2 environment have been compared. In autoclave exposure tests performed at 50°C- 245°C and 80 bar. Mass change measurements, surface characterization, and corrosion product analysis have been conducted to understand the corrosion behavior of steels in sCO 2 containing H 2O and O 2. Electrochemical tests performed at room temperature and 50°C, a simulation environment ofmore » water condensation phase with dissolved CO 2 was prepared to evaluate the corrosion resistance of materials. From both types of experiments, generally 347H showed higher corrosion resistance than P91.« less

An effective and optimal quality control approach for green energy manufacturing using design of experiments framework and evolutionary algorithm

NASA Astrophysics Data System (ADS)

Saavedra, Juan Alejandro

Quality Control (QC) and Quality Assurance (QA) strategies vary significantly across industries in the manufacturing sector depending on the product being built. Such strategies range from simple statistical analysis and process controls, decision-making process of reworking, repairing, or scraping defective product. This study proposes an optimal QC methodology in order to include rework stations during the manufacturing process by identifying the amount and location of these workstations. The factors that are considered to optimize these stations are cost, cycle time, reworkability and rework benefit. The goal is to minimize the cost and cycle time of the process, but increase the reworkability and rework benefit. The specific objectives of this study are: (1) to propose a cost estimation model that includes energy consumption, and (2) to propose an optimal QC methodology to identify quantity and location of rework workstations. The cost estimation model includes energy consumption as part of the product direct cost. The cost estimation model developed allows the user to calculate product direct cost as the quality sigma level of the process changes. This provides a benefit because a complete cost estimation calculation does not need to be performed every time the processes yield changes. This cost estimation model is then used for the QC strategy optimization process. In order to propose a methodology that provides an optimal QC strategy, the possible factors that affect QC were evaluated. A screening Design of Experiments (DOE) was performed on seven initial factors and identified 3 significant factors. It reflected that one response variable was not required for the optimization process. A full factorial DOE was estimated in order to verify the significant factors obtained previously. The QC strategy optimization is performed through a Genetic Algorithm (GA) which allows the evaluation of several solutions in order to obtain feasible optimal solutions. The GA evaluates possible solutions based on cost, cycle time, reworkability and rework benefit. Finally it provides several possible solutions because this is a multi-objective optimization problem. The solutions are presented as chromosomes that clearly state the amount and location of the rework stations. The user analyzes these solutions in order to select one by deciding which of the four factors considered is most important depending on the product being manufactured or the company's objective. The major contribution of this study is to provide the user with a methodology used to identify an effective and optimal QC strategy that incorporates the number and location of rework substations in order to minimize direct product cost, and cycle time, and maximize reworkability, and rework benefit.

Visualizing Cloud Properties and Satellite Imagery: A Tool for Visualization and Information Integration

NASA Astrophysics Data System (ADS)

Chee, T.; Nguyen, L.; Smith, W. L., Jr.; Spangenberg, D.; Palikonda, R.; Bedka, K. M.; Minnis, P.; Thieman, M. M.; Nordeen, M.

2017-12-01

Providing public access to research products including cloud macro and microphysical properties and satellite imagery are a key concern for the NASA Langley Research Center Cloud and Radiation Group. This work describes a web based visualization tool and API that allows end users to easily create customized cloud product and satellite imagery, ground site data and satellite ground track information that is generated dynamically. The tool has two uses, one to visualize the dynamically created imagery and the other to provide access to the dynamically generated imagery directly at a later time. Internally, we leverage our practical experience with large, scalable application practices to develop a system that has the largest potential for scalability as well as the ability to be deployed on the cloud to accommodate scalability issues. We build upon NASA Langley Cloud and Radiation Group's experience with making real-time and historical satellite cloud product information, satellite imagery, ground site data and satellite track information accessible and easily searchable. This tool is the culmination of our prior experience with dynamic imagery generation and provides a way to build a "mash-up" of dynamically generated imagery and related kinds of information that are visualized together to add value to disparate but related information. In support of NASA strategic goals, our group aims to make as much scientific knowledge, observations and products available to the citizen science, research and interested communities as well as for automated systems to acquire the same information for data mining or other analytic purposes. This tool and the underlying API's provide a valuable research tool to a wide audience both as a standalone research tool and also as an easily accessed data source that can easily be mined or used with existing tools.

When is an image a health claim? A false-recollection method to detect implicit inferences about products' health benefits.

PubMed

Klepacz, Naomi A; Nash, Robert A; Egan, M Bernadette; Hodgkins, Charo E; Raats, Monique M

2016-08-01

Images on food and dietary supplement packaging might lead people to infer (appropriately or inappropriately) certain health benefits of those products. Research on this issue largely involves direct questions, which could (a) elicit inferences that would not be made unprompted, and (b) fail to capture inferences made implicitly. Using a novel memory-based method, in the present research, we explored whether packaging imagery elicits health inferences without prompting, and the extent to which these inferences are made implicitly. In 3 experiments, participants saw fictional product packages accompanied by written claims. Some packages contained an image that implied a health-related function (e.g., a brain), and some contained no image. Participants studied these packages and claims, and subsequently their memory for seen and unseen claims were tested. When a health image was featured on a package, participants often subsequently recognized health claims that-despite being implied by the image-were not truly presented. In Experiment 2, these recognition errors persisted despite an explicit warning against treating the images as informative. In Experiment 3, these findings were replicated in a large consumer sample from 5 European countries, and with a cued-recall test. These findings confirm that images can act as health claims, by leading people to infer health benefits without prompting. These inferences appear often to be implicit, and could therefore be highly pervasive. The data underscore the importance of regulating imagery on product packaging; memory-based methods represent innovative ways to measure how leading (or misleading) specific images can be. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Limits to the Positive Effect of Ocean Acidification on Macroalgal Primary Production, Interactions with Light and Temperature

NASA Astrophysics Data System (ADS)

Kubler, J.; Dudgeon, S. R.; Nisumaa, A. M.

2016-02-01

About one third of macroalgal species lack any carbon concentrating mechanism (CCM), which prevents carbon limitation under air equilibrium in other seaweed species. It is predicted that those species lacking CCM's will benefit from ongoing ocean acidification in terms of primary productivity and growth. The absolute sizes and pattern of those benefits are not known. Here, we compare the results of a model based on composite data from the literature, with a growth experiment using Plocamium cartilagineum, a broadly distributed rhodophyte species lacking a carbon concentrating mechanism and hypothesized to be carbon limited under current conditions. We grew P. cartilagineum, at 15 and 20°C in seawater aerated with a total of 53 different pCO2s (from 344 to 1053µatm), in 8 multiweek trials over 12 months. We measured growth and photosynthetic rates. A linear mixed model analysis was used to partition the effect sizes of drivers of variation in the experiment. The growth rates and maximum photosynthetic rates responded nonlinearly to OA, increasing with elevated pCO2 from recent atmospheric level to up 450µatm and decreasing at higher pCO2. Light harvesting efficiency was unaffected by pCO2 and inversely related to temperature. We were able to compare the results of the growth experiment directly to the model based on the additive effects of temperature and pCO2 on photosynthetic rates, finding concordance of the pattern of response. The size of the effect of pCO2 on growth rate in the experiment was greater than the effect predicted by the model for net primary productivity. These results predict that the benefit of OA for macroalgal growth may disappear as ocean acidification continues through this century.

Application of open-path Fourier transform infrared spectroscopy for atmospheric monitoring of a CO2 back-production experiment at the Ketzin pilot site (Germany).

PubMed

Sauer, Uta; Borsdorf, H; Dietrich, P; Liebscher, A; Möller, I; Martens, S; Möller, F; Schlömer, S; Schütze, C

2018-02-03

During a controlled "back-production experiment" in October 2014 at the Ketzin pilot site, formerly injected CO 2 was retrieved from the storage formation and directly released to the atmosphere via a vent-off stack. Open-path Fourier transform infrared (OP FTIR) spectrometers, on-site meteorological parameter acquisition systems, and distributed CO 2 point sensors monitored gas dispersion processes in the near-surface part of the atmospheric boundary layer. The test site provides a complex and challenging mosaic-like surface setting for atmospheric monitoring which can also be found at other storage sites. The main aims of the atmospheric monitoring of this experiment were (1) to quantify temporal and spatial variations in atmospheric CO 2 concentrations around the emitting vent-off stack and (2) to test if and how atmospheric monitoring can cope with typical environmental and operational challenges. A low environmental risk was encountered during the whole CO 2 back-production experiment. The study confirms that turbulent wind conditions favor atmospheric mixing processes and are responsible for rapid dilution of the released CO 2 leading to decreased detectability at all sensors. In contrast, calm and extremely stable wind conditions (especially occurring during the night) caused an accumulation of gases in the near-ground atmospheric layer with the highest amplitudes in measured gas concentration. As an important benefit of OP FTIR spectroscopic measurements and their ability to detect multiple gas species simultaneously, emission sources could be identified to a much higher certainty. Moreover, even simulation models using simplified assumptions help to find suitable monitoring network designs and support data analysis for certain wind conditions in such a complex environment.

Effects of Degree of Curing on Fire Spread

NASA Astrophysics Data System (ADS)

Chaivaranont, W.; Evans, J. P.; Liu, Y.

2016-12-01

During extreme summer conditions in Australia, bushfire can become an uncontrollable natural hazard. Various factors, such as geographical and meteorological parameters greatly influence the magnitude of bushfire. In a grassland fire, there is an important factor that affects the severity of fire called the degree of curing. Degree of curing is a percentage measurement of the proportion of dead material in grassland where a 100% curing indicates a totally dead grass field. It is usually assumed constant due to the cost and difficulty in obtaining accurate field observations.To examine the importance of curing, the Phoenix RapidFire fire spread model was used to observe the magnitude and direction of grassland fire spread due to variations in the degree of curing. Idealised experiments and experiments based on 3 past fire events in Australia were conducted, where the 100 by 200 km study area is considered to be all grassland. In the idealised experiments, homogeneous curing data in various patterns were used along with extreme climate data and prescribed topography. In the past fire event experiments, satellite-derived estimated curing data, observed climate data from the nearest weather stations, and real elevation maps were used. A remotely sensed burned area map (MODIS MCD64A1 product) is also used to compare the simulated burned area of past fire events with the satellite observation.The results from both experiments showed that: 1) the rate of spread of grassland fire is significantly impeded when curing is below 75%, 2) topography has insignificant effect on fire spread direction and speed, 3) wind and curing both influence the direction and speed of spread, and 4) the model can only recreate the burned area in one out of three of the past fire events due to various causes including the fact that all past events used here were not exclusively grassland fire.

Direct and precise measurement of displacement and velocity of flexible web in roll-to-roll manufacturing systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kang, Dongwoo; Lee, Eonseok; Choi, Young-Man

Interest in the production of printed electronics using a roll-to-roll system has gradually increased due to its low mass-production costs and compatibility with flexible substrate. To improve the accuracy of roll-to-roll manufacturing systems, the movement of the web needs to be measured precisely in advance. In this paper, a novel measurement method is developed to measure the displacement and velocity of the web precisely and directly. The proposed algorithm is based on the traditional single field encoder principle, and the scale grating has been replaced with a printed grating on the web. Because a printed grating cannot be as accuratemore » as a scale grating in a traditional encoder, there will inevitably be variations in pitch and line-width, and the motion of the web should be measured even though there are variations in pitch and line-width in the printed grating patterns. For this reason, the developed algorithm includes a precise method of estimating the variations in pitch. In addtion, a method of correcting the Lissajous curve is presented for precision phase interpolation to improve measurement accuracy by correcting Lissajous circle to unit circle. The performance of the developed method is evaluated by simulation and experiment. In the experiment, the displacement error was less than 2.5 μm and the velocity error of 1σ was about 0.25%, while the grating scale moved 30 mm.« less

Direct and precise measurement of displacement and velocity of flexible web in roll-to-roll manufacturing systems

NASA Astrophysics Data System (ADS)

Kang, Dongwoo; duk Kim, Young; Lee, Eonseok; Choi, Young-Man; Lee, Taik-Min; Kim, Dongmin

2013-12-01

Interest in the production of printed electronics using a roll-to-roll system has gradually increased due to its low mass-production costs and compatibility with flexible substrate. To improve the accuracy of roll-to-roll manufacturing systems, the movement of the web needs to be measured precisely in advance. In this paper, a novel measurement method is developed to measure the displacement and velocity of the web precisely and directly. The proposed algorithm is based on the traditional single field encoder principle, and the scale grating has been replaced with a printed grating on the web. Because a printed grating cannot be as accurate as a scale grating in a traditional encoder, there will inevitably be variations in pitch and line-width, and the motion of the web should be measured even though there are variations in pitch and line-width in the printed grating patterns. For this reason, the developed algorithm includes a precise method of estimating the variations in pitch. In addtion, a method of correcting the Lissajous curve is presented for precision phase interpolation to improve measurement accuracy by correcting Lissajous circle to unit circle. The performance of the developed method is evaluated by simulation and experiment. In the experiment, the displacement error was less than 2.5 μm and the velocity error of 1σ was about 0.25%, while the grating scale moved 30 mm.

Investigating the mechanism of clofibric acid removal in Fe(0)/H2O systems.

PubMed

Ghauch, Antoine; Abou Assi, Hala; Tuqan, Almuthanna

2010-04-15

Since the introduction of iron wall technology, the inherent relationship between contaminant removal and iron corrosion has been mostly attributed to electron transfer from the metal body (direct reduction). This thermodynamically founded premise has failed to explain several experimental facts. Recently, a new concept considering adsorption and co-precipitation as fundamental contaminant removal mechanisms was introduced. This consistent concept has faced very skeptic views and necessarily needs experimental validation. The present work was the first independent attempt to validate the new concept using clofibric acid (CLO) as model compound. For this purpose, a powdered Fe(0) material (Fe(0)) was used in CLO removal experiments under various experimental conditions. Additional experiments were performed with plated Fe(0) (mFe(0): Fe(0)/Pd(0), Fe(0)/Ni(0)) to support the discussion of removal mechanism. Main investigated experimental variables included: abundance of O(2), abundance of iron corrosion products (ICPs) and shaking operations. Results corroborated the concept that quantitative contaminant removal in Fe(0)/H(2)O systems occurs within the oxide-film in the vicinity of Fe(0). Additionally, mixing type and shaking intensity significantly influenced the extent of CLO removal. More importantly, HPLC/MS revealed that the identity of reaction products depends on the extent of iron corrosion or the abundance of ICPs. The investigation of the CLO/Fe(0)/H(2)O system disproved the popular view that direct reduction mediates contaminant removal in the presence of Fe(0). 2009 Elsevier B.V. All rights reserved.

Observing a light dark matter beam with neutrino experiments

NASA Astrophysics Data System (ADS)

Deniverville, Patrick; Pospelov, Maxim; Ritz, Adam

2011-10-01

We consider the sensitivity of fixed-target neutrino experiments at the luminosity frontier to light stable states, such as those present in models of MeV-scale dark matter. To ensure the correct thermal relic abundance, such states must annihilate via light mediators, which in turn provide an access portal for direct production in colliders or fixed targets. Indeed, this framework endows the neutrino beams produced at fixed-target facilities with a companion “dark matter beam,” which may be detected via an excess of elastic scattering events off electrons or nuclei in the (near-)detector. We study the high-luminosity proton fixed-target experiments at LSND and MiniBooNE, and determine that the ensuing sensitivity to light dark matter generally surpasses that of other direct probes. For scenarios with a kinetically-mixed U(1)' vector mediator of mass mV, we find that a large volume of parameter space is excluded for mDM˜1-5MeV, covering vector masses 2mDM≲mV≲mη and a range of kinetic mixing parameters reaching as low as κ˜10-5. The corresponding MeV-scale dark matter scenarios motivated by an explanation of the galactic 511 keV line are thus strongly constrained.

Direct Dark Matter Detection through the use of a Xenon Based TPC Detector

NASA Astrophysics Data System (ADS)

Daniel, Jonathan; Akerib, Daniel; LZ group at SLAC

2018-01-01

The vast majority of matter in the universe is unaccounted for. Only 15% of the universe's mass density is visible matter, while the other 85% is Dark Matter (DM). The Weakly Interacting Massive Particle (WIMP) is currently the frontrunner of the DM candidates. The Large Underground Xenon (LUX) and next generation LUX-ZEPLIN (LZ) experiments are designed to directly detect WIMPs. Both experiments are xenon-based Time Projection Chambers (TPC) used to observe possible WIMP interactions. These interactions produce photons and electrons with the photons being collected in a set of two photomultiplier tube (PMT) arrays and the electrons drifted upwards in the detector by a strong electric field to create a secondary production of photons in gaseous xenon. These two populations of photons are classified as S1 and S2 signals, respectively. Using these signals we reconstruct the energy and position of the interaction and in doing so we can eliminate background events that would otherwise “light up” the detector. My participation in the experiment, while at SLAC, was the creation of the grids that produce the large electric field, along with additional lab activities aimed at testing the grids. While at Stan State, I work on background modeling in order to distinguish a possible WIMP signal from ambient backgrounds.

Search for direct top squark pair production in final states with two tau leptons in pp collisions at √s = 8  TeV with the ATLAS detector

DOE PAGES

Aad, G.; Abbott, B.; Abdallah, J.; ...

2016-02-16

A search for direct pair production of the supersymmetric partner of the top quark, decaying via a scalar tau to a nearly massless gravitino, has been performed using 20 fb -1 of proton–proton collision data at √s = 8 TeV . The data were collected by the ATLAS experiment at the LHC in 2012. Top squark candidates are searched for in events with either two hadronically decaying tau leptons, one hadronically decaying tau and one light lepton, or two light leptons. No significant excess over the Standard Model expectation is found. Exclusion limits at 95% confidence level are set asmore » a function of the top squark and scalar tau masses. As a result, depending on the scalar tau mass, ranging from the 87 GeV LEP limit to the top squark mass, lower limits between 490 and 650 GeV are placed on the top squark mass within the model considered.« less

Evolution and dynamics of shear-layer structures in near-wall turbulence

NASA Technical Reports Server (NTRS)

Johansson, Arne V.; Alfredsson, P. H.; Kim, John

1991-01-01

Near-wall flow structures in turbulent shear flows are analyzed, with particular emphasis on the study of their space-time evolution and connection to turbulence production. The results are obtained from investigation of a database generated from direct numerical simulation of turbulent channel flow at a Reynolds number of 180 based on half-channel width and friction velocity. New light is shed on problems associated with conditional sampling techniques, together with methods to improve these techniques, for use both in physical and numerical experiments. The results clearly indicate that earlier conceptual models of the processes associated with near-wall turbulence production, based on flow visualization and probe measurements need to be modified. For instance, the development of asymmetry in the spanwise direction seems to be an important element in the evolution of near-wall structures in general, and for shear layers in particular. The inhibition of spanwise motion of the near-wall streaky pattern may be the primary reason for the ability of small longitudinal riblets to reduce turbulent skin friction below the value for a flat surface.

Production of ZrC Matrix for Use in Gas Fast Reactor Composite Fuels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vasudevamurthy, Gokul; Knight, Travis W.; Roberts, Elwyn

2007-07-01

Zirconium carbide is being considered as a candidate for inert matrix material in composite nuclear fuel for Gas fast reactors due to its favorable characteristics. ZrC can be produced by the direct reaction of pure zirconium and graphite powders. Such a reaction is exothermic in nature. The reaction is self sustaining once initial ignition has been achieved. The heat released during the reaction is high enough to complete the reaction and achieve partial sintering without any external pressure applied. External heat source is required to achieve ignition of the reactants and maintain the temperature close to the adiabatic temperature tomore » achieve higher levels of sintering. External pressure is also a driving force for sintering. In the experiments described, cylindrical compacts of ZrC were produced by direct combustion reaction. External induction heating combined with varying amounts of external applied pressure was employed to achieve varying degrees of density/porosity. The effect of reactant particle size on the product characteristics was also studied. The samples were characterized for density/porosity, composition and microstructure. (authors)« less

A Numerical Model for Two-Plasmon-Decay Hot-Electron Production and Mitigation in Direct-Drive Implosions

NASA Astrophysics Data System (ADS)

Myatt, J. F.; Shaw, J. G.; Solodov, A. A.; Maximov, A. V.; Short, R. W.; Seka, W.; Follett, R. K.; Edgell, D. H.; Froula, D. H.; Goncharov, V. N.

2015-11-01

Hot-electron preheat, caused by laser-plasma instabilities, can impair the performance of inertial confinement fusion implosions. It is therefore imperative to understand processes that can generate hot electrons and to design mitigation strategies should preheat be found to be excessive at the ignition scale (laser-plasma interactions do not follow hydrodynamic scaling). For this purpose, a new 3-D model [laser-plasma simulation environment (LPSE)] has been constructed that computes hot-electron generation in direct-drive plasmas based on the assumption that two-plasmon decay is the dominant, hot-electron-producing instability. It uses an established model of TPD-driven turbulence together with a new GPU based hybrid particle method of hot-electron production. The time-dependent hot-electron power, total energy, and energy spectrum are computed and compared with data from recent OMEGA implosion experiments that have sought to mitigate TPD by the use of multilayered (mid- Z) ablators. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

Measuring the impact of computer resource quality on the software development process and product

NASA Technical Reports Server (NTRS)

Mcgarry, Frank; Valett, Jon; Hall, Dana

1985-01-01

The availability and quality of computer resources during the software development process was speculated to have measurable, significant impact on the efficiency of the development process and the quality of the resulting product. Environment components such as the types of tools, machine responsiveness, and quantity of direct access storage may play a major role in the effort to produce the product and in its subsequent quality as measured by factors such as reliability and ease of maintenance. During the past six years, the NASA Goddard Space Flight Center has conducted experiments with software projects in an attempt to better understand the impact of software development methodologies, environments, and general technologies on the software process and product. Data was extracted and examined from nearly 50 software development projects. All were related to support of satellite flight dynamics ground-based computations. The relationship between computer resources and the software development process and product as exemplified by the subject NASA data was examined. Based upon the results, a number of computer resource-related implications are provided.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoo, Hojin

The thesis presents studies of vacuum pair productions and its applications in early universe cosmology and high energy astrophysics. Vacuum often becomes unstable and spontaneously decays into pairs of particles in rapidly expanding universes or under strong external electromagnetic fields. Theoretically, spontaneous pair productions due to such non-trivial backgrounds of spacetimes or electromagnetic fields are well-understood. However, the effect of particle productions has not been observed so far because of experiemtal difficulties in obtaining large curvatures of space-times or strong electric fields. Although it may be impossible to observe the pair productions directly via laboratory experiments, there are still powerfulmore » sources of space-time curvatures or electric fields in cosmology and astrophysics, which result in observations. In Part I, we explore the inflationary models in early universe utilizing pair productions through gravity. We study observable signatures on the cosmic microwave background, such as isocurvature perturbations and non-Gaussianities, generated from the particle production of WIMPzillas and axions during or after inflation. In Part II, we investigate the electron-positron pair production in the magnetosphere of pulsars whose electromagnetic fields are expected to close to or even greater than the pair production threshold. In particular, we demonstrate that the pair production may be responsible for giant pulses from the Crab pulsar.« less

Modelling of Coke Layer Collapse during Ore Charging in Ironmaking Blast Furnace by DEM

NASA Astrophysics Data System (ADS)

Narita, Yoichi; Mio, Hiroshi; Orimoto, Takashi; Nomura, Seiji

2017-06-01

A technical issue in an ironmaking blast furnace operation is to realize the optimum layer thickness and the radial distribution of burden (ore and coke) to enhance its efficiency and productivity. When ore particles are charged onto the already-embedded coke layer, the coke layer-collapse phenomenon occurs. The coke layer-collapse phenomenon has a significant effect on the distribution of ore and coke layer thickness in the radial direction. In this paper, the mechanical properties of coke packed bed under ore charging were investigated by the impact-loading test and the large-scale direct shear test. Experimental results show that the coke particle is broken by the impact force of ore charging, and the particle breakage leads to weaken of coke-layer strength. The expression of contact force for coke in Discrete Element Method (DEM) was modified based on the measured data, and it followed by the 1/3-scaled experiment on coke's collapse phenomena. Comparing a simulation by modified model to the 1/3-scaled experiment, they agreed well in the burden distribution.

Dynamic exit-channel pathways of the microsolvated HOO-(H2O) + CH3Cl SN2 reaction: Reaction mechanisms at the atomic level from direct chemical dynamics simulations

NASA Astrophysics Data System (ADS)

Yu, Feng

2018-01-01

Microsolvated bimolecular nucleophilic substitution (SN2) reaction of monohydrated hydrogen peroxide anion [HOO-(H2O)] with methyl chloride (CH3Cl) has been investigated with direct chemical dynamics simulations at the M06-2X/6-31+G(d,p) level of theory. Dynamic exit-channel pathways and corresponding reaction mechanisms at the atomic level are revealed in detail. Accordingly, a product distribution of 0.85:0.15 is obtained for Cl-:Cl-(H2O), which is consistent with a previous experiment [D. L. Thomsen et al. J. Am. Chem. Soc. 135, 15508 (2013)]. Compared with the HOO- + CH3Cl SN2 reaction, indirect dynamic reaction mechanisms are enhanced by microsolvation for the HOO-(H2O) + CH3Cl SN2 reaction. On the basis of our simulations, further crossed molecular beam imaging experiments are highly suggested for the SN2 reactions of HOO- + CH3Cl and HOO-(H2O) + CH3Cl.

Dynamic exit-channel pathways of the microsolvated HOO-(H2O) + CH3Cl SN2 reaction: Reaction mechanisms at the atomic level from direct chemical dynamics simulations.

PubMed

Yu, Feng

2018-01-07

Microsolvated bimolecular nucleophilic substitution (S N 2) reaction of monohydrated hydrogen peroxide anion [HOO - (H 2 O)] with methyl chloride (CH 3 Cl) has been investigated with direct chemical dynamics simulations at the M06-2X/6-31+G(d,p) level of theory. Dynamic exit-channel pathways and corresponding reaction mechanisms at the atomic level are revealed in detail. Accordingly, a product distribution of 0.85:0.15 is obtained for Cl - :Cl - (H 2 O), which is consistent with a previous experiment [D. L. Thomsen et al. J. Am. Chem. Soc. 135, 15508 (2013)]. Compared with the HOO - + CH 3 Cl S N 2 reaction, indirect dynamic reaction mechanisms are enhanced by microsolvation for the HOO - (H 2 O) + CH 3 Cl S N 2 reaction. On the basis of our simulations, further crossed molecular beam imaging experiments are highly suggested for the S N 2 reactions of HOO - + CH 3 Cl and HOO - (H 2 O) + CH 3 Cl.

Operational experience of the OC-OTEC experiments at NELH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Link, H

1989-02-01

The Solar Energy Research Institute, under funding and program direction from the US Department of Energy, has been operating a small-scale test apparatus to investigate key components of open- cycle ocean thermal energy conversion (OC-OTEC). The apparatus started operations in October 1987 and continues to provide valuable information on heat-and mass-transfer processes in evaporators and condensers, gas sorption processes as seawater is depressurized and repressurized, and control and instrumentation characteristics of open-cycle systems. Although other test facilities have been used to study some of these interactions, this is the largest apparatus of its kind to use seawater since Georges Claude`smore » efforts in 1926. The information obtained from experiments conducted in this apparatus is being used to design a larger scale experiment in which a positive net power production is expected to be demonstrated for the first time with OC-OTEC. This paper describes the apparatus, the major tests conducted during its first 18 months of operation, and the experience gained in OC-OTEC system operation. 13 refs., 8 figs.« less

Amaro-autonomous real-time detection of moving maritime objects: introducing a flight experiment for an on-board ship detection system

NASA Astrophysics Data System (ADS)

Schwenk, Kurt; Willburger, Katharina; Pless, Sebastian

2017-10-01

Motivated by politics and economy, the monitoring of the world wide ship traffic is a field of high topicality. To detect illegal activities like piracy, illegal fishery, ocean dumping and refugee transportation is of great value. The analysis of satellite images on the ground delivers a great contribution to situation awareness. However, for many applications the up-to-dateness of the data is crucial. With ground based processing, the time between image acquisition and delivery of the data to the end user is in the range of several hours. The highest influence to the duration of ground based processing is the delay caused by the transmission of the large amount of image data from the satellite to the processing centre on the ground. One expensive solution to this issue is the usage of data relay satellites systems like EDRS. Another approach is to analyse the image data directly on-board of the satellite. Since the product data (e.g. ship position, heading, velocity, characteristics) is very small compared to the input image data, real-time connections provided by satellite telecommunication services like Iridium or Orbcomm can be used to send small packets of information directly to the end user without significant delay. The AMARO (Autonomous real-time detection of moving maritime objects) project at DLR is a feasibility study of an on-board ship detection system involving a real-time low bandwidth communication. The operation of a prototype on-board ship detection system will be demonstrated on an airborne platform. In this article, the scope, aim and design of a flight experiment for an on-board ship detection system scheduled for mid of 2018 is presented. First, the scope and the constraints of the experiment are explained in detail. The main goal is to demonstrate the operability of an automatic ship detection system on board of an airplane. For data acquisition the optical high resolution DLR MACS-MARE camera (VIS/NIR) is used. The system will be able to send product data, like position, size and a small image of the ship directly to the user's smart-phone by email. The time between the acquisition of the image data and the delivery of the product data to the end-user is aimed to be less than three minutes. For communication, the SMS-like Iridium Short Burst Data (SBD) Service was chosen, providing a message size of around 300 Bytes. Under optimal sending/receiving conditions, messages can be transmitted bidirectional every 20 seconds. Due to the very small data bandwidth, not all product data may be transmittable at once, for instance, when flying over busy ships traffic zones. Therefore the system offers two services: a query and a push service. With the query service the end user can explicitly request data of a defined location and fixed time period by posting queries in an SQL-like language. With the push service, events can be predefined and messages are received automatically, if and when the event occurs. Finally, the hardware set-up, details of the ship detection algorithms and the current status of the experiment is presented.

Sequestration of flue gas CO₂ by direct gas-solid carbonation of air pollution control system residues.

PubMed

Tian, Sicong; Jiang, Jianguo

2012-12-18

Direct gas-solid carbonation reactions of residues from an air pollution control system (APCr) were conducted using different combinations of simulated flue gas to study the impact on CO₂ sequestration. X-ray diffraction analysis of APCr determined the existence of CaClOH, whose maximum theoretical CO₂ sequestration potential of 58.13 g CO₂/kg APCr was calculated by the reference intensity ratio method. The reaction mechanism obeyed a model of a fast kinetics-controlled process followed by a slow product layer diffusion-controlled process. Temperature is the key factor in direct gas-solid carbonation and had a notable influence on both the carbonation conversion and the CO₂ sequestration rate. The optimal CO₂ sequestrating temperature of 395 °C was easily obtained for APCr using a continuous heating experiment. CO₂ content in the flue gas had a definite influence on the CO₂ sequestration rate of the kinetics-controlled process, but almost no influence on the final carbonation conversion. Typical concentrations of SO₂ in the flue gas could not only accelerate the carbonation reaction rate of the product layer diffusion-controlled process, but also could improve the final carbonation conversion. Maximum carbonation conversions of between 68.6% and 77.1% were achieved in a typical flue gas. Features of rapid CO₂ sequestration rate, strong impurities resistance, and high capture conversion for direct gas-solid carbonation were proved in this study, which presents a theoretical foundation for the applied use of this encouraging technology on carbon capture and storage.

Energy-Efficient and Environmentally Friendly Solid Oxide Membrane Electrolysis Process for Magnesium Oxide Reduction: Experiment and Modeling

NASA Astrophysics Data System (ADS)

Guan, Xiaofei; Pal, Uday B.; Powell, Adam C.

2014-06-01

This paper reports a solid oxide membrane (SOM) electrolysis experiment using an LSM(La0.8Sr0.2MnO3-δ)-Inconel inert anode current collector for production of magnesium and oxygen directly from magnesium oxide at 1423 K (1150 °C). The electrochemical performance of the SOM cell was evaluated by means of various electrochemical techniques including electrochemical impedance spectroscopy, potentiodynamic scan, and electrolysis. Electronic transference numbers of the flux were measured to assess the magnesium dissolution in the flux during SOM electrolysis. The effects of magnesium solubility in the flux on the current efficiency and the SOM stability during electrolysis are discussed. An inverse correlation between the electronic transference number of the flux and the current efficiency of the SOM electrolysis was observed. Based on the experimental results, a new equivalent circuit of the SOM electrolysis process is presented. A general electrochemical polarization model of SOM process for magnesium and oxygen gas production is developed, and the maximum allowable applied potential to avoid zirconia dissociation is calculated as well. The modeling results suggest that a high electronic resistance of the flux and a relatively low electronic resistance of SOM are required to achieve membrane stability, high current efficiency, and high production rates of magnesium and oxygen.

Management of complaints in blood establishments: thirteen years of experience at the Croatian Institute of Transfusion Medicine.

PubMed

Vuk, Tomislav; Barišić, Marijan; Očić, Tihomir; Đogić, Vesna; Bingulac-Popović, Jasna; Sarlija, Dorotea; Balija, Melita; Jukić, Irena

2012-07-01

The aim of the study is to present the results and experience in the management of complaints in a transfusion service in order to draw attention to the importance of this segment of quality management and to stimulate publication of other studies on the topic. This study is based on data from the Croatian Institute of Transfusion Medicine obtained by analysis of complaints recorded during a 13-year period (1998-2010). The distribution of the types and frequencies of complaints is presented, along with the level of their justifiability and criticality. The dynamics of the complaints is analysed overall and within particular categories. In addition, corrective actions and other factors that may have influenced the trends observed are discussed. During the study period, 817 complaints were received, most of which (40.9%) referred to the positive direct antiglobulin test in red cell concentrates, followed by blood product issuing and distribution (12.9%) and blood product quality (9.4%). Of the 817 complaints, 177 (21.7%) were assessed as serious and 645 (78.9%) as justified based on the testing performed. Data collected by systematic recording and analysis of complaints provide a basis for problem identification, implementation of corrective and preventive actions, and improvement of product and service quality, and, thereby, customer satisfaction.

Effect of lignocellulose-derived inhibitors on the growth and D-lactic acid production of Sporolactobacillus inulinus YBS1-5.

PubMed

Bai, Zhongzhong; Gao, Zhen; He, Bingfang; Wu, Bin

2015-10-01

The impact of lignocellulose-derived inhibitors on the cell growth and D-lactic production of Sporolactobacillus inulinus YBS1-5 was investigated. At high concentrations, both furans and phenolics, such as furfural, HMF, syringaldehyde and vanillin, affected cell growth and D-lactic acid production and syringaldehyde exhibited the highest. Further experiments showed that only vanillin caused cellular membrane damage. Based on the Biolog approach, in vivo studies on intact S. inulinus cells indicated that phenolics had a stronger inhibitory effect than furan derivatives on the metabolic activity of the concerned substrates related with the key enzymes of D-lactic acid fermentation. The direct in vitro inhibitory effect of the model compounds on the four key enzymes displayed similar patterns. Syringaldehyde was the strongest inhibitor. In general, comparison with published results for other microorganisms indicated that strain YBS1-5 was a robust microorganism against inhibitors of lignocellulose hydrolysate. Notably, in concentrated corn stover hydrolysate, S. inulinus YBS1-5 produced 70.7 g/L D-lactic acid, which was 87.7 % of the yield from the control experiment. However, the fermentation time was prolonged 36 h. In order to improve fermentation rate, a detoxification technology or more robust mutant to phenolics especially syringaldehyde should be developed.

A smart Monte Carlo procedure for production costing and uncertainty analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parker, C.; Stremel, J.

1996-11-01

Electric utilities using chronological production costing models to decide whether to buy or sell power over the next week or next few weeks need to determine potential profits or losses under a number of uncertainties. A large amount of money can be at stake--often $100,000 a day or more--and one party of the sale must always take on the risk. In the case of fixed price ($/MWh) contracts, the seller accepts the risk. In the case of cost plus contracts, the buyer must accept the risk. So, modeling uncertainty and understanding the risk accurately can improve the competitive edge ofmore » the user. This paper investigates an efficient procedure for representing risks and costs from capacity outages. Typically, production costing models use an algorithm based on some form of random number generator to select resources as available or on outage. These algorithms allow experiments to be repeated and gains and losses to be observed in a short time. The authors perform several experiments to examine the capability of three unit outage selection methods and measures their results. Specifically, a brute force Monte Carlo procedure, a Monte Carlo procedure with Latin Hypercube sampling, and a Smart Monte Carlo procedure with cost stratification and directed sampling are examined.« less

Biodiversity and ecosystem stability in a decade-long grassland experiment.

PubMed

Tilman, David; Reich, Peter B; Knops, Johannes M H

2006-06-01

Human-driven ecosystem simplification has highlighted questions about how the number of species in an ecosystem influences its functioning. Although biodiversity is now known to affect ecosystem productivity, its effects on stability are debated. Here we present a long-term experimental field test of the diversity-stability hypothesis. During a decade of data collection in an experiment that directly controlled the number of perennial prairie species, growing-season climate varied considerably, causing year-to-year variation in abundances of plant species and in ecosystem productivity. We found that greater numbers of plant species led to greater temporal stability of ecosystem annual aboveground plant production. In particular, the decadal temporal stability of the ecosystem, whether measured with intervals of two, five or ten years, was significantly greater at higher plant diversity and tended to increase as plots matured. Ecosystem stability was also positively dependent on root mass, which is a measure of perenniating biomass. Temporal stability of the ecosystem increased with diversity, despite a lower temporal stability of individual species, because of both portfolio (statistical averaging) and overyielding effects. However, we found no evidence of a covariance effect. Our results indicate that the reliable, efficient and sustainable supply of some foods (for example, livestock fodder), biofuels and ecosystem services can be enhanced by the use of biodiversity.

Optimization of a high-yield, low-areal-density fusion product source at the National Ignition Facility with applications in nucleosynthesis experiments

NASA Astrophysics Data System (ADS)

Gatu Johnson, M.; Casey, D. T.; Hohenberger, M.; Zylstra, A. B.; Bacher, A.; Brune, C. R.; Bionta, R. M.; Craxton, R. S.; Ellison, C. L.; Farrell, M.; Frenje, J. A.; Garbett, W.; Garcia, E. M.; Grim, G. P.; Hartouni, E.; Hatarik, R.; Herrmann, H. W.; Hohensee, M.; Holunga, D. M.; Hoppe, M.; Jackson, M.; Kabadi, N.; Khan, S. F.; Kilkenny, J. D.; Kohut, T. R.; Lahmann, B.; Le, H. P.; Li, C. K.; Masse, L.; McKenty, P. W.; McNabb, D. P.; Nikroo, A.; Parham, T. G.; Parker, C. E.; Petrasso, R. D.; Pino, J.; Remington, B.; Rice, N. G.; Rinderknecht, H. G.; Rosenberg, M. J.; Sanchez, J.; Sayre, D. B.; Schoff, M. E.; Shuldberg, C. M.; Séguin, F. H.; Sio, H.; Walters, Z. B.; Whitley, H. D.

2018-05-01

Polar-direct-drive exploding pushers are used as a high-yield, low-areal-density fusion product source at the National Ignition Facility with applications including diagnostic calibration, nuclear security, backlighting, electron-ion equilibration, and nucleosynthesis-relevant experiments. In this paper, two different paths to improving the performance of this platform are explored: (i) optimizing the laser drive, and (ii) optimizing the target. While the present study is specifically geared towards nucleosynthesis experiments, the results are generally applicable. Example data from T2/3He-gas-filled implosions with trace deuterium are used to show that yield and ion temperature (Tion) from 1.6 mm-outer-diameter thin-glass-shell capsule implosions are improved at a set laser energy by switching from a ramped to a square laser pulse shape, and that increased laser energy further improves yield and Tion, although by factors lower than predicted by 1 D simulations. Using data from D2/3He-gas-filled implosions, yield at a set Tion is experimentally verified to increase with capsule size. Uniform D3He-proton spectra from 3 mm-outer-diameter CH shell implosions demonstrate the utility of this platform for studying charged-particle-producing reactions relevant to stellar nucleosynthesis.

Optimization of a high-yield, low-areal-density fusion product source at the National Ignition Facility with applications in nucleosynthesis experiments

DOE PAGES

Gatu Johnson, M.; Casey, D. T.; Hohenberger, M.; ...

2018-05-09

Polar-direct-drive exploding pushers are used as a high-yield, low-areal-density fusion product source at the National Ignition Facility with applications including diagnostic calibration, nuclear security, backlighting, electron-ion equilibration, and nucleosynthesis-relevant experiments. In this paper, two different paths to improving the performance of this platform are explored: (i) optimizing the laser drive, and (ii) optimizing the target. While the present study is specifically geared towards nucleosynthesis experiments, the results are generally applicable. Example data from T 2/ 3He-gas-filled implosions with trace deuterium are used to show that yield and ion temperature (Tion) from 1.6 mm-outer-diameter thin-glass-shell capsule implosions are improved at amore » set laser energy by switching from a ramped to a square laser pulse shape, and that increased laser energy further improves yield and Tion, although by factors lower than predicted by 1 D simulations. Using data from D2-3He-gas-filled implosions, yield at a set Tion is experimentally verified to increase with capsule size. Uniform D-3He-proton spectra from 3 mm-outer-diameter CH shell implosions demonstrate the utility of this platform for studying charged-particle-producing reactions relevant to stellar nucleosynthesis.« less

Optimization of a high-yield, low-areal-density fusion product source at the National Ignition Facility with applications in nucleosynthesis experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gatu Johnson, M.; Casey, D. T.; Hohenberger, M.

Polar-direct-drive exploding pushers are used as a high-yield, low-areal-density fusion product source at the National Ignition Facility with applications including diagnostic calibration, nuclear security, backlighting, electron-ion equilibration, and nucleosynthesis-relevant experiments. In this paper, two different paths to improving the performance of this platform are explored: (i) optimizing the laser drive, and (ii) optimizing the target. While the present study is specifically geared towards nucleosynthesis experiments, the results are generally applicable. Example data from T 2/ 3He-gas-filled implosions with trace deuterium are used to show that yield and ion temperature (Tion) from 1.6 mm-outer-diameter thin-glass-shell capsule implosions are improved at amore » set laser energy by switching from a ramped to a square laser pulse shape, and that increased laser energy further improves yield and Tion, although by factors lower than predicted by 1 D simulations. Using data from D2-3He-gas-filled implosions, yield at a set Tion is experimentally verified to increase with capsule size. Uniform D-3He-proton spectra from 3 mm-outer-diameter CH shell implosions demonstrate the utility of this platform for studying charged-particle-producing reactions relevant to stellar nucleosynthesis.« less

What have we learned from global change manipulative experiments in China? A meta-analysis

PubMed Central

Fu, Zheng; Niu, Shuli; Dukes, Jeffrey S.

2015-01-01

Although China has the largest population in the world, a faster rate of warming than the global average, and an active global change research program, results from many of the global change experiments in Chinese terrestrial ecosystems have not been included in global syntheses. Here, we specifically analyze the observed responses of carbon (C) and nitrogen (N) cycling in global change manipulative experiments in China, and compare these responses to those from other regions of the world. Most global change factors, vegetation types, and treatment methods that have been studied or used elsewhere in the world have also been studied and applied in China. The responses of terrestrial ecosystem C and N cycles to N addition and climate warming in China are similar in both direction and intensity to those reported in global syntheses. In Chinese ecosystems as elsewhere, N addition significantly increased aboveground (AGB) and belowground biomass (BGB), litter mass, dissolved organic C, net ecosystem productivity (NEP), and gross ecosystem productivity (GEP). Warming stimulated AGB, BGB and the root-shoot ratio. Increasing precipitation accelerated GEP, NEP, microbial respiration, soil respiration, and ecosystem respiration. Our findings complement and support previous global syntheses and provide insight into regional responses to global change. PMID:26205333

Intercomparison and validation of MODIS and GLASS leaf area index (LAI) products over mountain areas: A case study in southwestern China

NASA Astrophysics Data System (ADS)

Jin, Huaan; Li, Ainong; Bian, Jinhu; Nan, Xi; Zhao, Wei; Zhang, Zhengjian; Yin, Gaofei

2017-03-01

The validation study of leaf area index (LAI) products over rugged surfaces not only gives additional insights into data quality of LAI products, but deepens understanding of uncertainties regarding land surface process models depended on LAI data over complex terrain. This study evaluated the performance of MODIS and GLASS LAI products using the intercomparison and direct validation methods over southwestern China. The spatio-temporal consistencies, such as the spatial distributions of LAI products and their statistical relationship as a function of topographic indices, time, and vegetation types, respectively, were investigated through intercomparison between MODIS and GLASS products during the period 2011-2013. The accuracies and change ranges of these two products were evaluated against available LAI reference maps over 10 sampling regions which standed for typical vegetation types and topographic gradients in southwestern China. The results show that GLASS LAI exhibits higher percentage of good quality data (i.e. successful retrievals) and smoother temporal profiles than MODIS LAI. The percentage of successful retrievals for MODIS and GLASS is vulnerable to topographic indices, especially to relief amplitude. Besides, the two products do not capture seasonal dynamics of crop, especially in spring over heterogeneously hilly regions. The yearly mean LAI differences between MODIS and GLASS are within ±0.5 for 64.70% of the total retrieval pixels over southwestern China. The spatial distribution of mean differences and temporal profiles of these two products are inclined to be dominated by vegetation types other than topographic indices. The spatial and temporal consistency of these two products is good over most area of grasses/cereal crops; however, it is poor for evergreen broadleaf forest. MODIS presents more reliable change range of LAI than GLASS through comparison with fine resolution reference maps over most of sampling regions. The accuracies of direct validation are obtained for GLASS LAI (r = 0.35, RMSE = 1.72, mean bias = -0.71) and MODIS LAI (r = 0.49, RMSE = 1.75, mean bias = -0.67). GLASS performs similarly to MODIS, but may be marginally inferior to MODIS based on our direct validation results. The validation experience demonstrates the necessity and importance of topographic consideration for LAI estimation over mountain areas. Considerable attention will be paid to the improvements of surface reflectance, retrieval algorithm and land cover types so as to enhance the quality of LAI products in topographically complex terrain.

Direct and Indirect Harassment Experiences and Burnout among Academic Faculty in Japan.

PubMed

Takeuchi, Masumi; Nomura, Kyoko; Horie, Saki; Okinaga, Hiroko; Perumalswami, Chithra R; Jagsi, Reshma

2018-05-01

The purpose of this study is three-fold: (1) to compare harassment (sexual, gender, and academic harassment both directly and indirectly experienced - i.e. "directly harassed" and "have seen or heard of someone who experienced harassment", respectively) experienced by males and females, (2) to investigate whether such experiences correlate with burnout, and (3) to explore whether social support might mitigate any such relationship between harassment and burnout. This cross-sectional study was conducted at a private university in Japan in February 2014 and is based on a work-life balance survey obtained from 330 academic faculty members. We investigated the association between each of the six subcategories of harassment (direct and indirect forms of each of the three types) and burnout using general linear regression models; we then evaluated interactions between harassment and social support in these models. The prevalence of direct and indirect experiences of harassment was higher in females than in males for all three types of harassment. Males showed higher burnout scores if they had direct experiences of harassment. There were significant interactions between social support and the direct experience of harassment; high social support mitigated the effect size of direct harassment on burnout among males. Females showed higher burnout scores if they had indirect experiences of harassment. However, the same buffering effect of social support on burnout as observed in males was not observed in females. Direct harassment experiences increased the risk of burnout in males, and indirect harassment experiences increased burnout in females.

A mixed-method examination of food marketing directed towards children in Australian supermarkets.

PubMed

Campbell, Sarah; James, Erica L; Stacey, Fiona G; Bowman, Jennifer; Chapman, Kathy; Kelly, Bridget

2014-06-01

The purpose of this study was to determine the prevalence of children's food requests, and parents' experiences of food marketing directed towards children, in the supermarket environment. A mixed-method design was used. Firstly, intercept interviews were conducted with parents accompanied by a child/children on exiting supermarkets (sampled from a large regional centre in Australia). Parents were asked about the prevalence and types of food requests by child/children during their supermarket visit and whether they purchased these foods. Secondly, focus groups (n = 13) and telephone interviews (n = 3) were conducted exploring parents' experiences of supermarket shopping with children and the impact of child-directed marketing. Of the 158 intercept survey participants (30% response rate), 73% reported a food request during the supermarket visit. Most requested food items (88%) were unhealthy foods, with chocolate/confectionery being the most common food category requested (40%). Most parents (70%) purchased at least one food item requested during the shopping trip. Qualitative interviews identified four themes associated with food requests and prompts in the supermarket: parents' experience of pester power in the supermarket; prompts for food requests in the supermarket; parental responses to pestering in the supermarket environment, and; strategies to manage pestering and minimize requests for food items. Food requests from children are common during supermarket shopping. Despite the majority of the requests being unhealthy, parents often purchase these foods. Parents reported difficulties dealing with constant requests and expressed desire for environmental changes including confectionery-free checkouts, minimization of child friendly product placement and reducing children's exposure to food marketing.

Directed differentiation of embryonic stem cells using a bead-based combinatorial screening method.

PubMed

Tarunina, Marina; Hernandez, Diana; Johnson, Christopher J; Rybtsov, Stanislav; Ramathas, Vidya; Jeyakumar, Mylvaganam; Watson, Thomas; Hook, Lilian; Medvinsky, Alexander; Mason, Chris; Choo, Yen

2014-01-01

We have developed a rapid, bead-based combinatorial screening method to determine optimal combinations of variables that direct stem cell differentiation to produce known or novel cell types having pre-determined characteristics. Here we describe three experiments comprising stepwise exposure of mouse or human embryonic cells to 10,000 combinations of serum-free differentiation media, through which we discovered multiple novel, efficient and robust protocols to generate a number of specific hematopoietic and neural lineages. We further demonstrate that the technology can be used to optimize existing protocols in order to substitute costly growth factors with bioactive small molecules and/or increase cell yield, and to identify in vitro conditions for the production of rare developmental intermediates such as an embryonic lymphoid progenitor cell that has not previously been reported.

Microfabricated polymer injector for direct mass spectrometry coupling.

PubMed

Gobry, Véronique; van Oostrum, Jan; Martinelli, Marco; Rohner, Tatiana C; Reymond, Frédéric; Rossier, Joël S; Girault, Hubert H

2002-04-01

This paper demonstrates the coupling of a plasma etched polymer microfluidic system with an electrospray mass spectrometer by generation of a nanospray. Taking advantage of the microtechnology processes and polymer properties, high volume production with good reproducibility of hydrophobic interfaces could be obtained. The nanospray was directly produced from the outlet of the plastic microfabricated chip positioned in front of the capillary entrance of the mass spectrometer. No chemical background due to the polymer has been observed under standard nanospray conditions. The performances of the spray as well as its efficiency have been demonstrated by flow measurements, stability establishment and tandem mass spectrometry experiment on angiotensin II. The spray was actuated without additional flow in methanol: water:acetic acid (50:49:1%) solution. A 40 fmol/microL detection limit could be reached.

Paul Trapping of Radioactive {sup 6}He{sup +} Ions and Direct Observation of Their {beta} Decay

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flechard, X.; Lienard, E.; Mery, A.

2008-11-21

We demonstrate that abundant quantities of short-lived {beta} unstable ions can be trapped in a novel transparent Paul trap and that their decay products can directly be detected in coincidence. Low energy {sup 6}He{sup +} (807 ms half-life) ions were extracted from the SPIRAL source at GANIL, then decelerated, cooled, and bunched by means of the buffer gas cooling technique. More than 10{sup 8} ions have been stored over a measuring period of six days, and about 10{sup 5} decay coincidences between the beta particles and the {sup 6}Li{sup ++} recoiling ions have been recorded. The technique can be extendedmore » to other short-lived species, opening new possibilities for trap assisted decay experiments.« less

Dynamical Disentangling and Cooling of Atoms in Bilayer Optical Lattices

NASA Astrophysics Data System (ADS)

Kantian, A.; Langer, S.; Daley, A. J.

2018-02-01

We show how experimentally available bilayer lattice systems can be used to prepare quantum many-body states with exceptionally low entropy in one layer, by dynamically disentangling the two layers. This disentangling operation moves one layer—subsystem A —into a regime where excitations in A develop a single-particle gap. As a result, this operation maps directly to cooling for subsystem A , with entropy being shuttled to the other layer. For both bosonic and fermionic atoms, we study the corresponding dynamics showing that disentangling can be realized cleanly in ongoing experiments. The corresponding entanglement entropies are directly measurable with quantum gas microscopes, and, as a tool for producing lower-entropy states, this technique opens a range of applications beginning with simplifying production of magnetically ordered states of bosons and fermions.

A table top experiment to investigate production and properties of a plasma confined by a dipole magnet

NASA Astrophysics Data System (ADS)

Baitha, Anuj Ram; Kumar, Ashwani; Bhattacharjee, Sudeep

2018-02-01

We report a table top experiment to investigate production and properties of a plasma confined by a dipole magnet. A water cooled, strong, cylindrical permanent magnet (NdFeB) magnetized along the axial direction and having a surface magnetic field of ˜0.5 T is employed to create a dipole magnetic field. The plasma is created by electron cyclotron resonance heating. Visual observations of the plasma indicate that radiation belts appear due to trapped particles, similar to the earth's magnetosphere. The electron temperature lies in the range 2-13 eV and is hotter near the magnets and in a downstream region. It is found that the plasma (ion) density reaches a value close to 2 × 1011 cm-3 and peaks at a radial distance about 3 cm from the magnet. The plasma beta β (β = plasma pressure/magnetic pressure) increases radially outward, and the maximum β for the present experimental system is ˜2%. It is also found that the singly charged ions are dominant in the discharge.

ThermoData Engine (TDE): software implementation of the dynamic data evaluation concept. 5. Experiment planning and product design.

PubMed

Diky, Vladimir; Chirico, Robert D; Kazakov, Andrei F; Muzny, Chris D; Magee, Joseph W; Abdulagatov, Ilmutdin; Kang, Jeong Won; Kroenlein, Kenneth; Frenkel, Michael

2011-01-24

ThermoData Engine (TDE) is the first full-scale software implementation of the dynamic data evaluation concept, as reported recently in this journal. In the present paper, we describe development of an algorithmic approach to assist experiment planning through assessment of the existing body of knowledge, including availability of experimental thermophysical property data, variable ranges studied, associated uncertainties, state of prediction methods, and parameters for deployment of prediction methods and how these parameters can be obtained using targeted measurements, etc., and, indeed, how the intended measurement may address the underlying scientific or engineering problem under consideration. A second new feature described here is the application of the software capabilities for aid in the design of chemical products through identification of chemical systems possessing desired values of thermophysical properties within defined ranges of tolerance. The algorithms and their software implementation to achieve this are described. Finally, implementation of a new data validation and weighting system is described for vapor-liquid equilibrium (VLE) data, and directions for future enhancements are outlined.

Selective One-Dimensional Total Correlation Spectroscopy Nuclear Magnetic Resonance Experiments for a Rapid Identification of Minor Components in the Lipid Fraction of Milk and Dairy Products: Toward Spin Chromatography?

PubMed

Papaemmanouil, Christina; Tsiafoulis, Constantinos G; Alivertis, Dimitrios; Tzamaloukas, Ouranios; Miltiadou, Despoina; Tzakos, Andreas G; Gerothanassis, Ioannis P

2015-06-10

We report a rapid, direct, and unequivocal spin-chromatographic separation and identification of minor components in the lipid fraction of milk and common dairy products with the use of selective one-dimensional (1D) total correlation spectroscopy (TOCSY) nuclear magnetic resonance (NMR) experiments. The method allows for the complete backbone spin-coupling network to be elucidated even in strongly overlapped regions and in the presence of major components from 4 × 10(2) to 3 × 10(3) stronger NMR signal intensities. The proposed spin-chromatography method does not require any derivatization steps for the lipid fraction, is selective with excellent resolution, is sensitive with quantitation capability, and compares favorably to two-dimensional (2D) TOCSY and gas chromatography-mass spectrometry (GC-MS) methods of analysis. The results of the present study demonstrated that the 1D TOCSY NMR spin-chromatography method can become a procedure of primary interest in food analysis and generally in complex mixture analysis.

SuperCDMS Underground Detector Fabrication Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Platt, M.; Mahapatra, R.; Bunker, Raymond A.

The SuperCDMS SNOLAB dark matter experiment processes Ge and Si crystals into fully tested phonon and ionization detectors at surface fabrication and test facilities. If not mitigated, it is anticipated that trace-level production of radioisotopes in the crystals due to exposure to cosmic rays at (or above) sea level will result in the dominant source of background events in future dark matter searches using the current SuperCDMS detector technology. Fabrication and testing of detectors in underground facilities shielded from cosmic radiation is one way to directly reduce production of trace levels of radioisotopes, thereby improving experimental sensitivity for the discoverymore » of dark matter beyond the level of the current experiment. In this report, we investigate the cost and feasibility to establish a complete detector fabrication processing chain in an underground location to mitigate cosmogenic activation of the Ge and Si detector substrates. For a specific and concrete evaluation, we explore options for such a facility located at SNOLAB, an underground laboratory in Sudbury, Canada hosting the current and future experimental phases of SuperCDMS.« less

Inferring difficulty: Flexibility in the real-time processing of disfluency

PubMed Central

Heller, Daphna; Arnold, Jennifer E.; Klein, Natalie M.; Tanenhaus, Michael K.

2015-01-01

Upon hearing a disfluent referring expression, listeners expect the speaker to refer to an object that is previously-unmentioned, an object that does not have a straightforward label, or an object that requires a longer description. Two visual-world eye-tracking experiments examined whether listeners directly associate disfluency with these properties of objects, or whether disfluency attribution is more flexible and involves situation-specific inferences. Since in natural situations reference to objects that do not have a straightforward label or that require a longer description is correlated with both production difficulty and with disfluency, we used a mini artificial lexicon to dissociate difficulty from these properties, building on the fact that recently-learned names take longer to produce than existing words in one’s mental lexicon. The results demonstrate that disfluency attribution involves situation-specific inferences; we propose that in new situations listeners spontaneously infer what may cause production difficulty. However, the results show that these situation-specific inferences are limited in scope: listeners assessed difficulty relative to their own experience with the artificial names, and did not adapt to the assumed knowledge of the speaker. PMID:26677642

Coca (Erythroxylum coca) Control is Affected by Glyphosate Formulations and Adjuvants.

PubMed

Marshall, E J P; Solomon, Keith R; Carrasquilla, Gabriel

2009-01-01

The aerial spray program for the eradication of coca in Colombia uses Glyphos, a local formulation of glyphosate tank-mixed with an adjuvant product, Cosmo-Flux. There are some potential risks to amphibians from direct overspraying of shallow waters. In order to evaluate potential alternative mixtures, a field experiment was conducted at the Center of National Training of Police Operations in Tolima province, Colombia. Plants of coca were established with irrigation and grown to 75 cm tall. A randomized split-plot design experiment was laid out and sprayed with a range of glyphosate formulations and different adjuvants using an experimental ground sprayer. Assessments were made of plant vigor, height, and above-ground standing crop (fresh weight) 3 wk after application. Resprouting of plants was assessed at 9 wk after treatment. Unformulated glyphosate applied as the product Rodeo gave poorer control of coca than two formulated products, Roundup Biactive (from Europe) and Colombian Glyphos. In general, these products performed well without added adjuvants, giving control similar to that of the eradication mixture with Cosmo-Flux. There was some evidence that addition of the adjuvant Silwet L-77 and to a lesser extent Mixture B (from the United Kingdom) gave more rapid herbicide symptoms. There were also indications that glyphosate rates of less than 3.69 kg acid equivalents (a.e.)/ha could give control in the range of 95%. Depending on the environmental risk requirements, the experiment indicates that, should other spray mixtures be required, there are potential alternatives. These would require extensive field testing to cover different environmental conditions, different coca varieties, and particularly aerial application, prior to a recommendation. Should the glyphosate product require changing, Roundup Biactive may be considered. Should the adjuvant require changing, then on the basis of this research, Silwet L-77 and Mixture B would be good candidates for further evaluation.

Asymmetric responses of primary productivity to precipitation extremes: A synthesis of grassland precipitation manipulation experiments

DOE PAGES

Wilcox, Kevin R.; Shi, Zheng; Gherardi, Laureano A.; ...

2017-04-02

Climatic changes are altering Earth's hydrological cycle, resulting in altered precipitation amounts, increased interannual variability of precipitation, and more frequent extreme precipitation events. These trends will likely continue into the future, having substantial impacts on net primary productivity (NPP) and associated ecosystem services such as food production and carbon sequestration. Frequently, experimental manipulations of precipitation have linked altered precipitation regimes to changes in NPP. Yet, findings have been diverse and substantial uncertainty still surrounds generalities describing patterns of ecosystem sensitivity to altered precipitation. Additionally, we do not know whether previously observed correlations between NPP and precipitation remain accurate when precipitationmore » changes become extreme. We synthesized results from 83 case studies of experimental precipitation manipulations in grasslands worldwide. Here, we used meta-analytical techniques to search for generalities and asymmetries of aboveground NPP (ANPP) and belowground NPP (BNPP) responses to both the direction and magnitude of precipitation change. Sensitivity (i.e., productivity response standardized by the amount of precipitation change) of BNPP was similar under precipitation additions and reductions, but ANPP was more sensitive to precipitation additions than reductions; this was especially evident in drier ecosystems. Additionally, overall relationships between the magnitude of productivity responses and the magnitude of precipitation change were saturating in form. The saturating form of this relationship was likely driven by ANPP responses to very extreme precipitation increases, although there were limited studies imposing extreme precipitation change, and there was considerable variation among experiments. Finally, this highlights the importance of incorporating gradients of manipulations, ranging from extreme drought to extreme precipitation increases into future climate change experiments. Additionally, policy and land management decisions related to global change scenarios should consider how ANPP and BNPP responses may differ, and that ecosystem responses to extreme events might not be predicted from relationships found under moderate environmental changes.« less

Structural elucidation of main ozonation products of the artificial sweeteners cyclamate and acesulfame.

PubMed

Scheurer, Marco; Godejohann, Markus; Wick, Arne; Happel, Oliver; Ternes, Thomas A; Brauch, Heinz-Jürgen; Ruck, Wolfgang K L; Lange, Frank Thomas

2012-05-01

The two artificial sweeteners cyclamate (CYC) and acesulfame (ACE) have been detected in wastewater and drinking water treatment plants. As in both facilities ozonation might be applied, it is important to find out if undesired oxidation products (OPs) are formed. For the separation and detection of the OPs, several analytical techniques, including nuclear magnetic resonance experiments, were applied. In order to distinguish between direct ozone reaction and a radical mechanism, experiments were carried out at different pH values with and without scavenging OH radicals. Kinetic experiments were used for confirmation that the OPs are formed during short ozone contact time applied in waterworks. Samples from a waterworks using bank filtrate as raw water were analyzed in order to prove that the identified OPs are formed in real and full-scale ozone applications. In the case of CYC, oxidation mainly occurs at the carbon atom, where the sulfonamide moiety is bound to the cyclohexyl ring. Consequently, amidosulfonic acid and cyclohexanone are formed as main OPs of CYC. When ozone reacts at another carbon atom of the ring a keto moiety is introduced into the CYC molecule. Acetic acid and the product ACE OP170, an anionic compound with m/z=170 and an aldehyde hydrate moiety, were identified as the main OPs for ACE. The observed reaction products suggest an ozone reaction according to the Criegee mechanism due to the presence of a C=C double bond. ACE OP170 was also detected after the ozonation unit of a full-scale drinking water treatment plant which uses surface water-influenced bank filtrate as raw water. Acesulfame can be expected to be found in anthropogenic-influenced raw water used for drinking water production. However, when ACE OP170 is formed during ozonation, it is not expected to cause any problem for drinking water suppliers, because the primary findings suggest its removal in subsequent treatment steps, such as activated carbon filters.

Asymmetric responses of primary productivity to precipitation extremes: A synthesis of grassland precipitation manipulation experiments.

PubMed

Wilcox, Kevin R; Shi, Zheng; Gherardi, Laureano A; Lemoine, Nathan P; Koerner, Sally E; Hoover, David L; Bork, Edward; Byrne, Kerry M; Cahill, James; Collins, Scott L; Evans, Sarah; Gilgen, Anna K; Holub, Petr; Jiang, Lifen; Knapp, Alan K; LeCain, Daniel; Liang, Junyi; Garcia-Palacios, Pablo; Peñuelas, Josep; Pockman, William T; Smith, Melinda D; Sun, Shanghua; White, Shannon R; Yahdjian, Laura; Zhu, Kai; Luo, Yiqi

2017-10-01

Climatic changes are altering Earth's hydrological cycle, resulting in altered precipitation amounts, increased interannual variability of precipitation, and more frequent extreme precipitation events. These trends will likely continue into the future, having substantial impacts on net primary productivity (NPP) and associated ecosystem services such as food production and carbon sequestration. Frequently, experimental manipulations of precipitation have linked altered precipitation regimes to changes in NPP. Yet, findings have been diverse and substantial uncertainty still surrounds generalities describing patterns of ecosystem sensitivity to altered precipitation. Additionally, we do not know whether previously observed correlations between NPP and precipitation remain accurate when precipitation changes become extreme. We synthesized results from 83 case studies of experimental precipitation manipulations in grasslands worldwide. We used meta-analytical techniques to search for generalities and asymmetries of aboveground NPP (ANPP) and belowground NPP (BNPP) responses to both the direction and magnitude of precipitation change. Sensitivity (i.e., productivity response standardized by the amount of precipitation change) of BNPP was similar under precipitation additions and reductions, but ANPP was more sensitive to precipitation additions than reductions; this was especially evident in drier ecosystems. Additionally, overall relationships between the magnitude of productivity responses and the magnitude of precipitation change were saturating in form. The saturating form of this relationship was likely driven by ANPP responses to very extreme precipitation increases, although there were limited studies imposing extreme precipitation change, and there was considerable variation among experiments. This highlights the importance of incorporating gradients of manipulations, ranging from extreme drought to extreme precipitation increases into future climate change experiments. Additionally, policy and land management decisions related to global change scenarios should consider how ANPP and BNPP responses may differ, and that ecosystem responses to extreme events might not be predicted from relationships found under moderate environmental changes. © 2017 John Wiley & Sons Ltd.

Boosting subsurface life: is subseafloor sediment a natural catalyst for radiolytic hydrogen production?

NASA Astrophysics Data System (ADS)

Sauvage, J.; Graham, D.; Spivack, A. J.; Dunlea, A. G.; Murray, R. W.; D'Hondt, S.

2014-12-01

Naturally occurring production of molecular hydrogen (H2) by water radiolysis may be a fundamentally important source of electron donors (energy) for life in subsurface environments where organic matter is scarce. Previous studies with very high gamma radiation rates and wet mineral phases have reported high H2 production relative to production from water radiolysis in the absence of solid phases. Numerical calculations by other previous studies have predicted enhanced H2 production from seawater radiolysis relative to pure water radiolysis, due to the interaction of anions with hydroxyl radicals. Given these reports, the potential catalytic influences of solid and dissolved chemical phases on radiolytic H2 production need to be carefully quantified in order to fully evaluate the role of radiolytic H2 as a microbial energy source. For such quantification, we undertook gamma-irradiation experiments with pure water, deep ocean water and mixtures (slurries, φ = 0.85) of seawater with: North Pacific abyssal clay and calcareous oozes, coastal sediment, zirconium dioxide, and zeolite. We carried out our experiments at the Rhode Island Nuclear Science Center using a 37Cesium source at low dose rates (up to 0.1 Gy/hr). Our results to date include the following. First, the per-dose radiolytic H2 yield of pure water at low dose rates is directly comparable to the per-dose yield at much higher dose rates (ca. 1 kGy/hr); this result indicates that H2 production rate is linearly related to radiation dose rate across four orders of magnitude. Second, there is no statistically significant difference (90% confidence limit) between the radiolytic H2 yield from pure water and that from seawater; this result rules out influence of abundant seawater salts on H2 yield from water radiolysis. Third, H2 production from a mixture of abyssal clay and seawater is 25% higher than the yield from pure water. This enhanced yield is consistent with catalysis of radiolytic H2 production by zeolite.

To Prescribe or Not to Prescribe? Consumer Access to Life-Enhancing Products

PubMed Central

Marinova, Detelina; Kozlenkova, Irina V; Cuttler, Leona; Silvers, J B

2017-01-01

Abstract With rapid biotechnological advances in specialty drugs and direct-to-consumer advertising, consumers are under tremendous pressure to look, perform, feel, and live better. This is often accomplished through the use of life-enhancing products, sometimes referred to as performance-enhancing products, which can be accessed only through a gatekeeper, such as a physician. Integrating consumer and medical research, this article investigates how physicians make trade-offs between objective medical and nonmedical factors to determine consumers’ access to life-enhancing products by examining US pediatric endocrinologists’ prescription decisions for growth hormone (GH) for healthy but short children. The results of a conjoint study indicate that consumer medical criteria have less impact on a physician’s decision to prescribe GH if the consumer requests a prescription or the physician believes in the intangible product benefits, and more impact when the product is more expensive. A physician’s length of experience increases the impact of consumer medical criteria and decreases the influence of a consumer’s preference for a prescription on the decision to prescribe. Overall, this research shows that not all consumers have equal access to life-enhancing products; their access depends on a complex combination of medical and nonmedical factors related to the consumer, product, and the physician. PMID:29928069

Performance Testing of Molten Regolith Electrolysis with Transfer of Molten Material for the Production of Oxygen and Metals on the Moon

NASA Technical Reports Server (NTRS)

Sibille, Laurent; Sadoway, Donald; Tripathy, Prabhat; Standish, Evan; Sirk, Aislinn; Melendez, Orlando; Stefanescu, Doru

2010-01-01

Previously, we have demonstrated the production of oxygen by electrolysis of molten regolith simulants at temperatures near 1600 C. Using an inert anode and suitable cathode, direct electrolysis (no supporting electrolyte) of the molten silicate is carried out, resulting in the production of molten metallic products at the cathode and oxygen gas at the anode. Initial direct measurements of current efficiency have confirmed that the process offer potential advantages of high oxygen production rates in a smaller footprint facility landed on the moon, with a minimum of consumables brought from Earth. We now report the results of a scale-up effort toward the goal of achieving production rates equivalent to 1 metric ton O2/year, a benchmark established for the support of a lunar base. We previously reported on the electrochemical behavior of the molten electrolyte as dependent on anode material, sweep rate and electrolyte composition in batches of 20-200g and at currents of less than 0.5 A. In this paper, we present the results of experiments performed at currents up to 10 Amperes) and in larger volumes of regolith simulant (500 g - 1 kg) for longer durations of electrolysis. The technical development of critical design components is described, including: inert anodes capable of passing continuous currents of several Amperes, container materials selection, direct gas analysis capability to determine the gas components co-evolving with oxygen. To allow a continuous process, a system has been designed and tested to enable the withdrawal of cathodically-reduced molten metals and spent molten oxide electrolyte. The performance of the withdrawal system is presented and critiqued. The design of the electrolytic cell and the configuration of the furnace were supported by modeling the thermal environment of the system in an effort to realize a balance between external heating and internal joule heating. We will discuss the impact these simulations and experimental findings have on the design of a suitable prototype for lunar applications

The Productive Ward: releasing Time to Care(™)--what we can learn from the literature for implementation.

PubMed

White, Mark; Wells, John Sg; Butterworth, Tony

2014-10-01

This paper reviews the Productive Ward: Releasing Time to Care™ literature, identifying and discussing the key characteristics that may contribute to successful implementation. It is 5 years since the official UK launch of the Productive Ward, and the Republic of Ireland commenced a phased, national implementation programme in 2011. Thus it is timely to reflect on the implementation lessons learned to date and described in the literature. Using taxonomic mapping, this paper evaluates the current state of the literature that pertains to Productive Ward implementation experience; success factors; reports, and assessments. Seven common contextual characteristics were identified: robust and engaging communication; enabling and empowering roles; appropriate training; project planning and management; leadership; corporate/management engagement and support; and financial and human resource commitment. The key characteristics identified have a direct impact on the implementation of the Productive Ward. The interplay between these key characteristics and how this interplay influences successful implementation of the Productive Ward warrants further research. Acknowledging and embracing the seven characteristics during implementation will positively improve the progress and success of the initiatives implementation. © 2013 John Wiley & Sons Ltd.

Optimization of the preparation conditions of ceramic products using drinking water treatment sludges.

PubMed

Zamora, R M Ramirez; Ayala, F Espesel; Garcia, L Chavez; Moreno, A Duran; Schouwenaars, R

2008-11-01

The aim of this work is to optimize, via Response Surface Methodology, the values of the main process parameters for the production of ceramic products using sludges obtained from drinking water treatment in order to valorise them. In the first experimental stage, sludges were collected from a drinking water treatment plant for characterization. In the second stage, trials were carried out to elaborate thin cross-section specimens and fired bricks following an orthogonal central composite design of experiments with three factors (sludge composition, grain size and firing temperature) and five levels. The optimization parameters (Y(1)=shrinking by firing (%), Y(2)=water absorption (%), Y(3)=density (g/cm(3)) and Y(4)=compressive strength (kg/cm(2))) were determined according to standardized analytical methods. Two distinct physicochemical processes were active during firing at different conditions in the experimental design, preventing the determination of a full response surface, which would allow direct optimization of production parameters. Nevertheless, the temperature range for the production of classical red brick was closely delimitated by the results; above this temperature, a lightweight ceramic with surprisingly high strength was produced, opening possibilities for the valorisation of a product with considerably higher added value than what was originally envisioned.

Plant diversity effects on grassland productivity are robust to both nutrient enrichment and drought

PubMed Central

Isbell, Forest; Manning, Pete; Connolly, John; Bruelheide, Helge; Ebeling, Anne; Roscher, Christiane; van Ruijven, Jasper; Weigelt, Alexandra; Wilsey, Brian; Beierkuhnlein, Carl; de Luca, Enrica; Griffin, John N.; Hautier, Yann; Hector, Andy; Jentsch, Anke; Kreyling, Jürgen; Lanta, Vojtech; Loreau, Michel; Meyer, Sebastian T.; Mori, Akira S.; Naeem, Shahid; Palmborg, Cecilia; Polley, H. Wayne; Reich, Peter B.; Schmid, Bernhard; Siebenkäs, Alrun; Seabloom, Eric; Thakur, Madhav P.; Tilman, David; Vogel, Anja; Eisenhauer, Nico

2016-01-01

Global change drivers are rapidly altering resource availability and biodiversity. While there is consensus that greater biodiversity increases the functioning of ecosystems, the extent to which biodiversity buffers ecosystem productivity in response to changes in resource availability remains unclear. We use data from 16 grassland experiments across North America and Europe that manipulated plant species richness and one of two essential resources—soil nutrients or water—to assess the direction and strength of the interaction between plant diversity and resource alteration on above-ground productivity and net biodiversity, complementarity, and selection effects. Despite strong increases in productivity with nutrient addition and decreases in productivity with drought, we found that resource alterations did not alter biodiversity–ecosystem functioning relationships. Our results suggest that these relationships are largely determined by increases in complementarity effects along plant species richness gradients. Although nutrient addition reduced complementarity effects at high diversity, this appears to be due to high biomass in monocultures under nutrient enrichment. Our results indicate that diversity and the complementarity of species are important regulators of grassland ecosystem productivity, regardless of changes in other drivers of ecosystem function. PMID:27114579

Using Model-Based Systems Engineering To Provide Artifacts for NASA Project Life-Cycle and Technical Reviews

NASA Technical Reports Server (NTRS)

Parrott, Edith L.; Weiland, Karen J.

2017-01-01

The ability of systems engineers to use model-based systems engineering (MBSE) to generate self-consistent, up-to-date systems engineering products for project life-cycle and technical reviews is an important aspect for the continued and accelerated acceptance of MBSE. Currently, many review products are generated using labor-intensive, error-prone approaches based on documents, spreadsheets, and chart sets; a promised benefit of MBSE is that users will experience reductions in inconsistencies and errors. This work examines features of SysML that can be used to generate systems engineering products. Model elements, relationships, tables, and diagrams are identified for a large number of the typical systems engineering artifacts. A SysML system model can contain and generate most systems engineering products to a significant extent and this paper provides a guide on how to use MBSE to generate products for project life-cycle and technical reviews. The use of MBSE can reduce the schedule impact usually experienced for review preparation, as in many cases the review products can be auto-generated directly from the system model. These approaches are useful to systems engineers, project managers, review board members, and other key project stakeholders.

Restorative dentistry productivity of senior students engaged in comprehensive care.

PubMed

Blalock, John S; Callan, Richard S; Lazarchik, David A; Frank Caughman, W; Looney, Stephen

2012-12-01

In dental education, various clinical delivery models are used to educate dental students. The quantitative and qualitative measures used to assess the outcomes of these models are varied. Georgia Health Sciences University College of Dental Medicine has adopted a version of a general dentistry comprehensive care dental education hybrid model. Outcome assessments were developed to evaluate the effectiveness of this delivery model. The aim of this study was to compare the number of restorative procedures performed by senior dental students under a discipline-based model versus senior student productivity engaged in comprehensive care as part of a hybrid model. The rate of senior students' productivity in performing various restorative procedures was tracked over four years, and a comparison was made. In the first two years, the seniors operated in a discipline-based model, while in the last two years the seniors operated in a comprehensive care hybrid model. The results showed that there was a significant increase in productivity by the students in terms of direct and indirect restorations. This increase in productivity may indicate that the comprehensive care model may be a more productive model, thereby enhancing clinical experiences for the students, improving operating efficiency for the schools, and ultimately increasing clinical income.

Experience and convergence in spiritual direction.

PubMed

Evans, Jean

2015-02-01

The practice of spiritual direction concerns the human experience of God. As praxis, spiritual direction has a long tradition in Western Christianity. It is a process rooted in spirituality with theology as its foundation. This paper explores the convergences between aspects of philosophy (contemplative awareness), psychology (Rogerian client-centered approach) and phenomenology. There are significant points of convergence between phenomenology and spiritual direction: first, in Ignatius of Loyola's phenomenological approach to his religious experience; second, in the appropriation by spiritual directors of concepts of epochē and empathy; third, in the process of "unpacking" religious experience within a spiritual direction interview.

Transfer of movement sequences: bigger is better.

PubMed

Dean, Noah J; Kovacs, Attila J; Shea, Charles H

2008-02-01

Experiment 1 was conducted to determine if proportional transfer from "small to large" scale movements is as effective as transferring from "large to small." We hypothesize that the learning of larger scale movement will require the participant to learn to manage the generation, storage, and dissipation of forces better than when practicing smaller scale movements. Thus, we predict an advantage for transfer of larger scale movements to smaller scale movements relative to transfer from smaller to larger scale movements. Experiment 2 was conducted to determine if adding a load to a smaller scale movement would enhance later transfer to a larger scale movement sequence. It was hypothesized that the added load would require the participants to consider the dynamics of the movement to a greater extent than without the load. The results replicated earlier findings of effective transfer from large to small movements, but consistent with our hypothesis, transfer was less effective from small to large (Experiment 1). However, when a load was added during acquisition transfer from small to large was enhanced even though the load was removed during the transfer test. These results are consistent with the notion that the transfer asymmetry noted in Experiment 1 was due to factors related to movement dynamics that were enhanced during practice of the larger scale movement sequence, but not during the practice of the smaller scale movement sequence. The findings that the movement structure is unaffected by transfer direction but the movement dynamics are influenced by transfer direction is consistent with hierarchal models of sequence production.

Conflict: an imperative for success.

PubMed

Wenzel, F J

1986-04-01

Conflict in organizations of any type is inevitable. Medical institutions, particularly multispecialty clinics, are no exception. This paper presents an examination of the anatomy of conflict in group practice settings. Several case studies, including the "Hunterdon Experiment," are presented to illustrate the outcome of conflict situations where management was unable to direct its energy to productive ends. Recommendations are made for identifying, considering, and resolving conflicts in a proactive fashion. The conflict management role of the top management of the organization is described, with particular emphasis on the pivotal position of the Medical Director.

Heavy flavor at the Tevatron

NASA Astrophysics Data System (ADS)

Leo, S.

2016-07-01

The CDF and D0 experiments at the Tevatron proton-antiproton collider have pioneered and established the role of hadron collisions in exploring flavor physics through a broad program that continues to offer competitive results. I report on latest results in the flavor sector obtained using the whole CDF and D0 data sets corresponding to {˜}10{ fb-1} of integrated luminosity; including B-mesons spectroscopy and production asymmetries, flavor specific decay bottom-strange mesons lifetime. I also present measurements of direct and indirect CP violation in bottom and charm meson decays.

Purification and cultivation of human pituitary growth hormone secreting cells

NASA Technical Reports Server (NTRS)

Hymer, W. C.

1979-01-01

Efforts were directed towards maintenance of actively secreting human pituitary growth hormone cells (somatotrophs) in vitro. The production of human growth hormone (hGH) by this means would be of benefit for the treatment of certain human hypopituitary diseases such as dwarfism. One of the primary approaches was the testing of agents which may logically be expected to increase hGH release. The progress towards this goal is summarized. Results from preliminary experiments dealing with electrophoresis of pituitary cell for the purpose of somatotroph separation are described.

Identifiable piezoelectric security system design

NASA Astrophysics Data System (ADS)

Li, Zhenyu; Zhang, Xiaoming

2017-10-01

Directing at the disadvantages of low environmental suitability, inferior anti-interference ability and being easy to be found and destroyed in existing security product, a kind of identifiable piezoelectric security system based on piezoelectric cable is designed. The present system gathers vibration signals of different moving bodies, such as human, vehicles, animals and so on, with piezoelectric cable buried under -ground and distinguishes the different moving bodies through recognition algorithm and thus giving an alarm. As is shown in experiments, the present system has the features of good concealment and high accuracy in distinguishing moving bodies.

Searching for new physics with three-particle correlations in pp collisions at the LHC

NASA Astrophysics Data System (ADS)

Sanchis-Lozano, Miguel-Angel; Sarkisyan-Grinbaum, Edward K.

2018-06-01

New phenomena involving pseudorapidity and azimuthal correlations among final-state particles in pp collisions at the LHC can hint at the existence of hidden sectors beyond the Standard Model. In this paper we rely on a correlated-cluster picture of multiparticle production, which was shown to account for the ridge effect, to assess the effect of a hidden sector on three-particle correlations concluding that there is a potential signature of new physics that can be directly tested by experiments using well-known techniques.

Measurements of top quark properties at CDF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kraan, Aafke C.; /Pennsylvania U.

The top quark with its mass of about 172 GeV/c{sup 2} is the most massive fundamental particle observed by experiment. In this talk they highlight the most recent measurements of several top quark properties performed with the CDF detector based on data samples corresponding to integrated luminosities up to 1 fb{sup -1}. These results include a search for top quark pair production via new massive resonances, measurements of the helicity of the W boson from top-quark decay, and a direct limit on the lifetime of the top quark.

Needleless Electrospinning of Pure and Blended Chitosan

NASA Astrophysics Data System (ADS)

Grimmelsmann, Nils; Homburg, Sarah Vanessa; Ehrmann, Andrea

2017-08-01

Chitosan is a biopolymer with bactericidal, fungicidal, hemostatic and other interesting properties. It can be used, e.g., in medical products, as a filter medium, in biotechnological purposes etc. For these possible applications, nanofiber mats with a large inner surface will be most efficient. This is why in a recent project, the electrospinning properties of pure chitosan as well as chitosan blended with poly(ethylene oxide) were investigated. Using a needleless nanospinning process, the technology under examination can be upscaled from lab to industrial scale, enabling direct transfer of the gained experiences to the intended application.

The Impact of Inventory Management on Stock-Outs of Essential Drugs in Sub-Saharan Africa: Secondary Analysis of a Field Experiment in Zambia.

PubMed

Leung, Ngai-Hang Z; Chen, Ana; Yadav, Prashant; Gallien, Jérémie

2016-01-01

To characterize the impact of widespread inventory management policies on stock-outs of essential drugs in Zambia's health clinics and develop related recommendations. Daily clinic storeroom stock levels of artemether-lumefantrine (AL) products in 2009-2010 were captured in 145 facilities through photography and manual transcription of paper forms, then used to determine historical stock-out levels and estimate demand patterns. Delivery lead-times and estimates of monthly facility accessibility were obtained through worker surveys. A simulation model was constructed and validated for predictive accuracy against historical stock-outs, then used to evaluate various changes potentially affecting product availability. While almost no stock-outs of AL products were observed during Q4 2009 consistent with primary analysis, up to 30% of surveyed facilities stocked out of some AL product during Q1 2010 despite ample inventory being simultaneously available at the national warehouse. Simulation experiments closely reproduced these results and linked them to the use of average past monthly issues and failure to capture lead-time variability in current inventory control policies. Several inventory policy enhancements currently recommended by USAID | DELIVER were found to have limited impact on product availability. Inventory control policies widely recommended and used for distributing medicines in sub-Saharan Africa directly account for a substantial fraction of stock-outs observed in common situations involving demand seasonality and facility access interruptions. Developing central capabilities in peripheral demand forecasting and inventory control is critical. More rigorous independent peer-reviewed research on pharmaceutical supply chain management in low-income countries is needed.

Estimating a Service-Life Distribution Based on Production Counts and a Failure Database

DOE PAGES

Ryan, Kenneth J.; Hamada, Michael Scott; Vardeman, Stephen B.

2017-04-01

A manufacturer wanted to compare the service-life distributions of two similar products. These concern product lifetimes after installation (not manufacture). For each product, there were available production counts and an imperfect database providing information on failing units. In the real case, these units were expensive repairable units warrantied against repairs. Failure (of interest here) was relatively rare and driven by a different mode/mechanism than ordinary repair events (not of interest here). Approach: Data models for the service life based on a standard parametric lifetime distribution and a related limited failure population were developed. These models were used to develop expressionsmore » for the likelihood of the available data that properly accounts for information missing in the failure database. Results: A Bayesian approach was employed to obtain estimates of model parameters (with associated uncertainty) in order to investigate characteristics of the service-life distribution. Custom software was developed and is included as Supplemental Material to this case study. One part of a responsible approach to the original case was a simulation experiment used to validate the correctness of the software and the behavior of the statistical methodology before using its results in the application, and an example of such an experiment is included here. Because of confidentiality issues that prevent use of the original data, simulated data with characteristics like the manufacturer’s proprietary data are used to illustrate some aspects of our real analyses. Lastly, we also note that, although this case focuses on rare and complete product failure, the statistical methodology provided is directly applicable to more standard warranty data problems involving typically much larger warranty databases where entries are warranty claims (often for repairs) rather than reports of complete failures.« less

Estimating a Service-Life Distribution Based on Production Counts and a Failure Database

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryan, Kenneth J.; Hamada, Michael Scott; Vardeman, Stephen B.

A manufacturer wanted to compare the service-life distributions of two similar products. These concern product lifetimes after installation (not manufacture). For each product, there were available production counts and an imperfect database providing information on failing units. In the real case, these units were expensive repairable units warrantied against repairs. Failure (of interest here) was relatively rare and driven by a different mode/mechanism than ordinary repair events (not of interest here). Approach: Data models for the service life based on a standard parametric lifetime distribution and a related limited failure population were developed. These models were used to develop expressionsmore » for the likelihood of the available data that properly accounts for information missing in the failure database. Results: A Bayesian approach was employed to obtain estimates of model parameters (with associated uncertainty) in order to investigate characteristics of the service-life distribution. Custom software was developed and is included as Supplemental Material to this case study. One part of a responsible approach to the original case was a simulation experiment used to validate the correctness of the software and the behavior of the statistical methodology before using its results in the application, and an example of such an experiment is included here. Because of confidentiality issues that prevent use of the original data, simulated data with characteristics like the manufacturer’s proprietary data are used to illustrate some aspects of our real analyses. Lastly, we also note that, although this case focuses on rare and complete product failure, the statistical methodology provided is directly applicable to more standard warranty data problems involving typically much larger warranty databases where entries are warranty claims (often for repairs) rather than reports of complete failures.« less