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Sample records for directive priority substances

  1. Recent Trends in Monitoring of European Water Framework Directive Priority Substances Using Micro-Sensors: A 2007–2009 Review

    PubMed Central

    Namour, Philippe; Lepot, Mathieu; Jaffrezic-Renault, Nicole

    2010-01-01

    This review discusses from a critical perspective the development of new sensors for the measurement of priority pollutants targeted in the E.U. Water Framework Directive. Significant advances are reported in the paper and their advantages and limitations are also discussed. Future perspectives in this area are also pointed out in the conclusions. This review covers publications appeared since December 2006 (the publication date of the Swift report). Among priority substances, sensors for monitoring the four WFD metals represent 81% of published papers. None of analyzed publications present a micro-sensor totally validated in laboratory, ready for tests under real conditions in the field. The researches are mainly focused on the sensing part of the micro-sensors. Nevertheless, the main factor limiting micro-sensor applications in the environment is the ruggedness of the receptor towards environmental conditions. This point constitutes the first technological obstacle to be overcome for any long-term field tests. PMID:22163635

  2. EU Water Framework Directive and Stockholm Convention: can we reach the targets for priority substances and persistent organic pollutants?

    PubMed

    Fuerhacker, Maria

    2009-08-01

    place as the main European legislation to protect our water resources and the water environment of Europe since 2000. It requires managing river basins so that the quality and quantity of water does not affect the ecological services of any specific water body. Nevertheless, the goals of other directives as for drinking water, bathing water and urban wastewater treatment are not yet harmonised mainly concerning microbiological, priority substances and priority hazardous substances (PS/PHS) contamination. Following the detection of substances, a risk assessment with sound effect data needs to be performed also for regulatory decisions and priorisation of measures to remove emerging contaminants. Beside personal care products and industrial contaminants, faecal pollution of recreational waters is one of the major hazards facing users, although microbial contamination from other sources as well as chemical and physical aspects also affects the suitability of water for recreation. As in arid and semiarid areas, wastewater is considered for irrigation with regulatory needs of hygienic and chemical parameters-health-based targets-to avoid the contamination of crops and food. In surface waters, currently, the relationships between physical and chemical properties and the biological state of surface waters were quite well-understood to enable the management of catchments and rivers to achieve ecological quality. Nevertheless, more work is needed to find out the actual impact of the regulations for single chemicals and complex mixtures, in terms of environmental quality standards to achieve a 'good chemical status', on the good biological status. In a next step after the adoption of the list of PS/PHS substances, which also includes the POPs, the Urban Wastewater Treatment Directive (UWWTD) needs to be adjusted and existing or new treatment options (BATs) should comply with the new requirements of the different directives. Relevant substances threaten human health and the

  3. Determination of the priority substances regulated by 2000/60/EC and 2008/105/EC Directives in the surface waters supplying water treatment plants of Athens, Greece.

    PubMed

    Golfinopoulos, Spyros K; Nikolaou, Anastasia D; Thomaidis, Nikolaos S; Kotrikla, Anna Maria; Vagi, Maria C; Petsas, Andreas S; Lekkas, Demetris F; Lekkas, Themistokles D

    2017-03-21

    An investigation into the occurrence of priority substances regulated by 2000/60/EC Water Framework Directive and 2008/105/EC Directive was conducted for a period of one year in the surface water sources supplying the water treatment plants (WTPs) of Athens and in the raw water of WTPs. Samples from four reservoirs and four water treatment plants of Athens were taken seasonally. The substances are divided into seven specific groups, including eight volatile organic compounds (VOCs), diethylhexylphthalate, four organochlorine pesticides (OCPs), three organophosphorus/organonitrogen pesticides (OPPs/ONPs), four triazines and phenylurea herbicides, pentachlorophenol, and four metals. The aforementioned substances belong to different chemical categories, and different analytical methods were performed for their determination. The results showed that the surface waters that feed the WTPs of Athens are not burdened with significant levels of toxic substances identified as European Union (EU) priority substances. Atrazine, hexachlorocyclohexane, endosulfan, trifluralin, anthracene and 4-nonylphenol were occasionally observed at very low concentrations. Their presence in a limited number of cases could be attributed to waste disposal, agricultural activities, and to a limited industrial activity in the area nearby the water bodies.

  4. Current levels and trends of selected EU Water Framework Directive priority substances in freshwater fish from the German environmental specimen bank.

    PubMed

    Fliedner, Annette; Lohmann, Nina; Rüdel, Heinz; Teubner, Diana; Wellmitz, Jörg; Koschorreck, Jan

    2016-09-01

    Under the German environmental specimen bank programme bream (Abramis brama) were sampled in six German rivers and analysed for the priority hazardous substances dicofol, hexabromocyclododecane (HBCDD), hexachlorobenzene (HCB), hexachlorobutadiene (HCBD), heptachlor + heptachlor epoxide (HC + HCE), polybrominated diphenylethers (PBDEs), polychlorinated dibenzo-p-dioxins and -furans and dioxin-like polychlorinated biphenyls (PCDD/Fs + dl-PCBs), and perfluorooctane sulfonic acid (PFOS). The aim was to assess compliance with the EU Water Framework Directive environmental quality standards for biota (EQSBiota) for the year 2013, and to analyse temporal trends for those substances that are of special concern. General compliance was observed for dicofol, HBCDD and HCBD whereas PBDEs exceeded the EQSBiota at all sites. For all other substances compliance in 2013 varied between locations. No assessment was possible for HC + HCE at some sites where the analytical sensitivity was not sufficient to cover the EQSBiota. Trend analysis showed decreasing linear trends for HCB and PFOS at most sampling sites between 1995 and 2014 indicating that the emission reduction measures are effective. Mostly decreasing trends or constant levels were also observed for PCDD/Fs and dl-PCBs. In contrast, increasing trends were detected for PBDEs and HBCDD which were especially pronounced at one Saar site located downstream of the industries and conurbation of Saarbrücken and Völklingen. This finding points to new sources of emissions which should be followed in the coming years.

  5. New priority substances of the European Water Framework Directive: biocides, pesticides and brominated flame retardants in the aquatic environment of Denmark.

    PubMed

    Vorkamp, Katrin; Bossi, Rossana; Bester, Kai; Bollmann, Ulla E; Boutrup, Susanne

    2014-02-01

    The biocides cybutryn (Irgarol) and terbutryn, the herbicides aclonifen and bifenox, the insecticides cypermethrin and heptachlor/heptachlor epoxide and the brominated flame retardant hexabromocyclododecane (HBCD) are new priority substances of the Water Framework Directive of the European Union. In order to gain knowledge about their presence in the aquatic environment in an off-season situation with regard to pesticide and biocide applications, these substances were analysed in freshwater, seawater and fish samples from Denmark. Aclonifen, bifenox, cypermethrin and heptachlor were below the limits of detection (LODs) in all samples. However, the LODs for cypermethrin and heptachlor exceeded the annual average environmental quality standards (AA-EQSs). Cybutryn, terbutryn, heptachlor epoxide and HBCD were detected in the majority of samples, with detection frequencies of 100% for heptachlor epoxide and HBCD in water and 90% in fish. No concentration was above maximum allowable concentration (MAC)-EQS values, but AA-EQS values were exceeded for all four compounds by several samples, including 100% of the water samples with regard to heptachlor epoxide. Methodological issues remain for cypermethrin, and to a certain extent for heptachlor/heptachlor epoxide, for which water LODs were above AA-EQSs although a water volume of 12L was combined with very sensitive high resolution mass spectrometry. © 2013.

  6. Multiresidue analysis of 24 Water Framework Directive priority substances by on-line solid phase extraction-liquid chromatography tandem mass spectrometry in environmental waters.

    PubMed

    Rubirola, Adrià; Boleda, Mª Rosa; Galceran, Mª Teresa

    2017-04-14

    This paper reports the development of a fully multiresidue and automated on-line solid phase extraction (SPE) - liquid chromatography tandem mass spectrometry (LC-MS/MS) method for the determination of 24 priority substances (PS) belonging to different classes (pesticides, hormones or pharmaceuticals) included in the Directive 2013/39/UE and the recent Watch List (Decision 2015/495) in water samples (drinking water, surface water, and effluent wastewaters). LC-MS/MS conditions and on-line SPE parameters such as sorbent type, sample and wash volumes were optimized. The developed method is highly sensitive (limits of detection between 0.1 and 1.4ngL(-1)) and precise (relative standard deviations lower than 8%). As part of the method validation studies, linearity, accuracy and matrix effects were assessed. The main advantage of this method over traditional off-line procedures is the minimization of tedious sample preparation increasing productivity and sample throughput. The optimized method was applied to the analysis of water samples and the results revealed the presence of 16 PS in river water and effluent water of wastewater treatment plants.

  7. The hazardous priority substances in Italy: National rules and environmental quality standard in marine environment

    SciTech Connect

    Maggi, Chiara Onorati, Fulvio Lamberti, Claudia Virno Cicero, Anna Maria

    2008-01-15

    Article number 16 of the Water Framework Directive (Directive 2000/60/EC) lays down the community strategy for establishment of harmonised quality standards for the priority substances and other substances posing a significant risk to the aquatic environment. In order to achieve the protection objectives of the Directive 2000/60/EC, the Italian Ministry of the Environment proposed the quality standards for surface water, sediments and biota related to the priority substances listed in the decision No. 2455/2001/EC of the European Parliament and of the Council of November 20 (2001) [Decision N. 2455/2001/EC of the European Parliament and of the Council of 20 November 2001. The list of priority substances in the field of water policy and amending Directive 2000/60/EC. Official Journal of the European Communities, 15.12.2001, p. 5]. Particularly, for the protection of the marine environment, the proposed Italian rules state that, from 1 January 2021, the concentrations of the hazardous priority substances in Italian marine and lagoon waters must be near the natural background for natural substances, like metals, and near zero for the anthropogenic one. According to Directive 2000/60/EC, the Italian Ministry of Environment issued in 2003 Decree 367 in which has derived 160 Environmental Quality Standard (EQS) for water and 27 Environmental Quality Objective (EQO) for sediment of marine coastal area, lagoons and coastal ponds. Biota quality standards have still to be fixed. The paper illustrates the criteria applied for the definition of the quality standards and some comments are presented.

  8. Development of computerized scenarios for wildlife exposure to priority substances

    SciTech Connect

    Brownlee, L.J.; McPherson, S.M.; Norton, M.R.; Ward, D.R.; Lloyd, K.M.

    1995-12-31

    A computerized model has been developed to estimate wildlife exposure in the Canadian environment to substances through inhalation and ingestion of food, water and soil. This Windows application was developed in Visual Basic using Microsoft Access databases and designed to make the evaluation process consistent, transparent and efficient. Bird, mammal, amphibian and reptile species were selected on the basis of food guild, body size, habitat and distribution in Canada. Intake rates were estimated using allometric equations or measured intake rates when available. Ingestion rates were estimated from free-living metabolic rates and dietary composition. With the information, the authors will develop the exposure scenarios required for assessments of risk to wildlife from priority substances listed in the Canadian Environmental Protection Act.

  9. Multi-residue analysis and ultra-trace quantification of 36 priority substances from the European Water Framework Directive by GC-MS and LC-FLD-MS/MS in surface waters.

    PubMed

    Barrek, Sami; Cren-Olivé, Cécile; Wiest, Laure; Baudot, Robert; Arnaudguilhem, Carine; Grenier-Loustalot, Marie-Florence

    2009-08-15

    A multi residue analysis was developed for screening, quantification and confirmation of 36 priority organic compounds included in the 2000/60/EC European Water Framework Directive. The compounds analyzed included 19 pesticides, 8 PAH, 5 endocrine-disruptors and 4 organochlorine compounds. The method was developed in three steps. First, automated off-line solid-phase extraction using Strata X cartridges was optimized to trap simultaneously the 36 studied compounds. Second, the more volatile compounds were analysed by gas chromatography coupled to mass spectrometry with electron impact ionisation in selected ion monitoring mode (SIM). Third, the last 20 compounds were detected and quantified, in one run, by liquid chromatography coupled to fluorescence detector and tandem mass spectrometry. The excellent selectivity and sensitivity allowed us satisfactory quantification and confirmation at levels as low as 0.2-67 ng L(-1) with recoveries between 59 and 105%. Such methodology was then applied to French surface waters: all the waters present organic contaminants, and their concentration varied according to the origin and nature of substances.

  10. Presence of selected priority and personal care substances in an onsite bathroom greywater treatment facility.

    PubMed

    Eriksson, E; Donner, E; Ledin, A

    2010-01-01

    In recent years, concerns about climate change and the inefficient use and ongoing pollution of water resources have increased the political motivation to encourage water recycling. This has led to the widespread introduction of water saving measures and to advances in the decentralised treatment and reuse of wastewater. In particular, the treatment and reuse of greywater has received attention, although important information such as greywater substance loadings is still only rarely available. With the implementation of the European Water Framework Directive the focus on controlling and phasing-out Priority/Priority Hazardous Substances (PS/PHS) is growing, and it is vital to know their sources and flows in order to generate sustainable emission control strategies. The main objective of this study was to quantify the concentrations and loads of PS/PHS and personal care substances in bathroom greywater, and to thereby assess the contribution of household activities to municipal wastewater loads for these substances. Nickel and mercury may be sourced substantially from household activities as it shown in the paper that bathroom greywater contributed a significant proportion of the overall load of these substances at the municipal wastewater treatment plant. Organic matter in the influent greywater was found to be principally associated with large particles (>8 µm), however it was the dissolved and small sized particles that were predominantly removed in the treatment.

  11. Presence and fate of priority substances in domestic greywater treatment and reuse systems.

    PubMed

    Donner, E; Eriksson, E; Revitt, D M; Scholes, L; Lützhøft, H-C Holten; Ledin, A

    2010-05-15

    A wide range of household sources may potentially contribute to contaminant loads in domestic greywater. The ability of greywater treatment systems to act as emission control barriers for household micropollutants, thereby providing environmental benefits in addition to potable water savings, have not been fully explored. This paper investigates the sources, presence and potential fate of a selection of xenobiotic micropollutants in on-site greywater treatment systems. All of the investigated compounds are listed under the European Water Framework Directive as either "Priority Substances" (PS) or "Priority Hazardous Substances" (PHS). Significant knowledge gaps are identified. A wide range of potential treatment trains are available for greywater treatment and reuse but treatment efficiency data for priority substances and other micropollutants is very limited. Geochemical modelling indicates that PS/PHS removal during treatment is likely to be predominantly due to sludge/solid phase adsorption, with only minor contributions to the water phase. Many PS/PHS are resistant to biodegradation and as the majority of automated greywater treatment plants periodically discharge sludge to the municipal sewerage system, greywater treatment is unlikely to act as a comprehensive PS/PHS emission barrier. Hence, it is important to ensure that other source control options (e.g. eco-labeling, substance substitution, and regulatory controls) for household items continue to be pursued, in order that PS/PHS emissions from these sources are effectively reduced and/or phased out as required under the demands of the European Water Framework Directive. Copyright 2010 Elsevier B.V. All rights reserved.

  12. 75 FR 56015 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List: Partial Deletion of the Letterkenny Army Depot Southeastern (SE) Area and Letterkenny...

  13. 75 FR 44932 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ...; FRL-9183-1] National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List... substances, Intergovernmental relations, Natural resources, Oil pollution, Penalties, Reporting and..., Compensation, and Liability Act (CERCLA) of 1980, is an Appendix of the National Oil and Hazardous...

  14. 77 FR 46009 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-02

    ...-; FRL-9704-3] National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List... National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of Maine... all Site media (including soil and groundwater). DATES: Comments must be received by September 4,...

  15. Priority Substances and Emerging Organic Pollutants in Portuguese Aquatic Environment: A Review.

    PubMed

    Ribeiro, Cláudia; Ribeiro, Ana Rita; Tiritan, Maria Elizabeth

    Aquatic environments are among the most noteworthy ecosystems regarding chemical pollution due to the anthropogenic pressure. In 2000, the European Commission implemented the Water Framework Directive, with the aim of progressively reducing aquatic chemical pollution of the European Union countries. Therefore, the knowledge about the chemical and ecological status is imperative to determine the overall quality of water bodies. Concerning Portugal, some studies have demonstrated the presence of pollutants in the aquatic environment but an overall report is not available yet. The aim of this paper is to provide a comprehensive review about the occurrence of priority substances included in the Water Framework Directive and some classes of emerging organic pollutants that have been found in Portuguese aquatic environment. The most frequently studied compounds comprise industrial compounds, natural and synthetic estrogens, phytoestrogens, phytosterols, pesticides, pharmaceuticals and personal care products. Concentration of these pollutants ranged from few ng L(-1) to higher values such as 30 μg L(-1) for industrial compounds in surface waters and up to 106 μg L(-1) for the pharmaceutical ibuprofen in wastewaters. Compounds already banned in Europe such as atrazine, alkylphenols and alkylphenol polyethoxylates are still found in surface waters, nevertheless their origin is still poorly understood. Beyond the contamination of the Portuguese aquatic environment by priority substances and emerging organic pollutants, this review also highlights the need of more research on other classes of pollutants and emphasizes the importance of extending this research to other locations in Portugal, which have not been investigated yet.

  16. Water management in cities of the future using emission control strategies for priority hazardous substances.

    PubMed

    Eriksson, E; Revitt, D M; Ledin, A; Lundy, L; Holten Lützhøft, H C; Wickman, T; Mikkelsen, P S

    2011-01-01

    Cities of the future face challenges with respect to the quantity and quality of water resources, and multiple managerial options need to be considered in order to safeguard urban surface water quality. In a recently completed project on 'Source control options for reducing emissions of Priority Pollutants' (ScorePP), seven emission control strategies (ECSs) were developed and tested within a semi-hypothetical case city (SHCC) to evaluate their potential to reduce the emission of selected European priority hazardous substances (PHSs) to surface waters. The ECSs included (1) business-as-usual, (2) full implementation of relevant European (EU) directives, (3) ECS2 in combination with voluntary options for household, municipalities and industry, (4) ECS2 combined with industrial treatment and best available technologies (BAT), (5) ECS2 in combination with stormwater and combined sewer overflow treatment, (6) ECS2 in combination with advanced wastewater treatment, and (7) combinations of ECS3-6. The SHCC approach was chosen to facilitate transparency, to allow compensating for data gaps and to decrease the level of uncertainty in the results. The selected PHSs: cadmium (Cd), hexachlorobenzene (HCB), nonylphenol (NP) and pentabromodiphenyl ether (PBDE) differ in their uses and environmental fate and therefore accumulate in surface waters to differing extents in response to the application of alternative ECS. To achieve the required reduction in PHS levels in urban waters the full implementation of existing EU regulation is prioritised and feasible combinations of managerial and technological options (source control and treatment) can be highly relevant for mitigating releases.

  17. Microbial processes and organic priority substances in marine coastal sediments (Adriatic Sea, Italy)

    NASA Astrophysics Data System (ADS)

    Zoppini, Annamaria; Ademollo, Nicoletta; Amalfitano, Stefano; Dellisanti, Walter; Lungarini, Silvia; Miserocchi, Stefano; Patrolecco, Luisa; Langone, Leonardo

    2015-04-01

    PERSEUS EU FP7 Project aims to identify the interacting patterns of natural and human-derived pressures to assess their impact on marine ecosystems and, using the objectives and principles of the Marine Strategy Framework Directive (MSFD) as a vehicle, to design an effective and innovative research governance framework based on sound scientific knowledge. In the frame of this Project (subtask 1.3.3 ADREX: Adriatic and Ionian Seas Experiment), monitoring surveys were conducted in the Adriatic Sea (Italy) in order to study the variation of structural and functional characteristics of native bacterial communities and the occurrence of selected classes of organic priority substances in sediments. The study area represents a good natural laboratory sensitive to climate variability and human pressure, owing to the semi-enclosed nature of the Adriatic Sea and to the increasing trend of human activities in the coastal regions. During the cruise ADRI-13 (November 2013) and ADRI-14 (October 2014) we sampled several coastal sites from the mouth of the Po River to the Otranto strait. Surface sediments were collected in all areas, while sediment cores were sampled in selected sites. Microbes associated with marine sediments play an important role in the C-flux being responsible for the transformation of organic detritus (autochthonous and allochthonous) into biomass. The sediment bacterial abundance was determined by epifluorescence microscopy and the rate of bacterial carbon production by measuring the 3H-leucine uptake rates. The community respiration rate was estimated by the measurement of the electron transport system (ETS) activity. The sediment contamination level was determined by measuring the concentration of contaminants included in the list of organic priority substances: PAHs, bisphenol A (BPA), alkylphenols (APs). The extraction/clean-up of PAHs, BPA and APs was performed by ultrasonic bath with the appropriate solvents, followed by analytical determination with

  18. 76 FR 81840 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). This direct final... Pollution Contingency Plan (NCP), which EPA promulgated pursuant to section 105 of the Comprehensive...

  19. 76 FR 76048 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Pollution Contingency Plan (NCP). This direct final deletion is being published by EPA with the concurrence... Part 300 which is the Oil and Hazardous Substances Pollution Contingency Plan (NCP), which EPA...

  20. 76 FR 32081 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-03

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Pollution Contingency Plan (NCP). This direct final deletion is being published by EPA with the concurrence... constitutes Appendix B of 40 CFR part 300, which is the National Oil and Hazardous Substances Pollution...

  1. Direct analysis of organic priority pollutants by IMS

    NASA Technical Reports Server (NTRS)

    Giam, C. S.; Reed, G. E.; Holliday, T. L.; Chang, L.; Rhodes, B. J.

    1995-01-01

    Many routine methods for monitoring of trace amounts of atmospheric organic pollutants consist of several steps. Typical steps are: (1) collection of the air sample; (2) trapping of organics from the sample; (3) extraction of the trapped organics; and (4) identification of the organics in the extract by GC (gas chromatography), HPLC (High Performance Liquid Chromatography), or MS (Mass Spectrometry). These methods are often cumbersome and time consuming. A simple and fast method for monitoring atmospheric organics using an IMS (Ion Mobility Spectrometer) is proposed. This method has a short sampling time and does not require extraction of the organics since the sample is placed directly in the IMS. The purpose of this study was to determine the responses in the IMS to organic 'priority pollutants'. Priority pollutants including representative polycyclic aromatic hydrocarbons (PAHs), phthalates, phenols, chlorinated pesticides, and polychlorinated biphenyls (PCB's) were analyzed in both the positive and negative detection mode at ambient atmospheric pressure. Detection mode and amount detected are presented.

  2. 76 FR 41719 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... Priorities List: Deletion of the Hipps Road Landfill Superfund Site AGENCY: Environmental Protection Agency... direct final Notice of Deletion of the Hipps Road Landfill Superfund Site (Site), located in Jacksonville... publishing this direct final Notice of Deletion of the Hipps Road Landfill (Site), from the...

  3. 76 FR 45432 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... direct final Notice of Deletion of the Palmer Barge Line (PBL) Superfund Site located in Port Arthur... Line (PBL) Superfund Site (Site), from the National Priorities List (NPL). The NPL constitutes Appendix... discusses the PBL Superfund Site and demonstrates how it meets the deletion criteria. Section V discusses...

  4. 76 FR 49324 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... Priorities List: Deletion of International Smelting and Refining Superfund Site AGENCY: Environmental... publishing a direct final Notice of Deletion of the International Smelting and Refining Superfund Site (Site... final Notice of Deletion of the International Smelting and Refining Superfund Site, (Site), from the...

  5. Directions in Substance Abuse Counseling, 2000.

    ERIC Educational Resources Information Center

    Cohen, Adam W., Ed.

    2000-01-01

    This volume of six lessons provides expert information on a variety of issues in substance abuse counseling. The lessons, which may be applied toward continuing education credits, are: (1) "Ethics in Substance Abuse Rehabilitation" (Robert L. Hewes); (2) "Addressing the Needs of Clients with Traumatic Injury and Alcoholism"…

  6. 77 FR 64748 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan; National... Pollution Contingency Plan (NCP). This direct final partial deletion is being published by EPA, with the... Michigan Smelter Tailings parcels of OU3 and the Mason Sands Tailings parcel of OU1. The following land...

  7. Emissions of organic pollutants from traffic and roads: Priority pollutants selection and substance flow analysis.

    PubMed

    Markiewicz, Anna; Björklund, Karin; Eriksson, Eva; Kalmykova, Yuliya; Strömvall, Ann-Margret; Siopi, Anna

    2017-02-15

    A large number of organic pollutants (OPs) emitted from vehicles and traffic-related activities exhibit environmental persistence and a tendency to bioaccumulate, and may have detrimental long-term effects on aquatic life. The aim of the study was to establish a list of significant sources of OPs occurring in road runoff, identify the OPs emitted from these sources, select a number of priority pollutants (PP), and estimate the quantity of PPs emitted in a road environment case study using substance flow analysis (SFA). The priority pollutants included in the SFA were selected from a list of approximately 1100 compounds found after comprehensive screening, including literature and database searches, expert judgments, the Ranking and Identification of Chemical Hazards method, and chemical analysis of sediments. The results showed the following priority order: polycyclic aromatic hydrocarbons (PAHs)>alkanes C20-C40>alkylphenols>phthalates>aldehydes>phenolic antioxidants>bisphenol A>oxygenated-PAHs>naphtha C5-C12>amides>amines. Among these, PAHs were chosen for a SFA, which was performed for a highway case study area in Gothenburg (Sweden). The SFA showed that the main sources of PAHs emitted in the area were vehicle exhaust gases, followed by tyre wear, motor lubricant oils, road surface wear, and brake linings. Only 2-6% of the total 5.8-29kg annually emitted PAHs/ha ended up in the stormwater sewer system. The measured PAH loads were found in much smaller amounts than the calculated loads and the outflow to stormwater contained much more of the hazardous PAHs than the total loads emitted in the catchment area.

  8. National superfund program priorities, fiscal year 1994. Directive

    SciTech Connect

    Not Available

    1994-01-31

    The memorandum provides the FY 1994 National Superfund Program Priorities for Regions and Headquarters. There are nine major Superfund priorities: Accelerated Cleanup and Emergency Response; Enforcement First; Enforcement Fairness; Military Base Closure; NPL Construction Completions; Contracts Management; Environmental Justice and Meaningful Community Involvement; Enhancement of State Role and Development of Deferral Options; and Innovative Technologies.

  9. Guidance on setting priorities for NPL candidate sites. Directive

    SciTech Connect

    Not Available

    1992-10-28

    The guidance document identifies factors that will help EPA regions decide the order in which they should consider sites with completed site inspections for inclusion on the NPL (National Priorities List).

  10. Enhancing biodegradability of priority substances (pesticides) by solar photo-Fenton.

    PubMed

    Lapertot, Milena; Pulgarín, César; Fernández-Ibáñez, Pilar; Maldonado, Manuel I; Pérez-Estrada, Leonidas; Oller, Isabel; Gernjak, Wolfgang; Malato, Sixto

    2006-03-01

    In this paper, we present the photo-Fenton treatment in a solar pilot-plant scale of several EU priority hazardous substances (Alachlor, Atrazine, Chlorfenvinphos, Diuron and Isoproturon) dissolved in water. The results have been evaluated not only from the point of view of contaminant disappearance and mineralisation, but also of toxicity reduction and enhancement of biodegradability. Degradation was monitored by total organic carbon, pesticide concentration by HPLC-UV, inorganics released by ion chromatography, and biodegradability by the Zahn-Wellens (Z-W) test. The total volume of the solar photoreactor, composed of compound parabolic collectors with a total area of 4.16m2, was between 70 and 82 L. The treatment was shown to be effective, mineralising all of the pesticides tested, both alone and in mixtures. In order to find out the conditions for biocompatibility using the photo-Fenton reaction as a pre-treatment step, wastewater inoculated with unacclimated municipal sludge containing pesticides after certain degradation time was evaluated by the Z-W test. Biodegradability was enhanced (70% considered biodegradable) by the photo-Fenton treatment after 12-25min. It may be concluded that the photo-Fenton treatment consistently enhances biodegradability of wastewater containing pesticides.

  11. Toxicity testing of NCSRP priority substances for the development of soil quality criteria

    SciTech Connect

    Cureton, P.M.; Balch, G.; Lintott, D.; Poirrier, K.; Goudey, S.

    1994-12-31

    The effects of 14 National Contaminated Sites Remediation Program (NCSRP) priority substances was measured on emergence and root elongation in lettuce (Lactuca saliva) and radish (Raphanus saliva) and on survival of the earthworm Eisenia foetida. The worm and seedling emergence tests were conducted in an artificial soil mixture composed of 10% peat moss, 20% kaolinite clay, and 70% silica sand (70 mesh) spiked with the contaminant. The root elongation tests were conducted on filter paper moistened with the contaminant solution. The following endpoints were derived on nominal and measured concentrations: NOEC, LOEC, the LC{sub 50} and LC{sub 25} for earthworm mortality and the EC{sub 50} and EC{sub 25} for emergence and root elongation. The contaminants tested included: arsenic, cadmium, chromium, copper, lead, mercury, zinc, vanadium, benzo(a)pyrene, cyanide, naphthalene, ethylene glycol, pentachlorophenol, and phenol. Each test was repeated three times using different batches of freshly prepared soil, seed lots and worm cultures. The authors will present the findings and discuss the application of toxicity test results in developing generic soil quality criteria.

  12. Implementation of E.U. Water Framework Directive: source assessment of metallic substances at catchment levels.

    PubMed

    Chon, Ho-Sik; Ohandja, Dieudonne-Guy; Voulvoulis, Nikolaos

    2010-01-01

    The E.U. Water Framework Directive (WFD) aims to prevent deterioration of water quality and to phase out or reduce the concentrations of priority substances at catchment levels. It requires changes in water management from a local scale to a river basin scale, and establishes Environmental Quality Standards (EQS) as a guideline for the chemical status of receiving waters. According to the Directive, the standard and the scope of the investigation for water management are more stringent and expanded than in the past, and this change also needs to be applied to restoring the level of metals in water bodies. The aim of this study was to identify anthropogenic emission sources of metallic substances at catchment levels. Potential sources providing substantial amounts of such substances in receiving waters included stormwater, industrial effluents, treated effluents, agricultural drainage, sediments, mining drainage and landfill leachates. Metallic substances have more emission sources than other dangerous substances at catchment levels. Therefore, source assessment for these substances is required to be considered more significantly to restore their chemical status in the context of the WFD. To improve source assessment quality, research on the role of societal and environmental parameters and contribution of each source to the chemical distribution in receiving waters need to be carried out.

  13. (Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.

    PubMed

    Van Bossuyt, Melissa; Van Hoeck, Els; Raitano, Giuseppa; Manganelli, Serena; Braeken, Els; Ates, Gamze; Vanhaecke, Tamara; Van Miert, Sabine; Benfenati, Emilio; Mertens, Birgit; Rogiers, Vera

    2017-04-01

    Over the last years, more stringent safety requirements for an increasing number of chemicals across many regulatory fields (e.g. industrial chemicals, pharmaceuticals, food, cosmetics, …) have triggered the need for an efficient screening strategy to prioritize the substances of highest concern. In this context, alternative methods such as in silico (i.e. computational) techniques gain more and more importance. In the current study, a new prioritization strategy for identifying potentially mutagenic substances was developed based on the combination of multiple (quantitative) structure-activity relationship ((Q)SAR) tools. Non-evaluated substances used in printed paper and board food contact materials (FCM) were selected for a case study. By applying our strategy, 106 out of the 1723 substances were assigned 'high priority' as they were predicted mutagenic by 4 different (Q)SAR models. Information provided within the models allowed to identify 53 substances for which Ames mutagenicity prediction already has in vitro Ames test results. For further prioritization, additional support could be obtained by applying local i.e. specific models, as demonstrated here for aromatic azo compounds, typically found in printed paper and board FCM. The strategy developed here can easily be applied to other groups of chemicals facing the same need for priority ranking.

  14. A review on the application of constructed wetlands for the removal of priority substances and contaminants of emerging concern listed in recently launched EU legislation.

    PubMed

    Gorito, Ana M; Ribeiro, Ana R; Almeida, C M R; Silva, Adrián M T

    2017-08-01

    The presence of organic pollutants in the aquatic environment, usually found at trace concentrations (i.e., between ng L(-1) and μg L(-1) or even lower, known as micropollutants), has been highlighted in recent decades as a worldwide environmental concern due to their difficult elimination by conventional water and wastewater treatment processes. The relevant information on constructed wetlands (CWs) and their application for the removal of a specific group of pollutants, 41 organic priority substances/classes of substances (PSs) and 8 certain other substances with environmental quality standards (EQS) listed in Directive 2013/39/EU as well as 17 contaminants of emerging concern (CECs) of the Watch List of Decision 2015/495/EU, is herein reviewed. Studies were found for 24 PSs and 2 other substances with EQS: octylphenol, nonylphenol, perfluorooctane sulfonic acid, di(2-ethylhexyl)phthalate, trichloromethane, dichloromethane, 1,2-dichloroethane, pentachlorobenzene, benzene, polychlorinated dibenzo-p-dioxins, naphthalene, fluoranthene, trifluralin, alachlor, isoproturon, diuron, tributyltin compounds, simazine, atrazine, chlorpyrifos (chlorpyrifos-ethyl), chlorfenvinphos, hexachlorobenzene, pentachlorophenol, endosulfan, dichlorodiphenyltrichloroethane (or DDT) and dieldrin. A few reports were also published for 8 CECs: imidacloprid, erythromycin, clarithromycin, azithromycin, diclofenac, estrone, 17-beta-estradiol and 17-alpha-ethinylestradiol. No references were found for the other 17 PSs, 6 certain other substances with EQS and 9 CECs listed in EU legislation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Occurrence of emerging contaminants, priority substances (2008/105/CE) and heavy metals in treated wastewater and groundwater at Depurbaix facility (Barcelona, Spain).

    PubMed

    Teijon, Gloria; Candela, Lucila; Tamoh, Karim; Molina-Díaz, Antonio; Fernández-Alba, A R

    2010-08-01

    The presence of 170 pharmaceuticals, personal care products, priority substances according to the 2008/105EU Directive and four metals (Cd, Ni, Hg, Pb) have been investigated at the Llobregat delta, south of Barcelona (Spain). In the area, reclaimed water is destined to satisfy environmental uses, irrigation and the construction of a hydraulic barrier against seawater intrusion in the deep aquifer of the delta. A monitoring survey was undertaken of water samples from a tertiary wastewater treatment plant (Depurbaix), treated waste water with an additional treatment of ultrafiltration, reverse osmosis, and UV disinfection (WWATP, for the hydraulic barrier injection). Groundwater samples from the aquifer receiving recharge were also investigated. The pharmaceutical group of substances was detected in sampled waters at concentrations rarely exceeding a few microg/L, among the compounds Caffeine, Nicotine and Galaxolide (musk fragrance) were found to be present in more than 60% of the samples. Diuron was the only priority substance detected. The four metals were always present in a variable concentration. After the WWATP treatment the majority of analytes are removed from tertiary treated wastewater or their concentration is reduced below 0.1 microg/L. Monitoring revealed a widespread occurrence of analysed compounds in groundwater. Among them Codeine (analgesic), Ibuprofen (anti-inflammatory), Iopamidol, Iopromide (contrast agent) and Paraxanthine (metabolite of caffeine) have only been detected in groundwater, and are not present in water currently being injected in the deep aquifer.

  16. 76 FR 57662 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... Environmental protection, Air pollution control, Chemicals, Hazardous waste, Hazardous substances, Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  17. 76 FR 57701 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... Environmental protection, Air pollution control, Chemicals, Hazardous waste, Hazardous substances, Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  18. 76 FR 57661 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... protection, Air pollution control, Chemicals, Hazardous waste, Hazardous substances, Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National...

  19. 78 FR 44512 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ... relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of California...

  20. 76 FR 57702 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... Environmental protection, Air pollution control, Chemicals, Hazardous waste, Hazardous substances, Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan National...

  1. 78 FR 66325 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ..., Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of South Carolina...

  2. 78 FR 45905 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ..., Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the Commonwealth of Pennsylvania, through the...

  3. 75 FR 27255 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ... relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of Louisiana, through the Louisiana...

  4. 77 FR 14717 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of South Dakota, through the Department of... Substances Pollution Contingency Plan (NCP), which EPA promulgated pursuant to section 105 of...

  5. 76 FR 70057 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan; National..., is an appendix to the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). This... constitutes Appendix B of 40 CFR part 300, which is the National Oil and Hazardous Substances Pollution...

  6. Construction of a chemical ranking system of soil pollution substances for screening of priority soil contaminants in Korea.

    PubMed

    Jeong, Seung-Woo; An, Youn-Joo

    2012-04-01

    The Korean government recently proposed expanding the number of soil-quality standards to 30 by 2015. The objectives of our study were to construct a reasonable protocol for screening priority soil contaminants for inclusion in the planned soil quality standard expansion. The chemical ranking system of soil pollution substances (CROSS) was first developed to serve as an analytical tool in chemical scoring and ranking of possible soil pollution substances. CROSS incorporates important parameters commonly used in several previous chemical ranking and scoring systems and the new soil pollution parameters. CROSS uses soil-related parameters in its algorithm, including information related to the soil environment, such as soil ecotoxicological data, the soil toxic release inventory (TRI), and soil partitioning coefficients. Soil TRI and monitoring data were incorporated as local specific parameters. In addition, CROSS scores the transportability of chemicals in soil because soil contamination may result in groundwater contamination. Dermal toxicity was used in CROSS only to consider contact with soil. CROSS uses a certainty score to incorporate data uncertainty. CROSS scores the importance of each candidate substance and assigns rankings on the basis of total scores. Cadmium was the most highly ranked. Generally, metals were ranked higher than other substances. Pentachlorophenol, phenol, dieldrin, and methyl tert-butyl ether were ranked the highest among chlorinated compounds, aromatic compounds, pesticides, and others, respectively. The priority substance list generated from CROSS will be used in selecting substances for possible inclusion in the Korean soil quality standard expansion; it will also provide important information for designing a soil-environment management scheme.

  7. Monitoring priority substances, other organic contaminants and heavy metals in a volcanic aquifer from different sources and hydrological processes.

    PubMed

    Estevez, Esmeralda; Cabrera, María del Carmen; Fernández-Vera, Juan Ramón; Molina-Díaz, Antonio; Robles-Molina, José; Palacios-Díaz, María del Pino

    2016-05-01

    Irrigation with reclaimed water (R) is necessary to guarantee the sustainability of semi-arid areas. Results obtained during a two years monitoring network (2009-2011) in Gran Canaria are presented, including the analysis of chemical parameters, N and S isotopes, priority substances (2008/105/EC, 2013/39/EU), other organic contaminants and heavy metals in groundwater and R used to irrigate a golf course. The aims of this work are to evaluate the contamination in a volcanic aquifer, relate the presence of organic contaminants and heavy metals with the hydrogeochemistry and identify pollution sources in the area. No priority substance exceeded the EU thresholds for surface water, although seventeen were detected in R. The most frequent compounds were hexachlorobenzene, chlorpyrifos ethyl, fluorene, phenanthrene and pyrene. These compounds were detected at low concentration, except chlorpyrifos. Chlorpyrifos ethyl, terbuthylazine, diuron, terbutryn, procymidone, atrazine and propazine exceeded the European threshold concentration for pesticides in groundwater (100ngL(-1)). Therefore, the priority substances chlorpyrifos ethyl and diuron must be included in monitoring studies. The priority pesticides chlorfenvinphos and diazinon were always detected in R but rarely in groundwater. Besides, the existence of contaminants not related to the current R irrigation has been identified. Absence of environmental problems related to heavy metals can be expected. The relationship among contaminant presence, hydrogeochemistry, including the stable isotopic prints of δ(18)O, δ(15)N and δ(34)S and preferential recharge paths has been described. The coastal well shows high values of EC, nitrate, a variable chemistry, and 50% of organic contaminants detected above 100ngL(-1). The well located in the recharge area presents a stable hydrochemistry, the lowest value of δ(15)N and the lowest contaminants occurrence. The area is an example of a complex volcanic media with several

  8. 78 FR 60809 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ...), located in Paris, New York, from the National Priorities List (NPL) and requests public comments on this.... to 5:00 p.m., and Town of Paris, Town Hall, 2580 Sulphur Springs Road, Sauquoit, NY 13456-0451, Phone...

  9. 78 FR 45167 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... Priorities List: Deletion of the Cannon Engineering Corp. (CEC), Superfund Site AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule; notice of intent. SUMMARY: The Environmental Protection... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION...

  10. Priority substances in sediments of the "Carska Bara" special nature reserve, a natural scientific research area on the UNESCO list.

    PubMed

    Grba, Nenad; Krčmar, Dejan; Isakovski, Marijana Kragulj; Jazić, Jelena Molnar; Maletić, Snežana; Pešić, Vesna; Dalmacija, Božo

    2016-11-01

    Surface sediments were subject to systematic long-term monitoring (2002-2014) in the Republic of Serbia (Province of Vojvodina). Eight heavy metals (Ni, Zn, Cd, Cr, Cu, Pb, As and Hg), mineral oils (total petroleum hydrocarbons), 16 EPA PAHs, selected pesticides and polychlorinated biphenyls (PCB) were monitored. As part of this research, this paper presents a sediment contamination spatial and temporal trend study of diverse pollution sources and the ecological risk status of the alluvial sediments of Carska Bara at three representative sampling sites (S1S3), in order to establish the status of contamination and recommend substances of interest for more widespread future monitoring. Multivariate statistical methods including factor analysis of principal component analysis (PCA/FA), Pearson correlation and several synthetic indicators were used to evaluate the extent and origin of contamination (anthropogenic or natural, geogenic sources) and potential ecological risks. Hg, Cd, As, mineral oils and PAHs (dominated by dibenzo(a,h)anthracene and benzo(a)pyrene, contributing 85.7% of the total) are derived from several anthropogenic sources, whereas Ni, Cu, Cr and Zn are convincingly of geogenic origin, and exhibit dual origins. Cd and Hg significantly raise the levels of potential ecological risk for all sampling locations, demonstrating the effect of long-term bioaccumulation and biomagnification. Pb is isolated from the other parameters, implying unique sources. This research suggests four heavy metals (Zn, Cr, Cu and As) and dibenzo(a,h)anthracene be added to the list of priority pollutants within the context of the application of the European Water Framework Directive (WFD), in accordance with significant national and similar environmental data from countries in the region.

  11. 78 FR 47267 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of Oklahoma, through the...

  12. 76 FR 76336 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of Texas, through the Texas Commission...

  13. 76 FR 45484 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of Texas, through the Texas Commission...

  14. 76 FR 49397 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of Utah, through the Utah Department...

  15. 76 FR 30081 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... (CERCLA) of 1980, as amended, is an appendix of the National Oil and Hazardous Substances Pollution... and Environment (CDPHE), have determined that all appropriate response actions at these...

  16. 78 FR 56611 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National..., is an appendix of the National Oil and ] Hazardous Substances Pollution Contingency Plan (NCP). The... risk to public health, welfare, or the environment. Deletion from the NPL does not preclude...

  17. 75 FR 55479 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... appendix of the National Oil and ] Hazardous Substances Pollution Contingency Plan (NCP). This partial... the State of Colorado, through the Colorado Department of Public Health and Environment (CDPHE),...

  18. 77 FR 31215 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National..., as amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan... EPA and the State of South Dakota, through the Department of Environment and Natural Resources,...

  19. 76 FR 11350 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... (CERCLA) of 1980, as amended, is an appendix of the National Oil and Hazardous Substances Pollution... EPA and the State of New Mexico, through the New Mexico Environment Department (NMED), have...

  20. 76 FR 71500 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan National... Superfund) of 1980, as amended, is an appendix of the National Oil and Hazardous Substances Pollution... Environment and Natural Resources (DENR), has determined that all appropriate response actions under...

  1. 75 FR 63140 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of Colorado, through the Colorado Department of Public Health and Environment (CDPHE), have determined that all appropriate response...

  2. 76 FR 58404 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). This partial deletion pertains to the remaining portions of OU9... Health and Environment, have determined that all appropriate response actions under CERCLA, other...

  3. 77 FR 2911 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-20

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of North Carolina, through the Department of Environment and Natural Resources...

  4. 77 FR 58321 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). EPA and the State of North Carolina, through the North Carolina Department of Environment and Natural Resources...

  5. 77 FR 43567 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of New Jersey, through the NJ Department...

  6. 76 FR 41751 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ..., Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... (CERCLA) of 1980, as amended, is an appendix of the National Oil and Hazardous Substances Pollution...

  7. 78 FR 69360 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the...

  8. 75 FR 48895 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List: Intent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan National... and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of Arkansas, through...

  9. 77 FR 67783 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ..., Reporting and recordkeeping requirements, Superfund, Water pollution control, and Water supply. Dated... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan National..., is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). EPA and...

  10. 76 FR 76118 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ..., Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of Texas, through the...

  11. 78 FR 48844 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-12

    ..., Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The...

  12. 78 FR 63099 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ..., Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Dated: September... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of New York, through...

  13. 75 FR 47521 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List: Intent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ..., Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan; National... 1980, as amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency...

  14. 76 FR 50441 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of New Jersey, through the New Jersey...

  15. 76 FR 32115 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-03

    ..., Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of Delaware...

  16. 75 FR 53268 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of Georgia, through the Georgia...

  17. 76 FR 51316 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the Commonwealth of Puerto Rico, through the Puerto...

  18. 77 FR 50070 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ..., Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of New York, through the Department of...

  19. 76 FR 45483 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of Texas, through the...

  20. 76 FR 50164 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan National... Substances Pollution Contingency Plan (NCP). EPA and the State of New York, through the Department of...

  1. 78 FR 65210 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ..., Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of California...

  2. 75 FR 26166 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ..., Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan National... 40 CFR part 300 which is the National Oil and Hazardous Substances Pollution Contingency Plan (NCP...

  3. 77 FR 64790 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ..., Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, and Water supply... AGENCY 40 CFR Part 300 ] National Oil and Hazardous Substances Pollution Contingency Plan; National... and Hazardous Substances Pollution Contingency Plan (NCP). EPA and the State of Michigan, through the...

  4. 76 FR 70105 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List: Partial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan National... amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). EPA...

  5. 76 FR 20605 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ..., Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan National... National Oil and Hazardous Substances Pollution Contingency Plan (NCP). EPA and the State of Michigan...

  6. 77 FR 50069 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ... relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... (CERCLA) of 1980, as amended, is an appendix of the National Oil and Hazardous Substances Pollution...

  7. 76 FR 81904 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the State of Florida, through the Florida Department...

  8. 75 FR 43115 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Substances Pollution Contingency Plan (NCP). The EPA and the Commonwealth of Pennsylvania, through the... partial deletion pertains to the soil and groundwater of parcels 24, 27, 28, 2-53, 2-53L, 2-54, 2-54L,...

  9. 76 FR 60777 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Hazardous Substances Pollution Contingency Plan (NCP). EPA, with the concurrence of the State of North... Pollution Contingency Plan (NCP), which EPA promulgated pursuant to Section 105 of the Comprehensive...

  10. 76 FR 77457 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... of Subjects in 40 CFR Part 300 Environmental protection, Air pollution control, Chemicals, Hazardous... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  11. 78 FR 73449 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ... Priorities List: Partial Deletion of the Omaha Lead Superfund Site AGENCY: Environmental Protection Agency... Partially Delete (NOIPD) of the Omaha Lead Superfund Site (Site) located in Omaha, Nebraska from the... residential parcels with soil lead levels at or above 400 parts per million (ppm) will remain on the NPL and...

  12. 78 FR 11620 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... Priorities List: Deletion of the Kerr-McGee (Sewage Treatment Plant) Superfund Site AGENCY: Environmental... Agency (EPA) Region 5 is issuing a Notice of Intent to Delete the Kerr-McGee Sewage Treatment Plant... Kerr-McGee (Sewage Treatment Plant) Superfund Site without prior Notice of Intent to Delete because...

  13. 77 FR 21919 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ...) located in Greenup, Illinois from the National Priorities List (NPL) and requests public comments on this proposed action. The NPL, promulgated pursuant to Section 105 of the Comprehensive Environmental Response... instructions for submitting comments. Email: Gladys Beard, NPL Deletion Process Manager, at...

  14. 75 FR 42361 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... Priorities List: Partial Deletion of the Rocky Mountain Arsenal Federal Facility AGENCY: Environmental... Protection Agency (EPA) Region 8 issued a Notice of Intent to Delete portions of the Rocky Mountain Arsenal... legal holidays; and the --Joint Administrative Records Document Facility, Rocky Mountain ] Arsenal, 5650...

  15. 75 FR 33747 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ..., Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... underlying ground water of the approximately 8-acre western portion of Operable Unit 1 of the...

  16. 78 FR 57799 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan National....dante@epa.gov . List of Subjects in 40 CFR Part 300 Environmental protection, Air pollution control...

  17. 76 FR 18136 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ..., Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... Pollution Contingency Plan (NCP). The EPA and the Commonwealth of Massachusetts, through the Massachusetts...

  18. 76 FR 56362 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... requirements, Superfund, Water pollution control, Water Supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan National... INFORMATION: List of Subjects in 40 CFR Part 300 Environmental protection, Air pollution control, Chemicals...

  19. 77 FR 59338 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-27

    ... recordkeeping requirements, Superfund, Water pollution control, Water Supply. Authority: 33 U.S.C. 1321(c)(2...-1983-0002; FRL-9735-3] National Oil and Hazardous Substances Pollution Contingency Plan; National... . SUPPLEMENTARY INFORMATION: List of Subjects in 40 CFR Part 300 Environmental protection, Air pollution control...

  20. 76 FR 56294 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ..., Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan National... in 40 CFR Part 300 Environmental protection, Air pollution control, Chemicals, Hazardous Waste...

  1. 76 FR 42055 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... recordkeeping requirements, Superfund, Water pollution control, Water Supply. Authority: 33 U.S.C. 1321(c)(2... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National... . SUPPLEMENTARY INFORMATION: List of Subjects in 40 CFR Part 300 Environmental protection, Air pollution control...

  2. High-Priority Directions of Modernization of University Education in Innovational Society

    ERIC Educational Resources Information Center

    Sergeev, Nikolai

    2017-01-01

    Purpose: The purpose of this paper is to verify the offered hypothesis and to determine high-priority directions of modernization of university education in an innovational society by the example of modern Russia. Design/methodology/approach: During the empirical study of connection between university education and innovational development of…

  3. High-Priority Directions of Modernization of University Education in Innovational Society

    ERIC Educational Resources Information Center

    Sergeev, Nikolai

    2017-01-01

    Purpose: The purpose of this paper is to verify the offered hypothesis and to determine high-priority directions of modernization of university education in an innovational society by the example of modern Russia. Design/methodology/approach: During the empirical study of connection between university education and innovational development of…

  4. Priority substances in a SW European coastal lagoon - Ria Formosa, Portugal. Twenty years of temporal evolution of metals and butyltins

    NASA Astrophysics Data System (ADS)

    Moreira da Silva, Manuela; Carvalho, Pedro; Paquete, Rita; Nuno Duarte, Duarte; Chícharo, Luís

    2013-04-01

    In the last years the European Union has decided to specifically include nickel, cadmium, plumb and TBT in its list of priority substances in water. Trace metals pose a significant threat to organisms because above threshold availability, act as enzyme inhibitors resulting in adverse ecological effects to sediment-associated biota (e.g. macrophytes, benthos, demersal fish) and to higher-biota (e.g. pelagic fish and aquatic birds). Since 2003 International Maritime Organization called for a ban of the application of tributyltin-based paints. Wide distribution, high hydrophobicity, and persistence of organotin compounds have raised concern about their bioaccumulation, their potential biomagnification in the food webs, and their adverse effects to human health and environment, particularly most recent reviews focuses on possible endocrine disrupting effects of OT's (Galloway, 2006; Nakanishi, 2007; Takahashi et al., 1999; Veltman et al., 2006). Saltmarshes are highly heterogeneous environments that have been suffered pressures by the increasing urbanization and industrialization in the adjacent areas. Saltmarsh sediments integrate inputs of contaminants, like metals and organotin compounds and may act as long-term sources of contaminants. At the Ria Formosa saltmarsh several activities were responsible for long-term contaminants, some of them considered priority substances. This work aims to provide information about the present levels and temporal evolution in the last decades of metals (Mn, Zn, Cu, Cr, Ni, Pb, Mo, Cd and Ag, in addition to Fe and Al) and butyltins (TBT, DBT and MBT) in saltmarsh sediments at south of Portugal. Metals were analysed by atomic absorption spectrometry-AAS. Butyltins were determined, after derivatization, by solid phase micro extraction combined with gas chromatography with mass spectrometry (MS/MS). Results showed that legislation was an effective instrument for the decreasing of contamination levels, to sustainable values to ecosystem

  5. Vital Directions for Health and Health Care: Priorities From a National Academy of Medicine Initiative.

    PubMed

    Dzau, Victor J; McClellan, Mark B; McGinnis, J Michael; Burke, Sheila P; Coye, Molly J; Diaz, Angela; Daschle, Thomas A; Frist, William H; Gaines, Martha; Hamburg, Margaret A; Henney, Jane E; Kumanyika, Shiriki; Leavitt, Michael O; Parker, Ruth M; Sandy, Lewis G; Schaeffer, Leonard D; Steele, Glenn D; Thompson, Pamela; Zerhouni, Elias

    2017-04-11

    Recent discussion has focused on questions related to the repeal and replacement of portions of the Affordable Care Act (ACA). However, issues central to the future of health and health care in the United States transcend the ACA provisions receiving the greatest attention. Initiatives directed to certain strategic and infrastructure priorities are vital to achieve better health at lower cost. To review the most salient health challenges and opportunities facing the United States, to identify practical and achievable priorities essential to health progress, and to present policy initiatives critical to the nation's health and fiscal integrity. Qualitative synthesis of 19 National Academy of Medicine-commissioned white papers, with supplemental review and analysis of publicly available data and published research findings. The US health system faces major challenges. Health care costs remain high at $3.2 trillion spent annually, of which an estimated 30% is related to waste, inefficiencies, and excessive prices; health disparities are persistent and worsening; and the health and financial burdens of chronic illness and disability are straining families and communities. Concurrently, promising opportunities and knowledge to achieve change exist. Across the 19 discussion papers examined, 8 crosscutting policy directions were identified as vital to the nation's health and fiscal future, including 4 action priorities and 4 essential infrastructure needs. The action priorities-pay for value, empower people, activate communities, and connect care-recurred across the articles as direct and strategic opportunities to advance a more efficient, equitable, and patient- and community-focused health system. The essential infrastructure needs-measure what matters most, modernize skills, accelerate real-world evidence, and advance science-were the most commonly cited foundational elements to ensure progress. The action priorities and essential infrastructure needs represent major

  6. Organic priority substances and microbial processes in river sediments subject to contrasting hydrological conditions.

    PubMed

    Zoppini, Annamaria; Ademollo, Nicoletta; Amalfitano, Stefano; Casella, Patrizia; Patrolecco, Luisa; Polesello, Stefano

    2014-06-15

    Flood and drought events of higher intensity and frequency are expected to increase in arid and semi-arid regions, in which temporary rivers represent both a water resource and an aquatic ecosystem to be preserved. In this study, we explored the variation of two classes of hazardous substances (Polycyclic Aromatic Hydrocarbons and Nonylphenols) and the functioning of the microbial community in river sediments subject to hydrological fluctuations (Candelaro river basin, Italy). Overall, the concentration of pollutants (∑PAHs range 8-275ngg(-1); ∑NPs range 299-4858ngg(-1)) suggests a moderate degree of contamination. The conditions in which the sediments were tested, flow (high/low) and no flow (wet/dry/arid), were associated to significant differences in the chemical and microbial properties. The total organic carbon contribution decreased together with the stream flow reduction, while the contribution of C-PAHs and C-NPs tended to increase. NPs were relatively more concentrated in sediments under high flow, while the more hydrophobic PAHs accumulated under low and no flow conditions. Passing from high to no flow conditions, a gradual reduction of microbial processes was observed, to reach the lowest specific bacterial carbon production rates (0.06fmolCh(-1)cell(-1)), extracellular enzyme activities, and the highest doubling time (40h) in arid sediments. In conclusion, different scenarios for the mobilization of pollutants and microbial processes can be identified under contrasting hydrological conditions: (i) the mobilization of pollutants under high flow and a relatively higher probability for biodegradation; (ii) the accumulation of pollutants during low flow and lower probability for biodegradation; (iii) the drastic reduction of pollutant concentrations under dry and arid conditions, probably independently from the microbial activity (abiotic processes). Our findings let us infer that a multiple approach has to be considered for an appropriate water

  7. 76 FR 76314 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ...). Benzo(a)pyrene--2.3 mg/kg. Benzo(a)anthracene--23.0 mg/kg. Dieldrin--1.2 mg/kg. Heptachlor Epoxide--2.1.... ACTION: Direct final rule. SUMMARY: The Environmental Protection Agency (EPA) Region 6 is publishing a... January 6, 2012. If adverse comments are received, EPA will publish a timely withdrawal of the...

  8. 78 FR 11589 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... deletion does not preclude future actions under Superfund. DATES: This direct final deletion is effective... future conditions warrant such actions. Because EPA considers this action to be noncontroversial and... for future response actions, should future conditions warrant such actions. IV. Basis for...

  9. 78 FR 66283 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... ground water above drinking water standards; and potential direct contact exposure to environmental... for contaminants in the ground water based on drinking water standards. The selected remedy eliminated... contaminants to the ground water and by remediating ground water to drinking water standards. The 1987 ROD...

  10. Patient Priority-Directed Decision Making and Care for Older Adults with Multiple Chronic Conditions.

    PubMed

    Tinetti, Mary E; Esterson, Jessica; Ferris, Rosie; Posner, Philip; Blaum, Caroline S

    2016-05-01

    Older adults with multiple conditions receive care that is often fragmented, burdensome, and of unclear benefit. An advisory group of patients, caregivers, clinicians, health system engineers, health care system leaders, payers, and others identified three modifiable contributors to this fragmented, burdensome care: decision making and care focused on diseases, not patients; inadequate delineation of roles and responsibilities and accountability among clinicians; and lack of attention to what matters to patients and caregivers (ie, their health outcome goals and care preferences). The advisory group identified patient priority-directed care as a feasible, sustainable approach to addressing these modifiable factors. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Using early life stages of marine animals to screen the toxicity of priority hazardous and noxious substances.

    PubMed

    Cunha, Isabel; Torres, Tiago; Oliveira, Helena; Martins, Rosário; McGowan, Thomas; Sheahan, David; Santos, Miguel Machado

    2017-04-01

    This study provides toxicity values for early life stages (ELS) of two phylogenetically distinct marine animal taxa, the sea urchin (Paracentrotus lividus), a deuterostome invertebrate, and the turbot (Scophthalmus maximus), a vertebrate (teleost), when challenged by six hazardous and noxious substances (HNS): aniline, butyl acrylate, m-cresol, cyclohexylbenzene, hexane and trichloroethylene. The aim of the study was to provide preliminary information on toxic effects of representative and relevant priority HNS to assess the risk posed by spills to marine habitats and therefore improve preparedness and the response at the operational level. Selection criteria to include each compound in the study were (1) inclusion in the HASREP (2005) list; (2) presence on the priority list established by Neuparth et al. (2011); (3) paucity of toxicological data (TOXnet and ECOTOX) for marine organisms; (4) behaviour in the water according to the categories defined by the European Behaviour classification system (GESAMP 2002), by selecting compounds with different behaviours in water; and (5) physicochemical and toxicological properties, where available, in order to anticipate the most toxic compounds. Aniline and m-cresol were the most toxic compounds with no observed apical effect concentration (NOAEC) values for sea urchin ranging between 0.01 and 0.1 mg/L, followed by butyl acrylate and cyclohexylbenzene with NOAECs ranging between 0.1 and 1.0 mg/L and trichloroethylene with NOAEC values that were in the range between 1 and 10 mg/L, reflecting their behaviour in water, mostly vapour pressure, but also solubility and log Kow. Hexane was toxic only for turbot embryos, due to its neurotoxic effects, and not for sea urchin larvae, at concentrations in the range between 1 and 10 mg/L. The concentrations tested were of the same order of magnitude for both species, and it was observed that sea urchin embryos (length of the longest arm) are more sensitive than turbot eggs larvae

  12. Testing decisions of the TSCA Interagency Testing Committee for chemicals on the Canadian Environmental Protection Act Domestic Substances List and Priority Substances List: Di-tert-butylphenol, ethyl benzene, brominated flame retardants, phthalate esters, chloroparaffins, chlorinated benzenes, and anilines

    SciTech Connect

    Walker, J.D.

    1996-12-31

    In 1976, under section 4(e) of the Toxic Substances Control Act (TSCA), the US Congress created the TSCA Interagency Testing Committee (ITC) to decide which chemicals should be recommended to the Administrator of the US Environmental Protection Agency for testing. In 1988, under the Canadian Environmental Protection Act (CEPA), the Government of Canada created the Domestic Substances List and Priority Substances List. This paper briefly describes the ITC, the different ITC testing decisions and a few of the ITC`s 11,150 testing decisions for the 21,413 chemicals on the CEPA Domestic Substances List and some of the 24 testing decisions for the 44 chemicals and chemical groups on the CEPA.

  13. Points mean prizes: priority points, preferential status and directed organ donation in Israel

    PubMed Central

    2014-01-01

    The introduction of Israel’s new Organ Transplantation Act in 2010 has enabled the development of a unique priority point system aimed at motivating individual’s to donate their organ. The priority point system rewards those who are willing to donate an organ with preferential status and an increased chance of receiving a donor organ, should they come to be in need of one. Preliminary evidence suggests it has considerable public support among Israelis, who appear willing to redress the challenge posed by those who are willing to accept an organ but not willing to donate. Since the Act’s introduction Israel has witnessed record numbers signing donor cards and there has been a significant increase in the actual numbers of transplants. One aspect of the new Israeli system that has hitherto not much been considered is its tendency towards a communitarian model of organ donation and the implications this change in emphasis may have for the existing ‘opt-in’ model based upon autonomy and consent. Gil Siegel draws our attention to this aspect when he sets out his defence of a proposal he refers to as ‘directed organ donation to other registered donors’, which encourages community responsibility without affecting the established commitment to consent and individual freedom. This commentary provides a brief overview of the new Act and its priority point system. It also examines Siegel’s proposal and considers the implications it may have for equity and justice, personal choice and dispositional authority. It is argued that although the proposal brings with it several inevitable hurdles for policy makers these are not insurmountable. Rather, its extraordinary potential to save life and avoid suffering should prompt urgent action at policy level. If such a scheme was successfully implemented in Israel it would represent a landmark change in organ donation and allocation policy, and set an example from which we all could learn. PMID:24565060

  14. Points mean prizes: priority points, preferential status and directed organ donation in Israel.

    PubMed

    Cronin, Antonia J

    2014-02-24

    The introduction of Israel's new Organ Transplantation Act in 2010 has enabled the development of a unique priority point system aimed at motivating individual's to donate their organ. The priority point system rewards those who are willing to donate an organ with preferential status and an increased chance of receiving a donor organ, should they come to be in need of one. Preliminary evidence suggests it has considerable public support among Israelis, who appear willing to redress the challenge posed by those who are willing to accept an organ but not willing to donate. Since the Act's introduction Israel has witnessed record numbers signing donor cards and there has been a significant increase in the actual numbers of transplants.One aspect of the new Israeli system that has hitherto not much been considered is its tendency towards a communitarian model of organ donation and the implications this change in emphasis may have for the existing 'opt-in' model based upon autonomy and consent. Gil Siegel draws our attention to this aspect when he sets out his defence of a proposal he refers to as 'directed organ donation to other registered donors', which encourages community responsibility without affecting the established commitment to consent and individual freedom.This commentary provides a brief overview of the new Act and its priority point system. It also examines Siegel's proposal and considers the implications it may have for equity and justice, personal choice and dispositional authority. It is argued that although the proposal brings with it several inevitable hurdles for policy makers these are not insurmountable. Rather, its extraordinary potential to save life and avoid suffering should prompt urgent action at policy level. If such a scheme was successfully implemented in Israel it would represent a landmark change in organ donation and allocation policy, and set an example from which we all could learn.

  15. Military Combat Deployments and Substance Use: Review and Future Directions

    PubMed Central

    LARSON, MARY JO; WOOTEN, NIKKI R.; ADAMS, RACHEL SAYKO; MERRICK, ELIZABETH L.

    2012-01-01

    Iraq and Afghanistan veterans experience extreme stressors and injuries during deployments, witnessing and participating in traumatic events. The military has organized prevention and treatment programs as a result of increasing suicides and posttraumatic stress disorder among troops; however, there is limited research on how to intervene with alcohol misuse and drug use that accompany these problems. This review presents statistics about post-deployment substance use problems and comorbidities, and discusses the military’s dual role in 1) enforcing troop readiness with its alcohol and drug policies and resiliency-building programs, and 2) seeking to provide treatment to troops with combat-acquired problems including substance abuse. PMID:22496626

  16. Organic and inorganic priority substances in sediments of Ludaš Lake, a cross-border natural resource on the Ramsar list.

    PubMed

    Grba, Nenad; Krčmar, Dejan; Maletić, Snežana; Bečelić-Tomin, Milena; Grgić, Marko; Pucar, Gordana; Dalmacija, Božo

    2017-01-01

    For the first time, long-term monitoring (from 2002 to 2014) was carried out of surface sediments in Ludaš Lake, a Ramsar site in northern Serbia. Organic (16 EPA PAHs, mineral oils, selected pesticides and polychlorinated biphenyls (PCBs)) and inorganic substances (eight heavy metals: Ni, Zn, Cd, Cr, Cu, Pb, As and Hg) were continually investigated. Dibenzo[a,h]anthracene (DahA) and fluorene (Flo) were found at levels indicative of causing adverse effects to biota. Diagnostic ratios of specific PAHs were dominated by high molecular weight components, particularly DahA, which contributed 81.78 % of the total high carcinogens, benzo[b]fluoranthene (BbF) and Flo. Potential ecological risk factors (ERi) and the high relative standard deviations (RSD) obtained (up to 245 %) for the parameters monitored confirm the high periodical anthropogenic impact from industry, municipal wastewater and agriculture. The highest concentration of inorganic pollution found was for Cd (440-831 mg/kg) at all sites, Cu (439 mg/kg) in the eastern part of the lake and Cu (388 mg/kg) and Hg (771 mg/kg) in the northern part of the lake. Based on factor analysis of principal component analysis (PCA/FA), As and phenanthrene (Phe) had significant loadings (0.808 and 0.907, respectively). This association of As with organic anthropogenic sources was also confirmed with the sum of PAHs, pyrene (Pyr) and mineral oil by 3D factor plot, corroborating the theory of As mobilization from metal-reducing microbes as organic (methylated) forms, accelerated by phenanthrene. According to EU national and regional data results, this research suggests that Cu, As, dibenzo[a,h]anthracene and Flo should be added to the list of priority pollutants within the context of applying the European Water Framework Directive (WFD).

  17. Substance use in women: Current status and future directions

    PubMed Central

    Lal, Rakesh; Deb, Koushik Sinha; Kedia, Swati

    2015-01-01

    Alcohol and substance use, until recently, were believed to be a predominantly male phenomenon. Only in the last few decades, attention has shifted to female drug use and its repercussions in women. As the numbers of female drug users continue to rise, studies attempt to understand gender-specific etiological factors, phenomenology, course and outcome, and issues related to treatment with the aim to develop more effective treatment programs. Research has primarily focused on alcohol and tobacco in women, and most of the literature is from the Western countries with data from developing countries like India being sparse. This review highlights the issues pertinent to alcohol and substance use in women with a special focus to the situation in India. PMID:26330645

  18. Longitudinal Bi-Directional Relationships between Sleep and Youth Substance Use

    ERIC Educational Resources Information Center

    Pasch, Keryn E.; Latimer, Lara A.; Cance, Jessica Duncan; Moe, Stacey G.; Lytle, Leslie A.

    2012-01-01

    Despite the known deficits in sleep that occur during adolescence and the high prevalence of substance use behaviors among this group, relatively little research has explored how sleep and substance use may be causally related. The purpose of this study was to explore the longitudinal bi-directional relationships between sleep duration, sleep…

  19. Longitudinal Bi-Directional Relationships between Sleep and Youth Substance Use

    ERIC Educational Resources Information Center

    Pasch, Keryn E.; Latimer, Lara A.; Cance, Jessica Duncan; Moe, Stacey G.; Lytle, Leslie A.

    2012-01-01

    Despite the known deficits in sleep that occur during adolescence and the high prevalence of substance use behaviors among this group, relatively little research has explored how sleep and substance use may be causally related. The purpose of this study was to explore the longitudinal bi-directional relationships between sleep duration, sleep…

  20. Research Priorities for Economic Analyses of Prevention: Current Issues & Future Directions

    PubMed Central

    Crowley, D. Max; Hill, Laura Griner; Kuklinski, Margaret R.; Jones, Damon E.

    2013-01-01

    In response to growing interest in economic analyses of prevention efforts, a diverse group of prevention researchers, economists, and policy analysts convened a scientific panel, on “Research Priorities in Economic Analysis of Prevention” at the 19th annual conference of the Society for Prevention Research. The panel articulated four priorities that, if followed in future research, would make economic analyses of prevention efforts easier to compare and more relevant to policymakers, and community stakeholders. These priorities are: (1) increased standardization of evaluation methods, (2) improved economic valuation of common prevention outcomes, (3) expanded efforts to maximize evaluation generalizability and impact, as well as (4) enhanced transparency and communicability of economic evaluations. In this paper we define three types of economic analyses in prevention, provide context and rationale for these four priorities as well as related sub-priorities, and discuss the challenges inherent in meeting them. PMID:23963624

  1. Use of Ozone-Depleting Substances. Direct final rule.

    PubMed

    2016-10-26

    The Food and Drug Administration (FDA, the Agency, or we) is amending its regulation on uses of ozone-depleting substances (ODSs), including chlorofluorocarbons (CFCs), to remove the designation for certain products as "essential uses" under the Clean Air Act. Essential-use products are exempt from the ban by FDA on the use of CFCs and other ODS propellants in FDA-regulated products and from the ban by the Environmental Protection Agency (EPA) on the use of ODSs in pressurized dispensers. The products that will no longer constitute an essential use are: Sterile aerosol talc administered intrapleurally by thoracoscopy for human use and metered-dose atropine sulfate aerosol human drugs administered by oral inhalation. FDA is taking this action because alternative products that do not use ODSs are now available and because these products are no longer being marketed in versions that contain ODSs.

  2. 76 FR 68193 - Notice of the Revised Priority List of Hazardous Substances That Will Be the Subject of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... a Completed Exposure Pathway Site Count Report. This report lists the number of sites or events at which ATSDR is involved and wherein a substance has been found in a completed exposure pathway (CEP... frequency-of-occurrence data, additional concentration data, and more information on exposure to...

  3. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4... Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological...

  4. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4... Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological...

  5. Identifying Research Priorities: Themes and Directions for the TESOL International Research Foundation.

    ERIC Educational Resources Information Center

    Tucker, G. Richard; Lightbown, Patsy M.; Snow, Catherine; Christian, Donna; de Bot, Kees; Lynch, Brian K.; Nunan, David; Duff, Patricia A.; Freeman, Donald; Bailey, Kathleen M.

    2001-01-01

    Highlights research priorities for the Teaching English to Speakers of Other Languages (TESOL) field, including the following: age of beginning instruction, learning to read in a second language, dual-language education for English language learners, language assessment and program evaluation, English as a global language, learning English for…

  6. Screening of emerging contaminants and priority substances (2008/105/EC) in reclaimed water for irrigation and groundwater in a volcanic aquifer (Gran Canaria, Canary Islands, Spain).

    PubMed

    Estévez, Esmeralda; Cabrera, María del Carmen; Molina-Díaz, Antonio; Robles-Molina, José; Palacios-Díaz, María del Pino

    2012-09-01

    In semiarid regions, reclaimed water can be an important source of emerging pollutants in groundwater. In Gran Canaria Island, reclaimed water irrigation has been practiced for over thirty years and currently represents 8% of water resources. The aim of this study was to monitor contaminants of emerging concern and priority substances (2008/105/EC) in a volcanic aquifer in the NE of Gran Canaria where the Bandama Golf Course has been sprinkled with reclaimed water since 1976. Reclaimed water and groundwater were monitoring quarterly from July 2009 to May 2010. Only 43% of the 183 pollutants analysed were detected: 42 pharmaceuticals, 20 pesticides, 12 polyaromatic hydrocarbons, 2 volatile organic compounds and 2 flame retardants. The most frequent compounds were caffeine, nicotine, chlorpyrifos ethyl, fluorene, phenanthrene and pyrene. Concentrations were always below 50 ng L(-1), although some pharmaceuticals and one pesticide, cholrpyrifos ethyl, were occasionally detected at higher concentrations. This priority substance for surface water exceeded the maximum threshold (0.1 μg L(-1)) for pesticide concentration in groundwater (2006/118/EC). Sorption and degradation processes in soil account for more compounds being detected in reclaimed water than in groundwater, and that some contaminants were always detected in reclaimed water, but never in groundwater (flufenamic acid, propyphenazone, terbutryn and diazinon). Furthermore, erythromycin was always detected in reclaimed water (exceeding occasionally 0.1 μg L(-1)), and was detected only once in groundwater. In contrast, some compounds (phenylephrine, nifuroxazide and miconazole) never detected in reclaimed water, were always detected in groundwater. This fact and the same concentration range detected for the groups, regardless of the water origin, indicated alternative contaminant sources (septic tanks, agricultural practices and sewerage breaks). The widespread detection of high adsorption potential compounds

  7. Longitudinal Bi-directional Relationships Between Sleep and Youth Substance Use

    PubMed Central

    Latimer, Lara A.; Cance, Jessica Duncan; Moe, Stacey G.; Lytle, Leslie A.

    2012-01-01

    Despite the known deficits in sleep that occur during adolescence and the high prevalence of substance use behaviors among this group, relatively little research has explored how sleep and substance use may be causally related. The purpose of this study was to explore the longitudinal bi-directional relationships between sleep duration, sleep patterns and youth substance use behaviors. Participants included 704 mostly white (86.4 %) youth, 51 % female, with a baseline mean age of 14.7 years. Self-reported substance use behaviors included past month alcohol, cigarette, and marijuana use. Sleep measures included sleep duration on weekends and weekdays, total sleep, weekend oversleep, and weekend sleep delay. Cross-lagged structural equation models, accounting for clustering at the school level, were run to determine the longitudinal association between sleep and substance use adjusting for socio-demographic characteristics, pubertal status, body mass index z-score, and depressive symptoms. Cigarette use and weekend sleep were bi-directionally related as were marijuana use and total sleep. No other bidirectional associations were identified. However, alcohol use predicted shorter weekend oversleep and marijuana use predicted increased weekend sleep and weekend oversleep. Sleep patterns and duration also predicted adolescents’ cigarette, alcohol, and marijuana use. Sleep, both patterns and duration, and substance use among youth are intertwined. Future research is needed to explore these bidirectional relationships, as well as other important contextual factors that may moderate these associations. PMID:22752878

  8. Rectal cancer: future directions and priorities for treatment, research and policy in New Zealand.

    PubMed

    Jackson, Christopher; Ehrenberg, Nieves; Frizelle, Frank; Sarfati, Diana; Balasingam, Adrian; Pearse, Maria; Parry, Susan; Print, Cristin; Findlay, Michael; Bissett, Ian

    2014-06-06

    New Zealand has one of the highest incidences of rectal cancer in the world, and its optimal management requires a multidisciplinary approach. A National Rectal Cancer Summit was convened in August 2013 to discuss management of rectal cancer in the New Zealand context, to highlight controversies and discuss domestic priorities for the future. This paper summarises the priorities for treatment, research and policy for rectal cancer services in New Zealand identified as part of the Summit in August. The following priorities were identified: - Access to high-quality information for service planning, review of outcomes, identification of inequities and gaps in provision, and quality improvement; - Engagement with the entire sector, including private providers; - Focus on equity; - Emerging technologies; - Harmonisation of best practice; - Importance of multidisciplinary team meetings. In conclusion, improvements in outcomes for patients with rectal cancer in New Zealand will require significant engagement between policy makers, providers, researchers, and patients in order to ensure equitable access to high quality treatment, and strategic incorporation of emerging technologies into clinical practice. A robust clinical information framework is required in order to facilitate monitoring of quality improvements and to ensure that equitable care is delivered.

  9. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Substances added directly to human food affirmed... FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE General Provisions § 184.1 Substances added... and handled as a food ingredient; and that the quantity of the ingredient added to food does...

  10. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Substances added directly to human food affirmed... FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE General Provisions § 184.1 Substances added... and handled as a food ingredient; and that the quantity of the ingredient added to food does...

  11. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Substances added directly to human food affirmed... FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE General Provisions § 184.1 Substances added... and handled as a food ingredient; and that the quantity of the ingredient added to food does...

  12. Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition.

    PubMed

    Patel, Vikram; Chisholm, Dan; Parikh, Rachana; Charlson, Fiona J; Degenhardt, Louisa; Dua, Tarun; Ferrari, Alize J; Hyman, Steve; Laxminarayan, Ramanan; Levin, Carol; Lund, Crick; Medina Mora, María Elena; Petersen, Inge; Scott, James; Shidhaye, Rahul; Vijayakumar, Lakshmi; Thornicroft, Graham; Whiteford, Harvey

    2016-04-16

    The burden of mental, neurological, and substance use (MNS) disorders increased by 41% between 1990 and 2010 and now accounts for one in every 10 lost years of health globally. This sobering statistic does not take into account the substantial excess mortality associated with these disorders or the social and economic consequences of MNS disorders on affected persons, their caregivers, and society. A wide variety of effective interventions, including drugs, psychological treatments, and social interventions, can prevent and treat MNS disorders. At the population-level platform of service delivery, best practices include legislative measures to restrict access to means of self-harm or suicide and to reduce the availability of and demand for alcohol. At the community-level platform, best practices include life-skills training in schools to build social and emotional competencies. At the health-care-level platform, we identify three delivery channels. Two of these delivery channels are especially relevant from a public health perspective: self-management (eg, web-based psychological therapy for depression and anxiety disorders) and primary care and community outreach (eg, non-specialist health worker delivering psychological and pharmacological management of selected disorders). The third delivery channel, hospital care, which includes specialist services for MNS disorders and first-level hospitals providing other types of services (such as general medicine, HIV, or paediatric care), play an important part for a smaller proportion of cases with severe, refractory, or emergency presentations and for the integration of mental health care in other health-care channels, respectively. The costs of providing a significantly scaled up package of specified cost-effective interventions for prioritised MNS disorders in low-income and lower-middle-income countries is estimated at US$3-4 per head of population per year. Since a substantial proportion of MNS disorders run a

  13. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Substances added directly to human food affirmed... RECOGNIZED AS SAFE General Provisions § 184.1 Substances added directly to human food affirmed as generally... ingredient added to food does not exceed the amount reasonably required to accomplish the intended...

  14. Characterization of the column-based priority logic readout of Topmetal-II‑ CMOS pixel direct charge sensor

    NASA Astrophysics Data System (ADS)

    An, M.; Zhang, W.; Xiao, L.; Gao, C.; Chen, C.; Han, M.; Huang, G.; Ji, R.; Li, X.; Liu, J.; Mei, Y.; Pei, H.; Sun, Q.; Sun, X.; Wang, K.; Yang, P.; Zhou, W.

    2017-03-01

    We present the detailed study of the digital readout of Topmetal-II- CMOS pixel direct charge sensor. Topmetal-II- is an integrated sensor with an array of 72×72 pixels each capable of directly collecting external charge through exposed metal electrodes in the topmost metal layer. In addition to the time-shared multiplexing readout of the analog output from Charge Sensitive Amplifiers in each pixel, hits are also generated through comparators in each pixel with individually adjustable thresholds. The hits are read out via a column-based priority logic structure, retaining both hit location and time information. The in-array column-based priority logic features with a full clock-less circuitry hence there is no continuously running clock distributed in the pixel and matrix logic. These characteristics enable its use as the charge readout device in future Time Projection Chambers without gaseous gain mechanism, which has unique advantages in low background and low rate-density experiments. We studied the detailed working behavior and performance of this readout, and demonstrated its functional validity and potential in imaging applications.

  15. Thermoelectric Devices, Being Blown Through with a Substance in the Direction of Heat Flow

    DTIC Science & Technology

    1974-04-06

    thermoelectric devices being blown through with a substance in the direction of heat flow are described. A battery of this kind of thermoelements can be use in...capillaries. A battery of these thermoelements can serve for utilizing the heat of combustion products produced in some heat-using facility. Tne...consumption of the heat carrier and its temperature ahead of the battery will be specified. If we know the geometrical characteristics of thermoelements

  16. African Language Instruction in the United States: Directions and Priorities for the 1980s.

    ERIC Educational Resources Information Center

    Wiley, David, Comp.; Dwyer, David, Comp.

    A conference of African scholars was held in the United States in 1979 to develop a consensus and a statement about the direction that African language teaching and learning should take in this decade. African languages are among the so-called "less-commonly taught languages," and funding for their teaching and study has come from…

  17. Multilevel Modeling of Direct Effects and Interactions of Peers, Parents, School, and Community Influences on Adolescent Substance Use

    ERIC Educational Resources Information Center

    Mayberry, Megan L.; Espelage, Dorothy L.; Koenig, Brian

    2009-01-01

    This study tested a social-ecological model of adolescent substance use. Multilevel modeling was used to investigate how systems, such as parents, peers, schools, and communities, directly influence and interact together to influence adolescent substance use. Participants included 14,548 (50.3% female) middle school students who were 78.6% White,…

  18. Multilevel Modeling of Direct Effects and Interactions of Peers, Parents, School, and Community Influences on Adolescent Substance Use

    ERIC Educational Resources Information Center

    Mayberry, Megan L.; Espelage, Dorothy L.; Koenig, Brian

    2009-01-01

    This study tested a social-ecological model of adolescent substance use. Multilevel modeling was used to investigate how systems, such as parents, peers, schools, and communities, directly influence and interact together to influence adolescent substance use. Participants included 14,548 (50.3% female) middle school students who were 78.6% White,…

  19. "Directive approach" for chinese clients receiving psychotherapy: is that really a priority?

    PubMed

    Ng, Chi Ting Connie; James, Susan

    2013-01-01

    The academic literature often suggests that Chinese people prefer directive approaches in therapy. However, studies on this topic are often based on therapists' self-reports: clients' perceptions are rarely considered. What does "directive approach" mean? Is it what clients prefer? Using cultural psychology and medical anthropology as a theoretical framework, the ethnography explored the experience of psychotherapy from Chinese clients' perspectives. Specifically, using ethnographic interview, eight informants, two male and six female, ranging in age from 40 to 55, were interviewed twice in-depth about their experiences of seeing Chinese therapists. All informants are Chinese immigrants who reside in a major Canadian city and saw at least one Chinese therapist in a community counseling agency within 1 year prior to the interview. In the first interview, informants created group of cards describing a list of hypothesized cultural knowledge regarding psychotherapy. After initial data analysis, the cards were presented to the informants in the second interviews, in which they confirmed and/or rejected the hypotheses by grouping, reorganizing, and ranking the cards. In the end each informant created a number of mind-maps with the cards, which served as a representation of informants' psychological reality of psychotherapy based on their ordinary language. The maps were then further analyzed for themes among informants. Results suggest that clients appreciate therapists who "give homework," "analyze their problems," "talk about strategies that other clients have found useful," "chat," and "provide resources." Results also highlight informants' understanding of their own responsibility for the therapeutic relationship which has never been documented before and has important clinical implications.

  20. Directive Approach” for Chinese Clients Receiving Psychotherapy: Is That Really a Priority?

    PubMed Central

    Ng, Chi Ting Connie; James, Susan

    2013-01-01

    The academic literature often suggests that Chinese people prefer directive approaches in therapy. However, studies on this topic are often based on therapists’ self-reports: clients’ perceptions are rarely considered. What does “directive approach” mean? Is it what clients prefer? Using cultural psychology and medical anthropology as a theoretical framework, the ethnography explored the experience of psychotherapy from Chinese clients’ perspectives. Specifically, using ethnographic interview, eight informants, two male and six female, ranging in age from 40 to 55, were interviewed twice in-depth about their experiences of seeing Chinese therapists. All informants are Chinese immigrants who reside in a major Canadian city and saw at least one Chinese therapist in a community counseling agency within 1 year prior to the interview. In the first interview, informants created group of cards describing a list of hypothesized cultural knowledge regarding psychotherapy. After initial data analysis, the cards were presented to the informants in the second interviews, in which they confirmed and/or rejected the hypotheses by grouping, reorganizing, and ranking the cards. In the end each informant created a number of mind-maps with the cards, which served as a representation of informants’ psychological reality of psychotherapy based on their ordinary language. The maps were then further analyzed for themes among informants. Results suggest that clients appreciate therapists who “give homework,” “analyze their problems,” “talk about strategies that other clients have found useful,” “chat,” and “provide resources.” Results also highlight informants’ understanding of their own responsibility for the therapeutic relationship which has never been documented before and has important clinical implications. PMID:23408043

  1. [High-priority research directions in genetics, and the breeding of the sugar beet (Beta vulgaris L.) in the 21st century].

    PubMed

    Kornienko, A V; Podvigina, O A; Zhuzhzhalova, T P; Fedulova, T P; Bogomolov, M A; Oshevnev, V P; Butorina, A K

    2014-11-01

    High-priority research directions for the genetics and breeding of the sugar beet in the 21st century were developed with consideration of the available scientific achievements of domestic and foreign scholars. These directions unite the classical and molecular approaches to solving the problems of increasing the effectiveness of sugar beet breeding carried out on a genetic basis, and they correspond to the contemporary level of scientific research. Seven such directions are proposed.

  2. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5 Table 5 to Part 455 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS PESTICIDE...

  3. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 31 2012-07-01 2012-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5 Table 5 to Part 455 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS...

  4. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5 Table 5 to Part 455 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS PESTICIDE...

  5. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 31 2013-07-01 2013-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5 Table 5 to Part 455 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS...

  6. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 30 2014-07-01 2014-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5 Table 5 to Part 455 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS...

  7. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 31 2012-07-01 2012-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4 to Part 455 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) PESTICIDE...

  8. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 31 2013-07-01 2013-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4... AND STANDARDS (CONTINUED) PESTICIDE CHEMICALS Pt. 455, Table 4 Table 4 to Part 455—BAT and...

  9. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 30 2014-07-01 2014-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4... AND STANDARDS (CONTINUED) PESTICIDE CHEMICALS Pt. 455, Table 4 Table 4 to Part 455—BAT and...

  10. Determination of genotoxic epoxide at trace level in drug substance by direct injection GC/MS.

    PubMed

    Chen, Liqin; Zhang, Wei; Hu, Steven

    2017-08-24

    A novel direct injection gas chromatography method coupled with selective ion monitoring mass spectrometry (GC/SIM-MS) was developed for quantitation of trace levels of high boiling point (HBP) epoxide genotoxic impurity (GTI) in drug substance. The injector temperature was optimized with the aims to minimize matrix effects and enhance SIM signal response. The final injector temperature 160°C was selected after balancing between these two factors. The column screening was conducted as well and MN OPTIMA delta-3 silica capillary column was selected since it showed good peak symmetry without column bleeding. The good linearity was established for the concentration in the range from 0.0045μg/mL to 0.5μg/mL with a R(2)=0.9999. The limit of detection (LOD) and the limit of quantitation (LOQ) were 0.0014μg/mL and 0.0045μg/mL, respectively. The recovery which ranged from 95.0% to 112.5% could meet the ICH acceptance criteria. The validation results demonstrated the good linearity, precision and accuracy of the method which can be further adopted as an adequate quality control tool for quantitation of epoxide impurity at trace levels in drug substance and drug product. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Some new directions for research on psychological interventions for comorbid anxiety and substance use disorders.

    PubMed

    Baillie, Andrew J; Stapinski, Lexine; Crome, Erica; Morley, Kirsten; Sannibale, Claudia; Haber, Paul; Teesson, Maree

    2010-09-01

    Comorbidity between anxiety and substance use disorders is common, yet it is poorly understood and poorly treated. Narrative literature review. PsycINFO and Medline databases were searched for clinical trials of anxiety and substance use disorders using clinical queries for 2005-2009. There are few well-conducted treatment outcome trials for comorbid anxiety and substance use disorders. Some recent (2005-2009) outcome literature has focused on specific mechanisms (anxiety sensitivity and tension reduction alcohol expectancies) that may underlie comorbidity between anxiety and substance use disorders and may lead to more targeted intervention. IMPLICATIONS AND CONCLUSION: The research base for understanding and treating comorbid anxiety and substance use disorders needs to be broadened. In particular research is needed with a focus on: (i) specifying particular comorbid relationships between anxiety and substance use disorders; (ii) the mechanisms that may underlie and maintain those relationships; and (iii) well-conducted evaluations of treatments that target those mechanisms.

  12. Directed funding to address under-provision of treatment for substance use disorders: a quantitative study

    PubMed Central

    2013-01-01

    Background Substance use disorders (SUDs) are a substantial problem in the United States (U.S.), affecting far more people than receive treatment. This is true broadly and within the U.S. military veteran population, which is our focus. To increase funding for treatment, the Veterans Health Administration (VA) has implemented several initiatives over the past decade to direct funds toward SUD treatment, supplementing the unrestricted funds VA medical centers receive. We study the ‘flypaper effect’ or the extent to which these directed funds have actually increased SUD treatment spending. Methods The study sample included all VA facilities and used observational data spanning years 2002 to 2010. Data were analyzed with a fixed effects, ordinary least squares specification with monetized workload as the dependent variable and funding dedicated to SUD specialty clinics the key dependent variable, controlling for unrestricted funding. Results We observed different effects of dedicated SUD specialty clinic funding over the period 2002 to 2008 versus 2009 to 2010. In the earlier period, there is no evidence of a significant portion of the dedicated funding sticking to its target. In the later period, a substantial proportion—38% in 2009 and 61% in 2010—of funding dedicated to SUD specialty clinics did translate into increased medical center spending for SUD treatment. In comparison, only five cents of every dollar of unrestricted funding is spent on SUD treatment. Conclusions Relative to unrestricted funding, dedicated funding for SUD treatment was much more effective in increasing workload, but only in years 2009 and 2010. The differences in those years relative to prior ones may be due to the observed management focus on SUD and SUD-related treatment in the later years. If true, this suggests that in a centrally directed healthcare organization such as the VA, funding dedicated to a service is a necessary, but not sufficient condition for increasing resources

  13. Directed funding to address under-provision of treatment for substance use disorders: a quantitative study.

    PubMed

    Frakt, Austin B; Trafton, Jodie; Wallace, Amy; Neuman, Matthew; Pizer, Steven

    2013-07-18

    Substance use disorders (SUDs) are a substantial problem in the United States (U.S.), affecting far more people than receive treatment. This is true broadly and within the U.S. military veteran population, which is our focus. To increase funding for treatment, the Veterans Health Administration (VA) has implemented several initiatives over the past decade to direct funds toward SUD treatment, supplementing the unrestricted funds VA medical centers receive. We study the 'flypaper effect' or the extent to which these directed funds have actually increased SUD treatment spending. The study sample included all VA facilities and used observational data spanning years 2002 to 2010. Data were analyzed with a fixed effects, ordinary least squares specification with monetized workload as the dependent variable and funding dedicated to SUD specialty clinics the key dependent variable, controlling for unrestricted funding. We observed different effects of dedicated SUD specialty clinic funding over the period 2002 to 2008 versus 2009 to 2010. In the earlier period, there is no evidence of a significant portion of the dedicated funding sticking to its target. In the later period, a substantial proportion--38% in 2009 and 61% in 2010--of funding dedicated to SUD specialty clinics did translate into increased medical center spending for SUD treatment. In comparison, only five cents of every dollar of unrestricted funding is spent on SUD treatment. Relative to unrestricted funding, dedicated funding for SUD treatment was much more effective in increasing workload, but only in years 2009 and 2010. The differences in those years relative to prior ones may be due to the observed management focus on SUD and SUD-related treatment in the later years. If true, this suggests that in a centrally directed healthcare organization such as the VA, funding dedicated to a service is a necessary, but not sufficient condition for increasing resources expended for that service.

  14. Choosing priorities.

    PubMed Central

    Gray, J A

    1979-01-01

    Dr Gray leaves us with a question at the conclusion of his article--how should we choose priorities? He says that the debate so far has been mainly on what we should choose, but perhaps we should consider how to choose even more. Under the various subheadings of Criteria, Principles and Persons Dr Gray sets out the pros and cons of the arguments in the priority debates and tries to offer some more specific guidelines to offset the criticism that the government's priority discussions have been too generalised. Yet this is a difficult task when everyone's priorities are so different. PMID:112252

  15. Peer groups and substance use: examining the direct and interactive effect of leisure activity.

    PubMed

    Thorlindsson, Thorolfur; Bernburg, Jon Gunnar

    2006-01-01

    This paper explores the relationships among adolescent leisure activities, peer behavior, and substance use. We suggest that peer group interaction can have a differential effect on adolescent deviant behavior depending on the type of leisure pattern adolescents engage in. We analyze data from a representative national sample of Icelandic adolescents, exploring the variations in the use of alcohol and illegal drugs among three different patterns of leisure activity, controlling for parental ties and school commitment. The findings show that alcohol and substance use varies significantly across the three leisure patterns. Moreover, it was found that the well-known relationship between adolescent substance use and having substance-using friends is significantly contingent on the type of leisure pattern. Our findings suggest that it is important to take into account different peer leisure activities in order to understand adolescent substance use. Finally, we discuss the implications of the findings for prevention work with adolescents.

  16. Emerging Pharmacologic Treatments for Adolescent Substance Use: Challenges and New Directions

    PubMed Central

    Miranda, Robert; Treloar, Hayley

    2016-01-01

    Adolescence is a key period in the development of substance use and misuse. Substance use typically begins during adolescence and prevalence rates for many substance use disorders peak before age 21 years. Yet, despite clinical demand, treatments for youth rely almost entirely on psychosocial interventions that yield only modest benefit. One potential way to improve treatment effects is to augment the best available psychosocial interventions with pharmacotherapy. Although pharmacotherapy research has advanced care for adults with substance use disorders, no medication is indicated for adolescents and controlled trials with teenagers are scant. Optimizing treatments for youth will require closing this important gap in medication development research. In this paper we review the paucity of pharmacotherapy research for adolescent substance misuse, and we discuss how we can leverage human laboratory paradigms and technology to advance our understanding regarding if and how medications may improve treatment options for youths. PMID:27570728

  17. An example of international drug politics--the development and distribution of substance prevention programs directed at adolescents.

    PubMed

    Lilja, John; Giota, Joanna; Hamilton, David; Larsson, Sam

    2007-01-01

    Many substance use prevention programs directed at adolescents exist that have been developed by researchers in the United States and are intended to be used in school settings. Some of the problems associated with such programs are reviewed, including their accessibility, ease of use, copyright status, evaluation options, program scales, and ratings, together with an overall consideration of the factors and processes posited to be associated with substance use and non-use (posited "at-risk" and "protective" mechanisms). The authors contend that there is a great need to: (a) develop substance use prevention programs which are commercially available but are not protected by copyright, (b) assess empirically each component in a program separately, and (c) encourage funding bodies to be more active in supporting the production of manuals and evaluation instruments for substance use prevention programs directed at adolescents. We need more and better process evaluations that are also sensitive to both endogenous and exogenous forces in order to know the processes by which a successful prevention program achieves its effects, is prevented from doing so and which processes are irrelevant. A social competence framework might be used as both a goal and as a theoretical base to achieve a better understanding of the processes by which substance use prevention programs reach their effects.

  18. An Evaluation of an Hypothesized Paradigm: The Relationship between Childhood Abuse and Substance Use Mediated by Biopsychosocial Factors among Priority Populations.

    ERIC Educational Resources Information Center

    Simons, Loretta N.

    This study evaluated an hypothesized model of biopsychosocial factors that mediate the relationship between childhood abuse and substance abuse. A questionnaire packet consisting of self-report measures was administered to 160 drug dependent participants with and without co-occurring psychological disorders in residential, partial, and outpatient…

  19. [The main directions of improving the system of state accounting and control of radioactive substances and radioactive waste products].

    PubMed

    2012-01-01

    This paper describes a modification of the basic directions of state accounting and control of radioactive substances and radioactive waste products, whose implementation will significantly improve the efficiency of its operation at the regional level. Selected areas are designed to improve accounting and control system for the submission of the enterprises established by the reporting forms, the quality of the information contained in them, as well as structures of information and process for collecting, analyzing and data processing concerning radioactive substances and waste products.

  20. New directions in substance abuse services: programmatic innovations in the Veterans Administration.

    PubMed

    Peterson, K A; Swindle, R W; Moos, R H; Finney, J W; Suchinsky, R T

    1992-01-01

    The purpose of this paper to describe the Department of Veterans Affairs' (VA) recent expansion and enhancement of its substance abuse treatment services. Several treatment innovations are considered from both clinical and administrative perspectives. These services include extended care programs for multiply impaired patients, programs for substance abuse patients with comorbid psychiatry conditions and services designed to improve continuity of care and community re-entry. Emergent themes include a broadening of services to meet the needs of a changing substance abuse population and an emphasis on providing more cost-efficient treatment.

  1. Water quality benchmarking (WQB) and priority control screening (PCS) of persistent toxic substances (PTSs) in China: necessity, method and a case study.

    PubMed

    He, Wei; Qin, Ning; Kong, Xiang-Zhen; Liu, Wen-Xiu; He, Qi-Shuang; Wang, Qing-Mei; Yang, Chen; Jiang, Yu-Jiao; Yang, Bin; Wu, Wen-Jing; Xu, Fu-Liu

    2014-02-15

    The priority control screening (PCS) and water quality benchmarking (WQB) of toxic chemicals in water are key steps to ensure the safety of drinking water and aquatic ecosystem that is the crucial goal of water environment management. Owing to the different levels of social-economic development in different countries and regions, the PCS and WQB of toxic chemicals must be determined in accordance with their specific water environment situations. However, in China, the PCS and WQB of toxic chemicals in water were mainly introduced from the other countries. A method for the PCS and WQB of toxic chemicals in water based on the ecological risks was proposed, and a platform named Bayesian Matbugs Calculator (BMC) was developed. As a case study, the WQB and PCS of sixty-nine PTSs based their ecological risks were performed on the basis of one-year monthly monitoring in Lake Chaohu. The results showed that the current national water quality criteria (WQC) would underestimate the toxicological risk to organisms in this aquatic ecosystem. It appears necessary to develop new WQC for the protection of aquatic organisms in Lake Chaohu. Four grades of priority control chemicals (PCCs) in Lake Chaohu were proposed. The highest priority was assigned to organonitrogen-phosphorus pesticides, including parathion, dichlorvos, malathion, omethoate, and di-n-butyl phthalate. However, the national "blacklist" of toxic compounds only covered 7 of 20 PCCs, indicating that the other 13 PCCs would not be controlled efficiently. Because the pollution pattern of PTSs in various water bodies might be quite different, we appealed to the governments to screen the regional PPC lists or develop a more comprehensive national list for aquatic ecosystem protection in China. Copyright © 2013 Elsevier B.V. All rights reserved.

  2. Substance Use and Mental Health

    MedlinePlus

    ... that addiction to drugs or alcohol is a mental illness? Substance use disorder changes normal desires and priorities. ... had both a substance use disorder and another mental illness. More than half of the people with both ...

  3. Partner Enabling of Substance Use Disorders: Critical Review and Future Directions.

    ERIC Educational Resources Information Center

    Rotunda, Rob J.; Doman, Kathy

    2001-01-01

    Substance use disorders affect not only the identified client but significant others as well. This article contrasts the enabling and codependency constructs, reviews empirical studies of enabling, and offers a conceptualization of partner responses to addiction that could enhance future research efforts and clinical applications in this area. (BF)

  4. Peer Groups and Substance Use: Examining the Direct and Interactive Effect of Leisure Activity

    ERIC Educational Resources Information Center

    Thorlindsson, Thorolfur; Bernburg, Jon Gunnar

    2006-01-01

    This paper explores the relationships among adolescent leisure activities, peer behavior, and substance use. We suggest that peer group interaction can have a differential effect on adolescent deviant behavior depending on the type of leisure pattern adolescents engage in. We analyze data from a representative national sample of Icelandic…

  5. Rationale for a New Direction in Foster Youth Substance Use Disorder Prevention

    PubMed Central

    Braciszewski, Jordan M.; Moore, Roland S.; Stout, Robert L.

    2015-01-01

    Background Of the 463,000 children residing in United States foster care, 29,000 annually exit the system because they have “aged out,” are thus dropped from supportive services, and become responsible for their own housing, finances, and health needs. Given histories of maltreatment, housing instability, and parental substance use, youth preparing to exit care are at substantial risk of developing substance use disorders. Unfortunately, access to services is often limited, both before and after exit from care. Methods With the goal of developing a relevant substance use intervention for these youth, focus groups were conducted with foster care staff, administrators, and parents to assess the feasibility of potential approaches. Results Participants identified several population-specific barriers to delivering adapted intervention models developed for normative populations. They expressed concerns about foster youth developing, then quickly ending, relationships with interventionists, as well as admitting to substance use, given foster care program sanctions for such behavior. Group members stressed the importance of tailoring interventions, using creative, motivational procedures. Conclusions Foster youth seem to encounter unique barriers to receiving adequate care. In light of these results, a novel, engaging approach to overcoming these barriers is also presented. PMID:26229518

  6. Partner Enabling of Substance Use Disorders: Critical Review and Future Directions.

    ERIC Educational Resources Information Center

    Rotunda, Rob J.; Doman, Kathy

    2001-01-01

    Substance use disorders affect not only the identified client but significant others as well. This article contrasts the enabling and codependency constructs, reviews empirical studies of enabling, and offers a conceptualization of partner responses to addiction that could enhance future research efforts and clinical applications in this area. (BF)

  7. Gram-Positive Bacterial Infections: Research Priorities, Accomplishments, and Future Directions of the Antibacterial Resistance Leadership Group.

    PubMed

    Doernberg, Sarah B; Lodise, Thomas P; Thaden, Joshua T; Munita, Jose M; Cosgrove, Sara E; Arias, Cesar A; Boucher, Helen W; Corey, G Ralph; Lowy, Franklin D; Murray, Barbara; Miller, Loren G; Holland, Thomas L

    2017-03-15

    Antimicrobial resistance in gram-positive bacteria remains a challenge in infectious diseases. The mission of the Gram-Positive Committee of the Antibacterial Resistance Leadership Group (ARLG) is to advance knowledge in the prevention, management, and treatment of these challenging infections to improve patient outcomes. Our committee has prioritized projects involving methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) due to the scope of the medical threat posed by these pathogens. Approved ARLG projects involving gram-positive pathogens include (1) a pharmacokinetics/pharmacodynamics study to evaluate the impact of vancomycin dosing on patient outcome in MRSA bloodstream infection (BSI); (2) defining, testing, and validating innovative assessments of patient outcomes for clinical trials of MRSA-BSI; (3) testing new strategies for "step-down" antibiotic therapy for MRSA-BSI; (4) management of staphylococcal BSIs in neonatal intensive care units; and (5) defining the impact of VRE bacteremia and daptomycin susceptibility on patient outcomes. This article outlines accomplishments, priorities, and challenges for research of infections caused by gram-positive organisms.

  8. Advancing American Indian and Alaska Native substance abuse research: current science and future directions.

    PubMed

    Etz, Kathleen E; Arroyo, Judith A; Crump, Aria D; Rosa, Carmen L; Scott, Marcia S

    2012-09-01

    American Indians and Alaska Natives (AI/AN) have disproportionately high rates of substance abuse yet there is little empirical research addressing this significant public health problem. This paper is an introduction to a special issue that includes cutting edge science in this research area. We identify several areas that require consideration in this field and indicate how the papers in the special issue address these gaps. These overarching areas of need, which should be considered in any substantive research, include attention to heterogeneity within the population, research that has tangible health benefits, continued work on research methods and strategies, increased focus on strength based and community oriented approaches, and the need for strong research partnerships. The special issue marks a major step forward for AI/AN substance abuse research. However, articles also highlight where more work is need to improve public health in AI/AN communities by addressing identified gap areas.

  9. Priority Rules.

    ERIC Educational Resources Information Center

    Slear, Tom

    1993-01-01

    Whether speaking of health clinics, budget shortfalls, or discipline issues, Wicomico County (Maryland) School Superintendent Evelyn Holman invariably encases discussions in her own set of priorities. Building student self-esteem through mental health clinics is laudable, but preparing students for college and future employment is foremost.…

  10. Toxicity of seven priority hazardous and noxious substances (HNSs) to marine organisms: Current status, knowledge gaps and recommendations for future research.

    PubMed

    Rocha, A Cristina S; Reis-Henriques, Maria Armanda; Galhano, Victor; Ferreira, Marta; Guimarães, Laura

    2016-01-15

    Shipping industry and seaborne trade have rapidly increased over the last fifty years, mainly due to the continuous increasing demand for chemicals and fuels. Consequently, despite current regulations, the occurrence of accidental spills poses an important risk. Hazardous and noxious substances (HNSs) have been raising major concern among environmental managers and scientific community for their heterogeneity, hazardous potential towards aquatic organisms and associated social-economic impacts. A literature review on ecotoxicological hazards to aquatic organisms was conducted for seven HNSs: acrylonitrile, n-butyl acrylate, cyclohexylbenzene, hexane, isononanol, trichloroethylene and xylene. Information on the mechanisms of action of the selected HNS was also reviewed. The main purpose was to identify: i) knowledge gaps in need of being addressed in future research; and ii) a set of possible biomarkers suitable for ecotoxicological assessment and monitoring in both estuarine and marine systems. Main gaps found concern the scarcity of information available on ecotoxicological effects of HNS towards marine species and their poorly understood mode of action in wildlife. Differences were found between the sensitivity of freshwater and seawater organisms, so endpoints produced in the former may not be straightforwardly employed in evaluations for the marine environment. The relationship between sub-individual effects and higher level detrimental alterations (e.g. behavioural, morphological, reproductive effects and mortality) are not fully understood. In this context, a set of biomarkers associated to neurotoxicity, detoxification and anti-oxidant defences is suggested as potential indicators of toxic exposure/effects of HNS in marine organisms. Overall, to support the development of contingency plans and the establishment of environmental safety thresholds, it will be necessary to undertake targeted research on HNS ecotoxicity in the marine environment. Research should

  11. Setting Priorities for NIOSH Research

    ERIC Educational Resources Information Center

    Gallagher, Richard E.

    1975-01-01

    The National Institute for Occupational Safety and Health (NIOSH) is attempting to develop total programs of occupational safety and health protection. It has established research criteria and a priority system for evaluating the order of investigating suspect substances or agents based upon the expected gain of the health benefit. (Author/MW)

  12. Setting Priorities for NIOSH Research

    ERIC Educational Resources Information Center

    Gallagher, Richard E.

    1975-01-01

    The National Institute for Occupational Safety and Health (NIOSH) is attempting to develop total programs of occupational safety and health protection. It has established research criteria and a priority system for evaluating the order of investigating suspect substances or agents based upon the expected gain of the health benefit. (Author/MW)

  13. Direct and Mediated Effects of a Social-Emotional and Character Development Program on Adolescent Substance Use.

    PubMed

    Lewis, Kendra M; Bavarian, Niloofar; Snyder, Frank J; Acock, Alan; Day, Joseph; Dubois, David L; Ji, Peter; Schure, Marc B; Silverthorn, Naida; Vuchinich, Samuel; Flay, Brian R

    2012-04-01

    Mitigating and preventing substance use among adolescents requires approaches that address the multitude of factors that influence this behavior. Such approaches must be tested, not only for evidence of empirical effectiveness, but also to determine the mechanisms by which they are successful. The aims of the present study were twofold: 1) To determine the effectiveness of a school-based social-emotional and character development (SECD) program, Positive Action (PA), in reducing substance use (SU) among a sample of U.S. youth living in a low-income, urban environment, and 2) to test one mechanism by which the program achieves its success. We used longitudinal mediation analysis to test the hypotheses that: 1) students attending PA intervention schools engage in significantly less SU than students attending control schools, 2) students attending PA intervention schools show significantly better change in SECD than students attending control schools, and 3) the effect of the PA intervention on SU is mediated by the change in SECD. Analyses revealed program effects on both SECD and SU, a relationship between SECD and SU, and the effects of PA on SU were completely mediated by changes in SECD. Future research directions and implications for school-based social-emotional and character development efforts and substance use prevention are addressed.

  14. Direct and Mediated Effects of a Social-Emotional and Character Development Program on Adolescent Substance Use

    PubMed Central

    Lewis, Kendra M.; Bavarian, Niloofar; Snyder, Frank J.; Acock, Alan; Day, Joseph; DuBois, David L.; Ji, Peter; Schure, Marc B.; Silverthorn, Naida; Vuchinich, Samuel; Flay, Brian R.

    2013-01-01

    Mitigating and preventing substance use among adolescents requires approaches that address the multitude of factors that influence this behavior. Such approaches must be tested, not only for evidence of empirical effectiveness, but also to determine the mechanisms by which they are successful. The aims of the present study were twofold: 1) To determine the effectiveness of a school-based social-emotional and character development (SECD) program, Positive Action (PA), in reducing substance use (SU) among a sample of U.S. youth living in a low-income, urban environment, and 2) to test one mechanism by which the program achieves its success. We used longitudinal mediation analysis to test the hypotheses that: 1) students attending PA intervention schools engage in significantly less SU than students attending control schools, 2) students attending PA intervention schools show significantly better change in SECD than students attending control schools, and 3) the effect of the PA intervention on SU is mediated by the change in SECD. Analyses revealed program effects on both SECD and SU, a relationship between SECD and SU, and the effects of PA on SU were completely mediated by changes in SECD. Future research directions and implications for school-based social-emotional and character development efforts and substance use prevention are addressed. PMID:24308013

  15. Substance use disorders in individuals with mild to borderline intellectual disability: current status and future directions.

    PubMed

    van Duijvenbode, Neomi; VanDerNagel, Joanneke E L; Didden, Robert; Engels, Rutger C M E; Buitelaar, Jan K; Kiewik, Marion; de Jong, Cor A J

    2015-03-01

    Knowledge regarding substance use (SU) and substance use disorder (SUD) in individuals with mild to borderline intellectual disabilities (ID) has increased over the last decade, but is still limited. Data on prevalence and risk factors are fragmented, and instruments for screening and assessment and effective treatment interventions are scarce. Also, scientific developments in other fields are insufficiently incorporated in the care for individuals with ID and SUD. In this selective and critical review, we provide an overview of the current status of SU(D) in ID and explore insights on the conceptualisation of SUD from other fields such as addiction medicine and general psychiatry. SU(D) turns out to be a chronic, multifaceted brain disease that is intertwined with other physical, psychiatric and social problems. These insights have implications for practices, policies and future research with regard to the prevalence, screening, assessment and treatment of SUD. We will therefore conclude with recommendations for future research and policy and practice, which may provide a step forward in the care for individuals with ID and SUD.

  16. Biologics to treat substance use disorders: Current status and new directions

    PubMed Central

    Pravetoni, Marco

    2016-01-01

    ABSTRACT Biologics (vaccines, monoclonal antibodies (mAb), and genetically modified enzymes) offer a promising class of therapeutics to treat substance use disorders (SUD) involving abuse of opioids and stimulants such as nicotine, cocaine, and methamphetamine. In contrast to small molecule medications targeting brain receptors, biologics for SUD are larger molecules that do not cross the blood-brain barrier (BBB), but target the drug itself, preventing its distribution to the brain and blunting its effects on the central nervous system (CNS). Active and passive immunization approaches rely on antibodies (Ab) that bind drugs of abuse in serum and block their distribution to the brain, preventing the rewarding effects of drugs and addiction-related behaviors. Alternatives to vaccines and anti-drug mAb are genetically engineered human or bacterial enzymes that metabolize drugs of abuse, lowering the concentration of free active drug. Pre-clinical and clinical data support development of effective biologics for SUD. PMID:27441896

  17. Tools for the prioritization of substances on the Domestic Substances List in Canada on the basis of hazard.

    PubMed

    Hughes, K; Paterson, J; Meek, M E

    2009-12-01

    A precedent setting legislative mandate under the Canadian Environmental Protection Act 1999 to establish priorities for assessment based on systematic consideration of all of the approximately 23,000 Existing Chemicals in Canada required the development and refinement of methodology in a number of important areas. This included development of simple and complex exposure and hazard tools for priority setting which draw maximally and efficiently on available data to systematically identify substances that are highest priorities in relation to their potential to cause adverse effects on the general population. The hierarchical approach in the simple and complex hazard tools described here efficiently and effectively sets substances aside as non-priorities, or prioritizes them for consideration additionally in assessment. The hazard tools efficiently incorporate previous work, contributing to consistency internationally, and involve hierarchical consideration of sources of information based on their relative weighting. They are health protective, based on their incorporated degree of conservatism, and provide direction for additional assessment for substances deemed to be priorities. Although designed for prioritization of Existing Substances in Canada, these tools have potential for broader application in other national and international programs to provide focus and increase efficiency in human health risk assessment.

  18. Direct identification of prohibited substances in cosmetics and foodstuffs using ambient ionization on a miniature mass spectrometry system.

    PubMed

    Ma, Qiang; Bai, Hua; Li, Wentao; Wang, Chao; Li, Xinshi; Cooks, R Graham; Ouyang, Zheng

    2016-03-17

    Significantly simplified work flows were developed for rapid analysis of various types of cosmetic and foodstuff samples by employing a miniature mass spectrometry system and ambient ionization methods. A desktop Mini 12 ion trap mass spectrometer was coupled with paper spray ionization, extraction spray ionization and slug-flow microextraction for direct analysis of Sudan Reds, parabens, antibiotics, steroids, bisphenol and plasticizer from raw samples with complex matrices. Limits of detection as low as 5 μg/kg were obtained for target analytes. On-line derivatization was also implemented for analysis of steroid in cosmetics. The developed methods provide potential analytical possibility for outside-the-lab screening of cosmetics and foodstuff products for the presence of illegal substances. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Removal program priorities

    SciTech Connect

    Not Available

    1988-03-31

    The directive contains general policy guidelines regarding removal program priorities as it specifically relates to the 10 regional offices. Emphasis is placed on addressing the most serious public health and environmental threats (classic emergencies, time-critical removals at NPL sites, and time-critical removals at non-NPL sites). Regions are urged to pursue cleanup by the responsible parties (RP) and manage the removal program within the boundaries of their resources.

  20. Your Health Priorities Tool

    MedlinePlus

    ... Care Explore Your Treatment Options: Your Health Priorities Tool Home Why Explore Your Options Start the Conversation ... Home > Your Health Priorities Tool Your Health Priorities Tool If you don’t share details about your ...

  1. The Direct and Indirect Effects of Parental Bonds, Parental Drug Use, and Self-Control on Adolescent Substance Use

    ERIC Educational Resources Information Center

    Hope,Trina L.; Whiteford, Scott W.

    2005-01-01

    Research indicates that parenting has important effects on adolescent substance use. However, the indirect effect of parenting on adolescent substance use via self-control is less understood. Gottfredson and Hirschi's General Theory of Crime has been extensively tested by researchers in the field of criminology, but the theory rarely has been used…

  2. The Direct and Indirect Effects of Parental Bonds, Parental Drug Use, and Self-Control on Adolescent Substance Use

    ERIC Educational Resources Information Center

    Hope,Trina L.; Whiteford, Scott W.

    2005-01-01

    Research indicates that parenting has important effects on adolescent substance use. However, the indirect effect of parenting on adolescent substance use via self-control is less understood. Gottfredson and Hirschi's General Theory of Crime has been extensively tested by researchers in the field of criminology, but the theory rarely has been used…

  3. Evidence for direct cellular protective effect of PL-10 substances (synthesized parts of body protection compound, BPC) and their specificity to gastric mucosal cells.

    PubMed

    Bódis, B; Karádi, O; Németh, P; Dohoczky, C; Kolega, M; Mózsik, G

    1997-01-01

    The direct gastric mucosal cellular effect of four PL-10 substances (a synthesized part of human body protection compound, BPC containing 14 or 15 amino acids) was studied on freshly isolated rat gastric mucosal cells and on a mouse myeloma cell line (Sp2/0-Ag14) in an ethanol-induced cell injury model. The examined substances were not toxic for the cells. Two of them proved to be significantly protective against the direct cellular damaging effect of ethanol (PL 10.1.15AK-3 in 5 microg/ml dose and PL 10.1.AK14-2 dose-dependently, ED50=50 ng/ml) on gastric mucosal cells. This cytoprotective effect was failured on mouse myeloma cells. Based on these results a part of the in vivo protection induced by BPC seems to be a direct cellular protective effect to gastric mucosal cells.

  4. Other- and Self-Directed Forms of Violence and Their Relationships to DSM-IV Substance Use and Other Psychiatric Disorders in a National Survey of Adults

    PubMed Central

    Harford, Thomas C.; Yi, Hsiao-ye; Grant, Bridget F.

    2013-01-01

    Objective To examine associations between DSM-IV psychiatric disorders and other- and self- directed violence in the general population. Methods Data were obtained from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Waves 1 & 2 (n=34,653). Four violence categories were derived from a latent class analysis (LCA) of 5 other-directed and 4 self-directed violent behavior indicators. Multinomial logistic regression examined class associations for gender, race-ethnicity, age and DSM-IV substance use, mood, anxiety, and personality disorders. Results Approximately 16% of adults reported some form of violent behavior distributed as follows: other-directed only, 4.6%; self-directed only, 9.3%; combined self- and other-directed, 2.0%; and no violence, 84.1%. The majority of the DSM-IV disorders included in this study were significantly and independently related to each form of violence. Generally, other-directed violence was more strongly associated with any substance use disorders (81%) and any personality disorders (42%), while self-directed violence was more strongly associated with mood (41%) and anxiety disorders (57%). Compared with these two forms of violence, the smaller group with combined self- and other-directed violence was more strongly associated with any substance use disorders (88%), mood disorders (63%), and personality disorders (76%). Conclusion Findings from this study are consistent with recent conceptualizations of disorders as reflecting externalizing disorders and internalizing disorders. The identification of the small category with combined forms of violence further extends numerous clinical studies which established associations between self- and other-directed violent behaviors. The extent to which the combined violence category represents a meaningful and reliable category of violence requires further detailed studies. PMID:23587529

  5. Other- and self-directed forms of violence and their relationships to DSM-IV substance use and other psychiatric disorders in a national survey of adults.

    PubMed

    Harford, Thomas C; Yi, Hsiao-Ye; Grant, Bridget F

    2013-10-01

    To examine associations between DSM-IV psychiatric disorders and other- and self-directed violence in the general population. Data were obtained from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Waves 1 & 2 (n=34,653). Four violence categories were derived from a latent class analysis (LCA) of 5 other-directed and 4 self-directed violent behavior indicators. Multinomial logistic regression examined class associations for gender, race-ethnicity, age and DSM-IV substance use, mood, anxiety, and personality disorders. Approximately 16% of adults reported some form of violent behavior distributed as follows: other-directed only, 4.6%; self-directed only, 9.3%; combined self- and other-directed, 2.0%; and no violence, 84.1%. The majority of the DSM-IV disorders included in this study were significantly and independently related to each form of violence. Generally, other-directed violence was more strongly associated with any substance use disorders (81%) and any personality disorders (42%), while self-directed violence was more strongly associated with mood (41%) and anxiety disorders (57%). Compared with these two forms of violence, the smaller group with combined self- and other-directed violence was more strongly associated with any substance use disorders (88%), mood disorders (63%), and personality disorders (76%). Findings from this study are consistent with recent conceptualizations of disorders as reflecting externalizing disorders and internalizing disorders. The identification of the small category with combined forms of violence further extends numerous clinical studies which established associations between self- and other-directed violent behaviors. The extent to which the combined violence category represents a meaningful and reliable category of violence requires further detailed studies. Copyright © 2013 Elsevier Inc. All rights reserved.

  6. The atomic-scale unit, entity: key to a direct and easily understood definition of the SI base unit for amount of substance

    NASA Astrophysics Data System (ADS)

    Leonard, B. P.

    2007-10-01

    The atomic-scale unit, entity (ent), is defined as the number-specific amount of substance, n/N, the amount of substance of a single entity. This unit is an invariant physical quantity (the reciprocal of the Avogadro constant) that serves as the basis for redefining the SI base unit for amount of substance in a direct and easily understood manner. It is argued here that the kilomole should be the base unit in order to avoid factors of 10-3 or 103 appearing in relationships involving both mass and amount of substance expressed in base units. Since, in a compatible formulation, the amount-specific number of entities, N/n (= NA), is equal to Mu/Da, exactly, where Mu = kg kmol-1 = g mol-1 = Da ent-1, exactly, then NA = (kg/Da) kmol-1 = (g/Da) mol-1 = 1 ent-1, exactly. The kilomole can thus be defined very simply as: kmol = \\cal N^{\\ast}\\,ent , exactly, where \\cal N^{\\ast} , the exact kilomole-to-entity amount ratio, is identical to the kilogram-to-dalton mass ratio: \\cal N^{\\ast} \\equiv kmol/ent\\equiv kg/Da . The Avogadro constant, N_A = \\cal N^{\\ast}\\,kmol^{-1} , does not appear explicitly in the defining equation, its reciprocal having been replaced by one entity. Like the dalton, the entity would be categorized as a unit in use with SI.

  7. Priority arbitration mechanism

    DOEpatents

    Garmire, Derrick L.; Herring, Jay R.; Stunkel, Craig B.

    2007-03-06

    A method is provided for selecting a data source for transmission on one of several logical (virtual) lanes embodied in a single physical connection. Lanes are assigned to either a high priority class or to a low priority class. One of six conditions is employed to determine when re-arbitration of lane priorities is desired. When this occurs a next source for transmission is selected based on a the specification of the maximum number of high priority packets that can be sent after a lower priority transmission has been interrupted. Alternatively, a next source for transmission is selected based on a the specification of the maximum number of high priority packets that can be sent while a lower priority packet is waiting. If initialized correctly, the arbiter keeps all of the packets of a high priority packet contiguous, while allowing lower priority packets to be interrupted by the higher priority packets, but not to the point of starvation of the lower priority packets.

  8. Social Priorities as Data

    NASA Astrophysics Data System (ADS)

    Grubert, E.

    2015-12-01

    Decision makers' responses to local risks and expected changes to a community from circumstances like natural hazards, human developments, and demographic changes can greatly affect social and environmental outcomes in a community. Translating physical data based in disciplines like engineering and geosciences into positive outcomes for communities can be challenging and often results in conflict that appears to pit "science" against "the public." Scientists can be reluctant to offer recommendations for action based on their work, often (and often correctly) noting that their role is not to make value judgments for a community - particularly for a community that is not their own. Conversely, decision makers can be frustrated by the lack of guidance they receive to help translate data into effective and acceptable action. The solution posed by this submission, given the goal of co-production of knowledge by scientists and decision makers to foster better community outcomes, is to involve the community directly by integrating social scientific methods that address decision making and community engagement to the scientist-decision maker interaction. Specifically, the missing dataset in many scientist-decision maker interactions is the nature of community priorities. Using scientifically valid methods to rigorously collect and characterize community priorities to help recommend tradeoffs between different outcomes indicated by the work of physical and natural scientists can bridge the gap between science and action by involving the community in the process. This submission presents early work on US preferences for different types of social and environmental outcomes designed to integrate directly with engineering and physical science frameworks like Life Cycle Assessment and Environmental Impact Statements. Cardinal preference data are based on surveys of US adults using tools like the Analytical Hierarchy Process, budget allocation, and ranking.

  9. A primer on potential impacts, management priorities, and future directions for Elodea spp. in high latitude systems: learning from the Alaskan experience

    USGS Publications Warehouse

    Carey, Michael P.; Sethi, Suresh A; Larsen, Sabrina J; Rich, Cecil F

    2016-01-01

    Invasive species introductions in Arctic and Subarctic ecosystems are growing as climate change manifests and human activity increases in high latitudes. The aquatic plants of the genus Elodea are potential invaders to Arctic and Subarctic ecosystems circumpolar and at least one species is already established in Alaska, USA. To illustrate the problems of preventing, eradicating, containing, and mitigating aquatic, invasive plants in Arctic and Subarctic ecosystems, we review the invasion dynamics of Elodea and provide recommendations for research and management efforts in Alaska. Foremost, we conclude the remoteness of Arctic and Subarctic systems such as Alaska is no longer a protective attribute against invasions, as transportation pathways now reach throughout these regions. Rather, high costs of operating in remote Arctic and Subarctic systems hinders detection of infestations and limits eradication or mitigation, emphasizing management priorities of prevention and containment of aquatic plant invaders in Alaska and other Arctic and Subarctic systems.

  10. Global health priorities - priorities of the wealthy?

    PubMed

    Ollila, Eeva

    2005-04-22

    Health has gained importance on the global agenda. It has become recognized in forums where it was once not addressed. In this article three issues are considered: global health policy actors, global health priorities and the means of addressing the identified health priorities. I argue that the arenas for global health policy-making have shifted from the public spheres towards arenas that include the transnational for-profit sector. Global health policy has become increasingly fragmented and verticalized. Infectious diseases have gained ground as global health priorities, while non-communicable diseases and the broader issues of health systems development have been neglected. Approaches to tackling the health problems are increasingly influenced by trade and industrial interests with the emphasis on technological solutions.

  11. Subsurface flow and transport of organic chemicals: an assessment of current modeling capability and priority directions for future research (1987-1995)

    SciTech Connect

    Streile, G.P.; Simmons, C.S.

    1986-09-01

    Theoretical and computer modeling capability for assessing the subsurface movement and fate of organic contaminants in groundwater was examined. Hence, this study is particularly concerned with energy-related, organic compounds that could enter a subsurface environment and move as components of a liquid phase separate from groundwater. The migration of organic chemicals that exist in an aqueous dissolved state is certainly a part of this more general scenario. However, modeling of the transport of chemicals in aqueous solution has already been the subject of several reviews. Hence, this study emphasizes the multiphase scenario. This study was initiated to focus on the important physicochemical processes that control the behavior of organic substances in groundwater systems, to evaluate the theory describing these processes, and to search for and evaluate computer codes that implement models that correctly conceptualize the problem situation. This study is not a code inventory, and no effort was made to identify every available code capable of representing a particular process.

  12. Priorities for the Priority Review Voucher

    PubMed Central

    Ridley, David B.

    2017-01-01

    The U.S. Congress created the priority review voucher program in 2007 to encourage development of drugs for neglected diseases. Under the voucher program, the developer of a drug for a neglected or rare pediatric disease that is approved by the U.S. Food and Drug Administration receives a bonus priority review voucher for another drug. As of 2016, four vouchers have sold for an average price of $200 million. Recent experience with the voucher program indicates strengths and weaknesses of the program, as well as a need for legislative changes. PMID:27573624

  13. Review of substance use disorder treatment research in Indian country: future directions to strive toward health equity.

    PubMed

    Greenfield, Brenna L; Venner, Kamilla L

    2012-09-01

    American Indians and Alaska Natives (AI/ANs) have disproportionately high rates of substance use disorders (SUDs). Effective treatment can help to reduce these disparities. To review and summarize the AI/AN SUD treatment research literature. The literature between 1965 and 2011 was reviewed to identify AI/AN SUD treatment articles. Twenty-four unique studies were identified. Earlier treatment research focused on clinical ratings of improvement; later studies employed formal assessment measures. Poor outcomes were attributed to psychosocial factors. Where treatment outcomes appeared to be similar to comparison samples, interpretation was hampered by methodological concerns. The research has improved across the decades, as has the inclusion of cultural adaptations. Future research should examine factors that influence treatment effectiveness and improve retention to bolster confidence in findings. AI/ANs experience SUD-related health disparities. Understanding what factors contribute to positive treatment outcomes can help to address these disparities.

  14. Psychiatric diagnoses, mental health utilization, high-risk behaviors, and self-directed violence among veterans with comorbid history of traumatic brain injury and substance use disorders.

    PubMed

    Olson-Madden, Jennifer H; Forster, Jeri E; Huggins, Joseph; Schneider, Alexandra

    2012-01-01

    To describe various characteristics of veterans with co-occurring histories of traumatic brain injury (TBI) and substance use disorder (SUD) for purposes of hypothesis generation. Archival data collected over a period of 4 years. Sixty-five veterans across eras of service with confirmed histories of TBI and SUD. : Demographic and TBI information were obtained from an archival clinical database. Electronic medical records were reviewed for mental health utilization, psychiatric diagnoses, self-directed violence, and risk-taking behaviors. In addition to a SUD, veterans were reported to have an average of 3 additional psychiatric diagnoses and a median of 3 TBIs per person. All utilized various mental health services in addition to substance use treatment. Individuals were found to have engaged in a variety of risky behaviors. There were significant associations between suicidal ideation and assaultive behaviors, as well as between suicide attempt and impulsivity. This study describes a sample of veterans with co-occurring histories of TBI, SUD, risk-taking behaviors, and self-directed violence. More research is needed to examine these complex interrelationships and to identify specific risk factors for intervention/prevention strategies.

  15. Prioritization of therapy uncertainties in Dystrophic Epidermolysis Bullosa: where should research direct to? an example of priority setting partnership in very rare disorders

    PubMed Central

    2013-01-01

    Background Dystrophic Epidermolysis Bullosa (DEB) is a rare genodermatosis (7 cases per million) that causes blisters and erosions with minor trauma in skin and mucosa, and other systemic complications. A recently updated systematic review showed that the research evidence about DEB therapies is poor. As new trials in DEB are difficult and expensive, it is important to prioritizise research that patients and clinicians consider more relevant. Objectives To describe and prioritize the most important uncertainties about DEB treatment shared by patients, carers and health care professionals (HCPs) in order to promote research in those areas. Methods A DEB Priority Setting Partnership (PSP) was established, including patients, carers and HCPs. DBE uncertainties were gathered from patients and clinicians, and prioritized in a transparent process, using the methodology advocated by the James Lind Alliance. Results In the consultation stage, 323 uncertainties were submitted by 58 participants. Once the duplicated and non-treatment uncertainties were removed, the remainder were reduced to a list of 24 most voted questions. These 24 uncertainties were prioritized in a final workshop where a balanced number of patients, carers and HCPs selected the top 10 therapy uncertainties. The final list includes interventions in wound care, itch and pain management, treatment and prevention of syndactyly, cancer prevention and future promising therapies. Conclusions The final list of the top 10 treatment uncertainties on the management of DEB provides guidance for researchers and funding bodies, to ensure that future research answers questions that are important to both clinicians and patients. The method proposed by the James Lind Alliance is feasible for very rare disorders. PMID:23607806

  16. Prioritization of therapy uncertainties in Dystrophic Epidermolysis Bullosa: where should research direct to? an example of priority setting partnership in very rare disorders.

    PubMed

    Davila-Seijo, Paula; Hernández-Martín, Angela; Morcillo-Makow, Evanina; de Lucas, Raúl; Domínguez, Esther; Romero, Natividad; Monrós, Eva; Feito, Marta; Carretero, Luis; Aranegui, Bea; García-Doval, Ignacio

    2013-04-22

    Dystrophic Epidermolysis Bullosa (DEB) is a rare genodermatosis (7 cases per million) that causes blisters and erosions with minor trauma in skin and mucosa, and other systemic complications. A recently updated systematic review showed that the research evidence about DEB therapies is poor. As new trials in DEB are difficult and expensive, it is important to prioritizise research that patients and clinicians consider more relevant. To describe and prioritize the most important uncertainties about DEB treatment shared by patients, carers and health care professionals (HCPs) in order to promote research in those areas. A DEB Priority Setting Partnership (PSP) was established, including patients, carers and HCPs. DBE uncertainties were gathered from patients and clinicians, and prioritized in a transparent process, using the methodology advocated by the James Lind Alliance. In the consultation stage, 323 uncertainties were submitted by 58 participants. Once the duplicated and non-treatment uncertainties were removed, the remainder were reduced to a list of 24 most voted questions. These 24 uncertainties were prioritized in a final workshop where a balanced number of patients, carers and HCPs selected the top 10 therapy uncertainties. The final list includes interventions in wound care, itch and pain management, treatment and prevention of syndactyly, cancer prevention and future promising therapies. The final list of the top 10 treatment uncertainties on the management of DEB provides guidance for researchers and funding bodies, to ensure that future research answers questions that are important to both clinicians and patients. The method proposed by the James Lind Alliance is feasible for very rare disorders.

  17. Priorities for Extension.

    ERIC Educational Resources Information Center

    Hayward, J. A.

    Agricultural extension is one component in an array including research, training, education, marketing, international trade, etc. which develop together to bring about growth, and sustained growth determines the priorities for extension. These priorities depend inevitably on the stage of development of a country or region, and on the current…

  18. Priority in Process Algebras

    NASA Technical Reports Server (NTRS)

    Cleaveland, Rance; Luettgen, Gerald; Natarajan, V.

    1999-01-01

    This paper surveys the semantic ramifications of extending traditional process algebras with notions of priority that allow for some transitions to be given precedence over others. These enriched formalisms allow one to model system features such as interrupts, prioritized choice, or real-time behavior. Approaches to priority in process algebras can be classified according to whether the induced notion of preemption on transitions is global or local and whether priorities are static or dynamic. Early work in the area concentrated on global pre-emption and static priorities and led to formalisms for modeling interrupts and aspects of real-time, such as maximal progress, in centralized computing environments. More recent research has investigated localized notions of pre-emption in which the distribution of systems is taken into account, as well as dynamic priority approaches, i.e., those where priority values may change as systems evolve. The latter allows one to model behavioral phenomena such as scheduling algorithms and also enables the efficient encoding of real-time semantics. Technically, this paper studies the different models of priorities by presenting extensions of Milner's Calculus of Communicating Systems (CCS) with static and dynamic priority as well as with notions of global and local pre- emption. In each case the operational semantics of CCS is modified appropriately, behavioral theories based on strong and weak bisimulation are given, and related approaches for different process-algebraic settings are discussed.

  19. Characterizing direct emissions of perfluoroalkyl substances from ongoing fluoropolymer production sources: A spatial trend study of Xiaoqing River, China.

    PubMed

    Shi, Yali; Vestergren, Robin; Xu, Lin; Song, Xiaowei; Niu, Xiameng; Zhang, Chunhui; Cai, Yaqi

    2015-11-01

    The spatial trend of perfluoroalkyl substances (PFASs) along Xiaoqing River and its tributaries was studied to characterize isomer profiles and quantify emissions from fluoropolymer (FP) manufacturers in China. Substantially elevated ∑PFAS concentrations downstream of tributary 4 demonstrated that the emissions from this FP manufacturer dominated total riverine discharges. Isomer profiles of perfluorooctanoic acid (PFOA) in water displayed a stepwise increase in percentage branched PFOA downstream of tributary 3 (14.0%) and 4 (22.7%) reflecting the importance of FP sources. Strong positive correlations between PFOA isomers in water downstream of tributary 4 indicated that isomer profiles were conserved from emission sources to the final reservoir. Riverine discharges of PFOA (23-67 t/yr) were in agreement with theoretical emission calculations from FP production (68 t/yr) whereas large discrepancies between the two methodologies were observed for perfluorobutanoic acid and perfluoropentanoic acid. Collectively, this study fills critical knowledge gaps for understanding ongoing global sources of PFASs.

  20. Selective determination of dimenhydrinate in presence of six of its related substances and potential impurities using a direct GC/MS method

    PubMed Central

    Belal, Tarek S.; Abdel-Hay, Karim M.; Clark, C. Randall

    2015-01-01

    A novel simple, direct and selective gas chromatography–mass spectrometry (GC/MS) procedure was developed for the determination of the antihistamine drug dimenhydrinate (DMH) in presence of six of its related substances and potential impurities, namely, diphenylmethane, diphenylmethanol, benzophenone, orphenadrine, caffeine and 8-chlorocaffeine. The method involved resolution of the underivatized compounds using a trifluoropropylmethyl polysiloxane (Rtx-200) capillary column and the mass spectrometric detection was carried out in the electron-impact (EI) mode. Excellent baseline separation of DMH and the cited related substances was achieved in less than 15 min. Quantification of the parent drug DMH was based on measuring its peak area. The reliability and analytical performance of the proposed method were validated with respect to linearity, range, precision, accuracy, specificity, robustness, detection and quantification limits. Calibration curve of DMH was linear over the range 50–500 μg/mL with determination coefficient (R2) = 0.9982. The proposed method was successfully applied for the assay of DMH in tablets dosage form with recoveries >96.80%. PMID:26843970

  1. Cigarette smoking in pregnant substance users: Association with substance use and desire to quit.

    PubMed

    Winhusen, Theresa; Lewis, Daniel

    2017-01-01

    Cigarette smoking is prevalent in pregnant substance users but receives low priority in substance use disorder treatment. This article reports the results of a secondary analysis of a randomized, multisite trial with 200 pregnant substance users, 145 (72.5%) of whom smoked at baseline. As predicted: (1) smokers had significantly greater substance use; (2) approximately half of smokers wanted to quit; and (3) smokers with a quit goal had significantly greater self-efficacy and lower perceived difficulty of quitting. Smoking may be associated with more severe substance use in pregnant substance-using patients, half of whom may be interested in smoking-cessation interventions.

  2. Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions.

    PubMed

    Becker, Sara J

    2015-03-01

    The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers as a complementary approach to existing dissemination efforts. Specific issues discussed include: rationale for DTC marketing based on the concept of push versus pull marketing; overview of key stakeholders involved in DTC marketing; and description of the Marketing Mix planning framework. The applicability of these issues to the dissemination of EBP for M/SU is discussed.

  3. Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions

    PubMed Central

    Becker, Sara J.

    2014-01-01

    The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers as a complementary approach to existing dissemination efforts. Specific issues discussed include: rationale for DTC marketing based on the concept of push versus pull marketing; overview of key stakeholders involved in DTC marketing; and description of the Marketing Mix planning framework. The applicability of these issues to the dissemination of EBP for M/SU is discussed. PMID:25937710

  4. Setting conservation priorities.

    PubMed

    Wilson, Kerrie A; Carwardine, Josie; Possingham, Hugh P

    2009-04-01

    A generic framework for setting conservation priorities based on the principles of classic decision theory is provided. This framework encapsulates the key elements of any problem, including the objective, the constraints, and knowledge of the system. Within the context of this framework the broad array of approaches for setting conservation priorities are reviewed. While some approaches prioritize assets or locations for conservation investment, it is concluded here that prioritization is incomplete without consideration of the conservation actions required to conserve the assets at particular locations. The challenges associated with prioritizing investments through time in the face of threats (and also spatially and temporally heterogeneous costs) can be aided by proper problem definition. Using the authors' general framework for setting conservation priorities, multiple criteria can be rationally integrated and where, how, and when to invest conservation resources can be scheduled. Trade-offs are unavoidable in priority setting when there are multiple considerations, and budgets are almost always finite. The authors discuss how trade-offs, risks, uncertainty, feedbacks, and learning can be explicitly evaluated within their generic framework for setting conservation priorities. Finally, they suggest ways that current priority-setting approaches may be improved.

  5. Evaluating whether direct-to-consumer marketing can increase demand for evidence-based practice among parents of adolescents with substance use disorders: rationale and protocol.

    PubMed

    Becker, Sara J

    2015-02-10

    Fewer than one in 10 adolescents with substance use disorders (ASUDs) will receive specialty treatment, and even fewer will receive treatment designated as evidence-based practice (EBP). Traditional efforts to increase the utilization of EBP by ASUDs typically focus on practitioners-either in substance use clinics or allied health settings. Direct-to-consumer (DTC) marketing that directly targets parents of ASUDs represents a potentially complementary paradigm that has yet to be evaluated. The current study is the first to evaluate the relevance of a well-established marketing framework (the Marketing Mix) and measurement approach (measurement of perceived service quality [PSQ]) with parents of ASUDs in need of treatment. A mixed-methods design is employed across three study phases, consistent with well-established methods used in the field of marketing science. Phase 1 consists of formative qualitative research with parents (and a supplementary sample of adolescents) in order to evaluate and potentially adapt a conceptual framework (Marketing Mix) and measure of PSQ. Phase 2 is a targeted survey of ASUD parents to elucidate their marketing preferences, using the adapted Marketing Mix framework, and to establish the psychometric properties of the PSQ measure. The survey will also gather data on parents' preferences for different targeted marketing messages. Phase 3 is a two-group randomized controlled trial comparing the effectiveness of targeted marketing messages versus standard clinical information. Key outcomes will include parents' ratings of PSQ (using the new measure), behavioral intentions to seek out information about EBP, and actual information-seeking behavior. The current study will inform the field whether a well-established marketing framework and measurement approach can be used to increase demand for EBP among parents of ASUDs. Results of this study will have the potential to immediately inform DTC marketing efforts by professional organizations

  6. Aquatic risk assessment of priority and other river basin specific pesticides in surface waters of Mediterranean river basins.

    PubMed

    Silva, Emília; Daam, Michiel A; Cerejeira, Maria José

    2015-09-01

    To meet good chemical and ecological status, Member States are required to monitor priority substances and chemicals identified as substances of concern at European Union and local/river-basin/national level, respectively, in surface water bodies, and to report exceedances of the environmental quality standards (EQSs). Therefore, standards have to be set at national level for river basin specific pollutants. Pesticides used in dominant crops of several agricultural areas within the catchment of Mediterranean river basins ('Mondego', 'Sado' and 'Tejo', Portugal) were selected for monitoring, in addition to the pesticides included in priority lists defined in Europe. From the 29 pesticides and metabolites selected for the study, 20 were detected in surface waters of the river basins, seven of which were priority substances: alachlor, atrazine, chlorfenvinphos, chlorpyrifos, endosulfan, simazine and terbutryn, all of which exceeded their respective EQS values. QSs for other specific pollutants were calculated using different extrapolation techniques (i.e. deterministic or probabilistic) largely based on the method described in view of the Water Framework Directive. Non-acceptable aquatic risks were revealed for molinate, oxadiazon, pendimethalin, propanil, terbuthylazine, and the metabolite desethylatrazine. Implications of these findings for the classification of the ecological status of surface water bodies in Portugal and at the European level are discussed.

  7. Features of the Italian National Inventory of Chemical Substances.

    PubMed

    Binetti, R; Marcello, I

    1994-01-01

    The Italian National Inventory of Chemical Substances (Inventario nazionale delle sostanze chimiche, INSC), a factual data bank on chemical toxicology produced by the Istituto Superiore di Sanità (ISS), consists of a computerized system on existing chemicals developed for routinary and emergency needs. Historical background, current status and future direction of INSC are discussed. The structure and the feature of INSC are briefly examined. Aspects of retrieval of information and the criteria for the inclusion of data and priority selection are also considered.

  8. Finding Novel Antibiotic Substances from Medicinal Plants – Antimicrobial Properties of Nigella Sativa Directed against Multidrug-resistant Bacteria

    PubMed Central

    Bakal, Seher Nancy; Bereswill, Stefan; Heimesaat, Markus M.

    2017-01-01

    The progressive rise in multidrug-resistant (MDR) bacterial strains poses serious problems in the treatment of infectious diseases. While the number of newly developed antimicrobial compounds has greatly fallen, the resistance of pathogens against commonly prescribed drugs is further increasing. This rise in resistance illustrates the need for developing novel therapeutic and preventive antimicrobial options. The medicinal herb Nigella sativa and its derivatives constitute promising candidates. In a comprehensive literature survey (using the PubMed data base), we searched for publications on the antimicrobial effects of N. sativa particularly directed against MDR bacterial strains. In vitro studies published between 2000 and 2015 revealed that N. sativa exerted potent antibacterial effects against both Gram-positive and Gram-negative species including resistant strains. For instance, N. sativa inhibited the growth of bacteria causing significant gastrointestinal morbidity such as Salmonella, Helicobacter pylori, and Escherichia coli. However, Listeria monocytogenes and Pseudomonas aeruginosa displayed resistance against black cumin seed extracts. In conclusion, our literature survey revealed potent antimicrobial properties of N. sativa against MDR strains in vitro that should be further investigated in order to develop novel therapeutic perspectives for combating infectious diseases particularly caused by MDR strains. PMID:28386474

  9. Finding Novel Antibiotic Substances from Medicinal Plants - Antimicrobial Properties of Nigella Sativa Directed against Multidrug-resistant Bacteria.

    PubMed

    Bakal, Seher Nancy; Bereswill, Stefan; Heimesaat, Markus M

    2017-03-01

    The progressive rise in multidrug-resistant (MDR) bacterial strains poses serious problems in the treatment of infectious diseases. While the number of newly developed antimicrobial compounds has greatly fallen, the resistance of pathogens against commonly prescribed drugs is further increasing. This rise in resistance illustrates the need for developing novel therapeutic and preventive antimicrobial options. The medicinal herb Nigella sativa and its derivatives constitute promising candidates. In a comprehensive literature survey (using the PubMed data base), we searched for publications on the antimicrobial effects of N. sativa particularly directed against MDR bacterial strains. In vitro studies published between 2000 and 2015 revealed that N. sativa exerted potent antibacterial effects against both Gram-positive and Gram-negative species including resistant strains. For instance, N. sativa inhibited the growth of bacteria causing significant gastrointestinal morbidity such as Salmonella, Helicobacter pylori, and Escherichia coli. However, Listeria monocytogenes and Pseudomonas aeruginosa displayed resistance against black cumin seed extracts. In conclusion, our literature survey revealed potent antimicrobial properties of N. sativa against MDR strains in vitro that should be further investigated in order to develop novel therapeutic perspectives for combating infectious diseases particularly caused by MDR strains.

  10. Direction and magnitude of change in soil use for a wetland area in Chile: Puren marshes, a priority site for biodiversity conservation (stage 1).

    NASA Astrophysics Data System (ADS)

    Sepúlveda-Varas, Alejandra

    2014-05-01

    Land managers and policymakers need information about soil change caused by anthropogenic and non-anthropogenic factors to predict the effects of management on soil function, compare alternatives, and make decisions. This is particularly relevant in highly fragile ecosystems such as wetlands or humid systems. The wetlands require the presence of three key components: hydric soils, hydrophytic vegetation and wetland hydrology. Therefore, the presence of hydric soils in humid systems is essential for the existence of a wetland. In Chile, one of the geographic zones with the greatest diversity of humid systems is the coast of the Araucanía Region, which contains one of the largest and most threatened humid systems of the region, Puren Marshes, whose soils are only generically described as alluvial terraces and miscellaneous swamp. In this area, studies have reported a high intensity of anthropogenic activity, generating soil erosion, loss of wetland coverage and landscape alteration. For this first stage of a main investigation about the vulnerability of hydric soils to changes in patterns of soil use, the objective was to characterize the variables of soil use in the Puren Marshes and determinate the direction and magnitude of change in soil use in the study area for the period between 1994 and 2007 (the official reports indicate that until 1994, the total area of Puren Marshes was 1147 ha). For the analyses, were used official reports of soil use, the coverages were obtained from the project map databases "Catastro y Evaluación de los Recursos Vegetacionales Nativos de Chile" 1993 and its update for La Araucanía, Regional Government of La Araucanía 2011, DMF CONAF 2010 and IGM 2007. The map information was processed in ARCGIS 9.3.1 software under UTM coordinates, datum WGS 84 and 18 South Time extended. Was developed a multitemporal analysis by construction of transition matrix and confusion matrix. The results obtained show that for the period analysed, the

  11. Transport of lucifer yellow CH into plant vacuoles--evidence for direct energization of a sulphonated substance and implications for the design of new molecular probes.

    PubMed

    Klein, M; Martinoia, E; Weissenböck, G

    1997-12-22

    Contrasting observations exist which indicate that in plants the fluorescent dye lucifer yellow CH (LYCH) either can be used as a tracer for endocytosis or as a substrate for an anion transporter located at the vacuolar membrane. In addition, LYCH as a disulphonated substance may represent an analogue of sulphonated or sulfated natural compounds like some flavonoids. We performed uptake experiments with LYCH into isolated rye vacuoles and observed saturable (Km = 0.3-0.6 mM) vacuolar transport and accumulation of the dye against the concentration gradient only when MgATP was present. GTP and, to a low extent, UTP could substitute for ATP, while the non-hydrolysable ATP analogue AMP-PNP did not drive LYCH uptake. Vanadate and probenecid, the latter substance is known to inhibit organic anion transport at the liver canalicular membrane, both strongly decreased the vacuolar uptake of LYCH, while bafilomycin A1, a specific inhibitor of the vacuolar H+-ATPase, had no effect. Together with the fact that abolishment of the delta pH via CCCP had only a weak influence on LYCH accumulation, our results indicate that this compound is taken up into rye vacuoles by a directly energized process. Uptake of LYCH was strongly inhibited by other sulfated compounds including sulfobromophthalein and the flavones apigenin 7,4'-disulfate and luteolin 7,4'-disulfate arguing for the presence of a vacuolar transporter for structurally different sulphonated or sulfated compounds. Glucuronates like the rye-specific flavone luteolin 7-O-diglucuronide also strongly decreased uptake of the dye, whereas only a weak effect was observed in the presence of glutathione and a glutathione conjugate, suggesting that LYCH uptake is not mediated via the vacuolar glutathione conjugate pump.

  12. Basic priority rating model 2.0: current applications for priority setting in health promotion practice.

    PubMed

    Neiger, Brad L; Thackeray, Rosemary; Fagen, Michael C

    2011-03-01

    Priority setting is an important component of systematic planning in health promotion and also factors into the development of a comprehensive evaluation plan. The basic priority rating (BPR) model was introduced more than 50 years ago and includes criteria that should be considered in any priority setting approach (i.e., use of predetermined criteria, standardized comparisons, and a rubric that controls bias). Although the BPR model has provided basic direction in priority setting, it does not represent the broad array of data currently available to decision makers. Elements in the model also give more weight to the impact of communicable diseases compared with chronic diseases. For these reasons, several modifications are recommended to improve the BPR model and to better assist health promotion practitioners in the priority setting process. The authors also suggest a new name, BPR 2.0, to represent this revised model.

  13. Solid Earth: The priorities

    NASA Astrophysics Data System (ADS)

    Paquet, P.

    1991-10-01

    The European Space Agency's strategy concerning the solid Earth program is reviewed. Improvement of current knowledge of the global geopotential fields, both gravity and magnetic, was stressed as the highest priority. It was agreed that the objectives and goals of the planned Aristoteles mission correspond to this priority, and the need to realize this part of the program was stated. The interdisciplinary links of the program were identified, and it was decided that this program could make substantial contributions to research of oceans, climate and global change, atmosphere, ice and land surfaces.

  14. 18 CFR 281.206 - Priority 1 reclassification.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... customer, the volume of natural gas such direct sale customer is entitled to receive for high-priority uses... its high-priority user customers under the currently effective curtailment plan of the interstate... entitlements of its direct sale customers, local distribution company customers and interstate...

  15. 18 CFR 281.206 - Priority 1 reclassification.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... customer, the volume of natural gas such direct sale customer is entitled to receive for high-priority uses... its high-priority user customers under the currently effective curtailment plan of the interstate... entitlements of its direct sale customers, local distribution company customers and interstate...

  16. 18 CFR 281.206 - Priority 1 reclassification.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... customer, the volume of natural gas such direct sale customer is entitled to receive for high-priority uses... its high-priority user customers under the currently effective curtailment plan of the interstate... entitlements of its direct sale customers, local distribution company customers and interstate...

  17. 18 CFR 281.206 - Priority 1 reclassification.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... customer, the volume of natural gas such direct sale customer is entitled to receive for high-priority uses... its high-priority user customers under the currently effective curtailment plan of the interstate... entitlements of its direct sale customers, local distribution company customers and interstate...

  18. 18 CFR 281.206 - Priority 1 reclassification.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... customer, the volume of natural gas such direct sale customer is entitled to receive for high-priority uses... its high-priority user customers under the currently effective curtailment plan of the interstate... entitlements of its direct sale customers, local distribution company customers and interstate...

  19. Safety as a Priority

    ERIC Educational Resources Information Center

    Huntress, Patricia

    2007-01-01

    Safety should be a priority in every classroom for every age group. Most art teachers know the chemicals to avoid in the student environment. It is their responsibility as art teachers to include safety information in every lesson plan and inform each student of the safety precautions they must take with each activity, without depriving them of…

  20. Faculty Internationalization Priorities

    ERIC Educational Resources Information Center

    Criswell, John R., II; Zhu, Hao

    2015-01-01

    The internationalization of higher education has been the subject of a substantial body of research. However, few studies have examined how faculty members, significant implementers of internationalization, think about internationalization priorities. This article presents the results of a questionnaire which was sent to faculty members at three…

  1. Registration Priorities: A Report.

    ERIC Educational Resources Information Center

    Walters, Judy E.

    In May 1993, the California Community Colleges' Board of Governors adopted systemwide guidelines recommending student registration priorities to help address current discrepancies between available resources and courses and the colleges' open-door mission. This report describes the guidelines and results of a study conducted to determine their…

  2. Priorities for Health Education.

    ERIC Educational Resources Information Center

    Duncan, David F.

    Twelve priority areas for health education in the 1980s are identified, based on the magnitude and seriousness of the problems addressed; the solidity of the research base; and the likelihood that health education may facilitate improvement in the area. The twelve areas are: (1) cigarette smoking; (2) aging and the aged; (3) mental health; (4)…

  3. Managing Organizational Priorities.

    ERIC Educational Resources Information Center

    Brightman, Baird K.; Moran, John W.

    2001-01-01

    Suggests that individuals can compile an action plan for professional and organizational change that aligns personal and organizational priorities by considering leadership, coaching, corporate citizenship, change management, efficiency, teamwork, customer focus, and decision making. Presents models and assessment instruments for personal…

  4. Priorities for Health Education.

    ERIC Educational Resources Information Center

    Duncan, David F.

    Twelve priority areas for health education in the 1980s are identified, based on the magnitude and seriousness of the problems addressed; the solidity of the research base; and the likelihood that health education may facilitate improvement in the area. The twelve areas are: (1) cigarette smoking; (2) aging and the aged; (3) mental health; (4)…

  5. Hazardous substances in the aquatic environment of Estonia.

    PubMed

    Roots, Ott; Roose, Antti

    2013-09-01

    The Water Framework Directive (WFD) aims to regulate the management of European surface water bodies. Directive 2008/105/EC, which establishes the environmental quality standards of priority substances and certain other pollutants, the content of which in the surface water should be monitored, has been transposed by the Estonian Ministry of Environment 9 September 2010 Regulation No. 49. Sampled hazardous substances were selected primarily based on their toxicity, as well as their lifetime in environment and ability to accumulate in living organisms (bioaccumulation). The contents of hazardous substances and their groups determined from Estonian surface waters remained below the limits of quantifications of used analysis methods in most cases. However, the content of some heavy metals, mono- and dibasic phenols in the surface water/waste water and sewage sludge/bottom sediments can still reach the delicate levels in the Estonian oil shale region in particular. Among new substances analysed in Estonia historically first time in 2010, amounts of organotin compounds in sediments and some alkylphenols, their ethoxylates and phthalates were found in various sample matrices.

  6. Development of risk perception and substance use of tobacco, alcohol and cannabis among adolescents and emerging adults: evidence of directional influences.

    PubMed

    Grevenstein, Dennis; Nagy, Ede; Kroeninger-Jungaberle, Henrik

    2015-02-01

    While several studies have investigated the relationship between risk perception and substance use, surprisingly little is known about mutual influences between both variables over time. The present study aimed to explore two different hypotheses separately for tobacco, alcohol and cannabis: influences from risk perception on behavior (motivational hypothesis) and influences from behavior on risk perception (risk reappraisal hypothesis). A prospective and longitudinal cross-lagged panel design was used with substance use and risk perception measured five times over the course of 10 years. Participants were 318 German youths aged 14-15 at the beginning of the study. Risk perception and substance use frequency were measured using self-reports. Structural equation modeling indicated significant influences of risk perception on substance use behavior for all substances, which supports the motivational hypothesis. Changes in risk perception predict changes in future substance use of tobacco, alcohol and cannabis. Specifically for cannabis, influences of substance use on risk perception can also be shown, thus, supporting the risk reappraisal hypothesis. While there is support for the rationale behind adequate risk perception as a goal of preventive interventions, the possibility of risk reappraisal should not be neglected, especially regarding illicit substances.

  7. Direct Detection of Fe(II) in Extracellular Polymeric Substances (EPS) at the Mineral-Microbe Interface in Bacterial Pyrite Leaching.

    PubMed

    Mitsunobu, Satoshi; Zhu, Ming; Takeichi, Yasuo; Ohigashi, Takuji; Suga, Hiroki; Jinno, Muneaki; Makita, Hiroko; Sakata, Masahiro; Ono, Kanta; Mase, Kazuhiko; Takahashi, Yoshio

    2016-01-01

    We herein investigated the mechanisms underlying the contact leaching process in pyrite bioleaching by Acidithiobacillus ferrooxidans using scanning transmission X-ray microscopy (STXM)-based C and Fe near edge X-ray absorption fine structure (NEXAFS) analyses. The C NEXAFS analysis directly showed that attached A. ferrooxidans produces polysaccharide-abundant extracellular polymeric substances (EPS) at the cell-pyrite interface. Furthermore, by combining the C and Fe NEXAFS results, we detected significant amounts of Fe(II), in addition to Fe(III), in the interfacial EPS at the cell-pyrite interface. A probable explanation for the Fe(II) in detected EPS is the leaching of Fe(II) from the pyrite. The detection of Fe(II) also indicates that Fe(III) resulting from pyrite oxidation may effectively function as an oxidizing agent for pyrite at the cell-pyrite interface. Thus, our results imply that a key role of Fe(III) in EPS, in addition to its previously described role in the electrostatic attachment of the cell to pyrite, is enhancing pyrite dissolution.

  8. Direct Detection of Fe(II) in Extracellular Polymeric Substances (EPS) at the Mineral-Microbe Interface in Bacterial Pyrite Leaching

    PubMed Central

    Mitsunobu, Satoshi; Zhu, Ming; Takeichi, Yasuo; Ohigashi, Takuji; Suga, Hiroki; Jinno, Muneaki; Makita, Hiroko; Sakata, Masahiro; Ono, Kanta; Mase, Kazuhiko; Takahashi, Yoshio

    2016-01-01

    We herein investigated the mechanisms underlying the contact leaching process in pyrite bioleaching by Acidithiobacillus ferrooxidans using scanning transmission X-ray microscopy (STXM)-based C and Fe near edge X-ray absorption fine structure (NEXAFS) analyses. The C NEXAFS analysis directly showed that attached A. ferrooxidans produces polysaccharide-abundant extracellular polymeric substances (EPS) at the cell-pyrite interface. Furthermore, by combining the C and Fe NEXAFS results, we detected significant amounts of Fe(II), in addition to Fe(III), in the interfacial EPS at the cell-pyrite interface. A probable explanation for the Fe(II) in detected EPS is the leaching of Fe(II) from the pyrite. The detection of Fe(II) also indicates that Fe(III) resulting from pyrite oxidation may effectively function as an oxidizing agent for pyrite at the cell-pyrite interface. Thus, our results imply that a key role of Fe(III) in EPS, in addition to its previously described role in the electrostatic attachment of the cell to pyrite, is enhancing pyrite dissolution. PMID:26947441

  9. Assigning Priorities for Fixed Priority Preemption Threshold Scheduling

    PubMed Central

    2015-01-01

    Preemption threshold scheduling (PTS) enhances real-time schedulability by controlling preemptiveness of tasks. This benefit of PTS highly depends on a proper algorithm that assigns each task feasible scheduling attributes, which are priority and preemption threshold. Due to the existence of an efficient optimal preemption threshold assignment algorithm that works with fully assigned priority orderings, we need an optimal priority assignment algorithm for PTS. This paper analyzes the inefficiency or nonoptimality of the previously proposed optimal priority assignment algorithms for PTS. We develop theorems for exhaustively but safely pruning infeasible priority orderings while assigning priorities to tasks for PTS. Based on the developed theorems, we correct the previously proposed optimal priority assignment algorithm for PTS. We also propose a performance improved optimal priority assignment algorithm for PTS proving its optimality. The empirical evaluation results clearly show the effectiveness of the proposed algorithm. PMID:26688828

  10. Federal Register Notice: Procedures for Prioritization of Chemicals for Risk Evaluation Under the Toxic Substances Control Act

    EPA Pesticide Factsheets

    EPA is issuing a final rule that establishes the process and criteria that EPA will use to identify chemical substances as either High-Priority Substances for risk evaluation,or Low-Priority Substances for which risk evaluations are not warranted.

  11. Priorities for Venus Exploration

    NASA Astrophysics Data System (ADS)

    Glaze, L. S.; Beauchamp, P. M.; Chin, G.; Crisp, D.; Grimm, R. E.; Herrick, R. R.; Johnston, S.; Limaye, S. S.; Smrekar, S. E.; Ocampo, A.; Thompson, T. W.

    2013-12-01

    Venus remains one of the most enigmatic bodies in our Solar System. Important questions remain regarding the origin and evolution of the atmosphere, the history of the surface and interior, and how the surface and atmosphere interact. In a broader context, understanding Venus has implications for understanding the evolution of terrestrial planets in our Solar System as well as for interpreting the growing set of observations of extra-solar planets. The Venus Exploration Analysis Group (VEXAG), established in 2005, is chartered by NASA's Planetary Science Division and reports its findings to the NASA Advisory Council. Open to all interested scientists, VEXAG regularly evaluates Venus exploration goals, scientific objectives, investigations and critical measurement requirements, including especially recommendations in the NRC Decadal Survey and the Solar System Exploration Strategic Roadmap. At the last general meeting in November 2012, VEXAG resolved to update the scientific priorities and strategies for Venus exploration. To achieve this goal, three major tasks were defined for 2013, (1) update the document prioritizing Goals, Objectives and Investigations for Venus Exploration, (2) develop a Roadmap for Venus exploration that is consistent with VEXAG priorities as well as Planetary Decadal Survey priorities, and (3) develop a white paper on technologies for Venus missions. Proposed versions of all three documents were presented at the VEXAG general meeting in November 2013. Here, we present the findings and final versions of all three documents for community comment and feedback. A follow-on Workshop on Venus Exploration Targets is also being planned for the early summer of 2014. The workshop will provide a forum for the Venus science community to discuss approaches for addressing high priority investigations. Participants will be encouraged to present their ideas for specific targets on Venus (interior, surface and atmosphere) as well as to present specific data

  12. Priorities in Ocean Science Study

    ERIC Educational Resources Information Center

    Awkerman, Gary L.; And Others

    1974-01-01

    Reports on a national survey conducted to determine priorities in ocean science study as identified by oceanographers. The priority determinations gave equal weight to relevance and academic importance of ocean problems. (Author/GS)

  13. National Priorities List Reform. A More Flexible Approach for Federal Facilities

    DTIC Science & Technology

    1998-03-01

    to establish criteria for listing national priorities among the known or threatened hazardous substance releases throughout the United States. CERCLA ...1 SPRING 1998BRAC Environmental Fact Sheet DR AF T National Priorities List ReformOFFICE OF THEDEPUTY UNDER SECRETARY OF DEFENSE (ENVIRONMENTAL...sites from the National Priorities List (NPL). One of the most important changes for DoD allows for the deletion of portions of NPL sites. Formerly

  14. Use of antibodies directed against blood group substances and lectins together with glycosidase digestion to study the composition and cellular distribution of glycoproteins in the large human airways

    PubMed Central

    BALS, ROBERT; WOECKEL, WERNER; WELSCH, ULRICH

    1997-01-01

    Some 30 lectins in combination with glycosidase digestion and immunohistochemistry with 5 antibodies directed against antigens of the ABO and Lewis blood group systems were used to analyse the distribution and synthesis of glycoconjugates in the epithelium of the large airways in man. Both mucous gland cells and goblet cells were labelled by 12 of 30 lectins and by the antibodies, dependent on the ABO, Lewis, and secretor status. The corresponding binding patterns of the serous gland cells differed markedly from those of goblet and mucous gland cells and in general were not dependent on the ABO, Lewis, and secretor status. After digestion with neuraminidase and fucosidase, binding of soy bean agglutinin and peanut agglutinin to goblet and mucous gland cells was increased. Binding of peanut agglutinin to serous gland cells was stronger only after the digestion with neuraminidase. Digestion with O-glycosidase after the use of neuraminidase or fucosidase resulted in a decrease of peanut agglutinin binding to goblet and mucous gland cells. The present results show that the secretory products of goblet and mucous gland cells on the one hand and those of serous cells on the other differ considerably with respect to their terminal glycosylation. The glycosyltransferases coded by genes of the ABO and Lewis blood group and secretor systems are active only in goblet and mucous gland cells, resulting in the presence of the corresponding antigens. Precursor substances of blood group antigens types 1, 2, and 3 are found only in these cell types. In serous gland cells, blood group systems do not influence the glycosylation of glycoproteins. The results of the digestion with O-glycosidase indicates the presence of O-glycosylation in mucous gland and goblet cells, but not in serous gland cells. PMID:9034883

  15. BRIEF INTERVENTIONS IN SUBSTANCE ABUSE

    PubMed Central

    Kumar, Suresh; Malhotra, Anil

    2000-01-01

    Brief interventions in substance abuse refer to a group of cost-effective and time efficient strategies that aim at reduction of substance use and/or harm related to substance use. They are grounded in the scientific principles of harm reduction stage of change, motivational interviewing and feasibility of community-level delivery. This review discusses the characteristics, elements, and techniques of brief interventions for abuse of alcohol, tobacco and other drugs. The available evidence for effectiveness of these strategies vis-a-vis no treatment or extended treatment is also reviewed, which clearly supports these interventions to be effective, especially for alcohol abuse but also for others It is argued that India presents a fertile ground for application of these strategies and that Indian research in this area should be a top priority. PMID:21407932

  16. 75 FR 59983 - National Priorities List, Final Rule-Newtown Creek

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... and Hazardous Substances Pollution Contingency Plan (``NCP'') include a list of national priorities... Hazardous Substances Pollution Contingency Plan (``NCP''), 40 CFR part 300, on July 16, 1982 (47 FR 31180... pathways: Ground water, surface water, soil exposure, and air. As a matter of Agency policy, those...

  17. 15 CFR 700.11 - Priority ratings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Priority ratings. 700.11 Section 700... DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Industrial Priorities § 700.11 Priority ratings. (a) Levels of priority. (1) There are two levels of priority established by this regulation, identified by the rating...

  18. Priority Queues for Computer Simulations

    NASA Technical Reports Server (NTRS)

    Steinman, Jeffrey S. (Inventor)

    1998-01-01

    The present invention is embodied in new priority queue data structures for event list management of computer simulations, and includes a new priority queue data structure and an improved event horizon applied to priority queue data structures. ne new priority queue data structure is a Qheap and is made out of linked lists for robust, fast, reliable, and stable event list management and uses a temporary unsorted list to store all items until one of the items is needed. Then the list is sorted, next, the highest priority item is removed, and then the rest of the list is inserted in the Qheap. Also, an event horizon is applied to binary tree and splay tree priority queue data structures to form the improved event horizon for event management.

  19. Priority nutrition messages.

    PubMed

    1991-01-01

    The Philippine Food and Nutrition Program deliver priority short, simple, clear, and action filled nutrition messages in different languages and dialects to different audiences. Its 1st priority task is to promote breast feeding. It informs mothers that breast milk is the most nutritious food for infants and that it protects them from infectious diseases. The program also encourages breast feeding as long as possible. If mothers cannot breast feed, they should talk to an infant nutrition expert to help them choose the best formula and learn about proper preparation. A 4-6 month infant needs to begin eating small amounts of semisolid nutritious foods. Moreover these foods must include body building foods, such as meat and eggs, and energy providing foods, such as corn and rice. Mothers must 1st attend to food needs of infants and preschoolers since they are more likely to suffer malnutrition than older children and adults. This is especially important when they suffer from an infection. Specifically, the very young need a variety of foods each day including the vitamin and mineral rich vegetables and fruits. In fact, families should grow their own fruits and vegetables to ensure an adequate supply. Hands must be cleaned with soap and water after defecation and before preparing foods. Mothers should add fats and oils when preparing foods because they provide concentrated energy, fatty acids, and fat soluble vitamins. Pregnant mothers must consume increased amounts of fish, beans, and other body building foods as well as regulating foods (vegetables and fruits). Mothers must also space births. They should weigh children each month to monitor nutritional levels. Moreover they must pay attention to signs indicating inadequate and insufficient food intake e.g., underweight and night blindness.

  20. Priorities for Endometriosis Research

    PubMed Central

    Rogers, Peter A. W.; D’Hooghe, Thomas M.; Fazleabas, Asgerally; Gargett, Caroline E.; Giudice, Linda C.; Montgomery, Grant W.; Rombauts, Luk; Salamonsen, Lois A.; Zondervan, Krina T.

    2009-01-01

    Endometriosis is an estrogen-dependent disorder where endometrial tissue forms lesions outside the uterus. Endometriosis affects an estimated 10% of women in the reproductive-age group, rising to 30% to 50% in patients with infertility and/or pain, with significant impact on their physical, mental, and social well-being. There is no known cure, and most current medical treatments are not suitable long term due to their side-effect profiles. Endometriosis has an estimated annual cost in the United States of $18.8 to $22 billion (2002 figures). Although endometriosis was first described more than 100 years ago, current knowledge of its pathogenesis, spontaneous evolution, and the pathophysiology of the related infertility and pelvic pain, remain unclear. A consensus workshop was convened following the 10th World Congress on Endometriosis to establish recommendations for priorities in endometriosis research. One major issue identified as impacting on the capacity to undertake endometriosis research is the need for multidisciplinary expertise. A total of 25 recommendations for research have been developed, grouped under 5 subheadings: (1) diagnosis, (2) classification and prognosis, (3) treatment and outcome, (4) epidemiology, and (5) pathophysiology. Endometriosis research is underfunded relative to other diseases with high health care burdens. This may be due to the practical difficulties of developing competitive research proposals on a complex and poorly understood disease, which affects only women. By producing this consensus international research priorities statement it is the hope of the workshop participants that researchers will be encouraged to develop new interdisciplinary research proposals that will attract increased funding support for work on endometriosis. PMID:19196878

  1. Rapid screening of 35 new psychoactive substances by ion mobility spectrometry (IMS) and direct analysis in real time (DART) coupled to quadrupole time-of-flight mass spectrometry (QTOF-MS).

    PubMed

    Gwak, Seongshin; Almirall, Jose R

    2015-10-01

    The recent propagation of new psychoactive substances (NPS) has led to the development of new techniques for the rapid characterization of controlled substances in this category. A commercial bench-top ion mobility spectrometer (IMS) with a (63) Ni ionization source and a direct analysis in real time (DART) coupled to quadrupole time-of-flight (QTOF) were used for the rapid characterization of 35 NPS. The advantages of these techniques are fast response, ease of operation, and minimal sample preparation. The characteristic reduced mobilities of each substance are reported as are the mass spectra of the 35 compounds. The acquired product ion scan mass spectra were also compared to a library database constructed by QTOF with a electrospray ionization (ESI) source and showed a consistent relative abundance for each peak over time. A total of four seized drug samples provided by the local forensic laboratory were analyzed in order to demonstrate the utility of this approach. The results of this study suggest that both IMS and DART-QTOF are promising alternatives for the rapid screening and characterization of these new psychoactive substances.

  2. Phylogenetically-informed priorities for amphibian conservation.

    PubMed

    Isaac, Nick J B; Redding, David W; Meredith, Helen M; Safi, Kamran

    2012-01-01

    The amphibian decline and extinction crisis demands urgent action to prevent further large numbers of species extinctions. Lists of priority species for conservation, based on a combination of species' threat status and unique contribution to phylogenetic diversity, are one tool for the direction and catalyzation of conservation action. We describe the construction of a near-complete species-level phylogeny of 5713 amphibian species, which we use to create a list of evolutionarily distinct and globally endangered species (EDGE list) for the entire class Amphibia. We present sensitivity analyses to test the robustness of our priority list to uncertainty in species' phylogenetic position and threat status. We find that both sources of uncertainty have only minor impacts on our 'top 100' list of priority species, indicating the robustness of the approach. By contrast, our analyses suggest that a large number of Data Deficient species are likely to be high priorities for conservation action from the perspective of their contribution to the evolutionary history.

  3. Priorities Statements of Community Colleges.

    ERIC Educational Resources Information Center

    Illinois Community Coll. Board, Springfield.

    In response to recommendations in the Illinois Board of Higher Education's Priorities, Quality, and Productivity report of November 1994, the 52 community colleges in the state prepared priority statements detailing specific college objectives for the current fiscal year (FY). This report provides the second update of the colleges' statements,…

  4. Surface Transportation Security Priority Assessment

    DTIC Science & Technology

    2010-03-01

    Protection Plan (NIPP) framework priorities with the Sector- Specific Agencies (SSA); surface transportation owners/operators; and State, local, tribal...and recommendations. Issue Identification To identify national interagency priorities and guide Federal efforts to secure the surface...the Nation’s critical infrastructure and key resources (CIKR). These activities encompass national and sector planning and policy, program

  5. Research priorities for nursing professional development: a modified e-Delphi study.

    PubMed

    Harper, Mary G; Asselin, Marilyn E; Kurtz, Abby C; MacArthur, Susan K; Perron, Sarah

    2012-01-01

    In 2010, the National Nursing Staff Development Organization Research Committee identified the need to delineate research priorities for nursing professional development (NPD). A Delphi study with 13 experts in NPD resulted in the identification of 24 priorities for the next 5 years. These priorities provide the future direction for NPD research and funding.

  6. Final priority. Rehabilitation Training: Job-Driven Vocational Rehabilitation Technical Assistance Center. Final priority.

    PubMed

    2014-08-19

    The Assistant Secretary for Special Education and Rehabilitative Services announces a priority under the Rehabilitation Training program to establish a Job-Driven Vocational Rehabilitation Technical Assistance Center (JDVRTAC). The Assistant Secretary may use this priority for competitions in fiscal year (FY) 2014 and later years. We take this action to focus on training in an area of national need. Specifically, this priority responds to the Presidential Memorandum to Federal agencies directing them to take action to address job-driven training for the Nation's workers. The JDVRTAC will provide technical assistance (TA) to State vocational rehabilitation (VR) agencies to help them develop for individuals with disabilities training and employment opportunities that meet the needs of today's employers.

  7. Highest priority in Pakistan.

    PubMed

    Adil, E

    1968-01-01

    Responding to the challenge posed by its population problem, Pakistan's national leadership gave the highest priority to family planning in its socioeconomic development plan. In Pakistan, as elsewhere in the world, the first family planning effort originated in the private sector. The Family Planning Association of Pakistan made a tentative beginning in popularizing family planning in the country. Some clinics were opened and some publicity and education were undertaken to emphasize the need for family limitation. It was recognized soon that the government needed to assume the primarily responsibility if family planning efforts were to be successful. For the 1st plan period, 1955-60, about $10 million was allocated by the central government in the social welfare sector for voluntary family planning. The level of support continued on the same basis during the 2nd plan, 1960-65, but has been raised 4-fold in the 1965-70 scheme of family planning. Pakistan's Family Planning Association continues to play vital collaborative roles in designing and pretesting of prototype publicity material, involvement of voluntary social workers, and functional research in the clinical and public relations fields. The real breakthrough in the program came with the 3rd 5-year plan, 1965-70. High priority assigned to family planning is reflected by the total initial budget of Rs.284 million (about $60,000,000) for the 5-year period. Current policy is postulated on 6 basic assumptions: family planning efforts need to be public relations-oriented; operations should be conducted through autonomous bodies with decentralized authority at all tiers down to the grassroots level, for expeditious decision making; monetary incentives play an important role; interpersonal motivation in terms of life experience of the clientele through various contacts, coupled with mass media for publicity, can produce a sociological breakthrough; supplies and services in all related disciplines should be

  8. 18 CFR 281.207 - Priority 2 classification.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ....207 Priority 2 classification. (a) Direct sale customer. (1) Subject to paragraph (a)(2) of this section, and § 281.211 a direct sale customer may request each of its direct interstate pipeline suppliers... classification. 281.207 Section 281.207 Conservation of Power and Water Resources FEDERAL ENERGY...

  9. 18 CFR 281.207 - Priority 2 classification.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....207 Priority 2 classification. (a) Direct sale customer. (1) Subject to paragraph (a)(2) of this section, and § 281.211 a direct sale customer may request each of its direct interstate pipeline suppliers... classification. 281.207 Section 281.207 Conservation of Power and Water Resources FEDERAL ENERGY...

  10. 18 CFR 281.207 - Priority 2 classification.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....207 Priority 2 classification. (a) Direct sale customer. (1) Subject to paragraph (a)(2) of this section, and § 281.211 a direct sale customer may request each of its direct interstate pipeline suppliers... classification. 281.207 Section 281.207 Conservation of Power and Water Resources FEDERAL ENERGY...

  11. Toxic Substances Control Act

    SciTech Connect

    Not Available

    1992-05-15

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  12. Take Action on 5 Policies America Must Adopt To Reduce and Prevent Substance Abuse.

    ERIC Educational Resources Information Center

    Join Together, Boston, MA.

    The Join Together National Policy Panel presents five policies that can help communities reduce and prevent substance abuse. They are: (1) compel substance abuse treatment for criminal offenders; (2) ensure that every person who has an addiction gets treatment; (3) make substance abuse prevention an urgent priority in every community; (4) increase…

  13. Proximal Priority Laser Therapy: PPLT

    NASA Astrophysics Data System (ADS)

    Ohshiro, Toshio

    2004-09-01

    The author has, in the past, classified treatment methods for pain geometrically as point, line, two-dimensional, three-dimensional treatment and has used these over the years. However as a practitioner of western medicine, the author originally treated pain only directed at the painful site, and encountered cases where local treatment did not suffice. The author proved with SPECT and the Rand Phantom that treating the neck which is the midpoint of the brain, the center of the nervous system and the heart, the center of circulation, increased cerebral blood flow and also that laser emitted to neck will reach the spinal chord no matter from where on the neck the laser is emitted. From such research and 25 years of clinical experience, the author has created an anatomy based, systemic treatment method called the Proximal Priority Laser Therapy (PPLT) where not only the cerebral cortex, spinal chord and peripheral nerves are treated but also the tracts of blood vessels and lymph ducts are treated as well. Treatment method and cases are presented herein.

  14. 38 CFR 39.7 - Priority list.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... improvement projects (such as construction of additional or replacement facilities) when such improvements are required to continue interment operations. (2) Priority Group 2—Projects for the establishment of new... highest priority and Priority Group 4 the lowest priority, are: (1) Priority Group 1—Projects needed to...

  15. Concurrence control for transactions with priorities

    NASA Technical Reports Server (NTRS)

    Marzullo, Keith

    1989-01-01

    Priority inversion occurs when a process is delayed by the actions of another process with less priority. With atomic transactions, the concurrency control mechanism can cause delays, and without taking priorities into account can be a source of priority inversion. Three traditional concurrency control algorithms are extended so that they are free from unbounded priority inversion.

  16. Concurrency control for transactions with priorities

    NASA Technical Reports Server (NTRS)

    Marzullo, Keith

    1989-01-01

    Priority inversion occurs when a process is delayed by the actions of another process with less priority. With atomic transations, the concurrency control mechanism can cause delays, and without taking priorities into account can be a source of priority inversion. In this paper, three traditional concurrency control algorithms are extended so that they are free from unbounded priority inversion.

  17. Nursing research priorities for Ireland.

    PubMed

    Drennan, Jonathan; Meehan, Therese; Kemple, Mary; Johnson, Maree; Treacy, Margaret; Butler, Michelle

    2007-01-01

    The purpose of the study was to identify and rate clinical, managerial, and educational nursing research priorities in Ireland. The study design was a three-round, decision Delphi survey to identify and rate the importance of clinical, managerial, and educational research issues. A discussion group workshop was also undertaken to identify timeframes within which research on the issues identified should be conducted. A total of 1,695 nurses from all divisions of the nursing register in Ireland were initially surveyed. Response rates varied over the three rounds of the Delphi survey. A total of 122 nurses attended the discussion group workshop. This is the largest known survey of nurses to identify research priorities reported in the literature. Twenty-four nursing research priorities were identified. The five highest priorities were three clinical issues: outcomes of care delivery, staffing issues in practice, communication in clinical practice; and two managerial issues: recruitment and retention of nurses, and nursing input into health policy and decision-making. These research priorities identified for nursing in Ireland indicate, to an extent, the nursing research priorities identified in other European countries and in North America. The research priorities identified in this survey indicate that outcomes of care and the need to make nursing visible are attaining a higher priority than seen in previous studies. Also evident is that nursing shortages and increasing skill-mix in the clinical area have indicated a need for research into nurse recruitment, staff turnover, and staffing levels and how these issues affect patient outcomes. The priorities suggest research programmes that target the health service concerns identified in the national health agenda, such as the need to identify protocols and procedures that improve patient and client care outcomes and to examine and test solutions to workforce problems.

  18. NASA technology development priorities outlined

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2012-02-01

    NASA's technology development efforts should focus on 16 high-priority technologies and their associated top technical challenges, according to a 1 February report by a committee of the U.S. National Research Council (NRC). The report grouped technology priorities within three objectives: extend and sustain human activities beyond low-Earth orbit; explore the evolution of the solar system and the potential for life elsewhere; and expand our understanding of Earth and the universe in which we live. In pulling together its priority list, the committee boiled down priority technologies from a much longer list to “as short a list as is reasonable in the face of anticipated constrained budgets.” In addition, the committee also “assumes NASA will pursue enabling technology related to all three objectives in a balanced approach, and the committee does not advocate support for one objective over another.”

  19. Superfund: National Priorities List (NPL)

    EPA Pesticide Factsheets

    Sites are listed on the National Priorities List (NPL) upon completion of Hazard Ranking System (HRS) screening, public solicitation of comments about the proposed site, and after all public comments have been addressed.

  20. Defining Priorities for Future Research: Results of the UK Kidney Transplant Priority Setting Partnership.

    PubMed

    Knight, Simon R; Metcalfe, Leanne; O'Donoghue, Katriona; Ball, Simon T; Beale, Angela; Beale, William; Hilton, Rachel; Hodkinson, Keith; Lipkin, Graham W; Loud, Fiona; Marson, Lorna P; Morris, Peter J

    2016-01-01

    transplantation, living donation, organ preservation, post-transplant care and management of the failing transplant. This list of priorities will provide an invaluable resource for researchers and funders to direct future activity.

  1. Priority setting partnership to identify the top 10 research priorities for the management of Parkinson's disease.

    PubMed

    Deane, Katherine H O; Flaherty, Helen; Daley, David J; Pascoe, Roland; Penhale, Bridget; Clarke, Carl E; Sackley, Catherine; Storey, Stacey

    2014-12-14

    This priority setting partnership was commissioned by Parkinson's UK to encourage people with direct and personal experience of the condition to work together to identify and prioritise the top 10 evidential uncertainties that impact on everyday clinical practice for the management of Parkinson's disease (PD). The UK. Anyone with experience of PD including: people with Parkinson's (PwP), carers, family and friends, healthcare and social care professionals. Non-clinical researchers and employees of pharmaceutical or medical devices companies were excluded. 1000 participants (60% PwP) provided ideas on research uncertainties, 475 (72% PwP) initially prioritised them and 27 (37% PwP) stakeholders agreed a final top 10. Using a modified nominal group technique, participants were surveyed to identify what issues for the management of PD needed research. Unique research questions unanswered by current evidence were identified and participants were asked to identify their top 10 research priorities from this list. The top 26 uncertainties were presented to a consensus meeting with key stakeholders to agree the top 10 research priorities. 1000 participants provided 4100 responses, which contained 94 unique unanswered research questions that were initially prioritised by 475 participants. A consensus meeting with 27 stakeholders agreed the top 10 research priorities. The overarching research aspiration was an effective cure for PD. The top 10 research priorities for PD management included the need to address motor symptoms (balance and falls, and fine motor control), non-motor symptoms (sleep and urinary dysfunction), mental health issues (stress and anxiety, dementia and mild cognitive impairments), side effects of medications (dyskinesia) and the need to develop interventions specific to the phenotypes of PD and better monitoring methods. These research priorities identify crucial gaps in the existing evidence to address everyday practicalities in the management of the

  2. Priority setting partnership to identify the top 10 research priorities for the management of Parkinson's disease

    PubMed Central

    Deane, Katherine H O; Flaherty, Helen; Daley, David J; Pascoe, Roland; Penhale, Bridget; Clarke, Carl E; Sackley, Catherine; Storey, Stacey

    2014-01-01

    Objectives This priority setting partnership was commissioned by Parkinson's UK to encourage people with direct and personal experience of the condition to work together to identify and prioritise the top 10 evidential uncertainties that impact on everyday clinical practice for the management of Parkinson's disease (PD). Setting The UK. Participants Anyone with experience of PD including: people with Parkinson's (PwP), carers, family and friends, healthcare and social care professionals. Non-clinical researchers and employees of pharmaceutical or medical devices companies were excluded. 1000 participants (60% PwP) provided ideas on research uncertainties, 475 (72% PwP) initially prioritised them and 27 (37% PwP) stakeholders agreed a final top 10. Methods Using a modified nominal group technique, participants were surveyed to identify what issues for the management of PD needed research. Unique research questions unanswered by current evidence were identified and participants were asked to identify their top 10 research priorities from this list. The top 26 uncertainties were presented to a consensus meeting with key stakeholders to agree the top 10 research priorities. Results 1000 participants provided 4100 responses, which contained 94 unique unanswered research questions that were initially prioritised by 475 participants. A consensus meeting with 27 stakeholders agreed the top 10 research priorities. The overarching research aspiration was an effective cure for PD. The top 10 research priorities for PD management included the need to address motor symptoms (balance and falls, and fine motor control), non-motor symptoms (sleep and urinary dysfunction), mental health issues (stress and anxiety, dementia and mild cognitive impairments), side effects of medications (dyskinesia) and the need to develop interventions specific to the phenotypes of PD and better monitoring methods. Conclusions These research priorities identify crucial gaps in the existing evidence to

  3. Reconnaissance of toxic substances in the Jordan River, Salt Lake County, Utah

    USGS Publications Warehouse

    Thompson, Kendall R.

    1984-01-01

    A reconnaissance of toxic substances in the Jordan River, Salt Lake County, Utah, was made during July, 1980 to October, 1982 as part of a larger study of the river that included studies of sanitary quality, dissolved oxygen, and turbidity. Samples for toxic substances were collected at five sites on the Jordan River, at three major tributaries, and at six storm drains. The toxic substance that most frequently exceeded State standards was total mercury. About 78 percent of the 138 samples for total mercury exceeded the State standard of 0.05 microgram per liter. Other toxic substances that exceeded State standards were: Ammonia-18 percent of the samples analyzed, cadmium--9 percent, copper-9 percent, zinc--6 percent, and lead--2 percent. One sample for cyanide and one for iron also exceeded State standards. The diversity of toxic substances with concentrations large enough to cause them to be problems increased from the upstream sampling site at the Jordan Narrows to the next two downstream sites at 9000 South and 5800 South Streets. Concentrations of trace elements in stream-bottom materials also increased in a downstream direction. Substantial increases first were observed at 5800 South Street, and they were sustained throughout the downstream study area. Iron is transported in the greatest quantity of all the trace elements studied, with a mean load of 110 pounds per day. Notable loads of barium, boron, lead , and zinc also are transported by the river. DDD, DDE, DDT, dieldrin, heptachlor, methoxychlor, PCB, and 2,4-D were detected in bottom materials; and DDE, Silvex, and 2,4-D were detected in water samples. Of 112 organic compounds in the Environmental Protection Agency 's priority pollutant list, only chloroform was detected in the storm drains that empty into the Joran River. Several metals and phenol also were detected in the samples for priority pollutants. (USGS)

  4. Partner violence and substance abuse are intertwined: women's perceptions of violence-substance connections.

    PubMed

    Macy, Rebecca J; Renz, Connie; Pelino, Emily

    2013-07-01

    Research shows that co-occurring partner violence and substance abuse are problems for many women. However, less is known about women's varied experiences with partner violence and substance abuse. This exploratory, qualitative study investigates these two issues among a sample of 15 women in substance abuse treatment who experienced partner violence. Overall, findings show participants' experience of violence-substance connections varied in important ways; complicating factors exacerbate both problems; and domestic violence services and substance abuse treatments should account for these variations and complications. We discuss directions for providers, researchers, and policymakers concerned with partner violence or substance abuse.

  5. Other- and Self-Directed Forms of Violence and Their Relationship With Number of Substance Use Disorder Criteria Among Youth Ages 12–17: Results From the National Survey on Drug Use and Health

    PubMed Central

    Harford, Thomas C.; Chen, Chiung M.; Grant, Bridget F.

    2016-01-01

    Objective: The purpose of this study was to examine the associations between the number of substance use disorder (SUD) criteria as listed in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and other- and self-directed forms of violence among youth ages 12–17 in the general population. Method: Data were obtained from the National Survey on Drug Use and Health pooled across survey years 2008–2013, with a combined sample of 108,560 respondents ages 12–17. Violence categories defined by suicide attempt (self-directed) and attacking someone with the intent for serious injury (other-directed) were categorized as follows: none, self-directed only, other-directed only, and combined self-/other-directed. Multinomial logistic regression estimated odds ratios of the increased number of criteria for alcohol, marijuana, and other illicit drug use, and nicotine dependence for each violence category, by controlling for sociodemographics and criminal justice involvement. Results: The multivariable model indicates that increased number of SUD criteria confers significantly higher odds for each violence category versus no violence. For combined violence versus self-directed violence, male gender, non-Hispanic Black and mixed race (with non-Hispanic White as referent), nicotine dependence, increased number of alcohol use disorder criteria, and other drug use disorder criteria have significantly higher odds, whereas Native Hawaiian/Pacific Islander and age have significantly lower odds. For combined violence versus other-directed violence, non-Hispanic mixed race and the increased number of other drug use disorder criteria have significantly higher odds, whereas male gender, non-Hispanic Black and Native Hawaiian/Pacific Islander, and Hispanic have significantly lower odds. Conclusions: The identification of the combined self-/other-directed violence in the general population provides additional support for clinical studies that established

  6. Other- and Self-Directed Forms of Violence and Their Relationship With Number of Substance Use Disorder Criteria Among Youth Ages 12-17: Results From the National Survey on Drug Use and Health.

    PubMed

    Harford, Thomas C; Chen, Chiung M; Grant, Bridget F

    2016-03-01

    The purpose of this study was to examine the associations between the number of substance use disorder (SUD) criteria as listed in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and other- and self-directed forms of violence among youth ages 12-17 in the general population. Data were obtained from the National Survey on Drug Use and Health pooled across survey years 2008-2013, with a combined sample of 108,560 respondents ages 12-17. Violence categories defined by suicide attempt (self-directed) and attacking someone with the intent for serious injury (other-directed) were categorized as follows: none, self-directed only, other-directed only, and combined self-/other-directed. Multinomial logistic regression estimated odds ratios of the increased number of criteria for alcohol, marijuana, and other illicit drug use, and nicotine dependence for each violence category, by controlling for sociodemographics and criminal justice involvement. The multivariable model indicates that increased number of SUD criteria confers significantly higher odds for each violence category versus no violence. For combined violence versus self-directed violence, male gender, non-Hispanic Black and mixed race (with non-Hispanic White as referent), nicotine dependence, increased number of alcohol use disorder criteria, and other drug use disorder criteria have significantly higher odds, whereas Native Hawaiian/Pacific Islander and age have significantly lower odds. For combined violence versus other-directed violence, non-Hispanic mixed race and the increased number of other drug use disorder criteria have significantly higher odds, whereas male gender, non-Hispanic Black and Native Hawaiian/Pacific Islander, and Hispanic have significantly lower odds. The identification of the combined self-/other-directed violence in the general population provides additional support for clinical studies that established associations between self- and other-directed violent

  7. Global health prioritiespriorities of the wealthy?

    PubMed Central

    Ollila, Eeva

    2005-01-01

    Health has gained importance on the global agenda. It has become recognized in forums where it was once not addressed. In this article three issues are considered: global health policy actors, global health priorities and the means of addressing the identified health priorities. I argue that the arenas for global health policy-making have shifted from the public spheres towards arenas that include the transnational for-profit sector. Global health policy has become increasingly fragmented and verticalized. Infectious diseases have gained ground as global health priorities, while non-communicable diseases and the broader issues of health systems development have been neglected. Approaches to tackling the health problems are increasingly influenced by trade and industrial interests with the emphasis on technological solutions. PMID:15847685

  8. The Hidradenitis Suppurativa Priority Setting Partnership.

    PubMed

    Ingram, J R; Abbott, R; Ghazavi, M; Alexandroff, A B; McPhee, M; Burton, T; Clarke, T

    2014-12-01

    Hidradenitis suppurativa (HS) has been neglected by medical researchers and society in general, despite being a relatively common, painful, chronic skin disease. To generate a top 10 list of HS research priorities, from the perspectives of patients with HS, carers and clinicians, to take to funding bodies. A priority setting partnership was established between patients with HS, carers and clinicians, following the James Lind Alliance process. Survey 1 requested submission of HS uncertainties, which were grouped into 'indicative uncertainties' for prioritization in survey 2. The 30 highest-ranked indicative uncertainties were reduced to a 'top 10' list using nominal group technique at a prioritization workshop attended by all relevant HS stakeholders. In total 1495 potential uncertainties were submitted in survey 1, including 57% from patients with HS and carers, and grouped into 55 indicative uncertainties. Ranking in survey 2 was completed by 371 participants, 50% of whom were patients and carers. The final workshop was attended by 22 HS stakeholders and four facilitators and produced a top 10 list, the three highest priorities in descending order being (i) What is the most effective and safe group of oral treatments in treating HS? (ii) What is the best management of an acute flare? (iii)What is the impact of HS and its treatment on people with HS? The top 10 HS research priorities have been directly disseminated to funders to raise awareness of HS. The next step is to generate research questions that will provide the evidence needed to improve care for patients with HS. © 2014 British Association of Dermatologists.

  9. Global Climate Change Adaptation Priorities for Biodiversity and Food Security

    PubMed Central

    Hannah, Lee; Ikegami, Makihiko; Hole, David G.; Seo, Changwan; Butchart, Stuart H. M.; Peterson, A. Townsend; Roehrdanz, Patrick R.

    2013-01-01

    International policy is placing increasing emphasis on adaptation to climate change, including the allocation of new funds to assist adaptation efforts. Climate change adaptation funding may be most effective where it meets integrated goals, but global geographic priorities based on multiple development and ecological criteria are not well characterized. Here we show that human and natural adaptation needs related to maintaining agricultural productivity and ecosystem integrity intersect in ten major areas globally, providing a coherent set of international priorities for adaptation funding. An additional seven regional areas are identified as worthy of additional study. The priority areas are locations where changes in crop suitability affecting impoverished farmers intersect with changes in ranges of restricted-range species. Agreement among multiple climate models and emissions scenarios suggests that these priorities are robust. Adaptation funding directed to these areas could simultaneously address multiple international policy goals, including poverty reduction, protecting agricultural production and safeguarding ecosystem services. PMID:23991125

  10. Global climate change adaptation priorities for biodiversity and food security.

    PubMed

    Hannah, Lee; Ikegami, Makihiko; Hole, David G; Seo, Changwan; Butchart, Stuart H M; Peterson, A Townsend; Roehrdanz, Patrick R

    2013-01-01

    International policy is placing increasing emphasis on adaptation to climate change, including the allocation of new funds to assist adaptation efforts. Climate change adaptation funding may be most effective where it meets integrated goals, but global geographic priorities based on multiple development and ecological criteria are not well characterized. Here we show that human and natural adaptation needs related to maintaining agricultural productivity and ecosystem integrity intersect in ten major areas globally, providing a coherent set of international priorities for adaptation funding. An additional seven regional areas are identified as worthy of additional study. The priority areas are locations where changes in crop suitability affecting impoverished farmers intersect with changes in ranges of restricted-range species. Agreement among multiple climate models and emissions scenarios suggests that these priorities are robust. Adaptation funding directed to these areas could simultaneously address multiple international policy goals, including poverty reduction, protecting agricultural production and safeguarding ecosystem services.

  11. Contamination of packaged food by substances migrating from a direct-contact plastic layer: Assessment using a generic quantitative household scale methodology.

    PubMed

    Vitrac, Olivier; Challe, Blandine; Leblanc, Jean-Charles; Feigenbaum, Alexandre

    2007-01-01

    The contamination risk in 12 packaged foods by substances released from the plastic contact layer has been evaluated using a novel modeling technique, which predicts the migration that accounts for (i) possible variations in the time of contact between foodstuffs and packaging and (ii) uncertainty in physico-chemical parameters used to predict migration. Contamination data, which are subject to variability and uncertainty, are derived through a stochastic resolution of transport equations, which control the migration into food. Distributions of contact times between packaging materials and foodstuffs were reconstructed from the volumes and frequencies of purchases of a given panel of 6422 households, making assumptions about household storage behaviour. The risk of contamination of the packaged foods was estimated for styrene (a monomer found in polystyrene yogurt pots) and 2,6-di-tert-butyl-4-hydroxytoluene (a representative of the widely used phenolic antioxidants). The results are analysed and discussed regarding sensitivity of the model to the set parameters and chosen assumptions.

  12. [Environment and health: priorities for preventive medicine].

    PubMed

    Rakhmanin, Yu A; Mikhaylova, R I

    2014-01-01

    Contemporary environmental factors influencing the formation of the environment and public health have been analyzed The increasing chemical pollution of the environment (air water, soil, living environment), and the intensification of the impact of physical factors in the first place, "electromagnetic smog" associated with the widespread use of appliances and computer equipment, cellular threaten public health have been shown. In this connection, there were determined priorities and main directions of research in the platform "Preventive Environment", approved by Ministry of Health of Russia, which is based on the concept of the factor prevention of noninfectious diseases.

  13. Substance Abuse/Use

    MedlinePlus

    ... Substance Abuse/Use Subscribe Translate Text Size Print Substance Abuse/Use How Are Alcohol and Drug Use Related ... or transmitting HIV is to stop using drugs . Substance abuse treatment programs can help you do this. Many ...

  14. Matrix effect and cross-reactivity of select amphetamine-type substances, designer analogues, and putrefactive amines using the Bio-Quant direct ELISA presumptive assays for amphetamine and methamphetamine.

    PubMed

    Apollonio, Luigino G; Whittall, Ian R; Pianca, Dennis J; Kyd, Jennelle M; Maher, William A

    2007-05-01

    The aim of this study was to evaluate the Bio-Quant Direct ELISA assays for amphetamine and methamphetamine in the routine presumptive screening of biological fluids. Standard concentration curves of the target analytes were assayed to assess sensitivity, and known concentrations of common amphetamine-type substances (ephedrine, pseudoephedrine, phentermine), designer analogues (MDA, MDMA, MDEA, MBDB, PMA, 4-MTA, 2CB), and putrefactive amines (phenylethylamine, putrescine, tryptamine, tyramine) were analyzed to determine cross-reactivity. Results of the standard curve studies show the capacity of both Direct ELISA kits to confidently detect down to 3 ng/mL interday (PBS matrix; CVs 6.3-15.5%). Cross-reactivity relative to that of 50 ng/mL preparations of the target compounds demonstrated that the Direct ELISA kit for amphetamine also detected MDA (282%), PMA (265%), 4-MTA (280%), and phentermine (61%), and the Direct ELISA for methamphetamine also assayed positive for MDMA (73%), MDEA (18%), pseudoephedrine (19%), MBDB (8%), and ephedrine (9%). Matrix studies demonstrated that both ELISA kits could be applied to screening of blood, urine, and saliva to a concentration of 6 ng/mL or lower. In conclusion, the Bio-Quant Direct ELISA kits for amphetamine and methamphetamine are fast and accurate and have demonstrated themselves to be useful tools in routine toxicological testing.

  15. Toward Priorities for Aging Research

    PubMed Central

    2014-01-01

    Abstract The global population is aging, and although age remains the primary risk factor for all major causes of death, no priorities for aging research exist. After reviewing the literature on mortality modeling, we found that different chronic processes underlie mortality before and after reproductive age. To identify priorities in aging research, we propose a simple ranking method that uses the percentage of deaths attributable to each disease for the over 60 population on the basis that, rather than being the result of individual risk factors, these deaths are largely due to underlying senescent processes. Our ranking suggests that vascular aging, led by ischemic heart disease and stroke, is the most important focus for aging research. The availability of funding, however, is not currently aligned with health priorities, and we believe that rectifying this disconnect may improve societal health outcomes. PMID:24094115

  16. Toward priorities for aging research.

    PubMed

    Needham, Scott L

    2014-04-01

    The global population is aging, and although age remains the primary risk factor for all major causes of death, no priorities for aging research exist. After reviewing the literature on mortality modeling, we found that different chronic processes underlie mortality before and after reproductive age. To identify priorities in aging research, we propose a simple ranking method that uses the percentage of deaths attributable to each disease for the over 60 population on the basis that, rather than being the result of individual risk factors, these deaths are largely due to underlying senescent processes. Our ranking suggests that vascular aging, led by ischemic heart disease and stroke, is the most important focus for aging research. The availability of funding, however, is not currently aligned with health priorities, and we believe that rectifying this disconnect may improve societal health outcomes.

  17. Dreissenid mussel research priorities workshop

    USGS Publications Warehouse

    Sytsma, Mark; Phillips, Stephen; Counihan, Timothy D.

    2015-01-01

    Currently, dreissenid mussels have yet to be detected in the northwestern part of the United States and western Canada. Infestation of one of the jurisdictions within the mussel-free Pacific Northwest would likely have significant economic, soci­etal and environmental implications for the entire region. Understanding the biology and environmental tolerances of dreissenid mussels, and effectiveness of various man­agement strategies, is key to prevention.On November 4-5, 2015, the Aquatic Bioinvasion Research and Policy Institute and the Center for Lakes and Reservoirs at Portland State University, the US Geological Survey, and the Pacific States Marine Fisheries Commission, convened a Dreissenid Mussel Research Priorities Workshop funded by the Great Northern Landscape Conservation Cooperative. The purpose of the workshop was to review dreissenid research priorities in the 2010 Quagga-Zebra Mussel Action Plan for Western U.S. Waters, reassess those priorities, incorporate new information and emerging trends, and develop priorities to strategically focus research efforts on zebra and quagga mussels in the Pacific Northwest and ensure that future research is focused on the highest priorities. It is important to note that there is some repetition among dreissenid research priority categories (e.g., prevention, detection, control, monitoring, and biology).Workshop participants with research experience in dreissenid mussel biology and management were identified by a literature review. State and federal agency managers were also invited to the workshop to ensure relevancy and practicality of the work­shop outcomes. A total of 28 experts (see sidebar) in mussel biology, ecology, and management attended the workshop.

  18. Site deletion from the National Priorities List. CERCLA Information Brief

    SciTech Connect

    Whitehead, B.

    1993-11-01

    Section 105 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980, as amended by the Superfund Amendments and Reauthorization Act (SARA) of 1986, requires the US Environmental Protection Agency (EPA) to maintain a National Priorities List (NPL) of releases or potential releases of hazardous substances, pollutants, or contaminants that warrant further investigation to determine if they pose risks to human health and the environment. Typically a site is placed on the NPL based on its score derived by applying the Hazard Ranking System (HRS), a screening mechanism EPA uses to evaluate the relative threat to human health and the environment posed by the release, or potential release, of hazardous substances into the environment. Sites scoring 28.50 or greater are eligible for the NPL. Additionally, each state may designate one top-priority site, regardless of the HRS score. Infrequently, EPA may utilize provisions established under 40 CFR 300.425(c)(3) to place a site on the NPL. A site may be deleted from the NPL if it is determined that no further response is required to protect human health and the environment. To date, EPA has deleted 51 sites from the NPL. The criteria and procedures for deleting a site from the NPL, as established by the National Oil and Hazardous Substances Pollution Contingency Plan, otherwise known as the National Contingency Plan (NCP), and other relevant policies are the subject of this Information Brief.

  19. Substance abuse and oral health: an overview.

    PubMed

    van Zyl, A W

    2014-02-01

    Substance abuse is a worldwide phenomenon. It is on the increase in most countries and claims the lives of millions every year. Substance abuse may involve licit and illicit drugs, with licit substances claiming more lives than illicit drugs. Illicit substance abuse is on the increase, especially with new drugs emerging on the world market every year. These new drugs appear faster than scientific studies can keep pace in determining their possible detrimental influences on health. Many abused drugs do have oral health complications. For this reason, it is important for dentists to have a thorough knowledge of the oral environment to be able to detect any abnormalities, regardless of what the underlying cause may be. Due to the nature of illicit substance abuse, reliable information and science is hard to come by. This overview will focus on the direct consequences for oral health, whilst acknowledging that substance abuse may also have direct and indirect influences on general health.

  20. Cairo conference affirms CEDPA priorities.

    PubMed

    1995-01-01

    The International Conference on Population and Development (ICPD) that was held in Cairo during September adopted a 20-year Programme of Action endorsing the empowerment of women as the foundation of sustainable development. 178 countries and more than a 1000 nongovernmental organizations (NGOs), including the Centre for Development and Population Activities (CEDPA), from 100 countries attended the conference and the parallel NGO forum. The final document sets out specific steps for achievement of universal access to a full range of voluntary, quality family planning and reproductive health services for women and men; provision of services for the special needs of adolescents; closure of the gender gap in education; and empowerment of women via education, health care, and economic options. The CEDPA network of alumnae from 30 countries had worked over the 3 years prior to the conference for the inclusion of women's priorities in policies and to achieve consensus among the government and NGO caucuses. 14 alumnae, including Peggy Curlin (CEDPA President and US delegate), were appointed to their countries' delegations and directly influenced the Programme of Action. The NGO Forum provided a place to exchange experiences and expertise; CEDPA mounted an exhibit, "Empowering Women." The network's theme was "Access, Choice, and Participation." With support from the United Nations Population Fund, CEDPA developed a manual, "After Cairo: A Handbook on Advocacy for Women Leaders," which has been distributed at training sessions and workshops and was translated into French (with support from the US Agency for International Development in Mali) for distribution at the Dakar conference in November in preparation for the World Conference on Women. CEDPA and The Global Committee for Cairo honored the secretary-general of the conference, Dr. Nafis Sadik, for her leadership of the ICPD and UNFPA, and Aziza Hussein, co-chair of the NGO steering committee, at a luncheon; Dr. Sadik

  1. Autism Research: Prospects and Priorities.

    ERIC Educational Resources Information Center

    Rutter, Michael

    1996-01-01

    Research prospects and priorities in autism are discussed with respect to: (1) diagnosis, classification, and epidemiology; (2) clinical research; (3) neuropsychological research; (4) genetics; (5) structural and functional brain imaging; (6) postmortem studies; (7) other biological research; and (8) treatment research. Application of research…

  2. Management Priorities of College Presidents.

    ERIC Educational Resources Information Center

    Patrick, Cathleen; Caruthers, J. Kent

    All U.S. college and university presidents were surveyed in 1979 to determine their priorities among planning and management improvements at their institutions. Questionnaires were mailed in December 1978 to all chief executive officers (president or chancellor), or chief executive officer for a system of colleges, universities, and central…

  3. Systemwide Communications Plan and Priorities.

    ERIC Educational Resources Information Center

    Reed, Ann

    The Board of Governors of the California Community Colleges has repeatedly identified the strengthening of communications as a key component to developing the California Community Colleges (CCC) as a system. The genesis of communications planning, activities and priorities took place in 1989 with the Burson-Marsteller Communications Action Plan,…

  4. Science Indicators and Science Priorities.

    ERIC Educational Resources Information Center

    Brooks, Harvey

    1982-01-01

    Discusses science/society interface and difficulties involved in developing realistic science indicators. Topics include: intrinsic vs. extrinsic indicators; four problems society faces as a result of technological activities (toxic chemicals, radioactive wastes, auto safety, cancer); research and development (R&D) priorities; international…

  5. Priority Education Zones in Mauritius

    ERIC Educational Resources Information Center

    Kumar, Mahadeo Santosh; Gurrib, Mahomed Aniff

    2008-01-01

    This article discusses the Priority Education Zones project (ZEP) in Mauritius. The original and innovative dimensions of the project are described, together with the difficulties encountered during the setting-up of the ZEP schools. The article covers five main issues: the status of the ZEP project; the minimal conditions for success; the…

  6. China offshore has top priority

    SciTech Connect

    Cornitius, T.A.

    1983-11-01

    Joint venture development of offshore petroleum reserves has top priority in the mammoth effort to modernize the People's Republic of China. While the country works to overcome a critical shortage of skilled personnel, export of oil, coal, consumer goods, and metals will finance technological imports.

  7. Enrollees Choose Priorities for Medicare

    ERIC Educational Resources Information Center

    Danis, Marion; Biddle, Andrea K.; Goold, Susan Dorr

    2004-01-01

    Purpose: The purpose of this study was to demonstrate the feasibility and results of ascertaining Medicare enrollees' priorities for insured medical benefits. Design and Methods: Structured group exercises were conducted with Medicare enrollees from clinical and community settings in central North Carolina. By participating in a decision exercise,…

  8. Science Indicators and Science Priorities.

    ERIC Educational Resources Information Center

    Brooks, Harvey

    1982-01-01

    Discusses science/society interface and difficulties involved in developing realistic science indicators. Topics include: intrinsic vs. extrinsic indicators; four problems society faces as a result of technological activities (toxic chemicals, radioactive wastes, auto safety, cancer); research and development (R&D) priorities; international…

  9. Priorities Statements of Community Colleges.

    ERIC Educational Resources Information Center

    Illinois Community Coll. Board, Springfield.

    Each year since 1994, the 52 community colleges in Illinois prepare priority statements detailing specific college objectives for the current fiscal year (FY). This report provides the third update of the colleges' statements, covering FY 1998. Brief statements, from one to four pages, are provided for the following colleges: Belleville Area…

  10. A Delphi study of district nursing research priorities in Australia.

    PubMed

    Annells, Merilyn; Deroche, Monique; Koch, Tina; Lewin, Gill; Lucke, Jayne

    2005-02-01

    This study, using a Delphi approach, sought the opinion of a self-selected panel of 320 district nurses regarding research priorities for district nursing in Australia. Over three rounds of questionnaires, the 419 research clinical problem areas requiring research as suggested by the panel were each rated in importance by the panel and then ranked through analysis from high to low average rating scores, thereby, whittling down the list to the top 15% (68) research questions and to a final list of the top 10 research priorities overall. Research questions focusing on discharge planning are dominant in these top 10 priorities, with documentation issues the second most common focus. Other foci in the top 10 priorities are staffing, aged care, palliative care, and assessment. The organization-specific top 10 research priorities focus on wound care, funding, education, and communication issues. Additionally, the top 68 priorities, which are either finitely practice-based or contextual-issues research questions, were categorized into 20 themes. The results will hopefully lead to scarce human and financial resources being directed to practice-relevant research programs that will facilitate improved health for district nursing (primarily home-nursing) clients in Australia and elsewhere.

  11. Research priorities for parenting and child health: a Delphi study.

    PubMed

    Hauck, Yvonne; Kelly, Robyn Gail; Fenwick, Jennifer

    2007-07-01

    This paper is a report of a study to identify research priorities of clinical staff working with families at a Western Australian centre for parenting. Australian centres for parenting focus on children's needs while working in partnership with parents, families and their communities. These agencies incorporate primary healthcare strategies in their unique approach with families. Clinicians' research priorities at these centres have not been explored in an Australian context. In 2005, a Delphi study was conducted in which clinicians were asked to provide a list of five important issues relating to care provided to children, parents and their families. Research topics identified were then ranked for their importance to the family and clinicians. Finally, the top 10 research topics were ranked for priority. In round 1, 148 research topics were identified. Thirty-six topics were removed, due to the availability of existing evidence. Content analysis was used to collapse statements into 26 research questions, which were further classified into seven categories: parenting issues; sleep and settling issues; postnatal depression; evaluation and impact of programmes; staffing issues; centre marketing services and others. Issues relating to sleep and settling and postnatal depression were rated as top research priorities. The priorities of clinicians working with families provide research direction for this Western Australian centre and potentially other centres in Australia and similar settings elsewhere in the world. The Delphi approach in determining clinicians' perceptions of relevant research areas may be useful to direct research in other contexts.

  12. Quantum Process Algebra with Priorities

    NASA Astrophysics Data System (ADS)

    Ren, Xingtian; Wang, Yong; Dai, Guiping

    2017-08-01

    One of the most fascinating characteristics is the modularity of ACP (Algebra of Communicating Processes), that is, ACP can be extended easily. qACP also inherents the modularity characteristics of ACP. By introducing new operators or new constants, qACP can have more properties. In this paper, we extend the quantum process algebra qACP with priorities support in an elegant way. And we obtain the soundness and completeness of the extension.

  13. Attention, Automaticity and Priority Learning

    DTIC Science & Technology

    1991-01-01

    with control elements that modulate the flow of of attention limited to being one thing at a time . However, with practice in consistent tasks, automatic...is presented to the network,apriontyvector senung non- attentional factors, plus (ii) search time S, which is evoked at the priority layer. The network... attentional companson (50 msec) from total reaction time for :ayer activaions by feedback from the comparator module, memory set size one (a) at Days

  14. Defining Priorities for Future Research: Results of the UK Kidney Transplant Priority Setting Partnership

    PubMed Central

    Metcalfe, Leanne; O’Donoghue, Katriona; Ball, Simon T.; Beale, Angela; Beale, William; Hilton, Rachel; Hodkinson, Keith; Lipkin, Graham W.; Loud, Fiona; Marson, Lorna P.; Morris, Peter J.

    2016-01-01

    transplant process, including access to transplantation, living donation, organ preservation, post-transplant care and management of the failing transplant. This list of priorities will provide an invaluable resource for researchers and funders to direct future activity. PMID:27776143

  15. Priorities in pediatric epilepsy research

    PubMed Central

    Baca, Christine B.; Loddenkemper, Tobias; Vickrey, Barbara G.; Dlugos, Dennis

    2013-01-01

    The Priorities in Pediatric Epilepsy Research workshop was held in the spirit of patient-centered and patient-driven mandates for developing best practices in care, particularly for epilepsy beginning under age 3 years. The workshop brought together parents, representatives of voluntary advocacy organizations, physicians, allied health professionals, researchers, and administrators to identify priority areas for pediatric epilepsy care and research including implementation and testing of interventions designed to improve care processes and outcomes. Priorities highlighted were 1) patient outcomes, especially seizure control but also behavioral, academic, and social functioning; 2) early and accurate diagnosis and optimal treatment; 3) role and involvement of parents (communication and shared decision-making); and 4) integration of school and community organizations with epilepsy care delivery. Key factors influencing pediatric epilepsy care included the child's impairments and seizure presentation, parents, providers, the health care system, and community systems. Care was represented as a sequential process from initial onset of seizures to referral for comprehensive evaluation when needed. We considered an alternative model in which comprehensive care would be utilized from onset, proactively, rather than reactively after pharmacoresistance became obvious. Barriers, including limited levels of evidence about many aspects of diagnosis and management, access to care—particularly epilepsy specialty and behavioral health care—and implementation, were identified. Progress hinges on coordinated research efforts that systematically address gaps in knowledge and overcoming barriers to access and implementation. The stakes are considerable, and the potential benefits for reduced burden of refractory epilepsy and lifelong disabilities may be enormous. PMID:23966254

  16. Priority Planetary Science Missions Identified

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-03-01

    The U.S. National Research Council's (NRC) planetary science decadal survey report, released on 7 March, lays out a grand vision for priority planetary science missions for 2013-2022 within a tightly constrained fiscal environment. The cost-conscious report, issued by NRC's Committee on the Planetary Science Decadal Survey, identifies high-priority flagship missions, recommends a number of potential midsized missions, and indicates support for some smaller missions. The report states that the highest-priority flagship mission for the decade is the Mars Astrobiology Explorer-Cacher (MAX-C)—the first of three components of a NASA/European Space Agency Mars sample return campaign—provided that the mission scope can be reduced so that MAX-C costs no more than $2.5 billion. The currently estimated mission cost of $3.5 billion “would take up a disproportionate near-term share of the overall budget for NASA's Planetary Science Division,” the report notes.

  17. 7 CFR 3430.704 - Project types and priorities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ADMINISTRATIVE PROVISIONS Biomass Research and Development Initiative § 3430.704 Project types and priorities. (a) Technical Topic Areas. Biomass Research and Development Initiative (BRDI) awards shall be directed (in consultation with the Biomass Research and Development Board, the Administrator of the Environmental Protection...

  18. 7 CFR 3430.704 - Project types and priorities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ADMINISTRATIVE PROVISIONS Biomass Research and Development Initiative § 3430.704 Project types and priorities. (a) Technical Topic Areas. Biomass Research and Development Initiative (BRDI) awards shall be directed (in consultation with the Biomass Research and Development Board, the Administrator of the Environmental Protection...

  19. 7 CFR 3430.704 - Project types and priorities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ADMINISTRATIVE PROVISIONS Biomass Research and Development Initiative § 3430.704 Project types and priorities. (a) Technical Topic Areas. Biomass Research and Development Initiative (BRDI) awards shall be directed (in consultation with the Biomass Research and Development Board, the Administrator of the Environmental Protection...

  20. 7 CFR 3430.704 - Project types and priorities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ADMINISTRATIVE PROVISIONS Biomass Research and Development Initiative § 3430.704 Project types and priorities. (a) Technical Topic Areas. Biomass Research and Development Initiative (BRDI) awards shall be directed (in consultation with the Biomass Research and Development Board, the Administrator of the Environmental Protection...

  1. Is the New Item Priority Effect an Experimental Artifact?

    ERIC Educational Resources Information Center

    Andre, Thomas

    This research was directed at determining whether the new item priority (NIP) effect in free recall was a result of an experimental artifact produced by the joint action of the serial position effect and the randomization of items over trials, or a consequence of a strategy of recalling newer items before older ones. In the experiment, subjects…

  2. Educational Priorities for the Not-So-Gay 90's.

    ERIC Educational Resources Information Center

    Pulliam, John D.

    1981-01-01

    The author views education's current basic skills and business-directed thrust as ultimately nonproductive to the first society in history which can offer material comfort to the majority. He identifies nine educational priorities which will lead beyond materialism to "human wholeness." (Part of a theme issue on the future in education.) (SJL)

  3. Prostitutes and AIDS: a health department priority?

    PubMed Central

    Rosenberg, M J; Weiner, J M

    1988-01-01

    With increasing competition for resources, health departments are faced with the question of whether to target female prostitutes as a high priority component of AIDS prevention strategy. Prostitutes are considered to be a reservoir for transmission of certain sexually transmitted diseases (STDs). However, a variety of studies suggest that human immunodeficiency virus (HIV) infection in prostitutes follows a different pattern than that for STDs: HIV infection in non-drug using prostitutes tends to be low or absent, implying that sexual activity alone does not place them at high risk, while prostitutes who use intravenous drugs are far more likely to be infected with HIV. Emerging data from heterosexual groups similarly suggest a low rate of heterosexual transmission, particularly from women to men. Prostitutes who do not use intravenous drugs probably face their highest risk from steady partners who may be infected with HIV and other STDs and with whom barrier protection is generally not used. Nevertheless, there are good reasons for health departments to place high priority on prevention efforts directed to prostitutes: 1) prostitutes often have other risky behaviors such as drug use; and 2) prostitutes are reachable, being a group which is already in the health care system administered by health departments. PMID:3279838

  4. Perinatal Substance Abuse: What's Best for the Children?

    ERIC Educational Resources Information Center

    Poulsen, Marie Kanne

    This report, which is based on the work of the Perinatal Substance Exposure Think Tanks, establishes priorities for statewide services in California to young children who are prenatally exposed to alcohol and drugs. Although the report focuses on the developmental needs of children, it also examines efforts to provide prevention and treatment…

  5. 77 FR 65912 - Priority Mail Contract

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-31

    ... Priority Mail Contract AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recent Postal Service filing concerning an amendment to Priority Mail Contract 19. This notice... existing Priority Mail Contract 19 subject to this docket.\\1\\ The Postal Service includes one attachment in...

  6. 7 CFR 632.12 - Funding priorities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Funding priorities. 632.12 Section 632.12 Agriculture... AGRICULTURE LONG TERM CONTRACTING RURAL ABANDONED MINE PROGRAM Qualifications § 632.12 Funding priorities. (a) All eligible applications within a State are to be assigned a funding priority and subpriority...

  7. 7 CFR 632.12 - Funding priorities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Funding priorities. 632.12 Section 632.12 Agriculture... AGRICULTURE LONG TERM CONTRACTING RURAL ABANDONED MINE PROGRAM Qualifications § 632.12 Funding priorities. (a) All eligible applications within a State are to be assigned a funding priority and subpriority...

  8. 10 CFR 580.03 - Curtailment priorities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Curtailment priorities. 580.03 Section 580.03 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) CURTAILMENT PRIORITIES FOR ESSENTIAL AGRICULTURAL USES § 580.03 Curtailment priorities. (a) Notwithstanding any provision of law...

  9. 10 CFR 580.03 - Curtailment priorities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Curtailment priorities. 580.03 Section 580.03 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) CURTAILMENT PRIORITIES FOR ESSENTIAL AGRICULTURAL USES § 580.03 Curtailment priorities. (a) Notwithstanding any provision of law...

  10. 7 CFR 3431.14 - Priority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Priority. Pursuant to NVMSA, the Secretary will give priority to agreements with veterinarians for the practice of food animal medicine in veterinarian shortage situations, as determined by the Secretary. The Secretary may establish additional criteria in the RFA for assigning priority levels to veterinarian...

  11. 7 CFR 3431.14 - Priority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Priority. Pursuant to NVMSA, the Secretary will give priority to agreements with veterinarians for the practice of food animal medicine in veterinarian shortage situations, as determined by the Secretary. The Secretary may establish additional criteria in the RFA for assigning priority levels to veterinarian...

  12. 7 CFR 3431.14 - Priority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Priority. Pursuant to NVMSA, the Secretary will give priority to agreements with veterinarians for the practice of food animal medicine in veterinarian shortage situations, as determined by the Secretary. The Secretary may establish additional criteria in the RFA for assigning priority levels to veterinarian...

  13. 7 CFR 3431.14 - Priority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Priority. Pursuant to NVMSA, the Secretary will give priority to agreements with veterinarians for the practice of food animal medicine in veterinarian shortage situations, as determined by the Secretary. The Secretary may establish additional criteria in the RFA for assigning priority levels to veterinarian...

  14. 48 CFR 873.103 - Priority sources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Priority sources. 873.103... SUPPLEMENTARY REGULATIONS SIMPLIFIED ACQUISITION PROCEDURES FOR HEALTH-CARE RESOURCES 873.103 Priority sources.... 46-48c) and FAR Subpart 8.7, there are no priority sources for the acquisition of...

  15. 48 CFR 873.103 - Priority sources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Priority sources. 873.103... SUPPLEMENTARY REGULATIONS SIMPLIFIED ACQUISITION PROCEDURES FOR HEALTH-CARE RESOURCES 873.103 Priority sources.... 46-48c) and FAR Subpart 8.7, there are no priority sources for the acquisition of...

  16. 7 CFR 632.12 - Funding priorities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGRICULTURE LONG TERM CONTRACTING RURAL ABANDONED MINE PROGRAM Qualifications § 632.12 Funding priorities. (a.... Assignment of a priority and subpriority establishes the order in which the proposed reclamation work will be... extreme danger. (3) Priority 3. Restoration of the land and water resources and the environment where...

  17. 7 CFR 1777.13 - Project priority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Project priority. 1777.13 Section 1777.13 Agriculture... (CONTINUED) SECTION 306C WWD LOANS AND GRANTS § 1777.13 Project priority. Paragraphs (a) through (d) of this... applicant eligibility and the proposed project's priority for available funds. Applicants determined...

  18. 7 CFR 1777.13 - Project priority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Project priority. 1777.13 Section 1777.13 Agriculture... (CONTINUED) SECTION 306C WWD LOANS AND GRANTS § 1777.13 Project priority. Paragraphs (a) through (d) of this... applicant eligibility and the proposed project's priority for available funds. Applicants determined...

  19. 7 CFR 1778.7 - Project priority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Project priority. 1778.7 Section 1778.7 Agriculture... (CONTINUED) EMERGENCY AND IMMINENT COMMUNITY WATER ASSISTANCE GRANTS § 1778.7 Project priority. Paragraph (d... to determine the proposed project's priority for available funds. (b) State Office review. All...

  20. 7 CFR 1777.13 - Project priority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Project priority. 1777.13 Section 1777.13 Agriculture... (CONTINUED) SECTION 306C WWD LOANS AND GRANTS § 1777.13 Project priority. Paragraphs (a) through (d) of this... eligibility and the proposed project's priority for available funds. Applicants determined ineligible will be...

  1. 7 CFR 1778.7 - Project priority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Project priority. 1778.7 Section 1778.7 Agriculture... (CONTINUED) EMERGENCY AND IMMINENT COMMUNITY WATER ASSISTANCE GRANTS § 1778.7 Project priority. Paragraph (d... to determine the proposed project's priority for available funds. (b) State Office review. All...

  2. 7 CFR 1778.7 - Project priority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Project priority. 1778.7 Section 1778.7 Agriculture... (CONTINUED) EMERGENCY AND IMMINENT COMMUNITY WATER ASSISTANCE GRANTS § 1778.7 Project priority. Paragraph (d... to determine the proposed project's priority for available funds. (b) State Office review....

  3. 49 CFR 260.7 - Priority consideration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Priority consideration. 260.7 Section 260.7... REHABILITATION AND IMPROVEMENT FINANCING PROGRAM Overview § 260.7 Priority consideration. When evaluating applications, the Administrator will give priority consideration (but not necessarily in the following...

  4. 48 CFR 873.103 - Priority sources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Priority sources. 873.103... SUPPLEMENTARY REGULATIONS SIMPLIFIED ACQUISITION PROCEDURES FOR HEALTH-CARE RESOURCES 873.103 Priority sources.... 46-48c) and FAR Subpart 8.7, there are no priority sources for the acquisition of health-care...

  5. 48 CFR 873.103 - Priority sources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Priority sources. 873.103... SUPPLEMENTARY REGULATIONS SIMPLIFIED ACQUISITION PROCEDURES FOR HEALTH-CARE RESOURCES 873.103 Priority sources.... 46-48c) and FAR Subpart 8.7, there are no priority sources for the acquisition of health-care...

  6. 48 CFR 8.603 - Purchase priorities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the following priorities: (a) Supplies. (1) Federal Prison Industries, Inc. (41 U.S.C. 8504). (2... priorities. FPI and nonprofit agencies participating in the AbilityOne Program under 41 U.S.C. chapter 85... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Purchase priorities. 8.603...

  7. 48 CFR 8.704 - Purchase priorities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... priorities: (1) Supplies: (i) Federal Prison Industries, Inc. (41 U.S.C. 8504). (ii) AbilityOne participating... Blind or Severely Disabled 8.704 Purchase priorities. (a) 41 U.S.C. chapter 85 requires the Government... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Purchase priorities. 8.704...

  8. Anticancer substances of mushroom origin.

    PubMed

    Ivanova, T S; Krupodorova, T A; Barshteyn, V Y; Artamonova, A B; Shlyakhovenko, V A

    2014-06-01

    The present status of investigations about the anticancer activity which is inherent to medicinal mushrooms, as well as their biomedical potential and future prospects are discussed. Mushroom products and extracts possess promising immunomodulating and anticancer effects, so the main biologically active substances of mushrooms responsible for immunomodulation and direct cytoto-xicity toward cancer cell lines (including rarely mentioned groups of anticancer mushroom proteins), and the mechanisms of their antitumor action were analyzed. The existing to date clinical trials of mushroom substances are mentioned. Mushroom anticancer extracts, obtained by the different solvents, are outlined. Modern approaches of cancer treatment with implication of mushroom products, including DNA vaccinotherapy with mushroom immunomodulatory adjuvants, creation of prodrugs with mushroom lectins that can recognize glycoconjugates on the cancer cell surface, development of nanovectors etc. are discussed. The future prospects of mushroom anticancer substances application, including chemical modification of polysaccharides and terpenoids, gene engineering of proteins, and implementation of vaccines are reviewed.

  9. Monitoring of selected priority and emerging contaminants in the Guadalquivir River and other related surface waters in the province of Jaén, South East Spain.

    PubMed

    Robles-Molina, José; Gilbert-López, Bienvenida; García-Reyes, Juan F; Molina-Díaz, Antonio

    2014-05-01

    The province of Jaén counts with four natural parks, numerous rivers, reservoirs and wetlands; moreover, it is probably the region with higher olive oil production in the world, which makes this zone a proper target to be studied based on the European Water Framework Directive 2000/60/CE. The aim of this survey is to monitor a total number of 373 compounds belonging to different families (pesticides, PAHs, nitrosamines, drugs of abuse, pharmaceuticals and life-style compounds) in surface waters located at different points of the province of Jaén. Among these compounds some priority organic substances (regulated by the EU Directive 2008/105/EC) and pollutants of emerging concern (not regulated yet) can be found. A liquid chromatography electrospray time-of-flight mass spectrometry (LC-TOFMS) method covering 340 compounds was developed and applied, together with a gas chromatography triple-quadrupole mass spectrometry (GC-MS/MS) method which enabled the analysis of 63 organic contaminants (30 of these compounds are analyzed by LC-TOFMS as well). From April 2009 to November 2010 a total of 83 surface water samples were collected (rivers, reservoirs and wetlands). In this period numerous organic contaminants were detected, most of them at the ng L(-1) level. The most frequently priority substances found were chlorpyrifos ethyl, diuron and hexachlorobenzene. Within the other groups, the most frequently detected compounds were: terbuthylazine, oxyfluorfen, desethyl terbuthylazine, diphenylamine (pesticide family); fluorene, phenanthrene, pyrene (PAHs group), codeine, paracetamol (pharmaceuticals compounds) and caffeine, nicotine (life-style compounds). As is could be expected, the total concentration of emerging contaminants is distinctly larger than that of priority pollutants, highlighting the importance of continuing with the study of their presence, fate and effects in aquatic environments. However, concentration levels (at the ng per liter level) are low in

  10. The use of the "highest priority critically important antimicrobials" in 75 Austrian pig farms--evaluation of on-farm drug application data.

    PubMed

    Trauffler, Martine; Obritzhauser, Walter; Raith, Johannes; Fuchs, Klemens; Köfer, Josef

    2014-01-01

    The World Health Organization lists antimicrobial substances which are essential for the treatment of specific infections in humans as "highest priority critically important antimicrobials" (HPCIAs): macrolides, fluoroquinolones, 3rd and 4th generation cephalosporins as well as glycopeptid antibacterials. The use of these substances in livestock husbandry should be restricted in order to minimise the risk of antimicrobial resistance. To date, there is little knowledge about the amounts of HPCIAs used in animal husbandry and the different animal species and diagnoses these antimicrobials are prescribed for. In a retrospective study, drug application data recorded from 2008 until 2011 from 75 conventional pig farms were evaluated. Data were assessed directly by the farmer at farm-level. The annual antimicrobial consumption was expressed in "weight of active substance(s) in [mg]" and "number of Daily Doses". Results were referred to the animal biomass, evaluated per pig age class (piglets, weaners, fattening pigs < 60 kg biomass; fattening pigs > 60 kg biomass, sows, boars) and broken down to some variables such as the substance class and the therapy indication. The focus was especially laid on the HPCIAs. The total usage of the HPCIAs in the study population was on average 3.0 mg/ kg/year; 1.1 UDD(kg)/kg/year; 0.2 ADD(kg)/kg/year and 0.6 PrDD(kg)/kg/year. This represents about 9%, 22%, 12% and 22% of total antimicrobial consumption, respectively, depending on the unit of measurement. Fattening farms showed the highest consumption of the named substances. The main part of the HPCIAs (nADD(kg)/year) was applied to weaners, piglets and fattening pigs < 60 kg. They played an important role in the therapies of piglets (approximately 40% of the total antimicrobial consumption in piglets). Macrolides played the major role within the HPCIAs and were mainly used for digestive tract diseases. A not negligible portion of macrolides was prescribed for metaphylactic and

  11. 40 CFR 35.2015 - State priority system and project priority list.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... achieve optimum water quality management consistent with the goals and requirements of the Act. All..., needs and priorities set forth in areawide water quality management plans, and any other factors... priority to projects in priority water quality areas. The priority system may also include...

  12. 40 CFR 35.2015 - State priority system and project priority list.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... achieve optimum water quality management consistent with the goals and requirements of the Act. All..., needs and priorities set forth in areawide water quality management plans, and any other factors... priority to projects in priority water quality areas. The priority system may also include...

  13. 40 CFR 35.2015 - State priority system and project priority list.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false State priority system and project... State priority system and project priority list. (a) General. The Regional Administrator will award grant assistance from annual allotments to projects on a State project priority list developed in...

  14. 40 CFR 35.2015 - State priority system and project priority list.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false State priority system and project... State priority system and project priority list. (a) General. The Regional Administrator will award grant assistance from annual allotments to projects on a State project priority list developed in...

  15. Accounting and Financial Planning--Top Priorities for School Business Administrators.

    ERIC Educational Resources Information Center

    Walters, Donald L.

    Success for the business administrator depends largely on ability to identify priorities and to direct time, energy, and know-how accordingly. This study attempted to find out the priorities of the tasks of accounting and financial planning for school business administrators and the precise nature of the school business administrator's…

  16. Accounting and Financial Planning--Top Priorities for School Business Administrators.

    ERIC Educational Resources Information Center

    Walters, Donald L.

    Success for the business administrator depends largely on ability to identify priorities and to direct time, energy, and know-how accordingly. This study attempted to find out the priorities of the tasks of accounting and financial planning for school business administrators and the precise nature of the school business administrator's…

  17. Perioperative leadership: managing change with insights, priorities, and tools.

    PubMed

    Taylor, David L

    2014-07-01

    The personal leadership of the perioperative director is a critical factor in the success of any change management initiative. This article presents an approach to perioperative nursing leadership that addresses obstacles that prevent surgical departments from achieving high performance in clinical and financial outcomes. This leadership approach consists of specific insights, priorities, and tools: key insights include self-understanding of personal barriers to leadership and accuracy at understanding economic and strategic considerations related to the OR environment; key priorities include creating a customer-centered organization, focusing on process improvement, and concentrating on culture change; and key tools include using techniques (e.g., direct engagement, collaborative leadership) to align surgical organizations with leadership priorities and mitigate specific perioperative management risks. Included in this article is a leadership development plan for perioperative directors.

  18. Substance use and multiculturalism.

    PubMed

    Adrian, M

    1996-01-01

    This paper reviews intercultural variability of substance use behaviors, including availability of international statistics on consumption of alcohol and other drugs, as well as the use of drugs available locally only. Within a conceptual framework of intercultural relations, it considers the history of transcultural spread of substance use behaviors and possible reactions to the introduction of new drugs within a culture or jurisdiction, including illustrations of the "law of alien poisons." Although intercultural views of substance use have generally concentrated on majority groups' views of substance use in minority groups, minority and non-Western views of substance use need to be considered in the context of increasing international and intercultural communications that increase the rate at which substance use behaviors spread. Both Western and non-Western experiences with substance use and misuse must be taken into account so that better interventions can be developed to deal with addictions and other substance-related problems.

  19. TSCA Chemical Substance Inventory

    EPA Pesticide Factsheets

    Section 8 (b) of the Toxic Substances Control Act (TSCA) requires EPA to compile, keep current, and publish a list of each chemical substance that is manufactured or processed in the United States for TSCA uses.

  20. Substance Abuse and Trauma.

    PubMed

    Simmons, Shannon; Suárez, Liza

    2016-10-01

    There is a strong, bidirectional link between substance abuse and traumatic experiences. Teens with cooccurring substance use disorders (SUDs) and posttraumatic stress disorder (PTSD) have significant functional and psychosocial impairment. Common neurobiological foundations point to the reinforcing cycle of trauma symptoms, substance withdrawal, and substance use. Treatment of teens with these issues should include a systemic and integrated approach to both the SUD and the PTSD.

  1. Agricultural aviation user requirement priorities

    NASA Technical Reports Server (NTRS)

    Kaplan, R. L.; Meeland, T.; Peterson, J. E.

    1977-01-01

    The results are given of a research project pertaining to the development of agricultural aviation user requirement priorities. The raw data utilized in the project was obtained from the National Agricultural Aviation Association. A specially configured poll, developed by the Actuarial Research Corporation was used to solicit responses from NAAA members and others. The primary product of the poll is the specification of seriousness as determined by the respondents for some selected agricultural aviation problem areas identified and defined during the course of an intensive analysis by the Actuarial Research Corporation.

  2. Violence against Native Women in Substance Abuse Treatment

    ERIC Educational Resources Information Center

    Saylors, Karen; Daliparthy, Nalini

    2006-01-01

    Many mental health problems among substance abusing populations are directly linked to high rates of abuse and trauma. There is increasing evidence of associations between childhood physical and sexual abuse to adult substance use and HIV-risk behavior. The relationship of abuse, mental health problems, substance abuse, and high-risk sexual…

  3. Substance Abuse Prevention Education Program. 1974-75 Evaluation Report.

    ERIC Educational Resources Information Center

    Michigan State Dept. of Education, Lansing.

    The Substance Abuse Prevention Education (SAPE) program aims at: (1) having a direct impact on young people to prevent substance abuse; (2) working with school teachers, parents, and other citizens to develop specific skills that will facilitate substance abuse prevention; and (3) providing program participants with better understanding of the…

  4. New Directions for Substance-Abuse Prevention

    ERIC Educational Resources Information Center

    Anderson, David S.

    2011-01-01

    Across the nation and for a very long time, campuses and students have been plagued by drug and alcohol abuse. And it seems that many of our efforts to address that abuse, while necessary, have been woefully insufficient to the task. This article describes the nature and significance of the problem, examines current strategies for addressing it,…

  5. New Directions for Substance-Abuse Prevention

    ERIC Educational Resources Information Center

    Anderson, David S.

    2011-01-01

    Across the nation and for a very long time, campuses and students have been plagued by drug and alcohol abuse. And it seems that many of our efforts to address that abuse, while necessary, have been woefully insufficient to the task. This article describes the nature and significance of the problem, examines current strategies for addressing it,…

  6. Substance Abuse in Rural Areas

    MedlinePlus

    ... Guide Rural Health Topics & States Topics View more Substance Abuse in Rural Areas Substance abuse has long been ... are some options to reduce it? What is substance abuse and what are the signs of substance abuse? ...

  7. Elder Abuse and Substance Abuse

    MedlinePlus

    ... to: What is Elder Abuse? Elder Abuse and Substance Abuse Substance abuse has been identified as the most frequently cited ... victim and/or the perpetrator who has the substance abuse problem. Substance abuse is believed to be a ...

  8. Substance Identification Information from EPA's Substance Registry

    EPA Pesticide Factsheets

    The Substance Registry Services (SRS) is the authoritative resource for basic information about substances of interest to the U.S. EPA and its state and tribal partners. Substances, particularly chemicals, can have many valid synonyms. For example, toluene, methyl benzene, and phenyl methane, are commonly used names for the same chemical. EPA programs collect environmental data for this chemical using each of these names, plus others. This diversity leads to problems when a user is looking for programmatic data for toluene but is unaware that the data is stored under the synonym methyl benzene. For each substance, the SRS identifies the statutes, EPA programs, as well as organization external to EPA, that track or regulate that substance and the synonym used by that statute, EPA program or external organization. Besides standardized information for each chemical, such as the Chemical Abstracts Services name and the Chemical Abstracts Number and the EPA Registry Name (the EPA standard name), the SRS also includes additional information, such as molecular weight and molecular formula. Additionally, an SRS Internal Tracking Number uniquely identifies each substance, enabling cross-walking between synonyms. EPA is providing a large .ZIP file providing the SRS data in CSV format, and a separate small metadata file in XML containing the field names and definitions.

  9. Reconnaissance of toxic substances in the Jordan River, Salt Lake County, Utah

    SciTech Connect

    Thompson, K.R.

    1984-01-01

    A reconnaissance of toxic substances in the Jordan River, Salt Lake County, Utah, was made during July 1980 to October 1982 as part of a larger study of the river that included studies of sanitary quality, dissolved oxygen, and turbidity. Samples for toxic substances were collected at five sites on the Jordan River, at three major tributaries, and at six storm conduits. The toxic substance that most frequently exceeded State standards was total mercury. About 78% of the 138 samples for total mercury exceeded the State standard of 0.05 microgram per liter. Other toxic substances that exceeded State standards were: ammonia, cadmium, copper, zinc, and lead. One sample for cyanide and one for iron also exceeded State standards. The diversity of toxic substances with concentrations large enough to cause them to be problems increased from the upstream sampling site at the Jordan Narrows to the next two downstream sites at 9000 South and 5800 South Streets. Concentrations of trace elements in stream-bottom materials also increased in a downstream direction. Substantial increases first were observed at 5800 South Street, and they were sustained throughout the downstream study area. Iron is transported in the greatest quantity of all the trace elements studied, with a mean load of 110 pounds per day. Notable loads of barium, boron, lead, and zinc also are transported by the river. DDD, DDE, DDT, dieldrin, heptachlor, methoxychlor, PCB, and 2,4-D were detected in bottom materials; and DDE, Silvex, and 2,4-D were detected in water samples. Chloroform was detected in the storm conduits that empty into the Jordan River. Several metals and phenol also were detected in the samples analyzed for priority pollutants. 15 refs., 1 fig., 14 tabs.

  10. Priorities for global felid conservation.

    PubMed

    Dickman, Amy J; Hinks, Amy E; Macdonald, Ewan A; Burnham, Dawn; Macdonald, David W

    2015-06-01

    Conservation resources are limited, necessitating prioritization of species and locations for action. Most prioritization approaches are based solely on biologically relevant characteristics of taxa or areas and ignore geopolitical realities. Doing so risks a poor return on conservation investment due to nonbiological factors, such as economic or political instability. We considered felids, a taxon which attracts intense conservation attention, to demonstrate a new approach that incorporates both intrinsic species traits and geopolitical characteristics of countries. We developed conservation priority scores for wild felids based on their International Union for Conservation of Nature status, body mass, habitat, range within protected area, evolutionary distinctiveness, and conservation umbrella potential. We used published data on governance, economics and welfare, human population pressures, and conservation policy to assign conservation-likelihood scores to 142 felid-hosting countries. We identified 71 countries as high priorities (above median) for felid conservation. These countries collectively encompassed all 36 felid species and supported an average of 96% of each species' range. Of these countries, 60.6% had below-average conservation-likelihood scores, which indicated these countries are relatively risky conservation investments. Governance was the most common factor limiting conservation likelihood. It was the major contributor to below-median likelihood scores for 62.5% of the 32 felid species occurring in lower-likelihood countries. Governance was followed by economics for which scores were below median for 25% of these species. An average of 58% of species' ranges occurred in 43 higher-priority lower-likelihood countries. Human population pressure was second to governance as a limiting factor when accounting for percentage of species' ranges in each country. As conservation likelihood decreases, it will be increasingly important to identify relevant

  11. USGS Toxic Substances Hydrology Program, 2010

    USGS Publications Warehouse

    Buxton, Herbert T.

    2010-01-01

    The U.S. Geological Survey (USGS) Toxic Substances Hydrology Program adapts research priorities to address the most important contamination issues facing the Nation and to identify new threats to environmental health. The Program investigates two major types of contamination problems: * Subsurface Point-Source Contamination, and * Watershed and Regional Contamination. Research objectives include developing remediation methods that use natural processes, characterizing and remediating contaminant plumes in fractured-rock aquifers, identifying new environmental contaminants, characterizing new and understudied pesticides in common pesticide-use settings, explaining mercury methylation and bioaccumulation, and developing approaches for remediating watersheds affected by active and historic mining.

  12. Research priorities for occupational radiation protection

    SciTech Connect

    Not Available

    1994-02-01

    The Subpanel on Occupational Radiation Protection Research concludes that the most urgently needed research is that leading to the resolution of the potential effects of low-level ionizing radiation. This is the primary driving force in setting appropriate radiation protection standards and in directing the emphasis of radiation protection efforts. Much has already been done in collecting data that represents a compendium of knowledge that should be fully reviewed and understood. It is imperative that health physics researchers more effectively use that data and apply the findings to enhance understanding of the potential health effects of low-level ionizing radiation and improve the risk estimates upon which current occupational radiation protection procedures and requirements depend. Research must be focused to best serve needs in the immediate years ahead. Only then will we get the most out of what is accomplished. Beyond the above fundamental need, a number of applied research areas also have been identified as national priority issues. If effective governmental focus is achieved on several of the most important national priority issues, important occupational radiation protection research will be enhanced, more effectively coordinated, and more quickly applied to the work environment. Response in the near term will be enhanced and costs will be reduced by: developing microprocessor-aided {open_quotes}smart{close_quotes} instruments to simplify the use and processing of radiation data; developing more sensitive, energy-independent, and tissue-equivalent dosimeters to more accurately quantify personnel dose; and developing an improved risk assessment technology base. This can lead to savings of millions of dollars in current efforts needed to ensure personnel safety and to meet new, more stringent occupational guidelines.

  13. Priorities for tuberculosis research: a systematic review

    PubMed Central

    Rylance, Jamie; Pai, Madhukar; Lienhardt, Christian; Garner, Paul

    2010-01-01

    Summary Reliable and relevant research can help to improve tuberculosis control worldwide. In recent years, various organisations have assessed research needs and proposed priorities for tuberculosis. We summarise existing priority statements and assess the rigour of the methods used to generate them. We found 33 documents that specifically outline priorities in tuberculosis research. The top priority areas were drug development (28 articles), diagnosis and diagnostic tests (27), epidemiology (20), health services research (16), basic research (13), and vaccine development and use (13). The most focused questions were on the treatment and prevention of multidrug-resistant tuberculosis in people co-infected with HIV. Methods used to identify these priorities were varied. Improvements can be made to ensure the process is more rigorous and transparent, and to use existing research or systematic reviews more often. WHO, Stop TB Partnership, and other organisations could adopt an incremental process of priority development, building on the existing knowledge base. PMID:21050822

  14. House Panel continues to investigate science priorities

    NASA Astrophysics Data System (ADS)

    Jones, Richard M.

    The House science committee held the second of three hearings to address priority setting in federal research funding. At the April 28 hearing, four witnesses from both the public and private sectors agreed that scientists must become more involved in setting priorities, even if the mechanisms to do so are still being developed.The lead witness, former Ohio governor Richard F. Celeste, now chairman of the Government-University-Industry Research Roundtable, contended that “priority setting is essential” but cited “deep concern about excessive planning, too much specificity in setting research priorities for fundamental research.” He said that broad participation is critically important, calling for a national forum where “institutions could discuss and compare their plans and priorities.” Over the next two years the roundtable plans a series of focus groups and national colloquia to examine priority setting and strategic planning.

  15. Priorities for tuberculosis research: a systematic review.

    PubMed

    Rylance, Jamie; Pai, Madhukar; Lienhardt, Christian; Garner, Paul

    2010-12-01

    Reliable and relevant research can help to improve tuberculosis control worldwide. In recent years, various organisations have assessed research needs and proposed priorities for tuberculosis. We summarise existing priority statements and assess the rigour of the methods used to generate them. We found 33 documents that specifically outline priorities in tuberculosis research. The top priority areas were drug development (28 articles), diagnosis and diagnostic tests (27), epidemiology (20), health services research (16), basic research (13), and vaccine development and use (13). The most focused questions were on the treatment and prevention of multidrug-resistant tuberculosis in people co-infected with HIV. Methods used to identify these priorities were varied. Improvements can be made to ensure the process is more rigorous and transparent, and to use existing research or systematic reviews more often. WHO, Stop TB Partnership, and other organisations could adopt an incremental process of priority development, building on the existing knowledge base. Copyright © 2010 Elsevier Ltd. All rights reserved.

  16. Physiotherapy Research Priorities in Switzerland: Views of the Various Stakeholders.

    PubMed

    Nast, Irina; Tal, Amir; Schmid, Stefan; Schoeb, Veronika; Rau, Barbara; Barbero, Marco; Kool, Jan

    2016-09-01

    Research priorities, defined by multiple stakeholders, can proximally facilitate the coordination of research projects and national and international cooperation and distally further improve the quality of physiotherapy practice. The aim of this study was therefore to establish physiotherapy research priorities in Switzerland considering multiple stakeholders' opinions. A mixed methods design was chosen. For a qualitative identification of physiotherapy research topics, 18 focus group discussions and 23 semi-structured interviews/written commentaries were conducted. For the quantitative analysis, 420 participants prioritized research topics using a two-round Delphi questionnaire survey. The following stakeholder groups were surveyed in the German-speaking, French-speaking and Italian-speaking regions of Switzerland: physiotherapy researchers, practitioners and educators, representatives of patient organizations, public health organizations, health insurers, physicians, nurses, occupational therapists and other health professionals, as well as physical educators. The top five overall physiotherapy research priorities identified were as follows: physiotherapy treatment, physiotherapy assessment and diagnosis, prevention, physiotherapist-patient interaction and physiotherapy professional education at the bachelor level. With regard to diagnostic groups, the highest priorities were placed on musculoskeletal disorders, neurology, orthopaedics, geriatrics and ergonomics/occupational health. Consensus was moderate to high, and only few differences between stakeholder groups were revealed. Research directly related to physiotherapy treatment is of highest priority. It should focus on diagnostic groups related to chronicity in anticipation of demographic changes. Multidisciplinary networks for research and practice, alongside sound coordination of research projects, should increase the impact of physiotherapy research. An accurate dissemination of research priorities

  17. Assessing U.S. Strategic Priorities

    DTIC Science & Technology

    1995-01-01

    derstanding of global security trends, national interests, and strategic priorities is essential to sound foreign and defense policy. The following...conflicts in the years ahead. This suggests four priorities in formulating national strategy that include, in order of importance, ensuring peace...these priorities is that the Nation may be required to reconsider its nearly two-major-regional- conflicts strategy in order to maintain a balanced

  18. 7 CFR 3431.14 - Priority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE VETERINARY MEDICINE LOAN REPAYMENT PROGRAM Administration of the Veterinary Medicine Loan Repayment Program § 3431.14 Priority. Pursuant to NVMSA, the Secretary will...

  19. Research priorities for entering the 21st century. Pacific Northwest Research Station

    SciTech Connect

    1997-01-01

    Forest Service Research and the PNW Research Station developed linked strategic plans early in 1990s that provided broad research program direction in this changing social environment. There is now a national effort within Forest Service Research to anchor this broad direction to specific themes for the next several years, based on the emergence of such issues as ecological sustain-ability and joint resource use, integration, and broadscale and multiscale dimensions. The Pacific Northwest Research Station refers to these themes as intermediate-term priorities. This paper provides a foundation for defining PNW Research Station priorities in the intermediate term (3 to 5 years) and defines 11 intermediate-term priorities.

  20. Mental health research priorities for Europe.

    PubMed

    Wykes, Til; Haro, Josep Maria; Belli, Stefano R; Obradors-Tarragó, Carla; Arango, Celso; Ayuso-Mateos, José Luis; Bitter, István; Brunn, Matthias; Chevreul, Karine; Demotes-Mainard, Jacques; Elfeddali, Iman; Evans-Lacko, Sara; Fiorillo, Andrea; Forsman, Anna K; Hazo, Jean-Baptiste; Kuepper, Rebecca; Knappe, Susanne; Leboyer, Marion; Lewis, Shôn W; Linszen, Donald; Luciano, Mario; Maj, Mario; McDaid, David; Miret, Marta; Papp, Szilvia; Park, A-La; Schumann, Gunter; Thornicroft, Graham; van der Feltz-Cornelis, Christina; van Os, Jim; Wahlbeck, Kristian; Walker-Tilley, Tom; Wittchen, Hans-Ulrich

    2015-11-01

    Mental and brain disorders represent the greatest health burden to Europe-not only for directly affected individuals, but also for their caregivers and the wider society. They incur substantial economic costs through direct (and indirect) health-care and welfare spending, and via productivity losses, all of which substantially affect European development. Funding for research to mitigate these effects lags far behind the cost of mental and brain disorders to society. Here, we describe a comprehensive, coordinated mental health research agenda for Europe and worldwide. This agenda was based on systematic reviews of published work and consensus decision making by multidisciplinary scientific experts and affected stakeholders (more than 1000 in total): individuals with mental health problems and their families, health-care workers, policy makers, and funders. We generated six priorities that will, over the next 5-10 years, help to close the biggest gaps in mental health research in Europe, and in turn overcome the substantial challenges caused by mental disorders. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. PTSD and Substance Abuse

    DTIC Science & Technology

    2014-10-01

    AD_________________ Award Number: W81XWH-10-2-0074 TITLE: PTSD and Substance Abuse PRINCIPAL...PTSD and Substance Abuse 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-10-2-0074 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Dr. Lisa M...Board, Substance Abuse and Rehabilitation 2011-pres. Editorial Board, Psychological Trauma: Theory, Research, Practice, and Policy 2014-pres

  2. PTSD and Substance Abuse

    DTIC Science & Technology

    2012-07-01

    W81XWH1020074 TITLE: PTSD and Substance Abuse PRINCIPAL INVESTIGATOR: Lisa Najavits, Ph.D. CONTRACTING...1 August 2011 – 31 July 2012 4. TITLE AND SUBTITLE PTSD and Substance Abuse 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-10...months as we then dropped Fort Jackson as a site due 6 to a change in our site PI’s role there (no longer having oversight of the substance abuse

  3. Substance use - amphetamines

    MedlinePlus

    Substance abuse - amphetamines; Drug abuse - amphetamines; Drug use - amphetamines ... PA: Elsevier; 2016:chap 50. National Institute on Drug Abuse. Methamphetamines. www.drugabuse.gov/publications/research-reports/methamphetamine/ ...

  4. Substance use - phencyclidine (PCP)

    MedlinePlus

    PCP; Substance abuse - phencyclidine; Drug abuse - phencyclidine; Drug use - phencyclidine ... PA: Elsevier; 2016:chap 50. National Institute on Drug Abuse. Research report series: Hallucinogens and dissociative drugs. Updated ...

  5. Substance Abuse Screening

    MedlinePlus

    ... the following substances have you ever used? (NON-MEDICAL USE ONLY) Tobacco products, alcoholic beverages, cannabis, cocaine, stimulants, inhalants, sedatives/hypnotics, hallucinogens, opioids, and ¿ ...

  6. Substance use - inhalants

    MedlinePlus

    Substance abuse - inhalants; Drug abuse - inhalants; Drug use - inhalants; Glue - inhalants ... symptoms and may include: Strong cravings for the drug Having mood swings from feeling depressed to agitated ...

  7. Hazardous-waste sites: Priority health conditions and research strategies--United States

    SciTech Connect

    Not Available

    1992-02-07

    Uncontrolled disposal sites containing hazardous waste and other contaminants have created national environmental problems (1). Because of potential health problems associated with the more than 33,000 hazardous-waste sites in the United States, the Agency for Toxic Substances and Disease Registry (ATSDR)--as part of its federally legislated mandate--has developed a list of seven priority health conditions (PHCs) to (1) assist in evaluating potential health risks to persons living near these sites and (2) determine program and applied human health research activities involving hazardous substances identified at the sites. This report summarizes the development and intended applications of the seven PHCs.

  8. Evaluation of the ecotoxicity of sediments from Yangtze river estuary and contribution of priority PAHs to ah receptor--mediated activities.

    PubMed

    Liu, Li; Chen, Ling; Shao, Ying; Zhang, Lili; Floehr, Tilman; Xiao, Hongxia; Yan, Yan; Eichbaum, Kathrin; Hollert, Henner; Wu, Lingling

    2014-01-01

    In this study, in vitro bioassays were performed to assess the ecotoxicological potential of sediments from Yangtze River estuary. The cytotoxicity and aryl hydrocarbon receptor (AhR)-mediated toxicity of sediment extracts with rainbow trout (Oncorhynchus mykiss) liver cells were determined by neutral red retention and 7-ethoxyresorufin-O-deethylase assays. The cytotoxicity and AhR-mediated activity of sediments from the Yangtze River estuary ranged from low level to moderate level compared with the ecotoxicity of sediments from other river systems. However, Yangtze River releases approximately 14 times greater water discharge compared with Rhine, a major river in Europe. Thus, the absolute pollution mass transfer of Yangtze River may be detrimental to the environmental quality of estuary and East China Sea. Effect-directed analysis was applied to identify substances causing high dioxin-like activities. To identify unknown substances contributing to dioxin-like potencies of whole extracts, we fractionated crude extracts by open column chromatography. Non-polar paraffinic components (F1), weakly and moderately polar components (F2), and highly polar substances (F3) were separated from each crude extract of sediments. F2 showed the highest dioxin-like activities. Based on the results of mass balance calculation of chemical toxic equivalent concentrations (TEQs), our conclusion is that priority polycyclic aromatic hydrocarbons indicated a low portion of bio-TEQs ranging from 1% to 10% of crude extracts. Further studies should be conducted to identify unknown pollutants.

  9. The Social Context of Homeless Men’s Substance Use

    PubMed Central

    Rhoades, Harmony; Wenzel, Suzanne L.; Golinelli, Daniela; Tucker, Joan S.; Kennedy, David P.; Green, Harold D.; Zhou, Annie

    2011-01-01

    Background Homeless men may be at particular risk for the negative health effects of substance use. This cross-sectional study investigates the individual and personal network risk factors associated with substance use in this vulnerable population. Methods Participants were a representative probability sample of 305 heterosexually active homeless men interviewed from meal programs in the Skid Row region of Los Angeles, California. Interviews assessed individual, personal network, and substance use characteristics. Logistic regression examined individual and personal network predictors of the three most prevalent substances. Results In the past six months, the three most prevalent substances were marijuana (56%), crack (40%), and alcohol to intoxication (38%). The mental health status of homeless men was associated with substance use, with PTSD more common among those who used crack. Riskier networks (comprised of a larger proportion of drug users) were associated with marijuana use, and normative social ties (family, employed and school/work contacts) were associated with a decreased likelihood of crack use. Conclusions Mental health problems and riskier personal networks are associated with homeless men’s substance use. These findings underscore the importance of interventions that focus on improving mental health, mitigating the drug-using norms of personal networks, and helping men to maintain contact with normative, low-risk alters. Mental health care and peer-based, network interventions to reduce substance use should be a priority for heterosexually active homeless men. PMID:21601380

  10. China in the Schools: Directions and Priorities. Wingspread Conference.

    ERIC Educational Resources Information Center

    de Keijzer, Arne J.

    Results of a conference of educational leaders who were interested in teaching about China in secondary education are presented in this report. Points noted in the opening statement are the importance of cross-cultural understanding and the organization of China study in secondary education. The contents of a working paper, designed as a basis for…

  11. Local health department priority setting: an exploratory study.

    PubMed

    Platonova, Elena A; Studnicki, James; Fisher, John W; Bridger, Colleen

    2010-01-01

    Priority setting is an integral part of the community health assessment process since it helps direct the allocation of limited public health resources among competing needs. There is a recognized need for a systematic mechanism to prioritize community health issues in objective, data-driven, quantifiable measures. This exploratory study examined the extent to which data-driven objective criteria were considered important to public health officials in North Carolina and, specifically, the extent to which they chose between objective and subjective criteria in establishing public health priorities. The differences between the health officers' practice (criteria they actually used) and their preferences (criteria thought to be important) were also assessed. It was found that NC health directors generally used subjective criteria more often than objective criteria when deciding on the most important health issues in their communities. A considerable segment of the respondents, however, considered objective criteria more important, even though subjective criteria were the dominant influence in their actual practice of priority setting. Our preliminary results suggest that officers' education and tenure may influence their practice and preferences. Perceived and real barriers to the use of data-driven objective criteria for priority setting are an important topic for future public health research.

  12. 29 CFR 801.13 - Exemption of employers authorized to manufacture, distribute, or dispense controlled substances.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 801.35 of this part, to: (1) A prospective employee who would have direct access to the manufacture... have direct access or access to the controlled substances, as discussed below. (c) In order for a... “direct access” to the controlled substance(s) manufactured, dispensed, or distributed by the...

  13. 38 CFR 17.365 - Admission priorities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Admission priorities. 17.365 Section 17.365 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Grants to the Republic of the Philippines § 17.365 Admission priorities. Appropriate provisions of § 17...

  14. 38 CFR 17.365 - Admission priorities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Admission priorities. 17.365 Section 17.365 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Grants to the Republic of the Philippines § 17.365 Admission priorities. Appropriate provisions of § 17...

  15. 38 CFR 17.365 - Admission priorities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Admission priorities. 17.365 Section 17.365 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Grants to the Republic of the Philippines § 17.365 Admission priorities. Appropriate provisions of § 17...

  16. 38 CFR 17.365 - Admission priorities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Admission priorities. 17.365 Section 17.365 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Grants to the Republic of the Philippines § 17.365 Admission priorities. Appropriate provisions of § 17...

  17. 38 CFR 17.365 - Admission priorities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Admission priorities. 17.365 Section 17.365 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Grants to the Republic of the Philippines § 17.365 Admission priorities. Appropriate provisions of § 17...

  18. 32 CFR 644.315 - Disposal priorities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Disposal priorities. 644.315 Section 644.315 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal § 644.315 Disposal priorities. Consistent with the best interest of the United...

  19. Research Priorities in Networking and Communications.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    A workshop focused on major research issues in networking and communications. This report defines the context for research priorities and initiatives and deals with issues in networking and communications. Fifteen major research priorities and four research specific initiatives were identified by participants as areas that should be pursued over…

  20. 7 CFR 623.9 - Easement priority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Easement priority. 623.9 Section 623.9 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE WATER RESOURCES EMERGENCY WETLANDS RESERVE PROGRAM § 623.9 Easement priority. The State...

  1. Faculty Members' Instructional Priorities for Adopting OER

    ERIC Educational Resources Information Center

    Jung, Insung; Hong, Seongyoun

    2016-01-01

    This study aimed to investigate and classify faculty members' instructional priorities for adopting OER. In-depth interview data were collected from 10 faculty members from different regions and analyzed with NVivo 10. The original supposition was that the well-established instructional priorities, effectiveness, efficiency, and appeal would…

  2. Reframing Recreation as a Public Policy Priority

    ERIC Educational Resources Information Center

    Lovell, Phillip

    2011-01-01

    Issues pertaining to children often struggle to become public policy priorities. A clear demonstration of this phenomenon is the degree to which children are supported in the federal budget in comparison to other priorities. If issues pertaining to children struggle for the policy spotlight, subissues pertaining to them face an even greater…

  3. 7 CFR 4279.155 - Loan priorities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... applications on hand otherwise have equal priority, applications for loans from qualified veterans will have... necessary information related to determining the score, as requested. (1) Population priority. Projects located in an unincorporated area or in a city with under 25,000 population (10 points). (2) Community...

  4. Reframing Recreation as a Public Policy Priority

    ERIC Educational Resources Information Center

    Lovell, Phillip

    2011-01-01

    Issues pertaining to children often struggle to become public policy priorities. A clear demonstration of this phenomenon is the degree to which children are supported in the federal budget in comparison to other priorities. If issues pertaining to children struggle for the policy spotlight, subissues pertaining to them face an even greater…

  5. The Big Rocks: Priority Management for Principals

    ERIC Educational Resources Information Center

    Marshall, Kim

    2008-01-01

    How can a dedicated principal work really, really hard but fail to get significant gains in student achievement? The answer is obvious: by spending too much time on the wrong things and not enough on the right things. The principal's number-one priority is zeroing in on the highest-priority activities for bringing all students to high levels of…

  6. Learning Spaces as a Strategic Priority

    ERIC Educational Resources Information Center

    George, Gene; Erwin, Tom; Barnes, Briony

    2009-01-01

    In April 2007 Butler Community College made learning spaces one of its five strategic priorities. The college had just completed a major renovation of the work spaces for the IT division and had started a project to build a student union and create informal learning spaces at the Andover campus. With learning spaces becoming a strategic priority,…

  7. Learning Spaces as a Strategic Priority

    ERIC Educational Resources Information Center

    George, Gene; Erwin, Tom; Barnes, Briony

    2009-01-01

    In April 2007 Butler Community College made learning spaces one of its five strategic priorities. The college had just completed a major renovation of the work spaces for the IT division and had started a project to build a student union and create informal learning spaces at the Andover campus. With learning spaces becoming a strategic priority,…

  8. 40 CFR 35.2103 - Priority determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Priority determination. 35.2103 Section 35.2103 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works § 35.2103 Priority determination...

  9. 10 CFR 580.03 - Curtailment priorities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) CURTAILMENT PRIORITIES FOR ESSENTIAL AGRICULTURAL USES § 580.03 Curtailment priorities. (a) Notwithstanding any provision of law other than section 401(b) of the Natural Gas Policy Act of 1978, or any other rule, regulation, or order of...

  10. 10 CFR 580.03 - Curtailment priorities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) CURTAILMENT PRIORITIES FOR ESSENTIAL AGRICULTURAL USES § 580.03 Curtailment priorities. (a) Notwithstanding any provision of law other than section 401(b) of the Natural Gas Policy Act of 1978, or any other rule, regulation, or order of...

  11. 40 CFR 93.103 - Priority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DETERMINING... U.S.C. or the Federal Transit Laws § 93.103 Priority. When assisting or approving any action with air quality-related consequences, FHWA and FTA shall give priority to the implementation of...

  12. 40 CFR 93.103 - Priority.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DETERMINING... U.S.C. or the Federal Transit Laws § 93.103 Priority. When assisting or approving any action with air quality-related consequences, FHWA and FTA shall give priority to the implementation of...

  13. 48 CFR 8.704 - Purchase priorities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... priorities: (1) Supplies: (i) Federal Prison Industries, Inc. (41 U.S.C. 48). (ii) AbilityOne participating... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Purchase priorities. 8.704 Section 8.704 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING...

  14. 48 CFR 8.704 - Purchase priorities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... priorities: (1) Supplies: (i) Federal Prison Industries, Inc. (41 U.S.C. 48). (ii) AbilityOne participating... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Purchase priorities. 8.704 Section 8.704 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING...

  15. 48 CFR 8.704 - Purchase priorities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... priorities: (1) Supplies: (i) Federal Prison Industries, Inc. (41 U.S.C. 48). (ii) AbilityOne participating... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Purchase priorities. 8.704 Section 8.704 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING...

  16. Strategic Issues: Priorities for the Future.

    ERIC Educational Resources Information Center

    Alamo Community Coll. District, San Antonio, TX.

    Strategic priorities for the Alamo Community College District (ACCD) are identified based on conclusions drawn by the ACCD Community Advisory Council from studies of: (1) Bexar County population characteristics and trends; (2) community economic and social priorities; (3) college enrollment potential; (4) needs and characteristics of the ACCD's…

  17. The 50 Constellation Priority Sites

    NASA Technical Reports Server (NTRS)

    Noble, S.; Joosten, K.; Eppler, D.; Gruener, J.; Mendell, W.; French, R.; Plescia, J.; Spudis, P.; Wargo, M.; Robinson, M.; Lucey, P.

    2009-01-01

    The Constellation program (CxP) has developed a list of 50 sites of interest on the Moon which will be targeted by the LRO narrow angle camera. The list has also been provided to the M team to supplement their targeting list. This list does not represent a "site selection" process; rather the goal was to find "representative" sites and terrains to understand the range of possible surface conditions for human lunar exploration to aid engineering design and operational planning. The list compilers leveraged heavily on past site selection work (e.g. Geoscience and a Lunar Base Workshop - 1988, Site Selection Strategy for a Lunar Outpost - 1990, Exploration Systems Architecture Study (ESAS) - 2005). Considerations included scientific, resource utilization, and operational merits, and a desire to span lunar terrain types. The targets have been organized into two "tiers" of 25 sites each to provide a relative priority ranking in the event of mutual interference. A LEAG SAT (special action team) was established to validate and recommend modifications to the list. This SAT was chaired by Dr. Paul Lucey. They provided their final results to CxP in May. Dr. Wendell Mendell will organize an on-going analysis of the data as they come down to ensure data quality and determine if and when a site has sufficient data to be retired from the list. The list was compiled using the best available data, however, it is understood that with the flood of new lunar data, minor modifications or adjustments may be required.

  18. National priorities in marine pollution

    SciTech Connect

    Smith, W.M.; Leschine, T.M.; Landy, R.B.

    1988-02-01

    The National Ocean Pollution Program Office (NOPPO) of the National Oceanic and Atmospheric Administration is required by the National Ocean Pollution Planning Act (PL 95-273) to make recommendations on the federal program in marine pollution research, development, and monitoring, and promote interagency cooperation in these areas. The first step in evaluating the Federal effort in ocean pollution research is to identify the marine pollution needs and problems that are facing the nation. To broaden the knowledge base used in identifying and prioritizing these issues, NOPPO has consulted pollution experts outside as well as within the Federal Government using the Priorities Worksheet for National Marine Pollution Problems and Needs. The worksheet was mailed out in January 1987 to over 250 participants representing the following sectors of the ocean community: the Legislative and Executive Branches of the Federal Government, conservation groups, sport and commercial fisheries, offshore petroleum and mining interests, the ports and recreation industries, state and regional governments, and researchers in the marine pollution field. The list of participants was developed with the assistance of a steering committee.

  19. Research priorities: women in Africa.

    PubMed

    Okeyo, A P

    1979-01-01

    In December 1979, an Expert Meeting on Research and Data Collection on Women and Development was convened in Nairobi for the purpose of defining research priorities and methodological approaches for studying the role of African women in development. After reviewing current literature relevant to the subject matter, the participants developed a number of hypotheses regarding the impact of development activities on the role and status of women, and recommended that these hypotheses be tested in future reserach. In general, agrarian reform, mechanization of agriculture, the introduction of cash cropping, and modernization were hypothesized as having a negative impact on the role, status, productive activities, and nutritional standards of women. Other hypotheses stated that development programs and agricultural extension services tended to neglect women. Recommended research methodologies include: 1) efforts to involve the community members in the development and implementation of research projects undertaken in their communities; 2) increased use of local experts and community members in data collection; and 3) interdisciplinary collaboration. The participants also recommended that each country compile a statistical profile on the women in their countries. The profiles should include comparable information on: 1) fertility; 2) educational levels, employment status, and income levels for women; 3) household composition; and 4) types of services available to women.

  20. Research priorities in sarcomeric cardiomyopathies

    PubMed Central

    van der Velden, Jolanda; Ho, Carolyn Y.; Tardiff, Jil C.; Olivotto, Iacopo; Knollmann, Bjorn C.; Carrier, Lucie

    2015-01-01

    The clinical variability in patients with sarcomeric cardiomyopathies is striking: a mutation causes cardiomyopathy in one individual, while the identical mutation is harmless in a family member. Moreover, the clinical phenotype varies ranging from asymmetric hypertrophy to severe dilatation of the heart. Identification of a single phenotype-associated disease mechanism would facilitate the design of targeted treatments for patient groups with different clinical phenotypes. However, evidence from both the clinic and basic knowledge of functional and structural properties of the sarcomere argues against a ‘one size fits all’ therapy for treatment of one clinical phenotype. Meticulous clinical and basic studies are needed to unravel the initial and progressive changes initiated by sarcomere mutations to better understand why mutations in the same gene can lead to such opposing phenotypes. Ultimately, we need to design an ‘integrative physiology’ approach to fully realize patient/gene-tailored therapy. Expertise within different research fields (cardiology, genetics, cellular biology, physiology, and pharmacology) must be joined to link longitudinal clinical studies with mechanistic insights obtained from molecular and functional studies in novel cardiac muscle systems. New animal models, which reflect both initial and more advanced stages of sarcomeric cardiomyopathy, will also aid in achieving these goals. Here, we discuss current priorities in clinical and preclinical investigation aimed at increasing our understanding of pathophysiological mechanisms leading from mutation to disease. Such information will provide the basis to improve risk stratification and to develop therapies to prevent/rescue cardiac dysfunction and remodelling caused by sarcomere mutations. PMID:25631582

  1. Shaping priorities in genetic medicine.

    PubMed

    Boyle, Philip J

    1995-01-01

    ... Such moral problems raise the question whether society should make all or only some of the potential and existing genetic technologies widely available. Add to this the very real concern that the throng of products and services generated through this research has the potential to put significant further pressure on a health care system that already cannot provide adequate services to all persons. Given current restructuring of U.S. health services along the lines of managed health care, the need and desire of public and private parties to manage health resources aggressively by controlling costs and quality of care will call the question about what services to make available, to whom, on what basis. By what criteria should priorities be set? Should genetic services sought by only a few be made available? Should genetic screening and testing be offered for conditions for which there is no cure? Should specific groups be targeted for the distribution of genetic services? Are any genetic services more important than others? Where do genetic services fit relative to other health services? And -- the perennial question -- who should make these decisions? What does the newly emerging debate over the fair distribution of health resources mean for genetics?

  2. Direct and indirect exposure to air pollution.

    PubMed

    Thron, R W

    1996-02-01

    Hazardous substances that originally are discharged as air pollutants may find their pathway to human exposure through multiple routes, including ingestion and dermal contact, as well as direct inhalation. The mechanisms for modeling and understanding the fate of air pollutants through atmospheric transport, deposition into water and soil, bioaccumulation, and ultimate uptake to receptor organs and systems in the human body are complex. Pollution prevention programs can be better engineered, pollution priorities can be identified, and greater environmental public health gains (attributable to pollution prevention) can be achieved by evaluating the multiple pathways to human exposure and through improved dosage calculations. A single contaminant source often may represent only a fraction of a total body pollutant burden. Further research is needed on source culpability and attributable risk, long-range transport of air pollutants, human dose contributions by various pathways, better techniques for health risk assessment, and an identification of human behavior patterns that affect exposure and dose.

  3. [Priority setting for the health technology assessment].

    PubMed

    Poblete-Vargas, Sergio; Castillo-Laborde, Carla

    2014-01-01

    The aim of this article is to analyze the different approaches of priority setting for health technology assessments (HTA). First, the paper identifies the reasons that make necessary to establish priorities and its importance for the success of the HTA models. Second, it studies the main stages that consider the determination of priorities based on the analysis of the models currently used by HTA agencies of developed countries. In the third place, the article describes the different criteria, methods of scoring and deliberation bodies included in the mechanism of priority setting of those agencies. Finally, the paper concludes mentioning lessons from the international experience that potentially can be an input for the design of a model of priority setting for HTA in our country.

  4. Does physical abuse in early childhood predict substance use in adolescence and early adulthood?

    PubMed

    Lansford, Jennifer E; Dodge, Kenneth A; Pettit, Gregory S; Bates, John E

    2010-05-01

    Prospective longitudinal data from 585 families were used to examine parents' reports of child physical abuse in the first 5 years of life as a predictor of substance use at ages 12, 16, and 24. Path analyses revealed that physical abuse in the first 5 years of life predicted subsequent substance use for females but not males. We found a direct effect of early physical abuse on girls'substance use at age 12 and indirect effects on substance use at age 16 and age 24 through substance use at age 12. For boys, age 12 substance use predicted age 16 substance use, and age 16 substance use predicted age 24 substance use, but physical abuse in the first 5 years of life was unrelated to subsequent substance use. These findings suggest that for females, a mechanism of influence of early physical abuse on substance use into early adulthood appears to be through precocious initiation of substance use in early adolescence.

  5. Substance use during pregnancy and postnatal outcomes.

    PubMed

    Irner, Tina Birk; Teasdale, Thomas William; Nielsen, Tine; Vedal, Sissel; Olofsson, May

    2012-01-01

    Substance exposure in utero has been associated with physical birth defects and increased risk of regulatory and neuropsychological difficulties. The aims of this study were to describe women who use substances and are in treatment with respect to the type and number of substances used during pregnancy, as well as their background, and to examine the effect substance use has on gestational age, birth weight, and the development of neonatal abstinence syndrome at birth. A sample of 161 pregnant women and their 163 newborn children were included. The results indicate that the children whose mothers continued to use substances throughout their pregnancies were born at a lower gestational age (Chi-Square = 15.1(2), P < .01); children exposed to poly-substances in utero were more affected than those exposed to only alcohol and those with no substance exposure. The same children were more vulnerable to the development of neonatal abstinence syndrome at birth (Chi-Square = 51.7(2), P < .001). Newborns who were exposed primarily to alcohol in utero were at a significant risk of being born with low birth weight (Chi-Square = 8.8(2), P < .05) compared with those exposed to other types of substances. More than 50% of the mothers ceased using any substances (with the exception of tobacco) by birth, indicating that the treatment program did have an interventional effect on the mothers. The mothers' ability to either cease or decrease the use of substances during pregnancy appears to have direct positive effect on their newborns.

  6. Substance Abuse. Policy Statement.

    ERIC Educational Resources Information Center

    National Collaboration for Youth, Washington, DC.

    This paper presents the policy statement on substance abuse from the National Collaboration for Youth (NCY). The policy statement section lists programs and activities supported by the NCY. A section on background includes a statement of the issue of substance abuse. Areas examined in this section include alcohol abuse and drunk driving among…

  7. Special Issue: Substance Abuse.

    ERIC Educational Resources Information Center

    Fuhrmann, Barbara S., Ed.; Washington, Craig S., Ed.

    1984-01-01

    Presents ten articles about substance abuse: its effects, consequences, and strategies for intervention. Describes specific group therapy techniques and presents both a court service designed for assisting juveniles with drug/alcohol offenses, and a school-based substance abuse prevention program. Looks at strategies for counseling special…

  8. Substance Abuse Policy

    ERIC Educational Resources Information Center

    Cuzzolino, Robert

    This brochure outlines the substance abuse policy for students at the Philadelphia College of Osteopathic Medicine (PCOM/Pennsylvania). Noted are the dangers of substance abuse during the stressful time of medical training and later for the doctor and clients during professional practice. The policy's five goals are briefly stated. Described next…

  9. Substance Abuse and Disability.

    ERIC Educational Resources Information Center

    Sales, Amos

    A review of the literature provides the conclusion that individuals with a disability versus those without a disability are more likely to have a substance abuse problem and less likely to get effective treatment. Data suggest 10-40% of all individuals in treatment for substance abuse have a coexisting physical or mental disability. Alcohol rates…

  10. What are your priorities right now? Identifying service needs across recovery stages to inform service development.

    PubMed

    Laudet, Alexandre B; White, William

    2010-01-01

    Substance use disorders (SUD) are, for many, chronic conditions that are typically associated with severe impairments in multiple areas of functioning. "Recovery" from SUD is, for most, a lengthy process; improvements in other areas of functioning do not necessarily follow the attainment of abstinence. The current SUD service model providing intense, short-term, symptom-focused services is ill-suited to address these issues. A recovery-oriented model of care is emerging, which provides coordinated recovery-support services using a chronic-care model of sustained recovery management. Information is needed about substance users' priorities, particularly persons in recovery who are not currently enrolled in treatment, to guide the development of recovery-oriented systems. As a first step in filling this gap, we present qualitative data on current life priorities among a sample of individuals that collectively represent successive recovery stages (N = 356). Findings suggest that many areas of functioning remain challenging long after abstinence is attained, most notably employment and education, family/social relations, and housing. Although the ranking of priorities changes somewhat across recovery stages, employment is consistently the second most important priority, behind working on one's recovery. Study limitations are noted, and the implications of findings for the development and evaluation of recovery-oriented services are discussed.

  11. Research priorities in sarcomeric cardiomyopathies.

    PubMed

    van der Velden, Jolanda; Ho, Carolyn Y; Tardiff, Jil C; Olivotto, Iacopo; Knollmann, Bjorn C; Carrier, Lucie

    2015-04-01

    The clinical variability in patients with sarcomeric cardiomyopathies is striking: a mutation causes cardiomyopathy in one individual, while the identical mutation is harmless in a family member. Moreover, the clinical phenotype varies ranging from asymmetric hypertrophy to severe dilatation of the heart. Identification of a single phenotype-associated disease mechanism would facilitate the design of targeted treatments for patient groups with different clinical phenotypes. However, evidence from both the clinic and basic knowledge of functional and structural properties of the sarcomere argues against a 'one size fits all' therapy for treatment of one clinical phenotype. Meticulous clinical and basic studies are needed to unravel the initial and progressive changes initiated by sarcomere mutations to better understand why mutations in the same gene can lead to such opposing phenotypes. Ultimately, we need to design an 'integrative physiology' approach to fully realize patient/gene-tailored therapy. Expertise within different research fields (cardiology, genetics, cellular biology, physiology, and pharmacology) must be joined to link longitudinal clinical studies with mechanistic insights obtained from molecular and functional studies in novel cardiac muscle systems. New animal models, which reflect both initial and more advanced stages of sarcomeric cardiomyopathy, will also aid in achieving these goals. Here, we discuss current priorities in clinical and preclinical investigation aimed at increasing our understanding of pathophysiological mechanisms leading from mutation to disease. Such information will provide the basis to improve risk stratification and to develop therapies to prevent/rescue cardiac dysfunction and remodelling caused by sarcomere mutations. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com.

  12. Priorities for CMV vaccine development.

    PubMed

    Krause, Philip R; Bialek, Stephanie R; Boppana, Suresh B; Griffiths, Paul D; Laughlin, Catherine A; Ljungman, Per; Mocarski, Edward S; Pass, Robert F; Read, Jennifer S; Schleiss, Mark R; Plotkin, Stanley A

    2013-12-17

    A multidisciplinary meeting addressed priorities related to development of vaccines against cytomegalovirus (CMV), the cause of congenital CMV (cCMV) disease and of serious disease in the immunocompromised. Participants discussed optimal uses of a CMV vaccine, aspects of clinical study design, and the value of additional research. A universal childhood CMV vaccine could potentially rapidly reduce cCMV disease, as infected children are sources of viral transmission to seronegative and seropositive mothers. A vaccine administered to adolescents or adult women could also reduce cCMV disease by making them immune prior to pregnancy. Clinical trials of CMV vaccines in women should evaluate protection against cCMV infection, an essential precursor of cCMV disease, which is a more practical and acceptable endpoint for assessing vaccine effects on maternal-fetal transmission. Clinical trials of vaccines to evaluate prevention of CMV disease in stem cell transplant recipients could use CMV viremia at a level triggering pre-emptive antiviral therapy as an endpoint, because widespread use of pre-emptive and prophylactic antivirals has rendered CMV-induced disease too rare to be a practical endpoint for clinical trials. In solid organ transplant patients, CMV-associated disease is sufficiently common for use as a primary endpoint. Additional research to advance CMV vaccine development should include identifying factors that predict fetal loss due to CMV, determining age-specific incidence and transmission rates, defining the mechanism and relative contributions of maternal reactivation and re-infection to cCMV disease, developing assays that can distinguish between reactivation and re-infection in seropositive vaccinees, further defining predictors of sequelae from cCMV infection, and identifying clinically relevant immune response parameters to CMV (including developing validated assays that could assess CMV antibody avidity) that could lead to the establishment of immune

  13. Health assessment for Burlington Northern Railroad Brainerd National Priorities List (NPL) Site, Brainerd, Minnesota, Region 5. CERCLIS No. MND000686196. Final report

    SciTech Connect

    Not Available

    1988-12-08

    The Burlington Northern Railroad Brainerd National Priorities List Site is located outside Brainerd, Minnesota. Railroad ties have been preserved with creosote mixtures at the facility since 1907. Waste water generated from this activity was discharged resulting in the accumulation of sludge in the impoundments. Polynuclear aromatic hydrocarbons (PAHs) in the sludge have migrated and contaminated the underlying soil and ground water. The ground water contamination has not migrated appreciably or entered any potable water supply wells. The site, however, is of potential public health concern because of the risk to human health resulting from possible exposure to hazardous substances at concentrations that may result in adverse health effects. Human exposure to PAHs may have occurred and may be occurring on-site via inhalation, ingestion, and direct dermal contact with contaminated soil, sludge, and groundwater.

  14. Health assessment for Beacon Heights Landfill National Priorities List (NPL) Site, Beacon Falls, Connecticut, Region 1. CERCLIS No. CTD001145671. Final report

    SciTech Connect

    Not Available

    1989-01-26

    The Beacon Heights Landfill National Priorities List (NPL) Site is located in Beacon Falls, Connecticut. From the 1920's to 1979, municipal and industrial wastes were disposed of at the landfill. Leachate from the landfill has migrated into the local groundwater aquifers. Two residential wells to the northwest of the site have been contaminated with site-related contaminants. This site is of potential public health concern because of the risk to human health resulting from possible exposure to hazardous substances at concentrations that may result in adverse health effects. Human exposure to benzene, chlorobenzene, chloroethane, and methylene chloride may have occurred via ingestion, inhalation, and direct dermal contact with contaminated groundwater. No health study follow-up is indicated at this time.

  15. Health assessment for Burrows Sanitation Landfill National Priorities List (NPL) Site, Hartford, Van Buren County, Michigan, Region 5. CERCLIS No. MID980410617. Final report

    SciTech Connect

    Not Available

    1988-07-29

    The Burrows Sanitation Landfill is a National Priorities List site located in a rural area approximately one mile northeast of the City of Hartford, Van Buren County, Michigan. The contaminants found at the site consist of chromium, lead, and nickel in the ground water, surface soils, surface waters, and sediments. There are three residences within 300 feet of the site boundary. The site is of potential public health concern because of the risk to human health that could result from possible exposure to hazardous substances at levels that may result in adverse health effects over time. Human exposure to nickel and chromium may be occurring via ingestion of and direct contact with surface soils. However, proposed remediation measures should adequately prevent future exposure to these contaminants.

  16. Consumer design priorities for upper limb prosthetics.

    PubMed

    Biddiss, Elaine; Beaton, Dorcas; Chau, Tom

    2007-11-01

    To measure consumer satisfaction with upper limb prosthetics and provide an enumerated list of design priorities for future developments. A self-administered, anonymous survey collected information on participant demographics, history of and goals for prosthesis use, satisfaction, and design priorities. The questionnaire was available online and in paper format and was distributed through healthcare providers, community support groups, and one prosthesis manufacturer; 242 participants of all ages and levels of upper limb absence completed the survey. Rates of rejection for myoelectric hands, passive hands, and body-powered hooks were 39%, 53%, and 50%, respectively. Prosthesis wearers were generally satisfied with their devices while prosthesis rejecters were dissatisfied. Reduced prosthesis weight emerged as the highest priority design concern of consumers. Lower cost ranked within the top five design priorities for adult wearers of all device types. Life-like appearance is a priority for passive/cosmetic prostheses, while improved harness comfort, wrist movement, grip control and strength are required for body-powered devices. Glove durability, lack of sensory feedback, and poor dexterity were also identified as design priorities for electric devices. Design priorities reflect consumer goals for prosthesis use and vary depending on the type of prosthesis used and age. Future design efforts should focus on the development of more light-weight, comfortable prostheses.

  17. Setting research priorities for Type 1 diabetes.

    PubMed

    Gadsby, R; Snow, R; Daly, A C; Crowe, S; Matyka, K; Hall, B; Petrie, J

    2012-10-01

    Research priorities are often set by academic researchers or the pharmaceutical industry. The interests of patients, carers and clinicians may therefore be overlooked and research questions that matter may be neglected. The aims of this study were to collect uncertainties about the treatment of Type 1 diabetes from patients, carers and health professionals, and to collate and prioritize these uncertainties to develop a top 10 list of research priorities, using a structured priority-setting partnership of patients, carers, health professionals and diabetes organizations, as described by the James Lind Alliance. A partnership of interested organizations was set up, and from this a steering committee of 10 individuals was formed. An online and paper survey was used to identify uncertainties. These were collated, and the steering group carried out an interim priority-setting exercise with partner organizations. This group of uncertainties was then voted on to give a smaller list that went forward to the final priority-setting workshop. At this meeting, a final list of the top 10 research priorities was agreed. An initial 1141 uncertainties were described. These were reduced to 88 indicative questions, 47 of which went out for voting. Twenty-four were then taken forward to a final priority-setting workshop. This workshop resulted in a list of top 10 research priorities in Type 1 diabetes. We have shown that it is possible using the James Lind Alliance process to develop an agreed top 10 list of research priorities for Type 1 diabetes from health professionals, patients and carers. © 2012 The Authors. Diabetic Medicine © 2012 Diabetes UK.

  18. 7 CFR 1466.4 - National priorities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... sedimentation from unacceptable levels on agricultural land; and (5) Promotion of at-risk species habitat... and local priorities to assist with prioritization and selection of EQIP applications, and...

  19. 7 CFR 1466.4 - National priorities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... sedimentation from unacceptable levels on agricultural land; and (5) Promotion of at-risk species habitat... and local priorities to assist with prioritization and selection of EQIP applications, and...

  20. Competing priorities: staff perspectives on supporting recovery.

    PubMed

    Le Boutillier, Clair; Slade, Mike; Lawrence, Vanessa; Bird, Victoria J; Chandler, Ruth; Farkas, Marianne; Harding, Courtenay; Larsen, John; Oades, Lindsay G; Roberts, Glenn; Shepherd, Geoff; Thornicroft, Graham; Williams, Julie; Leamy, Mary

    2015-07-01

    Recovery has come to mean living a life beyond mental illness, and recovery orientation is policy in many countries. The aims of this study were to investigate what staff say they do to support recovery and to identify what they perceive as barriers and facilitators associated with providing recovery-oriented support. Data collection included ten focus groups with multidisciplinary clinicians (n = 34) and team leaders (n = 31), and individual interviews with clinicians (n = 18), team leaders (n = 6) and senior managers (n = 8). The identified core category was Competing Priorities, with staff identifying conflicting system priorities that influence how recovery-oriented practice is implemented. Three sub-categories were: Health Process Priorities, Business Priorities, and Staff Role Perception. Efforts to transform services towards a recovery orientation require a whole-systems approach.

  1. NASA-GSFC Orbital Debris Research Priorities

    NASA Technical Reports Server (NTRS)

    Hull, Scott M.

    2014-01-01

    While quite a lot is known about the orbital debris environment and how to limit its growth, more remains to be learned. The curent priorities for research and development, from the NASA Goddard Space Flight Center perspective, will be discussed.

  2. 48 CFR 873.103 - Priority sources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... resources consisting of commercial services or the use of medical equipment or space. (38 U.S.C. 8153) ... SUPPLEMENTARY REGULATIONS SIMPLIFIED ACQUISITION PROCEDURES FOR HEALTH-CARE RESOURCES 873.103 Priority sources...

  3. 42 CFR 57.1506 - Priority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING... to Assist in Construction of Teaching Facilities for Health Profession Personnel § 57.1506 Priority... will begin its teaching program....

  4. 42 CFR 57.1506 - Priority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING... to Assist in Construction of Teaching Facilities for Health Profession Personnel § 57.1506 Priority... will begin its teaching program....

  5. 42 CFR 57.1506 - Priority.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING... to Assist in Construction of Teaching Facilities for Health Profession Personnel § 57.1506 Priority... will begin its teaching program....

  6. 42 CFR 57.1506 - Priority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING... to Assist in Construction of Teaching Facilities for Health Profession Personnel § 57.1506 Priority... will begin its teaching program....

  7. 42 CFR 57.1506 - Priority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING... to Assist in Construction of Teaching Facilities for Health Profession Personnel § 57.1506 Priority... will begin its teaching program....

  8. Substance use during pregnancy

    PubMed Central

    Forray, Ariadna

    2016-01-01

    Prenatal substance use is a critical public health concern that is linked with several harmful maternal and fetal consequences. The most frequently used substance in pregnancy is tobacco, followed by alcohol, cannabis and other illicit substances. Unfortunately, polysubstance use in pregnancy is common, as well as psychiatric comorbidity, environmental stressors, and limited and disrupted parental care, all of which can compound deleterious maternal and fetal outcomes. There are few existing treatments for prenatal substance use and these mainly comprise behavioral and psychosocial interventions. Contingency management has been shown to be the most efficacious of these. The purpose of this review is to examine the recent literature on the prenatal use of tobacco, alcohol, cannabis, stimulants, and opioids, including the effects of these on maternal and fetal health and the current therapeutic options. PMID:27239283

  9. Substance use - LSD

    MedlinePlus

    Substance abuse - LSD; Drug abuse - LSD; Drug use - LSD; Lysergic acid diethylamide; Hallucinogen - LSD ... PA: Elsevier; 2016:chap 50. National Institute on Drug Abuse. Research report series: Hallucinogens and dissociative drugs. Updated ...

  10. Toxic substances alert program

    NASA Technical Reports Server (NTRS)

    Junod, T. L.

    1978-01-01

    A toxicity profile is provided, of 187 toxic substances procured by NASA Lewis Research Center during a 3 1/2 year period, including 27 known or suspected carcinogens. The goal of the program is to assure that the center's health and safety personnel are aware of the procurement and use of toxic substances and to alert and inform the users of these materials as to the toxic characteristics and the control measures needed to ensure their safe use. The program also provides a continuing record of the toxic substances procured, who procured them, what other toxic substances the user has obtained in the past, and where similar materials have been used elsewhere at the center.

  11. Toxic substances handbook

    NASA Technical Reports Server (NTRS)

    Junod, T. L.

    1979-01-01

    Handbook, published in conjunction with Toxic Substances Alert Program at NASA Lewis Research Center, profiles 187 toxic chemicals in their relatively pure states and include 27 known or suspected carcinogens.

  12. Substance use during pregnancy.

    PubMed

    Forray, Ariadna

    2016-01-01

    Prenatal substance use is a critical public health concern that is linked with several harmful maternal and fetal consequences. The most frequently used substance in pregnancy is tobacco, followed by alcohol, cannabis and other illicit substances. Unfortunately, polysubstance use in pregnancy is common, as well as psychiatric comorbidity, environmental stressors, and limited and disrupted parental care, all of which can compound deleterious maternal and fetal outcomes. There are few existing treatments for prenatal substance use and these mainly comprise behavioral and psychosocial interventions. Contingency management has been shown to be the most efficacious of these. The purpose of this review is to examine the recent literature on the prenatal use of tobacco, alcohol, cannabis, stimulants, and opioids, including the effects of these on maternal and fetal health and the current therapeutic options.

  13. Toxic substances handbook

    NASA Technical Reports Server (NTRS)

    Junod, T. L.

    1979-01-01

    Handbook, published in conjunction with Toxic Substances Alert Program at NASA Lewis Research Center, profiles 187 toxic chemicals in their relatively pure states and include 27 known or suspected carcinogens.

  14. Supervision: Substance and Style

    ERIC Educational Resources Information Center

    Gellerman, Saul W.

    1976-01-01

    Argues that managerial style and substance are inextricably intertwined, illustrating the discussion with excerpts from an extensive study and job analysis of first-line supervisors in a food packaging plant. (JG)

  15. Substance use - marijuana

    MedlinePlus

    Substance abuse - marijuana; Drug abuse - marijuana; Drug use - marijuana; Cannabis; Grass; Hashish; Mary Jane; Pot; Weed ... several minutes. If you eat foods containing the drug as an ingredient, such as brownies, you may ...

  16. Schizophrenia and substance abuse.

    PubMed

    Smith, J; Hucker, S

    1994-07-01

    Recent research from North America has demonstrated higher than expected rates of drug and alcohol abuse among the seriously mentally ill. Schizophrenics appear to be particularly susceptible to the negative effects of substance abuse. These include psychiatric and social complications, with antisocial behaviour, particularly violence emerging as one of the most worrying features. This review examines the strength of the association and explores the possible explanations for the apparent link between schizophrenia, substance abuse and violence. The literature was searched using Medline, supplemented with a manual literature search. Very few articles specifically approached the problem of violence among substance abusing schizophrenics, but over 80 papers were identified which were helpful in exploring the link between dangerous behaviour and substance abuse by schizophrenics. While there is circumstantial evidence to support the hypothesis that schizophrenics who abuse drugs or alcohol are at an increased risk of behaving violently, longitudinal studies are required to facilitate a better understanding of the mediating mechanisms.

  17. Establishing research priorities for patient safety in emergency medicine: a multidisciplinary consensus panel.

    PubMed

    Plint, Amy C; Stang, Antonia S; Calder, Lisa A

    2015-01-01

    Patient safety in the context of emergency medicine is a relatively new field of study. To date, no broad research agenda for patient safety in emergency medicine has been established. The objective of this study was to establish patient safety-related research priorities for emergency medicine. These priorities would provide a foundation for high-quality research, important direction to both researchers and health-care funders, and an essential step in improving health-care safety and patient outcomes in the high-risk emergency department (ED) setting. A four-phase consensus procedure with a multidisciplinary expert panel was organized to identify, assess, and agree on research priorities for patient safety in emergency medicine. The 19-member panel consisted of clinicians, administrators, and researchers from adult and pediatric emergency medicine, patient safety, pharmacy, and mental health; as well as representatives from patient safety organizations. In phase 1, we developed an initial list of potential research priorities by electronically surveying a purposeful and convenience sample of patient safety experts, ED clinicians, administrators, and researchers from across North America using contact lists from multiple organizations. We used simple content analysis to remove duplication and categorize the research priorities identified by survey respondents. Our expert panel reached consensus on a final list of research priorities through an in-person meeting (phase 3) and two rounds of a modified Delphi process (phases 2 and 4). After phases 1 and 2, 66 unique research priorities were identified for expert panel review. At the end of phase 4, consensus was reached for 15 research priorities. These priorities represent four themes: (1) methods to identify patient safety issues (five priorities), (2) understanding human and environmental factors related to patient safety (four priorities), (3) the patient perspective (one priority), and (4) interventions for

  18. Organic substances in water

    USGS Publications Warehouse

    Greeson, Phillip E.

    1981-01-01

    This is the third of several compilations of briefing papers on water quality by the U.S. Geological Survey. Each briefing paper is prepared in a simple, nontechnical, easy-to-understand manner. This U.S. Geological Survey Circular contains papers on selected organic substances in water. Briefing papers are included on ' Why study organic substances in water. ', ' Taste and odor in water ', and ' Classification and fractionation of organic solutes in natural waters'. (USGS)

  19. Playing video games while using or feeling the effects of substances: associations with substance use problems.

    PubMed

    Ream, Geoffrey L; Elliott, Luther C; Dunlap, Eloise

    2011-10-01

    This study tested the hypothesis that playing video games while using or feeling the effects of a substance--referred to herein as "concurrent use"-is related to substance use problems after controlling for substance use frequency, video gaming as an enthusiastic hobby, and demographic factors. Data were drawn from a nationally representative online survey of adult video gamers conducted by Knowledge Networks, valid n = 2,885. Problem video game playing behavior was operationalized using Tejeiro Salguero and Bersabé Morán's 2002 problem video game play (PVP) measure, and measures for substance use problems were taken from the National Survey of Drug Use and Health (NSDUH). Separate structural equation modeling analyses were conducted for users of caffeine, tobacco, alcohol, and marijuana. In all four models, concurrent use was directly associated with substance use problems, but not with PVP. Video gaming as an enthusiastic hobby was associated with substance use problems via two indirect paths: through PVP for all substances, and through concurrent use for caffeine, tobacco, and alcohol only. Results illustrate the potential for "drug interaction" between self-reinforcing behaviors and addictive substances, with implications for the development of problem use.

  20. Priority wetland invertebrates as conservation surrogates.

    PubMed

    Ormerod, S J; Durance, Isabelle; Terrier, Aurelie; Swanson, Alisa M

    2010-04-01

    Invertebrates are important functionally in most ecosystems, but seldom appraised as surrogate indicators of biological diversity. Priority species might be good candidates; thus, here we evaluated whether three freshwater invertebrates listed in the U.K. Biodiversity Action Plan indicated the richness, composition, and conservation importance of associated wetland organisms as defined respectively by their alpha diversity, beta diversity, and threat status. Sites occupied by each of the gastropods Segmentina nitida, Anisus vorticulus, and Valvata macrostoma had greater species richness of gastropods and greater conservation importance than other sites. Each also characterized species assemblages associated with significant variations between locations in alpha or beta diversity among other mollusks and aquatic macrophytes. Because of their distinct resource requirements, conserving the three priority species extended the range of wetland types under management for nature conservation by 18% and the associated gastropod niche-space by around 33%. Although nonpriority species indicated variations in richness, composition, and conservation importance among other organisms as effectively as priority species, none characterized such a wide range of high-quality wetland types. We conclude that priority invertebrates are no more effective than nonpriority species as indicators of alpha and beta diversity or conservation importance among associated organisms. Nevertheless, conserving priority species can extend the array of distinct environments that are protected for their specialized biodiversity and environmental quality. We suggest that this is a key role for priority species and conservation surrogates more generally, and, on our evidence, can best be delivered through multiple species with contrasting habitat requirements.

  1. Research priorities for zoonoses and marginalized infections.

    PubMed

    2012-01-01

    This report provides a review and analysis of the research landscape for zoonoses and marginalized infections which affect poor populations, and a list of research priorities to support disease control. The work is the output of the Disease Reference Group on Zoonoses and Marginalized Infectious Diseases of Poverty (DRG6), which is part of an independent think tank of international experts, established and funded by the Special Programme for Research and Training in Tropical Diseases (TDR), to identify key research priorities through review of research evidence and input from stakeholder consultations. The report covers a diverse range of diseases, including zoonotic helminth, protozoan, viral and bacterial infections considered to be neglected and associated with poverty. Disease-specific research issues are elaborated under individual disease sections and many common priorities are identified among the diseases such as the need for new and/or improved drugs and regimens, diagnostics and, where appropriate, vaccines. The disease-specific priorities are described as micro priorities compared with the macro level priorities which will drive policy-making for: improved surveillance; interaction between the health, livestock, agriculture, natural resources and wildlife sectors in tackling zoonotic diseases; and true assessment of the burden of zoonoses. This is one often disease and thematic reference group reports that have come out of the TDR Think Tank, all of which have contributed to the development of the Global Report search on Infectious Diseases of Poverty, available at: w.who.int/tdr/stewardship/global_report/en/index.html.

  2. Exposure to Violence, Substance Use, and Neighborhood Context

    PubMed Central

    Wright, Emily M.; Pinchevsky, Gillian M.

    2014-01-01

    Adolescent exposure to violence and substance use are both public health problems, but how neighborhood context contributes to these outcomes is unclear. This study uses prospective data from 1,416 adolescents to examine the direct and interacting influences of victimization and neighborhood factors on adolescent substance use. Based on hierarchical Bernoulli regression models that controlled for prior substance use and multiple individual-level factors, exposure to violence significantly increased the likelihood of marijuana use but not alcohol use or binge drinking. There was little evidence that community norms regarding adolescent substance use influenced rates of substance use or moderated the impact of victimization. Community disadvantage did not directly impact substance use, but the relationship between victimization and marijuana use was stronger for those in neighborhoods with greater disadvantage. The results suggest that victimization is particularly likely to affect adolescents’ marijuana use, and that this relationship may be contingent upon neighborhood economic conditions. PMID:25432621

  3. Exposure to violence, substance use, and neighborhood context.

    PubMed

    Fagan, Abigail A; Wright, Emily M; Pinchevsky, Gillian M

    2015-01-01

    Adolescent exposure to violence and substance use are both public health problems, but how neighborhood context contributes to these outcomes is unclear. This study uses prospective data from 1416 adolescents to examine the direct and interacting influences of victimization and neighborhood factors on adolescent substance use. Based on hierarchical Bernoulli regression models that controlled for prior substance use and multiple individual-level factors, exposure to violence significantly increased the likelihood of marijuana use but not alcohol use or binge drinking. There was little evidence that community norms regarding adolescent substance use influenced rates of substance use or moderated the impact of victimization. Community disadvantage did not directly impact substance use, but the relationship between victimization and marijuana use was stronger for those in neighborhoods with greater disadvantage. The results suggest that victimization is particularly likely to affect adolescents' marijuana use, and that this relationship may be contingent upon neighborhood economic conditions.

  4. Final Priority; Rehabilitation Training: Vocational Rehabilitation Technical Assistance Center--Youth With Disabilities. Final priority.

    PubMed

    2015-07-30

    The Assistant Secretary for Special Education and Rehabilitative Services announces a priority under the Rehabilitation Training program. The Assistant Secretary may use this priority for competitions in fiscal year (FY) 2015 and later years. This priority is designed to ensure that professionals working in State vocational rehabilitation (VR) agencies receive the technical assistance (TA) they need to provide youth with disabilities with services and supports that lead to postsecondary education and competitive integrated employment.

  5. Illicit substance use in pregnancy – a review

    PubMed Central

    Scott, Katherine; Lust, Karin

    2010-01-01

    Illicit substance use is not uncommon in women of childbearing age. The direct effects of illicit substance use on the mother, pregnancy and the fetus are not well understood, in contrast to the indirect effects of social disadvantage and intercurrent medical and psychiatric illness, which are well documented. We have undertaken a review of the current literature regarding the effects of illicit substance use in pregnancy and include a suggested approach to identification and management of at-risk women. PMID:27579069

  6. Community-Based Decision Making and Priority Setting Using the R Software: The Community Priority Index

    PubMed Central

    Salihu, Hamisu M.; Salinas-Miranda, Abraham A.; Paothong, Arnut; Wang, Wei; King, Lindsey M.

    2015-01-01

    This paper outlines how to compute community priority indices in the context of multicriteria decision making in community settings. A simple R function was developed and validated with community needs assessment data. Particularly, the first part of this paper briefly overviews the existing methods for priority setting and reviews the utility of a multicriteria decision-making approach for community-based prioritization. The second part illustrates how community priority indices can be calculated using the freely available R program to handle community data by showing the computational and mathematical steps of CPI (Community Priority Index) with bootstrapped 95% confidence intervals. PMID:25815045

  7. 77 FR 65002 - Best Pharmaceuticals for Children Act (BPCA) Priority List of Needs in Pediatric Therapeutics

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... Priorities and Diseases with Limited Alternative Therapies Table 13: Dermatologic Disease Priorities Table 14... Table 5: Bio-defense Research Priorities Table 6: Pediatric Cancer Priorities Table 7:...

  8. Prevalence of Substance Use in Patients Diagnosed with Schizophrenia

    PubMed Central

    TEKİN ULUDAĞ, Yasemin; GÜLEÇ, Gülcan

    2016-01-01

    Introduction Substance abuse among schizophrenic patients is a growing clinical concern. Substance use disorders and their effects on the course of schizophrenia have made the identification and treatment of schizophrenic patients a high priority. This study aimed to investigate the prevalence of substance use, preferred types of substances, sociodemographic characteristics and clinical features of schizophrenia, and substance use impact in schizophrenic patients. Methods Hundred patients who were consecutively admitted to the psychiatry clinic and were diagnosed with schizophrenia according to the DSM-IV criteria were enrolled in this study. Individual interviews were conducted during the patients. In order to evaluate substance abuse disorder (SAD) as per DSM-IV criteria, the substance use disorder section of the structured clinical interview for DSM disorders-II (SCID-II) form was used. In addition, the following were applied to schizophren-ic patients: sociodemographic data form, medical history form, Brief Disability Questionnaire (BDQ), UKU Side Effect Rating Scale (UKUSERS), Insight Rating Scale (IRS), Alcohol Use Dis-orders Identification Test (AUDIT), Fagerstrom Nicotine Dependence Test (FNDT), Global As-sessment of Functioning Scale (GAF), Scale for the Assessment of Positive Symptoms (SAPS), Scale for the Assessment of Negative Symptoms (SANS), and Calgary Depression Scale (CDS). Results Schizophrenia and alcohol and drug use were more common in males, and younger age was found to have no association with substance use. Unemployment, low education levels, rural survival rates, age at disease onset, the doctor first age of the applicant, the first inpatient years, legal issues, harm caused by others and suicidal behavior, SAPS, SANS, CDS received from their scores significant difference was detected. Schizophrenic patients with substance use had higher side effects of drugs, disability, and psychopathology scores than schizophrenic patients without

  9. Identification of priority organic compounds in groundwater recharge of China.

    PubMed

    Li, Zhen; Li, Miao; Liu, Xiang; Ma, Yeping; Wu, Miaomiao

    2014-09-15

    Groundwater recharge using reclaimed water is considered a promising method to alleviate groundwater depletion, especially in arid areas. Traditional water treatment systems are inefficient to remove all the types of contaminants that would pose risks to groundwater, so it is crucial to establish a priority list of organic compounds (OCs) that deserve the preferential treatment. In this study, a comprehensive ranking system was developed to determine the list and then applied to China. 151 OCs, for which occurrence data in the wastewater treatment plants were available, were selected as candidate OCs. Based on their occurrence, exposure potential and ecological effects, two different rankings of OCs were established respectively for groundwater recharge by surface infiltration and direct aquifer injection. Thirty-four OCs were regarded as having no risks while the remaining 117 OCs were divided into three groups: high, moderate and low priority OCs. Regardless of the recharge way, nonylphenol, erythromycin and ibuprofen were the highest priority OCs; their removal should be prioritized. Also the database should be updated as detecting technology is developed. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Federal priorities and programs in the hydrological sciences

    NASA Astrophysics Data System (ADS)

    Hartmann, H. C.; Thiemann, M.; Rentas, C.; Meixner, T.; Goodwin, K.; Boyle, D.; Sorooshian, S.

    How high a priority is hydrologic research for U.S. federal agencies? Although hydrology affects human lives and economic activity significantly, federal agency research priorities ultimately reflect the ability of the research community to generate political support, both locally and nationally. Unless the research community cultivates a vocal constituency by demonstrating the practical benefits of hydrologic research products, we risk declining federal support as other scientific disciplines step forward to direct federal agency priorities. Also, several hydrology programs require immediate mobilization of support to prevent losses in research capabilities. These were the conclusions of panel members participating in a uniquely frank “Town Hall Meeting” of the Hydrology Section at the 1998 AGU Fall Meeting. Agency representatives attending included Ghassem R. Asrar, NASA Associate Administrator for Earth Science; D.James Baker, NOAA Administrator; Robert M. Hirsch, Director of the USGS Water Resources Division; and George M. Hornberger, Chair of the National Research Council (NRC) Commission on Geosciences, Environment, and Resources (CGER).

  11. Global Conservation Priorities for Marine Turtles

    PubMed Central

    Wallace, Bryan P.; DiMatteo, Andrew D.; Bolten, Alan B.; Chaloupka, Milani Y.; Hutchinson, Brian J.; Abreu-Grobois, F. Alberto; Mortimer, Jeanne A.; Seminoff, Jeffrey A.; Amorocho, Diego; Bjorndal, Karen A.; Bourjea, Jérôme; Bowen, Brian W.; Briseño Dueñas, Raquel; Casale, Paolo; Choudhury, B. C.; Costa, Alice; Dutton, Peter H.; Fallabrino, Alejandro; Finkbeiner, Elena M.; Girard, Alexandre; Girondot, Marc; Hamann, Mark; Hurley, Brendan J.; López-Mendilaharsu, Milagros; Marcovaldi, Maria Angela; Musick, John A.; Nel, Ronel; Pilcher, Nicolas J.; Troëng, Sebastian; Witherington, Blair; Mast, Roderic B.

    2011-01-01

    Where conservation resources are limited and conservation targets are diverse, robust yet flexible priority-setting frameworks are vital. Priority-setting is especially important for geographically widespread species with distinct populations subject to multiple threats that operate on different spatial and temporal scales. Marine turtles are widely distributed and exhibit intra-specific variations in population sizes and trends, as well as reproduction and morphology. However, current global extinction risk assessment frameworks do not assess conservation status of spatially and biologically distinct marine turtle Regional Management Units (RMUs), and thus do not capture variations in population trends, impacts of threats, or necessary conservation actions across individual populations. To address this issue, we developed a new assessment framework that allowed us to evaluate, compare and organize marine turtle RMUs according to status and threats criteria. Because conservation priorities can vary widely (i.e. from avoiding imminent extinction to maintaining long-term monitoring efforts) we developed a “conservation priorities portfolio” system using categories of paired risk and threats scores for all RMUs (n = 58). We performed these assessments and rankings globally, by species, by ocean basin, and by recognized geopolitical bodies to identify patterns in risk, threats, and data gaps at different scales. This process resulted in characterization of risk and threats to all marine turtle RMUs, including identification of the world's 11 most endangered marine turtle RMUs based on highest risk and threats scores. This system also highlighted important gaps in available information that is crucial for accurate conservation assessments. Overall, this priority-setting framework can provide guidance for research and conservation priorities at multiple relevant scales, and should serve as a model for conservation status assessments and priority-setting for

  12. Substance use capital: Social resources enhancing youth substance use.

    PubMed

    Baggio, S; Mohler-Kuo, M; Dupuis, M; Henchoz, Y; Studer, J; N'Goran, A A; Gmel, G

    2016-09-01

    Social capital is described as a protective factor against youth substance use, but it may also be associated with behaviours that do not enhance health. The present study hypothesized that 'substance use capital', i.e. resources favourable to substance use, is a risk factor for substance use and misuse. We used baseline data from the ongoing Cohort Study on Substance Use Risk Factors (C-SURF) that included a representative sample of young Swiss men (n=5623). Substance use (alcohol, cannabis, 15 illicit drugs, lifetime use, hazardous use and dependence), substance use capital (parental and peer attitudes towards substance use, parental and peer drug use, perceived norms of substance use) and aspects of social capital (relationships with parents and peers) were assessed. Logistic regressions were used to examine the associations between substance-related resources and social resources, and substance use. Results showed that substance-related resources were associated with an increased risk of substance use (OR between 1.25 and 4.67), whereas social resources' associations with substance use were commonly protective but weaker than substance-related resources. Thus, a drug-friendly environment facilitated substance use and misuse. Moreover, the results showed that peer environments were more drug-friendly than familial environments. In conclusion, this study highlighted a concept of 'substance use capital', which may be useful for advancing both theoretical and applied knowledge of substance use. Indeed, substance use is not only associated with a lack of social resources, but also with specific drug-friendly social resources coming from environment and background. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  13. A Study on Substance Abuse Prevention

    ERIC Educational Resources Information Center

    Seçim, Gürcan

    2017-01-01

    This study aims to examine options to increase the supportive power of parents, teachers, school administrators, and counselors who directly interact with children and adolescents and have a fundamental responsibility to protect them from the risks of substance abuse and evaluate the effectiveness of associated training programs. The study design…

  14. Approaching Suspicious Substances Safely

    NASA Technical Reports Server (NTRS)

    2004-01-01

    A mineral identification tool that was developed for NASA's Mars Rover Technology Development program is now serving as a powerful tool for U.S. law enforcement agencies and military personnel to identify suspicious liquid and solid substances. The tool can measure unknown substances through glass and plastic packaging materials with the RamanProbe(TradeMark) focused fiber-optic probe. The probe length can be extended up to 200 meters to enable users to analyze potentially dangerous substances at a safe distance. In many cases, the spectrometer and personnel are kept in a safe zone while the probe is positioned next to the sample being analyzed. Being able to identify chemicals in remote locations also saves users time and labor, since otherwise the samples would need to be collected, transported, and prepared prior to measurement in the laboratory.

  15. Early Adolescent Substance Use/Abuse in Rural Northern Michigan.

    ERIC Educational Resources Information Center

    Sarvela, Paul D.; McClendon, E. J.

    Basic research and programs in substance abuse dealing directly with rural and small town populations lag far behind those aimed at urban groups, in both quality and quantity. A study was conducted to identify factors related to substance use by a preadolescent and early adolescent rural and small town population. Data were collected from 496…

  16. Top 40 priorities for science to inform conservation and management policy in the United States

    USGS Publications Warehouse

    Fleishman, Erica; Blockstein, David E.; Hall, John A.; Mascia, Michael B.; Rudd, Murray A.; Scott, J. Michael; Sutherland, William J.; Bartuska, Ann M.; Brown, A. Gordon; Christen, Catherine A.; Clement, Joel P.; DellaSala, Dominick; Duke, Clifford D.; Fiske, Shirley J.; Gosnell, Hannah; Haney, J. Chris; Hutchins, Michael; Klein, Mary L.; Marqusee, Jeffrey; Noon, Barry R.; Nordgren, John R.; Orbuch, Paul M.; Powell, Jimmie; Quarles, Steven P.; Saterson, Kathryn A.; Stein, Bruce A.; Webster, Michael S.; Vedder, Amy

    2011-01-01

    To maximize the utility of research to decisionmaking, especially given limited financial resources, scientists must set priorities for their efforts. We present a list of the top 40 high-priority, multidisciplinary research questions directed toward informing some of the most important current and future decisions about management of species, communities, and ecological processes in the United States. The questions were generated by an open, inclusive process that included personal interviews with decisionmakers, broad solicitation of research needs from scientists and policymakers, and an intensive workshop that included scientifically oriented individuals responsible for managing and developing policy related to natural resources. The process differed from previous efforts to set priorities for conservation research in its focus on the engagement of decisionmakers in addition to researchers. The research priorities emphasized the importance of addressing societal context and exploration of trade-offs among alternative policies and actions, as well as more traditional questions related to ecological processes and functions.

  17. 15 CFR 700.51 - Requests for priority rating authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Requests for priority rating authority... priority rating authority. (a) If a rated order is likely to be delayed because a person is unable to... priority rating in ordering the needed items. Examples of items for which priority ratings can be...

  18. Priority of discovery in the life sciences

    PubMed Central

    Vale, Ronald D; Hyman, Anthony A

    2016-01-01

    The job of a scientist is to make a discovery and then communicate this new knowledge to others. For a scientist to be successful, he or she needs to be able to claim credit or priority for discoveries throughout their career. However, despite being fundamental to the reward system of science, the principles for establishing the "priority of discovery" are rarely discussed. Here we break down priority into two steps: disclosure, in which the discovery is released to the world-wide community; and validation, in which other scientists assess the accuracy, quality and importance of the work. Currently, in biology, disclosure and an initial validation are combined in a journal publication. Here, we discuss the advantages of separating these steps into disclosure via a preprint, and validation via a combination of peer review at a journal and additional evaluation by the wider scientific community. PMID:27310529

  19. Playing Video Games While Using or Feeling the Effects of Substances: Associations with Substance Use Problems

    PubMed Central

    Ream, Geoffrey L.; Elliott, Luther C.; Dunlap, Eloise

    2011-01-01

    This study tested the hypothesis that playing video games while using or feeling the effects of a substance—referred to herein as “concurrent use”—is related to substance use problems after controlling for substance use frequency, video gaming as an enthusiastic hobby, and demographic factors. Data were drawn from a nationally representative online survey of adult video gamers conducted by Knowledge Networks, valid n = 2,885. Problem video game playing behavior was operationalized using Tejeiro Salguero and Bersabé Morán’s 2002 problem video game play (PVP) measure, and measures for substance use problems were taken from the National Survey of Drug Use and Health (NSDUH). Separate structural equation modeling analyses were conducted for users of caffeine, tobacco, alcohol, and marijuana. In all four models, concurrent use was directly associated with substance use problems, but not with PVP. Video gaming as an enthusiastic hobby was associated with substance use problems via two indirect paths: through PVP for all substances, and through concurrent use for caffeine, tobacco, and alcohol only. Results illustrate the potential for “drug interaction” between self-reinforcing behaviors and addictive substances, with implications for the development of problem use. PMID:22073023

  20. Violence against Native women in substance abuse treatment.

    PubMed

    Saylors, Karen; Daliparthy, Nalini

    2006-01-01

    Many mental health problems among substance abusing populations are directly linked to high rates of abuse and trauma. There is increasing evidence of associations between childhood physical and sexual abuse to adult substance use and HIV-risk behavior. The relationship of abuse, mental health problems, substance abuse, and high-risk sexual behavior has rarely been studied in the female Native American population. Significant relationships were found among childhood abuse, trauma, substance abuse, and high-risk sexual behavior among urban Native women.

  1. Setting practical conservation priorities for birds in the Western Andes of Colombia.

    PubMed

    Ocampo-Peñuela, Natalia; Pimm, Stuart L

    2014-10-01

    We aspired to set conservation priorities in ways that lead to direct conservation actions. Very large-scale strategic mapping leads to familiar conservation priorities exemplified by biodiversity hotspots. In contrast, tactical conservation actions unfold on much smaller geographical extents and they need to reflect the habitat loss and fragmentation that have sharply restricted where species now live. Our aspirations for direct, practical actions were demanding. First, we identified the global, strategic conservation priorities and then downscaled to practical local actions within the selected priorities. In doing this, we recognized the limitations of incomplete information. We started such a process in Colombia and used the results presented here to implement reforestation of degraded land to prevent the isolation of a large area of cloud forest. We used existing range maps of 171 bird species to identify priority conservation areas that would conserve the greatest number of species at risk in Colombia. By at risk species, we mean those that are endemic and have small ranges. The Western Andes had the highest concentrations of such species-100 in total-but the lowest densities of national parks. We then adjusted the priorities for this region by refining these species ranges by selecting only areas of suitable elevation and remaining habitat. The estimated ranges of these species shrank by 18-100% after accounting for habitat and suitable elevation. Setting conservation priorities on the basis of currently available range maps excluded priority areas in the Western Andes and, by extension, likely elsewhere and for other taxa. By incorporating detailed maps of remaining natural habitats, we made practical recommendations for conservation actions. One recommendation was to restore forest connections to a patch of cloud forest about to become isolated from the main Andes.

  2. Continuous Swarm Surveillance via Distributed Priority Maps

    NASA Astrophysics Data System (ADS)

    Howden, David

    With recent and ongoing improvements to unmanned aerial vehicle (UAV) endurance and availability, they are in a unique position to provide long term surveillance in risky environments. This paper presents a swarm intelligence algorithm for executing an exhaustive and persistent search of a non-trivial area of interest using a decentralized UAV swarm without long range communication. The algorithm allows for an environment containing arbitrary arrangements of no-fly zones, non-uniform levels of priority and dynamic priority changes in response to target acquisition or external commands. Performance is quantitatively analysed via comparative simulation with another leading algorithm of its class.

  3. Risks and Chemical Substances.

    ERIC Educational Resources Information Center

    Blumberg, Avrom A.

    1994-01-01

    Examines exposure to chemicals within the home and three important ways in which hazardous substances can be identified and evaluated. Suggests a rational picture of human health risks and contains an introductory discussion of reasons for exposure, epidemiology, cancer causes and patterns, animal testing, toxins, and risk. (LZ)

  4. Substance Use Prevention Project.

    ERIC Educational Resources Information Center

    Simmons, Judy

    This report outlines the Hillsborough County, Florida, Head Start Program's project to field test with young children and their families curricula that were designed to prevent alcohol and other drug problems. A national search conducted by means of computers, individual contacts, and other methods yielded information on 22 substance abuse…

  5. Adolescent Substance Abuse.

    ERIC Educational Resources Information Center

    Thorne, Craig R.; DeBlassie, Richard R.

    1985-01-01

    Cummings (1979), citing evidence from the National Institute of Drug Abuse, reports that one of every eleven adult Americans suffers from a severe addictive problem. Drug addiction is epidemic among teenagers; one of every six teenagers suffers from a severe addictive problem. This paper focuses on adolescent drug/substance abuse. (Author)

  6. Substance abuse in women.

    PubMed

    Greenfield, Shelly F; Back, Sudie E; Lawson, Katie; Brady, Kathleen T

    2010-06-01

    Gender differences in substance use disorders (SUDs) and treatment outcomes for women with SUDs have been a focus of research in the last 15 years. This article reviews gender differences in the epidemiology of SUDs, highlighting the convergence of male/female prevalence ratios of SUDs in the last 20 years. The telescoping course of SUDs, recent research on the role of neuroactive gonadal steroid hormones in craving and relapse, and sex differences in stress reactivity and relapse to substance abuse are described. The role of co-occurring mood and anxiety, eating, and posttraumatic stress disorders is considered in the epidemiology, natural history, and treatment of women with SUDs. Women's use of alcohol, stimulants, opioids, cannabis, and nicotine are examined in terms of recent epidemiology, biologic and psychosocial effects, and treatment. Although women may be less likely to enter substance abuse treatment than men over the course of the lifetime, once they enter treatment, gender itself is not a predictor of treatment retention, completion, or outcome. Research on gender-specific treatments for women with SUDs and behavioral couples treatment has yielded promising results for substance abuse treatment outcomes in women. Copyright 2010 Elsevier Inc. All rights reserved.

  7. Adolescent Substance Abuse.

    ERIC Educational Resources Information Center

    Thorne, Craig R.; DeBlassie, Richard R.

    1985-01-01

    Cummings (1979), citing evidence from the National Institute of Drug Abuse, reports that one of every eleven adult Americans suffers from a severe addictive problem. Drug addiction is epidemic among teenagers; one of every six teenagers suffers from a severe addictive problem. This paper focuses on adolescent drug/substance abuse. (Author)

  8. Risks and Chemical Substances.

    ERIC Educational Resources Information Center

    Blumberg, Avrom A.

    1994-01-01

    Examines exposure to chemicals within the home and three important ways in which hazardous substances can be identified and evaluated. Suggests a rational picture of human health risks and contains an introductory discussion of reasons for exposure, epidemiology, cancer causes and patterns, animal testing, toxins, and risk. (LZ)

  9. Substance Abuse and Counseling.

    ERIC Educational Resources Information Center

    Sales, Amos, Ed.

    This book focuses on the identification of practical knowledge and skills needed for counseling individuals with substance abuse problems. It is a resource for practitioners, students, and faculty in school counseling, rehabilitation counseling, mental health counseling, school psychology, or social work in recognizing, preventing, and treating…

  10. Substance Use as a Longitudinal Predictor of the Perpetration of Teen Dating Violence

    ERIC Educational Resources Information Center

    Temple, Jeff R.; Shorey, Ryan C.; Fite, Paula; Stuart, Gregory L.; Le, Vi Donna

    2013-01-01

    The prevention of teen dating violence is a major public health priority. However, the dearth of longitudinal studies makes it difficult to develop programs that effectively target salient risk factors. Using a school-based sample of ethnically diverse adolescents, this longitudinal study examined whether substance use (alcohol, marijuana, and…

  11. Substance Use as a Longitudinal Predictor of the Perpetration of Teen Dating Violence

    ERIC Educational Resources Information Center

    Temple, Jeff R.; Shorey, Ryan C.; Fite, Paula; Stuart, Gregory L.; Le, Vi Donna

    2013-01-01

    The prevention of teen dating violence is a major public health priority. However, the dearth of longitudinal studies makes it difficult to develop programs that effectively target salient risk factors. Using a school-based sample of ethnically diverse adolescents, this longitudinal study examined whether substance use (alcohol, marijuana, and…

  12. [Newborn-child of substance dependent mother--always actual problem].

    PubMed

    Syweńki, Ewa; Lipińska-Gediga, Małgorzata

    2009-01-01

    The adverse effects on fetal development of alcohol and other drugs such as tobacco, psychostimulants and opioids are well known. Women who are pregnant or who may become pregnant are therefore a high priority for interventions to reduce drug use. Substances discussed in this article include the licit substances (alcohol and tobacco), illicit substances (opioids and other drugs), and prescription medication known for its misuse (benzodiazepines and barbiturates). Other topics covered include breastfeeding, vertical transmission of blood-borne viruses, psychosocial issues, the management of neonatal abstinence syndrome and early childhood development.

  13. 78 FR 45064 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... confirmatory sampling verified that VOC contaminated soil removal to the remedial design excavation levels was... removal quantities were sufficient to satisfy the specified clean-up levels as verified by the... levels that allow for unlimited use and unrestricted exposure. EPA conducts such five-year reviews...

  14. 76 FR 50414 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... February 1986, NJDEP engaged B&V Waste Science and Technology, Inc. (BVWST) to begin a remedial... 17 drums of liquid waste were transported off site by Waste Minimization Sciences, Inc. on April 30... level or have decreased to non-detect. In 2008, a forensic analysis of methane from P-6A and landfill...

  15. 77 FR 43529 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... provides EPA's rationale for deleting the Site from the NPL: Site Background and History The Fort Dix... Engineers Waterways Experiment Station. VOCs and heavy metals were detected in the groundwater samples... burrowing animals are repaired as needed. The sediment and erosion control features are maintained by...

  16. 75 FR 54779 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    .... Metals & Iron). OU2 Rocky Mountain Research 1020-1030 Yuma Street. Corporation (now A1 Transmission and... of the Schlesinger Radium Company which began operations in 1914 where Atlas Metals & Iron (formerly... contaminated soil on the northeast part of the Atlas Metals & Iron (formerly DuWald Steel Corporation) property...

  17. 75 FR 48867 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ...-site soil and about 30 decaying drums were found to be contaminated with dioxin (2,3,7,8... Study (FS) was also released at this time (Peer and Resource Applications, 1990b). Onsite soil and... undertaken at the Rogers Road landfill revealed that contaminants in the soil comprised the principal threat...

  18. 77 FR 50038 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ...://www.regulations.gov Web site is an ``anonymous access'' system, which means EPA will not know your... maps for the eight monitored flow zones; groundwater quality data; groundwater flow budget and particle...

  19. 76 FR 510 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... Plant (facility) where creosote and other compounds were used in the wood preservation process. The... a wood pressure treatment plant from March 1908 to January 1972. The facility primarily used...% pentachlorophenol. In 1972, the plant was totally dismantled, and the only physical feature remaining on-site was...

  20. 78 FR 49993 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    .... Email: Nefertiti DiCosmo, Remedial Project Manager, at mailto: dicosmo.nefertiti@epa.gov or Dave Novak, Community Involvement Coordinator, at novak.dave@epa.gov . Fax: Gladys Beard at (312) 697-2077. Mail... Boulevard, Chicago, IL 60604, (312) 886-6148 or Dave Novak, Community Involvement Coordinator, U.S...

  1. 75 FR 43082 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... Superfund. This partial deletion pertains to the soil and groundwater of parcels 24, 27, 28, 2-53, 2-53L, 2... groundwater of parcels 24, 27, 28, 2-53, 2- 53L, 2-54, 2-54L, 2-70, 2-70L, 3-89, 3-90, and 3-91. The NPL... Office (PDO) Area. These two areas are separated by a major groundwater/surface-water drainage divide...

  2. 77 FR 37630 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... groundwater also included VOCs, SVOCs, and metals. Contaminants were found in both the shallow and deep zones... aquifer. The health risk posed by this NPL site is primarily from the future use of the groundwater as a... drinking water and the State of North Carolina groundwater quality standards. The Feasibility Study (FS...

  3. 78 FR 70231 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ..., which focused on surface soil, subsurface soil, groundwater, surface water, sediments, landfill waste... monitoring of groundwater. During the drafting of the feasibility study (FS), the PRPs requested that the... ROD selected the following remedy: 1. Installation of two groundwater monitoring wells to augment the...

  4. 77 FR 45968 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-02

    ... under Superfund. This partial deletion pertains to all Site media (soil and groundwater) of the... List (NPL). This partial deletion pertains to all site media, including soil and groundwater for the... were contaminated with chlorinated benzene compounds. Groundwater was contaminated at concentrations...

  5. 75 FR 54821 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List; Intent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... issuing a Notice of Intent to Delete each of the 11 operable units, with the exception of groundwater... on this proposed action. Groundwater associated with Operable Unit 8 will remain on the NPL. The NPL... each of the 11 operable units of the Denver Radium Superfund Site. Groundwater contamination associated...

  6. 78 FR 24134 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... solid waste management units (SWMUs) located throughout the Facility. To simplify the response efforts... Health and Environmental Control (SCDHEC), Bureau of Land and Waste Management Resource Conservation and... corrective action requirements of the South Carolina Hazardous and Solid Waste Amendments (HSWA) portion...

  7. 75 FR 26131 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ..., grading the asbestos- containing material (ACM) to the required elevations, installation of a layer of... constructed over the ACM waste and institutional controls, is protective and will remain protective of human health and the environment. Solidification and stabilization of the ACM was incorporated into the...

  8. 75 FR 27192 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ..., asbestos containing material (ACM), and slag waste identified as a characteristic hazardous waste because... concern. Also present at the Site was a UST with unknown contents, ACM, and slag waste identified as a... disposal of ACM and the UST, and the excavation, treatment, and offsite disposal of hazardous wastes....

  9. 76 FR 45428 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ....regulations.gov Web site is an ``anonymous access'' system, which means EPA will not know your identity or... and six deep borings ranging in depths from 4.0 to 9.0 and 25.0 to 60.0 feet below the ground's...

  10. 76 FR 20546 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    .... The http://www.regulations.gov Web site is an ``anonymous access'' system, which means EPA will not... monitoring period consisted of twelve monitoring events from wells in the shallow and deep aquifer both...

  11. 77 FR 67777 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ... http://www.regulations.gov or email. The http://www.regulations.gov Web site is an ``anonymous access... IRA. An area 400 feet by 70 feet by 1.5 feet deep was excavated, removing approximately 1,433 cubic...

  12. 75 FR 44920 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ... contaminated groundwater. It should be noted that, due to frequent clogging of the injection wells, permission was granted (from the Town of Babylon) to discontinue use of the injection wells and discharge the... gallons per minute (gpm), pumped from two extraction wells. The system was in almost continuous operation...

  13. 78 FR 45871 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ..., which is the only aquifer that could potentially be developed for drinking water supply. This evaluation... determined that all appropriate response actions under CERCLA, other than operation, maintenance, and Five... components: Hydrogeologic study; Surface water sampling study; Stream biological study; Air quality survey...

  14. 78 FR 47205 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... Refining Co. Superfund Site (CERCLIS ID OK0002024099) is the location of a former petroleum refinery that... of Hwy 142 is occupied by a facility that manufactures roofing shingles. Waste-water processing..., sediment, waste pile, and surface water samples were collected. There were numerous pits, piles, and...

  15. 75 FR 53222 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... appear to present a significant risk to public health, welfare, or the environment. Sites on the NPL may... the environment and, therefore, the taking of remedial measures is not appropriate. Pursuant to CERCLA.... Disposal records indicate that pesticide manufacturing wastes were disposed in the landfill until 1978. In...

  16. 78 FR 33276 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... dwellings, apartment complexes, child-care facilities, vacant lots in residential areas, schools, churches, community centers, parks, greenways, and any other areas where children may be exposed to site-related... properties, child-care centers, and other residential-type properties in the city of Omaha, Douglas County...

  17. 75 FR 34405 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... (1991). OU 17: CERCLA Wastewater Treatment Plant IRA--Facility constructed to treat wastewater generated... CERCLA Wastewater Treatment Facility and the Landfill Wastewater Treatment System (LWTS). The following... Treatment Facility in Section 36, which was constructed to treat remedy-generated wastewater. The CERCLA...

  18. 78 FR 69302 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... (') to 33 41' north latitude,117 41' to 117 45' west longitude, Township 6 South, Range 6 West (T6S/R6W... land was acquired to bring the size of the on-station portion of the installation to 4,712 acres. Major... containing both hazardous and solid waste, and other areas where polychlorinated biphenyls (PCBs), battery...

  19. 78 FR 70256 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ... comment includes information claimed to be Confidential Business Information (CBI) or other information....bernard@epa.gov . SUPPLEMENTARY INFORMATION: In the ``Rules and Regulations'' section of today's...

  20. 76 FR 51266 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... agreed to implement the remedy which was selected in the ROD. The SDs hired M&S Ingenieria y Ciencia.... On December 16, 1999, EPA approved the Remedial Action Work Plan and M&S Ingenieria y Ciencia...