NASA Astrophysics Data System (ADS)
Liu, Xinjie; Liu, Liangyun
2017-04-01
The Fraunhofer Line Discrimination (FLD) principle is the main approach used for the retrieval of solar-induced chlorophyll fluorescence (SIF). The basic assumption of the FLD principle is that the apparent reflectance spectra without SIF in-filling are smooth in the region of the absorption bands. However, in fact, this assumption is not valid due to the so-called "direct radiation in-filling" effect caused by the non-linear contribution of direct and diffuse radiation at the oxygen absorption bands, which are widely used for ground-based SIF retrieval. In this study, we first analyzed the physical mechanism of the direct radiation in-filling effect on the oxygen absorption bands and found that the bias in the SIF retrieval caused by the direct radiation in-filling effect at the O2-A band was less than 20% based on the use of a simulated dataset. Secondly, we established a simple correction model of the direct radiation in-filling effect. We found that the direct radiation in-filling effect at the O2-A band was directly proportional to the difference between the reflectance of the direct and diffuse radiation, and that the coefficient of proportionality was well correlated with the diffuse-to-global radiation ratio in the form of a quadratic function. The coefficient of determination (R-squared) for this correlation was 0.97. Finally, the model was validated using both simulated and field datasets. The validation results show that the bias in the SIF retrieval caused by the direct radiation in-filling effect can be efficiently corrected using the model proposed in this paper. This study thus provides a possible approach to estimating and correcting for the direct radiation-infilling effect using prior knowledge of the BRDF characteristics of direct and diffuse radiation for specific targets.
The effects of solar radiation and black body re-radiation on thermal comfort.
Hodder, Simon; Parsons, Ken
2008-04-01
When the sun shines on people in enclosed spaces, such as in buildings or vehicles, it directly affects thermal comfort. There is also an indirect effect as surrounding surfaces are heated exposing a person to re-radiation. This laboratory study investigated the effects of long wave re-radiation on thermal comfort, individually and when combined with direct solar radiation. Nine male participants (26.0 +/- 4.7 years) took part in three experimental sessions where they were exposed to radiation from a hot black panel heated to 100 degrees C; direct simulated solar radiation of 600 Wm(-2) and the combined simulated solar radiation and black panel radiation. Exposures were for 30 min, during which subjective responses and mean skin temperatures were recorded. The results showed that, at a surface temperature of 100 degrees C (close to maximum in practice), radiation from the flat black panel provided thermal discomfort but that this was relatively small when compared with the effects of direct solar radiation. It was concluded that re-radiation, from a dashboard in a vehicle, for example, will not have a major direct influence on thermal comfort and that existing models of thermal comfort do not require a specific modification. These results showed that, for the conditions investigated, the addition of re-radiation from internal components has an effect on thermal sensation when combined with direct solar radiation. However, it is not considered that it will be a major factor in a real world situation. This is because, in practice, dashboards are unlikely to maintain very high surface temperatures in vehicles without an unacceptably high air temperature. This study quantifies the contribution of short- and long-wave radiation to thermal comfort. The results will aid vehicle designers to have a better understanding of the complex radiation environment. These include direct radiation from the sun as well as re-radiation from the dashboard and other internal surfaces.
NASA Technical Reports Server (NTRS)
Su, Jing; Huang, Jianping; Fu, Qiang; Minnis, Patrick; Ge, Jinming; Bi, Jianrong
2008-01-01
The impact of Asian dust on cloud radiative forcing during 2003-2006 is studied by using the Earth's Radiant Energy Budget Scanner (CERES) data and the Fu-Liou radiative transfer model. Analysis of satellite data shows that the dust aerosol significantly reduced the cloud cooling effect at TOA. In dust contaminated cloudy regions, the 4-year mean values of the instantaneous shortwave, longwave and net cloud radiative forcing are -138.9, 69.1, and -69.7 Wm(sup -2), which are 57.0, 74.2, and 46.3%, respectively, of the corresponding values in more pristine cloudy regions. The satellite-retrieved cloud properties are significantly different in the dusty regions and can influence the radiative forcing indirectly. The contributions to the cloud radiation forcing by the dust direct, indirect and semi-direct effects are estimated using combined satellite observations and Fu-Liou model simulation. The 4-year mean value of combination of indirect and semi-direct shortwave radiative forcing (SWRF) is 82.2 Wm(sup -2), which is 78.4% of the total dust effect. The direct effect is only 22.7 Wm(sup -2), which is 21.6% of the total effect. Because both first and second indirect effects enhance cloud cooling, the aerosol-induced cloud warming is mainly the result of the semi-direct effect of dust.
Radioresistance of GGG Sequences to Prompt Strand Break Formation from Direct-Type Radiation Damage
Black, Paul J.; Miller, Adam S.; Hayes, Jeffrey J.
2016-01-01
Purpose As humans, we are constantly exposed to ionizing radiation from natural, man-made and cosmic sources which can damage DNA, leading to deleterious effects including cancer incidence. In this work we introduce a method to monitor strand breaks resulting from damage due to the direct effect of ionizing radiation and provide evidence for sequence-dependent effects leading to strand breaks. Materials and methods To analyze only DNA strand breaks caused by radiation damage due to the direct effect of ionizing radiation, we combined an established technique to generate dehydrated DNA samples with a technique to analyze single strand breaks on short oligonucleotide sequences via denaturing gel electrophoresis. Results We find that direct damage primarily results in a reduced number of strand breaks in guanine triplet regions (GGG) when compared to isolated guanine (G) bases with identical flanking base context. In addition, we observe strand break behavior possibly indicative of protection of guanine bases when flanked by pyrimidines, and sensitization of guanine to strand break when flanked by adenine (A) bases in both isolated G and GGG cases. Conclusions These observations provide insight into the strand break behavior in GGG regions damaged via the direct effect of ionizing radiation. In addition, this could be indicative of DNA sequences that are naturally more susceptible to strand break due to the direct effect of ionizing radiation. PMID:27349757
Two years comparative studies on biological effects of environmental UV radiation
NASA Astrophysics Data System (ADS)
Grof, P.; Ronto, Gyorgyi; Gaspar, S.; Berces, A.; Szabo, Laszlo D.
1994-07-01
A method has been developed for determination of the biologically effective UV dose based on T7 phage as biosensor. In field experiments clockwork driven telescope has been used for determining doses from direct and global (direct plus diffuse) solar radiation. On fine summer days at mid-latitude this arrangement allowed the following comparisons: measured doses from direct and global radiation obtained at the same time and measuring site reflecting the biological importance of diffuse radiation; direct and global radiation obtained at the same time and measuring site reflecting the biological importance of diffuse radiation; direct and global doses obtained at the same time on different measuring sites (downtown, suburb, outside the town) reflecting the differences caused by air quality; direct and global doses obtained on the same measuring place, in summertime of two different years reflecting the importance of the long-term measurements for estimating the biological risk caused by increased UV-B radiation; measured data and model calculations.
NASA Astrophysics Data System (ADS)
Hampson, R. E.
Solar and cosmic radiation pose a number of physiological challenges to human spaceflight outside the protective region of Earth's magnetosphere. Aside from well-described effects of radiation on the blood-forming tissues of the hematopoietic system, there is increasing evidence of direct effects of radiation on the brain as evidenced by studies showing longitudinal decline in memory and cognitive function following radiation specifically directed at brain tissue. These indications strengthen the need to more fully research effects of radiation - particular those components associated with solar wind and galactic cosmic radiation - on the nervous system of mammals from rodents to humans.
A Study of Aerosol Direct Radiative Effect and Its Impacts on Global Terrestrial Ecosystem Cycles
NASA Astrophysics Data System (ADS)
Zhang, J.; Shao, S.; Zhou, L.
2017-12-01
Aerosols can absorb and scatter solar radiation, thus cause the total solar radiation reaching the surface to drop and the fraction of diffuse radiation to increase, which influence the surface radiation budget. The global surface radiation with and without consideration of aerosols are calculated by the Fu-Liou atmospheric radiative transfer model based on the MODIS aerosol products, CERES cloud products and other remote sensing data. The aerosol direct radiative effect is calculated based on the two scenarios of aerosols. Our calculation showed that in 2007, aerosols decreased the global total radiation by 9.16 W m-2 on average. Large decrease generally occurred in places with high AOD. As for the diffuse radiation, aerosol-induced changes were either positive or negative. Large increase generally occurred in places with high surface albedo, while large decrease generally occurred in places with high cloud fraction. The global aerosol-induced diffuse radiation change averaged 8.17 W m-2 in 2007. The aerosol direct radiative effect causes the photosynthetic active radiation to increase, and its influences on the global carbon cycle of terrestrial ecosystem are studied by using the Community Land Model (CLM). Calculations show that the aerosol direct radiative effects caused the global averages of terrestrial gross primary productivity (GPP), net primary productivity (NPP), heterotrophic respiration (RH), autotrophic respiration (RA), and net ecosystem productivity (Reco) to increase in 2007, with significant spatial variations however. The global average changes of GPP, NPP, NEP, RA, RH and Reco in 2007 were +6.47 gC m-2, +2.23 gC m-2, +0.34 gC m-2, +4.24 gC m-2, +1.89 gC m-2, +6.13 gC m-2, respectively. Examinations of the carbon fluxes show that the aerosol direct radiative effects influence the terrestrial ecosystem carbon cycles via the following two approaches: First, the diffuse fertilization effect, i.e. more diffuse radiation absorbed by vegetation shade leaves (photosynthetic active radiation, PAR) results in higher photosynthetic rates; Second, the radiation changes lead to changes in temperature and humidity, thereby changing the rates of the plant biophysical and chemical processes.
Indirect effects of radiation induce apoptosis and neuroinflammation in neuronal SH-SY5Y cells.
Saeed, Yasmeen; Xie, Bingjie; Xu, Jin; Wang, Hailong; Hassan, Murtaza; Wang, Rui; Hong, Ma; Hong, Qing; Deng, Yulin
2014-12-01
Recent studies have evaluated the role of direct radiation exposure in neurodegenerative disorders; however, association among indirect effects of radiation and neurodegenerative diseases remains rarely discussed. The objective of this study was to estimate the relative risk of neurodegeneration due to direct and indirect effects of radiation. (60)Co gamma ray was used as source of direct radiation whereas irradiated cell conditioned medium (ICCM) was used to mimic the indirect effect of radiation. To determine the potency of ICCM to inhibit neuronal cells survival colony forming assay was performed. The role of ICCM to induce apoptosis in neuronal SH-SY5Y cells was estimated by TUNEL assay and Annexin V/PI assay. Level of oxidative stress and the concentration of inflammatory cytokines after exposing to direct radiation and ICCM were evaluated by ELISA method. Expression of key apoptotic protein following direct and indirect radiation exposure was investigated by western blot technique. Experimental data manifest that ICCM account loss of cell survival and increase apoptotic induction in neuronal SH-SY5Y cells that was dependent on time and dose. Moreover, ICCM stimulate significant release of inflammatory cytokines i.e., tumor necrosis factor TNF-alpha (P < 0.01), Interleukin-1 (IL-1, P < 0.001), and Interleukin-6 (IL-6, P < 0.001) in neuronal SH-SY5Y cells and elevate the level of oxidative stress (MDA, P < 0.01). Up-regulation of key apoptotic protein expression i.e., Bax, Bid, cytochrome C, caspase-8 and caspase-3 confirms the toxicity of ICCM to neuronal cells. This study provides the evidence that indirect effect of radiation can be as much damaging to neuronal cells as direct radiation exposure can be. Hence, more focused research on estimation risks of indirect effect of radiation to CNS at molecular level may help to reduce the uncertainty about cure and cause of several neurodegenerative disorders.
Epigenetic Analysis of Heavy-ion Radiation Induced Bystander Effects in Mice
NASA Astrophysics Data System (ADS)
Zhang, Meng; Sun, Yeqing; Cui, Changna; Xue, Bei
Abstract: Radiation-induced bystander effect was defined as the induction of damage in neighboring non-hit cells by signals released from directly-irradiated cells. Recently, low dose of high LET radiation induced bystander effects in vivo have been reported more and more. It has been indicated that radiation induced bystander effect was localized not only in bystander tissues but also in distant organs. Genomic, epigenetic and proteomics plays significant roles in regulating heavy-ion radiation stress responses in mice. To identify the molecular mechanism that underlies bystander effects of heavy-ion radiation, the male Balb/c and C57BL mice were exposed head-only to 40, 200, 2000mGy dose of (12) C heavy-ion radiation, while the rest of the animal body was shielded. Directly radiation organ ear and the distant organ liver were detected on 1h, 6h, 12h and 24h after radiation, respectively. Methylation-sensitive amplification polymorphism (MSAP) was used to monitor the level of polymorphic genomic DNA methylation changed with dose and time effects. The results show that heavy-ion irradiated mouse head could induce genomic DNA methylation changes significantly in both the directly radiation organ ear and the distant organ liver. The percent of DNA methylation changes were time-dependent and tissue-specific. Demethylation polymorphism rate was highest separately at 1 h in 200 mGy and 6 h in 2000 mGy after irradiation. The global DNA methylation changes tended to occur in the CG sites. The results illustrated that genomic methylation changes of heavy ion radiation-induced bystander effect in liver could be obvious 1 h after radiation and achieved the maximum at 6 h, while the changes could recover gradually at 12 h. The results suggest that mice head exposed to heavy-ion radiation can induce damage and methylation pattern changed in both directly radiation organ ear and distant organ liver. Moreover, our findings are important to understand the molecular mechanism of radiation induced bystander effects in vivo.
While aerosol radiative effects have been recognized as some of the largest sources of uncertainty among the forcers of climate change, the verification of the spatial and temporal variability of the magnitude and directionality of aerosol radiative forcing has remained challengi...
The effects of solar radiation on thermal comfort.
Hodder, Simon G; Parsons, Ken
2007-01-01
The aim of this study was to investigate the relationship between simulated solar radiation and thermal comfort. Three studies investigated the effects of (1) the intensity of direct simulated solar radiation, (2) spectral content of simulated solar radiation and (3) glazing type on human thermal sensation responses. Eight male subjects were exposed in each of the three studies. In Study 1, subjects were exposed to four levels of simulated solar radiation: 0, 200, 400 and 600 Wm(-2). In Study 2, subjects were exposed to simulated solar radiation with four different spectral contents, each with a total intensity of 400 Wm(-2) on the subject. In Study 3, subjects were exposed through glass to radiation caused by 1,000 Wm(-2) of simulated solar radiation on the exterior surface of four different glazing types. The environment was otherwise thermally neutral where there was no direct radiation, predicted mean vote (PMV)=0+/-0.5, [International Standards Organisation (ISO) standard 7730]. Ratings of thermal sensation, comfort, stickiness and preference and measures of mean skin temperature (t(sk)) were taken. Increase in the total intensity of simulated solar radiation rather than the specific wavelength of the radiation is the critical factor affecting thermal comfort. Thermal sensation votes showed that there was a sensation scale increase of 1 scale unit for each increase of direct radiation of around 200 Wm(-2). The specific spectral content of the radiation has no direct effect on thermal sensation. The results contribute to models for determining the effects of solar radiation on thermal comfort in vehicles, buildings and outdoors.
The Impact of Aerosol Microphysical Representation in Models on the Direct Radiative Effect
NASA Astrophysics Data System (ADS)
Ridley, D. A.; Heald, C. L.
2017-12-01
Aerosol impacts the radiative balance of the atmosphere both directly and indirectly. There is considerable uncertainty remaining in the aerosol direct radiative effect (DRE), hampering understanding of the present magnitude of anthropogenic aerosol forcing and how future changes in aerosol loading will influence climate. Computationally expensive explicit aerosol microphysics are usually reserved for modelling of the aerosol indirect radiative effects that depend upon aerosol particle number. However, the direct radiative effects of aerosol are also strongly dependent upon the aerosol size distribution, especially particles between 0.2µm - 2µm diameter. In this work, we use a consistent model framework and consistent emissions to explore the impact of prescribed size distributions (bulk scheme) relative to explicit microphysics (sectional scheme) on the aerosol radiative properties. We consider the difference in aerosol burden, water uptake, and extinction efficiency resulting from the two representations, highlighting when and where the bulk and sectional schemes diverge significantly in their estimates of the DRE. Finally, we evaluate the modelled size distributions using in-situ measurements over a range of regimes to provide constraints on both the accumulation and coarse aerosol sizes.
Aerosol Direct Radiative Effects and Heating in the New Era of Active Satellite Observations
NASA Astrophysics Data System (ADS)
Matus, Alexander V.
Atmospheric aerosols impact the global energy budget by scattering and absorbing solar radiation. Despite their impacts, aerosols remain a significant source of uncertainty in our ability to predict future climate. Multi-sensor observations from the A-Train satellite constellation provide valuable observational constraints necessary to reduce uncertainties in model simulations of aerosol direct effects. This study will discuss recent efforts to quantify aerosol direct effects globally and regionally using CloudSat's radiative fluxes and heating rates product. Improving upon previous techniques, this approach leverages the capability of CloudSat and CALIPSO to retrieve vertically resolved estimates of cloud and aerosol properties critical for accurately evaluating the radiative impacts of aerosols. We estimate the global annual mean aerosol direct effect to be -1.9 +/- 0.6 W/m2, which is in better agreement with previously published estimates from global models than previous satellite-based estimates. Detailed comparisons against a fully coupled simulation of the Community Earth System Model, however, reveal that this agreement on the global annual mean masks large regional discrepancies between modeled and observed estimates of aerosol direct effects related to model biases in cloud cover. A low bias in stratocumulus cloud cover over the southeastern Pacific Ocean, for example, leads to an overestimate of the radiative effects of marine aerosols. Stratocumulus clouds over the southeastern Atlantic Ocean can enhance aerosol absorption by 50% allowing aerosol layers to remain self-lofted in an area of subsidence. Aerosol heating is found to peak at 0.6 +/- 0.3 K/day an altitude of 4 km in September when biomass burning reaches a maximum. Finally, the contributions of observed aerosols components are evaluated to estimate the direct radiative forcing of anthropogenic aerosols. Aerosol forcing is computed using satellite-based radiative kernels that describe the sensitivity of shortwave fluxes in response to aerosol optical depth. The direct radiative forcing is estimated to be -0.21 W/m2 with the largest contributions from pollution that is partially offset by a positive forcing from smoke aerosols. The results from these analyses provide new benchmarks on the global radiative effects of aerosols and offer new insights for improving future assessments.
Chapter 1: Direct Normal Radiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Myer, Daryl R.
2016-04-15
This chapter addresses the quantitative and qualitative aspects of the solar resource, the direct solar radiation. It discusses the total or integrated broadband direct beam extraterrestrial radiation (ETR). This total integrated irradiance is comprised of photons of electromagnetic radiation. The chapter also discusses the impact of the atmosphere and its effect upon the direct normal irradiance (DNI) beam radiation. The gases and particulates present in the atmosphere traversed by the direct beam reflect, absorb, and scatter differing spectral regions and proportions of the direct beam, and act as a variable filter. Knowledge of the available broadband DNI beam radiation resourcemore » data is essential in designing a concentrating photovoltaic (CPV) system. Spectral variations in the DNI beam radiation affect the performance of a CPV system depending on the solar cell technology used. The chapter describes propagation and scattering processes of circumsolar radiation (CSR), which includes the Mie scattering from large particles.« less
NASA Astrophysics Data System (ADS)
Tan, Chuting; Bashian, Nicholas H.; Hemmelgarn, Chase W.; Thio, Wesley J.; Lyons, Daniel J.; Zheng, Yuan F.; Cao, Lei R.; Co, Anne C.
2017-07-01
Radiation effects induced by gamma rays on battery performance were investigated by measuring the capacity and resistance of a series of battery coin cells in-situ directly under gamma radiation and ex-situ. An experimental setup was developed to charge and discharge batteries directly under gamma radiation, equipped with precise temperature control, at The Ohio State University Nuclear Reactor Lab. Latent effects induced by gamma radiation on battery components directly influence their performance. Charge and discharge capacity and overall resistance throughout a time span of several weeks post irradiation were monitored and compared to control groups. It was found that exposure to gamma radiation does not significantly alter the available capacity and the overall cell resistance immediately, however, battery performance significantly decreases with time post irradiation. Also, batteries exposed to a higher cumulative dose showed close-to-zero capacity at two-week post irradiation.
NASA Astrophysics Data System (ADS)
Rahmati, Ehsan; Ahmadi-Boroujeni, Mehdi
2018-04-01
One of the shortcomings of photoconductive (PC) antennas in terahertz (THz) generation is low effective radiated power in the desirable direction. In this paper, we propose a defective photonic crystal (DPC) substrate consisting of a customized 2D array of air holes drilled into a solid substrate in order to improve the radiation characteristics of THz PC antennas. The effect of the proposed structure on the performance of a conventional THz PC antenna has been examined from several aspects including radiation efficiency, directivity, and field distribution. By comparing the radiation performance of the THz antenna on the proposed DPC substrate to that of the conventional solid substrate, it is shown that the proposed technique can significantly improve the efficiency and directivity of the THz PC antenna over a wide frequency range. It is achieved by reducing the amount of power coupled to the substrate surface waves and limiting the radiation in undesirable directions. In addition, it is found that the sensitivity of directivity to the substrate thickness is considerably decreased and the adverse Fabry-Perot effects of the thick substrate are reduced by the application of the proposed DPC substrate.
NASA Technical Reports Server (NTRS)
Shi, J. J.; Matsui, T.; Tao, W.-K.; Tan, Q.; Peters-Lidard, C.; Chin, M.; Pickering, K.; Guy, N.; Lang, S.; Kemp, E. M.
2014-01-01
Aerosols affect the Earth's radiation balance directly and cloud microphysical processes indirectly via the activation of cloud condensation and ice nuclei. These two effects have often been considered separately and independently, hence the need to assess their combined impact given the differing nature of their effects on convective clouds. To study both effects, an aerosol-microphysics-radiation coupling, including Goddard microphysics and radiation schemes, was implemented into the NASA Unified Weather Research and Forecasting model (NU-WRF). Fully coupled NU-WRF simulations were conducted for a mesoscale convective system (MCS) that passed through the Niamey, Niger area on 6-7 August 2006 during an African Monsoon Multidisciplinary Analysis (AMMA) special observing period. The results suggest that rainfall is reduced when aerosol indirect effects are included, regardless of the aerosol direct effect. Daily mean radiation heating profiles in the area traversed by the MCS showed the aerosol (mainly mineral dust) direct effect had the largest impact near cloud tops just above 200 hectopascals where short-wave heating increased by about 0.8 Kelvin per day; the weakest long-wave cooling was at around 250 hectopascals. It was also found that more condensation and ice nuclei as a result of higher aerosol/dust concentrations led to increased amounts of all cloud hydrometeors because of the microphysical indirect effect, and the radiation direct effect acts to reduce precipitating cloud particles (rain, snow and graupel) in the middle and lower cloud layers while increasing the non-precipitating particles (ice) in the cirrus anvil. However, when the aerosol direct effect was activated, regardless of the indirect effect, the onset of MCS precipitation was delayed about 2 hours, in conjunction with the delay in the activation of cloud condensation and ice nuclei. Overall, for this particular environment, model set-up and physics configuration, the effect of aerosol radiative heating due to mineral dust overwhelmed the effect of the aerosols on microphysics.
NASA Astrophysics Data System (ADS)
Zhang, Meng; Sun, Yeqing; Xue, Bei; Wang, Xinwen; Wang, Jiawen
2016-07-01
Heavy-ion radiation could lead to bystander effect in neighboring non-hit cells by signals released from directly-irradiated cells. The exact mechanisms of radiation-induced bystander effect in distant organ remain obscure, yet accumulating evidence points to the role of DNA methylation changes in bystander effect. To identify the molecular mechanism that underlies bystander effects of heavy-ion radiation, the male Balb/c and C57BL mice were cranial exposed to 40, 200, 2000mGy dose of carbon heavy-ion radiation, while the rest of the animal body was shielded. The γH2AX foci as the DNA damage biomarker in directly irradiation organ ear and the distant organ liver were detected on 0, 1, 2, 6, 12 and 24h after radiation, respectively. Methylation-sensitive amplifcation polymorphism (MSAP) was used to monitor the level of polymorphic genomic DNA methylation changed with dose and time effects. The results show that cranial irradiated mice could induce the γH2AX foci and genomic DNA methylation changes significantly in both the directly irradiation organ ear and the distant organ liver. The percent of DNA methylation changes were time-dependent and tissue-specific. Demethylation polymorphism rate were highest separately at 1 h in 200 mGy and 6 h in 2000 mGy after irradiation in ear. The global DNA methylation changes tended to occur in the CG sites. We also found that the numbers of γH2AX foci and the genomic methylation changes of heavy-ion radiation-induced bystander effect in liver could be obvious 1 h after radiation and achieved the maximum at 6 h, while the changes could recover gradually at 12 h. The results suggest that mice head exposed to heavy-ion radiation can induce damage and methylation pattern changed in both directly radiation organ ear and distant organ liver. Moreover, our findings are important to understand the molecular mechanism of radiation induced bystander effects in vivo. Keywords: Heavy-ion radiation; Bystander effect; DNA methylation; γH2AX; Mice.
Response of different regional online coupled models to aerosol-radiation interactions
NASA Astrophysics Data System (ADS)
Forkel, Renate; Balzarini, Alessandra; Brunner, Dominik; Baró, Rocio; Curci, Gabriele; Hirtl, Marcus; Honzak, Luka; Jiménez-Guerrero, Pedro; Jorba, Oriol; Pérez, Juan L.; Pirovano, Guido; San José, Roberto; Schröder, Wolfram; Tuccella, Paolo; Werhahn, Johannes; Wolke, Ralf; Žabkar, Rahela
2016-04-01
The importance of aerosol-meteorology interactions and their representation in online coupled regional atmospheric chemistry-meteorology models was investigated in COST Action ES1004 (EuMetChem, http://eumetchem.info/). Case study results from different models (COSMO-Muscat, COSMO-ART, and different configurations of WRF-Chem), which were applied for Europe as a coordinated exercise for the year 2010, are analyzed with respect to inter-model variability and the response of the different models to direct and indirect aerosol-radiation interactions. The main focus was on two episodes - the Russian heat wave and wildfires episode in July/August 2010 and a period in October 2010 with enhanced cloud cover and rain and including an of Saharan dust transport to Europe. Looking at physical plausibility the decrease in downward solar radiation and daytime temperature due to the direct aerosol effect is robust for all model configurations. The same holds for the pronounced decrease in cloud water content and increase in solar radiation for cloudy conditions and very low aerosol concentrations that was found for WRF-Chem when aerosol cloud interactions were considered. However, when the differences were tested for statistical significance no significant differences in mean solar radiation and mean temperature between the baseline case and the simulations including the direct and indirect effect from simulated aerosol concentrations were found over Europe for the October episode. Also for the fire episode differences between mean temperature and radiation from the simulations with and without the direct aerosol effect were not significant for the major part of the modelling domain. Only for the region with high fire emissions in Russia, the differences in mean solar radiation and temperature due to the direct effect were found to be significant during the second half of the fire episode - however only for a significance level of 0.1. The few observational data indicate that the inclusion of aerosol radiative effects improves simulated temperatures in this area. In summary, the direct aerosol effect leads to lower temperatures and PBL heights for all seasons whereas the impact of the aerosol indirect effect on temperature and pollutant concentrations over Northern Europe was found to depend strongly on the season. It cannot be generalized whether the inclusion of aerosol radiative effects and aerosol cloud interactions based on simulated aerosol concentrations does improve the simulation results. Furthermore, assumptions how aerosol optical properties are calculated, i.e. on the aerosol's mixing state have a strong effect on simulated aerosol optical depth and the aerosol effect on incoming solar radiation and temperature. The inter-model variation of the response of different online coupled models suggests that further work comparing the methodologies and parameterizations used to represent the direct and indirect aerosol effect in these models is still necessary.
NASA Technical Reports Server (NTRS)
Ferrare, Richard; Feingold, Graham; Ghan, Steven; Ogren, John; Schmid, Beat; Schwartz, Stephen E.; Sheridan, Pat
2006-01-01
Atmospheric aerosols influence climate by scattering and absorbing radiation in clear air (direct effects) and by serving as cloud condensation nuclei, modifying the microphysical properties of clouds, influencing radiation and precipitation development (indirect effects). Much of present uncertainty in forcing of climate change is due to uncertainty in the relations between aerosol microphysical and optical properties and their radiative influences (direct effects) and between microphysical properties and their ability to serve as cloud condensation nuclei at given supersaturations (indirect effects). This paper introduces a special section that reports on a field campaign conducted at the Department of Energy Atmospheric Radiation Measurement site in North Central Oklahoma in May, 2003, examining these relations using in situ airborne measurements and surface-, airborne-, and space-based remote sensing.
New Modeling Approaches to Study DNA Damage by the Direct and Indirect Effects of Ionizing Radiation
NASA Technical Reports Server (NTRS)
Plante, Ianik; Cucinotta, Francis A.
2012-01-01
DNA is damaged both by the direct and indirect effects of radiation. In the direct effect, the DNA itself is ionized, whereas the indirect effect involves the radiolysis of the water molecules surrounding the DNA and the subsequent reaction of the DNA with radical products. While this problem has been studied for many years, many unknowns still exist. To study this problem, we have developed the computer code RITRACKS [1], which simulates the radiation track structure for heavy ions and electrons, calculating all energy deposition events and the coordinates of all species produced by the water radiolysis. In this work, we plan to simulate DNA damage by using the crystal structure of a nucleosome and calculations performed by RITRACKS. The energy deposition events are used to calculate the dose deposited in nanovolumes [2] and therefore can be used to simulate the direct effect of the radiation. Using the positions of the radiolytic species with a radiation chemistry code [3] it will be possible to simulate DNA damage by indirect effect. The simulation results can be compared with results from previous calculations such as the frequencies of simple and complex strand breaks [4] and with newer experimental data using surrogate markers of DNA double ]strand breaks such as . ]H2AX foci [5].
Air pollution and climate response to aerosol direct radiative ...
Decadal hemispheric Weather Research and Forecast-Community Multiscale Air Quality simulations from 1990 to 2010 were conducted to examine the meteorology and air quality responses to the aerosol direct radiative effects. The model's performance for the simulation of hourly surface temperature, relative humidity, wind speed, and direction was evaluated through comparison with observations from NOAA's National Climatic Data Center Integrated Surface Data. The inclusion of aerosol direct radiative effects improves the model's ability to reproduce the trend in daytime temperature range which over the past two decades was increasing in eastern China but decreasing in eastern U.S. and Europe. Trends and spatial and diurnal variations of the surface-level gaseous and particle concentrations to the aerosol direct effect were analyzed. The inclusion of aerosol direct radiative effects was found to increase the surface-level concentrations of SO2, NO2, O3, SO42−, NO3−, and particulate matter 2.5 in eastern China, eastern U.S., and Europe by 1.5–2.1%, 1–1.5%, 0.1–0.3%, 1.6–2.3%, 3.5–10.0%, and 2.2–3.2%, respectively, on average over the entire 21 year period. However, greater impacts are noted during polluted days with increases of 7.6–10.6%, 6.2–6.7%, 2.0–3.0%, 7.8–9.5%, 11.1–18.6%, and 7.2–10.1%, respectively. Due to the aerosol direct radiative effects, stabilizing of the atmosphere associated with reduced planetary boundary layer height a
Aerosol direct effects (ADE), i.e., scattering and absorption of incoming solar radiation, reduce radiation reaching the ground and the resultant photolysis attenuation can decrease O3 formation in polluted areas. One the other hand, evidence also suggests that ADE associated coo...
A comprehensive investigation of the processes regulating tropospheric aerosol distributions, their optical properties, and their radiative effects in conjunction with verification of their simulated radiative effects for past conditions relative to measurements is needed in orde...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dobrocky, Tomas, E-mail: tomas.dobrocky@insel.ch; Fuerstner, Markus, E-mail: markus.fuerstner@insel.ch; Klaeser, Bernd, E-mail: bernd.klaeser@insel.ch
2015-08-15
We herein present a patient undergoing selective internal radiation therapy with an almost normal lung shunt fraction of 11.5 %, developing histologically proven radiation pneumonitis. Due to a predominance of pulmonary consolidations in the right lower lung and its proximity to a large liver metastases located in the dome of the right liver lobe a Monte Carlo simulation was performed to estimate the effect of direct irradiation of the lung parenchyma. According to our calculations direct irradiation seems negligible and RP is almost exclusively due to ectopic draining of radioactive spheres.
A Global Modeling Study on Carbonaceous Aerosol Microphysical Characteristics and Radiative Effects
NASA Technical Reports Server (NTRS)
Bauer, S. E.; Menon, S.; Koch, D.; Bond, T. C.; Tsigaridis, K.
2010-01-01
Recently, attention has been drawn towards black carbon aerosols as a short-term climate warming mitigation candidate. However the global and regional impacts of the direct, indirect and semi-direct aerosol effects are highly uncertain, due to the complex nature of aerosol evolution and the way that mixed, aged aerosols interact with clouds and radiation. A detailed aerosol microphysical scheme, MATRIX, embedded within the GISS climate model is used in this study to present a quantitative assessment of the impact of microphysical processes involving black carbon, such as emission size distributions and optical properties on aerosol cloud activation and radiative effects. Our best estimate for net direct and indirect aerosol radiative flux change between 1750 and 2000 is -0.56 W/m2. However, the direct and indirect aerosol effects are quite sensitive to the black and organic carbon size distribution and consequential mixing state. The net radiative flux change can vary between -0.32 to -0.75 W/m2 depending on these carbonaceous particle properties at emission. Taking into account internally mixed black carbon particles let us simulate correct aerosol absorption. Absorption of black carbon aerosols is amplified by sulfate and nitrate coatings and, even more strongly, by organic coatings. Black carbon mitigation scenarios generally showed reduced radiative fluxeswhen sources with a large proportion of black carbon, such as diesel, are reduced; however reducing sources with a larger organic carbon component as well, such as bio-fuels, does not necessarily lead to a reduction in positive radiative flux.
A global modeling study on carbonaceous aerosol microphysical characteristics and radiative effects
NASA Astrophysics Data System (ADS)
Bauer, S. E.; Menon, S.; Koch, D.; Bond, T. C.; Tsigaridis, K.
2010-08-01
Recently, attention has been drawn towards black carbon aerosols as a short-term climate warming mitigation candidate. However the global and regional impacts of the direct, indirect and semi-direct aerosol effects are highly uncertain, due to the complex nature of aerosol evolution and the way that mixed, aged aerosols interact with clouds and radiation. A detailed aerosol microphysical scheme, MATRIX, embedded within the GISS climate model is used in this study to present a quantitative assessment of the impact of microphysical processes involving black carbon, such as emission size distributions and optical properties on aerosol cloud activation and radiative effects. Our best estimate for net direct and indirect aerosol radiative flux change between 1750 and 2000 is -0.56 W/m2. However, the direct and indirect aerosol effects are quite sensitive to the black and organic carbon size distribution and consequential mixing state. The net radiative flux change can vary between -0.32 to -0.75 W/m2 depending on these carbonaceous particle properties at emission. Taking into account internally mixed black carbon particles let us simulate correct aerosol absorption. Absorption of black carbon aerosols is amplified by sulfate and nitrate coatings and, even more strongly, by organic coatings. Black carbon mitigation scenarios generally showed reduced radiative fluxeswhen sources with a large proportion of black carbon, such as diesel, are reduced; however reducing sources with a larger organic carbon component as well, such as bio-fuels, does not necessarily lead to a reduction in positive radiative flux.
The Effects of Crosswind Flight on Rotor Harmonic Noise Radiation
NASA Technical Reports Server (NTRS)
Greenwood, Eric; Sim, Ben W.
2013-01-01
In order to develop recommendations for procedures for helicopter source noise characterization, the effects of crosswinds on main rotor harmonic noise radiation are assessed using a model of the Bell 430 helicopter. Crosswinds are found to have a significant effect on Blade-Vortex Interaction (BVI) noise radiation when the helicopter is trimmed with the fuselage oriented along the inertial flight path. However, the magnitude of BVI noise remains unchanged when the pilot orients the fuselage along the aerodynamic velocity vector, crabbing for zero aerodynamic sideslip. The effects of wind gradients on BVI noise are also investigated and found to be smaller in the crosswind direction than in the headwind direction. The effects of crosswinds on lower harmonic noise sources at higher flight speeds are also assessed. In all cases, the directivity of radiated noise is somewhat changed by the crosswind. The model predictions agree well with flight test data for the Bell 430 helicopter captured under various wind conditions. The results of this investigation would suggest that flight paths for future acoustic flight testing are best aligned across the prevailing wind direction to minimize the effects of winds on noise measurements when wind cannot otherwise be avoided.
Measurement of solar radiation at the Earth's surface
NASA Technical Reports Server (NTRS)
Bartman, F. L.
1982-01-01
The characteristics of solar energy arriving at the surface of the Earth are defined and the history of solar measurements in the United States presented. Radiation and meteorological measurements being made at solar energy meteorological research and training sites and calibration procedures used there are outlined. Data illustrating the annual variation in daily solar radiation at Ann Arbor, Michigan and the diurnal variation in radiation at Albuquerque, New Mexico are presented. Direct normal solar radiation received at Albuquerque is contrasted with that received at Maynard, Massachusetts. Average measured global radiation for a period of one year for four locations under clear skies, 50% cloud cover, and 100% cloud cover is given and compared with the solar radiation at the top of the atmosphere. The May distribution of mean daily direct solar radiation and mean daily global solar radiation over the United States is presented. The effects of turbidity on the direct and circumsolar radiation are shown.
Decadal hemispheric Weather Research and Forecast-Community Multiscale Air Quality simulations from 1990 to 2010 were conducted to examine the meteorology and air quality responses to the aerosol direct radiative effects. The model's performance for the simulation of hourly surfa...
While aerosol radiative effects have been recognized as some of the largest sources of uncertainty among the forcers of climate change, there has been little effort devoted to verification of the spatial and temporal variability of the magnitude and directionality of aerosol radi...
NASA Astrophysics Data System (ADS)
Rathod, T. D.; Sahu, S. K.; Tiwari, M.; Pandit, G. G.
2016-12-01
We report the enhancement in the direct radiative effect due the presence of Brown carbon (BrC) as a part of organic carbon aerosols. The optical properties of organic carbon aerosols generated from pyrolytic combustion of mango tree wood (Magnifera Indica) and dung cake at different temperatures were considered. Mie codes were used to calculate absorption and scattering coefficients coupled with experimentally derived imaginary complex refractive index. The direct radiative effect (DRE) for sampled organic carbon aerosols was estimated using a wavelength dependent radiative transfer equation. The BrC DRE was estimated taking virtually non absorbing organic aerosols as reference. The BrC DRE from wood and dung cake was compared at different combustion temperatures and conditions. The BrC contributed positively to the direct top of the atmosphere radiative effect. Dung cake generated BrC aerosols were found to be strongly light absorbing as compared to BrC from wood combustion. It was noted that radiative effects of BrC from wood depended on its generation temperature and conditions. For BrC aerosols from dung cake such strong dependence was not observed. The average BrC aerosol DRE values were 1.53±0.76 W g-1 and 17.84±6.45 W g-1 for wood and dung cake respectively. The DRE contribution of BrC aerosols came mainly (67-90%) from visible light absorption though they exhibited strong absorption in shorter wavelengths of the UV-visible spectrum.
Observationally constrained estimates of carbonaceous aerosol radiative forcing.
Chung, Chul E; Ramanathan, V; Decremer, Damien
2012-07-17
Carbonaceous aerosols (CA) emitted by fossil and biomass fuels consist of black carbon (BC), a strong absorber of solar radiation, and organic matter (OM). OM scatters as well as absorbs solar radiation. The absorbing component of OM, which is ignored in most climate models, is referred to as brown carbon (BrC). Model estimates of the global CA radiative forcing range from 0 to 0.7 Wm(-2), to be compared with the Intergovernmental Panel on Climate Change's estimate for the pre-Industrial to the present net radiative forcing of about 1.6 Wm(-2). This study provides a model-independent, observationally based estimate of the CA direct radiative forcing. Ground-based aerosol network data is integrated with field data and satellite-based aerosol observations to provide a decadal (2001 through 2009) global view of the CA optical properties and direct radiative forcing. The estimated global CA direct radiative effect is about 0.75 Wm(-2) (0.5 to 1.0). This study identifies the global importance of BrC, which is shown to contribute about 20% to 550-nm CA solar absorption globally. Because of the inclusion of BrC, the net effect of OM is close to zero and the CA forcing is nearly equal to that of BC. The CA direct radiative forcing is estimated to be about 0.65 (0.5 to about 0.8) Wm(-2), thus comparable to or exceeding that by methane. Caused in part by BrC absorption, CAs have a net warming effect even over open biomass-burning regions in Africa and the Amazon.
Observationally constrained estimates of carbonaceous aerosol radiative forcing
Chung, Chul E.; Ramanathan, V.; Decremer, Damien
2012-01-01
Carbonaceous aerosols (CA) emitted by fossil and biomass fuels consist of black carbon (BC), a strong absorber of solar radiation, and organic matter (OM). OM scatters as well as absorbs solar radiation. The absorbing component of OM, which is ignored in most climate models, is referred to as brown carbon (BrC). Model estimates of the global CA radiative forcing range from 0 to 0.7 Wm-2, to be compared with the Intergovernmental Panel on Climate Change’s estimate for the pre-Industrial to the present net radiative forcing of about 1.6 Wm-2. This study provides a model-independent, observationally based estimate of the CA direct radiative forcing. Ground-based aerosol network data is integrated with field data and satellite-based aerosol observations to provide a decadal (2001 through 2009) global view of the CA optical properties and direct radiative forcing. The estimated global CA direct radiative effect is about 0.75 Wm-2 (0.5 to 1.0). This study identifies the global importance of BrC, which is shown to contribute about 20% to 550-nm CA solar absorption globally. Because of the inclusion of BrC, the net effect of OM is close to zero and the CA forcing is nearly equal to that of BC. The CA direct radiative forcing is estimated to be about 0.65 (0.5 to about 0.8) Wm-2, thus comparable to or exceeding that by methane. Caused in part by BrC absorption, CAs have a net warming effect even over open biomass-burning regions in Africa and the Amazon. PMID:22753522
INDIRECT EFFECT OF X-RADIATION ON BONE GROWTH IN RATS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Conard, R.A.
1962-12-21
Effects of 200 to 600 r of x irradiation on tibial bone growth in groups of weanling male rats were studied by in vivo measurement of tibial bone growth in serial radiographs. By comparison of growth rates in shielded with unshielded legs, direct and indirect effects of radiation were demonstrated, both roughly dose dependent, but with the indirect effect being about twice that of the direct effect. Pair-feeding experiments showed that about 70% of the indirect effect was due to radiation-induced lowered food consumption. By partial-body shielding experiments, using pnir-fed controls, it was shown that the abdomen may be themore » site of a non-nutritional abscopal effect. (auth)« less
NASA Astrophysics Data System (ADS)
Kumar, A.; Pensia, R. K.
2018-05-01
This paper deals with the effect of rotation on the gravitational instability of optically thick magnetized quantum plasma in the presence of radiation. By using linearized perturbation equations of the problem, general dispersion relation is obtained which is reduced for longitudinal and transverse modes of propagation. For each mode, the problem is analyzed for two cases, when the direction of axis of rotation is parallel or perpendicular to the direction of magnetic field. Rotation parameter is found to modify the Jeans criterion of instability and expression for Jeans wavelength for transverse mode, when the axis of rotation is along the direction of magnetic field and it has stabilizing effect on the system. Magnetic field, radiation pressure and quantum correction also found to have stabilizing effect.
Impact of the 4 April 2014 Saharan dust outbreak on the photovoltaic power generation in Germany
NASA Astrophysics Data System (ADS)
Rieger, Daniel; Steiner, Andrea; Bachmann, Vanessa; Gasch, Philipp; Förstner, Jochen; Deetz, Konrad; Vogel, Bernhard; Vogel, Heike
2017-11-01
The importance for reliable forecasts of incoming solar radiation is growing rapidly, especially for those countries with an increasing share in photovoltaic (PV) power production. The reliability of solar radiation forecasts depends mainly on the representation of clouds and aerosol particles absorbing and scattering radiation. Especially under extreme aerosol conditions, numerical weather prediction has a systematic bias in the solar radiation forecast. This is caused by the design of numerical weather prediction models, which typically account for the direct impact of aerosol particles on radiation using climatological mean values and the impact on cloud formation assuming spatially and temporally homogeneous aerosol concentrations. These model deficiencies in turn can lead to significant economic losses under extreme aerosol conditions. For Germany, Saharan dust outbreaks occurring 5 to 15 times per year for several days each are prominent examples for conditions, under which numerical weather prediction struggles to forecast solar radiation adequately. We investigate the impact of mineral dust on the PV-power generation during a Saharan dust outbreak over Germany on 4 April 2014 using ICON-ART, which is the current German numerical weather prediction model extended by modules accounting for trace substances and related feedback processes. We find an overall improvement of the PV-power forecast for 65 % of the pyranometer stations in Germany. Of the nine stations with very high differences between forecast and measurement, eight stations show an improvement. Furthermore, we quantify the direct radiative effects and indirect radiative effects of mineral dust. For our study, direct effects account for 64 %, indirect effects for 20 % and synergistic interaction effects for 16 % of the differences between the forecast including mineral dust radiative effects and the forecast neglecting mineral dust.
Radionuclides in radiation-induced bystander effect; may it share in radionuclide therapy?
Widel, M
2017-01-01
For many years in radiobiology and radiotherapy predominated the conviction that cellular DNA is the main target for ionizing radiation, however, the view has changed in the past 20 years. Nowadays, it is assumed that not only directed (targeted) radiation effect, but also an indirect (non-targeted) effect may contribute to the result of radiation treatment. Non-targeted effect is relatively well recognized after external beam irradiation in vitro and in vivo, and comprises such phenomena like radiation-induced bystander effect (RIBE), genomic instability, adaptive response and abscopal (out of field) effect. These stress-induced and molecular signaling mediated phenomena appear in non-targeted cells as variety responses resembling that observed in directly hit cells. Bystander effects can be both detrimental and beneficial in dependence on dose, dose-rate, cell type, genetic status and experimental condition. Less is known about radionuclide-induced non-targeted effects in radionuclide therapy, although, based on characteristics of the radionuclide radiation, on experiments in vitro utilizing classical and 3-D cell cultures, and preclinical study on animals it seems obvious that exposure to radionuclide is accompanied by various bystander effects, mostly damaging, less often protective. This review summarizes existing data on radionuclide induced bystander effects comprising radionuclides emitting beta- and alpha-particles and Auger electrons used in tumor radiotherapy and diagnostics. So far, separation of the direct effect of radionuclide decay from crossfire and bystander effects in clinical targeted radionuclide therapy is impossible because of the lack of methods to assess whether, and to what extent bystander effect is involved in human organism. Considerations on this topic are also included.
Direct and indirect effects of ionizing radiation on grazer-phytoplankton interactions.
Nascimento, Francisco J A; Bradshaw, Clare
2016-05-01
Risk assessment of exposure to radionuclides and radiation does not usually take into account the role of species interactions. We investigated how the transfer of carbon between a primary producer, Raphidocelis subcapitata, and a consumer, Daphnia magna, was affected by acute exposure to gamma radiation. In addition to unexposed controls, different treatments were used where: a) only D. magna (Z treatment); b) only R. subcapitata (P treatment) and c) both D. magna and R. subcapitata (ZP treatment) were exposed to one of three acute doses of gamma radiation (5, 50 and 100 Gy). We then compared differences among treatments for three endpoints: incorporation of carbon by D. magna, D. magna growth and R. subcapitata densities. Carbon incorporation was affected by which combination of species was irradiated and by the radiation dose. Densities of R. subcapitata at the end of the experiment were also affected by which species had been exposed to radiation. Carbon incorporation by D. magna was significantly lower in the Z treatment, indicating reduced grazing, an effect stronger with higher radiation doses, possibly due to direct effects of gamma radiation. Top-down indirect effects of this reduced grazing were also seen as R. subcapitata densities increased in the Z treatment due to decreased herbivory. The opposite pattern was observed in the P treatment where only R. subcapitata was exposed to gamma radiation, while the ZP treatment showed intermediate results for both endpoints. In the P treatments, carbon incorporation by D. magna was significantly higher than in the other treatments, suggesting a higher grazing pressure. This, together with direct effects of gamma radiation on R. subcapitata, probably significantly decreased phytoplankton densities in the P treatment. Our results highlight the importance of taking into account the role of species interactions when assessing the effects of exposure to gamma radiation in aquatic ecosystems. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
Method for microbeam radiation therapy
Slatkin, Daniel N.; Dilmanian, F. Avraham; Spanne, Per O.
1994-01-01
A method of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation, in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue.
Method for microbeam radiation therapy
Slatkin, D.N.; Dilmanian, F.A.; Spanne, P.O.
1994-08-16
A method is disclosed of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation. The dose is in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue. No Drawings
Towards quantifying global aerosol radiative effects using lidar
NASA Astrophysics Data System (ADS)
Thorsen, T. J.
2017-12-01
Spaceborne lidar observations alleviate many of the limitations of passivesensors and have great potential to provide accurate global all-sky estimatesof the aerosol direct radiative effect (DRE). However, analysis of CALIPSOlidar observations show that CALIPSO does not detect allradiatively-significant aerosol, i.e. aerosol that directly modifies theEarth's radiation budget. We estimated that using CALIPSO observationsresults in an underestimate of the magnitude of the global mean aerosol DREby up to 54%. The CATS lidar on-board the ISS is shown to have a poorersensitivity than CALIPSO and the expected sensitivity of the upcoming ATLIDlidar on EarthCARE indicates that calculations of the aerosol DRE willcontinue to be significantly biased. Improvements to our knowledge of aerosol forcing, which contributes thelargest uncertainty to climate sensitivity, could be achieved by a futurespace-based HSRL mission. To this end, high-accuracy ground-based andairborne lidar datasets have been used to compute the detection sensitivityrequired to accurately resolve the aerosol DRE. Multiwavelength HSRLmeasurements also can retrieve vertically-resolved aerosol optical propertiesneeded for radiative transfer calculations which are not provided by currentsatellite observations. Current satellite observations also do not provideall the quantities needed to compute the aerosol direct radiative forcing,i.e. the radiative effect of just anthropogenic aerosols. A multiwavelengthHSRL allows for a more refined aerosol classification to be made enablingboth calculations of anthropogenic aerosol radiative effects and betterconstraints on global models.
NASA Astrophysics Data System (ADS)
Cochrane, S.; Schmidt, S.; Chen, H.; Pilewskie, P.; Redemann, J.; LeBlanc, S. E.; Platnick, S. E.; Meyer, K.; Ferrare, R. A.; Burton, S. P.; Hostetler, C. A.; Iwabuchi, H.
2017-12-01
The Southeast Atlantic contains a large, semi-permanent cloud deck often overlaid by a thick layer of biomass burning aerosols that has been advected westward from Southern Africa. We will present (a) the direct aerosol radiative effect (b) the albedo value for which the radiative effect transitions from warming to cooling, i.e., the critical albedo, and (c) aerosol and gas absorption and heating rates for this region from the 2016 and 2017 deployments of the NASA ORACLES experiment (ObseRvations of CLouds above Aerosols and their intEractionS). Observations by the Solar Spectral Flux Radiometer (SSFR), Enhanced MODIS Airborne Simulator (eMAS), High Spectral Resolution Lidar (HSRL-2,) and the Spectrometer for Sky-Scanning Sun-Tracking Atmospheric Research (4STAR) are put into context by the 3D radiative transfer model Monte Carlo Atmospheric Radiative Transfer Simulator (MCARaTS), which allows us to determine the aerosol radiative effect especially when inhomogeneous clouds are present. For highly homogeneous scenes, a direct derivation from the measurements is also possible. We give an overview of spectral single scattering albedo, Ångström exponents, and heating rate profiles for the two experiments while also exploring the dependence of the critical albedo on the aerosol properties.
Van Arnem, Kerri A; Supinski, David P; Tucker, Jonathan E; Varney, Shawn
2016-12-01
Trauma patients sustaining blunt injuries are exposed to multiple radiologic studies. Evidence indicates that the risk of cancer from exposure to ionizing radiation rises in direct proportion to the cumulative effective dose (CED) received. The purpose of this study is to quantify the amount of ionizing radiation accumulated when arriving directly from point of injury to San Antonio Military Medical Center (SAMMC), a level I trauma center, compared with those transferred from other facilities. A retrospective record review was conducted from 1st January 2010 through 31st December 2012. The SAMMC trauma registry, electronic medical records, and the digital radiology imaging system were searched for possible candidates. The medical records were then analyzed for sex, age, mechanism of injury, received directly from point of injury (direct group), transfer from another medical facility (transfer group), computed tomographic scans received, dose-length product, CED of radiation, and injury severity score. A diagnostic imaging physicist then calculated the estimated CED each subject received based on the dose-length product of each computed tomographic scan. A total of 300 patients were analyzed, with 150 patients in the direct group and 150 patients in the transfer group. Both groups were similar in age and sex. Patients in the transfer group received a significantly greater CED of radiation compared with the direct group (mean, 37.6 mSv vs 28 mSv; P=.001). The radiation received in the direct group correlates with a lifetime attributable risk (LAR) of 1 in 357 compared with the transfer group with an increase in LAR to 1 in 266. Patients transferred to our facility received a 34% increase in ionizing radiation compared with patients brought directly from the injury scene. This increased dose of ionizing radiation contributes to the LAR of cancer and needs to be considered before repeating imaging studies. III. Published by Elsevier Inc.
Compton effect thermally activated depolarization dosimeter
Moran, Paul R.
1978-01-01
A dosimetry technique for high-energy gamma radiation or X-radiation employs the Compton effect in conjunction with radiation-induced thermally activated depolarization phenomena. A dielectric material is disposed between two electrodes which are electrically short circuited to produce a dosimeter which is then exposed to the gamma or X radiation. The gamma or X-radiation impinging on the dosimeter interacts with the dielectric material directly or with the metal composing the electrode to produce Compton electrons which are emitted preferentially in the direction in which the radiation was traveling. A portion of these electrons becomes trapped in the dielectric material, consequently inducing a stable electrical polarization in the dielectric material. Subsequent heating of the exposed dosimeter to the point of onset of ionic conductivity with the electrodes still shorted through an ammeter causes the dielectric material to depolarize, and the depolarization signal so emitted can be measured and is proportional to the dose of radiation received by the dosimeter.
NASA Astrophysics Data System (ADS)
Nabat, Pierre; Somot, Samuel; Mallet, Marc; Sevault, Florence; Chiacchio, Marc; Wild, Martin
2015-02-01
A fully coupled regional climate system model (CNRM-RCSM4) has been used over the Mediterranean region to investigate the direct and semi-direct effects of aerosols, but also their role in the radiation-atmosphere-ocean interactions through multi-annual ensemble simulations (2003-2009) with and without aerosols and ocean-atmosphere coupling. Aerosols have been taken into account in CNRM-RCSM4 through realistic interannual monthly AOD climatologies. An evaluation of the model has been achieved, against various observations for meteorological parameters, and has shown the ability of CNRM-RCSM4 to reproduce the main patterns of the Mediterranean climate despite some biases in sea surface temperature (SST), radiation and cloud cover. The results concerning the aerosol radiative effects show a negative surface forcing on average because of the absorption and scattering of the incident radiation. The SW surface direct effect is on average -20.9 Wm-2 over the Mediterranean Sea, -14.7 Wm-2 over Europe and -19.7 Wm-2 over northern Africa. The LW surface direct effect is weaker as only dust aerosols contribute (+4.8 Wm-2 over northern Africa). This direct effect is partly counterbalanced by a positive semi-direct radiative effect over the Mediterranean Sea (+5.7 Wm-2 on average) and Europe (+5.0 Wm-2) due to changes in cloud cover and atmospheric circulation. The total aerosol effect is consequently negative at the surface and responsible for a decrease in land (on average -0.4 °C over Europe, and -0.5 °C over northern Africa) and sea surface temperature (on average -0.5 °C for the Mediterranean SST). In addition, the latent heat loss is shown to be weaker (-11.0 Wm-2) in the presence of aerosols, resulting in a decrease in specific humidity in the lower troposphere, and a reduction in cloud cover and precipitation. Simulations also indicate that dust aerosols warm the troposphere by absorbing solar radiation, and prevent radiation from reaching the surface, thus stabilizing the troposphere. The comparison with the model response in atmosphere-only simulations shows that these feedbacks are attenuated if SST cannot be modified by aerosols, highlighting the importance of using coupled regional models over the Mediterranean. Oceanic convection is also strengthened by aerosols, which tends to reinforce the Mediterranean thermohaline circulation. In parallel, two case studies are presented to illustrate positive feedbacks between dust aerosols and regional climate. First, the eastern Mediterranean was subject to high dust aerosol loads in June 2007 which reduce land and sea surface temperature, as well as air-sea humidity fluxes. Because of northern wind over the eastern Mediterranean, drier and cooler air has been consequently advected from the sea to the African continent, reinforcing the direct dust effect over land. On the contrary, during the western European heat wave in June 2006, dust aerosols have contributed to reinforcing an important ridge responsible for dry and warm air advection over western Europe, and thus to increasing lower troposphere (+0.8 °C) and surface temperature (+0.5 °C), namely about 15 % of this heat wave.
2009-01-01
Ste B-100 Directed Energy Bioeffects Division San Antonio, TX 78228 Optical Radiation Branch 2624 Louis Bauer Dr. Brooks City-Base, TX...S) Air Force Research Laboratory Human Effectiveness Directorate Directed Energy Bioeffects Division Optical Radiation Branch 2624 Louis Bauer Dr...Research Laboratory, 711th HPW, Optical Radiation Branch, 2624 Louis Bauer Dr., Brooks City-Base, Texas 78231 3Northrop Grumman, 4241 Woodcock Dr. Ste. B
NASA Astrophysics Data System (ADS)
Mathur, R.; Pleim, J.; Wong, D.; Wei, C.; Xing, J.; Gan, M.; Yu, S.; Binkowski, F.
2012-12-01
While aerosol radiative effects have been recognized as some of the largest sources of uncertainty among the forcers of climate change, there has been little effort devoted to verification of the spatial and temporal variability of the magnitude and directionality of aerosol radiative forcing. A comprehensive investigation of the processes regulating aerosol distributions, their optical properties, and their radiative effects and verification of their simulated effects for past conditions relative to measurements is needed in order to build confidence in the estimates of the projected impacts arising from changes in both anthropogenic forcing and climate change. This study aims at addressing this issue through a systematic investigation of changes in anthropogenic emissions of SO2 and NOx over the past two decades in the United States, their impacts on anthropogenic aerosol loading in the North American troposphere, and subsequent impacts on regional radiation budgets. A newly developed 2-way coupled meteorology and air pollution model composed of the Weather Research and Forecasting (WRF) model and the Community Multiscale Air Quality (CMAQ) model is being run for 20 years (1990 - 2010) on a 12 km resolution grid that covers most of North America including the entire conterminous US. During this period US emissions of SO2 and NOx have been reduced by about 66% and 50%, respectively, mainly due to Title IV of the U.S. Clean Air Act Amendments (CAA) that aimed to reduce emissions that contribute to acid deposition. A methodology is developed to consistently estimate emission inventories for the 20-year period accounting for air quality regulations as well as population trends, economic conditions, and technology changes in motor vehicles and electric power generation. The coupled WRF-CMAQ model includes detailed treatment of direct effects of aerosols on photolysis rates as well as on shortwave radiation and the direct effects of tropospheric ozone on the long-wave. New algorithms for the calculation of aerosol optical properties and radiation have been developed by considering both computational efficiency and more realistic aerosol states. Additionally, treatment of aerosol indirect effects on clouds has also recently been implemented. Analysis of measurements of aerosol composition, radiation, and associated variables, over the past two decades will be presented which indicate significant reductions in the tropospheric aerosol burden as well as an increase in down-welling shortwave radiation at numerous sites across the U.S. Initial applications of the coupled WRF-CMAQ model for time-periods pre and post the implementation of Title IV of the CAA will be discussed and comparisons with measurements to assess the model's ability to capture trends in aerosol burden, composition, and direct aerosol effects on surface shortwave radiation will be presented.
Solar radiation on Mars: Update 1991
NASA Technical Reports Server (NTRS)
Appelbaum, Joseph; Landis, Geoffrey A.
1991-01-01
Detailed information on solar radiation characteristics on Mars are necessary for effective design of future planned solar energy systems operating on the surface of Mars. A procedure and solar radiation related data are presented from which the daily variation of the global, direct beam and diffuse insolation on Mars are calculated. Given the optical depth of the Mars atmosphere, the global radiation is calculated from the normalized net flux function based on multiple wavelength and multiple scattering of the solar radiation. The direct beam was derived from the optical depth using Beer's law, and the diffuse component was obtained from the difference of the global and the direct beam radiation. The optical depths of the Mars atmosphere were derived from images taken of the Sun with a special diode on the cameras used on the two Viking Landers.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gu, Lianhong; Meyers, T. P.; Pallardy, Stephen G.
2006-01-01
The purpose of this paper is to examine the mechanism that controls the variation of surface energy partitioning between latent and sensible heat fluxes at a temperate deciduous forest site in central Missouri, USA. Taking advantage of multiple micrometeorological and ecophysiological measurements and a prolonged drought in the middle of the 2005 growing season at this site, we studied how soil moisture, atmospheric vapor pressure deficit (VPD), and net radiation affected surface energy partitioning. We stratified these factors to minimize potential confounding effects of correlation among them. We found that all three factors had direct effects on surface energy partitioning,more » but more important, all three factors also had crucial indirect effects. The direct effect of soil moisture was characterized by a rapid decrease in Bowen ratio with increasing soil moisture when the soil was dry and by insensitivity of Bowen ratio to variations in soil moisture when the soil was wet. However, the rate of decrease in Bowen ratio when the soil was dry and the level of soil moisture above which Bowen ratio became insensitive to changes in soil moisture depended on atmospheric conditions. The direct effect of increased net radiation was to increase Bowen ratio. The direct effect of VPD was very nonlinear: Increased VPD decreased Bowen ratio at low VPD but increased Bowen ratio at high VPD. The indirect effects were much more complicated. Reduced soil moisture weakened the influence of VPD but enhanced the influence of net adiation on surface energy partitioning. Soil moisture also controlled how net radiation influenced the relationship between surface energy partitioning and VPD and how VPD affected the relationship between surface energy partitioning and net radiation. Furthermore, both increased VPD and increased net radiation enhanced the sensitivity of Bowen ratio to changes in soil moisture and the effect of drought on surface energy partitioning. The direct and indirect effects of atmospheric conditions and soil moisture on surface energy partitioning identified in this paper provide a target for testing atmospheric general circulation models in their representation of land-atmosphere coupling.« less
NASA Technical Reports Server (NTRS)
Kim, M.Y.; Cucinotta, F.A.
2005-01-01
Radiation protection practices define the effective dose as a weighted sum of equivalent dose over major sites for radiation cancer risks. Since a crew personnel dosimeter does not make direct measurement of effective dose, it has been estimated with skin-dose measurements and radiation transport codes for ISS and STS missions. The Phantom Torso Experiment (PTE) of NASA s Operational Radiation Protection Program has provided the actual flight measurements of active and passive dosimeters which were placed throughout the phantom on STS-91 mission for 10 days and on ISS Increment 2 mission. For the PTE, the variation in organ doses, which is resulted by the absorption and the changes in radiation quality with tissue shielding, was considered by measuring doses at many tissue sites and at several critical body organs including brain, colon, heart, stomach, thyroid, and skins. These measurements have been compared with the organ dose calculations obtained from the transport models. Active TEPC measurements of lineal energy spectra at the surface of the PTE also provided the direct comparison of galactic cosmic ray (GCR) or trapped proton dose and dose equivalent. It is shown that orienting the phantom body as actual in ISS is needed for the direct comparison of the transport models to the ISS data. One of the most important observations for organ dose equivalent of effective dose estimates on ISS is the fractional contribution from trapped protons and GCR. We show that for most organs over 80% is from GCR. The improved estimation of effective doses for radiation cancer risks will be made with the resultant tissue weighting factors and the modified codes.
Direct and semidirect aerosol effects of southern African biomass burning aerosol
NASA Astrophysics Data System (ADS)
Sakaeda, Naoko; Wood, Robert; Rasch, Philip J.
2011-06-01
Direct and semidirect radiative effects of biomass burning aerosols from southern African fires during July-October are investigated using 20 year runs of the Community Atmospheric Model (CAM) coupled to a slab ocean model. Aerosol optical depth is constrained using observations in clear skies from Moderate Resolution Imaging Spectroradiometer (MODIS) and for aerosol layers above clouds from Cloud Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO). Over the ocean, where the aerosol layers are primarily located above cloud, negative top of atmosphere (TOA) semidirect radiative effects associated with increased low cloud cover dominate over a weaker positive all-sky direct radiative effect (DRE). In contrast, over the land where the aerosols are often below or within cloud layers, reductions in cloud liquid water path (LWP) lead to a positive semidirect radiative effect that dominates over a near-zero DRE. Over the ocean, the cloud response can be understood as a response to increased lower tropospheric stability (LTS) which is caused both by radiative heating in overlying layers and surface cooling in response to direct aerosol forcing. The marine cloud changes are robust to changes in the cloud parameterization (removal of the hard-wired dependence of clouds on LTS), suggesting that they are physically realistic. Over land, decreased LWP is consistent with weaker convection driven by increased static stability. Over the entire region the overall TOA radiative effect from the biomass burning aerosols is almost zero due to opposing effects over the land and ocean. However, the surface forcing is strongly negative, which leads to a reduction in precipitation and also a reduction in sensible heat flux. The former is primarily realized through reductions in convective precipitation on both the southern and northern flanks of the convective precipitation region spanning the equatorial rain forest and the Intertropical Convergence Zone (ITCZ) in the southern Sahel. The changes are consistent with the low-level aerosol-forced cooling pattern. The results highlight the importance of semidirect radiative effects and precipitation responses for determining the climatic effects of aerosols in the African region.
NASA Astrophysics Data System (ADS)
Lu, Zheng; Liu, Xiaohong; Zhang, Zhibo; Zhao, Chun; Meyer, Kerry; Rajapakshe, Chamara; Wu, Chenglai; Yang, Zhifeng; Penner, Joyce E.
2018-03-01
Marine stratocumulus clouds cover nearly one-quarter of the ocean surface and thus play an extremely important role in determining the global radiative balance. The semipermanent marine stratocumulus deck over the southeastern Atlantic Ocean is of particular interest, because of its interactions with seasonal biomass burning aerosols that are emitted in southern Africa. Understanding the impacts of biomass burning aerosols on stratocumulus clouds and the implications for regional and global radiative balance is still very limited. Previous studies have focused on assessing the magnitude of the warming caused by solar scattering and absorption by biomass burning aerosols over stratocumulus (the direct radiative effect) or cloud adjustments to the direct radiative effect (the semidirect effect). Here, using a nested modeling approach in conjunction with observations from multiple satellites, we demonstrate that cloud condensation nuclei activated from biomass burning aerosols entrained into the stratocumulus (the microphysical effect) can play a dominant role in determining the total radiative forcing at the top of the atmosphere, compared with their direct and semidirect radiative effects. Biomass burning aerosols over the region and period with heavy loadings can cause a substantial cooling (daily mean ‑8.05 W m‑2), primarily as a result of clouds brightening by reducing the cloud droplet size (the Twomey effect) and secondarily through modulating the diurnal cycle of cloud liquid water path and coverage (the cloud lifetime effect). Our results highlight the importance of realistically representing the interactions of stratocumulus with biomass burning aerosols in global climate models in this region.
Observed Reduction In Surface Solar Radiation - Aerosol Forcing Versus Cloud Feedback?
NASA Astrophysics Data System (ADS)
Liepert, B.
The solar radiation reaching the ground is a key parameter for the climate system. It drives the hydrological cycle and numerous biological processes. Surface solar radi- ation revealed an estimated 7W/m2 or 4% decline at sites worldwide from 1961 to 1990. The strongest decline occurred at the United States sites with 19W/m2 or 10%. Increasing air pollution and hence direct and indirect aerosol effect, as we know today can only explain part of the reduction in solar radiation. Increasing cloud optical thick- ness - possibly due to global warming - is a more likely explanation for the observed reduction in solar radiation in the United States. The analysis of surface solar radiation data will be shown and compared with GCM results of the direct and indirect aerosol effect. It will be argued that the residual declines in surface solar radiation is likely due to cloud feedback.
Effects of solar radiation on glass
NASA Technical Reports Server (NTRS)
Tucker, Dennis S.; Kinser, Donald L.
1991-01-01
The effects of solar radiation of selected glasses are reported. Optical property degradation is studied using UV-Vis spectrophotometry. Strength changes are measured using a concentric ring bend test. Direct fracture toughness measurements using an indentation test are planned.
Assurance Against Radiation Effects on Electronics
NASA Technical Reports Server (NTRS)
LaBel, Kenneth A.
2004-01-01
Contents include the following: The Space Radiation Environment. The Effects on Electronics. The Environment in Action. NASA Approaches to Commercial Electronics: the mission mix, flight projects, and proactive research. Final Thoughts: atomic interactions, direct ionization, interaction with nucleus.
CDUCT-LaRC Status - Shear Layer Refraction and Noise Radiation
NASA Technical Reports Server (NTRS)
Nark, Douglas M.; Farassat, F.
2006-01-01
A proposed boundary condition accounting for shear layer effects within the Ffowcs Williams-Hawkings radiation module of the CDUCT-LaRC code is investigated. The development and numerical justification of the boundary condition formulation are reviewed. An initial assessment of the effectiveness of the shear layer correction is conducted through comparison with experimental data. Preliminary results indicate that the correction provides physically meaningful modifications of the baseline predicted directivity patterns. Trends of peak directivity steepening and shifting that appeared in predicted patterns were found to follow similar structures in measured data, particularly at higher radiation angles.
Aerosol Microphysical and Radiative Effects on Continental Cloud Ensembles
Wang, Yuan; Vogel, Jonathan M.; Lin, Yun; ...
2018-01-10
Aerosol-cloud-radiation interactions represent one of the largest uncertainties in the current climate assessment. Much of the complexity arises from the non-monotonic responses of clouds, precipitation and radiative fluxes to aerosol perturbations under various meteorological conditions. Here, an aerosol-aware Weather Research and Forecasting (WRF) model is used to investigate the microphysical and radiative effects of aerosols in three weather systems during the March 2000 Cloud Intensive Observational Period campaign at the Southern Great Plains site of the US Atmospheric Radiation Measurement Program. Three cloud ensembles with different meteorological conditions are simulated, including a low-pressure deep convective cloud system, a series ofmore » lessprecipitating stratus and shallow cumulus, and a cold frontal passage. The WRF simulations are evaluated by the available observations of cloud fraction, liquid water path, precipitation, and surface temperature. The microphysical properties of cloud hydrometeors, such as their mass and number concentrations, generally show monotonic trends as a function of cloud condensation nuclei concentrations. Aerosol radiative effects do not interfere the trends of cloud microphysics, except for the stratus and shallow cumulus cases where aerosol semi-direct effects are identified. The precipitation changes by aerosols vary with the cloud types and their evolving stages, with more prominent aerosol invigoration effect and associated enhanced precipitation from the convective sources. Furthermore, the simulated aerosol direct effect suppresses precipitation in all three cases but does not overturn the direction of precipitation changes by the aerosol indirect effect. Cloud fraction exhibits much smaller sensitivity (typically less than 2%) to aerosol perturbations than the cloud microphysics, and the responses vary with aerosol concentrations and cloud regimes. The surface shortwave radiation shows a monotonic decrease by increasing aerosols, while the magnitude of the decrease depends on the cloud type. Surface temperature changes closely follow the modulation of the surface radiation fluxes.« less
Aerosol Microphysical and Radiative Effects on Continental Cloud Ensembles
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, Yuan; Vogel, Jonathan M.; Lin, Yun
Aerosol-cloud-radiation interactions represent one of the largest uncertainties in the current climate assessment. Much of the complexity arises from the non-monotonic responses of clouds, precipitation and radiative fluxes to aerosol perturbations under various meteorological conditions. Here, an aerosol-aware Weather Research and Forecasting (WRF) model is used to investigate the microphysical and radiative effects of aerosols in three weather systems during the March 2000 Cloud Intensive Observational Period campaign at the Southern Great Plains site of the US Atmospheric Radiation Measurement Program. Three cloud ensembles with different meteorological conditions are simulated, including a low-pressure deep convective cloud system, a series ofmore » lessprecipitating stratus and shallow cumulus, and a cold frontal passage. The WRF simulations are evaluated by the available observations of cloud fraction, liquid water path, precipitation, and surface temperature. The microphysical properties of cloud hydrometeors, such as their mass and number concentrations, generally show monotonic trends as a function of cloud condensation nuclei concentrations. Aerosol radiative effects do not interfere the trends of cloud microphysics, except for the stratus and shallow cumulus cases where aerosol semi-direct effects are identified. The precipitation changes by aerosols vary with the cloud types and their evolving stages, with more prominent aerosol invigoration effect and associated enhanced precipitation from the convective sources. Furthermore, the simulated aerosol direct effect suppresses precipitation in all three cases but does not overturn the direction of precipitation changes by the aerosol indirect effect. Cloud fraction exhibits much smaller sensitivity (typically less than 2%) to aerosol perturbations than the cloud microphysics, and the responses vary with aerosol concentrations and cloud regimes. The surface shortwave radiation shows a monotonic decrease by increasing aerosols, while the magnitude of the decrease depends on the cloud type. Surface temperature changes closely follow the modulation of the surface radiation fluxes.« less
Though aerosol radiative effects have been recognized as some of the largest sources of uncertainty among the forcers of climate change, the verification of the spatial and temporal variability of the magnitude and directionality of aerosol radiative forcing has remained challeng...
Global Aerosol Direct Radiative Effect From CALIOP and C3M
NASA Technical Reports Server (NTRS)
Winker, Dave; Kato, Seiji; Tackett, Jason
2015-01-01
Aerosols are responsible for the largest uncertainties in current estimates of climate forcing. These uncertainties are due in part to the limited abilities of passive sensors to retrieve aerosols in cloudy skies. We use a dataset which merges CALIOP observations together with other A-train observations to estimate aerosol radiative effects in cloudy skies as well as in cloud-free skies. The results can be used to quantify the reduction of aerosol radiative effects in cloudy skies relative to clear skies and to reduce current uncertainties in aerosol radiative effects.
Global Aerosol Direct Radiative Effect from CALIOP and C3M
NASA Technical Reports Server (NTRS)
Winker, Dave; Kato, Seiji; Tackett, Jason
2015-01-01
Aerosols are responsible for the largest uncertainties in current estimates of climate forcing. These uncertainties are due in part to the limited abilities of passive sensors to retrieve aerosols in cloudy skies. We use a dataset which merges CALIOP observations together with other A-train observations to estimate aerosol radiative effects in cloudy skies as well as in cloud-free skies. The results can be used to quantify the reduction of aerosol radiative effects in cloudy skies relative to clear skies and to reduce current uncertainties in aerosol radiative effects.
Redox-Modulated Phenomena and Radiation Therapy: The Central Role of Superoxide Dismutases
Holley, Aaron K.; Miao, Lu; St. Clair, Daret K.
2014-01-01
Abstract Significance: Ionizing radiation is a vital component in the oncologist's arsenal for the treatment of cancer. Approximately 50% of all cancer patients will receive some form of radiation therapy as part of their treatment regimen. DNA is considered the major cellular target of ionizing radiation and can be damaged directly by radiation or indirectly through reactive oxygen species (ROS) formed from the radiolysis of water, enzyme-mediated ROS production, and ROS resulting from altered aerobic metabolism. Recent Advances: ROS are produced as a byproduct of oxygen metabolism, and superoxide dismutases (SODs) are the chief scavengers. ROS contribute to the radioresponsiveness of normal and tumor tissues, and SODs modulate the radioresponsiveness of tissues, thus affecting the efficacy of radiotherapy. Critical Issues: Despite its prevalent use, radiation therapy suffers from certain limitations that diminish its effectiveness, including tumor hypoxia and normal tissue damage. Oxygen is important for the stabilization of radiation-induced DNA damage, and tumor hypoxia dramatically decreases radiation efficacy. Therefore, auxiliary therapies are needed to increase the effectiveness of radiation therapy against tumor tissues while minimizing normal tissue injury. Future Directions: Because of the importance of ROS in the response of normal and cancer tissues to ionizing radiation, methods that differentially modulate the ROS scavenging ability of cells may prove to be an important method to increase the radiation response in cancer tissues and simultaneously mitigate the damaging effects of ionizing radiation on normal tissues. Altering the expression or activity of SODs may prove valuable in maximizing the overall effectiveness of ionizing radiation. Antioxid. Redox Signal. 20, 1567–1589. PMID:24094070
Estimation of Aerosol Direct Radiative Effects from Satellite and In Situ Measurements
NASA Technical Reports Server (NTRS)
Bergstrom, Robert W.; Russell, Philip B.; Schmid, Beat; Redemann, Jens; McIntosh, Dawn
2000-01-01
Ames researchers have combined measurements from satellite, aircraft, and the surface to estimate the effect of airborne particles (aerosols) on the solar radiation over the North Atlantic region. These aerosols (which come from both natural and pollution sources) can reflect solar radiation, causing a cooling effect that opposes the warming caused by carbon dioxide. Recently, increased attention has been paid to aerosol effects to better understand the Earth climate system.
Rays Sting: The Acute Cellular Effects of Ionizing Radiation Exposure
Franco, A; Ciccarelli, M; Sorriento, D; Napolitano, L; Fiordelisi, A; Trimarco, B; Durante, M; Iaccarino, G
2016-01-01
High-precision radiation therapy is a clinical approach that uses the targeted delivery of ionizing radiation, and the subsequent formation of reactive oxygen species (ROS) in high proliferative, radiation sensitive cancers. In particular, in thoracic cancer ratdiation treatments, can not avoid a certain amount of cardiac toxicity. Given the low proliferative rate of cardiac myocytes, research has looked at the effect of radiation on endothelial cells and consequent coronary heart disease as the mechanism of ratdiation induced cardiotoxicity. In fact, little is known concerning the direct effect of radiation on mitochondria dynamis in cardiomyocyte. The main effect of ionizing radiation is the production of ROS and recent works have uncovered that they directly participates to pivotal cell function like mitochondrial quality control. In particular ROS seems to act as check point within the cell to promote either mitochondrial biogenesis and survival or mitochondrial damage and apoptosis. Thus, it appears evident that the functional state of the cell, as well as the expression patterns of molecules involved in mitochondrial metabolism may differently modulate mitochondrial fate in response to radiation induced ROS responses. Different molecules have been described to localize to mitochondria and regulate ROS production in response to stress, in particular GRK2. In this review we will discuss the evidences on the cardiac toxicity induced by X ray radiation on cardiomyocytes with emphasis on the role played by mitochondria dynamism. PMID:27326395
Kume, Atsushi
2017-05-01
Terrestrial green plants absorb photosynthetically active radiation (PAR; 400-700 nm) but do not absorb photons evenly across the PAR waveband. The spectral absorbance of photosystems and chloroplasts is lowest for green light, which occurs within the highest irradiance waveband of direct solar radiation. We demonstrate a close relationship between this phenomenon and the safe and efficient utilization of direct solar radiation in simple biophysiological models. The effects of spectral absorptance on the photon and irradiance absorption processes are evaluated using the spectra of direct and diffuse solar radiation. The radiation absorption of a leaf arises as a consequence of the absorption of chloroplasts. The photon absorption of chloroplasts is strongly dependent on the distribution of pigment concentrations and their absorbance spectra. While chloroplast movements in response to light are important mechanisms controlling PAR absorption, they are not effective for green light because chloroplasts have the lowest spectral absorptance in the waveband. With the development of palisade tissue, the incident photons per total palisade cell surface area and the absorbed photons per chloroplast decrease. The spectral absorbance of carotenoids is effective in eliminating shortwave PAR (<520 nm), which contains much of the surplus energy that is not used for photosynthesis and is dissipated as heat. The PAR absorptance of a whole leaf shows no substantial difference based on the spectra of direct or diffuse solar radiation. However, most of the near infrared radiation is unabsorbed and heat stress is greatly reduced. The incident solar radiation is too strong to be utilized for photosynthesis under the current CO 2 concentration in the terrestrial environment. Therefore, the photon absorption of a whole leaf is efficiently regulated by photosynthetic pigments with low spectral absorptance in the highest irradiance waveband and through a combination of pigment density distribution and leaf anatomical structures.
Investigation of the effects of inlet shapes on fan noise radiation
NASA Technical Reports Server (NTRS)
Clark, T. L.; Slotboom, D. R.; Vaidya, P. G.
1981-01-01
The effect of inlet shape on forward radiated fan tone noise directivities was investigated under experimentally simplified zero flow conditions. Simulated fan tone noise was radiated to the far field through various shaped zero flow inlets. Baseline data were collected for the simplest baffled and unbaffled straight pipe inlets. These data compared well with prediction. The more general inlet shapes tested were the conical, circular, and exponential surfaces of revolution and an asymmetric inlet achieved by cutting a straight pipe inlet at an acute angle. Approximate theories were developed for these general shapes and some comparisons with data are presented. The conical and exponential shapes produced directivities that differed considerably from the baseline data while the circular shape produced directivities similar to the baseline data. The asymmetric inlet produced asymmetric directivities with significant reductions over the straight pipe data for some angles.
NASA Astrophysics Data System (ADS)
Chin, M.; Diehl, T. L.; Bian, H.; Yu, H.; Kucsera, T. L.; Wild, M., Sr.; Hakuba, M. Z.; Qian, Y.; Stackhouse, P. W., Jr.; Pinker, R. T.; Zhang, Y.; Kato, S.; Loeb, N. G.; Kinne, S.; Streets, D. G.
2017-12-01
Incoming solar radiation drives the Earth's climate system. Long-term surface observations of the solar radiation reaching the surface (RSFC) have shown decreasing or increasing trends, often referred to as solar "dimming" or "brightening", in many regions of the world in the past several decades. Such long-term variation of RSFC mostly reflects the change of the solar-attenuation components within the atmosphere. Anthropogenic emissions of aerosols and precursor gases have changed significantly in the past decades with 50-80% reduction in North America and Europe but an increase of similar magnitude in East and South Asia since 1980, mirroring the change in RSFC over those regions. This has led to suggestions that aerosols play a critical role in determining RSFC trends. This work is to assess the role of direct radiative effects of aerosols on the solar "dimming" and "brightening" trends with modeling studies. First, we will show the trends of aerosol optical depth (AOD) and aerosol surface concentrations in different regions from 1980 to 2009 with remote sensing and in-situ data as well as model simulations, and attribute those changes to anthropogenic or natural sources. We will then show the trends of RSFC from the model and compare the results with observations from the surface networks and satellite-based products. Furthermore, we will use the GOCART model to attribute the "dimming/ brightening" trends to the changes of aerosols through the direct radiative effects. Finally, we will discuss the way forward to understand the aerosol effects on RSFC (as well as on other climate variables) through aerosol-cloud-radiation interactions.
Mirzabozorg, H.; Hariri-Ardebili, M. A.; Shirkhan, M.; Seyed-Kolbadi, S. M.
2014-01-01
The effect of solar radiation on thermal distribution in thin high arch dams is investigated. The differential equation governing thermal behavior of mass concrete in three-dimensional space is solved applying appropriate boundary conditions. Solar radiation is implemented considering the dam face direction relative to the sun, the slop relative to horizon, the region cloud cover, and the surrounding topography. It has been observed that solar radiation changes the surface temperature drastically and leads to nonuniform temperature distribution. Solar radiation effects should be considered in thermal transient analysis of thin arch dams. PMID:24695817
Mirzabozorg, H; Hariri-Ardebili, M A; Shirkhan, M; Seyed-Kolbadi, S M
2014-01-01
The effect of solar radiation on thermal distribution in thin high arch dams is investigated. The differential equation governing thermal behavior of mass concrete in three-dimensional space is solved applying appropriate boundary conditions. Solar radiation is implemented considering the dam face direction relative to the sun, the slop relative to horizon, the region cloud cover, and the surrounding topography. It has been observed that solar radiation changes the surface temperature drastically and leads to nonuniform temperature distribution. Solar radiation effects should be considered in thermal transient analysis of thin arch dams.
NASA Technical Reports Server (NTRS)
Leibensperger, E. M.; Mickley, L. J.; Jacob, D. J.; Chen, W.-T.; Seinfeld, J. H.; Nenes, A.; Adams, P. J.; Streets, D. G.; Kumar, N.; Rind, D.
2012-01-01
We calculate decadal aerosol direct and indirect (warm cloud) radiative forcings from US anthropogenic sources over the 1950-2050 period. Past and future aerosol distributions are constructed using GEOS-Chem and historical emission inventories and future projections from the IPCC A1B scenario. Aerosol simulations are evaluated with observed spatial distributions and 1980-2010 trends of aerosol concentrations and wet deposition in the contiguous US. Direct and indirect radiative forcing is calculated using the GISS general circulation model and monthly mean aerosol distributions from GEOS-Chem. The radiative forcing from US anthropogenic aerosols is strongly localized over the eastern US. We find that its magnitude peaked in 1970-1990, with values over the eastern US (east of 100 deg W) of -2.0Wm(exp-2 for direct forcing including contributions from sulfate (-2.0Wm-2), nitrate (-0.2Wm(exp-2), organic carbon (-0.2Wm(exp-2), and black carbon (+0.4Wm(exp-2). The uncertainties in radiative forcing due to aerosol radiative properties are estimated to be about 50 %. The aerosol indirect effect is estimated to be of comparable magnitude to the direct forcing. We find that the magnitude of the forcing declined sharply from 1990 to 2010 (by 0.8Wm(exp-2) direct and 1.0Wm(exp-2 indirect), mainly reflecting decreases in SO2 emissions, and project that it will continue declining post-2010 but at a much slower rate since US SO2 emissions have already declined by almost 60% from their peak. This suggests that much of the warming effect of reducing US anthropogenic aerosol sources has already been realized. The small positive radiative forcing from US BC emissions (+0.3Wm(exp-2 over the eastern US in 2010; 5% of the global forcing from anthropogenic BC emissions worldwide) suggests that a US emission control strategy focused on BC would have only limited climate benefit.
Bajinskis, Ainars; Natarajan, Adayapalam T; Erixon, Klaus; Harms-Ringdahl, Mats
2013-08-30
The aim of this study was to investigate the relative involvement of three major DNA repair pathways, i.e., non-homologous end joining (NHEJ), homologous recombination (HRR) and base excision (BER) in repair of DNA lesions of different complexity induced by low- or high-LET radiation with emphasis on the contribution of the indirect effect of radiation for these radiation qualities. A panel of DNA repair-deficient CHO cell lines was irradiated by (137)Cs γ-rays or radon progeny α-particles. Irradiation was also performed in the presence of 2M DMSO to reduce the indirect effect of radiation and the complexity of the DNA damage formed. Clonogenic survival and micronucleus assays were used to estimate efficiencies of the different repair pathways for DNA damages produced by direct and indirect effects. Removal of the indirect effect of low-LET radiation by DMSO increased clonogenic survival and decreased MN formation for all cell lines investigated. A direct contribution of the indirect effect of radiation to DNA base damage was suggested by the significant protection by DMSO seen for the BER deficient cell line. Lesions formed by the indirect effect are more readily repaired by the NHEJ pathway than by HRR after irradiation with γ-rays or α-particles as evaluated by cell survival and the yields of MN. The results obtained with BER- and NHEJ-deficient cells suggest that the indirect effect of radiation contributes significantly to the formation of repair substrates for these pathways. Copyright © 2013 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Toll, V.; Männik, A.
2015-03-01
On August 8, 2010, a severe derecho type thunderstorm in the Baltic Sea region coincided with smoke from wildfires in Russia. Remarkable smoke aerosol concentrations, with a maximum aerosol optical depth of more than 2 at 550 nm, were observed near the thunderstorm. The impact of the wildfire smoke on the thunderstorm through direct radiative effects was investigated using the Hirlam Aladin Research for Mesoscale Operational Numerical Weather Prediction in Euromed (HARMONIE) model. HARMONIE was successfully able to resolve the dynamics of the thunderstorm, and simulations that considered the influence of the smoke-related aerosols were compared to simulation without aerosols. As simulated by the HARMONIE model, the smoke reduced the shortwave radiation flux at the surface by as much as 300 W/m2 and decreased the near-surface temperature by as much as 3 °C in the vicinity of the thunderstorm and respectively 100 W/m2 and 1 °C in the thunderstorm region. Atmospheric instability decreased through the direct radiative effect of aerosols, and several dynamic features of the simulated thunderstorm appeared slightly weaker.
Aerosol Radiative Effects on Deep Convective Clouds and Associated Radiative Forcing
NASA Technical Reports Server (NTRS)
Fan, J.; Zhang, R.; Tao, W.-K.; Mohr, I.
2007-01-01
The aerosol radiative effects (ARE) on the deep convective clouds are investigated by using a spectral-bin cloud-resolving model (CRM) coupled with a radiation scheme and an explicit land surface model. The sensitivity of cloud properties and the associated radiative forcing to aerosol single-scattering albedo (SSA) are examined. The ARE on cloud properties is pronounced for mid-visible SSA of 0.85. Relative to the case excluding the ARE, cloud fraction and optical depth decrease by about 18% and 20%, respectively. Cloud droplet and ice particle number concentrations, liquid water path (LWP), ice water path (IWP), and droplet size decrease significantly when the ARE is introduced. The ARE causes a surface cooling of about 0.35 K and significantly high heating rates in the lower troposphere (about 0.6K/day higher at 2 km), both of which lead to a more stable atmosphere and hence weaker convection. The weaker convection and the more desiccation of cloud layers explain the less cloudiness, lower cloud optical depth, LWP and IWP, smaller droplet size, and less precipitation. The daytime-mean direct forcing induced by black carbon is about 2.2 W/sq m at the top of atmosphere (TOA) and -17.4 W/sq m at the surface for SSA of 0.85. The semi-direct forcing is positive, about 10 and 11.2 W/sq m at the TOA and surface, respectively. Both the TOA and surface total radiative forcing values are strongly negative for the deep convective clouds, attributed mostly to aerosol indirect forcing. Aerosol direct and semi-direct effects are very sensitive to SSA. Because the positive semi-direct forcing compensates the negative direct forcing at the surface, the surface temperature and heat fluxes decrease less significantly with the increase of aerosol absorption (decreasing SSA). The cloud fraction, optical depth, convective strength, and precipitation decrease with the increase of absorption, resulting from a more stable and dryer atmosphere due to enhanced surface cooling and atmospheric heating.
DOE Office of Scientific and Technical Information (OSTI.GOV)
C Flynn; AS Koontz; JH Mather
The uncertainties in current estimates of anthropogenic radiative forcing are dominated by the effects of aerosols, both in relation to the direct absorption and scattering of radiation by aerosols and also with respect to aerosol-related changes in cloud formation, longevity, and microphysics (See Figure 1; Intergovernmental Panel on Climate Change, Assessment Report 4, 2008). Moreover, the Arctic region in particular is especially sensitive to changes in climate with the magnitude of temperature changes (both observed and predicted) being several times larger than global averages (Kaufman et al. 2009). Recent studies confirm that aerosol-cloud interactions in the arctic generate climatologically significantmore » radiative effects equivalent in magnitude to that of green house gases (Lubin and Vogelmann 2006, 2007). The aerosol optical depth is the most immediate representation of the aerosol direct effect and is also important for consideration of aerosol-cloud interactions, and thus this quantity is essential for studies of aerosol radiative forcing.« less
Wideł, Maria; Przybyszewski, Waldemar; Rzeszowska-Wolny, Joanna
2009-08-18
It has long been a central radiobiological dogma that the damaging effects of ionizing radiation, such as cell death, cytogenetic changes, apoptosis, mutagenesis, and carcinogenesis, are the results of the direct ionization of cell structures, particularly DNA, or indirect damage via water radiolysis products. However, several years ago attention turned to a third mechanism of radiation, termed the "bystander effect" or "radiation-induced bystander effect" (RIBE). This is induced by agents and signals emitted by directly irradiated cells and manifests as a lowering of survival, cytogenetic damage, apoptosis enhancement, and biochemical changes in neighboring non-irradiated cells. The bystander effect is mainly observed in in vitro experiments using very low doses of alpha particles (range; mGy, cGy), but also after conventional irradiation (X-rays, gamma rays) at low as well as conventional doses. The mechanisms responsible for the bystander effect are complex and still poorly understood. It is believed that molecular signals released from irradiated cells induce different signaling ways in non-irradiated neighboring cells, leading to the observed events. The molecular signals may be transmitted through gap junction intercellular communication and through a medium transfer mechanism. The nature of these transmitted factors are diverse, and still not definitely established. It seems that RIBE may have important clinical implications for health risk associated with radiation exposure. Potentially, this effect may have important implications in the creation of whole-body or localized side effects in tissues beyond the irradiation field and also in low-dose radiological and radioisotope diagnostics. Factors emitted by irradiated cells may result in the risk of genetic instability, mutations, and second primary cancer induction. They might also have their own part in inducing and extending post-radiation side effects in normal tissue. The bystander effect may be a potentially harmful or a useful event in radiotherapy. The elevation of damage to tumor cells not directly hit by radiation or the initiation of tumor cell differentiation may increase the therapeutic ratio. If, however, molecular species secreted by irradiated tumor cells in vivo damage neighboring normal cells (epithelial and endothelial cells, fibroblasts, or lymphocytes), the bystander effect would be harmful and could lead to increased side effects in normal tissue. This is especially important in modern radiotherapy, as 3D conformal radiation therapy (3D-CRT) and intensity-modulated radiation therapy (IMRT) are aimed at diminishing the radiation dose in normal tissues. Recent in vivo studies on animals indicate that bystander effects may appear in organs and tissues remote from the irradiated field and the extension of tissue damage seems to be tissue-type dependent. However, recent experimental results indicate that non-irradiated cells that are neighbors of irradiated cells may diminish radiation damage in the radiation-focused cells. Less is known about the bystander effect during fractionated irradiation. Thus the clinical implications of the bystander effect and its possible modification for radiotherapeutic usefulness is still under debate.
... Radiation (also called x-rays, gamma rays, or photons) either kills tumor cells directly or interferes with ... treatment per day, five days a week, for two to seven weeks. Potiential Side Effects Most people ...
Impact of anthropogenic aerosols on regional climate change in Beijing, China
NASA Astrophysics Data System (ADS)
Zhao, B.; Liou, K. N.; He, C.; Lee, W. L.; Gu, Y.; Li, Q.; Leung, L. R.
2015-12-01
Anthropogenic aerosols affect regional climate significantly through radiative (direct and semi-direct) and indirect effects, but the magnitude of these effects over megacities are subject to large uncertainty. In this study, we evaluated the effects of anthropogenic aerosols on regional climate change in Beijing, China using the online-coupled Weather Research and Forecasting/Chemistry Model (WRF/Chem) with the Fu-Liou-Gu radiation scheme and a spatial resolution of 4km. We further updated this radiation scheme with a geometric-optics surface-wave (GOS) approach for the computation of light absorption and scattering by black carbon (BC) particles in which aggregation shape and internal mixing properties are accounted for. In addition, we incorporated in WRF/Chem a 3D radiative transfer parameterization in conjunction with high-resolution digital data for city buildings and landscape to improve the simulation of boundary-layer, surface solar fluxes and associated sensible/latent heat fluxes. Preliminary simulated meteorological parameters, fine particles (PM2.5) and their chemical components agree well with observational data in terms of both magnitude and spatio-temporal variations. The effects of anthropogenic aerosols, including BC, on radiative forcing, surface temperature, wind speed, humidity, cloud water path, and precipitation are quantified on the basis of simulation results. With several preliminary sensitivity runs, we found that meteorological parameters and aerosol radiative effects simulated with the incorporation of improved BC absorption and 3-D radiation parameterizations deviate substantially from simulation results using the conventional homogeneous/core-shell configuration for BC and the plane-parallel model for radiative transfer. Understanding of the aerosol effects on regional climate change over megacities must consider the complex shape and mixing state of aerosol aggregates and 3D radiative transfer effects over city landscape.
Jeans instability of rotating magnetized quantum plasma: Influence of radiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Joshi, H., E-mail: hjoshi8525@yahoo.com; Pensia, R. K.
2015-07-31
The effect of radiative heat-loss function and rotation on the Jeans instability of quantum plasma is investigated. The basic set of equations for this problem is constructed by considering quantum magnetohydrodynamic (QMHD) model. Using normal mode analysis, the general dispersion relation is obtained. This dispersion relation is studied in both, longitudinal and transverse direction of propagations. In both case of longitudinal and transverse direction of propagation, the Jeans instability criterion is modified due to presence of radiative heat-loss function and quantum correction.
NASA Astrophysics Data System (ADS)
Wang, S.; Gautam, R.; Lau, W. K.; Tsay, S.; Sun, W.; Kim, K.; Chern, J.; Colarco, P. R.; Hsu, N. C.; Lin, N.
2011-12-01
Current assessment of aerosol radiative effect is hindered by our incomplete knowledge of aerosol optical properties, especially absorption, and our current inability to quantify physical and microphysical processes. In this research, we investigate direct aerosol radiative effect over heavy aerosol loading areas (e.g., Indo-Gangetic Plains, South/East Asia) and its feedbacks on the South Asian climate during the pre-monsoon season (March-June) using the Purdue Regional Climate Model (PRCM) with prescribed aerosol data derived by the NASA Goddard Earth Observing System Model (GEOS-5). Our modeling domain covers South and East Asia (60-140E and 0-50N) with spatial resolutions of 45 km in horizontal and 28 layers in vertical. The model is integrated from 15 February to 30 June 2008 continuously without nudging (i.e., only forced by initial/boundary conditions). Two numerical experiments are conducted with and without the aerosol-radiation effects. Both simulations are successful in reproducing the synoptic patterns on seasonal-to-interannual time scales and capturing a pre-monsoon feature of the northward rainfall propagation over Indian region in early June which shown in Tropical Rainfall Measuring Mission (TRMM) observation. Preliminary result suggests aerosol-radiation interactions mainly alter surface-atmosphere energetics and further result in an adjustment of the vertical temperature distribution in lower atmosphere (below 700 hPa). The modifications of temperature and associated rainfall and circulation feedbacks on the regional climate will be discussed in the presentation. In addition to modeling study, we will also present the most recent results on aerosol properties, regional aerosol absorption, and radiative forcing estimation based on NASA's operational satellite and ground-based remote sensing. Observational results show spatial gradients in aerosol loading and solar absorption accounting over Indo-Gangetic Plains during the pre-monsoon season. The direct radiative forcing of aerosols at surface to be -19-23 Wm-2 (12-15 % of the surface solar insolation) over NW India is estimated using an observational approach. A comparison of aerosol radiative forcing between numerical simulation and observational estimate will be presented. Overall, this work will demonstrate the aerosol direct effects from both modeling and observation perspectives, and further to assess the physical processes underlying the aerosol radiative feedbacks and possible impacts on the large-scale South Asian monsoon system.
Zecchin, Massimo; Morea, Gaetano; Severgnini, Mara; Sergi, Elisabetta; Baratto Roldan, Anna; Bianco, Elisabetta; Magnani, Silvia; De Luca, Antonio; Zorzin Fantasia, Anna; Salvatore, Luca; Milan, Vittorino; Giannini, Gianrossano; Sinagra, Gianfranco
2016-02-01
Malfunctions of cardiac implantable electronical devices (CIED) have been described after high-energy radiation therapy even in the absence of direct exposure to ionizing radiation, due to diffusion of neutrons (n) causing soft errors in inner circuits. The purpose of the study was to analyse the effect of scattered radiation on different types and models of CIED and the possible sources of malfunctions. Fifty-nine explanted CIED were placed on an anthropomorphous phantom of tissue-equivalent material, and a high-energy photon (15 MV) radiotherapy course (total dose = 70 Gy) for prostate treatment was performed. All devices were interrogated before and after radiation. Radiation dose, the electromagnetic field, and neutron fluence at the CIED site were measured. Thirty-four pacemakers (PM) and 25 implantable cardioverter-defibrillators (ICD) were analysed. No malfunctions were detected before radiation. After radiation a software malfunction was evident in 13 (52%) ICD and 6 (18%) PM; no significant electromagnetic field or photon radiations were detected in the thoracic region. Neutron capture was demonstrated by the presence of the (198)Au((197)Au + n) or (192)Ir((191)Ir + n) isotope activation; it was significantly greater in ICD than in PM and non-significantly greater in damaged devices. A greater effect in St Jude PM (2/2 damaged), Boston (9/11), and St Jude ICD (3/6) and in older ICD models was observed; the year of production was not relevant in PM. High-energy radiation can cause different malfunctions on CIED, particularly ICD, even without direct exposure to ionizing radiation due to scattered radiation of neutrons produced by the linear accelerator. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com.
NASA Astrophysics Data System (ADS)
Mathur, R.; Pleim, J.; Wong, D.; Hogrefe, C.; Xing, J.; Wei, C.; Gan, M.
2013-12-01
While aerosol radiative effects have been recognized as some of the largest sources of uncertainty among the forcers of climate change, the verification of the spatial and temporal variability of the magnitude and directionality of aerosol radiative forcing has remained challenging. A detailed investigation of the processes regulating aerosol distributions, their optical properties, and their radiative effects and verification of their simulated effects for past conditions relative to measurements is needed in order to build confidence in the estimates of the projected impacts arising from changes in both anthropogenic forcing and climate change. Anthropogenic emissions of primary aerosol and gaseous precursors have witnessed dramatic changes over the past two decades across the northern hemisphere. During the period 1990-2010, SO2 and NOx emissions across the US have reduced by about 66% and 50%, respectively, mainly due to Title IV of the U.S. Clean Air Act Amendments (CAA). In contrast, anthropogenic emissions have increased dramatically in many developing regions during this period. We conduct a systematic investigation of changes in anthropogenic emissions of primary aerosols and gaseous precursors over the past two decades, their impacts on trends and spatial heterogeneity in anthropogenic aerosol loading across the northern hemisphere troposphere, and subsequent impacts on regional radiation budgets. The coupled WRF-CMAQ model is applied for selected time periods spanning the period 1990-2010 over a domain covering the northern hemisphere and a nested finer resolution continental U.S. domain. The model includes detailed treatment of direct effects of aerosols on photolysis rates as well as on shortwave radiation. Additionally, treatment of aerosol indirect effects on clouds has also recently been implemented. A methodology is developed to consistently estimate U.S. emission inventories for the 20-year period accounting for air quality regulations as well as population trends, economic conditions, and technology changes in motor vehicles and electric power generation. Analysis of measurements of aerosol composition, radiation, and associated variables, over the past two decades will be presented which indicate significant reductions in the tropospheric aerosol burden as well as an increase in down-welling shortwave radiation at numerous sites across the U.S. Initial applications of the coupled WRF-CMAQ model for time-periods pre and post the implementation of CAA Title IV will be discussed and comparisons with measurements to assess the model's ability to capture trends in aerosol burden, composition, and direct aerosol effects on surface shortwave radiation will be presented.
NASA Astrophysics Data System (ADS)
Park, Shin-Young; Lee, Hyo-Jung; Kang, Jeong-Eon; Lee, Taehyoung; Kim, Cheol-Hee
2018-01-01
The online model, Weather Research and Forecasting Model with Chemistry (WRF-Chem) is employed to interpret the effects of aerosol-cloud-precipitation interaction on mesoscale meteorological fields over Northeast Asia during the Megacity Air Pollution Study-Seoul (MAPS-Seoul) 2015 campaign. The MAPS-Seoul campaign is a pre-campaign of the Korea-United States Air Quality (KORUS-AQ) campaign conducted over the Korean Peninsula. We validated the WRF-Chem simulations during the campaign period, and analyzed aerosol-warm cloud interactions by diagnosing both aerosol direct, indirect, and total effects. The results demonstrated that aerosol directly decreased downward shortwave radiation up to -44% (-282 W m-2) for this period and subsequently increased downward longwave radiation up to +15% (∼52 W m-2) in the presence of low-level clouds along the thematic area. Aerosol increased cloud fraction indirectly up to ∼24% with the increases of both liquid water path and the droplet number mixing ratio. Precipitation properties were altered both directly and indirectly. Direct effects simply changed cloud-precipitation quantities via simple updraft process associated with perturbed radiation and temperature, while indirect effects mainly suppressed precipitation, but sometimes increased precipitation in the higher relative humidity atmosphere or near vapor-saturated condition. The total aerosol effects caused a time lag of the precipitation rate with the delayed onset time of up to 9 h. This implies the importance of aerosol effects in improving mesoscale precipitation rate prediction in the online approach in the presence of non-linear warm cloud.
Computational Modeling of Laser-Cell Biochemical Interactions
2010-12-31
San Antonio, TX 78228 Jeffrey W. Oliver. Ph.D. Human Effectiveness Directorate Directed Energy Bioeffects Division Optical Radiation Branch...Affairs Case No. 11-080 Air Force Research Laboratory 711 Human Performance Wing Human Effectiveness Directorate Directed Energy Bioeffects...Directed Energy Bioeffects Division Human Effectiveness Directorate 711 Human Performance Wing Air Force Research Laboratory This report is
Kovalchuk, Anna; Kolb, Bryan
2017-07-03
Based on the most recent estimates by the Canadian Cancer Society, 2 in 5 Canadians will develop cancer in their lifetimes. More than half of all cancer patients receive some type of radiation therapy, and all patients undergo radiation-based diagnostics. While radiation is one of the most important diagnostic and treatments modalities, high-dose cranial radiation therapy causes numerous central nervous system side-effects, including declines in cognitive function, memory, and attention. While the mechanisms of these effects have been studies, they still need to be further elucidated. On the other hand, the effects of low dose radiation as well as indirect radiation bystander effects on the brain remain elusive. We pioneered analysis of the molecular and cellular effects of low dose direct, bystander and scatter radiation on the brain. Using a rat model, we showed that low dose radiation exposures cause molecular and cellular changes in the brain and impacts animal behavior. Here we reflect upon our recent findings and current state of knowledge in the field, and suggest novel radiation effect biomarkers and means of prevention. We propose strategies and interventions to prevent and mitigate radiation effects on the brain.
Casualty Estimation for Nuclear and Radiological Weapons
2016-06-01
usually defined as energy deposited (joule) per unit of mass (kilogram). See gray and rad. Acute Radiation Syndrome (ARS): ARS is a serious illness...I-2 ARS Acute Radiation Syndrome BSA body surface area CBRN chemical, biological, radiological, and nuclear CONV convalescent CUT cutaneous DOW...include acute effects, which may result from internal or external radiation exposure. The severity of these effects is directly related to the dosage
Regional aerosol radiative and hydrological effects over the mid-Atlantic corridor
NASA Astrophysics Data System (ADS)
Creekmore, Torreon N.
A thorough assessment of direct, indirect, and semi-direct influences of aerosols on Earth's energy budget is required to better understand climate and estimate how it may change in the future. Clear-sky surface broadband (measured and modeled) irradiance, spectral aerosol optical depth, heating rate profiles, and non-radiative flux measurements were conducted at a state-of-the-art site, developed by the NOAA-Howard University Center for Atmospheric Sciences (NCAS) program, providing a best estimate of aerosol radiative atmosphere-surface interactions. Methods developed by the Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Program were applied to: (1) temporally quantify regional aerosol forcing, (2) to derive an empirical equation describing a relationship between aerosol optical depth and normalized diffuse ratio, (3) evaluate aerosol impacts on atmospheric heating, and (4) evaluate how aerosol forcing impacts may possibly reduce latent and sensible fluxes. Measurements were obtained during the period of May--September for the years of 2005, 2006, and 2007. Atmospheric aerosols are among the key uncertainties affecting the Earth's climate and atmospheric radiative processes. Present-day increases in aerosol concentrations directly, indirectly, and semi-directly impact the Earth's energy budget (i.e., cooling the surface and heating the atmosphere), thereby contributing to climate change. The Howard University Beltsville Site (HUBS) has experienced a greater loss in mean normalized aerosol radiative forcing with time, as observations show a decrease from --0.9 in 2005 to --3.1 and --3.4 W/m2 for 2006 and 2007 respectively, in mean net surface irradiance. The mean normalized aerosol radiative forcing estimated for the period considered was --2.5 W/m2. The reduction in surface solar insolation is due to increased scattering and absorption related to increased aerosol burdens v for the period, promoting surface cooling and atmospheric heating. Calculation of radiative flux and heating rates profiles, which are constrained by HUBS observations, were performed by the 1-D Fu-Liou radiative transfer model to investigate the effect of polluted and pristine aerosol conditions on the surface energy budget and hydrological cycle. For HUBS the surface forcing (--14.2 W/m2) and atmospheric forcing (9.9 W/m2) were significantly larger than the TOA (--4.3 W/m2) radiative forcing. Associated aerosol heating, as well as reduced surface insolation, may lead to increasing near surface static stability, and reduced vertical transport of moisture into the atmospheric boundary layer, and over time, a possible spin-down of the hydrological cycle. It is shown that HUBS provides an ideal opportunity for improving measurements and datasets, thus allowing for both the study and understanding of aerosol impacts on the climate system. Further, results show that in order to provide reference quality data and constrain aerosol radiative effects over land, ground-based research sites must conform to HUBS standards of: (1) instrumentation (e.g. passive and active sensors); (2) operational protocols (e.g. calibration and routine cleaning); (3) rigorous cloud screening protocols; and (4) incorporation of ARM QC and modified FFA algorithms. HUBS surface measurements provides the reference quality data necessary and capability required to help enhance measurements and constrain current uncertainties in estimates of aerosol direct effects over land. Incorporating a combined technique of both active and passive instruments reduced the direct radiative forcing estimates by ˜82 W/m2. The analysis of aerosol effects over HUBS helps continue in bridging the gap of applying measurements for improvement of climate simulations by generating observational products, which describes aerosol and radiation field characteristics in detail.
Radiation protection for manned space activities
NASA Technical Reports Server (NTRS)
Jordan, T. M.
1983-01-01
The Earth's natural radiation environment poses a hazard to manned space activities directly through biological effects and indirectly through effects on materials and electronics. The following standard practices are indicated that address: (1) environment models for all radiation species including uncertainties and temporal variations; (2) upper bound and nominal quality factors for biological radiation effects that include dose, dose rate, critical organ, and linear energy transfer variations; (3) particle transport and shielding methodology including system and man modeling and uncertainty analysis; (4) mission planning that includes active dosimetry, minimizes exposure during extravehicular activities, subjects every mission to a radiation review, and specifies operational procedures for forecasting, recognizing, and dealing with large solar flaes.
NASA Astrophysics Data System (ADS)
Lolli, Simone; Madonna, Fabio; Rosoldi, Marco; Campbell, James R.; Welton, Ellsworth J.; Lewis, Jasper R.; Gu, Yu; Pappalardo, Gelsomina
2018-03-01
In the past 2 decades, ground-based lidar networks have drastically increased in scope and relevance, thanks primarily to the advent of lidar observations from space and their need for validation. Lidar observations of aerosol and cloud geometrical, optical and microphysical atmospheric properties are subsequently used to evaluate their direct radiative effects on climate. However, the retrievals are strongly dependent on the lidar instrument measurement technique and subsequent data processing methodologies. In this paper, we evaluate the discrepancies between the use of Raman and elastic lidar measurement techniques and corresponding data processing methods for two aerosol layers in the free troposphere and for two cirrus clouds with different optical depths. Results show that the different lidar techniques are responsible for discrepancies in the model-derived direct radiative effects for biomass burning (0.05 W m-2 at surface and 0.007 W m-2 at top of the atmosphere) and dust aerosol layers (0.7 W m-2 at surface and 0.85 W m-2 at top of the atmosphere). Data processing is further responsible for discrepancies in both thin (0.55 W m-2 at surface and 2.7 W m-2 at top of the atmosphere) and opaque (7.7 W m-2 at surface and 11.8 W m-2 at top of the atmosphere) cirrus clouds. Direct radiative effect discrepancies can be attributed to the larger variability of the lidar ratio for aerosols (20-150 sr) than for clouds (20-35 sr). For this reason, the influence of the applied lidar technique plays a more fundamental role in aerosol monitoring because the lidar ratio must be retrieved with relatively high accuracy. In contrast, for cirrus clouds, with the lidar ratio being much less variable, the data processing is critical because smoothing it modifies the aerosol and cloud vertically resolved extinction profile that is used as input to compute direct radiative effect calculations.
Directional radiation detectors
Dowell, Jonathan L.
2017-09-12
Directional radiation detectors and systems, methods, and computer-readable media for using directional radiation detectors to locate a radiation source are provided herein. A directional radiation detector includes a radiation sensor. A radiation attenuator partially surrounds the radiation sensor and defines an aperture through which incident radiation is received by the radiation sensor. The aperture is positioned such that when incident radiation is received directly through the aperture and by the radiation sensor, a source of the incident radiation is located within a solid angle defined by the aperture. The radiation sensor senses at least one of alpha particles, beta particles, gamma particles, or neutrons.
On the role of the radiation directivity in noise reduction for STOL aircraft.
NASA Technical Reports Server (NTRS)
Gruschka, H. D.
1972-01-01
The radiation characteristics of distributed randomly fluctuating acoustic sources when shielded by finite surfaces are discussed briefly. A number of model tests using loudspeakers as artificial noise sources with a given broadband power density spectrum are used to demonstrate the effectiveness of reducing the radiated noise intensity in certain directions due to shielding. In the lateral direction of the source array noise reductions of 12 dB are observed with relatively small shields. The same shields reduce the backward radiation by approximately 20 dB. With the results obtained in these acoustic model tests the potentials of jet noise reduction of jet flap propulsion systems applicable in future STOL aircraft are discussed. The jet flap configuration as a complex aerodynamic noise source is described briefly.
Tomita, Masanori; Maeda, Munetoshi
2015-01-01
Abstract Elucidating the biological effect of low linear energy transfer (LET), low-dose and/or low-dose-rate ionizing radiation is essential in ensuring radiation safety. Over the past two decades, non-targeted effects, which are not only a direct consequence of radiation-induced initial lesions produced in cellular DNA but also of intra- and inter-cellular communications involving both targeted and non-targeted cells, have been reported and are currently defining a new paradigm in radiation biology. These effects include radiation-induced adaptive response, low-dose hypersensitivity, genomic instability, and radiation-induced bystander response (RIBR). RIBR is generally defined as a cellular response that is induced in non-irradiated cells that receive bystander signals from directly irradiated cells. RIBR could thus play an important biological role in low-dose irradiation conditions. However, this suggestion was mainly based on findings obtained using high-LET charged-particle radiations. The human population (especially the Japanese, who are exposed to lower doses of radon than the world average) is more frequently exposed to low-LET photons (X-rays or γ-rays) than to high-LET charged-particle radiation on a daily basis. There are currently a growing number of reports describing a distinguishing feature between photon-induced bystander response and high-LET RIBR. In particular, photon-induced bystander response is strongly influenced by irradiation dose, the irradiated region of the targeted cells, and p53 status. The present review focuses on the photon-induced bystander response, and discusses its impact on the low-dose radiation effect. PMID:25361549
Hahn, Peter J; Lai, Zhi-Wei; Nevaldine, Barbara; Schiff, Ninel; Fiore, Nancy C; Silverstone, Allen E
2003-11-01
We have quantified the emergence of early chromatin breaks during the signal transduction phase of apoptosis in mouse thymocytes after treatment with either ionizing radiation or dexamethasone. Dexamethasone at 1 microM can induce significant levels of DNA breaks (equivalent to the amount induced directly by 7.5 Gy ionizing radiation) within 0.5 h of treatment. The execution phase of apoptosis was not observed until 4-6 h after the same treatment. The presence of the Bcl2 transgene under the control of the p56lck promoter almost completely inhibited apoptosis up to 24 h after treatment, but it had virtually no effect on the early chromatin cleavage occurring in the first 6 h. Ionizing radiation induced chromatin cleavage both directly by damaging DNA and indirectly with kinetics similar to the induction of chromatin cleavage by dexamethasone. The presence of the Bcl2 transgene had no effect on the direct or indirect radiation-induced cleavage in the first 6 h, but after the first 6 h, the Bcl2 gene inhibited further radiation-induced chromatin cleavage. These results suggest that endonucleases are activated within minutes of treatment with either dexamethasone or ionizing radiation as part of the very early signal transduction phase of apoptosis, and prior to the irreversible commitment to cell death.
Physics of Acoustic Radiation from Jet Engine Inlets
NASA Technical Reports Server (NTRS)
Tam, Christopher K. W.; Parrish, Sarah A.; Envia, Edmane; Chien, Eugene W.
2012-01-01
Numerical simulations of acoustic radiation from a jet engine inlet are performed using advanced computational aeroacoustics (CAA) algorithms and high-quality numerical boundary treatments. As a model of modern commercial jet engine inlets, the inlet geometry of the NASA Source Diagnostic Test (SDT) is used. Fan noise consists of tones and broadband sound. This investigation considers the radiation of tones associated with upstream propagating duct modes. The primary objective is to identify the dominant physical processes that determine the directivity of the radiated sound. Two such processes have been identified. They are acoustic diffraction and refraction. Diffraction is the natural tendency for an acoustic wave to follow a curved solid surface as it propagates. Refraction is the turning of the direction of propagation of sound waves by mean flow gradients. Parametric studies on the changes in the directivity of radiated sound due to variations in forward flight Mach number and duct mode frequency, azimuthal mode number, and radial mode number are carried out. It is found there is a significant difference in directivity for the radiation of the same duct mode from an engine inlet when operating in static condition and in forward flight. It will be shown that the large change in directivity is the result of the combined effects of diffraction and refraction.
Direct Computation of Sound Radiation by Jet Flow Using Large-scale Equations
NASA Technical Reports Server (NTRS)
Mankbadi, R. R.; Shih, S. H.; Hixon, D. R.; Povinelli, L. A.
1995-01-01
Jet noise is directly predicted using large-scale equations. The computational domain is extended in order to directly capture the radiated field. As in conventional large-eddy-simulations, the effect of the unresolved scales on the resolved ones is accounted for. Special attention is given to boundary treatment to avoid spurious modes that can render the computed fluctuations totally unacceptable. Results are presented for a supersonic jet at Mach number 2.1.
Wake Geometry Effects on Rotor Blade-Vortex Interaction Noise Directivity
NASA Technical Reports Server (NTRS)
Martin, R. M.; Marcolini, Michael A.; Splettstoesser, W. R.; Schultz, K.-J.
1990-01-01
Acoustic measurements from a model rotor wind tunnel test are presented which show that the directionality of rotor blade vortex interaction (BVI) noise is strongly dependent on the rotor advance ratio and disk attitude. A rotor free wake analysis is used to show that the general locus of interactions on the rotor disk is also strongly dependent on advance ratio and disk attitude. A comparison of the changing directionality of the BVI noise with changes in the interaction locations shows that the strongest noise radiation occurs in the direction of motion normal to the blade span at the time of interaction, for both advancing and retreating side BVI. For advancing side interactions, the BVI radiation angle down from the tip-path plane appears relatively insensitive to rotor operating condition and is typically between 40 and 55 deg below the disk. However, the azimuthal radiation direction shows a clear trend with descent speed, moving towards the right of the flight path with increasing descent speed. The movement of the strongest radiation direction is attributed to the movement of the interaction locations on the rotor disk with increasing descent speed.
Direct Aerosol Radiative Forcing: Calculations and Measurements from the Tropospheric
NASA Technical Reports Server (NTRS)
Russell, P. B.; Hignett, P.; Stowe, L. L.; Livingston, J. M.; Kinne, S.; Wong, J.; Chan, K. Roland (Technical Monitor)
1997-01-01
Radiative forcing is defined as the change in the net (downwelling minus upwelling) radiative flux at a given level in the atmosphere. This net flux is the radiative power density available to drive climatic processes in the earth-atmosphere system below that level. Recent research shows that radiative forcing by aerosol particles is a major source of uncertainty in climate predictions. To reduce those uncertainties, TARFOX was designed to determine direct (cloud-free) radiative forcing by the aerosols in one of the world's major industrial pollution plumes--that flowing from the east coast of the US over the Atlantic Ocean. TARFOX measured a variety of aerosol radiative effects (including direct forcing) while simultaneously measuring the chemical, physical, and optical properties of the aerosol particles causing those effects. The resulting data sets permit a wide variety of tests of the consistency, or closure, among the measurements and the models that link them. Because climate predictions use the same or similar model components, closure tests help to assess and reduce prediction uncertainties. In this work we use the TARFOX-determined aerosol, gas, and surface properties to compute radiative forcing for a variety of aerosol episodes, with inadvisable optical depths ranging from 0.07 to 0.6. We calculate forcing by several techniques with varying degrees of sophistication, in part to test the range of applicability of simplified techniques--which are often the only ones feasible in climate predictions by general circulation models (GCMs). We then compare computed forcing to that determined from: (1) Upwelling and downwelling fluxes (0.3-0.7 mm and 0.7-3.0 mm) measured by radiometers on the UK MRF C-130. and (2) Daily average cloud-free absorbed solar and emitted thermal radiative flux at the top of the atmosphere derived from the AVHRR radiometer on the NOAA- 14 satellite. The calculations and measurements all yield aerosol direct radiative forcing in the range -50 to -190 W sq m per unit inadvisable optical depth. The magnitudes are about 15 to 100 times larger than the global-average direct forcing expected for the global-average sulfate aerosol optical depth of 0.04. The reasons for the larger forcing in TARFOX include the relatively large optical depths and the focus on cloud-free, daytime conditions over the dark ocean surface. These are the conditions that produce the actual major radiative forcing events that contribute to any global-average climate effect. Detailed comparisons of calculated and measured forcings for specific events are used for more refined tests of closure.
NASA Astrophysics Data System (ADS)
Jimenez-Guerrero, Pedro; Balzarini, Alessandra; Baró, Rocío; Curci, Gabriele; Forkel, Renate; Hirtl, Marcus; Honzak, Luka; Langer, Matthias; Pérez, Juan L.; Pirovano, Guido; San José, Roberto; Tuccella, Paolo; Werhahn, Johannes; Zabkar, Rahela
2014-05-01
The study of the response of the aerosol levels in the atmosphere to a changing climate and how this affects the radiative budget of the Earth (direct, semi-direct and indirect effects) is an essential topic to build confidence on climate science, since these feedbacks involve the largest uncertainties nowadays. Air quality-climate interactions (AQCI) are, therefore, a key, but uncertain contributor to the anthropogenic forcing that remains poorly understood. To build confidence in the AQCI studies, regional-scale integrated meteorology-atmospheric chemistry models (i.e., models with on-line chemistry) that include detailed treatment of aerosol life cycle and aerosol impacts on radiation (direct effects) and clouds (indirect effects) are in demand. In this context, the main objective of this contribution is the study and definition of the uncertainties in the climate-chemistry-aerosol-cloud-radiation system associated to the direct radiative forcing and the indirect effect caused by aerosols over Europe, using an ensemble of fully-coupled meteorology-chemistry model simulations with the WRF-Chem model run under the umbrella of AQMEII-Phase 2 international initiative. Simulations were performed for Europe for the entire year 2010. According to the common simulation strategy, the year was simulated as a sequence of 2-day time slices. For better comparability, the seven groups applied the same grid spacing of 23 km and shared common processing of initial and boundary conditions as well as anthropogenic and fire emissions. With exception of a simulation with different cloud microphysics, identical physics options were chosen while the chemistry options were varied. Two model set-ups will be considered here: one sub-ensemble of simulations not taking into account any aerosol feedbacks (the baseline case) and another sub-ensemble of simulations which differs from the former by the inclusion of aerosol-radiation feedback. The existing differences for meteorological variables (mainly 2-m temperature and precipitation) and air quality levels (mainly ozone an PM10) between both sub-ensembles of WRF-Chem simulations have been characterized. In the case of ozone and PM10, an increase in solar radiation and temperature has generally resulted in an enhanced photochemical activity and therefore a negative feedback (areas with low aerosol concentrations present more than 50 W m-2 higher global radiation for cloudy conditions). However, simulated feedback effects between aerosol concentrations and meteorological variables and on pollutant distributions strongly depend on the model configuration and the meteorological situation. These results will help providing improved science-based foundations to better assess the impacts of climate variability, support the development of effective climate change policies and optimize private decision-making.
Schilling-Tóth, Boglárka; Sándor, Nikolett; Kis, Eniko; Kadhim, Munira; Sáfrány, Géza; Hegyesi, Hargita
2011-11-01
One of the key issues of current radiation research is the biological effect of low doses. Unfortunately, low dose science is hampered by the unavailability of easily performable, reliable and sensitive quantitative biomarkers suitable detecting low frequency alterations in irradiated cells. We applied a quantitative real time polymerase chain reaction (qRT-PCR) based protocol detecting common deletions (CD) in the mitochondrial genome to assess direct and non-targeted effects of radiation in human fibroblasts. In directly irradiated (IR) cells CD increased with dose and was higher in radiosensitive cells. Investigating conditioned medium-mediated bystander effects we demonstrated that low and high (0.1 and 2Gy) doses induced similar levels of bystander responses and found individual differences in human fibroblasts. The bystander response was not related to the radiosensitivity of the cells. The importance of signal sending donor and signal receiving target cells was investigated by placing conditioned medium from a bystander response positive cell line (F11-hTERT) to bystander negative cells (S1-hTERT) and vice versa. The data indicated that signal sending cells are more important in the medium-mediated bystander effect than recipients. Finally, we followed long term effects in immortalized radiation sensitive (S1-hTERT) and normal (F11-hTERT) fibroblasts up to 63 days after IR. In F11-hTERT cells CD level was increased until 35 days after IR then reduced back to control level by day 49. In S1-hTERT cells the increased CD level was also normalized by day 42, however a second wave of increased CD incidence appeared by day 49 which was maintained up to day 63 after IR. This second CD wave might be the indication of radiation-induced instability in the mitochondrial genome of S1-hTERT cells. The data demonstrated that measuring CD in mtDNA by qRT-PCR is a reliable and sensitive biomarker to estimate radiation-induced direct and non-targeted effects. Copyright © 2011 Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Hill, D. J. T.; O'Donnell, J. H.
1981-01-01
Describes an interdisciplinary student experiment based upon the radiation effects on polymers, integrating some of the fundamentals of radiation chemistry, polymer chemistry, and material science. Also demonstrates how the information gained in the experiment has direct commercial application in product manufacture or processing. (CS)
Radiation model predictions and validation using LDEF satellite data
NASA Technical Reports Server (NTRS)
Armstrong, T. W.; Colborn, B. L.
1993-01-01
Predictions and comparisons with the radiation dose measurements on Long Duration Exposure Facility (LDEF) by thermoluminescent dosimeters were made to evaluate the accuracy of models currently used in defining the ionizing radiation environment for low Earth orbit missions. The calculations include a detailed simulation of the radiation exposure (altitude and solar cycle variations, directional dependence) and shielding effects (three-dimensional LDEF geometry model) so that differences in the predicted and observed doses can be attributed to environment model uncertainties. The LDEF dose data are utilized to assess the accuracy of models describing the trapped proton flux, the trapped proton directionality, and the trapped electron flux.
Shim, Grace; Ricoul, Michelle; Hempel, William M.; Azzam, Edouard I.; Sabatier, Laure
2014-01-01
It is well established that ionizing radiation induces chromosomal damage, both following direct radiation exposure and via non-targeted (bystander) effects, activating DNA damage repair pathways, of which the proteins are closely linked to telomeric proteins and telomere maintenance. Long-term propagation of this radiation-induced chromosomal damage during cell proliferation results in chromosomal instability. Many studies have shown the link between radiation exposure and radiation-induced changes in oxidative stress and DNA damage repair in both targeted and non-targeted cells. However, the effect of these factors on telomeres, long established as guardians of the genome, still remains to be clarified. In this review, we will focus on what is known about how telomeres are affected by exposure to low- and high-LET ionizing radiation and during proliferation, and will discuss how telomeres may be a key player in the process of radiation-induced carcinogenesis. PMID:24486376
On the scattering directionality of a dielectric particle dimer of High Refractive Index.
Barreda, Ángela I; Saleh, Hassan; Litman, Amélie; González, Francisco; Geffrin, Jean-Michel; Moreno, Fernando
2018-05-22
Low-losses and directionality effects exhibited by High Refractive Index Dielectric particles make them attractive for applications where radiation direction control is relevant. For instance, isolated metallo-dielectric core-shell particles or aggregates (dimers) of High Refractive Index Dielectric particles have been proposed for building operational switching devices. Also, the possibility of using isolated High Refractive Index Dielectric particles for optimizing solar cells performance has been explored. Here, we present experimental evidence in the microwave range, that a High Refractive Index Dielectric dimer of spherical particles is more efficient for redirecting the incident radiation in the forward direction than the isolated case. In fact, we report two spectral regions in the dipolar spectral range where the incident intensity is mostly scattered in the forward direction. They correspond to the Zero-Backward condition (also observed for isolated particles) and to a new condition, denoted as "near Zero-Backward" condition, which comes from the interaction effects between the particles. The proposed configuration has implications in solar energy harvesting devices and in radiation guiding.
Non-gravitational perturbations and satellite geodesy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Milani, A.; Nobill, A.M.; Farinella, P.
1987-01-01
This book presents the basic ideas of the physics of non-gravitational perturbations and the mathematics required to compute their orbital effects. It conveys the relevance of the different problems that must be solved to achieve a given level of accuracy in orbit determination and in recovery of geophysically significant parameters. Selected Contents are: Orders of Magnitude of the Perturbing Forces, Tides and Apparent Forces, Tools from Celestial Mechanics, Solar Radiation Pressure-Direct Effects: Satellite-Solar Radiation Interaction, Long-Term Effects on Semi-Major Axis, Radiation Pressure-Indirect Effects: Earth-Reflected Radiation Pressure, Anisotropic Thermal Emission, Drag: Orbital Perturbations by a Drag-Like Force, and Charged Particle Drag.
Evident Biological Effects of Space Radiation in Astronauts
NASA Technical Reports Server (NTRS)
Wu, Honglu
2004-01-01
Though cancer risks are the primary concern for astronauts exposed to space radiation and a number of astronauts have developed cancer, identifying a direct association or cause of disease has been somewhat problematic due to a lack of statistics and a lack of an appropriate control group. However, several bio,logical effects observed in astronauts are believed to be primarily due to exposure to space radiation. Among those are, light flashes experienced by astronauts from early missions, cataract development in the crewmembers and excess chromosome aberrations detected in astronauts' lymphocytes postmission. The space radiation environment and evident biological effects will be discussed.
Helicity-Driven Ratchet Effect Enhanced by Plasmons
NASA Astrophysics Data System (ADS)
Rozhansky, I. V.; Kachorovskii, V. Yu.; Shur, M. S.
2015-06-01
We demonstrate that the ratchet effect—a radiation-induced direct current in periodically modulated structures with built-in asymmetry—is dramatically enhanced in the vicinity of the plasmonic resonances and has a nontrivial polarization dependence. For a circular polarization, the current component, perpendicular to the modulation direction, changes sign with the inversion of the radiation helicity. In the high-mobility structures, this component might increase by several orders of magnitude due to the plasmonic effects and exceed the current component in the modulation direction. Our theory also predicts that in the dirty systems, where the plasma resonances are suppressed, the ratchet current is controlled by the Maxwell relaxation.
Aerosol direct and indirect radiative effect over Eastern Mediterranean
NASA Astrophysics Data System (ADS)
Georgoulias, Aristeidis; Alexandri, Georgia; Zanis, Prodromos; Ntogras, Christos; Poeschl, Ulrich; Kourtidis, Kostas
In this work, we present results from the QUADIEEMS project which is focused on the aerosol-cloud relations and the aerosol direct and indirect radiative effect over the region of Eastern Mediterranean. First, a gridded dataset at a resolution of 0.1x0.1 degrees (~10km) with aerosol and cloud related parameters was compiled, using level-2 satellite observations from MODIS TERRA (3/2000-12/2012) and AQUA (7/2002-12/2012). The aerosol gridded dataset has been validated against sunphotometric measurements from 12 AERONET ground stations, showing that generally MODIS overestimates aerosol optical depth (AOD550). Then, the AOD550 and fine mode ratio (FMR550) data from MODIS were combined with aerosol index (AI) data from the Earth Probe TOMS and OMI satellite sensors, wind field data from the ERA-interim reanalysis and AOD550 data for various aerosol types from the GOCART model and the MACC reanalysis to quantify the relative contribution of different aerosol types (marine, dust, anthropogenic, fine-mode natural) to the total AOD550. The aerosol-cloud relations over the region were investigated with the use of the joint high resolution aerosol-cloud gridded dataset. Specifically, we focused on the seasonal relations between the cloud droplet number concentration (CDNC) and AOD550. The aerosol direct and first indirect radiative effect was then calculated for each aerosol type separately making use of the aerosol relative contribution to the total AOD550, the CDND-AOD550 relations and satellite-based parameterizations. The direct radiative effect was also quantified using simulations from a regional climate model (REGCM4), simulations with a radiative transfer model (SBDART) and the three methods were finally intervalidated.
NASA Astrophysics Data System (ADS)
Villagrasa, Carmen; Meylan, Sylvain; Gonon, Geraldine; Gruel, Gaëtan; Giesen, Ulrich; Bueno, Marta; Rabus, Hans
2017-09-01
In this work we present results obtained in the frame of the BioQuaRT project. The objective of the study was the correlation between the number of radiation-induced double strand breaks (DSB) of the DNA molecule and the probability of detecting nuclear foci after targeted microbeam irradiation of cells with protons and alpha particles of different LET. The former were obtained by simulation with new methods integrated into Geant4-DNA that permit calculating the number of DSB in a DNA target model induced by direct and indirect radiation effects. A particular focus was laid in this work on evaluating the influence of different criteria applied to the simulated results for predicting the formation of a direct SSB. Indeed, these criteria have an important impact on the predicted number of DSB per particle track and its dependence with LET. Among the criteria tested in this work, the case that a direct radiation interaction leads to a strand break if the cumulative energy deposited in the backbone part of one nucleotide exceeds a threshold of 17.5 eV leads to the best agreement with the relative LET dependence of number of radiation induced foci. Further calculations and experimental data are nevertheless needed in order to fix the simulation parameters and to help interpreting the biological experimental data observed by immunofluorescence in terms of the DSB complexity.
Shaping the third-harmonic radiation from silicon nanodimers
Wang, Lei; Kruk, Sergey; Xu, Lei; ...
2017-01-23
Recent progress in the study of resonant light confinement in high-index dielectric nanostructures suggests a new route for achieving efficient control of both electric and magnetic components of light. It also leads to the enhancement of nonlinear effects near electric and magnetic Mie resonances with an engineered radiation directionality. Furthermore we study the third-harmonic generation from dimers composed of pairs of two identical silicon nanoparticles and demonstrate, both numerically and experimentally, that the multipolar harmonic modes generated by the dimers near the Mie resonances allow the shaping of the directionality of nonlinear radiation.
NASA Technical Reports Server (NTRS)
Capo, M. A.; Mickle, R.
1975-01-01
A study was made to determine the dose rate at the payload position in the NERVA System (1) due to direct beam radiation and (2) due to the possible effect of fission products contained in the exhaust gases for various amounts of hydrogen propellant in the tank. Results indicate that the gamma radiation is more significant than the neutron flux. Under different assumptions the gamma contribution from the exhaust gases was 10 to 25 percent of total gamma flux.
A Binary-Encounter-Bethe Approach to Simulate DNA Damage by the Direct Effect
NASA Technical Reports Server (NTRS)
Plante, Ianik; Cucinotta, Francis A.
2013-01-01
The DNA damage is of crucial importance in the understanding of the effects of ionizing radiation. The main mechanisms of DNA damage are by the direct effect of radiation (e.g. direct ionization) and by indirect effect (e.g. damage by.OH radicals created by the radiolysis of water). Despite years of research in this area, many questions on the formation of DNA damage remains. To refine existing DNA damage models, an approach based on the Binary-Encounter-Bethe (BEB) model was developed[1]. This model calculates differential cross sections for ionization of the molecular orbitals of the DNA bases, sugars and phosphates using the electron binding energy, the mean kinetic energy and the occupancy number of the orbital. This cross section has an analytic form which is quite convenient to use and allows the sampling of the energy loss occurring during an ionization event. To simulate the radiation track structure, the code RITRACKS developed at the NASA Johnson Space Center is used[2]. This code calculates all the energy deposition events and the formation of the radiolytic species by the ion and the secondary electrons as well. We have also developed a technique to use the integrated BEB cross section for the bases, sugar and phosphates in the radiation transport code RITRACKS. These techniques should allow the simulation of DNA damage by ionizing radiation, and understanding of the formation of double-strand breaks caused by clustered damage in different conditions.
Nestle, U; Berlich, J
2006-05-01
In 2001 or 2002, the legislator made substantial alterations to the "Röntgenverordnung" [regulations governing use of roentgen ray radiation] and "Strahlenschutzverordnung" [regulations governing radiation protection]. This was done to bring German law in line with EU Directives 96/29/Euratom (basic safety standards for the protection of the health of workers and the general public against the dangers arising from ionizing radiation) and 97/43/Euratom (health protection of individuals against the dangers of ionizing radiation in relation to medical exposure). Proper use of radiation in medicine requires that those involved in its application are aware of the biological effects of radiation. When staff and others are protected good organization and appropriate technology at the workplace can achieve a great deal. In the new directives, the radiation protection for the patient is quantified and the responsibility of the physician is clearly pointed out. The most important aim is uniform quality throughout Europe in radiological diagnosis and radiation protection.
Nestle, U; Berlich, J
2006-08-01
In 2001 or 2002, the legislator made substantial alterations to the "Röntgenverordnung" [regulations governing use of roentgen ray radiation] and "Strahlenschutzverordnung" [regulations governing radiation protection]. This was done to bring German law in line with EU Directives 96/29/Euratom (basic safety standards for the protection of the health of workers and the general public against the dangers arising from ionizing radiation) and 97/43/Euratom (health protection of individuals against the dangers of ionizing radiation in relation to medical exposure). Proper use of radiation in medicine requires that those involved in its application are aware of the biological effect of radiation. When staff and others are protected good organization and appropriate technology at the workplace can achieve a great deal. In the new directives, the radiation protection for the patient is quantified and the responsibility of the physician is clearly pointed out. The most important aim is uniform quality throughout Europe in radiological diagnosis and radiation protection.
Diegeler, Sebastian; Hellweg, Christine E
2017-01-01
Ionizing radiation can affect the immune system in many ways. Depending on the situation, the whole body or parts of the body can be acutely or chronically exposed to different radiation qualities. In tumor radiotherapy, a fractionated exposure of the tumor (and surrounding tissues) is applied to kill the tumor cells. Currently, mostly photons, and also electrons, neutrons, protons, and heavier particles such as carbon ions, are used in radiotherapy. Tumor elimination can be supported by an effective immune response. In recent years, much progress has been achieved in the understanding of basic interactions between the irradiated tumor and the immune system. Here, direct and indirect effects of radiation on immune cells have to be considered. Lymphocytes for example are known to be highly radiosensitive. One important factor in indirect interactions is the radiation-induced bystander effect which can be initiated in unexposed cells by expression of cytokines of the irradiated cells and by direct exchange of molecules via gap junctions. In this review, we summarize the current knowledge about the indirect effects observed after exposure to different radiation qualities. The different immune cell populations important for the tumor immune response are natural killer cells, dendritic cells, and CD8+ cytotoxic T-cells. In vitro and in vivo studies have revealed the modulation of their functions due to ionizing radiation exposure of tumor cells. After radiation exposure, cytokines are produced by exposed tumor and immune cells and a modulated expression profile has also been observed in bystander immune cells. Release of damage-associated molecular patterns by irradiated tumor cells is another factor in immune activation. In conclusion, both immune-activating and -suppressing effects can occur. Enhancing or inhibiting these effects, respectively, could contribute to modified tumor cell killing after radiotherapy.
A global modeling study on carbonaceous aerosol microphysical characteristics and radiative forcing
NASA Astrophysics Data System (ADS)
Bauer, S. E.; Menon, S.; Koch, D.; Bond, T. C.; Tsigaridis, K.
2010-02-01
Recently, attention has been drawn towards black carbon aerosols as a short-term climate warming mitigation candidate. However the global and regional impacts of the direct, cloud-indirect and semi-direct forcing effects are highly uncertain, due to the complex nature of aerosol evolution and the way that mixed, aged aerosols interact with clouds and radiation. A detailed aerosol microphysical scheme, MATRIX, embedded within the GISS climate model is used in this study to present a quantitative assessment of the impact of microphysical processes involving black carbon, such as emission size distributions and optical properties on aerosol cloud activation and radiative forcing. Our best estimate for net direct and indirect aerosol radiative forcing between 1750 and 2000 is -0.56 W/m2. However, the direct and indirect aerosol effects are quite sensitive to the black and organic carbon size distribution and consequential mixing state. The net radiative forcing can vary between -0.32 to -0.75 W/m2 depending on these carbonaceous particle properties at emission. Assuming that sulfates, nitrates and secondary organics form a coating around a black carbon core, rather than forming a uniformly mixed particle, changes the overall net aerosol radiative forcing from negative to positive. Taking into account internally mixed black carbon particles let us simulate correct aerosol absorption. Black carbon absorption is amplified by sulfate and nitrate coatings, but even more strongly by organic coatings. Black carbon mitigation scenarios generally showed reduced radiative forcing when sources with a large proportion of black carbon, such as diesel, are reduced; however reducing sources with a larger organic carbon component as well, such as bio-fuels, does not necessarily lead to climate benefits.
NASA Astrophysics Data System (ADS)
Chen, Min
The increasing human activities have produced large amounts of air pollutants ejected into the atmosphere, in which atmospheric aerosols and tropospheric ozone are considered to be especially important because of their negative impacts on human health and their impacts on global climate through either their direct radiative effect or indirect effect on land-atmosphere CO2 exchange. This dissertation dedicates to quantifying and evaluating the aerosol and tropospheric ozone effects on global terrestrial ecosystem dynamics using a modeling approach. An ecosystem model, the integrated Terrestrial Ecosystem Model (iTem), is developed to simulate biophysical and biogeochemical processes in terrestrial ecosystems. A two-broad-band atmospheric radiative transfer model together with the Moderate-Resolution Imaging Spectroradiometer (MODIS) measured atmospheric parameters are used to well estimate global downward solar radiation and the direct and diffuse components in comparison with observations. The atmospheric radiative transfer modeling framework were used to quantify the aerosol direct radiative effect, showing that aerosol loadings cause 18.7 and 12.8 W m -2 decrease of direct-beam Photosynthetic Active Radiation (PAR) and Near Infrared Radiation (NIR) respectively, and 5.2 and 4.4 W m -2 increase of diffuse PAR and NIR, respectively, leading to a total 21.9 W m-2 decrease of total downward solar radiation over the global land surface during the period of 2003-2010. The results also suggested that the aerosol effect may be overwhelmed by clouds because of the stronger extinction and scattering ability of clouds. Applications of the iTem with solar radiation data and with or without considering the aerosol loadings shows that aerosol loading enhances the terrestrial productions [Gross Primary Production (GPP), Net Primary Production (NPP) and Net Ecosystem Production (NEP)] and carbon emissions through plant respiration (RA) in global terrestrial ecosystems over the period of 2003-2010. Ecosystem heterotrophic respiration (RH) was negatively affected by the aerosol loading. These results support previous conclusions of the advantage of aerosol light scattering effect on plant productions in other studies but suggest there is strong spatial variation. This study finds indirect aerosol effects on terrestrial ecosystem carbon dynamics through affecting plant phenology, thermal and hydrological environments. All these evidences suggested that the aerosol direct radiative effect on global terrestrial ecosystem carbon dynamics should be considered to better understand the global carbon cycle and climate change. An ozone sub-model is developed in this dissertation and fully coupled with iTem. The coupled model, named iTemO3 considers the processes of ozone stomatal deposition, plant defense to ozone influx, ozone damage and plant repairing mechanism. By using a global atmospheric chemical transport model (GACTM) estimated ground-level ozone concentration data, the model estimated global annual stomatal ozone deposition is 234.0 Tg O3 yr-1 and indicates which regions have high ozone damage risk. Different plant functional types, sunlit and shaded leaves are shown to have different responses to ozone. The model predictions suggest that ozone has caused considerable change on global terrestrial ecosystem carbon storage and carbon exchanges over the study period 2004-2008. The study suggests that uncertainty of the key parameters in iTemO3 could result in large errors in model predictions. Thus more experimental data for better model parameterization is highly needed.
The generation of gravitational waves. I - Weak-field sources
NASA Technical Reports Server (NTRS)
Thorne, K. S.; Kovacs, S. J.
1975-01-01
This paper derives and summarizes a 'plug-in-and-grind' formalism for calculating the gravitational waves emitted by any system with weak internal gravitational fields. If the internal fields have negligible influence on the system's motions, the formalism reduces to standard 'linearized theory'. Independent of the effects of gravity on the motions, the formalism reduces to the standard 'quadrupole-moment formalism' if the motions are slow and internal stresses are weak. In the general case, the formalism expresses the radiation in terms of a retarded Green's function for slightly curved spacetime and breaks the Green's function integral into five easily understood pieces: direct radiation, produced directly by the motions of the source; whump radiation, produced by the 'gravitational stresses' of the source; transition radiation, produced by a time-changing time delay ('Shapiro effect') in the propagation of the nonradiative 1/r field of the source; focusing radiation, produced when one portion of the source focuses, in a time-dependent way, the nonradiative field of another portion of the source; and tail radiation, produced by 'back-scatter' of the nonradiative field in regions of focusing.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chang, S.
Recent advances in cancer research have shed new light on the complex processes of how therapeutic radiation initiates changes at cellular, tissue, and system levels that may lead to clinical effects. These new advances may transform the way we use radiation to combat certain types of cancers. For the past two decades many technological advancements in radiation therapy have been largely based on the hypothesis that direct radiation-induced DNA double strand breaks cause cell death and thus tumor control and normal tissue damage. However, new insights have elucidated that in addition to causing cellular DNA damage, localized therapeutic radiation alsomore » initiates cascades of complex downstream biological responses in tissue that extend far beyond where therapeutic radiation dose is directly deposited. For instance, studies show that irradiated dying tumor cells release tumor antigens that can lead the immune system to a systemic anti-cancer attack throughout the body of cancer patient; targeted irradiation to solid tumor also increases the migration of tumor cells already in bloodstream, the seeds of potential metastasis. Some of the new insights may explain the long ago discovered but still unexplained non-localized radiation effects (bystander effect and abscopal effect) and the efficacy of spatially fractionated radiation therapy (microbeam radiation therapy and GRID therapy) where many “hot” and “cold” spots are intentionally created throughout the treatment volume. Better understanding of the mechanisms behind the non-localized radiation effects creates tremendous opportunities to develop new and integrated cancer treatment strategies that are based on radiotherapy, immunology, and chemotherapy. However, in the multidisciplinary effort to advance new radiobiology, there are also tremendous challenges including a lack of multidisciplinary researchers and imaging technologies for the microscopic radiation-induced responses. A better grasp of the essence of these advances in cancer biology research will give medical physicists a new perspective in daily clinical physics practice and in future radiation therapy technological development. Furthermore, academic medical physics should continue to be an integral part of the multidisciplinary cancer research community, harnessing our newly acquired understanding of radiation effects, and developing novel cost-effective treatment strategies to better combat cancer. Learning Objectives: Understand that localized radiation can lead to non-localized secondary effects such as radiation-induced immune response, bystander effect, and abscopal effect. Understand that the non-localized radiation effects may be harnessed to improve cancer treatment. Learn examples of physics participation in multidisciplinary research to advance cancer biology. Recognize the challenges and possibilities of physics applications in cancer research. Chang: NIH 5RC2CA148487-02 and 1U54CA151652-01 Graves: IDEA award (19IB-0106) from the California Breast Cancer Research Program (CBCRP), and by NIH P01 CA67166.« less
Impact of Changes in Diffuse Radiation on the Global Land Carbon Sink, 1901-2100
NASA Astrophysics Data System (ADS)
Mercado, L.; Bellouin, N.; Sitch, S.; Boucher, O.; Huntingford, C.; Wild, M.; Cox, P. M.
2009-04-01
Recent observational and theoretical studies have shown that changes in surface radiation that lead to increasing diffuse surface irradiance, enhance plant photosynthesis (Gu et al., 2003, Niyogi et al., 2004, Oliveira et al., 2007, Roderick et al., 2001). Solar radiation reaching the land surface has changed over the industrial era due to aerosols emitted from volcanoes and various anthropogenic sources (Kvalevag and Myhre, 2007). Such changes in total surface radiation are accompanied by changes in direct and diffuse surface solar radiation. Current global climate-carbon models do include the effects of changes in total surface radiation on the land biosphere but neglect the positive effects of increasing diffuse fraction on plant photosynthesis. In this study we estimate for the first time, the impact of variations in diffuse fraction on the land carbon sink using a global model (Mercado et al., 2007) modified to account for the effects of variations in both direct and diffuse radiation on canopy photosynthesis. We use meteorological forcing from the Climate Research Unit Data set. Additionally short wave and photosynthetic active radiation are reconstructed from the Hadley centre climate model, which accounts for the scattering and absorption of light by tropospheric and stratospheric aerosols and change in cloud properties due to indirect aerosol effects. References Gu L.H., Baldocchi D.D., Wofsy S.C., Munger J.W., Michalsky J.J., Urbanski S.P. & Boden T.A. (2003) Response of a deciduous forest to the Mount Pinatubo eruption: Enhanced photosynthesis. Science, 299, 2035-2038. M. M. Kvalevag and G. Myhre, J. Clim. 20, 4874 (2007). Mercado L.M., Huntingford C., Gash J.H.C., Cox P.M. & Jogireddy V. (2007) Improving the representation of radiation interception and photosynthesis for climate model applications. Tellus Series B-Chemical and Physical Meteorology, 59, 553-565. Niyogi D., Chang H.I., Saxena V.K., Holt T., Alapaty K., Booker F., Chen F., Davis K.J., Holben B., Matsui T., Meyers T., Oechel W.C., Pielke R.A., Wells R., Wilson K. & Xue Y.K. (2004) Direct observations of the effects of aerosol loading on net ecosystem CO2 exchanges over different landscapes. Geophysical Research Letters, 31. Oliveira P.H.F., Artaxo P., Pires C., De Lucca S., Procopio A., Holben B., Schafer J., Cardoso L.F., Wofsy S.C. & Rocha H.R. (2007) The effects of biomass burning aerosols and clouds on the CO2 flux in Amazonia. Tellus Series B-Chemical and Physical Meteorology, 59, 338-349. Roderick M.L., Farquhar G.D., Berry S.L. & Noble I.R. (2001) On the direct effect of clouds and atmospheric particles on the productivity and structure of vegetation. Oecologia, 129, 21-30.
Noise radiation directivity from a wind-tunnel inlet with inlet vanes and duct wall linings
NASA Technical Reports Server (NTRS)
Soderman, P. T.; Phillips, J. D.
1986-01-01
The acoustic radiation patterns from a 1/15th scale model of the Ames 80- by 120-Ft Wind Tunnel test section and inlet have been measured with a noise source installed in the test section. Data were acquired without airflow in the duct. Sound-absorbent inlet vanes oriented parallel to each other, or splayed with a variable incidence relative to the duct long axis, were evaluated along with duct wall linings. Results show that splayed vans tend to spread the sound to greater angles than those measured with the open inlet. Parallel vanes narrowed the high-frequency radiation pattern. Duct wall linings had a strong effect on acoustic directivity by attenuating wall reflections. Vane insertion loss was measured. Directivity results are compared with existing data from square ducts. Two prediction methods for duct radiation directivity are described: one is an empirical method based on the test data, and the other is a analytical method based on ray acoustics.
Mechanisms of the effect of VUV radiation on the microfungi
NASA Astrophysics Data System (ADS)
Zvereva, Galina; Kirtsideli, Irina; Machs, Eduard; Vangonen, Albert
2018-04-01
The mechanisms of the effect of vacuum ultraviolet (VUV) radiation (λ = 172 nm) on various types of microfungi spores were investigated. It is found that there are several parallel direct and indirect mechanisms, which lead to spores inactivation, including destruction of the cell wall and DNA by means of direct absorption of VUV radiation and by VUV photolysis reactive products. IR transmission spectra indicate the etching of the spore cell wall material with the predominant degradation of the polysaccharides. Electrophoresis of irradiated spores DNA shows heavy (about 20 000 pairs of nucleotides) and light fragments appearance. Experiments using an antioxidant (iodine) indicate the participation of reactive radicals in inactivation, which provide not less than 10% of inactivated cells
UV and ionizing radiations induced DNA damage, differences and similarities
NASA Astrophysics Data System (ADS)
Ravanat, Jean-Luc; Douki, Thierry
2016-11-01
Both UV and ionizing radiations damage DNA. Two main mechanisms, so-called direct and indirect pathways, are involved in the degradation of DNA induced by ionizing radiations. The direct effect of radiation corresponds to direct ionization of DNA (one electron ejection) whereas indirect effects are produced by reactive oxygen species generated through water radiolysis, including the highly reactive hydroxyl radicals, which damage DNA. UV (and visible) light damages DNA by again two distinct mechanisms. UVC and to a lesser extend UVB photons are directly absorbed by DNA bases, generating their excited states that are at the origin of the formation of pyrimidine dimers. UVA (and visible) light by interaction with endogenous or exogenous photosensitizers induce the formation of DNA damage through photosensitization reactions. The excited photosensitizer is able to induce either a one-electron oxidation of DNA (type I) or to produce singlet oxygen (type II) that reacts with DNA. In addition, through an energy transfer from the excited photosensitizer to DNA bases (sometime called type III mechanism) formation of pyrimidine dimers could be produced. Interestingly it has been shown recently that pyrimidine dimers are also produced by direct absorption of UVA light by DNA, even if absorption of DNA bases at these wavelengths is very low. It should be stressed that some excited photosensitizers (such as psoralens) could add directly to DNA bases to generate adducts. The review will described the differences and similarities in terms of damage formation (structure and mechanisms) between these two physical genotoxic agents.
Effect of reabsorbed recombination radiation on the saturation current of direct gap p-n junctions
NASA Technical Reports Server (NTRS)
Von Roos, O.; Mavromatis, H.
1984-01-01
The application of the radiative transfer theory for semiconductors to p-n homojunctions subject to low level injection conditions is discussed. By virtue of the interaction of the radiation field with free carriers across the depletion layer, the saturation current density in Shockley's expression for the diode current is reduced at high doping levels. The reduction, due to self-induced photon generation, is noticeable for n-type material owing to the small electron effective mass in direct band-gap III-V compounds. The effect is insignificant in p-type material. At an equilibrium electron concentration of 2 x 10 to the 18th/cu cm in GaAs, a reduction of the saturation current density by 15 percent is predicted. It is concluded that realistic GaAs p-n junctions possess a finite thickness.
Radiation pressure and air drag effects on the orbit of the balloon satellite 1963 30D
NASA Technical Reports Server (NTRS)
Slowey, J. W.
1974-01-01
Computed orbits of the balloon satellite 1963 30D are given every 2 days over an interval of 456 days near the beginning of the satellite's lifetime and an interval of 824 days near the end of its lifetime. The effects of radiation pressure on the satellite are examined in some detail. It is found that the variations in all the elements can be represented by use of a single parameter to specify the effect of diffuse reflection from the satellite's surface, and that this parameter remains constant, or nearly so, during the entire 7-year lifetime. Success in obtaining a consistent representation of the radiation-pressure effects is ascribed to the inclusion of the effects of terrestrial radiation pressure, using a model for the earth's albedo that includes seasonal and latitudinal variations. Anomalous effects in the orbital acceleration, as well as in the other elements, are represented quite well by including a small force at right angle to the solar direction and by allowing this to rotate about the solar direction. This implies that the satellite is aspherical, that it is rotating, and that the axis of rotation precesses.
NASA Technical Reports Server (NTRS)
Liu, Hongyu; Crawford, James; Ham, Seung-Hee; Zhang, Bo; Kato, Seiji; Voulgarakis, Apostolos; Chen, Gao; Fairlie, Duncan; Duncan, Bryan; Yantosca, Robert
2017-01-01
Clouds directly affect tropospheric photochemistry through modification of solar radiation that determines photolysis frequencies. This effect is an important component of global tropospheric chemistry-climate interaction, and its understanding is thus essential for predicting the feedback of climate change on tropospheric chemistry.
Quasi-analytical treatment of spatially averaged radiation transfer in complex terrain
NASA Astrophysics Data System (ADS)
Löwe, H.; Helbig, N.
2012-04-01
We provide a new quasi-analytical method to compute the topographic influence on the effective albedo of complex topography as required for meteorological, land-surface or climate models. We investigate radiative transfer in complex terrain via the radiosity equation on isotropic Gaussian random fields. Under controlled approximations we derive expressions for domain averages of direct, diffuse and terrain radiation and the sky view factor. Domain averaged quantities are related to a type of level-crossing probability of the random field which is approximated by longstanding results developed for acoustic scattering at ocean boundaries. This allows us to express all non-local horizon effects in terms of a local terrain parameter, namely the mean squared slope. Emerging integrals are computed numerically and fit formulas are given for practical purposes. As an implication of our approach we provide an expression for the effective albedo of complex terrain in terms of the sun elevation angle, mean squared slope, the area averaged surface albedo, and the direct-to-diffuse ratio of solar radiation. As an application, we compute the effective albedo for the Swiss Alps and discuss possible generalizations of the method.
Note: Measurement system for the radiative forcing of greenhouse gases in a laboratory scale.
Kawamura, Yoshiyuki
2016-01-01
The radiative forcing of the greenhouse gases has been studied being based on computational simulations or the observation of the real atmosphere meteorologically. In order to know the greenhouse effect more deeply and to study it from various viewpoints, the study on it in a laboratory scale is important. We have developed a direct measurement system for the infrared back radiation from the carbon dioxide (CO2) gas. The system configuration is similar with that of the practical earth-atmosphere-space system. Using this system, the back radiation from the CO2 gas was directly measured in a laboratory scale, which roughly coincides with meteorologically predicted value.
Elevated Frequency of Cataracts in Birds from Chernobyl
Mousseau, Timothy Alexander; Møller, Anders Pape
2013-01-01
Background Radiation cataracts develop as a consequence of the effects of ionizing radiation on the development of the lens of the eye with an opaque lens reducing or eliminating the ability to see. Therefore, we would expect cataracts to be associated with reduced fitness in free-living animals. Methodology/Principal Findings We investigated the incidence of lens opacities typical of cataracts in more than 1100 free-living birds in the Chernobyl region in relation to background radiation. The incidence of cataracts increased with level of background radiation both in analyses based on a dichotomous score and in analyses of continuous scores of intensity of cataracts. The odds ratio per unit change in the regressor was 0.722 (95% CI 0.648, 0.804), which was less than odds ratios from investigations of radiation cataracts in humans. The relatively small odds ratio may be due to increased mortality in birds with cataracts. We found a stronger negative relationship between bird abundance and background radiation when the frequency of cataracts was higher, but also a direct effect of radiation on abundance, suggesting that radiation indirectly affects abundance negatively through an increase in the frequency of cataracts in bird populations, but also through direct effects of radiation on other diseases, food abundance and interactions with other species. There was no increase in incidence of cataracts with increasing age, suggesting that yearlings and older individuals were similarly affected as is typical of radiation cataract. Conclusions/Significance These findings suggest that cataracts are an under-estimated cause of morbidity in free-living birds and, by inference, other vertebrates in areas contaminated with radioactive materials. PMID:23935827
On radiation emission from a microbunched beam with wavefront tilt and its experimental observation
NASA Astrophysics Data System (ADS)
Geloni, Gianluca; Kocharyan, Vitali; Saldin, Evgeni
2018-03-01
In this paper we compare experimental observations and theory of radiation emission from a microbunched beam with microbunching wavefront tilt with respect to the direction of motion. The theory refers to the work Tanaka et al. (2004) , which predicts, in this case, exponential suppression of coherent radiation along the kicked direction. The observations refer to a recent experiment performed at the LCLS (Nuhn et al., 2015; Lutman etal., 2016), where a microbunched beam was kicked by a bend and sent to a radiator undulator. The experiment resulted in the emission of strong coherent radiation that had its maximum along the kicked direction of motion, when the undulator parameter was detuned to a value larger than the nominal one. We first analyze the theory in detail, and we confirm the correctness of its derivation according to the conventional theory of radiation emission from charged particles. Subsequently, we look for possible peculiarities in the experiment, which may not be modeled by the theory. We show that only spurious effects are not accounted for. We conclude that the experiment defies explanation in terms of the conventional theory of radiation emission.
NASA Astrophysics Data System (ADS)
Yamasoe, M. A.; do Rosário, N. M. E.; Barros, K. M.
2017-01-01
We analyzed the variability of downward solar irradiance reaching the surface at São Paulo city, Brazil, and estimated the climatological aerosol and cloud radiative effects. Eleven years of irradiance were analyzed, from 2005 to 2015. To distinguish the aerosol from the cloud effect, the radiative transfer code LibRadtran was used to calculate downward solar irradiance. Two runs were performed, one considering only ozone and water vapor daily variability, with AOD set to zero and the second allowing the three variables to change, according to mean climatological values. The difference of the 24 h mean irradiance calculated with and without aerosol resulted in the shortwave aerosol direct radiative effect, while the difference between the measured and calculated, including the aerosol, represented the cloud effect. Results showed that, climatologically, clouds can be 4 times more effective than aerosols. The cloud shortwave radiative effect presented a maximum reduction of about -170 W m-2 in January and a minimum in July, of -37 W m-2. The aerosol direct radiative effect was maximum in spring, when the transport of smoke from the Amazon and central parts of South America is frequent toward São Paulo. Around mid-September, the 24 h radiative effect due to aerosol only was estimated to be -50 W m-2. Throughout the rest of the year, the mean aerosol effect was around -20 W m-2 and was attributed to local urban sources. The effect of the cloud fraction on the cloud modification factor, defined as the ratio of all-sky irradiation to cloudless sky irradiation, showed dependence on the cloud height. Low clouds presented the highest impact while the presence of high clouds only almost did not affect solar transmittance, even in overcast conditions.
The use of screening effects in modelling route-based daytime road surface temperature
NASA Astrophysics Data System (ADS)
Hu, Yumei; Almkvist, Esben; Lindberg, Fredrik; Bogren, Jörgen; Gustavsson, Torbjörn
2016-07-01
Winter road maintenance is essential for road safety. Accurate predictions of the road surface temperature (RST) and conditions can enhance the efficiency of winter road maintenance. Screening effects, which encompass shading effects and the influence of the sky-view factor ( ψ s ), influence RST distributions because they affect road surface radiation fluxes. In this work, light detection and ranging (Lidar) data are used to derive shadow patterns and ψ s values, and the resulting shadow patterns are used to model route-based RST distributions along two stretches of road in Sweden. The shading patterns and road surface radiation fluxes calculated from the Lidar data generally agreed well with measured RST values. Variation in land use types and the angle between the road direction and solar azimuth may introduce uncertainties, and accounting for these factors may improve the results obtained in certain cases. A simple shading model that only accounts for the direct radiation at the instant of measurement is often sufficient to provide reasonably accurate RST estimates. However, in certain cases, such as those involving measurements close to sunset, it is important to consider the radiation accumulated over several hours. The inclusion of ψ s improves the model performance even more in such cases. Overall, RST models based on the accumulated direct shortwave radiation offered an optimal balance of simplicity and accuracy. General radiation models were built for country road and highway environments, explaining up to 70 and 65 %, respectively, of the observed variation in RST along the corresponding stretches of road.
NASA Astrophysics Data System (ADS)
Vaillant de Guélis, Thibault; Chepfer, Hélène; Noel, Vincent; Guzman, Rodrigo; Dubuisson, Philippe; Winker, David M.; Kato, Seiji
2017-12-01
According to climate model simulations, the changing altitude of middle and high clouds is the dominant contributor to the positive global mean longwave cloud feedback. Nevertheless, the mechanisms of this longwave cloud altitude feedback and its magnitude have not yet been verified by observations. Accurate, stable, and long-term observations of a metric-characterizing cloud vertical distribution that are related to the longwave cloud radiative effect are needed to achieve a better understanding of the mechanism of longwave cloud altitude feedback. This study shows that the direct measurement of the altitude of atmospheric lidar opacity is a good candidate for the necessary observational metric. The opacity altitude is the level at which a spaceborne lidar beam is fully attenuated when probing an opaque cloud. By combining this altitude with the direct lidar measurement of the cloud-top altitude, we derive the effective radiative temperature of opaque clouds which linearly drives (as we will show) the outgoing longwave radiation. We find that, for an opaque cloud, a cloud temperature change of 1 K modifies its cloud radiative effect by 2 W m-2. Similarly, the longwave cloud radiative effect of optically thin clouds can be derived from their top and base altitudes and an estimate of their emissivity. We show with radiative transfer simulations that these relationships hold true at single atmospheric column scale, on the scale of the Clouds and the Earth's Radiant Energy System (CERES) instantaneous footprint, and at monthly mean 2° × 2° scale. Opaque clouds cover 35 % of the ice-free ocean and contribute to 73 % of the global mean cloud radiative effect. Thin-cloud coverage is 36 % and contributes 27 % of the global mean cloud radiative effect. The link between outgoing longwave radiation and the altitude at which a spaceborne lidar beam is fully attenuated provides a simple formulation of the cloud radiative effect in the longwave domain and so helps us to understand the longwave cloud altitude feedback mechanism.
NASA Astrophysics Data System (ADS)
Randrianalisoa, Jaona; Haussener, Sophia; Baillis, Dominique; Lipiński, Wojciech
2017-11-01
Radiative heat transfer is analyzed in participating media consisting of long cylindrical fibers with a diameter in the limit of geometrical optics. The absorption and scattering coefficients and the scattering phase function of the medium are determined based on the discrete-level medium geometry and optical properties of individual fibers. The fibers are assumed to be randomly oriented and positioned inside the medium. Two approaches are employed: a volume-averaged two-intensity approach referred to as multi-RTE approach and a homogenized single-intensity approach referred to as the single-RTE approach. Both approaches require effective properties, determined using direct Monte Carlo ray tracing techniques. The macroscopic radiative transfer equations (for single intensity or two volume-averaged intensities) with the corresponding effective properties are solved using Monte Carlo techniques and allow for the determination of the radiative flux distribution as well as overall transmittance and reflectance of the medium. The results are compared against predictions by the direct Monte Carlo simulation on the exact morphology. The effects of fiber volume fraction and optical properties on the effective radiative properties and the overall slab radiative characteristics are investigated. The single-RTE approach gives accurate predictions for high porosity fibrous media (porosity about 95%). The multi-RTE approach is recommended for isotropic fibrous media with porosity in the range of 79-95%.
NASA Astrophysics Data System (ADS)
Jolly, Arthur D.; Matoza, Robin S.; Fee, David; Kennedy, Ben M.; Iezzi, Alexandra M.; Fitzgerald, Rebecca H.; Austin, Allison C.; Johnson, Richard
2017-10-01
We obtained an unprecedented view of the acoustic radiation from persistent strombolian volcanic explosions at Yasur volcano, Vanuatu, from the deployment of infrasound sensors attached to a tethered aerostat. While traditional ground-based infrasound arrays may sample only a small portion of the eruption pressure wavefield, we were able to densely sample angular ranges of 200° in azimuth and 50° in takeoff angle by placing the aerostat at 38 tethered loiter positions around the active vent. The airborne data joined contemporaneously collected ground-based infrasound and video recordings over the period 29 July to 1 August 2016. We observe a persistent variation in the acoustic radiation pattern with average eastward directed root-mean-square pressures more than 2 times larger than in other directions. The observed radiation pattern may be related to both path effects from the crater walls, and source directionality.
NASA Astrophysics Data System (ADS)
Aebi, Christine; Gröbner, Julian; Kämpfer, Niklaus; Vuilleumier, Laurent
2017-11-01
The current study analyses the cloud radiative effect during the daytime depending on cloud fraction and cloud type at two stations in Switzerland over a time period of 3 to 5 years. Information on fractional cloud coverage and cloud type is retrieved from images taken by visible all-sky cameras. Cloud-base height (CBH) data are retrieved from a ceilometer and integrated water vapour (IWV) data from GPS measurements. The longwave cloud radiative effect (LCE) for low-level clouds and a cloud coverage of 8 oktas has a median value between 59 and 72 Wm-2. For mid- and high-level clouds the LCE is significantly lower. It is shown that the fractional cloud coverage, the CBH and IWV all have an influence on the magnitude of the LCE. These observed dependences have also been modelled with the radiative transfer model MODTRAN5. The relative values of the shortwave cloud radiative effect (SCErel) for low-level clouds and a cloud coverage of 8 oktas are between -90 and -62 %. Also here the higher the cloud is, the less negative the SCErel values are. In cases in which the measured direct radiation value is below the threshold of 120 Wm-2 (occulted sun) the SCErel decreases substantially, while cases in which the measured direct radiation value is larger than 120 Wm-2 (visible sun) lead to a SCErel of around 0 %. In 14 and 10 % of the cases in Davos and Payerne respectively a cloud enhancement has been observed with a maximum in the cloud class cirrocumulus-altocumulus at both stations. The calculated median total cloud radiative effect (TCE) values are negative for almost all cloud classes and cloud coverages.
The electromagnetic radiation from simple sources in the presence of a homogeneous dielectric sphere
NASA Technical Reports Server (NTRS)
Mason, V. B.
1973-01-01
In this research, the effect of a homogeneous dielectric sphere on the electromagnetic radiation from simple sources is treated as a boundary value problem, and the solution is obtained by the technique of dyadic Green's functions. Exact representations of the electric fields in the various regions due to a source located inside, outside, or on the surface of a dielectric sphere are formulated. Particular attention is given to the effect of sphere size, source location, dielectric constant, and dielectric loss on the radiation patterns and directivity of small spheres (less than 5 wavelengths in diameter) using the Huygens' source excitation. The computed results are found to closely agree with those measured for waveguide-excited plexiglas spheres. Radiation patterns for an extended Huygens' source and for curved electric dipoles located on the sphere's surface are also presented. The resonance phenomenon associated with the dielectric sphere is studied in terms of the modal representation of the radiated fields. It is found that when the sphere is excited at certain frequencies, much of the energy is radiated into the sidelobes. The addition of a moderate amount of dielectric loss, however, quickly attenuates this resonance effect. A computer program which may be used to calculate the directivity and radiation pattern of a Huygens' source located inside or on the surface of a lossy dielectric sphere is listed.
Effects of aerosol from biomass burning on the global radiation budget
NASA Technical Reports Server (NTRS)
Penner, Joyce E.; Dickinson, Robert E.; O'Neill, Christine A.
1992-01-01
An analysis is made of the likely contribution of smoke particles from biomass burning to the global radiation balance. These particles act to reflect solar radiation directly; they also can act as cloud condensation nuclei, increasing the reflectivity of clouds. Together these effects, although uncertain, may add up globally to a cooling effect as large as 2 watts per square meter, comparable to the estimated contribution to sulfate aerosols. Anthropogenic increases of smoke emission thus may have helped weaken the net greenhouse warming from anthropogenic trace gases.
TU-CD-303-05: Unveiling Tumor Heterogeneity by Molecular Imaging
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jeraj, R.
2015-06-15
Recent advances in cancer research have shed new light on the complex processes of how therapeutic radiation initiates changes at cellular, tissue, and system levels that may lead to clinical effects. These new advances may transform the way we use radiation to combat certain types of cancers. For the past two decades many technological advancements in radiation therapy have been largely based on the hypothesis that direct radiation-induced DNA double strand breaks cause cell death and thus tumor control and normal tissue damage. However, new insights have elucidated that in addition to causing cellular DNA damage, localized therapeutic radiation alsomore » initiates cascades of complex downstream biological responses in tissue that extend far beyond where therapeutic radiation dose is directly deposited. For instance, studies show that irradiated dying tumor cells release tumor antigens that can lead the immune system to a systemic anti-cancer attack throughout the body of cancer patient; targeted irradiation to solid tumor also increases the migration of tumor cells already in bloodstream, the seeds of potential metastasis. Some of the new insights may explain the long ago discovered but still unexplained non-localized radiation effects (bystander effect and abscopal effect) and the efficacy of spatially fractionated radiation therapy (microbeam radiation therapy and GRID therapy) where many “hot” and “cold” spots are intentionally created throughout the treatment volume. Better understanding of the mechanisms behind the non-localized radiation effects creates tremendous opportunities to develop new and integrated cancer treatment strategies that are based on radiotherapy, immunology, and chemotherapy. However, in the multidisciplinary effort to advance new radiobiology, there are also tremendous challenges including a lack of multidisciplinary researchers and imaging technologies for the microscopic radiation-induced responses. A better grasp of the essence of these advances in cancer biology research will give medical physicists a new perspective in daily clinical physics practice and in future radiation therapy technological development. Furthermore, academic medical physics should continue to be an integral part of the multidisciplinary cancer research community, harnessing our newly acquired understanding of radiation effects, and developing novel cost-effective treatment strategies to better combat cancer. Learning Objectives: Understand that localized radiation can lead to non-localized secondary effects such as radiation-induced immune response, bystander effect, and abscopal effect. Understand that the non-localized radiation effects may be harnessed to improve cancer treatment. Learn examples of physics participation in multidisciplinary research to advance cancer biology. Recognize the challenges and possibilities of physics applications in cancer research. Chang: NIH 5RC2CA148487-02 and 1U54CA151652-01 Graves: IDEA award (19IB-0106) from the California Breast Cancer Research Program (CBCRP), and by NIH P01 CA67166.« less
Fate of products of degradation processes: consequences for climatic change.
Slanina, J; ten Brink, H M; Khlystov, A
1999-03-01
The end products of atmospheric degradation are not only CO2 and H2O but also sulfate and nitrate depending on the chemical composition of the substances which are subject to degradation processes. Atmospheric degradation has thus a direct influence on the radiative balance of the earth not only due to formation of greenhouse gases but also of aerosols. Aerosols of a diameter of 0.1 to 2 micrometer, reflect short wave sunlight very efficiently leading to a radiative forcing which is estimated to be about -0.8 watt per m2 by IPCC. Aerosols also influence the radiative balance by way of cloud formation. If more aerosols are present, clouds are formed with more and smaller droplets and these clouds have a higher albedo and are more stable compared to clouds with larger droplets. Not only sulfate, but also nitrate and polar organic compounds, formed as intermediates in degradation processes, contribute to this direct and indirect aerosol effect. Estimates for the Netherlands indicate a direct effect of -4 watt m-2 and an indirect effect of as large as -5 watt m-2. About one third is caused by sulfates, one third by nitrates and last third by polar organic compounds. This large radiative forcing is obviously non-uniform and depends on local conditions.
Aerosol microphysical and radiative effects on continental cloud ensembles
NASA Astrophysics Data System (ADS)
Wang, Yuan; Vogel, Jonathan M.; Lin, Yun; Pan, Bowen; Hu, Jiaxi; Liu, Yangang; Dong, Xiquan; Jiang, Jonathan H.; Yung, Yuk L.; Zhang, Renyi
2018-02-01
Aerosol-cloud-radiation interactions represent one of the largest uncertainties in the current climate assessment. Much of the complexity arises from the non-monotonic responses of clouds, precipitation and radiative fluxes to aerosol perturbations under various meteorological conditions. In this study, an aerosol-aware WRF model is used to investigate the microphysical and radiative effects of aerosols in three weather systems during the March 2000 Cloud Intensive Observational Period campaign at the US Southern Great Plains. Three simulated cloud ensembles include a low-pressure deep convective cloud system, a collection of less-precipitating stratus and shallow cumulus, and a cold frontal passage. The WRF simulations are evaluated by several ground-based measurements. The microphysical properties of cloud hydrometeors, such as their mass and number concentrations, generally show monotonic trends as a function of cloud condensation nuclei concentrations. Aerosol radiative effects do not influence the trends of cloud microphysics, except for the stratus and shallow cumulus cases where aerosol semi-direct effects are identified. The precipitation changes by aerosols vary with the cloud types and their evolving stages, with a prominent aerosol invigoration effect and associated enhanced precipitation from the convective sources. The simulated aerosol direct effect suppresses precipitation in all three cases but does not overturn the aerosol indirect effect. Cloud fraction exhibits much smaller sensitivity (typically less than 2%) to aerosol perturbations, and the responses vary with aerosol concentrations and cloud regimes. The surface shortwave radiation shows a monotonic decrease by increasing aerosols, while the magnitude of the decrease depends on the cloud type.
Impact of Radiation Biology on Fundamental Insights in Biology
DOE R&D Accomplishments Database
Setlow, Richard B.
1982-07-27
Research supported by OHER [Office of Health and Environmental Research] and its predecessors has as one of its major goals an understanding of the effects of radiation at low doses and dose rates on biological systems, so as to predict their effects on humans. It is not possible to measure such effects directly. They must be predicted from basic knowledge on how radiation affects cellular components such as DNA and membranes and how cells react to such changes. What is the probability of radiation producing human mutations and what are the probabilities of radiation producing cancer? The end results of such studies are radiation exposure standards for workers and for the general population. An extension of these goals is setting standards for exposure to chemicals involved in various energy technologies. This latter problem is much more difficult because chemical dosimetry is a primitive state compared to radiation dosimetry.
The Effect of Direct Solar Radiation Pressure on a Spacecraft of Complex Shape
NASA Astrophysics Data System (ADS)
El-Saftawy, M. I.; Ahmed, M. K. M.; Helali, Y. E.
1998-07-01
The canonical equations of motion of a spacecraft of complex shape under the joint effects of earth oblateness and direct solar radiation pressure are formulated. The shape of the satellite is modeled as an axisymmetric body plus despun antenna emitting or receiving a radio beam which is suitable to describe the main effects for the telecommunication satellites. The attitude of the satellite is assumed stabilized such that the axis of the symmetric part be along the tangent to the orbit. The Hamiltonian is developed in terms of the Delaunay elements augmented so as to remove the time dependence of the Hamiltonian.
NASA Astrophysics Data System (ADS)
Mallet, M.; Roger, J. C.; Dubuisson, P.; Putaud, J. P.; van Dingenen, R.; Despiau, S.
Radiative forcing by aerosol particles is one of the largest source of uncertainties in predicting climate change (IPCC, 2001). Indeed, quantitative estimates of this effect are still uncertain due to little knowledge of these atmospheric particles. Atmospheric particles influence the Earth's radiation balance both directly and indirectly. The indi- rect effect denotes the effect of aerosols acting as cloud condensation nuclei, possibly modifying cloud albedo and cloud lifetime. The direct effect is due to scattering and absorption of radiation and each of these processes depends mainly on the refractive index and the size distribution of aerosol particles. During the ESCOMPTE campaign, which took place in coastal Mediterranean area during the summer 2001, we estimated these aerosol micro-physical properties during a pollution event at two different sites. The first is an urban site (the city of Marseille), and the second is a rural area located fifty kilometers inland. The aerosol size distribution was measured with an SMPS for the particles with radii < 1 µm, and an optical counter for r > 1 µm. The chemi- cal composition (including different ionic compounds , dust, elemental and organic carbon) was deduced from chromatography analysis. The aerosol optical properties calculated from measured aerosol physical and chemical properties at ground level (from Mie theory) are used as input to a shortwave radiative transfer model. Then, this model is used to calculate the diurnally averaged direct aerosol forcing at surface and to compare this values with those measured from the ARAT aircraft and surface pyranometer during the campaign.
Aerosol Retrievals Using Channel 1 and 2 AVHRR Data
NASA Technical Reports Server (NTRS)
Mishchenko, Michael I.; Geogdzhayev, Igor V.; Cairns, Brian; Rossow, William B.
1999-01-01
The effect of tropospheric aerosols on global climate via the direct and indirect radiative forcings is one of the largest remaining uncertainties in climate change studies. Current assessments of the direct aerosol radiative effect mainly focus on sulfate aerosols. It has become clear, however, that other aerosol types like soil dust and smoke from biomass burning are also likely to be important climate forcing factors. The magnitude and even the sign of the climate forcing caused by these aerosol types is still unknown. General circulation models (GCMs) can be used to estimate the climatic effect of the direct radiative forcing by tropospheric and stratospheric aerosols. Aerosol optical properties are already parameterized in the Goddard Institute for Space Studies GCM. Once the global distribution of aerosol properties (optical thickness, size distribution, and chemical composition) is available, the calculation of the direct aerosol forcing is rather straighfforward. However, estimates of the indirect aerosol effect require additional knowledge of the physics and chemistry of aerosol-cloud interactions which are still poorly understood. One of the main objectives of the Global Aerosol Climatology Project, established in 1998 as a joint initiative of NASA's Radiation Science Program and GEWEX, is to infer the global distribution of aerosols, their properties, and their seasonal and interannual variations for the full period of available satellite data. This will be accomplished primarily through a systematic application of multichannel aerosol retrieval algorithms to existing satellite data and advanced 3-dimensional aerosol chemistry/transport models. In this paper we outline the methodology of analyzing channel 1 and 2 AVHRR radiance data over the oceans and describe preliminary retrieval results.
Mechanism of SOA formation determines magnitude of radiative effects
NASA Astrophysics Data System (ADS)
Zhu, Jialei; Penner, Joyce E.; Lin, Guangxing; Zhou, Cheng; Xu, Li; Zhuang, Bingliang
2017-11-01
Secondary organic aerosol (SOA) nearly always exists as an internal mixture, and the distribution of this mixture depends on the formation mechanism of SOA. A model is developed to examine the influence of using an internal mixing state based on the mechanism of formation and to estimate the radiative forcing of SOA in the future. For the present day, 66% of SOA is internally mixed with sulfate, while 34% is internally mixed with primary soot. Compared with using an external mixture, the direct effect of SOA is decreased due to the decrease in total aerosol surface area and the increase of absorption efficiency. Aerosol number concentrations are sharply reduced, and this is responsible for a large decrease in the cloud albedo effect. Internal mixing decreases the radiative effect of SOA by a factor of >4 compared with treating SOA as an external mixture. The future SOA burden increases by 24% due to CO2 increases and climate change, leading to a total (direct plus cloud albedo) radiative forcing of ‑0.05 W m‑2. When the combined effects of changes in climate, anthropogenic emissions, and land use are included, the SOA forcing is ‑0.07 W m‑2, even though the SOA burden only increases by 6.8%. This is caused by the substantial increase of SOA associated with sulfate in the Aitken mode. The Aitken mode increase contributes to the enhancement of first indirect radiative forcing, which dominates the total radiative forcing.
Mechanism of SOA formation determines magnitude of radiative effects
Zhu, Jialei; Penner, Joyce E.; Lin, Guangxing; ...
2017-11-13
Secondary organic aerosol (SOA) nearly always exists as an internal mixture and the distribution of this mixture depends on the formation mechanism of SOA. A model is developed to examine the influence of using an internal mixing states based on the mechanism of formation and to estimate the radiative forcing of SOA in the future. For the present day, 66 % of SOA is internally mixed with sulfate, while 34 % is internally mixed with primary soot. When compared with using an external mixture, the direct effect of SOA is decreased, due to the decrease of total aerosol surface areamore » and the increase of absorption efficiency. Aerosol number concentrations are sharply reduced and this is responsible for a large decrease in the cloud albedo effect. In total, internal mixing suppresses the radiative effect of SOA by a factor of >4 compared to treating SOA as an external mixture. The future SOA burden increases by 24% due to CO2 increases and climate change, leading to a total (direct plus cloud albedo) radiative forcing of -0.05 W m-2. When the combined effects of changes in climate, anthropogenic emissions and land use are included, the SOA forcing is -0.07 W m-2, even though the SOA burden only increases by 6.8%. This is caused by the substantial increase of SOA associated with sulfate in the Aitken mode. The Aitken mode increase contributes to the enhancement of first indirect radiative forcing, which dominates the total radiative forcing.« less
Mechanism of SOA formation determines magnitude of radiative effects
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhu, Jialei; Penner, Joyce E.; Lin, Guangxing
Secondary organic aerosol (SOA) nearly always exists as an internal mixture and the distribution of this mixture depends on the formation mechanism of SOA. A model is developed to examine the influence of using an internal mixing states based on the mechanism of formation and to estimate the radiative forcing of SOA in the future. For the present day, 66 % of SOA is internally mixed with sulfate, while 34 % is internally mixed with primary soot. When compared with using an external mixture, the direct effect of SOA is decreased, due to the decrease of total aerosol surface areamore » and the increase of absorption efficiency. Aerosol number concentrations are sharply reduced and this is responsible for a large decrease in the cloud albedo effect. In total, internal mixing suppresses the radiative effect of SOA by a factor of >4 compared to treating SOA as an external mixture. The future SOA burden increases by 24% due to CO2 increases and climate change, leading to a total (direct plus cloud albedo) radiative forcing of -0.05 W m-2. When the combined effects of changes in climate, anthropogenic emissions and land use are included, the SOA forcing is -0.07 W m-2, even though the SOA burden only increases by 6.8%. This is caused by the substantial increase of SOA associated with sulfate in the Aitken mode. The Aitken mode increase contributes to the enhancement of first indirect radiative forcing, which dominates the total radiative forcing.« less
Mechanism of SOA Formation Determines Magnitude of Radiative Effects
NASA Astrophysics Data System (ADS)
Zhu, J.; Penner, J.; Lin, G.; Zhou, C.
2017-12-01
Secondary organic aerosol (SOA) nearly always exists as an internal mixture and the distribution of this mixture depends on the formation mechanism of SOA. A model is developed to examine the influence of using an internal mixing states based on the mechanism of formation and to estimate the radiative forcing of SOA in the future. For the present day, 66 % of SOA is internally mixed with sulfate, while 34 % is internally mixed with primary soot. When compared with using an external mixture, the direct effect of SOA is decreased, due to the decrease of total aerosol surface area and the increase of absorption efficiency. Aerosol number concentrations are sharply reduced and this is responsible for a large decrease in the cloud albedo effect. In total, internal mixing suppresses the radiative effect of SOA by a factor of >4 compared to treating SOA as an external mixture. The future SOA burden increases by 24% due to CO2 increases and climate change, leading to a total (direct plus cloud albedo) radiative forcing of -0.05 W m-2. When the combined effects of changes in climate, anthropogenic emissions and land use are included, the SOA forcing is -0.07 W m-2, even though the SOA burden only increases by 6.8%. This is caused by the substantial increase of SOA associated with sulfate in the Aitken mode. The Aitken mode increase contributes to the enhancement of first indirect radiative forcing, which dominates the total radiative forcing.
Mechanism of SOA formation determines magnitude of radiative effects
Penner, Joyce E.; Lin, Guangxing; Zhou, Cheng; Xu, Li; Zhuang, Bingliang
2017-01-01
Secondary organic aerosol (SOA) nearly always exists as an internal mixture, and the distribution of this mixture depends on the formation mechanism of SOA. A model is developed to examine the influence of using an internal mixing state based on the mechanism of formation and to estimate the radiative forcing of SOA in the future. For the present day, 66% of SOA is internally mixed with sulfate, while 34% is internally mixed with primary soot. Compared with using an external mixture, the direct effect of SOA is decreased due to the decrease in total aerosol surface area and the increase of absorption efficiency. Aerosol number concentrations are sharply reduced, and this is responsible for a large decrease in the cloud albedo effect. Internal mixing decreases the radiative effect of SOA by a factor of >4 compared with treating SOA as an external mixture. The future SOA burden increases by 24% due to CO2 increases and climate change, leading to a total (direct plus cloud albedo) radiative forcing of −0.05 W m−2. When the combined effects of changes in climate, anthropogenic emissions, and land use are included, the SOA forcing is −0.07 W m−2, even though the SOA burden only increases by 6.8%. This is caused by the substantial increase of SOA associated with sulfate in the Aitken mode. The Aitken mode increase contributes to the enhancement of first indirect radiative forcing, which dominates the total radiative forcing. PMID:29133426
Mechanism of SOA formation determines magnitude of radiative effects.
Zhu, Jialei; Penner, Joyce E; Lin, Guangxing; Zhou, Cheng; Xu, Li; Zhuang, Bingliang
2017-11-28
Secondary organic aerosol (SOA) nearly always exists as an internal mixture, and the distribution of this mixture depends on the formation mechanism of SOA. A model is developed to examine the influence of using an internal mixing state based on the mechanism of formation and to estimate the radiative forcing of SOA in the future. For the present day, 66% of SOA is internally mixed with sulfate, while 34% is internally mixed with primary soot. Compared with using an external mixture, the direct effect of SOA is decreased due to the decrease in total aerosol surface area and the increase of absorption efficiency. Aerosol number concentrations are sharply reduced, and this is responsible for a large decrease in the cloud albedo effect. Internal mixing decreases the radiative effect of SOA by a factor of >4 compared with treating SOA as an external mixture. The future SOA burden increases by 24% due to CO 2 increases and climate change, leading to a total (direct plus cloud albedo) radiative forcing of -0.05 W m -2 When the combined effects of changes in climate, anthropogenic emissions, and land use are included, the SOA forcing is -0.07 W m -2 , even though the SOA burden only increases by 6.8%. This is caused by the substantial increase of SOA associated with sulfate in the Aitken mode. The Aitken mode increase contributes to the enhancement of first indirect radiative forcing, which dominates the total radiative forcing. Copyright © 2017 the Author(s). Published by PNAS.
NASA Technical Reports Server (NTRS)
Christopher, Sundar A.; Wang, Min; Kliche, Donna V.; Berendes, Todd; Welch, Ronald M.; Yang, S.K.
1997-01-01
Atmospheric aerosol particles, both natural and anthropogenic are important to the earth's radiative balance. Therefore it is important to provide adequate validation information on the spatial, temporal and radiative properties of aerosols. This will enable us to predict realistic global estimates of aerosol radiative effects more confidently. The current study utilizes 66 AVHRR LAC (Local Area Coverage) and coincident Earth Radiation Budget Experiment (ERBE) images to characterize the fires, smoke and radiative forcings of biomass burning aerosols over four major ecosystems of South America.
The directivity of the sound radiation from panels and openings.
Davy, John L
2009-06-01
This paper presents a method for calculating the directivity of the radiation of sound from a panel or opening, whose vibration is forced by the incidence of sound from the other side. The directivity of the radiation depends on the angular distribution of the incident sound energy in the room or duct in whose wall or end the panel or opening occurs. The angular distribution of the incident sound energy is predicted using a model which depends on the sound absorption coefficient of the room or duct surfaces. If the sound source is situated in the room or duct, the sound absorption coefficient model is used in conjunction with a model for the directivity of the sound source. For angles of radiation approaching 90 degrees to the normal to the panel or opening, the effect of the diffraction by the panel or opening, or by the finite baffle in which the panel or opening is mounted, is included. A simple empirical model is developed to predict the diffraction of sound into the shadow zone when the angle of radiation is greater than 90 degrees to the normal to the panel or opening. The method is compared with published experimental results.
NASA Technical Reports Server (NTRS)
Churchill, Dean D.; Houze, Robert A., Jr.
1991-01-01
A twi-dimensional kinematic model has been used to diagnose the thermodynamic, water vapor, and hydrometeor fields of the stratiform clouds associated with a mesoscale tropical cloud cluster. The model incorporates ice- and water-cloud microphysics, visible and infrared radiation, and convective adjustment. It is intended to determine the relative contributions of radiation, mycrophysics, and turbulence to diabatic heating, and the effects that radiation has on the water budget of the cluster in the absence of dynamical interactions. The model has been initialized with thermodynamic fields and wind velocities diagnosed from a GATE tropical squall line. It is found that radiation does not directly affect the water budget of the stratiform region, and any radiative effect on hydrometeors must involve interaction with dynamics.
NASA Astrophysics Data System (ADS)
Kocifaj, Miroslav; Gueymard, Christian A.
2011-02-01
Aerosol optical depth (AOD) has a crucial importance for estimating the optical properties of the atmosphere, and is constantly present in optical models of aerosol systems. Any error in aerosol optical depth (∂AOD) has direct and indirect consequences. On the one hand, such errors affect the accuracy of radiative transfer models (thus implying, e.g., potential errors in the evaluation of radiative forcing by aerosols). Additionally, any error in determining AOD is reflected in the retrieved microphysical properties of aerosol particles, which might therefore be inaccurate. Three distinct effects (circumsolar radiation, optical mass, and solar disk's brightness distribution) affecting ∂AOD are qualified and quantified in the present study. The contribution of circumsolar (CS) radiation to the measured flux density of direct solar radiation has received more attention than the two other effects in the literature. It varies rapidly with meteorological conditions and size distribution of the aerosol particles, but also with instrument field of view. Numerical simulations of the three effects just mentioned were conducted, assuming otherwise "perfect" experimental conditions. The results show that CS is responsible for the largest error in AOD, while the effect of brightness distribution (BD) has only a negligible impact. The optical mass (OM) effect yields negligible errors in AOD generally, but noticeable errors for low sun (within 10° of the horizon). In general, the OM and BD effects result in negative errors in AOD (i.e. the true AOD is smaller than that of the experimental determination), conversely to CS. Although the rapid increase in optical mass at large zenith angles can change the sign of ∂AOD, the CS contribution frequently plays the leading role in ∂AOD. To maximize the accuracy in AOD retrievals, the CS effect should not be ignored. In practice, however, this effect can be difficult to evaluate correctly unless the instantaneous aerosols size distribution is known from, e.g., inversion techniques.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Martinez-Ballarin, Roberto
The aim of this document is to study the effect of radiation damage on the silicon sensors. The reflection of the effect of radiation can be observed in two fundamental parameters of the detector: the bias current and the bias voltage. The leakage current directly affects the noise, while the bias voltage is required to collect the maximum signal deposited by the charged particle.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fu, Qiang; Comstock, Jennifer
The overall objective of this ASR funded project is to investigate the role of cloud radiative effects, especially those associated with tropical thin cirrus clouds in the tropical tropopause layer, by analyzing the ARM observations combined with numerical models. In particular, we have processed and analyzed the observations from the Raman lidar at the ARM SGP and TWP sites. In the tenure of the project (8/15/2013 – 8/14/2016 and with a no-cost extension to 8/14/2017), we have been concentrating on (i) developing an automated feature detection scheme of clouds and aerosols for the ARM Raman lidar; (ii) developing an automatedmore » retrieval of cloud and aerosol extinctions for the ARM Raman lidar; (iii) investigating cloud radiative effects based on the observations on the simulated temperatures in the tropical tropopause layer using a radiative-convective model; and (iv) examining the effect of changes of atmospheric composition on the tropical lower-stratospheric temperatures. In addition, we have examined the biases in the CALIPSO-inferred aerosol direct radiative effects using ground-based Raman lidars at the ARM SGP and TWP sites, and estimated the impact of lidar detection sensitivity on assessing global aerosol direct radiative effects. We have also investigated the diurnal cycle of clouds and precipitation at the ARM site using the cloud radar observations along with simulations from the multiscale modeling framework. The main results of our research efforts are reported in the six referred journal publications that acknowledge the DOE Grant DE-SC0010557.« less
Proteomic overview and perspectives of the radiation-induced bystander effects.
Chevalier, François; Hamdi, Dounia Houria; Saintigny, Yannick; Lefaix, Jean-Louis
2015-01-01
Radiation proteomics is a recent, promising and powerful tool to identify protein markers of direct and indirect consequences of ionizing radiation. The main challenges of modern radiobiology is to predict radio-sensitivity of patients and radio-resistance of tumor to be treated, but considerable evidences are now available regarding the significance of a bystander effect at low and high doses. This "radiation-induced bystander effect" (RIBE) is defined as the biological responses of non-irradiated cells that received signals from neighboring irradiated cells. Such intercellular signal is no more considered as a minor side-effect of radiotherapy in surrounding healthy tissue and its occurrence should be considered in adapting radiotherapy protocols, to limit the risk for radiation-induced secondary cancer. There is no consensus on a precise designation of RIBE, which involves a number of distinct signal-mediated effects within or outside the irradiated volume. Indeed, several cellular mechanisms were proposed, including the secretion of soluble factors by irradiated cells in the extracellular matrix, or the direct communication between irradiated and neighboring non-irradiated cells via gap junctions. This phenomenon is observed in a context of major local inflammation, linked with a global imbalance of oxidative metabolism which makes its analysis challenging using in vitro model systems. In this review article, the authors first define the radiation-induced bystander effect as a function of radiation type, in vitro analysis protocols, and cell type. In a second time, the authors present the current status of protein biomarkers and proteomic-based findings and discuss the capacities, limits and perspectives of such global approaches to explore these complex intercellular mechanisms. Copyright © 2014 Elsevier B.V. All rights reserved.
Investigation of radiative interactions in supersonic internal flows
NASA Technical Reports Server (NTRS)
Tiwari, Surendra N.; Thomas, A. M.
1991-01-01
Analyses and numerical procedures are presented to study the radiative interactions of absorbing emitting species in chemically reacting supersonic flow in various ducts. The 2-D time dependent Navier-Stokes equations in conjunction with radiative flux equation are used to study supersonic flows undergoing finite rate chemical reaction in a hydrogen air system. The specific problem considered is the flow of premixed radiating gas between parallel plates. Specific attention was directed toward studying the radiative contribution of H2O, OH, and NO under realistic physical and flow conditions. Results are presented for the radiative flux obtained for different gases and for various combination of these gases. The problem of chemically reacting and radiating flows was solved for the flow of premixed hydrogen-air through a 10 deg compression ramp. Results demonstrate that the radiative interaction increases with an increase in pressure, temperature, amount of participating species, plate spacing, and Mach number. Most of the energy, however, is transferred by convection in the flow direction. In general the results indicate that radiation can have a significant effect on the entire flow field.
Sensitivity of Salivary Glands to Radiation
Grundmann, O.; Mitchell, G.C.; Limesand, K.H.
2009-01-01
Radiation therapy for head and neck cancer causes significant secondary side-effects in normal salivary glands, resulting in diminished quality of life for these individuals. Salivary glands are exquisitely sensitive to radiation and display acute and chronic responses to radiotherapy. This review will discuss clinical implications of radiosensitivity in normal salivary glands, compare animal models used to investigate radiation-induced salivary gland damage, address therapeutic advances, and project future directions in the field. PMID:19783796
Radiation effects on Brassica seeds and seedlings
NASA Astrophysics Data System (ADS)
Deoli, Naresh; Hasenstein, Karl H.
2016-07-01
Space radiation consists of high energy charged particles and affects biological systems, but because of its stochastic, non-directional nature is difficult to replicate on Earth. Radiation damages biological systems acutely at high doses or cumulatively at low doses through progressive changes in DNA organization. These damages lead to death or cause of mutations. While radiation biology typically focuses on mammalian or human systems, little is known as to how radiation affects plants. In addition, energetic ion beams are widely used to generate new mutants in plants considering their high-LET (Linear Energy Transfer) as compared to gamma rays and X-rays. Understanding the effect of ionizing radiation on plant provides a basis for studying effects of radiation on biological systems and will help mitigate (space) radiation damage in plants. We exposed dry and imbibed Brassica rapa seeds and seedling roots to proton beams of varying qualities and compared the theoretical penetration range of different energy levels with observable growth response. We used 1, 2 and 3 MeV protons in air at the varying fluences to investigate the effect of direct irradiation on the seeds (1012 - 1015 ions/cm2) and seedlings (1013 ions/cm2). The range of protons in the tissue was calculated using Monte-Carlo based SRIM (Stopping and Range of Ions in Matter) software. The simulation and biological results indicate that ions did not penetrate the tissue of dry or hydrated seeds at all used ion energies. Therefore the entire energy was transferred to the treated tissue. Irradiated seeds were germinated vertically under dim light and roots growth was observed for two days after imbibition. The LD50 of the germination was about 2×1014 ions/cm2 and about 5×1014 ions/cm2 for imbibed and dry seeds, respectively. Since seedlings are most sensitive to gravity, the change in gravitropic behavior is a convenient means to assess radiation damage on physiological responses other than direct tissue damage. We compared curvature in untreated with irradiated roots and measured the inhibition of curvature at 2×1013 - 8×1013 ions/cm2. Despite greater mass of imbibed seeds, the dose-response curve showed greater sensitivity of imbibed than for dry seeds. In addition, germination rate was found to be strongly dependent on ion beam current, at least for 3 MeV protons. Our data show that weak ionizing particles (low MeV protons) are suitable to study radiation effects and seedlings are a useful biological systems to study space radiation. Supported by NASA grant NNX13AN05A.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Graves, E.
2015-06-15
Recent advances in cancer research have shed new light on the complex processes of how therapeutic radiation initiates changes at cellular, tissue, and system levels that may lead to clinical effects. These new advances may transform the way we use radiation to combat certain types of cancers. For the past two decades many technological advancements in radiation therapy have been largely based on the hypothesis that direct radiation-induced DNA double strand breaks cause cell death and thus tumor control and normal tissue damage. However, new insights have elucidated that in addition to causing cellular DNA damage, localized therapeutic radiation alsomore » initiates cascades of complex downstream biological responses in tissue that extend far beyond where therapeutic radiation dose is directly deposited. For instance, studies show that irradiated dying tumor cells release tumor antigens that can lead the immune system to a systemic anti-cancer attack throughout the body of cancer patient; targeted irradiation to solid tumor also increases the migration of tumor cells already in bloodstream, the seeds of potential metastasis. Some of the new insights may explain the long ago discovered but still unexplained non-localized radiation effects (bystander effect and abscopal effect) and the efficacy of spatially fractionated radiation therapy (microbeam radiation therapy and GRID therapy) where many “hot” and “cold” spots are intentionally created throughout the treatment volume. Better understanding of the mechanisms behind the non-localized radiation effects creates tremendous opportunities to develop new and integrated cancer treatment strategies that are based on radiotherapy, immunology, and chemotherapy. However, in the multidisciplinary effort to advance new radiobiology, there are also tremendous challenges including a lack of multidisciplinary researchers and imaging technologies for the microscopic radiation-induced responses. A better grasp of the essence of these advances in cancer biology research will give medical physicists a new perspective in daily clinical physics practice and in future radiation therapy technological development. Furthermore, academic medical physics should continue to be an integral part of the multidisciplinary cancer research community, harnessing our newly acquired understanding of radiation effects, and developing novel cost-effective treatment strategies to better combat cancer. Learning Objectives: Understand that localized radiation can lead to non-localized secondary effects such as radiation-induced immune response, bystander effect, and abscopal effect. Understand that the non-localized radiation effects may be harnessed to improve cancer treatment. Learn examples of physics participation in multidisciplinary research to advance cancer biology. Recognize the challenges and possibilities of physics applications in cancer research. Chang: NIH 5RC2CA148487-02 and 1U54CA151652-01 Graves: IDEA award (19IB-0106) from the California Breast Cancer Research Program (CBCRP), and by NIH P01 CA67166.« less
Indirect detection of radiation sources through direct detection of radiolysis products
Farmer, Joseph C [Tracy, CA; Fischer, Larry E [Los Gatos, CA; Felter, Thomas E [Livermore, CA
2010-04-20
A system for indirectly detecting a radiation source by directly detecting radiolytic products. The radiation source emits radiation and the radiation produces the radiolytic products. A fluid is positioned to receive the radiation from the radiation source. When the fluid is irradiated, radiolytic products are produced. By directly detecting the radiolytic products, the radiation source is detected.
Light-Cone Effect of Radiation Fields in Cosmological Radiative Transfer Simulations
NASA Astrophysics Data System (ADS)
Ahn, Kyungjin
2015-02-01
We present a novel method to implement time-delayed propagation of radiation fields in cosmo-logical radiative transfer simulations. Time-delayed propagation of radiation fields requires construction of retarded-time fields by tracking the location and lifetime of radiation sources along the corresponding light-cones. Cosmological radiative transfer simulations have, until now, ignored this "light-cone effect" or implemented ray-tracing methods that are computationally demanding. We show that radiative trans-fer calculation of the time-delayed fields can be easily achieved in numerical simulations when periodic boundary conditions are used, by calculating the time-discretized retarded-time Green's function using the Fast Fourier Transform (FFT) method and convolving it with the source distribution. We also present a direct application of this method to the long-range radiation field of Lyman-Werner band photons, which is important in the high-redshift astrophysics with first stars.
NASA Astrophysics Data System (ADS)
Thomas, Brian; Neale, Patrick
2016-01-01
Astrophysical ionizing radiation events have been recognized as a potential threat to life on Earth for decades. Although there is some direct biological damage on the surface from redistributed radiation several studies have indicated that the greatest long term threat is from ozone depletion and subsequent heightened solar ultraviolet (UV) radiation. It is known that organisms exposed to this irradiation experience harmful effects such as sunburn and even direct damage to DNA, proteins, or other cellular structures. Simulations of the atmospheric effects of a variety of events (such as supernovae, gamma-ray bursts, and solar proton events) have been previously published, along with estimates of biological damage at Earth's surface. In the present work, we employed a radiative transfer model to expand and improve calculations of surface-level irradiance and biological impacts following an ionizing radiation event. We considered changes in surface-level UVB, UVA, and photosynthetically active radiation (visible light). Using biological weighting functions we have considered a wide range of effects, including: erythema and skin cancer in humans; inhibition of photosynthesis in the diatom Phaeodactylum sp. and dinoflagellate Prorocentrum micans inhibition of carbon fixation in Antarctic phytoplankton; inhibition of growth of oat (Avena sativa L. cv. Otana) seedlings; and cataracts. We found that past work overestimated UVB irradiance, but that relative estimates for increase in exposure to DNA damaging radiation are still similar to our improved calculations. We also found that the intensity of biologically damaging radiation varies widely with organism and specific impact considered; these results have implications for biosphere-level damage following astrophysical ionizing radiation events. When considering changes in surface-level visible light irradiance, we found that, contrary to previous assumptions, a decrease in irradiance is only present for a short time in very limited geographical areas; instead we found a net increase for most of the modeled time-space region. This result has implications for proposed climate changes associated with ionizing radiation events.
Radiative Forcing Due to Major Aerosol Emitting Sectors in China and India
NASA Technical Reports Server (NTRS)
Streets, David G.; Shindell, Drew Todd; Lu, Zifeng; Faluvegi, Greg
2013-01-01
Understanding the radiative forcing caused by anthropogenic aerosol sources is essential for making effective emission control decisions to mitigate climate change. We examined the net direct plus indirect radiative forcing caused by carbonaceous aerosol and sulfur emissions in key sectors of China and India using the GISS-E2 chemistry-climate model. Diesel trucks and buses (67 mW/ sq. m) and residential biofuel combustion (52 mW/ sq. m) in India have the largest global mean, annual average forcings due mainly to the direct and indirect effects of BC. Emissions from these two sectors in China have near-zero net global forcings. Coal-fired power plants in both countries exert a negative forcing of about -30 mW/ sq. m from production of sulfate. Aerosol forcings are largest locally, with direct forcings due to residential biofuel combustion of 580 mW/ sq. m over India and 416 mW/ sq. m over China, but they extend as far as North America, Europe, and the Arctic
Modeling the Influences of Aerosols on Pre-Monsoon Circulation and Rainfall over Southeast Asia
NASA Technical Reports Server (NTRS)
Lee, D.; Sud, Y. C.; Oreopoulos, L.; Kim, K.-M.; Lau, W. K.; Kang, I.-S.
2014-01-01
We conduct several sets of simulations with a version of NASA's Goddard Earth Observing System, version 5, (GEOS-5) Atmospheric Global Climate Model (AGCM) equipped with a two-moment cloud microphysical scheme to understand the role of biomass burning aerosol (BBA) emissions in Southeast Asia (SEA) in the pre-monsoon period of February-May. Our experiments are designed so that both direct and indirect aerosol effects can be evaluated. For climatologically prescribed monthly sea surface temperatures, we conduct sets of model integrations with and without biomass burning emissions in the area of peak burning activity, and with direct aerosol radiative effects either active or inactive. Taking appropriate differences between AGCM experiment sets, we find that BBA affects liquid clouds in statistically significantly ways, increasing cloud droplet number concentrations, decreasing droplet effective radii (i.e., a classic aerosol indirect effect), and locally suppressing precipitation due to a deceleration of the autoconversion process, with the latter effect apparently also leading to cloud condensate increases. Geographical re-arrangements of precipitation patterns, with precipitation increases downwind of aerosol sources are also seen, most likely because of advection of weakly precipitating cloud fields. Somewhat unexpectedly, the change in cloud radiative effect (cloud forcing) at surface is in the direction of lesser cooling because of decreases in cloud fraction. Overall, however, because of direct radiative effect contributions, aerosols exert a net negative forcing at both the top of the atmosphere and, perhaps most importantly, the surface, where decreased evaporation triggers feedbacks that further reduce precipitation. Invoking the approximation that direct and indirect aerosol effects are additive, we estimate that the overall precipitation reduction is about 40% due to the direct effects of absorbing aerosols, which stabilize the atmosphere and reduce surface latent heat fluxes via cooler land surface temperatures. Further refinements of our two-moment cloud microphysics scheme are needed for a more complete examination of the role of aerosol-convection interactions in the seasonal development of the SEA monsoon.
Sawano, Toyoaki; Nishikawa, Yoshitaka; Ozaki, Akihiko; Leppold, Claire; Tsubokura, Masaharu
2018-05-01
The health threats of radiation-release incidents are diverse and long term. In addition to direct radiation effects, it is imperative to manage the indirect effects of radiation such as stigma, prejudice and broader mental health impacts. Six years after the Fukushima Daiichi Nuclear Power Plant accident of March 2011, bullying caused by stigma and prejudice toward evacuees, including children, has become a social problem in Japan. This phenomenon may be associated with the fact that knowledge about radiation has still not reached the general public, and to a potential lack of motivation among Japanese citizens to learn about radiation and bullying. Continuous and sustained education regarding radiation is warranted in order to enhance the general knowledge level about the effects of radiation in Japan after the Fukushima Daiichi Nuclear Power Plant accident, and this education will become an important reference for education after future nuclear disasters.
Sawano, Toyoaki; Nishikawa, Yoshitaka; Ozaki, Akihiko; Leppold, Claire; Tsubokura, Masaharu
2018-01-01
Abstract The health threats of radiation-release incidents are diverse and long term. In addition to direct radiation effects, it is imperative to manage the indirect effects of radiation such as stigma, prejudice and broader mental health impacts. Six years after the Fukushima Daiichi Nuclear Power Plant accident of March 2011, bullying caused by stigma and prejudice toward evacuees, including children, has become a social problem in Japan. This phenomenon may be associated with the fact that knowledge about radiation has still not reached the general public, and to a potential lack of motivation among Japanese citizens to learn about radiation and bullying. Continuous and sustained education regarding radiation is warranted in order to enhance the general knowledge level about the effects of radiation in Japan after the Fukushima Daiichi Nuclear Power Plant accident, and this education will become an important reference for education after future nuclear disasters. PMID:29635385
The Magnetic and Shielding Effects of Ring Current on Radiation Belt Dynamics
NASA Technical Reports Server (NTRS)
Fok, Mei-Ching
2012-01-01
The ring current plays many key roles in controlling magnetospheric dynamics. A well-known example is the magnetic depression produced by the ring current, which alters the drift paths of radiation belt electrons and may cause significant electron flux dropout. Little attention is paid to the ring current shielding effect on radiation belt dynamics. A recent simulation study that combines the Comprehensive Ring Current Model (CRCM) with the Radiation Belt Environment (RBE) model has revealed that the ring current-associated shielding field directly and/or indirectly weakens the relativistic electron flux increase during magnetic storms. In this talk, we will discuss how ring current magnetic field and electric shielding moderate the radiation belt enhancement.
NASA Astrophysics Data System (ADS)
Rajabi, Majid; Mojahed, Alireza
2016-11-01
In this paper, emergence of negative axial acoustic radiation force on a rigid oscillating spherical body is investigated for acoustic manipulation purposes. The problem of plane acoustic wave scattering from an oscillating spherical body submerged in an ideal acoustic fluid medium is solved. For the case of oscillating direction collinear with the wave propagation wave number vector (desired path), it has been shown that the acoustic radiation force, as a result of nonlinear acoustic wave interaction with bodies can be expressed as a linear function of incident wave field and the oscillation properties of the oscillator (i.e., amplitude and phase of oscillation). The negative (i.e., pulling effects) and positive (i.e., pushing effects) radiation force situations are divided in oscillation complex plane with a specific frequency-dependant straight line. This characteristic line defines the radiation force cancellation state. In order to investigate the stability of the mentioned manipulation strategy, the case of misaligned oscillation of sphere with the wave propagation direction is studied. The proposed methodology may suggest a novel concept of single-beam acoustic handling techniques based on smart carriers.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ahmed, M.
Recent advances in cancer research have shed new light on the complex processes of how therapeutic radiation initiates changes at cellular, tissue, and system levels that may lead to clinical effects. These new advances may transform the way we use radiation to combat certain types of cancers. For the past two decades many technological advancements in radiation therapy have been largely based on the hypothesis that direct radiation-induced DNA double strand breaks cause cell death and thus tumor control and normal tissue damage. However, new insights have elucidated that in addition to causing cellular DNA damage, localized therapeutic radiation alsomore » initiates cascades of complex downstream biological responses in tissue that extend far beyond where therapeutic radiation dose is directly deposited. For instance, studies show that irradiated dying tumor cells release tumor antigens that can lead the immune system to a systemic anti-cancer attack throughout the body of cancer patient; targeted irradiation to solid tumor also increases the migration of tumor cells already in bloodstream, the seeds of potential metastasis. Some of the new insights may explain the long ago discovered but still unexplained non-localized radiation effects (bystander effect and abscopal effect) and the efficacy of spatially fractionated radiation therapy (microbeam radiation therapy and GRID therapy) where many “hot” and “cold” spots are intentionally created throughout the treatment volume. Better understanding of the mechanisms behind the non-localized radiation effects creates tremendous opportunities to develop new and integrated cancer treatment strategies that are based on radiotherapy, immunology, and chemotherapy. However, in the multidisciplinary effort to advance new radiobiology, there are also tremendous challenges including a lack of multidisciplinary researchers and imaging technologies for the microscopic radiation-induced responses. A better grasp of the essence of these advances in cancer biology research will give medical physicists a new perspective in daily clinical physics practice and in future radiation therapy technological development. Furthermore, academic medical physics should continue to be an integral part of the multidisciplinary cancer research community, harnessing our newly acquired understanding of radiation effects, and developing novel cost-effective treatment strategies to better combat cancer. Learning Objectives: Understand that localized radiation can lead to non-localized secondary effects such as radiation-induced immune response, bystander effect, and abscopal effect. Understand that the non-localized radiation effects may be harnessed to improve cancer treatment. Learn examples of physics participation in multidisciplinary research to advance cancer biology. Recognize the challenges and possibilities of physics applications in cancer research. Chang: NIH 5RC2CA148487-02 and 1U54CA151652-01 Graves: IDEA award (19IB-0106) from the California Breast Cancer Research Program (CBCRP), and by NIH P01 CA67166.« less
NASA Astrophysics Data System (ADS)
Stier, P.; Schutgens, N. A. J.; Bian, H.; Boucher, O.; Chin, M.; Ghan, S.; Huneeus, N.; Kinne, S.; Lin, G.; Myhre, G.; Penner, J. E.; Randles, C.; Samset, B.; Schulz, M.; Yu, H.; Zhou, C.
2012-09-01
Simulated multi-model "diversity" in aerosol direct radiative forcing estimates is often perceived as measure of aerosol uncertainty. However, current models used for aerosol radiative forcing calculations vary considerably in model components relevant for forcing calculations and the associated "host-model uncertainties" are generally convoluted with the actual aerosol uncertainty. In this AeroCom Prescribed intercomparison study we systematically isolate and quantify host model uncertainties on aerosol forcing experiments through prescription of identical aerosol radiative properties in nine participating models. Even with prescribed aerosol radiative properties, simulated clear-sky and all-sky aerosol radiative forcings show significant diversity. For a purely scattering case with globally constant optical depth of 0.2, the global-mean all-sky top-of-atmosphere radiative forcing is -4.51 W m-2 and the inter-model standard deviation is 0.70 W m-2, corresponding to a relative standard deviation of 15%. For a case with partially absorbing aerosol with an aerosol optical depth of 0.2 and single scattering albedo of 0.8, the forcing changes to 1.26 W m-2, and the standard deviation increases to 1.21 W m-2, corresponding to a significant relative standard deviation of 96%. However, the top-of-atmosphere forcing variability owing to absorption is low, with relative standard deviations of 9% clear-sky and 12% all-sky. Scaling the forcing standard deviation for a purely scattering case to match the sulfate radiative forcing in the AeroCom Direct Effect experiment, demonstrates that host model uncertainties could explain about half of the overall sulfate forcing diversity of 0.13 W m-2 in the AeroCom Direct Radiative Effect experiment. Host model errors in aerosol radiative forcing are largest in regions of uncertain host model components, such as stratocumulus cloud decks or areas with poorly constrained surface albedos, such as sea ice. Our results demonstrate that host model uncertainties are an important component of aerosol forcing uncertainty that require further attention.
Mechanisms of poliovirus inactivation by the direct and indirect effects of ionizing radiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ward, R.L.
1980-08-01
This study was designed to measure the effects of ionizing radiation on poliovirus particles when given under conditions where either direct (in broth) or indirect (in water) effects were predominant. Under direct conditions, inactivation of poliovirus was found to be due primarily to RNA damage, although capsid damage could account for about one-third of the viral inactivation. RNA damage did not appear to be due to strand breakage and therefore was probably caused primarily by base damage or crosslink formation. Capsid damage under direct irradiation conditions did not result in significant alterations of either the sedimentation coefficients or the isoelectricmore » points of the poliovirus particles or detectable modification of the sizes of the viral proteins. It did, however, cause loss of availability to bind to host cells. Under indirect conditions no more than 25% of viral inactivation appeared to be due to RNA damage. However, the sedimentation coefficients and isoelectric points of the viral particles were greatly altered, and their abilities to bind to cells were lost at about three-fourths the rate of loss of infectivity. Capsid damage in this case did result in changes in the sizes of capsid proteins. Therefore, the majority of the radiation inactivation under indirect conditions appeared to be due to protein damage.« less
Parecoxib: an enhancer of radiation therapy for colorectal cancer.
Xiong, Wei; Li, Wen-Hui; Jiang, Yong-Xin; Liu, Shan; Ai, Yi-Qin; Liu, Rong; Chang, Li; Zhang, Ming; Wang, Xiao-Li; Bai, Han; Wang, Hong; Zheng, Rui; Tan, Jing
2015-01-01
To study the effect of parecoxib, a novel cyclooxygenase-2 selective inhibitor, on the radiation response of colorectal cancer (CRC) cells and its underlying mechanisms. Both in vitro colony formation and apoptosis assays as well as in vivo mouse xenograft experiments were used to explore the radiosensitizing effects of parecoxib in human HCT116 and HT29 CRC cells. Parecoxib sensitized CRC cells to radiation in vitro with a sensitivity enhancement ratio of 1.32 for HCT116 cells and 1.15 for HT29 cells at a surviving fraction of 0.37. This effect was partially attributable to enhanced apoptosis induction by parecoxib combined with radiation, as illustrated using an in vitro apoptosis assays. Parecoxib augmented the tumor response of HCT116 xenografts to radiation, achieving growth delay more than 20 days and an enhancement factor of 1.53. In accordance with the in vitro results, parecoxib combined with radiation resulted in less proliferation and more apoptosis in tumors than radiation alone. Radiation monotherapy decreased microvessel density (MVD) and microvessel intensity (MVI), but increased the hypoxia level in xenografts. Parecoxib did not affect MVD, but it increased MVI and attenuated hypoxia. Parecoxib can effectively enhance radiation sensitivity in CRC cells through direct effects on tumor cells and indirect effects on tumor vasculature.
Coates, Philip J; Rundle, Jana K; Lorimore, Sally A; Wright, Eric G
2008-01-15
In addition to the directly mutagenic effects of energy deposition in DNA, ionizing radiation is associated with a variety of untargeted and delayed effects that result in ongoing bone marrow damage. Delayed effects are genotype dependent with CBA/Ca mice, but not C57BL/6 mice, susceptible to the induction of damage and also radiation-induced acute myeloid leukemia. Because macrophages are a potential source of ongoing damaging signals, we have determined their gene expression profiles and we show that bone marrow-derived macrophages show widely different intrinsic expression patterns. The profiles classify macrophages derived from CBA/Ca mice as M1-like (pro-inflammatory) and those from C57BL/6 mice as M2-like (anti-inflammatory); measurements of NOS2 and arginase activity in normal bone marrow macrophages confirm these findings. After irradiation in vivo, but not in vitro, C57BL/6 macrophages show a reduction in NOS2 and an increase in arginase activities, indicating a further M2 response, whereas CBA/Ca macrophages retain an M1 phenotype. Activation of specific signal transducer and activator of transcription signaling pathways in irradiated hemopoietic tissues supports these observations. The data indicate that macrophage activation is not a direct effect of radiation but a tissue response, secondary to the initial radiation exposure, and have important implications for understanding genotype-dependent responses and the mechanisms of the hemotoxic and leukemogenic consequences of radiation exposure.
Radiation effects on the Gaia CCDs after 30 months at L2
NASA Astrophysics Data System (ADS)
Crowley, Cian; Abreu, Asier; Kohley, Ralf; Prod'homme, Thibaut; Beaufort, Thierry
2016-07-01
Since the launch of ESA's Gaia satellite in December 2013, the 106 large-format scientific CCDs onboard have been operating at L2. Due to a combination of the high-precision measurement requirements of the mission and the predicted proton environment at L2, the effect of non-ionizing radiation damage on the detectors was early identified pre-launch as potentially imposing a major limitation on the scientific value of the data. In this paper we compare pre-flight radiation-induced Charge Transfer Inefficiency (CTI) predictions against in-flight measurements, focusing especially on charge injection diagnostics, as well as correlating these CTI diagnostic results with solar proton event data. We show that L2-directed solar activity has been relatively low since launch, and radiation damage (so far) is less than originally expected. Despite this, there are clear cases of correlation between earth-directed solar coronal mass ejection events and abrupt changes in CTI diagnostics over time. These sudden jumps are lying on top of a rather constant increase in CTI which we show is primarily due to the continuous bombardment of the devices by high-energy Galactic Cosmic Rays. We examine the possible reasons for the lower than expected levels of CTI as well as examining the effect of controlled payload heating events on the CTI diagnostics. Radiation-induced CTI in the CCD serial registers and effects of ionizing radiation are also correspondingly lower than expected, however these topics are not examined here in detail.
NASA Astrophysics Data System (ADS)
Bates, T. S.; Anderson, T. L.; Baynard, T.; Bond, T.; Boucher, O.; Carmichael, G.; Clarke, A.; Erlick, C.; Guo, H.; Horowitz, L.; Howell, S.; Kulkarni, S.; Maring, H.; McComiskey, A.; Middlebrook, A.; Noone, K.; O'Dowd, C. D.; Ogren, J.; Penner, J.; Quinn, P. K.; Ravishankara, A. R.; Savoie, D. L.; Schwartz, S. E.; Shinozuka, Y.; Tang, Y.; Weber, R. J.; Wu, Y.
2006-05-01
The largest uncertainty in the radiative forcing of climate change over the industrial era is that due to aerosols, a substantial fraction of which is the uncertainty associated with scattering and absorption of shortwave (solar) radiation by anthropogenic aerosols in cloud-free conditions (IPCC, 2001). Quantifying and reducing the uncertainty in aerosol influences on climate is critical to understanding climate change over the industrial period and to improving predictions of future climate change for assumed emission scenarios. Measurements of aerosol properties during major field campaigns in several regions of the globe during the past decade are contributing to an enhanced understanding of atmospheric aerosols and their effects on light scattering and climate. The present study, which focuses on three regions downwind of major urban/population centers (North Indian Ocean (NIO) during INDOEX, the Northwest Pacific Ocean (NWP) during ACE-Asia, and the Northwest Atlantic Ocean (NWA) during ICARTT), incorporates understanding gained from field observations of aerosol distributions and properties into calculations of perturbations in radiative fluxes due to these aerosols. This study evaluates the current state of observations and of two chemical transport models (STEM and MOZART). Measurements of burdens, extinction optical depth (AOD), and direct radiative effect of aerosols (DRE - change in radiative flux due to total aerosols) are used as measurement-model check points to assess uncertainties. In-situ measured and remotely sensed aerosol properties for each region (mixing state, mass scattering efficiency, single scattering albedo, and angular scattering properties and their dependences on relative humidity) are used as input parameters to two radiative transfer models (GFDL and University of Michigan) to constrain estimates of aerosol radiative effects, with uncertainties in each step propagated through the analysis. Constraining the radiative transfer calculations by observational inputs increases the clear-sky, 24-h averaged AOD (34±8%), top of atmosphere (TOA) DRE (32±12%), and TOA direct climate forcing of aerosols (DCF - change in radiative flux due to anthropogenic aerosols) (37±7%) relative to values obtained with "a priori" parameterizations of aerosol loadings and properties (GFDL RTM). The resulting constrained clear-sky TOA DCF is -3.3±0.47, -14±2.6, -6.4±2.1 Wm-2 for the NIO, NWP, and NWA, respectively. With the use of constrained quantities (extensive and intensive parameters) the calculated uncertainty in DCF was 25% less than the "structural uncertainties" used in the IPCC-2001 global estimates of direct aerosol climate forcing. Such comparisons with observations and resultant reductions in uncertainties are essential for improving and developing confidence in climate model calculations incorporating aerosol forcing.
Effects of solar radiation pressure torque on the rotational motion of an artificial satellite
NASA Technical Reports Server (NTRS)
Zanardi, Maria Cecilia F. P. S.; Vilhenademoraes, Rodolpho
1992-01-01
The motion of an artificial satellite about its center of mass is studied considering torques due to the gravity gradient and direct solar radiation pressure. A model for direct solar radiation torque is derived for a circular cylindrical satellite. An analytical solution is obtained by the method of variation of the parameters. This solution shows that the angular variables have secular variation but that the modulus of the rotational angular momentum, the projection of rotational angular momentum on the z axis of the moment of inertia and inertial axis z, suffer only periodic variations. Considering a hypothetical artificial satellite, a numerical application is demonstrated.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kawamura, Yoshiyuki
The radiative forcing of the greenhouse gases has been studied being based on computational simulations or the observation of the real atmosphere meteorologically. In order to know the greenhouse effect more deeply and to study it from various viewpoints, the study on it in a laboratory scale is important. We have developed a direct measurement system for the infrared back radiation from the carbon dioxide (CO{sub 2}) gas. The system configuration is similar with that of the practical earth-atmosphere-space system. Using this system, the back radiation from the CO{sub 2} gas was directly measured in a laboratory scale, which roughlymore » coincides with meteorologically predicted value.« less
Bai, Xian-Ming
2014-10-23
I serve as a Guest Editor for the Nuclear Materials Committee of the TMS Structural Materials Division, and coordinated the topic ‘‘Radiation Effects in Oxide Ceramics and Novel LWR Fuels" for JOM in the December 2014 issue. I selected five articles related this topic. These articles talk about some recent progress of using advanced experimental and modeling tools to study radiation effects in oxide ceramics at atomistic scale and mesoscale. In this guest editor commentary article, I summarize the novel aspects of these papers and also provide some suggestions for future research directions.
NASA Astrophysics Data System (ADS)
Miller, W. F.; Kato, S.; Rose, F. G.; Sun-Mack, S.
2009-12-01
Under the NASA Energy and Water Cycle System (NEWS) program, cloud and aerosol properties derived from CALIPSO, CloudSat, and MODIS data then matched to the CERES footprint are used for irradiance profile computations. Irradiance profiles are included in the publicly available product, CCCM. In addition to the MODIS and CALIPSO generated aerosol, aerosol optical thickness is calculated over ocean by processing MODIS radiance through the Stowe-Ignatov algorithm. The CERES cloud mask and properties algorithm are use with MODIS radiance to provide additional cloud information to accompany the actively sensed data. The passively sensed data is the only input to the standard CERES radiative flux products. The combined information is used as input to the NASA Langley Fu-Liou radiative transfer model to determine vertical profiles and Top of Atmosphere shortwave and longwave flux for pristine, all-sky, and aerosol conditions for the special data product. In this study, the three sources of aerosol optical thickness will be compared directly and their influence on the calculated and measured TOA fluxes. Earlier studies indicate that the largest uncertainty in estimating direct aerosol forcing using aerosol optical thickness derived from passive sensors is caused by cloud contamination. With collocated CALIPSO data, we are able to estimate frequency of occurrence of cloud contamination, effect on the aerosol optical thickness and direct radiative effect estimates.
Beck, P; Latocha, M; Dorman, L; Pelliccioni, M; Rollet, S
2007-01-01
As required by the European Directive 96/29/Euratom, radiation exposure due to natural ionizing radiation has to be taken into account at workplaces if the effective dose could become more than 1 mSv per year. An example of workers concerned by this directive is aircraft crew due to cosmic radiation exposure in the atmosphere. Extensive measurement campaigns on board aircrafts have been carried out to assess ambient dose equivalent. A consortium of European dosimetry institutes within EURADOS WG5 summarized experimental data and results of calculations, together with detailed descriptions of the methods for measurements and calculations. The radiation protection quantity of interest is the effective dose, E (ISO). The comparison of results by measurements and calculations is done in terms of the operational quantity ambient dose equivalent, H(10). This paper gives an overview of the EURADOS Aircraft Crew In-Flight Database and it presents a new empirical model describing fitting functions for this data. Furthermore, it describes numerical simulations performed with the Monte Carlo code FLUKA-2005 using an updated version of the cosmic radiation primary spectra. The ratio between ambient dose equivalent and effective dose at commercial flight altitudes, calculated with FLUKA-2005, is discussed. Finally, it presents the aviation dosimetry model AVIDOS based on FLUKA-2005 simulations for routine dose assessment. The code has been developed by Austrian Research Centers (ARC) for the public usage (http://avidos.healthphysics.at).
How Models Simulate the Radiative Effect in the Transition Zone of the Aerosol-Cloud Continuum
NASA Astrophysics Data System (ADS)
Calbo Angrill, J.; González, J. A.; Long, C. N.; McComiskey, A. C.
2017-12-01
Several studies have pointed towards dealing with clouds and aerosols as two manifestations of what is essentially the same physical phenomenon: a suspension of tiny particles in the air. Although the two extreme cases (i.e., pure aerosol and well-defined cloud) are easily distinguished, and obviously produce different radiative effects, there are many situations in the transition (or "twilight") zone. In a recent paper [Calbó et al., Atmos. Res. 2017, j.atmosres.2017.06.010], the authors of the current communication estimated that about 10% of time there might be a suspension of particles in the air that is difficult to distinguish as either cloud or aerosol. Radiative transfer models, however, simulate the effect of clouds and aerosols with different modules, routines, or parameterizations. In this study, we apply a sensitivity analysis approach to assess the ability of two radiative transfer models (SBDART and RRTM) in simulating the radiative effect of a suspension of particles with characteristics in the boundary between cloud and aerosol. We simulate this kind of suspension either in "cloud mode" or in "aerosol mode" and setting different values of optical depth, droplet size, water path, aerosol type, cloud height, etc. Irradiances both for solar and infrared bands are studied, both at ground level and at the top of the atmosphere, and all analyses are repeated for different solar zenith angles. We obtain that (a) water clouds and ice clouds have similar radiative effects if they have the same optical depth; (b) the spread of effects regarding different aerosol type/aerosol characteristics is remarkable; (c) radiative effects of an aerosol layer and of a cloud layer are different, even if they have similar optical depth; (d) for a given effect on the diffuse component, the effect on the direct component is usually greater (more extinction of direct beam) by aerosols than by clouds; (e) radiative transfer models are somewhat limited when simulating the effects of a suspension of particles in the transition zone, as the approach to this zone as an aerosol or as a cloud produces different results.
A Green's Function Approach to Simulate DNA Damage by the Indirect Effect
NASA Technical Reports Server (NTRS)
Plante, Ianik; Cicinotta, Francis A.
2013-01-01
The DNA damage is of fundamental importance in the understanding of the effects of ionizing radiation. DNA is damaged by the direct effect of radiation (e.g. direct ionization) and by indirect effect (e.g. damage by.OH radicals created by the radiolysis of water). Despite years of research, many questions on the DNA damage by ionizing radiation remains. In the recent years, the Green's functions of the diffusion equation (GFDE) have been used extensively in biochemistry [1], notably to simulate biochemical networks in time and space [2]. In our future work on DNA damage, we wish to use an approach based on the GFDE to refine existing models on the indirect effect of ionizing radiation on DNA. To do so, we will use the code RITRACKS [3] developed at the NASA Johnson Space Center to simulate the radiation track structure and calculate the position of radiolytic species after irradiation. We have also recently developed an efficient Monte-Carlo sampling algorithm for the GFDE of reversible reactions with an intermediate state [4], which can be modified and adapted to simulate DNA damage by free radicals. To do so, we will use the known reaction rate constants between radicals (OH, eaq, H,...) and the DNA bases, sugars and phosphates and use the sampling algorithms to simulate the diffusion of free radicals and chemical reactions with DNA. These techniques should help the understanding of the contribution of the indirect effect in the formation of DNA damage and double-strand breaks.
Host Model Uncertainty in Aerosol Radiative Forcing Estimates - The AeroCom Prescribed Experiment
NASA Astrophysics Data System (ADS)
Stier, P.; Kinne, S.; Bellouin, N.; Myhre, G.; Takemura, T.; Yu, H.; Randles, C.; Chung, C. E.
2012-04-01
Anthropogenic and natural aerosol radiative effects are recognized to affect global and regional climate. However, even for the case of identical aerosol emissions, the simulated direct aerosol radiative forcings show significant diversity among the AeroCom models (Schulz et al., 2006). Our analysis of aerosol absorption in the AeroCom models indicates a larger diversity in the translation from given aerosol radiative properties (absorption optical depth) to actual atmospheric absorption than in the translation of a given atmospheric burden of black carbon to the radiative properties (absorption optical depth). The large diversity is caused by differences in the simulated cloud fields, radiative transfer, the relative vertical distribution of aerosols and clouds, and the effective surface albedo. This indicates that differences in host model (GCM or CTM hosting the aerosol module) parameterizations contribute significantly to the simulated diversity of aerosol radiative forcing. The magnitude of these host model effects in global aerosol model and satellites retrieved aerosol radiative forcing estimates cannot be estimated from the diagnostics of the "standard" AeroCom forcing experiments. To quantify the contribution of differences in the host models to the simulated aerosol radiative forcing and absorption we conduct the AeroCom Prescribed experiment, a simple aerosol model and satellite retrieval intercomparison with prescribed highly idealised aerosol fields. Quality checks, such as diagnostic output of the 3D aerosol fields as implemented in each model, ensure the comparability of the aerosol implementation in the participating models. The simulated forcing variability among the models and retrievals is a direct measure of the contribution of host model assumptions to the uncertainty in the assessment of the aerosol radiative effects. We will present the results from the AeroCom prescribed experiment with focus on the attribution to the simulated variability to parametric and structural model uncertainties. This work will help to prioritise areas for future model improvements and ultimately lead to uncertainty reduction.
Fine alignment of a large segmented mirror
NASA Technical Reports Server (NTRS)
Dey, Thomas William (Inventor)
2010-01-01
A system for aligning a segmented mirror includes a source of radiation directed along a first axis to the segmented mirror and a beamsplitter removably inserted along the first axis for redirecting radiation from the first axis to a second axis, substantially perpendicular to the first axis. An imaging array is positioned along the second axis for imaging the redirected radiation, and a knife-edge configured for cutting the redirected radiation is serially positioned to occlude and not occlude the redirected radiation, effectively providing a variable radiation pattern detected by the imaging array for aligning the segmented mirror.
Brodecki, Marcin; Domienik, Joanna U; Zmyślony, Marek
2012-01-01
The current system of dosimetric quantities has been defined by the International Commission on Radiological Protection (ICRP) and the International Commission on Radiation Units and Measurements (ICRU). Complexity of the system implies the physical nature of ionizing radiation, resulting from the presence of different types of radiation of different ionization capabilities, as well as the individual radiation sensitivity of biological material exposed. According to the latest recommendations, there are three types of dosimeter quantities relevant to radiation protection and radiological assessment of occupational exposure. These are the basic quantities, safety quantities and operational quantities. Dose limits for occupational exposure relate directly to the protection quantities, i.e. the equivalent dose and effective dose, while these quantities are practically unmeasurable in real measurement conditions. For this reason, in the system of dosimetric quantities directly measurable operating volumes were defined. They represent equivalents of the protection quantities that allow for a reliable assessment of equivalent and effective dose by conducting routine monitoring of occupational exposure. This paper presents the characteristics of these quantities, their relationships and importance in assessing individual effects of radiation. Also the methods for their implementation in personal and environmental dosimetry were showcased. The material contained in the article is a compendium of essential information about dosimetric quantities with reference to the contemporary requirements of the law, including the changed annual occupational exposure limit for the lens of the eye. The material is especially addressed to those responsible for dosimetry monitoring in the workplace, radiation protection inspectors and occupational health physicians.
Lee, Yu-San; Kao, Yu-Hsiu
2016-08-01
The skin reaction rate is 60-95% in cancer patients that receive radiation therapy. This therapy is likely to cause physical and mental discomfort and prolong treatment for patients. The current emphasis on lectures rather than practice to help nurses learn proper skin care practices likely imposes difficulties for nurses to handle various clinical situations. To investigate the learning effectiveness of a simulated radiation therapy skin care workshop for nurses. A total of 34 nurses at a hospital in one health system in northern Taiwan who had never used radiation therapy to provide care to patients were enrolled in this quasi-experimental study. A single group pretest, posttest and post-posttest (6 weeks after intervention) approach was used. At the simulated radiation therapy skin care workshop, we used teaching strategies including Ausubel's direct instruction teaching method and practice on simulated wounds on pig skins. Outcomes were evaluated using "the questionnaire of radiation therapy skin care" and "direct observation of procedural skills checklist". The results from the simulated radiation therapy skin care workshop were analyzed using GEE (generalized estimating equation). The post-posttest and posttest scores increased significantly; knowledge mean score 3.14 (< .001) vs 2.64 (< .001), attitude mean score 2.06 (p < .05) vs 2.24 (p < .001), and skill mean score 2.79 (p < .001) vs 1.68 (p < .001). The simulated radiation therapy skin care workshop demonstrated significant and positive effects on learning outcomes. Therefore, we recommend incorporating this workshop into clinical nursing education and training strategies in the future.
Solar radiation for Mars power systems
NASA Technical Reports Server (NTRS)
Appelbaum, Joseph; Landis, Geoffrey A.
1991-01-01
Detailed information about the solar radiation characteristics on Mars are necessary for effective design of future planned solar energy systems operating on the surface of Mars. A procedure and solar radiation related data from which the diurnally and daily variation of the global, direct (or beam), and diffuse insolation on Mars are calculated, are presented. The radiation data are based on measured optical depth of the Martian atmosphere derived from images taken of the Sun with a special diode on the Viking Lander cameras; and computation based on multiple wavelength and multiple scattering of the solar radiation.
NASA Technical Reports Server (NTRS)
Appelbaum, Joseph; Flood, Dennis J.
1989-01-01
Detailed information on solar radiation characteristics on Mars are necessary for effective design of future planned solar energy systems operating on the surface of Mars. Presented here is a procedure and solar radiation related data from which the diurnally, hourly and daily variation of the global, direct beam and diffuse insolation on Mars are calculated. The radiation data are based on measured optical depth of the Martian atmosphere derived from images taken of the sun with a special diode on the Viking cameras; and computation based on multiple wavelength and multiple scattering of the solar radiation.
NASA Technical Reports Server (NTRS)
Appelbaum, Joseph; Flood, Dennis J.
1990-01-01
Detailed information on solar radiation characteristics on Mars are necessary for effective design of future planned solar energy systems operating on the surface of Mars. Presented here is a procedure and solar radiation related data from which the diurnally, hourly and daily variation of the global, direct beam and diffuse insolation on Mars are calculated. The radiation data are based on measured optical depth of the Martian atmosphere derived from images taken of the sun with a special diode on the Viking cameras; and computation based on multiple wavelength and multiple scattering of the solar radiation.
NASA Technical Reports Server (NTRS)
Plante, Ianik; Cucinotta, Francis A.
2010-01-01
Heavy ions have gained considerable importance in radiotherapy due to their advantageous dose distribution profile and high Relative Biological Effectiveness (RBE). Heavy ions are difficult to produce on Earth, but they are present in space and it is impossible at this moment to completely shield astronauts from them. The risk of these radiations is poorly understood, which is a concern for a 3-years Mars mission. The effects of radiation are mainly due to DNA damage such as DNA double-strand breaks (DSBs), although non-targeted effects are also very important. DNA can be damaged by the direct interaction of radiation and by reactions with chemical species produced by the radiolysis of water. The energy deposition is of crucial importance to understand biological effects of radiation. Therefore, much effort has been done recently to improve models of radiation tracks.
Hasegawa, Arifumi; Tanigawa, Koichi; Ohtsuru, Akira; Yabe, Hirooki; Maeda, Masaharu; Shigemura, Jun; Ohira, Tetsuya; Tominaga, Takako; Akashi, Makoto; Hirohashi, Nobuyuki; Ishikawa, Tetsuo; Kamiya, Kenji; Shibuya, Kenji; Yamashita, Shunichi; Chhem, Rethy K
2015-08-01
437 nuclear power plants are in operation at present around the world to meet increasing energy demands. Unfortunately, five major nuclear accidents have occurred in the past--ie, at Kyshtym (Russia [then USSR], 1957), Windscale Piles (UK, 1957), Three Mile Island (USA, 1979), Chernobyl (Ukraine [then USSR], 1986), and Fukushima (Japan, 2011). The effects of these accidents on individuals and societies are diverse and enduring. Accumulated evidence about radiation health effects on atomic bomb survivors and other radiation-exposed people has formed the basis for national and international regulations about radiation protection. However, past experiences suggest that common issues were not necessarily physical health problems directly attributable to radiation exposure, but rather psychological and social effects. Additionally, evacuation and long-term displacement created severe health-care problems for the most vulnerable people, such as hospital inpatients and elderly people. Copyright © 2015 Elsevier Ltd. All rights reserved.
NASA Technical Reports Server (NTRS)
Theriot, Corey A.; Gersey, Buddy; Bacon, Eugene; Johnson, Quincy; Zhang, Ye; Norman, Jullian; Foley, Ijette; Wilkins, Rick; Zhou, Jianren; Wu, Honglu
2010-01-01
NASA has an extensive program for studying materials and methods for the shielding of astronauts to reduce the effects of space radiation when on the surfaces of the Moon and Mars, especially in the use of in situ materials native to the destination reducing the expense of materials transport. The most studied material from the Moon is Lunar regolith and has been shown to be as efficient as aluminum for shielding purposes (1). The addition of hydrogenous materials such as polyethylene should increase shielding effectiveness and provide mechanical properties necessary of structural materials (2). The neutron radiation shielding effectiveness of polyethylene/regolith stimulant (JSC-1A) composites were studied using confluent human fibroblast cell cultures exposed to a beam of high-energy spallation neutrons at the 30deg-left beam line (ICE house) at the Los Alamos Neutron Science Center. At this angle, the radiation spectrum mimics the energy spectrum of secondary neutrons generated in the upper atmosphere and encountered when aboard spacecraft and high-altitude aircraft. Cell samples were exposed in series either directly to the neutron beam, within a habitat created using regolith composite blocks, or behind 25 g/sq cm of loose regolith bulk material. In another experiment, cells were also exposed in series directly to the neutron beam in T-25 flasks completely filled with either media or water up to a depth of 20 cm to test shielding effectiveness versus depth and investigate the possible influence of secondary particle generation. All samples were sent directly back to JSC for sub-culturing and micronucleus analysis. This presentation is of work performed in collaboration with the NASA sponsored Center for Radiation Engineering and Science for Space Exploration (CRESSE) at Prairie View A&M.
Nakashima, Eiji; Neriishi, Kazuo; Hsu, Wan-Ling
2015-01-01
For youngmore » atomic-bomb (A-bomb) survivors, A-bomb radiation’s (total) effect on standing height is thought to comprise the sum of direct effect and indirect effect via inflammation. With the data of five inflammatory markers—white blood cell count, sialic acid, corrected erythrocyte sedimentation rate (ESR), α 1 globulin, and α 2 globulin—obtained in adulthood during the period 1988 to 1992, a summary inflammatory index was constructed as a surrogate for the five subclinical inflammatory markers. For 3,327 A-bomb survivors exposed at ages of less than 25 years, a structural equation model was analyzed to measure direct radiation effects on adult height as well as mediating effect of radiation via inflammation on the height after adjustment for other risk factors, smoking, cancer, inflammatory disease, obesity, and diabetes mellitus. The mediation proportion of the radiation effect on height via inflammation was approximately 5% for both sexes for all ages, and indirect dose effects via inflammation were statistically significant for both sexes combined and for females exposed at ages 0 to 5 years. Indirect dose effects for all ages via sialic acid, corrected ESR, and α 2 globulin were marginally significant for both sexes combined and for females. These proportions are likely underestimated.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nakashima, Eiji; Neriishi, Kazuo; Hsu, Wan-Ling
For youngmore » atomic-bomb (A-bomb) survivors, A-bomb radiation’s (total) effect on standing height is thought to comprise the sum of direct effect and indirect effect via inflammation. With the data of five inflammatory markers—white blood cell count, sialic acid, corrected erythrocyte sedimentation rate (ESR), α 1 globulin, and α 2 globulin—obtained in adulthood during the period 1988 to 1992, a summary inflammatory index was constructed as a surrogate for the five subclinical inflammatory markers. For 3,327 A-bomb survivors exposed at ages of less than 25 years, a structural equation model was analyzed to measure direct radiation effects on adult height as well as mediating effect of radiation via inflammation on the height after adjustment for other risk factors, smoking, cancer, inflammatory disease, obesity, and diabetes mellitus. The mediation proportion of the radiation effect on height via inflammation was approximately 5% for both sexes for all ages, and indirect dose effects via inflammation were statistically significant for both sexes combined and for females exposed at ages 0 to 5 years. Indirect dose effects for all ages via sialic acid, corrected ESR, and α 2 globulin were marginally significant for both sexes combined and for females. These proportions are likely underestimated.« less
Spatial Variation In Growing Season Heat Sums Within Northern Hardwood Forest Canopy Gaps
Brian E. Potter; Paul J. Croft
2000-01-01
When a gap forms in a forest canopy, the first and most immediate effect on the exposed area is an increase in radiative exchange near the ground. More sunlight reaches the ground during the daytime, and at nighttime the ground is more exposed to longwave radiation influences from the sky. These changes in radiation lead directly to a different near-ground temperature...
Local effects of partly cloudy skies on solar and emitted radiations
NASA Technical Reports Server (NTRS)
Whitney, D. A.; Venable, D. D.
1981-01-01
Solar radiation measurements are made on a routine basis. Global solar, atmospheric emitted, downwelled diffuse solar, and direct solar radiation measurement systems are fully operational with the first two in continuous operation. Fractional cloud cover measurements are made from GOES imagery or from ground based whole sky photographs. Normalized global solar irradiance values for partly cloudy skies were correlated to fractional cloud cover.
The 3D Radiation Dose Analysis For Satellite
NASA Astrophysics Data System (ADS)
Cai, Zhenbo; Lin, Guocheng; Chen, Guozhen; Liu, Xia
2002-01-01
the earth. These particles come from the Van Allen Belt, Solar Cosmic Ray and Galaxy Cosmic Ray. They have different energy and flux, varying with time and space, and correlating with solar activity tightly. These particles interact with electrical components and materials used on satellites, producing various space radiation effects, which will damage satellite to some extent, or even affect its safety. orbit. Space energy particles inject into components and materials used on satellites, and generate radiation dose by depositing partial or entire energy in them through ionization, which causes their characteristic degradation or even failure. As a consequence, the analysis and protection for radiation dose has been paid more attention during satellite design and manufacture. Designers of satellites need to analyze accurately the space radiation dose while satellites are on orbit, and use the results as the basis for radiation protection designs and ground experiments for satellites. can be calculated, using the model of the trapped proton and the trapped electron in the Van Allen Belt (AE8 and AP8). This is the 1D radiation dose analysis for satellites. Obviously, the mass shielding from the outside space to the computed point in all directions is regarded as a simple sphere shell. The actual structure of satellites, however, is very complex. When energy particles are injecting into a given equipment inside satellite from outside space, they will travel across satellite structure, other equipment, the shell of the given equipment, and so on, which depends greatly on actual layout of satellite. This complex radiation shielding has two characteristics. One is that the shielding masses for the computed point are different in different injecting directions. The other is that for different computed points, the shielding conditions vary in all space directions. Therefore, it is very difficult to tell the differences described above using the 1D radiation analysis, and hence, it is too simple to guide satellite radiation protection and ground experiments only based on the 1D radiation analysis results. To comprehend the radiation dose status of satellite adequately, it's essential to perform 3D radiation analysis for satellites. using computer software. From this 3D layout, the satellite model can be simplified appropriately. First select the point to be analyzed in the simplified satellite model, and extend many lines to the outside space, which divides the 4 space into many corresponding small areas with a certain solid angle. Then the shielding masses through the satellite equipment and structures along each direction are calculated, resulting in the shielding mass distribution in all space directions based on the satellite layout. Finally, using the relationship between radiation dose and shielding thickness from the 1D analysis, calculate the radiation dose in each area represented by each line. After we obtain the radiation dose and its space distribution for the point of interest, the 3D satellite radiation analysis is completed. radiation analysis based on satellite 3D CAD layout has larger benefit for engineering applications than the 1D analysis based on the solid sphere shielding model. With the 3D model, the analysis of space environment and its effect is combined closely with actual satellite engineering. The 3D radiation analysis not only provides valuable engineering data for satellite radiation design and protection, but also provides possibility to apply new radiation protection approaches, which expands technology horizon and broadens ways for technology development.
On the radiative effects of light-absorbing impurities on snowpack evolution
NASA Astrophysics Data System (ADS)
Dumont, M.; Tuzet, F.; Lafaysse, M.; Arnaud, L.; Picard, G.; Lejeune, Y.; Lamare, M.; Morin, S.; Voisin, D.; Di Mauro, B.
2017-12-01
The presence of light absorbing impurities in snow strongly decreases snow reflectance leading to an increase in the amount of solar energy absorbed by the snowpack. This effect is also known as impurities direct radiative effect. The change in the amount of energy absorbed by the snowpack modifies the temperature profile inside the snowpack and in turn snow metamorphism (impurities indirect radiative effects). In this work, we used the detailed snowpack model SURFEX/ISBA-Crocus with an explicit representation of snow light-absorbing impurities content (Tuzet et al., 2017) fed by medium-resolution ALADIN-Climate atmospheric model to represent dust and black carbon atmospheric deposition fluxes. The model is used at two sites: Col de Porte (medium elevation site in the French Alps) and Torgnon (high elevation site in the Italian Alps). The simulations are compared to in-situ observations and used to quantify the effects of light-absorbing impurities on snow melt rate and timing. The respective parts of the direct and indirect radiative effects of light-absorbing impurities in snow are also computed for the two sites, emphasizing the need to account for the interactions between snow metamorphism and LAI radiative properties, to accurately predict the effects of light-absorbing impurities in snow. Moreover, we describe how automated hyperspectral reflectance can be used to estimate effective impurities surface content in snow. Finally we demonstrate how these reflectances measurements either from in situ or satellite data can be used via an assimilation scheme to constrain snowpack ensemble simulations and better predict the snowpack state and evolution.
Semsarha, Farid; Raisali, Gholamreza; Goliaei, Bahram; Khalafi, Hossein
2016-05-01
In order to obtain the energy deposition pattern of ionizing radiation in the nanometric scale of genetic material and to investigate the different sensitivities of the DNA conformations, direct effects of (60)Co gamma rays on the three A, B and Z conformations of DNA have been studied. For this purpose, single-strand breaks (SSB), double-strand breaks (DSB), base damage (BD), hit probabilities and three microdosimetry quantities (imparted energy, mean chord length and lineal energy) in the mentioned DNA conformations have been calculated and compared by using GEometry ANd Tracking 4 (Geant4) toolkit. The results show that A-, B- and Z-DNA conformations have the highest yields of DSB (1.2 Gy(-1) Gbp(-1)), SSB (25.2 Gy(-1) Gbp(-1)) and BD (4.81 Gy(-1) Gbp(-1)), respectively. Based on the investigation of direct effects of radiation, it can be concluded that the DSB yield is largely correlated to the topological characteristics of DNA models, although the SSB yield is not. Moreover, according to the comparative results of the present study, a reliable candidate parameter for describing the relationship between DNA damage yields and geometry of DNA models in the theoretical radiation biology research studies would be the mean chord length (4 V/S) of the models.
Assessment of the effects of environmental radiation on wind chill equivalent temperatures.
Shitzer, Avraham
2008-09-01
Combinations of wind-driven convection and environmental radiation in cold weather, make the environment "feel" colder. The relative contributions of these mechanisms, which form the basis for estimating wind chill equivalent temperatures (WCETs), are studied over a wide range of environmental conditions. Distinction is made between direct solar radiation and environmental radiation. Solar radiation, which is not included in the analysis, has beneficial effects, as it counters and offsets some of the effects due to wind and low air temperatures. Environmental radiation effects, which are included, have detrimental effects in enhancing heat loss from the human body, thus affecting the overall thermal sensation due to the environment. The analysis is performed by a simple, steady-state analytical model of human-environment thermal interaction using upper and lower bounds of environmental radiation heat exchange. It is shown that, over a wide range of relevant air temperatures and reported wind speeds, convection heat losses dominate over environmental radiation. At low wind speeds radiation contributes up to about 23% of the overall heat loss from exposed skin areas. Its relative contributions reduce considerably as the time of the exposure prolongs and exposed skin temperatures drop. At still higher wind speeds, environmental radiation effects become much smaller contributing about 5% of the total heat loss. These values fall well within the uncertainties associated with the parameter values assumed in the computation of WCETs. It is also shown that environmental radiation effects may be accommodated by adjusting reported wind speeds slightly above their reported values.
Long-term biological effects induced by ionizing radiation--implications for dose mediated risk.
Miron, S D; Astărăstoae, V
2014-01-01
Ionizing radiations are considered to be risk agents that are responsible for the effects on interaction with living matter. The occurring biological effects are due to various factors such as: dose, type of radiation, exposure time, type of biological tissue, health condition and the age of the person exposed. The mechanisms involved in the direct modifications of nuclear DNA and mitochondrial DNA are reviewed. Classical target theory of energy deposition in the nucleus that causes DNA damages, in particular DNA double-strand breaks and that explanation of the biological consequences of ionizing radiation exposure is a paradigm in radiobiology. Recent experimental evidences have demonstrated the existence of a molecular mechanism that explains the non-targeted effects of ionizing radiation exposure. Among these novel data, genomic instability and a variety of bystander effects are discussed here. Those bystander effects of ionizing radiation are fulfilled by cellular communication systems that give rise to non-targeted effects in the neighboring non irradiated cells. This paper provides also a commentary on the synergistic effects induced by the co-exposures to ionizing radiation and various physical agents such as electromagnetic fields and the co-exposures to ionizing radiation and chemical environmental contaminants such as metals. The biological effects of multiple stressors on genomic instability and bystander effects are also discussed. Moreover, a brief presentation of the methods used to characterize cyto- and genotoxic damages is offered.
A New Fast Algorithm to Completely Account for Non-Lambertian Surface Reflection of The Earth
NASA Technical Reports Server (NTRS)
Qin, Wen-Han; Herman, Jay R.; Ahmad, Ziauddin; Einaudi, Franco (Technical Monitor)
2000-01-01
Surface bidirectional reflectance distribution function (BRDF) influences not only radiance just about the surface, but that emerging from the top of the atmosphere (TOA). In this study we propose a new, fast and accurate, algorithm CASBIR (correction for anisotropic surface bidirectional reflection) to account for such influences on radiance measured above TOA. This new algorithm is based on a 4-stream theory that separates the radiation field into direct and diffuse components in both upwelling and downwelling directions. This is important because the direct component accounts for a substantial portion of incident radiation under a clear sky, and the BRDF effect is strongest in the reflection of the direct radiation reaching the surface. The model is validated by comparison with a full-scale, vector radiation transfer model for the atmosphere-surface system. The result demonstrates that CASBIR performs very well (with overall relative difference of less than one percent) for all solar and viewing zenith and azimuth angles considered in wavelengths from ultraviolet to near-infrared over three typical, but very different surface types. Application of this algorithm includes both accounting for non-Lambertian surface scattering on the emergent radiation above TOA and a potential approach for surface BRDF retrieval from satellite measured radiance.
"Investigation of Trends in Aerosol Direct Radiative Effects ...
While aerosol radiative effects have been recognized as some of the largest sources of uncertainty among the forcers of climate change, there has been little effort devoted to verification of the spatial and temporal variability of the magnitude and directionality of aerosol radiative forcing. A comprehensive investigation of the processes regulating aerosol distributions, their optical properties, and their radiative effects and verification of their simulated effects for past conditions relative to measurements is needed in order to build confidence in the estimates of the projected impacts arising from changes in both anthropogenic forcing and climate change. This study aims at addressing this issue through a systematic investigation of changes in anthropogenic emissions of SO2 and NOx over the past two decades in the United States, their impacts on anthropogenic aerosol loading in the North American troposphere, and subsequent impacts on regional radiation budgets. During the period 1990-2010, SO2 and NOx emissions across the US have reduced by about 66% and 50%, respectively, mainly due to Title IV of the U.S. Clean Air Act Amendments (CAA). A methodology is developed to consistently estimate emission inventories for the 20-year period accounting for air quality regulations as well as population trends, economic conditions, and technology changes in motor vehicles and electric power generation. The coupled WRF-CMAQ model is applied for time periods pre a
Health effects of prenatal radiation exposure.
Williams, Pamela M; Fletcher, Stacy
2010-09-01
Pregnant women are at risk of exposure to nonionizing and ionizing radiation resulting from necessary medical procedures, workplace exposure, and diagnostic or therapeutic interventions before the pregnancy is known. Nonionizing radiation includes microwave, ultrasound, radio frequency, and electromagnetic waves. In utero exposure to nonionizing radiation is not associated with significant risks; therefore, ultrasonography is safe to perform during pregnancy. Ionizing radiation includes particles and electromagnetic radiation (e.g., gamma rays, x-rays). In utero exposure to ionizing radiation can be teratogenic, carcinogenic, or mutagenic. The effects are directly related to the level of exposure and stage of fetal development. The fetus is most susceptible to radiation during organogenesis (two to seven weeks after conception) and in the early fetal period (eight to 15 weeks after conception). Noncancer health effects have not been detected at any stage of gestation after exposure to ionizing radiation of less than 0.05 Gy (5 rad). Spontaneous abortion, growth restriction, and mental retardation may occur at higher exposure levels. The risk of cancer is increased regardless of the dose. When an exposure to ionizing radiation occurs, the total fetal radiation dose should be estimated and the mother counseled about the potential risks so that she can make informed decisions about her pregnancy management.
Radiated noise characteristics of a modern cargo ship
Arveson; Vendittis
2000-01-01
Extensive measurements were made of the radiated noise of M/V OVERSEAS HARRIETTE, a bulk cargo ship (length 173 m, displacement 25 515 tons) powered by a direct-drive low-speed diesel engine-a design representative of many modern merchant ships. The radiated noise data show high-level tonal frequencies from the ship's service diesel generator, main engine firing rate, and blade rate harmonics due to propeller cavitation. Radiated noise directionality measurements indicate that the radiation is generally dipole in form at lower frequencies, as expected. There are some departures from this pattern that may indicate hull interactions. Blade rate source level (174 dB re 1 microPa/m at 9 Hz, 16 knots) agrees reasonably well with a model of fundamental blade rate radiation previously reported by Gray and Greeley, but agreement for blade rate harmonics is not as good. Noise from merchant ships elevates the natural ambient by 20-30 dB in many areas; the effects of this noise on the biological environment have not been widely investigated.
Weaver, Charles L; Schott, Robert J; Prelas, Mark A; Wisniewski, Denis A; Rothenberger, Jason B; Lukosi, Eric D; Oh, Kyuhak
2018-02-01
Radiation damage is a significant concern with both alphavoltaic and betavoltaic cells because their performance degrades, especially with high-energy - (>200keV) beta and alpha particles. Indirect excitation methods, such as the Photon Intermediate Direct Energy Conversion (PIDEC) framework, can protect the transducer from radiation. A nuclear battery using a 90 Sr beta source was constructed by the author's research group, which demonstrated the radiation resistance of a PIDEC cell driven by beta particles (PIDECβ cell). Use of alpha sources to drive nuclear batteries would appear to be much more attractive than beta sources due to higher potential power density. However, they are also subject to higher rates of radiation damage. This paper describes the successful incorporation of alpha particles into the PIDEC framework using the alpha emitter 210 Po to form a PIDECα cell. The PIDECα cell transducer was exposed to alpha particles for over one year without experiencing adverse effects from radiation damage. Copyright © 2017 Elsevier Ltd. All rights reserved.
In vitro fertilization of mouse ova by spermatozoa exposed isothermally to radio-frequency radiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cleary, S.F.; Liu, L.M.; Graham, R.
Mouse spermatozoa were exposed in vitro for 1 h to 27- or 2,450-MHz CW RF radiation at SARs of 0 to 90 W/kg under isothermal (37 +/- 0.2 degrees C) conditions. Exposure at either frequency to RF radiation at SARs of 50 W/kg or greater resulted in a statistically significant reduction in the ability of irradiated sperm to fertilize mouse ova in vitro (P less than .05). Over the range of SARs there was no apparent difference in the effects of 27- vs. 2,450-MHz RF radiation. There were no readily detectable exposure effects on spermatozoan morphology, ultrastructure, or capacitation. Themore » reduction of in vitro fertilization is attributed to a direct effect of RF radiation on spermatozoa rather than to heating.« less
CLouds, and Aerosols Radiative Impacts and Forcing: Year 2016 (CLARIFY-2016)
NASA Astrophysics Data System (ADS)
Haywood, J. M.; Bellouin, N.; Carslaw, K. S.; Coe, H.; Field, P.; Highwood, E. J.; Redemann, J.; Stier, P.; Wood, R.; Zuidema, P.
2013-12-01
Strongly absorbing biomass burning aerosols (BBAs) exist above highly reflectant stratocumulus clouds in the SE Atlantic with implications on the direct (e.g. Haywood et al., 2003), semi-direct (e.g. Johnson et al., 2006), and indirect effect of aerosols, implications on the remote sensing of cloud optical properties, development of clouds and feedback processes. Here, we present an analysis of modelled estimates of the direct effect using twelve models from the AEROCOM project (Myhre et al., 2013) to show that estimates of the direct effect in SE Atlantic range from strongly negative to strongly positive. Furthermore, we evaluate the performance of the HadGEM2 model and show it cannot replicate the extreme values of positive forcing inferred from high spectral resolution satellite retrievals. By examining patterns of deposition, we infer that the indirect effect from biomass burning aerosols is very limited in the model, but without detailed measurements we are unsure of the validity of this inference. We conclude that the SE Atlantic is therefore of key importance in determining the radiative forcing of biomass burning aerosols and provides a very stringent test for global climate models as they need to accurately represent the geographic distribution of the aerosol optical depth, the wavelength dependent aerosol single scattering albedo, the vertical profile of the aerosol, the geographic distribution of the cloud, the cloud fraction, the cloud liquid water content, the cloud droplet effective radii, and the vertical profile of the cloud. These results are used as scientific rationale to justify a new measurement campaign: CLouds and Aerosol Radiative Impacts and Forcing: Year-2016 (CLARIFY-2016). Haywood, J.M., Osborne, S.R. Francis, P.N., Keil, A., Formenti, P., Andreae, M.O., and Kaye, P.H., The mean physical and optical properties of regional haze dominated by biomass burning aerosol measured from the C-130 aircraft during SAFARI 2000, J. Geophys. Res., 108(D13), 8473, doi:10.1029/2002JD002226, 2003. Johnson, B.T., K.P. Shine, and P.M. Forster, The semi-direct aerosol effect: Impact of absorbing aerosols on marine stratocumulus, QJRMS, DOI: 10.1256/qj.03.61, 2006. Myhre, G. et al. Radiative forcing of the direct aerosol effect from AeroCom Phase II simulations, Atmos. Chem. Phys., 13, 1853-1877, doi:10.5194/acp-13-1853-2013, 2013
NASA Technical Reports Server (NTRS)
Zhang, Feng; Wang, Jun; Ichoku, Charles; Hyer, Edward J.; Yang, Zhifeng; Ge, Cui; Su, Shenjian; Zhang, Xiaoyang; Kondragunta, Shobha; Kaiser, Johannes W.;
2014-01-01
An ensemble approach is used to examine the sensitivity of smoke loading and smoke direct radiative effect in the atmosphere to uncertainties in smoke emission estimates. Seven different fire emission inventories are applied independently to WRF-Chem model (v3.5) with the same model configuration (excluding dust and other emission sources) over the northern sub-Saharan African (NSSA) biomass-burning region. Results for November and February 2010 are analyzed, respectively representing the start and end of the biomass burning season in the study region. For February 2010, estimates of total smoke emission vary by a factor of 12, but only differences by factors of 7 or less are found in the simulated regional (15degW-42degE, 13degS-17degN) and monthly averages of column PM(sub 2.5) loading, surface PM(sub 2.5) concentration, aerosol optical depth (AOD), smoke radiative forcing at the top-of-atmosphere and at the surface, and air temperature at 2 m and at 700 hPa. The smaller differences in these simulated variables may reflect the atmospheric diffusion and deposition effects to dampen the large difference in smoke emissions that are highly concentrated in areas much smaller than the regional domain of the study. Indeed, at the local scale, large differences (up to a factor of 33) persist in simulated smoke-related variables and radiative effects including semi-direct effect. Similar results are also found for November 2010, despite differences in meteorology and fire activity. Hence, biomass burning emission uncertainties have a large influence on the reliability of model simulations of atmospheric aerosol loading, transport, and radiative impacts, and this influence is largest at local and hourly-to-daily scales. Accurate quantification of smoke effects on regional climate and air quality requires further reduction of emission uncertainties, particularly for regions of high fire concentrations such as NSSA.
NASA Astrophysics Data System (ADS)
Xie, Tianwu; Zaidi, Habib
2014-03-01
PET uses specific molecules labelled with positron-emitting radionuclides to provide valuable biochemical and physiological information. However, the administration of radiotracers to patients exposes them to low-dose ionizing radiation, which is a concern in the paediatric population since children are at a higher cancer risk from radiation exposure than adults. Therefore, radiation dosimety calculations for commonly used positron-emitting radiotracers in the paediatric population are highly desired. We evaluate the absorbed dose and effective dose for 19 positron-emitting labelled radiotracers in anthropomorphic paediatric models including the newborn, 1-, 5-, 10- and 15-year-old male and female. This is achieved using pre-calculated S-values of positron-emitting radionuclides of UF-NCI paediatric phantoms and published biokinetic data for various radiotracers. The influence of the type of anthropomorphic model, tissue weight factors and direct human- versus mouse-derived biokinetic data on the effective dose for paediatric phantoms was also evaluated. In the case of 18F-FDG, dosimetry calculations of reference paediatric patients from various dose regimens were also calculated. Among the considered radiotracers, 18F-FBPA and 15O-water resulted in the highest and lowest effective dose in the paediatric phantoms, respectively. The ICRP 103 updated tissue-weighting factors decrease the effective dose in most cases. Substantial differences of radiation dose were observed between direct human- versus mouse-derived biokinetic data. Moreover, the effect of using voxel- versus MIRD-type models on the calculation of the effective dose was also studied. The generated database of absorbed organ dose and effective dose for various positron-emitting labelled radiotracers using new generation computational models and the new ICRP tissue-weighting factors can be used for the assessment of radiation risks to paediatric patients in clinical practice. This work also contributes to a better understanding of the factors influencing patient-specific radiation dose calculation.
Advanced CMOS Radiation Effects Testing and Analysis
NASA Technical Reports Server (NTRS)
Pellish, J. A.; Marshall, P. W.; Rodbell, K. P.; Gordon, M. S.; LaBel, K. A.; Schwank, J. R.; Dodds, N. A.; Castaneda, C. M.; Berg, M. D.; Kim, H. S.;
2014-01-01
Presentation at the annual NASA Electronic Parts and Packaging (NEPP) Program Electronic Technology Workshop (ETW). The material includes an update of progress in this NEPP task area over the past year, which includes testing, evaluation, and analysis of radiation effects data on the IBM 32 nm silicon-on-insulator (SOI) complementary metal oxide semiconductor (CMOS) process. The testing was conducted using test vehicles supplied by directly by IBM.
ARM-Led Improvements Aerosols in Climate and Climate Models
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ghan, Steven J.; Penner, Joyce E.
2016-07-25
The DOE ARM program has played a foundational role in efforts to quantify aerosol effects on climate, beginning with the early back-of-the-envelope estimates of direct radiative forcing by anthropogenic sulfate and biomass burning aerosol (Penner et al., 1994). In this chapter we review the role that ARM has played in subsequent detailed estimates based on physically-based representations of aerosols in climate models. The focus is on quantifying the direct and indirect effects of anthropogenic aerosol on the planetary energy balance. Only recently have other DOE programs applied the aerosol modeling capability to simulate the climate response to the radiative forcing.
The radiation dosimeter on-board the FY-4 Satellite
NASA Astrophysics Data System (ADS)
Zhang, B.; Sun, Y.; Zhang, S.; Zhang, X.; Sun, Y.; Jing, T.
2017-12-01
The total radiation dose effect can lead to a decrease in the performance of satellite devices or materials. Accurately obtaining the total radiation dose during satellite operation could help to analyze the abnormality of payloads in orbit and optimize the design of radiation shielding. The radiation dosimeter is one of the space environmental monitoring devices on the "FY-4" satellite, which is a new generation of geostationary meteorological satellite. The dosimeter consists of 8 detectors, which are installed in different locations of the satellite, to obtain the total radiation dose with different shielding thickness and different orientations. To measure a total radiation dose up to 2000krad(Si), 100nm ion implantation RADFET was used. To improve the sensitivity of the dosimeter, the bias voltage of RADFET is set to 15V, and a 10V, 15-bit A/D is adopted to digitalize the RADFET's threshold voltage, which is increased as the total radiation dose grows. In addition, the temperature effect of RADFET is corrected from the measured temperature on orbit. The preliminary monitoring results show that the radiation dose is less than 35rad (Si) per day at 0.87 mm shielding thickness of equivalent aluminum in the geostationary orbit, and the dose in Y direction of the satellite is less than those in the X and Z directions. The radiation dose at the thickness of 3.87 mm equivalent aluminum is less than 1rad(Si)/day. It is found that the daily total dose measured by the dosimeter has a strong correlation with the flux of high energy electrons.
NASA Technical Reports Server (NTRS)
Popov, Dmitri; Maliev, Vecheslav; Jones, Jeffrey; Casey, Rachael C.
2007-01-01
Protecting crew from ionizing radiation is a key life sciences problem for long-duration space missions. The three major sources/types of radiation are found in space: galactic cosmic rays, trapped Van Allen belt radiation, and solar particle events. All present varying degrees of hazard to crews; however, exposure to high doses of any of these types of radiation ultimately induce both acute and long-term biological effects. High doses of space radiation can lead to the development of toxicity associated with the acute radiation syndrome (ARS) which could have significant mission impact, and even render the crew incapable of performing flight duties. The creation of efficient radiation protection technologies is considered an important target in space radiobiology, immunology, biochemistry and pharmacology. Two major mechanisms of cellular, organelle, and molecular destruction as a result of radiation exposure have been identified: 1) damage induced directly by incident radiation on the macromolecules they encounter and 2) radiolysis of water and generation of secondary free radicals and reactive oxygen species (ROS), which induce chemical bond breakage, molecular substitutions, and damage to biological molecules and membranes. Free-radical scavengers and antioxidants, which neutralize the damaging activities of ROS, are effective in reducing the impact of small to moderate doses of radiation. In the case of high doses of radiation, antioxidants alone may be inadequate as a radioprotective therapy. However, it remains a valuable component of a more holistic strategy of prophylaxis and therapy. High doses of radiation directly damage biological molecules and modify chemical bond, resulting in the main pathological processes that drive the development of acute radiation syndromes (ARS). Which of two types of radiation-induced cellular lethality that ultimately develops, apoptosis or necrosis, depends on the spectrum of incident radiation, dose, dose rate, and functional conditions of impacted cells/organisms. The administration of an experimental anti-radiation vaccine may provide an immunologically based, adjunct method of prevention or prophylaxis against clinical ARS. The administration of experimental anti-radiation serum (ARS) and the use of the blood dialysis methods, such as immune plasma-sorption, may assist in the clearance of radiation-specific toxins and may enhance established strategies for the mitigation of the biological effects leading to ARS, and should be evaluated for use on exploration-class space missions.
Grant, Eric J; Cologne, John B; Sharp, Gerald B; Eguchi, Hidetaka; Stevens, Richard G; Izumi, Shizue; Kim, Young-Min; Berrington de González, Amy; Ohishi, Waka; Nakachi, Kei
2018-02-01
Ionizing radiation and high levels of circulating estradiol are known breast cancer carcinogens. We investigated the risk of first primary postmenopausal breast cancer in relation to the combined effects of whole-body ionizing radiation exposure and prediagnostic levels of postmenopausal sex hormones, particularly bioavailable estradiol (bE 2 ). A nested case-control study of 57 incident breast cancer cases matched with 110 controls among atomic bomb survivors. Joint effects of breast radiation dose and circulating levels of sex hormones were assessed using binary regression and path analysis. Radiation exposure, higher levels of bE 2 , testosterone and progesterone, and established reproductive risk factors were positively associated with postmenopausal breast cancer risk. A test for mediation of the effect of radiation via bE 2 level suggested a small (14%) but significant mediation (p = 0.004). The estimated interaction between radiation and bE 2 was large but not significant (interaction = 3.86; p = 0.32). There is accumulating evidence that ionizing radiation not only damages DNA but also alters other organ systems. While caution is needed, some portion of the radiation risk of postmenopausal breast cancer appeared to be mediated through bE 2 levels, which may be evidence for cancer risks due to both direct and indirect effects of radiation.
Space Radiation Induced Cytogenetic Damage in the Blood Lymphocytes of Astronauts
NASA Technical Reports Server (NTRS)
George, K.; Cucinotta, F. A.
2008-01-01
Cytogenetic analysis of astronauts blood lymphocytes provides a direct in vivo measurement of space radiation damage, which takes into account individual radiosensitivity and considers the influence of microgravity and other stress conditions. We present our latest analyses of chromosome damage in astronauts blood lymphocytes assessed by fluorescence in situ hybridization (FISH) chromosome painting and collected at various times beginning directly after return from space to several years after flight. Dose was derived from frequencies of chromosome exchanges using preflight calibration curves, and the Relative Biological Effect (RBE) was estimated by comparison with individually measured physically absorbed doses. Values for average RBE were compared to the average quality factor (Q), from direct measurements of the lineal energy spectra using a tissue-equivalent proportional counter (TEPC) and radiation transport codes. Results prove that cytogenetic biodosimetry analyses on blood collected within a week or two of return from space provides a reliable estimate of equivalent radiation dose and risk after protracted exposure to space radiation of a few months or more. However, data collected several months or years after flight suggests that the yield of chromosome translocations may decline with time after the mission, indicating that retrospective doses may be more difficult to estimate. In addition, limited data on multiple flights show a lack of correlation between time in space and translocation yields. Data from one crewmember, who has participated in two separate long-duration space missions and has been followed up for over 10 years, provide limited information on the effect of repeat flights and show a possible adaptive response to space radiation exposure.
Possible directions of refining criteria of radiation safety of spaceflights
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kovalev, Y.Y.; Petrov, V.M.; Sakovich, V.A.
The possibility of characterizing space flight radiation safety is considered using a value which is integrated over the flight time, takes into account the radiation processes in an irradiated body and averages the probability of adverse radiobiological effects with respect to the distribution of solar proton flares of varying intensity. The proposed characteristic is compared with the current standards with reference to a hypothetic interplanetary flight.
Effects of finite ground plane on the radiation characteristics of a circular patch antenna
NASA Astrophysics Data System (ADS)
Bhattacharyya, Arun K.
1990-02-01
An analytical technique to determine the effects of finite ground plane on the radiation characteristics of a microstrip antenna is presented. The induced currents on the ground plane and on the upper surface of the patch are determined from the discontinuity of the near field produced by the equivalent magnetic current source on the physical aperture of the patch. The radiated fields contributed by the induced current on the ground plane and the equivalent sources on the physical aperture yield the radiation pattern of the antenna. Radiation patterns of the circular patch with finite ground plane size are computed and compared with the experimental data, and the agreement is found to be good. The radiation pattern, directive gain, and input impedance are found to vary widely with the ground plane size.
The influence of continuum radiation fields on hydrogen radio recombination lines
NASA Astrophysics Data System (ADS)
Prozesky, Andri; Smits, Derck P.
2018-05-01
Calculations of hydrogen departure coefficients using a model with the angular momentum quantum levels resolved that includes the effects of external radiation fields are presented. The stimulating processes are important at radio frequencies and can influence level populations. New numerical techniques with a solid mathematical basis have been incorporated into the model to ensure convergence of the solution. Our results differ from previous results by up to 20 per cent. A direct solver with a similar accuracy but more efficient than the iterative method is used to evaluate the influence of continuum radiation on the hydrogen population structure. The effects on departure coefficients of continuum radiation from dust, the cosmic microwave background, the stellar ionising radiation, and free-free radiation are quantified. Tables of emission and absorption coefficients for interpreting observed radio recombination lines are provided.
NASA Astrophysics Data System (ADS)
Rhee, Hyop S.; Begg, Lester L.; Wetch, Joseph R.; Jang, Jong H.; Juhasz, Albert J.
An innovative pumped loop concept for 600 K space power system radiators utilizing direct contact heat transfer, which facilitates repeated startup/shutdown of the power system without complex and time-consuming coolant thawing during power startup, is under development. The heat transfer process with melting/freezing of Li in an NaK flow was studied through two-dimensional time-dependent numerical simulations to characterize and predict the Li/NaK radiator performance during startup (thawing) and shutdown (cold-trapping). Effects of system parameters and the criteria for the plugging domain are presented together with temperature distribution patterns in solid Li and subsequent melting surface profile variations in time.
Repair of oxidative DNA damage by amino acids.
Milligan, J R; Aguilera, J A; Ly, A; Tran, N Q; Hoang, O; Ward, J F
2003-11-01
Guanyl radicals, the product of the removal of a single electron from guanine, are produced in DNA by the direct effect of ionizing radiation. We have produced guanyl radicals in DNA by using the single electron oxidizing agent (SCN)2-, itself derived from the indirect effect of ionizing radiation via thiocyanate scavenging of OH. We have examined the reactivity of guanyl radicals in plasmid DNA with the six most easily oxidized amino acids cysteine, cystine, histidine, methionine, tryptophan and tyrosine and also simple ester and amide derivatives of them. Cystine and histidine derivatives are unreactive. Cysteine, methionine, tyrosine and particularly tryptophan derivatives react to repair guanyl radicals in plasmid DNA with rate constants in the region of approximately 10(5), 10(5), 10(6) and 10(7) dm3 mol(-1) s(-1), respectively. The implication is that amino acid residues in DNA binding proteins such as histones might be able to repair by an electron transfer reaction the DNA damage produced by the direct effect of ionizing radiation or by other oxidative insults.
CALIPSO-Inferred Aerosol Direct Radiative Effects: Bias Estimates Using Ground-Based Raman Lidars
NASA Technical Reports Server (NTRS)
Thorsen, Tyler; Fu, Qiang
2016-01-01
Observational constraints on the change in the radiative energy budget caused by the presence of aerosols, i.e. the aerosol direct radiative effect (DRE), have recently been made using observations from the Cloud- Aerosol Lidar and Infrared Pathfinder Satellite (CALIPSO). CALIPSO observations have the potential to provide improved global estimates of aerosol DRE compared to passive sensor-derived estimates due to CALIPSO's ability to perform vertically-resolved aerosol retrievals over all surface types and over cloud. In this study we estimate the uncertainties in CALIPSO-inferred aerosol DRE using multiple years of observations from the Atmospheric Radiation Measurement (ARM) program's Raman lidars (RL) at midlatitude and tropical sites. Examined are assumptions about the ratio of extinction-to-backscatter (i.e. the lidar ratio) made by the CALIPSO retrievals, which are needed to retrieve the aerosol extinction profile. The lidar ratio is shown to introduce minimal error in the mean aerosol DRE at the top-of-atmosphere and surface. It is also shown that CALIPSO is unable to detect all radiatively-significant aerosol, resulting in an underestimate in the magnitude of the aerosol DRE by 30-50%. Therefore, global estimates of the aerosol DRE inferred from CALIPSO observations are likely too weak.
Estimating the direct radiative forcing due to haze from the 1997 forest fires in Indonesia
NASA Astrophysics Data System (ADS)
Davison, P. S.; Roberts, D. L.; Arnold, R. T.; Colvile, R. N.
2004-05-01
The El Niño event of 1997-1998 caused a severe reduction of rainfall in Indonesia that promoted the spread of forest fires, leading to a pervasive haze in the region. Here we use fire coverage data from the 1997 World Fire Atlas with a review of other available data and literature to estimate the distribution of particulate emissions from August to November 1997 and the particle size and radiative properties. Our preferred estimate of the total particulate emissions is approximately 41 Tg. The emissions have been used to drive an atmospheric model to simulate the distribution of the haze and its direct radiative effect, with and without allowing for the effects of the smoke on the atmospheric evolution. Model diagnostics of the aerosol and its radiative impact are compared with measurements and output from other models. Large decreases in the incident solar flux at the surface are obtained in the region. The simulated global mean shortwave radiative forcing at the top of the atmosphere, averaged over the 4 months, is -0.32 Wm-2. The accuracy of this calculation is discussed, and the importance of the Indonesian fires in particular and of biomass burning in general is assessed.
NASA Technical Reports Server (NTRS)
Morgan, William F.
2003-01-01
A number of nontargeted and delayed effects associated with radiation exposure have now been described. These include radiation-induced genomic instability, death-inducing and bystander effects, clastogenic factors and transgenerational effects. It is unlikely that these nontargeted effects are directly induced by cellular irradiation. Instead, it is proposed that some as yet to be identified secreted factor can be produced by irradiated cells that can stimulate effects in nonirradiated cells (death-inducing and bystander effects, clastogenic factors) and perpetuate genomic instability in the clonally expanded progeny of an irradiated cell. The proposed factor must be soluble and capable of being transported between cells by cell-to-cell gap junction communication channels. Furthermore, it must have the potential to stimulate cellular cytokines and/or reactive oxygen species. While it is difficult to imagine a role for such a secreted factor in contributing to transgenerational effects, the other nontargeted effects of radiation may all share a common mechanism.
The design of radiation-hardened ICs for space - A compendium of approaches
NASA Technical Reports Server (NTRS)
Kerns, Sherra E.; Shafer, B. D; Rockett, L. R., Jr.; Pridmore, J. S.; Berndt, D. F.
1988-01-01
Several technologies, including bulk and epi CMOS, CMOS/SOI-SOS (silicon-on-insulator-silicon-on-sapphire), CML (current-mode logic), ECL (emitter-coupled logic), analog bipolar (JI, single-poly DI, and SOI) and GaAs E/D (enhancement/depletion) heterojunction MESFET, are discussed. The discussion includes the direct effects of space radiation on microelectronic materials and devices, how these effects are evidenced in circuit and device design parameter variations, the particular effects of most significance to each functional class of circuit, specific techniques for hardening high-speed circuits, design examples for integrated systems, including operational amplifiers and A/D (analog/digital) converters, and the computer simulation of radiation effects on microelectronic ISs.
NASA Astrophysics Data System (ADS)
Sutikno, Madnasri; Susilo; Arya Wijayanti, Riza
2016-08-01
A study about X-ray radiation impact on the white mice through radiation dose mapping in Medical Physic Laboratory is already done. The purpose of this research is to determine the minimum distance of radiologist to X-ray instrument through treatment on the white mice. The radiation exposure doses are measured on the some points in the distance from radiation source between 30 cm up to 80 with interval of 30 cm. The impact of radiation exposure on the white mice and the effects of radiation measurement in different directions are investigated. It is founded that minimum distance of radiation worker to radiation source is 180 cm and X-ray has decreased leukocyte number and haemoglobin and has increased thrombocyte number in the blood of white mice.
Radiation Measured for Chinese Satellite SJ-10 Space Mission
NASA Astrophysics Data System (ADS)
Zhou, Dazhuang; Sun, Yeqing; Zhang, Binquan; Zhang, Shenyi; Sun, Yueqiang; Liang, Jinbao; Zhu, Guangwu; Jing, Tao; Yuan, Bin; Zhang, Huanxin; Zhang, Meng; Wang, Wei; Zhao, Lei
2018-02-01
Space biological effects are mainly a result of space radiation particles with high linear energy transfer (LET); therefore, accurate measurement of high LET space radiation is vital. The radiation in low Earth orbits is composed mainly of high-energy galactic cosmic rays (GCRs), solar energetic particles, particles of radiation belts, the South Atlantic Anomaly, and the albedo neutrons and protons scattered from the Earth's atmosphere. CR-39 plastic nuclear track detectors sensitive to high LET are the best passive detectors to measure space radiation. The LET method that employs CR-39 can measure all the radiation LET spectra and quantities. CR-39 detectors can also record the incident directions and coordinates of GCR heavy ions that pass through both CR-39 and biosamples, and the impact parameter, the distance between the particle's incident point and the seed's spore, can then be determined. The radiation characteristics and impact parameter of GCR heavy ions are especially beneficial for in-depth research regarding space radiation biological effects. The payload returnable satellite SJ-10 provided an excellent opportunity to investigate space radiation biological effects with CR-39 detectors. The space bio-effects experiment was successfully conducted on board the SJ-10 satellite. This paper introduces space radiation in low Earth orbits and the LET method in radiation-related research and presents the results of nuclear tracks and biosamples hitting distributions of GCR heavy ions, the radiation LET spectra, and the quantities measured for the SJ-10 space mission. The SJ-10 bio-experiment indicated that radiation may produce significant bio-effects.
Ozone formation in pulsed SDBD in a wide pressure range
NASA Astrophysics Data System (ADS)
Starikovskiy, Andrey; Nudnova, Maryia; mipt Team
2011-10-01
Ozone concentration in surface anode-directed DBD for wide pressure range (150 - 1300 torr) was experimentally measured. Voltage and pressure effect were investigated. Reduced electric field was measured for anode-directed and cathode-directed SDBD. E/n values in cathode-directed SDBD is higher than in cathode-directed on 50 percent at atmospheric pressure. E/n value increase leads to decrease the rate of oxygen dissociation and Ozone formation at lower pressures. Radiating region thickness of sliding discharge was measured. Typical thickness of radiating zone is 0.4-1.0 mm within pressure range 220-740 torr. It was shown that high-voltage pulsed nanosecond discharge due to high E/n value produces less Ozone with compare to other discharges. Kinetic model was proposed to describe Ozone formation in the pulsed nanosecond SDBD.
bhlight: General Relativistic Radiation Magnetohydrodynamics with Monte Carlo Transport
Ryan, Benjamin R; Dolence, Joshua C.; Gammie, Charles F.
2015-06-25
We present bhlight, a numerical scheme for solving the equations of general relativistic radiation magnetohydrodynamics using a direct Monte Carlo solution of the frequency-dependent radiative transport equation. bhlight is designed to evolve black hole accretion flows at intermediate accretion rate, in the regime between the classical radiatively efficient disk and the radiatively inefficient accretion flow (RIAF), in which global radiative effects play a sub-dominant but non-negligible role in disk dynamics. We describe the governing equations, numerical method, idiosyncrasies of our implementation, and a suite of test and convergence results. We also describe example applications to radiative Bondi accretion and tomore » a slowly accreting Kerr black hole in axisymmetry.« less
NASA Astrophysics Data System (ADS)
Li, Xiaoqiong; Ting, Mingfang
2017-10-01
Future hydroclimate projections from state-of-the-art climate models show large uncertainty and model spread, particularly in the tropics and over the monsoon regions. The precipitation and circulation responses to rising greenhouse gases involve a fast component associated with direct radiative forcing and a slow component associated with sea surface temperature (SST) warming; the relative importance of the two may contribute to model discrepancies. In this study, regional hydroclimate responses to greenhouse warming are assessed using output from coupled general circulation models in the Coupled Model Intercomparison Project-Phase 5 (CMIP5) and idealized atmospheric general circulation model experiments from the Atmosphere Model Intercomparison Project. The thermodynamic and dynamic mechanisms causing the rainfall changes are examined using moisture budget analysis. Results show that direct radiative forcing and SST change exert significantly different responses both over land and ocean. For most part of the Asian monsoon region, the summertime rainfall changes are dominated by the direct CO2 radiative effect through enhanced monsoon circulation. The response to SST warming shows a larger model spread compared to direct radiative forcing, possibly due to the cancellation between the thermodynamical and dynamical components. While the thermodynamical response of the Asian monsoon is robust across the models, there is a lack of consensus for the dynamical response among the models and weak multi-model mean responses in the CMIP5 ensemble, which may be related to the multiple physical processes evolving on different time scales.
[Dose rate-dependent cellular and molecular effects of ionizing radiation].
Przybyszewski, Waldemar M; Wideł, Maria; Szurko, Agnieszka; Maniakowski, Zbigniew
2008-09-11
The aim of radiation therapy is to kill tumor cells while minimizing damage to normal cells. The ultimate effect of radiation can be apoptotic or necrotic cell death as well as cytogenetic damage resulting in genetic instability and/or cell death. The destructive effects of radiation arise from direct and indirect ionization events leading to peroxidation of macromolecules, especially those present in lipid-rich membrane structures as well as chromatin lipids. Lipid peroxidative end-products may damage DNA and proteins. A characteristic feature of radiation-induced peroxidation is an inverse dose-rate effect (IDRE), defined as an increase in the degree of oxidation(at constant absorbed dose) accompanying a lower dose rate. On the other hand, a low dose rate can lead to the accumulation of cells in G2, the radiosensitive phase of the cell cycle since cell cycle control points are not sensitive to low dose rates. Radiation dose rate may potentially be the main factor improving radiotherapy efficacy as well as affecting the intensity of normal tissue and whole-body side effects. A better understanding of dose rate-dependent biological effects may lead to improved therapeutic intervention and limit normal tissue reaction. The study reviews basic biological effects that depend on the dose rate of ionizing radiation.
NASA Technical Reports Server (NTRS)
Remer, L. A.; Kaufman, Y. J.
2006-01-01
A four year record of MODIS spaceborne data provides a new measurement tool to assess the aerosol direct radiative effect at the top of the atmosphere. MODIS derives the aerosol optical thickness and microphysical properties from the scattered sunlight at 0.55-2.1 microns. The monthly MODIS data used here are accumulated measurements across a wide range of view and scattering angles and represent the aerosol s spectrally resolved angular properties. We use these data consistently to compute with estimated accuracy of +/-0.6W/sq m the reflected sunlight by the aerosol over global oceans in cloud free conditions. The MODIS high spatial resolution (0.5 km) allows observation of the aerosol impact between clouds that can be missed by other sensors with larger footprints. We found that over the clear-sky global ocean the aerosol reflected 5.3+/-0.6W/sq m with an average radiative efficiency of 49+/-2W/sq m per unit optical thickness. The seasonal and regional distribution of the aerosol radiative effects are discussed. The analysis adds a new measurement perspective to a climate change problem dominated so far by models.
Direct radiative effect by multicomponent aerosol over China
DOE Office of Scientific and Technical Information (OSTI.GOV)
Huang, Xin; Song, Yu; Zhao, Chun
The direct radiative effect (DRE) of multiple aerosol species (sulfate, nitrate, ammonium, black carbon (BC), organic carbon (OC), and mineral aerosol) and their spatiotemporal variations over China were investigated using a fully coupled meteorology–chemistry model (WRF-Chem) for the entire year of 2006. We made modifications to improve model performance, including updating land surface parameters, improving the calculation of transition metal-catalyzed oxidation of SO 2, and adding in heterogeneous reactions between mineral aerosol and acid gases. The modified model well reproduced the magnitude, seasonal pattern, and spatial distribution of the measured meteorological conditions, concentrations of PM 10 and its components, andmore » aerosol optical depth (AOD). A diagnostic iteration method was used to estimate the overall DRE of aerosols and contributions from different components. At the land surface, all kinds of aerosol species reduced the incident net radiation flux with a total DRE of 10.2 W m -2 over China. Aerosols significantly warm the atmosphere with the national mean DRE of +10.8 W m -2. BC was the leading radiative-heating component (+8.7 W m -2), followed by mineral aerosol (+1.1 W m -2). At the top of the atmosphere (TOA), BC introduced the largest radiative perturbation (+4.5 W m -2), followed by sulfate (-1.4 W m -2). The overall perturbation of aerosols on radiation transfer is quite small over China, demonstrating the counterbalancing effect between scattering and adsorbing aerosols. Aerosol DRE at the TOA had distinct seasonality, generally with a summer maximum and winter minimum, mainly determined by mass loadings, hygroscopic growth, and incident radiation flux.« less
[Research on cells ablation characters by laser plasma].
Han, Jing-hua; Zhang, Xin-gang; Cai, Xiao-tang; Duan, Tao; Feng, Guo-ying; Yang, Li-ming; Zhang, Ya-jun; Wang, Shao-peng; Li, Shi-wen
2012-08-01
The study on the mechanism of laser ablated cells is of importance to laser surgery and killing harmful cells. Three radiation modes were researched on the ablation characteristics of onion epidermal cells under: laser direct irradiation, focused irradiation and the laser plasma radiation. Based on the thermodynamic properties of the laser irradiation, the cell temperature rise and phase change have been analyzed. The experiments show that the cells damage under direct irradiation is not obvious at all, but the focused irradiation can cause cells to split and moisture removal. The removal shape is circular with larger area and rough fracture edges. The theoretical analysis found out that the laser plasma effects play a key role in the laser ablation. The thermal effects, radiation ionization and shock waves can increase the deposition of laser pulses energy and impact peeling of the cells, which will greatly increase the scope and efficiency of cell killing and is suitable for the cell destruction.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lipshits, R.U.; Kratinova, M.A.
1977-01-01
Rats were given intraperitoneal injections of antigen and exposed to 200 R of gamma radiation. Acetylcholine content and cholinesterase activity of blood were analyzed every 5 days for 30 days. The interval between sensitization and irradiation determined the direction of changes in allergic reactions. The radiation appreciably attenuated active sensitization of rats. The degree of sensitization was related to changes in cholinergic processes. The data confirmed the assumption that cholinergic systems are involved in the mechanisms of change in allergic reactivity under the influence of radiation. (HLW)
NASA Technical Reports Server (NTRS)
Loeb, N. G.; Kato, S.
2002-01-01
Nine months of CERES/TRMM broadband fluxes combined with VIRS high-resolution imager measurements are used to estimate the daily average direct radiative effect of aerosols for clear-sky conditions over the tropical oceans. On average, aerosols have a cooling effect over the tropics of 4.6 +/- 1 W/sq m. The magnitude is approx.2 W/sq m smaller over the southern tropical oceans than it is over northern tropical oceans. The direct effect derived from CERES is highly correlated with coincident aerosol optical depth retrievals inferred from 0.63 microns VIRS radiances (correlation coefficient of 0.96). The slope of the regression line is approx. -32 W/sq m/t over the equatorial Pacific Ocean, but changes both regionally and seasonally, depending on the aerosol characteristics. Near sources of biomass burning and desert dust, the aerosol direct effect reaches -25 W sq m to -30 W/sq m. The direct effect from CERES also shows a dependence on wind speed. The reason for this dependence is unclear-it may be due to increased aerosol (e.g. sea-salt or aerosol transport) or increased surface reflection (e.g. due to whitecaps). The uncertainty in the tropical average direct effect from CERES is approx. 1 W/sq m (approx. 20%) due mainly to cloud contamination, the radiance-to-flux conversion, and instrument calibration. By comparison, uncertainties in the direct effect from the ERBE and CERES "ERBE-Like" products are a factor of 3 to 5 larger.
Note: Soft X-ray transmission polarizer based on ferromagnetic thin films
NASA Astrophysics Data System (ADS)
Müller, L.; Hartmann, G.; Schleitzer, S.; Berntsen, M. H.; Walther, M.; Rysov, R.; Roseker, W.; Scholz, F.; Seltmann, J.; Glaser, L.; Viefhaus, J.; Mertens, K.; Bagschik, K.; Frömter, R.; De Fanis, A.; Shevchuk, I.; Medjanik, K.; Öhrwall, G.; Oepen, H. P.; Martins, M.; Meyer, M.; Grübel, G.
2018-03-01
A transmission polarizer for producing elliptically polarized soft X-ray radiation from linearly polarized light is presented. The setup is intended for use at synchrotron and free-electron laser beamlines that do not directly offer circularly polarized light for, e.g., X-ray magnetic circular dichroism (XMCD) measurements or holographic imaging. Here, we investigate the degree of ellipticity upon transmission of linearly polarized radiation through a cobalt thin film. The experiment was performed at a photon energy resonant to the Co L3-edge, i.e., 778 eV, and the polarization of the transmitted radiation was determined using a polarization analyzer that measures the directional dependence of photo electrons emitted from a gas target. Elliptically polarized radiation can be created at any absorption edge showing the XMCD effect by using the respective magnetic element.
On the performance of infrared sensors in earth observations
NASA Technical Reports Server (NTRS)
Johnson, L. F.
1972-01-01
The performance of infrared sensing systems is dependent upon the radiative properties of targets in addition to constraints imposed by system components. The unclassified state-of-the-art of infrared system performance figures is reviewed to indicate the relevance to system performance of target radiative properties. A theory of rough surface scattering is developed which allows the formulation of the reflective characteristics of extended targets. The thermal radiation emission from extended targets is formulated on the basis of internal radiation characteristics of natural materials and the transmissive scattering effects at the surface. Finally, the total radiative characteristics may be expressed as functions of material properties and incident and received directions, although the expressions are extremely complex functions and do not account for the effects of shadowing or multiple scattering. It is believed that the theory may be extended to include these effects and to incorporate the local radii of curvature of the surface.
The Elephant in the Room: Biomedical Challenges for Long Duration Lunar Habitation
NASA Technical Reports Server (NTRS)
Logan, James S.
2009-01-01
This slide presentation reviews 4 biomedical challenges that are involved in long duration lunar habitation: dust, radiation, hypogravity and synergistic effects. The first two of these challenges are reviewed with more in-depth information. The dangers of dust relate to the particle deposition in the lungs. The dangers of radiation are related to the permissible exposure limit (PEL) and the Risk of Exposure Induced Death (REID), a statistical approach pegged to a single radiation effect: Death from cancer directly attributable to the exposure. There has been a realization that radiation is more harmful than predicted. This is demonstrated by showing the change in the recommended career dose limits, have changed between 1989 and 2000.
Unexpected impact of radiation friction: enhancing production of longitudinal plasma waves.
Gelfer, Evgeny; Elkina, Nina; Fedotov, Alexander
2018-04-24
We study the penetration of ultra-intense (intensity I [Formula: see text] 10 23-24 W/cm 2 ) circularly polarized laser pulses into a thick subcritical plasma layer with accounting for radiation friction. We show that radiation pressure is enhanced due to radiation friction in the direction transverse to the laser pulse propagation, and that for stronger and longer laser pulses this mechanism dominates over the ordinary ponderomotive pressure, thus resulting in a substantionaly stronger charge separation than anticipated previously. We give estimates of the effect and compare them with the results of one and two dimensional particle-in-cell simulations. This effect can be important for laser-based acceleration schemes.
Task Order Final Report for the Period 20 January 2003 to 19 January 2005 (Northrop Grumman)
2005-04-01
34Nonlinear optical characterization of retinal molecules," Laser and Noncoherent Light Ocular Effects: Epidemiology, Prevention, and Treatment III, Bruce E...BIOEFFECTS DIVISION OPTICAL RADIATION BRANCH 2624 LOUIS BAUER DRIVE BROOKS CITY-BASE TX 78235 April2005 Approved for public release, distribution...SPONSORIMONITOR’S ACRONYM(S) Air Force Research Laboratory AFRL/HE Human Effectiveness Directorate, Directed Energy Bioeffects Division Optical Radiation
NASA Technical Reports Server (NTRS)
Cranmer, Steven R.; Owocki, Stanley P.
1995-01-01
We calculate the radiative driving force for winds around rapidly rotating oblate B stars, and we estimate the impact these forces should have on the production of a wind compressed disk. The effects of limb darkening, gravity darkening, oblateness, and an arbitrary wind velocity field are included in the computation of vector 'oblate finite disk' (OFD) factors, which depend on both radius and colatitude in the wind. The impact of limb darkening alone, with or without rotation, can increase the mass loss by as much as 10% over values computed using the standard uniformly bright spherical finite disk factor. For rapidly rotating stars, limb darkening makes 'sub-stellar' gravity darkening the dominant effect in the radial and latitudinal OFD factors, and lessens the impact of gravity darkening at other visible latitudes (nearer to the oblate limb). Thus, the radial radiative driving is generally stronger over the poles and weaker over the equator, following the gravity darkening at these latitudes. The nonradial radiative driving is considerably smaller in magnitude than the radial component, but is directed both away from the equatorial plane and in a retrograde azimuthal direction, acting to decrease the effective stellar rotation velocity. These forces thus weaken the equatorward wind compression compared to wind models computed with nonrotating finite disk factors.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kim, Dong-Hoon; Trippe, Sascha, E-mail: ki13130@gmail.com, E-mail: trippe@astro.snu.ac.kr
Understanding the interaction of primordial gravitational waves (GWs) with the Cosmic Microwave Background (CMB) plasma is important for observational cosmology. In this article, we provide an analysis of an apparently as-yet-overlooked effect. We consider a single free electric charge and suppose that it can be agitated by primordial GWs propagating through the CMB plasma, resulting in periodic, regular motion along particular directions. Light reflected by the charge will be partially polarized, and this will imprint a characteristic pattern on the CMB. We study this effect by considering a simple model in which anisotropic incident electromagnetic (EM) radiation is rescattered bymore » a charge sitting in spacetime perturbed by GWs, and becomes polarized. As the charge is driven to move along particular directions, we calculate its dipole moment to determine the leading-order rescattered EM radiation. The Stokes parameters of the rescattered radiation exhibit a net linear polarization. We investigate how this polarization effect can be schematically represented out of the Stokes parameters. We work out the representations of gradient modes (E-modes) and curl modes (B-modes) to produce polarization maps. Although the polarization effect results from GWs, we find that its representations, the E- and B-modes, do not practically reflect the GW properties such as strain amplitude, frequency, and polarization states.« less
Strong radiative heating due to the mixing state of black carbon in atmospheric aerosols.
Jacobson, M Z
2001-02-08
Aerosols affect the Earth's temperature and climate by altering the radiative properties of the atmosphere. A large positive component of this radiative forcing from aerosols is due to black carbon--soot--that is released from the burning of fossil fuel and biomass, and, to a lesser extent, natural fires, but the exact forcing is affected by how black carbon is mixed with other aerosol constituents. From studies of aerosol radiative forcing, it is known that black carbon can exist in one of several possible mixing states; distinct from other aerosol particles (externally mixed) or incorporated within them (internally mixed), or a black-carbon core could be surrounded by a well mixed shell. But so far it has been assumed that aerosols exist predominantly as an external mixture. Here I simulate the evolution of the chemical composition of aerosols, finding that the mixing state and direct forcing of the black-carbon component approach those of an internal mixture, largely due to coagulation and growth of aerosol particles. This finding implies a higher positive forcing from black carbon than previously thought, suggesting that the warming effect from black carbon may nearly balance the net cooling effect of other anthropogenic aerosol constituents. The magnitude of the direct radiative forcing from black carbon itself exceeds that due to CH4, suggesting that black carbon may be the second most important component of global warming after CO2 in terms of direct forcing.
Climate effects of reducing black carbon emissions: Dependence on location of emission
NASA Astrophysics Data System (ADS)
Fuglestvedt, J.; Berntsen, T.; Myhre, G.; Rive, N. A.; Rypdal, K.; Gerland, S.; Pedersen, C.; Strøm, J.
2006-12-01
The role played by emissions of black carbon aerosols (BC) on the Earth's climate is diverse and the overall effect is still quite uncertain: Black carbon not only absorbs sunlight (direct effect), but it also has a semi- direct effect on clouds, and when deposited on snow and ice it changes the reflectivity (albedo) of the ground surface. These mechanisms generally have a warming effect on the climate. This poster presents a Norwegian project that focus on the net effect of current BC emissions and future possible reductions in emissions of BC aerosols, taking into account scientific, economic, and political perspectives on the inclusion of BC in climate policies. Thus, the scope of the project is interdisciplinary and includes observations in the Arctic, model simulations of dispersion of BC aerosols, its radiative forcing and climate effects. Some initial results from measurements of BC content in snow from the Norwegian Arctic and corresponding measurements for surface reflectance will be presented. The radiative forcing of BC emissions from different geographical regions differs due to differences in the removal processes (i.e. the lifetime) and the amount of solar radiation available for absorption (depends on latitude, clouds, and surface albedo). The atmospheric burdens and RF (of the direct effect) of regional BC emissions from fossil fuel sources have been calculated by the global chemical transport model Oslo-CTM2 and a radiative transfer model, and first results of time-integrated RF per unit of emission (equivalent to absolute GWPs) are presented. Future plans including i) analysis of cost effective emission reduction strategies, taking into account regional differences the forcing efficiencies, but also cost estimates for BC reductions in the different regions, and ii) an evaluation of the climate effects of the emission reductions through model simulations, including climatic, economic and political perspectives exploring obstacles and opportunities will also be presented.
Boyd, Marie; Ross, Susan C; Dorrens, Jennifer; Fullerton, Natasha E; Tan, Ker Wei; Zalutsky, Michael R; Mairs, Robert J
2006-06-01
Recent studies have shown that indirect effects of ionizing radiation may contribute significantly to the effectiveness of radiotherapy by sterilizing malignant cells that are not directly hit by the radiation. However, there have been few investigations of the importance of indirect effects in targeted radionuclide treatment. Our purpose was to compare the induction of bystander effects by external beam gamma-radiation with those resultant from exposure to 3 radiohaloanalogs of metaiodobenzylguanidine (MIBG): (131)I-MIBG (low-linear-energy-transfer [LET] beta-emitter), (123)I-MIBG (potentially high-LET Auger electron emitter), and meta-(211)At-astatobenzylguanidine ((211)At-MABG) (high-LET alpha-emitter). Two human tumor cell lines-UVW (glioma) and EJ138 (transitional cell carcinoma of bladder)-were transfected with the noradrenaline transporter (NAT) gene to enable active uptake of MIBG. Medium from cells that accumulated the radiopharmaceuticals or were treated with external beam radiation was transferred to cells that had not been exposed to radioactivity, and clonogenic survival was determined in donor and recipient cultures. Over the dose range 0-9 Gy of external beam radiation of donor cells, 2 Gy caused 30%-40% clonogenic cell kill in recipient cultures. This potency was maintained but not increased by higher dosage. In contrast, no corresponding saturation of bystander cell kill was observed after treatment with a range of activity concentrations of (131)I-MIBG, which resulted in up to 97% death of donor cells. Cellular uptake of (123)I-MIBG and (211)At-MABG induced increasing recipient cell kill up to levels that resulted in direct kill of 35%-70% of clonogens. Thereafter, the administration of higher activity concentrations of these high-LET emitters was inversely related to the kill of recipient cells. Over the range of activity concentrations examined, neither direct nor indirect kill was observed in cultures of cells not expressing the NAT and, thus, incapable of active uptake of MIBG. Potent toxins are generated specifically by cells that concentrate radiohalogenated MIBG. These may be LET dependent and distinct from those elicited by conventional radiotherapy.
Radiation characteristics of Leaky Surface Plasmon polaritons of graphene
NASA Astrophysics Data System (ADS)
Mohadesi, V.; Asgari, A.; Siahpoush, V.
2018-07-01
High efficient coupling of graphene surface plasmons to far field radiation is possible by some techniques and can be used in the radiating applications. Besides of the coupling efficiency, the angular distribution of the radiated power is an important parameter in the radiating devices performance. In this paper we investigate the gain of the far field radiation related to the coupling of graphene surface plasmons via a high permittivity medium located close to the graphene. Our results show that high directive radiation and high coupling efficiency can be obtained by this technique and gain and directivity of radiation can be modified by graphene characteristics such as chemical potential and also quality of the graphene. Raising the chemical potential of graphene leads to increase the gain of the radiation as the result of amplifying the directivity of the radiation. Furthermore, high values of relaxation time lead to high directive and strong coupling which raises the maximum value of gain in efficient coupling angle. Tunable characteristics of gain and directivity in this structure can be important designing reconfigurable THz radiating devices.
Experimental study of the effects of installation on singleand counter-rotation propeller noise
NASA Technical Reports Server (NTRS)
Block, P. J. W.
1986-01-01
Measurements which are required to define the directivity and the level of propeller noise were studied. The noise radiation pattern for various single-rotation (SR) propeller and counter-rotation (CR) propeller installations were mapped. The measurements covered + or - 60 deg from the propeller disk plane and + or - 60 deg in the cross-stream direction. Configurations examined included SR and CR propellers at angle of attack and an SR pusher installation. The increases in noise that arise from an unsteady loading operation such as an SR pusher or a CR exceeded 15 dB in the forward axial direction. Most of the additional noise radiates in the axial directions for unsteady loading operations of both the SR pusher and the CR tractor.
Uncertainties in global aerosols and climate effects due to biofuel emissions
NASA Astrophysics Data System (ADS)
Kodros, J. K.; Scott, C. E.; Farina, S. C.; Lee, Y. H.; L'Orange, C.; Volckens, J.; Pierce, J. R.
2015-04-01
Aerosol emissions from biofuel combustion impact both health and climate; however, while reducing emissions through improvements to combustion technologies will improve health, the net effect on climate is largely unconstrained. In this study, we examine sensitivities in global aerosol concentration, direct radiative climate effect, and cloud-albedo aerosol indirect climate effect to uncertainties in biofuel emission factors, optical mixing-state, and model nucleation and background SOA. We use the Goddard Earth Observing System global chemical-transport model (GEOS-Chem) with TwO Moment Aerosol Sectional (TOMAS) microphysics. The emission factors include: amount, composition, size and hygroscopicity, as well as optical mixing-state properties. We also evaluate emissions from domestic coal use, which is not biofuel but is also frequently emitted from homes. We estimate the direct radiative effect assuming different mixing states (internal, core-shell, and external) with and without absorptive organic aerosol (brown carbon). We find the global-mean direct radiative effect of biofuel emissions ranges from -0.02 to +0.06 W m-2 across all simulation/mixing state combinations with regional effects in source regions ranging from -0.2 to +1.2 W m-2. The global-mean cloud-albedo aerosol indirect effect ranges from +0.01 to -0.02 W m-2 with regional effects in source regions ranging from -1.0 to -0.05 W m-2. The direct radiative effect is strongly dependent on uncertainties in emissions mass, composition, emissions aerosol size distributions and assumed optical mixing state, while the indirect effect is dependent on the emissions mass, emissions aerosol size distribution and the choice of model nucleation and secondary organic aerosol schemes. The sign and magnitude of these effects have a strong regional dependence. We conclude that the climate effects of biofuel aerosols are largely unconstrained, and the overall sign of the aerosol effects is unclear due to uncertainties in model inputs. This uncertainty limits our ability to introduce mitigation strategies aimed at reducing biofuel black carbon emissions in order to counter warming effects from greenhouse-gases. To better understand the climate impact of particle emissions from biofuel combustion, we recommend field/laboratory measurements to narrow constraints on: (1) emissions mass, (2) emission size distribution, (3) mixing state, and (4) ratio of black carbon to organic aerosol.
Uncertainties in global aerosols and climate effects due to biofuel emissions
NASA Astrophysics Data System (ADS)
Kodros, J. K.; Scott, C. E.; Farina, S. C.; Lee, Y. H.; L'Orange, C.; Volckens, J.; Pierce, J. R.
2015-08-01
Aerosol emissions from biofuel combustion impact both health and climate; however, while reducing emissions through improvements to combustion technologies will improve health, the net effect on climate is largely unconstrained. In this study, we examine sensitivities in global aerosol concentration, direct radiative climate effect, and cloud-albedo aerosol indirect climate effect to uncertainties in biofuel emission factors, optical mixing state, and model nucleation and background secondary organic aerosol (SOA). We use the Goddard Earth Observing System global chemical-transport model (GEOS-Chem) with TwO Moment Aerosol Sectional (TOMAS) microphysics. The emission factors include amount, composition, size, and hygroscopicity, as well as optical mixing-state properties. We also evaluate emissions from domestic coal use, which is not biofuel but is also frequently emitted from homes. We estimate the direct radiative effect assuming different mixing states (homogeneous, core-shell, and external) with and without absorptive organic aerosol (brown carbon). We find the global-mean direct radiative effect of biofuel emissions ranges from -0.02 to +0.06 W m-2 across all simulation/mixing-state combinations with regional effects in source regions ranging from -0.2 to +0.8 W m-2. The global-mean cloud-albedo aerosol indirect effect (AIE) ranges from +0.01 to -0.02 W m-2 with regional effects in source regions ranging from -1.0 to -0.05 W m-2. The direct radiative effect is strongly dependent on uncertainties in emissions mass, composition, emissions aerosol size distributions, and assumed optical mixing state, while the indirect effect is dependent on the emissions mass, emissions aerosol size distribution, and the choice of model nucleation and secondary organic aerosol schemes. The sign and magnitude of these effects have a strong regional dependence. We conclude that the climate effects of biofuel aerosols are largely unconstrained, and the overall sign of the aerosol effects is unclear due to uncertainties in model inputs. This uncertainty limits our ability to introduce mitigation strategies aimed at reducing biofuel black carbon emissions in order to counter warming effects from greenhouse gases. To better understand the climate impact of particle emissions from biofuel combustion, we recommend field/laboratory measurements to narrow constraints on (1) emissions mass, (2) emission size distribution, (3) mixing state, and (4) ratio of black carbon to organic aerosol.
NASA Astrophysics Data System (ADS)
Strada, Susanna; Unger, Nadine
2016-04-01
A global Earth system model is applied to quantify the impacts of direct anthropogenic aerosol effective radiative forcing on gross primary productivity (GPP) and isoprene emission. The impacts of different pollution aerosol sources (anthropogenic, biomass burning, and non-biomass burning) are investigated by performing sensitivity experiments. The model framework includes all known light and meteorological responses of photosynthesis, but uses fixed canopy structures and phenology. On a global scale, our results show that global land carbon fluxes (GPP and isoprene emission) are not sensitive to pollution aerosols, even under a global decline in surface solar radiation (direct + diffuse) by ˜ 9 %. At a regional scale, GPP and isoprene emission show a robust but opposite sensitivity to pollution aerosols in regions where forested canopies dominate. In eastern North America and Eurasia, anthropogenic pollution aerosols (mainly from non-biomass burning sources) enhance GPP by +5-8 % on an annual average. In the northwestern Amazon Basin and central Africa, biomass burning aerosols increase GPP by +2-5 % on an annual average, with a peak in the northwestern Amazon Basin during the dry-fire season (+5-8 %). The prevailing mechanism varies across regions: light scattering dominates in eastern North America, while a reduction in direct radiation dominates in Europe and China. Aerosol-induced GPP productivity increases in the Amazon and central Africa include an additional positive feedback from reduced canopy temperatures in response to increases in canopy conductance. In Eurasia and northeastern China, anthropogenic pollution aerosols drive a decrease in isoprene emission of -2 to -12 % on an annual average. Future research needs to incorporate the indirect effects of aerosols and possible feedbacks from dynamic carbon allocation and phenology.
Radiation-Related Risk Analysis for Atmospheric Flight Civil Aviation Flight Personnel
NASA Technical Reports Server (NTRS)
DeAngelis, G.; Wilson, J. W.
2003-01-01
Human data on low dose rate radiation exposure and consequent effects are not readily available, and this fact generates groundtruth concerns for all risk assessment techniques for possible health effects induced by the space radiation environment, especially for long term missions like those foreseen now and in the near future. A large amount of such data may be obtained through civil aviation flight personnel cohorts, in the form of epidemiological studies on delayed health effects induced by the cosmic-ray generated atmospheric radiation environment, a high- LET low dose and low dose rate ionizing radiation with its typical neutron component, to which flight personnel are exposed all throughout their work activity. In the perspective of worldwide studies on radiation exposure of the civil aviation flight personnel, all the available results from previous studies on flight personnel radiation exposure have been examined in various ways (i.e. literature review, meta-analysis) to evaluate possible significant associations between atmospheric ionizing radiation environment and health risks, and to assess directions for future investigations. The physical characteristics of the atmospheric ionizing radiation environment make the results obtained for atmospheric flight personnel relevant for space exploration.
NASA Astrophysics Data System (ADS)
Curtis, S. B.; Luebeck, E. G.; Hazelton, W. D.; Moolgavkar, S. H.
When applied to the Colorado Plateau miner population, the two-stage clonal expansion (TSCE) model of radiation carcinogenesis predicts that radiation-induced promotion dominates radiation-induced initiation. Thus, according to the model, at least for alpha-particle radiation from inhaled radon daughters, lung cancer induction over long periods of protracted irradiation appears to be dominated by radiation-induced modification of the proliferation kinetics of already-initiated cells rather than by direct radiation-induced initiation (i.e., mutation) of normal cells. We explore the possible consequences of this result for radiation exposures to space travelers on long missions. Still unknown is the LET dependence of this effect. Speculations of the cause of this phenomenon include the suggestion that modification of cell kinetics is caused by a "bystander" effect, i.e., the traversal of normal cells by alpha particles, followed by the signaling of these cells to nearby initiated cells which then modify their proliferation kinetics.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jensh, R.P.; Brent, R.L.
1988-11-01
It is evident that significant permanent tissue hypoplasia can be produced following radiation exposure late in fetal development. Because two organs, brain and testes, are developmentally and functionally interrelated, it was of interest to determine whether fetal testicular hypoplasia was a primary or a secondary effect of fetal brain irradiation. Twenty-four pregnant Wistar strain rats were randomly assigned to one of four groups, and a laparotomy was performed on day 18 of gestation. The fetuses received sham irradiation, whole body irradiation, or only head/thorax or pelvic body irradiation at a dosage level of 1.5 Gy. Mothers were allowed to delivermore » and raise their offspring until postnatal day 30, when the offspring were weaned. At 60 days of age, 74 male offspring were allowed to mate with colony control females of similar age until successful insemination or until the males reached 90 days of age, when they were killed. Testes were weighed and processed for histologic examination. Direct radiation of testes, due to whole body or pelvic exposure, resulted in testicular growth retardation and significantly reduced spermatogenesis. Breeding activity of the males and the percent of positive inseminations were also slightly reduced. However, a significant percentage of male offspring receiving direct testicular radiation did produce offspring. Head/thorax-only irradiation did not adversely affect testicular growth or spermatogenesis. Therefore, the use of histologic analysis as the sole determinant of infertility may be misleading. This study indicates that testicular growth retardation and an increased infertility rate result from direct prenatal exposure of rat testes to X-radiation and are not necessarily mediated via X-irradiation effects on the central nervous system.« less
NASA Astrophysics Data System (ADS)
Stier, P.; Schutgens, N. A. J.; Bellouin, N.; Bian, H.; Boucher, O.; Chin, M.; Ghan, S.; Huneeus, N.; Kinne, S.; Lin, G.; Ma, X.; Myhre, G.; Penner, J. E.; Randles, C. A.; Samset, B.; Schulz, M.; Takemura, T.; Yu, F.; Yu, H.; Zhou, C.
2013-03-01
Simulated multi-model "diversity" in aerosol direct radiative forcing estimates is often perceived as a measure of aerosol uncertainty. However, current models used for aerosol radiative forcing calculations vary considerably in model components relevant for forcing calculations and the associated "host-model uncertainties" are generally convoluted with the actual aerosol uncertainty. In this AeroCom Prescribed intercomparison study we systematically isolate and quantify host model uncertainties on aerosol forcing experiments through prescription of identical aerosol radiative properties in twelve participating models. Even with prescribed aerosol radiative properties, simulated clear-sky and all-sky aerosol radiative forcings show significant diversity. For a purely scattering case with globally constant optical depth of 0.2, the global-mean all-sky top-of-atmosphere radiative forcing is -4.47 Wm-2 and the inter-model standard deviation is 0.55 Wm-2, corresponding to a relative standard deviation of 12%. For a case with partially absorbing aerosol with an aerosol optical depth of 0.2 and single scattering albedo of 0.8, the forcing changes to 1.04 Wm-2, and the standard deviation increases to 1.01 W-2, corresponding to a significant relative standard deviation of 97%. However, the top-of-atmosphere forcing variability owing to absorption (subtracting the scattering case from the case with scattering and absorption) is low, with absolute (relative) standard deviations of 0.45 Wm-2 (8%) clear-sky and 0.62 Wm-2 (11%) all-sky. Scaling the forcing standard deviation for a purely scattering case to match the sulfate radiative forcing in the AeroCom Direct Effect experiment demonstrates that host model uncertainties could explain about 36% of the overall sulfate forcing diversity of 0.11 Wm-2 in the AeroCom Direct Radiative Effect experiment. Host model errors in aerosol radiative forcing are largest in regions of uncertain host model components, such as stratocumulus cloud decks or areas with poorly constrained surface albedos, such as sea ice. Our results demonstrate that host model uncertainties are an important component of aerosol forcing uncertainty that require further attention.
Modeling the effects of urban vegetation on air pollution
David J. Nowak; Patrick J. McHale; Myriam Ibarra; Daniel Crane; Jack C. Stevens; Chris J. Luley
1998-01-01
Urban vegetation can directly and indirectly affect local and regional air quality by altering the urban atmospheric environment. Trees affect local air temperature by transpiring water through their leaves, by blocking solar radiation (tree shade), which reduces radiation absorption and heat storage by various anthropogenic surfaces (e.g., buildings, roads), and by...
The ability of a coupled meteorology–chemistry model, i.e., Weather Research and Forecast and Community Multiscale Air Quality (WRF-CMAQ), to reproduce the historical trend in aerosol optical depth (AOD) and clear-sky shortwave radiation (SWR) over the Northern Hemisphere h...
Quasi-analytical treatment of spatially averaged radiation transfer in complex terrain
NASA Astrophysics Data System (ADS)
LöWe, H.; Helbig, N.
2012-10-01
We provide a new quasi-analytical method to compute the subgrid topographic influences on the shortwave radiation fluxes and the effective albedo in complex terrain as required for large-scale meteorological, land surface, or climate models. We investigate radiative transfer in complex terrain via the radiosity equation on isotropic Gaussian random fields. Under controlled approximations we derive expressions for domain-averaged fluxes of direct, diffuse, and terrain radiation and the sky view factor. Domain-averaged quantities can be related to a type of level-crossing probability of the random field, which is approximated by long-standing results developed for acoustic scattering at ocean boundaries. This allows us to express all nonlocal horizon effects in terms of a local terrain parameter, namely, the mean-square slope. Emerging integrals are computed numerically, and fit formulas are given for practical purposes. As an implication of our approach, we provide an expression for the effective albedo of complex terrain in terms of the Sun elevation angle, mean-square slope, the area-averaged surface albedo, and the ratio of atmospheric direct beam to diffuse radiation. For demonstration we compute the decrease of the effective albedo relative to the area-averaged albedo in Switzerland for idealized snow-covered and clear-sky conditions at noon in winter. We find an average decrease of 5.8% and spatial patterns which originate from characteristics of the underlying relief. Limitations and possible generalizations of the method are discussed.
NASA Technical Reports Server (NTRS)
Wang, Sheng-Hsiang; Gautam, Ritesh; Lau, William K. M.; Tsay, Si-Chee; Sun, Wen-Yih; Kim, Kyu-Myong; Chern, Jiun-Dar; Hsu, Christina; Lin, Neng-Huei
2011-01-01
Current assessment of aerosol radiative effect is hindered by our incomplete knowledge of aerosol optical properties, especially absorption, and our current inability to quantify physical and microphysical processes. In this research, we investigate direct aerosol radiative effect over heavy aerosol loading areas (e.g., Indo-Gangetic Plains, South/East Asia) and its feedbacks on the South Asian climate during the pre-monsoon season (March-June) using the Purdue Regional Climate Model (PRCM) with prescribed aerosol data derived by the NASA Goddard Earth Observing System Model (GEOS-5). Our modeling domain covers South and East Asia (60-140E and 0-50N) with spatial resolutions of 45 km in horizontal and 28 layers in vertical. The model is integrated from 15 February to 30 June 2008 continuously without nudging (i.e., only forced by initial/boundary conditions). Two numerical experiments are conducted with and without the aerosol-radiation effects. Both simulations are successful in reproducing the synoptic patterns on seasonal-to-interannual time scales and capturing a pre-monsoon feature of the northward rainfall propagation over Indian region in early June which shown in Tropical Rainfall Measuring Mission (TRMM) observation. Preliminary result suggests aerosol-radiation interactions mainly alter surface-atmosphere energetics and further result in an adjustment of the vertical temperature distribution in lower atmosphere (below 700 hPa). The modifications of temperature and associated rainfall and circulation feedbacks on the regional climate will be discussed in the presentation.
Study of terahertz-radiation-induced DNA damage in human blood leukocytes
NASA Astrophysics Data System (ADS)
Angeluts, A. A.; Gapeyev, A. B.; Esaulkov, M. N.; Kosareva, O. G.; Matyunin, S. N.; Nazarov, M. M.; Pashovkin, T. N.; Solyankin, P. M.; Cherkasova, O. P.; Shkurinov, A. P.
2014-03-01
We have carried out the studies aimed at assessing the effect of terahertz radiation on DNA molecules in human blood leukocytes. Genotoxic testing of terahertz radiation was performed in three different oscillation regimes, the blood leukocytes from healthy donors being irradiated for 20 minutes with the mean intensity of 8 - 200 μW cm-2 within the frequency range of 0.1 - 6.5 THz. Using the comet assay it is shown that in the selected regimes such radiation does not induce a direct DNA damage in viable human blood leukocytes.
Testing of gallium arsenide solar cells on the CRRES vehicle
NASA Technical Reports Server (NTRS)
Trumble, T. M.
1985-01-01
A flight experiment was designed to determine the optimum design for gallium arsenide (GaAs) solar cell panels in a radiation environment. Elements of the experiment design include, different coverglass material and thicknesses, welded and soldered interconnects, different solar cell efficiencies, different solar cell types, and measurement of annealing properties. This experiment is scheduled to fly on the Combined Release and Radiation Effects Satellite (CRRES). This satellite will simultaneously measure the radiation environment and provide engineering data on solar cell degradation that can be directly related to radiation damage.
NASA Astrophysics Data System (ADS)
Kol'tsov, A. V.; Serov, Alexander V.
1995-03-01
A theoretical investigation is made of the time dependence of the spatial distribution of particles injected perpendicular to the direction of propagation of a linearly polarised inhomogeneous electromagnetic wave and reflected by this wave. It is shown that such reflection modulates the particle density in a beam which is homogeneous at injection. Stimulated emission of radiation from a ribbon electron beam reflected by a wave is considered. The spectral—angular and polarisation characteristics of such radiation are investigated.
Orientation of Space Station Freedom electrical power system in environmental effects assessment
NASA Technical Reports Server (NTRS)
Lu, Cheng-Yi
1990-01-01
The orientation effects of six Space Station Freedom Electrical Power System (EPS) components are evaluated for three environmental interactions: aerodynamic drag, atomic oxygen erosion, and orbital debris impact. Designers can directly apply these orientation factors to estimate the magnitude of the examined environment and the environmental effects for the EPS component of interest. The six EPS components are the solar array, photovoltaic module radiator, integrated equipment assembly, solar dynamic concentrator, solar dynamic radiator, and beta gimbal.
Magnetically focused liquid drop radiator
Botts, Thomas E.; Powell, James R.; Lenard, Roger
1986-01-01
A magnetically focused liquid drop radiator for application in rejecting rgy from a spacecraft, characterized by a magnetizable liquid or slurry disposed in operative relationship within the liquid droplet generator and its fluid delivery system, in combination with magnetic means disposed in operative relationship around a liquid droplet collector of the LDR. The magnetic means are effective to focus streams of droplets directed from the generator toward the collector, thereby to assure that essentially all of the droplets are directed into the collector, even though some of the streams may be misdirected as they leave the generator. The magnetic focusing means is also effective to suppress splashing of liquid when the droplets impinge on the collector.
Magnetically focused liquid drop radiator
Botts, T.E.; Powell, J.R.; Lenard, R.
1984-12-10
A magnetically focused liquid drop radiator for application in rejecting energy from a spacecraft, characterized by a magnetizable liquid or slurry disposed in operative relationship within the liquid droplet generator and its fluid delivery system, in combination with magnetic means disposed in operative relationship around a liquid droplet collector of the LDR. The magnetic means are effective to focus streams of droplets directed from the generator toward the collector, thereby to assure that essentially all of the droplets are directed into the collector, even though some of the streams may be misdirected as they leave the generator. The magnetic focusing means is also effective to suppress splashing of liquid when the droplets impinge on the collector.
Radiation area monitor device and method
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vencelj, Matjaz; Stowe, Ashley C.; Petrovic, Toni
A radiation area monitor device/method, utilizing: a radiation sensor having a directional radiation sensing capability; a rotation mechanism operable for selectively rotating the radiation sensor such that the directional radiation sensing capability selectively sweeps an area of interest; and a processor operable for analyzing and storing a radiation fingerprint acquired by the radiation sensor as the directional radiation sensing capability selectively sweeps the area of interest. Optionally, the radiation sensor includes a gamma and/or neutron radiation sensor. The device/method selectively operates in: a first supervised mode during which a baseline radiation fingerprint is acquired by the radiation sensor; and amore » second unsupervised mode during which a subsequent radiation fingerprint is acquired by the radiation sensor, wherein the subsequent radiation fingerprint is compared to the baseline radiation fingerprint and, if a predetermined difference threshold is exceeded, an alert is issued.« less
Origin of ΔN{sub eff} as a result of an interaction between dark radiation and dark matter
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bjaelde, Ole Eggers; Das, Subinoy; Moss, Adam, E-mail: oeb@phys.au.dk, E-mail: subinoy@physik.rwth-aachen.de, E-mail: Adam.Moss@nottingham.ac.uk
2012-10-01
Results from the Wilkinson Microwave Anisotropy Probe (WMAP), Atacama Cosmology Telescope (ACT) and recently from the South Pole Telescope (SPT) have indicated the possible existence of an extra radiation component in addition to the well known three neutrino species predicted by the Standard Model of particle physics. In this paper, we explore the possibility of the apparent extra dark radiation being linked directly to the physics of cold dark matter (CDM). In particular, we consider a generic scenario where dark radiation, as a result of an interaction, is produced directly by a fraction of the dark matter density effectively decayingmore » into dark radiation. At an early epoch when the dark matter density is negligible, as an obvious consequence, the density of dark radiation is also very small. As the Universe approaches matter radiation equality, the dark matter density starts to dominate thereby increasing the content of dark radiation and changing the expansion rate of the Universe. As this increase in dark radiation content happens naturally after Big Bang Nucleosynthesis (BBN), it can relax the possible tension with lower values of radiation degrees of freedom measured from light element abundances compared to that of the CMB. We numerically confront this scenario with WMAP+ACT and WMAP+SPT data and derive an upper limit on the allowed fraction of dark matter decaying into dark radiation.« less
NASA Astrophysics Data System (ADS)
Bates, T. S.; Anderson, T. L.; Baynard, T.; Bond, T.; Boucher, O.; Carmichael, G.; Clarke, A.; Erlick, C.; Guo, H.; Horowitz, L.; Howell, S.; Kulkarni, S.; Maring, H.; McComiskey, A.; Middlebrook, A.; Noone, K.; O'Dowd, C. D.; Ogren, J. A.; Penner, J.; Quinn, P. K.; Ravishankara, A. R.; Savoie, D. L.; Schwartz, S. E.; Shinozuka, Y.; Tang, Y.; Weber, R. J.; Wu, Y.
2005-12-01
The largest uncertainty in the radiative forcing of climate change over the industrial era is that due to aerosols, a substantial fraction of which is the uncertainty associated with scattering and absorption of shortwave (solar) radiation by anthropogenic aerosols in cloud-free conditions. Quantifying and reducing the uncertainty in aerosol influences on climate is critical to understanding climate change over the industrial period and to improving predictions of future climate change for assumed emission scenarios. Measurements of aerosol properties during major field campaigns in several regions of the globe during the past decade are contributing to an enhanced understanding of atmospheric aerosols and their effects on light scattering and climate. The present study, which focuses on three regions downwind of major urban/population centers (North Indian Ocean during INDOEX, the Northwest Pacific Ocean during ACE-Asia, and the Northwest Atlantic Ocean during ICARTT), incorporates understanding gained from field observations of aerosol distributions and properties into calculations of perturbations in radiative fluxes due to these aerosols. This study evaluates the current state of observations and of two chemical transport models (STEM and MOZART). Measurements of burdens, extinction optical depth, and direct radiative effect of aerosols (change in radiative flux due to total aerosols) are used as measurement-model check points to assess uncertainties. In-situ measured and remotely sensed aerosol properties for each region (mixing state, mass scattering efficiency, single scattering albedo, and angular scattering properties and their dependences on relative humidity) are used as input parameters to two radiative transfer models (GFDL and University of Michigan) to constrain estimates of aerosol radiative effects, with uncertainties in each step propagated through the analysis. Such comparisons with observations and resultant reductions in uncertainties are essential for improving and developing confidence in climate model calculations incorporating aerosol forcing.
The biological effects of space radiation during long stays in space.
Ohnishi, Ken; Ohnishi, Takeo
2004-12-01
Many space experiments are scheduled for the International Space Station (ISS). Completion of the ISS will soon become a reality. Astronauts will be exposed to low-level background components from space radiation including heavy ions and other high-linear energy transfer (LET) radiation. For long-term stay in space, we have to protect human health from space radiation. At the same time, we should recognize the maximum permissible doses of space radiation. In recent years, physical monitoring of space radiation has detected about 1 mSv per day. This value is almost 150 times higher than that on the surface of the Earth. However, the direct effects of space radiation on human health are currently unknown. Therefore, it is important to measure biological dosimetry to calculate relative biological effectiveness (RBE) for human health during long-term flight. The RBE is possibly modified by microgravity. In order to understand the exact RBE and any interaction with microgravity, the ISS centrifugation system will be a critical tool, and it is hoped that this system will be in operation as soon as possible.
Phylogenetic context determines the role of competition in adaptive radiation
Tan, Jiaqi; Slattery, Matthew R.; Yang, Xian; Jiang, Lin
2016-01-01
Understanding ecological mechanisms regulating the evolution of biodiversity is of much interest to ecologists and evolutionary biologists. Adaptive radiation constitutes an important evolutionary process that generates biodiversity. Competition has long been thought to influence adaptive radiation, but the directionality of its effect and associated mechanisms remain ambiguous. Here, we report a rigorous experimental test of the role of competition on adaptive radiation using the rapidly evolving bacterium Pseudomonas fluorescens SBW25 interacting with multiple bacterial species that differed in their phylogenetic distance to the diversifying bacterium. We showed that the inhibitive effect of competitors on the adaptive radiation of P. fluorescens decreased as their phylogenetic distance increased. To explain this phylogenetic dependency of adaptive radiation, we linked the phylogenetic distance between P. fluorescens and its competitors to their niche and competitive fitness differences. Competitive fitness differences, which showed weak phylogenetic signal, reduced P. fluorescens abundance and thus diversification, whereas phylogenetically conserved niche differences promoted diversification. These results demonstrate the context dependency of competitive effects on adaptive radiation, and highlight the importance of past evolutionary history for ongoing evolutionary processes. PMID:27335414
Damage Thresholds for Cultures RPE Cells Exposed to Lasers at 532 nm and 458 nm
2007-06-01
ADDRESS(ES) Air Force Research Laboratory H uman Effectiveness Directorate Directed Energy Bioeffects Division Optical Radiation Branch 2624 Louis Bauer Dr...Directed Energy Bioeffects Division Optical Radiation Branch 2624 Louis Bauer Dr. Brooks City-Base, TX 7 8235-5128 1 0. SPoNSOR/MON|TOR’S ACRONYM(S) AFRL...p t b m T a i b i fi d D o a T t i f e t A B r Journal of Biomedical Optics 123, 034030 May/June 2007 J amage thresholds for cultured retinal
Radiosensitization: enhancing the radiation inactivation of foodborne bacteria
NASA Astrophysics Data System (ADS)
Borsa, J.; Lacroix, M.; Ouattara, B.; Chiasson, F.
2004-09-01
Irradiation of meat products to kill pathogens can be limited by radiation-induced detriment of sensory quality. Since such detriment is directly related to dose, one approach to reduce it is by devising means to lower the dose of radiation required for processing. Increasing the radiation sensitivity of the target microorganisms would lower the dose required for a given level of microbial kill. In this work, the radiation sensitivities of inoculated Escherichia coli and Salmonella typhi in ground beef were examined under a variety of conditions. Results showed that specific manipulations of treatment conditions significantly increased the radiation sensitivity of the test organisms, ranging from a few percent to several-fold reduction in D10. In particular, radiation sensitization could be effected by certain additives, including carvacrol, thymol and trans-cinnamaldehyde, and also by certain compositions of modified atmosphere in the package headspace. A combination of additives and modified atmosphere effected a greater radiosensitization effect than could be achieved by either factor applied alone. Radiosensitization could be demonstrated with irradiation of either fresh or frozen ground meat. The radiosensitization phenomenon may be of practical utility in enhancing the technical effectiveness and feasibility of irradiation of a variety of meat and other food products.
NASA Astrophysics Data System (ADS)
Bates, T. S.; Anderson, T. L.; Baynard, T.; Bond, T.; Boucher, O.; Carmichael, G.; Clarke, A.; Erlick, C.; Guo, H.; Horowitz, L.; Howell, S.; Kulkarni, S.; Maring, H.; McComiskey, A.; Middlebrook, A.; Noone, K.; O'Dowd, C. D.; Ogren, J.; Penner, J.; Quinn, P. K.; Ravishankara, A. R.; Savoie, D. L.; Schwartz, S. E.; Shinozuka, Y.; Tang, Y.; Weber, R. J.; Wu, Y.
2006-01-01
The largest uncertainty in the radiative forcing of climate change over the industrial era is that due to aerosols, a substantial fraction of which is the uncertainty associated with scattering and absorption of shortwave (solar) radiation by anthropogenic aerosols in cloud-free conditions (IPCC, 2001). Quantifying and reducing the uncertainty in aerosol influences on climate is critical to understanding climate change over the industrial period and to improving predictions of future climate change for assumed emission scenarios. Measurements of aerosol properties during major field campaigns in several regions of the globe during the past decade are contributing to an enhanced understanding of atmospheric aerosols and their effects on light scattering and climate. The present study, which focuses on three regions downwind of major urban/population centers (North Indian Ocean (NIO) during INDOEX, the Northwest Pacific Ocean (NWP) during ACE-Asia, and the Northwest Atlantic Ocean (NWA) during ICARTT), incorporates understanding gained from field observations of aerosol distributions and properties into calculations of perturbations in radiative fluxes due to these aerosols. This study evaluates the current state of observations and of two chemical transport models (STEM and MOZART). Measurements of burdens, extinction optical depth (AOD), and direct radiative effect of aerosols (DRE - change in radiative flux due to total aerosols) are used as measurement-model check points to assess uncertainties. In-situ measured and remotely sensed aerosol properties for each region (mixing state, mass scattering efficiency, single scattering albedo, and angular scattering properties and their dependences on relative humidity) are used as input parameters to two radiative transfer models (GFDL and University of Michigan) to constrain estimates of aerosol radiative effects, with uncertainties in each step propagated through the analysis. Constraining the radiative transfer calculations by observational inputs increases the clear-sky, 24-h averaged AOD (34±8%), top of atmosphere (TOA) DRE (32±12%), and TOA direct climate forcing of aerosols (DCF - change in radiative flux due to anthropogenic aerosols) (37±7%) relative to values obtained with "a priori" parameterizations of aerosol loadings and properties (GFDL RTM). The resulting constrained TOA DCF is -3.3±0.47, -14±2.6, -6.4±2.1 Wm-2 for the NIO, NWP, and NWA, respectively. Constraining the radiative transfer calculations by observational inputs reduces the uncertainty range in the DCF in these regions relative to global IPCC (2001) estimates by a factor of approximately 2. Such comparisons with observations and resultant reductions in uncertainties are essential for improving and developing confidence in climate model calculations incorporating aerosol forcing.
The generation of gravitational waves. 1. Weak-field sources: A plug-in-and-grind formalism
NASA Technical Reports Server (NTRS)
Thorne, K. S.; Kovacs, S. J.
1974-01-01
A plug-in-and-grind formalism is derived for calculating the gravitational waves emitted by any system with weak internal gravitational fields. If the internal fields have negligible influence on the system's motions, then the formalism reduces to standard linearized theory. Whether or not gravity affects the motions, if the motions are slow and internal stresses are weak, then the new formalism reduces to the standard quadrupole-moment formalism. In the general case the new formalism expresses the radiation in terms of a retarded Green's function for slightly curved spacetime, and then breaks the Green's-function integral into five easily understood pieces: direct radiation, produced directly by the motions of the sources; whump radiation, produced by the the gravitational stresses of the source; transition radiation, produced by a time-changing time delay (Shapiro effect) in the propagation of the nonradiative, 1/r field of the source; focussing radiation produced when one portion of the source focusses, in a time-dependent way, the nonradiative field of another portion of the source, and tail radiation, produced by backscatter of the nonradiative field in regions of focussing.
Model atmospheres and radiation of magnetic neutron stars: Anisotropic thermal emission
NASA Technical Reports Server (NTRS)
Pavlov, G. G.; Shibanov, Yu. A.; Ventura, J.; Zavlin, V. E.
1994-01-01
We investigate the anisotropy of the thermal radiation emitted by a surface element of a neutron star atmosphere (e.g., by a polar cap of a radio pulsar). Angular dependences of the partial fluxes at various photon energies, and spectra at various angles are obtained for different values of the effective temperature T(sub eff) and magnetic field strength B, and for different directions of the magnetic field. It is shown that the local radiation of the magnetized neutron star atmospheres is highly anisotropic, with the maximum flux emitted in the magnetic field direction. At high B the angular dependences in the soft X-ray range have two maxima, a high narrow peak along B and a lower and broader maximum at intermediate angles. The radiation is strongly polarized, the modulation of the degree of polarization due to the rotation of the neurtron star may be much higher than that for the radiative flux. The results obtained are compared with recent ROSAT observations of the thermal-like radiation from the radio pulsars PSR 1929+10 and PSR J0437-4715.
Exploring the observational constraints on the simulation of brown carbon
NASA Astrophysics Data System (ADS)
Wang, Xuan; Heald, Colette L.; Liu, Jiumeng; Weber, Rodney J.; Campuzano-Jost, Pedro; Jimenez, Jose L.; Schwarz, Joshua P.; Perring, Anne E.
2018-01-01
Organic aerosols (OA) that strongly absorb solar radiation in the near-UV are referred to as brown carbon (BrC). The sources, evolution, and optical properties of BrC remain highly uncertain and contribute significantly to uncertainty in the estimate of the global direct radiative effect (DRE) of aerosols. Previous modeling studies of BrC optical properties and DRE have been unable to fully evaluate model performance due to the lack of direct measurements of BrC absorption. In this study, we develop a global model simulation (GEOS-Chem) of BrC and test it against BrC absorption measurements from two aircraft campaigns in the continental US (SEAC4RS and DC3). To the best of our knowledge, this is the first study to compare simulated BrC absorption with direct aircraft measurements. We show that BrC absorption properties estimated based on previous laboratory measurements agree with the aircraft measurements of freshly emitted BrC absorption but overestimate aged BrC absorption. In addition, applying a photochemical scheme to simulate bleaching/degradation of BrC improves model skill. The airborne observations are therefore consistent with a mass absorption coefficient (MAC) of freshly emitted biomass burning OA of 1.33 m2 g-1 at 365 nm coupled with a 1-day whitening e-folding time. Using the GEOS-Chem chemical transport model integrated with the RRTMG radiative transfer model, we estimate that the top-of-the-atmosphere all-sky direct radiative effect (DRE) of OA is -0.344 Wm-2, 10 % higher than that without consideration of BrC absorption. Therefore, our best estimate of the absorption DRE of BrC is +0.048 Wm-2. We suggest that the DRE of BrC has been overestimated previously due to the lack of observational constraints from direct measurements and omission of the effects of photochemical whitening.
Rew, Soo-Jung; Lee, Du-Hyeon; Park, Chang-Hwan; Jeon, Jin; Kim, Hyun-Soo; Choi, Sung-Kyu; Rew, Jong-Sun
2016-09-01
Endoscopic retrograde biliary drainage (ERBD) has become a standard procedure in patients with a biliary obstruction. Intraductal ultrasonography (IDUS) has emerged as a new tool for managing extrahepatic biliary diseases. IDUS-directed ERBD can be performed without conventional cholangiography (CC). The goal of this study was to assess the effectiveness and safety of IDUS-directed ERBD compared to CC-directed ERBD in patients with an extrahepatic biliary obstruction. A total of 210 patients who had undergone IDUS-directed ERBD (IDUS-ERBD, n = 105) and CC-directed ERBD (CC-ERBD, n = 105) between October 2013 and April 2014 were analyzed retrospectively. The primary outcome measure was the procedural success rate. Secondary outcome measures included clinical outcomes, total procedure time, radiation exposure time, and overall complication rates. The total technical success rate of ERBD was 100% (105/105) in the IDUS-ERBD and CC-ERBD groups. Mean procedure time was slightly prolonged in the IDUS-ERBD group than that in the CC-ERBD group (32.1 ± 9.9 minutes vs. 28.4 ± 11.6 minutes, p = 0.023). Mean radiation exposure time was one-third less in the IDUS-ERBD group than that in the CC-ERBD group (28.0 ± 49.3 seconds vs. 94.2 ± 57.3 seconds, p < 0.001). No significant differences in complication rates were detected between the groups. IDUS-ERBD was equally effective and safe as CC-ERBD in patients with an extrahepatic biliary obstruction. Although IDUS-ERBD increased total procedure time, it significantly decreased radiation exposure.
Solar radiation on Mars: Update 1990
NASA Technical Reports Server (NTRS)
Appelbaum, Joseph; Flood, Dennis J.
1990-01-01
Detailed information on solar radiation characteristics on Mars are necessary for effective design of future planned solar energy systems operating on the surface of Mars. The authors present a procedure and solar radiation related data from which the diurnally and daily variation of the global, direct beam and diffuse insolation on Mars are calculated. The radiation data are based on measured optical depth of the Martian atmosphere derived from images taken of the Sun with a special diode on the Viking Lander cameras and computation based on multiple wavelength and multiple scattering of the solar radiation. This work is an update to NASA-TM-102299 and includes a refinement of the solar radiation model.
In situ study on surface roughening in radiation-resistant Ag nanowires
NASA Astrophysics Data System (ADS)
Shang, Z.; Li, Jin; Fan, C.; Chen, Y.; Li, Q.; Wang, H.; Shen, T. D.; Zhang, X.
2018-05-01
Metallic materials subjected to heavy ion irradiation experience significant radiation damage. Free surface is a type of effective defect sinks to improve the radiation resistance in metallic materials. However, the radiation resistance of metallic nanowires (NWs) is largely unknown. Here we show, via in situ Kr ion irradiations in a transmission electron microscope, Ag NWs exhibited much better radiation resistance than coarse-grained Ag. Irradiation-induced prominent surface roughening in Ag NWs provides direct evidence for interaction between defect clusters and free surface. Diameter dependent variation of the surface roughness in irradiated Ag NWs has also been observed. This study provides insight on mechanisms of enhanced radiation resistance via free surfaces in metallic NWs.
In situ study on surface roughening in radiation-resistant Ag nanowires.
Shang, Z; Li, Jin; Fan, C; Chen, Y; Li, Q; Wang, H; Shen, T D; Zhang, X
2018-05-25
Metallic materials subjected to heavy ion irradiation experience significant radiation damage. Free surface is a type of effective defect sinks to improve the radiation resistance in metallic materials. However, the radiation resistance of metallic nanowires (NWs) is largely unknown. Here we show, via in situ Kr ion irradiations in a transmission electron microscope, Ag NWs exhibited much better radiation resistance than coarse-grained Ag. Irradiation-induced prominent surface roughening in Ag NWs provides direct evidence for interaction between defect clusters and free surface. Diameter dependent variation of the surface roughness in irradiated Ag NWs has also been observed. This study provides insight on mechanisms of enhanced radiation resistance via free surfaces in metallic NWs.
A diagnostic technique used to obtain cross range radiation centers from antenna patterns
NASA Technical Reports Server (NTRS)
Lee, T. H.; Burnside, W. D.
1988-01-01
A diagnostic technique to obtain cross range radiation centers based on antenna radiation patterns is presented. This method is similar to the synthetic aperture processing of scattered fields in the radar application. Coherent processing of the radiated fields is used to determine the various radiation centers associated with the far-zone pattern of an antenna for a given radiation direction. This technique can be used to identify an unexpected radiation center that creates an undesired effect in a pattern; on the other hand, it can improve a numerical simulation of the pattern by identifying other significant mechanisms. Cross range results for two 8' reflector antennas are presented to illustrate as well as validate that technique.
NASA Astrophysics Data System (ADS)
Brown, Hunter Y.
A recent development in the representation of aerosols in climate models is the realization that some components of organic carbon (OC), emitted from biomass and biofuel burning, can have a significant contribution to short-wave radiation absorption in the atmosphere. The absorbing fraction of OC is referred to as brown carbon (BrC). This study introduces one of the first implementations of BrC into the Community Earth System Model (CESM), using a parameterization for BrC absorption described in Saleh et al. (2014). 9-year experiments are run (2003-2011) with prescribed emissions and sea surface temperatures to analyze the effect of BrC in the atmosphere. Model validation is conducted via model comparison to single-scatter albedo (SSA) and aerosol optical depth from the Aerosol Robotic Network (AERONET), as well as comparison with a laboratory derived parameterization for SSA dependent on the (black carbon (BC))/(BC+OC) ratio in biomass burning emissions. These comparisons reveal a model underestimation of SSA in biomass burning regions for both default and BrC model runs. Global annual average radiative effects are calculated due to aerosol-radiation interactions (REari; 0.13+/-0.021 W m -2), aerosol-cloud interactions (REaci; 0.07+/-0.056 W m -2), and surface albedo change (REsac; -0.06+/-0.035 W m -2). REari is similar to other studies' estimations of BrC direct radiative effect, while REaci indicates a global reduction in low clouds due to the BrC semi-direct effect. REsac suggests increased surface albedo with BrC implementation due to modified snowfall, but does not take into account the warming effect of BrC on snow. Lastly, comparisons of BrC implementation approaches find that this implementation may do a better job of estimating BrC radiative effect in the Arctic regions than previous studies with CESM.
Climate-chemical interactions and greenhouse effects of trace gases
NASA Technical Reports Server (NTRS)
Shi, Guang-Yu; Fan, Xiao-Biao
1994-01-01
A completely coupled one-dimensional radiative-convective (RC) and photochemical-diffusion (PC) model has been developed recently and used to study the climate-chemical interactions. The importance of radiative-chemical interactions within the troposphere and stratosphere has been examined in some detail. We find that increases of radiatively and/or chemically active trace gases such as CO2, CH4 and N2O have both the direct effects and the indirect effects on climate change by changing the atmospheric O3 profile through their interaction with chemical processes in the atmosphere. It is also found that the climatic effect of ozone depends strongly on its vertical distribution throughout the troposphere and stratosphere, as well on its column amount in the atmosphere.
Lorimore, S A; Wright, E G
2003-01-01
To review studies of radiation responses in the haemopoietic system in the context of radiation-induced genomic instability, bystander effects and inflammatory-type processes. There is considerable evidence that cells that themselves are not exposed to ionizing radiation but are the progeny of cells irradiated many cell divisions previously may express a high frequency of gene mutations, chromosomal aberrations and cell death. These effects are collectively known as radiation-induced genomic instability. A second untargeted effect results in non-irradiated cells exhibiting responses typically associated with direct radiation exposure but occurs as a consequence of contact with irradiated cells or by receiving soluble signals from irradiated cells. These effects are collectively known as radiation-induced bystander effects. Reported effects include increases or decreases in damage-inducible and stress-related proteins; increases or decreases in reactive oxygen species, cell death or cell proliferation, and induction of mutations and chromosome aberrations. This array of responses is reminiscent of effects mediated by cytokines and other similar regulatory factors that may involve, but do not necessarily require, gap junction-mediated transfer, have multiple inducers and a variety of context-dependent consequences in different cell systems. That chromosomal instability in haemopoietic cells can be induced by an indirect bystander-type mechanism both in vitro and in vivo provides a potential link between these two untargeted effects and there are radiation responses in vivo consistent with the microenvironment contributing secondary cell damage as a consequence of an inflammatory-type response to radiation-induced injury. Intercellular signalling, production of cytokines and free radicals are features of inflammatory responses that have the potential for both bystander-mediated and persisting damage as well as for conferring a predisposition to malignancy. The induction of bystander effects and instabilities may reflect interrelated aspects of a non-specific inflammatory-type response to radiation-induced stress and injury and be involved in a variety of the pathological consequences of radiation exposures.
Correction of broadband albedo measurements affected by unknown slope and sensor tilts
NASA Astrophysics Data System (ADS)
Weiser, Ursula; Olefs, Marc; Schöner, Wolfgang; Weyss, Gernot; Hynek, Bernhard
2017-02-01
Geometric effects induced by the underlying terrain slope or by tilt errors of radiation sensors lead to an erroneous measurement of snow or ice albedo. Consequently, diurnal albedo variations are observed. A general method to correct tilt errors of albedo measurements in cases where tilts of both the sensors and the slopes are not accurately measured or known is presented. Atmospheric parameters for this correction method can either be taken from a nearby well-maintained and horizontally levelled measurement of global radiation or alternatively from a solar radiation model. In a next step the model is fitted to the measured data to determine tilts and directions of the sensors and the underlying terrain slope. This then allows to correct the measured albedo, the radiative balance and the energy balance. Depending on the direction of the slope and the sensors a comparison between measured and corrected albedo values reveals obvious over-or underestimations of albedo.
Using Radiative Signatures to Diagnose the Cause of Warming Associated with the Californian Drought
NASA Astrophysics Data System (ADS)
Wolf, S.; Yin, D.; Roderick, M. L.
2016-12-01
California recently experienced among the worst droughts of the last century, with unprecedented precipitation deficits and record high temperatures. The dry conditions caused severe water shortages in one of the economically most important agricultural regions of the US, particularly in the Central Valley. It has been hypothesized that anthropogenic warming is increasing the likelihood of such extreme droughts in California, or more specifically, that these drought conditions are a consequence of warmer temperatures from the enhanced greenhouse effect. Process studies suggest, however, that increased temperatures during droughts are mostly a consequence of reduced evaporative cooling resulting from the reduction in precipitation. Here we use surface radiation components from NASA's Clouds and Earth's Radiant Energy Systems (CERES), climatic data and direct flux tower measurements to investigate the cause of warming associated with the recent Californian Drought. Based on radiative signatures and surface energy balance we show that the warmer temperatures were not associated with an enhanced greenhouse effect by anthropogenic warming. The radiative signature showed decreased longwave downward radiation during the water years 2013-2014 compared to the decadal mean of 2001-2012. Instead, increased solar downward radiation in combination with reduced evaporative cooling from water deficits enhanced surface temperatures and sensible heat transfer to the atmosphere. We conclude that the drought was not directly associated with warming by increased longwave downward radiation, and that there is no simple relation between warmer surface temperatures and drought.
Recent progress in the transition radiation detector techniques
NASA Technical Reports Server (NTRS)
Yuan, L. C. L.
1973-01-01
A list of some of the major experimental achievements involving charged particles in the relativistic region are presented. With the emphasis mainly directed to the X-ray region, certain modes of application of the transition radiation for the identification and separation of relativistic charged particles are discussed. Some recent developments in detection techniques and improvements in detector performances are presented. Experiments were also carried out to detect the dynamic radiation, but no evidence of such an effect was observed.
Response of heterogeneous vegetation to aerosol radiative forcing over a northeast Indian station.
Latha, R; Vinayak, B; Murthy, B S
2018-01-15
Importance of atmospheric aerosols through direct and indirect effects on hydrological cycle is highlighted through multiple studies. This study tries to find how much the aerosols can affect evapo-transpiration (ET), a key component of the hydrological cycle over high NDVI (normalized difference vegetation index)/dense canopy, over Dibrugarh, known for vast tea plantation. The radiative effects of aerosols are calculated using satellite (Terra-MODIS) and reanalysis data on daily and monthly scales. Aerosol optical depth (AOD) obtained from satellite and ground observations compares well. Aerosol radiative forcing (ARF), calculated using MERRA data sets of 'clean-clear radiation' and 'clear-radiation' at the surface, shows a lower forcing efficiency, 35 Wm -zs , that is about half of that of ground observations. As vegetation controls ET over high NDVI area to the maximum and that gets modified through ARF, a regression equation is fitted between ET, AOD and NDVI for this station as ET = 0.25 + (-84.27) × AOD + (131.51) × NDVI that explains 82% of 'daily' ET variation using easily available satellite data. ET is found to follow net radiation closely and the direct relation between soil moisture and ET is weak on daily scale over this station as it may be acting through NDVI. Copyright © 2017 Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ong, S.G.
1964-01-01
At high altitude (3,130 m) tuberculous mice exposed to cosmic radiation under 10 cm of lead showed significantly greater mean survival time and a significantly greater number of survivors than tuberculous mice exposed to direct cosmic radiation. Tuberculous mice exposed to cosmic radiation at high altitude under 10 cm of lead showed a significantly greater mean survival time than tuberculous mice kept at sea level, exposed to direct cosmic radiation, and to cosmic radiation under 1, 2, and 10 cm of lead. The correlation analysis shows that a decreas in lung lesions is associated with an increase in survival time.more » The decrease in lung lesions is associated with an enlargement of the spleen. At high altitude the female showed a significantly greater number of survivors than the male. At sea level no significant difference was observed. On the average the female showed a significantly greater number of survivors. The beneficial effect of daylight with ultraviolet light on tuberculous mice was manifested in a lower maximum of mortality and in a significant decrease of lung and spleen lesions. (auth)« less
Radiative effects during the assembly of direct collapse black holes
NASA Astrophysics Data System (ADS)
Smith, Aaron; Becerra, Fernando; Bromm, Volker; Hernquist, Lars
2017-11-01
We perform a post-processing radiative feedback analysis on a 3D ab initio cosmological simulation of an atomic cooling halo under the direct collapse black hole (DCBH) scenario. We maintain the spatial resolution of the simulation by incorporating native ray-tracing on unstructured mesh data, including Monte Carlo Lyman α (Ly α) radiative transfer. DCBHs are born in gas-rich, metal-poor environments with the possibility of Compton-thick conditions, NH ≳ 1024 cm-2. Therefore, the surrounding gas is capable of experiencing the full impact of the bottled-up radiation pressure. In particular, we find that multiple scattering of Ly α photons provides an important source of mechanical feedback after the gas in the sub-parsec region becomes partially ionized, avoiding the bottleneck of destruction via the two-photon emission mechanism. We provide detailed discussion of the simulation environment, expansion of the ionization front, emission and escape of Ly α radiation, and Compton scattering. A sink particle prescription allows us to extract approximate limits on the post-formation evolution of the radiative feedback. Fully coupled Ly α radiation hydrodynamics will be crucial to consider in future DCBH simulations.
Je, Yub; Lee, Haksue; Park, Jongkyu; Moon, Wonkyu
2010-06-01
An ultrasonic radiator is developed to generate a difference frequency sound from two frequencies of ultrasound in air with a parametric array. A design method is proposed for an ultrasonic radiator capable of generating highly directive, high-amplitude ultrasonic sound beams at two different frequencies in air based on a modification of the stepped-plate ultrasonic radiator. The stepped-plate ultrasonic radiator was introduced by Gallego-Juarez et al. [Ultrasonics 16, 267-271 (1978)] in their previous study and can effectively generate highly directive, large-amplitude ultrasonic sounds in air, but only at a single frequency. Because parametric array sources must be able to generate sounds at more than one frequency, a design modification is crucial to the application of a stepped-plate ultrasonic radiator as a parametric array source in air. The aforementioned method was employed to design a parametric radiator for use in air. A prototype of this design was constructed and tested to determine whether it could successfully generate a difference frequency sound with a parametric array. The results confirmed that the proposed single small-area transducer was suitable as a parametric radiator in air.
NASA Astrophysics Data System (ADS)
Wang, Sheng; Ibrom, Andreas; Pilegaard, Kim; Bauer-Gottwein, Peter; Garcia, Monica
2017-04-01
Ecosystem carbon and water fluxes are controlled by the interplay of biophysical factors such as solar radiation, temperature and soil moisture. In high latitudes, cloudy days are prevalent with a low amount of solar radiation and a higher proportion of diffuse radiation. For instance, in Denmark 90% of all days are non-clear (fraction of direct radiation < 50%). Changes in cloud cover related with climate change are considered the major source of uncertainty in our understanding of the Earth's climate sensitivity to increased atmospheric CO2 (Brown, 2016). It is also unknown how ecosystems will respond to potential changes in the proportion of diffuse/direct radiation, which can modify the coupled photosynthesis and transpiration rates in future. This study aims to evaluate effects of diffuse radiation on the ecosystem carbon and water fluxes in a temperate deciduous forest using long term eddy covariance observations. Eddy covariance records (Gross Primary Productivity: GPP; Evapotranspiration: ET) from 2002 to 2012, field data, Normalized Difference Vegetation Index (NDVI) from Moderate Resolution Imaging Spectroradiometer (MODIS), and sap flow data during the period of 2009-2011 at Sorø, a Danish beech forest flux site, were used for analysis. A Cloudiness Index (CI), which is based on actual and potential shortwave incoming radiation and can indicate the proportion of diffuse radiation, was used. First, multiple regression based path analysis was applied to daily and monthly observations to partition direct and indirect effects from CI to GPP and ET. Results indicate diffuse radiation increases the light use efficiency (LUE) with CI being as important as other constraints, e.g. air temperature (Tair), vapor pressure deficit (VPD) and Photosynthetically Active Radiation (PAR), on regulating LUE. An increase of the CI value of 0.1 can increase maximum LUE by about 0.286 gC•MJ-1. Following PAR and LAI, CI has the third largest effects on GPP. For ET, path analysis showed the impact of CI is limited. Further, the CI constraint was added to two physiologically based models for estimating GPP (LUE, Potter et al., 1993) and ET (Priestley-Taylor Jet Propulsion Laboratory, PT-JPL, Fisher et al., 2008) at the daily time scale to assess model improvement. When considering the effect of diffuse radiation by including the CI constraint, the RMSE of the simulated GPP decreases from 2.12 to 1.42 gC•day-1. The performance of PT-JPL improves slightly with RMSE decreasing from 17.92 to 15.51 W•m-2. The sap flow data, which indicates the transpiration, has a higher correlation with the simulated transpiration with CI (0.84) than without CI (0.81). Using these two models (LUE and PT-JPL), the Sobol global sensitivity method was applied to quantify the contribution of CI and its interactions with other forcing variables to the variability of GPP and ET. CI contributes to 23.5% of GPP variation and 4.5% of transpiration variation during summer. This study highlights how important it is to consider diffuse radiation to simulate the coupled carbon and water processes in land surface modeling schemes.
Yanfei Guo; Michael G. Shelton
2004-01-01
We used modified shadehouses to simulate the complex light conditions within forest openings and tested the effects of time of direct light exposure, the ratio of direct light to day length, and daily photosynthetically active radiation on aboveground biomass and morphological characteristics of 2-year-old cherrybark oak (Quercus pagoda Raf.)...
Infrared radiation and inversion population of CO2 laser levels in Venusian and Martian atmospheres
NASA Technical Reports Server (NTRS)
Gordiyets, B. F.; Panchenko, V. Y.
1983-01-01
Formation mechanisms of nonequilibrium 10 micron CO2 molecule radiation and the possible existence of a natural laser effect in the upper atmospheres of Venus and Mars are theoretically studied. An analysis is made of the excitation process of CO2 molecule vibrational-band levels (with natural isotropic content) induced by direct solar radiation in bands 10.6, 9.4, 4.3, 2.7 and 2.0 microns. The model of partial vibrational-band temperatures was used in the case. The problem of IR radiation transfer in vibrational-rotational bands was solved in the radiation escape approximation.
An MDOE Assessment of Nozzle Vanes for High Bypass Ratio Jet Noise Reduction
NASA Technical Reports Server (NTRS)
Henderson, Brenda; Norum, Thomas; Bridges, James
2006-01-01
The effect of airfoil-shaped vanes placed in the fan stream of a BPR 8 coannular nozzle model system on the resulting jet noise was investigated. The experiments used a Modern Design of Experiments approach to investigate the impact of a range of vane parameters on the noise reduction achieved at representative takeoff conditions. The experimental results showed that the installation of the vanes decreased low frequency noise radiation in the downstream peak-noise direction and increased high frequency noise in the upstream direction. Results also showed that improper selection of the vane configuration resulted in increased low frequency noise radiation in the upstream direction. Large angles of attack are shown to reduce noise near the peak jet noise angle and increase noise in the upstream direction. The MDOE analysis yields an optimum design that minimizes perceived noise levels. Limited data taken with a BPR 5 nozzle system showed that the vanes result in better effective perceived noise reduction for lower bypass ratio nozzles than for the BPR 8 model.
NASA Astrophysics Data System (ADS)
Wang, Wei; Sun, Yeqing; Zhao, Qian; Han, Lu
2016-07-01
Highly ionizing radiation (HZE) in space is considered as main factor causing biological effects. Radiobiological studies during space flights are unrepeatable due to the variable space radiation environment, ground-base ion radiations are usually performed to simulate of the space biological effect. Spaceflights present a low-dose rate (0.1˜~0.3mGy/day) radiation environment inside aerocrafts while ground-base ion radiations present a much higher dose rate (100˜~500mGy/min). Whether ground-base ion radiation can reflect effects of space radiation is worth of evaluation. In this research, we compared the functional proteomic profiles of rice plants between on-ground simulated HZE particle radiation and spaceflight treatments. Three independent ground-base seed ionizing radiation experiments with different cumulative doses (dose range: 2˜~20000mGy) and different liner energy transfer (LET) values (13.3˜~500keV/μμm) and two independent seed spaceflight experiments onboard Chinese 20th satellite and SZ-6 spacecraft were carried out. Alterations in the proteome were analyzed by two-dimensional difference gel electrophoresis (2-D DIGE) with MALDI-TOF/TOF mass spectrometry identifications. 45 and 59 proteins showed significant (p<0.05) and reproducible quantitative differences in ground-base ion radiation and spaceflight experiments respectively. The functions of ground-base radiation and spaceflight proteins were both involved in a wide range of biological processes. Gene Ontology enrichment analysis further revealed that ground-base radiation responsive proteins were mainly involved in removal of superoxide radicals, defense response to stimulus and photosynthesis, while spaceflight responsive proteins mainly participate in nucleoside metabolic process, protein folding and phosphorylation. The results implied that ground-base radiations cannot truly reflect effects of spaceflight radiations, ground-base radiation was a kind of indirect effect to rice causing oxidation and metabolism stresses, but space radiation was a kind of direct effect leading to macromolecule (DNA and protein) damage and signal pathway disorders. This functional proteomic analysis work might provide a new evaluation method for further on-ground simulated HZE radiation experiments.
Necrostatin-1 rescues mice from lethal irradiation.
Huang, Zhentai; Epperly, Michael; Watkins, Simon C; Greenberger, Joel S; Kagan, Valerian E; Bayır, Hülya
2016-04-01
There is an emerging need in new medical products that can mitigate and/or treat the short- and long-term consequences of radiation exposure after a radiological or nuclear terroristic event. The direct effects of ionizing radiation are realized primarily via apoptotic death pathways in rapidly proliferating cells within the initial 1-2days after the exposure. However later in the course of the radiation disease necrotic cell death may ensue via direct and indirect pathways from increased generation of pro-inflammatory cytokines. Here we evaluated radiomitigative potential of necrostatin-1 after total body irradiation (TBI) and the contribution of necroptosis to cell death induced by radiation. Circulating TNFα levels were increased starting on d1 after TBI and associated with increased plasmalemma permeability in ileum of irradiated mice. Necrostatin-1 given iv. 48h after 9.5Gy TBI attenuated radiation-induced receptor interacting protein kinase 3 (RIPK3) serine phosphorylation in ileum and improved survival vs. vehicle. Utilizing apoptosis resistant cytochrome c(-/-) cells, we showed that radiation can induce necroptosis, which is attenuated by RNAi knock down of RIPK1 and RIPK3 or by treatment with necrostatin-1 or -1s whereas 1-methyl-L-tryptophan, an indoleamine-2,3-dioxygenase inhibitor, did not exhibit radiomitigative effect. This suggests that the beneficial effect of necrostatin-1 is likely through inhibition of RIPK1-mediated necroptotic pathway. Overall, our data indicate that necroptosis, a form of programmed necrosis, may play a significant role in cell death contributing to radiation disease and mortality. This study provides a proof of principle that necrostatin-1 and perhaps other RIPK1 inhibitors are promising therapeutic agents for radiomitigation after TBI. Copyright © 2016 Elsevier B.V. All rights reserved.
Plasma effect on weld pool surface reconstruction by shape-from-polarization analysis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Coniglio, N.; Mathieu, A., E-mail: alexandre.mathieu@u-bourgogne.fr; Aubreton, O.
2014-03-31
The polarimetric state of the thermal radiations emitted by the weld metal contains geometric information about the emitting surface. Even though the analysed thermal radiation has a wavelength corresponding to a blind spectral window of the arc plasma, the physical presence of the arc plasma itself interferes with the rays radiated by the weld pool surface before attaining the polarimeter, thus modifying the geometric information transported by the ray. In the present work, the effect of the arc plasma-surrounding zone on the polarimetric state and propagation direction of the radiated ray is analyzed. The interaction with the arc plasma zonemore » induces a drop in ray intensity and a refraction of ray optical path.« less
Radiation-induced bystander effect and adaptive response in mammalian cells
NASA Technical Reports Server (NTRS)
Zhou, H.; Randers-Pehrson, G.; Waldren, C. A.; Hei, T. K.
2004-01-01
Two conflicting phenomena, bystander effect and adaptive response, are important in determining the biological responses at low doses of radiation and have the potential to impact the shape of the dose-response relationship. Using the Columbia University charged-particle microbeam and the highly sensitive AL cell mutagenic assay, we show here that non-irradiated cells acquire mutagenesis through direct contact with cells whose nuclei have been traversed with a single alpha particle each. Pretreatment of cells with a low dose of X-rays four hours before alpha particle irradiation significantly decreased this bystander mutagenic response. Results from the present study address some of the fundamental issues regarding both the actual target and radiation dose effect and can contribute to our current understanding in radiation risk assessment. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.
Effects of radiation quality, intensity, and duration on photosynthesis and growth
NASA Technical Reports Server (NTRS)
Bugbee, Bruce
1994-01-01
Differences in radiation quality from the six most common electric lamps have little effect on photosynthetic rate. Radiation quality primarily alters growth because of changes in branching or internode elongation, which change radiation absorption. Growth and yield in wheat appear to be insensitive to radiation quality. Growth and yield in soybeans can be slightly increased under high pressure sodium (HPS) lamps compared to metal halide lamps, in spite of greatly reduced chlorophyll concentrations under HPS lamps. Daily integrated photosynthetic photon flux (mol m(exp -2)d(exp -1)) most directly determines leaf anatomy and growth. Photosynthetic photon flux (PPF) levels of 800 (mu)mol m(exp -2)s(exp -1) are adequate to simulate field daily-integrated PPF levels for both short and long day plants, but plant canopies can benefit from much higher PPF levels.
Effects of radiation quality, intensity, and duration on photosynthesis and growth
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bugbee, B.
1994-12-31
Differences in radiation quality from the six most common electric lamps have little effect on photosynthetic rate. Radiation quality primarily alters growth because of changes in branching or internode elongation, which change radiation absorption. Growth and yield in wheat appear to be insensitive to radiation quality. Growth and yield in soybeans can be slightly increased under high pressure sodium lamps compared to metal halide lamps, in spite of greatly reduced chlorophyll concentrations under HPS lamps. Daily integrated photosynthetic photon flux (mol m{sup -2} d{sup -1}) most directly determines leaf anatomy and growth. Photosynthetic photon flux levels of 800 {mu}mol m{supmore » -2} s{sup -1} are adequate to simulate field daily-integrated PPF levels for both short and long day plants, but plant canopies can benefit from much higher PPF levels.« less
Estimating the Longwave Radiation Underneath the Forest Canopy in Snow-dominated Setting
NASA Astrophysics Data System (ADS)
Zhou, Y.; Kumar, M.; Link, T. E.
2017-12-01
Forest canopies alter incoming longwave radiation at the land surface, thus influencing snow cover energetics. The snow surface receives longwave radiation from the sky as well as from surrounding vegetation. The longwave radiation from trees is determined by its skin temperature, which shows significant heterogeneity depending on its position and morphometric attributes. Here our goal is to derive an effective tree temperature that can be used to estimate the longwave radiation received by the land surface pixel. To this end, we implement these three steps: 1) derive a relation between tree trunk surface temperature and the incident longwave radiation, shortwave radiation, and air temperature; 2) develop an inverse model to calculate the effective temperature by establishing a relationship between the effective temperature and the actual tree temperature; and 3) estimate the effective temperature using widely measured variables, such as solar radiation and forest density. Data used to derive aforementioned relations were obtained at the University of Idaho Experimental Forest, in northern Idaho. Tree skin temperature, incoming longwave radiation, solar radiation received by the tree surface, and air temperature were measured at an isolated tree and a tree within a homogeneous forest stand. Longwave radiation received by the land surface and the sky view factors were also measured at the same two locations. The calculated effective temperature was then compared with the measured tree trunk surface temperature. Additional longwave radiation measurements with pyrgeometer arrays were conducted under forests with different densities to evaluate the relationship between effective temperature and forest density. Our preliminary results show that when exposed to direct shortwave radiation, the tree surface temperature shows a significant difference from the air temperature. Under cloudy or shaded conditions, the tree surface temperature closely follows the air temperature. The effective tree temperature follows the air temperature in a dense forest stand, although it is significantly larger than the air temperature near the isolated tree. This discrepancy motivates us to explore ways to represent the effective tree temperature for stands with different densities.
NASA Astrophysics Data System (ADS)
Eastman, R. M.; Wood, R.
2017-12-01
This study observes the 24-hour Lagrangian evolution of stratocumulus cloud amount and PBL depth in four eastern subtropical ocean basins: the NE Pacific, SE Pacific, SE Atlantic, and E Indian. Nearly 170,000 trajectories are computed using the 2-D wind field at 925mb and cloud properties are sampled along these trajectories twice daily as the A-Train satellite constellation passes overhead. Concurrent measurements of the overlying humidity and temperature profiles are interpolated from the ERA-Interim reanalysis grids. Cloud properties are sampled by MODIS and a measure of planetary boundary layer (PBL) depth is calculated using MODIS cloud top temperatures, CALIPSO lidar observations of cloud top heights, and ERA-Interim sea surface temperatures. High humidity overlying the PBL can reduce cloud top cooling by counteracting radiative cooling and by reducing evaporation within the entrainment zone. Both of these effects can slow the entrainment rate and change cloud evolution. To discern which effect is more important the humidity profile is broken into two distinct components: the specific humidity directly above the inversion, which is entraining into the boundary layer, and the column of specific humidity above that layer, which is radiatively interacting with the PBL, but not directly entraining. These two measures of humidity are compared in the Lagrangian framework. Results suggest that humidity above the PBL has a stronger effect on the Lagrangian PBL deepening rate compared to lower tropospheric stability. A comparison of PBL deepening rates driven by the entraining humidity versus the radiating humidity shows that the radiative effects of overlying humidity are dominant with respect to entrainment. However, the entraining effects of humidity are more important in prolonging cloud lifetime.
Absorbed Dose and Dose Equivalent Calculations for Modeling Effective Dose
NASA Technical Reports Server (NTRS)
Welton, Andrew; Lee, Kerry
2010-01-01
While in orbit, Astronauts are exposed to a much higher dose of ionizing radiation than when on the ground. It is important to model how shielding designs on spacecraft reduce radiation effective dose pre-flight, and determine whether or not a danger to humans is presented. However, in order to calculate effective dose, dose equivalent calculations are needed. Dose equivalent takes into account an absorbed dose of radiation and the biological effectiveness of ionizing radiation. This is important in preventing long-term, stochastic radiation effects in humans spending time in space. Monte carlo simulations run with the particle transport code FLUKA, give absorbed and equivalent dose data for relevant shielding. The shielding geometry used in the dose calculations is a layered slab design, consisting of aluminum, polyethylene, and water. Water is used to simulate the soft tissues that compose the human body. The results obtained will provide information on how the shielding performs with many thicknesses of each material in the slab. This allows them to be directly applicable to modern spacecraft shielding geometries.
NASA Technical Reports Server (NTRS)
Georgiev, G. T.; Butler, J. J.; Kowalewski, M. G.; Ding, L.
2012-01-01
Assessment of the effect of Vacuum Ultra Violet (VUV) irradiation on the Bidirectional Reflectance Distribution Function (BRDF) of Spectralon is presented in this paper. The sample was a 99% white Spectralon calibration standard irradiated with VUV source positioned at 60o off the irradiation direction for a total of 20 hours. The BRDF before and after VUV irradiation was measured and compared at number of wavelengths in the UV, VIS and IR. Non-isotropic directional degradation of Spectralon diffuser under ionizing radiation was detected at different BRDF measurement geometries primarily at UV spectral range. The 8o directional/hemispherical reflectance of the same sample was also measured and compared from 200nm to 2500nm. Index Terms BRDF, Reflectance, Multiangular, Spectralon, Remote Sensing
CALIPSO-Inferred Aerosol Direct Radiative Effects: Bias Estimates Using Ground-Based Raman Lidars
NASA Technical Reports Server (NTRS)
Thorsen, Tyler; Fu, Qiang
2015-01-01
Observational constraints on the change in the radiative energy budget caused by the presence of aerosols, i.e. the aerosol direct radiative effect (DRE), have recently been made using observations from the Cloud- Aerosol Lidar and Infrared Pathfinder Satellite (CALIPSO). CALIPSO observations have the potential to provide improved global estimates of aerosol DRE compared to passive sensor-derived estimates due to CALIPSO's ability to perform vertically-resolved aerosol retrievals over all surface types and over cloud. In this study we estimate the uncertainties in CALIPSO-inferred aerosol DRE using multiple years of observations from the Atmospheric Radiation Measurement (ARM) program's Raman lidars (RL) at mid-latitude and tropical sites. Examined are assumptions about the ratio of extinction-to-backscatter (i.e. the lidar ratio) made by the CALIPSO retrievals, which are needed to retrieve the aerosol extinction profile. The lidar ratio is shown to introduce minimal error in the mean aerosol DRE at the top-of-atmosphere and surface. It is also shown that CALIPSO is unable to detect all radiatively-significant aerosol, resulting in an underestimate in the magnitude of the aerosol DRE by 30â€"50%. Therefore, global estimates of the aerosol DRE inferred from CALIPSO observations are likely too weak.
EEG Changes Due to Experimentally Induced 3G Mobile Phone Radiation
Roggeveen, Suzanne; van Os, Jim; Viechtbauer, Wolfgang; Lousberg, Richel
2015-01-01
The aim of this study was to investigate whether a 15-minute placement of a 3G dialing mobile phone causes direct changes in EEG activity compared to the placement of a sham phone. Furthermore, it was investigated whether placement of the mobile phone on the ear or the heart would result in different outcomes. Thirty-one healthy females participated. All subjects were measured twice: on one of the two days the mobile phone was attached to the ear, the other day to the chest. In this single-blind, cross-over design, assessments in the sham phone condition were conducted directly preceding and following the mobile phone exposure. During each assessment, EEG activity and radiofrequency radiation were recorded jointly. Delta, theta, alpha, slowbeta, fastbeta, and gamma activity was computed. The association between radiation exposure and the EEG was tested using multilevel random regression analyses with radiation as predictor of main interest. Significant radiation effects were found for the alpha, slowbeta, fastbeta, and gamma bands. When analyzed separately, ear location of the phone was associated with significant results, while chest placement was not. The results support the notion that EEG alterations are associated with mobile phone usage and that the effect is dependent on site of placement. Further studies are required to demonstrate the physiological relevance of these findings. PMID:26053854
Brianna Caddle, Lura; Grant, Jeremy L; Szatkiewicz, Jin; van Hase, Johann; Shirley, Bobbi-Jo; Bewersdorf, Joerg; Cremer, Christoph; Arneodo, Alain; Khalil, Andre; Mills, Kevin D
2007-01-01
Radiation exposure is an occupational hazard for military personnel, some health care professionals, airport security screeners, and medical patients, with some individuals at risk for acute, high-dose exposures. Therefore, the biological effects of radiation, especially the potential for chromosome damage, are major occupational and health concerns. However, the biophysical mechanisms of chromosome instability subsequent to radiation-induced DNA damage are poorly understood. It is clear that interphase chromosomes occupy discrete structural and functional subnuclear domains, termed chromosome territories (CT), which may be organized into 'neighborhoods' comprising groups of specific CTs. We directly evaluated the relationship between chromosome positioning, neighborhood composition, and translocation partner choice in primary lymphocytes, using a cell-based system in which we could induce multiple, concentrated DNA breaks via high-dose irradiation. We critically evaluated mis-rejoining profiles and tested whether breaks occurring nearby were more likely to fuse than breaks occurring at a distance. We show that CT neighborhoods comprise heterologous chromosomes, within which inter-CT distances directly relate to translocation partner choice. These findings demonstrate that interphase chromosome arrangement is a principal factor in genomic instability outcomes in primary lymphocytes, providing a structural context for understanding the biological effects of radiation exposure, and the molecular etiology of tumor-specific translocation patterns.
EEG Changes Due to Experimentally Induced 3G Mobile Phone Radiation.
Roggeveen, Suzanne; van Os, Jim; Viechtbauer, Wolfgang; Lousberg, Richel
2015-01-01
The aim of this study was to investigate whether a 15-minute placement of a 3G dialing mobile phone causes direct changes in EEG activity compared to the placement of a sham phone. Furthermore, it was investigated whether placement of the mobile phone on the ear or the heart would result in different outcomes. Thirty-one healthy females participated. All subjects were measured twice: on one of the two days the mobile phone was attached to the ear, the other day to the chest. In this single-blind, cross-over design, assessments in the sham phone condition were conducted directly preceding and following the mobile phone exposure. During each assessment, EEG activity and radiofrequency radiation were recorded jointly. Delta, theta, alpha, slowbeta, fastbeta, and gamma activity was computed. The association between radiation exposure and the EEG was tested using multilevel random regression analyses with radiation as predictor of main interest. Significant radiation effects were found for the alpha, slowbeta, fastbeta, and gamma bands. When analyzed separately, ear location of the phone was associated with significant results, while chest placement was not. The results support the notion that EEG alterations are associated with mobile phone usage and that the effect is dependent on site of placement. Further studies are required to demonstrate the physiological relevance of these findings.
NASA Astrophysics Data System (ADS)
Irwansyah, Kuse, Naoyuki; Usagawa, Tsuyoshi
2017-08-01
Directivity pattern of an ordinary loudspeaker becomes more directive at higher frequencies. However, because a single loudspeaker tends to radiate uniformly in all directions at low frequencies, reverberation from surrounding building walls may affect speech intelligibility when installing a multiple-loudspeaker system at crossroads. As an alternative, a sharply directive sound source is recommended to be used, but in many cases the directivity of an ordinary loudspeaker is less sharp at lower frequencies. Therefore, in order to overcome such a limitation, this paper discusses the possibility of using four loudspeakers under active control to realize a quadrupole radiation pattern in low frequency range. In this study, the radiation pattern of a primary loudspeaker and three secondary loudspeakers has been modelled. By placing the loudspeakers close together in the direction of 0°, 90°, 180°, and 270°, it was theoretically demonstrated that a quadrupole radiation pattern can be shaped in the target frequency range up to 600 Hz by simply controlling the directivity in three of four directions which are 45°, 135°, 225°, and 315°. Although, the radiation pattern model is far from realistic configurations and conditions, it is possible to realize a quadrupole radiation pattern in the low frequency range.
Code of Federal Regulations, 2014 CFR
2014-01-01
... radiation from an ISFSI or MRS. 72.104 Section 72.104 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED... materials in effluents and direct radiation from an ISFSI or MRS. (a) During normal operations and... radioactive materials, radon and its decay products excepted, to the general environment, (2) Direct radiation...
Code of Federal Regulations, 2012 CFR
2012-01-01
... radiation from an ISFSI or MRS. 72.104 Section 72.104 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED... materials in effluents and direct radiation from an ISFSI or MRS. (a) During normal operations and... radioactive materials, radon and its decay products excepted, to the general environment, (2) Direct radiation...
Code of Federal Regulations, 2013 CFR
2013-01-01
... radiation from an ISFSI or MRS. 72.104 Section 72.104 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED... materials in effluents and direct radiation from an ISFSI or MRS. (a) During normal operations and... radioactive materials, radon and its decay products excepted, to the general environment, (2) Direct radiation...
Wang, Ren; Wang, Bing-Zhong; Huang, Wei-Ying; Ding, Xiao
2016-04-16
A compact reconfigurable antenna with an omnidirectional mode and four directional modes is proposed. The antenna has a main radiator and four parasitic elements printed on a dielectric substrate. By changing the status of diodes soldered on the parasitic elements, the proposed antenna can generate four directional radiation patterns and one omnidirectional radiation pattern. The main beam directions of the four directional modes are almost orthogonal and the four directional beams can jointly cover a 360° range in the horizontal plane, i.e., the main radiation plane of omnidirectional mode. The whole volume of the antenna and the control network is approximately 0.70 λ × 0.53 λ × 0.02 λ, where λ is the wavelength corresponding to the center frequency. The proposed antenna has a simple structure and small dimensions under the requirement that the directional radiation patterns can jointly cover the main radiation plane of the omnidirectional mode, therefore, it can be used in smart wireless sensor systems for different application scenarios.
Radiant energy required for infrared neural stimulation
Tan, Xiaodong; Rajguru, Suhrud; Young, Hunter; ...
2015-08-25
Infrared neural stimulation (INS) has been proposed as an alternative method to electrical stimulation because of its spatial selective stimulation. Independent of the mechanism for INS, to translate the method into a device it is important to determine the energy for stimulation required at the target structure. Custom-designed, flat and angle polished fibers, were used to deliver the photons. By rotating the angle polished fibers, the orientation of the radiation beam in the cochlea could be changed. INS-evoked compound action potentials and single unit responses in the central nucleus of the inferior colliculus (ICC) were recorded. X-ray computed tomography wasmore » used to determine the orientation of the optical fiber. Maximum responses were observed when the radiation beam was directed towards the spiral ganglion neurons (SGNs), whereas little responses were seen when the beam was directed towards the basilar membrane. The radiant exposure required at the SGNs to evoke compound action potentials (CAPs) or ICC responses was on average 18.9 ± 12.2 or 10.3 ± 4.9 mJ/cm 2, respectively. For cochlear INS it has been debated whether the radiation directly stimulates the SGNs or evokes a photoacoustic effect. The results support the view that a direct interaction between neurons and radiation dominates the response to INS.« less
Radiant energy required for infrared neural stimulation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tan, Xiaodong; Rajguru, Suhrud; Young, Hunter
Infrared neural stimulation (INS) has been proposed as an alternative method to electrical stimulation because of its spatial selective stimulation. Independent of the mechanism for INS, to translate the method into a device it is important to determine the energy for stimulation required at the target structure. Custom-designed, flat and angle polished fibers, were used to deliver the photons. By rotating the angle polished fibers, the orientation of the radiation beam in the cochlea could be changed. INS-evoked compound action potentials and single unit responses in the central nucleus of the inferior colliculus (ICC) were recorded. X-ray computed tomography wasmore » used to determine the orientation of the optical fiber. Maximum responses were observed when the radiation beam was directed towards the spiral ganglion neurons (SGNs), whereas little responses were seen when the beam was directed towards the basilar membrane. The radiant exposure required at the SGNs to evoke compound action potentials (CAPs) or ICC responses was on average 18.9 ± 12.2 or 10.3 ± 4.9 mJ/cm 2, respectively. For cochlear INS it has been debated whether the radiation directly stimulates the SGNs or evokes a photoacoustic effect. The results support the view that a direct interaction between neurons and radiation dominates the response to INS.« less
NASA Astrophysics Data System (ADS)
Smith, C. J.; Forster, P.; Richardson, T.; Myhre, G.
2016-12-01
Effective radiative forcing (ERF), rather than "traditional" radiative forcing (RF), has become an increasingly popular metric in recent years, as it more closely links the difference in the earth's top-of-atmosphere (TOA) energy budget to equilibrium near-surface temperature rise. One method to diagnose ERF is to take the difference of TOA radiative fluxes from two climate model runs (a perturbation and a control) with prescribed sea-surface temperatures and sea-ice coverage. ERF can be thought of as the sum of a direct forcing, which is the pure radiative effect of a forcing agent, plus rapid adjustments, which are changes in climate state triggered by the forcing agent that themselves affect the TOA energy budget and are unrelated to surface temperature changes.In addition to the classic experiment of doubling of CO2 (2xCO2), we analyse rapid adjustments to a tripling of methane (3xCH4), a quintupling of sulphate aerosol (5xSul), a ten times increase in black carbon (10xBC) and a 2% increase in the solar constant (2%Sol). We use CMIP-style climate model diagnostics from six participating models of the Precipitation Driver Response Model Intercomparison Project (PDRMIP).Assuming approximately linear contributions to the TOA flux differences, the rapid adjustments from changes in atmospheric temperature, surface temperature, surface albedo and water vapour can be cleanly and simply separated from the direct forcing by radiative kernels. The rapid adjustments are in turn decomposed into stratospheric and tropospheric components. We introduce kernels based on the HadGEM2 climate model and find similar results to those based on other models. Cloud adjustments are evaluated as a residual of the TOA radiative fluxes between all-sky and clear-sky runs once direct forcing and rapid adjustments have been subtracted. The cloud adjustments are also calculated online within the HadGEM2 model using the ISCCP simulator. For aerosol forcing experiments, rapid adjustments vary substantially between models. Much of the contribution to this model spread is in the cloud adjustments. We also notice a spread in the model calculations of direct forcing for greenhouse gases, which suggest differences in the radiative transfer parameterisations used by each model.
Analogue Hawking radiation in a dc-SQUID array transmission line.
Nation, P D; Blencowe, M P; Rimberg, A J; Buks, E
2009-08-21
We propose the use of a superconducting transmission line formed from an array of direct-current superconducting quantum interference devices for investigating analogue Hawking radiation. Biasing the array with a space-time varying flux modifies the propagation velocity of the transmission line, leading to an effective metric with a horizon. Being a fundamentally quantum mechanical device, this setup allows for investigations of quantum effects such as backreaction and analogue space-time fluctuations on the Hawking process.
NASA Technical Reports Server (NTRS)
Nelson, Gregory A.; Marshall, Tamara M.; Schubert, Wayne W.
1989-01-01
The effects of ionizing and nonionizing radiation effects on cell reproduction, differentiation, and mutation in vivo are studied using the nematode C. elegans. The relationships between fluence/dose and response and quality factor and linear energy transfer are analyzed. The data reveal that there is a complex repair pathway in the nematode and that mutants can be used to direct the sensitivity of the system to specific mutagens/radiation types.
The Effect of Topography on the Exposure of Airless Bodies to Space Radiation: Phobos Case Study
NASA Astrophysics Data System (ADS)
Stubbs, T. J.; Wang, Y.; Guo, J.; Schwadron, N.; Cooper, J. F.; Wimmer-Schweingruber, R. F.; Spence, H. E.; Jordan, A.; Sturner, S. J.; Glenar, D. A.; Wilson, J. K.
2017-12-01
The surfaces of airless bodies, such as the Moon and Phobos (innermost Martian moon), are directly exposed to the surrounding space environment, including energetic particle radiation from both the ever-present flux of galactic cosmic rays (GCRs) and episodic bursts of solar energetic particles (SEPs). Characterizing this radiation exposure is critical to our understanding of the evolution of these bodies from space weathering processes, such as radiation damage of regolith, radiolysis of organics and volatiles, and dielectric breakdown. Similarly, this also has important implications for the long-term radiation exposure of future astronauts and equipment on the surface. In this study, the focus is the influence of Phobian topography on the direct exposure of Phobos to space radiation. For a given point on its surface, this exposure depends on: (i) the solid angle subtended by the sky, (ii) the solid angle of the sky blocked by Mars, and (iii) the energy and angular distributions of ambient energetic particle populations. The sky solid angle, determined using the elevation of the local horizon calculated from a digital elevation model (DEM), can be significantly reduced around topographic lows, such as crater floors, or increased near highs like crater rims. The DEM used in this study was produced using images from the Mars Express High Resolution Stereo Camera (HRSC), and has the highest available spatial resolution ( 100m). The proximity of Phobos to Mars means the Martian disk appears large in the Phobian sky, but this only effects the moon's near side due its tidally locked orbit. Only isotropic distributions of energetic particles are initially considered, which is typically a reasonable assumption for GCRs and sometimes for SEPs. Observations of the radiation environments on Mars by Curiosity's Radiation Assessment Detector (RAD), and the Cosmic Ray Telescope for the Effects of Radiation (CRaTER) onboard the Lunar Reconnaissance Orbiter (LRO) at the Moon, will be used to estimate the average, annual radiation dose at the orbit of Phobos. These three elements will be combined to produce a map of radiation exposure on the surface of Phobos, which will be used to assess the implications for space weathering and future human exploration.
Vibration analysis and sound field characteristics of a tubular ultrasonic radiator.
Liang, Zhaofeng; Zhou, Guangping; Zhang, Yihui; Li, Zhengzhong; Lin, Shuyu
2006-12-01
A sort of tubular ultrasonic radiator used in ultrasonic liquid processing is studied. The frequency equation of the tubular radiator is derived, and its radiated sound field in cylindrical reactor is calculated using finite element method and recorded by means of aluminum foil erosion. The results indicate that sound field of tubular ultrasonic radiator in cylindrical reactor appears standing waves along both its radial direction and axial direction, and amplitudes of standing waves decrease gradually along its radial direction, and the numbers of standing waves along its axial direction are equal to the axial wave numbers of tubular radiator. The experimental results are in good agreement with calculated results.
Effects of solar dimming and brightening on the terrestrial carbon sink
NASA Astrophysics Data System (ADS)
Mercado, L.; Bellouin, N.; Sitch, S.; Boucher, O.; Huntingford, C.; Wild, M.; Cox, P. M.
2009-04-01
Plant photosynthesis increases with solar radiation. Recent studies have shown that photosynthesis is more efficient under diffuse light conditions (Gu et al., 2003, Niyogi et al., 2004, Oliveira et al., 2007, Roderick et al., 2001). Changes in cloud cover and atmospheric aerosol loadings from either volcanic and anthropogenic sources, modify the total radiation reaching the surface and the fraction of this radiation which is diffuse, with uncertain overall effects on plant productivity and the global land carbon sink. A decrease in total solar radiation (Liepert, 2002, Stanhill and Cohen, 2001, Wild et al., 2005) has been observed at the Earth surface over the 1950-1990 period, called solar dimming. Such dimming gradually started to transform into brightening in some regions of the world since the late 1980s (Wild et al. 2005). The effect of these changes in total solar radiation and associated changes in diffuse radiation and diffuse fraction on the land biosphere has not yet been accounted for in global carbon cycle simulations because such models lack the mechanism that includes the diffuse irradiance effects on photosynthesis In this study we estimate the total impact of variations in clouds and atmospheric aerosols on the land carbon sink using a global land carbon cycle model modified to account for the effects of variations in both direct and diffuse radiation on canopy photosynthesis (Mercado et al., 2007) during the global dimming and brightening period. References Gu L.H., Baldocchi D.D., Wofsy S.C., Munger J.W., Michalsky J.J., Urbanski S.P. & Boden T.A. (2003) Response of a deciduous forest to the Mount Pinatubo eruption: Enhanced photosynthesis. Science, 299, 2035-2038. Liepert B.G. (2002) Observed reductions of surface solar radiation at sites in the United States and worldwide from 1961 to 1990. 29, 1421. Mercado L.M., Huntingford C., Gash J.H.C., Cox P.M. & Jogireddy V. (2007) Improving the representation of radiation interception and photosynthesis for climate model applications. Tellus Series B-Chemical and Physical Meteorology, 59, 553-565. Niyogi D., Chang H.I., Saxena V.K., Holt T., Alapaty K., Booker F., Chen F., Davis K.J., Holben B., Matsui T., Meyers T., Oechel W.C., Pielke R.A., Wells R., Wilson K. & Xue Y.K. (2004) Direct observations of the effects of aerosol loading on net ecosystem CO2 exchanges over different landscapes. Geophysical Research Letters, 31. Oliveira P.H.F., Artaxo P., Pires C., De Lucca S., Procopio A., Holben B., Schafer J., Cardoso L.F., Wofsy S.C. & Rocha H.R. (2007) The effects of biomass burning aerosols and clouds on the CO2 flux in Amazonia. Tellus Series B-Chemical and Physical Meteorology, 59, 338-349. Roderick M.L., Farquhar G.D., Berry S.L. & Noble I.R. (2001) On the direct effect of clouds and atmospheric particles on the productivity and structure of vegetation. Oecologia, 129, 21-30. Stanhill G. & Cohen S. (2001) Global dimming: a review of the evidence for a widespread and significant reduction in global radiation with discussion of its probable causes and possible agricultural consequences. 107, 255-278. Wild M., Gilgen H., Roesch A., Ohmura A., Long C.N., Dutton E.G., Forgan B., Kallis A., Russak V. & Tsvetkov A. (2005) From dimming to brightening: Decadal changes in solar radiation at Earth's surface. Science, 308, 847-850.
Effects of preferential concentration on direct radiation transmission in a turbulent duct flow
NASA Astrophysics Data System (ADS)
Villafane, Laura; Banko, Andrew; Kim, Ji Hoon; Elkins, Chris; Eaton, John
2017-11-01
Inertial particles in turbulent flows preferentially concentrate, giving rise to spatial and temporal fluctuations of particle number density that affect radiation transmission through the medium. Positive particle correlations enhance direct transmission when compared to the exponential attenuation predicted by the Beer's Law for randomly distributed particles. In the context of a particle based solar receiver, this work studies the effects of preferential concentration and optical depth on direct transmission through a particle laden turbulent duct flow. Time resolved measurements of transmission through the mixture were performed for various particle loadings and Reynolds numbers, thus varying particle correlation lengths, optical depth and concentration fluctuations. These measurements were made using a photodiode to record the transmission of a collimated laser beam along the wall bisector of the duct. A synchronized high-speed camera provided particle positions along most of the beam path. Average and fluctuating radiation transmission results are compared to predictions derived from the imaged number density fields and to simplified analytical models. Simplified models are able to capture the correct trends with varying loading and preferential concentration. This work is funded by the Department of Energy's National Nuclear Security Administration, Grant #DE-NA0002373-1.
NASA Astrophysics Data System (ADS)
Pani, Shantanu Kumar; Wang, Sheng-Hsiang; Lin, Neng-Huei; Lee, Chung-Te; Tsay, Si-Chee; Holben, Brent; Janjai, Serm; Hsiao, Ta-Chih; Chuang, Ming-Tung; Chantara, Somporn
2016-04-01
Biomass-burning (BB) aerosols are the significant contributor to the regional/global aerosol loading and radiation budgets. BB aerosols affect the radiation budget of the earth and atmosphere by scattering and absorbing directly the incoming solar and outgoing terrestrial radiation. These aerosols can exert either cooling or warming effect on climate, depending on the balance between scattering and absorption. BB activities in the form of wildland forest fires and agricultural crop burning are very pronounced in the Indochina peninsular regions in Southeast Asia mainly in spring (late February to April) season. The region of interest includes Doi Ang Khang (19.93° N, 99.05° E, 1536 msl) in northern Thailand, as part of the Seven South East Asian Studies (7-SEAS)/BASELInE (Biomass-burning Aerosols & Stratocumulus Environment: Lifecycles & Interactions Experiment) campaign in 2013. In this study, for the first time, the direct aerosol radiative effects of BB aerosols over near-source BB emissions, during the peak loading spring season, in northern Indochina were investigated by using ground-based physical, chemical, and optical properties of aerosols as well as the aerosol optical and radiative transfer models. Information on aerosol parameters in the field campaign was used in the OPAC (Optical Properties of Aerosols and Clouds) model to estimate various optical properties corresponding to aerosol compositions. Clear-sky shortwave direct aerosol radiative effects were further estimated with a raditive transfer model SBDART (Santa Barbara DISORT Atmospheric Radiative Transfer). The columnar aerosol optical depth (AOD500) was found to be ranged from 0.26 to 1.13 (with the mean value 0.71 ± 0.24). Fine-mode (fine mode fraction ≈0.98, angstrom exponent ≈1.8) and significantly absorbing aerosols (columnar single-scattering albedo ≈0.89, asymmetry-parameter ≈0.67 at 441 nm wavelength) dominated in this region. Water soluble and black carbon (BC) aerosols mainly dominate the both surface mass concentration and the columnar burden. The BC contributed only 6% to the aerosol mass loading, but its contribution to the total AOD and net atmospheric forcing were 12% and 75%, respectively. The mean radiative forcing was -6.8 to -8.7 W m-2 at the top-of-atmosphere and -28 to -33 W m-2 at surface. Furthermore BC aerosols contributed 45-49% to the surface radiative forcing along with the water soluble aerosols (49-52%), thus, significantly contributing to solar dimming
UV Radiation: a new first year physics/life sciences laboratory experiment
NASA Astrophysics Data System (ADS)
Petelina, S. V.; Siddaway, J. M.
2010-12-01
Unfortunately, Australia leads the world in the number of skin cancer cases per capita. Three major factors that contribute to this are: 1) the level of damaging ultraviolet (UV) radiation in Australia is higher than in many other countries. This is caused, among other factors, by the stratospheric ozone depletion and Antarctic ozone hole; 2) many people in Australia are of Irish-Scottish origin and their skin can not repair the damage caused by the UV radiation as effectively as the skin of people of other origins; 3) Australia is one of the world’s leaders in the outdoor activities where people tend to spend more time outside. As our experience has shown, most Australian University students, high school students, and even high school teachers were largely unaware of the UV damage details and effective safety measures. Therefore, a need for new ways to educate people became apparent. The general aim of this new 1st year laboratory experiment, developed and first offered at La Trobe University (Melbourne, Australia) in 2009, is to investigate how UV-B radiation levels change under various solar illumination conditions and how effective different types of protection are. After pre-lab readings on physical concepts and biological effects of UV radiation, and after solving all pre-lab problems, the students go outside and measure the actual change in UV-B and UV-A radiation levels under various conditions. Some of these conditions are: direct sun, shade from a building, shade under the roof, reflection from various surfaces, direct sun through cheap and expensive sunglasses and eyeglasses, direct sun through various types of cloth and hair. The equipment used is the UV-Probe manufactured by sglux SolGel Technologies GmbH. The students’ feedback on this new laboratory experiment was very positive. It was ranked top among all physics experiments offered as part of that subject (Physics for Life Sciences) in 2009 and top among all physics experiments presented for peer evaluation at the Advanced Science Education Learning Laboratory Workshop in April 2010 at the University of Adelaide, Australia. All three main components of the UV Radiation experiment - pre-lab exercises, taking measurements, and a group discussion led by a demonstrator, were assessed by the students and by the teaching academics as a very important and valuable contribution to learning.
Effects of heavy ions on inactivation and DNA double strand breaks in Deinococcus radiodurans R1.
Zimmermann, H; Schafer, M; Schmitz, C; Bucker, H
1994-10-01
Inactivation and double strand break (dsb) induction after heavy ion irradiation were studied in stationary phase cells of the highly radiation resistant bacterium Deinococcus radiodurans R1. There is evidence that the radiation sensitivity of this bacterium is nearly independent on energy in the range of up to 15 MeV/u for lighter ions (Ar). The responses to dsb induction for charged particles show direct relationship between increasing radiation dose and residual intact DNA.
Satellite remote sensing of primary production
NASA Technical Reports Server (NTRS)
Tucker, C. J.; Sellers, P. J.
1986-01-01
Leaf structure and function are shown to result in distinctive variations in the absorption and reflection of solar radiation from plant canopies. The leaf properties that determine the radiation-interception characteristics of plant canopies are directly linked to photosynthesis, stomatal resistance and evapotranspiration and can be inferred from measurements of reflected solar energy. The effects of off-nadir viewing and atmospheric constituents, coupled with the need to measure changing surface conditions, emphasize the need for multitemporal measurements of reflected radiation if primary production is to be estimated.
NASA Astrophysics Data System (ADS)
Meloni, Daniela; di Sarra, Alcide; Brogniez, Gérard; Denjean, Cyrielle; De Silvestri, Lorenzo; Di Iorio, Tatiana; Formenti, Paola; Gómez-Amo, José L.; Gröbner, Julian; Kouremeti, Natalia; Liuzzi, Giuliano; Mallet, Marc; Pace, Giandomenico; Sferlazzo, Damiano M.
2018-03-01
Detailed measurements of radiation, atmospheric and aerosol properties were carried out in summer 2013 during the Aerosol Direct Radiative Impact on the regional climate in the MEDiterranean region (ADRIMED) campaign in the framework of the Chemistry-Aerosol Mediterranean Experiment (ChArMEx) experiment. This study focusses on the characterization of infrared (IR) optical properties and direct radiative effects of mineral dust, based on three vertical profiles of atmospheric and aerosol properties and IR broadband and narrowband radiation from airborne measurements, made in conjunction with radiosonde and ground-based observations at Lampedusa, in the central Mediterranean. Satellite IR spectra from the Infrared Atmospheric Sounder Interferometer (IASI) are also included in the analysis. The atmospheric and aerosol properties are used as input to a radiative transfer model, and various IR radiation parameters (upward and downward irradiance, nadir and zenith brightness temperature at different altitudes) are calculated and compared with observations. The model calculations are made for different sets of dust particle size distribution (PSD) and refractive index (RI), derived from observations and from the literature. The main results of the analysis are that the IR dust radiative forcing is non-negligible and strongly depends on PSD and RI. When calculations are made using the in situ measured size distribution, it is possible to identify the refractive index that produces the best match with observed IR irradiances and brightness temperatures (BTs). The most appropriate refractive indices correspond to those determined from independent measurements of mineral dust aerosols from the source regions (Tunisia, Algeria, Morocco) of dust transported over Lampedusa, suggesting that differences in the source properties should be taken into account. With the in situ size distribution and the most appropriate refractive index the estimated dust IR radiative forcing efficiency is +23.7 W m-2 at the surface, -7.9 W m-2 within the atmosphere, and +15.8 W m-2 at the top of the atmosphere. The use of column-integrated dust PSD from AERONET may also produce a good agreement with measured irradiances and BTs, but with significantly different values of the RI. This implies large differences, up to a factor of 2.5 at surface, in the estimated dust radiative forcing, and in the IR heating rate. This study shows that spectrally resolved measurements of BTs are important to better constrain the dust IR optical properties, and to obtain a reliable estimate of its radiative effects. Efforts should be directed at obtaining an improved description of the dust size distribution and its vertical distribution, as well as at including regionally resolved optical properties.
NASA Astrophysics Data System (ADS)
Bangalath, Hamza Kunhu; Stenchikov, Georgiy
2015-05-01
To investigate the influence of direct radiative effect of dust on the tropical summer rain belt across the Middle East and North Africa (MENA), the present study utilizes the high-resolution capability of an Atmospheric General Circulation Model, the High-Resolution Atmospheric Model. Ensembles of Atmospheric Model Intercomparison Project style simulations have been conducted with and without dust radiative impacts, to differentiate the influence of dust on the tropical rain belt. The analysis focuses on summer season. The results highlight the role of dust-induced responses in global- and regional-scale circulations in determining the strength and the latitudinal extent of the tropical rain belt. A significant response in the strength and position of the local Hadley circulation is predicted in response to meridionally asymmetric distribution of dust and the corresponding radiative effects. Significant responses are also found in regional circulation features such as African Easterly Jet and West African Monsoon circulation. Consistent with these dynamic responses at various scales, the tropical rain belt across MENA strengthens and shifts northward. Importantly, the summer precipitation over the semiarid strip south of Sahara, including Sahel, increases up to 20%. As this region is characterized by the "Sahel drought," the predicted precipitation sensitivity to the dust loading over this region has a wide range of socioeconomic implications. Overall, the study demonstrates the extreme importance of incorporating dust radiative effects and the corresponding circulation responses at various scales, in the simulations and future projections of this region's climate.
Pituitary-directed medical therapy in Cushing's disease.
Petersenn, Stephan; Fleseriu, Maria
2015-04-01
Transsphenoidal surgery remains the first line therapy in Cushing's disease, but a large number of patients will not be cured or disease will recur over time. Repeat pituitary surgery, bilateral adrenalectomy, and radiation have limitations with respect to efficacy and/or side effects. Therefore, there is a clear need for an effective medical treatment. The studies reviewed here suggest a role for pituitary-directed therapies, applying multireceptor ligand somatostatin analogs like pasireotide or second-generation dopamine agonists. Retinoic acid has been also studied in a small prospective study. These compounds target ACTH-secretion at the pituitary level and possibly inhibit corticotrope proliferation. Specific side effects of these compounds need to be considered, especially when used as long-term therapy. These novel approaches could provide options for treatment of patients in whom surgery has failed or is not possible, and while awaiting effects of radiation therapy. Preoperative use to decrease cortisol excess, potentially reducing perioperative complications, needs to be further studied.
HZE Radiation Non-Targeted Effects on the Microenvironment That Mediate Mammary Carcinogenesis.
Barcellos-Hoff, Mary Helen; Mao, Jian-Hua
2016-01-01
Clear mechanistic understanding of the biological processes elicited by radiation that increase cancer risk can be used to inform prediction of health consequences of medical uses, such as radiotherapy, or occupational exposures, such as those of astronauts during deep space travel. Here, we review the current concepts of carcinogenesis as a multicellular process during which transformed cells escape normal tissue controls, including the immune system, and establish a tumor microenvironment. We discuss the contribution of two broad classes of radiation effects that may increase cancer: radiation targeted effects that occur as a result of direct energy deposition, e.g., DNA damage, and non-targeted effects (NTE) that result from changes in cell signaling, e.g., genomic instability. It is unknown whether the potentially greater carcinogenic effect of high Z and energy (HZE) particle radiation is a function of the relative contribution or extent of NTE or due to unique NTE. We addressed this problem using a radiation/genetic mammary chimera mouse model of breast cancer. Our experiments suggest that NTE promote more aggressive cancers, as evidenced by increased growth rate, transcriptomic signatures, and metastasis, and that HZE particle NTE are more effective than reference γ-radiation. Emerging evidence suggest that HZE irradiation dampens antitumor immunity. These studies raise concern that HZE radiation exposure not only increases the likelihood of developing cancer but also could promote progression to more aggressive cancer with a greater risk of mortality.
[Bio-objects and biological methods of space radiation effects evaluation].
Kaminskaia, E V; Nevzgodina, L V; Platova, N G
2009-01-01
The unique conditions of space experiments place austere requirements to bio-objects and biological methods of radiation effects evaluation. The paper discusses suitability of a number of bio-objects varying in stage of evolution and metabolism for space researches aimed to state common patterns of the radiation damage caused by heavy ions (HI), and character of HI-cell interaction. Physical detectors in space experiments of the BIOBLOCK series make it possible to identify bio-objects hit by space HI and to set correlation between HI track topography and biological effect. The paper provides an all-round description of the bio-objects chosen for two BIOBLOCK experiments (population of hydrophyte Wolffia arrhiza (fam. duckweed) and Lactuca sativa seeds) and the method of evaluating effects from single space radiation HI. Direct effects of heavy ions on cells can be determined by the criteria of chromosomal aberrations and delayed morphologic abnormalities. The evaluation results are compared with the data about human blood lymphocytes. Consideration is being given to the procedures of test-objects' treatment and investigation.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kaothekar, Sachin, E-mail: sackaothekar@gmail.com
I have studied the effects of finite electron inertia, finite ion Larmor radius (FLR) corrections, and radiative heat-loss function on the thermal instability of an infinite homogeneous, viscous plasma incorporating the effect of thermal conductivity for star formation in interstellar medium (ISM). A general dispersion relation is derived using the normal mode analysis method with the help of relevant linearized perturbation equations of the problem. The wave propagation is discussed for longitudinal and transverse directions to the external magnetic field and the conditions of modified thermal instabilities and stabilities are discussed in different cases. We find that the thermal instabilitymore » criterion is get modified into radiative instability criterion by inclusion of radiative heat-loss functions with thermal conductivity. The viscosity of medium removes the effect of FLR corrections from the condition of radiative instability. Numerical calculation shows stabilizing effect of heat-loss function, viscosity and FLR corrections, and destabilizing effect of finite electron inertia on the thermal instability. Results carried out in this paper shows that stars are formed in interstellar medium mainly due to thermal instability.« less
Ishikawa, Masayori; Nagase, Naomi; Matsuura, Taeko; Hiratsuka, Junichi; Suzuki, Ryusuke; Miyamoto, Naoki; Sutherland, Kenneth Lee; Fujita, Katsuhisa; Shirato, Hiroki
2015-03-01
The scintillator with optical fiber (SOF) dosimeter consists of a miniature scintillator mounted on the tip of an optical fiber. The scintillator of the current SOF dosimeter is a 1-mm diameter hemisphere. For a scintillation dosimeter coupled with an optical fiber, measurement accuracy is influenced by signals due to Cerenkov radiation in the optical fiber. We have implemented a spectral filtering technique for compensating for the Cerenkov radiation effect specifically for our plastic scintillator-based dosimeter, using a wavelength-separated counting method. A dichroic mirror was used for separating input light signals. Individual signal counting was performed for high- and low-wavelength light signals. To confirm the accuracy, measurements with various amounts of Cerenkov radiation were performed by changing the incident direction while keeping the Ir-192 source-to-dosimeter distance constant, resulting in a fluctuation of <5%. Optical fiber bending was also addressed; no bending effect was observed for our wavelength-separated SOF dosimeter. © The Author 2015. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.
Radiative Effects of the Diurnal Cycle of Clouds and their Response to Climate Change
NASA Astrophysics Data System (ADS)
Yin, J.; Porporato, A. M.
2017-12-01
Clouds effectively control the Earth's energy budget by reflecting solar radiation and restricting the terrestrial one. While these dynamics have been regarded as one of vexing problem in understanding the climate system and have thus attracted much attention in the literature, less research has been devoted to the diurnal cycle of clouds (DCC). Here we first quantify the mean, amplitude, and phase of the cloud cycles in current climate models and compare them with satellite observations and reanalysis data. We show that the mean values appear to be reliable but the amplitude and phase of the DCC are less consistent. These inconsistencies are interpreted using a minimalist radiative balance model to demonstrate their impacts on surface temperature. The DCC radiative impacts are then analyzed in terms of phase shift and amplitude modulation of DCC and their so-called cloud radiative effects are estimated directly from climate model outputs. This allows us to show that DCC variations may account for up to 10-20% of the total cloud radiative impacts, calling for increased attention to the temporal evolution of the DCC in climate models.
New Modeling Approaches to Investigate Cell Signaling in Radiation Response
NASA Technical Reports Server (NTRS)
Plante, Ianik; Cucinotta, Francis A.; Ponomarev, Artem L.
2011-01-01
Ionizing radiation damages individual cells and tissues leading to harmful biological effects. Among many radiation-induced lesions, DNA double-strand breaks (DSB) are considered the key precursors of most early and late effects [1] leading to direct mutation or aberrant signal transduction processes. In response to damage, a flow of information is communicated to cells not directly hit by the radiation through signal transduction pathways [2]. Non-targeted effects (NTE), which includes bystander effects and genomic instability in the progeny of irradiated cells and tissues, may be particularly important for space radiation risk assessment [1], because astronauts are exposed to a low fluence of heavy ions and only a small fraction of cells are traversed by an ion. NTE may also have important consequences clinical radiotherapy [3]. In the recent years, new simulation tools and modeling approaches have become available to study the tissue response to radiation. The simulation of signal transduction pathways require many elements such as detailed track structure calculations, a tissue or cell culture model, knowledge of biochemical pathways and Brownian Dynamics (BD) propagators of the signaling molecules in their micro-environment. Recently, the Monte-Carlo simulation code of radiation track structure RITRACKS was used for micro and nano-dosimetry calculations [4]. RITRACKS will be used to calculate the fraction of cells traversed by an ion and delta-rays and the energy deposited in cells in a tissue model. RITRACKS also simulates the formation of chemical species by the radiolysis of water [5], notably the .OH radical. This molecule is implicated in DNA damage and in the activation of the transforming growth factor beta (TGF), a signaling molecule involved in NTE. BD algorithms for a particle near a membrane comprising receptors were also developed and will be used to simulate trajectories of signaling molecules in the micro-environment and characterize autocrine and paracrine cell communication and signal transduction.
Directivity pattern of the sound radiated from axisymmetric stepped plates.
He, Xiping; Yan, Xiuli; Li, Na
2016-08-01
For the purpose of optimal design and efficient utilization of the kind of stepped plate radiator in air, in this contribution, an approach for calculation of the directivity pattern of the sound radiated from a stepped plate in flexural vibration with a free edge is developed based on Kirchhoff-Love hypothesis and Rayleigh integral principle. Experimental tests of directivity pattern for a fabricated flat plate and two fabricated plates with one and two step radiators were carried out. It shows that the configuration of the measured directivity patterns by the proposed analytic approach is similar to those of the calculated approach. Comparison of the agreement between the calculated directivity pattern of a stepped plate and its corresponding theoretical piston show that the former radiator is equivalent to the latter, and the diffraction field generated by the unbaffled upper surface may be small. It also shows that the directivity pattern of a stepped radiator is independent of the metallic material but dependent on the thickness of base plate and resonant frequency. The thicker the thickness of base plate, the more directive the radiation is. The proposed analytic approach in this work may be adopted for any other plates with multi-steps.
WRF-CMAQ simulations of Aerosol Direct Effects
CMAQ and WRF output filesThis dataset is associated with the following publication:Gan, C., J. Pleim , R. Mathur , C. Hogrefe , C.N. Long, J. Xing, D. Wong , R. Gilliam , and C. Wei. Assessment of long-term WRF–CMAQ simulations for understanding direct aerosol effects on radiation "brightening" in the United States. Atmospheric Chemistry and Physics. Copernicus Publications, Katlenburg-Lindau, GERMANY, 15: 12193-12209, (2015).
[The interauricular laser therapy of rheumatoid arthritis].
Sidorov, V D; Mamiliaeva, D R; Gontar', E V; Reformatskaia, S Iu
1999-01-01
Investigations have proved the ability of interauricular low-intensity infrared laser therapy (0.89 nm, 7.6 J/cm) to produce anti-inflammatory, immunomodulating action in patients with rheumatoid arthritis. The method has selective, pathogenetically directed immunomodulating effect the mechanism of which is similar to that of basic antirheumatic drugs and of intravenous laser radiation of blood. This laser therapy can be used as an alternative to intravenous blood radiation being superior as a noninvasive method. Interauricular laser therapy can potentiate the effects of nonsteroid anti-inflammatory drugs, cytostatics and diminish their side effects.
NASA Astrophysics Data System (ADS)
Koepferl, Christine M.; Robitaille, Thomas P.
2017-11-01
When modeling astronomical objects throughout the universe, it is important to correctly treat the limitations of the data, for instance finite resolution and sensitivity. In order to simulate these effects, and to make radiative transfer models directly comparable to real observations, we have developed an open-source Python package called the FluxCompensator that enables the post-processing of the output of 3D Monte Carlo radiative transfer codes, such as Hyperion. With the FluxCompensator, realistic synthetic observations can be generated by modeling the effects of convolution with arbitrary point-spread functions, transmission curves, finite pixel resolution, noise, and reddening. Pipelines can be applied to compute synthetic observations that simulate observatories, such as the Spitzer Space Telescope or the Herschel Space Observatory. Additionally, this tool can read in existing observations (e.g., FITS format) and use the same settings for the synthetic observations. In this paper, we describe the package as well as present examples of such synthetic observations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Koepferl, Christine M.; Robitaille, Thomas P., E-mail: koepferl@usm.lmu.de
When modeling astronomical objects throughout the universe, it is important to correctly treat the limitations of the data, for instance finite resolution and sensitivity. In order to simulate these effects, and to make radiative transfer models directly comparable to real observations, we have developed an open-source Python package called the FluxCompensator that enables the post-processing of the output of 3D Monte Carlo radiative transfer codes, such as Hyperion. With the FluxCompensator, realistic synthetic observations can be generated by modeling the effects of convolution with arbitrary point-spread functions, transmission curves, finite pixel resolution, noise, and reddening. Pipelines can be applied tomore » compute synthetic observations that simulate observatories, such as the Spitzer Space Telescope or the Herschel Space Observatory . Additionally, this tool can read in existing observations (e.g., FITS format) and use the same settings for the synthetic observations. In this paper, we describe the package as well as present examples of such synthetic observations.« less
Consistency between satellite-derived and modeled estimates of the direct aerosol effect.
Myhre, Gunnar
2009-07-10
In the Intergovernmental Panel on Climate Change Fourth Assessment Report, the direct aerosol effect is reported to have a radiative forcing estimate of -0.5 Watt per square meter (W m(-2)), offsetting the warming from CO2 by almost one-third. The uncertainty, however, ranges from -0.9 to -0.1 W m(-2), which is largely due to differences between estimates from global aerosol models and observation-based estimates, with the latter tending to have stronger (more negative) radiative forcing. This study demonstrates consistency between a global aerosol model and adjustment to an observation-based method, producing a global and annual mean radiative forcing that is weaker than -0.5 W m(-2), with a best estimate of -0.3 W m(-2). The physical explanation for the earlier discrepancy is that the relative increase in anthropogenic black carbon (absorbing aerosols) is much larger than the overall increase in the anthropogenic abundance of aerosols.
Inertial mass of an elementary particle from the holographic scenario
NASA Astrophysics Data System (ADS)
Giné, Jaume
2017-03-01
Various attempts have been made to fully explain the mechanism by which a body has inertial mass. Recently, it has been proposed that this mechanism is as follows: when an object accelerates in one direction, a dynamical Rindler event horizon forms in the opposite direction, suppressing Unruh radiation on that side by a Rindler-scale Casimir effect whereas the radiation on the other side is only slightly reduced by a Hubble-scale Casimir effect. This produces a net Unruh radiation pressure force that always opposes the acceleration, just like inertia, although the masses predicted are twice those expected, see Ref. 17. In a later work, an error was corrected so that its prediction improves to within 26% of the Planck mass, see Ref. 10. In this paper, the expression of the inertial mass of a elementary particle is derived from the holographic scenario giving the exact value of the mass of a Planck particle when it is applied to a Planck particle.
Systems level test and simulation for photonic processing systems
NASA Astrophysics Data System (ADS)
Erteza, I. A.; Stalker, K. T.
1995-08-01
Photonic technology is growing in importance throughout DOD. Programs have been underway in each of the Services to demonstrate the ability of photonics to enhance current electronic performance in several prototype systems, such as the Navy's SLQ-32 radar warning receiver, the Army's multi-role survivable radar and the phased array radar controller for the Airborne Warning and Control System (AWACS) upgrade. Little, though, is known about radiation effects; the component studies do not furnish the information needed to predict overall system performance in a radiation environment. To date, no comprehensive test and analysis program has been conducted to evaluate sensitivity of overall system performance to the radiation environment. The goal of this program is to relate component level effects to system level performance through modeling and testing of a selected optical processing system, and to help direct component testing to items which can directly and adversely affect overall system performance. This report gives a broad overview of the project, highlighting key results.
Radiation biophysical aspects of charged particles: From the nanoscale to therapy
NASA Astrophysics Data System (ADS)
Scifoni, Emanuele
2015-06-01
Charged particle applications for radiotherapy are motivated by their specific advantages in terms of dose delivery and biological effect. These advantages have to a large extent originated from the peculiarities of ion beam energy deposition patterns in the medium on a microscopic, down to a nanoscopic scale. A large amount of research was conducted in this direction, especially in the last two decades, profiting also from the parallel investigations going on in radiation protection for space exploration. The main biophysical aspects of charged particles, which are relevant to hadrontherapy are shortly reviewed in the present contribution, namely focusing on relative biological effectiveness (RBE), oxygen enhancement ratio (OER) and combination with radiosensitizers. A summary of present major research direction on both microscopic and macroscopic assessment of the specific mechanism of radiation damage will be given, as well as several open challenges for a better understanding of the whole process, which still limit the full exploitation of ion beams for radiotherapy.
Impacts of Saharan Dust on the Atmospheric Radiative Balance in the Caribbean during SALTRACE 2013
NASA Astrophysics Data System (ADS)
Sauer, D. N.; Weinzierl, B.; Gross, S.; Minikin, A.; Freudenthaler, V.; Gasteiger, J.; Mayer, B. C.
2013-12-01
Direct and indirect aerosol radiative effects represent one of the largest uncertainties in the modeling of the climate system. To better quantify the effects of aerosols on the Earth's radiative balance and understand important physical effects on small scales such as the influence of aerosols on clouds, detailed measurements of aerosol properties are needed to build a globally representative data set. Mineral dust is among the most abundant aerosols and the Sahara Desert constitutes its largest source. During frequent dust outbreaks thick elevated aerosol layers are formed and transported over large distances -often across the Atlantic Ocean into the Caribbean. The Saharan Aerosol Long-range Transport and Aerosol-Cloud-Interaction Experiment (SALTRACE) in June/July 2013 continues the SAMUM field experiments conducted in 2006 and 2008. It aims to study the long-range transport of Saharan mineral dust, the properties of aged mineral dust aerosol, and its impact on radiative quantities and cloud processes. The experiment led to an extensive data set on dust layers from Senegal to the Caribbean using airborne in-situ and remote sensing measurements, complemented with ground-based remote sensing and in-situ measurements on sites in Barbados and Puerto Rico as well as satellite remote sensing data. The airborne data were obtained with an extensive aerosol payload aboard the DLR-operated Falcon 20E research aircraft. The measurements cover the entire size range of atmospheric aerosol with a combination of cabin-operated and wing-mounted instruments. In addition, particle properties such as absorption coefficients and volatility are measured. A nadir-looking 2-μm Doppler-lidar system aboard the aircraft was used for wind measurements and served as a path finder for the selection of representative aerosol in-situ levels. In the Caribbean the dust usually arrives in several layers with distinct properties: the mostly undisturbed pure dust layer in altitudes up to 4-5 km, a transition layer where mixing and cloud processing has occurred, and a lower layer with a significant contribution from marine boundary layer aerosol. Here we present a case study of the direct radiative effects of Saharan dust layers found over Barbados using airborne in-situ and ground-based lidar observations. Using the radiative transfer package libRadtran we estimate the direct radiative forcing and radiative heating rate profiles inside the tropospheric column over Barbados. To deduce aerosol optical properties for the radiative transfer model, particle size distributions, aerosol refractive indices, and shape distributions are obtained from in-situ data. Coinciding lidar observations are used to deduce the vertical extent and structure of the different aerosol layers. To study the effect of aerosol aging on the radiative balance we compare the model results from in-situ data obtained in Barbados with results based on data from Senegal and the Cape Verde region and from the SAMUM field experiments, which characterized the dust properties near the source.
NASA Technical Reports Server (NTRS)
Lee, J. H.; Shiu, Y. J.; Weaver, W. R.
1980-01-01
The feasibility of direct solar pumping of an iodine photodissociation laser at lambda = 1.315 microns was investigated. Threshold inversion density and effect of elevated temperature (up to 670 K) on the laser output were measured. These results and the concentration of solar radiation required for the solar pumped iodine laser are discussed.
Thermal ablation therapeutics based on CNx multi-walled nanotubes
Torti, Suzy V; Byrne, Fiona; Whelan, Orla; Levi, Nicole; Ucer, Burak; Schmid, Michael; Torti, Frank M; Akman, Steven; Liu, Jiwen; Ajayan, Pulickel M; Nalamasu, Omkaram; Carroll, David L
2007-01-01
We demonstrate that nitrogen doped, multi-walled carbon nanotubes (CNx-MWNT) result in photo-ablative destruction of kidney cancer cells when excited by near infrared (NIR) irradiation. Further, we show that effective heat transduction and cellular cytotoxicity depends on nanotube length: effective NIR coupling occurs at nanotube lengths that exceed half the wavelength of the stimulating radiation, as predicted in classical antenna theory. We also demonstrate that this radiation heats the nanotubes through induction processes, resulting in significant heat transfer to surrounding media and cell killing at extraordinarily small radiation doses. This cell death was attributed directly to photothermal effect generated within the culture, since neither the infrared irradiation itself nor the CNx-MWNT were toxic to the cells. PMID:18203437
Radiation shielding properties of barite coated fabric by computer programme
DOE Office of Scientific and Technical Information (OSTI.GOV)
Akarslan, F.; Molla, T.; Üncü, I. S.
2015-03-30
With the development of technology radiation started to be used in variety of different fields. As the radiation is hazardous for human health, it is important to keep radiation dose as low as possible. This is done mainly using shielding materials. Barite is one of the important materials in this purpose. As the barite is not used directly it can be used in some other materials such as fabric. For this purposes barite has been coated on fabric in order to improve radiation shielding properties of fabric. Determination of radiation shielding properties of coated fabric has been done by usingmore » computer program written C# language. With this program the images obtained from digital Rontgen films is used to determine radiation shielding properties in terms of image processing numerical values. Those values define radiation shielding and in this way the coated barite effect on radiation shielding properties of fabric has been obtained.« less
A method to reduce patient's eye lens dose in neuro-interventional radiology procedures
NASA Astrophysics Data System (ADS)
Safari, M. J.; Wong, J. H. D.; Kadir, K. A. A.; Sani, F. M.; Ng, K. H.
2016-08-01
Complex and prolonged neuro-interventional radiology procedures using the biplane angiography system increase the patient's risk of radiation-induced cataract. Physical collimation is the most effective way of reducing the radiation dose to the patient's eye lens, but in instances where collimation is not possible, an attenuator may be useful in protecting the eyes. In this study, an eye lens protector was designed and fabricated to reduce the radiation dose to the patients' eye lens during neuro-interventional procedures. The eye protector was characterised before being tested on its effectiveness in a simulated aneurysm procedure on an anthropomorphic phantom. Effects on the automatic dose rate control (ADRC) and image quality are also evaluated. The eye protector reduced the radiation dose by up to 62.1% at the eye lens. The eye protector is faintly visible in the fluoroscopy images and increased the tube current by a maximum of 3.7%. It is completely invisible in the acquisition mode and does not interfere with the clinical procedure. The eye protector placed within the radiation field of view was able to reduce the radiation dose to the eye lens by direct radiation beam of the lateral x-ray tube with minimal effect on the ADRC system.
Radiation Exposure and Health Effects – is it Time to Reassess the Real Consequences?
Thomas, G.A.; Symonds, P.
2017-01-01
Our acceptance of exposure to radiation is somewhat schizophrenic. We accept that the use of high doses of radiation is still one of the most valuable weapons in our fight against cancer, and believe that bathing in radioactive spas is beneficial. On the other hand, as a species, we are fearful of exposure to man-made radiation as a result of accidents related to power generation, even though we understand that the doses are orders of magnitude lower than those we use everyday in medicine. The 70th anniversary of the detonation of the atomic bombs in Hiroshima and Nagasaki was marked in 2015. The 30th anniversary of the Chernobyl nuclear power plant accident will be marked in April 2016. March 2016 also sees the fifth anniversary of the accident at the Fukushima nuclear power plant. Perhaps now is an opportune time to assess whether we are right to be fearful of the effects of low doses of radiation, or whether actions taken because of our fear of radiation actually cause a greater detriment to health than the direct effect of radiation exposure. PMID:26880062
Radiation Effects on Current Field Programmable Technologies
NASA Technical Reports Server (NTRS)
Katz, R.; LaBel, K.; Wang, J. J.; Cronquist, B.; Koga, R.; Penzin, S.; Swift, G.
1997-01-01
Manufacturers of field programmable gate arrays (FPGAS) take different technological and architectural approaches that directly affect radiation performance. Similar y technological and architectural features are used in related technologies such as programmable substrates and quick-turn application specific integrated circuits (ASICs). After analyzing current technologies and architectures and their radiation-effects implications, this paper includes extensive test data quantifying various devices total dose and single event susceptibilities, including performance degradation effects and temporary or permanent re-configuration faults. Test results will concentrate on recent technologies being used in space flight electronic systems and those being developed for use in the near term. This paper will provide the first extensive study of various configuration memories used in programmable devices. Radiation performance limits and their impacts will be discussed for each design. In addition, the interplay between device scaling, process, bias voltage, design, and architecture will be explored. Lastly, areas of ongoing research will be discussed.
NASA Astrophysics Data System (ADS)
Du, Minglong; Yang, Lijun
2017-10-01
A linear analysis method was used to investigate the mechanics of radiation heat loss and mass transfer in the porous wall of premixed annular flames and their effect on thermodiffusive instability. The dispersion relation between the disturbance wave growth rate and wavenumber was calculated numerically. Results showed that radiation heat loss elevated the annular flame slightly away from the porous wall. In the annular flame with small Lewis numbers, radiation heat loss changed the thermodiffusive instability from a pulsating to a cellular state, while for the large Lewis numbers, only the pulsating instability was represented. Increasing radiation heat loss and the radius of the porous wall enhanced the instability of the annular flames. Heat losses decreased with the continued increase in thickness of the porous wall and the decrease in porosity. Annular flames with long-wave mode along the angular direction were more unstable than the shortwave mode.
NASA Astrophysics Data System (ADS)
Oikarinen, L.
Solar UV and visible radiation scattered at the limb of the Earth's atmosphere is used for measuring density profiles of atmosperic trace gases. For example, the OSIRIS instrument on Odin and SCIAMACHY on Envisat use this technique. A limb-viewing instrument does not see Earth's surface or tropospheric clouds directly. However, in- direct light reflected from the surface or low altitude clouds can make up tens of per cents of the signal. Furthermore, the surface area that contributes to limb intensity ex- tends over 1000 km along the instrument line-of-sight and 200 km across it. Over this area surface reflectivity can vary from almost 0% to 100%. Inaccurate modelling of reflected intensity is a potential source of error in the trace gas retrieval. Generally, radiative transfer models used for analysing limb measure- ments have to assume that the surface has a constant albedo. We have used a three- dimensional Monte Carlo radiative transfer model to study the effects of surface vari- ation to limb radiance. Based on the simulations, we have developed an approximate method for averaging surface albedo for limb scattering measurements with the help of a simple single scattering radiative transfer model.
NASA Technical Reports Server (NTRS)
Ville, J. M.; Silcox, R. J.
1980-01-01
The radiation of sound from an inlet as a function of flow velocity, frequency, duct mode structure, and inlet geometry was examined by using a spinning mode synthesizer to insure a given space-time structure inside the duct. Measurements of the radiation pattern (amplitude and phase) and of the pressure reflection coefficient were obtained over an azimuthal wave number range of 0 to 6 and a frequency range up to 5000 Hz for an unflanged duct and a bellmouth. The measured radiated field and pressure reflection coefficient without flow for the unflanged duct agree reasonably well with theory. The influence of the inlet contour appears to be very drastic near the cut-on frequency of a mode and reasonable agreement is found between the bellmouth pressure reflection coefficient and a infinite hyperboloidal inlet theory. It is also shown that the flow has a weak effect on the amplitude of the directivity factor but significantly shifts the directivity factor phase. The influence of the flow on the modulus of the pressure reflection coefficient is found to be well described by a theoretical prediction.
An implementation of discrete electron transport models for gold in the Geant4 simulation toolkit
NASA Astrophysics Data System (ADS)
Sakata, D.; Incerti, S.; Bordage, M. C.; Lampe, N.; Okada, S.; Emfietzoglou, D.; Kyriakou, I.; Murakami, K.; Sasaki, T.; Tran, H.; Guatelli, S.; Ivantchenko, V. N.
2016-12-01
Gold nanoparticle (GNP) boosted radiation therapy can enhance the biological effectiveness of radiation treatments by increasing the quantity of direct and indirect radiation-induced cellular damage. As the physical effects of GNP boosted radiotherapy occur across energy scales that descend down to 10 eV, Monte Carlo simulations require discrete physics models down to these very low energies in order to avoid underestimating the absorbed dose and secondary particle generation. Discrete physics models for electron transportation down to 10 eV have been implemented within the Geant4-DNA low energy extension of Geant4. Such models allow the investigation of GNP effects at the nanoscale. At low energies, the new models have better agreement with experimental data on the backscattering coefficient, and they show similar performance for transmission coefficient data as the Livermore and Penelope models already implemented in Geant4. These new models are applicable in simulations focussed towards estimating the relative biological effectiveness of radiation in GNP boosted radiotherapy applications with photon and electron radiation sources.
Radiation protection issues in galactic cosmic ray risk assessment
NASA Technical Reports Server (NTRS)
Sinclair, W. K.
1994-01-01
Radiation protection involves the limitation of exposure to below threshold doses for direct (or deterministic) effects and a knowledge of the risk of stochastic effects after low doses. The principal stochastic risk associated with low dose rate galactic cosmic rays is the increased risk of cancer. Estimates of this risk depend on two factors (a) estimates of cancer risk for low-LET radiation and (b) values of the appropriate radiation weighting factors, WR, for the high-LET radiations of galactic cosmic rays. Both factors are subject to considerable uncertainty. The low-LET cancer risk derived from the late effects of the atomic bombs is vulnerable to a number of uncertainties including especially that from projection in time, and from extrapolation from high to low dose rate. Nevertheless, recent low dose studies of workers and others tend to confirm these estimates. WR, relies on biological effects studied mainly in non-human systems. Additional laboratory studies could reduce the uncertainties in WR and thus produce a more confident estimate of the overall risk of galactic cosmic rays.
Radiation protection issues in galactic cosmic ray risk assessment.
Sinclair, W K
1994-01-01
Radiation protection involves the limitation of exposure to below threshold doses for direct (or deterministic) effects and a knowledge of the risk of stochastic effects after low doses. The principal stochastic risk associated with low dose rate galactic cosmic rays is the increased risk of cancer. Estimates of this risk depend on two factors (a) estimates of cancer risk for low-LET radiation and (b) values of the appropriate radiation weighting factors, WR, for the high-LET radiations of galactic cosmic rays. Both factors are subject to considerable uncertainty. The low-LET cancer risk derived from the late effects of the atomic bombs is vulnerable to a number of uncertainties including especially that from projection in time, and from extrapolation from high to low dose rate. Nevertheless, recent low dose studies of workers and others tend to confirm these estimates. WR, relies on biological effects studied mainly in non-human systems. Additional laboratory studies could reduce the uncertainties in WR and thus produce a more confident estimate of the overall risk of galactic cosmic rays.
Indirect effect of changing aerosol concentrations on methane and ozone radiative forcing
NASA Astrophysics Data System (ADS)
Rowlinson, Matthew; Rap, Alexandru; Arnold, Steve; Forster, Piers; Chipperfield, Martyn
2017-04-01
Atmospheric aerosols interact with climate in number of complex ways and quantifying the overall effect remains the dominant uncertainty in estimating anthropogenic climate forcing (IPCC, 2013). The radiative forcing (RF) caused by the direct effect of aerosol interacting with radiation is estimated at -0.35 (-0.85 to +0.15) Wm-2, while cloud-aerosol interactions are estimated at -0.45 (-1.2 to 0.0) Wm-2 (IPCC, 2013). The net impact is a cooling with an effective radiative forcing (ERF) of 0.9 (-1.9 to -0.1) Wm-2 (IPCC, 2013). One effect of aerosols which has not been well evaluated is their effect on atmospheric chemistry. Atmospheric aerosols provide a surface for homogeneous reactions to occur, altering reactions rates and the availability of oxidants, thereby influencing the removal/production of radiatively important species such as methane (CH4) and tropospheric ozone (O3). Oxidants such as the hydroxyl radical (OH) determine the atmospheric lifetime and hence burden of CH4, therefore changes to atmospheric aerosols which impact oxidation chemistry will also influence RF due to CH4. This effect could enhance or offset the negative RF of aerosols, depending on how the individual aerosol changes availability of oxidants. Quantifying the importance of this mechanism for RF is necessary to provide accurate estimates of the effect of aerosols, and assess relative effectiveness of measures to decrease aerosol emissions and precursors. Using a sophisticated aerosol micro-physics model (GLOMAP) coupled to the TOMCAT three-dimensional chemical transport model, we separately simulate changes in atmospheric composition resulting from a 50% decline in anthropogenic emissions of black carbon aerosol (BC), volatile organic compounds (VOCs) and anthropogenic precursors of sulphate and nitrate. The impact of changes to each aerosol on lifetime of CH4 is then calculated to establish the resulting impact on CH4 burden and RF. Cutting global anthropogenic SO2 emissions by 50% decreases atmospheric sulpate concentrations by 44% after 2 years, while increasing global OH concentrations by 0.9%. CH4 lifetime is reduced by approximately 50 days as a result, leading to a decrease in CH4 burden of 38ppb. NOx is anticipated to have a similar but much larger effect (Matsui and Koike 2016). The Edwards and Slingo offline radiation model is also used to calculate changes to direct and indirect aerosol forcing. Presented here is the net RF change following 50% emission decrease of each aerosol or precursors, accounting for the direct and indirect aerosol effect as well as indirect effects via oxidation chemistry on the RF due to CH4 and tropospheric O3.
Aerosol radiative effects and their trends under clear-sky situations over Europe
NASA Astrophysics Data System (ADS)
Bartok, Blanka
2017-04-01
In the literature great uncertainties ca be found regarding radiative effects of aerosols on the energy budget of the atmosphere (IPCC, 2013). In the study the aerosols radiative effects on clear-sky solar radiation are quantified over Europe using empirical and physical modelling approaches. The values of aerosol radiation effect are determined by the MAGIC radiation code. In the first run clear-sky radiation is calculated integrating KINEE/MPI/Aerocom aerosol climatology and ERA-INTERIM water vapour multiannual monthly means. In the next run the clear-sky radiation are also calculated ignoring aerosol data (adjusted to 0) from the algorithm. Both runs were carried out for each months of the year, taking into account the varying astrological factors. The difference between the aerosol-included and aerosol-free clear-sky radiation is equal to the absolute aerosol radiative effect in W/m2. The annual mean of the surface aerosol radiative effects in clear-sky situations over Europe is -7.1 ± 2.9 W/m2, high values are representing the central part of the continent and the Mediterranean Basin. Furthermore the trends of the aerosol radiative effects are also determined for the period of 2001-2012. First a linear fitting is elaborated between the aerosol optical depth (AOT) built in the MAGIC code and its aerosol radiative effect calculated by the code. Next, based on these linear functions a radiative effect values are assigned to each monthly AOT500 value available from the Moderate Resolution Imaging Spectroradiometer (MODIS) Terra Level-3 experiment. In this way a new dataset of aerosol radiative effect for the period of 2001-2012 has been created. Beside of this approach the changes in aerosol radiative effects are also calculated based on ground-based clear-sky radiation trends. This approach is used as a validation of the method applied in earlier stage, mainly for the linear fitting. The starting point of this approach is to elaborate the trends of clear-sky radiation controlled by the effects of aerosols and water vapour. If we subtract the water vapour effects also calculated by MAGIC radiation code from this trend, the magnitude of the trends in aerosol radiative effects can be estimated. In this case it is assumed that the two effects do not amplify and do not cancel each other, and their arithmetic sum gives the change in clear-sky radiation trend. The two approaches give good fit, based on the direct (modelled) approach the annual trend of the aerosol radiative effects on clear-sky solar surface radiation is -4.41 W/m2 per decade for the period of 2001-2013, while in the case of the indirect approach (based on clear-sky trends) this trend is found to be -4.46 W/m2 per decade.
Noise Radiation from Single and Multiple Rod Configurations
NASA Technical Reports Server (NTRS)
Hutcheson, Florence V.; Brooks, Thomas F.
2006-01-01
Acoustic measurements were performed on single and multiple rod configurations to study the effect of Reynolds number, surface roughness, freestream turbulence, proximity and wake interference on the radiated noise. The Reynolds number ranged from 3.8 x 10(exp 3) to 10(exp 5). Directivity measurements were performed to determine how well the dipole assumption for the radiation of vortex shedding noise holds for the different model configurations tested. The dependence of the peak Sound Pressure Level on velocity was also examined. Several concepts for the reduction of the noise radiating from cylindrical rods were tested. It was shown that wire wraps and collar distributions could be used to significantly reduce the noise radiating from rods in tandem configurations.
Exploring the observational constraints on the simulation of brown carbon
NASA Astrophysics Data System (ADS)
Wang, X.; Heald, C. L.; Liu, J.; Weber, R. J.; Campuzano-Jost, P.; Jimenez, J. L.; Schwarz, J. P.; Perring, A. E.
2017-12-01
Brown carbon (BrC) is the component of organic aerosols (OA) which strongly absorbs solar radiation in the near-UV range of the spectrum. However the sources, evolution, and optical properties of BrC remain highly uncertain, and therefore constitute a large source of uncertainty in estimating the global direct radiative effect (DRE) of aerosols. Previous modeling studies of BrC optical properties and DRE have been unable to fully evaluate the skill of their simulations, given the lack of direct measurements of organic aerosol absorption. In this study, we develop a global model simulation (GEOS-Chem) of BrC and test it against BrC absorption measurements from two aircraft campaigns in the U.S. (SEAC4RS and DC3). To our knowledge, this is the first study to compare simulated BrC absorption with direct, continuous ambient measurements. We show that the laboratory-based BrC absorption properties from biomass burning overestimate the aircraft measurements of ambient BrC. In addition, applying a photochemical whitening scheme to simulated BrC is better able to represent the observed BrC absorption. These observations are consistent with a mass absorption coefficient (MAC) of freshly emitted biomass burning OA of 0.57m2g-1. Using the RRTMG model integrated with GEOS-Chem, we estimate that the all-sky top-of-atmosphere direct radiative effect (DRE) of OA is -0.350 Wm-2, 10% higher than that without consideration of BrC absorption. Therefore, our best estimate of the absorption DRE of BrC is +0.042 Wm-2. We suggest that the DRE of BrC has been overestimated previously due to the lack of observational constraints from direct measurements as well as neglect of the effects of photochemical whitening.
In radiation biology, a bystander effect occurs when cells not directly exposed to ionizing radiation show increased genomic instability and impaired viability due to the release of signaling molecules by the irradiated cells in their vicinity. Christophe Redon, Ph.D., and colleagues in CCR’s Laboratory of Molecular Pharmacology, decided to ask whether a tumor itself could exhibit a similar effect. Their results were recently published in the Proceedings of the National Academy of Sciences.
Wang, Ren; Wang, Bing-Zhong; Huang, Wei-Ying; Ding, Xiao
2016-01-01
A compact reconfigurable antenna with an omnidirectional mode and four directional modes is proposed. The antenna has a main radiator and four parasitic elements printed on a dielectric substrate. By changing the status of diodes soldered on the parasitic elements, the proposed antenna can generate four directional radiation patterns and one omnidirectional radiation pattern. The main beam directions of the four directional modes are almost orthogonal and the four directional beams can jointly cover a 360° range in the horizontal plane, i.e., the main radiation plane of omnidirectional mode. The whole volume of the antenna and the control network is approximately 0.70 λ × 0.53 λ × 0.02 λ, where λ is the wavelength corresponding to the center frequency. The proposed antenna has a simple structure and small dimensions under the requirement that the directional radiation patterns can jointly cover the main radiation plane of the omnidirectional mode, therefore, it can be used in smart wireless sensor systems for different application scenarios. PMID:27092512
Nano-structured wild moth cocoon fibers as radiative cooling and waveguiding optical materials
NASA Astrophysics Data System (ADS)
Shi, Norman Nan; Tsai, Cheng-Chia; Bernard, Gary D.; Craig, Catherine; Yu, Nanfang
2017-09-01
The study shows that comet moth cocoon fibers exhibit radiative cooing properties with enhanced solar reflectivity and thermal emissivity. Nanostructured voids inside the cocoon fiber enables the cocoons to exhibit strong scattering in the visible and near-infrared. These structures also allow the fibers to exhibit strong shape birefringence and directional reflectivity. Optical waveguiding due to transverse Anderson localization is observed in these natural fibers, where the invariance and large concentration of the voids in the longitudinal direction allow the fiber to confine light in the transverse direction. To mimic the optical effects generated by these natural silk fibers, nanostructured voids are introduced into regenerated silk fibers through wet spinning to enhance reflectivity in the solar spectrum.
NASA Technical Reports Server (NTRS)
Ponchak, George E.; Jordan, Jennifer L.; Chevalier, Christine T.
2006-01-01
The characteristics of a double exponentially tapered slot antenna (DETSA) as a function of the radius that the DETSA is conformed to in the longitudinal direction is presented. It is shown through measurements and simulations that the radiation pattern of the conformed antenna rotates in the direction through which the antenna is curved, and that diffraction affects the radiation pattern if the radius of curvature is too small or the frequency too high. The gain of the antenna degrades by only 1 dB if the radius of curvature is large and more than 2 dB for smaller radii. The main effect due to curving the antenna is an increased cross-polarization in the E-plane.
Spectral and Polarimetric Imagery Collection Experiment
2011-12-01
meter Visibility Smoke, fog, haze Pyranometer Sun and sky radiation Pryheliometer Solar radiation direction Required tracking mount Distrometer(s... Pyranometers measure total sun and sky radiation. If the direction of the solar radiation is an important factor, then use of a normal incidence
Effect of Swirl on Turbulent Structures in Supersonic Jets
NASA Technical Reports Server (NTRS)
Rao, Ram Mohan; Lundgren, Thomas S.
1998-01-01
Direct Numerical Simulation (DNS) is used to study the mechanism of generation and evolution of turbulence structures in a temporally evolving supersonic swirling round jet and also to examine the resulting acoustic radiations. Fourier spectral expansions are used in the streamwise and azimuthal directions and a 1-D b-spline Galerkin representation is used in the radial direction. Spectral-like accuracy is achieved using this numerical scheme. Direct numerical simulations, using the b-spline spectral method, are carried out starting from mean flow initial conditions which are perturbed by the most unstable linear stability eigenfunctions. It is observed that the initial helical instability waves evolve into helical vortices which eventually breakdown into smaller scales of turbulence. 'Rib' structures similar to those seen in incompressible mixing layer flow of Rogers and Moserl are observed. The jet core breakdown stage exhibits increased acoustic radiations.
Direct Radiative Effect of Intense Dust Outbreaks in the Mediterranean
NASA Astrophysics Data System (ADS)
Gkikas, A.; Obiso, V.; Basart, S.; Jorba, O.; Pérez García-Pando, C.; Hatzianastassiou, N.; Gassó, S.; Baldasano, J. M.
2015-12-01
The broader Mediterranean basin is affected by intense desert dust outbreaks in spring. In the present study, we make use of satellite observations and modelling to investigate dust radiative impacts during three consecutive dust outbreaks occurred over the Mediterranean in the period 9/4-15/4/2008. The direct radiative effect (DRE) is estimated by using two simulations run with the NMMB/BSC-Dust model, where the interaction between dust aerosols and radiation is activated and deactivated, respectively. The simulation domain covers the North Africa, the Middle East and Europe at 0.25ºx0.25° and 40σ-layers. The first outbreak took place over the central and eastern Mediterranean on the 9th reaching aerosol optical depths (AODs) close to 1. The second one, with AODs up to 2, lasted from 10th to 14th affecting mainly the central Mediterranean. The third one, with AODs up to 5, affected the Iberian Peninsula on the 15th. DREs are computed for the outgoing radiation at the top of the atmosphere (TOA), the absorbed radiation into the atmosphere (ATMAB), for the downwelling (SURF) and the absorbed (NETSURF) radiation at surface, for the shortwave (SW), longwave (LW) and NET (SW+LW) radiation. According to our results, it is evident that DREs' spatial patterns are driven by those of AOD. Negative (cooling) instantaneous DRETOA, DRESURF and DRENETSURF values up to -500W/m2, -700W/m2 and -600W/m2, respectively, and positive (warming) instantaneous DREATMAB up to 340W/m2 are found for the SW spectrum, during daytime. Opposite but less pronounced effects are encountered for the LW radiation and during nightime. Due to these perturbations on the radiation field, the surface temperature is reduced locally by up to 8°C during daytime and increased by up to 4°C during nightime. It is found that the regional average NET DREs can be as large as -12W/m2, -45W/m2, -30W/m2 and 27W/m2 for TOA, SURF, NETSURF and ATMAB, respectively. Impacts on atmospheric stability and dust emissions are also investigated.
Characterization of a novel epigenetic effect of ionizing radiation: the death-inducing effect
NASA Technical Reports Server (NTRS)
Nagar, Shruti; Smith, Leslie E.; Morgan, William F.
2003-01-01
The detrimental effects associated with exposure to ionizing radiation have long been thought to result from the direct targeting of the nucleus leading to DNA damage; however, the emergence of concepts such as radiation-induced genomic instability and bystander effects have challenged this dogma. After cellular exposure to ionizing radiation, we have isolated a number of clones of Chinese hamster-human hybrid GM10115 cells that demonstrate genomic instability as measured by chromosomal destabilization. These clones show dynamic and persistent generation of chromosomal rearrangements multiple generations after the original insult. We hypothesize that these unstable clones maintain this delayed instability phenotype by secreting factors into the culture medium. To test this hypothesis we transferred filtered medium from unstable cells to unirradiated GM10115 cells. No GM10115 cells were able to survive this medium. This phenomenon by which GM10115 cells die when cultured in medium from chromosomally unstable GM10115 clones is the death-inducing effect. Medium transfer experiments indicate that a factor or factors is/are secreted by unstable cells within 8 h of growth in fresh medium and result in cell killing within 24 h. These factors are stable at ambient temperature but do not survive heating or freezing, and are biologically active when diluted with fresh medium. We present the initial description and characterization of the death-inducing effect. This novel epigenetic effect of radiation has implications for radiation risk assessment and for health risks associated with radiation exposure.
Iatrogenic radiation exposure to patients with early onset spine and chest wall deformities.
Khorsand, Derek; Song, Kit M; Swanson, Jonathan; Alessio, Adam; Redding, Gregory; Waldhausen, John
2013-08-01
Retrospective cohort series. Characterize average iatrogenic radiation dose to a cohort of children with thoracic insufficiency syndrome (TIS) during assessment and treatment at a single center with vertically expandable prosthetic titanium rib. Children with TIS undergo extensive evaluations to characterize their deformity. No standardized radiographical evaluation exists, but all reports use extensive imaging. The source and level of radiation these patients receive is not currently known. We evaluated a retrospective consecutive cohort of 62 children who had surgical treatment of TIS at our center from 2001-2011. Typical care included obtaining serial radiographs, spine and chest computed tomographic (CT) scans, ventilation/perfusion scans, and magnetic resonance images. Epochs of treatment were divided into time of initial evaluation to the end of initial vertically expandable prosthetic titanium rib implantation with each subsequent epoch delineated by the next surgical intervention. The effective dose for each examination was estimated within millisieverts (mSv). Plain radiographs were calculated from references. Effective dose was directly estimated for CT scans since 2007 and an average of effective dose from 2007-2011 was used for scans before 2007. Effective dose from fluoroscopy was directly estimated. All doses were reported in mSv. A cohort of 62 children had a total of 447 procedures. There were a total of 290 CT scans, 4293 radiographs, 147 magnetic resonance images, and 134 ventilation/perfusion scans. The average accumulated effective dose was 59.6 mSv for children who had completed all treatment, 13.0 mSv up to initial surgery, and 3.2 mSv for each subsequent epoch of treatment. CT scans accounted for 74% of total radiation dose. Children managed for TIS using a consistent protocol received iatrogenic radiation doses that were on average 4 times the estimated average US background radiation exposure of 3 mSv/yr. CT scans comprised 74% of the total dose. 3.
NASA Technical Reports Server (NTRS)
Pecaut, Michael J.; Haerich, Paul; Zuccarelli, Cara N.; Smith, Anna L.; Zendejas, Eric D.; Nelson, Gregory A.
2002-01-01
Two experiments were carried out to investigate the consequences of exposure to proton radiation, such as might occur for astronauts during space flight. C57BL/6 mice were exposed, either with or without 15-g/cm2 aluminum shielding, to 0-, 3-, or 4-Gy proton irradiation mimicking features of a solar particle event. Irradiation produced transient direct deficits in open-field exploratory behavior and acoustic startle habituation. Rotorod performance at 18 rpm was impaired by exposure to proton radiation and was impaired at 26 rpm, but only for mice irradiated with shielding and at the 4-Gy dose. Long-term (>2 weeks) indirect deficits in open-field activity appeared as a result of impaired experiential encoding immediately following exposure. A 2-week recovery prior to testing decreased most of the direct effects of exposure, with only rotorod performance at 26 rpm being impaired. These results suggest that the performance deficits may have been mediated by radiation damage to hippocampal, cerebellar, and possibly, forebrain dopaminergic function.
The total ozone and UV solar radiation over Stara Zagora, Bulgaria
NASA Astrophysics Data System (ADS)
Mendeva, B.; Gogosheva, Ts.; Petkov, B.; Krastev, D.
Direct ground-based UV measurements and the total ozone content (TOC) over Stara Zagora, Bulgaria are presented. The observations are conducted by a scanning spectrophotometer, which measures the direct solar radiation in the range 290 - 360 nm with 1 nm resolution. For the time period 1998 -- 2003 the TOC data show seasonal variations, typical for the middle latitudes -- maximum in the spring and minimum in the autumn. The comparison of these TOC ground-based data to TOC satellite-borne data from the Global Ozone Monitoring Experiment (GOME) shows a seasonal dependence of the differences between the ground-based and satellite data. The relation between the UV radiation and TOC is investigated. Clear negative relationship is recognized between the total ozone and the irradiance of the wavelength 305 nm. The opposition of the two variables is significant ( r = - 0,62 ± 0,18) at 98 % confidence level. Yet, for 325 nm it is almost independent with the total ozone. The dependence of the UV-B radiation on the solar zenith angle at given TOC is also analyzed. A decrease of all wavelengths intensities with increase of the solar zenith angle is obtained but with different rate for each of them. The direct sun UV doses for some specific biological effects (erythema and eyes) are obtained as the integral in the wavelength interval 290-330 nm of the measured UV solar spectrum, weighted with an action spectrum, typical for each effect. The estimation of the radiation amplification factor RAF shows that the ozone reduction by 1% increases the erythemal dose by 2,3 %.The eye-damaging doses are more influenced by the TOC changes and in this case RAF=-2,7%. The amount of these biological doses is in a direct ratio with the solar altitude over the horizon. This dependence is more markedly expressed at lower total ozone content in the atmosphere.
Frankel, Arthur
2015-01-01
The decay of the Fourier spectral amplitudes of S waves over distances of 10–80 km near Charlevoix, Quebec, was determined using waveforms from seven earthquakes with MN 3.3–5.4. The S‐wave spectral amplitudes were corrected for site response and source amplitude by normalizing the coda‐wave spectrum at a fixed time after the origin time. The amplitude decay with distance was found to be less steep as the frequency increases from 1 to 14, contrary to what would be expected from anelastic and scattering attenuation for a point source with an isotropic radiation pattern. The decay at 14 Hz indicates that the geometrical spreading at distances less than 80 km is less steep than R−1.05. The steeper distance decay of the low‐frequency spectrum appears to be an artifact of the radiation pattern and rupture directivity, which affect the low‐frequency amplitude more than the high frequency. Synthetic seismograms were made for a horizontally layered crust for the Mw 4.6 Rivière du Loup earthquake and an Mw 3.3 event. The decay with distance of the 1 Hz spectral amplitudes of the synthetics is similar to that observed for the Rivière du Loup earthquake, indicating that radiation pattern and rupture directivity are important factors in determining the attenuation with distance at 1 Hz. For the Mw 3.3 earthquake, the distance decay of the 1 Hz spectral amplitudes was found to be sensitive to the focal mechanism. This study demonstrates that estimates of geometrical spreading made using 1 Hz amplitudes can be contaminated by radiation pattern and directivity effects and may not be applicable for constructing ground‐motion prediction equations for sources with other focal mechanisms and rupture behavior.
Estimating on-orbit optical properties for GNSS satellites
NASA Astrophysics Data System (ADS)
Rodriguez Solano, M. Sc. Carlos Javier; Hugentobler, Urs; Steigenberger, Peter
One of the major uncertainty sources affecting GNSS satellite orbits is the direct solar radiation pressure. Other important though smaller effects are caused by deviations of the satellite from nominal attitude, Earth radiation pressure and thermal re-radiation forces. To compensate such effects, the IGS Analysis Centers usually estimate empirical parameters which fit best the tracking data obtained from a global network of GNSS ground stations to compute orbits at an accuracy level of 2.5 cm for GPS and of 5 cm for GLONASS. On the other hand, there are also accurate physical models for the above mentioned non-conservative forces affecting the GNSS satellites such as the ROCK models for GPS satellites. However, current models fail to predict the real orbit behaviour with sufficient accuracy, mainly due to deviations from nominal attitude, from inaccurately known optical properties, or from aging of the satellite surfaces. In this context an analytical box-wing model has been derived based on the physical interaction between the direct solar radiation and a satellite consisting of a bus (box shape) and solar panels. Furthermore some of the parameters of the box-wing model can be adjusted to fit the GNSS tracking data, namely the fraction of reflected photons of the corresponding satellite surfaces. For this study GNSS orbits are generated based on one year of tracking data from the global IGS network and involving the box-wing model implemented into the Bernese GPS Software. The processing scheme was derived from the one used at the Center for Orbit Determination in Europe (CODE). The resulting satellite orbits are compared with CODE Final Orbits and validated using SLR (Satellite Laser Ranging) tracking data. Additionally, in the case of GPS satellites, the box-wing model and the obtained optical properties are compared directly with a priori models (e.g. ROCK), which deal with the direct solar radiation impacting the satellites.
Differences Between ERBE and CERES Tropical Means Fluxes: ENSO, Climate Change of Calibration?
NASA Technical Reports Server (NTRS)
Wielicki, Bruce A.; Wong, Takmeng; Young, David F.; Barkstrom, Bruce R.; Lee, R. B., III; Haeffelin, Martial
1999-01-01
Verner E. Soumi was the father of radiation budget measurements from space. He directed the team at the University of Wisconsin that developed the first radiation budget measurements on the Iota (Explorer VII) coverage) spacecraft in 1959. The first data published was from hand calculations of night-time long-wave fluxes, with absolute accuracy estimated as better than 10 percent, and the data shown as hand drawn maps with lines of equal "long-wave radiation loss, in Langleys per minute X 10(exp -3) (isolangleys)". The first comparisons of the new radiation data with nephanalyses showed that clouds dominated the radiation patterns. Soumi immediately proposed using the radiation fields to help understand the atmospheric heat sources necessary to drive the atmospheric circulation. This early work already pointed to the relationship between the outgoing longwave radiation at the top of the atmosphere and the vertical flux divergence of infrared radiation within the atmosphere. In the next 30 years, global satellite observations of the radiation balance of the planet have advanced both in accuracy, stability, and in their ability to address cause and effect in the climate system. The purpose of the present paper is to examine early results of the new Clouds and the Earth's Radiant Energy System (CERES) data on Tropical Rainfall Measuring System (TRMM) which started data collection in January, 1998. CERES is a direct descendant of the legacy of Soumi's foresight on understanding the global energetics using satellite observations of broadband radiation.
Differences between ERBE and CERES Tropical Mean Fluxes: ENSO, Climate Change or Calibration?
NASA Technical Reports Server (NTRS)
Wielicki, Bruce A.; Wong, Takmeng; Young, David F.; Barkstrom, Bruce R.; Lee, R. B., III; Haeffelin, Martial
2005-01-01
Verner E. Soumi was the father of radiation budget measurements from space. He directed the team at the University of Wisconsin that developed the first radiation budget measurements on the Iota (Explorer VII) coverage) spacecraft in 1959. The first data published was from hand calculations of night-time long-wave fluxes, with absolute accuracy estimated as better than 10 percent, and the data shown as hand drawn maps with lines of equal "long-wave radiation loss, in Langleys per minute X 10(exp -3) (isolangleys)". The first comparisons of the new radiation data with nephanalyses showed that clouds dominated the radiation patterns. Soumi immediately proposed using the radiation fields to help understand the atmospheric heat sources necessary to drive the atmospheric circulation. This early work already pointed to the relationship between the outgoing longwave radiation at the top of the atmosphere and the vertical flux divergence of infrared radiation within the atmosphere. In the next 30 years, global satellite observations of the radiation balance of the planet have advanced both in accuracy, stability, and in their ability to address cause and effect in the climate system. The purpose of the present paper is to examine early results of the new Clouds and the Earth's Radiant Energy System (CERES) data on Tropical Rainfall Measuring System (TRMM) which started data collection in January, 1998. CERES is a direct descendant of the legacy of Soumi's foresight on understanding the global energetics using satellite observations of broadband radiation.
Acevedo-Duncan, M; Pearlman, J; Zachariah, B
2001-02-01
We assessed the radiosensitivity of the grade III human glioma cell line U-373MG by investigating the effects of radiation and the specific protein kinase C inhibitor, calphostin C on the cell cycle and cell proliferation. Irradiated glioma U-373MG cells progressed through G1-S and underwent an arrest in G2-M phase. The radiosensitivity of U-373MG cells to graded doses of either photons or electrons was determine by microculture tetrazolium assay. The data was fitted to the linear-quadratic model. The proliferation curves demonstrated that U-373MG cells appear to be highly radiation resistant since 8 Gy was required to achieve 50% cell mortality. Compared to radiation alone, exposure to calphostin C (250 nM) 1 h prior to radiation decreased the proliferation of U-373MG by 76% and calphostin C provoked a weakly synergistic effect in concert with radiation. Depending on the time of application following radiation, calphostin C produced an additive or less than additive effect on cell proliferation. We postulate that the enhanced radiosensitivity observed when cells are exposed to calphostin C prior to radiation may be due to direct or indirect inhibition of protein kinase C isozymes required for cell cycle progression.
Feedbacks between air pollution and weather, Part 1: Effects on weather
NASA Astrophysics Data System (ADS)
Makar, P. A.; Gong, W.; Milbrandt, J.; Hogrefe, C.; Zhang, Y.; Curci, G.; Žabkar, R.; Im, U.; Balzarini, A.; Baró, R.; Bianconi, R.; Cheung, P.; Forkel, R.; Gravel, S.; Hirtl, M.; Honzak, L.; Hou, A.; Jiménez-Guerrero, P.; Langer, M.; Moran, M. D.; Pabla, B.; Pérez, J. L.; Pirovano, G.; San José, R.; Tuccella, P.; Werhahn, J.; Zhang, J.; Galmarini, S.
2015-08-01
The meteorological predictions of fully coupled air-quality models running in ;feedback; versus ;no-feedback; simulations were compared against each other and observations as part of Phase 2 of the Air Quality Model Evaluation International Initiative. In the ;no-feedback; mode, the aerosol direct and indirect effects were disabled, with the models reverting to either climatologies of aerosol properties, or a no-aerosol weather simulation. In the ;feedback; mode, the model-generated aerosols were allowed to modify the radiative transfer and/or cloud formation parameterizations of the respective models. Annual simulations with and without feedbacks were conducted on domains over North America for the years 2006 and 2010, and over Europe for the year 2010. The incorporation of feedbacks was found to result in systematic changes to forecast predictions of meteorological variables, both in time and space, with the largest impacts occurring in the summer and near large sources of pollution. Models incorporating only the aerosol direct effect predicted feedback-induced reductions in temperature, surface downward and upward shortwave radiation, precipitation and PBL height, and increased upward shortwave radiation, in both Europe and North America. The feedback response of models incorporating both the aerosol direct and indirect effects varied across models, suggesting the details of implementation of the indirect effect have a large impact on model results, and hence should be a focus for future research. The feedback response of models incorporating both direct and indirect effects was also consistently larger in magnitude to that of models incorporating the direct effect alone, implying that the indirect effect may be the dominant process. Comparisons across modelling platforms suggested that direct and indirect effect feedbacks may often act in competition: the sign of residual changes associated with feedbacks often changed between those models incorporating the direct effect alone versus those incorporating both feedback processes. Model comparisons to observations for no-feedback and feedback implementations of the same model showed that differences in performance between models were larger than the performance changes associated with implementing feedbacks within a given model. However, feedback implementation was shown to result in improved forecasts of meteorological parameters such as the 2 m surface temperature and precipitation. These findings suggest that meteorological forecasts may be improved through the use of fully coupled feedback models, or through incorporation of improved climatologies of aerosol properties, the latter designed to include spatial, temporal and aerosol size and/or speciation variations.
The direct effect of aerosols on solar radiation over the broader Mediterranean basin
NASA Astrophysics Data System (ADS)
Papadimas, C. D.; Hatzianastassiou, N.; Matsoukas, C.; Kanakidou, M.; Mihalopoulos, N.; Vardavas, I.
2012-08-01
For the first time, the direct radiative effect (DRE) of aerosols on solar radiation is computed over the entire Mediterranean basin, one of the most climatically sensitive world regions, using a deterministic spectral radiation transfer model (RTM). The DRE effects on the outgoing shortwave radiation at the top of atmosphere (TOA), DRETOA, on the absorption of solar radiation in the atmospheric column, DREatm, and on the downward and absorbed surface solar radiation (SSR), DREsurf and DREnetsurf, respectively, are computed separately. The model uses input data for the period 2000-2007 for various surface and atmospheric parameters, taken from satellite (International Satellite Cloud Climatology Project, ISCCP-D2), Global Reanalysis projects (National Centers for Environmental Prediction - National Center for Atmospheric Research, NCEP/NCAR), and other global databases. The spectral aerosol optical properties (aerosol optical depth, AOD, asymmetry parameter, gaer and single scattering albedo, ωaer), are taken from the MODerate resolution Imaging Spectroradiometer (MODIS) of NASA (National Aeronautics and Space Administration) and they are supplemented by the Global Aerosol Data Set (GADS). The model SSR fluxes have been successfully validated against measurements from 80 surface stations of the Global Energy Balance Archive (GEBA) covering the period 2000-2007. A planetary cooling is found above the Mediterranean on an annual basis (regional mean DRETOA = -2.4 W m-2). Although a planetary cooling is found over most of the region, of up to -7 W m-2, large positive DRETOA values (up to +25 W m-2) are found over North Africa, indicating a strong planetary warming, and a weaker warming over the Alps (+0.5 W m-2). Aerosols are found to increase the absorption of solar radiation in the atmospheric column over the region (DREatm = +11.1 W m-2) and to decrease SSR (DREsurf = -16.5 W m-2 and DREnetsurf-13.5 W m-2) inducing thus significant atmospheric warming and surface radiative cooling. The calculated seasonal and monthly DREs are even larger, reaching -25.4 W m-2 (for DREsurf). Within the range of observed natural or anthropogenic variability of aerosol optical properties, AOD seems to be the main responsible parameter for modifications of regional aerosol radiative effects, which are found to be quasi-linearly dependent on AOD, ωaer and gaer.
An Investigation of the Effects of Black Carbon on Precipitation in the Western United States
NASA Astrophysics Data System (ADS)
Tseng, Hsien-Liang Rose
Black carbon (BC), the byproduct of incomplete combustion, is considered to be the second most important anthropogenic climate forcing agent after carbon dioxide. BC warms the atmosphere by absorbing solar radiation (direct effect), alters cloud and precipitation formation by acting as cloud condensation nuclei (indirect effect), and modifies cloud distribution via cloud burn-off (semi-direct effect). Currently, there are large discrepancies in general circulation model estimates of the influence of BC on precipitation. Even less known is how BC changes precipitation on regional scales. In the drought-stricken western United States (WUS), where BC emissions are known to affect the hydrological cycle, an investigation on how BC influences precipitation is warranted. In this study, we employ the Weather Research and Forecasting-Chemistry (WRF Chem) model (version 3.6.0) with the newly chemistry- and microphysics-coupled Fu-Liou-Gu radiation scheme to study how black carbon affects precipitation by separating BC-related effects into direct and semi-direct, and indirect effects. In this three-part study, we use a recent wet year (2005) to investigate black carbon effects. We first examine BC effects during a heavy wintertime heavy precipitation event (7-11 January 2005), a heavy summertime precipitation week for comparison to the wintertime event (20-24 July 2005), and finally, examine these same effects for the months of January to June 2005 to investigate month-long trends. We find that BC suppresses precipitation, predominantly through its direct and semi-direct effects. The direct and semi-direct effects warm the air aloft, and cool the lower levels of the atmosphere (surface dimming) through the reduction of downward shortwave radiation flux at the surface. These changes in vertical temperature increase the stability of the atmosphere and reduce convective precipitation. Convective precipitation reduction accounts for approximately 60 75% of the total precipitation reduction. Additionally, cooling in the lower levels reduces evaporation from the surface, which reduces the moisture needed for non-convective precipitation. Subsequently, reduced moisture in the atmosphere suppresses non-convective precipitation by approximately 10-40%. The indirect effects also reduce precipitation, but to a much smaller extent of 5-20%. Although we use an atypical BC emission dataset is used in this study, the resulting reduction of the different types of precipitation sheds light on the physical mechanisms of BC-cloud-radiation interactions by which the reductions follow. In particular, our results highlight the importance of the cumulus and surface layer parameterizations that house the triggering mechanism and surface moisture flux parameterizations in future studies. In this research we find the NEI 2005 emissions did not significantly change precipitation. This is likely due to the aggressive emission regulations that exist for the United States. Emission regulations, however, do not exist or are enforced equally across the globe. In the developing countries that rely on inefficient cook stoves and heating systems, the populations suffer the most due to black carbon emission. Along with respiratory and cardiovascular impacts from black carbon, they may suffer from reduced water resources from suppressed precipitation, as well. In a larger sense, findings from this research serve as a platform for understanding the wider-reaching effects of black carbon on regional precipitation and drought. In particular, in areas where there are no black carbon emission regulations, this would highlight health and potentially significant environmental benefits that could be achieved from a black carbon cap and trade.
Changes in domestic heating fuel use in Greece: effects on atmospheric chemistry and radiation
NASA Astrophysics Data System (ADS)
Athanasopoulou, Eleni; Speyer, Orestis; Brunner, Dominik; Vogel, Heike; Vogel, Bernhard; Mihalopoulos, Nikolaos; Gerasopoulos, Evangelos
2017-09-01
For the past 8 years, Greece has been experiencing a major financial crisis which, among other side effects, has led to a shift in the fuel used for residential heating from fossil fuel towards biofuels, primarily wood. This study simulates the fate of the residential wood burning aerosol plume (RWB smog) and the implications on atmospheric chemistry and radiation, with the support of detailed aerosol characterization from measurements during the winter of 2013-2014 in Athens. The applied model system (TNO-MACC_II emissions and COSMO-ART model) and configuration used reproduces the measured frequent nighttime aerosol spikes (hourly PM10 > 75 µg m-3) and their chemical profile (carbonaceous components and ratios). Updated temporal and chemical RWB emission profiles, derived from measurements, were used, while the level of the model performance was tested for different heating demand (HD) conditions, resulting in better agreement with measurements for Tmin < 9 °C. Half of the aerosol mass over the Athens basin is organic in the submicron range, of which 80 % corresponds to RWB (average values during the smog period). Although organic particles are important light scatterers, the direct radiative cooling of the aerosol plume during wintertime is found low (monthly average forcing of -0.4 W m-2 at the surface), followed by a minor feedback to the concentration levels of aerosol species. The low radiative cooling of a period with such intense air pollution conditions is attributed to the timing of the smog plume appearance, both directly (longwave radiation increases during nighttime) and indirectly (the mild effect of the residual plume on solar radiation during the next day, due to removal and dispersion processes).
NASA Technical Reports Server (NTRS)
Fox, Robert; Prins, Elaine Mae; Feltz, Joleen M.
2001-01-01
In recent years, modeling and analysis efforts have suggested that the direct and indirect radiative effects of both anthropogenic and natural aerosols play a major role in the radiative balance of the earth and are an important factor in climate change calculations. The direct effects of aerosols on radiation and indirect effects on cloud properties are not well understood at this time. In order to improve the characterization of aerosols within climate models it is important to accurately parameterize aerosol forcing mechanisms at the local, regional, and global scales. This includes gaining information on the spatial and temporal distribution of aerosols, transport regimes and mechanisms, aerosol optical thickness, and size distributions. Although there is an expanding global network of ground measurements of aerosol optical thickness and size distribution at specific locations, satellite data must be utilized to characterize the spatial and temporal extent of aerosols and transport regimes on regional and global scales. This study was part of a collaborative effort to characterize aerosol radiative forcing over the Atlantic basin associated with the following three major aerosol components in this region: urban/sulfate, Saharan dust, and biomass burning. In-situ ground measurements obtained by a network of sun photometers during the Smoke Clouds and Radiation Experiment in Brazil (SCAR-B) and the Tropospheric Aerosol Radiative Forcing Observational Experiment (TARFOX) were utilized to develop, calibrate, and validate a Geostationary Operational Environmental Satellite (GOES)-8 aerosol optical thickness (AOT) product. Regional implementation of the GOES-8 AOT product was used to augment point source measurements to gain a better understanding of the spatial and temporal distributions of Atlantic basin aerosols during SCAR-B and TARFOX.
NASA Technical Reports Server (NTRS)
Plante, I; Wu, H
2014-01-01
The code RITRACKS (Relativistic Ion Tracks) has been developed over the last few years at the NASA Johnson Space Center to simulate the effects of ionizing radiations at the microscopic scale, to understand the effects of space radiation at the biological level. The fundamental part of this code is the stochastic simulation of radiation track structure of heavy ions, an important component of space radiations. The code can calculate many relevant quantities such as the radial dose, voxel dose, and may also be used to calculate the dose in spherical and cylindrical targets of various sizes. Recently, we have incorporated DNA structure and damage simulations at the molecular scale in RITRACKS. The direct effect of radiations is simulated by introducing a slight modification of the existing particle transport algorithms, using the Binary-Encounter-Bethe model of ionization cross sections for each molecular orbitals of DNA. The simulation of radiation chemistry is done by a step-by-step diffusion-reaction program based on the Green's functions of the diffusion equation]. This approach is also used to simulate the indirect effect of ionizing radiation on DNA. The software can be installed independently on PC and tablets using the Windows operating system and does not require any coding from the user. It includes a Graphic User Interface (GUI) and a 3D OpenGL visualization interface. The calculations are executed simultaneously (in parallel) on multiple CPUs. The main features of the software will be presented.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sunavala-Dossabhoy, Gulshan, E-mail: gsunav@lsuhsc.edu; Palaniyandi, Senthilnathan; Richardson, Charles
2012-09-01
Purpose: Patients treated with radiotherapy for head-and-neck cancer invariably suffer its deleterious side effect, xerostomia. Salivary hypofunction ensuing from the irreversible destruction of glands is the most common and debilitating oral complication affecting patients undergoing regional radiotherapy. Given that the current management of xerostomia is palliative and ineffective, efforts are now directed toward preventive measures to preserve gland function. The human homolog of Tousled protein, TLK1B, facilitates chromatin remodeling at DNA repair sites and improves cell survival against ionizing radiation (IR). Therefore, we wanted to determine whether a direct transfer of TLK1B protein to rat salivary glands could protect againstmore » IR-induced salivary hypofunction. Methods: The cell-permeable TAT-TLK1B fusion protein was generated. Rat acinar cell line and rat salivary glands were pretreated with TAT peptide or TAT-TLK1B before IR. The acinar cell survival in vitro and salivary function in vivo were assessed after radiation. Results: We demonstrated that rat acinar cells transduced with TAT-TLK1B were more resistant to radiation (D{sub 0} = 4.13 {+-} 1.0 Gy; {alpha}/{beta} = 0 Gy) compared with cells transduced with the TAT peptide (D{sub 0} = 4.91 {+-} 1.0 Gy; {alpha}/{beta} = 20.2 Gy). Correspondingly, retroductal instillation of TAT-TLK1B in rat submandibular glands better preserved salivary flow after IR (89%) compared with animals pretreated with Opti-MEM or TAT peptide (31% and 39%, respectively; p < 0.01). Conclusions: The results demonstrate that a direct transfer of TLK1B protein to the salivary glands effectively attenuates radiation-mediated gland dysfunction. Prophylactic TLK1B-protein therapy could benefit patients undergoing radiotherapy for head-and-neck cancer.« less
NASA Astrophysics Data System (ADS)
Mai, Boru; Deng, Xuejiao; Li, Zhanqing; Liu, Jianjun; Xia, Xiang'ao; Che, Huizheng; Liu, Xia; Li, Fei; Zou, Yu; Cribb, Maureen
2018-02-01
Aerosol optical properties and direct radiative effects on surface irradiance were examined using seven years (2006-2012) of Cimel sunphotometer data collected at Panyu—the main atmospheric composition monitoring station in the Pearl River Delta (PRD) region of China. During the dry season (October to February), mean values of the aerosol optical depth (AOD) at 550 nm, the Ångström exponent, and the single scattering albedo at 440 nm (SSA) were 0.54, 1.33 and 0.87, respectively. About 90% of aerosols were dominated by fine-mode strongly absorbing particles. The size distribution was bimodal, with fine-mode particles dominating. The fine mode showed a peak at a radius of 0.12 μm in February and October (˜ 0.10 μm3μm-2). The mean diurnal shortwave direct radiative forcing at the surface, inside the atmosphere ( F ATM), and at the top of the atmosphere, was -33.4±7.0, 26.1±5.6 and -7.3±2.7Wm-2, respectively. The corresponding mean values of aerosol direct shortwave radiative forcing per AOD were -60.0 ± 7.8, 47.3 ± 8.3 and -12.8 ± 3.1 W m-2, respectively. Moreover, during the study period, F ATM showed a significant decreasing trend ( p < 0.01) and SSA increased from 0.87 in 2006 to 0.91 in 2012, suggesting a decreasing trend of absorbing particles being released into the atmosphere. Optical properties and radiative impacts of the absorbing particles can be used to improve the accuracy of inversion algorithms for satellite-based aerosol retrievals in the PRD region and to better constrain the climate effect of aerosols in climate models.
The use of an active controlled enclosure to attenuate sound radiation from a heavy radiator
NASA Astrophysics Data System (ADS)
Sun, Yao; Yang, Tiejun; Zhu, Minggang; Pan, Jie
2017-03-01
Active structural acoustical control usually experiences difficulty in the control of heavy sources or sources where direct applications of control forces are not practical. To overcome this difficulty, an active controlled enclosure, which forms a cavity with both flexible and open boundary, is employed. This configuration permits indirect implementation of active control in which the control inputs can be applied to subsidiary structures other than the sources. To determine the control effectiveness of the configuration, the vibro-acoustic behavior of the system, which consists of a top plate with an open, a sound cavity and a source panel, is investigated in this paper. A complete mathematical model of the system is formulated involving modified Fourier series formulations and the governing equations are solved using the Rayleigh-Ritz method. The coupling mechanisms of a partly opened cavity and a plate are analysed in terms of modal responses and directivity patterns. Furthermore, to attenuate sound power radiated from both the top panel and the open, two strategies are studied: minimizing the total radiated power and the cancellation of volume velocity. Moreover, three control configurations are compared, using a point force on the control panel (structural control), using a sound source in the cavity (acoustical control) and applying hybrid structural-acoustical control. In addition, the effects of boundary condition of the control panel on the sound radiation and control performance are discussed.
Improvement of thermal radiation characteristic of AC servomotor using Al-CNT composite material
NASA Astrophysics Data System (ADS)
Kikuchi, Y.; Wakiwaka, H.; Yanagihara, M.
2018-02-01
This study deals with a high thermal conductivity material of aluminum-carbon nanotube (CNT) composite with carbon fiber (CF) and the high radiation performance of AC servomotor using a stator made of nanotube composite material. The composite fabrication process was performed by melting a mixture of granular aluminum of less than 200 μm and CNT under conditions of pressed atmosphere at the same time. Two kinds of motors made using aluminum and the composite were evaluated to confirm the effect of thermal conductivity as the motor stator. A test rod of the composite with 14 wt% CF-7 wt% CNT-aluminum indicated the excellent thermal conductivity of 169 W/(mK) in the radial direction and 173 W/(mK) in the lengthwise direction. According to the obtained temperature radiation characteristic of the AC servomotor, the composite stator using CNT decreased the consumption energy to 16% compared to the conventional one. As a result, the highly efficient motor improved the radiation characteristic using the CNT composite stator.
Impact of climate change on occupational exposure to solar radiation.
Grandi, Carlo; Borra, Massimo; Militello, Andrea; Polichetti, Alessandro
2016-01-01
Occupational exposure to solar radiation may induce both acute and long-term effects on skin and eyes. Personal exposure is very difficult to assess accurately, as it depends on environmental, organisational and individual factors. The ongoing climate change interacting with stratospheric ozone dynamics may affect occupational exposure to solar radiation. In addition, tropospheric levels of environmental pollutants interacting with solar radiation may be altered by climate dynamics, so introducing another variable affecting the overall exposure to solar radiation. Given the uncertainties regarding the direction of changes in exposure to solar radiation due to climate change, compliance of outdoor workers with protective measures and a proper health surveillance are crucial. At the same time, education and training, along with the promotion of healthier lifestyles, are of paramount importance.
[Effects of radiation exposure on human body].
Kamiya, Kenji; Sasatani, Megumi
2012-03-01
There are two types of radiation health effect; acute disorder and late on-set disorder. Acute disorder is a deterministic effect that the symptoms appear by exposure above a threshold. Tissues and cells that compose the human body have different radiation sensitivity respectively, and the symptoms appear in order, from highly radiosensitive tissues. The clinical symptoms of acute disorder begin with a decrease in lymphocytes, and then the symptoms appear such as alopecia, skin erythema, hematopoietic damage, gastrointestinal damage, central nervous system damage with increasing radiation dose. Regarding the late on-set disorder, a predominant health effect is the cancer among the symptoms of such as cancer, non-cancer disease and genetic effect. Cancer and genetic effect are recognized as stochastic effects without the threshold. When radiation dose is equal to or more than 100 mSv, it is observed that the cancer risk by radiation exposure increases linearly with an increase in dose. On the other hand, the risk of developing cancer through low-dose radiation exposure, less 100 mSv, has not yet been clarified scientifically. Although uncertainty still remains regarding low level risk estimation, ICRP propound LNT model and conduct radiation protection in accordance with LNT model in the low-dose and low-dose rate radiation from a position of radiation protection. Meanwhile, the mechanism of radiation damage has been gradually clarified. The initial event of radiation-induced diseases is thought to be the damage to genome such as radiation-induced DNA double-strand breaks. Recently, it is clarified that our cells could recognize genome damage and induce the diverse cell response to maintain genome integrity. This phenomenon is called DNA damage response which induces the cell cycle arrest, DNA repair, apoptosis, cell senescence and so on. These responses act in the direction to maintain genome integrity against genome damage, however, the death of large number of cells results in acute disorder, and then DNA mis-repair and mutation is speculated to cause cancer. The extent to which this kind of cellular response could reduce the low-dose radiation risk is a major challenge for future research.
Biodamage via shock waves initiated by irradiation with ions.
Surdutovich, Eugene; Yakubovich, Alexander V; Solov'yov, Andrey V
2013-01-01
Radiation damage following the ionising radiation of tissue has different scenarios and mechanisms depending on the projectiles or radiation modality. We investigate the radiation damage effects due to shock waves produced by ions. We analyse the strength of the shock wave capable of directly producing DNA strand breaks and, depending on the ion's linear energy transfer, estimate the radius from the ion's path, within which DNA damage by the shock wave mechanism is dominant. At much smaller values of linear energy transfer, the shock waves turn out to be instrumental in propagating reactive species formed close to the ion's path to large distances, successfully competing with diffusion.
An ESR study of the UV degradation of FEP
NASA Technical Reports Server (NTRS)
George, G. A.; Hill, D. J. T.; Odonnell, J. H.; Pomery, P. J.; Rasoul, F.
1992-01-01
Spacecraft in low earth orbit are subjected to significant levels of high energy radiation, including ultraviolet (UV) and visible ultraviolet (VUV) wavelengths. The effects of UV radiation are enhanced over those at the surface of the earth, where the only incident wavelengths are greater than 290 nm. In low earth orbit the incident UV wavelengths extend below 290 nm into the VUV region, where the Lyman alpha-emissions of atomic hydrogen occur at 121 nm. In addition to electromagnetic radiation, in low earth orbit polymer materials may also be subjected to atomic oxygen particle radiation, which will result in direct oxidation of the polymer.
NASA Astrophysics Data System (ADS)
Yan, Hao; Wang, Shao-Qiang; Yu, Kai-Liang; Wang, Bin; Yu, Qin; Bohrer, Gil; Billesbach, Dave; Bracho, Rosvel; Rahman, Faiz; Shugart, Herman H.
2017-10-01
Diffuse radiation can increase canopy light use efficiency (LUE). This creates the need to differentiate the effects of direct and diffuse radiation when simulating terrestrial gross primary production (GPP). Here, we present a novel GPP model, the diffuse-fraction-based two-leaf model (DTEC), which includes the leaf response to direct and diffuse radiation, and treats maximum LUE for shaded leaves (ɛmsh defined as a power function of the diffuse fraction (Df)) and sunlit leaves (ɛmsu defined as a constant) separately. An Amazonian rainforest site (KM67) was used to calibrate the model by simulating the linear relationship between monthly canopy LUE and Df. This showed a positive response of forest GPP to atmospheric diffuse radiation, and suggested that diffuse radiation was more limiting than global radiation and water availability for Amazon rainforest GPP on a monthly scale. Further evaluation at 20 independent AmeriFlux sites showed that the DTEC model, when driven by monthly meteorological data and MODIS leaf area index (LAI) products, explained 70% of the variability observed in monthly flux tower GPP. This exceeded the 51% accounted for by the MODIS 17A2 big-leaf GPP product. The DTEC model's explicit accounting for the impacts of diffuse radiation and soil water stress along with its parameterization for C4 and C3 plants was responsible for this difference. The evaluation of DTEC at Amazon rainforest sites demonstrated its potential to capture the unique seasonality of higher GPP during the diffuse radiation-dominated wet season. Our results highlight the importance of diffuse radiation in seasonal GPP simulation.
Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury
Azzam, Edouard I.; Jay-Gerin, Jean-Paul; Pain, Debkumar
2013-01-01
Cellular exposure to ionizing radiation leads to oxidizing events that alter atomic structure through direct interactions of radiation with target macromolecules or via products of water radiolysis. Further, the oxidative damage may spread from the targeted to neighboring, non-targeted bystander cells through redox-modulated intercellular communication mechanisms. To cope with the induced stress and the changes in the redox environment, organisms elicit transient responses at the molecular, cellular and tissue levels to counteract toxic effects of radiation. Metabolic pathways are induced during and shortly after the exposure. Depending on radiation dose, dose-rate and quality, these protective mechanisms may or may not be sufficient to cope with the stress. When the harmful effects exceed those of homeostatic biochemical processes, induced biological changes persist and may be propagated to progeny cells. Physiological levels of reactive oxygen and nitrogen species play critical roles in many cellular functions. In irradiated cells, levels of these reactive species may be increased due to perturbations in oxidative metabolism and chronic inflammatory responses, thereby contributing to the long-term effects of exposure to ionizing radiation on genomic stability. Here, in addition to immediate biological effects of water radiolysis on DNA damage, we also discuss the role of mitochondria in the delayed outcomes of ionization radiation. Defects in mitochondrial functions lead to accelerated aging and numerous pathological conditions. Different types of radiation vary in their linear energy transfer (LET) properties, and we discuss their effects on various aspects of mitochondrial physiology. These include short and long-term in vitro and in vivo effects on mitochondrial DNA, mitochondrial protein import and metabolic and antioxidant enzymes. PMID:22182453
Techniques for the Retrieval of Aerosol Properties Over Land and Ocean Using Multi-angle Imaging
NASA Technical Reports Server (NTRS)
Martonchik, John V.; Diner, David J.; Kahn, Ralph; Ackerman, Thomas P.; Verstraete, Michel M.; Pinty, Bernard; Gordon, Howard R.
1997-01-01
Aerosols are believed to play a direct role in the radiation budget of Earth but their net radiative effect is not well established, particularly on regional scales. Whether aerosols heat or cool a given location depends on their composition and column amount and also on the surface albedo, information that is not routinely available, especially over land.
In radiation biology, a bystander effect occurs when cells not directly exposed to ionizing radiation show increased genomic instability and impaired viability due to the release of signaling molecules by the irradiated cells in their vicinity. Christophe Redon, Ph.D., and colleagues in CCR’s Laboratory of Molecular Pharmacology, decided to ask whether a tumor itself could
Seeing tobacco mosaic virus through direct electron detectors
Fromm, Simon A.; Bharat, Tanmay A.M.; Jakobi, Arjen J.; Hagen, Wim J.H.; Sachse, Carsten
2015-01-01
With the introduction of direct electron detectors (DED) to the field of electron cryo-microscopy, a wave of atomic-resolution structures has become available. As the new detectors still require comparative characterization, we have used tobacco mosaic virus (TMV) as a test specimen to study the quality of 3D image reconstructions from data recorded on the two direct electron detector cameras, K2 Summit and Falcon II. Using DED movie frames, we explored related image-processing aspects and compared the performance of micrograph-based and segment-based motion correction approaches. In addition, we investigated the effect of dose deposition on the atomic-resolution structure of TMV and show that radiation damage affects negative carboxyl chains first in a side-chain specific manner. Finally, using 450,000 asymmetric units and limiting the effects of radiation damage, we determined a high-resolution cryo-EM map at 3.35 Å resolution. Here, we provide a comparative case study of highly ordered TMV recorded on different direct electron detectors to establish recording and processing conditions that enable structure determination up to 3.2 Å in resolution using cryo-EM. PMID:25528571
The Impact of Radiation Changes on the Terrestrial Carbon Sink over the Post Pinatubo Period
NASA Astrophysics Data System (ADS)
Sitch, S.; Mercado, L. M.; Bellouin, N.; Boucher, O.; Huntingford, C.; Cox, P. M.
2008-12-01
The amount of solar radiation reaching the earth surface is one of the major drivers of plant photosynthesis and therefore changes in radiation are likely to indirectly have an effect on the terrestrial carbon cycle. For example, changes in surface radiation that lead to increasing diffuse surface irradiance are reported to enhance plant photosynthesis (Gu et al., 2003, Niyogi et al., 2004, Oliveira et al., 2007, Roderick et al., 2001). Solar radiation reaching the land surface has changed over the industrial era due to aerosols emitted from volcanoes and various anthropogenic sources (Kvalevag and Myhre, 2007). Such changes in total surface radiation are accompanied by changes in direct and diffuse surface solar radiation. Recent major volcanic events include the eruptions of el Chichón in 1986 and Mount Pinatubo in 1991. In this study we estimate the impact of changes in surface radiation on photosynthetic carbon uptake during the Post Pinatubo period. We use an offline version of the Hadley Centre land surface scheme (Mercado et al., 2007) modified to account for variations in direct and diffuse radiation on sunlit and shaded canopy photosynthesis. We use meteorological forcing from the Climate Research Unit Data set. Additionally short wave and photosynthetic active radiation are reconstructed from the Hadley centre climate model, which accounts for the scattering and absorption of light by tropospheric and stratospheric aerosols. We describe the development of the land carbon cycle through the Pinatubo event and diagnose the impact of changes in diffuse radiation on the atmospheric [CO2] growth-rate
NASA Astrophysics Data System (ADS)
Diaz-Torres, L. A.; Meza, O.; Solis, D.; Salas, P.; De la Rosa, E.
2011-06-01
Wide band gap Yb 3+ and Er 3+ codoped ZrO 2 nanocrystals have been synthesized by a modified sol-gel method. Under 967 nm excitation strong green and red upconversion emission is observed for several Er 3+ to Yb 3+ ions concentration ratios. A simple microscopic rate equation model is used to study the effects of non-radiative direct Yb 3+ to Er 3+ energy transfer processes on the visible and near infrared fluorescence decay trends of both Er 3+ and Yb 3+ ions. The microscopic rate equation model takes into account the crystalline phase as well as the size of nanocrystals. Nanocrystals phase and size were estimated from XRD patterns. The rate equation model succeeds to fit simultaneously all visible and near infrared fluorescence decay profiles. The dipole-dipole interaction parameters that drive the non-radiative energy transfer processes depend on doping concentration due to crystallite phase changes. In addition the non-radiative relaxation rate ( 4I11/2→ 4I13/2) is found to be greater than that estimated by the Judd-Ofelt parameters due to the action of surface impurities. Results suggest that non-radiative direct Yb 3+ to Er 3+ energy transfer processes in ZrO 2:Yb,Er are extremely efficient.
Wakeford, Richard
2009-06-01
Many individuals are, or have been, exposed to ionising radiation in the course of their work and the epidemiological study of occupationally irradiated groups offers an important opportunity to complement the estimates of risks to health resulting from exposure to radiation that are obtained from other populations, such as the Japanese survivors of the atomic bombings of Hiroshima and Nagasaki in 1945. Moreover, workplace exposure to radiation usually involves irradiation conditions that are of direct relevance to the principal concern of radiological protection: protracted exposure to low level radiation. Further, some workers have been exposed to radioactive material that has been inadvertently taken into the body, and the study of these groups leads to risk estimates derived directly from the experience of those irradiated by these 'internal emitters', intakes of alpha-particle-emitters being of particular interest. Workforces that have been the subject of epidemiological study include medical staff, aircrews, radium dial luminisers, underground hard-rock miners, Chernobyl clean-up workers, nuclear weapons test participants and nuclear industry workers. The first solid epidemiological evidence of the stochastic effects of irradiation came from a study of occupational exposure to medical x-rays that was reported in 1944, which demonstrated a large excess risk of leukaemia among US radiologists; but the general lack of dose records for early medical staff who tended to experience the highest exposures hampers the derivation of risks per unit dose received by medical workers. The instrument dial luminisers who inadvertently ingested large amounts of radium-based paint and underground hard-rock miners who inhaled large quantities of radon and its decay products suffered markedly raised excess risks of, respectively, bone and lung cancers; the miner studies have provided standard risk estimates for radon-induced lung cancer. The large numbers of nuclear industry workers around the world present a possibility of deriving risk coefficients of direct relevance to radiological protection, and the recently published study of workers from 15 countries illustrates what can be achieved by international collaboration. However, it would appear that there are some problems with this study that require attention before reliance can be placed upon the results. Early workers from the Mayak plutonium production facility in Russia were heavily exposed to external sources of penetrating radiation and to plutonium, and appreciable effort has been expended in obtaining dependable risk estimates from this scientifically valuable group of workers. Those occupationally exposed to low levels of radiation also present an opportunity of studying possible somatic health effects other than cancer, such as heart disease and eye cataracts, that are the subject of much discussion at present. Overall, studies of exposure to ionising radiation in the workplace provide a valuable support to studies of those groups exposed under other circumstances, and in some instances (such as exposure to plutonium) effectively offer the only direct source of epidemiological evidence on risks.
NASA Technical Reports Server (NTRS)
Hansell, R. A.; Tsay, S. C.; Ji, Q.; Hsu, N. C.; Jeong, M. J.; Wang, S. H.; Reid, J. S.; Liou, K. N.; Ou, S. C.
2010-01-01
In September 2006, NASA Goddard s mobile ground-based laboratories were deployed to Sal Island in Cape Verde (16.73degN, 22.93degW) to support the NASA African Monsoon Multidisciplinary Analysis (NAMMA) field study. The Atmospheric Emitted Radiance Interferometer (AERI), a key instrument for spectrally characterizing the thermal IR, was used to retrieve the dust IR aerosol optical depths (AOTs) in order to examine the diurnal variability of airborne dust with emphasis on three separate dust events. AERI retrievals of dust AOT are compared with those from the coincident/collocated multifilter rotating shadow-band radiometer (MFRSR), micropulse lidar (MPL), and NASA Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO) sensors. The retrieved AOTs are then inputted into the Fu-Liou 1D radiative transfer model to evaluate local instantaneous direct longwave radiative effects (DRE(sub LW)) of dust at the surface in cloud-free atmospheres and its sensitivity to dust microphysical parameters. The top-of-atmosphere DRE(sub LW) and longwave heating rate profiles are also evaluated. Instantaneous surface DRE(sub LW) ranges from 2 to 10 W/sq m and exhibits a strong linear dependence with dust AOT yielding a DRE(sub LW) of 16 W/sq m per unit dust AOT. The DRE(sub LW) is estimated to be approx.42% of the diurnally averaged direct shortwave radiative effect at the surface but of opposite sign, partly compensating for the shortwave losses. Certainly nonnegligible, the authors conclude that DRE(sub LW) can significantly impact the atmospheric energetics, representing an important component in the study of regional climate variation.
Kovalchuk, Anna; Mychasiuk, Richelle; Muhammad, Arif; Hossain, Shakhawat; Ilnytskyy, Yaroslav; Ghose, Abhijit; Kirkby, Charles; Ghasroddashti, Esmaeel; Kolb, Bryan; Kovalchuk, Olga
2016-01-01
Irradiated cells can signal damage and distress to both close and distant neighbors that have not been directly exposed to the radiation (naïve bystanders). While studies have shown that such bystander effects occur in the shielded brain of animals upon body irradiation, their mechanism remains unexplored. Observed effects may be caused by some blood-borne factors; however they may also be explained, at least in part, by very small direct doses received by the brain that result from scatter or leakage. In order to establish the roles of low doses of scatter irradiation in the brain response, we developed a new model for scatter irradiation analysis whereby one rat was irradiated directly at the liver and the second rat was placed adjacent to the first and received a scatter dose to its body and brain. This work focuses specifically on the response of the latter rat brain to the low scatter irradiation dose. Here, we provide the first experimental evidence that very low, clinically relevant doses of scatter irradiation alter gene expression, induce changes in dendritic morphology, and lead to behavioral deficits in exposed animals. The results showed that exposure to radiation doses as low as 0.115 cGy caused changes in gene expression and reduced spine density, dendritic complexity, and dendritic length in the prefrontal cortex tissues of females, but not males. In the hippocampus, radiation altered neuroanatomical organization in males, but not in females. Moreover, low dose radiation caused behavioral deficits in the exposed animals. This is the first study to show that low dose scatter irradiation influences the brain and behavior in a sex-specific way. PMID:27375442
Schlumberger, Martin; Le Guen, Bernard
2012-01-01
Following the Chernobyl accident, enormous amounts of radioisotopes were released in the atmosphere and have contaminated surrounding populations in the absence of rapid protective countermeasures. The highest radiation doses were delivered to the thyroid gland, and the only direct consequence of radiation exposure observed among contaminated population is the increased incidence of thyroid cancers among subjects who were children in 1986 and who lived at that time in Belarus, Ukraine or Russia. © 2012 médecine/sciences – Inserm / SRMS.
A Ten-Year Global Record of Absorbing Aerosols Above Clouds from OMI's Near-UV Observations
NASA Technical Reports Server (NTRS)
Jethva, Hiren; Torres, Omar; Ahn, Changwoo
2016-01-01
Aerosol-cloud interaction continues to be one of the leading uncertain components of climate models, primarily due to the lack of an adequate knowledge of the complex microphysical and radiative processes associated with the aerosol-cloud system. The situations when aerosols and clouds are found in the same atmospheric column, for instance, when light-absorbing aerosols such as biomass burning generated carbonaceous particles or wind-blown dust overlay low-level cloud decks, are commonly found over several regional of the world. Contrary to the cloud-free scenario over dark surface, for which aerosols are known to produce a net cooling effect (negative radiative forcing) on climate, the overlapping situation of absorbing aerosols over cloud can potentially exert a significant level of atmospheric absorption and produces a positive radiative forcing at top-of-atmosphere. The magnitude of direct radiative effects of aerosols above cloud depends directly on the aerosol loading, microphysical-optical properties of the aerosol layer and the underlying cloud deck, and geometric cloud fraction. We help in addressing this problem by introducing a novel product of optical depth of absorbing aerosols above clouds retrieved from near-UV observations made by the Ozone Monitoring Instrument (OMI) on board NASA's Aura platform. The presence of absorbing aerosols above cloud reduces the upwelling radiation reflected by cloud and produces a strong 'color ratio' effect in the near-UV region, which can be unambiguously detected in the OMI measurements. Physically based on this effect, the OMACA algorithm retrieves the optical depths of aerosols and clouds simultaneously under a prescribed state of atmosphere. The algorithm architecture and results from a ten-year global record including global climatology of frequency of occurrence and above-cloud aerosol optical depth, and a discussion on related future field campaigns are presented.
Radiation risk estimation: Modelling approaches for “targeted” and “non-targeted” effects
NASA Astrophysics Data System (ADS)
Ballarini, Francesca; Alloni, Daniele; Facoetti, Angelica; Mairani, Andrea; Nano, Rosanna; Ottolenghi, Andrea
The estimation of the risks from low doses of ionizing radiation - including heavy ions - is still a debated question. In particular, the action of heavy ions on biological targets needs further investigation. In this framework, we present a mechanistic model and a Monte Carlo simulation code for the induction of different types of chromosome aberrations. The model, previously validated for gamma rays and light ions, has recently started to be extended to heavy ions such as Iron and Carbon, which are of interest both for space radiation protection and for hadrontherapy. Preliminary results were found to be in agreement with experimental dose-response curves for aberration yields observed following heavy-ion irradiation of human lymphocytes treated with the Premature Chromosome Condensation technique. During the last 10 years, the "Linear No Threshold" hypothesis has been challenged by a large number of observations on the so-called "non-targeted effects" including bystander effect, which consists of the induction of cytogenetic damage in cells not directly traversed by radiation, most likely as a response to molecular messengers released by directly irradiated cells. Although it is now clear that cellular communication plays a fundamental role, our knowledge on the mechanisms underlying bystander effects is still poor, and would largely benefit from further investigations including theoretical models and simulation codes. In the present paper we will review different modelling approaches, including one that is being developed at the University of Pavia, focusing on the assumptions adopted by the various authors and on their implications in terms of low-dose radiation risk, as well as on the identification of "critical" parameters that can modulate the model outcomes.
Non local-thermodynamical-equilibrium effects in the simulation of laser-produced plasmas
NASA Astrophysics Data System (ADS)
Klapisch, M.; Bar-Shalom, A.; Oreg, J.; Colombant, D.
1998-05-01
Local thermodynamic equilibrium (LTE) breaks down in directly or indirectly driven laser plasmas because of sharp gradients, energy deposition, etc. For modeling non-LTE effects in hydrodynamical simulations, Busquet's model [Phys. Fluids B 5, 4191 (1993)] is very convenient and efficient. It uses off-line generated LTE opacities and equation of states via an effective, radiation-dependent ionization temperature Tz. An overview of the model is given. The results are compared with an elaborate collisional radiative model based on superconfigurations. The agreements for average charge Z* and opacities are surprisingly good, even more so when the plasma is immersed in a radiation field. Some remaining discrepancy at low density is attributed to dielectronic recombination. Improvement appears possible, especially for emissivities, because the concept of ionization temperature seems to be validated.
Coordinated weather balloon solar radiation measurements during a solar eclipse
2016-01-01
Solar eclipses provide a rapidly changing solar radiation environment. These changes can be studied using simple photodiode sensors, if the radiation reaching the sensors is unaffected by cloud. Transporting the sensors aloft using standard meteorological instrument packages modified to carry extra sensors, provides one promising but hitherto unexploited possibility for making solar eclipse radiation measurements. For the 20 March 2015 solar eclipse, a coordinated campaign of balloon-carried solar radiation measurements was undertaken from Reading (51.44°N, 0.94°W), Lerwick (60.15°N, 1.13°W) and Reykjavik (64.13°N, 21.90°W), straddling the path of the eclipse. The balloons reached sufficient altitude at the eclipse time for eclipse-induced variations in solar radiation and solar limb darkening to be measured above cloud. Because the sensor platforms were free to swing, techniques have been evaluated to correct the measurements for their changing orientation. In the swing-averaged technique, the mean value across a set of swings was used to approximate the radiation falling on a horizontal surface; in the swing-maximum technique, the direct beam was estimated by assuming that the maximum solar radiation during a swing occurs when the photodiode sensing surface becomes normal to the direction of the solar beam. Both approaches, essentially independent, give values that agree with theoretical expectations for the eclipse-induced radiation changes. This article is part of the themed issue ‘Atmospheric effects of solar eclipses stimulated by the 2015 UK eclipse’. PMID:27550757
Coordinated weather balloon solar radiation measurements during a solar eclipse.
Harrison, R G; Marlton, G J; Williams, P D; Nicoll, K A
2016-09-28
Solar eclipses provide a rapidly changing solar radiation environment. These changes can be studied using simple photodiode sensors, if the radiation reaching the sensors is unaffected by cloud. Transporting the sensors aloft using standard meteorological instrument packages modified to carry extra sensors, provides one promising but hitherto unexploited possibility for making solar eclipse radiation measurements. For the 20 March 2015 solar eclipse, a coordinated campaign of balloon-carried solar radiation measurements was undertaken from Reading (51.44°N, 0.94°W), Lerwick (60.15°N, 1.13°W) and Reykjavik (64.13°N, 21.90°W), straddling the path of the eclipse. The balloons reached sufficient altitude at the eclipse time for eclipse-induced variations in solar radiation and solar limb darkening to be measured above cloud. Because the sensor platforms were free to swing, techniques have been evaluated to correct the measurements for their changing orientation. In the swing-averaged technique, the mean value across a set of swings was used to approximate the radiation falling on a horizontal surface; in the swing-maximum technique, the direct beam was estimated by assuming that the maximum solar radiation during a swing occurs when the photodiode sensing surface becomes normal to the direction of the solar beam. Both approaches, essentially independent, give values that agree with theoretical expectations for the eclipse-induced radiation changes.This article is part of the themed issue 'Atmospheric effects of solar eclipses stimulated by the 2015 UK eclipse'. © 2016 The Authors.
Eye safety related to near infrared radiation exposure to biometric devices.
Kourkoumelis, Nikolaos; Tzaphlidou, Margaret
2011-03-01
Biometrics has become an emerging field of technology due to its intrinsic security features concerning the identification of individuals by means of measurable biological characteristics. Two of the most promising biometric modalities are iris and retina recognition, which primarily use nonionizing radiation in the infrared region. Illumination of the eye is achieved by infrared light emitting diodes (LEDs). Even if few LED sources are capable of causing direct eye damage as they emit incoherent light, there is a growing concern about the possible use of LED arrays that might pose a potential threat. Exposure to intense coherent infrared radiation has been proven to have significant effects on living tissues. The purpose of this study is to explore the biological effects arising from exposing the eye to near infrared radiation with reference to international legislation.
The direct effect of aerosols on solar radiation over the broader Mediterranean basin
NASA Astrophysics Data System (ADS)
Papadimas, C. D.; Hatzianastassiou, N.; Matsoukas, C.; Kanakidou, M.; Mihalopoulos, N.; Vardavas, I.
2011-11-01
For the first time, the direct radiative effect (DRE) of aerosols on solar radiation is computed over the entire Mediterranean basin, one of the most climatically sensitive world regions, by using a deterministic spectral radiation transfer model (RTM). The DRE effects on the outgoing shortwave radiation at the top of atmosphere (TOA), DRETOA, on the absorption of solar radiation in the atmospheric column, DREatm, and on the downward and absorbed surface solar radiation (SSR), DREsurf and DREnetsurf, respectively, are computed separately. The model uses input data for the period 2000-2007 for various surface and atmospheric parameters, taken from satellite (International Satellite Cloud Climatology Project, ISCCP-D2), Global Reanalysis projects (National Centers for Environmental Prediction - National Center for Atmospheric Research, NCEP/NCAR), and other global databases. The spectral aerosol optical properties (aerosol optical depth, AOD, asymmetry parameter, gaer and single scattering albedo, ωaer), are taken from the MODerate resolution Imaging Spectroradiometer (MODIS) of NASA (National Aeronautics and Space Administration) and they are Supplemented by the Global Aerosol Data Set (GADS). The model SSR fluxes have been successfully validated against measurements from 80 surface stations of the Global Energy Balance Archive (GEBA) covering the period 2000-2007. A planetary cooling is found above the Mediterranean on an annual basis (regional mean DRETOA = -2.4 Wm-2). Though planetary cooling is found over most of the region, up to -7 Wm-2, large positive DRETOA values (up to +25 Wm-2) are found over North Africa, indicating a strong planetary warming, as well as over the Alps (+0.5 Wm-2). Aerosols are found to increase the absorption of solar radiation in the atmospheric column over the region (DREatm = +11.1 Wm-2) and to decrease SSR (DREsurf = -16.5 Wm-2 and DREnetsurf -13.5 Wm-2) inducing thus significant atmospheric warming and surface radiative cooling. The calculated seasonal and monthly DREs are even larger, reaching -25.4 Wm-2 (for DREsurf). Sensitivity tests show that regional DREs are most sensitive to ωaer and secondarily to AOD, showing a quasi-linear dependence to these aerosol parameters.
Lee, Kyu-Tae; Yao, Yuan; He, Junwen; Fisher, Brent; Sheng, Xing; Lumb, Matthew; Xu, Lu; Anderson, Mikayla A.; Scheiman, David; Han, Seungyong; Kang, Yongseon; Gumus, Abdurrahman; Bahabry, Rabab R.; Lee, Jung Woo; Paik, Ungyu; Bronstein, Noah D.; Alivisatos, A. Paul; Meitl, Matthew; Burroughs, Scott; Hussain, Muhammad Mustafa; Lee, Jeong Chul; Nuzzo, Ralph G.; Rogers, John A.
2016-01-01
Emerging classes of concentrator photovoltaic (CPV) modules reach efficiencies that are far greater than those of even the highest performance flat-plate PV technologies, with architectures that have the potential to provide the lowest cost of energy in locations with high direct normal irradiance (DNI). A disadvantage is their inability to effectively use diffuse sunlight, thereby constraining widespread geographic deployment and limiting performance even under the most favorable DNI conditions. This study introduces a module design that integrates capabilities in flat-plate PV directly with the most sophisticated CPV technologies, for capture of both direct and diffuse sunlight, thereby achieving efficiency in PV conversion of the global solar radiation. Specific examples of this scheme exploit commodity silicon (Si) cells integrated with two different CPV module designs, where they capture light that is not efficiently directed by the concentrator optics onto large-scale arrays of miniature multijunction (MJ) solar cells that use advanced III–V semiconductor technologies. In this CPV+ scheme (“+” denotes the addition of diffuse collector), the Si and MJ cells operate independently on indirect and direct solar radiation, respectively. On-sun experimental studies of CPV+ modules at latitudes of 35.9886° N (Durham, NC), 40.1125° N (Bondville, IL), and 38.9072° N (Washington, DC) show improvements in absolute module efficiencies of between 1.02% and 8.45% over values obtained using otherwise similar CPV modules, depending on weather conditions. These concepts have the potential to expand the geographic reach and improve the cost-effectiveness of the highest efficiency forms of PV power generation. PMID:27930331
Lee, Kyu-Tae; Yao, Yuan; He, Junwen; ...
2016-12-05
Emerging classes ofconcentrator photovoltaic (CPV) modules reach efficiencies that are far greater than those of even the highest performance flat-plate PV technologies, with architectures that have the potential to provide the lowest cost of energy in locations with high direct normal irradiance (DNI). A disadvantage is their inability to effectively use diffuse sunlight, thereby constraining widespread geographic deployment and limiting performance even under the most favorable DNI conditions. This study introduces a module design that integrates capabilities in flat-plate PV directly with the most sophisticated CPV technologies, for capture of both direct and diffuse sunlight, thereby achieving efficiency in PVmore » conversion of the global solar radiation. Specific examples of this scheme exploit commodity silicon (Si) cells integrated with two different CPV module designs, where they capture light that is not efficiently directed by the concentrator optics onto large-scale arrays of miniature multijunction (MJ) solar cells that use advanced III-V semiconductor technologies. In this CPV + scheme ("+" denotes the addition of diffuse collector), the Si and MJ cells operate independently on indirect and direct solar radiation, respectively. On-sun experimental studies of CPV + modules at latitudes of 35.9886° N (Durham, NC), 40.1125° N (Bondville, IL), and 38.9072° N (Washington, DC) show improvements in absolute module efficiencies of between 1.02% and 8.45% over values obtained using otherwise similar CPV modules, depending on weather conditions. These concepts have the potential to expand the geographic reach and improve the cost-effectiveness of the highest efficiency forms of PV power generation.« less
NASA Astrophysics Data System (ADS)
Lee, Kyu-Tae; Yao, Yuan; He, Junwen; Fisher, Brent; Sheng, Xing; Lumb, Matthew; Xu, Lu; Anderson, Mikayla A.; Scheiman, David; Han, Seungyong; Kang, Yongseon; Gumus, Abdurrahman; Bahabry, Rabab R.; Lee, Jung Woo; Paik, Ungyu; Bronstein, Noah D.; Alivisatos, A. Paul; Meitl, Matthew; Burroughs, Scott; Mustafa Hussain, Muhammad; Lee, Jeong Chul; Nuzzo, Ralph G.; Rogers, John A.
2016-12-01
Emerging classes of concentrator photovoltaic (CPV) modules reach efficiencies that are far greater than those of even the highest performance flat-plate PV technologies, with architectures that have the potential to provide the lowest cost of energy in locations with high direct normal irradiance (DNI). A disadvantage is their inability to effectively use diffuse sunlight, thereby constraining widespread geographic deployment and limiting performance even under the most favorable DNI conditions. This study introduces a module design that integrates capabilities in flat-plate PV directly with the most sophisticated CPV technologies, for capture of both direct and diffuse sunlight, thereby achieving efficiency in PV conversion of the global solar radiation. Specific examples of this scheme exploit commodity silicon (Si) cells integrated with two different CPV module designs, where they capture light that is not efficiently directed by the concentrator optics onto large-scale arrays of miniature multijunction (MJ) solar cells that use advanced III-V semiconductor technologies. In this CPV+ scheme (“+” denotes the addition of diffuse collector), the Si and MJ cells operate independently on indirect and direct solar radiation, respectively. On-sun experimental studies of CPV+ modules at latitudes of 35.9886° N (Durham, NC), 40.1125° N (Bondville, IL), and 38.9072° N (Washington, DC) show improvements in absolute module efficiencies of between 1.02% and 8.45% over values obtained using otherwise similar CPV modules, depending on weather conditions. These concepts have the potential to expand the geographic reach and improve the cost-effectiveness of the highest efficiency forms of PV power generation.
Lee, Kyu-Tae; Yao, Yuan; He, Junwen; Fisher, Brent; Sheng, Xing; Lumb, Matthew; Xu, Lu; Anderson, Mikayla A; Scheiman, David; Han, Seungyong; Kang, Yongseon; Gumus, Abdurrahman; Bahabry, Rabab R; Lee, Jung Woo; Paik, Ungyu; Bronstein, Noah D; Alivisatos, A Paul; Meitl, Matthew; Burroughs, Scott; Hussain, Muhammad Mustafa; Lee, Jeong Chul; Nuzzo, Ralph G; Rogers, John A
2016-12-20
Emerging classes of concentrator photovoltaic (CPV) modules reach efficiencies that are far greater than those of even the highest performance flat-plate PV technologies, with architectures that have the potential to provide the lowest cost of energy in locations with high direct normal irradiance (DNI). A disadvantage is their inability to effectively use diffuse sunlight, thereby constraining widespread geographic deployment and limiting performance even under the most favorable DNI conditions. This study introduces a module design that integrates capabilities in flat-plate PV directly with the most sophisticated CPV technologies, for capture of both direct and diffuse sunlight, thereby achieving efficiency in PV conversion of the global solar radiation. Specific examples of this scheme exploit commodity silicon (Si) cells integrated with two different CPV module designs, where they capture light that is not efficiently directed by the concentrator optics onto large-scale arrays of miniature multijunction (MJ) solar cells that use advanced III-V semiconductor technologies. In this CPV + scheme ("+" denotes the addition of diffuse collector), the Si and MJ cells operate independently on indirect and direct solar radiation, respectively. On-sun experimental studies of CPV + modules at latitudes of 35.9886° N (Durham, NC), 40.1125° N (Bondville, IL), and 38.9072° N (Washington, DC) show improvements in absolute module efficiencies of between 1.02% and 8.45% over values obtained using otherwise similar CPV modules, depending on weather conditions. These concepts have the potential to expand the geographic reach and improve the cost-effectiveness of the highest efficiency forms of PV power generation.
NASA Astrophysics Data System (ADS)
Feng, N.
2015-12-01
The influences of anthropogenic aerosols have been suggested as an important reason for climate changes over Southeast Asia (SE Asia, 10°S~20°N and 90°E~135°E). Accurate observations and modelling of aerosols effects on the weather and climate patterns is crucial for a better understanding and mitigation of anthropogenic climate change. This study uses NASA satellite observations along with online-coupled Weather Research and Forecasting model with Chemistry (WRF-Chem) to evaluate aerosols impacts on climate over SE Asia. We assess the direct and semi-direct radiative effects of smoke particles over this region during September, 2009 when a significant El Niño event caused the highest biomass burning activity during the last 15 years. Quantification efforts are made to assess how changes of radiative and non radiative parameters (sensible and latent heat) due to smoke aerosols would affect regional climate process such as precipitations, clouds and planetary boundary layer process. Comparison of model simulations for the current land cover conditions against surface meteorological observations and satellite observations of precipitations and cloudiness show satisfactory performance of the model over our study area. In order to quantitatively validate the model results, several experiments will be performed to test the aerosols radiative feedback under different radiation schemes and with/without considering aerosol effects explicitly in the model. Relevant ground-based data (e.g. AERONET), along with aerosol vertical profile data from CALIPSO, will also be applied.
Integrative Analysis of Desert Dust Size and Abundance Suggests Less Dust Climate Cooling
NASA Technical Reports Server (NTRS)
Kok, Jasper F.; Ridley, David A.; Zhou, Qing; Miller, Ron L.; Zhao, Chun; Heald, Colette L.; Ward, Daniel S.; Albani, Samuel; Haustein, Karsten
2017-01-01
Desert dust aerosols affect Earths global energy balance through interactions with radiation, clouds, and ecosystems. But the magnitudes of these effects are so uncertain that it remains unclear whether atmospheric dust has a net warming or cooling effect on global climate. Consequently, it is still uncertain whether large changes in atmospheric dust loading over the past century have slowed or accelerated anthropogenic climate change, and the climate impact of possible future alterations in dust loading is similarly disputed. Here we use an integrative analysis of dust aerosol sizes and abundance to constrain the climatic impact of dust through direct interactions with radiation. Using a combination of observational, experimental, and model data, we find that atmospheric dust is substantially coarser than represented in current climate models. Since coarse dust warms global climate, the dust direct radiative effect (DRE) is likely less cooling than the 0.4 W m superscript 2 estimated by models in a current ensemble. We constrain the dust DRE to -0.20 (-0.48 to +0.20) W m superscript 2, which suggests that the dust DRE produces only about half the cooling that current models estimate, and raises the possibility that dust DRE is actually net warming the planet.
Race, C P; Mason, D R; Sutton, A P
2009-03-18
Using time-dependent tight-binding simulations of radiation damage cascades in a model metal we directly investigate the nature of the excitations of a system of quantum mechanical electrons in response to the motion of a set of classical ions. We furthermore investigate the effect of these excitations on the attractive electronic forces between the ions. We find that the electronic excitations are well described by a Fermi-Dirac distribution at some elevated temperature, even in the absence of the direct electron-electron interactions that would be required in order to thermalize a non-equilibrium distribution. We explain this result in terms of the spectrum of characteristic frequencies of the ionic motion. Decomposing the electronic force into four well-defined components within the basis of instantaneous electronic eigenstates, we find that the effect of accumulated excitations in weakening the interionic bonds is mostly (95%) accounted for by a thermal model for the electronic excitations. This result justifies the use of the simplifying assumption of a thermalized electron system in simulations of radiation damage with an electronic temperature dependence and in the development of temperature-dependent classical potentials.
NASA Technical Reports Server (NTRS)
Zhang, Z.; Meyer, K.; Platnick, S.; Oreopoulos, L.; Lee, D.; Yu, H.
2013-01-01
This paper describes an efficient and unique method for computing the shortwave direct radiative effect (DRE) of aerosol residing above low-level liquid-phase clouds using CALIOP and MODIS data. It accounts for the overlapping of aerosol and cloud rigorously by utilizing the joint histogram of cloud optical depth and cloud top pressure. Effects of sub-grid scale cloud and aerosol variations on DRE are accounted for. It is computationally efficient through using grid-level cloud and aerosol statistics, instead of pixel-level products, and a pre-computed look-up table in radiative transfer calculations. We verified that for smoke over the southeast Atlantic Ocean the method yields a seasonal mean instantaneous shortwave DRE that generally agrees with more rigorous pixel-level computation within 4%. We have also computed the annual mean instantaneous shortwave DRE of light-absorbing aerosols (i.e., smoke and polluted dust) over global ocean based on 4 yr of CALIOP and MODIS data. We found that the variability of the annual mean shortwave DRE of above-cloud light-absorbing aerosol is mainly driven by the optical depth of the underlying clouds.
NASA Technical Reports Server (NTRS)
Zhang, Z.; Meyer, K.; Platnick, S.; Oreopoulos, L.; Lee, D.; Yu, H.
2014-01-01
This paper describes an efficient and unique method for computing the shortwave direct radiative effect (DRE) of aerosol residing above low-level liquid-phase clouds using CALIOP and MODIS data. It accounts for the overlapping of aerosol and cloud rigorously by utilizing the joint histogram of cloud optical depth and cloud top pressure. Effects of sub-grid scale cloud and aerosol variations on DRE are accounted for. It is computationally efficient through using grid-level cloud and aerosol statistics, instead of pixel-level products, and a pre-computed look-up table in radiative transfer calculations. We verified that for smoke over the southeast Atlantic Ocean the method yields a seasonal mean instantaneous shortwave DRE that generally agrees with more rigorous pixel-level computation within 4. We have also computed the annual mean instantaneous shortwave DRE of light-absorbing aerosols (i.e., smoke and polluted dust) over global ocean based on 4 yr of CALIOP and MODIS data. We found that the variability of the annual mean shortwave DRE of above-cloud light-absorbing aerosol is mainly driven by the optical depth of the underlying clouds.
Radiation interactions with biological systems.
Islam, Muhammad Torequl
2017-05-01
The use of radiation, especially ionizing radiation (IR), is currently attracting great attention in the field of medical sciences. However, it should be mentioned that IR has both beneficial and harmful effects in biological systems. This review aims to focus on IR-mediated physiological events in a mechanistic way. Evidence from the databases, mainly from PUBMED and SCIENCE DIRECT were considered. IR directly and/or with their lyses products (indirect) causes oxidative stresses to biological systems. These activities may be localized and systematic. Otherwise, IR-induced non-/multi-targeted effects are also evident. IR in diagnosis and cancer radiotherapy is well-known. Reactive species produced by IR are not only beneficial, but also can exert harmful effects in a biological system such as aging, genetic instability and mutagenicity, membrane lysis and cell death, alteration of enzymatic activity and metabolic events, mitochondrial dysfunction, and even cancer. Additionally, DNA adducts formation, after IR-induced DNA breakage, is a cause of blockage of DNA repair capability with an increase in cellular radiosensitivity. These may allow cellular ruin even at low IR levels. Dependent on the dose, duration of action and quality, IR plays diverse roles in biological systems.
Quantitative impact of aerosols on numerical weather prediction. Part I: Direct radiative forcing
NASA Astrophysics Data System (ADS)
Marquis, J. W.; Zhang, J.; Reid, J. S.; Benedetti, A.; Christensen, M.
2017-12-01
While the effects of aerosols on climate have been extensively studied over the past two decades, the impacts of aerosols on operational weather forecasts have not been carefully quantified. Despite this lack of quantification, aerosol plumes can impact weather forecasts directly by reducing surface reaching solar radiation and indirectly through affecting remotely sensed data that are used for weather forecasts. In part I of this study, the direct impact of smoke aerosol plumes on surface temperature forecasts are quantified using a smoke aerosol event affecting the United States Upper-Midwest in 2015. NCEP, ECMWF and UKMO model forecast surface temperature uncertainties are studied with respect to aerosol loading. Smoke aerosol direct cooling efficiencies are derived and the potential of including aerosol particles in operational forecasts is discussed, with the consideration of aerosol trends, especially over regions with heavy aerosol loading.
Koberg, Miri; Cohen, Moshe; Ben-Amotz, Ami; Gedanken, Aharon
2011-03-01
This work offers an optimized method for the direct conversion of harvested Nannochloropsis algae into bio-diesel using two novel techniques. The first is a unique bio-technology-based environmental system utilizing flue gas from coal burning power stations for microalgae cultivation. This method reduces considerably the cost of algae production. The second technique is the direct transesterification (a one-stage method) of the Nannochloropsis biomass to bio-diesel production using microwave and ultrasound radiation with the aid of a SrO catalyst. These two techniques were tested and compared to identify the most effective bio-diesel production method. Based on our results, it is concluded that the microwave oven method appears to be the most simple and efficient method for the one-stage direct transesterification of the as-harvested Nannochloropsis algae. Copyright © 2010 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Iles, R. H. A.; Taylor, G. C.; Jones, J. B. L.
January 2000 saw the start of a collaborative study involving the Mullard Space Science Laboratory, Virgin Atlantic Airways, the Civil Aviation Authority and the National Physical Laboratory in a program to investigate the cosmic radiation exposure to aircrew. The study has been undertaken in view of EU Directive 96/291 (May 2000) which requires the assessment of the level of radiation exposure to aircrew. The project's aims include validation of radiation dose models and evaluation of space weather effects on atmospheric cosmic radiation levels, in particular those effects not accounted for by the models. Ground level measurements are often used as a proxy for variations in cosmic radiation dose levels at aircraft altitudes, especially during Forbush Decreases (FDs) and Solar Energetic Particle (SEP) events. Is this estimation realistic and does the ground level data accurately represent what is happening at altitude? We have investigated the effect of a FD during a flight from Hong Kong to London Heathrow on the 15th July 2000 and compared count rate and dose measurements with simultaneous variations measured at ground level. We have also compared the results with model outputs.
SW radiative effect of aerosol in GRAPES_GFS
NASA Astrophysics Data System (ADS)
Chen, Qiying
2017-04-01
The aerosol particles can scatter and absorb solar radiation, and so change the shortwave radiation absorbed by the atmosphere, reached the surface and that reflected back to outer space at TOA. Since this process doesn't interact with other processes, it is called direct radiation effect. The clear sky downward SW and net SW fluxes at the surface in GRAPES_GFS of China Meteorological Administration are overestimated in Northern multitudes and Tropics. The main source of these errors is the absence of aerosol SW effect in GRAPES_GFS. The climatic aerosol mass concentration data, which include 13 kinds of aerosol and their 14 SW bands optical properties are considered in GRAPES_GFS. The calculated total optical depth, single scatter albedo and asymmetry factor are used as the input to radiation scheme. Compared with the satellite observation from MISER, the calculated total optical depth is in good consistent. The seasonal experiments show that, the summer averaged clear sky radiation fluxes at the surface are improved after including the SW effect of aerosol. The biases in the clear sky downward SW and net SW fluxes at the surface in Northern multitudes and Tropic reduced obviously. Furthermore, the weather forecast experiments also show that the skill scores in Northern hemisphere and East Asia also become better.
Radiation hydrodynamics of triggered star formation: the effect of the diffuse radiation field
NASA Astrophysics Data System (ADS)
Haworth, Thomas J.; Harries, Tim J.
2012-02-01
We investigate the effect of including diffuse field radiation when modelling the radiatively driven implosion of a Bonnor-Ebert sphere (BES). Radiation-hydrodynamical calculations are performed by using operator splitting to combine Monte Carlo photoionization with grid-based Eulerian hydrodynamics that includes self-gravity. It is found that the diffuse field has a significant effect on the nature of radiatively driven collapse which is strongly coupled to the strength of the driving shock that is established before impacting the BES. This can result in either slower or more rapid star formation than expected using the on-the-spot approximation depending on the distance of the BES from the source object. As well as directly compressing the BES, stronger shocks increase the thickness and density in the shell of accumulated material, which leads to short, strong, photoevaporative ejections that reinforce the compression whenever it slows. This happens particularly effectively when the diffuse field is included as rocket motion is induced over a larger area of the shell surface. The formation and evolution of 'elephant trunks' via instability is also found to vary significantly when the diffuse field is included. Since the perturbations that seed instabilities are smeared out elephant trunks form less readily and, once formed, are exposed to enhanced thermal compression.
NASA Astrophysics Data System (ADS)
Obara, Shin'ya
Investigation of a plant shoot configuration is used to obtain valuable information concerning the received light system. Additionally, analysis results concerning a plant shoot configuration interaction with direct solar radiation were taken from a past study. However, in order to consider a plant shoot as a received sunlight system, it is necessary to understand the received light characteristics of both direct solar radiation and diffused solar radiation. Under a clear sky, the ratio of direct solar radiation to diffused solar radiation is large. However, under a clouded sky, the amount of diffused solar radiation becomes larger. Therefore, in this paper, we investigate the received light characteristics of a plant shoot configuration under the influence of diffused solar radiation. As a result, we clarify the relationship between the amount of diffused solar radiation and the amount of received light as a function of the characteristics of the plant shoot configuration. In order to obtain diffused solar radiation, it is necessary to correspond to the radiation of the multi-directions. In the analysis, the characteristic of the difference in arrangement of the top leaf and the other leaf was obtained. Therefore, in analysis, leaves other than the top were distributed in the wide range.
Beardall, John; Sobrino, Cristina; Stojkovic, Slobodanka
2009-09-01
It is well known that UV radiation can cause deleterious effects to the physiological performance, growth and species assemblages of marine primary producers. In this review we describe the range of interactions observed between these impacts of ultraviolet radiation (UVR, 280-400 nm) with other environmental factors such as the availability of photosynthetically active radiation (PAR), nutrient status and levels of dissolved CO2, all of which can, in turn, be influenced by global climate change. Thus, increases in CO2 levels can affect the sensitivity of some species to UV-B radiation (UV-B), while others show no such impact on UV-B susceptibility. Both nitrogen- and phosphorus-limitation can have direct interactive effects on the susceptibility of algal cells and communities to UVR, though such effects are somewhat variable. Nutrient depletion can also potentially lead to a dominance of smaller celled species, which may be less able to screen out and are thus likely to be more susceptible to UVR-induced damage. The variability of responses to such interactions can lead to alterations in the species composition of algal assemblages.
NASA Technical Reports Server (NTRS)
Gulino, D. A.; Coles, C. E.
1986-01-01
The Liquid Droplet Radiator is one of several radiator systems currently under investigation by NASA Lewis Research Center. It involves the direct exposure of the radiator working fluid to the space environment. An area of concern is the potential harmful effects of the low-Earth-orbit atomic oxygen environment on the radiator working fluid. To address this issue, seven candidate fluids were exposed to an oxygen plasma environment in a laboratory plasma asher. The fluids studied included Dow Corning 705 Diffusion Pump Fluid, polymethylphenylsiloxane and polydimethlsiloxane, both of which are experimental fluids made by Dow Corning, Fomblin Z25, made by Montedison, and three fluids from the Krytox family of fluids, Krytox 143AB, 1502, and 16256, which are made by DuPont. The fluids were characterized by noting changes in visual appearance, physical state, mass, and infrared spectra. Of the fluids tested, the Fomblin and the three Krytoxes were the least affected by the oxygen plasma. The only effect noted was a change in mass, which was most likely due to an oxygen-catalyzed deploymerization of the fluid molecule.
Physical Processes and Applications of the Monte Carlo Radiative Energy Deposition (MRED) Code
NASA Astrophysics Data System (ADS)
Reed, Robert A.; Weller, Robert A.; Mendenhall, Marcus H.; Fleetwood, Daniel M.; Warren, Kevin M.; Sierawski, Brian D.; King, Michael P.; Schrimpf, Ronald D.; Auden, Elizabeth C.
2015-08-01
MRED is a Python-language scriptable computer application that simulates radiation transport. It is the computational engine for the on-line tool CRÈME-MC. MRED is based on c++ code from Geant4 with additional Fortran components to simulate electron transport and nuclear reactions with high precision. We provide a detailed description of the structure of MRED and the implementation of the simulation of physical processes used to simulate radiation effects in electronic devices and circuits. Extensive discussion and references are provided that illustrate the validation of models used to implement specific simulations of relevant physical processes. Several applications of MRED are summarized that demonstrate its ability to predict and describe basic physical phenomena associated with irradiation of electronic circuits and devices. These include effects from single particle radiation (including both direct ionization and indirect ionization effects), dose enhancement effects, and displacement damage effects. MRED simulations have also helped to identify new single event upset mechanisms not previously observed by experiment, but since confirmed, including upsets due to muons and energetic electrons.
Manda, Katrin; Glasow, Annegret; Paape, Daniel; Hildebrandt, Guido
2012-01-01
Dendritic cells (DCs), as professional antigen-presenting cells, are members of the innate immune system and function as key players during the induction phase of adaptive immune responses. Uptake, processing, and presentation of antigens direct the outcome toward either tolerance or immunity. The cells of the immune system are among the most highly radiosensitive cells in the body. For high doses of ionizing radiation (HD-IR) both immune-suppressive effects after whole body irradiation and possible immune activation during tumor therapy were observed. On the other hand, the effects of low doses of ionizing radiation (LD-IR) on the immune system are controversial and seem to show high variability among different individuals and species. There are reports revealing that protracted LD-IR can result in radioresistance. But immune-suppressive effects of chronic LD-IR are also reported, including the killing or sensitizing of certain cell types. This article shall review the current knowledge of radiation-induced effects on the immune system, paying special attention to the interaction of DCs and T cells.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Feng, Y.; Kotamarthi, V. R.; Coulter, R.
Aerosol radiative effects and thermodynamic responses over South Asia are examined with the Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) for March 2012. Model results of aerosol optical depths (AODs) and extinction profiles are analyzed and compared to satellite retrievals and two ground-based lidars located in northern India. The WRF-Chem model is found to heavily underestimate the AOD during the simulated pre-monsoon month and about 83 % of the model's low bias is due to aerosol extinctions below ~2 km. Doubling the calculated aerosol extinctions below 850 hPa generates much better agreement with the observed AOD and extinction profilesmore » averaged over South Asia. To separate the effect of absorption and scattering properties, two runs were conducted: in one run (Case I), the calculated scattering and absorption coefficients were increased proportionally, while in the second run (Case II) only the calculated aerosol scattering coefficient was increased. With the same AOD and extinction profiles, the two runs produce significantly different radiative effects over land and oceans. On the regional mean basis, Case I generates 48% more heating in the atmosphere and 21% more dimming at the surface than Case II. Case I also produces stronger cooling responses over the land from the longwave radiation adjustment and boundary layer mixing. These rapid adjustments offset the stronger radiative heating in Case I and lead to an overall lower-troposphere cooling up to -0.7K day −1, which is smaller than that in Case II. Over the ocean, direct radiative effects dominate the heating rate changes in the lower atmosphere lacking such surface and lower atmosphere adjustments due to fixed sea surface temperature, and the strongest atmospheric warming is obtained in Case I. Consequently, atmospheric dynamics (boundary layer heights and meridional circulation) and thermodynamic processes (water vapor and cloudiness) are shown to respond differently between Case I and Case II, underlining the importance of determining the exact portion of scattering or absorbing aerosols that lead to the underestimation of aerosol optical depth in the model. Additionally, the model results suggest that both the direct radiative effect and rapid thermodynamic responses need to be quantified for understanding aerosol radiative impacts.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Feng, Y.; Kotamarthi, V. R.; Coulter, R.
Aerosol radiative effects and thermodynamic responses over South Asia are examined with a version of the Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) for March 2012. Model results of Aerosol Optical Depth (AOD) and extinction profiles are analyzed and compared to satellite retrievals and two ground-based lidars located in the northern India. The WRF-Chem model is found to underestimate the AOD during the simulated pre-monsoon month and about 83 % of the model low-bias is due to aerosol extinctions below ~2 km. Doubling the calculated aerosol extinctions below 850 hPa generates much better agreement with the observed AODmore » and extinction profiles averaged over South Asia. To separate the effect of absorption and scattering properties, two runs were conducted: in one run (Case I), the calculated scattering and absorption coefficients were increased proportionally, while in the second run (Case II) only the calculated aerosol scattering coefficient was increased. With the same AOD and extinction profiles, the two runs produce significantly different radiative effects over land and oceans. On the regional mean basis, Case I generates 48 % more heating in the atmosphere and 21 % more dimming at the surface than Case II. Case I also produces stronger cooling responses over the land from the longwave radiation adjustment and boundary layer mixing. These rapid adjustments offset the stronger radiative heating in Case I and lead to an overall lower-troposphere cooling up to -0.7 K day −1, which is smaller than that in Case II. Over the ocean, direct radiative effects dominate the heating rate changes in the lower atmosphere lacking such surface and lower atmosphere adjustments due to fixed sea surface temperature, and the strongest atmospheric warming is obtained in Case I. Consequently, atmospheric dynamics (boundary layer heights and meridional circulation) and thermodynamic processes (water vapor and cloudiness) are shown to respond differently between Case I and Case II underlying the importance of determining the exact portion of scattering or absorbing aerosols that lead to the underestimation of aerosol optical depth in the model. In addition, the model results suggest that both direct radiative effect and rapid thermodynamic responses need to be quantified for understanding aerosol radiative impacts.« less
Feng, Y.; Kotamarthi, V. R.; Coulter, R.; ...
2016-01-18
Aerosol radiative effects and thermodynamic responses over South Asia are examined with the Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) for March 2012. Model results of aerosol optical depths (AODs) and extinction profiles are analyzed and compared to satellite retrievals and two ground-based lidars located in northern India. The WRF-Chem model is found to heavily underestimate the AOD during the simulated pre-monsoon month and about 83 % of the model's low bias is due to aerosol extinctions below ~2 km. Doubling the calculated aerosol extinctions below 850 hPa generates much better agreement with the observed AOD and extinction profilesmore » averaged over South Asia. To separate the effect of absorption and scattering properties, two runs were conducted: in one run (Case I), the calculated scattering and absorption coefficients were increased proportionally, while in the second run (Case II) only the calculated aerosol scattering coefficient was increased. With the same AOD and extinction profiles, the two runs produce significantly different radiative effects over land and oceans. On the regional mean basis, Case I generates 48% more heating in the atmosphere and 21% more dimming at the surface than Case II. Case I also produces stronger cooling responses over the land from the longwave radiation adjustment and boundary layer mixing. These rapid adjustments offset the stronger radiative heating in Case I and lead to an overall lower-troposphere cooling up to -0.7K day −1, which is smaller than that in Case II. Over the ocean, direct radiative effects dominate the heating rate changes in the lower atmosphere lacking such surface and lower atmosphere adjustments due to fixed sea surface temperature, and the strongest atmospheric warming is obtained in Case I. Consequently, atmospheric dynamics (boundary layer heights and meridional circulation) and thermodynamic processes (water vapor and cloudiness) are shown to respond differently between Case I and Case II, underlining the importance of determining the exact portion of scattering or absorbing aerosols that lead to the underestimation of aerosol optical depth in the model. Additionally, the model results suggest that both the direct radiative effect and rapid thermodynamic responses need to be quantified for understanding aerosol radiative impacts.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Feng, Y.; Kotamarthi, V. R.; Coulter, R.
Aerosol radiative effects and thermodynamic responses over South Asia are examined with the Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) for March 2012. Model results of aerosol optical depths (AODs) and extinction profiles are analyzed and compared to satellite retrievals and two ground-based lidars located in northern India. The WRF-Chem model is found to heavily underestimate the AOD during the simulated pre-monsoon month and about 83 % of the model's low bias is due to aerosol extinctions below ~2 km. Doubling the calculated aerosol extinctions below 850 hPa generates much better agreement with the observed AOD and extinction profilesmore » averaged over South Asia. To separate the effect of absorption and scattering properties, two runs were conducted: in one run (Case I), the calculated scattering and absorption coefficients were increased proportionally, while in the second run (Case II) only the calculated aerosol scattering coefficient was increased. With the same AOD and extinction profiles, the two runs produce significantly different radiative effects over land and oceans. On the regional mean basis, Case I generates 48 % more heating in the atmosphere and 21 % more dimming at the surface than Case II. Case I also produces stronger cooling responses over the land from the longwave radiation adjustment and boundary layer mixing. These rapid adjustments offset the stronger radiative heating in Case I and lead to an overall lower-troposphere cooling up to -0.7 K day −1, which is smaller than that in Case II. Over the ocean, direct radiative effects dominate the heating rate changes in the lower atmosphere lacking such surface and lower atmosphere adjustments due to fixed sea surface temperature, and the strongest atmospheric warming is obtained in Case I. Consequently, atmospheric dynamics (boundary layer heights and meridional circulation) and thermodynamic processes (water vapor and cloudiness) are shown to respond differently between Case I and Case II, underlining the importance of determining the exact portion of scattering or absorbing aerosols that lead to the underestimation of aerosol optical depth in the model. In addition, the model results suggest that both the direct radiative effect and rapid thermodynamic responses need to be quantified for understanding aerosol radiative impacts.« less
Feng, Y.; Kotamarthi, V. R.; Coulter, R.; ...
2015-06-19
Aerosol radiative effects and thermodynamic responses over South Asia are examined with a version of the Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) for March 2012. Model results of Aerosol Optical Depth (AOD) and extinction profiles are analyzed and compared to satellite retrievals and two ground-based lidars located in the northern India. The WRF-Chem model is found to underestimate the AOD during the simulated pre-monsoon month and about 83 % of the model low-bias is due to aerosol extinctions below ~2 km. Doubling the calculated aerosol extinctions below 850 hPa generates much better agreement with the observed AODmore » and extinction profiles averaged over South Asia. To separate the effect of absorption and scattering properties, two runs were conducted: in one run (Case I), the calculated scattering and absorption coefficients were increased proportionally, while in the second run (Case II) only the calculated aerosol scattering coefficient was increased. With the same AOD and extinction profiles, the two runs produce significantly different radiative effects over land and oceans. On the regional mean basis, Case I generates 48 % more heating in the atmosphere and 21 % more dimming at the surface than Case II. Case I also produces stronger cooling responses over the land from the longwave radiation adjustment and boundary layer mixing. These rapid adjustments offset the stronger radiative heating in Case I and lead to an overall lower-troposphere cooling up to -0.7 K day −1, which is smaller than that in Case II. Over the ocean, direct radiative effects dominate the heating rate changes in the lower atmosphere lacking such surface and lower atmosphere adjustments due to fixed sea surface temperature, and the strongest atmospheric warming is obtained in Case I. Consequently, atmospheric dynamics (boundary layer heights and meridional circulation) and thermodynamic processes (water vapor and cloudiness) are shown to respond differently between Case I and Case II underlying the importance of determining the exact portion of scattering or absorbing aerosols that lead to the underestimation of aerosol optical depth in the model. In addition, the model results suggest that both direct radiative effect and rapid thermodynamic responses need to be quantified for understanding aerosol radiative impacts.« less
NASA Astrophysics Data System (ADS)
Bauer, Susanne E.; Menon, Surabi
2012-01-01
The anthropogenic increase in aerosol concentrations since preindustrial times and its net cooling effect on the atmosphere is thought to mask some of the greenhouse gas-induced warming. Although the overall effect of aerosols on solar radiation and clouds is most certainly negative, some individual forcing agents and feedbacks have positive forcing effects. Recent studies have tried to identify some of those positive forcing agents and their individual emission sectors, with the hope that mitigation policies could be developed to target those emitters. Understanding the net effect of multisource emitting sectors and the involved cloud feedbacks is very challenging, and this paper will clarify forcing and feedback effects by separating direct, indirect, semidirect and surface albedo effects due to aerosols. To this end, we apply the Goddard Institute for Space Studies climate model including detailed aerosol microphysics to examine aerosol impacts on climate by isolating single emission sector contributions as given by the Coupled Model Intercomparison Project Phase 5 (CMIP5) emission data sets developed for Intergovernmental Panel on Climate Change (IPCC) AR5. For the modeled past 150 years, using the climate model and emissions from preindustrial times to present-day, the total global annual mean aerosol radiative forcing is -0.6 W/m2, with the largest contribution from the direct effect (-0.5 W/m2). Aerosol-induced changes on cloud cover often depends on cloud type and geographical region. The indirect (includes only the cloud albedo effect with -0.17 W/m2) and semidirect effects (-0.10 W/m2) can be isolated on a regional scale, and they often have opposing forcing effects, leading to overall small forcing effects on a global scale. Although the surface albedo effects from aerosols are small (0.016 W/m2), triggered feedbacks on top of the atmosphere (TOA) radiative forcing can be 10 times larger. Our results point out that each emission sector has varying impacts by geographical region. For example, the single sector most responsible for a net positive radiative forcing is the transportation sector in the United States, agricultural burning and transportation in Europe, and the domestic emission sector in Asia. These sectors are attractive mitigation targets.
NASA Technical Reports Server (NTRS)
Bauer, Susanne E.; Menon, Surabi
2012-01-01
The anthropogenic increase in aerosol concentrations since preindustrial times and its net cooling effect on the atmosphere is thought to mask some of the greenhouse gas-induced warming. Although the overall effect of aerosols on solar radiation and clouds is most certainly negative, some individual forcing agents and feedbacks have positive forcing effects. Recent studies have tried to identify some of those positive forcing agents and their individual emission sectors, with the hope that mitigation policies could be developed to target those emitters. Understanding the net effect of multisource emitting sectors and the involved cloud feedbacks is very challenging, and this paper will clarify forcing and feedback effects by separating direct, indirect, semidirect and surface albedo effects due to aerosols. To this end, we apply the Goddard Institute for Space Studies climate model including detailed aerosol microphysics to examine aerosol impacts on climate by isolating single emission sector contributions as given by the Coupled Model Intercomparison Project Phase 5 (CMIP5) emission data sets developed for Intergovernmental Panel on Climate Change (IPCC) AR5. For the modeled past 150 years, using the climate model and emissions from preindustrial times to present-day, the total global annual mean aerosol radiative forcing is -0.6 W/m(exp 2), with the largest contribution from the direct effect (-0.5 W/m(exp 2)). Aerosol-induced changes on cloud cover often depends on cloud type and geographical region. The indirect (includes only the cloud albedo effect with -0.17 W/m(exp 2)) and semidirect effects (-0.10 W/m(exp 2)) can be isolated on a regional scale, and they often have opposing forcing effects, leading to overall small forcing effects on a global scale. Although the surface albedo effects from aerosols are small (0.016 W/m(exp 2)), triggered feedbacks on top of the atmosphere (TOA) radiative forcing can be 10 times larger. Our results point out that each emission sector has varying impacts by geographical region. For example, the single sector most responsible for a net positive radiative forcing is the transportation sector in the United States, agricultural burning and transportation in Europe, and the domestic emission sector in Asia. These sectors are attractive mitigation targets.
Angular radiation models for Earth-atmosphere system. Volume 1: Shortwave radiation
NASA Technical Reports Server (NTRS)
Suttles, J. T.; Green, R. N.; Minnis, P.; Smith, G. L.; Staylor, W. F.; Wielicki, B. A.; Walker, I. J.; Young, D. F.; Taylor, V. R.; Stowe, L. L.
1988-01-01
Presented are shortwave angular radiation models which are required for analysis of satellite measurements of Earth radiation, such as those fro the Earth Radiation Budget Experiment (ERBE). The models consist of both bidirectional and directional parameters. The bidirectional parameters are anisotropic function, standard deviation of mean radiance, and shortwave-longwave radiance correlation coefficient. The directional parameters are mean albedo as a function of Sun zenith angle and mean albedo normalized to overhead Sun. Derivation of these models from the Nimbus 7 ERB (Earth Radiation Budget) and Geostationary Operational Environmental Satellite (GOES) data sets is described. Tabulated values and computer-generated plots are included for the bidirectional and directional modes.
Wang, Bing; Katsube, Takanori; Begum, Nasrin; Nenoi, Mitsuru
2016-07-01
Both psychological stress (PS) and ionizing radiation (IR) cause varied detrimental effects on humans. There has been no direct evidence so far showing PS alone could cause cancer; however, long-lasting PS may affect our overall health and ability to cope with cancer. Due to their living conditions and occupations, some people may encounter concurrent exposure to both PS and IR to a high extent. In addition to possible health effects resulting directly from exposure to IR on these people, fear of IR exposure is also a cause of PS. The question of whether PS would influence susceptibility to IR, radiocarcinogenesis in particular, is of great concern by both the academic world and the public. Recently, investigations using animal PS models demonstrated that PS could modulate susceptibility to IR, causing increased susceptibility to radiocarcinogenesis in Trp53-heterozygous mice, hematological toxicity in peripheral blood and elevated chromosome aberration (dicentrics) frequency in splenocytes of Trp53-wild-type mice. To actively reduce health risk from exposure to IR, further studies are needed to cumulate more evidence and provide insights into the mechanisms underlying the alterations in susceptibility due to PS modulation. This mini-review gives a general overview of the significance of PS effects on humans and experimental animals, with a special focus on summarizing the latest weight-of-evidence approaches to radiobiological studies on PS-induced alterations in susceptibility in experimental animal models. The susceptibility being investigated is mainly in the context of the impact of the modulatory effect of PS on radiocarcinogenesis; we seek to improve understanding of the combined effects of exposure to both PS and IR in order to facilitate, via active intervention, strategies for radiation risk reduction. © The Author 2016. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.
Simultaneous Retrieval of Multiple Aerosol Parameters Using a Multi-Angular Approach
NASA Technical Reports Server (NTRS)
Kuo, K.-S.; Weger, R. C.; Welch, R. M.
1997-01-01
Atmospheric aerosol particles, both natural and anthropogenic, are important to the earth's radiative balance through their direct and indirect effects. They scatter the incoming solar radiation (direct effect) and modify the shortwave reflective properties of clouds by acting as cloud condensation nuclei (indirect effect). Although it has been suggested that aerosols exert a net cooling influence on climate, this effect has received less attention than the radiative forcing due to clouds and greenhouse gases. In order to understand the role that aerosols play in a changing climate, detailed and accurate observations are a prerequisite. The retrieval of aerosol optical properties by satellite remote sensing has proven to be a difficult task. The difficulty results mainly from the tenuous nature and variable composition of aerosols. To date, with single-angle satellite observations, we can only retrieve reliably against dark backgrounds, such as over oceans and dense vegetation. Even then, assumptions must be made concerning the chemical composition of aerosols. In this investigation we examine the feasibility of simultaneous retrieval of multiple aerosol optical parameters using reflectances from a typical set of twelve angles observed by the French POLDER instrument. The retrieved aerosol optical parameters consist of asymmetry factor, single scattering albedo, surface albedo, and optical thickness.
NASA Technical Reports Server (NTRS)
Gregg, Watson W.; Rousseaux, Cecile S.
2016-01-01
The importance of including directional and spectral light in simulations of ocean radiative transfer was investigated using a coupled biogeochemical-circulation-radiative model of the global oceans. The effort focused on phytoplankton abundances, nutrient concentrations and vertically-integrated net primary production. The importance was approached by sequentially removing directional (i.e., direct vs. diffuse) and spectral irradiance and comparing results of the above variables to a fully directionally and spectrally-resolved model. In each case the total irradiance was kept constant; it was only the pathways and spectral nature that were changed. Assuming all irradiance was diffuse had negligible effect on global ocean primary production. Global nitrate and total chlorophyll concentrations declined by about 20% each. The largest changes occurred in the tropics and sub-tropics rather than the high latitudes, where most of the irradiance is already diffuse. Disregarding spectral irradiance had effects that depended upon the choice of attenuation wavelength. The wavelength closest to the spectrally-resolved model, 500 nm, produced lower nitrate (19%) and chlorophyll (8%) and higher primary production (2%) than the spectral model. Phytoplankton relative abundances were very sensitive to the choice of non-spectral wavelength transmittance. The combined effects of neglecting both directional and spectral irradiance exacerbated the differences, despite using attenuation at 500 nm. Global nitrate decreased 33% and chlorophyll decreased 24%. Changes in phytoplankton community structure were considerable, representing a change from chlorophytes to cyanobacteria and coccolithophores. This suggested a shift in community function, from light-limitation to nutrient limitation: lower demands for nutrients from cyanobacteria and coccolithophores favored them over the more nutrient-demanding chlorophytes. Although diatoms have the highest nutrient demands in the model, their relative abundances were generally unaffected because they only prosper in nutrient-rich regions, such as the high latitudes and upwelling regions, which showed the fewest effects from the changes in radiative simulations. The results showed that including directional and spectral irradiance when simulating the ocean light field can be important for ocean biology, but the magnitude varies with variables and regions. The quantitative results are intended to assist ocean modelers when considering improved irradiance representations relative to other processes or variables associated with the issues of interest.
Comparison of human radiation exchange models in outdoor areas
NASA Astrophysics Data System (ADS)
Park, Sookuk; Tuller, Stanton E.
2011-10-01
Results from the radiation components of seven different human thermal exchange models/methods are compared. These include the Burt, COMFA, MENEX, OUT_SET* and RayMan models, the six-directional method and the new Park and Tuller model employing projected area factors ( f p) and effective radiation area factors ( f eff) determined from a sample of normal- and over-weight Canadian Caucasian adults. Input data include solar and longwave radiation measured during a clear summer day in southern Ontario. Variations between models came from differences in f p and f eff and different estimates of longwave radiation from the open sky. The ranges between models for absorbed solar, net longwave and net all-wave radiation were 164, 31 and 187 W m-2, respectively. These differentials between models can be significant in total human thermal exchange. Therefore, proper f p and f eff values should be used to make accurate estimation of radiation on the human body surface.
Electron-proton spectrometer: Summary for critical design review
NASA Technical Reports Server (NTRS)
1972-01-01
The electron-proton spectrometer (EPS) is mounted external to the Skylab module complex on the command service module. It is designed to make a 2 pi omni-directional measurement of electrons and protons which result from solar flares or enhancement of the radiation belts. The EPS data will provide accurate radiation dose information so that uncertain Relative biological effectiveness factors are eliminated by measuring the external particle spectra. Astronaut radiation safety, therefore, can be ensured, as the EPS data can be used to correct or qualify radiation dose measurements recorded by other radiation measuring instrumentation within the Skylab module complex. The EPS has the capability of measuring and extremely wide dynamic radiation dose rate range, approaching 10 to the 7th power. Simultaneously the EPS has the capability to process data from extremely high radiation fields such as might be encountered in the wake of an intense solar flare.
Williams, Rachel; Schofield, Amy; Holder, Gareth; Downes, Joan; Edgar, David; Harrison, Paul; Siggel-King, Michele; Surman, Mark; Dunning, David; Hill, Stephen; Holder, David; Jackson, Frank; Jones, James; McKenzie, Julian; Saveliev, Yuri; Thomsen, Neil; Williams, Peter; Weightman, Peter
2013-01-21
Understanding the influence of exposure of biological systems to THz radiation is becoming increasingly important. There is some evidence to suggest that THz radiation can influence important activities within mammalian cells. This study evaluated the influence of the high peak power, low average power THz radiation produced by the ALICE (Daresbury Laboratory, UK) synchrotron source on human epithelial and embryonic stem cells. The cells were maintained under standard tissue culture conditions, during which the THz radiation was delivered directly into the incubator for various exposure times. The influence of the THz radiation on cell morphology, attachment, proliferation and differentiation was evaluated. The study demonstrated that there was no difference in any of these parameters between irradiated and control cell cultures. It is suggested that under these conditions the cells are capable of compensating for any effects caused by exposure to THz radiation with the peak powers levels employed in these studies.
SAS 2 observations of the earth albedo gamma radiation above 35 MeV
NASA Technical Reports Server (NTRS)
Thompson, D. J.; Simpson, G. A.; Ozel, M. E.
1981-01-01
The earth albedo gamma radiation above 35 MeV in the equatorial region is investigated using observations from the second Small Astronomy Satellite. The zenith angle distribution of the gamma radiation has a peak toward the horizon which is about an order of magnitude more intense than the radiation coming from the nadir, and nearly two orders of magnitude more intense than the gamma radiation from most parts of the sky. The gamma radiation originating from the western horizon is a factor of four more intense than the radiation from the eastern horizon and a factor of three more intense than that from the northern and southern directions. This reflects the geomagnetic effects on the incident cosmic rays whose interactions produce the albedo gamma rays. The variation of the upcoming gamma ray intensity with vertical cutoff rigidity is consistent with the empirical relationship found by Gur'yan et al. (1979).
Optical radiation measurements and instrumentation.
Andersen, F A; Landry, R J
1981-07-01
Accurate measurement of optical radiation is required when sources of optical radiation are used in biological research. Such measurement of broad-band noncoherent optical radiations usually must be performed by a highly trained specialist using sophisticated, complex, and expensive instruments. Presentation of the results of such measurement requires correct use of quantities and units with which many biological researchers are unfamiliar. The measurement process, quantities, units, measurement systems and instruments, and uncertainties associated with optical radiation measurements are reviewed in this paper. A conventional technique for evaluating the potential hazards associated with broad-band sources of optical radiation and a spectroradiometer developed to measure spectral quantities is described. A new prototype ultraviolet radiation hazard monitor which has recently been developed is also presented. This new instrument utilizes a spectrograph and a spectral weighting mechanical mask and provides a direct reading of the effective irradiance for wavelengths less than 315 nm.
NASA Astrophysics Data System (ADS)
Tu, W.; Reeves, G. D.; Cunningham, G.; Selesnick, R. S.; Li, X.; Looper, M. D.
2012-12-01
Since its launch in 1992, SAMPEX has been continuously providing measurements of radiation belt electrons at low altitude, which are not only ideal for the direct quantification of the electron precipitation loss in the radiation belt, but also provide data coverage in a critical region for global radiation belt data assimilation models. However, quantitatively combining high-altitude and low-earth-orbit (LEO) measurements on the same L-shell is challenging because LEO measurements typically contain a dynamic mixture of trapped and precipitating populations. Specifically, the electrons measured by SAMPEX can be distinguished as trapped, quasi-trapped (in the drift loss cone), and precipitating (in the bounce loss cone). To simulate the low-altitude electron distribution observed by SAMPEX/PET, a drift-diffusion model has been developed that includes the effects of azimuthal drift and pitch angle diffusion. The simulation provides direct quantification of the rates and variations of electron loss to the atmosphere, a direct input to our Dynamic Radiation Environment Assimilation Model (DREAM) as the electron loss lifetimes. The current DREAM uses data assimilation to combine a 1D radial diffusion model with observational data of radiation belt electrons. In order to implement the mixed electron measurements from SAMPEX into DREAM, we need to map the SAMPEX data from low altitude to high altitudes. To perform the mapping, we will first examine the well-known 'global coherence' of radiation belt electrons by comparing SAMPEX electron fluxes with the energetic electron data from LANL GEO and GPS spacecraft. If the correlation is good, we can directly map the SAMPEX fluxes to high altitudes based on the global coherence; if not, we will use the derived pitch angle distribution from the drift-diffusion model to map up the field and test the mapping by comparing to the high-altitude flux measurements. Then the globally mapped electron fluxes can be assimilated into DREAM. This new implementation of SAMPEX data will greatly augment the data coverage of DREAM and contribute to the global specification of the radiation belt environment.
NASA Technical Reports Server (NTRS)
Barcellos-Hoff, M. H.; Brooks, A. L.; Chatterjee, A. (Principal Investigator)
2001-01-01
Cell growth, differentiation and death are directed in large part by extracellular signaling through the interactions of cells with other cells and with the extracellular matrix; these interactions are in turn modulated by cytokines and growth factors, i.e. the microenvironment. Here we discuss the idea that extracellular signaling integrates multicellular damage responses that are important deterrents to the development of cancer through mechanisms that eliminate abnormal cells and inhibit neoplastic behavior. As an example, we discuss the action of transforming growth factor beta (TGFB1) as an extracellular sensor of damage. We propose that radiation-induced bystander effects and genomic instability are, respectively, positive and negative manifestations of this homeostatic process. Bystander effects exhibited predominantly after a low-dose or a nonhomogeneous radiation exposure are extracellular signaling pathways that modulate cellular repair and death programs. Persistent disruption of extracellular signaling after exposure to relatively high doses of ionizing radiation may lead to the accumulation of aberrant cells that are genomically unstable. Understanding radiation effects in terms of coordinated multicellular responses that affect decisions regarding the fate of a cell may necessitate re-evaluation of radiation dose and risk concepts and provide avenues for intervention.
aerosol radiative effects and forcing: spatial and temporal distributions
NASA Astrophysics Data System (ADS)
Kinne, Stefan
2014-05-01
A monthly climatology for aerosol optical properties based on a synthesis from global modeling and observational data has been applied to illustrate spatial distributions and global averages of aerosol radiative impacts. With the help of a pre-industrial reference for aerosol optical properties from global modeling, also the aerosol direct forcing (ca -0.35W/m2 globally and annual averaged) and their spatial and seasonal distributions and contributions by individual aerosol components are estimated. Finally, CCN and IN concentrations associated with this climatology are applied to estimate aerosol indirect effects and forcing.
Simulating Space Radiation-Induced Breast Tumor Incidence Using Automata.
Heuskin, A C; Osseiran, A I; Tang, J; Costes, S V
2016-07-01
Estimating cancer risk from space radiation has been an ongoing challenge for decades primarily because most of the reported epidemiological data on radiation-induced risks are derived from studies of atomic bomb survivors who were exposed to an acute dose of gamma rays instead of chronic high-LET cosmic radiation. In this study, we introduce a formalism using cellular automata to model the long-term effects of ionizing radiation in human breast for different radiation qualities. We first validated and tuned parameters for an automata-based two-stage clonal expansion model simulating the age dependence of spontaneous breast cancer incidence in an unexposed U.S. We then tested the impact of radiation perturbation in the model by modifying parameters to reflect both targeted and nontargeted radiation effects. Targeted effects (TE) reflect the immediate impact of radiation on a cell's DNA with classic end points being gene mutations and cell death. They are well known and are directly derived from experimental data. In contrast, nontargeted effects (NTE) are persistent and affect both damaged and undamaged cells, are nonlinear with dose and are not well characterized in the literature. In this study, we introduced TE in our model and compared predictions against epidemiologic data of the atomic bomb survivor cohort. TE alone are not sufficient for inducing enough cancer. NTE independent of dose and lasting ∼100 days postirradiation need to be added to accurately predict dose dependence of breast cancer induced by gamma rays. Finally, by integrating experimental relative biological effectiveness (RBE) for TE and keeping NTE (i.e., radiation-induced genomic instability) constant with dose and LET, the model predicts that RBE for breast cancer induced by cosmic radiation would be maximum at 220 keV/μm. This approach lays the groundwork for further investigation into the impact of chronic low-dose exposure, inter-individual variation and more complex space radiation scenarios.
Radiator debris removing apparatus and work machine using same
Martin, Kevin L [Washburn, IL; Elliott, Dwight E [Chillicothe, IL
2008-09-02
A radiator assembly includes a finned radiator core and a debris removing apparatus having a compressed air inlet and at least one compressed air outlet configured to direct compressed air through the radiator core. A work machine such as a wheel loader includes a radiator and a debris removing apparatus coupled with on-board compressed air and having at least one pressurized gas outlet configured to direct a gas toward the face of the radiator.
The influence of direct mobile phone radiation on sperm quality.
Gorpinchenko, Igor; Nikitin, Oleg; Banyra, Oleg; Shulyak, Alexander
2014-01-01
It is impossible to imagine a modern socially-active man who does not use mobile devices and/or computers with Wi-Fi function. The effect of mobile phone radiation on male fertility is the subject of recent interest and investigations. The aim of this study was to investigate the direct in vitro influence of mobile phone radiation on sperm DNA fragmentation and motility parameters in healthy subjects with normozoospermia. 32 healthy men with normal semen parameters were selected for the study. Each sperm sample was divided into two equal portions (A and B). Portions A of all involved men were placed for 5 hours in a thermostat, and portions B were placed into a second thermostat for the same period of time, where a mobile phone in standby/talk mode was placed. After 5 hours of incubation the sperm samples from both thermostats were re-evaluated regarding basic motility parameters. The presence of DNA fragmentation in both A and B portions of each sample was determined each hour using a standard sperm chromatin dispersion test. The number of spermatozoa with progressive movement in the group, influenced by electromagnetic radiation, is statistically lower than the number of spermatozoa with progressive movement in the group under no effect of the mobile phone. The number of non-progressive movement spermatozoa was significantly higher in the group, which was influenced by cell phone radiation. The DNA fragmentation was also significantly higher in this group. A correlation exists between mobile phone radiation exposure, DNA-fragmentation level and decreased sperm motility.
The influence of direct mobile phone radiation on sperm quality
Gorpinchenko, Igor; Nikitin, Oleg; Shulyak, Alexander
2014-01-01
Introduction It is impossible to imagine a modern socially–active man who does not use mobile devices and/or computers with Wi–Fi function. The effect of mobile phone radiation on male fertility is the subject of recent interest and investigations. The aim of this study was to investigate the direct in vitro influence of mobile phone radiation on sperm DNA fragmentation and motility parameters in healthy subjects with normozoospermia. Material and methods 32 healthy men with normal semen parameters were selected for the study. Each sperm sample was divided into two equal portions (A and B). Portions A of all involved men were placed for 5 hours in a thermostat, and portions B were placed into a second thermostat for the same period of time, where a mobile phone in standby/talk mode was placed. After 5 hours of incubation the sperm samples from both thermostats were re–evaluated regarding basic motility parameters. The presence of DNA fragmentation in both A and B portions of each sample was determined each hour using a standard sperm chromatin dispersion test. Results The number of spermatozoa with progressive movement in the group, influenced by electromagnetic radiation, is statistically lower than the number of spermatozoa with progressive movement in the group under no effect of the mobile phone. The number of non–progressive movement spermatozoa was significantly higher in the group, which was influenced by cell phone radiation. The DNA fragmentation was also significantly higher in this group. Conclusions A correlation exists between mobile phone radiation exposure, DNA–fragmentation level and decreased sperm motility. PMID:24982785
Solar radiation on a catenary collector
NASA Technical Reports Server (NTRS)
Crutchik, M.; Appelbaum, J.
1992-01-01
A tent-shaped structure with a flexible photovoltaic blanket acting as a catenary collector is presented. The shadow cast by one side of the collector produces a shadow on the other side of the collector. This self-shading effect is analyzed. The direct beam, the diffuse, and the albedo radiation on the collector are determined. An example is given for the insolation on the collector operating on Viking Lander 1 (VL1).
Chemical, Biological, Radiological, Nuclear, and High-Yield Explosives Consequences Management
2006-10-02
cause three types of injuries: blast, thermal and radiation, as well as electromagnetic pulse (EMP) effects described further in a later section. (1...occur with conventional explosives and are further described in the next section. (2) Thermal injuries present as flash burns (burns from direct...exposure to the thermal radiation pulse, typically ultraviolet, visible, and infrared waves) or flame burns (burns from materials set afire by the infrared
A Design of Experiments Investigation of Offset Streams for Supersonic Jet Noise Reduction
NASA Technical Reports Server (NTRS)
Henderson, Brenda; Papamoschou, Dimitri
2014-01-01
An experimental investigation into the noise characteristics of a dual-stream jet with four airfoils inserted in the fan nozzle was conducted. The intent of the airfoils was to deflect the fan stream relative to the core stream and, therefore, impact the development of the secondary potential core and noise radiated in the peak jet-noise direction. The experiments used a full-factorial Design of Experiments (DoE) approach to identify parameters and parameter interactions impacting noise radiation at two azimuthal microphone array locations, one of which represented a sideline viewing angle. The parameters studied included airfoil angle-of-attack, airfoil azimuthal location within the fan nozzle, and airfoil axial location relative to the fan-nozzle trailing edge. Jet conditions included subsonic and supersonic fan-stream Mach numbers. Heated jets conditions were simulated with a mixture of helium and air to replicate the exhaust velocity and density of the hot jets. The introduction of the airfoils was shown to impact noise radiated at polar angles in peak-jet noise direction and to have no impact on noise radiated at small and broadside polar angles and to have no impact on broadband-shock-associated noise. The DoE analysis showed the main effects impacting noise radiation at sideline-azimuthal-viewing angles included airfoil azimuthal angle for the airfoils on the lower side of the jet near the sideline array and airfoil trailing edge distance (with airfoils located at the nozzle trailing edge produced the lowest sound pressure levels). For an array located directly beneath the jet (and on the side of the jet from which the fan stream was deflected), the main effects impacting noise radiation included airfoil angle-of-attack and airfoil azimuthal angle for the airfoils located on the observation side of the jet as well and trailing edge distance. Interaction terms between multiple configuration parameters were shown to have significant impact on the radiated noise. The models were shown to adequately describe the sound-pressure levels obtained for a configuration in the center of the design space indicating the models can be used to navigate the design space.
Femtosecond laser polishing of optical materials
NASA Astrophysics Data System (ADS)
Taylor, Lauren L.; Qiao, Jun; Qiao, Jie
2015-10-01
Technologies including magnetorheological finishing and CNC polishing are commonly used to finish optical elements, but these methods are often expensive, generate waste through the use of fluids or abrasives, and may not be suited for specific freeform substrates due to the size and shape of finishing tools. Pulsed laser polishing has been demonstrated as a technique capable of achieving nanoscale roughness while offering waste-free fabrication, material-specific processing through direct tuning of laser radiation, and access to freeform shapes using refined beam delivery and focusing techniques. Nanosecond and microsecond pulse duration radiation has been used to perform successful melting-based polishing of a variety of different materials, but this approach leads to extensive heat accumulation resulting in subsurface damage. We have experimentally investigated the ability of femtosecond laser radiation to ablate silicon carbide and silicon. By substituting ultrafast laser radiation, polishing can be performed by direct evaporation of unwanted surface asperities with minimal heating and melting, potentially offering damage-free finishing of materials. Under unoptimized laser processing conditions, thermal effects can occur leading to material oxidation. To investigate these thermal effects, simulation of the heat accumulation mechanism in ultrafast laser ablation was performed. Simulations have been extended to investigate the optimum scanning speed and pulse energy required for processing various substrates. Modeling methodologies and simulation results will be presented.
NASA Astrophysics Data System (ADS)
Gkikas, Antonis; Obiso, Vincenzo; Vendrell, Lluis; Basart, Sara; Jorba, Oriol; Pérez Garcia-Pando, Carlos; Hatzianastassiou, Nikos; Gassó, Santiago; Baldasano, Jose Maria
2016-04-01
Throughout the year, under favorable conditions, massive loads of mineral particles originating in the northern African and Middle East deserts are transported over the Mediterranean basin. Due to their composition and size, dust aerosols perturb the Earth-Atmosphere system's energy budget interacting directly with the shortwave (SW) and longwave (LW) radiation. The present study aims to compute the Mediterranean dust outbreaks' direct radiative effects (DREs) as well as to assess the effect of including dust DREs in numerical simulations of a regional model. To this aim, 20 intense dust outbreaks have been selected based on their spatial coverage and intensity. Their identification, over the period 2000-2013, has been achieved through an objective and dynamic algorithm which utilizes as inputs daily satellite retrievals derived by the MODIS-Terra, EP-TOMS and OMI-Aura sensors. For each outbreak, two simulations of the NMMB/BSC-Dust model were made for a forecast period of 84 hours, with the model initialized at 00 UTC of the day when the dust outbreak was ignited, activating (RADON) and deactivating (RADOFF) dust-radiation interactions. The simulation domain covers the northern Africa, the Middle East and Europe at 0.25° x 0.25° horizontal resolution, for 40 hybrid sigma pressure levels up to 50 hPa. The instantaneous and regional DREs have been calculated at the top of the atmosphere (TOA), into the atmosphere (ATMAB), and at surface, for the downwelling (SURF) and the absorbed (NETSURF) radiation, for the SW, LW and NET (SW+LW) radiation. The interaction between dust aerosols and NET radiation, locally leads to an atmospheric warming (DREATMAB) by up to 150 Wm-2, a surface cooling (DRENETSURF) by up to 250 Wm-2 and a reduction of the downwelling radiation at the surface (DRESURF) by up to 300 Wm-2. At TOA, DREs are mainly negative (down to -150 Wm-2) indicating a cooling of the Earth-Atmosphere system, although positive values (up to 50 Wm-2) are encountered over desert areas. The mean regional NET DREs, under clear-sky conditions, vary between -10 to 2, -3 to 25, -35 to 3 and -22 to 3 Wm-2 for TOA, ATMAB, SURF and NETSURF, respectively. According to our results, dust outbreaks can cause a decrease of temperature at 2 meters by 4 °C during daytime while an increase of a similar magnitude is found at night. Moreover, negative feedbacks on dust emissions and aerosol optical depth are observed when dust-radiation interactions are activated. Our analysis clearly shows that taking into account the dust radiative effects in numerical simulations (RADON) the model's ability to reproduce the temperature fields as well as the downwelling radiation fluxes at the surface is improved. The former is confirmed by the evaluation of the model's outputs against ERA-Interim reanalyses datasets and weather stations observations (Integrated Surface Database, ISD) while the latter is justified through the comparison of model's downwelling SW/LW radiation fluxes at the surface with ground measurements from 6 Baseline Surface Radiation Network (BSRN) stations. A similar analysis is also attempted for the dust aerosol optical depth at 550 nm using the AERONET ground retrievals as reference measurements.
Area X-ray or UV camera system for high-intensity beams
Chapman, Henry N.; Bajt, Sasa; Spiller, Eberhard A.; Hau-Riege, Stefan , Marchesini, Stefano
2010-03-02
A system in one embodiment includes a source for directing a beam of radiation at a sample; a multilayer mirror having a face oriented at an angle of less than 90 degrees from an axis of the beam from the source, the mirror reflecting at least a portion of the radiation after the beam encounters a sample; and a pixellated detector for detecting radiation reflected by the mirror. A method in a further embodiment includes directing a beam of radiation at a sample; reflecting at least some of the radiation diffracted by the sample; not reflecting at least a majority of the radiation that is not diffracted by the sample; and detecting at least some of the reflected radiation. A method in yet another embodiment includes directing a beam of radiation at a sample; reflecting at least some of the radiation diffracted by the sample using a multilayer mirror; and detecting at least some of the reflected radiation.
Spectral and Polarimetric Imagery Collection Experiment
2011-12-01
Also melted snow liquid rate Optical rain gauge Rain rate Possibly snow rate Visibility meter Visibility Smoke, fog, haze Pyranometer Sun and sky...performance of the IR imagery due to thermal effect or possible inversion layer effects. Pyranometers measure total sun and sky radiation. If the direction
Geometrical Effects on the Electromagnetic Radiation from Lightning Return Strokes
NASA Technical Reports Server (NTRS)
Willett, John C.; Smith, David A.; LeVine, David M.; Zukor, Dorothy J. (Technical Monitor)
2000-01-01
The Los Alamos National Laboratory (LANL) Sferic Array has recorded electric-field-change waveforms simultaneously at several stations surrounding the ground-strike points of numerous return strokes in cloud-to-ground lightning flashes. Such data are available from the five-station sub-networks in both Florida and New Mexico. With these data it has been possible for the first time to compare the waveforms radiated in different directions by a given stroke. Such comparisons are of interest to assess both the effects of channel geometry on the fine structure of subsequent-stroke radiation fields and the role of branches in the more jagged appearance of first-stroke waveforms. This paper presents multiple-station, time-domain waveforms with a 200 Hz to 500 kHz pass-band from both first and subsequent return strokes at ranges generally between 100 and 200 km. The differences among waveforms of the same stroke received at stations in different directions from the lightning channel are often obvious. These differences are illustrated and interpreted in the context of channel tortuosity and branches.
NASA Technical Reports Server (NTRS)
Redemann, Jens
2018-01-01
Globally, aerosols remain a major contributor to uncertainties in assessments of anthropogenically-induced changes to the Earth climate system, despite concerted efforts using satellite and suborbital observations and increasingly sophisticated models. The quantification of direct and indirect aerosol radiative effects, as well as cloud adjustments thereto, even at regional scales, continues to elude our capabilities. Some of our limitations are due to insufficient sampling and accuracy of the relevant observables, under an appropriate range of conditions to provide useful constraints for modeling efforts at various climate scales. In this talk, I will describe (1) the efforts of our group at NASA Ames to develop new airborne instrumentation to address some of the data insufficiencies mentioned above; (2) the efforts by the EVS-2 ORACLES project to address aerosol-cloud-climate interactions in the SE Atlantic and (3) time permitting, recent results from a synergistic use of A-Train aerosol data to test climate model simulations of present-day direct radiative effects in some of the AEROCOM phase II global climate models.
Microdosimetry in ion-beam therapy
NASA Astrophysics Data System (ADS)
Magrin, Giulio; Mayer, Ramona
2015-06-01
The information of the dose is not sufficiently describing the biological effects of ions on tissue since it does not express the radiation quality, i.e. the heterogeneity of the processes due to the slowing-down and the fragmentation of the particles when crossing a target. Depending on different circumstances, the radiation quality can be determined using measurements, calculations, or simulations. Microdosimeters are the primary tools used to provide the experimental information of the radiation quality and their role is becoming crucial for the recent clinical developments in particular with carbon ion therapy. Microdosimetry is strongly linked to the biological effectiveness of the radiation since it provides the physical parameters which explicitly distinguish the radiation for its capability of damaging cells. In the framework of ion-beam therapy microdosimetry can be used in the preparation of the treatment to complement radiobiological experiments and to analyze the modification of the radiation quality in phantoms. A more ambitious goal is to perform the measurements during the irradiation procedure to determine the non-targeted radiation and, more importantly, to monitor the modification of the radiation quality inside the patient. These procedures provide the feedback of the treatment directly beneficial for the single patient but also for the characterization of the biological effectiveness in general with advantages for all future treatment. Traditional and innovative tools are currently under study and an outlook of present experience and future development is presented here.
Shuryak, Igor; Brenner, David J.; Ullrich, Robert L.
2011-01-01
Different types of ionizing radiation produce different dependences of cancer risk on radiation dose/dose rate. Sparsely ionizing radiation (e.g. γ-rays) generally produces linear or upwardly curving dose responses at low doses, and the risk decreases when the dose rate is reduced (direct dose rate effect). Densely ionizing radiation (e.g. neutrons) often produces downwardly curving dose responses, where the risk initially grows with dose, but eventually stabilizes or decreases. When the dose rate is reduced, the risk increases (inverse dose rate effect). These qualitative differences suggest qualitative differences in carcinogenesis mechanisms. We hypothesize that the dominant mechanism for induction of many solid cancers by sparsely ionizing radiation is initiation of stem cells to a pre-malignant state, but for densely ionizing radiation the dominant mechanism is radiation-bystander-effect mediated promotion of already pre-malignant cell clone growth. Here we present a mathematical model based on these assumptions and test it using data on the incidence of dysplastic growths and tumors in the mammary glands of mice exposed to high or low dose rates of γ-rays and neutrons, either with or without pre-treatment with the chemical carcinogen 7,12-dimethylbenz-alpha-anthracene (DMBA). The model provides a mechanistic and quantitative explanation which is consistent with the data and may provide useful insight into human carcinogenesis. PMID:22194850
NASA Astrophysics Data System (ADS)
Li, Jing; Jiang, Yiwei; Xia, Xiangao; Hu, Yongyun
2018-03-01
Previously, it was widely documented that an overall decrease in surface solar radiation occurred in China at least until 2005, in contrast to the general background of ‘global brightening’. Increased anthropogenic aerosol emissions were speculated to be the source of the reduction. In this study, we extend the trend analysis to the most recent decade from 2005-2015 and find that surface solar radiation has shifted from ‘dimming’ to ‘brightening’ over East China, with the largest increase over the northeast and southeast parts. Meanwhile, satellite and ground observation both indicate a reduction in aerosol optical depth (AOD) during the same period, whereas no significant trends in cloud amount show up. Detailed analysis using co-located radiation and aerosol observation at the XiangHe station in North China suggests that both AOD and single scattering albedo (SSA) changes contribute to the radiation trends. AOD reduction contributes to the increase of direct solar radiation, also decreasing the diffuse radiation, while the increase of SSA serves to increase the diffuse fraction. Simple calculations using a radiative transfer model confirm that the two effects combined explain changes in the global solar radiation and its components effectively. Our results have implications for potential climate effects with the reduction of China’s aerosol emissions, and the necessity to monitor aerosol composition in addition to its loading.
γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines.
Kumar, Ashok; Rai, Padmalatha S; Upadhya, Raghavendra; Vishwanatha; Prasada, K Shama; Rao, B S Satish; Satyamoorthy, Kapettu
2011-11-01
Ionizing radiation induces cellular damage through both direct and indirect mechanisms, which may include effects from epigenetic changes. The purpose of this study was to determine the effect of ionizing radiation on DNA methylation patterns that may be associated with altered gene expression. Sixteen human tumor cell lines originating from various cancers were initially tested for radiation sensitivity by irradiating them with γ-radiation in vitro and subsequently, radiation sensitive and resistant cell lines were treated with different doses of a demethylating agent, 5-Aza-2'-Deoxycytidine (5-aza-dC) and a chromatin modifier, Trichostatin-A (TSA). Survival of these cell lines was measured using 3-(4, 5-Dimethylthiazol- 2-yl)-2, 5-diphenyltetrazolium (MTT) and clonogenic assays. The effect of radiation on global DNA methylation was measured using reverse phase high performance liquid chromatography (RP-HPLC). The transcription response of methylated gene promoters, from cyclin-dependent kinase inhibitor 2A (p16(INK4a)) and ataxia telangiectasia mutated (ATM) genes, to radiation was measured using a luciferase reporter assay. γ-radiation resistant (SiHa and MDAMB453) and sensitive (SaOS2 and WM115) tumor cell lines were examined for the relationship between radiation sensitivity and DNA methylation. Treatment of cells with 5-aza-dC and TSA prior to irradiation enhanced DNA strand breaks, G2/M phase arrest, apoptosis and cell death. Exposure to γ-radiation led to global demethylation in a time-dependent manner in tumor cells in relation to resistance and sensitivity to radiation with concomitant activation of p16(INK4a) and ATM gene promoters. These results provide important information on alterations in DNA methylation as one of the determinants of radiation effects, which may be associated with altered gene expression. Our results may help in delineating the mechanisms of radiation resistance in tumor cells, which can influence diagnosis, prognosis and eventually therapy for human cancers.
Corre, Isabelle; Guillonneau, Maëva; Paris, François
2013-01-01
Tumor areas can now be very precisely delimited thanks to technical progress in imaging and ballistics. This has also led to the development of novel radiotherapy protocols, delivering higher doses of ionizing radiation directly to cancer cells. Despite this, radiation toxicity in healthy tissue remains a major issue, particularly with dose-escalation in these new protocols. Acute and late tissue damage following irradiation have both been linked to the endothelium irrigating normal tissues. The molecular mechanisms involved in the endothelial response to high doses of radiation are associated with signaling from the plasma membrane, mainly via the acid sphingomyelinase/ceramide pathway. This review describes this signaling pathway and discusses the relevance of targeting endothelial signaling to protect healthy tissues from the deleterious effects of high doses of radiation. PMID:24252908
NASA Astrophysics Data System (ADS)
Uglov, A. A.; Smurov, I. Yu; Gus'kov, A. G.; Aksenov, L. V.
1990-08-01
A theoretical study is reported of melting and thermocapillary convection under the action of laser radiation with a nonmonotonic spatial distribution of the power density. An analysis is made of changes in the geometry of the molten bath with time. The transition from a nonmonotonic boundary of a melt, corresponding to the spatial distribution of the radiation, to a monotonic one occurs in a time of the order of 1 ms when the power density of laser radiation is 105 W/cm2. The vortex structure of the flow in the molten bath is governed by the spatial distribution of the laser radiation in such a way that each local power density maximum corresponds to two vortices with oppositely directed velocity components.
Cloud Induced Enhancement of Ground Level Solar Radiation
NASA Astrophysics Data System (ADS)
Inman, R.; Chu, Y.; Coimbra, C.
2013-12-01
Atmospheric aerosol and cloud cover are typically associated with long and short-term variability of all three solar radiation components at the ground level. Although aerosol attenuation can be a substantial factor for Direct Normal Irradiance (DNI) in some microclimates, the strongest factor for ground level irradiance attenuation is cloud cover which acts on time-scales associated with strong solar power generation fluctuations. Furthermore, the driving effects of clouds on radiative energy budgets include shortwave cooling, as a result of absorption of incoming solar radiation, and longwave heating, due to reduced emission of thermal radiation by relatively cool cloud tops. Under special circumstances, the presence of clouds in the circumsolar region may lead to the reverse; a local increase in the diffuse downwelling solar radiation due to directional scattering from clouds. This solar beam effect exceed the losses resulting from the backscattering of radiation into space. Such conditions result in radiation levels that temporarily exceed the localized clear sky values. These phenomena are referred to as Cloud Enhancement Events (CEEs). There are currently two fundamental CEE mechanisms discussed in the literature. The first involves well-defined, and optically thick cloud edges close to, but not obscuring, the solar disk. The effect here is of producing little or no change in the normal beam radiation. In this case, cloud edges in the vicinity of the sun create a non-isotropic increase in the local diffuse radiation field with respect to the isotropic scattering of a clear-sky atmosphere. The second type of CEE allows for partial or full obstruction of the solar disk by an optically thin diffuser such as fine clouds, haze or fog; which results in an enhanced but still nearly isotropic diffuse radiation field. In this study, an entire year of solar radiation data and total sky images taken at 30 second resolution at the University of California, Merced (UCM) is used in conjunction with optimized clear sky models, statistical analysis, and wavelet transform methods to investigate the solar radiation Ramp Rates (RRs) associated with both of the fundamental CEE mechanisms. Results indicate that CEEs account for nearly 5% of the total daytime hours in this dataset and produce nearly 4% of the total energy over the year. In addition, wavelet transform techniques suggest that CEEs at UCM location operate on timescales ranging from 2 to 4 minutes. Our results allow estimation of the probability and magnitude of these RRs as well the percentage of annual excess energy production resulting from CEEs which could be used to offset ancillary services required to operate PV power systems.
Biological Effects of Directed Energy
NASA Astrophysics Data System (ADS)
Dayton, Thomas; Beason, Charles; Hitt, M. K.; Rogers, Walter; Cook, Michael
2002-11-01
This Final Report summarizes the biological effects research conducted by Veridian Engineering personnel under contract F41624-96-C-9009 in support of the Air Force Research Laboratory's Radio Frequency Radiation Branch from April 1997 to April 2002. Biological effects research and consultation were provided in five major areas: Active Denial System (also known as Vehicle Mounted Active Denial System), radio frequency radiation (RFR) health and safety, non-lethal weapon biological effects research, the newly formed Joint Non-Lethal Weapons Human Effects Center of Excellence, and Biotechnology. The report is organized by research efforts within the major research areas, providing title, objective, a brief description, relevance to the AF or DoD, funding, and products.
Leaf color is fine-tuned on the solar spectra to avoid strand direct solar radiation.
Kume, Atsushi; Akitsu, Tomoko; Nasahara, Kenlo Nishida
2016-07-01
The spectral distributions of light absorption rates by intact leaves are notably different from the incident solar radiation spectra, for reasons that remain elusive. Incident global radiation comprises two main components; direct radiation from the direction of the sun, and diffuse radiation, which is sunlight scattered by molecules, aerosols and clouds. Both irradiance and photon flux density spectra differ between direct and diffuse radiation in their magnitude and profile. However, most research has assumed that the spectra of photosynthetically active radiation (PAR) can be averaged, without considering the radiation classes. We used paired spectroradiometers to sample direct and diffuse solar radiation, and obtained relationships between the PAR spectra and the absorption spectra of photosynthetic pigments and organs. As monomers in solvent, the spectral absorbance of Chl a decreased with the increased spectral irradiance (W m(-2) nm(-1)) of global PAR at noon (R(2) = 0.76), and was suitable to avoid strong spectral irradiance (λmax = 480 nm) rather than absorb photon flux density (μmol m(-2) s(-1) nm(-1)) efficiently. The spectral absorption of photosystems and the intact thallus and leaves decreased linearly with the increased spectral irradiance of direct PAR at noon (I dir-max), where the wavelength was within the 450-650 nm range (R(2) = 0.81). The higher-order structure of photosystems systematically avoided the strong spectral irradiance of I dir-max. However, when whole leaves were considered, leaf anatomical structure and light scattering in leaf tissues made the leaves grey bodies for PAR and enabled high PAR use efficiency. Terrestrial green plants are fine-tuned to spectral dynamics of incident solar radiation and PAR absorption is increased in various structural hierarchies.
Radiological Protection in Medicine; OCHRONA RADIOLOGICZNA W MEDYCYNIE
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pensko, J.
1961-01-01
S>A review of radiological protection theory and systems, directed toward medical considerations is given. Examples of the types of radioactive materials and types of radiation to which humans might be exposed, the phenomena of energy loss by these types of radiation, and the effects of these transfers of energy in humans, in animals, and in matter in general, are discussed. The present limits (1961) for dose rates and exposures, under various conditions, to the several types of radiation are categorized. The shielding effects of some materials are tabulated; the data for x radiation are prevalent. Arrangement of equipment and recommendedmore » procedures for operation of x-ray devices in medical practice and diagnostic studies are described. The uses of radiation, x rays in particular, in medical therapy for various illnesses and diseases are discussed in detail. Methods of handling and disposing of radioactive wastes are presented, taking into consideration radiological protection and safety of the workers. (R.P.R.)« less
Optimised mounting conditions for poly (ether sulfone) in radiation detection.
Nakamura, Hidehito; Shirakawa, Yoshiyuki; Sato, Nobuhiro; Yamada, Tatsuya; Kitamura, Hisashi; Takahashi, Sentaro
2014-09-01
Poly (ether sulfone) (PES) is a candidate for use as a scintillation material in radiation detection. Its characteristics, such as its emission spectrum and its effective refractive index (based on the emission spectrum), directly affect the propagation of light generated to external photodetectors. It is also important to examine the presence of background radiation sources in manufactured PES. Here, we optimise the optical coupling and surface treatment of the PES, and characterise its background. Optical grease was used to enhance the optical coupling between the PES and the photodetector; absorption by the grease of short-wavelength light emitted from PES was negligible. Diffuse reflection induced by surface roughening increased the light yield for PES, despite the high effective refractive index. Background radiation derived from the PES sample and its impurities was negligible above the ambient, natural level. Overall, these results serve to optimise the mounting conditions for PES in radiation detection. Copyright © 2014 Elsevier Ltd. All rights reserved.
Active structural acoustic control of noise transmission through double panel systems
NASA Astrophysics Data System (ADS)
Carneal, James P.; Fuller, Chris R.
1995-04-01
A preliminary parametric study of active control of sound transmission through double panel systems has been experimentally performed. The technique used is the active structural acoustic control (ASAC) approach where control inputs, in the form of piezoelectric actuators, were applied to the structure while the radiated pressure field was minimized. Results indicate the application of control inputs to the radiating panel resulted in greater transmission loss due to its direct effect on the nature of the structural-acoustic coupling between the radiating panel and the receiving chamber. Increased control performance was seen in a double panel system consisting of a stiffer radiating panel with a lower modal density. As expected, more effective control of a radiating panel excited on-resonance is achieved over one excited off-resonance. In general, the results validate the ASAC approach for double panel systems and demonstrate that it is possible to take advantage of double panel behavior to enhance control performance, although it is clear that further research must be done to understand the physics involved.
NASA Technical Reports Server (NTRS)
Torres-Pomales, Wilfredo
2012-01-01
Preliminary data analysis for a physical fault injection experiment of a digital system exposed to High Intensity Radiated Fields (HIRF) in an electromagnetic reverberation chamber suggests a direct causal relation between the time profile of the field strength amplitude in the chamber and the severity of observed effects at the outputs of the radiated system. This report presents an analysis of the field strength modulation induced by the movement of the field stirrers in the reverberation chamber. The analysis is framed as a characterization of the discrete features of the field strength waveform responsible for the faults experienced by a radiated digital system. The results presented here will serve as a basis to refine the approach for a detailed analysis of HIRF-induced upsets observed during the radiation experiment. This work offers a novel perspective into the use of an electromagnetic reverberation chamber to generate upset-inducing stimuli for the study of fault effects in digital systems.
Ishikawa, Masayori; Nagase, Naomi; Matsuura, Taeko; Hiratsuka, Junichi; Suzuki, Ryusuke; Miyamoto, Naoki; Sutherland, Kenneth Lee; Fujita, Katsuhisa; Shirato, Hiroki
2015-01-01
Abstract The scintillator with optical fiber (SOF) dosimeter consists of a miniature scintillator mounted on the tip of an optical fiber. The scintillator of the current SOF dosimeter is a 1-mm diameter hemisphere. For a scintillation dosimeter coupled with an optical fiber, measurement accuracy is influenced by signals due to Cerenkov radiation in the optical fiber. We have implemented a spectral filtering technique for compensating for the Cerenkov radiation effect specifically for our plastic scintillator-based dosimeter, using a wavelength-separated counting method. A dichroic mirror was used for separating input light signals. Individual signal counting was performed for high- and low-wavelength light signals. To confirm the accuracy, measurements with various amounts of Cerenkov radiation were performed by changing the incident direction while keeping the Ir-192 source-to-dosimeter distance constant, resulting in a fluctuation of <5%. Optical fiber bending was also addressed; no bending effect was observed for our wavelength-separated SOF dosimeter. PMID:25618136
Gamma radiation effects on siloxane-based additive manufactured structures
NASA Astrophysics Data System (ADS)
Schmalzer, Andrew M.; Cady, Carl M.; Geller, Drew; Ortiz-Acosta, Denisse; Zocco, Adam T.; Stull, Jamie; Labouriau, Andrea
2017-01-01
Siloxane-basedadditive manufactured structures prepared by the direct ink write (DIW) technology were exposed to ionizing irradiation in order to gauge radiolysis effects on structure-property relationships. These well-defined 3-D structures were subjected to moderate doses of gamma irradiation in an inert atmosphere and characterized by a suite of experimental methods. Changes in thermal, chemical, microstructure, and mechanical properties were evaluated by DSC, TGA, FT-IR, mass spectroscopy, EPR, solvent swelling, SEM, and uniaxial compressive load techniques. Our results demonstrated that 3-D structures made from aromatic-free siloxane resins exhibited hardening after being exposed to gamma radiation. This effect was accompanied by gas evolution, decreasing in crystallization levels, decreasing in solvent swelling and damage to the microstructure. Furthermore, long-lived radiation-induced radicals were not detected by EPR methods. Our results are consistent with cross-link formation being the dominant degradation mechanism over chain scission reactions. On the other hand, 3-D structures made from high phenyl content siloxane resins showed little radiation damage as evidenced by low off gassing.
The effects of atmospheric cloud radiative forcing on climate
NASA Technical Reports Server (NTRS)
Randall, David A.
1989-01-01
In order to isolate the effects of atmospheric cloud radiative forcing (ACRF) on climate, the general circulation of an ocean-covered earth called 'Seaworld' was simulated using the Colorado State University GCM. Most current climate models, however, do not include an interactive ocean. The key simplifications in 'Seaworld' are the fixed boundary temperature with no land points, the lack of mountains and the zonal uniformity of the boundary conditions. Two 90-day 'perpetual July' simulations were performed and analyzed the last sixty days of each. The first run included all the model's physical parameterizations, while the second omitted the effects of clouds in both the solar and terrestrial radiation parameterizations. Fixed and identical boundary temperatures were set for the two runs, and resulted in differences revealing the direct and indirect effects of the ACRF on the large-scale circulation and the parameterized hydrologic processes.
Mundigl, Stefan
2015-04-01
With the publication of new basic safety standards for the protection against the dangers arising from exposure to ionising radiation, foreseen in Article 2 and Article 30 of the Euratom Treaty, the European Commission modernises and consolidates the European radiation protection legislation. A revision of the Basic Safety Standards was needed in order (1) to take account of the scientific and technological progress since 1996 and (2) to consolidate the existing set of Euratom radiation protection legislation, merging five Directives and upgrading a recommendation to become legally binding. The new Directive offers in a single coherent document basics safety standards for radiation protection, which take account of the most recent advances in science and technology, cover all relevant radiation sources, including natural radiation sources, integrate protection of workers, members of the public, patients and the environment, cover all exposure situations, planned, existing, emergency, and harmonise numerical values with international standards. After the publication of the Directive in the beginning of 2014, Member States have 4 y to transpose the Directive into national legislation and to implement the requirements therein. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Liu, Cong; Li, Bailong; Cheng, Ying; Lin, Jing; Hao, Jun; Zhang, Shuyu; Mitchel, R.E.J.; Sun, Ding; Ni, Jin; Zhao, Luqian; Gao, Fu; Cai, Jianming
2011-01-01
Dysregulation of certain microRNAs (miRNAs) in cancer can promote tumorigenesis, metastasis and invasion. However, the functions and targets of only a few mammalian miRNAs are known. In particular, the miRNAs that participates in radiation induced carcinogenesis and the miRNAs that target the tumor suppressor gene Big-h3 remain undefined. Here in this study, using a radiation induced thymic lymphoma model in BALB/c mice, we found that the tumor suppressor gene Big-h3 is down-regulated and miR-21 is up-regulated in radiation induced thymic lymphoma tissue samples. We also found inverse correlations between Big-h3 protein and miR-21 expression level among different tissue samples. Furthermore, our data indicated that miR-21 could directly target Big-h3 in a 3′UTR dependent manner. Finally, we found that miR-21 could be induced by TGFβ, and miR-21 has both positive and negative effects in regulating TGFβ signaling. We conclude that miR-21 participates in radiation induced carcinogenesis and it regulates TGFβ signaling. PMID:21494432
NASA Astrophysics Data System (ADS)
Lewinschal, A.; Ekman, A. M. L.; Körnich, H.
2012-04-01
Aerosol particles have a considerable impact on the energy budget of the atmosphere due to their ability to scatter and absorb incoming solar radiation. Persistent particle emissions in certain regions of the world have lead to quasi-permanent aerosol forcing patterns. This spatially varying forcing pattern has the potential to modify temperature gradients that in turn alter pressure gradients and the atmospheric circulation. This study focuses on the effect of aerosol direct radiative forcing on northern hemisphere wintertime stationary waves. A global general circulation model based on the ECMWF operational forecast model is applied (EC-Earth). Aerosols are prescribed as monthly mean mixing ratios of sulphate, black carbon, organic carbon, dust and sea salt. Only the direct aerosol effect is considered. The climatic change is defined as the difference between model simulations using present-day and pre-industrial concentrations of aerosol particles. Data from 40-year long simulations using a coupled ocean-atmosphere model system are used. In EC-Earth, the high aerosol loading over South Asia leads to a surface cooling, which appears to enhance the South Asian winter monsoon and weaken the Indian Ocean Walker circulation. The anomalous Walker circulation leads to changes in tropical convective precipitation and consequent changes in latent heat release which effectively acts to generate planetary scale waves propagating into the extra-tropics. Using a steady-state linear model we verify that the aerosol-induced anomalous convective precipitation is a crucial link between the wave changes and the direct aerosol radiative forcing.
Radiogenic cell transformation and carcinogenesis
NASA Technical Reports Server (NTRS)
Yang, T. C.; Georgy, K. A.; Mei, M.; Durante, M.; Craise, L. M.
1995-01-01
Radiation carcinogenesis is one of the major biological effects considered important in the risk assessment for space travel. Various biological model systems, including both cultured cells and animals, have been found useful for studying the carcinogenic effects of space radiations, which consist of energetic electrons, protons and heavy ions. The development of techniques for studying neoplastic cell transformation in culture has made it possible to examine the cellular and molecular mechanisms of radiation carcinogenesis. Cultured cell systems are thus complementary to animal models. Many investigators have determined the oncogenic effects of ionizing and nonionizing radiation in cultured mammalian cells. One of the cell systems used most often for radiation transformation studies is mouse embryonic cells (C3H10T1/2), which are easy to culture and give good quantitative dose-response curves. Relative biological effectiveness (RBE) for heavy ions with various energies and linear energy transfer (LET) have been obtained with this cell system. Similar RBE and LET relationship was observed by investigators for other cell systems. In addition to RBE measurements, fundamental questions on repair of sub- and potential oncogenic lesions, direct and indirect effect, primary target and lesion, the importance of cell-cell interaction and the role of oncogenes and tumor suppressor genes in radiogenic carcinogenesis have been studied, and interesting results have been found. Recently several human epithelial cell systems have been developed, and ionizing radiation have been shown to transform these cells. Oncogenic transformation of these cells, however, requires a long expression time and/or multiple radiation exposures. Limited experimental data indicate high-LET heavy ions can be more effective than low-LET radiation in inducing cell transformation. Cytogenetic and molecular analyses can be performed with cloned transformants to provide insights into basic genetic mechanism(s) of radiogenic transformation of human epithelial cells.
Liu, Xiuwei; Sun, Hongyong; Feike, Til; Zhang, Xiying; Shao, Liwei; Chen, Suying
2016-01-01
The major wheat production region of China the North China Plain (NCP) is seriously affected by air pollution. In this study, yield of winter wheat (Triticum aestivum L.) was analyzed with respect to the potential impact of air pollution index under conditions of optimal crop management in the NCP from 2001 to 2012. Results showed that air pollution was especially serious at the early phase of winter wheat growth significantly influencing various weather factors. However, no significant correlations were found between final grain yield and the weather factors during the early growth phase. In contrast, significant correlations were found between grain yield and total solar radiation gap, sunshine hour gap, diurnal temperature range and relative humidity during the late growing phase. To disentangle the confounding effects of various weather factors, and test the isolated effect of air pollution induced changes in incoming global solar radiation on yield under ceteris paribus conditions, crop model based scenario-analysis was conducted. The simulation results of the calibrated Agricultural Production Systems Simulator (APSIM) model indicated that a reduction in radiation by 10% might cause a yield reduction by more than 10%. Increasing incident radiation by 10% would lead to yield increases of (only) 7%, with the effects being much stronger during the late growing phase compared to the early growing phase. However, there is evidence that APSIM overestimates the effect of air pollution induced changes on radiation, as it does not consider the changes in radiative properties of solar insulation, i.e. the relative increase of diffuse over direct radiation, which may partly alleviate the negative effects of reduced total radiation by air pollution. Concluding, the present study could not detect a significantly negative effect of air pollution on wheat yields in the NCP.
Spectral radiation analyses of the GOES solar illuminated hexagonal cell scan mirror back
NASA Technical Reports Server (NTRS)
Fantano, Louis G.
1993-01-01
A ray tracing analytical tool has been developed for the simulation of spectral radiation exchange in complex systems. Algorithms are used to account for heat source spectral energy, surface directional radiation properties, and surface spectral absorptivity properties. This tool has been used to calculate the effective solar absorptivity of the geostationary operational environmental satellites (GOES) scan mirror in the calibration position. The development and design of Sounder and Imager instruments on board GOES is reviewed and the problem of calculating the effective solar absorptivity associated with the GOES hexagonal cell configuration is presented. The analytical methodology based on the Monte Carlo ray tracing technique is described and results are presented and verified by experimental measurements for selected solar incidence angles.
Radiation-Spray Coupling for Realistic Flow Configurations
NASA Technical Reports Server (NTRS)
El-Asrag, Hossam; Iannetti, Anthony C.
2011-01-01
Three Large Eddy Simulations (LES) for a lean-direct injection (LDI) combustor are performed and compared. In addition to the cold flow simulation, the effect of radiation coupling with the multi-physics reactive flow is analyzed. The flame let progress variable approach is used as a subgrid combustion model combined with a stochastic subgrid model for spray atomization and an optically thin radiation model. For accurate chemistry modeling, a detailed Jet-A surrogate mechanism is utilized. To achieve realistic inflow, a simple recycling technique is performed at the inflow section upstream of the swirler. Good comparison is shown with the experimental data mean and root mean square profiles. The effect of combustion is found to change the shape and size of the central recirculation zone. Radiation is found to change the spray dynamics and atomization by changing the heat release distribution and the local temperature values impacting the evaporation process. The simulation with radiation modeling shows wider range of droplet size distribution by altering the evaporation rate. The current study proves the importance of radiation modeling for accurate prediction in realistic spray combustion configurations, even for low pressure systems.
NASA Astrophysics Data System (ADS)
Reidenbach, Hans-Dieter
Safety considerations in the field of laser radiation have traditionally been restricted to maximum permissible exposure levels defined as a function of wavelength and exposure duration. But in Europe according to the European Directive 2006/25/EC on artificial optical radiation the employer has to include in his risk assessment indirect effects from temporary blinding. Whereas sufficient knowledge on various deterministic risks exists, only sparse quantitative data is available for the impairment of visual functions due to temporary blinding from visible optical radiation. The consideration of indirect effects corresponds to a paradigm change in risk assessment when situations have to be treated, where intrabeam viewing of low-power laser radiation is likely or other non-coherent visible radiation might influence certain visual tasks. In order to obtain a sufficient basis for the assessment of certain situations, investigations of the functional relationships between wavelength, exposure time and optical power and the resulting interference on visual functions have been performed and the results are reported. The duration of a visual disturbance is thus predictable. In addition, preliminary information on protective measures is given.
NASA Technical Reports Server (NTRS)
Nessel, James A.; Simons, Rainee N.; Miranda, Felix A.
2007-01-01
The near field radiation characteristics of implantable Square Spiral Chip Inductor Antennas (SSCIA) for Bio-Sensors have been measured. Our results indicate that the measured near field relative signal strength of these antennas agrees with simulated results and confirm that in the near field region the radiation field is fairly uniform in all directions. The effects of parameters such as ground-plane, number of turns and microstrip-gap width on the performance of the SSCIA are presented. Furthermore, the SSCIA antenna with serrated ground plane produce a broad radiation pattern, with a relative signal strength detectable at distances within the range of operation of hand-held devices for self-diagnosis.
Spatially Refined Aerosol Direct Radiative Focusing Efficiencies
Global aerosol direct radiative forcing (DRF) is an important metric for assessing potential climate impacts of future emissions changes. However, the radiative consequences of emissions perturbations are not readily quantified nor well understood at the level of detail necessary...
Spatially Refined Aerosol Direct Radiative Forcing Efficiencies
Global aerosol direct radiative forcing (DRF) is an important metric for assessing potential climate impacts of future emissions changes. However, the radiative consequences of emissions perturbations are not readily quantified nor well understood at the level of detail necessary...
The Key Factors Analysis of Palisades Temperature in Deep Open-pit Mine
NASA Astrophysics Data System (ADS)
Wang, Yuan; Du, Cuifeng; Jin, Wenbo; Wang, Puyu
2018-01-01
In order to study the key factors of palisades temperature field in a deep open-pit mine in the natural environment, the influence of natural factors on the palisades temperature in a deep open-pit mine were analysed based on the principle of heat transfer. Four typical places with different ways of solar radiation were selected to carry out the field test. The results show that solar radiation, atmospheric temperature, and wind speed are three main factors affecting the temperature of palisades and that the direct sunlight plays a leading role. The time period of the sun shining directly on the shady slope of the palisades is short because of blocking effect, whose temperature changes in a smaller scale. At the same time, the sun slope of the palisades suffers from the solar radiation for a long time, whose temperature changes in a larger scale, and the variation is similar to the air temperature.
Development of indirect EFBEM for radiating noise analysis including underwater problems
NASA Astrophysics Data System (ADS)
Kwon, Hyun-Wung; Hong, Suk-Yoon; Song, Jee-Hun
2013-09-01
For the analysis of radiating noise problems in medium-to-high frequency ranges, the Energy Flow Boundary Element Method (EFBEM) was developed. EFBEM is the analysis technique that applies the Boundary Element Method (BEM) to Energy Flow Analysis (EFA). The fundamental solutions representing spherical wave property for radiating noise problems in open field and considering the free surface effect in underwater are developed. Also the directivity factor is developed to express wave's directivity patterns in medium-to-high frequency ranges. Indirect EFBEM by using fundamental solutions and fictitious source was applied to open field and underwater noise problems successfully. Through numerical applications, the acoustic energy density distributions due to vibration of a simple plate model and a sphere model were compared with those of commercial code, and the comparison showed good agreement in the level and pattern of the energy density distributions.
High-Q silica zipper cavity for optical radiation pressure driven MOMS switch
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tetsumoto, Tomohiro; Tanabe, Takasumi, E-mail: takasumi@elec.keio.ac.jp
2014-07-15
We design a silica zipper cavity that has high optical and mechanical Q (quality factor) values and demonstrate numerically the feasibility of a radiation pressure driven micro opto-mechanical system (MOMS) directional switch. The silica zipper cavity has an optical Q of 4.0 × 10{sup 4} and an effective mode volume V{sub mode} of 0.67λ{sup 3} when the gap between two cavities is 34 nm. The mechanical Q (Q{sub m}) is determined by thermo-elastic damping and is 2.0 × 10{sup 6} in a vacuum at room temperature. The opto-mechanical coupling rate g{sub OM} is as high as 100 GHz/nm, which allowsmore » us to move the directional cavity-waveguide system and switch 1550-nm light with 770-nm light by controlling the radiation pressure.« less
UV spectral irradiance measurements in New Zealand: Effects of Pinatubo volcanic aerosol
NASA Technical Reports Server (NTRS)
Mckenzie, Richard L.
1994-01-01
Since late 1989, regular UV spectral irradiance measurements have been made at Lauder, New Zealand (45 deg S, 170 deg E), whenever weather permits. Here, the instrumentation and measurement strategy are outlined, and early results are discussed. Following the eruption of Mt Pinatubo in June 1991, large amounts of volcanic aerosol were injected into the stratosphere and were subsequently transported to New Zealand's latitudes in the latter half of 1991. This provides an opportunity to investigate the effects of volcanic aerosols on UV irradiances measured at this clean-air site. Although changes in global (sum of diffuse plus direct) irradiances were below the detection threshold, there were significant changes in the partitioning of radiation between the direct beam and diffuse skylight. Decreases by nearly a factor of two in the direct/diffuse ratio were observed at longer wavelengths, and at smaller solar zenith angles (sza's). The aerosol optical depth due to volcanic aerosol over Lauder in December 1991 was 0.15 plus or minus 0.02 at 450 nm, with lower values at shorter wavelengths. Although effects were relatively small in the UVB region, an implication of the changes is that the contrast between shade and direct sun is reduced, so that shaded areas received relatively more radiation in the summer of 1991/92 in New Zealand.
The Response of the Ocean Thermal Skin Layer to Air-Sea Surface Heat Fluxes
NASA Astrophysics Data System (ADS)
Wong, Elizabeth Wing-See
There is much evidence that the ocean is heating as a result of an increase in concentrations of greenhouse gases (GHGs) in the atmosphere from human activities. GHGs absorb infrared radiation and re-emit infrared radiation back to the ocean's surface which is subsequently absorbed. However, the incoming infrared radiation is absorbed within the top micrometers of the ocean's surface which is where the thermal skin layer exists. Thus the incident infrared radiation does not directly heat the upper few meters of the ocean. We are therefore motivated to investigate the physical mechanism between the absorption of infrared radiation and its effect on heat transfer at the air-sea boundary. The hypothesis is that since heat lost through the air-sea interface is controlled by the thermal skin layer, which is directly influenced by the absorption and emission of infrared radiation, the heat flow through the thermal skin layer adjusts to maintain the surface heat loss, assuming the surface heat loss does not vary, and thus modulates the upper ocean heat content. This hypothesis is investigated through utilizing clouds to represent an increase in incoming longwave radiation and analyzing retrieved thermal skin layer vertical temperature profiles from a shipboard infrared spectrometer from two research cruises. The data are limited to night-time, no precipitation and low winds of less than 2 m/s to remove effects of solar radiation, wind-driven shear and possibilities of thermal skin layer disruption. The results show independence of the turbulent fluxes and emitted radiation on the incident radiative fluxes which rules out the immediate release of heat from the absorption of the cloud infrared irradiance back into the atmosphere through processes such as evaporation and increase infrared emission. Furthermore, independence was confirmed between the incoming and outgoing radiative flux which implies the heat sink for upward flowing heat at the air-sea interface is more-or-less fixed. The surplus energy, from absorbing increasing levels of infrared radiation, is found to adjust the curvature of the thermal skin layer such that there is a smaller gradient at the interface between the thermal skin layer and the mixed layer beneath. The vertical conduction of heat from the mixed layer to the surface is therefore hindered while the additional energy within the thermal skin layer is supporting the gradient changes of the skin layer's temperature profile. This results in heat beneath the thermal skin layer, which is a product of the absorption of solar radiation during the day, to be retained and cause an increase in upper ocean heat content. The accuracy of four published skin layer models were evaluated by comparison with the field results. The results show a need to include radiative effects, which are currently absent, in such models as they do not replicate the findings from the field data and do not elucidate the effects of the absorption of infrared radiation.
Miao, Lu; Holley, Aaron K.; Zhao, Yanming; St. Clair, William H.
2014-01-01
Abstract Significance: Radiation therapy is widely used for treatment of prostate cancer. Radiation can directly damage biologically important molecules; however, most effects of radiation-mediated cell killing are derived from the generated free radicals that alter cellular redox status. Multiple proinflammatory mediators can also influence redox status in irradiated cells and the surrounding microenvironment, thereby affecting prostate cancer progression and radiotherapy efficiency. Recent Advances: Ionizing radiation (IR)–generated oxidative stress can regulate and be regulated by the production of proinflammatory mediators. Depending on the type and stage of the prostate cancer cells, these proinflammatory mediators may lead to different biological consequences ranging from cell death to development of radioresistance. Critical Issues: Tumors are heterogeneous and dynamic communication occurs between stromal and prostate cancer cells, and complicated redox-regulated mechanisms exist in the tumor microenvironment. Thus, antioxidant and anti-inflammatory strategies should be carefully evaluated for each patient at different stages of the disease to maximize therapeutic benefits while minimizing unintended side effects. Future Directions: Compared with normal cells, tumor cells are usually under higher oxidative stress and secrete more proinflammatory mediators. Thus, redox status is often less adaptive in tumor cells than in their normal counterparts. This difference can be exploited in a search for new cancer therapeutics and treatment regimes that selectively activate cell death pathways in tumor cells with minimal unintended consequences in terms of chemo- and radio-resistance in tumor cells and toxicity in normal tissues. Antioxid. Redox Signal. 20, 1481–1500. PMID:24093432
Protective effect of rare earth against oxidative stress under ultraviolet-B radiation.
Wang, Lihong; Huang, Xiaohua; Zhou, Qing
2009-04-01
The effects of lanthanum (III) (La(III)) in protecting soybean leaves against oxidative stress induced by ultraviolet-B (UV-B) radiation were investigated. The increase in contents of hydrogen peroxide (H(2)O(2)) and superoxide (O2*-) due to UV-B radiation suggested oxidative stress. The increase in the content of malondialdehyde (MDA) and the decrease in the index of unsaturated fatty acid (IUFA) indicated oxidative damage on cell membrane induced by UV-B radiation. La(III) partially reversed UV-B-radiation-induced damage of plant growth. The reduction in the contents of H(2)O(2), O2*-, and MDA and increase in the content of IUFA, compared with UV-B treatment, also indicated that La(III) alleviated the oxidative damage induced by UV-B radiation. The increase in the activities of superoxide dismutase and peroxidase and the contents of ascorbate, carotenoids, and flavonoids were observed in soybean leaves with La(III) + UV-B treatment, compared with UV-B treatment. Our data suggested that La(III) could protect soybean plants from UV-B-radiation-induced oxidative stress by reacting with reactive oxygen species directly or by improving the defense system of plants.
Role of connexin43 and ATP in long-range bystander radiation damage and oncogenesis in vivo.
Mancuso, M; Pasquali, E; Leonardi, S; Rebessi, S; Tanori, M; Giardullo, P; Borra, F; Pazzaglia, S; Naus, C C; Di Majo, V; Saran, A
2011-11-10
Ionizing radiation is a genotoxic agent and human carcinogen. Recent work has questioned long-held dogmas by showing that cancer-associated genetic alterations occur in cells and tissues not directly exposed to radiation, questioning the robustness of the current system of radiation risk assessment. In vitro, diverse mechanisms involving secreted soluble factors, gap junction intercellular communication (GJIC) and oxidative metabolism are proposed to mediate these indirect effects. In vivo, the mechanisms behind long-range 'bystander' responses remain largely unknown. Here, we investigate the role of GJIC in propagating radiation stress signals in vivo, and in mediating radiation-associated bystander tumorigenesis in mouse central nervous system using a mouse model in which intercellular communication is downregulated by targeted deletion of the connexin43 (Cx43) gene. We show that GJIC is critical for transmission of oncogenic radiation damage to the non-targeted cerebellum, and that a mechanism involving adenosine triphosphate release and upregulation of Cx43, the major GJIC constituent, regulates transduction of oncogenic damage to unirradiated tissues in vivo. Our data provide a novel hypothesis for transduction of distant bystander effects and suggest that the highly branched nervous system, similar to the vascular network, has an important role.
Biological effectiveness of neutrons: Research needs
NASA Astrophysics Data System (ADS)
Casarett, G. W.; Braby, L. A.; Broerse, J. J.; Elkind, M. M.; Goodhead, D. T.; Oleinick, N. L.
1994-02-01
The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy.