Computer Languages: A Practical Guide to the Chief Programming Languages.

ERIC Educational Resources Information Center

Sanderson, Peter C.

All the most commonly-used high-level computer languages are discussed in this book. An introductory discussion provides an overview of the basic components of a digital computer, the general planning of a computer programing problem, and the various types of computer languages. Each chapter is self-contained, emphasizes those features of a…

CIRCAL-2 - General-purpose on-line circuit design.

NASA Technical Reports Server (NTRS)

Dertouzos, M. L.; Jessel, G. P.; Stinger, J. R.

1972-01-01

CIRCAL-2 is a second-generation general-purpose on-line circuit-design program with the following main features: (1) multiple-analysis capability; (2) uniform and general data structures for handling text editing, network representations, and output results, regardless of analysis; (3) special techniques and structures for minimizing and controlling user-program interaction; (4) use of functionals for the description of hysteresis and heat effects; and (5) ability to define optimization procedures that 'replace' the user. The paper discusses the organization of CIRCAL-2, the aforementioned main features, and their consequences, such as a set of network elements and models general enough for most analyses and a set of functions tailored to circuit-design requirements. The presentation is descriptive, concentrating on conceptual rather than on program implementation details.

Man's role in integrated control and information management systems

NASA Technical Reports Server (NTRS)

Nevins, J. L.; Johnson, I. S.

1972-01-01

Display control considerations associated with avionics techniques are discussed. General purpose displays and a prototype interactive display/command design featuring a pushplate CRT overlay for command input are considered.

A feature-based inference model of numerical estimation: the split-seed effect.

PubMed

Murray, Kyle B; Brown, Norman R

2009-07-01

Prior research has identified two modes of quantitative estimation: numerical retrieval and ordinal conversion. In this paper we introduce a third mode, which operates by a feature-based inference process. In contrast to prior research, the results of three experiments demonstrate that people estimate automobile prices by combining metric information associated with two critical features: product class and brand status. In addition, Experiments 2 and 3 demonstrated that when participants are seeded with the actual current base price of one of the to-be-estimated vehicles, they respond by revising the general metric and splitting the information carried by the seed between the two critical features. As a result, the degree of post-seeding revision is directly related to the number of these features that the seed and the transfer items have in common. The paper concludes with a general discussion of the practical and theoretical implications of our findings.

The role of experiential avoidance, psychopathology, and borderline personality features in experiencing positive emotions: a path analysis.

PubMed

Jacob, Gitta A; Ower, Nicole; Buchholz, Angela

2013-03-01

Experiential avoidance (EA) is an important factor in maintaining different forms of psychopathology including borderline personality pathology (BPD). So far little is known about the functions of EA, BPD features and general psychopathology for positive emotions. In this study we investigated three different anticipated pathways of their influence on positive emotions. A total of 334 subjects varying in general psychopathology &/or BPD features completed an online survey including self-ratings of BPD features, psychopathology, negative and positive emotions, and EA. Measures of positive emotions included both a general self-rating (PANAS) and emotional changes induced by two positive movie clips. Data were analyzed by means of path analysis. In comparing the three path models, one model was found clearly superior: In this model, EA acts as a mediator of the influence of psychopathology, BPD features, and negative emotions in the prediction of both measures of positive emotions. EA plays a central role in maintaining lack of positive emotions. Therapeutic implications and study limitations are discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.

Space solar power systems

NASA Technical Reports Server (NTRS)

Toliver, C.

1977-01-01

Studies were done on the feasibility of placing a solar power station called POwersat, in space. A general description of the engineering features are given as well as a brief discussion of the economic considerations.

Information Technology.

ERIC Educational Resources Information Center

Marcum, Deanna; Boss, Richard

1982-01-01

Discusses four automated serials control systems which have been installed by at least six general libraries: OCLC's Serials Control Subsystem, Faxon's LINX, Ebsco's EBSCONET, and CLASS' CHECKMATE. Features of each system, accessibility, and costs are noted. (EJS)

Gathering Momentum! Transition from School to Work. Featuring Profiles of 23 Ohio Programs.

ERIC Educational Resources Information Center

Gifford, Bev

This report examines the provisions of the School-to-Work Opportunities Act and describes the steps that have been taken thus far to establish an Ohio system. It discusses the general features that must be included in Ohio's school-to-work system and the strategies around which Ohio's school-to-work plans are being structured. Recommendations are…

Mapping accuracy via spectrally and structurally based filtering techniques: comparisons through visual observations

NASA Astrophysics Data System (ADS)

Chockalingam, Letchumanan

2005-01-01

The data of Gunung Ledang region of Malaysia acquired through LANDSAT are considered to map certain hydrogeolocial features. To map these significant features, image-processing tools such as contrast enhancement, edge detection techniques are employed. The advantages of these techniques over the other methods are evaluated from the point of their validity in properly isolating features of hydrogeolocial interest are discussed. As these techniques take the advantage of spectral aspects of the images, these techniques have several limitations to meet the objectives. To discuss these limitations, a morphological transformation, which generally considers the structural aspects rather than spectral aspects from the image, are applied to provide comparisons between the results derived from spectral based and the structural based filtering techniques.

Problem-Based Learning in Web-Based Science Classroom.

ERIC Educational Resources Information Center

Kim, Heeyoung; Chung, Ji-Sook; Kim, Younghoon

The purpose of this paper is to discuss how general problem-based learning (PBL) models and social-constructivist perspectives are applied to the design and development of a Web-based science program, which emphasizes inquiry-based learning for fifth grade students. The paper also deals with the general features and learning process of a Web-based…

A Course on Multimedia Environmental Transport, Exposure, and Risk Assessment.

ERIC Educational Resources Information Center

Cohen, Yoram; And Others

1990-01-01

Included are the general guidelines, outline, a summary of major intermedia transport processes, model features, a discussion of multimedia exposure and health risk, and a list of 50 suggested references for this course. (CW)

Potential of Diesel Engine, Emission Technology

DOT National Transportation Integrated Search

1980-03-01

This report surveys diesel engine emission technologies applicable to passenger cars and light trucks. The general design and operating features are presented and discussed. Current and state-of-the-art concepts are reviewed with the focus on control...

Fifteenth NASTRAN (R) Users' Colloquium

NASA Technical Reports Server (NTRS)

1987-01-01

Numerous applications of the NASA Structural Analysis (NASTRAN) computer program, a general purpose finite element code, are discussed. Additional features that can be added to NASTRAN, interactive plotting of NASTRAN data on microcomputers, mass modeling for bars, the design of wind tunnel models, the analysis of ship structures subjected to underwater explosions, and buckling analysis of radio antennas are among the topics discussed.

Improvisation in the Disorders of Desire: Performativity, Passion and Moral Education

ERIC Educational Resources Information Center

Munday, Ian

2010-01-01

In this article, I attempt to bring some colour to a discussion of fraught topics in education. Though the scenes and stories (from education and elsewhere) that feature here deal with racism, the discussion aims to say something to such topics more generally. The philosophers whose work I draw on here are Stanley Cavell and Judith Butler. Both…

Support-vector-based emergent self-organising approach for emotional understanding

NASA Astrophysics Data System (ADS)

Nguwi, Yok-Yen; Cho, Siu-Yeung

2010-12-01

This study discusses the computational analysis of general emotion understanding from questionnaires methodology. The questionnaires method approaches the subject by investigating the real experience that accompanied the emotions, whereas the other laboratory approaches are generally associated with exaggerated elements. We adopted a connectionist model called support-vector-based emergent self-organising map (SVESOM) to analyse the emotion profiling from the questionnaires method. The SVESOM first identifies the important variables by giving discriminative features with high ranking. The classifier then performs the classification based on the selected features. Experimental results show that the top rank features are in line with the work of Scherer and Wallbott [(1994), 'Evidence for Universality and Cultural Variation of Differential Emotion Response Patterning', Journal of Personality and Social Psychology, 66, 310-328], which approached the emotions physiologically. While the performance measures show that using the full features for classifications can degrade the performance, the selected features provide superior results in terms of accuracy and generalisation.

Parent ads in the National Youth Anti-Drug Media Campaign.

PubMed

Stephenson, Michael T; Quick, Brian L

2005-12-01

The National Youth Anti-Drug Media Campaign aims not only to reduce drug use by teens and preteens, but also to arm parents with knowledge about specific parenting practices known to reduce the risk of teen drug use. Among the documented successes of the campaign to date was a small, but direct effect on some parenting practices, including parent-child discussions about drug use. To reach a deeper understanding about the substance of the parental ads, we content analyzed the message strategies employed in the campaign's parent ads over the inaugural 5 years of the campaign. Each ad was coded for its major theme, minor subtheme, and featured drug. Among seven possible major themes, the parental anti-drug ads largely featured four: enhance the risk of their child's drug use, encourage monitoring practices, promote parent-child discussions about drug use, or advocate positive involvement behaviors. Moreover, most parental messages addressed marijuana use or addressed drug use in general. Marijuana and inhalant ads largely were risk based, while general drug messages focused on monitoring, parent-child discussions or positive involvement practices.

Foxes and Rabbits - and a Spreadsheet.

ERIC Educational Resources Information Center

Carson, S. R.

1996-01-01

Presents a numerical simulation of a simple food chain together with a set of mathematical rules generalizing the model to a food web of any complexity. Discusses some of the model's interesting features and its use by students. (Author/JRH)

Generalization of uncertainty relation for quantum and stochastic systems

NASA Astrophysics Data System (ADS)

Koide, T.; Kodama, T.

2018-06-01

The generalized uncertainty relation applicable to quantum and stochastic systems is derived within the stochastic variational method. This relation not only reproduces the well-known inequality in quantum mechanics but also is applicable to the Gross-Pitaevskii equation and the Navier-Stokes-Fourier equation, showing that the finite minimum uncertainty between the position and the momentum is not an inherent property of quantum mechanics but a common feature of stochastic systems. We further discuss the possible implication of the present study in discussing the application of the hydrodynamic picture to microscopic systems, like relativistic heavy-ion collisions.

Special electrical machines: Sources and converters of energy

NASA Astrophysics Data System (ADS)

Bertinov, A. I.; But, D. A.; Miziurin, S. R.; Alievskii, B. L.; Sineva, N. V.

The principles underlying the operation of electromechanical and dynamic energy converters are discussed, along with those for the direct conversion of solar, thermal, and chemical energy into electrical energy. The theory for electromechanical and dynamic converters is formulated using a generalized model for the electromechanical conversion of energy. Particular attention is given to electrical machinery designed for special purposes. Features of superconductor electrical machines are discussed.

The Grammaticalization of the Proximative in Tok Pisin.

ERIC Educational Resources Information Center

Romaine, Suzanne

1999-01-01

Discusses grammaticalization of "laik" in Tok Pisin, meaning "want/like/desire" (from English "like") and "klostu," meaning "near" (from English "close to") as markers of proximative. Shows although "klostu" was more generally a feature of Pacific Pidgin English and began to…

Simulation of the space station information system in Ada

NASA Technical Reports Server (NTRS)

Spiegel, James R.

1986-01-01

The Flexible Ada Simulation Tool (FAST) is a discrete event simulation language which is written in Ada. FAST has been used to simulate a number of options for ground data distribution of Space Station payload data. The fact that Ada language is used for implementation has allowed a number of useful interactive features to be built into FAST and has facilitated quick enhancement of its capabilities to support new modeling requirements. General simulation concepts are discussed, and how these concepts are implemented in FAST. The FAST design is discussed, and it is pointed out how the used of the Ada language enabled the development of some significant advantages over classical FORTRAN based simulation languages. The advantages discussed are in the areas of efficiency, ease of debugging, and ease of integrating user code. The specific Ada language features which enable these advances are discussed.

A Course for Engineering and Science Students

ERIC Educational Resources Information Center

Companion, A.; Schug, K.

1973-01-01

Discusses the features of a course which emphasizes training of scientists and engineers with broad interdisciplinary knowledge in addition to those with a highly specialized professional preparation. Included is a list of books relating to applications of materials science concepts in general chemistry. (CC)

Intelligent interface design and evaluation

NASA Technical Reports Server (NTRS)

Greitzer, Frank L.

1988-01-01

Intelligent interface concepts and systematic approaches to assessing their functionality are discussed. Four general features of intelligent interfaces are described: interaction efficiency, subtask automation, context sensitivity, and use of an appropriate design metaphor. Three evaluation methods are discussed: Functional Analysis, Part-Task Evaluation, and Operational Testing. Design and evaluation concepts are illustrated with examples from a prototype expert system interface for environmental control and life support systems for manned space platforms.

Scale Insects, edition 2, a tool for the identification of potential pest scales at U.S.A. ports-of-entry (Hemiptera, Sternorrhyncha, Coccoidea)

PubMed Central

Miller, Douglass R.; Rung, Alessandra; Parikh, Grishma

2014-01-01

Abstract We provide a general overview of features and technical specifications of an online, interactive tool for the identification of scale insects of concern to the U.S.A. ports-of-entry. Full lists of terminal taxa included in the keys (of which there are four), a list of features used in them, and a discussion of the structure of the tool are provided. We also briefly discuss the advantages of interactive keys for the identification of potential scale insect pests. The interactive key is freely accessible on http://idtools.org/id/scales/index.php PMID:25152668

Network simulation using the simulation language for alternate modeling (SLAM 2)

NASA Technical Reports Server (NTRS)

Shen, S.; Morris, D. W.

1983-01-01

The simulation language for alternate modeling (SLAM 2) is a general purpose language that combines network, discrete event, and continuous modeling capabilities in a single language system. The efficacy of the system's network modeling is examined and discussed. Examples are given of the symbolism that is used, and an example problem and model are derived. The results are discussed in terms of the ease of programming, special features, and system limitations. The system offers many features which allow rapid model development and provides an informative standardized output. The system also has limitations which may cause undetected errors and misleading reports unless the user is aware of these programming characteristics.

Cognitive Architectures and Autonomy: A Comparative Review

NASA Astrophysics Data System (ADS)

Thórisson, Kristinn; Helgasson, Helgi

2012-05-01

One of the original goals of artificial intelligence (AI) research was to create machines with very general cognitive capabilities and a relatively high level of autonomy. It has taken the field longer than many had expected to achieve even a fraction of this goal; the community has focused on building specific, targeted cognitive processes in isolation, and as of yet no system exists that integrates a broad range of capabilities or presents a general solution to autonomous acquisition of a large set of skills. Among the reasons for this are the highly limited machine learning and adaptation techniques available, and the inherent complexity of integrating numerous cognitive and learning capabilities in a coherent architecture. In this paper we review selected systems and architectures built expressly to address integrated skills. We highlight principles and features of these systems that seem promising for creating generally intelligent systems with some level of autonomy, and discuss them in the context of the development of future cognitive architectures. Autonomy is a key property for any system to be considered generally intelligent, in our view; we use this concept as an organizing principle for comparing the reviewed systems. Features that remain largely unaddressed in present research, but seem nevertheless necessary for such efforts to succeed, are also discussed.

Some problems of human adaptation and ecology under the aspect of general pathology

NASA Technical Reports Server (NTRS)

Kaznacheyev, V. P.

1980-01-01

The main problems of human adaptation at the level of the body and the population in connection with the features of current morbidity of the population and certain demographic processes are analyzed. The concepts of health and adaptation of the individual and human populations are determined. The importance of the anthropo-ecological approach to the investigation of the adaptation process of human populations is demonstrated. Certain features of the etiopathogenesis of diseases are considered in connection with the population-ecological regularities of human adaptation. The importance of research on general pathology aspects of adaptation and the ecology of man for planning, and organization of public health protection is discussed.

Feature highlighting enhances learning of a complex natural-science category.

PubMed

Miyatsu, Toshiya; Gouravajhala, Reshma; Nosofsky, Robert M; McDaniel, Mark A

2018-04-26

Learning naturalistic categories, which tend to have fuzzy boundaries and vary on many dimensions, can often be harder than learning well defined categories. One method for facilitating the category learning of naturalistic stimuli may be to provide explicit feature descriptions that highlight the characteristic features of each category. Although this method is commonly used in textbooks and classrooms, theoretically it remains uncertain whether feature descriptions should advantage learning complex natural-science categories. In three experiments, participants were trained on 12 categories of rocks, either without or with a brief description highlighting key features of each category. After training, they were tested on their ability to categorize both old and new rocks from each of the categories. Providing feature descriptions as a caption under a rock image failed to improve category learning relative to providing only the rock image with its category label (Experiment 1). However, when these same feature descriptions were presented such that they were explicitly linked to the relevant parts of the rock image (feature highlighting), participants showed significantly higher performance on both immediate generalization to new rocks (Experiment 2) and generalization after a 2-day delay (Experiment 3). Theoretical and practical implications are discussed. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Adapting Local Features for Face Detection in Thermal Image.

PubMed

Ma, Chao; Trung, Ngo Thanh; Uchiyama, Hideaki; Nagahara, Hajime; Shimada, Atsushi; Taniguchi, Rin-Ichiro

2017-11-27

A thermal camera captures the temperature distribution of a scene as a thermal image. In thermal images, facial appearances of different people under different lighting conditions are similar. This is because facial temperature distribution is generally constant and not affected by lighting condition. This similarity in face appearances is advantageous for face detection. To detect faces in thermal images, cascade classifiers with Haar-like features are generally used. However, there are few studies exploring the local features for face detection in thermal images. In this paper, we introduce two approaches relying on local features for face detection in thermal images. First, we create new feature types by extending Multi-Block LBP. We consider a margin around the reference and the generally constant distribution of facial temperature. In this way, we make the features more robust to image noise and more effective for face detection in thermal images. Second, we propose an AdaBoost-based training method to get cascade classifiers with multiple types of local features. These feature types have different advantages. In this way we enhance the description power of local features. We did a hold-out validation experiment and a field experiment. In the hold-out validation experiment, we captured a dataset from 20 participants, comprising 14 males and 6 females. For each participant, we captured 420 images with 10 variations in camera distance, 21 poses, and 2 appearances (participant with/without glasses). We compared the performance of cascade classifiers trained by different sets of the features. The experiment results showed that the proposed approaches effectively improve the performance of face detection in thermal images. In the field experiment, we compared the face detection performance in realistic scenes using thermal and RGB images, and gave discussion based on the results.

Glovebox in orbit - ESA/NASA Glovebox: A versatile USML-1 experiment facility

NASA Technical Reports Server (NTRS)

Sutherland, Ian A.; Wolff, Heinz; Helmke, Hartmut; Riesselmann, Werner; Nagy, Mike; Voeten, Eduard; Chassay, Roger

1993-01-01

The general purpose experiment facility flown aboard Space Shuttle USML-1 and known as the Glovebox is briefly discussed. Glovebox enabled scientists to perform materials science, fluids, and combustion experiments safely without contaminating the closed environment of Spacelab and endangering the crew. The evolution of Glovebox, its special features, and its hardware are described. The Glovebox experiments are summarized along with postmission and crew debriefing. Future uses of Glovebox are discussed.

Business Magazines Online: The Big Three on the Three--and More.

ERIC Educational Resources Information Center

Marcus, John

1995-01-01

Describes features of the three major general business magazines and the online services they are currently associated with: "Business Week," which is available through America Online; "Fortune," available through CompuServe; and "Forbes," which has just become available through CompuServe. Discusses search features…

Funding of drugs: do vaccines warrant a different approach?

PubMed

Beutels, Philippe; Scuffham, Paul A; MacIntyre, C Raina

2008-11-01

Vaccines have features that require special consideration when assessing their cost-effectiveness. These features are related to herd immunity, quality-of-life losses in young children, parental care and work loss, time preference, uncertainty, eradication, macroeconomics, and tiered pricing. Advisory committees on public funding for vaccines, or for pharmaceuticals in general, should be knowledgable about these special features. We discuss key issues and difficulties in decision making for vaccines against rotavirus, human papillomavirus, varicella-zoster virus, influenza virus, and Streptococcus pneumoniae. We argue that guidelines for economic evaluation should be reconsidered generally to recommend (1) modelling options for the assessment of interventions against infectious diseases; (2) a wider perspective to account for impacts on third parties, if relevant; (3) a wider scope of costs than health-care system costs alone, if appropriate; and (4) alternative discounting techniques to explore social time preference over long periods.

An update on dental imaging.

PubMed

Whaites, E; Brown, J

1998-08-22

This paper reviews recent advances and current trends in dental radiology. Developments in the design of dental x-ray equipment which improve both radiation hygiene and image quality are described. Also discussed are new features which broaden the scope of intra-oral and panoramic radiological diagnosis in the general dental practice setting. The article concludes with the main recommendations from the latest guidelines on quality standards for radiography, selection criteria and quality assurance in general practice.

HyperCard--A Science Teaching Tool.

ERIC Educational Resources Information Center

Parker, Carol

1992-01-01

Discussion of new technological resources available for science instruction focuses on the use of the HyperCard software for the Macintosh to design customized materials. Topics addressed include general features of HyperCard, designing HyperCard stacks, graphics, and designing buttons (i.e., links for moving through the stacks). Several sample…

Culturally Responsive Practices for Culturally and Linguistically Diverse Students with Learning Disabilities

ERIC Educational Resources Information Center

Utley, Cheryl A.; Obiakor, Festus E.; Bakken, Jeffrey P.

2011-01-01

This article discusses culturally responsive frameworks, principles, pedagogy, and curriculum for general and special educators who work with culturally and linguistically diverse (CLD) students with learning disabilities (LD). Culturally responsive teaching has critical features that could benefit CLD students with LD. For example, culturally…

Treatment of Epilepsy in Children with Developmental Disabilities

ERIC Educational Resources Information Center

Depositario-Cabacar, Dewi Frances T.; Zelleke, Tesfaye-Getaneh

2010-01-01

Children with developmental disabilities are at increased risk for epilepsy with a prevalence rate higher than the general population. Some of the more common developmental disorders in childhood and the features of epilepsy in these conditions are discussed. Specifically, autism, cerebral palsy, mental retardation, and attention deficit and…

Rapporteur-General's Oral Report.

ERIC Educational Resources Information Center

Wiltshire, Kenneth

An international congress produced discussion and debate regarding the factors that will shape technical and vocational education in the new century and the new millennium. Speakers declared that the 21st century will be an era of knowledge, information, and civilization. According to the speakers, key features of the 21st century will include…

The Patients in Recovery (PIR) Perspective: Teaching Physicians about Methamphetamine

ERIC Educational Resources Information Center

Walley, Alexander Y.; Phillips, Karran A.; Gordon, Adam J.

2008-01-01

Methamphetamine dependence is an emerging epidemic confronting physicians. In an effort to improve understanding of its impact, the authors presented an educational workshop at a national meeting for general internists featuring small group discussions with patients in recovery (PIR) from methamphetamine dependence. Participants rated the workshop…

Development of Distinctive Feature Theory.

ERIC Educational Resources Information Center

Meyer, Peggy L.

Since the beginning of man's awareness of his language capabilities and language structure, he has assumed that speech is composed of discrete entities. The linguist attempts to establish a model of the workings of these distinctive sounds in a language. Utilizing an historical basis for discussion, this general survey of the distinctive feature…

Nuclear Power Plants. Revised.

ERIC Educational Resources Information Center

Lyerly, Ray L.; Mitchell, Walter, III

This publication is one of a series of information booklets for the general public published by the United States Atomic Energy Commission. Among the topics discussed are: Why Use Nuclear Power?; From Atoms to Electricity; Reactor Types; Typical Plant Design Features; The Cost of Nuclear Power; Plants in the United States; Developments in Foreign…

Economic Issues in Mass Communication Industries.

ERIC Educational Resources Information Center

Rosse, James N.; Dertouzos, James N.

A general discussion covering both the common problems and features of the full range of the mass media industries, and some economic notions central to understanding them, opens this report, followed by introductory essays for individual industries and consideration of public policy issues. The basic economic considerations common to the field…

Sobre prestamos y clasificaciones linguisticas (Regarding Borrowing and Linguistic Classification).

ERIC Educational Resources Information Center

Key, Mary Ritchie

1988-01-01

This article explores the traditionally accepted etymologies of several lexical borrowings in the indigenous languages of the Americas within the framework of comparative linguistics and linguistic classification. The first section presents a general discussion of the problem of tracing lexical borrowings in this context. The section features a…

Measurement incompatibility and Schrödinger-Einstein-Podolsky-Rosen steering in a class of probabilistic theories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Banik, Manik, E-mail: manik11ju@gmail.com

Steering is one of the most counter intuitive non-classical features of bipartite quantum system, first noticed by Schrödinger at the early days of quantum theory. On the other hand, measurement incompatibility is another non-classical feature of quantum theory, initially pointed out by Bohr. Recently, Quintino et al. [Phys. Rev. Lett. 113, 160402 (2014)] and Uola et al. [Phys. Rev. Lett. 113, 160403 (2014)] have investigated the relation between these two distinct non-classical features. They have shown that a set of measurements is not jointly measurable (i.e., incompatible) if and only if they can be used for demonstrating Schrödinger-Einstein-Podolsky-Rosen steering. Themore » concept of steering has been generalized for more general abstract tensor product theories rather than just Hilbert space quantum mechanics. In this article, we discuss that the notion of measurement incompatibility can be extended for general probability theories. Further, we show that the connection between steering and measurement incompatibility holds in a border class of tensor product theories rather than just quantum theory.« less

Water resources of Duval County, Florida

USGS Publications Warehouse

Phelps, G.G.

1994-01-01

The report describes the hydrology and water resources of Duval County, the development of its water supplies, and water use within the county. Also included are descriptions of various natural features of the county (such as topography and geology), an explanation of the hydrologic cycle, and an interpretation of the relationship between them. Ground-water and surface-water resources and principal water-quality features within the county are also discussed. The report is intended to provide the general public with an overview of the water resources Of Duval County, and to increase public awareness of water issues. Information is presented in nontechnical language to enable the general reader to understand facts about water as a part of nature, and the problems associated with its development and use.

General properties of quantum optical systems in a strong field limit

NASA Technical Reports Server (NTRS)

Chumakov, S. M.; Klimov, Andrei B.

1994-01-01

We investigate the dynamics of an arbitrary atomic system (n-level atoms or many n-level atoms) interacting with a resonant quantized mode of an em field. If the initial field state is a coherent state with a large photon number then the system dynamics possesses some general features, independently of the particular structure of the atomic system. Namely, trapping states, factorization of the wave function, collapses and revivals of the atomic energy oscillations are discussed.

General theories and features of interfacial thermal transport

NASA Astrophysics Data System (ADS)

Zhou, Hangbo; Zhang, Gang

2018-03-01

A clear understanding and proper control of interfacial thermal transport is important in nanoscale device. In this review, we first discuss the theoretical methods to handle the interfacial thermal transport problem, such as the macroscopic model, molecular dynamics, lattice dynamics and modern quantum transport theories. Then we discuss various effects that can significantly affect the interfacial thermal transport, such as the formation of chemical bonds at interface, defects and interface roughness, strain and substrates, atomic species and mass ratios, structural orientations. Then importantly, we analyze the role of inelastic scatterings at the interface, and discuss its application in thermal rectifications. Finally, the challenges and promising directions are discussed.

Post-conflict slowing after incongruent stimuli: from general to conflict-specific.

PubMed

Rey-Mermet, Alodie; Meier, Beat

2017-05-01

Encountering a cognitive conflict not only slows current performance, but it can also affect subsequent performance, in particular when the conflict is induced with bivalent stimuli (i.e., stimuli with relevant features for two different tasks) or with incongruent trials (i.e., stimuli with relevant features for two response alternatives). The post-conflict slowing following bivalent stimuli, called "bivalency effect", affects all subsequent stimuli, irrespective of whether the subsequent stimuli share relevant features with the conflict stimuli. To date, it is unknown whether the conflict induced by incongruent stimuli results in a similar post-conflict slowing. To investigate this, we performed six experiments in which participants switched between two tasks. In one task, incongruent stimuli appeared occasionally; in the other task, stimuli shared no feature with the incongruent trials. The results showed an initial performance slowing that affected all tasks after incongruent trials. On further trials, however, the slowing only affected the task sharing features with the conflict stimuli. Therefore, the post-conflict slowing following incongruent stimuli is first general and then becomes conflict-specific across trials. These findings are discussed within current task switching and cognitive control accounts.

Design and Development of "The Reading Biographer": An Application of Function Specific Assessment.

ERIC Educational Resources Information Center

Hanson, Ralph A.; Siegel, Donna Farrell

The general features of function-specific assessment are described and illustrated via a discussion of the design and development of "The Reading Biographer," an instrument for assessing experiences and activities of students (from early childhood through high school) that affect their reading achievement as high school seniors. The…

Cultivating Advanced Technical Writing Skills through a Graduate-Level Course on Writing Research Proposals

ERIC Educational Resources Information Center

McCarthy, Brian D.; Dempsey, Jillian L.

2017-01-01

A graduate-level course focused on original research proposals is introduced to address the uneven preparation in technical writing of new chemistry graduate students. This course focuses on writing original research proposals. The general course structure features extensive group discussions, small-group activities, and regular in-class…

Evaluation of Agricultural Accounting Software. Improved Decision Making. Third Edition.

ERIC Educational Resources Information Center

Lovell, Ashley C., Comp.

Following a discussion of the evaluation criteria for choosing accounting software, this guide contains reviews of 27 accounting software programs that could be used by farm or ranch business managers. The information in the reviews was provided by the software vendors and covers the following points for each software package: general features,…

A Guide to Analysing Tongue Motion from Ultrasound Images

ERIC Educational Resources Information Center

Stone, Maureen

2005-01-01

This paper is meant to be an introduction to and general reference for ultrasound imaging for new and moderately experienced users of the instrument. The paper consists of eight sections. The first explains how ultrasound works, including beam properties, scan types and machine features. The second section discusses image quality, including the…

Line group techniques in description of the structural phase transitions in some superconductors

NASA Technical Reports Server (NTRS)

Meszaros, CS.; Balint, A.; Bankuti, J.

1995-01-01

The main features of the theory of line groups, and their irreducible representations are briefly discussed, as well as the most important applications of them. A new approach in the general symmetry analysis of the modulated systems is presented. It is shown, that the line group formalism could be a very effective tool in the examination of the structural phase transitions in High Temperature SUperconductors. As an example, the material YBa2Cu3O(7-x) is discussed briefly.

An unusual presentation of eosinophilic angiocentric fibrosis.

PubMed

Hardman, Joel; Toon, Christopher; Nirmalananda, Arjuna

2017-12-01

Eosinophilic angiocentric fibrosis (EAF) is a rare, benign condition affecting the respiratory mucosa and is generally characterized by a locally destructive growth. We present a case of a lady with a saddle nose deformity that had for many years been treated as granulomatosis with polyangiitis (GPA), of which saddle nose deformity is a classic feature. At the time of surgery, she was found to have subglottic stenosis another classic feature of GPA, however, histology demonstrated EAF. We discuss the difference between the two conditions and highlight the importance of making the correct diagnosis.

Thermal infrared remote sensing of surface features for renewable resource applications

NASA Technical Reports Server (NTRS)

Welker, J. E.

1981-01-01

The subjects of infrared remote sensing of surface features for renewable resource applications is reviewed with respect to the basic physical concepts involved at the Earth's surface and up through the atmosphere, as well as the historical development of satellite systems which produce such data at increasingly greater spatial resolution. With this general background in hand, the growth of a variety of specific renewable resource applications using the developing thermal infrared technology are discussed, including data from HCMM investigators. Recommendations are made for continued growth in this field of applications.

The crustal tectonics and history of Europa: A structural, morphological, and comparative analysis. M.S. Thesis

NASA Technical Reports Server (NTRS)

Schenk, P. M.

1984-01-01

An evaluation of surface features and structures on the Galilean moon Europa is made using the available high resolution Voyager imagery, low resolution support imaging, and what understanding of ice structure and mechanical behavior science has that is applicable to the problem. A general discussion of the history of Europa studies and the fundamental global morphology is undertaken. The visible lineament and terrain patterns are described, and possible origins discussed. Observations of faulting and block rotation previously described are amplified. A comparison of Europa's structures to terrestrial sea ice and lava lake crust features is also included. Finally, an attempt is made at synthesizing a unified model for the evolution of Europa's crust is presented which is compared with models developed by others.

Computational methods for fracture analysis of heavy-section steel technology (HSST) pressure vessel experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bass, B.R.; Bryan, R.H.; Bryson, J.W.

This paper summarizes the capabilities and applications of the general-purpose and special-purpose computer programs that have been developed for use in fracture mechanics analyses of HSST pressure vessel experiments. Emphasis is placed on the OCA/USA code, which is designed for analysis of pressurized-thermal-shock (PTS) conditions, and on the ORMGEN/ADINA/ORVIRT system which is used for more general analysis. Fundamental features of these programs are discussed, along with applications to pressure vessel experiments.

Computer-aided prognosis on breast cancer with hematoxylin and eosin histopathology images: A review.

PubMed

Chen, Jia-Mei; Li, Yan; Xu, Jun; Gong, Lei; Wang, Lin-Wei; Liu, Wen-Lou; Liu, Juan

2017-03-01

With the advance of digital pathology, image analysis has begun to show its advantages in information analysis of hematoxylin and eosin histopathology images. Generally, histological features in hematoxylin and eosin images are measured to evaluate tumor grade and prognosis for breast cancer. This review summarized recent works in image analysis of hematoxylin and eosin histopathology images for breast cancer prognosis. First, prognostic factors for breast cancer based on hematoxylin and eosin histopathology images were summarized. Then, usual procedures of image analysis for breast cancer prognosis were systematically reviewed, including image acquisition, image preprocessing, image detection and segmentation, and feature extraction. Finally, the prognostic value of image features and image feature-based prognostic models was evaluated. Moreover, we discussed the issues of current analysis, and some directions for future research.

RATFOR user's guide version 2.0

NASA Technical Reports Server (NTRS)

Helmle, L. C.

1985-01-01

This document is a user's guide for RATFOR at Ames Research Center. The main part of the document is a general description of RATFOR, and the appendix is devoted to a machine specific implementation for the Cray X-MP. The general stylistic features of RATFOR are discussed, including the block structure, keywords, source code, format, and the notion of tokens. There is a section on the basic control structures (IF-ELSE, ELSE IF, WHILE, FOR, DO, REPEAT-UNTIL, BREAK, NEXT), and there is a section on the statements that extend FORTRAN's capabilities (DEFINE, MACRO, INCLUDE, STRING). THE appendix discusses everything needed to compile and run a basic job, the preprocessor options, the supported character sets, the generated listings, fatal errors, and program limitations and the differences from standard FORTRAN.

Time-nonlocal kinetic equations, jerk and hyperjerk in plasmas and solar physics

NASA Astrophysics Data System (ADS)

El-Nabulsi, Rami Ahmad

2018-06-01

The simulation and analysis of nonlocal effects in fluids and plasmas is an inherently complicated problem due to the massive breadth of physics required to describe the nonlocal dynamics. This is a multi-physics problem that draws upon various miscellaneous fields, such as electromagnetism and statistical mechanics. In this paper we strive to focus on one narrow but motivating mathematical way: the derivation of nonlocal plasma-fluid equations from a generalized nonlocal Liouville derivative operator motivated from Suykens's nonlocal arguments. The paper aims to provide a guideline toward modeling nonlocal effects occurring in plasma-fluid systems by means of a generalized nonlocal Boltzmann equation. The generalized nonlocal equations of fluid dynamics are derived and their implications in plasma-fluid systems are addressed, discussed and analyzed. Three main topics were discussed: Landau damping in plasma electrodynamics, ideal MHD and solar wind. A number of features were revealed, analyzed and confronted with recent research results and observations.

Electrolysis of lunar soil to produce oxygen and metals

NASA Technical Reports Server (NTRS)

Colson, Russell O.; Haskin, Larry A.; Keller, R.

1991-01-01

The discussion of melt electrolysis consists of three sections. The implications of the chemistry and physics of fluxed and raw melts on melt electrolysis are discussed first. This includes discussion of the factor that influence melt resistivity, melt viscosity, oxygen production efficiency, and the theoretical energy required to produce oxygen. Second, the implications of phase equilibria and solubilities in silicate melts on the selection of materials for container and electrodes are discussed. The implications of proposed container and electrode materials on melt composition and how this effects expected resistivities, viscosities, as outlined in the first section are discussed. Finally, a general discussion of the basic features of both the fluxed and unfluxed melt electrolysis is given, including their advantages and disadvantages and how they compare with alternative processes.

Organizational Development for Thornlea; A Communication Package and Some Results

ERIC Educational Resources Information Center

Croft, John C.

1970-01-01

This case study discusses assumptions and objectives of organizational development (OD) in general, some background of a school which recently participated in a very brief taste of OD, some essential features of the package itself and some results, and some implications. Comments follow by Gilbert D. Moore, State University of New York, Buffalo,…

The Discourse Function of the Greek Future Tense-Form: A Corpus Linguistic Discourse Analysis

ERIC Educational Resources Information Center

Long, Craig M.

2013-01-01

As the Greek verbal system has become the subject of various dissertations and monographs, the future tense-form has been generally overlooked in the discussion. This dissertation seeks to overcome this lacuna by suggesting that the future tense-form functions as a rhetorical feature that expresses the author's expectation of an alternative state…

Trade, Education and the GATS: What's In, What's Out, What's All the Fuss about?

ERIC Educational Resources Information Center

Sauve, Pierre

2002-01-01

Addresses some of the public policy controversies surrounding the treatment of education services under the World Trade Organization's General Agreement on Trade in Services (GATS). Describes the core features of GATS, highlighting how the four modes of supplying services relate to trade in education services and discusses the limited role GATS…

Latin America: A Filmic Approach. Latin American Studies Program, Film Series No. 1.

ERIC Educational Resources Information Center

Campbell, Leon G.; And Others

This document describes a university course designed to provide an historical understanding of Latin America through feature films. The booklet contains an introductory essay on the teaching of a film course on Latin America, a general discussion of strengths and weaknesses of student analyses of films, and nine analyses written by students during…

The Diagnosis and Understanding of Apraxia of Speech: Why Including Neurodegenerative Etiologies May Be Important

ERIC Educational Resources Information Center

Duffy, Joseph R.; Josephs, Keith A.

2012-01-01

Purpose: To discuss apraxia of speech (AOS) as it occurs in neurodegenerative disease (progressive AOS [PAOS]) and how its careful study may contribute to general concepts of AOS and help refine its diagnostic criteria. Method: The article summarizes our current understanding of the clinical features and neuroanatomical and pathologic correlates…

CFD for hypersonic airbreathing aircraft

NASA Technical Reports Server (NTRS)

Kumar, Ajay

1989-01-01

A general discussion is given on the use of advanced computational fluid dynamics (CFD) in analyzing the hypersonic flow field around an airbreathing aircraft. Unique features of the hypersonic flow physics are presented and an assessment is given of the current algorithms in terms of their capability to model hypersonic flows. Several examples of advanced CFD applications are then presented.

Safety and General Considerations for the Use of Antibodies in Infectious Diseases.

PubMed

Hey, Adam Seidelin

2017-01-01

Monocolonal antibodies are valuable potential new tools for meeting unmet needs in treating infectious dieseases and to provide alternatives and supplements to antibiotics in these times of growing resistance. Especially when considering the ability to screen for antibodies reacting to very diverse target antigens and the ability to design and engineer them to work specifically to hit and overcome their strategies, like toxins and their hiding in specific cells to evade the immuneresponse and their special features enabling killing of the infectious agents and or the cells harbouring them. Antibodies are generally very safe and adverse effects of treatments with therapeutic antibodies are usually related to exaggeration of the intended pharmacology. In this chapter general safety considerations for the use of antibodies is reviewed and the general procedures for nonclinical testing to support their clinical development. Special considerations for anti-infective mAb treatments are provided including the special features that makes nonclinical safety programs for anti-infective mAbs much more simple and restricted. However at a cost since only limited information for clinical safety and modeling can be derived from such programs. Then strategies for optimally designing antibodies are discussed including the use of combination of antibodies. Finally ways to facilitate development of more than the currently only three approved mAb based treatments are discussed with a special focus on high costs and high price and how collaboration and new strategies for development in emerging markets can be a driver for this.

Interpretation of temporal features in an unusual X-ray and microwave bursts

NASA Technical Reports Server (NTRS)

Mackinnon, A. L.; Costa, J. E. R.; Kaufmann, P.; Dennis, B. R.

1986-01-01

Observations are briefly discussed of an event in which microwave and hard X-ray emissions were not correlated in the accepted way. Two impulsive peaks of roughly equal intensity were observed at three different microwave frequencies. The hard X-ray peaks accompanying these, however, differ in intensity by almost two orders of magnitude. Various possible interpretations of this burst are discussed, in the context of familiar models of these emissions. The most likely explanation is that the electron spectrum in the first burst has a break at about 350 keV. General implications for interpretation of X-rays and microwaves are discussed.

C++, objected-oriented programming, and astronomical data models

NASA Technical Reports Server (NTRS)

Farris, A.

1992-01-01

Contemporary astronomy is characterized by increasingly complex instruments and observational techniques, higher data collection rates, and large data archives, placing severe stress on software analysis systems. The object-oriented paradigm represents a significant new approach to software design and implementation that holds great promise for dealing with this increased complexity. The basic concepts of this approach will be characterized in contrast to more traditional procedure-oriented approaches. The fundamental features of objected-oriented programming will be discussed from a C++ programming language perspective, using examples familiar to astronomers. This discussion will focus on objects, classes and their relevance to the data type system; the principle of information hiding; and the use of inheritance to implement generalization/specialization relationships. Drawing on the object-oriented approach, features of a new database model to support astronomical data analysis will be presented.

Interface, information, interaction: a narrative review of design and functional requirements for clinical decision support.

PubMed

Miller, Kristen; Mosby, Danielle; Capan, Muge; Kowalski, Rebecca; Ratwani, Raj; Noaiseh, Yaman; Kraft, Rachel; Schwartz, Sanford; Weintraub, William S; Arnold, Ryan

2018-05-01

Provider acceptance and associated patient outcomes are widely discussed in the evaluation of clinical decision support systems (CDSSs), but critical design criteria for tools have generally been overlooked. The objective of this work is to inform electronic health record alert optimization and clinical practice workflow by identifying, compiling, and reporting design recommendations for CDSS to support the efficient, effective, and timely delivery of high-quality care. A narrative review was conducted from 2000 to 2016 in PubMed and The Journal of Human Factors and Ergonomics Society to identify papers that discussed/recommended design features of CDSSs that are associated with the success of these systems. Fourteen papers were included as meeting the criteria and were found to have a total of 42 unique recommendations; 11 were classified as interface features, 10 as information features, and 21 as interaction features. Features are defined and described, providing actionable guidance that can be applied to CDSS development and policy. To our knowledge, no reviews have been completed that discuss/recommend design features of CDSS at this scale, and thus we found that this was important for the body of literature. The recommendations identified in this narrative review will help to optimize design, organization, management, presentation, and utilization of information through presentation, content, and function. The designation of 3 categories (interface, information, and interaction) should be further evaluated to determine the critical importance of the categories. Future work will determine how to prioritize them with limited resources for designers and developers in order to maximize the clinical utility of CDSS. This review will expand the field of knowledge and provide a novel organization structure to identify key recommendations for CDSS.

Global Mean Temperature Timeseries Projections from GCMs: The Implications of Rebasing

NASA Astrophysics Data System (ADS)

Chapman, S. C.; Stainforth, D. A.; Watkins, N. W.

2017-12-01

Global climate models are assessed by comparison with observations through several benchmarks. One highlighted by the InterGovernmental Panel on Climate Change (IPCC) is their ability to reproduce "general features of the global and annual mean surface temperature changes over the historical period" [1,2] and to simulate "a trend in global-mean surface temperature from 1951 to 2012 that agrees with the observed trend" [3]. These aspects of annual mean global mean temperature (GMT) change are presented as one feature demonstrating the relevance of these models for climate projections. Here we consider a formal interpretation of "general features" and discuss the implications of this approach to model assessment and intercomparison, for the interpretation of GCM projections. Following the IPCC, we interpret a major element of "general features" as being the slow timescale response to external forcings. (Shorter timescale behaviour such as the response to volcanic eruptions are also elements of "general features" but are not considered here.) Also following the IPCC, we consider only GMT anomalies. The models have absolute temperatures which range over about 3K so this means their timeseries (and the observations) are rebased. We show that rebasing in combination with general agreement, implies a separation of scales which limits the degree to which sub-global behaviour can feedback on the global response. It also implies a degree of linearity in the GMT slow timescale response. For each individual model these implications only apply over the range of absolute temperatures simulated by the model in historic simulations. Taken together, however, they imply consequences over a wider range of GMTs. [1] IPCC, Fifth Assessment Report, Working Group 1, Technical Summary: Stocker et al. 2013. [2] IPCC, Fifth Assessment Report, Working Group 1, Chapter 9 - "Evaluation of Climate Models": Flato et al. 2013. [3] IPCC, Fifth Assessment Report, Working Group 1, Summary for Policy Makers: IPCC, 2013.

Dementia in the movies: the clinical picture.

PubMed

Gerritsen, Debby L; Kuin, Yolande; Nijboer, Jessika

2014-01-01

Visual media influence the general public's perceptions and attitudes regarding people with mental conditions. This qualitative study investigates the depiction accuracy of dementia's clinical features in motion pictures. Using the search terms 'dementia', 'Alzheimer's disease' and 'senility' movies with release dates between January 2000 and March 2012 were sought on the Internet Movie Database. Based on four selection criteria 23 movies were included. Independently, three researchers watched all movies, scored symptoms, capacities, and behaviors. Scores were discussed and refined during consensus meetings, resulting in a taxonomy of clinical features. Various features are found, most often cognitive symptoms. Behavioral features are also shown - retiring behavior more than agitation - and various emotions, but physical symptoms are rarely depicted. Capacities are infrequently presented and are unrealistic in several of the movies. The clinical picture of dementia portrayed in fictional movies is mild and may be misleading.

Line group techniques in description of the structural phase transitions in some superconductors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meszaros, C.; Bankuti, J.; Balint, A.

1994-12-31

The main features of the theory of line groups, and their irreducible representations are briefly discussed, as well as the most important applications of them. A new approach in the general symmetry analysis of the modulated systems is presented. It is shown, that the line group formalism could be a very effective tool in the examination of the structural phase transitions in High Temperature Superconductors. As an example, the material YBa{sub 2}Cu{sub 3}O{sub 7-x} is discussed briefly.

Space engine safety system

NASA Technical Reports Server (NTRS)

Maul, William A.; Meyer, Claudia M.

1991-01-01

A rocket engine safety system was designed to initiate control procedures to minimize damage to the engine or vehicle or test stand in the event of an engine failure. The features and the implementation issues associated with rocket engine safety systems are discussed, as well as the specific concerns of safety systems applied to a space-based engine and long duration space missions. Examples of safety system features and architectures are given, based on recent safety monitoring investigations conducted for the Space Shuttle Main Engine and for future liquid rocket engines. Also, the general design and implementation process for rocket engine safety systems is presented.

Scale invariance in biophysics

NASA Astrophysics Data System (ADS)

Stanley, H. Eugene

2000-06-01

In this general talk, we offer an overview of some problems of interest to biophysicists, medical physicists, and econophysicists. These include DNA sequences, brain plaques in Alzheimer patients, heartbeat intervals, and time series giving price fluctuations in economics. These problems have the common feature that they exhibit features that appear to be scale invariant. Particularly vexing is the problem that some of these scale invariant phenomena are not stationary-their statistical properties vary from one time interval to the next or form one position to the next. We will discuss methods, such as wavelet methods and multifractal methods, to cope with these problems. .

CHARGED PARTICLE MULTIPLICITIES IN ULTRA-RELATIVISTIC AU+AU AND CU+CU COLLISIONS

NASA Astrophysics Data System (ADS)

Back, B. B.; Alver, B.; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Busza, W.; Carroll, A.; Chai, Z.; Chetluru, V.; Decowski, M. P.; Garcia, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Halliwell, C.; Hamblen, J.; Harnarine, I.; Hauer, M.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Holynski, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Khan, N.; Kulinich, P.; Kuo, C. M.; Li, W.; Lin, W. T.; Loizides, C.; Manly, S.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Reed, C.; Richardson, E.; Roland, C.; Roland, G.; Sagerer, J.; Seals, H.; Sedykh, I.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Szostak, A.; Tonjes, M. B.; Trzupek, A.; Vale, C.; Vannieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Walters, P.; Wenger, E.; Willhelm, D.; Wolfs, F. L. H.; Wosiek, B.; Wozniak, K.; Wyngaardt, S.; Wyslouch, B.

The PHOBOS collaboration has carried out a systematic study of charged particle multiplicities in Cu+Cu and Au+Au collisions at the Relativistic Heavy-Ion Collider (RHIC) at Brookhaven National Laboratory. A unique feature of the PHOBOS detector is its ability to measure charged particles over a very wide angular range from 0.5° to 179.5° corresponding to |η| <5.4. The general features of the charged particle multiplicity distributions as a function of pseudo-rapidity, collision energy and centrality, as well as system size, are discussed.

Influencing Attitudes Toward Near and Distant Objects

PubMed Central

Fujita, Kentaro; Eyal, Tal; Chaiken, Shelly; Trope, Yaacov; Liberman, Nira

2008-01-01

It is argued that the temporal distance of attitude objects systematically changes how the object is mentally represented, and thus influences the strength of particular persuasive appeals. Three experiments tested the hypothesis that people preferentially attend to arguments that highlight primary, abstract (high-level) vs. incidental, concrete (low-level) features when attitude objects are temporally distant vs. near. Results suggested that when attitude objects are temporally distant vs. near, arguments emphasizing primary vs. secondary features (Study 1), desirability vs. feasibility features (Study 2), and general classes vs. specific cases are more persuasive (Study 3). The relation of construal theory to dual process theories of persuasion and persuasion phenomena, such as personal relevance effects and functional matching effects, are discussed. PMID:19884971

The geography and geology of Alaska; a summary of existing knowledge, with a section on climate, and a topographic map and description thereof

USGS Publications Warehouse

Brooks, A.H.; Abbe, Cleveland; Goode, R.U.

1906-01-01

It is the writer's purpose to describe in nontechnical language the larger geographic features and discuss their relation as far as the data available will permit. In the treatment of the geology, however, less effort will be made to make the matter acceptable to the lay reader. It is hoped, however, that a brief summary of the salient features of the geologic history' may be not without interest to the general public. If this paper serves in some measure to dispel the popular fallacies regarding Alaska and to disseminate more accurate knowledge of its geographic and geologic features, the purpose of its publication will be accomplished.

Airway Management in a Patient with Wolf-Hirschhorn Syndrome.

PubMed

Gamble, John F; Kurian, Dinesh J; Udani, Andrea G; Greene, Nathaniel H

2016-01-01

We present a case of a 3-month-old female with Wolf-Hirschhorn syndrome (WHS) undergoing general anesthesia for laparoscopic gastrostomy tube placement with a focus on airway management. WHS is a rare 4p microdeletion syndrome resulting in multiple congenital abnormalities, including craniofacial deformities. Microcephaly, micrognathia, and glossoptosis are common features in WHS patients and risk factors for a pediatric airway that is potentially difficult to intubate. We discuss anesthesia strategies for airway preparation and management in a WHS patient requiring general anesthesia with endotracheal intubation.

Airway Management in a Patient with Wolf-Hirschhorn Syndrome

PubMed Central

Udani, Andrea G.

2016-01-01

We present a case of a 3-month-old female with Wolf-Hirschhorn syndrome (WHS) undergoing general anesthesia for laparoscopic gastrostomy tube placement with a focus on airway management. WHS is a rare 4p microdeletion syndrome resulting in multiple congenital abnormalities, including craniofacial deformities. Microcephaly, micrognathia, and glossoptosis are common features in WHS patients and risk factors for a pediatric airway that is potentially difficult to intubate. We discuss anesthesia strategies for airway preparation and management in a WHS patient requiring general anesthesia with endotracheal intubation. PMID:27752382

Basalt models for the Mars penetrator mission: Geology of the Amboy Lava Field, California

NASA Technical Reports Server (NTRS)

Greeley, R.; Bunch, T. E.

1976-01-01

Amboy lava field (San Bernardino County, California) is a Holocene basalt flow selected as a test site for potential Mars Penetrators. A discussion is presented of (1) the general relations of basalt flow features and textures to styles of eruptions on earth, (2) the types of basalt flows likely to be encountered on Mars and the rationale for selection of the Amboy lava field as a test site, (3) the general geology of the Amboy lava field, and (4) detailed descriptions of the target sites at Amboy lava field.

The Role of Water Chemistry in Marine Aquarium Design: A Model System for a General Chemistry Class

ERIC Educational Resources Information Center

Keaffaber, Jeffrey J.; Palma, Ramiro; Williams, Kathryn R.

2008-01-01

Water chemistry is central to aquarium design, and it provides many potential applications for discussion in undergraduate chemistry and engineering courses. Marine aquaria and their life support systems feature many chemical processes. A life support system consists of the entire recirculation system, as well as the habitat tank and all ancillary…

Gaussian black holes in Rastall gravity

NASA Astrophysics Data System (ADS)

Spallucci, Euro; Smailagic, Anais

In this short note we present the solution of Rastall gravity equations sourced by a Gaussian matter distribution. We find that the black hole metric shares all the common features of other regular, General Relativity BH solutions discussed in the literature: there is no curvature singularity and the Hawking radiation leaves a remnant at zero temperature in the form of a massive ordinary particle.

Lessons learned in using IPE model for IPEEE study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guey, C.

1995-12-31

This paper summarizes lessons learned in applying the plant model developed in the Individual Plant Examination (IPE) to the IPE for External Events (IPEEE). Both core damage frequency and containment performance features are addressed. The IPE model applications are discussed for internal fires, hurricanes, and tornadoes. Areas in which the IPE model may be improved and general findings are described.

The quadrupole ionosphere

NASA Technical Reports Server (NTRS)

Rishbeth, H.

1986-01-01

The principal features that might exist in the terrestrial paleoionosphere, if the geomagnetic field were to assume a quadrupole form during a polarity reversal are discussed. Complicated phenomena would be expected to occur at magnetic equators and magnetospherically-driven plasma convection might occur at latitudes where the magnetic field is steeply inclined. The influence of magnetic field strength on ionospheric structure is considered in general terms.

Patterns of Sophistication and Naivety: Some Features of Anthropological Approaches to the Study of Education. Occasional Paper No. 22.

ERIC Educational Resources Information Center

Erickson, Frederick

The limits and boundaries of anthropology are briefly discussed, along with a general description of lay attitudes towards the field. A research case is given to illustrate the way in which anthropological study methods can contribute to educational research. Noted among these contributions is an informed distrust that anthropologists exhibit…

Getting Personal--What Does It Mean? A Critical Discussion of the Personal Dimension of Thesis Supervision in Higher Education

ERIC Educational Resources Information Center

Bengtsen, Soren S. E.

2011-01-01

The argument of the article is that contemporary research into thesis supervision overlooks important didactical features of the supervisory dialogue because of its focus on general pedagogical categories. Entailing this argument I suggest that the personal dimension should be seen not only as a means to enhanced communication between supervisor…

Structural optimization via a design space hierarchy

NASA Technical Reports Server (NTRS)

Vanderplaats, G. N.

1976-01-01

Mathematical programming techniques provide a general approach to automated structural design. An iterative method is proposed in which design is treated as a hierarchy of subproblems, one being locally constrained and the other being locally unconstrained. It is assumed that the design space is locally convex in the case of good initial designs and that the objective and constraint functions are continuous, with continuous first derivatives. A general design algorithm is outlined for finding a move direction which will decrease the value of the objective function while maintaining a feasible design. The case of one-dimensional search in a two-variable design space is discussed. Possible applications are discussed. A major feature of the proposed algorithm is its application to problems which are inherently ill-conditioned, such as design of structures for optimum geometry.

Guillian Barré syndrome--recent advances.

PubMed

Vedanarayanan, V V; Chaudhry, V

2000-09-01

Guillian Barré Syndrome (GBS) is an acquired disease of the peripheral nerves that is characterized clinically by rapidly progressing paralysis, areflexia, and albumino-cytological dissociation. It affects both genders, involves people of all ages, is reported worldwide, and in the post-polio era, it is the most common cause of an acute generalized paralysis. The clinical features are distinct and a history and an examination generally lead to a high suspicion of the diagnosis that can then be confirmed by supportive laboratory tests and electrodiagnostic studies. This review discusses the recent advances in understanding of the different variants of GBS such as acute inflammatory demyelinating polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), acute motor sensory axonal neuropathy (AMSAN), and the Fisher syndrome. The clinical, electrodiagnostic criteria, immunopathogenesis, and management of GBS and its variants are discussed.

The Design of a High Performance Earth Imagery and Raster Data Management and Processing Platform

NASA Astrophysics Data System (ADS)

Xie, Qingyun

2016-06-01

This paper summarizes the general requirements and specific characteristics of both geospatial raster database management system and raster data processing platform from a domain-specific perspective as well as from a computing point of view. It also discusses the need of tight integration between the database system and the processing system. These requirements resulted in Oracle Spatial GeoRaster, a global scale and high performance earth imagery and raster data management and processing platform. The rationale, design, implementation, and benefits of Oracle Spatial GeoRaster are described. Basically, as a database management system, GeoRaster defines an integrated raster data model, supports image compression, data manipulation, general and spatial indices, content and context based queries and updates, versioning, concurrency, security, replication, standby, backup and recovery, multitenancy, and ETL. It provides high scalability using computer and storage clustering. As a raster data processing platform, GeoRaster provides basic operations, image processing, raster analytics, and data distribution featuring high performance computing (HPC). Specifically, HPC features include locality computing, concurrent processing, parallel processing, and in-memory computing. In addition, the APIs and the plug-in architecture are discussed.

The Development of Web-based Graphical User Interface for Unified Modeling Data with Multi (Correlated) Responses

NASA Astrophysics Data System (ADS)

Made Tirta, I.; Anggraeni, Dian

2018-04-01

Statistical models have been developed rapidly into various directions to accommodate various types of data. Data collected from longitudinal, repeated measured, clustered data (either continuous, binary, count, or ordinal), are more likely to be correlated. Therefore statistical model for independent responses, such as Generalized Linear Model (GLM), Generalized Additive Model (GAM) are not appropriate. There are several models available to apply for correlated responses including GEEs (Generalized Estimating Equations), for marginal model and various mixed effect model such as GLMM (Generalized Linear Mixed Models) and HGLM (Hierarchical Generalized Linear Models) for subject spesific models. These models are available on free open source software R, but they can only be accessed through command line interface (using scrit). On the othe hand, most practical researchers very much rely on menu based or Graphical User Interface (GUI). We develop, using Shiny framework, standard pull down menu Web-GUI that unifies most models for correlated responses. The Web-GUI has accomodated almost all needed features. It enables users to do and compare various modeling for repeated measure data (GEE, GLMM, HGLM, GEE for nominal responses) much more easily trough online menus. This paper discusses the features of the Web-GUI and illustrates the use of them. In General we find that GEE, GLMM, HGLM gave very closed results.

Addressing narcissistic personality features in the context of medical care: integrating diverse perspectives to inform clinical practice.

PubMed

Magidson, J F; Collado-Rodriguez, A; Madan, A; Perez-Camoirano, N A; Galloway, S K; Borckardt, J J; Campbell, W K; Miller, J D

2012-04-01

Narcissistic personality disorder (NPD) is characterized by an unrealistic need for admiration, lack of empathy toward others, and feelings of superiority. NPD presents a unique and significant challenge in clinical practice, particularly in medical settings with limited provider contact time, as health professionals treat individuals who often require excessive admiration and have competing treatment needs. This practice review highlights real case examples across three distinct medically oriented clinical settings (inpatient and outpatient behavioral medicine and a Level I trauma center) to demonstrate the difficult and compromising situations that providers face when treating patients with general medical conditions and comorbid narcissistic personality features. The main goal of this article is to discuss the various challenges and obstacles associated with these cases in medical settings and discuss some strategies that may prove successful. A second goal is to bridge diverse conceptualizations of narcissism/NPD through the discussion of theoretical and empirical perspectives that can inform understanding of the clinical examples. Despite differing perspectives regarding the underlying motivation of narcissistic behavior, this practice review highlights that these paradigms can be integrated when sharing the same ultimate goal: to improve delivery of care across medically oriented clinical settings for patients with narcissistic features.

Gas and isotope chemistry of thermal features in Yellowstone National Park, Wyoming

USGS Publications Warehouse

Bergfeld, D.; Lowenstern, Jacob B.; Hunt, Andrew G.; Shanks, W.C. Pat; Evans, William

2011-01-01

This report presents 130 gas analyses and 31 related water analyses on samples collected from thermal features at Yellowstone between 2003 and 2009. An overview of previous studies of gas emissions at Yellowstone is also given. The analytical results from the present study include bulk chemistry of gases and waters and isotope values for water and steam (delta18O, dealtaD), carbon dioxide (delta13C only), methane (delta13C only), helium, neon, and argon. We include appendixes containing photos of sample sites, geographic information system (GIS) files including shape and kml formats, and analytical results in spreadsheets. In addition, we provide a lengthy discussion of previous work on gas chemistry at Yellowstone and a general discussion of the implications of our results. We demonstrate that gases collected from different thermal areas often have distinct chemical signatures, and that differences across the thermal areas are not a simple function of surface temperatures or the type of feature. Instead, gas chemistry and isotopic composition are linked to subsurface lithologies and varying contributions from magmatic, crustal, and meteoric sources.

Renewal processes based on generalized Mittag-Leffler waiting times

NASA Astrophysics Data System (ADS)

Cahoy, Dexter O.; Polito, Federico

2013-03-01

The fractional Poisson process has recently attracted experts from several fields of study. Its natural generalization of the ordinary Poisson process made the model more appealing for real-world applications. In this paper, we generalized the standard and fractional Poisson processes through the waiting time distribution, and showed their relations to an integral operator with a generalized Mittag-Leffler function in the kernel. The waiting times of the proposed renewal processes have the generalized Mittag-Leffler and stretched-squashed Mittag-Leffler distributions. Note that the generalizations naturally provide greater flexibility in modeling real-life renewal processes. Algorithms to simulate sample paths and to estimate the model parameters are derived. Note also that these procedures are necessary to make these models more usable in practice. State probabilities and other qualitative or quantitative features of the models are also discussed.

Evaluation of a web based informatics system with data mining tools for predicting outcomes with quantitative imaging features in stroke rehabilitation clinical trials

NASA Astrophysics Data System (ADS)

Wang, Ximing; Kim, Bokkyu; Park, Ji Hoon; Wang, Erik; Forsyth, Sydney; Lim, Cody; Ravi, Ragini; Karibyan, Sarkis; Sanchez, Alexander; Liu, Brent

2017-03-01

Quantitative imaging biomarkers are used widely in clinical trials for tracking and evaluation of medical interventions. Previously, we have presented a web based informatics system utilizing quantitative imaging features for predicting outcomes in stroke rehabilitation clinical trials. The system integrates imaging features extraction tools and a web-based statistical analysis tool. The tools include a generalized linear mixed model(GLMM) that can investigate potential significance and correlation based on features extracted from clinical data and quantitative biomarkers. The imaging features extraction tools allow the user to collect imaging features and the GLMM module allows the user to select clinical data and imaging features such as stroke lesion characteristics from the database as regressors and regressands. This paper discusses the application scenario and evaluation results of the system in a stroke rehabilitation clinical trial. The system was utilized to manage clinical data and extract imaging biomarkers including stroke lesion volume, location and ventricle/brain ratio. The GLMM module was validated and the efficiency of data analysis was also evaluated.

A new six-degree-of-freedom force-reflecting hand controller for space telerobotics

NASA Technical Reports Server (NTRS)

Mcaffee, Douglas; Snow, Edward; Townsend, William; Robinson, Lee; Hanson, Joe

1990-01-01

A new 6 degree of freedom universal Force Reflecting Hand Controller (FRHC) was designed for use as the man-machine interface in teleoperated and telerobotic flight systems. The features of this new design include highly intuitive operation, excellent kinesthetic feedback, high fidelity force/torque feedback, a kinematically simple structure, mechanically decoupled motion in all 6 DOF, good back-drivability, and zero backlash. In addition, the new design has a much larger work envelope, smaller stowage volume, greater stiffness and responsiveness, and better overlap of the human operator's range of motion than do previous designs. The utility and basic operation of a new, flight prototype FRHC called the Model X is briefly discussed. The design heritage, general design goals, and design implementation of this advanced new generation of FRHCs are presented, followed by a discussion of basic features and the results of initial testing.

Antisocial features and "faking bad": A critical note.

PubMed

Niesten, Isabella J M; Nentjes, Lieke; Merckelbach, Harald; Bernstein, David P

2015-01-01

We critically review the literature on antisocial personality features and symptom fabrication (i.e., faking bad; e.g., malingering). A widespread assumption is that these constructs are intimately related. Some studies have, indeed, found that antisocial individuals score higher on instruments detecting faking bad, but others have been unable to replicate this pattern. In addition, studies exploring whether antisocial individuals are especially talented in faking bad have generally come up with null results. The notion of an intrinsic link between antisocial features and faking bad is difficult to test and research in this domain is sensitive to selection bias. We argue that research on faking bad would profit from further theoretical articulation. One topic that deserves scrutiny is how antisocial features affect the cognitive dissonance typically induced by faking bad. We illustrate our points with preliminary data and discuss their implications. Copyright © 2015 Elsevier Ltd. All rights reserved.

An examination of generalized anxiety disorder and dysthymia utilizing the Rorschach inkblot method.

PubMed

Slavin-Mulford, Jenelle; Clements, Alyssa; Hilsenroth, Mark; Charnas, Jocelyn; Zodan, Jennifer

2016-06-30

This study examined transdiagnostic features of generalized anxiety disorder (GAD) and dysthymia in an outpatient clinical sample. Fifteen patients who met DSM-IV criteria for GAD and twenty-one patients who met DSM-IV criteria for dysthymia but who did not have comorbid anxiety disorder were evaluated utilizing the Rorschach. Salient clinical variables were then compared. Results showed that patients with GAD scored significantly higher on variables related to cognitive agitation and a desire/need for external soothing. In addition, there was a trend for patients with GAD to produce higher scores on a measure of ruminative focus on negative aspects of the self. Thus, not surprisingly, GAD patients' experienced more distress than the dysthymic patients. The implications of these findings are discussed with regards to better understanding the shared and distinct features of GAD and dysthymia. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Identifying Key Features of Effective Active Learning: The Effects of Writing and Peer Discussion

PubMed Central

Pangle, Wiline M.; Wyatt, Kevin H.; Powell, Karli N.; Sherwood, Rachel E.

2014-01-01

We investigated some of the key features of effective active learning by comparing the outcomes of three different methods of implementing active-learning exercises in a majors introductory biology course. Students completed activities in one of three treatments: discussion, writing, and discussion + writing. Treatments were rotated weekly between three sections taught by three different instructors in a full factorial design. The data set was analyzed by generalized linear mixed-effect models with three independent variables: student aptitude, treatment, and instructor, and three dependent (assessment) variables: change in score on pre- and postactivity clicker questions, and coding scores on in-class writing and exam essays. All independent variables had significant effects on student performance for at least one of the dependent variables. Students with higher aptitude scored higher on all assessments. Student scores were higher on exam essay questions when the activity was implemented with a writing component compared with peer discussion only. There was a significant effect of instructor, with instructors showing different degrees of effectiveness with active-learning techniques. We suggest that individual writing should be implemented as part of active learning whenever possible and that instructors may need training and practice to become effective with active learning. PMID:25185230

The Education Challenges Facing Small Nation States in the Increasingly Competitive Global Economy of the Twenty-First Century

ERIC Educational Resources Information Center

Bacchus, Mohammed Kazim

2008-01-01

Publication of this piece is intended as a tribute to the late Professor M. Kazim Bacchus who passed away in March 2007. The paper provides a general discussion concerning the social and educational challenges faced by small nation states in an age characterised by globalisation. The analysis first identifies some of the basic features of small…

Zwischen Gesetz und Fall. Mutmassungen uber Typologien als Padagogische Wissensform (Between General Law and the Individual Case. Conjectures Concerning Typologies as a Form of Pedagogical Knowledge).

ERIC Educational Resources Information Center

Herzog, Walter

2003-01-01

Considers the mediation between scientific knowledge and practical action as a crucial feature of professional teaching. Investigates the assumption that typologies represent a form of knowledge which can bridge the gap between theory and practice. Differentiates between two forms of typological thinking and discusses reservations concerning…

Using elaborative interrogation to induce characteristics of polar and nonpolar solvents from animations of their molecular structures

NASA Astrophysics Data System (ADS)

Ems-Wilson, Janice

This study concerned (a) how general chemistry students learn to classify solvent polarity from animated molecules, (b) whether peer interaction increases the number of correct classifications, and (c) whether language, academic ability, logical thinking ability, or prior knowledge interact with rate of learning or posttest performance. Two types of interaction were compared, group discussion and elaborative interrogation. The study rested on three assumptions: (a) animated molecules are appropriate for learning the concept of solvent polarity, (b) question stems and a guided interrogation enhance learning of a visual concept, (c) general chemistry students can induce the concept of solvent polarity from animated molecules when no guiding cues, either visual or verbal, are given. After a review of molecular geometry and bonding theories, students were presented with four trials of ten animated molecular structures. Ten three-to-five minute discussions were distributed among the four trials. Prior to the trials the experimental group received a 45-minute training session on elaborative interrogation; the topic was what happens on the molecular level when a carbonated beverage is opened. The control group received a 45-minute expository lecture on the same carbonated beverage topic. Participants were given a four-part posttest immediately following the trials. Results of the study suggest that most students tend to classify the solvent polarity of animated molecules based on certain structural features using a prototype or feature-frequency categorization strategy. Elaborative interrogation did not show a significant effect on the rate of learning or on the performance of learners on posttest measures of recall and comprehension. The experimental group noted a significantly greater number and range of types of features, and offered higher quality generalizations and explanations of their polarity classification procedure. Finally, the results implied that learning from animations depends more on prior knowledge of relevant concepts than on academic ability, logical thinking ability, or preferred language. Although some benefits may arise from accompanying computer animation with an interactive discussion, additional visual and verbal, cueing may be necessary for optimal outcomes.

EEG-based workload estimation across affective contexts

PubMed Central

Mühl, Christian; Jeunet, Camille; Lotte, Fabien

2014-01-01

Workload estimation from electroencephalographic signals (EEG) offers a highly sensitive tool to adapt the human–computer interaction to the user state. To create systems that reliably work in the complexity of the real world, a robustness against contextual changes (e.g., mood), has to be achieved. To study the resilience of state-of-the-art EEG-based workload classification against stress we devise a novel experimental protocol, in which we manipulated the affective context (stressful/non-stressful) while the participant solved a task with two workload levels. We recorded self-ratings, behavior, and physiology from 24 participants to validate the protocol. We test the capability of different, subject-specific workload classifiers using either frequency-domain, time-domain, or both feature varieties to generalize across contexts. We show that the classifiers are able to transfer between affective contexts, though performance suffers independent of the used feature domain. However, cross-context training is a simple and powerful remedy allowing the extraction of features in all studied feature varieties that are more resilient to task-unrelated variations in signal characteristics. Especially for frequency-domain features, across-context training is leading to a performance comparable to within-context training and testing. We discuss the significance of the result for neurophysiology-based workload detection in particular and for the construction of reliable passive brain–computer interfaces in general. PMID:24971046

An investigation of the psychological characteristics of stalkers: empathy, problem-solving, attachment and borderline personality features.

PubMed

Lewis, S F; Fremouw, W J; Del Ben, K; Farr, C

2001-01-01

This study examined the psychological characteristics of a sample of self-reported stalkers in comparison with a control group, on measures of empathy, problem-solving skills, attachment, and borderline personality features. Stalkers were identified by their endorsement of specific behavioral items, consistent with a widely adopted definition of stalking, denoting behaviors that: (a) are repeatedly directed toward an identified target; (b) are intrusive and unwanted; and (c) evoke fear in the victim. Stalkers scored significantly higher than controls on measures of insecure attachment and borderline personality features, suggesting that the stalking group demonstrates a general pattern of inadequate interpersonal attachment, has limited abilities to form and maintain appropriate relationships, is emotionally labile and unstable, and experiences ambivalence regarding their interpersonal relationships. Treatment implications are discussed herein.

The implications of rebasing global mean temperature timeseries for GCM based climate projections

NASA Astrophysics Data System (ADS)

Stainforth, David; Chapman, Sandra; Watkins, Nicholas

2017-04-01

Global climate and earth system models are assessed by comparison with observations through a number of metrics. The InterGovernmental Panel on Climate Change (IPCC) highlights in particular their ability to reproduce "general features of the global and annual mean surface temperature changes over the historical period" [1,2] and to simulate "a trend in global-mean surface temperature from 1951 to 2012 that agrees with the observed trend" [3]. This focus on annual mean global mean temperature (hereafter GMT) change is presented as an important element in demonstrating the relevance of these models for climate projections. Any new model or new model version whose historic simulations fail to reproduce the "general features " and 20th century trends is likely therefore to undergo further tuning. Thus this focus could have implications for model development. Here we consider a formal interpretation of "general features" and discuss the implications of this approach to model assessment and intercomparison, for the interpretation of GCM projections. Following the IPCC, we interpret a major element of "general features" as being the slow timescale response to external forcings. (Shorter timescale behaviour such as the response to volcanic eruptions are also elements of "general features" but are not considered here.) Also following the IPCC, we consider only GMT anomalies i.e. changes with respect to some period. Since the models have absolute temperatures which range over about 3K (roughly observed GMT +/- 1.5K) this means their timeseries (and the observations) are rebased. We present timeseries of the slow timescale response of the CMIP5 models rebased to late-20th century temperatures and to mid-19th century temperatures. We provide a mathematical interpretation of this approach to model assessment and discuss two consequences. First is a separation of scales which limits the degree to which sub-global behaviour can feedback on the global response. Second, is an implication of linearity in the GMT response (to the extent that the slow-timescale response of the historic simulations is consistent with observations, and given their uncertainties). For each individual model these consequences only apply over the range of absolute temperatures simulated by the model in historic simulations. Taken together, however, they imply consequences over a much wider range of GMTs. The analysis suggests that this aspect of model evaluation risks providing a model development pressure which acts against a wide exploration of physically plausible responses; in particular against an exploration of potentially globally significant nonlinear responses and feedbacks. [1] IPCC, Fifth Assessment Report, Working Group 1, Technical Summary: Stocker et al. 2013. [2] IPCC, Fifth Assessment Report, Working Group 1, Chapter 9 - "Evaluation of Climate Models": Flato et al. 2013. [3] IPCC, Fifth Assessment Report, Working Group 1, Summary for Policy Makers: IPCC, 2013.

Observational signatures of spherically-symmetric black hole spacetimes

NASA Astrophysics Data System (ADS)

De Laurentis, Mariafelicia; Younsi, Ziri; Porth, Oliver; Mizuno, Yosuke; Fromm, Christian; Rezzolla, Luciano; Olivares, Hector

2017-12-01

A binary system composed of a supermassive black hole and a pulsar orbiting around it is studied. The motivation for this study arises from the fact that pulsar timing observations have proven to be a powerful tool in identifying physical features of the orbiting companion. In this study, taking into account a general spherically-symmetric metric, we present analytic calculations of the geodesic motion, and the possible deviations with respect to the standard Schwarzschild case of General Relativity. In particular, the advance at periastron is studied with the aim of identifying corrections to General Relativity. A discussion of the motion of a pulsar very close the supermassive central black hole in our Galaxy (Sgr A*) is reported.

Computing group cardinality constraint solutions for logistic regression problems.

PubMed

Zhang, Yong; Kwon, Dongjin; Pohl, Kilian M

2017-01-01

We derive an algorithm to directly solve logistic regression based on cardinality constraint, group sparsity and use it to classify intra-subject MRI sequences (e.g. cine MRIs) of healthy from diseased subjects. Group cardinality constraint models are often applied to medical images in order to avoid overfitting of the classifier to the training data. Solutions within these models are generally determined by relaxing the cardinality constraint to a weighted feature selection scheme. However, these solutions relate to the original sparse problem only under specific assumptions, which generally do not hold for medical image applications. In addition, inferring clinical meaning from features weighted by a classifier is an ongoing topic of discussion. Avoiding weighing features, we propose to directly solve the group cardinality constraint logistic regression problem by generalizing the Penalty Decomposition method. To do so, we assume that an intra-subject series of images represents repeated samples of the same disease patterns. We model this assumption by combining series of measurements created by a feature across time into a single group. Our algorithm then derives a solution within that model by decoupling the minimization of the logistic regression function from enforcing the group sparsity constraint. The minimum to the smooth and convex logistic regression problem is determined via gradient descent while we derive a closed form solution for finding a sparse approximation of that minimum. We apply our method to cine MRI of 38 healthy controls and 44 adult patients that received reconstructive surgery of Tetralogy of Fallot (TOF) during infancy. Our method correctly identifies regions impacted by TOF and generally obtains statistically significant higher classification accuracy than alternative solutions to this model, i.e., ones relaxing group cardinality constraints. Copyright © 2016 Elsevier B.V. All rights reserved.

Archaeal DNA replication.

PubMed

Kelman, Lori M; Kelman, Zvi

2014-01-01

DNA replication is essential for all life forms. Although the process is fundamentally conserved in the three domains of life, bioinformatic, biochemical, structural, and genetic studies have demonstrated that the process and the proteins involved in archaeal DNA replication are more similar to those in eukaryal DNA replication than in bacterial DNA replication, but have some archaeal-specific features. The archaeal replication system, however, is not monolithic, and there are some differences in the replication process between different species. In this review, the current knowledge of the mechanisms governing DNA replication in Archaea is summarized. The general features of the replication process as well as some of the differences are discussed.

Observations on Rotating Cavitation and Cavitation Surge from the Development of the Fastrac Engine Turbopump

NASA Technical Reports Server (NTRS)

Zoladz, Thomas F.

2000-01-01

Observations regarding rotating cavitation and cavitation surge experienced during the development of the Fastrac engine turbopump are discussed. Detailed observations acquired from the analysis of both water flow and liquid oxygen test data are offered in this paper. Scaling and general comparison of rotating cavitation between water flow and liquid oxygen testing are discussed. Complex data features linking the localized rotating cavitation mechanism of the inducer to system surge components are described in detail. Finally a description of a lumped-parameter hydraulic system model developed to better understand observed data is given.

Overview of Rotating Cavitation and Cavitation Surge in the Fastrac Engine LOX Turbopump

NASA Technical Reports Server (NTRS)

Zoladz, Thomas; Turner, Jim (Technical Monitor)

2001-01-01

Observations regarding rotating cavitation and cavitation surge experienced during the development of the Fastrac 60 Klbf engine turbopump are discussed. Detailed observations from the analysis of both water flow and liquid oxygen test data are offered. Scaling and general comparison of rotating cavitation between water flow and liquid oxygen testing are discussed. Complex data features linking the localized rotating cavitation mechanism of the inducer to system surge components are described in detail. Finally a description of a simple lumped-parameter hydraulic system model developed to better understand observed data is given.

Attention in the processing of complex visual displays: detecting features and their combinations.

PubMed

Farell, B

1984-02-01

The distinction between operations in visual processing that are parallel and preattentive and those that are serial and attentional receives both theoretical and empirical support. According to Treisman's feature-integration theory, independent features are available preattentively, but attention is required to veridically combine features into objects. Certain evidence supporting this theory is consistent with a different interpretation, which was tested in four experiments. The first experiment compared the detection of features and feature combinations while eliminating a factor that confounded earlier comparisons. The resulting priority of access to combinatorial information suggests that features and nonlocal combinations of features are not connected solely by a bottom-up hierarchical convergence. Causes of the disparity between the results of Experiment 1 and the results of previous research were investigated in three subsequent experiments. The results showed that of the two confounded factors, it was the difference in the mapping of alternatives onto responses, not the differing attentional demands of features and objects, that underlaid the results of the previous research. The present results are thus counterexamples to the feature-integration theory. Aspects of this theory are shown to be subsumed by more general principles, which are discussed in terms of attentional processes in the detection of features, objects, and stimulus alternatives.

Sparse filtering with the generalized lp/lq norm and its applications to the condition monitoring of rotating machinery

NASA Astrophysics Data System (ADS)

Jia, Xiaodong; Zhao, Ming; Di, Yuan; Li, Pin; Lee, Jay

2018-03-01

Sparsity is becoming a more and more important topic in the area of machine learning and signal processing recently. One big family of sparse measures in current literature is the generalized lp /lq norm, which is scale invariant and is widely regarded as normalized lp norm. However, the characteristics of the generalized lp /lq norm are still less discussed and its application to the condition monitoring of rotating devices has been still unexplored. In this study, we firstly discuss the characteristics of the generalized lp /lq norm for sparse optimization and then propose a method of sparse filtering with the generalized lp /lq norm for the purpose of impulsive signature enhancement. Further driven by the trend of industrial big data and the need of reducing maintenance cost for industrial equipment, the proposed sparse filter is customized for vibration signal processing and also implemented on bearing and gearbox for the purpose of condition monitoring. Based on the results from the industrial implementations in this paper, the proposed method has been found to be a promising tool for impulsive feature enhancement, and the superiority of the proposed method over previous methods is also demonstrated.

Generalized Processing Tree Models: Jointly Modeling Discrete and Continuous Variables.

PubMed

Heck, Daniel W; Erdfelder, Edgar; Kieslich, Pascal J

2018-05-24

Multinomial processing tree models assume that discrete cognitive states determine observed response frequencies. Generalized processing tree (GPT) models extend this conceptual framework to continuous variables such as response times, process-tracing measures, or neurophysiological variables. GPT models assume finite-mixture distributions, with weights determined by a processing tree structure, and continuous components modeled by parameterized distributions such as Gaussians with separate or shared parameters across states. We discuss identifiability, parameter estimation, model testing, a modeling syntax, and the improved precision of GPT estimates. Finally, a GPT version of the feature comparison model of semantic categorization is applied to computer-mouse trajectories.

Seeking instructional specificity: An example from analogical instruction

NASA Astrophysics Data System (ADS)

Kuo, Eric; Wieman, Carl E.

2015-12-01

Broad instructional methods like "interactive engagement" have been shown to be effective, but such general characterization provides little guidance on the details of how to structure instructional materials. In this study, we seek instructional specificity by comparing two ways of using an analogy to learn a target physical principle: (i) applying the analogy to the target physical domain on a case-by-case basis and (ii) using the analogy to create a general rule in the target physical domain. In the discussion sections of a large, introductory physics course (N =2 3 1 ), students who sought a general rule were better able to discover and apply a correct physics principle than students who analyzed the examples case by case. The difference persisted at a reduced level after subsequent direct instruction. We argue that students who performed case-by-case analyses were more likely to focus on idiosyncratic problem-specific features rather than the deep structural features. This study provides an example of investigations into how the specific structure of instructional materials can be consequential for what is learned.

Three-dimensional massive gravity and the bigravity black hole

NASA Astrophysics Data System (ADS)

Bañados, Máximo; Theisen, Stefan

2009-11-01

We study three-dimensional massive gravity formulated as a theory with two dynamical metrics, like the f-g theories of Isham-Salam and Strathdee. The action is parity preserving and has no higher derivative terms. The spectrum contains a single massive graviton. This theory has several features discussed recently in TMG and NMG. We find warped black holes, a critical point, and generalized Brown-Henneaux boundary conditions.

Configurational coupled cluster approach with applications to magnetic model systems

NASA Astrophysics Data System (ADS)

Wu, Siyuan; Nooijen, Marcel

2018-05-01

A general exponential, coupled cluster like, approach is discussed to extract an effective Hamiltonian in configurational space, as a sum of 1-body, 2-body up to n-body operators. The simplest two-body approach is illustrated by calculations on simple magnetic model systems. A key feature of the approach is that equations up to a certain rank do not depend on higher body cluster operators.

HIV and the decriminalization of sex work in New Zealand.

PubMed

Healy, Catherine

2006-12-01

The decriminalization of sex work in New Zealand will protect the rights of sex workers and improve their working conditions and general well-being. It will also improve HIV prevention programs. In this article, which is based on a presentation at a "learning from practice" session at the conference, Catherine Healy describes the situation prior to decriminalization, and discusses the features of the new law and accompanying guidelines.

Determinism, risk and safe driving behavior in northern Alberta, Canada.

PubMed

Rothe, J Peter; Elgert, Laureen

2003-09-01

There is evidence that Alberta's rural north is over-represented in the Canadian province's overall traffic fatality rate, even after weather, travel exposure and highway geometry are controlled for. The objective of this study was to identify underlying reasons and rationales that northern citizens use to accommodate risk and driving behavior. A total of 82 individuals participated in 13 focus groups, each with between 5 and 10 participants. Eight focus groups were conducted with general drivers and five with service professionals in five different Alberta locations. Discussions centered on a series of questions that were designed to elicit insight into general characteristics of the participants' world-view and featured two categories of questions, including dimensions of belief systems and driver characteristics and behavior. Although much of the discussions focused on freedom of choice, over half of the interviewees cited determinism as a key feature of responsibility. Three versions of determinism were emphasized as key in roadway safety: religious determinism, 'universal' determinism (fatalism), and humanistic determinism. These observations highlighted peoples' perception of the likelihood of getting into traffic situations outside one's control. In order to maximize the effectiveness of traffic safety in the north, professionals need to take an approach which addresses not only safety issues, but also issues regarding responsibility and its links with behavior.

The rules of information aggregation and emergence of collective intelligent behavior.

PubMed

Bettencourt, Luís M A

2009-10-01

Information is a peculiar quantity. Unlike matter and energy, which are conserved by the laws of physics, the aggregation of knowledge from many sources can in fact produce more information (synergy) or less (redundancy) than the sum of its parts. This feature can endow groups with problem-solving strategies that are superior to those possible among noninteracting individuals and, in turn, may provide a selection drive toward collective cooperation and coordination. Here we explore the formal properties of information aggregation as a general principle for explaining features of social organization. We quantify information in terms of the general formalism of information theory, which also prescribes the rules of how different pieces of evidence inform the solution of a given problem. We then show how several canonical examples of collective cognition and coordination can be understood through principles of minimization of uncertainty (maximization of predictability) under information pooling over many individuals. We discuss in some detail how collective coordination in swarms, markets, natural language processing, and collaborative filtering may be guided by the optimal aggregation of information in social collectives. We also identify circumstances when these processes fail, leading, for example, to inefficient markets. The contrast to approaches to understand coordination and collaboration via decision and game theory is also briefly discussed. Copyright © 2009 Cognitive Science Society, Inc.

Statistical Methods for Proteomic Biomarker Discovery based on Feature Extraction or Functional Modeling Approaches.

PubMed

Morris, Jeffrey S

2012-01-01

In recent years, developments in molecular biotechnology have led to the increased promise of detecting and validating biomarkers, or molecular markers that relate to various biological or medical outcomes. Proteomics, the direct study of proteins in biological samples, plays an important role in the biomarker discovery process. These technologies produce complex, high dimensional functional and image data that present many analytical challenges that must be addressed properly for effective comparative proteomics studies that can yield potential biomarkers. Specific challenges include experimental design, preprocessing, feature extraction, and statistical analysis accounting for the inherent multiple testing issues. This paper reviews various computational aspects of comparative proteomic studies, and summarizes contributions I along with numerous collaborators have made. First, there is an overview of comparative proteomics technologies, followed by a discussion of important experimental design and preprocessing issues that must be considered before statistical analysis can be done. Next, the two key approaches to analyzing proteomics data, feature extraction and functional modeling, are described. Feature extraction involves detection and quantification of discrete features like peaks or spots that theoretically correspond to different proteins in the sample. After an overview of the feature extraction approach, specific methods for mass spectrometry ( Cromwell ) and 2D gel electrophoresis ( Pinnacle ) are described. The functional modeling approach involves modeling the proteomic data in their entirety as functions or images. A general discussion of the approach is followed by the presentation of a specific method that can be applied, wavelet-based functional mixed models, and its extensions. All methods are illustrated by application to two example proteomic data sets, one from mass spectrometry and one from 2D gel electrophoresis. While the specific methods presented are applied to two specific proteomic technologies, MALDI-TOF and 2D gel electrophoresis, these methods and the other principles discussed in the paper apply much more broadly to other expression proteomics technologies.

Description of data on the Nimbus 7 LIMS map archive tape: Temperature and geopotential height

NASA Technical Reports Server (NTRS)

Haggard, K. V.; Remsberg, E. E.; Grose, W. L.; Russell, J. M., III; Marshall, B. T.; Lingenfelser, G.

1986-01-01

The process by which the analysis of the Limb Infared Monitor of the Stratosphere (LIMS) experiment data were used to produce estimates of synoptic maps of temperature and geopotential height is described. In addition to a detailed description of the analysis procedure, several interesting features in the data are discussed and these features are used to demonstrate how the analysis procedure produced the final maps and how one can estimate the uncertainties in the maps. In addition, features in the analysis are noted that would influence how one might use, or interpret, the results. These include subjects such as smoothing and the interpretation of wave components. While some suggestions are made for an improved analysis of the data, it is shown that, in general, the maps are an excellent estimation of the synoptic fields.

Research progress on Drosophila visual cognition in China.

PubMed

Guo, AiKe; Zhang, Ke; Peng, YueQin; Xi, Wang

2010-03-01

Visual cognition, as one of the fundamental aspects of cognitive neuroscience, is generally associated with high-order brain functions in animals and human. Drosophila, as a model organism, shares certain features of visual cognition in common with mammals at the genetic, molecular, cellular, and even higher behavioral levels. From learning and memory to decision making, Drosophila covers a broad spectrum of higher cognitive behaviors beyond what we had expected. Armed with powerful tools of genetic manipulation in Drosophila, an increasing number of studies have been conducted in order to elucidate the neural circuit mechanisms underlying these cognitive behaviors from a genes-brain-behavior perspective. The goal of this review is to integrate the most important studies on visual cognition in Drosophila carried out in mainland China during the last decade into a body of knowledge encompassing both the basic neural operations and circuitry of higher brain function in Drosophila. Here, we consider a series of the higher cognitive behaviors beyond learning and memory, such as visual pattern recognition, feature and context generalization, different feature memory traces, salience-based decision, attention-like behavior, and cross-modal leaning and memory. We discuss the possible general gain-gating mechanism implementing by dopamine - mushroom body circuit in fly's visual cognition. We hope that our brief review on this aspect will inspire further study on visual cognition in flies, or even beyond.

Layered Deposits and Pitted Terrain in the Circum Hellas Region

NASA Technical Reports Server (NTRS)

Moore, J. M.; Howard, A. D.

2005-01-01

Much of the southern highlands has been mantled since the Noachian, including a general blanket of possibly airfall-derived sediment that softens the landscape, the Electris mantle including knobby chaos in several basins, and a variety of deposits that are the subject of this study that share the common characteristics of being generally confined to basins and crater floors and that manifest irregular interior depressions. Many of these features occur in a zone surrounding Hellas. These deposits share the general characteristics of having fairly smooth, nearly planar surfaces and abrupt scarps bordering interior and marginal depressions. Despite these common characteristics, a wide range of morphologies occurs. Several end-members are discussed below. Additional information is included in the original extended abstract.

Use of liquefaction-induced features for paleoseismic analysis - An overview of how seismic liquefaction features can be distinguished from other features and how their regional distribution and properties of source sediment can be used to infer the location and strength of Holocene paleo-earthquakes

USGS Publications Warehouse

Obermeier, S.F.

1996-01-01

Liquefaction features can be used in many field settings to estimate the recurrence interval and magnitude of strong earthquakes through much of the Holocene. These features include dikes, craters, vented sand, sills, and laterally spreading landslides. The relatively high seismic shaking level required for their formation makes them particularly valuable as records of strong paleo-earthquakes. This state-of-the-art summary for using liquefaction-induced features for paleoseismic interpretation and analysis takes into account both geological and geotechnical engineering perspectives. The driving mechanism for formation of the features is primarily the increased pore-water pressure associated with liquefaction of sand-rich sediment. The role of this mechanism is often supplemented greatly by the direct action of seismic shaking at the ground surface, which strains and breaks the clay-rich cap that lies immediately above the sediment that liquefied. Discussed in the text are the processes involved in formation of the features, as well as their morphology and characteristics in field settings. Whether liquefaction occurs is controlled mainly by sediment grain size, sediment packing, depth to the water table, and strength and duration of seismic shaking. Formation of recognizable features in the field generally requires a low-permeability cap above the sediment that liquefied. Field manifestations are controlled largely by the severity of liquefaction and the thickness and properties of the low-permeability cap. Criteria are presented for determining whether observed sediment deformation in the field originated by seismically induced liquefaction. These criteria have been developed mainly by observing historic effects of liquefaction in varied field settings. The most important criterion is that a seismic liquefaction origin requires widespread, regional development of features around a core area where the effects are most severe. In addition, the features must have a morphology that is consistent with a very sudden application of a large hydraulic force. This article discusses case studies in widely separated and different geological settings: coastal South Carolina, the New Madrid seismic zone, the Wabash Valley seismic zone, and coastal Washington State. These studies encompass most of the range of settings and the types of liquefaction-induced features likely to be encountered anywhere. The case studies describe the observed features and the logic for assigning a seismic liquefaction origin to them. Also discussed are some types of sediment deformations that can be misinterpreted as having a seismic origin. Two independent methods for estimating prehistoric magnitude are discussed briefly. One method is based on determination of the maximum distance from the epicenter over which liquefaction-induced effects have formed. The other method is based on use of geotechnical engineering techniques at sites of marginal liquefaction, in order to bracket the peak accelerations as a function of epicentral distance; these accelerations can then be compared with predictions from seismological models.

Star Formation Studies with SOFIA and its Synergy with TMT

NASA Astrophysics Data System (ADS)

De Buizer, James

2014-07-01

The Stratospheric Observatory For Infrared Astronomy (SOFIA) is a modified Boeing 747 aircraft equipped with a 2.5m telescope that performs observations at high altitude from the optical to the sub-mm. The observatory just reached full operational capability in April of this year. Given that it is slated for a 20-year mission lifetime, SOFIA will overlap TMT by more than a decade. I will discuss the contrasting and complementary features of SOFIA and TMT in the context of star formation, discuss some of the early results from SOFIA in this field, and finish with a discussion of how TMT data can enhance and extended our understanding of star formation processes.[This talk could also be generalized to discuss more about synergies between SOFIA and TMT in a broader context (not just star formation), should the organizers prefer that.

Anesthetic management of Costello syndrome: a case report.

PubMed

Williams, Christol

2014-04-01

Costello syndrome is a rare genetic disorder with an estimated 300 medical cases worldwide. Typical features that characterize this syndrome include short stature, macrocephaly, developmental delay, loose skin folds, distinctive coarse facial features, and multiorgan system anomalies. The following case report discusses the anesthetic management for a 3-year-old boy undergoing general anesthesia for a scheduled dental restoration, hydrocelectomy, inguinal hernia repair, and bilateral myringotomy with placement of pressure equalization tubes. A scarcity of literature for the anesthetic management of Costello syndrome (also known as faciocutaneoskeletal syndrome) exists. Utilizing an overview of the pertinent literature, clinical practice recommendations are suggested for the anesthetic implications of managing a pediatric patient with this rare syndrome.

Modeling of electrical and mesoscopic circuits at quantum nanoscale from heat momentum operator

NASA Astrophysics Data System (ADS)

El-Nabulsi, Rami Ahmad

2018-04-01

We develop a new method to study electrical circuits at quantum nanoscale by introducing a heat momentum operator which reproduces quantum effects similar to those obtained in Suykens's nonlocal-in-time kinetic energy approach for the case of reversible motion. The series expansion of the heat momentum operator is similar to the momentum operator obtained in the framework of minimal length phenomenologies characterized by the deformation of Heisenberg algebra. The quantization of both LC and mesoscopic circuits revealed a number of motivating features like the emergence of a generalized uncertainty relation and a minimal charge similar to those obtained in the framework of minimal length theories. Additional features were obtained and discussed accordingly.

Mechanical monolithic compact sensors for real-time linear and angular broadband low frequency monitoring and control of spacecrafts and satellites

NASA Astrophysics Data System (ADS)

Barone, F.; Giordano, G.

2017-09-01

In this paper we describe the characteristics and performances of a monolithic sensor designed for low frequency motion measurement of spacecrafts and satellites, whose mechanics is based on the UNISA Folded Pendulum. The latter, developed for ground-based applications, exhibits unique features (compactness, lightness, scalability, low resonance frequency and high quality factor), consequence of the action of the gravitational force on its inertial mass. In this paper we introduce and discuss the general methodology used to extend the application of ground-based folded pendulums to space, also in total absence of gravity, still keeping all their peculiar features and characteristics.

The Thermodynamics of General and Local Anesthesia

PubMed Central

Græsbøll, Kaare; Sasse-Middelhoff, Henrike; Heimburg, Thomas

2014-01-01

General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase. Such a generic law provides physical justification of the famous Meyer-Overton rule. We show here that general anesthetics, barbiturates, and local anesthetics all display the same effect on melting transitions. Their effect is reversed by hydrostatic pressure. Thus, the thermodynamic behavior of local anesthetics is very similar to that of general anesthetics. We present a detailed thermodynamic analysis of heat capacity profiles of membranes in the presence of anesthetics. Using this analysis, we are able to describe experimentally observed calorimetric profiles and predict the anesthetic features of arbitrary molecules. In addition, we discuss the thermodynamic origin of the cutoff effect of long-chain alcohols and the additivity of the effect of general and local anesthetics. PMID:24853743

The Thermodynamics of General and Local Anesthesia

NASA Astrophysics Data System (ADS)

Græsbøll, Kaare; Sasse-Middelhoff, Henrike; Heimburg, Thomas

2014-05-01

General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase. Such a generic law provides physical justification of the famous Meyer-Overton rule. We show here that general anesthetics, barbiturates and local anesthetics all display the same effect on melting transitions. Their effect is reversed by hydrostatic pressure. Thus, the thermodynamic behavior of local anesthetics is very similar to that of general anesthetics. We present a detailed thermodynamic analysis of heat capacity profiles of membranes in the presence of anesthetics. This analysis is able to describe experimentally observed calorimetric profiles and permits prediction of the anesthetic features of arbitrary molecules. In addition, we discuss the thermodynamic origin of the cutoff-effect of long-chain alcohols and the additivity of the effect of general and local anesthetics.

Unconscious knowledge: A survey

PubMed Central

Augusto, Luís M.

2011-01-01

The concept of unconscious knowledge is fundamental for an understanding of human thought processes and mentation in general; however, the psychological community at large is not familiar with it. This paper offers a survey of the main psychological research currently being carried out into cognitive processes, and examines pathways that can be integrated into a discipline of unconscious knowledge. It shows that the field has already a defined history and discusses some of the features that all kinds of unconscious knowledge seem to share at a deeper level. With the aim of promoting further research, we discuss the main challenges which the postulation of unconscious cognition faces within the psychological community. PMID:21814538

AgRISTARS. Supporting research: Algorithms for scene modelling

NASA Technical Reports Server (NTRS)

Rassbach, M. E. (Principal Investigator)

1982-01-01

The requirements for a comprehensive analysis of LANDSAT or other visual data scenes are defined. The development of a general model of a scene and a computer algorithm for finding the particular model for a given scene is discussed. The modelling system includes a boundary analysis subsystem, which detects all the boundaries and lines in the image and builds a boundary graph; a continuous variation analysis subsystem, which finds gradual variations not well approximated by a boundary structure; and a miscellaneous features analysis, which includes texture, line parallelism, etc. The noise reduction capabilities of this method and its use in image rectification and registration are discussed.

Hybrid plasmonic systems: from optical transparencies to strong coupling and entanglement

NASA Astrophysics Data System (ADS)

Gray, Stephen K.

2018-02-01

Classical electrodynamics and quantum mechanical models of quantum dots and molecules interacting with plasmonic systems are discussed. Calculations show that just one quantum dot interacting with a plasmonic system can lead to interesting optical effects, including optical transparencies and more general Fano resonance features that can be tailored with ultrafast laser pulses. Such effects can occur in the limit of moderate coupling between quantum dot and plasmonic system. The approach to the strong coupling regime is also discussed. In cases with two or more quantum dots within a plasmonic system, the possibility of quantum entanglement mediated through the dissipative plasmonic structure arises.

Artistic forms and complexity.

PubMed

Boon, J-P; Casti, J; Taylor, R P

2011-04-01

We discuss the inter-relationship between various concepts of complexity by introducing a complexity 'triangle' featuring objective complexity, subjective complexity and social complexity. Their connections are explored using visual and musical compositions of art. As examples, we quantify the complexity embedded within the paintings of the Jackson Pollock and the musical works of Johann Sebastian Bach. We discuss the challenges inherent in comparisons of the spatial patterns created by Pollock and the sonic patterns created by Bach, including the differing roles that time plays in these investigations. Our results draw attention to some common intriguing characteristics suggesting 'universality' and conjecturing that the fractal nature of art might have an intrinsic value of more general significance.

The landing flare: An analysis and flight-test investigation

NASA Technical Reports Server (NTRS)

Seckel, E.

1975-01-01

Results are given of an extensive investigation of conventional landing flares in general aviation type airplanes. A wide range of parameters influencing flare behavior are simulated in experimental landings in a variable-stability Navion. The most important feature of the flare is found to be the airplane's deceleration in the flare. Various effects on this are correlated in terms of the average flare load factor. Piloting technique is extensively discussed. Design criteria are presented.

[Frontal fibrosing alopecia: case series and literature review].

PubMed

Tinoco-Fragoso, Fátima; Domínguez-Cherit, Judith; Méndez-Flores, Silvia

2017-01-01

Frontal fibrosing alopecia is a disease characterized by a symmetric and progressive loss of hair in the fronto-temporal and fronto-parietal lines that generally affects postmenopausal women. It is considered a variant of lichen planus pilaris for its clinical and histopathological features; although, its etiopathology is still unknown. In this report, we analyzed 4 cases of this disease and we discussed its clinical and histopathological characteristics, as well as their course after initiating treatment.

Methods and strategies of object localization

NASA Technical Reports Server (NTRS)

Shao, Lejun; Volz, Richard A.

1989-01-01

An important property of an intelligent robot is to be able to determine the location of an object in 3-D space. A general object localization system structure is proposed, some important issues on localization discussed, and an overview given for current available object localization algorithms and systems. The algorithms reviewed are characterized by their feature extracting and matching strategies; the range finding methods; the types of locatable objects; and the mathematical formulating methods.

Significant Wilderness Qualities: Can They Be Identified and Monitored? Proceedings of the Annual NOLS [National Outdoor Leadership School] Wilderness Research Colloquium (3rd, Shoshone National Forest, Wyoming, August 10-15, 1987).

ERIC Educational Resources Information Center

Cole, David N., Comp.; Lucas, Robert C., Comp.

This report is a compilation of the papers presented at a colloquium on wilderness management and a synopsis of discussions held during the conference. The conference theme was how to determine and monitor the most significant features and qualities of the wilderness resource. Generally, participants identify solitude; pollution-free air and…

Unraveling hadron structure with generalized parton distributions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andrei Belitsky; Anatoly Radyushkin

2004-10-01

The recently introduced generalized parton distributions have emerged as a universal tool to describe hadrons in terms of quark and gluonic degrees of freedom. They combine the features of form factors, parton densities and distribution amplitudes - the functions used for a long time in studies of hadronic structure. Generalized parton distributions are analogous to the phase-space Wigner quasi-probability function of non-relativistic quantum mechanics which encodes full information on a quantum-mechanical system. We give an extensive review of main achievements in the development of this formalism. We discuss physical interpretation and basic properties of generalized parton distributions, their modeling andmore » QCD evolution in the leading and next-to-leading orders. We describe how these functions enter a wide class of exclusive reactions, such as electro- and photo-production of photons, lepton pairs, or mesons.« less

What is "Object-Oriented Programming"?

NASA Astrophysics Data System (ADS)

Stroustrup, Bjarne

"Object-Oriented Programming" and "Data Abstraction" have become very common terms. Unfortunately, few people agree on what they mean. I will offer informal definitions that appear to make sense in the context of languages like Ada, C++, Modula-2, Simula67, and Smalltalk. The general idea is to equate "support for data abstraction" with the ability to define and use new types and equate "support for object-oriented programming" with the ability to express type hierarchies. Features necessary to support these programming styles in a general purpose programming language will be discussed. The presentation centers around C++ but is not limited to facilities provided by that language.

Multilevel water governance and problems of scale: setting the stage for a broader debate.

PubMed

Moss, Timothy; Newig, Jens

2010-07-01

Environmental governance and management are facing a multiplicity of challenges related to spatial scales and multiple levels of governance. Water management is a field particularly sensitive to issues of scale because the hydrological system with its different scalar levels from small catchments to large river basins plays such a prominent role. It thus exemplifies fundamental issues and dilemmas of scale in modern environmental management and governance. In this introductory article to an Environmental Management special feature on "Multilevel Water Governance: Coping with Problems of Scale," we delineate our understanding of problems of scale and the dimensions of scalar politics that are central to water resource management. We provide an overview of the contributions to this special feature, concluding with a discussion of how scalar research can usefully challenge conventional wisdom on water resource management. We hope that this discussion of water governance stimulates a broader debate and inquiry relating to the scalar dimensions of environmental governance and management in general.

Artificial neural networks in mammography interpretation and diagnostic decision making.

PubMed

Ayer, Turgay; Chen, Qiushi; Burnside, Elizabeth S

2013-01-01

Screening mammography is the most effective means for early detection of breast cancer. Although general rules for discriminating malignant and benign lesions exist, radiologists are unable to perfectly detect and classify all lesions as malignant and benign, for many reasons which include, but are not limited to, overlap of features that distinguish malignancy, difficulty in estimating disease risk, and variability in recommended management. When predictive variables are numerous and interact, ad hoc decision making strategies based on experience and memory may lead to systematic errors and variability in practice. The integration of computer models to help radiologists increase the accuracy of mammography examinations in diagnostic decision making has gained increasing attention in the last two decades. In this study, we provide an overview of one of the most commonly used models, artificial neural networks (ANNs), in mammography interpretation and diagnostic decision making and discuss important features in mammography interpretation. We conclude by discussing several common limitations of existing research on ANN-based detection and diagnostic models and provide possible future research directions.

Discrimination of artificial categories structured by family resemblances: a comparative study in people (Homo sapiens) and pigeons (Columba livia).

PubMed

Makino, Hiroshi; Jitsumori, Masako

2007-02-01

Adult humans (Homo sapiens) and pigeons (Columba livia) were trained to discriminate artificial categories that the authors created by mimicking 2 properties of natural categories. One was a family resemblance relationship: The highly variable exemplars, including those that did not have features in common, were structured by a similarity network with the features correlating to one another in each category. The other was a polymorphous rule: No single feature was essential for distinguishing the categories, and all the features overlapped between the categories. Pigeons learned the categories with ease and then showed a prototype effect in accord with the degrees of family resemblance for novel stimuli. Some evidence was also observed for interactive effects of learning of individual exemplars and feature frequencies. Humans had difficulty in learning the categories. The participants who learned the categories generally responded to novel stimuli in an all-or-none fashion on the basis of their acquired classification decision rules. The processes that underlie the classification performances of the 2 species are discussed.

A feature selection approach towards progressive vector transmission over the Internet

NASA Astrophysics Data System (ADS)

Miao, Ru; Song, Jia; Feng, Min

2017-09-01

WebGIS has been applied for visualizing and sharing geospatial information popularly over the Internet. In order to improve the efficiency of the client applications, the web-based progressive vector transmission approach is proposed. Important features should be selected and transferred firstly, and the methods for measuring the importance of features should be further considered in the progressive transmission. However, studies on progressive transmission for large-volume vector data have mostly focused on map generalization in the field of cartography, but rarely discussed on the selection of geographic features quantitatively. This paper applies information theory for measuring the feature importance of vector maps. A measurement model for the amount of information of vector features is defined based upon the amount of information for dealing with feature selection issues. The measurement model involves geometry factor, spatial distribution factor and thematic attribute factor. Moreover, a real-time transport protocol (RTP)-based progressive transmission method is then presented to improve the transmission of vector data. To clearly demonstrate the essential methodology and key techniques, a prototype for web-based progressive vector transmission is presented, and an experiment of progressive selection and transmission for vector features is conducted. The experimental results indicate that our approach clearly improves the performance and end-user experience of delivering and manipulating large vector data over the Internet.

A hybrid perturbation-Galerkin method for differential equations containing a parameter

NASA Technical Reports Server (NTRS)

Geer, James F.; Andersen, Carl M.

1989-01-01

A two-step hybrid perturbation-Galerkin method to solve a variety of differential equations which involve a parameter is presented and discussed. The method consists of: (1) the use of a perturbation method to determine the asymptotic expansion of the solution about one or more values of the parameter; and (2) the use of some of the perturbation coefficient functions as trial functions in the classical Bubnov-Galerkin method. This hybrid method has the potential of overcoming some of the drawbacks of the perturbation method and the Bubnov-Galerkin method when they are applied by themselves, while combining some of the good features of both. The proposed method is illustrated first with a simple linear two-point boundary value problem and is then applied to a nonlinear two-point boundary value problem in lubrication theory. The results obtained from the hybrid method are compared with approximate solutions obtained by purely numerical methods. Some general features of the method, as well as some special tips for its implementation, are discussed. A survey of some current research application areas is presented and its degree of applicability to broader problem areas is discussed.

Crack propagation and arrest in CFRP materials with strain softening regions

NASA Astrophysics Data System (ADS)

Dilligan, Matthew Anthony

Understanding the growth and arrest of cracks in composite materials is critical for their effective utilization in fatigue-sensitive and damage susceptible applications such as primary aircraft structures. Local tailoring of the laminate stack to provide crack arrest capacity intermediate to major structural components has been investigated and demonstrated since some of the earliest efforts in composite aerostructural design, but to date no rigorous model of the crack arrest mechanism has been developed to allow effective sizing of these features. To address this shortcoming, the previous work in the field is reviewed, with particular attention to the analysis methodologies proposed for similar arrest features. The damage and arrest processes active in such features are investigated, and various models of these processes are discussed and evaluated. Governing equations are derived based on a proposed mechanistic model of the crack arrest process. The derived governing equations are implemented in a numerical model, and a series of simulations are performed to ascertain the general characteristics of the proposed model and allow qualitative comparison to existing experimental results. The sensitivity of the model and the arrest process to various parameters is investigated, and preliminary conclusions regarding the optimal feature configuration are developed. To address deficiencies in the available material and experimental data, a series of coupon tests are developed and conducted covering a range of arrest zone configurations. Test results are discussed and analyzed, with a particular focus on identification of the proposed failure and arrest mechanisms. Utilizing the experimentally derived material properties, the tests are reproduced with both the developed numerical tool as well as a FEA-based implementation of the arrest model. Correlation between the simulated and experimental results is analyzed, and future avenues of investigation are identified. Utilizing the developed model, a sensitivity study is conducted to assess the current proposed arrest configuration. Optimum distribution and sizing of the arrest zones is investigated, and general design guidelines are developed.

An ensemble method for extracting adverse drug events from social media.

PubMed

Liu, Jing; Zhao, Songzheng; Zhang, Xiaodi

2016-06-01

Because adverse drug events (ADEs) are a serious health problem and a leading cause of death, it is of vital importance to identify them correctly and in a timely manner. With the development of Web 2.0, social media has become a large data source for information on ADEs. The objective of this study is to develop a relation extraction system that uses natural language processing techniques to effectively distinguish between ADEs and non-ADEs in informal text on social media. We develop a feature-based approach that utilizes various lexical, syntactic, and semantic features. Information-gain-based feature selection is performed to address high-dimensional features. Then, we evaluate the effectiveness of four well-known kernel-based approaches (i.e., subset tree kernel, tree kernel, shortest dependency path kernel, and all-paths graph kernel) and several ensembles that are generated by adopting different combination methods (i.e., majority voting, weighted averaging, and stacked generalization). All of the approaches are tested using three data sets: two health-related discussion forums and one general social networking site (i.e., Twitter). When investigating the contribution of each feature subset, the feature-based approach attains the best area under the receiver operating characteristics curve (AUC) values, which are 78.6%, 72.2%, and 79.2% on the three data sets. When individual methods are used, we attain the best AUC values of 82.1%, 73.2%, and 77.0% using the subset tree kernel, shortest dependency path kernel, and feature-based approach on the three data sets, respectively. When using classifier ensembles, we achieve the best AUC values of 84.5%, 77.3%, and 84.5% on the three data sets, outperforming the baselines. Our experimental results indicate that ADE extraction from social media can benefit from feature selection. With respect to the effectiveness of different feature subsets, lexical features and semantic features can enhance the ADE extraction capability. Kernel-based approaches, which can stay away from the feature sparsity issue, are qualified to address the ADE extraction problem. Combining different individual classifiers using suitable combination methods can further enhance the ADE extraction effectiveness. Copyright © 2016 Elsevier B.V. All rights reserved.

A predictive transport modeling code for ICRF-heated tokamaks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillips, C.K.; Hwang, D.Q.; Houlberg, W.

In this report, a detailed description of the physic included in the WHIST/RAZE package as well as a few illustrative examples of the capabilities of the package will be presented. An in depth analysis of ICRF heating experiments using WHIST/RAZE will be discussed in a forthcoming report. A general overview of philosophy behind the structure of the WHIST/RAZE package, a summary of the features of the WHIST code, and a description of the interface to the RAZE subroutines are presented in section 2 of this report. Details of the physics contained in the RAZE code are examined in section 3.more » Sample results from the package follow in section 4, with concluding remarks and a discussion of possible improvements to the package discussed in section 5.« less

A predictive transport modeling code for ICRF-heated tokamaks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillips, C.K.; Hwang, D.Q.; Houlberg, W.

1992-02-01

In this report, a detailed description of the physic included in the WHIST/RAZE package as well as a few illustrative examples of the capabilities of the package will be presented. An in depth analysis of ICRF heating experiments using WHIST/RAZE will be discussed in a forthcoming report. A general overview of philosophy behind the structure of the WHIST/RAZE package, a summary of the features of the WHIST code, and a description of the interface to the RAZE subroutines are presented in section 2 of this report. Details of the physics contained in the RAZE code are examined in section 3.more » Sample results from the package follow in section 4, with concluding remarks and a discussion of possible improvements to the package discussed in section 5.« less

Cloud, Aerosol, and Volcanic Ash Retrievals Using ASTR and SLSTR with ORAC

NASA Astrophysics Data System (ADS)

McGarragh, Gregory; Poulsen, Caroline; Povey, Adam; Thomas, Gareth; Christensen, Matt; Sus, Oliver; Schlundt, Cornelia; Stapelberg, Stefan; Stengel, Martin; Grainger, Don

2015-12-01

The Optimal Retrieval of Aerosol and Cloud (ORAC) is a generalized optimal estimation system that retrieves cloud, aerosol and volcanic ash parameters using satellite imager measurements in the visible to infrared. Use of the same algorithm for different sensors and parameters leads to consistency that facilitates inter-comparison and interaction studies. ORAC currently supports ATSR, AVHRR, MODIS and SEVIRI. In this proceeding we discuss the ORAC retrieval algorithm applied to ATSR data including the retrieval methodology, the forward model, uncertainty characterization and discrimination/classification techniques. Application of ORAC to SLSTR data is discussed including the additional features that SLSTR provides relative to the ATSR heritage. The ORAC level 2 and level 3 results are discussed and an application of level 3 results to the study of cloud/aerosol interactions is presented.

Building Facade Reconstruction by Fusing Terrestrial Laser Points and Images

PubMed Central

Pu, Shi; Vosselman, George

2009-01-01

Laser data and optical data have a complementary nature for three dimensional feature extraction. Efficient integration of the two data sources will lead to a more reliable and automated extraction of three dimensional features. This paper presents a semiautomatic building facade reconstruction approach, which efficiently combines information from terrestrial laser point clouds and close range images. A building facade's general structure is discovered and established using the planar features from laser data. Then strong lines in images are extracted using Canny extractor and Hough transformation, and compared with current model edges for necessary improvement. Finally, textures with optimal visibility are selected and applied according to accurate image orientations. Solutions to several challenge problems throughout the collaborated reconstruction, such as referencing between laser points and multiple images and automated texturing, are described. The limitations and remaining works of this approach are also discussed. PMID:22408539

Morphologic interpretation of fertile structures in glossopterid gymnosperms

USGS Publications Warehouse

Schopf, J.M.

1976-01-01

The problem of determining affinity among glossopterid gymnosperms is beset by deficiencies in preservation, natural dissociation of parts, and scarcity of features assuredly critical for morphologic comprarison. The glossopterids probably are not a very heterogeneous group of plants, but this is difficult to prove. The Gondwana glacial "hiatus" has resulted in the omission of a critical chapter glossopterid evolution. As a consequence, morphologic features and phyletic probabilities must be evaluated on a much more hypothetical basis than would otherwise be justified. Confusion has arisen from the lack of morphologic terms that permit clear discussion of a newly evolved type of reproductive structure in glossopterids. The structure, here designated a "fertiliger", consists of a leafy bract, a partially adnate stalk, and a fertile head or capitulum. Seven types of fertile structures are discussed, all of which are bilaterally symmetrical and have different features on dorsiventral surfaces. I regard all fertiligers as ovulate but this interpretation may bot be acceptable to some workers; others may not accept dorsiventral organization of the capitulum as being fundamental. Among glossopterids, however, in spite of differences in preservation that may seem to support a variant interpretation, these ovulate fertiligers are the distinctive features that show general consistency. A single fertile bract bearing several capitula, as exemplified by Lidgettonia, is called a compound fertiliger. Staminate structures (microsporophylls) of glossopterids are separately classified as Eretmonia, Glossotheca, and possibly as other taxa. Only the manner of sporangial attachment is not entirely clear. It seems likely the staminate parts have previously been confused with scale leaves and are actually coextensive in distribution with the glossopterids. A tentative phyletic model suggests the distant derivation of glossopterids from middle Carboniferous cordaiteans. Many details must be speculative due to the lack of a pertinent fossil record, but this interpretation accounts for some features that have no counterpart in pteridosperms. Permineralized ovules from Antarctica provide general support for this working hypothesis, but specific evidence is lacking. Furthermore, it seems unlikely angiosperms originated from glossopterids; it is more reasonable to consider the glossopterids as possible distant ancestors of the Gnetales. ?? 1976.

Care home design for people with dementia: What do people with dementia and their family carers value?

PubMed

Innes, Anthea; Kelly, Fiona; Dincarslan, Ozlem

2011-07-01

To report on the views of people with dementia who live in care homes and their family carers on aspects of design that are important to them, and discuss these in relation to developing physical care environments that respond to the wishes of people with dementia and their family carers. Six focus groups were held: two in Northern Ireland and four in Scotland. A total of 40 people participated in the focus groups. Twenty nine people were with dementia (24 female and five male), and 11 were family carers (10 female and one male). Carers discussed the features of a building they took into account when selecting a care home, and discussed this in relation to 'bricks and mortar versus people'. Key themes reported by people with dementia and their family carers included how the space in the environment is used, for example, what happens in the building and the presence or absence of certain design features. Outside space and wayfinding aids were identified as positive features of the home, along with a general lack of concern about ensuite provision. The results demonstrate the complexity of building design as it must provide living space acceptable to people with dementia living there and family members who visit, as well as provide a workable environment for staff. The findings highlight areas that should be considered by care home teams involved in the build of a new home or the redevelopment of an existing care home.

A review of techniques to determine alternative selection in design for remanufacturing

NASA Astrophysics Data System (ADS)

Noor, A. Z. Mohamed; Fauadi, M. H. F. Md; Jafar, F. A.; Mohamad, N. R.; Yunos, A. S. Mohd

2017-10-01

This paper discusses the techniques used for optimization in manufacturing system. Although problem domain is focused on sustainable manufacturing, techniques used to optimize general manufacturing system were also discussed. Important aspects of Design for Remanufacturing (DFReM) considered include indexes, weighted average, grey decision making and Fuzzy TOPSIS. The limitation of existing techniques are most of them is highly based on decision maker’s perspective. Different experts may have different understanding and eventually scale it differently. Therefore, the objective of this paper is to determine available techniques and identify the lacking feature in it. Once all the techniques have been reviewed, a decision will be made by create another technique which should counter the lacking of discussed techniques. In this paper, shows that the hybrid computation of Fuzzy Analytic Hierarchy Process (AHP) and Artificial Neural Network (ANN) is suitable and fill the gap of all discussed technique.

Qudit hypergraph states and their properties

NASA Astrophysics Data System (ADS)

Xiong, Fei-Lei; Zhen, Yi-Zheng; Cao, Wen-Fei; Chen, Kai; Chen, Zeng-Bing

2018-01-01

Hypergraph states, a generalization of graph states, constitute a large class of quantum states with intriguing nonlocal properties, and they have promising applications in quantum information science and technology. In this paper, we study some features of an independently proposed generalization of hypergraph states to qudit hypergraph states, i.e., each vertex in the generalized hypergraph (multi-hypergraph) represents a d -level system instead of a two-level one. It is shown that multi-hypergraphs and d -level hypergraph states have a one-to-one correspondence, and the structure of a multi-hypergraph exhibits the entanglement property of the corresponding quantum state. We discuss their relationship with some well-known state classes, e.g., real equally weighted states and stabilizer states. The Bell nonlocality, an important resource in fulfilling many quantum information tasks, is also investigated.

Apollo program flight summary report: Apollo missions AS-201 through Apollo 16, revision 11

NASA Technical Reports Server (NTRS)

Holcomb, J. K.

1972-01-01

A summary of the Apollo flights from AS-201 through Apollo 16 is presented. The following subjects are discussed for each flight: (1) mission primary objectives, (2) principle objectives of the launch vehicle and spacecraft, (3) secondary objectives of the launch vehicle and spacecraft, (4) unusual features of the mission, (5) general information on the spacecraft and launch vehicle, (6) space vehicle and pre-launch data, and (7) recovery data.

A squamous odontogenic tumor following an orthodontic micro-screw: A rare case report and review of the literature.

PubMed

Tu, Jingqiu; Yin, Ping; Yuan, Yunyi; Chen, Jie; Yuan, Yongxiang; Lei, Yonghua

2018-02-01

We reported a very rare case of squamous odontogenic tumor(SOT) in a 23-year-old female. The tumor arose after an implanting operation of an orthodontic micro-screw, and was definitely diagnosed by the histopathological examination. Based on the case report and a review of the literature, we discussed about the general features, differential diagnosis and pathogenesis of SOT. Copyright © 2017 Elsevier Ltd. All rights reserved.

The planets of the Solar System

NASA Technical Reports Server (NTRS)

Marov, M. Y.

1986-01-01

This book is intended both for the lay person and the would-be scientist. The planets are discussed with a comparision of their basic natural features: mechanical characteristics and parameters of movement, surfaces, inner structure, physical properties of the atmosphere and meteorology. Also general problems of planetary cosmogony, thermal history and climatic evolution are considered briefly. The book is based on Soviet and foreign material, data from spacecraft, Earth optical and radio astronomical measurements and also data obtained from theoretical models.

Optical Model and Cross Section Uncertainties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herman,M.W.; Pigni, M.T.; Dietrich, F.S.

2009-10-05

Distinct minima and maxima in the neutron total cross section uncertainties were observed in model calculations using spherical optical potential. We found this oscillating structure to be a general feature of quantum mechanical wave scattering. Specifically, we analyzed neutron interaction with 56Fe from 1 keV up to 65 MeV, and investigated physical origin of the minima.We discuss their potential importance for practical applications as well as the implications for the uncertainties in total and absorption cross sections.

A Machine Learning Approach to Discover Rules for Expressive Performance Actions in Jazz Guitar Music.

PubMed

Giraldo, Sergio I; Ramirez, Rafael

2016-01-01

Expert musicians introduce expression in their performances by manipulating sound properties such as timing, energy, pitch, and timbre. Here, we present a data driven computational approach to induce expressive performance rule models for note duration, onset, energy, and ornamentation transformations in jazz guitar music. We extract high-level features from a set of 16 commercial audio recordings (and corresponding music scores) of jazz guitarist Grant Green in order to characterize the expression in the pieces. We apply machine learning techniques to the resulting features to learn expressive performance rule models. We (1) quantitatively evaluate the accuracy of the induced models, (2) analyse the relative importance of the considered musical features, (3) discuss some of the learnt expressive performance rules in the context of previous work, and (4) assess their generailty. The accuracies of the induced predictive models is significantly above base-line levels indicating that the audio performances and the musical features extracted contain sufficient information to automatically learn informative expressive performance patterns. Feature analysis shows that the most important musical features for predicting expressive transformations are note duration, pitch, metrical strength, phrase position, Narmour structure, and tempo and key of the piece. Similarities and differences between the induced expressive rules and the rules reported in the literature were found. Differences may be due to the fact that most previously studied performance data has consisted of classical music recordings. Finally, the rules' performer specificity/generality is assessed by applying the induced rules to performances of the same pieces performed by two other professional jazz guitar players. Results show a consistency in the ornamentation patterns between Grant Green and the other two musicians, which may be interpreted as a good indicator for generality of the ornamentation rules.

A Machine Learning Approach to Discover Rules for Expressive Performance Actions in Jazz Guitar Music

PubMed Central

Giraldo, Sergio I.; Ramirez, Rafael

2016-01-01

Expert musicians introduce expression in their performances by manipulating sound properties such as timing, energy, pitch, and timbre. Here, we present a data driven computational approach to induce expressive performance rule models for note duration, onset, energy, and ornamentation transformations in jazz guitar music. We extract high-level features from a set of 16 commercial audio recordings (and corresponding music scores) of jazz guitarist Grant Green in order to characterize the expression in the pieces. We apply machine learning techniques to the resulting features to learn expressive performance rule models. We (1) quantitatively evaluate the accuracy of the induced models, (2) analyse the relative importance of the considered musical features, (3) discuss some of the learnt expressive performance rules in the context of previous work, and (4) assess their generailty. The accuracies of the induced predictive models is significantly above base-line levels indicating that the audio performances and the musical features extracted contain sufficient information to automatically learn informative expressive performance patterns. Feature analysis shows that the most important musical features for predicting expressive transformations are note duration, pitch, metrical strength, phrase position, Narmour structure, and tempo and key of the piece. Similarities and differences between the induced expressive rules and the rules reported in the literature were found. Differences may be due to the fact that most previously studied performance data has consisted of classical music recordings. Finally, the rules' performer specificity/generality is assessed by applying the induced rules to performances of the same pieces performed by two other professional jazz guitar players. Results show a consistency in the ornamentation patterns between Grant Green and the other two musicians, which may be interpreted as a good indicator for generality of the ornamentation rules. PMID:28066290

Are Social Networking Sites Making Health Behavior Change Interventions More Effective? A Meta-Analytic Review.

PubMed

Yang, Qinghua

2017-03-01

The increasing popularity of social networking sites (SNSs) has drawn scholarly attention in recent years, and a large amount of efforts have been made in applying SNSs to health behavior change interventions. However, these interventions showed mixed results, with a large variance of effect sizes in Cohen's d ranging from -1.17 to 1.28. To provide a better understanding of SNS-based interventions' effectiveness, a meta-analysis of 21 studies examining the effects of health interventions using SNS was conducted. Results indicated that health behavior change interventions using SNS are effective in general, but the effects were moderated by health topic, methodological features, and participant features. Theoretical and practical implications of findings are discussed.

Map showing the association of linear features with metallic mines and prospects in the Butte 1 degree by 2 degrees Quadrangle, Montana

USGS Publications Warehouse

Rowan, L.C.; Trautwein, C.M.; Purdy, T.L.

1990-01-01

This study was undertaken as part of the Conterminous U.S. Mineral Assessment Program (CUSMAP). The purpose of the study was to map linear features on Landsat Multispectral Scanner (MSS) images and a proprietary side-looking airborne radar (SLAR) image mosaic and to determine the spatial relationship between these linear features and the locations of metallic mineral occurrE-nces. The results show a close spatial association of linear features with metallic mineral occurrences in parts of the quadrangle, but in other areas the association is less well defined. Linear features are defined as distinct linear and slightly curvilinear elements mappable on MSS and SLAR images. The features generally represent linear segments of streams, ridges, and terminations of topographic features; however, they may also represent tonal patterns that are related to variations in lithology and vegetation. Most linear features in the Butte quadrangle probably represent underlying structural elements, such as fractures (with and without displacement), dikes, and alignment of fold axes. However, in areas underlain by sedimentary rocks, some of the linear features may reflect bedding traces. This report describes the geologic setting of the Butte quadrangle, the procedures used in mapping and analyzing the linear features, and the results of the study. Relationship of these features to placer and non-metal deposits were not analyzed in this study and are not discussed in this report.

Digital cytology: current state of the art and prospects for the future.

PubMed

Wilbur, David C

2011-01-01

The growth of digital methods in pathology is accelerating. Digital images can be used for a variety of applications in cytology, including rapid interpretations, primary diagnosis and second opinions, continuing education and proficiency testing. All of these functions can be performed using small static digital images, real-time dynamic digital microscopy, or whole-slide images. This review will discuss the general principles of digital pathology, its methods and applications to cytologic specimens. As cytologic specimens have unique features compared to histopathology specimens, the key differences will be discussed. Technical and administrative issues in digital pathology applications and the outlook for the future of the field will be presented. Copyright © 2011 S. Karger AG, Basel.

Three-Dimensional Boundary-Layer program (BL3D) for swept subsonic or supersonic wings with application to laminar flow control

NASA Technical Reports Server (NTRS)

Iyer, Venkit

1993-01-01

The theory, formulation, and solution of three-dimensional, compressible attached laminar flows, applied to swept wings in subsonic or supersonic flow are discussed. Several new features and modifications to an earlier general procedure described in NASA CR 4269, Jan. 1990 are incorporated. Details of interfacing the boundary-layer computation with solution of the inviscid Euler equations are discussed. A description of the computer program, complete with user's manual and example cases, is also included. Comparison of solutions with Navier-Stokes computations with or without boundary-layer suction is given. Output of solution profiles and derivatives required in boundary-layer stability analysis is provided.

Superconducting heavy ion injector linac

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shepard, K.W.

1985-01-01

A conceptual design for a very low velocity (.007 < v/c < .07) superconducting heavy-ion linac is reviewed. This type of linac may have significant cost and performance advantages over room-temperature linacs, at least for applications requiring modest beam currents. Some general features of the design of very-low velocity superconducting accelerating structures are discussed and a design for a 48.5 MHz, v/c = .009 structure, together with the status of a niobium prototype, is discussed in detail. Preliminary results of a beam dynamics study indicate that the low velocity linac may be able to produce heavy-ion beams with time-energy spreadsmore » of a few keV-nsec. 11 refs, 4 figs.« less

Bio-inspired active materials

NASA Astrophysics Data System (ADS)

Fratzl, Peter

Biological tissues are naturally interactive and adaptive. In general, these features are due to the action of cells that provide sensing, actuation as well as tissue remodelling. There are also examples of materials synthesized by living organisms, such as plant seeds, which fulfil an active function without living cells working as mechanosensors and actuators. Thus the activity of these materials is based on physical principles alone, which provides inspiration for new concepts for artificial active materials. We will describe structural principles leading to movement in seed capsules triggered by ambient humidity and discuss the influence of internal architecture on the overall mechanical behaviour of materials, including actuation and motility. Several conceptual systems for actuating planar structures will be discussed.

Superintegrable three-body systems on the line

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chanu, Claudia; Degiovanni, Luca; Rastelli, Giovanni

2008-11-15

We consider classical three-body interactions on a Euclidean line depending on the reciprocal distance of the particles and admitting four functionally independent quadratic in the momentum first integrals. These systems are multiseparable, superintegrable, and equivalent (up to rescalings) to a one-particle system in the three-dimensional Euclidean space. Common features of the dynamics are discussed. We show how to determine quantum symmetry operators associated with the first integrals considered here but do not analyze the corresponding quantum dynamics. The conformal multiseparability is discussed and examples of conformal first integrals are given. The systems considered here in generality include the Calogero, Wolfes,more » and other three-body interactions widely studied in mathematical physics.« less

Data-Driven Significance Estimation for Precise Spike Correlation

PubMed Central

Grün, Sonja

2009-01-01

The mechanisms underlying neuronal coding and, in particular, the role of temporal spike coordination are hotly debated. However, this debate is often confounded by an implicit discussion about the use of appropriate analysis methods. To avoid incorrect interpretation of data, the analysis of simultaneous spike trains for precise spike correlation needs to be properly adjusted to the features of the experimental spike trains. In particular, nonstationarity of the firing of individual neurons in time or across trials, a spike train structure deviating from Poisson, or a co-occurrence of such features in parallel spike trains are potent generators of false positives. Problems can be avoided by including these features in the null hypothesis of the significance test. In this context, the use of surrogate data becomes increasingly important, because the complexity of the data typically prevents analytical solutions. This review provides an overview of the potential obstacles in the correlation analysis of parallel spike data and possible routes to overcome them. The discussion is illustrated at every stage of the argument by referring to a specific analysis tool (the Unitary Events method). The conclusions, however, are of a general nature and hold for other analysis techniques. Thorough testing and calibration of analysis tools and the impact of potentially erroneous preprocessing stages are emphasized. PMID:19129298

Underground waters of eastern United States

USGS Publications Warehouse

Fuller, Myron L.

1905-01-01

The present paper is a brief summary of the underground water conditions in eastern United States, prepared to meet the demands of drillers and others for information relating to the general water resources of the various States or of specified regions.The detail with which the several regions or subjects are discussed depends mainly on their relative importance, although because of the greater amount of work done in certain localities, or on certain problems, it is possible to make more complete and definite statements in regard to the underground water supplies in some regions than in others. The included reports have been prepared by a number of geologists, each, in general, having charge of the investigations in a particular State or group of States. Because of the number of contributors there is necessarily considerable variation in the manner of treatment of the subject, but in most cases the same general plan has been followed.In preparing the paper simplicity of treatment has been kept in mind, and elaborate geologic discussions have been omitted. Wherever possible maps have been given in preference to long and possibly obscure discussions. In some instances, however, it has been necessary to describe the various water-bearing formations under their geologic names. Where this has been necessary the aim has been to employ those terms which are oldest and best known to the people of the States to which the discussion relates.For the purpose of presenting in a simple manner a few of the more important features relating to the nature and occurrence of subterranean waters and of making more intelligible the descriptions of the conditions in the various States, there is given a short paper on the general occurrence of underground waters.

General purpose pulse shape analysis for fast scintillators implemented in digital readout electronics

NASA Astrophysics Data System (ADS)

Asztalos, Stephen J.; Hennig, Wolfgang; Warburton, William K.

2016-01-01

Pulse shape discrimination applied to certain fast scintillators is usually performed offline. In sufficiently high-event rate environments data transfer and storage become problematic, which suggests a different analysis approach. In response, we have implemented a general purpose pulse shape analysis algorithm in the XIA Pixie-500 and Pixie-500 Express digital spectrometers. In this implementation waveforms are processed in real time, reducing the pulse characteristics to a few pulse shape analysis parameters and eliminating time-consuming waveform transfer and storage. We discuss implementation of these features, their advantages, necessary trade-offs and performance. Measurements from bench top and experimental setups using fast scintillators and XIA processors are presented.

Dimensional Reduction for the General Markov Model on Phylogenetic Trees.

PubMed

Sumner, Jeremy G

2017-03-01

We present a method of dimensional reduction for the general Markov model of sequence evolution on a phylogenetic tree. We show that taking certain linear combinations of the associated random variables (site pattern counts) reduces the dimensionality of the model from exponential in the number of extant taxa, to quadratic in the number of taxa, while retaining the ability to statistically identify phylogenetic divergence events. A key feature is the identification of an invariant subspace which depends only bilinearly on the model parameters, in contrast to the usual multi-linear dependence in the full space. We discuss potential applications including the computation of split (edge) weights on phylogenetic trees from observed sequence data.

Complexity-aware simple modeling.

PubMed

Gómez-Schiavon, Mariana; El-Samad, Hana

2018-02-26

Mathematical models continue to be essential for deepening our understanding of biology. On one extreme, simple or small-scale models help delineate general biological principles. However, the parsimony of detail in these models as well as their assumption of modularity and insulation make them inaccurate for describing quantitative features. On the other extreme, large-scale and detailed models can quantitatively recapitulate a phenotype of interest, but have to rely on many unknown parameters, making them often difficult to parse mechanistically and to use for extracting general principles. We discuss some examples of a new approach-complexity-aware simple modeling-that can bridge the gap between the small-scale and large-scale approaches. Copyright © 2018 Elsevier Ltd. All rights reserved.

The dynamics of acute inflammation

NASA Astrophysics Data System (ADS)

Kumar, Rukmini

The acute inflammatory response is the non-specific and immediate reaction of the body to pathogenic organisms, tissue trauma and unregulated cell growth. An imbalance in this response could lead to a condition commonly known as "shock" or "sepsis". This thesis is an attempt to elucidate the dynamics of acute inflammatory response to infection and contribute to its systemic understanding through mathematical modeling and analysis. The models of immunity discussed use Ordinary Differential Equations (ODEs) to model the variation of concentration in time of the various interacting species. Chapter 2 discusses three such models of increasing complexity. Sections 2.1 and 2.2 discuss smaller models that capture the core features of inflammation and offer general predictions concerning the design of the system. Phase-space and bifurcation analyses have been used to examine the behavior at various parameter regimes. Section 2.3 discusses a global physiological model that includes several equations modeling the concentration (or numbers) of cells, cytokines and other mediators. The conclusions drawn from the reduced and detailed models about the qualitative effects of the parameters are very similar and these similarities have also been discussed. In Chapter 3, the specific applications of the biologically detailed model are discussed in greater detail. These include a simulation of anthrax infection and an in silico simulation of a clinical trial. Such simulations are very useful to biologists and could prove to be invaluable tools in drug design. Finally, Chapter 4 discusses the general problem of extinction of populations modeled as continuous variables in ODES is discussed. The average time to extinction and threshold are estimated based on analyzing the equivalent stochastic processes.

Compositional Analyses and Implications of Visible/Near-Infrared Spectra of Outer Irregular Jovian Satellites

NASA Astrophysics Data System (ADS)

Vilas, Faith; Hendrix, Amanda

2017-10-01

The existence of a visible-near infrared absorption feature attributed to aqueous alteration products has been suggested in both grey and reddened broadband photometry of some outer irregular jovian satellites. Moderate resolution VNIR narrowband spectroscopy was obtained of the jovian irregular satellites JVI Himalia, JVII Elara, JVIII Pasiphae, JIX Sinope, JX Lysithea, JXI Carme, JXII Ananke and JXVII Callirrhoe in 2006, 2008, 2009, and 2010 using the MMT Observatory facility Red Channel spectrograph to confirm the presence of this feature. The spectra are centered near 0.64 μm in order to cover the 0.7-μm feature entirely (generally ranging from 0.57 to 0.83 μm). The spectra generally have a dispersion/element of ~0.6 nm (6Å) some spectra are smoothed. These spectra sample three prograde (i = 28o), four retrograde (i = 149o, 165o) and one independent satellite.We observe these findings among the spectra:- An absorption feature centered near 0.7 µm exists in the spectra of the three prograde (i = 28o) satellites. This feature is spectrally broader than the 0.7-µm feature observed in C-complex asteroids. None appears spectrally reddened. This suggests that these prograde satellites have a common parent body.- A different absorption feature appears in the spectra of the three retrograde (i = 149o) satellites, also suggesting a common parent body. Varying reddening is observed. This feature is similar in spectral location and width to the 0.7-µm feature.- Reddening is observed in the individual observation of JXI Carme (i = 165o), and independent satellite JIX Sinope, similar to the D-class asteroid spectra dominating the Trojan population. A suggested absorption feature is being investigated.Mixing modeling of combinations of both expected and proposed compositions including carbonaceous materials, phyllosilicates, mafic silicates, and other opaque materials, is currently underway. Results will be reported and discussed at the meeting.Acknowledgments: The MMT Observatory is a joint facility of the University of Arizona and the Smithsonian Institution. This research has been supported by SSERVI CLASS.

Vectorized Monte Carlo methods for reactor lattice analysis

NASA Technical Reports Server (NTRS)

Brown, F. B.

1984-01-01

Some of the new computational methods and equivalent mathematical representations of physics models used in the MCV code, a vectorized continuous-enery Monte Carlo code for use on the CYBER-205 computer are discussed. While the principal application of MCV is the neutronics analysis of repeating reactor lattices, the new methods used in MCV should be generally useful for vectorizing Monte Carlo for other applications. For background, a brief overview of the vector processing features of the CYBER-205 is included, followed by a discussion of the fundamentals of Monte Carlo vectorization. The physics models used in the MCV vectorized Monte Carlo code are then summarized. The new methods used in scattering analysis are presented along with details of several key, highly specialized computational routines. Finally, speedups relative to CDC-7600 scalar Monte Carlo are discussed.

A hierarchy for modeling high speed propulsion systems

NASA Technical Reports Server (NTRS)

Hartley, Tom T.; Deabreu, Alex

1991-01-01

General research efforts on reduced order propulsion models for control systems design are overviewed. Methods for modeling high speed propulsion systems are discussed including internal flow propulsion systems that do not contain rotating machinery such as inlets, ramjets, and scramjets. The discussion is separated into four sections: (1) computational fluid dynamics model for the entire nonlinear system or high order nonlinear models; (2) high order linearized model derived from fundamental physics; (3) low order linear models obtained from other high order models; and (4) low order nonlinear models. Included are special considerations on any relevant control system designs. The methods discussed are for the quasi-one dimensional Euler equations of gasdynamic flow. The essential nonlinear features represented are large amplitude nonlinear waves, moving normal shocks, hammershocks, subsonic combustion via heat addition, temperature dependent gases, detonation, and thermal choking.

Sickle-cell haemoglobin C disease in London

PubMed Central

Black, A. J.; Condon, P. I.; Gompels, B. M.; Green, R. L.; Huntsman, R. G.; Jenkins, G. C.

1972-01-01

The manifestations of the sickling disorders are becoming increasingly familiar to clinicians in Great Britain. One of these disorders, sickle-cell haemoglobin disease, has hitherto received little attention, being regarded as a relatively mild condition. This paper describes some of the distinctive clinical features of the disease as seen in a series of nine cases which have recently presented in London, two of which were fatal. The special hazards of the condition in relation to pregnancy, air travel, and general anaesthesia are discussed. Images PMID:5015374

A serial digital data communications device. [for real time flight simulation

NASA Technical Reports Server (NTRS)

Fetter, J. L.

1977-01-01

A general purpose computer peripheral device which is used to provide a full-duplex, serial, digital data transmission link between a Xerox Sigma computer and a wide variety of external equipment, including computers, terminals, and special purpose devices is reported. The interface has an extensive set of user defined options to assist the user in establishing the necessary data links. This report describes those options and other features of the serial communications interface and its performance by discussing its application to a particular problem.

Reducing the spectral index in supernatural inflation

NASA Astrophysics Data System (ADS)

Lin, Chia-Min; Cheung, Kingman

2009-04-01

Supernatural inflation is an attractive model based on just a flat direction with soft supersymmetry breaking mass terms in the framework of supersymmetry. The beauty of the model is that it needs no fine-tuning. However, the prediction of the spectral index is ns≳1, in contrast to experimental data. In this paper, we discuss supernatural inflation with the spectral index reduced to ns=0.96 without any fine-tuning, considering the general feature that a flat direction is lifted by a nonrenormalizable term with an A-term.

The Totality App — General Lessons and Future Eclipses

NASA Astrophysics Data System (ADS)

Bennett, Jeffrey

2018-06-01

With the excitement around the 2017 eclipse, I worked with an app development company to create the Totality app, which featured eclipse predictions from the code of Xavier Jubier. We have since updated the app for future eclipses, including a Spanish version given the upcoming eclipses in Chile/Argentina. I will briefly discuss the current app, the process through which we developed it, and relevant lessons learned along the way that may be useful to others interested in developing apps for astronomy education.

Three-dimensional viscous design methodology for advanced technology aircraft supersonic inlet systems

NASA Technical Reports Server (NTRS)

Anderson, B. H.

1983-01-01

A broad program to develop advanced, reliable, and user oriented three-dimensional viscous design techniques for supersonic inlet systems, and encourage their transfer into the general user community is discussed. Features of the program include: (1) develop effective methods of computing three-dimensional flows within a zonal modeling methodology; (2) ensure reasonable agreement between said analysis and selective sets of benchmark validation data; (3) develop user orientation into said analysis; and (4) explore and develop advanced numerical methodology.

The uncertainty principle and quantum chaos

NASA Technical Reports Server (NTRS)

Chirikov, Boris V.

1993-01-01

The conception of quantum chaos is described in some detail. The most striking feature of this novel phenomenon is that all the properties of classical dynamical chaos persist here but, typically, on the finite and different time scales only. The ultimate origin of such a universal quantum stability is in the fundamental uncertainty principle which makes discrete the phase space and, hence, the spectrum of bounded quantum motion. Reformulation of the ergodic theory, as a part of the general theory of dynamical systems, is briefly discussed.

The { β}-expansion formalism in perturbative QCD and its extension

NASA Astrophysics Data System (ADS)

Kataev, A. L.; Mikhailov, S. V.

2016-11-01

We discuss the { β}-expansion for renormalization group invariant quantities tracing this expansion to the different contractions of the corresponding incomplete BPHZ R-operation. All of the coupling renormalizations, which follow from these contractions, should be taken into account for the { β}-expansion. We illustrate this feature considering the nonsinglet Adler function D NS in the third order of perturbation. We propose a generalization of the { β}-expansion for the renormalization group covariant quantities — the { β, γ}-expansion.

Frequency Dependence of Single-event Upset in Advanced Commerical PowerPC Microprocessors

NASA Technical Reports Server (NTRS)

Irom, Frokh; Farmanesh, Farhad F.; Swift, Gary M.; Johnston, Allen H.

2004-01-01

This paper examines single-event upsets in advanced commercial SOI microprocessors in a dynamic mode, studying SEU sensitivity of General Purpose Registers (GPRs) with clock frequency. Results are presented for SOI processors with feature sizes of 0.18 microns and two different core voltages. Single-event upset from heavy ions is measured for advanced commercial microprocessors in a dynamic mode with clock frequency up to 1GHz. Frequency and core voltage dependence of single-event upsets in registers is discussed.

Instantaneous Assessment Of Athletic Performance Using High Speed Video

NASA Astrophysics Data System (ADS)

Hubbard, Mont; Alaways, LeRoy W.

1988-02-01

We describe the use of high speed video to provide quantitative assessment of motion in athletic performance. Besides the normal requirement for accuracy, an essential feature is that the information be provided rapidly enough so that it my serve as valuable feedback in the learning process. The general considerations which must be addressed in the development of such a computer based system are discussed. These ideas are illustrated specifically through the description of a prototype system which has been designed for the javelin throw.

Multi-modal data fusion using source separation: Two effective models based on ICA and IVA and their properties

PubMed Central

Adali, Tülay; Levin-Schwartz, Yuri; Calhoun, Vince D.

2015-01-01

Fusion of information from multiple sets of data in order to extract a set of features that are most useful and relevant for the given task is inherent to many problems we deal with today. Since, usually, very little is known about the actual interaction among the datasets, it is highly desirable to minimize the underlying assumptions. This has been the main reason for the growing importance of data-driven methods, and in particular of independent component analysis (ICA) as it provides useful decompositions with a simple generative model and using only the assumption of statistical independence. A recent extension of ICA, independent vector analysis (IVA) generalizes ICA to multiple datasets by exploiting the statistical dependence across the datasets, and hence, as we discuss in this paper, provides an attractive solution to fusion of data from multiple datasets along with ICA. In this paper, we focus on two multivariate solutions for multi-modal data fusion that let multiple modalities fully interact for the estimation of underlying features that jointly report on all modalities. One solution is the Joint ICA model that has found wide application in medical imaging, and the second one is the the Transposed IVA model introduced here as a generalization of an approach based on multi-set canonical correlation analysis. In the discussion, we emphasize the role of diversity in the decompositions achieved by these two models, present their properties and implementation details to enable the user make informed decisions on the selection of a model along with its associated parameters. Discussions are supported by simulation results to help highlight the main issues in the implementation of these methods. PMID:26525830

Understanding egorrhea from cultural-clinical psychology

PubMed Central

Sasaki, Jun; Wada, Kaori; Tanno, Yoshihiko

2013-01-01

Based on his observations in Japanese clinical settings, Fujinawa (1972) conceptualized egorrhea syndrome, which includes symptoms such as erythrophobia, fear of eye-to-eye confrontation, olfactory reference syndrome, delusions of soliloquy, delusions of sleep talking, and thought broadcasting. The key feature of this syndrome is self-leakage, a perceived sense that one's personal internal information, such as feelings and thoughts, are leaking out. To reach a more comprehensive understanding of egorrhea, this paper aims to present general overview and reconsider the phenomenon of self-leakage using cultural-clinical psychology as a framework. First, the symptoms of egorrhea are reviewed in relation to other related psychopathologies such as social anxiety disorder (SAD) and taijin kyofusho (TKS), as well as schizophrenia. Second, a series of empirical studies conducted using Japanese non-clinical samples are summarized. The results of these studies form the basis for subsequent discussions, which incorporates the cultural-clinical psychology perspective proposed by Ryder et al. (2011). This paper ends with a general discussion regarding implications for research and clinical practice. PMID:24348445

How to be smart and energy efficient: A general discussion on thermochromic windows

PubMed Central

Long, Linshuang; Ye, Hong

2014-01-01

A window is a unique element in a building because of its simultaneous properties of being “opaque” to inclement weather yet transparent to the observer. However, these unique features make the window an element that can reduce the energy efficiency of buildings. A thermochromic window is a type of smart window whose solar radiation properties vary with temperature. It is thought that the solar radiation gain of a room can be intelligently regulated through the use of thermochromic windows, resulting in lower energy consumption than with standard windows. Materials scientists have made many efforts to improve the performance of thermochromic materials. Despite these efforts, fundamental problems continue to confront us. How should a “smart” window behave? Is a “smart” window really the best candidate for energy-efficient applications? What is the relationship between smartness and energy performance? To answer these questions, a general discussion of smartness and energy performance is provided. PMID:25233891

Criticism of generally accepted fundamentals and methodologies of traffic and transportation theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kerner, Boris S.

It is explained why the set of the fundamental empirical features of traffic breakdown (a transition from free flow to congested traffic) should be the empirical basis for any traffic and transportation theory that can be reliable used for control and optimization in traffic networks. It is shown that generally accepted fundamentals and methodologies of traffic and transportation theory are not consistent with the set of the fundamental empirical features of traffic breakdown at a highway bottleneck. To these fundamentals and methodologies of traffic and transportation theory belong (i) Lighthill-Whitham-Richards (LWR) theory, (ii) the General Motors (GM) model class (formore » example, Herman, Gazis et al. GM model, Gipps’s model, Payne’s model, Newell’s optimal velocity (OV) model, Wiedemann’s model, Bando et al. OV model, Treiber’s IDM, Krauß’s model), (iii) the understanding of highway capacity as a particular stochastic value, and (iv) principles for traffic and transportation network optimization and control (for example, Wardrop’s user equilibrium (UE) and system optimum (SO) principles). Alternatively to these generally accepted fundamentals and methodologies of traffic and transportation theory, we discuss three-phase traffic theory as the basis for traffic flow modeling as well as briefly consider the network breakdown minimization (BM) principle for the optimization of traffic and transportation networks with road bottlenecks.« less

Pulmonary nodule characterization, including computer analysis and quantitative features.

PubMed

Bartholmai, Brian J; Koo, Chi Wan; Johnson, Geoffrey B; White, Darin B; Raghunath, Sushravya M; Rajagopalan, Srinivasan; Moynagh, Michael R; Lindell, Rebecca M; Hartman, Thomas E

2015-03-01

Pulmonary nodules are commonly detected in computed tomography (CT) chest screening of a high-risk population. The specific visual or quantitative features on CT or other modalities can be used to characterize the likelihood that a nodule is benign or malignant. Visual features on CT such as size, attenuation, location, morphology, edge characteristics, and other distinctive "signs" can be highly suggestive of a specific diagnosis and, in general, be used to determine the probability that a specific nodule is benign or malignant. Change in size, attenuation, and morphology on serial follow-up CT, or features on other modalities such as nuclear medicine studies or MRI, can also contribute to the characterization of lung nodules. Imaging analytics can objectively and reproducibly quantify nodule features on CT, nuclear medicine, and magnetic resonance imaging. Some quantitative techniques show great promise in helping to differentiate benign from malignant lesions or to stratify the risk of aggressive versus indolent neoplasm. In this article, we (1) summarize the visual characteristics, descriptors, and signs that may be helpful in management of nodules identified on screening CT, (2) discuss current quantitative and multimodality techniques that aid in the differentiation of nodules, and (3) highlight the power, pitfalls, and limitations of these various techniques.

Titan's surface from Cassini RADAR SAR and high resolution radiometry data of the first five flybys

USGS Publications Warehouse

Paganelli, F.; Janssen, M.A.; Stiles, B.; West, R.; Lorenz, R.D.; Lunine, J.I.; Wall, S.D.; Callahan, P.; Lopes, R.M.; Stofan, E.; Kirk, R.L.; Johnson, W.T.K.; Roth, L.; Elachi, C.; ,

2007-01-01

The first five Titan flybys with Cassini's Synthetic Aperture RADAR (SAR) and radiometer are examined with emphasis on the calibration and interpretation of the high-resolution radiometry data acquired during the SAR mode (SAR-radiometry). Maps of the 2-cm wavelength brightness temperature are obtained coincident with the SAR swath imaging, with spatial resolution approaching 6 km. A preliminary calibration shows that brightness temperature in these maps varies from 64 to 89 K. Surface features and physical properties derived from the SAR-radiometry maps and SAR imaging are strongly correlated; in general, we find that surface features with high radar reflectivity are associated with radiometrically cold regions, while surface features with low radar reflectivity correlate with radiometrically warm regions. We examined scatterplots of the normalized radar cross-section ??0 versus brightness temperature, finding differing signatures that characterize various terrains and surface features. Implications for the physical and compositional properties of these features are discussed. The results indicate that volume scattering is important in many areas of Titan's surface, particularly Xanadu, while other areas exhibit complex brightness temperature variations consistent with variable slopes or surface material and compositional properties. ?? 2007 Elsevier Inc.

Usability issues concerning child restraint system harness design.

PubMed

Rudin-Brown, Christina M; Kumagai, Jason K; Angel, Harry A; Iwasa-Madge, Kim M; Noy, Y Ian

2003-05-01

A study was conducted to assess usability issues relating to child restraint system (CRS) harness design. Four convertible child restraint systems representing a wide variety of design features were used. Forty-two participants installed two child test dummies in both forward- and rear-facing configurations either inside or outside a test vehicle. Observer-scored checklists determined the degree to which each harness was installed correctly. Participant-scored questionnaires evaluated the 'ease-of-use' of various design features. While the percentage of correct installations exceeded 83% for all designs when installed in the forward-facing configuration, in the rear-facing position (that intended for children under 9-10 kg), there was a significant (between 65 and 89%) percentage of incorrect installations for all models. This finding is of particular interest and may be indicative of a more generalized problem with 'convertible' CRS designs when they are used in the rear-facing configuration. Furthermore, while certain design features were perceived by users as providing significantly better protection in the event of a collision, these also tended to be the features that were misused most often. The benefits and costs of various design features are discussed, and a method to test harness design usability is presented.

Miniscrews for orthodontic anchorage: a review of available systems.

PubMed

Alkadhimi, Aslam; Al-Awadhi, Ebrahim A

2018-03-15

In recent years, extensive research has introduced novel ways of reinforcing orthodontic anchorage using a variety of devices temporarily anchored in bone (miniscrews). Currently, there are numerous manufacturers with different miniscrew designs on the market. The aim of this paper is to discuss the key design features of different miniscrew systems on the market. Furthermore, to present clinical selection criteria of miniscrews in different settings taking into account the determinant factors. Review of the literature was carried out using the following search methods: MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL). The search was focused on studies published until January 2018. We studied each individual miniscrew from all the identified manufacturers in details. All the features were then summarised and presented as a clinical guideline for the selection of miniscrews. In this article, we reviewed the development of miniscrews and outlined the general design features of miniscrews as well as specific design features of the current miniscrews in the market. Extensive research of the current products was carried out to help clinicians better understand the difference between the various designs of miniscrews that can be used.

CNN-SVM for Microvascular Morphological Type Recognition with Data Augmentation.

PubMed

Xue, Di-Xiu; Zhang, Rong; Feng, Hui; Wang, Ya-Lei

2016-01-01

This paper focuses on the problem of feature extraction and the classification of microvascular morphological types to aid esophageal cancer detection. We present a patch-based system with a hybrid SVM model with data augmentation for intraepithelial papillary capillary loop recognition. A greedy patch-generating algorithm and a specialized CNN named NBI-Net are designed to extract hierarchical features from patches. We investigate a series of data augmentation techniques to progressively improve the prediction invariance of image scaling and rotation. For classifier boosting, SVM is used as an alternative to softmax to enhance generalization ability. The effectiveness of CNN feature representation ability is discussed for a set of widely used CNN models, including AlexNet, VGG-16, and GoogLeNet. Experiments are conducted on the NBI-ME dataset. The recognition rate is up to 92.74% on the patch level with data augmentation and classifier boosting. The results show that the combined CNN-SVM model beats models of traditional features with SVM as well as the original CNN with softmax. The synthesis results indicate that our system is able to assist clinical diagnosis to a certain extent.

Myopathy in Childhood Muscle-Specific Kinase Myasthenia Gravis.

PubMed

Kirzinger, Lukas; Khomenko, Andrei; Schulte-Mattler, Wilhelm; Backhaus, Roland; Platen, Sabine; Schalke, Berthold

2016-12-01

Adult and pediatric patients suffering from MuSK (muscle-specific kinase) -antibody positive myasthenia gravis exhibit similar features to individuals with acetylcholine receptor (AChR) antibodies, but they differ in several characteristics such as a predominant bulbar, respiratory and neck weakness, a generally worse disease severity and a tendency to develop muscle atrophy. Muscle atrophy is a rare phenomenon that is usually restricted to the facial muscles. We describe a girl with MuSK-antibody positive myasthenia gravis who developed a myopathy with severe generalized muscular weakness, muscle atrophy, and myopathic changes on electromyography. This is the first published example of a generalized myopathic syndrome in myasthenia gravis. We review the relevant literature and discuss the hypothesis of a mitochondrial myopathy as a pathogenic mechanism in MuSK-antibody positive myasthenia gravis. Copyright © 2016 Elsevier Inc. All rights reserved.

Clarifying the Dynamics of the General Circulation: Phillips's 1956 Experiment.

NASA Astrophysics Data System (ADS)

Lewis, John M.

1998-01-01

In the mid-1950s, amid heated debate over the physical mechanisms that controlled the known features of the atmosphere's general circulation, Norman Phillips simulated hemispheric motion on the high-speed computer at the Institute for Advanced Study. A simple energetically consistent model was integrated for a simulated time of approximately 1 month. Analysis of the model results clarified the respective roles of the synoptic-scale eddies (cyclones-anticyclones) and mean meridional circulation in the maintenance of the upper-level westerlies and the surface wind regimes. Furthermore, the modeled cyclones clearly linked surface frontogenesis with the upper-level Charney-Eady wave. In addition to discussing the model results in light of the controversy and ferment that surrounded general circulation theory in the 1940s-1950s, an effort is made to follow Phillips's scientific path to the experiment.

Modeling listeners' emotional response to music.

PubMed

Eerola, Tuomas

2012-10-01

An overview of the computational prediction of emotional responses to music is presented. Communication of emotions by music has received a great deal of attention during the last years and a large number of empirical studies have described the role of individual features (tempo, mode, articulation, timbre) in predicting the emotions suggested or invoked by the music. However, unlike the present work, relatively few studies have attempted to model continua of expressed emotions using a variety of musical features from audio-based representations in a correlation design. The construction of the computational model is divided into four separate phases, with a different focus for evaluation. These phases include the theoretical selection of relevant features, empirical assessment of feature validity, actual feature selection, and overall evaluation of the model. Existing research on music and emotions and extraction of musical features is reviewed in terms of these criteria. Examples drawn from recent studies of emotions within the context of film soundtracks are used to demonstrate each phase in the construction of the model. These models are able to explain the dominant part of the listeners' self-reports of the emotions expressed by music and the models show potential to generalize over different genres within Western music. Possible applications of the computational models of emotions are discussed. Copyright © 2012 Cognitive Science Society, Inc.

Identifying marker genes in transcription profiling data using a mixture of feature relevance experts.

PubMed

Chow, M L; Moler, E J; Mian, I S

2001-03-08

Transcription profiling experiments permit the expression levels of many genes to be measured simultaneously. Given profiling data from two types of samples, genes that most distinguish the samples (marker genes) are good candidates for subsequent in-depth experimental studies and developing decision support systems for diagnosis, prognosis, and monitoring. This work proposes a mixture of feature relevance experts as a method for identifying marker genes and illustrates the idea using published data from samples labeled as acute lymphoblastic and myeloid leukemia (ALL, AML). A feature relevance expert implements an algorithm that calculates how well a gene distinguishes samples, reorders genes according to this relevance measure, and uses a supervised learning method [here, support vector machines (SVMs)] to determine the generalization performances of different nested gene subsets. The mixture of three feature relevance experts examined implement two existing and one novel feature relevance measures. For each expert, a gene subset consisting of the top 50 genes distinguished ALL from AML samples as completely as all 7,070 genes. The 125 genes at the union of the top 50s are plausible markers for a prototype decision support system. Chromosomal aberration and other data support the prediction that the three genes at the intersection of the top 50s, cystatin C, azurocidin, and adipsin, are good targets for investigating the basic biology of ALL/AML. The same data were employed to identify markers that distinguish samples based on their labels of T cell/B cell, peripheral blood/bone marrow, and male/female. Selenoprotein W may discriminate T cells from B cells. Results from analysis of transcription profiling data from tumor/nontumor colon adenocarcinoma samples support the general utility of the aforementioned approach. Theoretical issues such as choosing SVM kernels and their parameters, training and evaluating feature relevance experts, and the impact of potentially mislabeled samples on marker identification (feature selection) are discussed.

Skeletal Morphology of Opius dissitus and Biosteres carbonarius (Hymenoptera: Braconidae), with a Discussion of Terminology

PubMed Central

Karlsson, Dave; Ronquist, Fredrik

2012-01-01

The Braconidae, a family of parasitic wasps, constitute a major taxonomic challenge with an estimated diversity of 40,000 to 120,000 species worldwide, only 18,000 of which have been described to date. The skeletal morphology of braconids is still not adequately understood and the terminology is partly idiosyncratic, despite the fact that anatomical features form the basis for most taxonomic work on the group. To help address this problem, we describe the external skeletal morphology of Opius dissitus Muesebeck 1963 and Biosteres carbonarius Nees 1834, two diverse representatives of one of the least known and most diverse braconid subfamilies, the Opiinae. We review the terminology used to describe skeletal features in the Ichneumonoidea in general and the Opiinae in particular, and identify a list of recommend terms, which are linked to the online Hymenoptera Anatomy Ontology. The morphology of the studied species is illustrated with SEM-micrographs, photos and line drawings. Based on the examined species, we discuss intraspecific and interspecific morphological variation in the Opiinae and point out character complexes that merit further study. PMID:22558068

Skeletal morphology of Opius dissitus and Biosteres carbonarius (Hymenoptera: Braconidae), with a discussion of terminology.

PubMed

Karlsson, Dave; Ronquist, Fredrik

2012-01-01

The Braconidae, a family of parasitic wasps, constitute a major taxonomic challenge with an estimated diversity of 40,000 to 120,000 species worldwide, only 18,000 of which have been described to date. The skeletal morphology of braconids is still not adequately understood and the terminology is partly idiosyncratic, despite the fact that anatomical features form the basis for most taxonomic work on the group. To help address this problem, we describe the external skeletal morphology of Opius dissitus Muesebeck 1963 and Biosteres carbonarius Nees 1834, two diverse representatives of one of the least known and most diverse braconid subfamilies, the Opiinae. We review the terminology used to describe skeletal features in the Ichneumonoidea in general and the Opiinae in particular, and identify a list of recommend terms, which are linked to the online Hymenoptera Anatomy Ontology. The morphology of the studied species is illustrated with SEM-micrographs, photos and line drawings. Based on the examined species, we discuss intraspecific and interspecific morphological variation in the Opiinae and point out character complexes that merit further study.

Evolutionary potential games on lattices

NASA Astrophysics Data System (ADS)

Szabó, György; Borsos, István

2016-04-01

Game theory provides a general mathematical background to study the effect of pair interactions and evolutionary rules on the macroscopic behavior of multi-player games where players with a finite number of strategies may represent a wide scale of biological objects, human individuals, or even their associations. In these systems the interactions are characterized by matrices that can be decomposed into elementary matrices (games) and classified into four types. The concept of decomposition helps the identification of potential games and also the evaluation of the potential that plays a crucial role in the determination of the preferred Nash equilibrium, and defines the Boltzmann distribution towards which these systems evolve for suitable types of dynamical rules. This survey draws parallel between the potential games and the kinetic Ising type models which are investigated for a wide scale of connectivity structures. We discuss briefly the applicability of the tools and concepts of statistical physics and thermodynamics. Additionally the general features of ordering phenomena, phase transitions and slow relaxations are outlined and applied to evolutionary games. The discussion extends to games with three or more strategies. Finally we discuss what happens when the system is weakly driven out of the "equilibrium state" by adding non-potential components representing games of cyclic dominance.

TOKEN REINFORCEMENT: A REVIEW AND ANALYSIS

PubMed Central

Hackenberg, Timothy D

2009-01-01

Token reinforcement procedures and concepts are reviewed and discussed in relation to general principles of behavior. The paper is divided into four main parts. Part I reviews and discusses previous research on token systems in relation to common behavioral functions—reinforcement, temporal organization, antecedent stimulus functions, and aversive control—emphasizing both the continuities with other contingencies and the distinctive features of token systems. Part II describes the role of token procedures in the symmetrical law of effect, the view that reinforcers (gains) and punishers (losses) can be measured in conceptually analogous terms. Part III considers the utility of token reinforcement procedures in cross-species analysis of behavior more generally, showing how token procedures can be used to bridge the methodological gulf separating research with humans from that with other animals. Part IV discusses the relevance of token systems to the field of behavioral economics. Token systems have the potential to significantly advance research and theory in behavioral economics, permitting both a more refined analysis of the costs and benefits underlying standard economic models, and a common currency more akin to human monetary systems. Some implications for applied research and for broader theoretical integration across disciplines will also be considered. PMID:19794838

Topographic attributes as a guide for automated detection or highlighting of geological features

NASA Astrophysics Data System (ADS)

Viseur, Sophie; Le Men, Thibaud; Guglielmi, Yves

2015-04-01

Photogrammetry or LIDAR technology combined with photography allow geoscientists to obtain 3D high-resolution numerical representations of outcrops, generally termed as Digital Outcrop Models (DOM). For over a decade, these 3D numerical outcrops serve as support for precise and accurate interpretations of geological features such as fracture traces or plans, strata, facies mapping, etc. These interpretations have the benefit to be directly georeferenced and embedded into the 3D space. They are then easily integrated into GIS or geomodeler softwares for modelling in 3D the subsurface geological structures. However, numerical outcrops generally represent huge data sets that are heavy to manipulate and hence to interpret. This may be particularly tedious as soon as several scales of geological features must be investigated or as geological features are very dense and imbricated. Automated tools for interpreting geological features from DOMs would be then a significant help to process these kinds of data. Such technologies are commonly used for interpreting seismic or medical data. However, it may be noticed that even if many efforts have been devoted to easily and accurately acquire 3D topographic point clouds and photos and to visualize accurate 3D textured DOMs, few attentions have been paid to the development of algorithms for automated detection of the geological structures from DOMs. The automatic detection of objects on numerical data generally assumes that signals or attributes computed from this data allows the recognition of the targeted object boundaries. The first step consists then in defining attributes that highlight the objects or their boundaries. For DOM interpretations, some authors proposed to use differential operators computed on the surface such as normal or curvatures. These methods generally extract polylines corresponding to fracture traces or bed limits. Other approaches rely on the PCA technology to segregate different topographic plans. This approach assume that structural or sedimentary features coincide with topographic surface parts. In this work, several topographic attributes are proposed to highlight geological features on outcrops. Among them, differential operators are used but also combined and processed to display particular topographic shapes. Moreover, two kinds of attributes are used: unsupervised and supervised attributes. The supervised attributes integrate an a priori knowledge about the objects to extract (e.g.: a preferential orientation of fracture surfaces, etc.). This strategy may be compared to the one used for seismic interpretation. Indeed, many seismic attributes have been proposed to highlight geological structures hardly observable due to data noise. The same issue exist with topographic data: plants, erosions, etc. generate noise that make interpretation sometimes hard. The proposed approach has been applied on real case studies to show how it could help the interpretation of geological features. The obtained 'topographic attributes' are shown and discussed.

A reference architecture for the component factory

NASA Technical Reports Server (NTRS)

Basili, Victor R.; Caldiera, Gianluigi; Cantone, Giovanni

1992-01-01

Software reuse can be achieved through an organization that focuses on utilization of life cycle products from previous developments. The component factory is both an example of the more general concepts of experience and domain factory and an organizational unit worth being considered independently. The critical features of such an organization are flexibility and continuous improvement. In order to achieve these features we can represent the architecture of the factory at different levels of abstraction and define a reference architecture from which specific architectures can be derived by instantiation. A reference architecture is an implementation and organization independent representation of the component factory and its environment. The paper outlines this reference architecture, discusses the instantiation process, and presents some examples of specific architectures by comparing them in the framework of the reference model.

Impact Of Resolving Submesoscale Features On Modeling The Gulf Stream System

NASA Astrophysics Data System (ADS)

Chassignet, E.; Xu, X.

2016-02-01

Despite being one the best-known circulation pattern of the world ocean, the representation of the Gulf Stream, especially its energetic extension east of the New England Seamounts Chains in the western North Atlantic Ocean, has been a major challenge for ocean general circulation models even at eddy-rich resolutions. Here we show that, for the first time, a simulation of the North Atlantic circulation at 1/50° resolution realistically represents the narrow, energetic jet near 55°W when compared to observations, whereas similarly configured simulations at 1/25° and 1/12° resolution do not. This result highlights the importance of submesoscale features in driving the energetic Gulf Stream extension in the western North Atlantic. The results are discussed in terms of mesoscale and submesoscale energy power spectra.

Elastic properties of uniaxial-fiber reinforced composites - General features

NASA Astrophysics Data System (ADS)

Datta, Subhendu; Ledbetter, Hassel; Lei, Ming

The salient features of the elastic properties of uniaxial-fiber-reinforced composites are examined by considering the complete set of elastic constants of composites comprising isotropic uniaxial fibers in an isotropic matrix. Such materials exhibit transverse-isotropic symmetry and five independent elastic constants in Voigt notation: C(11), C(33), C(44), C(66), and C(13). These C(ij) constants are calculated over the entire fiber-volume-fraction range 0.0-1.0, using a scattered-plane-wave ensemple-average model. Some practical elastic constants such as the principal Young moduli and the principal Poisson ratios are considered, and the behavior of these constants is discussed. Also presented are the results for the four principal sound velocities used to study uniaxial-fiber-reinforced composites: v(11), v(33), v(12), and v(13).

QCGAT aircraft/engine design for reduced noise and emissions

NASA Technical Reports Server (NTRS)

Lanson, L.; Terrill, K. M.

1980-01-01

The high bypass ratio QCGAT engine played an important role in shaping the aircraft design. The aircraft which evolved is a sleek, advanced design, six-place aircraft with 3538 kg (7,800 lb) maximum gross weight. It offers a 2778 kilometer (1500 nautical mile) range with cruise speed of 0.5 Mach number and will take-off and land on the vast majority of general aviation airfields. Advanced features include broad application of composite materials and a supercritical wing design with winglets. Full-span fowler flaps were introduced to improve landing capability. Engines are fuselage-mounted with inlets over the wing to provide shielding of fan noise by the wing surfaces. The design objectives, noise, and emission considerations, engine cycle and engine description are discussed as well as specific design features.

Quantum Dynamics in the HMF Model

NASA Astrophysics Data System (ADS)

Plestid, Ryan; O'Dell, Duncan

2017-04-01

The Hamiltonian Mean Field (HMF) model represents a paradigm in the study of long-range interactions but has never been realized in a lab. Recently Shutz and Morigi (PRL 113) have come close but ultimately fallen short. Their proposal relied on cavity-induced interactions between atoms. If a design using cold atoms is to be successful, an understanding of quantum effects is essential. I will outline the natural quantum generalization of the HMF assuming a BEC by using a generalized Gross-Pitaevskii equation (gGPE). I will show how quantum effects modify features which are well understood in the classical model. More specifically, by working in the semi-classical regime (strong interparticle interactions) we can identify the universal features predicted by catastrophe theory dressed with quantum interference effects. The stationary states of gGPE can be solved exactly and are found to be described by self-consistent Mathieu functions. Finally, I will discuss the connection between the classical description of the dynamics in terms of the Vlassov equation, and the gGPE. We would like to thank the Government of Ontario's OGS program, NSERC, and the Perimeter Institute of Theoretical Physics.

The evolution of plant-insect mutualisms.

PubMed

Bronstein, Judith L; Alarcón, Ruben; Geber, Monica

2006-01-01

Mutualisms (cooperative interactions between species) have had a central role in the generation and maintenance of life on earth. Insects and plants are involved in diverse forms of mutualism. Here we review evolutionary features of three prominent insect-plant mutualisms: pollination, protection and seed dispersal. We focus on addressing five central phenomena: evolutionary origins and maintenance of mutualism; the evolution of mutualistic traits; the evolution of specialization and generalization; coevolutionary processes; and the existence of cheating. Several features uniting very diverse insect-plant mutualisms are identified and their evolutionary implications are discussed: the involvement of one mobile and one sedentary partner; natural selection on plant rewards; the existence of a continuum from specialization to generalization; and the ubiquity of cheating, particularly on the part of insects. Plant-insect mutualisms have apparently both arisen and been lost repeatedly. Many adaptive hypotheses have been proposed to explain these transitions, and it is unlikely that any one of them dominates across interactions differing so widely in natural history. Evolutionary theory has a potentially important, but as yet largely unfilled, role to play in explaining the origins, maintenance, breakdown and evolution of insect-plant mutualisms.

Toward a clarification of the taxonomy of "bias" in epidemiology textbooks.

PubMed

Schwartz, Sharon; Campbell, Ulka B; Gatto, Nicolle M; Gordon, Kirsha

2015-03-01

Epidemiology textbooks typically divide biases into 3 general categories-confounding, selection bias, and information bias. Despite the ubiquity of this categorization, authors often use these terms to mean different things. This hinders communication among epidemiologists and confuses students who are just learning about the field. To understand the sources of this problem, we reviewed current general epidemiology textbooks to examine how the authors defined and categorized biases. We found that much of the confusion arises from different definitions of "validity" and from a mixing of 3 overlapping organizational features in defining and differentiating among confounding, selection bias, and information bias: consequence, the result of the problem; cause, the processes that give rise to the problem; and cure, how these biases can be addressed once they occur. By contrast, a consistent taxonomy would provide (1) a clear and consistent definition of what unites confounding, selection bias, and information bias and (2) a clear articulation and consistent application of the feature that distinguishes these categories. Based on a distillation of these textbook discussions, we provide an example of a taxonomy that we think meets these criteria.

A Generalization Strategy for Discrete Area Feature by Using Stroke Grouping and Polarization Transportation Selection

NASA Astrophysics Data System (ADS)

Wang, Xiao; Burghardt, Dirk

2018-05-01

This paper presents a new strategy for the generalization of discrete area features by using stroke grouping method and polarization transportation selection. The mentioned stroke is constructed on derive of the refined proximity graph of area features, and the refinement is under the control of four constraints to meet different grouping requirements. The area features which belong to the same stroke are detected into the same group. The stroke-based strategy decomposes the generalization process into two sub-processes by judging whether the area features related to strokes or not. For the area features which belong to the same one stroke, they normally present a linear like pat-tern, and in order to preserve this kind of pattern, typification is chosen as the operator to implement the generalization work. For the remaining area features which are not related by strokes, they are still distributed randomly and discretely, and the selection is chosen to conduct the generalization operation. For the purpose of retaining their original distribution characteristic, a Polarization Transportation (PT) method is introduced to implement the selection operation. Buildings and lakes are selected as the representatives of artificial area feature and natural area feature respectively to take the experiments. The generalized results indicate that by adopting this proposed strategy, the original distribution characteristics of building and lake data can be preserved, and the visual perception is pre-served as before.

Nature of the Congested Traffic and Quasi-steady States of the General Motor Models

NASA Astrophysics Data System (ADS)

Yang, Bo; Xu, Xihua; Pang, John Z. F.; Monterola, Christopher

2015-03-01

We look at the general motor (GM) class microscopic traffic models and analyze some of the universal features of the (multi-)cluster solutions, including the emergence of an intrinsic scale and the quasisoliton dynamics. We show that the GM models can capture the essential physics of the real traffic dynamics, especially the phase transition from the free flow to the congested phase, from which the wide moving jams emerges (the F-S-J transition pioneered by B.S. Kerner). In particular, the congested phase can be associated with either the multi-cluster quasi-steady states, or their more homogeneous precursor states. In both cases the states can last for a long time, and the narrow clusters will eventually grow and merge, leading to the formation of the wide moving jams. We present a general method to fit the empirical parameters so that both quantitative and qualitative macroscopic empirical features can be reproduced with a minimal GM model. We present numerical results for the traffic dynamics both with and without the bottleneck, including various types of spontaneous and induced ``synchronized flow,'' as well as the evolution of wide moving jams. We also discuss its implications to the nature of different phases in traffic dynamics.

Twisted waves and instabilities in a permeating dusty plasma

NASA Astrophysics Data System (ADS)

Bukhari, S.; Ali, S.; Khan, S. A.; Mendonca, J. T.

2018-04-01

New features of the twisted dusty plasma modes and associated instabilities are investigated in permeating plasmas. Using the Vlasov-Poisson model equations, a generalized dispersion relation is obtained for a Maxwellian distributed plasma to analyse the dust-acoustic and dust-ion-acoustic waves with finite orbital angular momentum (OAM) states. Existence conditions for damping/growth rates are discussed and showed significant modifications in twisted dusty modes as compared to straight propagating dusty modes. Numerically, the instability growth rate, which depends on particle streaming and twist effects in the wave potential, is significantly modified due to the Laguerre-Gaussian profiles. Relevance of the study to wave excitations due to penetration of solar wind into cometary clouds or interstellar dusty plasmas is discussed.

How to Modify (Implicit) Evaluations of Fear-Related Stimuli: Effects of Feature-Specific Attention Allocation

PubMed Central

Vanaelst, Jolien; Spruyt, Adriaan; De Houwer, Jan

2016-01-01

We demonstrate that feature-specific attention allocation influences the way in which repeated exposure modulates implicit and explicit evaluations toward fear-related stimuli. During an exposure procedure, participants were encouraged to assign selective attention either to the evaluative meaning (i.e., Evaluative Condition) or a non-evaluative, semantic feature (i.e., Semantic Condition) of fear-related stimuli. The influence of the exposure procedure was captured by means of a measure of implicit evaluation, explicit evaluative ratings, and a measure of automatic approach/avoidance tendencies. As predicted, the implicit measure of evaluation revealed a reduced expression of evaluations in the Semantic Condition as compared to the Evaluative Condition. Moreover, this effect generalized toward novel objects that were never presented during the exposure procedure. The explicit measure of evaluation mimicked this effect, although it failed to reach conventional levels of statistical significance. No effects were found in terms of automatic approach/avoidance tendencies. Potential implications for the treatment of anxiety disorders are discussed. PMID:27242626

How to Modify (Implicit) Evaluations of Fear-Related Stimuli: Effects of Feature-Specific Attention Allocation.

PubMed

Vanaelst, Jolien; Spruyt, Adriaan; De Houwer, Jan

2016-01-01

We demonstrate that feature-specific attention allocation influences the way in which repeated exposure modulates implicit and explicit evaluations toward fear-related stimuli. During an exposure procedure, participants were encouraged to assign selective attention either to the evaluative meaning (i.e., Evaluative Condition) or a non-evaluative, semantic feature (i.e., Semantic Condition) of fear-related stimuli. The influence of the exposure procedure was captured by means of a measure of implicit evaluation, explicit evaluative ratings, and a measure of automatic approach/avoidance tendencies. As predicted, the implicit measure of evaluation revealed a reduced expression of evaluations in the Semantic Condition as compared to the Evaluative Condition. Moreover, this effect generalized toward novel objects that were never presented during the exposure procedure. The explicit measure of evaluation mimicked this effect, although it failed to reach conventional levels of statistical significance. No effects were found in terms of automatic approach/avoidance tendencies. Potential implications for the treatment of anxiety disorders are discussed.

General anesthesia in cardiac surgery: a review of drugs and practices.

PubMed

Alwardt, Cory M; Redford, Daniel; Larson, Douglas F

2005-06-01

General anesthesia is defined as complete anesthesia affecting the entire body with loss of consciousness, analgesia, amnesia, and muscle relaxation. There is a wide spectrum of agents able to partially or completely induce general anesthesia. Presently, there is not a single universally accepted technique for anesthetic management during cardiac surgery. Instead, the drugs and combinations of drugs used are derived from the pathophysiologic state of the patient and individual preference and experience of the anesthesiologist. According to the definition of general anesthesia, current practices consist of four main components: hypnosis, analgesia, amnesia, and muscle relaxation. Although many of the agents highlighted in this review are capable of producing more than one of these effects, it is logical that drugs producing these effects are given in combination to achieve the most beneficial effect. This review features a discussion of currently used anesthetic drugs and clinical practices of general anesthesia during cardiac surgery. The information in this particular review is derived from textbooks, current literature, and personal experience, and is designed as a general overview of anesthesia during cardiac surgery.

The Compton generator revisited

NASA Astrophysics Data System (ADS)

Siboni, S.

2014-09-01

The Compton generator, introduced in 1913 by the US physicist A H Compton as a relatively simple device to detect the Earth's rotation with respect to the distant stars, is analyzed and discussed in a general perspective. The paper introduces a generalized definition of the generator, emphasizing the special features of the original apparatus, and provides a suggestive interpretation of the way the device works. To this end, an intriguing electromagnetic analogy is developed, which turns out to be particularly useful in simplifying the calculations. Besides the more extensive description of the Compton generator in itself, the combined use of concepts and methods coming from different fields of physics, such as particle dynamics in moving references frames, continuum mechanics and electromagnetism, may be of interest to both teachers and graduate students.

Two-potential approach for electron-molecular collisions at intermediate and high energies - Application to e-N2 scatterings

NASA Technical Reports Server (NTRS)

Choi, B. H.; Poe, R. T.; Sun, J. C.; Shan, Y.

1979-01-01

A general theoretical approach is proposed for the calculation of elastic, vibrational, and rotational transitions for electron-molecule scattering at intermediate and high-electron-impact energies. In this formulation, contributions to the scattering process come from the incoherent sum of two dominant potentials: a short-range shielded nuclear Coulomb potential from individual atomic centers, and a permanent/induced long-range potential. Application to e-N2 scattering from 50-500 eV incident electron energies has yielded good agreement with absolutely calibrated experiments. Comparisons with other theoretical approaches are made. The physical picture as well as the general features of electron-molecule scattering process are discussed within the framework of the two-potential approach.

Effect of X-ray Line Spectra Profile Fitting with Pearson VII, Pseudo-Voigt and Generalized Fermi Functions on Asphalt Binder Aromaticity and Crystallite Parameters

NASA Astrophysics Data System (ADS)

Gebresellasie, K.; Shirokoff, J.; Lewis, J. C.

2012-12-01

X-ray line spectra profile fitting using Pearson VII, pseudo-Voigt and generalized Fermi functions was performed on asphalt binders prior to the calculation of aromaticity and crystallite size parameters. The effects of these functions on the results are presented and discussed in terms of the peak profile fit parameters, the uncertainties in calculated values that can arise owing to peak shape, peak features in the pattern and crystallite size according to the asphalt models (Yen, modified Yen or Yen-Mullins) and theories. Interpretation of these results is important in terms of evaluating the performance of asphalt binders widely used in the application of transportation systems (roads, highways, airports).

12 CFR Appendix M1 to Part 226 - Generic Repayment Estimates

Code of Federal Regulations, 2010 CFR

2010-01-01

... general revolving feature that applies to balances existing before January 1, 2009; a minimum payment formula applicable to a general revolving feature that applies to balances incurred on or after January 1... general revolving feature that applies to balances incurred on or after January 1, 2009, and apply that...

Review of General Algorithmic Features for Genome Assemblers for Next Generation Sequencers

PubMed Central

Wajid, Bilal; Serpedin, Erchin

2012-01-01

In the realm of bioinformatics and computational biology, the most rudimentary data upon which all the analysis is built is the sequence data of genes, proteins and RNA. The sequence data of the entire genome is the solution to the genome assembly problem. The scope of this contribution is to provide an overview on the art of problem-solving applied within the domain of genome assembly in the next-generation sequencing (NGS) platforms. This article discusses the major genome assemblers that were proposed in the literature during the past decade by outlining their basic working principles. It is intended to act as a qualitative, not a quantitative, tutorial to all working on genome assemblers pertaining to the next generation of sequencers. We discuss the theoretical aspects of various genome assemblers, identifying their working schemes. We also discuss briefly the direction in which the area is headed towards along with discussing core issues on software simplicity. PMID:22768980

Cotinine analytical workshop report: consideration of analytical methods for determining cotinine in human body fluids as a measure of passive exposure to tobacco smoke.

PubMed Central

Watts, R R; Langone, J J; Knight, G J; Lewtas, J

1990-01-01

A two-day technical workshop was convened November 10-11, 1986, to discuss analytical approaches for determining trace amounts of cotinine in human body fluids resulting from passive exposure to environmental tobacco smoke (ETS). The workshop, jointly sponsored by the U.S. Environmental Protection Agency and Centers for Disease Control, was attended by scientists with expertise in cotinine analytical methodology and/or conduct of human monitoring studies related to ETS. The workshop format included technical presentations, separate panel discussions on chromatography and immunoassay analytical approaches, and group discussions related to the quality assurance/quality control aspects of future monitoring programs. This report presents a consensus of opinion on general issues before the workshop panel participants and also a detailed comparison of several analytical approaches being used by the various represented laboratories. The salient features of the chromatography and immunoassay analytical methods are discussed separately. PMID:2190812

A hierarchy for modeling high speed propulsion systems

NASA Technical Reports Server (NTRS)

Hartley, Tom T.; Deabreu, Alex

1991-01-01

General research efforts on reduced order propulsion models for control systems design are overviewed. Methods for modeling high speed propulsion systems are discussed including internal flow propulsion systems that do not contain rotating machinery, such as inlets, ramjets, and scramjets. The discussion is separated into four areas: (1) computational fluid dynamics models for the entire nonlinear system or high order nonlinear models; (2) high order linearized models derived from fundamental physics; (3) low order linear models obtained from the other high order models; and (4) low order nonlinear models (order here refers to the number of dynamic states). Included in the discussion are any special considerations based on the relevant control system designs. The methods discussed are for the quasi-one-dimensional Euler equations of gasdynamic flow. The essential nonlinear features represented are large amplitude nonlinear waves, including moving normal shocks, hammershocks, simple subsonic combustion via heat addition, temperature dependent gases, detonations, and thermal choking. The report also contains a comprehensive list of papers and theses generated by this grant.

What features do Dutch university students prefer in a smartphone application for promotion of physical activity? A qualitative approach.

PubMed

Middelweerd, Anouk; van der Laan, Danielle M; van Stralen, Maartje M; Mollee, Julia S; Stuij, Mirjam; te Velde, Saskia J; Brug, Johannes

2015-03-01

The transition from adolescence to early adulthood is a critical period in which there is a decline in physical activity (PA). College and university students make up a large segment of this age group. Smartphones may be used to promote and support PA. The purpose of this qualitative study was to explore Dutch students' preferences regarding a PA application (PA app) for smartphones. Thirty Dutch students (aged 18-25 years) used a PA app for three weeks and subsequently attended a focus group discussion (k = 5). To streamline the discussion, a discussion guide was developed covering seven main topics, including general app usage, usage and appreciation of the PA app, appreciation of and preferences for its features and the sharing of PA accomplishments through social media. The discussions were audio and video recorded, transcribed and analysed according to conventional content analysis. The participants, aged 21 ± 2 years, were primarily female (67%). Several themes emerged: app usage, technical aspects, PA assessment, coaching aspects and sharing through social media. Participants most often used social networking apps (e.g., Facebook or Twitter), communication apps (e.g., WhatsApp) and content apps (e.g., news reports or weather forecasts). They preferred a simple and structured layout without unnecessary features. Ideally, the PA app should enable users to tailor it to their personal preferences by including the ability to hide features. Participants preferred a companion website for detailed information about their accomplishments and progress, and they liked tracking their workout using GPS. They preferred PA apps that coached and motivated them and provided tailored feedback toward personally set goals. They appreciated PA apps that enabled competition with friends by ranking or earning rewards, but only if the reward system was transparent. They were not willing to share their regular PA accomplishments through social media unless they were exceptionally positive. Participants prefer PA apps that coach and motivate them, that provide tailored feedback toward personally set goals and that allow competition with friends.

How do gut feelings feature in tutorial dialogues on diagnostic reasoning in GP traineeship?

PubMed

Stolper, C F; Van de Wiel, M W J; Hendriks, R H M; Van Royen, P; Van Bokhoven, M A; Van der Weijden, T; Dinant, G J

2015-05-01

Diagnostic reasoning is considered to be based on the interaction between analytical and non-analytical cognitive processes. Gut feelings, a specific form of non-analytical reasoning, play a substantial role in diagnostic reasoning by general practitioners (GPs) and may activate analytical reasoning. In GP traineeships in the Netherlands, trainees mostly see patients alone but regularly consult with their supervisors to discuss patients and problems, receive feedback, and improve their competencies. In the present study, we examined the discussions of supervisors and their trainees about diagnostic reasoning in these so-called tutorial dialogues and how gut feelings feature in these discussions. 17 tutorial dialogues focussing on diagnostic reasoning were video-recorded and transcribed and the protocols were analysed using a detailed bottom-up and iterative content analysis and coding procedure. The dialogues were segmented into quotes. Each quote received a content code and a participant code. The number of words per code was used as a unit of analysis to quantitatively compare the contributions to the dialogues made by supervisors and trainees, and the attention given to different topics. The dialogues were usually analytical reflections on a trainee's diagnostic reasoning. A hypothetico-deductive strategy was often used, by listing differential diagnoses and discussing what information guided the reasoning process and might confirm or exclude provisional hypotheses. Gut feelings were discussed in seven dialogues. They were used as a tool in diagnostic reasoning, inducing analytical reflection, sometimes on the entire diagnostic reasoning process. The emphasis in these tutorial dialogues was on analytical components of diagnostic reasoning. Discussing gut feelings in tutorial dialogues seems to be a good educational method to familiarize trainees with non-analytical reasoning. Supervisors need specialised knowledge about these aspects of diagnostic reasoning and how to deal with them in medical education.

Chaco astronomies

NASA Astrophysics Data System (ADS)

Martín López, Alejandro

2015-08-01

This presentation discusses the result of 18 years of ethnographic and ethnohistorical studies on Chaco astronomies. The main features of the systems of astronomical knowledge of the Chaco Aboriginal groups will be discussed. In particular we will discuss the relevance of the Milky Way, the role of the visibility of the Pleiades, the ways in which the celestial space is represented, the constitution of astronomical orientations in geographic space, etc. We also address a key feature of their vision of the cosmos: the universe is seen by these groups as a socio-cosmos, where humans and non-humans are related. These are therefore actually socio-cosmologies. We will link this to the theories of Chaco Aboriginal groups about power and political relations.We will discuss how the study of Aboriginal astronomies must be performed along with the studies about astronomies of Creole people and European migrants, as well as anthropological studies about the science teaching in the formal education system and by the mass media. In this form we will discuss the relevance of a very complex system of interethnic relations for the conformation of these astronomical representations and practices.We will also discuss the general methodological implications of this case for the ethnoastronomy studies. In particular we will talk about the advantages of a study of regional scope and about the key importance of put in contact the ethnoastronomy with contemporary issues in social sciences.We also analyze the importance of ethnoastronomy studies in relation to studies of sociology of science, especially astronomy. We also study the potential impact on improving formal and informal science curricula and in shaping effective policies to protect the tangible and intangible astronomical heritage in a context of respect for the rights of Aboriginal groups.

The origin of the bifurcating style in Asteraceae (Compositae)

PubMed Central

Katinas, Liliana; Hernández, Marcelo P.; Arambarri, Ana M.; Funk, Vicki A.

2016-01-01

Background and Aims The plant family Asteraceae (Compositae) exhibits remarkable morphological variation in the styles of its members. Lack of studies on the styles of the sister families to Asteraceae, Goodeniaceae and Calyceraceae, obscures our understanding of the origin and evolution of this reproductive feature in these groups. The aim of this work was to perform a comparative study of style morphology and to discuss the relevance of important features in the evolution of Asteraceae and its sister families. Methods The histochemistry, venation and general morphology of the styles of members of Goodeniaceae, Calyceraceae and early branching lineages of Asteraceae were analysed and put in a phylogenetic framework to discuss the relevance of style features in the evolution of these families. Key Results The location of lipophilic substances allowed differentiation of receptive from non-receptive style papillae, and the style venation in Goodeniaceae and Calyceraceae proved to be distinctive. There were several stages of style evolution from Goodeniaceae to Asteraceae involving connation and elongation of veins, development of bilobation from an initially cup-shaped style, and a redistribution of the receptive and non-receptive papillae. Conclusions These developments resulted in bifurcation in the styles of Asteraceae, with each branch face having a different function, and it is suggested here as a mechanism that promoted outcrossing, which in turn led to the great diversification in the family. PMID:27098086

EO-1 analysis applicable to coastal characterization

NASA Astrophysics Data System (ADS)

Burke, Hsiao-hua K.; Misra, Bijoy; Hsu, Su May; Griffin, Michael K.; Upham, Carolyn; Farrar, Kris

2003-09-01

The EO-1 satellite is part of NASA's New Millennium Program (NMP). It consists of three imaging sensors: the multi-spectral Advanced Land Imager (ALI), Hyperion and Atmospheric Corrector. Hyperion provides a high-resolution hyperspectral imager capable of resolving 220 spectral bands (from 0.4 to 2.5 micron) with a 30 m resolution. The instrument images a 7.5 km by 100 km land area per image. Hyperion is currently the only space-borne HSI data source since the launch of EO-1 in late 2000. The discussion begins with the unique capability of hyperspectral sensing to coastal characterization: (1) most ocean feature algorithms are semi-empirical retrievals and HSI has all spectral bands to provide legacy with previous sensors and to explore new information, (2) coastal features are more complex than those of deep ocean that coupled effects are best resolved with HSI, and (3) with contiguous spectral coverage, atmospheric compensation can be done with more accuracy and confidence, especially since atmospheric aerosol effects are the most pronounced in the visible region where coastal feature lie. EO-1 data from Chesapeake Bay from 19 February 2002 are analyzed. In this presentation, it is first illustrated that hyperspectral data inherently provide more information for feature extraction than multispectral data despite Hyperion has lower SNR than ALI. Chlorophyll retrievals are also shown. The results compare favorably with data from other sources. The analysis illustrates the potential value of Hyperion (and HSI in general) data to coastal characterization. Future measurement requirements (air borne and space borne) are also discussed.

Investigating the Consistency of Models for Water Splitting Systems by Light and Voltage Modulated Techniques.

PubMed

Bertoluzzi, Luca; Bisquert, Juan

2017-01-05

The optimization of solar energy conversion devices relies on their accurate and nondestructive characterization. The small voltage perturbation techniques of impedance spectroscopy (IS) have proven to be very powerful to identify the main charge storage modes and charge transfer processes that control device operation. Here we establish the general connection between IS and light modulated techniques such as intensity modulated photocurrent (IMPS) and photovoltage spectroscopies (IMVS) for a general system that converts light to energy. We subsequently show how these techniques are related to the steady-state photocurrent and photovoltage and the external quantum efficiency. Finally, we express the IMPS and IMVS transfer functions in terms of the capacitive and resistive features of a general equivalent circuit of IS for the case of a photoanode used for solar fuel production. We critically discuss how much knowledge can be extracted from the combined use of those three techniques.

Do cybernetics, system science and fuzzy sets share some epistemological problems. I. An analysis of cybernetics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tamburrini, G.; Termini, S.

1982-01-01

The general thesis underlying the present paper is that there are very strong methodological relations among cybernetics, system science, artificial intelligence, fuzzy sets and many other related fields. Then, in order to understand better both the achievements and the weak points of all the previous disciplines, one should look for some common features for looking at them in this general frame. What will be done is to present a brief analysis of the primitive program of cybernetics, presenting it as a case study useful for developing the previous thesis. Among the discussed points are the problems of interdisciplinarity and ofmore » the unity of cybernetics. Some implications of this analysis for a new reading of general system theory and fuzzy sets are briefly outlined at the end of the paper. 3 references.« less

The importance of internal facial features in learning new faces.

PubMed

Longmore, Christopher A; Liu, Chang Hong; Young, Andrew W

2015-01-01

For familiar faces, the internal features (eyes, nose, and mouth) are known to be differentially salient for recognition compared to external features such as hairstyle. Two experiments are reported that investigate how this internal feature advantage accrues as a face becomes familiar. In Experiment 1, we tested the contribution of internal and external features to the ability to generalize from a single studied photograph to different views of the same face. A recognition advantage for the internal features over the external features was found after a change of viewpoint, whereas there was no internal feature advantage when the same image was used at study and test. In Experiment 2, we removed the most salient external feature (hairstyle) from studied photographs and looked at how this affected generalization to a novel viewpoint. Removing the hair from images of the face assisted generalization to novel viewpoints, and this was especially the case when photographs showing more than one viewpoint were studied. The results suggest that the internal features play an important role in the generalization between different images of an individual's face by enabling the viewer to detect the common identity-diagnostic elements across non-identical instances of the face.

The Nature and Evolution of Interstellar Ices: Studies of Methanol and Carbon Monoxide

NASA Astrophysics Data System (ADS)

Chiar, Jean Elizabeth

The evolution of icy grain mantles is governed by the environment in which they exist. Infrared spectroscopy provides the observational means for detecting absorption features of molecules in the dust. The 3.3-4.0 μm spectral region contains the fundamental C-H stretching vibrations of alcohols and aliphatic hydrocarbons and provides a powerful method of characterizing the organic component of interstellar ices. I discuss hydrocarbon and methanol absorption in several lines of sight in Taurus. My results are consistent with a location for the 3.47 μm absorber in the grain mantle material rather than the core. The 3.54 μm methanol (CH3OH) feature is not detected in any of the sources and the possibility that methanol production requires warm conditions is discussed. The CO profile is observed in lines of sight toward embedded and background objects. Modeling of the CO features is accomplished by fitting laboratory data to the astronomical spectra. This is done for sources in several dark clouds. In general, CO spectra of field stars are best-fitted with pure (or mostly pure) CO along with a minor contribution from the polar component. In contrast, some embedded stars show distinctly different CO profiles. Their spectra are broader than those of field stars and some are best-fitted with laboratory mixtures which imply the presence of CO2. In other cases, where the CO-containing mantles exist in the foreground dust far away from the embedded object, the CO is in pure form. Observations of the 4.27 μm CO2 feature confirm the presence of processed dust along these same lines of sight. Thus, it is likely that the CO and CO2 exist in separate grain populations along the line of sight. In the final chapter of this thesis, I discuss the relevance of this work to origin of life studies.

DisVis: Visualizing Discussion Threads in Online Health Communities.

PubMed

Nakikj, Drashko; Mamykina, Lena

2016-01-01

An increasing number of individuals turn to online health communities (OHC) for information, advice and support about their health condition or disease. As a result of users' active participation, these forums store overwhelming volumes of information, which can make access to this information challenging and frustrating. To help overcome this problem we designed a discussion visualization tool DisVis. DisVis includes features for overviewing, browsing and finding particular information in a discussion. In a between subjects study, we tested the impact of DisVis on individuals' ability to provide an overview of a discussion, find topics of interest and summarize opinions. The study showed that after using the tool, the accuracy of participants' answers increased by 68% (p-value = 0.023) while at the same time exhibiting trends for reducing the time to answer by 38% with no statistical significance (p-value = 0.082). Qualitative interviews showed general enthusiasm regarding tools for improving browsing and searching for information within discussion forums, suggested different usage scenarios, highlighted opportunities for improving the design of DisVis, and outlined new directions for visualizing user-generated content within OHCs.

Theory and interpretation in qualitative studies from general practice: Why and how?

PubMed

Malterud, Kirsti

2016-03-01

In this article, I want to promote theoretical awareness and commitment among qualitative researchers in general practice and suggest adequate and feasible theoretical approaches. I discuss different theoretical aspects of qualitative research and present the basic foundations of the interpretative paradigm. Associations between paradigms, philosophies, methodologies and methods are examined and different strategies for theoretical commitment presented. Finally, I discuss the impact of theory for interpretation and the development of general practice knowledge. A scientific theory is a consistent and soundly based set of assumptions about a specific aspect of the world, predicting or explaining a phenomenon. Qualitative research is situated in an interpretative paradigm where notions about particular human experiences in context are recognized from different subject positions. Basic theoretical features from the philosophy of science explain why and how this is different from positivism. Reflexivity, including theoretical awareness and consistency, demonstrates interpretative assumptions, accounting for situated knowledge. Different types of theoretical commitment in qualitative analysis are presented, emphasizing substantive theories to sharpen the interpretative focus. Such approaches are clearly within reach for a general practice researcher contributing to clinical practice by doing more than summarizing what the participants talked about, without trying to become a philosopher. Qualitative studies from general practice deserve stronger theoretical awareness and commitment than what is currently established. Persistent attention to and respect for the distinctive domain of knowledge and practice where the research deliveries are targeted is necessary to choose adequate theoretical endeavours. © 2015 the Nordic Societies of Public Health.

Exact transition probabilities in a 6-state Landau–Zener system with path interference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sinitsyn, Nikolai A.

2015-04-23

In this paper, we identify a nontrivial multistate Landau–Zener (LZ) model for which transition probabilities between any pair of diabatic states can be determined analytically and exactly. In the semiclassical picture, this model features the possibility of interference of different trajectories that connect the same initial and final states. Hence, transition probabilities are generally not described by the incoherent successive application of the LZ formula. Finally, we discuss reasons for integrability of this system and provide numerical tests of the suggested expression for the transition probability matrix.

An enhanced obstacle avoiding system for AUV`s

DOE Office of Scientific and Technical Information (OSTI.GOV)

Conte, G.; Zanoli, S.M.

1994-12-31

This paper concerns the development of a sonar-based navigation and guidance system for underwater, unmanned vehicles. In particular, the authors describe and discuss an obstacle avoidance procedure that is capable of dealing with situations involving several obstacles. The main features of the system are the use of a Kalman filter, both for estimating data and for predicting the evolution of the observed scene, and the possibility of working at different levels of data abstraction. The system has shown satisfactory performances in dealing with moving obstacles in general situations.

ERBB oncogene proteins as targets for monoclonal antibodies.

PubMed

Polanovski, O L; Lebedenko, E N; Deyev, S M

2012-03-01

General properties of the family of tyrosine kinase ERBB receptors are considered in connection with their role in the generation of cascades of signal transduction in normal and tumor cells. Causes of acquisition of oncogene features by genes encoding these receptors and their role in tumorigenesis are analyzed. Anti-ERBB monoclonal antibodies approved for therapy are described in detail, and mechanisms of their antitumor activity and development of resistance to them are reviewed. The existing and the most promising strategies for creating and using monoclonal antibodies and their derivatives for therapy of cancer are discussed.

Handling of computational in vitro/in vivo correlation problems by Microsoft Excel: V. Predictive absorbability models.

PubMed

Langenbucher, Frieder

2007-08-01

This paper discusses Excel applications related to the prediction of drug absorbability from physicochemical constants. PHDISSOC provides a generalized model for pH profiles of electrolytic dissociation, water solubility, and partition coefficient. SKMODEL predicts drug absorbability, based on a log-log plot of water solubility and O/W partitioning; augmented by additional features such as electrolytic dissociation, melting point, and the dose administered. GIABS presents a mechanistic model of g.i. drug absorption. BIODATCO presents a database compiling relevant drug data to be used for quantitative predictions.

General features of the dissociative recombination of polyatomic molecules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pratt, S. T.; Jungen, Ch.; Schneider, I. F.

We discuss some aspects of a simple expression for the low-energy dissociative recombination cross section that applies when the recombination process is dominated by the indirect mechanism. In most previous applications, this expression has been applied to capture into vibrationally excited Rydberg states with the assumption that capture is always followed by prompt dissociation. Here we consider the dissociative recombination of larger polyatomic ions and electrons. More specifically, we consider capture into electronically core-excited Rydberg states, and begin to assess its potential importance for larger systems.

General features of the dissociative recombination of polyatomic molecules

DOE PAGES

Pratt, S. T.; Jungen, Ch.; Schneider, I. F.; ...

2015-01-29

We discuss some aspects of a simple expression for the low-energy dissociative recombination cross section that applies when the recombination process is dominated by the indirect mechanism. In most previous applications, this expression has been applied to capture into vibrationally excited Rydberg states with the assumption that capture is always followed by prompt dissociation. Here we consider the dissociative recombination of larger polyatomic ions and electrons. More specifically, we consider capture into electronically core-excited Rydberg states, and begin to assess its potential importance for larger systems.

Reducing the spectral index in supernatural inflation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, C.-M.; Cheung, Kingman; Division of Quantum Phases and Devices, School of Physics, Konkuk University, Seoul 143-701

2009-04-15

Supernatural inflation is an attractive model based on just a flat direction with soft supersymmetry breaking mass terms in the framework of supersymmetry. The beauty of the model is that it needs no fine-tuning. However, the prediction of the spectral index is n{sub s} > or approx. 1, in contrast to experimental data. In this paper, we discuss supernatural inflation with the spectral index reduced to n{sub s}=0.96 without any fine-tuning, considering the general feature that a flat direction is lifted by a nonrenormalizable term with an A-term.

Gaia archive

NASA Astrophysics Data System (ADS)

Hypki, Arkadiusz; Brown, Anthony

2016-06-01

The Gaia archive is being designed and implemented by the DPAC Consortium. The purpose of the archive is to maximize the scientific exploitation of the Gaia data by the astronomical community. Thus, it is crucial to gather and discuss with the community the features of the Gaia archive as much as possible. It is especially important from the point of view of the GENIUS project to gather the feedback and potential use cases for the archive. This paper presents very briefly the general ideas behind the Gaia archive and presents which tools are already provided to the community.

The built-in environment: the role of personality and physical activity.

PubMed

Rhodes, Ryan E

2006-04-01

Personality trait psychology has seen a reemergence in recent years, and researchers are beginning to apply personality models to understand health behavior habits. This review features recent research on personality correlates of physical activity (PA) and the integration of personality with PA-related social cognition. The current definition and status of general personality work is introduced followed by a review and discussion of the evidence for personality and PA relations. The review concludes with recommendations for personality-matched PA marketing and experimental and longitudinal designs.

Recent advances in redox flow cell storage systems

NASA Technical Reports Server (NTRS)

Thaller, L. H.

1979-01-01

Several features which were conceived and incorporated into complete redox systems that greatly enhanced its ability to be kept in proper charge balance, to be capable of internal voltage regulation, and in general be treated as a true multicell electrochemical system rather than an assembly of single cells that were wired together, were discussed. The technology status as it relates to the two application areas of solar photovoltaic/wind and distributed energy storage for electric utility applications was addressed. The cost and life advantages of redox systems were also covered.

Smart sensor for terminal homing

NASA Astrophysics Data System (ADS)

Panda, D.; Aggarwal, R.; Hummel, R.

1980-01-01

The practical scene matching problem is considered to present certain complications which must extend classical image processing capabilities. Certain aspects of the scene matching problem which must be addressed by a smart sensor for terminal homing are discussed. First a philosophy for treating the matching problem for the terminal homing scenario is outlined. Then certain aspects of the feature extraction process and symbolic pattern matching are considered. It is thought that in the future general ideas from artificial intelligence will be more useful for terminal homing requirements of fast scene recognition and pattern matching.

Real-time data archiving for GTA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, R.A.; Atkins, W.H.

1992-09-01

The architecture of the GTA control system, the nature of a typical GTA commissioning activity, and the varied interests of those analyzing the data make it challenging to develop a general-purpose scheme for archiving data and making the data available to those who will use it. Addressing the needs of those who develop and trouble-shoot hardware and software increases the challenge. This paper describes the aspects of GTA that affect archiving operations and discusses how the features of the EPICS archiving module meet a variety of needs for storing and accessing data.

Real-time data archiving for GTA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, R.A.; Atkins, W.H.

1992-01-01

The architecture of the GTA control system, the nature of a typical GTA commissioning activity, and the varied interests of those analyzing the data make it challenging to develop a general-purpose scheme for archiving data and making the data available to those who will use it. Addressing the needs of those who develop and trouble-shoot hardware and software increases the challenge. This paper describes the aspects of GTA that affect archiving operations and discusses how the features of the EPICS archiving module meet a variety of needs for storing and accessing data.

Noninvasive Study of Explosive Materials by Time Domain Spectroscopy and FTIR

NASA Astrophysics Data System (ADS)

Huang, Feng; Federici, John; Gary, Dale; Barat, Robert; Zimdars, David

2005-04-01

Transmission and reflection spectroscopy in the Terahertz (THz) range (˜ 3 to 0.1 mm) is potentially useful for the detection of explosives and biological agents. This paper describes the use of THz time domain spectroscopy (TDS) applied in transmission to the 1,3,5 trinitro-s-triazine (RDX), C4, Amonium Nitrate, etc. Samples were also subjected to Fourier Transform Infrared (FTIR) spectroscopy over the same range for comparison. General agreement confirms the absorption features found. The nature of THz technology applied in the noninvasive detection of such material is discussed.

Categorization in concentration camps as a collective fate: a comparison of homosexuals, Jehovah's Witnesses and political prisoners.

PubMed

Lautmann, R

1990-01-01

Using socio-historical data some critical features of Nazi Concentration Camps are discussed: uniqueness vs. normality; extermination vs. re-education of gay prisoners. The special fate of the Pink Triangle in comparison to other non-Jewish victims is demonstrated. The determinative qualities of life and death conditions in the camps are: the National Socialist interpretation of the prisoner category; the repressive content of social control; the marginalisation in general society. The relative strength of a single influence cannot be separated one from the other.

Latent autoimmune diabetes of the adult: current knowledge and uncertainty

PubMed Central

Laugesen, E; Østergaard, J A; Leslie, R D G

2015-01-01

Patients with adult-onset autoimmune diabetes have less Human Leucocyte Antigen (HLA)-associated genetic risk and fewer diabetes-associated autoantibodies compared with patients with childhood-onset Type 1 diabetes. Metabolic changes at diagnosis reflect a broad clinical phenotype ranging from diabetic ketoacidosis to mild non-insulin-requiring diabetes, also known as latent autoimmune diabetes of the adult (LADA). This latter phenotype is the most prevalent form of adult-onset autoimmune diabetes and probably the most prevalent form of autoimmune diabetes in general. Although LADA is associated with the same genetic and immunological features as childhood-onset Type 1 diabetes, it also shares some genetic features with Type 2 diabetes, which raises the question of genetic heterogeneity predisposing to this form of the disease. The potential value of screening patients with adult-onset diabetes for diabetes-associated autoantibodies to identify those with LADA is emphasized by their lack of clinically distinct features, their different natural history compared with Type 2 diabetes and their potential need for a dedicated management strategy. The fact that, in some studies, patients with LADA show worse glucose control than patients with Type 2 diabetes, highlights the need for further therapeutic studies. Challenges regarding classification, epidemiology, genetics, metabolism, immunology, clinical presentation and treatment of LADA were discussed at a 2014 workshop arranged by the Danish Diabetes Academy. The presentations and discussions are summarized in this review, which sets out the current ideas and controversies surrounding this form of diabetes. What’s new? Latent autoimmune diabetes of the adult (LADA) is an autoimmune diabetes defined by adult-onset, presence of diabetes associated autoantibodies, and no insulin treatment requirement for a period after diagnosis. Immunologically, glutamic acid decarboxylase 65 autoantibodies are by far the most common autoantibody in adult-onset diabetes. LADA is the most prevalent form of adult-onset autoimmune diabetes and probably the most prevalent form of autoimmune diabetes in general. LADA shares genetic features with both type 1 and type 2 diabetes. Phenotypically, LADA patients are often misdiagnosed as having type 2 diabetes. LADA patients generally have worse HbA1c levels than type 2 diabetes patients. Clinically, LADA patients tend to have a lower mean age at diabetes onset, lower body mass index and more frequent need for insulin treatment than patients with type 2 diabetes. Management of LADA may require a dedicated strategy, yet currently there is a paucity of randomized controlled trial data. PMID:25601320

An Integrated Account of Generalization across Objects and Features

ERIC Educational Resources Information Center

Kemp, Charles; Shafto, Patrick; Tenenbaum, Joshua B.

2012-01-01

Humans routinely make inductive generalizations about unobserved features of objects. Previous accounts of inductive reasoning often focus on inferences about a single object or feature: accounts of causal reasoning often focus on a single object with one or more unobserved features, and accounts of property induction often focus on a single…

Dental management of patient with Williams Syndrome - A case report.

PubMed

Wong, Daniel; Ramachandra, Srinivas Sulugodu; Singh, Ashish Kumar

2015-01-01

Williams syndrome is a multisystemic rare genetic disorder caused by deletion of 26-28 genes in the long arm of chromosome 7. It is characterized by developmental and physical abnormalities including congenital cardiovascular abnormalities, mental retardation, neurological features, growth deficiency, genitourinary manifestations, gastrointestinal problems, musculoskeletal problems, unique behavioral characteristics, and dental problems. Dental abnormalities include malocclusion, hypodontia, malformed teeth, taurodontism, pulp stones, increased space between teeth, enamel hypoplasia, and high prevalence of dental caries. Authors report a 17-year-old female patient with underlying Williams syndrome. Oral features and problems seen in the patient are listed. Malocclusion and screwdriver shaped teeth were noticed. Generalized widening of the periodontal ligament space with vital teeth was seen. This finding has not been reported in cases of Williams syndrome earlier. Precautions taken during dental treatment in patients with Williams syndrome are also discussed.

Human factors in cockpit automation: A field study of flight crew transition

NASA Technical Reports Server (NTRS)

Wiener, E. L.

1985-01-01

The factors which affected two groups of airline pilots in the transition from traditional airline cockpits to a highly automated version were studied. All pilots were highly experienced in traditional models of the McDonnell-Douglas DC-9 prior to their transition to the more automated DC-9-80. Specific features of the new aircraft, particularly the digital flight guidance system (DFGS) and other automatic features such as the autothrottle system (ATS), autobrake, and digital display were studied. Particular attention was paid to the first 200 hours of line flying experience in the new aircraft, and the difficulties that some pilots found in adapting to the new systems during this initial operating period. Efforts to prevent skill loss from automation, training methods, traditional human factors issues, and general views of the pilots toward cockpit automation are discussed.

Early Cambrian sipunculan worms from southwest China.

PubMed Central

Huang, Di-Ying; Chen, Jun-Yuan; Vannier, Jean; Saiz Salinas, J. I.

2004-01-01

We report the discovery of sipunculan worms from the Lower Cambrian Maotianshan Shale, near Kunming (southwest China). Their sipunculan identity is evidenced by the general morphology of the animals (sausage-shaped body with a slender retractable introvert and a wider trunk) and by other features, both external (e.g. perioral crown of tentacles, and hooks, papillae and wrinkle rings on the body surface) and internal (U-shaped gut, and the anus opening near the introvert-trunk junction). The three fossil forms (Archaeogolfingia caudata gen. et sp. nov., Cambrosipunculus tentaculatus gen. et sp. nov. and Cambrosipunculus sp.) have striking similarities to modern sipunculans, especially the Golfingiidae to which their evolutionary relationships are discussed. This study suggests that most typical features of extant sipunculans have undergone only limited changes since the Early Cambrian, thus indicating a possible evolutionary stasis over the past 520 Myr. PMID:15306286

Early Cambrian sipunculan worms from southwest China.

PubMed

Huang, Di-Ying; Chen, Jun-Yuan; Vannier, Jean; Saiz Salinas, J I

2004-08-22

We report the discovery of sipunculan worms from the Lower Cambrian Maotianshan Shale, near Kunming (southwest China). Their sipunculan identity is evidenced by the general morphology of the animals (sausage-shaped body with a slender retractable introvert and a wider trunk) and by other features, both external (e.g. perioral crown of tentacles, and hooks, papillae and wrinkle rings on the body surface) and internal (U-shaped gut, and the anus opening near the introvert-trunk junction). The three fossil forms (Archaeogolfingia caudata gen. et sp. nov., Cambrosipunculus tentaculatus gen. et sp. nov. and Cambrosipunculus sp.) have striking similarities to modern sipunculans, especially the Golfingiidae to which their evolutionary relationships are discussed. This study suggests that most typical features of extant sipunculans have undergone only limited changes since the Early Cambrian, thus indicating a possible evolutionary stasis over the past 520 Myr.

Implementing standard setting into the Conjoint MAFP/FRACGP Part 1 examination - Process and issues.

PubMed

Chan, S C; Mohd Amin, S; Lee, T W

2016-01-01

The College of General Practitioners of Malaysia and the Royal Australian College of General Practitioners held the first Conjoint Member of the College of General Practitioners (MCGP)/Fellow of Royal Australian College of General Practitioners (FRACGP) examination in 1982, later renamed the Conjoint MAFP/FRACGP examinations. The examination assesses competency for safe independent general practice and as family medicine specialists in Malaysia. Therefore, a defensible standard set pass mark is imperative to separate the competent from the incompetent. This paper discusses the process and issues encountered in implementing standard setting to the Conjoint Part 1 examination. Critical to success in standard setting were judges' understanding of the process of the modified Angoff method, defining the borderline candidate's characteristics and the composition of judges. These were overcome by repeated hands-on training, provision of detailed guidelines and careful selection of judges. In December 2013, 16 judges successfully standard set the Part 1 Conjoint examinations, with high inter-rater reliability: Cronbach's alpha coefficient 0.926 (Applied Knowledge Test), 0.921 (Key Feature Problems).

How Justice Can Affect Jury Training Abstract Words Promotes Generalization to Concrete Words in Patients with Aphasia

PubMed Central

Sandberg, Chaleece; Kiran, Swathi

2014-01-01

Developing language treatments that not only improve trained items but also promote generalization to untrained items is a major focus in aphasia research. This study is a replication and extension of previous work that found that training abstract words in a particular context-category promotes generalization to concrete words but not vice versa (Kiran, Sandberg, & Abbott, 2009). Twelve persons with aphasia (5 female) with varying types and degrees of severity participated in a generative naming treatment based on the complexity account of treatment efficacy (CATE; Thompson, Shapiro, Kiran, & Sobecks, 2003). All participants were trained to generate abstract words in a particular context-category by analyzing the semantic features of the target words. Two other context-categories were used as controls. Ten of the twelve participants improved on the trained abstract words in the trained context-category. Eight of the ten participants who responded to treatment also generalized to concrete words in the same context-category. These results suggest that this treatment is both efficacious and efficient. We discuss possible mechanisms of training and generalization effects. PMID:24805853

Expanding the Possibilities of Discussion: A Strategic Approach to Using Online Discussion Boards in the Middle and High School English Classroom

ERIC Educational Resources Information Center

Ruday, Sean

2011-01-01

This paper focused on whether the use of online discussion boards can enhance the quality of interaction in the middle and high school English classroom, covering both the characteristics of online discussion boards and potential negative effects of their features. The features of online discussion boards, their effects, and how these boards…

Exploring How Different Features of Animations of Sodium Chloride Dissolution Affect Students' Explanations

NASA Astrophysics Data System (ADS)

Kelly, Resa M.; Jones, Loretta L.

2007-10-01

Animations of molecular structure and dynamics are often used to help students understand the abstract ideas of chemistry. This qualitative study investigated how the features of two different styles of molecular-level animation affected students' explanations of how sodium chloride dissolves in water. In small group sessions 18 college-level general chemistry students dissolved table salt in water, after which they individually viewed two animations of salt dissolution. Before and after viewing each animation the participants provided pictorial, written, and oral explanations of the process at the macroscopic and molecular levels. The students then discussed the animations as a group. An analysis of the data showed that students incorporated some of the microscopic structural and functional features from the animations into their explanations. However, oral explanations revealed that in many cases, participants who drew or wrote correct explanations did not comprehend their meanings. Students' drawings may have reflected only what they had seen, rather than a cohesive understanding. Students' explanations given after viewing the animations improved, but some prior misconceptions were retained and in some cases, new misconceptions appeared. Students reported that they found the animations useful in learning; however, they sometimes missed essential features when they watched the animation alone.

Extensions of algebraic image operators: An approach to model-based vision

NASA Technical Reports Server (NTRS)

Lerner, Bao-Ting; Morelli, Michael V.

1990-01-01

Researchers extend their previous research on a highly structured and compact algebraic representation of grey-level images which can be viewed as fuzzy sets. Addition and multiplication are defined for the set of all grey-level images, which can then be described as polynomials of two variables. Utilizing this new algebraic structure, researchers devised an innovative, efficient edge detection scheme. An accurate method for deriving gradient component information from this edge detector is presented. Based upon this new edge detection system researchers developed a robust method for linear feature extraction by combining the techniques of a Hough transform and a line follower. The major advantage of this feature extractor is its general, object-independent nature. Target attributes, such as line segment lengths, intersections, angles of intersection, and endpoints are derived by the feature extraction algorithm and employed during model matching. The algebraic operators are global operations which are easily reconfigured to operate on any size or shape region. This provides a natural platform from which to pursue dynamic scene analysis. A method for optimizing the linear feature extractor which capitalizes on the spatially reconfiguration nature of the edge detector/gradient component operator is discussed.

A critical appraisal of assimilationist and radical ideologies underlying same-sex marriage in LGBT communities in the United States.

PubMed

Yep, Gust A; Lovaas, Karen E; Elia, John P

2003-01-01

Debates over same-sex marriage have reached the main stage of contemporary U.S. politics. The purpose of this essay is to identify and examine how sexual ideologies in U.S. LGBT communities inform and influence relationship construction in general and same-sex marriage in particular. To accomplish this, we first discuss the nature of sexual ideologies. Next, we identify current sexual ideologies in LGBT communities and examine some of their fundamental features and their implications for relationship construction with a focus on same-sex marriage. We conclude with a discussion of what is potentially gained and lost by same-sex matrimonial bonds and explore some of the prospects of relationship construction within LGBT communities in the future.

S -matrix calculations of energy levels of sodiumlike ions

DOE PAGES

Sapirstein, J.; Cheng, K. T.

2015-06-24

A recent S -matrix-based QED calculation of energy levels of the lithium isoelectronic sequence is extended to the general case of a valence electron outside an arbitrary filled core. Emphasis is placed on modifications of the lithiumlike formulas required because more than one core state is present, and an unusual feature of the two-photon exchange contribution involving autoionizing states is discussed. Here, the method is illustrated with a calculation of the energy levels of sodiumlike ions, with results for 3s 1/2, 3p 1/2, and 3p 3/2 energies tabulated for the range Z = 30 – 100 . Comparison with experimentmore » and other calculations is given, and prospects for extension of the method to ions with more complex electronic structure discussed.« less

Pollution of ground water in Europe

PubMed Central

Buchan, S.; Key, A.

1956-01-01

This paper discusses pollution of ground water in 20 countries of the European region, giving for each an account of the geology and hydrogeology, water supplies, the extent and nature of ground water pollution, and the legal, administrative, and technical means of controlling that pollution. For the countries not considered in the preceding article on surface water pollution, an account is also given of the superficial physical features, rainfall, population, and industries. A general discussion follows of such questions as the ways in which ground water pollution may occur, the factors mitigating or aggravating pollution, and ways of protection against pollution. The authors consider that the problem of ground water pollution in Europe may well be more serious than it would appear to be on the evidence so far obtained. PMID:13374533

General Astrophysics Science Enabled by the HabEx Ultraviolet Spectrograph (UVS)

NASA Astrophysics Data System (ADS)

Scowen, Paul; Clarke, John; Gaudi, B. Scott; Kiessling, Alina; Martin, Stefan; Somerville, Rachel; Stern, Daniel; HabEx Science and Technology Definition Team

2018-01-01

The Habitable Exoplanet Imaging Mission (HabEx) is one of the four large mission concepts being studied by NASA as input to the upcoming 2020 Decadal Survey. The mission implements two world-class General Astrophysics instruments as part of its complement of instrumentation to enable compelling science using the 4m aperture. The Ultraviolet Spectrograph has been designed to address cutting edge far ultraviolet (FUV) science that has not been possible with the Hubble Space Telescope, and to open up a wide range of capabilities that will advance astrophysics as we look into the 2030s. Our poster discusses some of those science drivers and possible applications, which range from Solar System science, to nearby and more distant studies of star formation, to studies of the circumgalactic and intergalactic mediums where the ecology of mass and energy transfer are vital to understanding stellar and galactic evolution. We discuss the performance features of the instrument that include a large 3’x3’ field of view for multi-object spectroscopy, and some 20 grating modes for a variety of spectral resolution and coverage.

Questionnaire about psychology/disease correlation–I

PubMed Central

Ojog, DG; Pănescu, OM; Rusu, EC; Tănăsescu, MD

2011-01-01

Rationale: The existing personality inventories are exploring too general psychological features so that the possible psychology/disease associations might be leveled out. Objective: We attempt to build a tool to explore the possible correlation between certain psychological features and the most common internal disorders. Method: We have used two questionnaires containing many pairs of synonymous items (necessary for assessing the consistency of the answers). The items are divided into four main domains: preoccupation for the basal conditions of existence (health/ disease/ death, fear, money, lodging); interaction with other people; action, will/ volition, self-assertion; and preoccupation with the exterior. In this first article we are presenting the correlations between items of the first domain, based on the answers from our first 3138 respondents. Results and discussion: The concern about health is best reflected by general formulations. The desire for security is best expressed by items combining the worry about money and dwelling, and worst by items reflecting the eagerness to gain, keep or judiciously spend money. Among the various fears, those of future, darkness, and loneliness are better indicators of security concern. In assessing the anxiety about safety/ security, specific worries are more revelatory than the general ones. Precaution and inclination for order are the best indicators for the aspiration to stability. Poorer ones are the desire for cleanliness and the tendency to attachment. Health and security concerns seem to be consistently linked. The consistency evaluating system will be based upon pairs of synonymous items correlated with a10–200 or less error probability Abbreviations: PP = psychological profile; PF = personality feature; Q1/ Q2/ Q3 = first/ second/ third questionnaire; HeSD = health subdomain; SeSD = security subdomain; StSD = stability subdomain; ChiSq = chi square; ErrProb = error probability (probability of error). PMID:21505574

Deep and Structured Robust Information Theoretic Learning for Image Analysis.

PubMed

Deng, Yue; Bao, Feng; Deng, Xuesong; Wang, Ruiping; Kong, Youyong; Dai, Qionghai

2016-07-07

This paper presents a robust information theoretic (RIT) model to reduce the uncertainties, i.e. missing and noisy labels, in general discriminative data representation tasks. The fundamental pursuit of our model is to simultaneously learn a transformation function and a discriminative classifier that maximize the mutual information of data and their labels in the latent space. In this general paradigm, we respectively discuss three types of the RIT implementations with linear subspace embedding, deep transformation and structured sparse learning. In practice, the RIT and deep RIT are exploited to solve the image categorization task whose performances will be verified on various benchmark datasets. The structured sparse RIT is further applied to a medical image analysis task for brain MRI segmentation that allows group-level feature selections on the brain tissues.

Information on black-footed ferret biology collected within the framework of ferret conservation

USGS Publications Warehouse

Biggins, Dean E.

2012-01-01

Once feared to be extinct, black-footed ferrets (Mustela nigripes) were rediscovered near Meeteetse, Wyoming, in 1981, resulting in renewed conservation and research efforts for this highly endangered species. A need for information directly useful to recovery has motivated much monitoring of ferrets since that time, but field activities have enabled collection of data relevant to broader biological themes. This special feature is placed in a context of similar books and proceedings devoted to ferret biology and conservation. Articles include general observations on ferrets, modeling of potential impacts of ferrets on prairie dogs (Cynomys spp.), discussions on relationships of ferrets to prairie dog habitats at several spatial scales (from individual burrows to patches of burrow systems) and a general treatise on the status of black-footed ferret recovery.

Two generalizations of Kohonen clustering

NASA Technical Reports Server (NTRS)

Bezdek, James C.; Pal, Nikhil R.; Tsao, Eric C. K.

1993-01-01

The relationship between the sequential hard c-means (SHCM), learning vector quantization (LVQ), and fuzzy c-means (FCM) clustering algorithms is discussed. LVQ and SHCM suffer from several major problems. For example, they depend heavily on initialization. If the initial values of the cluster centers are outside the convex hull of the input data, such algorithms, even if they terminate, may not produce meaningful results in terms of prototypes for cluster representation. This is due in part to the fact that they update only the winning prototype for every input vector. The impact and interaction of these two families with Kohonen's self-organizing feature mapping (SOFM), which is not a clustering method, but which often leads ideas to clustering algorithms is discussed. Then two generalizations of LVQ that are explicitly designed as clustering algorithms are presented; these algorithms are referred to as generalized LVQ = GLVQ; and fuzzy LVQ = FLVQ. Learning rules are derived to optimize an objective function whose goal is to produce 'good clusters'. GLVQ/FLVQ (may) update every node in the clustering net for each input vector. Neither GLVQ nor FLVQ depends upon a choice for the update neighborhood or learning rate distribution - these are taken care of automatically. Segmentation of a gray tone image is used as a typical application of these algorithms to illustrate the performance of GLVQ/FLVQ.

The effect of feature selection methods on computer-aided detection of masses in mammograms

NASA Astrophysics Data System (ADS)

Hupse, Rianne; Karssemeijer, Nico

2010-05-01

In computer-aided diagnosis (CAD) research, feature selection methods are often used to improve generalization performance of classifiers and shorten computation times. In an application that detects malignant masses in mammograms, we investigated the effect of using a selection criterion that is similar to the final performance measure we are optimizing, namely the mean sensitivity of the system in a predefined range of the free-response receiver operating characteristics (FROC). To obtain the generalization performance of the selected feature subsets, a cross validation procedure was performed on a dataset containing 351 abnormal and 7879 normal regions, each region providing a set of 71 mass features. The same number of noise features, not containing any information, were added to investigate the ability of the feature selection algorithms to distinguish between useful and non-useful features. It was found that significantly higher performances were obtained using feature sets selected by the general test statistic Wilks' lambda than using feature sets selected by the more specific FROC measure. Feature selection leads to better performance when compared to a system in which all features were used.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Xiongyi; Groves, John T.

Since our initial report in 1976, the oxygen rebound mechanism has become the consensus mechanistic feature for an expanding variety of enzymatic C–H functionalization reactions and small molecule biomimetic catalysts. For both the biotransformations and models, an initial hydrogen atom abstraction from the substrate (R–H) by high-valent iron-oxo species (Fe n=O) generates a substrate radical and a reduced iron hydroxide, [Fe n-1–OH ·R]. This caged radical pair then evolves on a complicated energy landscape through a number of reaction pathways, such as oxygen rebound to form R–OH, rebound to a non-oxygen atom affording R–X, electron transfer of the incipient radicalmore » to yield a carbocation, R +, desaturation to form olefins, and radical cage escape. These various flavors of the rebound process, often in competition with each other, give rise to the wide range of C–H functionalization reactions performed by iron-containing oxygenases. In this review, we first recount the history of radical rebound mechanisms, their general features, and key intermediates involved. We will discuss in detail the factors that affect the behavior of the initial caged radical pair and the lifetimes of the incipient substrate radicals. Several representative examples of enzymatic C–H transformations are selected to illustrate how the behaviors of the radical pair [Fe n-1–OH ·R] determine the eventual reaction outcome. Finally, we discuss the powerful potential of “radical rebound” processes as a general paradigm for developing novel C–H functionalization reactions with synthetic, biomimetic catalysts. We envision that new chemistry will continue to arise by bridging enzymatic “radical rebound” with synthetic organic chemistry.« less

DUST AROUND R CORONAE BOREALIS STARS. II. INFRARED EMISSION FEATURES IN AN H-POOR ENVIRONMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garcia-Hernandez, D. A.; Rao, N. Kameswara; Lambert, D. L., E-mail: agarcia@iac.es, E-mail: nkrao@iiap.res.in, E-mail: dll@astro.as.utexas.edu

2013-08-20

Residual Spitzer/Infrared Spectrograph spectra for a sample of 31 R Coronae Borealis (RCB) stars are presented and discussed in terms of narrow emission features superimposed on the quasi-blackbody continuous infrared emission. A broad {approx}6-10 {mu}m dust emission complex is seen in the RCBs showing an extreme H-deficiency. A secondary and much weaker {approx}11.5-15 {mu}m broad emission feature is detected in a few RCBs with the strongest {approx}6-10 {mu}m dust complex. The Spitzer infrared spectra reveal for the first time the structure within the {approx}6-10 {mu}m dust complex, showing the presence of strong C-C stretching modes at {approx}6.3 and 8.1 {mu}mmore » as well as of other dust features at {approx}5.9, 6.9, and 7.3 {mu}m, which are attributable to amorphous carbonaceous solids with little or no hydrogen. The few RCBs with only moderate H-deficiencies display the classical ''unidentified infrared bands (UIRs)'' and mid-infrared features from fullerene-related molecules. In general, the characteristics of the RCB infrared emission features are not correlated with the stellar and circumstellar properties, suggesting that the RCB dust features may not be dependent on the present physical conditions around RCB stars. The only exception seems to be the central wavelength of the 6.3 {mu}m feature, which is blueshifted in those RCBs showing also the UIRs, i.e., the RCBs with the smallest H deficiency.« less

The Analytic Structure of Scattering Amplitudes in N = 4 Super-Yang-Mills Theory

NASA Astrophysics Data System (ADS)

Litsey, Sean Christopher

We begin the dissertation in Chapter 1 with a discussion of tree-level amplitudes in Yang-. Mills theories. The DDM and BCJ decompositions of the amplitudes are described and. related to one another by the introduction of a transformation matrix. This is related to the. Kleiss-Kuijf and BCJ amplitude identities, and we conjecture a connection to the existence. of a BCJ representation via a condition on the generalized inverse of that matrix. Under. two widely-believed assumptions, this relationship is proved. Switching gears somewhat, we introduce the RSVW formulation of the amplitude, and the extension of BCJ-like features to residues of the RSVW integrand is proposed. Using the previously proven connection of BCJ representations to the generalized inverse condition, this extension is validated, including a version of gravitational double copy. The remainder of the dissertation involves an analysis of the analytic properties of loop. amplitudes in N = 4 super-Yang-Mills theory. Chapter 2 contains a review of the planar case, including an exposition of dual variables and momentum twistors, dual conformal symmetry, and their implications for the amplitude. After defining the integrand and on-shell diagrams, we explain the crucial properties that the amplitude has no poles at infinite momentum and that its leading singularities are dual-conformally-invariant cross ratios, and can therefore be normalized to unity. We define the concept of a dlog form, and show that it is a feature of the planar integrand as well. This leads to the definition of a pure integrand basis. The proceeding setup is connected to the amplituhedron formulation, and we put forward the hypothesis that the amplitude is determined by zero conditions. Chapter 3 contains the primary computations of the dissertation. This chapter treats. amplitudes in fully nonplanar N = 4 super-Yang-Mills, analyzing the conjecture that they. follow the pattern of having no poles at infinity, can be written in dlog form, and can. be decomposed into a pure integrand basis, with each basis element having unit leading. singularity. Through explicit calculation, we show that this is true for the two-loop fourpoint, three-loop four-point, and two-loop five-point amplitudes, and discuss the features of. each case. We then discuss the zero condition hypothesis, showing explicitly that it holds for the two-loop four-particle amplitude, and showing the set of conditions that fix the amplitude in the three-loop four-particle and two-loop five-particle cases without explicitly performing the fixing. This concludes the body of the dissertation. Two appendices complete the dissertation. Appendix B includes an in-depth discussion of. dlog forms, including purely mathematical examples and a discussion of their appearance in one-loop amplitudes. Finally, Appendix C redoes portions of the analysis of Chapter 3 for the two- and three-loop four-particle amplitudes, but gives representations that are not in a pure integrand basis. Instead diagram symmetry is imposed on the basis elements, and diagrams that lack maximal cuts are pushed into maximal-cut diagrams. This gives representations closer in spirit to the previously-constructed representations of these amplitudes, such as the BCJ representations. It also highlights the role of color Jacobi identities and the freedom in the amplitude representation they can generate, and contains an explicit discussion of these features that is unpublished elsewhere.

Toward a holographic theory for general spacetimes

NASA Astrophysics Data System (ADS)

Nomura, Yasunori; Salzetta, Nico; Sanches, Fabio; Weinberg, Sean J.

2017-04-01

We study a holographic theory of general spacetimes that does not rely on the existence of asymptotic regions. This theory is to be formulated in a holographic space. When a semiclassical description is applicable, the holographic space is assumed to be a holographic screen: a codimension-1 surface that is capable of encoding states of the gravitational spacetime. Our analysis is guided by conjectured relationships between gravitational spacetime and quantum entanglement in the holographic description. To understand basic features of this picture, we catalog predictions for the holographic entanglement structure of cosmological spacetimes. We find that qualitative features of holographic entanglement entropies for such spacetimes differ from those in AdS/CFT but that the former reduce to the latter in the appropriate limit. The Hilbert space of the theory is analyzed, and two plausible structures are found: a direct-sum and "spacetime-equals-entanglement" structure. The former preserves a naive relationship between linear operators and observable quantities, while the latter respects a more direct connection between holographic entanglement and spacetime. We also discuss the issue of selecting a state in quantum gravity, in particular how the state of the multiverse may be selected in the landscape.

Rotor design optimization using a free wake analysis

NASA Technical Reports Server (NTRS)

Quackenbush, Todd R.; Boschitsch, Alexander H.; Wachspress, Daniel A.; Chua, Kiat

1993-01-01

The aim of this effort was to develop a comprehensive performance optimization capability for tiltrotor and helicopter blades. The analysis incorporates the validated EHPIC (Evaluation of Hover Performance using Influence Coefficients) model of helicopter rotor aerodynamics within a general linear/quadratic programming algorithm that allows optimization using a variety of objective functions involving the performance. The resulting computer code, EHPIC/HERO (HElicopter Rotor Optimization), improves upon several features of the previous EHPIC performance model and allows optimization utilizing a wide spectrum of design variables, including twist, chord, anhedral, and sweep. The new analysis supports optimization of a variety of objective functions, including weighted measures of rotor thrust, power, and propulsive efficiency. The fundamental strength of the approach is that an efficient search for improved versions of the baseline design can be carried out while retaining the demonstrated accuracy inherent in the EHPIC free wake/vortex lattice performance analysis. Sample problems are described that demonstrate the success of this approach for several representative rotor configurations in hover and axial flight. Features that were introduced to convert earlier demonstration versions of this analysis into a generally applicable tool for researchers and designers is also discussed.

Improved disparity map analysis through the fusion of monocular image segmentations

NASA Technical Reports Server (NTRS)

Perlant, Frederic P.; Mckeown, David M.

1991-01-01

The focus is to examine how estimates of three dimensional scene structure, as encoded in a scene disparity map, can be improved by the analysis of the original monocular imagery. The utilization of surface illumination information is provided by the segmentation of the monocular image into fine surface patches of nearly homogeneous intensity to remove mismatches generated during stereo matching. These patches are used to guide a statistical analysis of the disparity map based on the assumption that such patches correspond closely with physical surfaces in the scene. Such a technique is quite independent of whether the initial disparity map was generated by automated area-based or feature-based stereo matching. Stereo analysis results are presented on a complex urban scene containing various man-made and natural features. This scene contains a variety of problems including low building height with respect to the stereo baseline, buildings and roads in complex terrain, and highly textured buildings and terrain. The improvements are demonstrated due to monocular fusion with a set of different region-based image segmentations. The generality of this approach to stereo analysis and its utility in the development of general three dimensional scene interpretation systems are also discussed.

Modeling of direct wafer bonding: Effect of wafer bow and etch patterns

NASA Astrophysics Data System (ADS)

Turner, K. T.; Spearing, S. M.

2002-12-01

Direct wafer bonding is an important technology for the manufacture of silicon-on-insulator substrates and microelectromechanical systems. As devices become more complex and require the bonding of multiple patterned wafers, there is a need to understand the mechanics of the bonding process. A general bonding criterion based on the competition between the strain energy accumulated in the wafers and the surface energy that is dissipated as the bond front advances is developed. The bonding criterion is used to examine the case of bonding bowed wafers. An analytical expression for the strain energy accumulation rate, which is the quantity that controls bonding, and the final curvature of a bonded stack is developed. It is demonstrated that the thickness of the wafers plays a large role and bonding success is independent of wafer diameter. The analytical results are verified through a finite element model and a general method for implementing the bonding criterion numerically is presented. The bonding criterion developed permits the effect of etched features to be assessed. Shallow etched patterns are shown to make bonding more difficult, while it is demonstrated that deep etched features can facilitate bonding. Model results and their process design implications are discussed in detail.

Pathophysiology of Tumor Neovascularization

PubMed Central

Furuya, Mitsuko; Nishiyama, Mariko; Kasuya, Yoshitoshi; Kimura, Sadao; Ishikura, Hiroshi

2005-01-01

Neovascularization is essential to the process of development and differentiation of tissues in the vertebrate embryo, and is also involved in a wide variety of physiological and pathological conditions in adults, including wound repair, metabolic diseases, inflammation, cardiovascular disorders, and tumor progression. Thanks to cumulative studies on vasculature, new therapeutic approaches have been opened for us to some life-threatening diseases by controlling angiogenesis in the affected organs. In cancer therapy, for example, modulation of factors responsible for tumor angiogenesis may be beneficial in inhibiting of tumor progression. Several antiangiogenic approaches are currently under preclinical trial. However, the mechanisms of neovascularization in tumors are complicated and each tumor shows unique features in its vasculature, depending on tissue specificity, angiogenic micromilieu, grades and stages, host immunity, and so on. For better understanding and effective therapeutic approaches, it is important to clarify both the general mechanism of angiogenic events and the disease-specific mechanism of neovascularization. This review discusses the general features of angiogenesis under physiological and pathological conditions, mainly in tumor progression. In addition, recent topics such as contribution of the endothelial progenitor cells, tumor vasculogenic mimicry, markers for tumor-derived endothelial cells and pericytes, and angiogenic/angiostatic chemokines are summarized. PMID:17315600

General fusion approaches for the age determination of latent fingerprint traces: results for 2D and 3D binary pixel feature fusion

NASA Astrophysics Data System (ADS)

Merkel, Ronny; Gruhn, Stefan; Dittmann, Jana; Vielhauer, Claus; Bräutigam, Anja

2012-03-01

Determining the age of latent fingerprint traces found at crime scenes is an unresolved research issue since decades. Solving this issue could provide criminal investigators with the specific time a fingerprint trace was left on a surface, and therefore would enable them to link potential suspects to the time a crime took place as well as to reconstruct the sequence of events or eliminate irrelevant fingerprints to ensure privacy constraints. Transferring imaging techniques from different application areas, such as 3D image acquisition, surface measurement and chemical analysis to the domain of lifting latent biometric fingerprint traces is an upcoming trend in forensics. Such non-destructive sensor devices might help to solve the challenge of determining the age of a latent fingerprint trace, since it provides the opportunity to create time series and process them using pattern recognition techniques and statistical methods on digitized 2D, 3D and chemical data, rather than classical, contact-based capturing techniques, which alter the fingerprint trace and therefore make continuous scans impossible. In prior work, we have suggested to use a feature called binary pixel, which is a novel approach in the working field of fingerprint age determination. The feature uses a Chromatic White Light (CWL) image sensor to continuously scan a fingerprint trace over time and retrieves a characteristic logarithmic aging tendency for 2D-intensity as well as 3D-topographic images from the sensor. In this paper, we propose to combine such two characteristic aging features with other 2D and 3D features from the domains of surface measurement, microscopy, photography and spectroscopy, to achieve an increase in accuracy and reliability of a potential future age determination scheme. Discussing the feasibility of such variety of sensor devices and possible aging features, we propose a general fusion approach, which might combine promising features to a joint age determination scheme in future. We furthermore demonstrate the feasibility of the introduced approach by exemplary fusing the binary pixel features based on 2D-intensity and 3D-topographic images of the mentioned CWL sensor. We conclude that a formula based age determination approach requires very precise image data, which cannot be achieved at the moment, whereas a machine learning based classification approach seems to be feasible, if an adequate amount of features can be provided.

Identifying key features of effective active learning: the effects of writing and peer discussion.

PubMed

Linton, Debra L; Pangle, Wiline M; Wyatt, Kevin H; Powell, Karli N; Sherwood, Rachel E

2014-01-01

We investigated some of the key features of effective active learning by comparing the outcomes of three different methods of implementing active-learning exercises in a majors introductory biology course. Students completed activities in one of three treatments: discussion, writing, and discussion + writing. Treatments were rotated weekly between three sections taught by three different instructors in a full factorial design. The data set was analyzed by generalized linear mixed-effect models with three independent variables: student aptitude, treatment, and instructor, and three dependent (assessment) variables: change in score on pre- and postactivity clicker questions, and coding scores on in-class writing and exam essays. All independent variables had significant effects on student performance for at least one of the dependent variables. Students with higher aptitude scored higher on all assessments. Student scores were higher on exam essay questions when the activity was implemented with a writing component compared with peer discussion only. There was a significant effect of instructor, with instructors showing different degrees of effectiveness with active-learning techniques. We suggest that individual writing should be implemented as part of active learning whenever possible and that instructors may need training and practice to become effective with active learning. © 2014 D. L. Linton et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

Translational value of animal models of obesity-Focus on dogs and cats.

PubMed

Osto, Melania; Lutz, Thomas A

2015-07-15

A prolonged imbalance between a relative increase in energy intake over a decrease in energy expenditure results in the development of obesity; extended periods of a positive energy balance eventually lead to the accumulation of abnormally high amounts of fat in adipose tissue but also in other organs. Obesity is considered a clinical state of impaired general heath in which the excessive increase in adipose tissue mass may be associated with metabolic disorders such as type 2 diabetes mellitus, hyperlipidemia, hypertension and cardiovascular diseases. This review discusses briefly the use of animal models for the study of obesity and its comorbidities. Generally, most studies are performed with rodents, such as diet induced obesity and genetic models. Here, we focus specifically on two different species, namely dogs and cats. Obese dogs and cats show many features of human obesity. Interestingly, however, dogs and cats differ from each other in certain aspects because even though obese dogs may become insulin resistant, this does not result in the development of diabetes mellitus. In fact, diabetes in dogs is typically not associated with obesity because dogs present a type 1 diabetes-like syndrome. On the other hand, obese cats often develop diabetes mellitus which shares many features with human type 2 diabetes; feline and human diabetes are similar in respect to their pathophysiology, underlying risk factors and treatment strategies. Our review discusses genetic and endocrine factors in obesity, discusses obesity induced changes in lipid metabolism and includes some recent findings on the role of gut microbiota in obesity. Compared to research in rodent models, the array of available techniques and tools is unfortunately still rather limited in dogs and cats. Hence, even though physiological and pathophysiological phenomena are well described in dogs and cats, the underlying mechanisms are often not known and studies investigating causality specifically are scarce. Copyright © 2015 Elsevier B.V. All rights reserved.

The origin of the bifurcating style in Asteraceae (Compositae).

PubMed

Katinas, Liliana; Hernández, Marcelo P; Arambarri, Ana M; Funk, Vicki A

2016-05-01

The plant family Asteraceae (Compositae) exhibits remarkable morphological variation in the styles of its members. Lack of studies on the styles of the sister families to Asteraceae, Goodeniaceae and Calyceraceae, obscures our understanding of the origin and evolution of this reproductive feature in these groups. The aim of this work was to perform a comparative study of style morphology and to discuss the relevance of important features in the evolution of Asteraceae and its sister families. The histochemistry, venation and general morphology of the styles of members of Goodeniaceae, Calyceraceae and early branching lineages of Asteraceae were analysed and put in a phylogenetic framework to discuss the relevance of style features in the evolution of these families. The location of lipophilic substances allowed differentiation of receptive from non-receptive style papillae, and the style venation in Goodeniaceae and Calyceraceae proved to be distinctive. There were several stages of style evolution from Goodeniaceae to Asteraceae involving connation and elongation of veins, development of bilobation from an initially cup-shaped style, and a redistribution of the receptive and non-receptive papillae. These developments resulted in bifurcation in the styles of Asteraceae, with each branch face having a different function, and it is suggested here as a mechanism that promoted outcrossing, which in turn led to the great diversification in the family. © The Author 2016. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

White perovskite based lighting devices.

PubMed

Bidikoudi, M; Fresta, E; Costa, R D

2018-06-28

Hybrid organic-inorganic and all-inorganic metal halide perovskites have been one of the most intensively studied materials during the last few years. In particular, research focusing on understanding how to tune the photoluminescence features and to apply perovskites to optoelectronic applications has led to a myriad of new materials featuring high photoluminescence quantum yields covering the whole visible range, as well as devices with remarkable performances. Having already established their successful incorporation in highly efficient solar cells, the next step is to tackle the challenges in solid-state lighting (SSL) devices. Here, the most prominent is the preparation of white-emitting devices. Herein, we have provided a comprehensive view of the route towards perovskite white lighting devices, including thin film light-emitting diodes (PeLEDs) and hybrid LEDs (HLEDs), using perovskite based color down-converting coatings. While synthesis and photoluminescence features are briefly discussed, we focus on highlighting the major achievements and limitations in white devices. Overall, we expect that this review will provide the reader a general overview of the current state of perovskite white SSL, paving the way towards new breakthroughs in the near future.

Some design constraints required for the assembly of software components: The incorporation of atomic abstract types into generically structured abstract types

NASA Technical Reports Server (NTRS)

Johnson, Charles S.

1986-01-01

It is nearly axiomatic, that to take the greatest advantage of the useful features available in a development system, and to avoid the negative interactions of those features, requires the exercise of a design methodology which constrains their use. A major design support feature of the Ada language is abstraction: for data, functions processes, resources, and system elements in general. Atomic abstract types can be created in packages defining those private types and all of the overloaded operators, functions, and hidden data required for their use in an application. Generically structured abstract types can be created in generic packages defining those structured private types, as buildups from the user-defined data types which are input as parameters. A study is made of the design constraints required for software incorporating either atomic or generically structured abstract types, if the integration of software components based on them is to be subsequently performed. The impact of these techniques on the reusability of software and the creation of project-specific software support environments is also discussed.

Nanoparticles for Cardiovascular Imaging and Therapeutic Delivery, Part 1: Compositions and Features.

PubMed

Stendahl, John C; Sinusas, Albert J

2015-10-01

Imaging agents made from nanoparticles are functionally versatile and have unique properties that may translate to clinical utility in several key cardiovascular imaging niches. Nanoparticles exhibit size-based circulation, biodistribution, and elimination properties different from those of small molecules and microparticles. In addition, nanoparticles provide versatile platforms that can be engineered to create both multimodal and multifunctional imaging agents with tunable properties. With these features, nanoparticulate imaging agents can facilitate fusion of high-sensitivity and high-resolution imaging modalities and selectively bind tissues for targeted molecular imaging and therapeutic delivery. Despite their intriguing attributes, nanoparticulate imaging agents have thus far achieved only limited clinical use. The reasons for this restricted advancement include an evolving scope of applications, the simplicity and effectiveness of existing small-molecule agents, pharmacokinetic limitations, safety concerns, and a complex regulatory environment. This review describes general features of nanoparticulate imaging agents and therapeutics and discusses challenges associated with clinical translation. A second, related review to appear in a subsequent issue of JNM highlights nuclear-based nanoparticulate probes in preclinical cardiovascular imaging. © 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

The role of attention in binding visual features in working memory: evidence from cognitive ageing.

PubMed

Brown, Louise A; Brockmole, James R

2010-10-01

Two experiments were conducted to assess the costs of attentional load during a feature (colour-shape) binding task in younger and older adults. Experiment 1 showed that a demanding backwards counting task, which draws upon central executive/general attentional resources, reduced binding to a greater extent than individual feature memory, but the effect was no greater in older than in younger adults. Experiment 2 showed that presenting memory items sequentially rather than simultaneously, such that items are required to be maintained while new representations are created, selectively affects binding performance in both age groups. Although this experiment exhibited an age-related binding deficit overall, both age groups were affected by the attention manipulation to an equal extent. While a role for attentional processes in colour-shape binding was apparent across both experiments, manipulations of attention exerted equal effects in both age groups. We therefore conclude that age-related binding deficits neither emerge nor are exacerbated under conditions of high attentional load. Implications for theories of visual working memory and cognitive ageing are discussed.

Numerical Simulation of The Mediterranean Sea Using Diecast: Interaction Between Basin, Sub-basin and Local Scale Features and Natural Variability.

NASA Astrophysics Data System (ADS)

Fernández, V.; Dietrich, D. E.; Haney, R. L.; Tintoré, J.

In situ and satellite data obtained during the last ten years have shown that the circula- tion in the Mediterranean Sea is extremely complex in space, with significant features ranging from mesoscale to sub-basin and basin scale, and highly variable in time, with mesoscale to seasonal and interannual signals. Also, the steep bottom topography and the variable atmospheric conditions from one sub-basin to another, make the circula- tion to be composed of numerous energetic and narrow coastal currents, density fronts and mesoscale structures that interact at sub-basin scale with the large scale circula- tion. To simulate numerically and better understand these features, besides high grid resolution, a low numerical dispersion and low physical dissipation ocean model is required. We present the results from a 1/8z horizontal resolution numerical simula- tion of the Mediterranean Sea using DieCAST ocean model, which meets the above requirements since it is stable with low general dissipation and uses accurate fourth- order-accurate approximations with low numerical dispersion. The simulations are carried out with climatological surface forcing using monthly mean winds and relax- ation towards climatological values of temperature and salinity. The model reproduces the main features of the large basin scale circulation, as well as the seasonal variabil- ity of sub-basin scale currents that are well documented by observations in straits and channels. In addition, DieCAST brings out natural fronts and eddies that usually do not appear in numerical simulations of the Mediterranean and that lead to a natural interannual variability. The role of this intrinsic variability in the general circulation will be discussed.

IMMAN: free software for information theory-based chemometric analysis.

PubMed

Urias, Ricardo W Pino; Barigye, Stephen J; Marrero-Ponce, Yovani; García-Jacas, César R; Valdes-Martiní, José R; Perez-Gimenez, Facundo

2015-05-01

The features and theoretical background of a new and free computational program for chemometric analysis denominated IMMAN (acronym for Information theory-based CheMoMetrics ANalysis) are presented. This is multi-platform software developed in the Java programming language, designed with a remarkably user-friendly graphical interface for the computation of a collection of information-theoretic functions adapted for rank-based unsupervised and supervised feature selection tasks. A total of 20 feature selection parameters are presented, with the unsupervised and supervised frameworks represented by 10 approaches in each case. Several information-theoretic parameters traditionally used as molecular descriptors (MDs) are adapted for use as unsupervised rank-based feature selection methods. On the other hand, a generalization scheme for the previously defined differential Shannon's entropy is discussed, as well as the introduction of Jeffreys information measure for supervised feature selection. Moreover, well-known information-theoretic feature selection parameters, such as information gain, gain ratio, and symmetrical uncertainty are incorporated to the IMMAN software ( http://mobiosd-hub.com/imman-soft/ ), following an equal-interval discretization approach. IMMAN offers data pre-processing functionalities, such as missing values processing, dataset partitioning, and browsing. Moreover, single parameter or ensemble (multi-criteria) ranking options are provided. Consequently, this software is suitable for tasks like dimensionality reduction, feature ranking, as well as comparative diversity analysis of data matrices. Simple examples of applications performed with this program are presented. A comparative study between IMMAN and WEKA feature selection tools using the Arcene dataset was performed, demonstrating similar behavior. In addition, it is revealed that the use of IMMAN unsupervised feature selection methods improves the performance of both IMMAN and WEKA supervised algorithms. Graphic representation for Shannon's distribution of MD calculating software.

Categorization and reasoning among tree experts: do all roads lead to Rome?

PubMed

Medin, D L; Lynch, E B; Coley, J D; Atran, S

1997-02-01

To what degree do conceptual systems reflect universal patterns of featural covariation in the world (similarity) or universal organizing principles of mind, and to what degree do they reflect specific goals, theories, and beliefs of the categorizer? This question was addressed in experiments concerned with categorization and reasoning among different types of tree experts (e.g., taxonomists, landscape workers, parks maintenance personnel). The results show an intriguing pattern of similarities and differences. Differences in sorting between taxonomists and maintenance workers reflect differences in weighting of morphological features. Landscape workers, in contrast, sort trees into goal-derived categories based on utilitarian concerns. These sorting patterns carry over into category-based reasoning for the taxonomists and maintenance personnel but not the landscape workers. These generalizations interact with taxonomic rank and suggest that the genus (or folk generic) level is relatively and in some cases absolutely privileged. Implications of these findings for theories of categorization are discussed.

Swarms: Optimum aggregations of spacecraft

NASA Technical Reports Server (NTRS)

Mayer, H. L.

1980-01-01

Swarms are aggregations of spacecraft or elements of a space system which are cooperative in function, but physically isolated or only loosely connected. For some missions the swarm configuration may be optimum compared to a group of completely independent spacecraft or a complex rigidly integrated spacecraft or space platform. General features of swarms are induced by considering an ensemble of 26 swarms, examples ranging from Earth centered swarms for commercial application to swarms for exploring minor planets. A concept for a low altitude swarm as a substitute for a space platform is proposed and a preliminary design studied. The salient design feature is the web of tethers holding the 30 km swarm in a rigid two dimensional array in the orbital plane. A mathematical discussion and tutorial in tether technology and in some aspects of the distribution of services (mass, energy, and information to swarm elements) are included.

Musings about beauty.

PubMed

Kintsch, Walter

2012-01-01

In this essay, I explore how cognitive science could illuminate the concept of beauty. Two results from the extensive literature on aesthetics guide my discussion. As the term "beauty" is overextended in general usage, I choose as my starting point the notion of "perfect form." Aesthetic theorists are in reasonable agreement about the criteria for perfect form. What do these criteria imply for mental representations that are experienced as beautiful? Complexity theory can be used to specify constraints on mental representations abstractly formulated as vectors in a high-dimensional space. A central feature of the proposed model is that perfect form depends both on features of the objects or events perceived and on the nature of the encoding strategies or model of the observer. A simple example illustrates the proposed calculations. A number of interesting implications that arise as a consequence of reformulating beauty in this way are noted. Copyright © 2012 Cognitive Science Society, Inc.

Challenges in discriminating profanity from hate speech

NASA Astrophysics Data System (ADS)

Malmasi, Shervin; Zampieri, Marcos

2018-03-01

In this study, we approach the problem of distinguishing general profanity from hate speech in social media, something which has not been widely considered. Using a new dataset annotated specifically for this task, we employ supervised classification along with a set of features that includes ?-grams, skip-grams and clustering-based word representations. We apply approaches based on single classifiers as well as more advanced ensemble classifiers and stacked generalisation, achieving the best result of ? accuracy for this 3-class classification task. Analysis of the results reveals that discriminating hate speech and profanity is not a simple task, which may require features that capture a deeper understanding of the text not always possible with surface ?-grams. The variability of gold labels in the annotated data, due to differences in the subjective adjudications of the annotators, is also an issue. Other directions for future work are discussed.

Contextual interference processing during fast categorisations of facial expressions.

PubMed

Frühholz, Sascha; Trautmann-Lengsfeld, Sina A; Herrmann, Manfred

2011-09-01

We examined interference effects of emotionally associated background colours during fast valence categorisations of negative, neutral and positive expressions. According to implicitly learned colour-emotion associations, facial expressions were presented with colours that either matched the valence of these expressions or not. Experiment 1 included infrequent non-matching trials and Experiment 2 a balanced ratio of matching and non-matching trials. Besides general modulatory effects of contextual features on the processing of facial expressions, we found differential effects depending on the valance of target facial expressions. Whereas performance accuracy was mainly affected for neutral expressions, performance speed was specifically modulated by emotional expressions indicating some susceptibility of emotional expressions to contextual features. Experiment 3 used two further colour-emotion combinations, but revealed only marginal interference effects most likely due to missing colour-emotion associations. The results are discussed with respect to inherent processing demands of emotional and neutral expressions and their susceptibility to contextual interference.

A framework for treating DSM-5 alternative model for personality disorder features.

PubMed

Hopwood, Christopher J

2018-04-15

Despite its demonstrated empirical superiority over the DSM-5 Section 2 categorical model of personality disorders for organizing the features of personality pathology, limitations remain with regard to the translation of the DSM-5 Section 3 alternative model of personality disorders (AMPD) to clinical practice. The goal of this paper is to outline a general and preliminary framework for approaching treatment from the perspective of the AMPD. Specific techniques are discussed for the assessment and treatment of both Criterion A personality dysfunction and Criterion B maladaptive traits. A concise and step-by-step model is presented for clinical decision making with the AMPD, in the hopes of offering clinicians a framework for treating personality pathology and promoting further research on the clinical utility of the AMPD. Copyright © 2018 John Wiley & Sons, Ltd. Copyright © 2018 John Wiley & Sons, Ltd.

How Preferences for Public Participation are Linked to Perceptions of the Context, Preferences for Outcomes, and Individual Characteristics

NASA Astrophysics Data System (ADS)

Tuler, Seth; Webler, Thomas

2010-08-01

Practitioners and stakeholders involved in environmental and risk assessment and decision-making efforts have access to a growing list of policies and guidance for implementing good process. The advice is often general. There is little understanding of how situation specific features are relevant in new circumstances. In a series of ten case studies we investigated how people’s (a) perceptions of the context, (b) preferences for outcomes, and (c) affiliations, experiences and motivations are related to their preferences for process features in a particular situation. The cases are in three policy areas: watershed management, forestry management, and clean-up and public health management of radioactively contaminated sites. We conclude this paper with a discussion of how the results can inform process design. Process design should be based on a diagnostic approach that specifically assesses relevant situational characteristics.

Use of fuzzy sets in modeling of GIS objects

NASA Astrophysics Data System (ADS)

Mironova, Yu N.

2018-05-01

The paper discusses modeling and methods of data visualization in geographic information systems. Information processing in Geoinformatics is based on the use of models. Therefore, geoinformation modeling is a key in the chain of GEODATA processing. When solving problems, using geographic information systems often requires submission of the approximate or insufficient reliable information about the map features in the GIS database. Heterogeneous data of different origin and accuracy have some degree of uncertainty. In addition, not all information is accurate: already during the initial measurements, poorly defined terms and attributes (e.g., "soil, well-drained") are used. Therefore, there are necessary methods for working with uncertain requirements, classes, boundaries. The author proposes using spatial information fuzzy sets. In terms of a characteristic function, a fuzzy set is a natural generalization of ordinary sets, when one rejects the binary nature of this feature and assumes that it can take any value in the interval.

Propofol-Related Infusion Syndrome in Critically Ill Pediatric Patients: Coincidence, Association, or Causation?

PubMed Central

Timpe, Erin M.; Eichner, Samantha F.; Phelps, Stephanie J.

2006-01-01

Over the past two decades numerous reports have described the development of a propofol-related infusion syndrome (PRIS) in critically ill adult and pediatric patients who received continuous infusion propofol for anesthesia or sedation. The syndrome is generally characterized by progressive metabolic acidosis, hemodynamic instability and bradyarrhythmias that are refractory to aggressive pharmacological treatments. PRIS may occur with or without the presence of hepatomegaly, rhabdomyolysis or lipemia. To date, the medical literature contains accounts of 20 deaths in critically ill pediatric patients who developed features consistent with PRIS. These reports have generated considerable discussion and debate regarding the relationship, if any, between propofol and a constellation of clinical symptoms and features that have been attributed to its use in critically ill pediatric patients. This paper reviews the literature concerning PRIS, its clinical presentation, proposed mechanisms for the syndrome, and potential management should the syndrome occur. PMID:23118644

A new Gaussian MCTDH program: Implementation and validation on the levels of the water and glycine molecules

NASA Astrophysics Data System (ADS)

Skouteris, D.; Barone, V.

2014-06-01

We report the main features of a new general implementation of the Gaussian Multi-Configuration Time-Dependent Hartree model. The code allows effective computations of time-dependent phenomena, including calculation of vibronic spectra (in one or more electronic states), relative state populations, etc. Moreover, by expressing the Dirac-Frenkel variational principle in terms of an effective Hamiltonian, we are able to provide a new reliable estimate of the representation error. After validating the code on simple one-dimensional systems, we analyze the harmonic and anharmonic vibrational spectra of water and glycine showing that reliable and converged energy levels can be obtained with reasonable computing resources. The data obtained on water and glycine are compared with results of previous calculations using the vibrational second-order perturbation theory method. Additional features and perspectives are also shortly discussed.

Discovery of multi-ring basins - Gestalt perception in planetary science

NASA Technical Reports Server (NTRS)

Hartmann, W. K.

1981-01-01

Early selenographers resolved individual structural components of multi-ring basin systems but missed the underlying large-scale multi-ring basin patterns. The recognition of multi-ring basins as a general class of planetary features can be divided into five steps. Gilbert (1893) took a first step in recognizing radial 'sculpture' around the Imbrium basin system. Several writers through the 1940's rediscovered the radial sculpture and extended this concept by describing concentric rings around several circular maria. Some reminiscences are given about the fourth step - discovery of the Orientale basin and other basin systems by rectified lunar photography at the University of Arizona in 1961-62. Multi-ring basins remained a lunar phenomenon until the fifth step - discovery of similar systems of features on other planets, such as Mars (1972), Mercury (1974), and possibly Callisto and Ganymede (1979). This sequence is an example of gestalt recognition whose implications for scientific research are discussed.

Alternating current circuit theory and pulsed NMR (Nuclear Magnetic Resonance)

NASA Astrophysics Data System (ADS)

Gerstein, B. C.

1987-06-01

Pulsed NMR, by definition, deals with time varying excitations. These excitations, supplied by resonant circuits which provide a pulse of radiofrequency (frequencies in the megahertz region) power to a resonant circuit containing, among other things, a coil of wire, or inductor, in which a sample under investigation is placed for purposes of the nuclear magnetic resonance experiment. There are therefore two features of the pulse NMR experiment. First is the fact that we have available a source of continuous wave (CW) alternating current at some angular frequency, omega, measured in radians per second. This source is generally supplied by an ultrastable device called a frequency synthesizer. The second feature of the pulsed NMR experiment is that the sample is not continuously irradiated, but a pulse of radiofrequency oscillation is applied to the sample. This report discusses alternating current theory, resonant circuits and the equipment used in this experiment.

Co-occurring mental health and substance use problems in offenders: implications for risk assessment.

PubMed

Ruiz, Mark A; Douglas, Kevin S; Edens, John F; Nikolova, Natalia L; Lilienfeld, Scott O

2012-03-01

We undertook a secondary data analysis to study issues relevant to co-occurring mental health and substance disorder in a combined sample of offenders (N = 3,197). Using the Personality Assessment Inventory, we compared the frequency of depressive, traumatic stress, and personality disorder symptom elevations across offenders with and without substance problems, identified the extent to which co-occurring problems were accompanied by risk factors for suicide and aggression, and tested for gender differences. Offenders with substance problems were more likely than others to have increased mental health problems and risk factors for suicide or aggression. Women with substance problems, compared with men, had higher depression, traumatic stress, and borderline features, in addition to lower antisocial features. The frequency with which suicide and aggression risk factors were associated with mental health problems was generally similar across men and women. Measurement issues relevant to co-occurring disorder and risk assessment are discussed.

Primordial inhomogeneities in the expanding universe. II - General features of spherical models at late times

NASA Technical Reports Server (NTRS)

Olson, D. W.; Silk, J.

1979-01-01

This paper studies the density profile that forms around a spherically symmetric bound central core immersed in a homogeneous-background k = 0 or k = -1 Friedmann-Robertson-Walker cosmological model, with zero pressure. Although the density profile in the linearized regime is almost arbitrary, in the nonlinear regime certain universal features of the density profile are obtained that are independent of the details of the initial conditions. The formation of 'halos' ('holes') with densities greater than (less than) the average cosmological density is discussed. It is shown that in most regions 'halos' form, and universal values are obtained for the slope of the ln (density)-ln (radius) profile in those 'halos' at late times, independently of the shape of the initial density profile. Restrictions are derived on where it is possible for 'holes' to exist at late times and on how such 'holes' must have evolved.

Perforated peptic ulcer in an adolescent girl.

PubMed

Schwartz, Shepard; Edden, Yair; Orkin, Boris; Erlichman, Matityahu

2012-07-01

A perforated peptic ulcer in a child is a rare entity. Severe abdominal pain in an ill-appearing child with a rigid abdomen and possibly with signs of shock is the typical presenting feature of this life-threatening complication of peptic ulcer disease. We present a case of a 14.5-year-old adolescent girl who developed abdominal and shoulder pain that resolved after 1 day. She was then completely well for 2 days until the abdominal and shoulder pain recurred. On examination, she appeared well, but in pain. A chest radiograph revealed a large pneumoperitoneum. She underwent emergent laparoscopic omental patch repair of a perforated ulcer on the anterior wall of her stomach. Result of a urea breath test to detect Helicobacter pylori was negative. The differential diagnosis of pneumoperitoneum in children is discussed, as are childhood perforated peptic ulcer in general, and the unique clinical features present in this case in particular.

Presence of pro-tobacco messages on the Web.

PubMed

Hong, Traci; Cody, Michael J

2002-01-01

Ignored in the finalized Master Settlement Agreement (National Association of Attorneys General, 1998), the unmonitored, unregulated World Wide Web (Web) can operate as a major vehicle for delivering pro-tobacco messages, images, and products to millions of young consumers. A content analysis of 318 randomly sampled pro-tobacco Web sites revealed that tobacco has a pervasive presence on the Web, especially on e-commerce sites and sites featuring hobbies, recreation, and "fetishes." Products can be ordered online on nearly 50% of the sites, but only 23% of the sites included underage verification. Further, only 11% of these sites contain health warnings. Instead, pro-tobacco sites frequently associate smoking with "glamorous" and "alternative" lifestyles, and with images of young males and young (thin, attractive) females. Finally, many of the Web sites offered interactive site features that are potentially appealing to young Web users. Recommendations for future research and counterstrategies are discussed.

Neural dynamics underlying attentional orienting to auditory representations in short-term memory.

PubMed

Backer, Kristina C; Binns, Malcolm A; Alain, Claude

2015-01-21

Sounds are ephemeral. Thus, coherent auditory perception depends on "hearing" back in time: retrospectively attending that which was lost externally but preserved in short-term memory (STM). Current theories of auditory attention assume that sound features are integrated into a perceptual object, that multiple objects can coexist in STM, and that attention can be deployed to an object in STM. Recording electroencephalography from humans, we tested these assumptions, elucidating feature-general and feature-specific neural correlates of auditory attention to STM. Alpha/beta oscillations and frontal and posterior event-related potentials indexed feature-general top-down attentional control to one of several coexisting auditory representations in STM. Particularly, task performance during attentional orienting was correlated with alpha/low-beta desynchronization (i.e., power suppression). However, attention to one feature could occur without simultaneous processing of the second feature of the representation. Therefore, auditory attention to memory relies on both feature-specific and feature-general neural dynamics. Copyright © 2015 the authors 0270-6474/15/351307-12$15.00/0.

Review of general algorithmic features for genome assemblers for next generation sequencers.

PubMed

Wajid, Bilal; Serpedin, Erchin

2012-04-01

In the realm of bioinformatics and computational biology, the most rudimentary data upon which all the analysis is built is the sequence data of genes, proteins and RNA. The sequence data of the entire genome is the solution to the genome assembly problem. The scope of this contribution is to provide an overview on the art of problem-solving applied within the domain of genome assembly in the next-generation sequencing (NGS) platforms. This article discusses the major genome assemblers that were proposed in the literature during the past decade by outlining their basic working principles. It is intended to act as a qualitative, not a quantitative, tutorial to all working on genome assemblers pertaining to the next generation of sequencers. We discuss the theoretical aspects of various genome assemblers, identifying their working schemes. We also discuss briefly the direction in which the area is headed towards along with discussing core issues on software simplicity. Copyright © 2012 Beijing Institute of Genomics, Chinese Academy of Sciences. Published by Elsevier Ltd. All rights reserved.

Systematic evaluation of deep learning based detection frameworks for aerial imagery

NASA Astrophysics Data System (ADS)

Sommer, Lars; Steinmann, Lucas; Schumann, Arne; Beyerer, Jürgen

2018-04-01

Object detection in aerial imagery is crucial for many applications in the civil and military domain. In recent years, deep learning based object detection frameworks significantly outperformed conventional approaches based on hand-crafted features on several datasets. However, these detection frameworks are generally designed and optimized for common benchmark datasets, which considerably differ from aerial imagery especially in object sizes. As already demonstrated for Faster R-CNN, several adaptations are necessary to account for these differences. In this work, we adapt several state-of-the-art detection frameworks including Faster R-CNN, R-FCN, and Single Shot MultiBox Detector (SSD) to aerial imagery. We discuss adaptations that mainly improve the detection accuracy of all frameworks in detail. As the output of deeper convolutional layers comprise more semantic information, these layers are generally used in detection frameworks as feature map to locate and classify objects. However, the resolution of these feature maps is insufficient for handling small object instances, which results in an inaccurate localization or incorrect classification of small objects. Furthermore, state-of-the-art detection frameworks perform bounding box regression to predict the exact object location. Therefore, so called anchor or default boxes are used as reference. We demonstrate how an appropriate choice of anchor box sizes can considerably improve detection performance. Furthermore, we evaluate the impact of the performed adaptations on two publicly available datasets to account for various ground sampling distances or differing backgrounds. The presented adaptations can be used as guideline for further datasets or detection frameworks.

Broadening and collisional interference of lines in the IR spectra of ammonia. Theory

NASA Astrophysics Data System (ADS)

Cherkasov, M. R.

2016-06-01

The general theory of relaxation spectral shape parameters in the impact approximation (M. R. Cherkasov, J. Quant. Spectrosc. Radiat. Transfer 141, 73 (2014)) is adapted to the case of line broadening of infrared spectra of ammonia. Specific features of line broadening of parallel and perpendicular bands are discussed. It is shown that in both cases the spectrum consists of independently broadened singlets and doublets; however, the components of doublets can be affected by collisional interference. The paper is the first part of a cycle of studies devoted to the problems of spectral line broadening of ammonia.

[Use of blue and green systems of image visualization in roentgenology].

PubMed

Riuduger, Iu G

2004-01-01

The main peculiarities of two image visualization systems related with the specificity of intensifying screens and of radiographic films in each of them are discussed. Specific features of kinetic development of modern orthochromatic general-purpose radiographic films were studied versus those of the traditional films; differences related with radiation hardness of some of the intensifying screen manufactured in Russia were investigated. Some practical advice was suggested on the basis of a conducted analysis of the "green" system specificity; such advice provides for reorienting the X-ray examination room, in Russia, for gadolinium screens and modern radiography films.

Design of an airborne launch vehicle for an air launched space booster

NASA Technical Reports Server (NTRS)

Chao, Chin; Choi, Rich; Cohen, Scott; Dumont, Brian; Gibin, Mauricius; Jorden, Rob; Poth, Stefan

1993-01-01

A conceptual design is presented for a carrier vehicle for an air launched space booster. This airplane is capable of carrying a 500,000 pound satellite launch system to an altitude over 40,000 feet for launch. The airplane features a twin fuselage configuration for improved payload and landing gear integration, a high aspect ratio wing for maneuverability at altitude, and is powered by six General Electric GE-90 engines. The analysis methods used and the systems employed in the airplane are discussed. Launch costs are expected to be competitive with existing launch systems.

Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies.

PubMed

Yap, Alpha S; Gomez, Guillermo A; Parton, Robert G

2015-10-12

This Perspective considers how classical cadherin cell-cell adhesion receptors are organized at the nanoscale to generate lateral clusters. Recent advances in optical microscopy reveal that clustering constitutes a general feature of cadherin organization, but one that takes diverse forms. Here we consider the molecular mechanisms responsible for cadherin clustering and their functional implications. We frame our discussion in light of what is known about how nanoscale organization is conferred upon the plasma membrane, through protein-protein interactions, regulation of the cortical actin cytoskeleton, and the lipid environment of the membrane. Copyright © 2015 Elsevier Inc. All rights reserved.

Fast trimers in a one-dimensional extended Fermi-Hubbard model

NASA Astrophysics Data System (ADS)

Dhar, A.; Törmä, P.; Kinnunen, J. J.

2018-04-01

We consider a one-dimensional two-component extended Fermi-Hubbard model with nearest-neighbor interactions and mass imbalance between the two species. We study the binding energy of trimers, various observables for detecting them, and expansion dynamics. We generalize the definition of the trimer gap to include the formation of different types of clusters originating from nearest-neighbor interactions. Expansion dynamics reveal rapidly propagating trimers, with speeds exceeding doublon propagation in the strongly interacting regime. We present a simple model for understanding this unique feature of the movement of the trimers, and we discuss the potential for experimental realization.

Showcasing a profession: getting nursing on the newsstand.

PubMed

Hobdell, E F; Slusser, M; Patterson, J; Burgess, E

1991-01-01

Interacting with the media is a method of showcasing the nursing profession. Clinical nurse specialists (CNSs) have a variety of opportunities available for these interactions: appearing on television, participating in a radio program or writing to the media. A survey completed by the authors indicated that CNSs had many media interactions, yet overall, only 17% of all nurses surveyed used writing. This paper begins by discussing where to publish and how to prepare and target the audience. General and specific guidelines for publishing feature articles, health tips, letters to the editor, and other publishing possibilities are presented.

Why is the World four-dimensional? Hermann Weyl’s 1955 argument and the topology of causation

NASA Astrophysics Data System (ADS)

De Bianchi, Silvia

2017-08-01

This paper approaches the question of space dimensionality by discussing a neglected argument proposed by Hermann Weyl in 1955. In Why is the World Four-Dimensional? (1955), Weyl offered a different argument from the one generally attributed to him and presented in Raum-Zeit-Materie. In the first sections of the paper, this new argument and its features are spelled-out, and in the last section, I shall develop some useful remarks on the concept of topology of causation that can still inform our reflection on the dimensionality of the world.

Ultra-relativistic Au+Au and d+Au collisions:

NASA Astrophysics Data System (ADS)

Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Chai, Z.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Hauer, M.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; McLeod, D.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Seals, H.; Sedykh, I.; Skulski, W.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Tang, J.-L.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Wenger, E.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wysłouch, B.

In this talk I will review PHOBOS data on charged particle multiplicities, obtained in Au+Au and d+Au collisions at RHIC. The general features of the Au+Au pseudorapidity distributions results will be discussed and compared to those of /line{p}p collisions. The total charged particle multiplicity, scaled by the number of participant pairs, is observed to be about 40% higher in Au+Au collisions than in /line{p}p and d+Au systems, but, surprisingly at the same level of e+e- collisions. Limiting fragmentation scaling is seen to be obeyed in Au+Au collisions.

Design of an airborne launch vehicle for an air launched space booster

NASA Astrophysics Data System (ADS)

Chao, Chin; Choi, Rich; Cohen, Scott; Dumont, Brian; Gibin, Mauricius; Jorden, Rob; Poth, Stefan

1993-12-01

A conceptual design is presented for a carrier vehicle for an air launched space booster. This airplane is capable of carrying a 500,000 pound satellite launch system to an altitude over 40,000 feet for launch. The airplane features a twin fuselage configuration for improved payload and landing gear integration, a high aspect ratio wing for maneuverability at altitude, and is powered by six General Electric GE-90 engines. The analysis methods used and the systems employed in the airplane are discussed. Launch costs are expected to be competitive with existing launch systems.

Leptospirosis complicating with acute large bowel gangrene: a case report.

PubMed

Zamri, Z; Shaker, A H; Razman, J

2012-01-01

Leptospirosis is a zoonosis with worldwide distribution. It is often referred to as swineherd's disease, swamp fever or mud fever. In recent years there is increase incidence in leptospirosis in human. The incidence varies from sporadic in temperate zones to endemic in the tropical countries. Leptospirosis generally present with features of bacterial infection in acute phase following with multi organs complications. Acute bowel ischaemia with perforation following leptospirosis is a rare presentation . To the best of our knowledge, this is the first case report of such condition. The surgical management of this rare incidence will be discussed.

A review of clinical practice guidelines for lung cancer

PubMed Central

Ball, David; Silvestri, Gerard A.

2013-01-01

Clinical practice guidelines are important evidence-based resources to guide complex clinical decision making. However, it is challenging for health professionals to keep abreast available guidelines and to know how and where to access relevant guidelines. This review examines currently available guidelines for lung cancer published in the English language. Important key features are listed for each identified guideline. The methodology, approaches to dissemination and implementation, and associated resources are summarised. General challenges in the area of guideline development are highlighted. The potential to collaborate more widely across lung cancer guideline developers by sharing literature searches and assessments is discussed. PMID:24163752

Nonlinear low frequency (LF) waves - Comets and foreshock phenomena

NASA Technical Reports Server (NTRS)

Tsurutani, Bruce T.

1991-01-01

A review is conducted of LF wave nonlinear properties at comets and in the earth's foreshock, engaging such compelling questions as why there are no cometary cyclotron waves, the physical mechanism responsible for 'dispersive whiskers', and the character of a general description of linear waves. Attention is given to the nonlinear properties of LF waves, whose development is illustrated by examples of waves and their features at different distances from the comet, as well as by computer simulation results. Also discussed is a curious wave mode detected from Comet Giacobini-Zinner, both at and upstream of the bow shock/wave.

Squeezed states: A geometric framework

NASA Technical Reports Server (NTRS)

Ali, S. T.; Brooke, J. A.; Gazeau, J.-P.

1992-01-01

A general definition of squeezed states is proposed and its main features are illustrated through a discussion of the standard optical coherent states represented by 'Gaussian pure states'. The set-up involves representations of groups on Hilbert spaces over homogeneous spaces of the group, and relies on the construction of a square integrable (coherent state) group representation modulo a subgroup. This construction depends upon a choice of a Borel section which has a certain permissible arbitrariness in its selection; this freedom is attributable to a squeezing of the defining coherent states of the representation, and corresponds in this way to a sort of gauging.

Spinning boson stars and Kerr black holes with scalar hair: The effect of self-interactions

NASA Astrophysics Data System (ADS)

Herdeiro, Carlos A. R.; Radu, Eugen; Rúnarsson, Helgi F.

2016-05-01

Self-interacting boson stars (BSs) have been shown to alleviate the astrophysically low maximal mass of their nonself-interacting counterparts. We report some physical features of spinning self-interacting BSs, namely their compactness, the occurrence of ergo-regions and the scalar field profiles, for a sample of values of the coupling parameter. The results agree with the general picture that these BSs are comparatively less compact than the nonself-interacting ones. We also briefly discuss the effect of scalar self-interactions on the properties of Kerr black holes with scalar hair.

Quantum gravity model with fundamental spinor fields

NASA Astrophysics Data System (ADS)

Obukhov, Yu. N.; Hehl, F. W.

2014-01-01

We discuss the possibility that gravitational potentials (metric, coframe and connection) may emerge as composite fields from more fundamental spinor constituents. We use the formalism of Poincaré gauge gravity as an appropriate theoretical scheme for the rigorous development of such an approach. We postulate the constitutive relations of an elastic Cosserat type continuum that models spacetime. These generalized Hooke and MacCullagh type laws consistently take into account the translational and Lorentz rotational deformations, respectively. The resulting theory extends the recently proposed Diakonov model. An intriguing feature of our theory is that in the lowest approximation it reproduces Heisenberg's nonlinear spinor model.

Theory of the Trojan-Horse Method - From the Original Idea to Actual Applications

NASA Astrophysics Data System (ADS)

Typel, Stefan

2018-01-01

The origin and the main features of the Trojan-horse (TH) method are delineated starting with the original idea of Gerhard Baur. Basic theoretical considerations, general experimental conditions and possible problems are discussed. Significant steps in experimental studies towards the implementation of the TH method and the development of the theoretical description are presented. This lead to the successful application of the TH approach by Claudio Spitaleri and his group to determine low-energy cross section that are relevant for astrophysics. An outlook with possible developments in the future are given.

Overview of major hazards. Part 2: Source term; dispersion; combustion; blast, missiles, venting; fire; radiation; runaway reactions; toxic substances; dust explosions

NASA Astrophysics Data System (ADS)

Vilain, J.

Approaches to major hazard assessment and prediction are reviewed. Source term: (phenomenology/modeling of release, influence on early stages of dispersion); dispersion (atmospheric advection, diffusion and deposition, emphasis on dense/cold gases); combustion (flammable clouds and mists covering flash fires, deflagration, transition to detonation; mostly unconfined/partly confined situations); blast formation, propagation, interaction with structures; catastrophic fires (pool fires, torches and fireballs; highly reactive substances) runaway reactions; features of more general interest; toxic substances, excluding toxicology; and dust explosions (phenomenology and protective measures) are discussed.

'Sorting the Wheat from the Chaff': Investigating Overload in Educational Discussion Systems

ERIC Educational Resources Information Center

Kear, Karen; Heap, N.W.

2007-01-01

This paper reports on research to investigate design features of asynchronous discussion systems for higher education. The research aims to identify features that increase the benefits of discussion systems and reduce the problems. The paper focuses on a major theme that emerged from interviews with learners and teachers: information overload.…

Dermatoglyphic peculiarities in Down's syndrome detection of mosaicism and balanced translocation carriers.

PubMed

Rodewald, A; Zang, K D; Zankl, H; Zankl, M

1981-01-01

The combination of dermatoglyphic patterns and the number and intensity of traits characteristic for Down's syndrome can be statistically expressed by the "Walker" index and the "general" index. More than 96% of a Down's syndrome series and a control series could clearly be separated by the general index. Cytogenetic and dermatoglyphic features were studied in 17 patients with mosaic trisomy 21 and their parents. In the 17 cytogenetically diagnosed patients with mosaic Down's syndrome, a highly significant correlation was observed between the percentage of trisomic cells and the presence of traits characteristic for this syndrome in the dermatoglyphic patterns. The diagnostic problems and the value of dermatoglyphic examination in cases of mosaicism, where the trisomic cell line seems to have disappeared, is discussed. The results of our study also indicate an elevated incidence of a specific dermatoglyphic pattern combination with general index values similar to Down's syndrome in one parent in nearly 20% of Down's syndrome children. The possibility of hidden mosaicism in these parents of Down's syndrome children is discussed. Furthermore, the dermatoglyphic patterns in a large kindred with an inherited 15/21 translocation (21/41 carriers of the balanced translocation; 14/41 chromosomally normal; 6/41 mongoloid members) was analyzed. The data obtained from this translocation family and especially the values obtained in the general index indicate that some dermatoglyphic stigmata are directly associated with the D/21 translocation carrier state and can therefore be used for predicting this state.

Probing features in inflaton potential and reionization history with future CMB space observations

NASA Astrophysics Data System (ADS)

Hazra, Dhiraj Kumar; Paoletti, Daniela; Ballardini, Mario; Finelli, Fabio; Shafieloo, Arman; Smoot, George F.; Starobinsky, Alexei A.

2018-02-01

We consider the prospects of probing features in the primordial power spectrum with future Cosmic Microwave Background (CMB) polarization measurements. In the scope of the inflationary scenario, such features in the spectrum can be produced by local non-smooth pieces in an inflaton potential (smooth and quasi-flat in general) which in turn may originate from fast phase transitions during inflation in other quantum fields interacting with the inflaton. They can fit some outliers in the CMB temperature power spectrum which are unaddressed within the standard inflationary ΛCDM model. We consider Wiggly Whipped Inflation (WWI) as a theoretical framework leading to improvements in the fit to the Planck 2015 temperature and polarization data in comparison with the standard inflationary models, although not at a statistically significant level. We show that some type of features in the potential within the WWI models, leading to oscillations in the primordial power spectrum that extend to intermediate and small scales can be constrained with high confidence (at 3σ or higher confidence level) by an instrument as the Cosmic ORigins Explorer (CORE). In order to investigate the possible confusion between inflationary features and footprints from the reionization era, we consider an extended reionization history with monotonic increase of free electrons with decrease in redshift. We discuss the present constraints on this model of extended reionization and future predictions with CORE. We also project, to what extent, this extended reionization can create confusion in identifying inflationary features in the data.

Generalized hypercube structures and hyperswitch communication network

NASA Technical Reports Server (NTRS)

Young, Steven D.

1992-01-01

This paper discusses an ongoing study that uses a recent development in communication control technology to implement hybrid hypercube structures. These architectures are similar to binary hypercubes, but they also provide added connectivity between the processors. This added connectivity increases communication reliability while decreasing the latency of interprocessor message passing. Because these factors directly determine the speed that can be obtained by multiprocessor systems, these architectures are attractive for applications such as remote exploration and experimentation, where high performance and ultrareliability are required. This paper describes and enumerates these architectures and discusses how they can be implemented with a modified version of the hyperswitch communication network (HCN). The HCN is analyzed because it has three attractive features that enable these architectures to be effective: speed, fault tolerance, and the ability to pass multiple messages simultaneously through the same hyperswitch controller.

Chronic anger as a precursor to adult antisocial personality features: The moderating influence of cognitive control.

PubMed

Hawes, Samuel W; Perlman, Susan B; Byrd, Amy L; Raine, Adrian; Loeber, Rolf; Pardini, Dustin A

2016-01-01

Anger is among the earliest occurring symptoms of mental health, yet we know little about its developmental course. Further, no studies have examined whether youth with persistent anger are at an increased risk of exhibiting antisocial personality features in adulthood, or how cognitive control abilities may protect these individuals from developing such maladaptive outcomes. Trajectories of anger were delineated among 503 boys using annual assessments from childhood to middle adolescence (ages ∼7-14). Associations between these trajectories and features of antisocial personality in young adulthood (age ∼28) were examined, including whether cognitive control moderates this association. Five trajectories of anger were identified (i.e., childhood-onset, childhood-limited, adolescent-onset, moderate, and low). Boys in the childhood-onset group exhibited the highest adulthood antisocial personality features (e.g., psychopathy, aggression, criminal charges). However, boys in this group were buffered from these problems if they had higher levels of cognitive control during adolescence. Findings were consistent across measures from multiple informants, replicated across distinct time periods, and remained when controlling for general intelligence and prior antisocial behavior. This is the first study to document the considerable heterogeneity in the developmental course of anger from childhood to adolescence. As hypothesized, good cognitive control abilities protected youth with persistent anger problems from developing antisocial personality features in adulthood. Clinical implications and future directions are discussed. (c) 2016 APA, all rights reserved.

Chronic Anger as a Precursor to Adult Antisocial Personality Features: The Moderating Influence of Cognitive Control

PubMed Central

Hawes, Samuel W.; Perlman, Susan B.; Byrd, Amy L.; Raine, Adrian; Loeber, Rolf; Pardini, Dustin A.

2015-01-01

Anger is among the earliest occurring symptoms of mental health, yet we know little about its developmental course. Further, no studies have examined whether youth with persistent anger are at an increased risk of exhibiting antisocial personality features in adulthood, or how cognitive control abilities may protect these individuals from developing such maladaptive outcomes. Method Trajectories of anger were delineated among 503 boys using annual assessments from childhood to middle adolescence (~ages 7–14). Associations between these trajectories and features of antisocial personality in young adulthood (~age 28) were examined, including whether cognitive control moderates this association. Results Five trajectories of anger were identified (i.e., Childhood-Onset, Childhood-Limited, Adolescent-Onset, Moderate, and Low). Boys in the Childhood-Onset group exhibited the highest adulthood antisocial personality features (e.g., psychopathy, aggression, criminal charges). However, boys in this group were buffered from these problems if they had higher levels of cognitive control during adolescence. Findings were consistent across measures from multiple informants, replicated across distinct time periods, and remained when controlling for general intelligence and prior antisocial behavior. Conclusions This is the first study to document the considerable heterogeneity in the developmental course of anger from childhood to adolescence. As hypothesized, good cognitive control abilities protected youth with persistent anger problems from developing antisocial personality features in adulthood. Clinical implications and future directions are discussed. PMID:26618654

Replicability and other features of a high-quality science: Toward a balanced and empirical approach.

PubMed

Finkel, Eli J; Eastwick, Paul W; Reis, Harry T

2017-08-01

Finkel, Eastwick, and Reis (2015; FER2015) argued that psychological science is better served by responding to apprehensions about replicability rates with contextualized solutions than with one-size-fits-all solutions. Here, we extend FER2015's analysis to suggest that much of the discussion of best research practices since 2011 has focused on a single feature of high-quality science-replicability-with insufficient sensitivity to the implications of recommended practices for other features, like discovery, internal validity, external validity, construct validity, consequentiality, and cumulativeness. Thus, although recommendations for bolstering replicability have been innovative, compelling, and abundant, it is difficult to evaluate their impact on our science as a whole, especially because many research practices that are beneficial for some features of scientific quality are harmful for others. For example, FER2015 argued that bigger samples are generally better, but also noted that very large samples ("those larger than required for effect sizes to stabilize"; p. 291) could have the downside of commandeering resources that would have been better invested in other studies. In their critique of FER2015, LeBel, Campbell, and Loving (2016) concluded, based on simulated data, that ever-larger samples are better for the efficiency of scientific discovery (i.e., that there are no tradeoffs). As demonstrated here, however, this conclusion holds only when the replicator's resources are considered in isolation. If we widen the assumptions to include the original researcher's resources as well, which is necessary if the goal is to consider resource investment for the field as a whole, the conclusion changes radically-and strongly supports a tradeoff-based analysis. In general, as psychologists seek to strengthen our science, we must complement our much-needed work on increasing replicability with careful attention to the other features of a high-quality science. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Fluorescent probe studies of polarity and solvation within room temperature ionic liquids: a review.

PubMed

Pandey, Shubha; Baker, Sheila N; Pandey, Siddharth; Baker, Gary A

2012-09-01

Ionic liquids display an array of useful and sometimes unconventional, solvent features and have attracted considerable interest in the field of green chemistry for the potential they hold to significantly reduce environmental emissions. Some of these points have a bearing on the chemical reactivity of these systems and have also generated interest in the physical and theoretical aspects of solvation in ionic liquids. This review presents an introduction to the field of ionic liquids, followed by discussion of investigations into the solvation properties of neat ionic liquids or mixed systems including ionic liquids as a major or minor component. The ionic liquid based multicomponent systems discussed are composed of other solvents, other ionic liquids, carbon dioxide, surfactants or surfactant solutions. Although we clearly focus on fluorescence spectroscopy as a tool to illuminate ionic liquid systems, the issues discussed herein are of general relevance to discussions of polarity and solvent effects in ionic liquids. Transient solvation measurements carried out by means of time-resolved fluorescence measurements are particularly powerful for their ability to parameterize the kinetics of the solvation process in ionic liquids and are discussed as well.

Generalized Feature Extraction for Wrist Pulse Analysis: From 1-D Time Series to 2-D Matrix.

PubMed

Dimin Wang; Zhang, David; Guangming Lu

2017-07-01

Traditional Chinese pulse diagnosis, known as an empirical science, depends on the subjective experience. Inconsistent diagnostic results may be obtained among different practitioners. A scientific way of studying the pulse should be to analyze the objectified wrist pulse waveforms. In recent years, many pulse acquisition platforms have been developed with the advances in sensor and computer technology. And the pulse diagnosis using pattern recognition theories is also increasingly attracting attentions. Though many literatures on pulse feature extraction have been published, they just handle the pulse signals as simple 1-D time series and ignore the information within the class. This paper presents a generalized method of pulse feature extraction, extending the feature dimension from 1-D time series to 2-D matrix. The conventional wrist pulse features correspond to a particular case of the generalized models. The proposed method is validated through pattern classification on actual pulse records. Both quantitative and qualitative results relative to the 1-D pulse features are given through diabetes diagnosis. The experimental results show that the generalized 2-D matrix feature is effective in extracting both the periodic and nonperiodic information. And it is practical for wrist pulse analysis.

Genetic (idiopathic) epilepsy with photosensitive seizures includes features of both focal and generalized seizures.

PubMed

Xue, Jiao; Gong, Pan; Yang, Haipo; Liu, Xiaoyan; Jiang, Yuwu; Zhang, Yuehua; Yang, Zhixian

2018-04-19

Clinically, some patients having genetic (idiopathic) epilepsy with photosensitive seizures were difficult to be diagnosed. We aimed to discuss whether the genetic (idiopathic) epilepsy with photosensitive seizures is a focal entity, a generalized entity or a continuum. Twenty-two patients with idiopathic epilepsies and photoconvulsive response (PCR) were retrospectively recruited. In the medical records, the seizure types included "generalized tonic-clonic seizures (GTCS)" in 15, "partial secondarily GTCS (PGTCS)" in 3, partial seizures (PS) in 3, myoclonic seizures in 2, eyelid myoclonus in one, and only febrile seizures in one. Seizure types of PCR included GTCS (1/22), PGTCS (6/22), PS (9/22), electrical seizures (ES) (3/22) and GTCS/PGTCS (3/22). Combined the medical history with PCR results, they were diagnosed as: idiopathic (photosensitive) occipital lobe epilepsy (I(P)OE) in 12, genetic (idiopathic) generalized epilepsy (GGE) in one, GGE/I(P)OE in 5, pure photosensitive seizure in one, and epilepsy with undetermined generalized or focal seizure in 3. So, the dichotomy between generalized and focal seizures might have been out of date regarding to pathophysiological advances in epileptology. To some extent, it would be better to recognize the idiopathic epilepsy with photosensitive seizures as a continuum between focal and generalized seizures.

A haptic model of vibration modes in spherical geometry and its application in atomic physics, nuclear physics and beyond

NASA Astrophysics Data System (ADS)

Ubben, Malte; Heusler, Stefan

2018-07-01

Vibration modes in spherical geometry can be classified based on the number and position of nodal planes. However, the geometry of these planes is non-trivial and cannot be easily displayed in two dimensions. We present 3D-printed models of those vibration modes, enabling a haptic approach for understanding essential features of bound states in quantum physics and beyond. In particular, when applied to atomic physics, atomic orbitals are obtained in a natural manner. Applied to nuclear physics, the same patterns of vibration modes emerge as cornerstone for the nuclear shell model. These applications of the very same model in a range of more than 5 orders of magnitude in length scales leads to a general discussion of the applicability and limits of validity of physical models in general.

Mouse models for the study of colon carcinogenesis

PubMed Central

Rosenberg, Daniel W.; Giardina, Charles; Tanaka, Takuji

2009-01-01

The study of experimental colon carcinogenesis in rodents has a long history, dating back almost 80 years. There are many advantages to studying the pathogenesis of carcinogen-induced colon cancer in mouse models, including rapid and reproducible tumor induction and the recapitulation of the adenoma–carcinoma sequence that occurs in humans. The availability of recombinant inbred mouse panels and the existence of transgenic, knock-out and knock-in genetic models further increase the value of these studies. In this review, we discuss the general mechanisms of tumor initiation elicited by commonly used chemical carcinogens and how genetic background influences the extent of disease. We will also describe the general features of lesions formed in response to carcinogen treatment, including the underlying molecular aberrations and how these changes may relate to the pathogenesis of human colorectal cancer. PMID:19037092

Molecular brain imaging in the multimodality era

PubMed Central

Price, Julie C

2012-01-01

Multimodality molecular brain imaging encompasses in vivo visualization, evaluation, and measurement of cellular/molecular processes. Instrumentation and software developments over the past 30 years have fueled advancements in multimodality imaging platforms that enable acquisition of multiple complementary imaging outcomes by either combined sequential or simultaneous acquisition. This article provides a general overview of multimodality neuroimaging in the context of positron emission tomography as a molecular imaging tool and magnetic resonance imaging as a structural and functional imaging tool. Several image examples are provided and general challenges are discussed to exemplify complementary features of the modalities, as well as important strengths and weaknesses of combined assessments. Alzheimer's disease is highlighted, as this clinical area has been strongly impacted by multimodality neuroimaging findings that have improved understanding of the natural history of disease progression, early disease detection, and informed therapy evaluation. PMID:22434068

Evaluation of the constant pressure panel method (CPM) for unsteady air loads prediction

NASA Technical Reports Server (NTRS)

Appa, Kari; Smith, Michael J. C.

1988-01-01

This paper evaluates the capability of the constant pressure panel method (CPM) code to predict unsteady aerodynamic pressures, lift and moment distributions, and generalized forces for general wing-body configurations in supersonic flow. Stability derivatives are computed and correlated for the X-29 and an Oblique Wing Research Aircraft, and a flutter analysis is carried out for a wing wind tunnel test example. Most results are shown to correlate well with test or published data. Although the emphasis of this paper is on evaluation, an improvement in the CPM code's handling of intersecting lifting surfaces is briefly discussed. An attractive feature of the CPM code is that it shares the basic data requirements and computational arrangements of the doublet lattice method. A unified code to predict unsteady subsonic or supersonic airloads is therefore possible.

Innovation: an emerging focus from cells to societies.

PubMed

Hochberg, Michael E; Marquet, Pablo A; Boyd, Robert; Wagner, Andreas

2017-12-05

Innovations are generally unexpected, often spectacular changes in phenotypes and ecological functions. The contributions to this theme issue are the latest conceptual, theoretical and experimental developments, addressing how ecology, environment, ontogeny and evolution are central to understanding the complexity of the processes underlying innovations. Here, we set the stage by introducing and defining key terms relating to innovation and discuss their relevance to biological, cultural and technological change. Discovering how the generation and transmission of novel biological information, environmental interactions and selective evolutionary processes contribute to innovation as an ecosystem will shed light on how the dominant features across life come to be, generalize to social, cultural and technological evolution, and have applications in the health sciences and sustainability.This article is part of the theme issue 'Process and pattern in innovations from cells to societies'. © 2017 The Author(s).

Innovation: an emerging focus from cells to societies

PubMed Central

Boyd, Robert

2017-01-01

Innovations are generally unexpected, often spectacular changes in phenotypes and ecological functions. The contributions to this theme issue are the latest conceptual, theoretical and experimental developments, addressing how ecology, environment, ontogeny and evolution are central to understanding the complexity of the processes underlying innovations. Here, we set the stage by introducing and defining key terms relating to innovation and discuss their relevance to biological, cultural and technological change. Discovering how the generation and transmission of novel biological information, environmental interactions and selective evolutionary processes contribute to innovation as an ecosystem will shed light on how the dominant features across life come to be, generalize to social, cultural and technological evolution, and have applications in the health sciences and sustainability. This article is part of the theme issue ‘Process and pattern in innovations from cells to societies’. PMID:29061887

Analysis of aircraft spectrometer data with logarithmic residuals

NASA Technical Reports Server (NTRS)

Green, A. A.; Craig, M. D.

1985-01-01

Spectra from airborne systems must be analyzed in terms of their mineral-related absorption features. Methods for removing backgrounds and extracting these features one at a time from reflectance spectra are discussed. Methods for converting radiance spectra into a form similar to reflectance spectra so that the feature extraction procedures can be implemented on aircraft spectrometer data are also discussed.

The role of semantic complexity in treatment of naming deficits: training semantic categories in fluent aphasia by controlling exemplar typicality.

PubMed

Kiran, Swathi; Thompson, Cynthia K

2003-06-01

The effect of typicality of category exemplars on naming was investigated using a single subject experimental design across participants and behaviors in 4 patients with fluent aphasia. Participants received a semantic feature treatment to improve naming of either typical or atypical items within semantic categories, while generalization was tested to untrained items of the category. The order of typicality and category trained was counterbalanced across participants. Results indicated that patients trained on naming of atypical exemplars demonstrated generalization to naming of intermediate and typical items. However, patients trained on typical items demonstrated no generalized naming effect to intermediate or atypical examples. Furthermore, analysis of errors indicated an evolution of errors throughout training, from those with no apparent relationship to the target to primarily semantic and phonemic paraphasias. Performance on standardized language tests also showed changes as a function of treatment. Theoretical and clinical implications regarding the impact of considering semantic complexity on rehabilitation of naming deficits in aphasia are discussed.

The role of semantic complexity in treatment of naming deficits: training semantic categories in fluent aphasia by controlling exemplar typicality.

PubMed

Kiran, Swathi; Thompson, Cynthia K

2003-08-01

The effect of typicality of category exemplars on naming was investigated using a single subject experimental design across participants and behaviors in 4 patients with fluent aphasia. Participants received a semantic feature treatment to improve naming of either typical or atypical items within semantic categories, while generalization was tested to untrained items of the category. The order of typicality and category trained was counterbalanced across participants. Results indicated that patients trained on naming of atypical exemplars demonstrated generalization to naming of intermediate and typical items. However, patients trained on typical items demonstrated no generalized naming effect to intermediate or atypical examples. Furthermore, analysis of errors indicated an evolution of errors throughout training, from those with no apparent relationship to the target to primarily semantic and phonemic paraphasias. Performance on standardized language tests also showed changes as a function of treatment. Theoretical and clinical implications regarding the impact of considering semantic complexity on rehabilitation of naming deficits in aphasia are discussed.

On gravitational waves in Born-Infeld inspired non-singular cosmologies

NASA Astrophysics Data System (ADS)

Beltrán Jiménez, Jose; Heisenberg, Lavinia; Olmo, Gonzalo J.; Rubiera-Garcia, Diego

2017-10-01

We study the evolution of gravitational waves for non-singular cosmological solutions within the framework of Born-Infeld inspired gravity theories, with special emphasis on the Eddington-inspired Born-Infeld theory. We review the existence of two types of non-singular cosmologies, namely bouncing and asymptotically Minkowski solutions, from a perspective that makes their features more apparent. We study in detail the propagation of gravitational waves near these non-singular solutions and carefully discuss the origin and severity of the instabilities and strong coupling problems that appear. We also investigate the role of the adiabatic sound speed of the matter sector in the regularisation of the gravitational waves evolution. We extend our analysis to more general Born-Infeld inspired theories where analogous solutions are found. As a general conclusion, we obtain that the bouncing solutions are generally more prone to instabilities, while the asymptotically Minkowski solutions can be rendered stable, making them appealing models for the early universe.

Adolescents' sexual scripts: schematic representations of consensual and nonconsensual heterosexual interactions.

PubMed

Krahé, Barbara; Bieneck, Steffen; Scheinberger-Olwig, Renate

2007-11-01

The characteristic features of adolescents' sexual scripts were explored in 400 tenth and eleventh graders from Berlin, Germany. Participants rated the prototypical elements of three scripts for heterosexual interactions: (1) the prototypical script for the first consensual sexual intercourse with a new partner as pertaining to adolescents in general (general script); (2) the prototypical script for the first consensual sexual intercourse with a new partner as pertaining to themselves personally (individual script); and (3) the script for a nonconsensual sexual intercourse (rape script). Compared with the general script for the age group as a whole, the individual script contained fewer risk elements related to sexual aggression and portrayed more positive consequences of the sexual interaction. Few gender differences were found, and coital experience did not affect sexual scripts. The rape script was found to be close to the "real rape stereotype." The findings are discussed with respect to the role of sexual scripts as guidelines for behavior, particularly in terms of their significance for the prediction of sexual aggression.

Computation of three-dimensional nozzle-exhaust flow fields with the GIM code

NASA Technical Reports Server (NTRS)

Spradley, L. W.; Anderson, P. G.

1978-01-01

A methodology is introduced for constructing numerical analogs of the partial differential equations of continuum mechanics. A general formulation is provided which permits classical finite element and many of the finite difference methods to be derived directly. The approach, termed the General Interpolants Method (GIM), can combined the best features of finite element and finite difference methods. A quasi-variational procedure is used to formulate the element equations, to introduce boundary conditions into the method and to provide a natural assembly sequence. A derivation is given in terms of general interpolation functions from this procedure. Example computations for transonic and supersonic flows in two and three dimensions are given to illustrate the utility of GIM. A three-dimensional nozzle-exhaust flow field is solved including interaction with the freestream and a coupled treatment of the shear layer. Potential applications of the GIM code to a variety of computational fluid dynamics problems is then discussed in terms of existing capability or by extension of the methodology.

On gravitational waves in Born-Infeld inspired non-singular cosmologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiménez, Jose Beltrán; Heisenberg, Lavinia; Olmo, Gonzalo J.

We study the evolution of gravitational waves for non-singular cosmological solutions within the framework of Born-Infeld inspired gravity theories, with special emphasis on the Eddington-inspired Born-Infeld theory. We review the existence of two types of non-singular cosmologies, namely bouncing and asymptotically Minkowski solutions, from a perspective that makes their features more apparent. We study in detail the propagation of gravitational waves near these non-singular solutions and carefully discuss the origin and severity of the instabilities and strong coupling problems that appear. We also investigate the role of the adiabatic sound speed of the matter sector in the regularisation of themore » gravitational waves evolution. We extend our analysis to more general Born-Infeld inspired theories where analogous solutions are found. As a general conclusion, we obtain that the bouncing solutions are generally more prone to instabilities, while the asymptotically Minkowski solutions can be rendered stable, making them appealing models for the early universe.« less

Feature Analysis of Generalized Data Base Management Systems.

ERIC Educational Resources Information Center

Conference on Data Systems Languages, Monroeville, PA. Systems Committee.

A more complete definition of the features offered in present day generalized data base management systems is provided by this second technical report of the CODASYL Systems Committee. In a tutorial format, each feature description is followed by either narrative information covering ten systems or by a table for all systems. The ten systems…

Surprise! Infants consider possible bases of generalization for a single input example.

PubMed

Gerken, LouAnn; Dawson, Colin; Chatila, Razanne; Tenenbaum, Josh

2015-01-01

Infants have been shown to generalize from a small number of input examples. However, existing studies allow two possible means of generalization. One is via a process of noting similarities shared by several examples. Alternatively, generalization may reflect an implicit desire to explain the input. The latter view suggests that generalization might occur when even a single input example is surprising, given the learner's current model of the domain. To test the possibility that infants are able to generalize based on a single example, we familiarized 9-month-olds with a single three-syllable input example that contained either one surprising feature (syllable repetition, Experiment 1) or two features (repetition and a rare syllable, Experiment 2). In both experiments, infants generalized only to new strings that maintained all of the surprising features from familiarization. This research suggests that surprise can promote very rapid generalization. © 2014 John Wiley & Sons Ltd.

A novel feature extraction approach for microarray data based on multi-algorithm fusion

PubMed Central

Jiang, Zhu; Xu, Rong

2015-01-01

Feature extraction is one of the most important and effective method to reduce dimension in data mining, with emerging of high dimensional data such as microarray gene expression data. Feature extraction for gene selection, mainly serves two purposes. One is to identify certain disease-related genes. The other is to find a compact set of discriminative genes to build a pattern classifier with reduced complexity and improved generalization capabilities. Depending on the purpose of gene selection, two types of feature extraction algorithms including ranking-based feature extraction and set-based feature extraction are employed in microarray gene expression data analysis. In ranking-based feature extraction, features are evaluated on an individual basis, without considering inter-relationship between features in general, while set-based feature extraction evaluates features based on their role in a feature set by taking into account dependency between features. Just as learning methods, feature extraction has a problem in its generalization ability, which is robustness. However, the issue of robustness is often overlooked in feature extraction. In order to improve the accuracy and robustness of feature extraction for microarray data, a novel approach based on multi-algorithm fusion is proposed. By fusing different types of feature extraction algorithms to select the feature from the samples set, the proposed approach is able to improve feature extraction performance. The new approach is tested against gene expression dataset including Colon cancer data, CNS data, DLBCL data, and Leukemia data. The testing results show that the performance of this algorithm is better than existing solutions. PMID:25780277

A novel feature extraction approach for microarray data based on multi-algorithm fusion.

PubMed

Jiang, Zhu; Xu, Rong

2015-01-01

Feature extraction is one of the most important and effective method to reduce dimension in data mining, with emerging of high dimensional data such as microarray gene expression data. Feature extraction for gene selection, mainly serves two purposes. One is to identify certain disease-related genes. The other is to find a compact set of discriminative genes to build a pattern classifier with reduced complexity and improved generalization capabilities. Depending on the purpose of gene selection, two types of feature extraction algorithms including ranking-based feature extraction and set-based feature extraction are employed in microarray gene expression data analysis. In ranking-based feature extraction, features are evaluated on an individual basis, without considering inter-relationship between features in general, while set-based feature extraction evaluates features based on their role in a feature set by taking into account dependency between features. Just as learning methods, feature extraction has a problem in its generalization ability, which is robustness. However, the issue of robustness is often overlooked in feature extraction. In order to improve the accuracy and robustness of feature extraction for microarray data, a novel approach based on multi-algorithm fusion is proposed. By fusing different types of feature extraction algorithms to select the feature from the samples set, the proposed approach is able to improve feature extraction performance. The new approach is tested against gene expression dataset including Colon cancer data, CNS data, DLBCL data, and Leukemia data. The testing results show that the performance of this algorithm is better than existing solutions.

Pathological narcissism and acute anxiety symptoms after trauma: a study of Israeli civilians exposed to war.

PubMed

Besser, Avi; Zeigler-Hill, Virgil; Pincus, Aaron L; Neria, Yuval

2013-01-01

Diathesis-stress models of posttraumatic stress disorder (PTSD) hypothesize that exposure to trauma may interact with individual differences in the development of PTSD. Previous studies have not assessed immediate responses to a proximate stressor, but the current "natural laboratory" study was designed to empirically test the role that individual differences in pathological narcissism may play in the development of acute anxiety symptoms among civilians facing rocket and missile fire. We assessed demographic features, trauma exposure severity, narcissistic personality features, and acute anxiety symptoms (PTSD and General Anxiety Disorder [GAD]) among 342 Israeli female adults during the November 2012 eruption of violence in the Middle East. Results demonstrate an association between exposure severity and acute anxiety symptoms (both PTSD and GAD) for individuals with high levels of pathological narcissism but not for those with low levels of pathological narcissism. These results suggest that individuals with narcissistic personality features are at high risk for the development of acute anxiety symptoms following exposure to uncontrollable and life-threatening mass trauma. The findings underscore the role of intra-personal resources in the immediate psychological aftermath of war by highlighting the increased risk associated with narcissistic personality features. Theoretical and clinical implications of the findings are discussed.

Statistical molecular design of balanced compound libraries for QSAR modeling.

PubMed

Linusson, A; Elofsson, M; Andersson, I E; Dahlgren, M K

2010-01-01

A fundamental step in preclinical drug development is the computation of quantitative structure-activity relationship (QSAR) models, i.e. models that link chemical features of compounds with activities towards a target macromolecule associated with the initiation or progression of a disease. QSAR models are computed by combining information on the physicochemical and structural features of a library of congeneric compounds, typically assembled from two or more building blocks, and biological data from one or more in vitro assays. Since the models provide information on features affecting the compounds' biological activity they can be used as guides for further optimization. However, in order for a QSAR model to be relevant to the targeted disease, and drug development in general, the compound library used must contain molecules with balanced variation of the features spanning the chemical space believed to be important for interaction with the biological target. In addition, the assays used must be robust and deliver high quality data that are directly related to the function of the biological target and the associated disease state. In this review, we discuss and exemplify the concept of statistical molecular design (SMD) in the selection of building blocks and final synthetic targets (i.e. compounds to synthesize) to generate information-rich, balanced libraries for biological testing and computation of QSAR models.

Understanding adolescent personality pathology from growth trajectories of childhood oddity.

PubMed

De Clercq, Barbara; Verbeke, Lize; De Caluwé, Elien; Vercruysse, Tom; Hofmans, Joeri

2017-10-01

Research on developmental trajectories of early maladaptive features for understanding later personality disorders (PDs) is increasingly recognized as an important study area. The course of early odd features is highly relevant in this regard, as only a few researchers have addressed childhood oddity in the context of emerging PDs. Using latent growth modeling, the current study explores growth parameters of odd features in a mixed sample of Flemish community and referred children (N = 485) across three measurement waves with 1-year time intervals. Personality pathology was assessed at a fourth assessment point in adolescence. Beyond a general declining trend in oddity characteristics, the results demonstrated that both an early onset and an increasing trend of oddity-related characteristics over time are independent predictors of adolescent PDs. Childhood oddity tends to be the most manifest precursor for PDs with a core oddity feature (i.e., the schizotypal and borderline PD), but also appears to predict most of the other DSM-5 PDs. Results are discussed from an overarching developmental framework on PDs (Cicchetti, 2014), specifically focusing on the principle of multifinality. From a clinical perspective, the significance of increasing or steady-high childhood oddity trajectories for adolescent PDs highlights the relevance of systematic screening processes across time.

Evaluation of natural language processing systems: Issues and approaches

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guida, G.; Mauri, G.

This paper encompasses two main topics: a broad and general analysis of the issue of performance evaluation of NLP systems and a report on a specific approach developed by the authors and experimented on a sample test case. More precisely, it first presents a brief survey of the major works in the area of NLP systems evaluation. Then, after introducing the notion of the life cycle of an NLP system, it focuses on the concept of performance evaluation and analyzes the scope and the major problems of the investigation. The tools generally used within computer science to assess the qualitymore » of a software system are briefly reviewed, and their applicability to the task of evaluation of NLP systems is discussed. Particular attention is devoted to the concepts of efficiency, correctness, reliability, and adequacy, and how all of them basically fail in capturing the peculiar features of performance evaluation of an NLP system is discussed. Two main approaches to performance evaluation are later introduced; namely, black-box- and model-based, and their most important characteristics are presented. Finally, a specific model for performance evaluation proposed by the authors is illustrated, and the results of an experiment with a sample application are reported. The paper concludes with a discussion on research perspective, open problems, and importance of performance evaluation to industrial applications.« less

Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C–H activation

DOE PAGES

Huang, Xiongyi; Groves, John T.

2016-12-01

Since our initial report in 1976, the oxygen rebound mechanism has become the consensus mechanistic feature for an expanding variety of enzymatic C–H functionalization reactions and small molecule biomimetic catalysts. For both the biotransformations and models, an initial hydrogen atom abstraction from the substrate (R–H) by high-valent iron-oxo species (Fe n=O) generates a substrate radical and a reduced iron hydroxide, [Fe n-1–OH ·R]. This caged radical pair then evolves on a complicated energy landscape through a number of reaction pathways, such as oxygen rebound to form R–OH, rebound to a non-oxygen atom affording R–X, electron transfer of the incipient radicalmore » to yield a carbocation, R +, desaturation to form olefins, and radical cage escape. These various flavors of the rebound process, often in competition with each other, give rise to the wide range of C–H functionalization reactions performed by iron-containing oxygenases. In this review, we first recount the history of radical rebound mechanisms, their general features, and key intermediates involved. We will discuss in detail the factors that affect the behavior of the initial caged radical pair and the lifetimes of the incipient substrate radicals. Several representative examples of enzymatic C–H transformations are selected to illustrate how the behaviors of the radical pair [Fe n-1–OH ·R] determine the eventual reaction outcome. Finally, we discuss the powerful potential of “radical rebound” processes as a general paradigm for developing novel C–H functionalization reactions with synthetic, biomimetic catalysts. We envision that new chemistry will continue to arise by bridging enzymatic “radical rebound” with synthetic organic chemistry.« less

Longitudinal Validation of General and Specific Structural Features of Personality Pathology

PubMed Central

Wright, Aidan G.C.; Hopwood, Christopher J.; Skodol, Andrew E.; Morey, Leslie C.

2016-01-01

Theorists have long argued that personality disorder (PD) is best understood in terms of general impairments shared across the disorders as well as more specific instantiations of pathology. A model based on this theoretical structure was proposed as part of the DSM-5 revision process. However, only recently has this structure been subjected to formal quantitative evaluation, with little in the way of validation efforts via external correlates or prospective longitudinal prediction. We used the Collaborative Longitudinal Study of Personality Disorders dataset to: (1) estimate structural models that parse general from specific variance in personality disorder features, (2) examine patterns of growth in general and specific features over the course of 10 years, and (3) establish concurrent and dynamic longitudinal associations in PD features and a host of external validators including basic personality traits and psychosocial functioning scales. We found that general PD exhibited much lower absolute stability and was most strongly related to broad markers of psychosocial functioning, concurrently and longitudinally, whereas specific features had much higher mean stability and exhibited more circumscribed associations with functioning. However, both general and specific factors showed recognizable associations with normative and pathological traits. These results can inform efforts to refine the conceptualization and diagnosis of personality pathology. PMID:27819472

Understanding Clicker Discussions: Student Reasoning and the Impact of Instructional Cues

PubMed Central

Knight, Jennifer K.; Wise, Sarah B.; Southard, Katelyn M.

2013-01-01

Previous research has shown that undergraduate science students learn from peer discussions of in-class clicker questions. However, the features that characterize such discussions are largely unknown, as are the instructional factors that may lead students into productive discussions. To explore these questions, we recorded and transcribed 83 discussions among groups of students discussing 34 different clicker questions in an upper-level developmental biology class. Discussion transcripts were analyzed for features such as making claims, questioning, and explaining reasoning. In addition, transcripts were categorized by the quality of reasoning students used and for performance features, such as percent correct on initial vote, percent correct on revote, and normalized learning change. We found that the majority of student discussions included exchanges of reasoning that used evidence and that many such exchanges resulted in students achieving the correct answer. Students also had discussions in which ideas were exchanged, but the correct answer not achieved. Importantly, instructor prompts that asked students to use reasoning resulted in significantly more discussions containing reasoning connected to evidence than without such prompts. Overall, these results suggest that these upper-level biology students readily employ reasoning in their discussions and are positively influenced by instructor cues. PMID:24297291

Video game characteristics, happiness and flow as predictors of addiction among video game players: A pilot study.

PubMed

Hull, Damien C; Williams, Glenn A; Griffiths, Mark D

2013-09-01

Video games provide opportunities for positive psychological experiences such as flow-like phenomena during play and general happiness that could be associated with gaming achievements. However, research has shown that specific features of game play may be associated with problematic behaviour associated with addiction-like experiences. The study was aimed at analysing whether certain structural characteristics of video games, flow, and global happiness could be predictive of video game addiction. A total of 110 video game players were surveyed about a game they had recently played by using a 24-item checklist of structural characteristics, an adapted Flow State Scale, the Oxford Happiness Questionnaire, and the Game Addiction Scale. The study revealed decreases in general happiness had the strongest role in predicting increases in gaming addiction. One of the nine factors of the flow experience was a significant predictor of gaming addiction - perceptions of time being altered during play. The structural characteristic that significantly predicted addiction was its social element with increased sociability being associated with higher levels of addictive-like experiences. Overall, the structural characteristics of video games, elements of the flow experience, and general happiness accounted for 49.2% of the total variance in Game Addiction Scale levels. Implications for interventions are discussed, particularly with regard to making players more aware of time passing and in capitalising on benefits of social features of video game play to guard against addictive-like tendencies among video game players.

Video game characteristics, happiness and flow as predictors of addiction among video game players: A pilot study

PubMed Central

Hull, Damien C.; Williams, Glenn A.; Griffiths, Mark D.

2013-01-01

Aims: Video games provide opportunities for positive psychological experiences such as flow-like phenomena during play and general happiness that could be associated with gaming achievements. However, research has shown that specific features of game play may be associated with problematic behaviour associated with addiction-like experiences. The study was aimed at analysing whether certain structural characteristics of video games, flow, and global happiness could be predictive of video game addiction. Method: A total of 110 video game players were surveyed about a game they had recently played by using a 24-item checklist of structural characteristics, an adapted Flow State Scale, the Oxford Happiness Questionnaire, and the Game Addiction Scale. Results: The study revealed decreases in general happiness had the strongest role in predicting increases in gaming addiction. One of the nine factors of the flow experience was a significant predictor of gaming addiction – perceptions of time being altered during play. The structural characteristic that significantly predicted addiction was its social element with increased sociability being associated with higher levels of addictive-like experiences. Overall, the structural characteristics of video games, elements of the flow experience, and general happiness accounted for 49.2% of the total variance in Game Addiction Scale levels. Conclusions: Implications for interventions are discussed, particularly with regard to making players more aware of time passing and in capitalising on benefits of social features of video game play to guard against addictive-like tendencies among video game players. PMID:25215196

The significance of the Skylab altimeter experiment results and potential applications. [measurement of sea surface topography

NASA Technical Reports Server (NTRS)

Mourad, A. G.; Gopalapillai, S.; Kuhner, M.

1975-01-01

The Skylab Altimeter Experiment has proven the capability of the altimeter for measurement of sea surface topography. The geometric determination of the geoid/mean sea level from satellite altimetry is a new approach having significant applications in many disciplines including geodesy and oceanography. A Generalized Least Squares Collocation Technique was developed for determination of the geoid from altimetry data. The technique solves for the altimetry geoid and determines one bias term for the combined effect of sea state, orbit, tides, geoid, and instrument error using sparse ground truth data. The influence of errors in orbit and a priori geoid values are discussed. Although the Skylab altimeter instrument accuracy is about + or - 1 m, significant results were obtained in identification of large geoidal features such as over the Puerto Rico trench. Comparison of the results of several passes shows that good agreement exists between the general slopes of the altimeter geoid and the ground truth, and that the altimeter appears to be capable of providing more details than are now available with best known geoids. The altimetry geoidal profiles show excellent correlations with bathymetry and gravity. Potential applications of altimetry results to geodesy, oceanography, and geophysics are discussed.

To appreciate variation between scientists: A perspective for seeing science's vitality

NASA Astrophysics Data System (ADS)

Wong, E. David

2002-05-01

At the heart of theoretical and practical ideas about science education is an image of scientific work. This image draws attention to particular features of scientific work, which then guides scholarship and pedagogy in science education. In the field of science education, much discussion in this vein focuses on the question, What is the nature of science? Most images of science found in education, psychology, and philosophy emerge from conceptual and methodological perspectives that emphasize norms, conventions, and broad trends. Some groups are motivated to distinguish science from other activities while some groups work in the opposite direction and blur the lines between science and others ways of knowing. Underlying both perspectives is an implicit focus on general qualities common to groups or subgroups (e.g. believing that ideas are subject to change, explanations demand evidence, science is a complex social activities, etc.). I propose that the vital qualities of science are best illuminated by just the opposite process: by appreciating the uncommon, rather than common, features. By attending to individual variation, we are more likely to understand what makes science a creative, motivating, and deeply personal enterprise. In addition, appreciating these variations reveals judgment, creativity, adaptation - the hallmark of scientific work. Implications of this perspective for science education are discussed.

Some Features of the Variation of the Magnetic Field Characteristics in the Umbra of Sunspots During Flares and Coronal Mass Ejections

NASA Astrophysics Data System (ADS)

Zagainova, Yu. S.; Fainshtein, V. G.; Rudenko, G. V.; Obridko, V. N.

2017-12-01

The observed variations of the magnetic properties of sunspots during eruptive events (solar flares and coronal mass ejections (CMEs)) are discussed. Variations of the magnetic field characteristics in the umbra of the sunspots of active regions (ARs) recorded during eruptive events on August 2, 2011, March 9, 2012, April 11, 2013, January 7, 2014, and June 18, 2015, are studied. The behavior of the maximum of the total field strength B max, the minimum inclination angle of the field lines to the radial direction from the center of the Sun αmin (i.e., the inclination angle of the axis of the magnetic tube from the sunspot umbra), and values of these parameters B mean and αmean mean within the umbra are analyzed. The main results of our investigation are discussed by the example of the event on August 2, 2011, but, in general, the observed features of the variation of magnetic field properties in AR sunspots are similar for all of the considered eruptive events. It is shown that, after the flare onset in six AR sunspots on August 2, 2011, the behavior of the specified magnetic field parameters changes in comparison with that observed before the flare onset.

Hidden Markov Model and Support Vector Machine based decoding of finger movements using Electrocorticography

PubMed Central

Wissel, Tobias; Pfeiffer, Tim; Frysch, Robert; Knight, Robert T.; Chang, Edward F.; Hinrichs, Hermann; Rieger, Jochem W.; Rose, Georg

2013-01-01

Objective Support Vector Machines (SVM) have developed into a gold standard for accurate classification in Brain-Computer-Interfaces (BCI). The choice of the most appropriate classifier for a particular application depends on several characteristics in addition to decoding accuracy. Here we investigate the implementation of Hidden Markov Models (HMM)for online BCIs and discuss strategies to improve their performance. Approach We compare the SVM, serving as a reference, and HMMs for classifying discrete finger movements obtained from the Electrocorticograms of four subjects doing a finger tapping experiment. The classifier decisions are based on a subset of low-frequency time domain and high gamma oscillation features. Main results We show that decoding optimization between the two approaches is due to the way features are extracted and selected and less dependent on the classifier. An additional gain in HMM performance of up to 6% was obtained by introducing model constraints. Comparable accuracies of up to 90% were achieved with both SVM and HMM with the high gamma cortical response providing the most important decoding information for both techniques. Significance We discuss technical HMM characteristics and adaptations in the context of the presented data as well as for general BCI applications. Our findings suggest that HMMs and their characteristics are promising for efficient online brain-computer interfaces. PMID:24045504

Some Questions about Feature Re-Assembly

ERIC Educational Resources Information Center

White, Lydia

2009-01-01

In this commentary, differences between feature re-assembly and feature selection are discussed. Lardiere's proposals are compared to existing approaches to grammatical features in second language (L2) acquisition. Questions are raised about the predictive power of the feature re-assembly approach. (Contains 1 footnote.)

Unravelling the pathophysiology of delirium: a focus on the role of aberrant stress responses

PubMed Central

MacLullich, Alasdair MJ; Ferguson, Karen J; Miller, Thomas; de Rooij, Sophia EJA; Cunningham, Colm

2015-01-01

Delirium is a common and serious acute neuropsychiatric syndrome with core features of inattention and cognitive impairment, and associated features including changes in arousal, altered sleep-wake cycle, and other changes in mental status. The main risk factors are old age, cognitive impairment, and other comorbidities. Though delirium has consistent core clinical features, it has a very wide range of precipitating factors, including acute illness, surgery, trauma, and drugs. The molecular mechanisms by which these precipitating factors lead to delirium are largely obscure. In this article we attempt to narrow down some specific causal pathways. We propose a basic classification for the aetiological factors: (a) direct brain insults, and (b) aberrant stress responses. Direct brain insults are largely indiscriminate and include general and regional energy deprivation (eg. hypoxia, hypoglycaemia, stroke), metabolic abnormalities (eg. hyponatraemia, hypercalcaemia), and the effects of drugs. Aberrant stress responses are conceptually and mechanistically distinct in that they constitute adverse effects of stress-response pathways which, in health, are adaptive. Ageing and central nervous system disease, two major predisposing factors for delirium, are associated with alterations in the magnitude or duration of stress and sickness behaviour responses, and increased vulnerability to the effects of these responses. We discuss in detail two stress response systems that are likely to be involved in the pathophysiology of delirium: inflammation and the sickness behaviour response, and activity of the limbic-hypothalamic-pituitary-adrenal axis. We conclude by discussing the implications for future research and the development of new therapies for delirium. PMID:18707945

Reciprocal peer review for quality improvement: an ethnographic case study of the Improving Lung Cancer Outcomes Project.

PubMed

Aveling, Emma-Louise; Martin, Graham; Jiménez García, Senai; Martin, Lisa; Herbert, Georgia; Armstrong, Natalie; Dixon-Woods, Mary; Woolhouse, Ian

2012-12-01

Peer review offers a promising way of promoting improvement in health systems, but the optimal model is not yet clear. We aimed to describe a specific peer review model-reciprocal peer-to-peer review (RP2PR)-to identify the features that appeared to support optimal functioning. We conducted an ethnographic study involving observations, interviews and documentary analysis of the Improving Lung Cancer Outcomes Project, which involved 30 paired multidisciplinary lung cancer teams participating in facilitated reciprocal site visits. Analysis was based on the constant comparative method. Fundamental features of the model include multidisciplinary participation, a focus on discussion and observation of teams in action, rather than paperwork; facilitated reflection and discussion on data and observations; support to develop focused improvement plans. Five key features were identified as important in optimising this model: peers and pairing methods; minimising logistic burden; structure of visits; independent facilitation; and credibility of the process. Facilitated RP2PR was generally a positive experience for participants, but implementing improvement plans was challenging and required substantial support. RP2PR appears to be optimised when it is well organised; a safe environment for learning is created; credibility is maximised; implementation and impact are supported. RP2PR is seen as credible and legitimate by lung cancer teams and can act as a powerful stimulus to produce focused quality improvement plans and to support implementation. Our findings have identified how RP2PR functioned and may be optimised to provide a constructive, open space for identifying opportunities for improvement and solutions.

Sepsis in Obstetrics: Clinical Features and Early Warning Tools.

PubMed

Parfitt, Sheryl E; Bogat, Mary L; Hering, Sandra L; Ottley, Charlotte; Roth, Cheryl

Morbidity and mortality associated with sepsis has gained widespread attention on a local, state, and national level, yet, it remains a complicated disorder that can be difficult to identify in a timely manner. Sepsis in obstetric patients further complicates the diagnosis as alterations in physiology related to pregnancy can mask sepsis indicators normally seen in the general population. If early signs of sepsis go unrecognized, septic shock can develop, leading to organ dysfunction and potential death. Maternal early warning tools have been designed to assist clinicians in recognizing early indications of illness. Through use of clinical pathway-specific tools, disease processes may be detected early, subsequently benefitting patients with aggressive treatment management and intervention.This article is the second in a series of three that discuss the importance of sepsis and septic shock in pregnancy. Risk factors, causes of sepsis, signs and symptoms, and maternal early warning tools are discussed.

Description of bipolar charge transport in polyethylene using a fluid model with a constant mobility: model prediction

NASA Astrophysics Data System (ADS)

LeRoy, S.; Segur, P.; Teyssedre, G.; Laurent, C.

2004-01-01

We present a conduction model aimed at describing bipolar transport and space charge phenomena in low density polyethylene under dc stress. In the first part we recall the basic requirements for the description of charge transport and charge storage in disordered media with emphasis on the case of polyethylene. A quick review of available conduction models is presented and our approach is compared with these models. Then, the bases of the model are described and related assumptions are discussed. Finally, results on external current, trapped and free space charge distributions, field distribution and recombination rate are presented and discussed, considering a constant dc voltage, a step-increase of the voltage, and a polarization-depolarization protocol for the applied voltage. It is shown that the model is able to describe the general features reported for external current, electroluminescence and charge distribution in polyethylene.

Attacking the information access problem with expert systems

NASA Technical Reports Server (NTRS)

Ragusa, James M.; Orwig, Gary W.

1991-01-01

The results of applications research directed at finding an improved method of storing and accessing information are presented. Twelve microcomputer-based expert systems shells and five laser-optical formats have been studied, and the general and specific methods of interfacing these technologies are being tested in prototype systems. Shell features and interfacing capabilities are discussed, and results from the study of five laser-optical formats are recounted including the video laser, compact, and WORM disks, and laser cards and film. Interfacing, including laser disk device driver interfacing, is discussed and it is pointed out that in order to control the laser device from within the expert systems application, the expert systems shell must be able to access the device driver software. Potential integrated applications are investigated and an initial list is provided including consumer services, travel, law enforcement, human resources, marketing, and education and training.

Heritage language and linguistic theory

PubMed Central

Scontras, Gregory; Fuchs, Zuzanna; Polinsky, Maria

2015-01-01

This paper discusses a common reality in many cases of multilingualism: heritage speakers, or unbalanced bilinguals, simultaneous or sequential, who shifted early in childhood from one language (their heritage language) to their dominant language (the language of their speech community). To demonstrate the relevance of heritage linguistics to the study of linguistic competence more broadly defined, we present a series of case studies on heritage linguistics, documenting some of the deficits and abilities typical of heritage speakers, together with the broader theoretical questions they inform. We consider the reorganization of morphosyntactic feature systems, the reanalysis of atypical argument structure, the attrition of the syntax of relativization, and the simplification of scope interpretations; these phenomena implicate diverging trajectories and outcomes in the development of heritage speakers. The case studies also have practical and methodological implications for the study of multilingualism. We conclude by discussing more general concepts central to linguistic inquiry, in particular, complexity and native speaker competence. PMID:26500595

The Firework of Electromagnetic Counterparts from GW170817

NASA Astrophysics Data System (ADS)

Siegel, Daniel

2018-01-01

The gravitational-wave signal of the binary neutron star merger GW170817 was followed by a firework of electromagnetic transients across the entire electromagnetic spectrum. The gamma-ray emission has provided strong evidence for the association of short gamma-ray bursts (SGRBs) with binary neutron star mergers and the ultraviolet, optical, and near-infrared emission is consistent with a kilonova indicative of the formation of heavy elements in the merger ejecta by the rapid neutron capture process (r-process). In this talk, I will discuss and review theoretical scenarios to interpret the gamma-ray, X-ray, and radio observations. I will present recent results from general-relativistic magnetohydrodynamic simulations and discuss possible scenarios and mass ejection mechanisms that can give rise to the observed kilonova features. In particular, I will argue that massive winds from neutrino-cooled post-merger accretion disks most likely synthesized the heavy r-process elements in GW170817.

Nanoscale invaginations of the nuclear envelope: Shedding new light on wormholes with elusive function.

PubMed

Schoen, Ingmar; Aires, Lina; Ries, Jonas; Vogel, Viola

2017-09-03

Recent advances in fluorescence microscopy have opened up new possibilities to investigate chromosomal and nuclear 3D organization on the nanoscale. We here discuss their potential for elucidating topographical details of the nuclear lamina. Single molecule localization microscopy (SMLM) in combination with immunostainings of lamina proteins readily reveals tube-like invaginations with a diameter of 100-500 nm. Although these invaginations have been established as a frequent and general feature of interphase nuclei across different cell types, their formation mechanism and function have remained largely elusive. We critically review the current state of research, propose possible connections to lamina associated domains (LADs), and revisit the discussion about the potential role of these invaginations for accelerating mRNA nuclear export. Illustrative studies using 3D super-resolution imaging are shown and will be instrumental to decipher the physiological role of these nanoscale invaginations.

Pseudomonas aeruginosa Biofilm, a Programmed Bacterial Life for Fitness.

PubMed

Lee, Keehoon; Yoon, Sang Sun

2017-06-28

A biofilm is a community of microbes that typically inhabit on surfaces and are encased in an extracellular matrix. Biofilms display very dissimilar characteristics to their planktonic counterparts. Biofilms are ubiquitous in the environment and influence our lives tremendously in both positive and negative ways. Pseudomonas aeruginosa is a bacterium known to produce robust biofilms. P. aeruginosa biofilms cause severe problems in immunocompromised patients, including those with cystic fibrosis or wound infection. Moreover, the unique biofilm properties further complicate the eradication of the biofilm infection, leading to the development of chronic infections. In this review, we discuss the history of biofilm research and general characteristics of bacterial biofilms. Then, distinct features pertaining to each stage of P. aeruginosa biofilm development are highlighted. Furthermore, infections caused by biofilms on their own or in association with other bacterial species ( i.e. , multispecies biofilms) are discussed in detail.

Representations of energy policy and technology in British and Finnish newspaper media: a comparative perspective.

PubMed

Teräväinen, Tuula

2014-04-01

This article analyses media representations of the strengthening technological energy policy orientation in the UK and Finland. Drawing from over 1200 newspaper articles from 1991 to 2006, it scrutinises how energy policy in general and energy technologies in particular have been discussed by the media in these two countries, and how the media representations have changed over time. The results point to the importance of national political, economic and cultural features in shaping media discussions. At the same time, international political events and ideas of technology-driven economic growth have transformed media perceptions of energy technologies. While the British media have been rather critical towards national policies throughout the period of analysis, the Finnish newspaper Helsingin Sanomat has supported successive national governments. In both countries, energy technologies have increasingly become linked to global societal and political questions.

What next after determinism in the ontology of technology? Distributing responsibility in the biofuel debate.

PubMed

Boucher, Philip

2011-09-01

This article builds upon previous discussion of social and technical determinisms as implicit positions in the biofuel debate. To ensure these debates are balanced, it has been suggested that they should be designed to contain a variety of deterministic positions. Whilst it is agreed that determinism does not feature strongly in contemporary academic literatures, it is found that they have generally been superseded by an absence of any substantive conceptualisation of how the social shaping of technology may be related to, or occur alongside, an objective or autonomous reality. The problem of determinism emerges at an ontological level and must be resolved in situ. A critical realist approach to technology is presented which may provide a more appropriate framework for debate. In dialogue with previous discussion, the distribution of responsibility is revisited with reference to the role of scientists and engineers.

Nursing management of reflex anoxic seizures in children.

PubMed

Patel, Neal; Kerr-Liddell, Rowan; Challis, Louise; Paul, Siba Prosad

2017-04-13

Children who present with transient loss of consciousness (T-LOC) are often first seen in emergency departments (EDs). Reflex anoxic seizure (RAS), vasovagal syncope and prolonged respiratory apnoea are benign, syncopal events that can be generally managed by explanation and reassurance. RAS is a short, paroxysmal, self-reverting episode of asystole that is triggered by pain, fear or anxiety and is caused by increased vagal response. It is an important differential diagnosis in pre-school age children who present with T-LOC, but is often underdiagnosed and can sometimes be misdiagnosed as epilepsy. Nurses working in EDs are among the first healthcare professionals to see children in acute settings and should therefore be aware of RAS, the presenting features and management options. This article discusses the epidemiology, pathophysiology and management of RAS, includes an illustrative case study and discusses the role of ED nurses.

[ ] or SUCCESS is Not Enough: Current Technology and Future Directions in Proof Presentation

NASA Technical Reports Server (NTRS)

Schumann, Johann; Robinson, Peter; Clancy, Daniel (Technical Monitor)

2001-01-01

Automated theorem provers for first order logic are now around for several decades. Over the last few years, their deductive power to solve hard problems has increased tremendously. The annual CASC system competitions [Se97] give a clear picture of this situation. However, today's automated theorem provers are restricted "more by general usability than by raw deductive power." As a result of this, there are only very few serious applications of automated theorem provers. There are numerous features which a theorem prover lacks for real-world applicability. An automated theorem prover (as it is currently seen) is nothing more than a fast and elaborate search procedure. In that sense, an ATP can compared to a formulated race car, cool and fast, but virtually unusable for shopping groceries around the corner. Many important features are missing, or are optimized for speed rather than for applicability. [Schol] identifies important features which are needed for practical usability like detection of non-theorems, handling of modal/inductive proof tasks, control of the prover, and proof output. In this paper, we will focus solely on the last point, the presentation of the ATP's result to the user. In the rest of this paper, we will first discuss the general importance of providing feedback to the user, then we will describe the system ExplainIt!, a part of the deductive synthesis system AMPHION/NAV. In the conclusions we will relate proof presentation to other ways of post-processing a proof found by an ATP and stress their role in the future of automated deduction.

Association between MRI structural features and cognitive measures in pediatric multiple sclerosis

NASA Astrophysics Data System (ADS)

Amoroso, N.; Bellotti, R.; Fanizzi, A.; Lombardi, A.; Monaco, A.; Liguori, M.; Margari, L.; Simone, M.; Viterbo, R. G.; Tangaro, S.

2017-09-01

Multiple sclerosis (MS) is an inflammatory and demyelinating disease associated with neurodegenerative processes that lead to brain structural changes. The disease affects mostly young adults, but 3-5% of cases has a pediatric onset (POMS). Magnetic Resonance Imaging (MRI) is generally used for diagnosis and follow-up in MS patients, however the most common MRI measures (e.g. new or enlarging T2-weighted lesions, T1-weighted gadolinium- enhancing lesions) have often failed as surrogate markers of MS disability and progression. MS is clinically heterogenous with symptoms that can include both physical changes (such as visual loss or walking difficulties) and cognitive impairment. 30-50% of POMS experience prominent cognitive dysfunction. In order to investigate the association between cognitive measures and brain morphometry, in this work we present a fully automated pipeline for processing and analyzing MRI brain scans. Relevant anatomical structures are segmented with FreeSurfer; besides, statistical features are computed. Thus, we describe the data referred to 12 patients with early POMS (mean age at MRI: 15.5 +/- 2.7 years) with a set of 181 structural features. The major cognitive abilities measured are verbal and visuo-spatial learning, expressive language and complex attention. Data was collected at the Department of Basic Sciences, Neurosciences and Sense Organs, University of Bari, and exploring different abilities like the verbal and visuo-spatial learning, expressive language and complex attention. Different regression models and parameter configurations are explored to assess the robustness of the results, in particular Generalized Linear Models, Bayes Regression, Random Forests, Support Vector Regression and Artificial Neural Networks are discussed.

Dependent Measure and Time Constraints Modulate the Competition between Conflicting Feature-Based and Rule-Based Generalization Processes

ERIC Educational Resources Information Center

Cobos, Pedro L.; Gutiérrez-Cobo, María J.; Morís, Joaquín; Luque, David

2017-01-01

In our study, we tested the hypothesis that feature-based and rule-based generalization involve different types of processes that may affect each other producing different results depending on time constraints and on how generalization is measured. For this purpose, participants in our experiments learned cue-outcome relationships that followed…

Malignancy in Children with Trisomy 21

PubMed Central

Rabin, Karen R.; Whitlock, James A.

2009-01-01

Patients with Down syndrome (DS) display a unique spectrum of malignancies, with a 10 to 20-fold increased risk of acute leukemias, and a markedly decreased incidence of solid tumors. This review discusses current understanding of the basis for this distinctive pattern of cancer incidence, and the clinical and biologic features of the malignant disorders most frequent in DS: transient myeloproliferative disease, acute megakaryoblastic leukemia, and acute lymphoblastic leukemia. We also review distinctive pharmacogenetic issues, highlighting the differential chemosensitivity and toxicity profiles of DS patients compared to the general population; and epidemiologic studies of protective and adverse environmental risk factors for development of leukemia. PMID:19176633

Chronic pancreatitis.

PubMed

Majumder, Shounak; Chari, Suresh T

2016-05-07

Chronic pancreatitis describes a wide spectrum of fibro-inflammatory disorders of the exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms. Use of the term chronic pancreatitis without qualification generally refers to calcifying chronic pancreatitis. Epidemiology is poorly defined, but incidence worldwide seems to be on the rise. Smoking, drinking alcohol, and genetic predisposition are the major risk factors for chronic calcifying pancreatitis. In this Seminar, we discuss the clinical features, diagnosis, and management of chronic calcifying pancreatitis, focusing on pain management, the role of endoscopic and surgical intervention, and the use of pancreatic enzyme-replacement therapy. Management of patients is often challenging and necessitates a multidisciplinary approach. Copyright © 2016 Elsevier Ltd. All rights reserved.

Characteristics of Spirituality and Religion Among Suicide Attempters.

PubMed

Mandhouj, Olfa; Perroud, Nader; Hasler, Roland; Younes, Nadia; Huguelet, Philippe

2016-11-01

Spirituality and religiousness are associated with a lower risk of suicide. A detailed assessment of spirituality among 88 suicide attempters hospitalized after a suicide attempt was performed. Factors associated with the recurrence of suicide attempts over 18 months were looked into. Spirituality was low among most suicide attempters in comparison with the general population. Two groups were identified: those with a high score of depression who featured "low" in spirituality and those with a more heterogeneous profile, for example, involving personality disorders, characterized by a "high" spirituality. At the follow-up, the "meaning in life" score appeared to correlate with recurrence of suicide. Clinical implications are discussed herein.

STAGS Example Problems Manual

NASA Technical Reports Server (NTRS)

Knight, Norman F., Jr.; Rankin, Charles C.

2006-01-01

This document summarizes the STructural Analysis of General Shells (STAGS) development effort, STAGS performance for selected demonstration problems, and STAGS application problems illustrating selected advanced features available in the STAGS Version 5.0. Each problem is discussed including selected background information and reference solutions when available. The modeling and solution approach for each problem is described and illustrated. Numerical results are presented and compared with reference solutions, test data, and/or results obtained from mesh refinement studies. These solutions provide an indication of the overall capabilities of the STAGS nonlinear finite element analysis tool and provide users with representative cases, including input files, to explore these capabilities that may then be tailored to other applications.

Medical school libraries in the United States and Canada built between 1961 and 1971.

PubMed Central

Beatty, W K; Beatty, V L

1975-01-01

Twenty-four medical school libraries in the United States and Canada built between 1961 and 1971 were surveyed by means of questionnaires and visits. Results indicated that half of these libraries will have reached maximum functional capacity approximately six years after they moved into their new quarters. Space for technical processing is generally much less than required. Special features and examples of effective planning are described, and problems in arrangement, traffic patterns for people and materials, and the lack of logical expansion space are discussed. Comparisons are made with a similar survey of twenty medical school libraries made in 1961. Images PMID:1191825

Development of the Data Acquisition and Processing System for a Pulsed 2-Micron Coherent Doppler Lidar System

NASA Technical Reports Server (NTRS)

Beyon, Jeffrey Y.; Koch, Grady J.; Kavaya, Michael J.

2010-01-01

A general overview of the development of a data acquisition and processing system is presented for a pulsed, 2-micron coherent Doppler Lidar system located in NASA Langley Research Center in Hampton, Virginia, USA. It is a comprehensive system that performs high-speed data acquisition, analysis, and data display both in real time and offline. The first flight missions are scheduled for the summer of 2010 as part of the NASA Genesis and Rapid Intensification Processes (GRIP) campaign for the study of hurricanes. The system as well as the control software is reviewed and its requirements and unique features are discussed.

Short-memory traders and their impact on group learning in financial markets

PubMed Central

LeBaron, Blake

2002-01-01

This article highlights several issues from simulating agent-based financial markets. These all center around the issue of learning in a multiagent setting, and specifically the question of whether the trading behavior of short-memory agents could interfere with the learning process of the market as whole. It is shown in a simple example that short-memory traders persist in generating excess volatility and other features common to actual markets. Problems related to short-memory trader behavior can be eliminated by using several different methods. These are discussed along with their relevance to agent-based models in general. PMID:11997443

A GCM simulation of the earth-atmosphere radiation balance for winter and summer

NASA Technical Reports Server (NTRS)

Wu, M. L. C.

1979-01-01

The radiation balance of the earth-atmosphere system simulated by using the general circulation model (GCM) of the Laboratory for Atmospheric Sciences (GLAS) is examined in regards to its graphical distribution, zonally-averaged distribution, and global mean. Most of the main features of the radiation balance at the top of the atmosphere are reasonably simulated, with some differences in the detailed structure of the patterns and intensities for both summer and winter in comparison with values as derived from Nimbus and NOAA (National Oceanic and Atmospheric Administration) satellite observations. Both the capability and defects of the model are discussed.

A malformed child with a recombinant chromosome 7, rec(7) dup p, derived from a maternal pericentric inversion inv(7)(p15q36).

PubMed Central

Delicado, A; Escribano, E; Lopez Pajares, I; Diaz de Bustamante, A; Carrasco, S

1991-01-01

We report a child with facial dysmorphic features, hypoplasia of the external genitalia, intestinal malrotation, congenital cardiac defect, and minor limb anomalies. Chromosome studies showed a recombinant chromosome 7, rec(7) dup p, resulting from a maternal pericentric inversion inv(7)(p15 q36). Thus, this child had partial trisomy 7p in addition to a small distal monosomy 7. The clinical findings are compared with those found in previous reports of trisomy 7p. Finally, some general principles for genetic counselling are discussed. Images PMID:2002483

Understanding antigay bias from a cognitive-affective-behavioral perspective.

PubMed

Callender, Kevin A

2015-01-01

In general, United States citizens have become increasingly more accepting of lesbians and gay men over the past few decades. Despite this shift in public attitudes, antigay bias remains openly tolerated, accepted, practiced, and even defended by a substantial portion of the population. This article reviews why and how antigay bias persists using a cognitive-affective-behavioral perspective that touches on sociocognitive factors such as prejudice and stereotyping, as well as features unique to antigay bias, such as its concealable nature. The article concludes with a discussion of how understanding modern antigay bias through a cognitive-affective-behavioral lens can be applied to reduce discrimination against gays and lesbians.

Universal lineshapes at the crossover between weak and strong critical coupling in Fano-resonant coupled oscillators

NASA Astrophysics Data System (ADS)

Zanotto, Simone; Tredicucci, Alessandro

2016-04-01

In this article we discuss a model describing key features concerning the lineshapes and the coherent absorption conditions in Fano-resonant dissipative coupled oscillators. The model treats on the same footing the weak and strong coupling regimes, and includes the critical coupling concept, which is of great relevance in numerous applications; in addition, the role of asymmetry is thoroughly analyzed. Due to the wide generality of the model, which can be adapted to various frameworks like nanophotonics, plasmonics, and optomechanics, we envisage that the analytical formulas presented here will be crucial to effectively design devices and to interpret experimental results.

Nucleic acid aptamers: an emerging frontier in cancer therapy.

PubMed

Zhu, Guizhi; Ye, Mao; Donovan, Michael J; Song, Erqun; Zhao, Zilong; Tan, Weihong

2012-11-04

The last two decades have witnessed the development and application of nucleic acid aptamers in a variety of fields, including target analysis, disease therapy, and molecular and cellular engineering. The efficient and widely applicable aptamer selection, reproducible chemical synthesis and modification, generally impressive target binding selectivity and affinity, relatively rapid tissue penetration, low immunogenicity, and rapid systemic clearance make aptamers ideal recognition elements for use as therapeutics or for in vivo delivery of therapeutics. In this feature article, we discuss the development and biomedical application of nucleic acid aptamers, with emphasis on cancer cell aptamer isolation, targeted cancer therapy, oncology biomarker identification and drug discovery.

Are There Frame-Distortion Contributions to Collision-Induced Absorption and Collision-Induced Light Scattering?

NASA Astrophysics Data System (ADS)

Hohm, Uwe

2007-12-01

Collision-induced spectroscopy, such as collision-induced absorption (CIA) and collision-induced light scattering (CILS), can give valuable information on permanent electric moments, polarizabilities and intermolecular-interaction potentials. In general the collision-induced spectra of the pure rare-gases and their binary mixtures are understood fairly well. However if at least one of the collision partners is a molecule then in some cases the spectra show features which can hardly be explained by current theories which deal with the case of undistorted molecules. Here we discuss the possibility of collision-induced frame distortion as an additional effect to be considered in collision-induced spectroscopy.

Ultraviolet properties of the symbiotic stars

NASA Technical Reports Server (NTRS)

Slovak, M. H.; Lambert, D. L.

1982-01-01

A general discussion of the UV spectra of symbiotic stars, including both the emission lines and the continua, is presented, with AG Pegasi considered as an illustrative example. It is noted that the IUE observations of the symbiotics have revealed UV properties which rival the diversity of the optical features. Nevertheless, the UV data have for the first time permitted the hot component to be studied relatively uncontaminated by the giant companion, which dominates the optical regime. The UV observations provide convincing evidence that many of the symbiotics have hot stellar companions embedded in the enshrouding nebula or accretion shell formed from the wind from one or possibly both of the components.

A genetic algorithm used for solving one optimization problem

NASA Astrophysics Data System (ADS)

Shipacheva, E. N.; Petunin, A. A.; Berezin, I. M.

2017-12-01

A problem of minimizing the length of the blank run for a cutting tool during cutting of sheet materials into shaped blanks is discussed. This problem arises during the preparation of control programs for computerized numerical control (CNC) machines. A discrete model of the problem is analogous in setting to the generalized travelling salesman problem with limitations in the form of precursor conditions determined by the technological features of cutting. A certain variant of a genetic algorithm for solving this problem is described. The effect of the parameters of the developed algorithm on the solution result for the problem with limitations is investigated.

Biomarkers of Osteosarcoma, Chondrosarcoma, and Ewing Sarcoma.

PubMed

Evola, Francesco R; Costarella, Luciano; Pavone, Vito; Caff, Giuseppe; Cannavò, Luca; Sessa, Andrea; Avondo, Sergio; Sessa, Giuseppe

2017-01-01

Osteosarcoma is the most frequent malignant bone neoplasm, followed by chondrosarcoma and Ewing sarcoma. The diagnosis of bone neoplasms is generally made through histological evaluation of a biopsy. Clinical and radiological features are also important in aiding diagnosis and to complete the staging of bone cancer. In addition to these, there are several non-specific serological or specific molecular markers for bone neoplasms. In bone tumors, molecular markers increase the accuracy of the diagnosis and assist in subtyping bone tumors. Here, we review these markers and discuss their role in the diagnosis and prognosis of the three most frequent malignant bone neoplasms, namely osteosarcoma, chondrosarcoma, and Ewing sarcoma.

Performance improvement in remote manipulation with time delay by means of a learning system.

NASA Technical Reports Server (NTRS)

Freedy, A.; Weltman, G.

1973-01-01

A teleoperating system is presented that involves shared control between a human operator and a general-purpose computer-based learning machine. This setup features a trainable control network termed the autonomous control subsystem (ACS) which is able to observe the operator's control actions, learn the task at hand, and take appropriate control actions. A working ACS system is described that has been put in operation for the purpose of exploring the uses of a remote intelligence of this type. The expansion of the present system into a multifunctional learning machine capable of a greater degree of autonomy is also discussed.

Library activities in the U.S. and the Western Europe : Trends and features in the recent information management system

NASA Astrophysics Data System (ADS)

Takayama, Masaya

This author reports the discussion and resolutions from the annual meeting of the Special Libraries Association at New York City in the U.S. and the General Conference of the International Federation of Library Associations and Institutions at Paris in France in 1989. Moreover this author visited American libraries after the S.L.A.meeting, and French and British libraries after the IFLA Conference. Based on these library tours, this author concludes that Japanese librarians and information specialists need to know the needs of the application of new information network technologies to the routine works of information management in Japan.

The Cretaceous/Tertiary (K/T) boundary: 25 Years of controversial discussion

NASA Astrophysics Data System (ADS)

Harting, M.; Wittler, F. A.

2006-05-01

The K/T transition is under geoscientific focus since many years. Ever since the discovery of the Chicxulub- Impact theory in the early 1980s, its ctrater and its subsurface structure in the late 1990s many scientists and media, Hollywood, and the general public have become convinced that a large meteorite caused the K/T boundary and killed the dinosaurs and other organisms in the late Maastrichtian. However, today a much more comprehensive and detailed scientific background is present. Many scientist today believe that there is doubt that the Chicxulub impact is the "smoking gun". Moreover, there is increasing evidence that the Chicxulub impact predates the K/T mass extinction by about 300.000 years and did not cause the end of the dinosaures or of other marine and terrestrial organisms. On the other hand, some scientist still fixed to the general theory of a catastropic event. Due to recent field work on highly important sites and drillings inside the Chicxulub Impact structure itself, major new results are present today. In general, these new evidence, such as multiple ejecta layer, in locations in the Gulf of Mexico, the Caribbean, the Tethys and beyond, could not be interpreted by secondary (e.g. sedimentological-) features (slumping, reworking). Unfortunately, due to the highly emotional and controversal discussion - sometimes more like a religious than a scientific fight - many scientist feel uncomfortable to join the K/T problem. In fact, in between only a couple of major groups in various Universities are focussed - and leading - the discussion. A more open interaction between various geoscientific disciplines and researcher may the key to solve the mystery of the Chicxulub Impact and its relation to the K/T boundary.

Cultivating a "chairside manner": dental hypnosis, patient management psychology, and the origins of behavioral dentistry in America, 1890-1910.

PubMed

Andrick, John M

2013-01-01

Discussions regarding the use of hypnotism in dentistry featured prominently in dental journals and society proceedings during the decades around the turn of the twentieth century. Many dentists used hypnotic suggestion either as the sole anesthetic for extractions or in conjunction with local and general anesthetics for excavation and cavity filling. With the heralding of humanitarian dentistry and improved local anesthesia around 1905, a number of dentists advocated using suggestion psychology to calm nervous patients and increase their comfort and satisfaction levels while undergoing dental procedures. The practice of hypnotic suggestion with local and general anesthesia in providing patients with increasingly painless procedures constituted the earliest variety of behavioral dentistry, a discipline not fully developed until the closing decades of the twentieth century. Hypnosis and suggestion became driving forces for psychological applications in the formative years of behavioral dentistry. © 2013 Wiley Periodicals, Inc.

Theoretical investigations on dual-beam illumination electronic speckle pattern interferometry

NASA Astrophysics Data System (ADS)

Goudemand, Nicolas

2006-07-01

Contrary to what is found in most of the existing scientific literature, where a specific frame is developed, the theory of speckle interferometry is (conveniently) presented here as a particular case of the more general theory of holographic interferometry. In addition to the intellectual benefit of dealing with a single unified theory, this brings about many advantages when it comes to discuss fundamental topics such as the three-dimensional evolution of the complex amplitude of the diffuse optical wavefronts, the degree of approximation of the leading formulas, the loss of fringe contrast, the decorrelation effects, the real influence of the terms generally neglected in out-of-focus regions. In the same way, the statistical properties of the speckle fields, usually treated as a separate subject matter, are also integrated in the theory, thus providing a comprehensive knowledge of the qualitative features of speckle interferometry methods, otherwise difficult to understand.

Mental exercising through simple socializing: social interaction promotes general cognitive functioning.

PubMed

Ybarra, Oscar; Burnstein, Eugene; Winkielman, Piotr; Keller, Matthew C; Manis, Melvin; Chan, Emily; Rodriguez, Joel

2008-02-01

Social interaction is a central feature of people's life and engages a variety of cognitive resources. Thus, social interaction should facilitate general cognitive functioning. Previous studies suggest such a link, but they used special populations (e.g., elderly with cognitive impairment), measured social interaction indirectly (e.g., via marital status), and only assessed effects of extended interaction in correlational designs. Here the relation between mental functioning and direct indicators of social interaction was examined in a younger and healthier population. Study 1 using survey methodology found a positive relationship between social interaction, assessed via amount of actual social contact, and cognitive functioning in people from three age groups including younger adults. Study 2 using an experimental design found that a small amount of social interaction (10 min) can facilitate cognitive performance. The findings are discussed in the context of the benefits social relationships have for so many aspects of people's lives.

Negative Urgency Accounts for the Association Between Borderline Personality Features and Intimate Partner Violence in Young Men

PubMed Central

Peters, Jessica R.; Derefinko, Karen J.; Lynam, Donald R.

2016-01-01

Many studies have demonstrated that borderline personality disorder (BPD) is associated with aggression and, in particular, intimate partner violence; however, the mechanisms underlying this association have been less clearly identified. The present study examines the hypothesis that negative urgency (impulsive behavior in response to intense, negative emotions) may explain the specific association between BPD and intimate partner violence. Cross-sectional self-report measures of BPD, violent behavior, and multiple dimensions of impulsivity were administered to 193 undergraduate men. BPD profile scores were associated with both general violence behaviors and intimate partner violence; however, an indirect path via negative urgency existed only with intimate partner violence. No indirect paths from BPD scores were demonstrated via any other factors of impulsivity, although sensation seeking was an independent predictor of general violence. Clinical implications and directions for future research are discussed. PMID:26845532

Socioemotional deficits associated with obsessive-compulsive symptomatology.

PubMed

Grisham, Jessica R; Henry, Julie D; Williams, Alishia D; Bailey, Phoebe E

2010-02-28

Increasing emphasis has been placed on the role of socioemotional functioning in models of obsessive-compulsive disorder (OCD). The present study investigated whether OCD symptoms were associated with capacity for theory of mind (ToM) and basic affect recognition. Non-clinical volunteers (N=204) completed self report measures of OCD and general psychopathology, in addition to behavioral measures of ToM and affect recognition. The results indicated that higher OCD symptoms were associated with reduced ToM, as well as reduced accuracy decoding the specific emotion of disgust. Importantly, these relationships could not be attributed to other, more general features of psychopathology. The findings of the current study therefore further our understanding of how the processing and interpretation of social and emotional information is affected in the context of OCD symptomatology, and are discussed in relation to neuropsychological models of OCD. 2009 Elsevier Ireland Ltd. All rights reserved.

Negative Urgency Accounts for the Association Between Borderline Personality Features and Intimate Partner Violence in Young Men.

PubMed

Peters, Jessica R; Derefinko, Karen J; Lynam, Donald R

2017-02-01

Many studies have demonstrated that borderline personality disorder (BPD) is associated with aggression and, in particular, intimate partner violence; however, the mechanisms underlying this association have been less clearly identified. The present study examines the hypothesis that negative urgency (impulsive behavior in response to intense, negative emotions) may explain the specific association between BPD and intimate partner violence. Cross-sectional self-report measures of BPD, violent behavior, and multiple dimensions of impulsivity were administered to 193 undergraduate men. BPD profile scores were associated with both general violence behaviors and intimate partner violence; however, an indirect path via negative urgency existed only with intimate partner violence. No indirect paths from BPD scores were demonstrated via any other factors of impulsivity, although sensation seeking was an independent predictor of general violence. Clinical implications and directions for future research are discussed.

Representations of non-suicidal self-injury in motion pictures.

PubMed

Trewavas, Christopher; Hasking, Penelope; McAllister, Margaret

2010-01-01

The aim of this study was to investigate representations of non-suicidal self-injury (NSSI) in popular media. Forty-one motion pictures were viewed, coded, and analyzed. NSSI was correlated with mental illness, child maltreatment, and substance abuse. NSSI was generally portrayed as severe, habitual and covert. Further, depictions of NSSI were often sensationalized and featured prominently. NSSI was less likely to be associated with completed suicide than other psychological factors, but more closely associated with suicide than NSSI is in the community. Although NSSI was associated with psychiatric illness, few characters were receiving psychiatric care at the time of NSSI. However a significant proportion received support after engaging in NSSI. The portrayal of NSSI is generally accurate regarding correlates and function, but is inaccurately associated with suicide. Implications of the relatively accurate portrayal of NSSI are discussed in light of the potential for imitation, and the possibility of using cinematherapy to promote effective problem resolution.

Adaptive image contrast enhancement using generalizations of histogram equalization.

PubMed

Stark, J A

2000-01-01

This paper proposes a scheme for adaptive image-contrast enhancement based on a generalization of histogram equalization (HE). HE is a useful technique for improving image contrast, but its effect is too severe for many purposes. However, dramatically different results can be obtained with relatively minor modifications. A concise description of adaptive HE is set out, and this framework is used in a discussion of past suggestions for variations on HE. A key feature of this formalism is a "cumulation function," which is used to generate a grey level mapping from the local histogram. By choosing alternative forms of cumulation function one can achieve a wide variety of effects. A specific form is proposed. Through the variation of one or two parameters, the resulting process can produce a range of degrees of contrast enhancement, at one extreme leaving the image unchanged, at another yielding full adaptive equalization.

Generalized elastica patterns in a curved rotating Hele-Shaw cell

NASA Astrophysics Data System (ADS)

Brandão, Rodolfo; Miranda, José A.

2017-08-01

We study a family of generalized elasticalike equilibrium shapes that arise at the interface separating two fluids in a curved rotating Hele-Shaw cell. This family of stationary interface solutions consists of shapes that balance the competing capillary and centrifugal forces in such a curved flow environment. We investigate how the emerging interfacial patterns are impacted by changes in the geometric properties of the curved Hele-Shaw cell. A vortex-sheet formalism is used to calculate the two-fluid interface curvature, and a gallery of possible shapes is provided to highlight a number of peculiar morphological features. A linear perturbation theory is employed to show that the most prominent aspects of these complex stationary patterns can be fairly well reproduced by the interplay of just two interfacial modes. The connection of these dominant modes to the geometry of the curved cell, as well as to the fluid dynamic properties of the flow, is discussed.

Development and application of General Purpose Data Acquisition Shell (GPDAS) at advanced photon source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chung, Youngjoo; Kim, Keeman.

1991-01-01

An operating system shell GPDAS (General Purpose Data Acquisition Shell) on MS-DOS-based microcomputers has been developed to provide flexibility in data acquisition and device control for magnet measurements at the Advanced Photon Source. GPDAS is both a command interpreter and an integrated script-based programming environment. It also incorporates the MS-DOS shell to make use of the existing utility programs for file manipulation and data analysis. Features include: alias definition, virtual memory, windows, graphics, data and procedure backup, background operation, script programming language, and script level debugging. Data acquisition system devices can be controlled through IEEE488 board, multifunction I/O board, digitalmore » I/O board and Gespac crate via Euro G-64 bus. GPDAS is now being used for diagnostics R D and accelerator physics studies as well as for magnet measurements. Their hardware configurations will also be discussed. 3 refs., 3 figs.« less

A general optimality criteria algorithm for a class of engineering optimization problems

NASA Astrophysics Data System (ADS)

Belegundu, Ashok D.

2015-05-01

An optimality criteria (OC)-based algorithm for optimization of a general class of nonlinear programming (NLP) problems is presented. The algorithm is only applicable to problems where the objective and constraint functions satisfy certain monotonicity properties. For multiply constrained problems which satisfy these assumptions, the algorithm is attractive compared with existing NLP methods as well as prevalent OC methods, as the latter involve computationally expensive active set and step-size control strategies. The fixed point algorithm presented here is applicable not only to structural optimization problems but also to certain problems as occur in resource allocation and inventory models. Convergence aspects are discussed. The fixed point update or resizing formula is given physical significance, which brings out a strength and trim feature. The number of function evaluations remains independent of the number of variables, allowing the efficient solution of problems with large number of variables.

Dissipative discrete breathers: periodic, quasiperiodic, chaotic, and mobile.

PubMed

Martínez, P J; Meister, M; Floría, L M; Falo, F

2003-06-01

The properties of discrete breathers in dissipative one-dimensional lattices of nonlinear oscillators subject to periodic driving forces are reviewed. We focus on oscillobreathers in the Frenkel-Kontorova chain and rotobreathers in a ladder of Josephson junctions. Both types of exponentially localized solutions are easily obtained numerically using adiabatic continuation from the anticontinuous limit. Linear stability (Floquet) analysis allows the characterization of different types of bifurcations experienced by periodic discrete breathers. Some of these bifurcations produce nonperiodic localized solutions, namely, quasiperiodic and chaotic discrete breathers, which are generally impossible as exact solutions in Hamiltonian systems. Within a certain range of parameters, propagating breathers occur as attractors of the dissipative dynamics. General features of these excitations are discussed and the Peierls-Nabarro barrier is addressed. Numerical scattering experiments with mobile breathers reveal the existence of two-breather bound states and allow a first glimpse at the intricate phenomenology of these special multibreather configurations. (c) 2003 American Institute of Physics.

Feature extraction with deep neural networks by a generalized discriminant analysis.

PubMed

Stuhlsatz, André; Lippel, Jens; Zielke, Thomas

2012-04-01

We present an approach to feature extraction that is a generalization of the classical linear discriminant analysis (LDA) on the basis of deep neural networks (DNNs). As for LDA, discriminative features generated from independent Gaussian class conditionals are assumed. This modeling has the advantages that the intrinsic dimensionality of the feature space is bounded by the number of classes and that the optimal discriminant function is linear. Unfortunately, linear transformations are insufficient to extract optimal discriminative features from arbitrarily distributed raw measurements. The generalized discriminant analysis (GerDA) proposed in this paper uses nonlinear transformations that are learnt by DNNs in a semisupervised fashion. We show that the feature extraction based on our approach displays excellent performance on real-world recognition and detection tasks, such as handwritten digit recognition and face detection. In a series of experiments, we evaluate GerDA features with respect to dimensionality reduction, visualization, classification, and detection. Moreover, we show that GerDA DNNs can preprocess truly high-dimensional input data to low-dimensional representations that facilitate accurate predictions even if simple linear predictors or measures of similarity are used.

Feature Modeling of HfO2 Atomic Layer Deposition Using HfCl4/H2O

NASA Astrophysics Data System (ADS)

Stout, Phillip J.; Adams, Vance; Ventzek, Peter L. G.

2003-03-01

A Monte Carlo based feature scale model (Papaya) has been applied to atomic layer deposition (ALD) of HfO2 using HfCl_4/H_20. The model includes physical effects of transport to surface, specular and diffusive reflection within feature, adsorption, surface diffusion, deposition and etching. Discussed will be the 3D feature modeling of HfO2 deposition in assorted features (vias and trenches). The effect of feature aspect ratios, pulse times, cycle number, and temperature on film thickness, feature coverage, and film Cl fraction (surface/bulk) will be discussed. Differences between HfO2 ALD on blanket wafers and in features will be highlighted. For instance, the minimum pulse times sufficient for surface reaction saturation on blanket wafers needs to be increased when depositing on features. Also, HCl products created during the HfCl4 and H_20 pulses are more likely to react within a feature than at the field, reducing OH coverage within the feature (vs blanket wafer) thus limiting the maximum coverage attainable for a pulse over a feature.

Perception of Sentence Stress in Speech Correlates With the Temporal Unpredictability of Prosodic Features.

PubMed

Kakouros, Sofoklis; Räsänen, Okko

2016-09-01

Numerous studies have examined the acoustic correlates of sentential stress and its underlying linguistic functionality. However, the mechanism that connects stress cues to the listener's attentional processing has remained unclear. Also, the learnability versus innateness of stress perception has not been widely discussed. In this work, we introduce a novel perspective to the study of sentential stress and put forward the hypothesis that perceived sentence stress in speech is related to the unpredictability of prosodic features, thereby capturing the attention of the listener. As predictability is based on the statistical structure of the speech input, the hypothesis also suggests that stress perception is a result of general statistical learning mechanisms. To study this idea, computational simulations are performed where temporal prosodic trajectories are modeled with an n-gram model. Probabilities of the feature trajectories are subsequently evaluated on a set of novel utterances and compared to human perception of stress. The results show that the low-probability regions of F0 and energy trajectories are strongly correlated with stress perception, giving support to the idea that attention and unpredictability of sensory stimulus are mutually connected. Copyright © 2015 Cognitive Science Society, Inc.

Computer program for plotting and fairing wind-tunnel data

NASA Technical Reports Server (NTRS)

Morgan, H. L., Jr.

1983-01-01

A detailed description of the Langley computer program PLOTWD which plots and fairs experimental wind-tunnel data is presented. The program was written for use primarily on the Langley CDC computer and CALCOMP plotters. The fundamental operating features of the program are that the input data are read and written to a random-access file for use during program execution, that the data for a selected run can be sorted and edited to delete duplicate points, and that the data can be plotted and faired using tension splines, least-squares polynomial, or least-squares cubic-spline curves. The most noteworthy feature of the program is the simplicity of the user-supplied input requirements. Several subroutines are also included that can be used to draw grid lines, zero lines, axis scale values and lables, and legends. A detailed description of the program operational features and each sub-program are presented. The general application of the program is also discussed together with the input and output for two typical plot types. A listing of the program code, user-guide, and output description are presented in appendices. The program has been in use at Langley for several years and has proven to be both easy to use and versatile.

Scalable learning method for feedforward neural networks using minimal-enclosing-ball approximation.

PubMed

Wang, Jun; Deng, Zhaohong; Luo, Xiaoqing; Jiang, Yizhang; Wang, Shitong

2016-06-01

Training feedforward neural networks (FNNs) is one of the most critical issues in FNNs studies. However, most FNNs training methods cannot be directly applied for very large datasets because they have high computational and space complexity. In order to tackle this problem, the CCMEB (Center-Constrained Minimum Enclosing Ball) problem in hidden feature space of FNN is discussed and a novel learning algorithm called HFSR-GCVM (hidden-feature-space regression using generalized core vector machine) is developed accordingly. In HFSR-GCVM, a novel learning criterion using L2-norm penalty-based ε-insensitive function is formulated and the parameters in the hidden nodes are generated randomly independent of the training sets. Moreover, the learning of parameters in its output layer is proved equivalent to a special CCMEB problem in FNN hidden feature space. As most CCMEB approximation based machine learning algorithms, the proposed HFSR-GCVM training algorithm has the following merits: The maximal training time of the HFSR-GCVM training is linear with the size of training datasets and the maximal space consumption is independent of the size of training datasets. The experiments on regression tasks confirm the above conclusions. Copyright © 2016 Elsevier Ltd. All rights reserved.

Enabling OpenID Authentication for VO-integrated Portals

NASA Astrophysics Data System (ADS)

Plante, R.; Yekkirala, V.; Baker, W.

2012-09-01

To support interoperating services that share proprietary data and other user-specific information, the VAO Project provides login services for browser-based portals built on the open standard, OpenID. To help portal developers take advantage of this service, we have developed a downloadable toolkit for integrating OpenID single sign-on support into any portal. This toolkit provides APIs in a few languages commonly used on the server-side as well as a command-line version for use in any language. In addition to describing how to use this toolkit, we also discuss the general VAO framework for single sign-on. While a portal may, if it wishes, support any OpenID provider, the VAO service provides a few extra features to support VO interoperability. This includes a portal's ability to retrieve (with the user's permission) an X.509 certificate representing the authenticated user so that the portal can access other restricted services on the user's behalf. Other standard features of OpenID allow portals to request other information about the user; this feature will be used in the future for sharing information about a user's group membership to enable sharing within a group of collaborating scientists.

Identifying and Characterizing Kinetic Instabilities using Solar Wind Observations of Non-Maxwellian Plasmas

NASA Astrophysics Data System (ADS)

Klein, K. G.

2016-12-01

Weakly collisional plasmas, of the type typically observed in the solar wind, are commonly in a state other than local thermodynamic equilibrium. This deviation from a Maxwellian velocity distribution can be characterized by pressure anisotropies, disjoint beams streaming at differing speeds, leptokurtic distributions at large energies, and other non-thermal features. As these features may be artifacts of dynamic processes, including the the acceleration and expansion of the solar wind, and as the free energy contained in these features can drive kinetic micro-instabilities, accurate measurement and modeling of these features is essential for characterizing the solar wind. After a review of these features, a technique is presented for the efficient calculation of kinetic instabilities associated with a general, non-Maxwellian plasma. As a proof of principle, this technique is applied to bi-Maxwellian systems for which kinetic instability thresholds are known, focusing on parameter scans including beams and drifting heavy minor ions. The application of this technique to fits of velocity distribution functions from current, forthcoming, and proposed missions including WIND, DSCOVR, Solar Probe Plus, and THOR, as well as the underlying measured distribution functions, is discussed. Particular attention is paid to the effects of instrument pointing and integration time, as well as potential deviation between instabilities associated with the Maxwellian fits and those associated with the observed, potentially non-Maxwellian, velocity distribution. Such application may further illuminate the role instabilities play in the evolution of the solar wind.

Asymmetric statistical features of the Chinese domestic and international gold price fluctuation

NASA Astrophysics Data System (ADS)

Cao, Guangxi; Zhao, Yingchao; Han, Yan

2015-05-01

Analyzing the statistical features of fluctuation is remarkably significant for financial risk identification and measurement. In this study, the asymmetric detrended fluctuation analysis (A-DFA) method was applied to evaluate asymmetric multifractal scaling behaviors in the Shanghai and New York gold markets. Our findings showed that the multifractal features of the Chinese and international gold spot markets were asymmetric. The gold return series persisted longer in an increasing trend than in a decreasing trend. Moreover, the asymmetric degree of multifractals in the Chinese and international gold markets decreased with the increase in fluctuation range. In addition, the empirical analysis using sliding window technology indicated that multifractal asymmetry in the Chinese and international gold markets was characterized by its time-varying feature. However, the Shanghai and international gold markets basically shared a similar asymmetric degree evolution pattern. The American subprime mortgage crisis (2008) and the European debt crisis (2010) enhanced the asymmetric degree of the multifractal features of the Chinese and international gold markets. Furthermore, we also make statistical tests for the results of multifractatity and asymmetry, and discuss the origin of them. Finally, results of the empirical analysis using the threshold autoregressive conditional heteroskedasticity (TARCH) and exponential generalized autoregressive conditional heteroskedasticity (EGARCH) models exhibited that good news had a more significant effect on the cyclical fluctuation of the gold market than bad news. Moreover, good news exerted a more significant effect on the Chinese gold market than on the international gold market.

Ultrasonography of thyroid nodules: a pictorial review.

PubMed

Xie, Cheng; Cox, Peter; Taylor, Nia; LaPorte, Sarah

2016-02-01

Thyroid nodules are a common occurrence in the general population, and these incidental thyroid nodules are often referred for ultrasound (US) evaluation. US provides a safe and fast method of examination. It is sensitive for the detection of thyroid nodules, and suspicious features can be used to guide further investigation/management decisions. However, given the financial burden on the health service and unnecessary anxiety for patients, it is unrealistic to biopsy every thyroid nodule to confirm diagnosis. The British Thyroid Association (BTA) has recently produced a US classification (U1-U5) of thyroid nodules to facilitate the decision-making process regarding the need to perform fine-needle aspiration cytology (FNAC) for suspicious cases. In this pictorial review, we provide a complete series of sonographic images to illustrate benign and malignant features of thyroid nodules according to the U1-5 classification. Specifically, we highlight morphologic characteristic of the nodule, including its echo signal in relation to its consistency, nodular size, number and contour. Additional diagnostic features such as halo, colloid, calcification and vascular patterns are also discussed in detail. The aim is to assist radiologists and clinicians in recognising sonographic patterns of benign, suspicious and malignant nodules based on U1-5 criteria, and in planning for further investigations. • Ultrasound is sensitive in identifying suspicious features, which require aspiration. • Whether nodules require aspiration should be based on sonographic features and clinical findings. • U1-5 classification of sonographic findings can help determine whether aspiration is necessary.

Motions in Prominence Barbs Observed on the Solar Limb

NASA Astrophysics Data System (ADS)

Kucera, T. A.; Ofman, L.; Tarbell, T. D.

2018-06-01

We analyze and discuss an example of prominence barbs observed on the limb on 2016 January 7 by the Hinode/Solar Optical Telescope in Ca II and Hα, the Interface Region Imaging Spectrograph, with slit jaw images and Mg II spectral data, and the Solar Dynamics Observatory’s Atmospheric Imaging Assembly. In the recent literature there has been a debate concerning whether these features, sometimes referred to as “tornadoes,” are rotating. Our data analysis provides no evidence for systematic rotation in the barbs. We do find line-of-sight motions in the barbs that vary with location and time. We also discuss observations of features moving along the barbs. These moving features are elongated parallel to the solar limb and tend to come in clusters of features moving along the same or similar paths in the plane of the sky during a period of 10 minutes to an hour, moving toward or away from the limb. The motion may have a component along the line of sight as well. The spectral data indicate that the features are Doppler shifted. We discuss possible explanations for these features.

Features of Representations in General Chemistry Textbooks: A Peek through the Lens of the Cognitive Load Theory

ERIC Educational Resources Information Center

Nyachwaya, James M.; Gillaspie, Merry

2016-01-01

The goals of this study were (1) determine the prevalence of various features of representations in five general chemistry textbooks used in the United States, and (2) use cognitive load theory to draw implications of the various features of analyzed representations. We adapted the Graphical Analysis Protocol (GAP) (Slough et al., 2010) to look at…

[Diagnosis and differential diagnostic features of gender identity disorder].

PubMed

Kórász, Krisztián; Simon, Lajos

2008-01-01

Gender identity disorder, or transsexualism as it is more commonly known, is a highly complex clinical entity. It is an identifiable and incapacitating disease which can be diagnosed and successfully treated by reassignment surgery. The diagnosis of gender identity disorder can be a difficult process. Transsexual patients will have to undergo extensive psychiatric assessment. The authors review the development of nosology of transsexualism. The current classification systems, symptoms and diagnostic features of gender identity disorders are discussed. The article also discusses differential diagnostic features, like intersex states, psychosis, transvestitism, autogynephilia, gynandromorphophilia, and self-amputation. The authors also discuss the problem of comorbidity, as well.

Containerless protein crystal growth method

NASA Technical Reports Server (NTRS)

Rhim, Won-Kyu; Chung, Sang K.

1991-01-01

A method of growing protein crystals from levitated drops is introduced and unique features of containerless approach in 1-g and micro-G laboratories are discussed. Electrostatic multidrop levitation system which is capable of simultaneous four drop levitation is described. A method of controlling protein saturation level in a programmed way is introduced and discussed. Finally, some of the unique features of containerless approach of protein crystal growth in space are discussed and summarized.

MEVTV Workshop on Tectonic Features on Mars

NASA Technical Reports Server (NTRS)

Watters, Thomas R. (Editor); Golombek, Matthew P. (Editor)

1989-01-01

The state of knowledge of tectonic features on Mars was determined and kinematic and mechanical models were assessed for their origin. Three sessions were held: wrinkle ridges and compressional structure; strike-slip faults; and extensional structures. Each session began with an overview of the features under discussion. In the case of wrinkle ridges and extensional structures, the overview was followed by keynote addresses by specialists working on similar structures on the Earth. The first session of the workshop focused on the controversy over the relative importance of folding, faulting, and intrusive volcanism in the origin of wrinkle ridges. The session ended with discussions of the origin of compressional flank structures associated with Martian volcanoes and the relationship between the volcanic complexes and the inferred regional stress field. The second day of the workshop began with the presentation and discussion of evidence for strike-slip faults on Mars at various scales. In the last session, the discussion of extensional structures ranged from the origin of grabens, tension cracks, and pit-crater chains to the origin of Valles Marineris canyons. Shear and tensile modes of brittle failure in the formation of extensional features and the role of these failure modes in the formation of pit-crater chains and the canyons of Valles Marineris were debated. The relationship of extensional features to other surface processes, such as carbonate dissolution (karst) were also discussed.

Nonlinear features for product inspection

NASA Astrophysics Data System (ADS)

Talukder, Ashit; Casasent, David P.

1999-03-01

Classification of real-time X-ray images of randomly oriented touching pistachio nuts is discussed. The ultimate objective is the development of a system for automated non-invasive detection of defective product items on a conveyor belt. We discuss the extraction of new features that allow better discrimination between damaged and clean items (pistachio nuts). This feature extraction and classification stage is the new aspect of this paper; our new maximum representation and discriminating feature (MRDF) extraction method computes nonlinear features that are used as inputs to a new modified k nearest neighbor classifier. In this work, the MRDF is applied to standard features (rather than iconic data). The MRDF is robust to various probability distributions of the input class and is shown to provide good classification and new ROC (receiver operating characteristic) data.

Clarifying Interpersonal Heterogeneity in Borderline Personality Disorder Using Latent Mixture Modeling

PubMed Central

Wright, Aidan G.C.; Hallquist, Michael N.; Morse, Jennifer Q.; Scott, Lori N.; Stepp, Stephanie D.; Nolf, Kimberly A.; Pilkonis, Paul A.

2013-01-01

Significant interpersonal impairment is a cardinal feature of borderline personality disorder (BPD). However, past research has demonstrated that the interpersonal profile associated with BPD varies across samples, evidence for considerable interpersonal heterogeneity. The current study used Inventory of Interpersonal Problems – Circumplex (IIP-C; Alden, Wiggins, & Pincus, 1990) scale scores to investigate interpersonal inhibitions and excesses in a large sample (N = 255) selected for significant borderline pathology. Results indicated that BPD symptom counts were unrelated to the primary dimensions of the IIP-C, but were related to generalized interpersonal distress. A latent class analysis clarified this finding by revealing six homogeneous interpersonal classes with prototypical profiles associated with Intrusive, Vindictive, Avoidant, Nonassertive, and moderate and severe Exploitable interpersonal problems. These classes differed in clinically relevant features (e.g., antisocial behaviors, self-injury, past suicide attempts). Findings are discussed in terms of the incremental clinical utility of the interpersonal circumplex model and the implications for developmental and nosological models of BPD. PMID:23514179

The application of S-transformation and M-2DPCA in I.C. Engine fault diagnosis

NASA Astrophysics Data System (ADS)

Zhang, Shixiong; Cai, Yanping; Mu, Weijie

2017-04-01

According to the problem of parameter selection and feature extraction for vibration diagnosis of traditional internal combustion engine is discussed. The method based on S-transformation and Module Two Dimensional Principal Components Analysis (M-2DPCA) is proposed to carry out fault diagnosis of I.C. Engine valve mechanism. First of all, the method transfers cylinder surface vibration signals of I.C. into images through S-transform. The second, extracting the optimized projection vectors from the general distribution matrix G which is obtained by all sample sub-images, so that vibration spectrum images can be modularized using M-2DPCA. The last, these features matrix obtained from images project will served as the enters of nearest neighbor classifier, it is used to achieve fault types' division. The method is applied to the diagnosis example of the vibration signal of the valve mechanism eight operating modes, recognition rate up to 94.17 percent; the effectiveness of the proposed method is proved.

What are the most promising strategies for the therapeutic immunomodulation of allergic diseases?

PubMed

Tokura, Y; Röcken, M; Clark, R A; Haliasos, E; Takigawa, M; Sinha, A A

2001-04-01

Specific immunotherapy and other immunomodulatory strategies have long been a stronghold in the management of allergic diseases. In particular, "immunodeviation-therapy" or "vaccination for allergies", i.e. the redirection of Th2-type immune responses towards a Th1-response pattern, has become an ever more popular concept. The present feature of CONTROVERSIES complements our previous discussion of atopy (Röcken et al., Exp Dermatol 7: 97--104, 1998), and is dedicated to a critical analysis of the general problems and limitations one faces with the main immunomodulatory strategies traditionally considered in this context. We also explore alternative approaches that appear promising in order to achieve both a more effective and/or a more specific immunotherapy of allergic diseases. Given that the mast cell remains a key protagonist in the pathogenesis of allergic diseases finally, this feature examines how innovative, more selectively mast cell-targeted strategies may be developed for the management of allergic diseases.

Chaos emerging in soil failure patterns observed during tillage: Normalized deterministic nonlinear prediction (NDNP) and its application.

PubMed

Sakai, Kenshi; Upadhyaya, Shrinivasa K; Andrade-Sanchez, Pedro; Sviridova, Nina V

2017-03-01

Real-world processes are often combinations of deterministic and stochastic processes. Soil failure observed during farm tillage is one example of this phenomenon. In this paper, we investigated the nonlinear features of soil failure patterns in a farm tillage process. We demonstrate emerging determinism in soil failure patterns from stochastic processes under specific soil conditions. We normalized the deterministic nonlinear prediction considering autocorrelation and propose it as a robust way of extracting a nonlinear dynamical system from noise contaminated motion. Soil is a typical granular material. The results obtained here are expected to be applicable to granular materials in general. From a global scale to nano scale, the granular material is featured in seismology, geotechnology, soil mechanics, and particle technology. The results and discussions presented here are applicable in these wide research areas. The proposed method and our findings are useful with respect to the application of nonlinear dynamics to investigate complex motions generated from granular materials.

Uncertain viscoelastic models with fractional order: A new spectral tau method to study the numerical simulations of the solution

NASA Astrophysics Data System (ADS)

Ahmadian, A.; Ismail, F.; Salahshour, S.; Baleanu, D.; Ghaemi, F.

2017-12-01

The analysis of the behaviors of physical phenomena is important to discover significant features of the character and the structure of mathematical models. Frequently the unknown parameters involve in the models are assumed to be unvarying over time. In reality, some of them are uncertain and implicitly depend on several factors. In this study, to consider such uncertainty in variables of the models, they are characterized based on the fuzzy notion. We propose here a new model based on fractional calculus to deal with the Kelvin-Voigt (KV) equation and non-Newtonian fluid behavior model with fuzzy parameters. A new and accurate numerical algorithm using a spectral tau technique based on the generalized fractional Legendre polynomials (GFLPs) is developed to solve those problems under uncertainty. Numerical simulations are carried out and the analysis of the results highlights the significant features of the new technique in comparison with the previous findings. A detailed error analysis is also carried out and discussed.

A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports.

PubMed

Jayachandran, S; Kumar, M Suresh

2016-01-01

Osteopetrosis is a rare genetic bone disorder arising due to a defect in the differentiation or function of osteoclast which results in a generalized increase in bone mass. Osteomyelitis is one of the most common complications because of decreased bone marrow function and compromised blood supply. Radiologist plays a vital role in diagnosing osteopetrosis. Here, we present two cases of autosomal dominant osteopetrosis Type II (ADO II) with secondary osteomyelitis changes which were reported to our department. One of these two cases presented with secondary osteomyelitis in both maxilla and mandible and features of rickets, which is very rarely seen in ADO II. To the best of our knowledge, the presentation of rickets with ADO is the first of its kind to be reported. In this paper, we describe the clinical and radiological features leading to the diagnosis of ADO in these two patients. Further, a review of the literature regarding ADO is discussed.

Opportunities and barriers to establishing a cell therapy programme in South Africa

PubMed Central

2013-01-01

The establishment of a cell therapy programme in South Africa has the potential to contribute to the alleviation of the country’s high disease burden and also to contribute to economic growth. South Africa has various positive attributes that favour the establishment of such a high-profile venture; however, there are also significant obstacles which need to be overcome. We discuss the positive and negative features of the current health biotechnology sector. The positive factors include a strong market pull and a highly innovative scientific and medical community, while the most problematic features include the lack of human resources and education and limited funding. The South African Government has undertaken to strengthen the biotechnology sector in general, but a focus on cell therapy is lacking. The next important step would be to provide financial, legal/ethical and other support for groups that are active and productive in this field through the development of a local cell therapy programme. PMID:23719318

Uncertain decision tree inductive inference

NASA Astrophysics Data System (ADS)

Zarban, L.; Jafari, S.; Fakhrahmad, S. M.

2011-10-01

Induction is the process of reasoning in which general rules are formulated based on limited observations of recurring phenomenal patterns. Decision tree learning is one of the most widely used and practical inductive methods, which represents the results in a tree scheme. Various decision tree algorithms have already been proposed such as CLS, ID3, Assistant C4.5, REPTree and Random Tree. These algorithms suffer from some major shortcomings. In this article, after discussing the main limitations of the existing methods, we introduce a new decision tree induction algorithm, which overcomes all the problems existing in its counterparts. The new method uses bit strings and maintains important information on them. This use of bit strings and logical operation on them causes high speed during the induction process. Therefore, it has several important features: it deals with inconsistencies in data, avoids overfitting and handles uncertainty. We also illustrate more advantages and the new features of the proposed method. The experimental results show the effectiveness of the method in comparison with other methods existing in the literature.

Strongly coupled gauge theories: What can lattice calculations teach us?

NASA Astrophysics Data System (ADS)

Hasenfratz, A.; Brower, R. C.; Rebbi, C.; Weinberg, E.; Witzel, O.

2017-12-01

The dynamical origin of electroweak symmetry breaking is an open question with many possible theoretical explanations. Strongly coupled systems predicting the Higgs boson as a bound state of a new gauge-fermion interaction form one class of candidate models. Due to increased statistics, LHC run II will further constrain the phenomenologically viable models in the near future. In the meanwhile it is important to understand the general properties and specific features of the different competing models. In this work we discuss many-flavor gauge-fermion systems that contain both massless (light) and massive fermions. The former provide Goldstone bosons and trigger electroweak symmetry breaking, while the latter indirectly influence the infrared dynamics. Numerical results reveal that such systems can exhibit a light 0++ isosinglet scalar, well separated from the rest of the spectrum. Further, when we set the scale via the vev of electroweak symmetry breaking, we predict a 2 TeV vector resonance which could be a generic feature of SU(3) gauge theories.

Angle Measurement System (AMS) for Establishing Model Pitch and Roll Zero, and Performing Single Axis Angle Comparisons

NASA Technical Reports Server (NTRS)

Crawford, Bradley L.

2007-01-01

The angle measurement system (AMS) developed at NASA Langley Research Center (LaRC) is a system for many uses. It was originally developed to check taper fits in the wind tunnel model support system. The system was further developed to measure simultaneous pitch and roll angles using 3 orthogonally mounted accelerometers (3-axis). This 3-axis arrangement is used as a transfer standard from the calibration standard to the wind tunnel facility. It is generally used to establish model pitch and roll zero and performs the in-situ calibration on model attitude devices. The AMS originally used a laptop computer running DOS based software but has recently been upgraded to operate in a windows environment. Other improvements have also been made to the software to enhance its accuracy and add features. This paper will discuss the accuracy and calibration methodologies used in this system and some of the features that have contributed to its popularity.

Genome-wide chromatin state transitions associated with developmental and environmental cues.

PubMed

Zhu, Jiang; Adli, Mazhar; Zou, James Y; Verstappen, Griet; Coyne, Michael; Zhang, Xiaolan; Durham, Timothy; Miri, Mohammad; Deshpande, Vikram; De Jager, Philip L; Bennett, David A; Houmard, Joseph A; Muoio, Deborah M; Onder, Tamer T; Camahort, Ray; Cowan, Chad A; Meissner, Alexander; Epstein, Charles B; Shoresh, Noam; Bernstein, Bradley E

2013-01-31

Differences in chromatin organization are key to the multiplicity of cell states that arise from a single genetic background, yet the landscapes of in vivo tissues remain largely uncharted. Here, we mapped chromatin genome-wide in a large and diverse collection of human tissues and stem cells. The maps yield unprecedented annotations of functional genomic elements and their regulation across developmental stages, lineages, and cellular environments. They also reveal global features of the epigenome, related to nuclear architecture, that also vary across cellular phenotypes. Specifically, developmental specification is accompanied by progressive chromatin restriction as the default state transitions from dynamic remodeling to generalized compaction. Exposure to serum in vitro triggers a distinct transition that involves de novo establishment of domains with features of constitutive heterochromatin. We describe how these global chromatin state transitions relate to chromosome and nuclear architecture, and discuss their implications for lineage fidelity, cellular senescence, and reprogramming. Copyright © 2013 Elsevier Inc. All rights reserved.

Implementation of a Smart Phone for Motion Analysis.

PubMed

Yodpijit, Nantakrit; Songwongamarit, Chalida; Tavichaiyuth, Nicha

2015-01-01

In today’s information-rich environment, one of the most popular devices is a smartphone. Research has shown significant growth in the use of smartphones and apps all over the world. Accelerometer within smartphone is a motion sensor that can be used to detect human movements. Compared to other major vital signs, gait characteristics represent general health status, and can be determined using smartphones. The objective of the current study is to design and develop the alternative technology that can potentially predict health status and reduce healthcare cost. This study uses a smartphone as a wireless accelerometer for quantifying human motion characteristics from four steps of the system design and development (data acquisition operation, feature extraction algorithm, classifier design, and decision making strategy). Findings indicate that it is possible to extract features from a smartphone’s accelerometer using a peak detection algorithm. Gait characteristics obtain from the peak detection algorithm include stride time, stance time, swing time and cadence. Applications and limitations of this study are also discussed.

A Review and Clarification of the Terms “holistic,” “configural,” and “relational” in the Face Perception Literature

PubMed Central

Piepers, Daniel W.; Robbins, Rachel A.

2012-01-01

It is widely agreed that the human face is processed differently from other objects. However there is a lack of consensus on what is meant by a wide array of terms used to describe this “special” face processing (e.g., holistic and configural) and the perceptually relevant information within a face (e.g., relational properties and configuration). This paper will review existing models of holistic/configural processing, discuss how they differ from one another conceptually, and review the wide variety of measures used to tap into these concepts. In general we favor a model where holistic processing of a face includes some or all of the interrelations between features and has separate coding for features. However, some aspects of the model remain unclear. We propose the use of moving faces as a way of clarifying what types of information are included in the holistic representation of a face. PMID:23413184

Feeding difficulties, a key feature of the Drosophila NDUFS4 mitochondrial disease model

PubMed Central

Foriel, Sarah; Eidhof, Ilse

2018-01-01

ABSTRACT Mitochondrial diseases are associated with a wide variety of clinical symptoms and variable degrees of severity. Patients with such diseases generally have a poor prognosis and often an early fatal disease outcome. With an incidence of 1 in 5000 live births and no curative treatments available, relevant animal models to evaluate new therapeutic regimes for mitochondrial diseases are urgently needed. By knocking down ND-18, the unique Drosophila ortholog of NDUFS4, an accessory subunit of the NADH:ubiquinone oxidoreductase (Complex I), we developed and characterized several dNDUFS4 models that recapitulate key features of mitochondrial disease. Like in humans, the dNDUFS4 KD flies display severe feeding difficulties, an aspect of mitochondrial disorders that has so far been largely ignored in animal models. The impact of this finding, and an approach to overcome it, will be discussed in the context of interpreting disease model characterization and intervention studies. This article has an associated First Person interview with the first author of the paper. PMID:29590638

Genetic Forms of Epilepsies and other Paroxysmal Disorders

PubMed Central

Olson, Heather E.; Poduri, Annapurna; Pearl, Phillip L.

2016-01-01

Genetic mechanisms explain the pathophysiology of many forms of epilepsy and other paroxysmal disorders such as alternating hemiplegia of childhood, familial hemiplegic migraine, and paroxysmal dyskinesias. Epilepsy is a key feature of well-defined genetic syndromes including Tuberous Sclerosis Complex, Rett syndrome, Angelman syndrome, and others. There is an increasing number of singe gene causes or susceptibility factors associated with several epilepsy syndromes, including the early onset epileptic encephalopathies, benign neonatal/infantile seizures, progressive myoclonus epilepsies, genetic generalized and benign focal epilepsies, epileptic aphasias, and familial focal epilepsies. Molecular mechanisms are diverse, and a single gene can be associated with a broad range of phenotypes. Additional features, such as dysmorphisms, head size, movement disorders, and family history may provide clues to a genetic diagnosis. Genetic testing can impact medical care and counseling. We discuss genetic mechanisms of epilepsy and other paroxysmal disorders, tools and indications for genetic testing, known genotype-phenotype associations, the importance of genetic counseling, and a look towards the future of epilepsy genetics. PMID:25192505

Dynamical complexity in a mean-field model of human EEG

NASA Astrophysics Data System (ADS)

Frascoli, Federico; Dafilis, Mathew P.; van Veen, Lennaert; Bojak, Ingo; Liley, David T. J.

2008-12-01

A recently proposed mean-field theory of mammalian cortex rhythmogenesis describes the salient features of electrical activity in the cerebral macrocolumn, with the use of inhibitory and excitatory neuronal populations (Liley et al 2002). This model is capable of producing a range of important human EEG (electroencephalogram) features such as the alpha rhythm, the 40 Hz activity thought to be associated with conscious awareness (Bojak & Liley 2007) and the changes in EEG spectral power associated with general anesthetic effect (Bojak & Liley 2005). From the point of view of nonlinear dynamics, the model entails a vast parameter space within which multistability, pseudoperiodic regimes, various routes to chaos, fat fractals and rich bifurcation scenarios occur for physiologically relevant parameter values (van Veen & Liley 2006). The origin and the character of this complex behaviour, and its relevance for EEG activity will be illustrated. The existence of short-lived unstable brain states will also be discussed in terms of the available theoretical and experimental results. A perspective on future analysis will conclude the presentation.

Neurologic and developmental features of the Smith-Magenis syndrome (del 17p11.2).

PubMed

Gropman, Andrea L; Duncan, Wallace C; Smith, Ann C M

2006-05-01

The Smith-Magenis syndrome is a rare, complex multisystemic disorder featuring, mental retardation and multiple congenital anomalies caused by a heterozygous interstitial deletion of chromosome 17p11.2. The phenotype of Smith-Magenis syndrome is characterized by a distinct pattern of features including infantile hypotonia, generalized complacency and lethargy in infancy, minor skeletal (brachycephaly, brachydactyly) and craniofacial features, ocular abnormalities, middle ear and laryngeal abnormalities including hoarse voice, as well as marked early expressive speech and language delays, psychomotor and growth retardation, and a 24-hour sleep disturbance. A striking neurobehavioral pattern of stereotypies, hyperactivity, polyembolokoilamania, onychotillomania, maladaptive and self-injurious and aggressive behavior is observed with increasing age. The diagnosis of Smith-Magenis syndrome is based upon the clinical recognition of a constellation of physical, developmental, and behavioral features in combination with a sleep disorder characterized by inverted circadian rhythm of melatonin secretion. Many of the features of Smith-Magenis syndrome are subtle in infancy and early childhood, and become more recognizable with advancing age. Infants are described as looking "cherubic" with a Down syndrome-like appearance, whereas with age the facial appearance is that of relative prognathism. Early diagnosis requires awareness of the often subtle clinical and neurobehavioral phenotype of the infant period. Speech delay with or without hearing loss is common. Most children are diagnosed in mid-childhood when the features of the disorder are most recognizable and striking. While improvements in cytogenetic analysis help to bring cases to clinical recognition at an earlier age, this review seeks to increase clinical awareness about Smith-Magenis syndrome by presenting the salient features observed at different ages including descriptions of the neurologic and behavioral features. Detailed review of the circadian rhythm disturbance unique to Smith-Magenis syndrome is presented. Suggestions for management of the behavioral and sleep difficulties are discussed in the context of the authors' personal experience in the setting of an ongoing Smith-Magenis syndrome natural history study.

Generalized Galilean transformations and the measurement problem in the entropic dynamics approach to quantum theory

NASA Astrophysics Data System (ADS)

Johnson, David T.

Quantum mechanics is an extremely successful and accurate physical theory, yet since its inception, it has been afflicted with numerous conceptual difficulties. The primary subject of this thesis is the theory of entropic quantum dynamics (EQD), which seeks to avoid these conceptual problems by interpreting quantum theory from an informational perspective. We begin by reviewing Cox's work in describing probability theory as a means of rationally and consistently quantifying uncertainties. We then discuss how probabilities can be updated according to either Bayes' theorem or the extended method of maximum entropy (ME). After that discussion, we review the work of Caticha and Giffin that shows that Bayes' theorem is a special case of ME. This important result demonstrates that the ME method is the general method for updating probabilities. We then review some motivating difficulties in quantum mechanics before discussing Caticha's work in deriving quantum theory from the approach of entropic dynamics, which concludes our review. After entropic dynamics is introduced, we develop the concepts of symmetries and transformations from an informational perspective. The primary result is the formulation of a symmetry condition that any transformation must satisfy in order to qualify as a symmetry in EQD. We then proceed to apply this condition to the extended Galilean transformation. This transformation is of interest as it exhibits features of both special and general relativity. The transformation yields a gravitational potential that arises from an equivalence of information. We conclude the thesis with a discussion of the measurement problem in quantum mechanics. We discuss the difficulties that arise in the standard quantum mechanical approach to measurement before developing our theory of entropic measurement. In entropic dynamics, position is the only observable. We show how a theory built on this one observable can account for the multitude of measurements present in quantum theory. Furthermore, we show that the Born rule need not be postulated, but can be derived in EQD. Finally, we show how the wave function can be updated by the ME method as the phase is constructed purely in terms of probabilities.

Regulation of Mitochondrial Structure and Dynamics by the Cytoskeleton and Mechanical Factors.

PubMed

Bartolák-Suki, Erzsébet; Imsirovic, Jasmin; Nishibori, Yuichiro; Krishnan, Ramaswamy; Suki, Béla

2017-08-21

Mitochondria supply cells with energy in the form of ATP, guide apoptosis, and contribute to calcium buffering and reactive oxygen species production. To support these diverse functions, mitochondria form an extensive network with smaller clusters that are able to move along microtubules aided by motor proteins. Mitochondria are also associated with the actin network, which is involved in cellular responses to various mechanical factors. In this review, we discuss mitochondrial structure and function in relation to the cytoskeleton and various mechanical factors influencing cell functions. We first summarize the morphological features of mitochondria with an emphasis on fission and fusion as well as how network properties govern function. We then review the relationship between the mitochondria and the cytoskeletal structures, including mechanical interactions. We also discuss how stretch and its dynamic pattern affect mitochondrial structure and function. Finally, we present preliminary data on how extracellular matrix stiffness influences mitochondrial morphology and ATP generation. We conclude by discussing the more general role that mitochondria may play in mechanobiology and how the mechanosensitivity of mitochondria may contribute to the development of several diseases and aging.

Objective measurement of bread crumb texture

NASA Astrophysics Data System (ADS)

Wang, Jian; Coles, Graeme D.

1995-01-01

Evaluation of bread crumb texture plays an important role in judging bread quality. This paper discusses the application of image analysis methods to the objective measurement of the visual texture of bread crumb. The application of Fast Fourier Transform and mathematical morphology methods have been discussed by the authors in their previous work, and a commercial bread texture measurement system has been developed. Based on the nature of bread crumb texture, we compare the advantages and disadvantages of the two methods, and a third method based on features derived directly from statistics of edge density in local windows of the bread image. The analysis of various methods and experimental results provides an insight into the characteristics of the bread texture image and interconnection between texture measurement algorithms. The usefulness of the application of general stochastic process modelling of texture is thus revealed; it leads to more reliable and accurate evaluation of bread crumb texture. During the development of these methods, we also gained useful insights into how subjective judges form opinions about bread visual texture. These are discussed here.

Regulation of Mitochondrial Structure and Dynamics by the Cytoskeleton and Mechanical Factors

PubMed Central

Bartolák-Suki, Erzsébet; Imsirovic, Jasmin; Nishibori, Yuichiro; Krishnan, Ramaswamy; Suki, Béla

2017-01-01

Mitochondria supply cells with energy in the form of ATP, guide apoptosis, and contribute to calcium buffering and reactive oxygen species production. To support these diverse functions, mitochondria form an extensive network with smaller clusters that are able to move along microtubules aided by motor proteins. Mitochondria are also associated with the actin network, which is involved in cellular responses to various mechanical factors. In this review, we discuss mitochondrial structure and function in relation to the cytoskeleton and various mechanical factors influencing cell functions. We first summarize the morphological features of mitochondria with an emphasis on fission and fusion as well as how network properties govern function. We then review the relationship between the mitochondria and the cytoskeletal structures, including mechanical interactions. We also discuss how stretch and its dynamic pattern affect mitochondrial structure and function. Finally, we present preliminary data on how extracellular matrix stiffness influences mitochondrial morphology and ATP generation. We conclude by discussing the more general role that mitochondria may play in mechanobiology and how the mechanosensitivity of mitochondria may contribute to the development of several diseases and aging. PMID:28825689

Selecting the most appropriate inferential statistical test for your quantitative research study.

PubMed

Bettany-Saltikov, Josette; Whittaker, Victoria Jane

2014-06-01

To discuss the issues and processes relating to the selection of the most appropriate statistical test. A review of the basic research concepts together with a number of clinical scenarios is used to illustrate this. Quantitative nursing research generally features the use of empirical data which necessitates the selection of both descriptive and statistical tests. Different types of research questions can be answered by different types of research designs, which in turn need to be matched to a specific statistical test(s). Discursive paper. This paper discusses the issues relating to the selection of the most appropriate statistical test and makes some recommendations as to how these might be dealt with. When conducting empirical quantitative studies, a number of key issues need to be considered. Considerations for selecting the most appropriate statistical tests are discussed and flow charts provided to facilitate this process. When nursing clinicians and researchers conduct quantitative research studies, it is crucial that the most appropriate statistical test is selected to enable valid conclusions to be made. © 2013 John Wiley & Sons Ltd.

Progress on ultrasonic flaw sizing in turbine-engine rotor components: bore and web geometries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rose, J.H.; Gray, T.A.; Thompson, R.B.

1983-01-01

The application of generic flaw-sizing techniques to specific components generally involves difficulties associated with geometrical complexity and simplifications arising from a knowledge of the expected flaw distribution. This paper is concerned with the case of ultrasonic flaw sizing in turbine-engine rotor components. The sizing of flat penny-shaped cracks in the web geometry discussed and new crack-sizing algorithms based on the Born and Kirchhoff approximations are introduced. Additionally, we propose a simple method for finding the size of a flat, penny-shaped crack given only the magnitude of the scattering amplitude. The bore geometry is discussed with primary emphasis on the cylindricalmore » focusing of the incident beam. Important questions which are addressed include the effects of diffraction and the position of the flaw with respect to the focal line. The appropriate deconvolution procedures to account for these effects are introduced. Generic features of the theory are compared with experiment. Finally, the effects of focused transducers on the Born inversion algorithm are discussed.« less

Limited Area Predictability: Is There A Limit To The Operational Usefulness of A Lam

NASA Astrophysics Data System (ADS)

Mesinger, F.

The issue of the limited area predictability in the context of the operational experience of the Eta Model, driven by the LBCs of the NCEP global spectral (Avn) model, is examined. The traditional view is that "the contamination at the lateral boundaries ... limits the operational usefulness of the LAM beyond some forecast time range". In the case of the Eta this contamination consists not only of the lower resolution of the Avn LBCs and the much discussed mathematical "lateral boundary error", but also of the use of the LBCs of the previous Avn run, at 0000 and 1200 UTC estimated to amount to about an 8 h loss in accuracy. Looking for the signs of the Eta accuracy in relative terms falling behind that of the Avn we have examined the trend of the Eta vs Avn precipitation scores, the rms fits to raobs of the two models as a function of time, and the errors of these models at extended forecast times in placing the centers of major lows. In none of these efforts, some including forecasts out to 84 h, we were able to notice signs of the Eta accuracy being visibly affected by the inflow of the lateral boundary errors. It is therefore hypothesized that some of the Eta design features compensate for the increasing influence of the Avn LBC errors. Candidate features are discussed, with the eta coordinate being a contender to play a major role. This situation being possible for the pair of models discussed, existence of a general limit for the operational usefulness of a LAM seems questionable.

Needs and Requirements for Future Research Reactors (ORNL Perspectives)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ilas, Germina; Bryan, Chris; Gehin, Jess C.

2016-02-10

The High Flux Isotope Reactor (HFIR) is a vital national and international resource for neutron science research, production of radioisotopes, and materials irradiation. While HFIR is expected to continue operation for the foreseeable future, interest is growing in understanding future research reactors features, needs, and requirements. To clarify, discuss, and compile these needs from the perspective of Oak Ridge National Laboratory (ORNL) research and development (R&D) missions, a workshop, titled “Needs and Requirements for Future Research Reactors”, was held at ORNL on May 12, 2015. The workshop engaged ORNL staff that is directly involved in research using HFIR to collectmore » valuable input on the reactor’s current and future missions. The workshop provided an interactive forum for a fruitful exchange of opinions, and included a mix of short presentations and open discussions. ORNL staff members made 15 technical presentations based on their experience and areas of expertise, and discussed those capabilities of the HFIR and future research reactors that are essential for their current and future R&D needs. The workshop was attended by approximately 60 participants from three ORNL directorates. The agenda is included in Appendix A. This document summarizes the feedback provided by workshop contributors and participants. It also includes information and insights addressing key points that originated from the dialogue started at the workshop. A general overview is provided on the design features and capabilities of high performance research reactors currently in use or under construction worldwide. Recent and ongoing design efforts in the US and internationally are briefly summarized, followed by conclusions and recommendations.« less

Advanced Techniques for Scene Analysis

DTIC Science & Technology

2010-06-01

robustness prefers a bigger intergration window to handle larger motions. The advantage of pyramidal implementation is that, while each motion vector dL...labeled SAR images. Now the previous algorithm leads to a more dedicated classifier for the particular target; however, our algorithm trades generality for...accuracy is traded for generality. 7.3.2 I-RELIEF Feature weighting transforms the original feature vector x into a new feature vector x′ by assigning each

General Relativistic Radiative Transfer and General Relativistic MHD Simulations of Accretion and Outflows of Black Holes

NASA Technical Reports Server (NTRS)

Fuerst, Steven V.; Mizuno, Yosuke; Nishikawa, Ken-Ichi; Wu, Kinwah

2007-01-01

We have calculated the emission from relativistic flows in black hole systems using a fully general relativistic radiative transfer, with flow structures obtained by general relativistic magnetohydrodynamic simulations. We consider thermal free-free emission and thermal synchrotron emission. Bright filament-like features are found protruding (visually) from the accretion disk surface, which are enhancements of synchrotron emission when the magnetic field is roughly aligned with the line-of-sight in the co-moving frame. The features move back and forth as the accretion flow evolves, but their visibility and morphology are robust. We propose that variations and location drifts of the features are responsible for certain X-ray quasi-periodic oscillations (QPOs) observed in black-hole X-ray binaries.

General Relativistic Radiative Transfer and GeneralRelativistic MHD Simulations of Accretion and Outflows of Black Holes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fuerst, Steven V.; /KIPAC, Menlo Park; Mizuno, Yosuke

2007-01-05

We calculate the emission from relativistic flows in black hole systems using a fully general relativistic radiative transfer formulation, with flow structures obtained by general relativistic magneto-hydrodynamic simulations. We consider thermal free-free emission and thermal synchrotron emission. Bright filament-like features protrude (visually) from the accretion disk surface, which are enhancements of synchrotron emission where the magnetic field roughly aligns with the line-of-sight in the co-moving frame. The features move back and forth as the accretion flow evolves, but their visibility and morphology are robust. We propose that variations and drifts of the features produce certain X-ray quasi-periodic oscillations (QPOs) observedmore » in black-hole X-ray binaries.« less

TRADITIONAL METALLURGY, NANOTECHNOLOGIES AND STRUCTURAL MATERIALS: A SORBY AWARD LECTURE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Louthan, M

2007-07-17

Traditional metallurgical processes are among the many ''old fashion'' practices that use nanoparticles to control the behavior of materials. Many of these practices were developed long before microscopy could resolve nanoscale features, yet the practitioners learned to manipulate and control microstructural elements that they could neither see nor identify. Furthermore, these early practitioners used that control to modify microstructures and develop desired material properties. Centuries old colored glass, ancient high strength steels and medieval organ pipes derived many of their desirable features through control of nanoparticles in their microstructures. Henry Sorby was among the first to recognize that the propertiesmore » of rocks, minerals, metals and organic materials were controlled by microstructure. However, Mr. Sorby was accused of the folly of trying to study mountains with a microscope. Although he could not resolve nanoscale microstructural features, Mr. Sorby's observations revolutionized the study of materials. The importance of nanoscale microstructural elements should be emphasized, however, because the present foundation for structural materials was built by manipulating those features. That foundation currently supports several multibillion dollar industries but is not generally considered when the nanomaterials revolution is discussed. This lecture demonstrates that using nanotechnologies to control the behavior of metallic materials is almost as old as the practice of metallurgy and that many of the emergent nanomaterials technologists are walking along pathways previously paved by traditional metallurgists.« less

New nonlinear features for inspection, robotics, and face recognition

NASA Astrophysics Data System (ADS)

Casasent, David P.; Talukder, Ashit

1999-10-01

Classification of real-time X-ray images of randomly oriented touching pistachio nuts is discussed. The ultimate objective is the development of a system for automated non- invasive detection of defective product items on a conveyor belt. We discuss the extraction of new features that allow better discrimination between damaged and clean items (pistachio nuts). This feature extraction and classification stage is the new aspect of this paper; our new maximum representation and discriminating feature (MRDF) extraction method computes nonlinear features that are used as inputs to a new modified k nearest neighbor classifier. In this work, the MRDF is applied to standard features (rather than iconic data). The MRDF is robust to various probability distributions of the input class and is shown to provide good classification and new ROC (receiver operating characteristic) data. Other applications of these new feature spaces in robotics and face recognition are also noted.

New feature extraction method for classification of agricultural products from x-ray images

NASA Astrophysics Data System (ADS)

Talukder, Ashit; Casasent, David P.; Lee, Ha-Woon; Keagy, Pamela M.; Schatzki, Thomas F.

1999-01-01

Classification of real-time x-ray images of randomly oriented touching pistachio nuts is discussed. The ultimate objective is the development of a system for automated non- invasive detection of defective product items on a conveyor belt. We discuss the extraction of new features that allow better discrimination between damaged and clean items. This feature extraction and classification stage is the new aspect of this paper; our new maximum representation and discrimination between damaged and clean items. This feature extraction and classification stage is the new aspect of this paper; our new maximum representation and discriminating feature (MRDF) extraction method computes nonlinear features that are used as inputs to a new modified k nearest neighbor classifier. In this work the MRDF is applied to standard features. The MRDF is robust to various probability distributions of the input class and is shown to provide good classification and new ROC data.

Object-based selection from spatially-invariant representations: evidence from a feature-report task.

PubMed

Matsukura, Michi; Vecera, Shaun P

2011-02-01

Attention selects objects as well as locations. When attention selects an object's features, observers identify two features from a single object more accurately than two features from two different objects (object-based effect of attention; e.g., Duncan, Journal of Experimental Psychology: General, 113, 501-517, 1984). Several studies have demonstrated that object-based attention can operate at a late visual processing stage that is independent of objects' spatial information (Awh, Dhaliwal, Christensen, & Matsukura, Psychological Science, 12, 329-334, 2001; Matsukura & Vecera, Psychonomic Bulletin & Review, 16, 529-536, 2009; Vecera, Journal of Experimental Psychology: General, 126, 14-18, 1997; Vecera & Farah, Journal of Experimental Psychology: General, 123, 146-160, 1994). In the present study, we asked two questions regarding this late object-based selection mechanism. In Part I, we investigated how observers' foreknowledge of to-be-reported features allows attention to select objects, as opposed to individual features. Using a feature-report task, a significant object-based effect was observed when to-be-reported features were known in advance but not when this advance knowledge was absent. In Part II, we examined what drives attention to select objects rather than individual features in the absence of observers' foreknowledge of to-be-reported features. Results suggested that, when there was no opportunity for observers to direct their attention to objects that possess to-be-reported features at the time of stimulus presentation, these stimuli must retain strong perceptual cues to establish themselves as separate objects.

Computer vision

NASA Technical Reports Server (NTRS)

Gennery, D.; Cunningham, R.; Saund, E.; High, J.; Ruoff, C.

1981-01-01

The field of computer vision is surveyed and assessed, key research issues are identified, and possibilities for a future vision system are discussed. The problems of descriptions of two and three dimensional worlds are discussed. The representation of such features as texture, edges, curves, and corners are detailed. Recognition methods are described in which cross correlation coefficients are maximized or numerical values for a set of features are measured. Object tracking is discussed in terms of the robust matching algorithms that must be devised. Stereo vision, camera control and calibration, and the hardware and systems architecture are discussed.

Kinesiology taping and the world wide web: a quality and content analysis of internet-based information.

PubMed

Beutel, Bryan G; Cardone, Dennis A

2014-10-01

Due to limited regulation of websites, the quality and content of online health-related information has been questioned as prior studies have shown that websites often misrepresent orthopaedic conditions and treatments. Kinesio tape has gained popularity among athletes and the general public despite limited evidence supporting its efficacy. The primary objective of this study was to assess the quality and content of Internet-based information on Kinesio taping. An Internet search using the terms "Kinesio tape" and "kinesiology tape" was performed using the Google search engine. Websites returned within the first two pages of results, as well as hyperlinks embedded within these sites, were included in the study. These sites were subsequently classified by type. The quality of the website was determined by the Health On the Net (HON) score, an objective metric based upon recommendations from the United Nations for the ethical representation of health information. A content analysis was performed by noting specific misleading versus balanced features in each website. A total of 31 unique websites were identified. The majority of the websites (71%) were commercial. Out of a total possible 16 points, the mean HON score among the websites was 8.9 points (SD 2.2 points). The number of misleading features was significantly higher than the balanced features (p < 0.001). Fifty-eight percent of sites used anecdotal testimonials to promote the product. Only small percentages of websites discussed complications, alternatives, or provided accurate medical outcomes. Overall, commercial sites had a greater number of misleading features compared to non-commercial sites (p = 0.01). Websites discussing Kinesio tape are predominantly of poor quality and present misleading, imbalanced information. It is of ever-increasing importance that healthcare providers work to ensure that reliable, balanced, and accurate information be available to Internet users. IV.

Post-acute rehabilitation care for older people in community hospitals and general hospitals--philosophies of care and patients' and caregivers' reported experiences: a qualitative study.

PubMed

Small, Neil; Green, John; Spink, Joanna; Forster, Anne; Young, John

2009-01-01

This article contrasts community hospital and general hospital philosophies of care and examines how they relate to patients' and caregivers' experiences. Semi-structured interviews with 42 staff were used to produce care setting vignettes in six community hospitals and four general hospitals in the midlands and north of England. The vignettes were used with 26 patients and 10 caregivers in semi-structured interviews. Community hospital and general hospital staff identified shared understandings of requirements for post-acute rehabilitation care for older people. Distinctive features were: general hospital--medical efficiency, helping patients get better, high standard of care, need for stimulation; community hospital--home-like setting, quiet, calm ambience, good views, orientated to elderly people, encouragement of social interaction, involvement of relatives in care. In the main there was symmetry between staff aspirations and patients' experience. However some concepts used and assumptions made by staff were not recognised by patients. These were characteristically reframed in patients' answers as if they were discussing subjective dimensions of care. There was patient and caregiver preference for the home-like environment of community hospitals. In care of older people, where the focus is rehabilitation, patient preferences are particularly pertinent and should be considered alongside clinical outcomes and cost-effectiveness.

Bulk renormalization and particle spectrum in codimension-two brane worlds

NASA Astrophysics Data System (ADS)

Salvio, Alberto

2013-04-01

We study the Casimir energy due to bulk loops of matter fields in codimension-two brane worlds and discuss how effective field theory methods allow us to use this result to renormalize the bulk and brane operators. In the calculation we explicitly sum over the Kaluza-Klein (KK) states with a new convenient method, which is based on a combined use of zeta function and dimensional regularization. Among the general class of models we consider we include a supersymmetric example, 6D gauged chiral supergravity. Although much of our discussion is more general, we treat in some detail a class of compactifications, where the extra dimensions parametrize a rugby ball shaped space with size stabilized by a bulk magnetic flux. The rugby ball geometry requires two branes, which can host the Standard Model fields and carry both tension and magnetic flux (of the bulk gauge field), the leading terms in a derivative expansion. The brane properties have an impact on the KK spectrum and therefore on the Casimir energy as well as on the renormalization of the brane operators. A very interesting feature is that when the two branes carry exactly the same amount of flux, one half of the bulk supersymmetries survives after the compactification, even if the brane tensions are large. We also discuss the implications of these calculations for the natural value of the cosmological constant when the bulk has two large extra dimensions and the bulk supersymmetry is partially preserved (or completely broken).

Psychometric Features of the General Aptitude Test-Verbal Part (GAT-V): A Large-Scale Assessment of High School Graduates in Saudi Arabia

ERIC Educational Resources Information Center

Dimitrov, Dimiter M.; Shamrani, Abdul Rahman

2015-01-01

This study examines the psychometric features of a General Aptitude Test-Verbal Part, which is used with assessments of high school graduates in Saudi Arabia. The data supported a bifactor model, with one general factor and three content domains (Analogy, Sentence Completion, and Reading Comprehension) as latent aspects of verbal aptitude.

3D General Circulation Model of the Middle Atmosphere of Jupiter

NASA Astrophysics Data System (ADS)

Zube, Nicholas Gerard; Zhang, Xi; Li, Cheng; Le, Tianhao

2017-10-01

The characteristics of Jupiter’s large-scale stratospheric circulation remain largely unknown. Detailed distributions of temperature and photochemical species have been provided by recent observations [1], but have not yet been accurately reproduced by middle atmosphere general circulation models (GCM). Jupiter’s stratosphere and upper troposphere are influenced by radiative forcing from solar insolation and infrared cooling from hydrogen and hydrocarbons, as well as waves propagating from the underlying troposphere [2]. The relative significance of radiative and mechanical forcing on stratospheric circulation is still being debated [3]. Here we present a 3D GCM of Jupiter’s atmosphere with a correlated-k radiative transfer scheme. The simulation results are compared with observations. We analyze the impact of model parameters on the stratospheric temperature distribution and dynamical features. Finally, we discuss future tracer transport and gravity wave parameterization schemes that may be able to accurately simulate the middle atmosphere dynamics of Jupiter and other giant planets.[1] Kunde et al. 2004, Science 305, 1582.[2] Zhang et al. 2013a, EGU General Assembly, EGU2013-5797-2.[3] Conrath 1990, Icarus, 83, 255-281.

Solar Light Photocatalytic CO2 Reduction: General Considerations and Selected Bench-Mark Photocatalysts

PubMed Central

Neaţu, Ştefan; Maciá-Agulló, Juan Antonio; Garcia, Hermenegildo

2014-01-01

The reduction of carbon dioxide to useful chemicals has received a great deal of attention as an alternative to the depletion of fossil resources without altering the atmospheric CO2 balance. As the chemical reduction of CO2 is energetically uphill due to its remarkable thermodynamic stability, this process requires a significant transfer of energy. Achievements in the fields of photocatalysis during the last decade sparked increased interest in the possibility of using sunlight to reduce CO2. In this review we discuss some general features associated with the photocatalytic reduction of CO2 for the production of solar fuels, with considerations to be taken into account of the photocatalyst design, of the limitations arising from the lack of visible light response of titania, of the use of co-catalysts to overcome this shortcoming, together with several strategies that have been applied to enhance the photocatalytic efficiency of CO2 reduction. The aim is not to provide an exhaustive review of the area, but to present general aspects to be considered, and then to outline which are currently the most efficient photocatalytic systems. PMID:24670477

Solar light photocatalytic CO2 reduction: general considerations and selected bench-mark photocatalysts.

PubMed

Neațu, Stefan; Maciá-Agulló, Juan Antonio; Garcia, Hermenegildo

2014-03-25

The reduction of carbon dioxide to useful chemicals has received a great deal of attention as an alternative to the depletion of fossil resources without altering the atmospheric CO2 balance. As the chemical reduction of CO2 is energetically uphill due to its remarkable thermodynamic stability, this process requires a significant transfer of energy. Achievements in the fields of photocatalysis during the last decade sparked increased interest in the possibility of using sunlight to reduce CO2. In this review we discuss some general features associated with the photocatalytic reduction of CO2 for the production of solar fuels, with considerations to be taken into account of the photocatalyst design, of the limitations arising from the lack of visible light response of titania, of the use of co-catalysts to overcome this shortcoming, together with several strategies that have been applied to enhance the photocatalytic efficiency of CO2 reduction. The aim is not to provide an exhaustive review of the area, but to present general aspects to be considered, and then to outline which are currently the most efficient photocatalytic systems.

A hierarchical model of the evolution of human brain specializations

PubMed Central

Barrett, H. Clark

2012-01-01

The study of information-processing adaptations in the brain is controversial, in part because of disputes about the form such adaptations might take. Many psychologists assume that adaptations come in two kinds, specialized and general-purpose. Specialized mechanisms are typically thought of as innate, domain-specific, and isolated from other brain systems, whereas generalized mechanisms are developmentally plastic, domain-general, and interactive. However, if brain mechanisms evolve through processes of descent with modification, they are likely to be heterogeneous, rather than coming in just two kinds. They are likely to be hierarchically organized, with some design features widely shared across brain systems and others specific to particular processes. Also, they are likely to be largely developmentally plastic and interactive with other brain systems, rather than canalized and isolated. This article presents a hierarchical model of brain specialization, reviewing evidence for the model from evolutionary developmental biology, genetics, brain mapping, and comparative studies. Implications for the search for uniquely human traits are discussed, along with ways in which conventional views of modularity in psychology may need to be revised. PMID:22723350

Signatures of extra dimensions in gravitational waves from black hole quasinormal modes

NASA Astrophysics Data System (ADS)

Chakraborty, Sumanta; Chakravarti, Kabir; Bose, Sukanta; SenGupta, Soumitra

2018-05-01

In this work, we have derived the evolution equation for gravitational perturbation in four-dimensional spacetime in the presence of a spatial extra dimension. The evolution equation is derived by perturbing the effective gravitational field equations on the four-dimensional spacetime, which inherits nontrivial higher-dimensional effects. Note that this is different from the perturbation of the five-dimensional gravitational field equations that exist in the literature and possess quantitatively new features. The gravitational perturbation has further been decomposed into a purely four-dimensional part and another piece that depends on extra dimensions. The four-dimensional gravitational perturbation now admits massive propagating degrees of freedom, owing to the existence of higher dimensions. We have also studied the influence of these massive propagating modes on the quasinormal mode frequencies, signaling the higher-dimensional nature of the spacetime, and have contrasted these massive modes with the massless modes in general relativity. Surprisingly, it turns out that the massive modes experience damping much smaller than that of the massless modes in general relativity and may even dominate over and above the general relativity contribution if one observes the ringdown phase of a black hole merger event at sufficiently late times. Furthermore, the whole analytical framework has been supplemented by the fully numerical Cauchy evolution problem, as well. In this context, we have shown that, except for minute details, the overall features of the gravitational perturbations are captured both in the Cauchy evolution as well as in the analysis of quasinormal modes. The implications on observations of black holes with LIGO and proposed space missions such as LISA are also discussed.

No-reference image quality assessment based on natural scene statistics and gradient magnitude similarity

NASA Astrophysics Data System (ADS)

Jia, Huizhen; Sun, Quansen; Ji, Zexuan; Wang, Tonghan; Chen, Qiang

2014-11-01

The goal of no-reference/blind image quality assessment (NR-IQA) is to devise a perceptual model that can accurately predict the quality of a distorted image as human opinions, in which feature extraction is an important issue. However, the features used in the state-of-the-art "general purpose" NR-IQA algorithms are usually natural scene statistics (NSS) based or are perceptually relevant; therefore, the performance of these models is limited. To further improve the performance of NR-IQA, we propose a general purpose NR-IQA algorithm which combines NSS-based features with perceptually relevant features. The new method extracts features in both the spatial and gradient domains. In the spatial domain, we extract the point-wise statistics for single pixel values which are characterized by a generalized Gaussian distribution model to form the underlying features. In the gradient domain, statistical features based on neighboring gradient magnitude similarity are extracted. Then a mapping is learned to predict quality scores using a support vector regression. The experimental results on the benchmark image databases demonstrate that the proposed algorithm correlates highly with human judgments of quality and leads to significant performance improvements over state-of-the-art methods.

Ad hoc supervision of general practice registrars as a 'community of practice': analysis, interpretation and re-presentation.

PubMed

Clement, T; Brown, J; Morrison, J; Nestel, D

2016-05-01

General practice registrars in Australia undertake most of their vocational training in accredited general practices. They typically see patients alone from the start of their community-based training and are expected to seek timely ad hoc support from their supervisor. Such ad hoc encounters are a mechanism for ensuring patient safety, but also provide an opportunity for learning and teaching. Wenger's (Communities of practice: learning, meaning, and identity. Cambridge University Press, New York, 1998) social theory of learning ('communities of practice') guided a secondary analysis of audio-recordings of ad hoc encounters. Data from one encounter is re-presented as an extended sequence to maintain congruence with the theoretical perspective and enhance vicariousness. An interpretive commentary communicates key features of Wenger's theory and highlights the researchers' interpretations. We argue that one encounter can reveal universal understandings of clinical supervision and that the process of naturalistic generalisation allows readers to transfer others' experiences to their own contexts. The paper raises significant analytic, interpretive, and representational issues. We highlight that report writing is an important, but infrequently discussed, part of research design. We discuss the challenges of supporting the learning and teaching that arises from adopting a socio-cultural lens and argue that such a perspective importantly captures the complex range of issues that work-based practitioners have to grapple with. This offers a challenge to how we research and seek to influence work-based learning and teaching in health care settings.

Optimal timing in biological processes

USGS Publications Warehouse

Williams, B.K.; Nichols, J.D.

1984-01-01

A general approach for obtaining solutions to a class of biological optimization problems is provided. The general problem is one of determining the appropriate time to take some action, when the action can be taken only once during some finite time frame. The approach can also be extended to cover a number of other problems involving animal choice (e.g., mate selection, habitat selection). Returns (assumed to index fitness) are treated as random variables with time-specific distributions, and can be either observable or unobservable at the time action is taken. In the case of unobservable returns, the organism is assumed to base decisions on some ancillary variable that is associated with returns. Optimal policies are derived for both situations and their properties are discussed. Various extensions are also considered, including objective functions based on functions of returns other than the mean, nonmonotonic relationships between the observable variable and returns; possible death of the organism before action is taken; and discounting of future returns. A general feature of the optimal solutions for many of these problems is that an organism should be very selective (i.e., should act only when returns or expected returns are relatively high) at the beginning of the time frame and should become less and less selective as time progresses. An example of the application of optimal timing to a problem involving the timing of bird migration is discussed, and a number of other examples for which the approach is applicable are described.

Cassini observations of flow-like features in western Tui Regio, Titan

USGS Publications Warehouse

Barnes, J.W.; Brown, R.H.; Radebaugh, J.; Buratti, B.J.; Sotin, Christophe; Le, Mouelic S.; Rodriguez, S.; Turtle, E.P.; Perry, J.; Clark, R.; Baines, K.H.; Nicholson, P.D.

2006-01-01

A large (>3 ?? 104 km2), lobate, 5-??m-bright region seen by Cassini on Titan's leading equatorial region is best explained as a flow field. We discuss observations from the Visual and Infrared Mapping Spectrometer and Imaging Science Subsystem of the feature and present a map of the field. We establish relative ages of flow features and discuss possible formation mechanisms and the implications of this finding for the evolution of Titan's surface. Copyright 2006 by the American Geophysical Union.

49 CFR 37.161 - Maintenance of accessible features: General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Maintenance of accessible features: General. 37.161 Section 37.161 Transportation Office of the Secretary of Transportation TRANSPORTATION SERVICES FOR INDIVIDUALS WITH DISABILITIES (ADA) Provision of Service § 37.161 Maintenance of accessible...

Modification of spectral features by nonhuman primates

PubMed Central

Weiss, Daniel J.; Hotchkin, Cara F.; Parks, Susan E.

2017-01-01

Ackermann et al. discuss the lack of evidence for vocal control in nonhuman primates. We suggest that nonhuman primates may be capable of achieving greater vocal control than previously supposed. In support of this assertion, we discuss new evidence that nonhuman primates are capable of modifying spectral features in their vocalizations. PMID:25514964

Linguistic Features of Pidgin Arabic in Kuwait

ERIC Educational Resources Information Center

Salem, Ashraf Atta M. S.

2013-01-01

This paper sheds the light on Asian pidgin Arabic, particularly linguistic features of pidgin Arabic in Kuwait. The phonology, syntax and lexicon of the language are described on the basis of interviews conducted with forty Asian informants. The data are discussed in its relation to other studies. Also, the researcher discussed the implication of…

Cluster analysis based on dimensional information with applications to feature selection and classification

NASA Technical Reports Server (NTRS)

Eigen, D. J.; Fromm, F. R.; Northouse, R. A.

1974-01-01

A new clustering algorithm is presented that is based on dimensional information. The algorithm includes an inherent feature selection criterion, which is discussed. Further, a heuristic method for choosing the proper number of intervals for a frequency distribution histogram, a feature necessary for the algorithm, is presented. The algorithm, although usable as a stand-alone clustering technique, is then utilized as a global approximator. Local clustering techniques and configuration of a global-local scheme are discussed, and finally the complete global-local and feature selector configuration is shown in application to a real-time adaptive classification scheme for the analysis of remote sensed multispectral scanner data.

A Proposal for a Dimensional Classification System Based on the Shared Features of the DSM-IV Anxiety and Mood Disorders: Implications for Assessment and Treatment

PubMed Central

Brown, Timothy A.; Barlow, David H.

2010-01-01

A wealth of evidence attests to the extensive current and lifetime diagnostic comorbidity of the DSM-IV anxiety and mood disorders. Research has shown that the considerable cross-sectional covariation of DSM-IV emotional disorders is accounted for by common higher-order dimensions such as neuroticism/behavioral inhibition (N/BI) and low positive affect/behavioral activation. Longitudinal studies have indicated that the temporal covariation of these disorders can be explained by changes in N/BI and in some cases, initial levels of N/BI are predictive of the temporal course of emotional disorders. Moreover, the marked phenotypal overlap of the DSM-IV anxiety and mood disorder constructs is a frequent source of diagnostic unreliability (e.g., temporal overlap in the shared features of generalized anxiety disorder and mood disorders, situation specificity of panic attacks in panic disorder and specific phobia). Although dimensional approaches have been considered as a method to address the drawbacks associated with the extant prototypical nosology (e.g., inadequate assessment of individual differences in disorder severity), these proposals do not reconcile key problems in current classification such as modest reliability and high comorbidity. The current paper considers an alternative approach that emphasizes empirically supported common dimensions of emotional disorders over disorder-specific criteria sets. The selection and assessment of these dimensions are discussed along with how these methods could be implemented to promote more reliable and valid diagnosis, prognosis, and treatment planning. For instance, the advantages of this classification system are discussed in context of current transdiagnostic treatment protocols that are efficaciously applied to a variety of disorders by targeting their shared features. PMID:19719339

Exposing ecological and economic costs of the research-implementation gap and compromises in decision making.

PubMed

Kareksela, Santtu; Moilanen, Atte; Ristaniemi, Olli; Välivaara, Reima; Kotiaho, Janne S

2018-02-01

The frequently discussed gap between conservation science and practice is manifest in the gap between spatial conservation prioritization plans and their implementation. We analyzed the research-implementation gap of one zoning case by comparing results of a spatial prioritization analysis aimed at avoiding ecological impact of peat mining in a regional zoning process with the final zoning plan. We examined the relatively complex planning process to determine the gaps among research, zoning, and decision making. We quantified the ecological costs of the differing trade-offs between ecological and socioeconomic factors included in the different zoning suggestions by comparing the landscape-level loss of ecological features (species occurrences, habitat area, etc.) between the different solutions for spatial allocation of peat mining. We also discussed with the scientists and planners the reasons for differing zoning suggestions. The implemented plan differed from the scientists suggestion in that its focus was individual ecological features rather than all the ecological features for which there were data; planners and decision makers considered effects of peat mining on areas not included in the prioritization analysis; zoning was not truly seen as a resource-allocation process and not emphasized in general minimizing ecological losses while satisfying economic needs (peat-mining potential); and decision makers based their prioritization of sites on site-level information showing high ecological value and on single legislative factors instead of finding a cost-effective landscape-level solution. We believe that if the zoning and decision-making processes are very complex, then the usefulness of science-based prioritization tools is likely to be reduced. Nevertheless, we found that high-end tools were useful in clearly exposing trade-offs between conservation and resource utilization. © 2017 Society for Conservation Biology.

Colloquium: Non-Markovian dynamics in open quantum systems

NASA Astrophysics Data System (ADS)

Breuer, Heinz-Peter; Laine, Elsi-Mari; Piilo, Jyrki; Vacchini, Bassano

2016-04-01

The dynamical behavior of open quantum systems plays a key role in many applications of quantum mechanics, examples ranging from fundamental problems, such as the environment-induced decay of quantum coherence and relaxation in many-body systems, to applications in condensed matter theory, quantum transport, quantum chemistry, and quantum information. In close analogy to a classical Markovian stochastic process, the interaction of an open quantum system with a noisy environment is often modeled phenomenologically by means of a dynamical semigroup with a corresponding time-independent generator in Lindblad form, which describes a memoryless dynamics of the open system typically leading to an irreversible loss of characteristic quantum features. However, in many applications open systems exhibit pronounced memory effects and a revival of genuine quantum properties such as quantum coherence, correlations, and entanglement. Here recent theoretical results on the rich non-Markovian quantum dynamics of open systems are discussed, paying particular attention to the rigorous mathematical definition, to the physical interpretation and classification, as well as to the quantification of quantum memory effects. The general theory is illustrated by a series of physical examples. The analysis reveals that memory effects of the open system dynamics reflect characteristic features of the environment which opens a new perspective for applications, namely, to exploit a small open system as a quantum probe signifying nontrivial features of the environment it is interacting with. This Colloquium further explores the various physical sources of non-Markovian quantum dynamics, such as structured environmental spectral densities, nonlocal correlations between environmental degrees of freedom, and correlations in the initial system-environment state, in addition to developing schemes for their local detection. Recent experiments addressing the detection, quantification, and control of non-Markovian quantum dynamics are also briefly discussed.

Application and assessment of multiscale bending energy for morphometric characterization of neural cells

NASA Astrophysics Data System (ADS)

Cesar, Roberto Marcondes; Costa, Luciano da Fontoura

1997-05-01

The estimation of the curvature of experimentally obtained curves is an important issue in many applications of image analysis including biophysics, biology, particle physics, and high energy physics. However, the accurate calculation of the curvature of digital contours has proven to be a difficult endeavor, mainly because of the noise and distortions that are always present in sampled signals. Errors ranging from 1% to 1000% have been reported with respect to the application of standard techniques in the estimation of the curvature of circular contours [M. Worring and A. W. M. Smeulders, CVGIP: Im. Understanding, 58, 366 (1993)]. This article explains how diagrams of multiscale bending energy can be easily obtained from curvegrams and used as a robust general feature for morphometric characterization of neural cells. The bending energy is an interesting global feature for shape characterization that expresses the amount of energy needed to transform the specific shape under analysis into its lowest energy state (i.e., a circle). The curvegram, which can be accurately obtained by using digital signal processing techniques (more specifically through the Fourier transform and its inverse, as described in this work), provides multiscale representation of the curvature of digital contours. The estimation of the bending energy from the curvegram is introduced and exemplified with respect to a series of neural cells. The masked high curvature effect is reported and its implications to shape analysis are discussed. It is also discussed and illustrated that, by normalizing the multiscale bending energy with respect to a standard circle of unitary perimeter, this feature becomes an effective means for expressing shape complexity in a way that is invariant to rotation, translation, and scaling, and that is robust to noise and other artifacts implied by image acquisition.