Sample records for discussed including implications

  1. Electrolysis of lunar soil to produce oxygen and metals

    NASA Technical Reports Server (NTRS)

    Colson, Russell O.; Haskin, Larry A.; Keller, R.

    1991-01-01

    The discussion of melt electrolysis consists of three sections. The implications of the chemistry and physics of fluxed and raw melts on melt electrolysis are discussed first. This includes discussion of the factor that influence melt resistivity, melt viscosity, oxygen production efficiency, and the theoretical energy required to produce oxygen. Second, the implications of phase equilibria and solubilities in silicate melts on the selection of materials for container and electrodes are discussed. The implications of proposed container and electrode materials on melt composition and how this effects expected resistivities, viscosities, as outlined in the first section are discussed. Finally, a general discussion of the basic features of both the fluxed and unfluxed melt electrolysis is given, including their advantages and disadvantages and how they compare with alternative processes.

  2. Natural gas in the energy industry of the 21st century

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cuttica, J.

    1995-12-31

    This paper provides a gas industry perspective on the impacts of restructuring the natural gas and electric industries. The four main implications discussed are: (1) market trends, (2) strategic positioning, (3) significant market implications, and (4) issues for the future. Market trends discussed include transitioning rate of return to market competition and regulatory impacts. Significant market implications for gas-fired generation identified include limited new generation investment, extension of existing plants, and an opportunity for distributed power generation. 12 tabs.

  3. The Library and the Pluralistic Campus in the Year 2000: Implications for Administrators.

    ERIC Educational Resources Information Center

    Welch, Janet E.; Lam, R. Errol

    1991-01-01

    Discussion of changing demographics and implications for academic libraries focuses on the expected increases in the numbers of Blacks and international students. Educational trends are discussed; and program ideas for academic libraries preparing for a multicultural environment are suggested, including sensitivity training for staff, minority…

  4. Understanding Bipolar Disorder: Implications for Mental Health Counselors.

    ERIC Educational Resources Information Center

    Withrow, J. Steve; Hinkle, J. Scott

    1990-01-01

    Provides an overview of bipolar disorder, including a discussion of diagnostic indicators, etiological theories, and psychopharmacological treatment. Examines treatment implications for mental health counselors, including role in psychiatric liaison, individual counseling, marriage and family therapy, and vocational counseling. (Author/ABL)

  5. Mechanical stress regulation of plant growth and development

    NASA Technical Reports Server (NTRS)

    Mitchell, C. A.; Myers, P. N.

    1995-01-01

    The authors introduce the chapter with a discussion of lessons from nature, agriculture, and landscapes; terms and definitions; and an historical perspective of mechanical stress regulation of plant growth and development. Topics include developmental responses to mechanical stress; mechanical stress-environment interactions; metabolic, productivity, and compositional changes; hormonal involvement; mechanoperception and early transduction mechanisms; applications in agriculture; and research implications. The discussion of hormonal involvement in mechanical stress physiology includes ethylene, auxin, gibberellins, and other phytohormones. The discussion of applications in agriculture examines windbreaks, nursery practices, height control and conditioning, and enhancement of growth and productivity. Implications for research are related to handling plant materials, space biology, and future research needs.

  6. Atrial Arrhythmias and Their Implications for Space Flight - Introduction

    NASA Technical Reports Server (NTRS)

    Polk, J. D.; Barr, Y. R.; Bauer, P.; Hamilton, D. R.; Kerstman, E.; Tarver, B.

    2010-01-01

    This panel will discuss the implications of atrial arrhythmias in astronauts from a variety of perspectives; including historical data, current practices, and future challenges for exploration class missions. The panelists will present case histories, outline the evolution of current NASA medical standards for atrial arrhythmias, discuss the use of predictive tools, and consider potential challenges for current and future missions.

  7. Emerging Concept of Giftedness: The Implementation of Gifted Education in Nigeria.

    ERIC Educational Resources Information Center

    Adesokan, E. O.

    1987-01-01

    The present status of gifted education in Nigeria is discussed in terms of the changing perception of giftedness, the learning environment (including home tutoring, acceleration, enrichment, and special classes/schools.) Implications for Nigerian education are discussed including the school statutory age, the mandated curriculum, and educational…

  8. Workplace Democracy: A Review of Literature and Implications for Human Resource Development

    ERIC Educational Resources Information Center

    Hatcher, Tim

    2007-01-01

    A review of workplace democracy revealed that both practice and research need updating. The results are discussed in terms of history, theory, research and practice. Implications for human resource development research and practice are also included. (Contains 2 tables.)

  9. Some Implications of Cognitive Theory for Instructional Design.

    ERIC Educational Resources Information Center

    Winn, William

    1990-01-01

    Examines some of the recent developments in cognitive theory and explores their implications for instructional design. Topics discussed include a shift from emphasis on behavioral theory to cognitive theory; task analysis; instructional objectives; learner characteristics; instructional strategies; metacognition; and the dynamic nature of…

  10. The CHARGE Association: Implications for Teachers.

    ERIC Educational Resources Information Center

    Jones, Thomas W.; Dunne, Michele T.

    1988-01-01

    CHARGE association is described as a diagnostic label for a group of congenital malformations, including coloboma, heart defects, atresia choanae, retarded postnatal growth/central nervous system defects, genital hypoplasia, and ear deformities. Etiology and characteristics of the CHARGE association are discussed, along with implications for…

  11. Unconventional eating practices and their health implications.

    PubMed

    Hanning, R M; Zlotkin, S H

    1985-04-01

    The authors discuss a number of unconventional or faddist foods and eating practices and their health implications. Among the topics included are vegetarianism, Zen macrobiotic diets, fast foods, junk foods, megavitamins and their toxicity, health foods, fad diets in infancy, and elimination diets.

  12. The 1997 IDEA Amendments: Implications for School Principals.

    ERIC Educational Resources Information Center

    Williams, Brenda T.; Katsiyannis, Antonis

    1998-01-01

    Discusses implications of the 1997 Individuals with Disabilities Education Act Amendments for local policy and practice. Secondary principals should understand new requirements for locating and evaluating eligible students with disabilities, including disabled students in state and districtwide assessment programs, involving regular teachers in…

  13. The Reagan Years: Regrouping on Education.

    ERIC Educational Resources Information Center

    Walsh, John

    1980-01-01

    Discusses implications for the Department of Education with the election of Ronald Reagan to the presidency. The future of the National Education Association (NEA) is also discussed, including its hopes for general aid to education and federal collective bargaining laws. Revision of higher education programs is also discussed. (CS)

  14. The Talent Search Model: Implications for Secondary School Reform.

    ERIC Educational Resources Information Center

    VanTassel-Baska, Joyce

    1985-01-01

    The Midwest Talent Search Project is an effort to identify and provide an appropriate accelerated curriculum for gifted secondary school students in the midwest. Many aspects of the project are discussed here, including testing, programming, benefits, and implications for curriculum reform. (Author/MCG)

  15. Customer Service: Implications for Reference Practice.

    ERIC Educational Resources Information Center

    Whitlatch, Jo Bell

    1995-01-01

    The past decade has seen an increasing emphasis on customer service in business research and management. Two concepts in understanding business customer service practices are discussed: the service encounter and total quality management. Highlights include customer service research and practices in business; implications for library reference…

  16. Issues in the Management of Distance Education.

    ERIC Educational Resources Information Center

    Murgatroyd, Stephen; Woudstra, Andrew

    1989-01-01

    Examines key issues facing administrators at Athabasca University and discusses their implications for distance education organizations. Topics discussed include strategic planning; accountability and cost effectiveness; consortia and cooperation; instructional design; managing technological innovation; marketing; quality assurance; and…

  17. Institutional Image: The Concept and Implications for Administrative Action.

    ERIC Educational Resources Information Center

    Renihan, Frederick I; Renihan, Patrick J.

    1989-01-01

    Explores institutional image as a key to providing a philosophy and a logical foundation for school improvement efforts. Identifies two image dimensions (cosmetic and pastoral) and classifies five school types (synergistic, candy store, disaffected, monastic, and survivor), and discusses implications for administrative action. Includes three…

  18. Sexuality and Aging: An Overview for Counselors.

    ERIC Educational Resources Information Center

    Capuzzi, Dave

    1982-01-01

    Discusses male and female sexual response in aging adults. Describes common medical problems and their relationship to sexuality in older adults. Considers common surgeries including hysterectomy, mastectomy, and prostatectomy and sexuality in older adults. Discusses implications for counselors. (RC)

  19. Expert Systems: Tutors, Tools, and Tutees.

    ERIC Educational Resources Information Center

    Lippert, Renate C.

    1989-01-01

    Discusses the current status, research, and practical implications of artificial intelligence and expert systems in education. Topics discussed include computer-assisted instruction; intelligent computer-assisted instruction; intelligent tutoring systems; instructional strategies involving the creation of knowledge bases; decision aids;…

  20. Enhanced/Synthetic Vision Systems - Human factors research and implications for future systems

    NASA Technical Reports Server (NTRS)

    Foyle, David C.; Ahumada, Albert J.; Larimer, James; Sweet, Barbara T.

    1992-01-01

    This paper reviews recent human factors research studies conducted in the Aerospace Human Factors Research Division at NASA Ames Research Center related to the development and usage of Enhanced or Synthetic Vision Systems. Research discussed includes studies of field of view (FOV), representational differences of infrared (IR) imagery, head-up display (HUD) symbology, HUD advanced concept designs, sensor fusion, and sensor/database fusion and evaluation. Implications for the design and usage of Enhanced or Synthetic Vision Systems are discussed.

  1. "The Dyslogic Syndrome": Some Improbable Implications to Teacher Education.

    ERIC Educational Resources Information Center

    Peterson, Daniel L.

    The author traces developments in the education of children with learning disabilities and comments on implications for teacher education. He suggests that a critical neglect of the study of cognition exists. The cognitive orientation, which includes emphases on active participation, student responsibility and long-term acquisitions, is discussed,…

  2. Academic Entrepreneurship (Re)defined: Significance and Implications for the Scholarship of Higher Education

    ERIC Educational Resources Information Center

    Mars, Matthew M.; Rios-Aguilar, Cecilia

    2010-01-01

    Over the past several decades higher education scholars have conducted a significant amount of research aimed at understanding the implications of enhanced interactions between the academy and the private marketplace. Accordingly, a voluminous literature that includes conceptualizations and discussions of "academic entrepreneurship" has emerged.…

  3. An Exploration of Child Maltreatment among Homeless Families: Implications for Family Policy

    ERIC Educational Resources Information Center

    Pardeck, John T.

    2005-01-01

    This research explores the incidence of child maltreatment among homeless families. The maltreatment explored in the study includes physical, emotional and sexual abuse. The data reported a high incidence of child maltreatment in the lives of the homeless. The policy implications for these findings are discussed.

  4. Beta-Blockers and the Kidney: Implications for Renal Function and Renin Release.

    ERIC Educational Resources Information Center

    Epstein, Murray; And Others

    1985-01-01

    Reviews and discusses current information on the human renal response as related to beta-blockers (antihypertension agents). Topic areas considered include cardioselectivity, renal hemodynamics, systemic hemodynamics, changes with acute and chronic administration, influence of dose, and others. Implications and an 11-item multiple-choice self-quiz…

  5. The "Blur" of Federal Information and Services: Implications for University Libraries.

    ERIC Educational Resources Information Center

    Lippincott, Joan K.; Cheverie, Joan F.

    1999-01-01

    Discusses the interrelation of product content with associated services, or "blurring" (Davis and Meyer) and its relation to federal information and services. Highlights include the federal role in facilitating use of government-collected information; infrastructure and policy issues; and implications for university library reference services,…

  6. Social Implications of Biological Education.

    ERIC Educational Resources Information Center

    Grobman, Arnold B.

    Political and social implications of biological research, with particular reference to consequences for education, are discussed in this collection of papers presented at the 1969 convention of the National Association of Biology Teachers. Commentary papers by a panel of three, including at least one high school biology teacher and one expert in…

  7. The Homeless in the Public Library: Implications for Access to Libraries.

    ERIC Educational Resources Information Center

    Simmons, Randall C.

    1985-01-01

    Discussion of the homeless in American public libraries focuses on harmless individuals who may be considered nuisance by library staff/patrons. Highlights include literature about problem library patrons, national problem, social issues, major themes (offense to others and library staff, balancing rights, and elitism), and implications for…

  8. Publishing and the Book Trade in Sub-Saharan Africa: Trends and Issues and Their Implications for American Libraries.

    ERIC Educational Resources Information Center

    Bischof, Phyllis B.

    1991-01-01

    Discusses developments in publishing in Sub-Saharan Africa and suggests implications for American libraries. Highlights include economic constraints; state-sponsored publishing; African authors; publishing in Nigeria and South Africa; publishing for children; religious publishing houses; multinational firms; cooperative efforts that offer…

  9. How Teenagers Cope with Sibling Death: Some Implications for School Counselors.

    ERIC Educational Resources Information Center

    Balk, David

    1983-01-01

    Investigated the reactions of 33 adolescents to the death of a sibling, using private interviews. Emotions reported included shock, confusion, numbness, depression, and anger. For most respondents study habits became worse. Many peers were portrayed as uncertain and uncomfortable. Implications for school counselors are discussed. (JAC)

  10. Decision-Making Theory Applied to Architectural Programming: Some Research Implications.

    ERIC Educational Resources Information Center

    Green, Meg

    The implications of delineating and determining the sequence of programming decisions are shown in the selection of building committee membership. The role relationships of client and architect are discussed in terms of decision-making function. Decision tables are described as aids in problem analysis. Other topics include information and…

  11. Assessment of Health Knowledge in College Women.

    ERIC Educational Resources Information Center

    Richmond, Gail; And Others

    1991-01-01

    The level of accurate health knowledge that young adult women possess regarding selected information dealing with nutrition; disease; and over-the-counter, prescription, and social drugs is discussed. Sections include the introduction, methods, results, discussion, and implications for biology teachers. (KR)

  12. An Information Processing View of Field Dependence-Independence.

    ERIC Educational Resources Information Center

    Davis, J. Kent; Cochran, Kathryn F.

    1989-01-01

    Discusses field dependence-independence from an information processing perspective. Topics discussed include field dependence theory, stages of information processing, developmental issues and implications, and future directions. The information reviewed indicates that field-independent individuals are more efficient than field-dependent…

  13. Implications of the behavioural immune system for social behaviour and human health in the modern world.

    PubMed

    Schaller, Mark; Murray, Damian R; Bangerter, Adrian

    2015-05-26

    The 'behavioural immune system' is composed of mechanisms that evolved as a means of facilitating behaviours that minimized infection risk and enhanced fitness. Recent empirical research on human populations suggests that these mechanisms have unique consequences for many aspects of human sociality--including sexual attitudes, gregariousness, xenophobia, conformity to majority opinion and conservative sociopolitical attitudes. Throughout much of human evolutionary history, these consequences may have had beneficial health implications; but health implications in modern human societies remain unclear. This article summarizes pertinent ways in which modern human societies are similar to and different from the ecologies within which the behavioural immune system evolved. By attending to these similarities and differences, we identify a set of plausible implications-both positive and negative-that the behavioural immune system may have on health outcomes in contemporary human contexts. We discuss both individual-level infection risk and population-level epidemiological outcomes. We also discuss a variety of additional implications, including compliance with public health policies, the adoption of novel therapeutic interventions and actual immunological functioning. Research on the behavioural immune system, and its implications in contemporary human societies, can provide unique insights into relationships between fitness, sociality and health. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  14. The Americans with Disabilities Act: Implications for Camp Programming.

    ERIC Educational Resources Information Center

    Bedini, Leandra A.; And Others

    1992-01-01

    Discusses the effect of the Americans with Disabilities Act (ADA) on camp programing and provides strategies to improve camp accessibility for people with disabilities. Discusses obstacles to integrated programing including ecological and architectural barriers, attitudinal barriers, transportation barriers, barriers of omission, economic…

  15. Cervical Cancer, A Major Killer of Hispanic Women: Implications for Health Education.

    ERIC Educational Resources Information Center

    Morris, Donna LeBlanc; And Others

    1989-01-01

    This article outlines the incidence and etiology of cervical cancer among Hispanic women, discusses screening and treatment, and identifies factors that may contribute to high incidence and death rate. Factors include Hispanics' utilization of health services, culturally based attitudes, and the role of Hispanic men. Implications for health…

  16. From Metacognition to Whole Language: The Spectrum of Literacy in Elementary School Science.

    ERIC Educational Resources Information Center

    Balajthy, Ernest

    This paper considers the integration of reading and writing into elementary science teaching by way of the implications of two leading theories pertaining to literacy: metacognitive theory and whole language theory. Discussion of the implications of metacognition includes attention to the issue of helping to overcome readers' nonscientific…

  17. In Search of Ideal Information Pricing.

    ERIC Educational Resources Information Center

    Hawkins, Donald T.

    1989-01-01

    Reviews some of the models used for pricing online information services and discusses some of the implications of these pricing algorithms. Topics discussed include online versus print pricing; charges for the retrieval process; charges for the retrieved information; telecommunications charges; and the pricing policies of Chemical Abstracts…

  18. Collection Development for the Electronic Library.

    ERIC Educational Resources Information Center

    Herzog, Kate

    1990-01-01

    Summarizes issues discussed at an institute held at Cornell University on the impact of electronic publishing on library collection development. Topics discussed include libraries of the future; the National Research and Education Network (NREN); a definition of an electronic library; scholarly communication; implications of national networks; and…

  19. How College Affects Student Athletes.

    ERIC Educational Resources Information Center

    Howard-Hamilton, Mary F.; Sina, Julie A.

    2001-01-01

    Discusses how college affects student athletes. Research cited includes studies using theories of student development and results from the National Study on Student Learning that describe the desired outcomes of college for student athletes. Discusses implications for policies and practices that address the critical needs of student athletes.…

  20. Post Traumatic Stress Disorder: Implications for Seasonal Lifeguards.

    ERIC Educational Resources Information Center

    Grosse, Susan J.

    2001-01-01

    Discusses the importance of including information on posttraumatic stress disorder (PTSD) in preseason and inservice training for lifeguards as well as critical information on stress management. The article defines PTSD; examines lifeguard-related causes of PTSD; discusses the recognition, treatment, and prevention of PTSD; and notes implications…

  1. Controlling Urban Air Pollution: A Benefit-Cost Assessment.

    ERIC Educational Resources Information Center

    Krupnick, Alan J.; Portney, Paul R.

    1991-01-01

    The pros and cons of air pollution control efforts are discussed. Both national and regional air pollution control plans are described. Topics of discussion include benefit-cost analysis, air quality regulation, reducing ozone in the urban areas, the Los Angeles plan, uncertainties, and policy implications. (KR)

  2. Caught in the Act: How Extraverted and Introverted Friends Communally Cope with Being Recorded.

    PubMed

    Thorne, Avril; Shapiro, Lauren; Cardilla, Kim; Korobov, Neill; Nelson, Paul A

    2009-08-01

    This study explored how close friends who were similar or opposite on extraversion communally coped with being put on the spot to produce a recorded conversation. Participants were 50 pairs of same-sex college-age friends (54% female) who explicitly discussed the fact that their conversation was being recorded. The initial 'on-stage' episode emerged consistently earliest for extraverted dyads, and the majority of their episodes quickly diverted the on-stage moment. Dyads that included at least one introvert engaged in more extensive assortments of on-stage maneuvers, including research talk, soothing, and joking. In introvert-extravert dyads the extravert usually initiated and ended these episodes. Implications are discussed for understanding how personality is reciprocally implicated in managing shared everyday problems.

  3. Who's Gonna Pay the Piper for Free Online Databases?

    ERIC Educational Resources Information Center

    Jacso, Peter

    1996-01-01

    Discusses new pricing models for some online services and considers the possibilities for the traditional online database market. Topics include multimedia music databases, including copyright implications; other retail-oriented databases; and paying for free databases with advertising. (LRW)

  4. Skin Color in Transracial and Inracial Adoptive Placements: Implications for Special Needs Adoptions.

    ERIC Educational Resources Information Center

    McRoy, Ruth G.; Grape, Helen

    1999-01-01

    Explores interview excerpts of African-American adults adopted either transracially or interracially to discuss implications of color for special-needs adoptions. Finds that the issue of color extends beyond racial differences to include skin tone and that children are aware of and internalize color at an early age. Suggests that adoption agencies…

  5. What are the implications of the Institute of Medicine report "The future of nursing: leading change, advancing health" for school nursing practice?

    PubMed

    Sheetz, Anne H

    2012-11-01

    In 2010, the Robert Wood Johnson Foundation Initiative at the Institute of Medicine issued a comprehensive report entitled, "The future of nursing: leading change, advancing health." The following is a synopsis of the report, including excerpts, recommendations, and a discussion of school nursing implications.

  6. Technology Changes Intelligence: Societal Implications and Soaring IQs.

    ERIC Educational Resources Information Center

    Sternberg, Robert J.

    1997-01-01

    Discusses the effects technology may have on human intelligence. Topics include the use of computational devices, including calculators, in schools; the changes word processing has brought about in writing; the use of television; and the effects of weapons on children. (LRW)

  7. Possible Neurolinguistic Breakdown in Autistic Children.

    ERIC Educational Resources Information Center

    Wetherby, Amy Miller

    1984-01-01

    The article reviews research on direct and indirect evidence of neurological dysfunction associated with autism (including brainstem and cortical dysfunction). Issues of reorganization of language functions are discussed. Clinical implications of findings, including the value of gestural sign systems, are noted. (CL)

  8. Monte Carlo Techniques for Calculations of Charge Deposition and Displacement Damage from Protons in Visible and Infrared Sensor Arrays

    NASA Technical Reports Server (NTRS)

    Marshall, Paul; Reed, Robert; Fodness, Bryan; Jordan, Tom; Pickel, Jim; Xapsos, Michael; Burke, Ed

    2004-01-01

    This slide presentation examines motivation for Monte Carlo methods, charge deposition in sensor arrays, displacement damage calculations, and future work. The discussion of charge deposition sensor arrays includes Si active pixel sensor APS arrays and LWIR HgCdTe FPAs. The discussion of displacement damage calculations includes nonionizing energy loss (NIEL), HgCdTe NIEL calculation results including variance, and implications for damage in HgCdTe detector arrays.

  9. Ethical Challenges in Infant Feeding Research

    PubMed Central

    Binns, Colin; Lee, Mi Kyung; Kagawa, Masaharu

    2017-01-01

    Infants have a complex set of nutrient requirements to meet the demands of their high metabolic rate, growth, and immunological and cognitive development. Infant nutrition lays the foundation for health throughout life. While infant feeding research is essential, it must be conducted to the highest ethical standards. The objective of this paper is to discuss the implications of developments in infant nutrition for the ethics of infant feeding research and the implications for obtaining informed consent. A search was undertaken of the papers in the medical literature using the PubMed, Science Direct, Web of Knowledge, Proquest, and CINAHL databases. From a total of 9303 papers identified, the full text of 87 articles that contained discussion of issues in consent in infant feeding trials were obtained and read and after further screening 42 papers were included in the results and discussion. Recent developments in infant nutrition of significance to ethics assessment include the improved survival of low birth weight infants, increasing evidence of the value of breastfeeding and evidence of the lifelong importance of infant feeding and development in the first 1000 days of life in chronic disease epidemiology. Informed consent is a difficult issue, but should always include information on the value of preserving breastfeeding options. Project monitoring should be cognisant of the long term implications of growth rates and early life nutrition. PMID:28085057

  10. Conscious Connections: Phenomenology and Decoding the Disciplines

    ERIC Educational Resources Information Center

    Currie, Genevieve

    2017-01-01

    This chapter describes how seven disciplinary bottlenecks from four diverse disciplines were analyzed using a phenomenological perspective and includes a discussion of embodied knowing and implications for educators.

  11. Job Enrichment: Evaluation with Implications for Air Force Job Redesign. Interim Report, 1 January 1975-30 April 1977.

    ERIC Educational Resources Information Center

    Watson, Thomas W.; Zumbro, Patrick A.

    The main text of this report consists of a review and evaluation of job enrichment as an approach to job redesign, with implications for Air Force research and application. In addition, two appendixes are included: the first, a supplemental historical discussion; the second, a ninety-six-item annotated bibliography. Specific objectives are to…

  12. Chiari Type I Malformations in Young Adults: Implications for the College Health Practitioner

    ERIC Educational Resources Information Center

    Elam, Mary Jane; Vaughn, John A.

    2011-01-01

    In this article, the authors describe 2 cases of Chiari type I malformation (CM-I) in students presenting to a college health center within a 6-month period. A review of CM-I, including epidemiology, typical presentation, evaluation, and management, is followed by a discussion of the clinical and functional implications of the disorder in an…

  13. Implications of Peer Pressure for Adolescent Nursing Research: A Concept Analysis Approach.

    PubMed

    Pittman, Alison F

    2018-01-02

    The influence of peers is widely held as a significant factor in child and adolescent development. As health care providers seek ways to improve the health of children and adolescents, peer pressure must be examined. This article analyzes peer pressure and its relationship to the health of children and adolescents. Defining attributes of peer pressure are discussed, including incomplete identity formation, the presence of a peer influence, and a need for approval. Antecedents and consequences of peer pressure are also explored. Methods of measuring peer pressure are discussed, along with implications for health care research in the pediatric population.

  14. After the Fireworks: Opportunities and Directions for University Libraries.

    ERIC Educational Resources Information Center

    Byrne, Alex

    This paper discusses developments in information and communications technologies and their impact on university libraries. Topics addressed include: (1) background, including the Information Revolution, the Knowledge Economy, implications for education and information services, and responses to the challenges of globalization; (2) university…

  15. A Feminist Paradigm for Library and Information Science.

    ERIC Educational Resources Information Center

    Hannigan, Jane Anne; Crew, Hilary

    1993-01-01

    Discussion of feminist scholarship and feminist thinking focuses on feminism in librarianship. Topics addressed include research methodologies; implications for library and information science; a feminist model, including constructed knowledge; standpoint theory; benefits of feminist scholarship; and a library model. (Contains 14 references.) (LRW)

  16. Caught in the Act: How Extraverted and Introverted Friends Communally Cope with Being Recorded

    PubMed Central

    Thorne, Avril; Shapiro, Lauren; Cardilla, Kim; Korobov, Neill; Nelson, Paul A.

    2009-01-01

    This study explored how close friends who were similar or opposite on extraversion communally coped with being put on the spot to produce a recorded conversation. Participants were 50 pairs of same-sex college-age friends (54% female) who explicitly discussed the fact that their conversation was being recorded. The initial 'on-stage' episode emerged consistently earliest for extraverted dyads, and the majority of their episodes quickly diverted the on-stage moment. Dyads that included at least one introvert engaged in more extensive assortments of on-stage maneuvers, including research talk, soothing, and joking. In introvert-extravert dyads the extravert usually initiated and ended these episodes. Implications are discussed for understanding how personality is reciprocally implicated in managing shared everyday problems. PMID:20161279

  17. The Power of Intelligent Engineering--Or, How Advertising Teaches Us to Learn.

    ERIC Educational Resources Information Center

    Roberts, Richard

    1994-01-01

    Discusses how advertisers use information (i.e., how they organize and present words) and suggests similarities with educators who try to attract attention, impart information, and foster retention of that information. Positioning in marketing is explained; and educational implications are discussed, including focusing on the audience and studying…

  18. The Status of Technology-Enhanced Education and Service Delivery in Rehabilitation Counselor Education

    ERIC Educational Resources Information Center

    Oswald, Gina R.; Huber, Mary J.; Wilson, Josephine F.; Embree, Jared

    2015-01-01

    Purpose: The purpose of this article is to discuss the upsurge of technology-enhanced rehabilitation education programs and telerehabilitation services, to provide examples of these advancements, and to discuss the implications of this technology for education and the field including the unique advantage to developing technological skills through…

  19. MIPPA: First Broad Changes to Medicare Part D Plan Operations.

    PubMed

    LeMasurier, Jean D; Edgar, Babette

    2009-04-01

    In July 2008, as part of broad Medicare reform, Congress passed the first major legislative changes to Medicare Part D since its enactment in 2003-the Medicare Improvements for Patients and Providers Act. This new legislation has significant implications for how Part D plans can market and enroll Medicare beneficiaries. The new legislation also strengthened beneficiary protections, expanded the low-income subsidy provisions originally included in Part D, and expanded Part D coverage. These changes have significant implications for the operation of Part D plans and can affect those involved in benefit design, including specialty pharmacy coverage. This article discusses the major changes that took effect on January 1, 2009, and have immediate implications for Part D plan sponsors, including Medicare Advantage plans and stand-alone prescription drug plans.

  20. MIPPA: First Broad Changes to Medicare Part D Plan Operations

    PubMed Central

    LeMasurier, Jean D.; Edgar, Babette

    2009-01-01

    In July 2008, as part of broad Medicare reform, Congress passed the first major legislative changes to Medicare Part D since its enactment in 2003—the Medicare Improvements for Patients and Providers Act. This new legislation has significant implications for how Part D plans can market and enroll Medicare beneficiaries. The new legislation also strengthened beneficiary protections, expanded the low-income subsidy provisions originally included in Part D, and expanded Part D coverage. These changes have significant implications for the operation of Part D plans and can affect those involved in benefit design, including specialty pharmacy coverage. This article discusses the major changes that took effect on January 1, 2009, and have immediate implications for Part D plan sponsors, including Medicare Advantage plans and stand-alone prescription drug plans. PMID:25126279

  1. Effects of New Technologies.

    ERIC Educational Resources Information Center

    Social and Labour Bulletin, 1980

    1980-01-01

    Transnational implications of technological change and innovation in telecommunications are discussed, including impact on jobs and industrial relations, computer security, access to information, and effects of technological innovation on international economic systems. (SK)

  2. Research You Can Use: Marketing to Children.

    ERIC Educational Resources Information Center

    Walter, Virginia A.

    1994-01-01

    Examines marketing literature for profit-oriented organizations and discusses how those principles can be applied to public library services for children. Topics addressed include children as a source of revenue; market research; product development; promotion; retailing; and implications for public libraries, including population trends and…

  3. Supercalculators and the Curriculum.

    ERIC Educational Resources Information Center

    Shumway, Richard

    1990-01-01

    Discussed are supercalculator capabilities and possible teaching implications. Included are six examples that use a supercalculator for topics that include volume, graphing, algebra, polynomials, matrices, and elementary calculus. A short review of the research on supercomputers in education and the impact they could have on the curriculum is…

  4. Knowledge as an Asset--A View from Industry.

    ERIC Educational Resources Information Center

    Thomas, Grant

    1992-01-01

    Discusses issues related to the value of knowledge to corporations, including technological change, increased competition, and global complexity. Implications for training programs and educational institutions are considered, and a strategic knowledge plan that includes four fields of activity is presented: corporate knowledge engineering,…

  5. Probiotics, prebiotics, and the host microbiome: the science of translation

    PubMed Central

    Petschow, Bryon; Doré, Joël; Hibberd, Patricia; Dinan, Timothy; Reid, Gregor; Blaser, Martin; Cani, Patrice D; Degnan, Fred H; Foster, Jane; Gibson, Glenn; Hutton, John; Klaenhammer, Todd R; Ley, Ruth; Nieuwdorp, Max; Pot, Bruno; Relman, David; Serazin, Andrew; Sanders, Mary Ellen

    2013-01-01

    Recent advances in our understanding of the community structure and function of the human microbiome have implications for the potential role of probiotics and prebiotics in promoting human health. A group of experts recently met to review the latest advances in microbiota/microbiome research and discuss the implications for development of probiotics and prebiotics, primarily as they relate to effects mediated via the intestine. The goals of the meeting were to share recent advances in research on the microbiota, microbiome, probiotics, and prebiotics, and to discuss these findings in the contexts of regulatory barriers, evolving healthcare environments, and potential effects on a variety of health topics, including the development of obesity and diabetes; the long-term consequences of exposure to antibiotics early in life to the gastrointestinal (GI) microbiota; lactose intolerance; and the relationship between the GI microbiota and the central nervous system, with implications for depression, cognition, satiety, and mental health for people living in developed and developing countries. This report provides an overview of these discussions. PMID:24266656

  6. Exploring gender and culture with Khmer refugee women: reflections on participatory feminist research.

    PubMed

    Thompson, J L

    1991-03-01

    This article discusses the process and findings from a study based on the paradigm of feminist participatory research. The research is first discussed in relation to contemporary feminist scholarship. The project combined elements of community health nursing practice and feminist research in a support group with Khmer refugee women. The research explored psychosocial adjustment and the construction of gender among Khmer women. Methods of data collection included life history and trauma history interviews, discussion of dream narratives and Cambodian myths, and participant observation. Findings included four recurring themes identified in the women's stories. The research process is discussed in terms of its implications for nursing praxis.

  7. The Business and Industry Perspective on U.S. Productivity: Implications for Vocational Education. Occasional Paper No. 82.

    ERIC Educational Resources Information Center

    Miller, Thomas W.

    The current lag in U. S. productivity has many implications for vocational education. Before discussing the role of vocational education in easing the productivity crisis, it is necessary to understand the causes of the crisis. Included among these are rising energy prices; the segmentation of the American work force, by both geography and skills;…

  8. Une epreuve orale de francais en fin d'etudes de gestion. Construction et implications pedagogiques (An Oral French Exam at the End of a Marketing Program. Construction and Pedagogical Implications).

    ERIC Educational Resources Information Center

    Crawshaw, Robert H.

    1984-01-01

    An oral language test administered at the end of a four-year program combining business administration and French is described. The test consists of the formal presentation of a report including numbers, graphics, and text, a discussion of a theoretical issue, and interview. (MSE)

  9. The non-motor syndrome of primary dystonia: clinical and pathophysiological implications

    PubMed Central

    Stamelou, Maria; Edwards, Mark J.; Hallett, Mark

    2012-01-01

    Dystonia is typically considered a movement disorder characterized by motor manifestations, primarily involuntary muscle contractions causing twisting movements and abnormal postures. However, growing evidence indicates an important non-motor component to primary dystonia, including abnormalities in sensory and perceptual functions, as well as neuropsychiatric, cognitive and sleep domains. Here, we review this evidence and discuss its clinical and pathophysiological implications. PMID:21933808

  10. Nursing implications of personalized and precision medicine.

    PubMed

    Vorderstrasse, Allison A; Hammer, Marilyn J; Dungan, Jennifer R

    2014-05-01

    Identify and discuss the nursing implications of personalized and precision oncology care. PubMed, CINAHL. The implications in personalized and precision cancer nursing care include interpretation and clinical use of novel and personalized information including genetic testing; patient advocacy and support throughout testing, anticipation of results and treatment; ongoing chronic monitoring; and support for patient decision-making. Attention must also be given to the family and ethical implications of a personalized approach to care. Nurses face increasing challenges and opportunities in communication, support, and advocacy for patients given the availability of advanced testing, care and treatment in personalized and precision medicine. Nursing education and continuing education, clinical decision support, and health systems changes will be necessary to provide personalized multidisciplinary care to patients, in which nurses play a key role. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. The implications of community responses to intimate partner violence in Rwanda

    PubMed Central

    Seyed-Raeisy, Iran; Burgess, Rochelle; Campbell, Catherine

    2018-01-01

    Intimate partner violence (IPV) has significant impacts on mental health. Community-focused interventions have shown promising results for addressing IPV in low-income countries, however, little is known about the implications of these interventions for women’s mental wellbeing. This paper analyses data from a community-focused policy intervention in Rwanda collected in 2013–14, including focus group discussions and in-depth interviews with community members (n = 59). Our findings point to three ways in which these community members responded to IPV: (1) reconciling couples experiencing violence, (2) engaging community support through raising cases of IPV during community discussions, (3) navigating resources for women experiencing IPV, including police, social services and legal support. These community responses support women experiencing violence by helping them access available resources and by engaging in community discussions. However, assistance is largely only offered to married women and responses tend to focus exclusively on physical rather than psychological or emotional forms of violence. Drawing on Campbell and Burgess’s (2012) framework for ‘community mental health competence’, we interrogate the potential implications of these responses for the mental wellbeing of women affected by violence. We conclude by drawing attention to the gendered nature of community responses to IPV and the potential impacts this may have for the mental health of women experiencing IPV. PMID:29718961

  12. The implications of community responses to intimate partner violence in Rwanda.

    PubMed

    Mannell, Jenevieve; Seyed-Raeisy, Iran; Burgess, Rochelle; Campbell, Catherine

    2018-01-01

    Intimate partner violence (IPV) has significant impacts on mental health. Community-focused interventions have shown promising results for addressing IPV in low-income countries, however, little is known about the implications of these interventions for women's mental wellbeing. This paper analyses data from a community-focused policy intervention in Rwanda collected in 2013-14, including focus group discussions and in-depth interviews with community members (n = 59). Our findings point to three ways in which these community members responded to IPV: (1) reconciling couples experiencing violence, (2) engaging community support through raising cases of IPV during community discussions, (3) navigating resources for women experiencing IPV, including police, social services and legal support. These community responses support women experiencing violence by helping them access available resources and by engaging in community discussions. However, assistance is largely only offered to married women and responses tend to focus exclusively on physical rather than psychological or emotional forms of violence. Drawing on Campbell and Burgess's (2012) framework for 'community mental health competence', we interrogate the potential implications of these responses for the mental wellbeing of women affected by violence. We conclude by drawing attention to the gendered nature of community responses to IPV and the potential impacts this may have for the mental health of women experiencing IPV.

  13. Opinion and Special Articles: Loan forgiveness options for young neurologists: Current landscape and practice implications.

    PubMed

    George, Benjamin P; Dorsey, E Ray; Grischkan, Justin A

    2017-04-11

    Increasing education debt has led to the availability of a variety of loan forgiveness options including the Department of Education's Public Service Loan Forgiveness (PSLF) program. This article discusses the current landscape of loan forgiveness options including trends in PSLF for rising neurology trainees, and implications for choices in specialization, employment, practice location, and the pursuit of an academic career. We further provide guidance on how to navigate the various loan forgiveness options that neurology residents and fellows may consider. © 2017 American Academy of Neurology.

  14. Adaptation to Pregnancy: Some Implications for Individual and Family Mental Health.

    ERIC Educational Resources Information Center

    Valentine, Deborah

    1982-01-01

    Discusses pregnancy from four perspectives: as a normative crisis period; as a developmental process including both the pregnant woman and the expectant father; as an experience affecting marital relationships, including the presence of family violence; and as a context for prevention and intervention. (RH)

  15. Demands and Challenges of Being an Educator with a Disability.

    ERIC Educational Resources Information Center

    Obiakor, Festus E.; And Others

    This paper discusses demands and challenges of being an educator with a disability and includes a review of the literature and an analysis of an interview with a leading educator with a disability. The paper opens with a discussion of the definitional issues and implications of the terms "handicap" and "disability." Literature on the role of the…

  16. Adult Education Needs for a Changing State: Discussion Paper on Long-Term Adult Education and Training Needs in California.

    ERIC Educational Resources Information Center

    Best, Fred

    This document was prepared to identify long-term needs and opportunities for adult education, suggesting the implications of long-term social changes without proposing specific actions or institutional arrangements. Following an introduction, chapter 2 discusses the following trends: (1) continued population growth, including the sources and…

  17. Prader-Willi Syndrome: A Review and Implications for Educational Intervention.

    ERIC Educational Resources Information Center

    Scott, Ellen M.; Smith, Tom E. C.; Hendricks, Mary D.; Polloway, Edward A.

    1999-01-01

    This review of Prader-Willi Syndrome notes characteristics (mental retardation and excessive overeating). Educational interventions including weight management, cognitive and educational development, behavioral interventions, and transition to adulthood are discussed. (DB)

  18. The Domain of Developmental Psychopathology.

    ERIC Educational Resources Information Center

    Sroufe, L. Alan; Rutter, Michael

    1984-01-01

    Describes how developmental psychopathology differs from related disciplines, including abnormal psychology, psychiatry, clinical child psychology, and developmental psychology. Points out propositions underlying a developmental perspective and discusses implications for research in developmental psychopathology. (Author/RH)

  19. The Power of Touch: Massage for Infants.

    ERIC Educational Resources Information Center

    Schneider, Elaine Fogel

    1996-01-01

    The potential benefits of massage for infants are discussed, including the role of touch on attachment and bonding and implications of massage for special needs infants. Research results on the benefits of massage for the infant and caregiver are covered, including increased bonding and enhanced growth and development. Historical information on…

  20. Culturally Diverse Literature: Enriching Variety in an Era of Common Core State Standards

    ERIC Educational Resources Information Center

    Boyd, Fenice B.; Causey, Lauren L.; Galda, Lee

    2015-01-01

    The authors argue for the overwhelming importance of finding and including culturally diverse literature into the curricula teachers are authorized to teach. They discuss the implications of use and offer ideas on how to identify quality literature to include in classroom and school libraries.

  1. Perspectives on Privacy and Terrorism: All Is not Lost--Yet.

    ERIC Educational Resources Information Center

    Gellman, Robert

    2002-01-01

    Discusses implications of the U.S.A. Patriot Act, antiterrorism legislation that was passed after the September 11 attacks, regarding privacy issues. Highlights include information privacy; privacy and government, including increases in the surveillance powers of government; privacy and the private sector; and future possibilities. (Author/LRW)

  2. Term Dependence: A Basis for Luhn and Zipf Models.

    ERIC Educational Resources Information Center

    Losee, Robert M.

    2001-01-01

    Discusses relationships between the frequency-based characteristics of neighboring terms in natural language and the rank or frequency of the terms. Topics include information theory measures, including expected mutual information measure (EMIM); entropy and rank; Luhn's model of term aboutness; Zipf's law; and implications for indexing and…

  3. The behavioural immune system and the psychology of human sociality.

    PubMed

    Schaller, Mark

    2011-12-12

    Because immunological defence against pathogens is costly and merely reactive, human anti-pathogen defence is also characterized by proactive behavioural mechanisms that inhibit contact with pathogens in the first place. This behavioural immune system comprises psychological processes that infer infection risk from perceptual cues, and that respond to these perceptual cues through the activation of aversive emotions, cognitions and behavioural impulses. These processes are engaged flexibly, producing context-contingent variation in the nature and magnitude of aversive responses. These processes have important implications for human social cognition and social behaviour-including implications for social gregariousness, person perception, intergroup prejudice, mate preferences, sexual behaviour and conformity. Empirical evidence bearing on these many implications is reviewed and discussed. This review also identifies important directions for future research on the human behavioural immune system--including the need for enquiry into underlying mechanisms, additional behavioural consequences and implications for human health and well-being.

  4. The behavioural immune system and the psychology of human sociality

    PubMed Central

    Schaller, Mark

    2011-01-01

    Because immunological defence against pathogens is costly and merely reactive, human anti-pathogen defence is also characterized by proactive behavioural mechanisms that inhibit contact with pathogens in the first place. This behavioural immune system comprises psychological processes that infer infection risk from perceptual cues, and that respond to these perceptual cues through the activation of aversive emotions, cognitions and behavioural impulses. These processes are engaged flexibly, producing context–contingent variation in the nature and magnitude of aversive responses. These processes have important implications for human social cognition and social behaviour—including implications for social gregariousness, person perception, intergroup prejudice, mate preferences, sexual behaviour and conformity. Empirical evidence bearing on these many implications is reviewed and discussed. This review also identifies important directions for future research on the human behavioural immune system—including the need for enquiry into underlying mechanisms, additional behavioural consequences and implications for human health and well-being. PMID:22042918

  5. Amblyopia and quality of life: a systematic review

    PubMed Central

    Carlton, J; Kaltenthaler, E

    2011-01-01

    Amblyopia is a common condition, which can affect up to 5% of the general population. Health-related quality-of-life (HRQoL) implications of amblyopia and/or its treatment have been explored in the literature. A systematic literature search was undertaken during the period of 7–14 May 2010 to identify the HRQoL implications of amblyopia and/or its treatment. A total of 35 papers were included in the literature review. The HRQoL implications of amblyopia related specifically to amblyopia treatment, rather than to the condition itself. These included impact on family life, social interactions, difficulties in undertaking daily activities, as well as feelings and behaviour. The identified studies adopted a number of methodologies. The study populations included children with the condition, parents of children with amblyopia, and adults who had undertaken amblyopia treatment as a child. Some studies developed their own measures of HRQoL, and others determined HRQoL through proxy measures. The reported findings of the HRQoL implications are of importance when considering the management of cases of amblyopia. The issues identified in the literature review are discussed with respect to how HRQoL is measured (treatment compliance vs proxy measures), and whether HRQoL is taken from a child's or a parent's perspective. Changing societal views over glasses and occlusion therapy are also discussed. Further research is required to assess the immediate and long-term effects of amblyopia and/or its treatment on HRQoL using a more standardised approach. PMID:21274010

  6. Care and Feeding of the Money Tree: Pricing and Financial Aid Strategies and Their Market Implications at Private Colleges and Universities.

    ERIC Educational Resources Information Center

    Zuker, Fred

    2000-01-01

    Considers the dilemma of higher priced college attendance from the viewpoint of private institutions. Identifies and discusses factors currently driving increase in tuition costs and also factors likely to influence relative cost in the next ten years. This discussion includes both increasing and decreasing cost factors. (VWC)

  7. Empathy-related Responding: Associations with Prosocial Behavior, Aggression, and Intergroup Relations

    PubMed Central

    Eisenberg, Nancy; Eggum, Natalie D.; Di Giunta, Laura

    2010-01-01

    Empathy-related responding, including empathy, sympathy, and personal distress, has been implicated in conceptual models and theories about prosocial behavior and altruism, aggression and antisocial behavior, and intergroup relationships. Conceptual arguments and empirical findings related to each of these topics are reviewed. In general, there is evidence that empathy and/or sympathy are important correlates of, and likely contributors to, other-oriented prosocial behavior, the inhibition of aggression and antisocial behavior, and the quality of intergroup relationships. Applied implications of these findings, including preventative studies, are discussed, as are possible future directions. PMID:21221410

  8. Decline in Radiation Hardened Microcircuit Infrastructure

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.

    2015-01-01

    Two areas of radiation hardened microcircuit infrastructure will be discussed: 1) The availability and performance of radiation hardened microcircuits, and, and 2) The access to radiation test facilities primarily for proton single event effects (SEE) testing. Other areas not discussed, but are a concern include: The challenge for maintaining radiation effects tool access for assurance purposes, and, the access to radiation test facilities primarily for heavy ion single event effects (SEE) testing. Status and implications will be discussed for each area.

  9. Policy implications of startup utilization by enrollees in prepaid group plans.

    PubMed

    Baloff, N; Griffith, M J

    1984-04-01

    This article discusses several policy implications of the so-called startup effect, in which high initial health services utilization by new enrollees in prepaid group plans ( PGPs ) becomes reduced with the increasing duration of membership. Results of research in a developing PGP are analyzed as they relate to a mathematical model of startups for two measures of enrollee use. After estimating the total costs of startups in this setting, the motivating effects of such costs on PGPs are examined in relation to several policy issues--including the rate of PGP development in the United States, the use of financial incentives to enroll the elderly and medically disadvantaged, potential inequities of premium determination, the large impact of startups on disenrollment , and the federally mandated process of annual announcement of benefits and open enrollment. Ideas and mechanisms for future study on the startup effect and its policy implications are discussed.

  10. Policy implications of startup utilization by enrollees in prepaid group plans.

    PubMed Central

    Baloff, N; Griffith, M J

    1984-01-01

    This article discusses several policy implications of the so-called startup effect, in which high initial health services utilization by new enrollees in prepaid group plans ( PGPs ) becomes reduced with the increasing duration of membership. Results of research in a developing PGP are analyzed as they relate to a mathematical model of startups for two measures of enrollee use. After estimating the total costs of startups in this setting, the motivating effects of such costs on PGPs are examined in relation to several policy issues--including the rate of PGP development in the United States, the use of financial incentives to enroll the elderly and medically disadvantaged, potential inequities of premium determination, the large impact of startups on disenrollment , and the federally mandated process of annual announcement of benefits and open enrollment. Ideas and mechanisms for future study on the startup effect and its policy implications are discussed. PMID:6724954

  11. Health Implications of the Supreme Court's Obergefell vs. Hodges Marriage Equality Decision

    PubMed Central

    2015-01-01

    Abstract The United States Supreme Court's Obergefell vs. Hodges groundbreaking marriage equality decision also created new terrain for lesbian, gay, bisexual, and transgender (LGBT) persons regarding health, healthcare, and health benefits. This article addresses the health implications of this decision by examining its impact on minority stress and stigmatization and health-related benefits. It also includes a discussion of several impending issues affecting LGBT health that remain after Obergefell. PMID:26788668

  12. The Medicaid personal care services program: implications for social work practice.

    PubMed

    Oktay, J S; Palley, H A

    1991-05-01

    Results of a survey of Medicaid personal care programs in 15 states and the District of Columbia in 1987 show that these programs suffer from many problems. Low wages and slow payment make recruitment and retention of qualified workers difficult. Other problems include lack of coordination among agencies, lack of adequate standards for training or supervision of workers, unequal access to programs, and inequities among states. Implications for social workers are discussed.

  13. Implications of Automotive and Trucking On-Board Information Systems for General Aviation Cockpit Weather Systems

    NASA Technical Reports Server (NTRS)

    Sireli, Yesim; Kauffmann, Paul; Gupta, Surabhi; Kachroo, Pushkin

    2002-01-01

    In this study, current characteristics and future developments of Intelligent Transportation Systems (ITS) in the automobile and trucking industry are investigated to identify the possible implications of such systems for General Aviation (GA) cockpit weather systems. First, ITS are explained based on tracing their historical development in various countries. Then, current systems and the enabling communication technologies are discussed. Finally, a market analysis for GA is included.

  14. Health Implications of the Supreme Court's Obergefell vs. Hodges Marriage Equality Decision.

    PubMed

    Perone, Angela K

    2015-09-01

    The United States Supreme Court's Obergefell vs. Hodges groundbreaking marriage equality decision also created new terrain for lesbian, gay, bisexual, and transgender (LGBT) persons regarding health, healthcare, and health benefits. This article addresses the health implications of this decision by examining its impact on minority stress and stigmatization and health-related benefits. It also includes a discussion of several impending issues affecting LGBT health that remain after Obergefell.

  15. Progress in Early Diagnosis of Sickle Cell Disease

    ERIC Educational Resources Information Center

    Pearson, Howard A.

    1971-01-01

    Discusses the basis of sickle cell Anemia, including: a description of the diseased blood, genetic implications, recognition of symptoms in infancy, the need for implementation of wide screening procedures, and the future prospects of a cure. (AJ)

  16. AIDS and Herpes Carry Weighty Policy Implications for Your Board.

    ERIC Educational Resources Information Center

    McCormick, Kathleen

    1985-01-01

    Few schools have policies to deal specifically with herpes and Acquired Immune Deficiency Syndrome (AIDS). Discusses some schools and states that have developed such policies and includes a source list for more information. (MD)

  17. Television Use by Children and Adolescents.

    ERIC Educational Resources Information Center

    Rubin, Alan M.

    1979-01-01

    Examines the relationships between child and adolescent television use motivations and various sociodemographic characteristics, television viewing levels, program preference, and television attitudes. Viewing motivations include learning, passing time, companionship, escape, arousal, and relaxation. Discusses implications within the conceptual…

  18. Family Selection and Child Care Experiences: Implications for Studies of Child Outcomes.

    ERIC Educational Resources Information Center

    Burchinal, Margaret R.; Nelson, Lauren

    2000-01-01

    Discusses family selection issues that should be considered in child care research, and evidence demonstrating why each should be considered. Issues include whether causal inferences can be made from observational studies and the impact on conclusions from regression analyses that include highly correlated measures of child care experiences,…

  19. E-Books and New Library Service Models: An Analysis of the Impact of E-Book Technology on Academic Libraries.

    ERIC Educational Resources Information Center

    Jantz, Ronald

    2001-01-01

    Analyzes the implications of electronic book technology (e-books) on academic libraries. Discusses new business models for publishers, including self-publishing, Internet publishing, and partnerships with libraries as publishers; impact on library services, including cataloging, circulation, and digital preservation; user benefits; standards;…

  20. Identifying psychotic defenses in a clinical interview.

    PubMed

    Berney, Sylvie; de Roten, Yves; Beretta, Véronique; Kramer, Ueli; Despland, Jean-Nicolas

    2014-05-01

    The Defense Mechanisms Rating Scales (DMRS), one of the most widely used and validated instruments in the study of defense mechanisms, does not include psychotic defenses. The Psychotic-DMRS (P-DMRS) has been developed to include 6 psychotic defense mechanisms: psychotic denial, autistic withdrawal, distortion, delusional projection, fragmentation, and concretization. We discuss psychotic defenses, including the difference between psychotic defenses and psychotic symptoms. Six clinical illustrations demonstrate how the 6 P-DMRS defenses can be identified in patients' narratives selected from the transcripts of dynamic interviews. Implications with respect to patient evaluation and treatment are discussed. © 2014 Wiley Periodicals, Inc.

  1. The New World of Human Genetics: A dialogue between Practitioners & the General Public on Ethical, Legal & Social Implications of the Human Genome Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schofield, Amy

    The history and reasons for launching the Human Genome project and the current uses of genetic human material; Identifying and discussing the major issues stemming directly from genetic research and therapy-including genetic discrimination, medical/ person privacy, allocation of government resources and individual finances, and the effect on the way in which we perceive the value of human life; Discussing the sometimes hidden ethical, social and legislative implications of genetic research and therapy such as informed consent, screening and preservation of genetic materials, efficacy of medical procedures, the role of the government, and equal access to medical coverage.

  2. Integrating molecular and morphological approaches for characterizing parasite cryptic species: implications for parasitology.

    PubMed

    Nadler, Steven A; DE León, Gerardo Pérez-Ponce

    2011-11-01

    Herein we review theoretical and methodological considerations important for finding and delimiting cryptic species of parasites (species that are difficult to recognize using traditional systematic methods). Applications of molecular data in empirical investigations of cryptic species are discussed from an historical perspective, and we evaluate advantages and disadvantages of approaches that have been used to date. Developments concerning the theory and practice of species delimitation are emphasized because theory is critical to interpretation of data. The advantages and disadvantages of different molecular methodologies, including the number and kind of loci, are discussed relative to tree-based approaches for detecting and delimiting cryptic species. We conclude by discussing some implications that cryptic species have for research programmes in parasitology, emphasizing that careful attention to the theory and operational practices involved in finding, delimiting, and describing new species (including cryptic species) is essential, not only for fully characterizing parasite biodiversity and broader aspects of comparative biology such as systematics, evolution, ecology and biogeography, but to applied research efforts that strive to improve development and understanding of epidemiology, diagnostics, control and potential eradication of parasitic diseases.

  3. Simulation in International Relations Education.

    ERIC Educational Resources Information Center

    Starkey, Brigid A.; Blake, Elizabeth L.

    2001-01-01

    Discusses the educational implications of simulations in international relations. Highlights include the development of international relations simulations; the role of technology; the International Communication and Negotiation Simulations (ICONS) project at the University of Maryland; evolving information technology; and simulating real-world…

  4. Research News: Debate on Learning Theory Is Shifting.

    ERIC Educational Resources Information Center

    Fox, Jeffrey L.

    1983-01-01

    Discusses current learning theories, indicating that though many psychologists and ethologists now agree on using a mechanistic approach, some linguists doubt its adequacy. Implications of research on the mollusk "Aplasia" to understand the learning process are included. (JN)

  5. Virtual Reality and Its Potential Application in Education and Training.

    ERIC Educational Resources Information Center

    Milheim, William D.

    1995-01-01

    An overview is provided of current trends in virtual reality research and development, including discussion of hardware, types of virtual reality, and potential problems with virtual reality. Implications for education and training are explored. (Author/JKP)

  6. Toward a Human Architecture: A Sociologist's View of the Profession

    ERIC Educational Resources Information Center

    Gans, Herbert J.

    1978-01-01

    Educational implications for the future role of architecture are discussed, including considerations of architectural training itself, human use of buildings, the economics and politics of building and housing, and training in the aesthetics of popular culture. (LBH)

  7. Acid Rain: Activities for Science Teachers.

    ERIC Educational Resources Information Center

    Johnson, Eric; And Others

    1983-01-01

    Seven complete secondary/college level acid rain activities are provided. Activities include overview; background information and societal implications; major concepts; student objectives; vocabulary/material lists; procedures; instructional strategies; and questions/discussion and extension suggestions. Activities consider effects of acid rain on…

  8. Mission and surface infrastructure concepts

    NASA Technical Reports Server (NTRS)

    Butler, J.; Mcdaniel, S. G.

    1986-01-01

    Several types of manned Mars surface missions, including sorties, fixed-base, and hybrid missions, which can be envisioned as potentially desirable approaches to the exploration and utilization of Mars are identified and discussed. Some of the advantages and disadvantages of each type are discussed briefly. Also, some of the implications of the types of missions on the surface elements' design are discussed briefly. Typical sets of surface elements are identified for each type of mission, and weights are provided for each element and set.

  9. Future Mission Trends and their Implications for the Deep Space Network

    NASA Technical Reports Server (NTRS)

    Abraham, Douglas S.

    2006-01-01

    This viewgraph presentation discusses the direction of future missions and it's significance to the Deep Space Network. The topics include: 1) The Deep Space Network (DSN); 2) Past Missions Driving DSN Evolution; 3) The Changing Mission Paradigm; 4) Assessing Future Mission Needs; 5) Link Support Trends; 6) Downlink Rate Trends; 7) Uplink Rate Trends; 8) End-to-End Link Difficulty Trends; 9) Summary: Future Mission Trend Drivers; and 10) Conclusion: Implications for the DSN.

  10. Policy Implications of Deep Decarbonization in the United States

    NASA Astrophysics Data System (ADS)

    Williams, J.

    2015-12-01

    Independent research teams from sixteen of the largest greenhouse gas (GHG) emitting countries have participated in a collaborative two-year project developing emission reduction scenarios for their own countries consistent with limiting anthropogenic warming to 2 C or less. This talk discusses the policy implications of the work done by the Deep Decarbonization Pathways Project (DDPP) at the US federal and international levels, including new ways of informing decision makers about the requirements of an energy system transformation.

  11. Reconceptualizing cancer immunotherapy based on plant production systems

    PubMed Central

    Hefferon, Kathleen

    2017-01-01

    Plants can be used as inexpensive and facile production platforms for vaccines and other biopharmaceuticals. More recently, plant-based biologics have expanded to include cancer immunotherapy agents. The following review describes the current state of the art for plant-derived strategies to prevent or reduce cancers. The review discusses avenues taken to prevent infection by oncogenic viruses, solid tumors and lymphomas. Strategies including cancer vaccines, monoclonal antibodies and virus nanoparticles are described, and examples are provided. The review ends with a discussion of the implications of plant-based cancer immunotherapy for developing countries. PMID:28884013

  12. Competitive Intelligence and Social Advantage.

    ERIC Educational Resources Information Center

    Davenport, Elisabeth; Cronin, Blaise

    1994-01-01

    Presents an overview of issues concerning civilian competitive intelligence (CI). Topics discussed include competitive advantage in academic and research environments; public domain information and libraries; covert and overt competitive intelligence; data diversity; use of the Internet; cooperative intelligence; and implications for library and…

  13. Educational Systems Design Implications of Electronic Publishing.

    ERIC Educational Resources Information Center

    Romiszowski, Alexander J.

    1994-01-01

    Discussion of electronic publishing focuses on the four main purposes of media in general: communication, entertainment, motivation, and education. Highlights include electronic journals and books; hypertext; user control; computer graphics and animation; electronic games; virtual reality; multimedia; electronic performance support;…

  14. Virtual Reality: Real Promises and False Expectations.

    ERIC Educational Resources Information Center

    Homan, Willem J.

    1994-01-01

    Examines virtual reality (VR), and discusses the dilemma of defining VR, the limitations of the current technology, and the implications of VR for education. Highlights include a VR experience; human factors and the interface; and altered reality versus VR. (Author/AEF)

  15. Traces d'apprentissage (Path of Learning).

    ERIC Educational Resources Information Center

    Allouche, Victor

    1996-01-01

    A French professor teaching in Australia, and learning to cope with the distinctive features of Australian English, reflects on second-language learning processes and their implications for language teaching. Topics discussed include verbal versus nonverbal communication, authentic language situations, cultural context, developing…

  16. Studying Adult Learning through the History of Knowledge.

    ERIC Educational Resources Information Center

    Ekpenyong, Lawrence E.

    1990-01-01

    Discusses the methodology by which people arrive at "knowledge" and how knowledge has been seen by philosophers and critical thinkers through history. Includes the theories of Jurgen Habermas, Jack Mezirow, Thomas Kuhn, and Paulo Freire. Cites implications for adult education. (JOW)

  17. Classification systems in nursing: formalizing nursing knowledge and implications for nursing information systems.

    PubMed

    Goossen, W T; Epping, P J; Abraham, I L

    1996-03-01

    The development of nursing information systems (NIS) is often hampered by the fact that nursing lacks a unified nursing terminology and classification system. Currently there exist various initiatives in this area. We address the question as to how current initiatives in the development of nursing terminology and classification systems can contribute towards the development of NIS. First, the rationale behind the formalization of nursing knowledge is discussed. Next, using a framework for nursing information processing, the most important developments in the field of nursing on formalization, terminology and classification are critically reviewed. The initiatives discussed include nursing terminology projects in several countries, and the International Classification of Nursing Practice. Suggestions for further developments in the area are discussed. Finally, implications for NIS are presented, as well as the relationships of these components to other sections of an integrated computerized patient record.

  18. The changing age distribution in Indonesia and some consequences.

    PubMed

    Nam, C B; Dasvarma, G L; Rahardjo, S P

    1991-08-01

    "Beginning with a discussion of the sources and quality of Indonesian age data by sex, this paper examines the changes in the functional age groups of the population of Indonesia from 1971 to the year 2005, and the implications of these changes for education, labour force participation, dependency ratios and fertility. Data for the period 1971 to 1985 are based on actual enumerations, while those for the period 1990 to 2005 are based on projections. Although the provisional totals of the 1990 Census had been released before the publication of this paper, their breakdown by age was still not available. The functional age categories discussed in the paper include the pre-school years, the primary and intermediate school ages, the teenage years, the reproductive ages of women, the principal working ages and the post-work years. It concludes with a discussion of various policy and planning implications of these changes." excerpt

  19. The CH/π hydrogen bond: Implication in chemistry

    NASA Astrophysics Data System (ADS)

    Nishio, M.

    2012-06-01

    The CH/π hydrogen bond is the weakest extreme of hydrogen bonds that occurs between a soft acid CH and a soft base π-system. Implication in chemistry of the CH/π hydrogen bond includes issues of conformation, crystal packing, and specificity in host/guest complexes. The result obtained by analyzing the Cambridge Structural Database is reviewed. The peculiar axial preference of isopropyl group in α-phellandrene and folded conformation of levopimaric acid have been explained in terms of the CH/π hydrogen bond, by high-level ab initio MO calculations. Implication of the CH/π hydrogen bond in structural biology is also discussed, briefly.

  20. The metaphor of nurse as guest with ethical implications for nursing and healthcare.

    PubMed

    Milton, Constance L

    2005-10-01

    Current healthcare advertising and customer relations terminology acknowledge that healthcare providers, including nurses, are to act as hosts for persons who enter into healthcare agencies and institutions. Indeed, much has been written aligning nursing and other healthcare services with consumer-oriented roles of the hospitality service industry commonly associated with hotels and restaurants. From a human becoming perspective, this article discusses possible ethical, administrative, and practice implications of nurses acting as guests entering into the lives of those we serve.

  1. Strategic Choices for Data Communications Systems.

    ERIC Educational Resources Information Center

    Arns, Robert G.; Urban, Patricia A.

    1984-01-01

    Issues in determining how to develop a data communications system at colleges and universities are discussed including; technical requirements; cost; implications for coordination and (de)centralization of hardware/software; deciding when to create a data network; data security, information integrity, and organizational development. (Author/MLW)

  2. Concurrent Formative Evaluation: Guidelines and Implications for Multimedia Designers.

    ERIC Educational Resources Information Center

    Northrup, Pamela Taylor

    1995-01-01

    Discusses formative evaluation for multimedia instruction and presents guidelines for formatively evaluating multimedia instruction concurrent with analysis, design, and development. Data collection criteria that include group involvement, data collection strategies, and information to be gathered are presented, and rapid prototypes and…

  3. Children Prenatally Exposed to Cocaine and Crack: Implications for Schools.

    ERIC Educational Resources Information Center

    Mullin, Jeff B.

    1992-01-01

    This paper considers the major consequences of prenatal exposure to cocaine, including physiological effects and characteristics of exposed infants and then goes on to discuss the education of these children, noting various behavioral approaches and the importance of assessment. (DB)

  4. What Is A Homosexual? A Definitional Model.

    ERIC Educational Resources Information Center

    Berger, Raymond M.

    1983-01-01

    Presents a definitional model to explain homosexuality and discusses its implications for practice. Contends that social workers must discard the traditional binary model of hetersexual versus homesexual for one incorporating relevant psychosocial factors including life experiences, social reaction, and association with others. (Author/JAC)

  5. Biology and the Individual in Society

    ERIC Educational Resources Information Center

    Manier, Edward

    1970-01-01

    Discusses the interaction of biological knowledge and human values, emphasizing problems raised by man's ability to control human evolution. Analyzes moral and religious concerns about eugenic artificial insemination or nuclear transplantation, including implications for the structure of the family and the basis of parenthood. (EB)

  6. Misconceptions about Psychological Science: A Review

    ERIC Educational Resources Information Center

    Hughes, Sean; Lyddy, Fiona; Lambe, Sinead

    2013-01-01

    This article provides an overview of the available evidence on psychological misconceptions, including key findings, current directions and emerging issues for investigation. We begin by defining misconceptions and then examine their prevalence and persistence, discuss their implications for student learning and highlight potential strategies to…

  7. Copyright, Licensing Agreements and Gateways.

    ERIC Educational Resources Information Center

    Elias, Arthur W.

    1990-01-01

    Discusses technological developments in information distribution and management in relation to concepts of ownership. A historical overview of the concept of copyright is presented; licensing elements for databases are examined; and implications for gateway systems are explored, including ownership, identification of users, and allowable uses of…

  8. Social Security and Part-Time Employment.

    ERIC Educational Resources Information Center

    Euzeby, Alain

    1988-01-01

    Discusses rules governing social security and their implications for part-time employees in various countries. Topics include (1) methods of financing social security, (2) benefits, (3) measures concerning the unemployed, (4) a floor for employers' contributions, (5) graduated contribution rates, and (6) financial incentives. (CH)

  9. Youth at Risk: In Search of a Definition.

    ERIC Educational Resources Information Center

    Tidwell, Romeria; Garrett, Susan Corona

    1994-01-01

    Reviews the definitions of the term "youth at risk" and their perspectives on predisposing conditions. Discusses implications for counseling. Asserts that the sound diagnosis and treatment of adolescents' problems involves careful identification of predisposing conditions and negative outcomes. Includes 16 citations. (Author/CRR)

  10. Preparing Physicians for Practice in Managed Care Environments.

    ERIC Educational Resources Information Center

    Lurie, Nicole

    1996-01-01

    Discussion of managed health care looks at its evolution and characteristics, implications for medical education, and the competencies needed by physicians in this new environment, including epidemiological thinking, understanding of human and organizational behavior, familiarity with information technology, quality control skills, knowledge of…

  11. The Sickening Implications of Globalization.

    ERIC Educational Resources Information Center

    Keigher, Sharon M.; Lowery, Christine T.

    1998-01-01

    "We are all in this together..." begins this review of the threats of globalization. Topics discussed include malnutrition, infectious diseases, urbanization, border protection, poverty, "lifestyle" diseases, the risks of technology, and war. Alternatives to the present trend toward capitalist transformation, possible and practical reforms are…

  12. Implications for Veterinary Medical Education: Paraprofessional Education.

    ERIC Educational Resources Information Center

    Lukens, Roger

    1980-01-01

    The emergence of the veterinary technician as an extension of the veterinarian's capability into animal agriculture is discussed. Some aspects reviewed include: technician education, current restrictions imposed by practice acts, general acceptance by the consumer, and effective relationships for veterinary technicians working under the…

  13. Self-Analysis and Assessment of Entrepreneurial Potential.

    ERIC Educational Resources Information Center

    King, Albert S.

    1985-01-01

    Presents an exercise which is designed to identify behavior characteristics and attitudes and enable individuals to identify and understand personality traits that have essential implications for becoming a successful entrepreneur. Discussion includes the personality traits of the successful entrepreneur and situational factors contributing to…

  14. Biomarkers of PTSD: military applications and considerations.

    PubMed

    Lehrner, Amy; Yehuda, Rachel

    2014-01-01

    Although there are no established biomarkers for posttraumatic stress disorder (PTSD) as yet, biological investigations of PTSD have made progress identifying the pathophysiology of PTSD. Given the biological and clinical complexity of PTSD, it is increasingly unlikely that a single biomarker of disease will be identified. Rather, investigations will more likely identify different biomarkers that indicate the presence of clinically significant PTSD symptoms, associate with risk for PTSD following trauma exposure, and predict or identify recovery. While there has been much interest in PTSD biomarkers, there has been less discussion of their potential clinical applications, and of the social, legal, and ethical implications of such biomarkers. This article will discuss possible applications of PTSD biomarkers, including the social, legal, and ethical implications of such biomarkers, with an emphasis on military applications. Literature on applications of PTSD biomarkers and on potential ethical and legal implications will be reviewed. Biologically informed research findings hold promise for prevention, assessment, treatment planning, and the development of prophylactic and treatment interventions. As with any biological indicator of disorder, there are potentially positive and negative clinical, social, legal, and ethical consequences of using such biomarkers. Potential clinical applications of PTSD biomarkers hold promise for clinicians, patients, and employers. The search for biomarkers of PTSD should occur in tandem with an interdisciplinary discussion regarding the potential implications of applying biological findings in clinical and employment settings.

  15. Probiotics, prebiotics, and the host microbiome: the science of translation.

    PubMed

    Petschow, Bryon; Doré, Joël; Hibberd, Patricia; Dinan, Timothy; Reid, Gregor; Blaser, Martin; Cani, Patrice D; Degnan, Fred H; Foster, Jane; Gibson, Glenn; Hutton, John; Klaenhammer, Todd R; Ley, Ruth; Nieuwdorp, Max; Pot, Bruno; Relman, David; Serazin, Andrew; Sanders, Mary Ellen

    2013-12-01

    Recent advances in our understanding of the community structure and function of the human microbiome have implications for the potential role of probiotics and prebiotics in promoting human health. A group of experts recently met to review the latest advances in microbiota/microbiome research and discuss the implications for development of probiotics and prebiotics, primarily as they relate to effects mediated via the intestine. The goals of the meeting were to share recent advances in research on the microbiota, microbiome, probiotics, and prebiotics, and to discuss these findings in the contexts of regulatory barriers, evolving healthcare environments, and potential effects on a variety of health topics, including the development of obesity and diabetes; the long-term consequences of exposure to antibiotics early in life to the gastrointestinal (GI) microbiota; lactose intolerance; and the relationship between the GI microbiota and the central nervous system, with implications for depression, cognition, satiety, and mental health for people living in developed and developing countries. This report provides an overview of these discussions. © 2013 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals, Inc. on behalf of New York Academy of Sciences.

  16. Leadership networks in Catholic parishes: Implications for implementation research in health

    PubMed Central

    Negrón, Rosalyn; Leyva, Bryan; Allen, Jennifer; Ospino, Hosffman; Tom, Laura; Rustan, Sarah

    2014-01-01

    Through two case studies of Catholic parishes in Massachusetts, this study explores the implications of leader-centered versus distributed leadership in Catholic parishes for the implementation of evidence-based health interventions. The two parishes involved in the study differ from each other in several ways. In the first, parishioners are less engaged in leadership activities at the decision-making level in the parish. A small group of lay volunteers work with the parish priest and other ordained leaders on parish activities. In the second parish, a large and active lay volunteer leadership have forged an organizational structure that allows more independence from the pastor's direct oversight. In this parish, lay volunteer leaders are the prime drivers of organizational programs and events. In 2012–2013, three types of networks were assessed at each parish: discussion, collaboration, and outside-of-parish ties. The contrasts between each parish include differences in density of collaboration, in frequency of discussion, and network centrality of the respective parish priests. We further identified key actors in the network structures at each parish. We discuss the implications of these findings for understanding organizational capacity in the context of health program implementation. PMID:25441317

  17. Leadership networks in Catholic parishes: implications for implementation research in health.

    PubMed

    Negrón, Rosalyn; Leyva, Bryan; Allen, Jennifer; Ospino, Hosffman; Tom, Laura; Rustan, Sarah

    2014-12-01

    Through two case studies of Catholic parishes in Massachusetts, this study explores the implications of leader-centered versus distributed leadership in Catholic parishes for the implementation of evidence-based health interventions. The two parishes involved in the study differ from each other in several ways. In the first, parishioners are less engaged in leadership activities at the decision-making level in the parish. A small group of lay volunteers work with the parish priest and other ordained leaders on parish activities. In the second parish, a large and active lay volunteer leadership have forged an organizational structure that allows more independence from the pastor's direct oversight. In this parish, lay volunteer leaders are the prime drivers of organizational programs and events. In 2012-2013, three types of networks were assessed at each parish: discussion, collaboration, and outside-of-parish ties. The contrasts between each parish include differences in density of collaboration, in frequency of discussion, and network centrality of the respective parish priests. We further identified key actors in the network structures at each parish. We discuss the implications of these findings for understanding organizational capacity in the context of health program implementation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Bacterial Adaptation to Antibiotics through Regulatory RNAs.

    PubMed

    Felden, Brice; Cattoir, Vincent

    2018-05-01

    The extensive use of antibiotics has resulted in a situation where multidrug-resistant pathogens have become a severe menace to human health worldwide. A deeper understanding of the principles used by pathogens to adapt to, respond to, and resist antibiotics would pave the road to the discovery of drugs with novel mechanisms. For bacteria, antibiotics represent clinically relevant stresses that induce protective responses. The recent implication of regulatory RNAs (small RNAs [sRNAs]) in antibiotic response and resistance in several bacterial pathogens suggests that they should be considered innovative drug targets. This minireview discusses sRNA-mediated mechanisms exploited by bacterial pathogens to fight against antibiotics. A critical discussion of the newest findings in the field is provided, with emphasis on the implication of sRNAs in major mechanisms leading to antibiotic resistance, including drug uptake, active drug efflux, drug target modifications, biofilms, cell walls, and lipopolysaccharide (LPS) biosynthesis. Of interest is the lack of knowledge about sRNAs implicated in Gram-positive compared to Gram-negative bacterial resistance. Copyright © 2018 American Society for Microbiology.

  19. A critical review of principal traffic noise models: Strategies and implications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Garg, Naveen, E-mail: ngarg@mail.nplindia.ernet.in; Department of Mechanical, Production and Industrial Engineering, Delhi Technological University, Delhi 110042; Maji, Sagar

    2014-04-01

    The paper presents an exhaustive comparison of principal traffic noise models adopted in recent years in developed nations. The comparison is drawn on the basis of technical attributes including source modelling and sound propagation algorithms. Although the characterization of source in terms of rolling and propulsion noise in conjunction with advanced numerical methods for sound propagation has significantly reduced the uncertainty in traffic noise predictions, the approach followed is quite complex and requires specialized mathematical skills for predictions which is sometimes quite cumbersome for town planners. Also, it is sometimes difficult to follow the best approach when a variety ofmore » solutions have been proposed. This paper critically reviews all these aspects pertaining to the recent models developed and adapted in some countries and also discusses the strategies followed and implications of these models. - Highlights: • Principal traffic noise models developed are reviewed. • Sound propagation algorithms used in traffic noise models are compared. • Implications of models are discussed.« less

  20. Steps towards understanding deep atmospheric heating in flares

    NASA Technical Reports Server (NTRS)

    Mauas, Pablo J. D.; Machado, Marcos E.

    1986-01-01

    Different aspects of the heating of the deep solar atmosphere during flares, including temperature minimum enhancements and white light emission, are discussed. The proper treatment of H(-) radiative losses is discussed, and compared with previous studies, as well as a quantitative analysis of the ionizing effect of nonthermal particles and ultraviolet radiation. It is concluded that temperature minimum heating may be a natural consequence of the global radiation transport in flares. The implications of these results are discussed within the context of homogeneous and inhomogeneous models of the solar atmosphere.

  1. BRIGHTEN YOUR CORNER, BROADCAST NO. 7464. UNIVERSITY EXPLORER.

    ERIC Educational Resources Information Center

    LEVY, CHARLES; HOWE, WILLIAM

    LIGHTING RECOMMENDATIONS ALONG WITH DESIGN IMPLICATIONS ARE DISCUSSED. COMMENTS OF SEVERAL LEADING LIGHTING AUTHORITIES ARE INCLUDED. A SERIES OF LIGHTING CONSIDERATIONS RECOMMENDS--(1) CHILDREN CAN ACQUIRE AN AWARENESS OF THEIR LUMINOUS ENVIRONMENT THROUGH EARLY TRAINING, (2) INTENSITY, DISTRIBUTION, HORIZONTAL OR VERTICAL POLARIZATION AND THE…

  2. Technology assessment and citizen action

    NASA Technical Reports Server (NTRS)

    Mottur, E. R.

    1975-01-01

    Citizen participation in the nation's total social, political, economic decisionmaking processes was studied. Impediments are discussed which prevent citizens from taking effective assessment action; these include finance, organization and motivation, and information. The proposal for establishing citizens assessment associations is considered along with implications of citizen assessment action.

  3. Simulation-Based Mission Rehearsal as a Human Activity System.

    DTIC Science & Technology

    1996-09-01

    explain this demonstrated importance of the people involved in MR, a human activity system model of simulation-based rehearsal was developed. It provides...Implications of this human activity system view are discussed, including: places in the mission preparation process where simulation can benefit operations

  4. Hypertension, End-Stage Renal Disease and Rehabilitation: A Look at Black Americans.

    ERIC Educational Resources Information Center

    Livingston, Ivor Lensworth; Ackah, Samuel

    1992-01-01

    Reviews the important relationship between end-stage renal disease (ESRD) and hypertension for African Americans; and considers issues associated with ESRD and the subsequent need for kidney transplants, including organ availability. Individual and societal implications of these diseases are discussed. (SLD)

  5. Projections for Our Changing Workplace and Work Force: Implications for Business Educators.

    ERIC Educational Resources Information Center

    Olivas, Louis

    1981-01-01

    Discusses issues that will have significance for business educators in the coming decade. These include increased government regulation, productivity, improved sophisticated technology, the workplace, women, the economy, research and development, the individual, privacy and rights, and the intellectual life. (CT)

  6. Improving Conditions for Principal Effectiveness: Policy Implications of Research on Effective Principals.

    ERIC Educational Resources Information Center

    Manasse, A. Lorri

    This paper reviews principal effectiveness research and suggests measures that might promote effective principalship. The first section discusses principals' behavior patterns and conditions bearing on their effectiveness. Topics examined include role ambiguity, goal setting behavior, leadership and initiative, management behaviors, instructional…

  7. Ethics and Intercultural Communication Education.

    ERIC Educational Resources Information Center

    Barna, LaRay M.

    The examination of ethical implications as part of intercultural communications courses and the responsibility of the instructor of these courses are discussed. Two questions are considered: Should ethics as a topic be included in courses in intercultural communications? What common problems in intercultural communication education could be in…

  8. Note: The Numbering of Postgraduate Research.

    ERIC Educational Resources Information Center

    Wafford, Geoffrey

    1984-01-01

    Implications of the trend toward funding only graduate research projects that have a high likelihood of completion are discussed, including allocation of funds according to institutions' completion rates, deemphasis on research quality and students' personal development, and overemphasis on producing graduates. A more balanced approach to research…

  9. Black Youths and Illegal Drugs.

    ERIC Educational Resources Information Center

    Joseph, Janice; Pearson, Patricia G.

    2002-01-01

    Examines the effect of drugs on black youths, discussing different types of drug involvement, reasons for drug involvement, extent and nature of involvement, drugs and crime, drugs and health issues, drug control strategies, and prevention. Policy implications include prioritizing drug prevention among black youths, providing alternatives to drug…

  10. Lunar rover vehicle - an implication for rehabilitation

    NASA Technical Reports Server (NTRS)

    Mcfarland, S. R.; Primeauk, G. R.

    1975-01-01

    The feasibility of adapting the lunar roving vehicle control concept to automobiles and vans for quadriplegics was investigated. Topics discussed include the current state of automobile handicapped controls, a description of the affected population, and a design for interfacing the control system into a passenger vehice.

  11. Visitors Abroad.

    ERIC Educational Resources Information Center

    Lepke, Helen; And Others

    Seven German-American cross-cultural social situations are presented in English, each followed by a multiple-choice question concerning the etiquette or cultural implications of the actions. An answer key provides comments to stimulate class discussion. These everyday situations occur in Germany or the United States, and include eating at a…

  12. The Instructional Role of the School Library Media Specialist: What Research Says to Us Now.

    ERIC Educational Resources Information Center

    Hodges, Gerald C.

    1981-01-01

    Reviews selected studies of the curricular and instructional role of the school library media specialist to identify predominant patterns in research findings, and discusses their implications for librarians, educators, administrators, and other professionals. It includes 23 references. (RAA)

  13. Legal Issues in Educational Technology: Implications for School Leaders.

    ERIC Educational Resources Information Center

    Quinn, David M.

    2003-01-01

    Discusses several legal issues involving the use of educational technology: Freedom of speech, regulation of Internet material harmful to minors, student-developed Web pages, harassment and hostile work environment, staff and student privacy, special education, plagiarism, and copyright issues. Includes recommendations for addressing technology…

  14. Hepatitis B: An Occupational Hazard for Special Educators.

    ERIC Educational Resources Information Center

    Bauer, Anne M.; Shea, Thomas M.

    1986-01-01

    A discussion of the transmission and prevention of hepatitis B focuses on implications of the disease for special educators, including maintaining confidentiality, providing education in the least restrictive environment, curriculum modifications in related behavioral/social areas, and personal risk. Relevant administrative and legal questions are…

  15. The Long March to Health.

    ERIC Educational Resources Information Center

    Silver, George A.

    1979-01-01

    The comprehensive medical care system being utilized in China is described. Topics discussed include: the availability of medical care, training of physicians, medical care costs, and the political and social implications of the Chinese system. Lessons the United States can learn from the Chinese experience are presented. (BT)

  16. Development Education and Disarmament Education.

    ERIC Educational Resources Information Center

    Burns, Robin

    1981-01-01

    Discusses development education as an educational process aimed at preparing people for participation in change and examines the implications for disarmament education. Development education is interpreted to include adult literacy education as well as a system of spreading basic concepts and encouraging and developing local initiatives. (DB)

  17. Higher derivative theories for interacting massless gravitons in Minkowski spacetime

    NASA Astrophysics Data System (ADS)

    Bai, Dong; Xing, Yu-Hang

    2018-07-01

    We study a novel class of higher derivative theories for interacting massless gravitons in Minkowski spacetime. These theories were first discussed by Wald decades ago, and are characterized by scattering amplitudes essentially different from general relativity and many of its modifications. We discuss various aspects of these higher derivative theories, including the Lagrangian construction, violation of asymptotic causality, scattering amplitudes, non-renormalization, and possible implications in emergent gravitons from condensed matter systems.

  18. Hierarchy of on-orbit servicing interfaces

    NASA Technical Reports Server (NTRS)

    Moe, Rud V.

    1989-01-01

    A series of equipment interfaces is involved in on-orbit servicing operations. The end-to-end hierarchy of servicing interfaces is presented. The interface concepts presented include structure and handling, and formats for transfer of resources (power, data, fluids, etc.). Consequences on cost, performance, and service ability of the use of standard designs or unique designs with interface adapters are discussed. Implications of the interface designs compatibility with remote servicing using telerobotic servicers are discussed.

  19. Review: Prevalence and co-occurrence of addictions in US ethnic/racial groups: Implications for genetic research.

    PubMed

    Luczak, Susan E; Khoddam, Rubin; Yu, Sheila; Wall, Tamara L; Schwartz, Anna; Sussman, Steve

    2017-08-01

    We conducted a review of the prevalence and co-occurrence of 12 types of addictions in US ethnic/racial groups and discuss the implications of the results for genetic research on addictions. We utilized MEDLINE and PsycINFO databases to review the literature on alcohol, tobacco, marijuana, illicit drugs, gambling, eating/food, internet, sex, love, exercise, work, and shopping. We present results for each addiction based on total US prevalence, prevalence within ethnic groups, and co-occurrence of addictions among ethnic groups when available. This review indicates very little research has examined the interrelationships of addictive behaviors among US ethnic groups. The studies that exist have focused nearly exclusively on comorbidity of substances and gambling behaviors. Overall findings suggest differences among US ethnic groups in prevalence of addictions and in prevalence of addiction among those who use substances or engage in gambling. Almost no ethnic group comparisons of other addictive behaviors including eating/food, internet, love, sex, exercise, work, and shopping were identified in the literature. Despite large-scale research efforts to examine alcohol and substance use disorders in the United States, few studies have been published that examine these addictive behaviors among ethnic groups, and even fewer examine co-occurrence and comorbidity with other addictions. Even with the limited studies, these findings have implications for genetic research on addictive behaviors. We include a discussion of these implications, including issues of population stratification, disaggregation, admixture, and the interplay between genetic and environmental factors in understanding the etiology and treatment of addictions. (Am J Addict 2017;26:424-436). © 2016 American Academy of Addiction Psychiatry.

  20. Early numeracy skills in preschool-aged children: a review of neurocognitive findings and implications for assessment and intervention.

    PubMed

    Raghubar, Kimberly P; Barnes, Marcia A

    2017-02-01

    The goals are to (1) provide a review of the typical and atypical development of early numeracy; (2) present what is known about the neurocognitive underpinnings of early numeracy; and (3) discuss the implications for early assessment and intervention. Studies on the development of typical and atypical early numeracy are reviewed with a particular focus on longitudinal findings including those from our work on spina bifida myelomeningocele. Implications of this research for assessment are presented. The paper ends with a discussion of early math interventions. Learning to count, identify numbers, and compare and manipulate quantities are key early numeracy skills. These are powerful predictors of school-age mathematical learning and performance. General neurocognitive abilities such as working memory and language, are also important for the development of early numeracy. It is recommended that early assessment for risk of mathematical learning difficulties include tests of both early number knowledge and key neurocognitive abilities. Math-specific interventions are most effective for improving early numeracy. There is currently little evidence that training of general cognitive functions transfers to mathematical learning. Understanding the development of early numeracy skills and their neurocognitive predictors offer important insights into early assessment and intervention for children at risk for or with mathematical learning difficulties.

  1. Genome-wide association studies in cardiac electrophysiology: recent discoveries and implications for clinical practice.

    PubMed

    Milan, David J; Lubitz, Steven A; Kääb, Stefan; Ellinor, Patrick T

    2010-08-01

    Genome-wide association studies have been increasingly used to study the genetics of complex human diseases. Within the field of cardiac electrophysiology, this technique has been applied to conditions such as atrial fibrillation, and several electrocardiographic parameters including the QT interval. While these studies have identified multiple genomic regions associated with each trait, questions remain, including the best way to explore the pathophysiology of each association and the potential for clinical utility. This review will summarize recent genome-wide association study results within cardiac electrophysiology and discuss their broader implications in basic science and clinical medicine. Copyright 2010 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  2. Electrical Space Conditioning.

    ERIC Educational Resources Information Center

    General Electric Co., Cleveland, OH. Large Lamp Dept.

    Integrated systems utilizing the heating potential of lighting equipment are discussed in terms of the implications for design and the methods for evaluation and control. General principles cover heat transfer, heat from lamps and luminaires, and control of lighting heat. Suggested systems include--(1) total control systems, (2) bleed-off systems,…

  3. Research in Behavior Modification; New Developments and Implications.

    ERIC Educational Resources Information Center

    Krasner, Leonard, Ed.; Ullmann, Leonard P., Ed.

    Fifteen articles by different authors discuss behavior modification in terms of research, training, and social application. Topics considered include the classification of behavioral pathology, the extension of learning principles to human behavior, studies of normal and deviant child behavior, operant conditioning of two speech-deficient boys,…

  4. Closing the Reference Interview: Implications for Policy and Practice.

    ERIC Educational Resources Information Center

    Nolan, Christopher W.

    1992-01-01

    Discusses reasons why patrons or librarians terminate the reference interview, including the content of the interview, interpersonal dynamics, and institutional or policy factors. Goals and objectives of the person terminating the interview are considered, and guidelines for policy development and performance improvement are offered. (30…

  5. Electronic Data Interchange: Selected Issues and Trends.

    ERIC Educational Resources Information Center

    Wigand, Rolf T.; And Others

    1993-01-01

    Describes electronic data interchange (EDI) as the application-to-application exchange of business documents in a computer-readable format. Topics discussed include EDI in various industries, EDI in finance and banking, organizational impacts of EDI, future EDI markets and organizations, and implications for information resources management.…

  6. High Technology and Education: An Economist's View.

    ERIC Educational Resources Information Center

    Carnoy, Martin

    1988-01-01

    Explores high technology industries' effects on labor markets, particularly on the division of labor, the organization of work, and the future of education. Discusses implications for demand and the distribution of that demand. Examines certain notions concerning knowledge production and work ethics and organization. Includes 34 references. (MLH)

  7. Nazi Education: A Case of Political Socialization.

    ERIC Educational Resources Information Center

    Hirsch, Herbert

    1988-01-01

    Discusses how the German Nazi party arranged for the political socialization of German children through public education in the 1930s. Topics include philosophy of the Nazi party, political socialization of teachers, and teaching materials for Nazi education. Implications for education's role in politics are explored. (CH)

  8. Legal Liabilities of Administrators.

    ERIC Educational Resources Information Center

    Underwood, Julie

    This chapter of "Principles of School Business Management" discusses the implications of several court cases for legal issues affecting the role of the school business official. The issues addressed include civil rights, negligence, contracts, criminal liability, tuition and fees, and student records. The chapter opens with a brief overview of…

  9. The Charge of the Byte Brigade: Educators Lead the Fourth Revolution.

    ERIC Educational Resources Information Center

    Gardner, David Pierpont

    1986-01-01

    Opportunities provided by computer technologies are considered from two perspectives: what they are enabling teachers and researchers to do and implications for the future. Processing information, opening access to the library, and coordinating telecommunications are discussed, including the University of California MELVYL system. (MLW)

  10. Simulation: Status of the Field.

    ERIC Educational Resources Information Center

    Twelker, Paul A.

    This paper describes selected nonschool uses of simulation and discusses the implications of each application for education in general. Most of the applications described pertain to instruction and include the provision of an environment for exercising or practicing the application of principles or skills. Applications which are examined include…

  11. A Review of Peer Social Development in Early Childhood.

    ERIC Educational Resources Information Center

    Goin, Robin P.

    1998-01-01

    Reviews the literature on young children's peer social development. Addresses implications of social learning theory and empirical research. Discusses recurring themes, including child/peer versus child/adult interactions, incorporation of toys and games, influence of mothers, and gender peer preferences. Considers areas lacking empirical support…

  12. Formative Assessment and the Design of Instructional Systems.

    ERIC Educational Resources Information Center

    Sadler, D. Royce

    1989-01-01

    Discusses the nature and function of formative assessment in the development of students' expertise for evaluating the quality of their own work. Highlights include the transition from teacher-supplied feedback to learner self-monitoring; qualitative judgments; communicating standards to students; multicriterion judgments; and implications for the…

  13. Planning for the Perils of CD-ROM.

    ERIC Educational Resources Information Center

    Zink, Steven D.

    1990-01-01

    Argues that, because of its meteoric entrance into the library marketplace, too few institutions have reviewed the implications of CD-ROM before making their purchases. Issues that need to be considered are discussed, including funding, costs, equipment requirements, optimal locations for workstations, security and viruses, human resources, user…

  14. Taking Teacher Responsibility into Account(ability): Explicating Its Multiple Components and Theoretical Status

    ERIC Educational Resources Information Center

    Lauermann, Fani; Karabenick, Stuart A.

    2011-01-01

    Accountability systems have important implications for schooling. Missing from discussions about their implementation, however, are ways they affect teacher responsibility. Responsibility has been insufficiently explicated in the education literature, including its impact on teacher motivation, emotion, and behavior. We propose that a…

  15. Insights about Psychotherapy Training and Curricular Sequencing: Portal of Discovery

    ERIC Educational Resources Information Center

    McGowen, K. Ramsey; Miller, Merry Noel; Floyd, Michael; Miller, Barney; Coyle, Brent

    2009-01-01

    Objective: The authors discuss the curricular implications of a research project originally designed to evaluate the instructional strategy of using standardized patients in a psychotherapy training seminar. Methods: The original project included second-year residents enrolled in an introductory psychotherapy seminar that employed sequential…

  16. Implications of Fuel-Efficient Vehicles on Ride Quality and Passenger Acceptance : Workshop Proceedings, Woods Hole, Massachusetts, September 6-8, 1978

    DOT National Transportation Integrated Search

    1979-08-01

    Four workshops were conducted under the auspices of the Transportation Research Board. The topics of discussion included ride quality and passenger acceptance problems associated with enhanced fuel efficiency of automobiles (Group A) and aircraft (Gr...

  17. Some Aspects of Childrearing Practices in Three Minority Subcultures in the United States.

    ERIC Educational Resources Information Center

    Williams, Herma B.; Williams, Eric

    1979-01-01

    Discusses cultural differences in child-rearing practices and values among Blacks, Mexican Americans, and American Indians. Outlines implications for schooling, including the incorporation of multicultural experiences into the classroom situation, and policy recommendations on the local, state, and federal levels. (GC)

  18. Chorio-Allantoic Membrane Grafting of Chick Limb Buds as a Class Practical.

    ERIC Educational Resources Information Center

    McLachlan, John C.

    1981-01-01

    A new method of carrying out grafts of early embryonic chick limb buds to the chick chorio-allantoic membrane and a processing schedule which renders cartilage elements visible in whole mount are discussed, including implications for the procedures and their results. (Author/DC)

  19. Improving care transitions through meaningful use stage 2: continuity of care document.

    PubMed

    Murphy, Lyn Stankiewicz; Wilson, Marisa L; Newhouse, Robin P

    2013-02-01

    In this department, Drs Murphy, Wilson, and Newhouse highlight hot topics in nursing outcomes, research, and evidence-based practice relevant to the nurse administrator. The goal is to discuss the practical implications for nurse leaders in diverse healthcare settings. Content includes evidence-based projects and decision making, locating measurement tools for quality improvement and safety projects, using outcome measures to evaluate quality, practice implications of administrative research, and exemplars of projects that demon strate innovative approaches to organizational problems. In this article, the authors describe the elements of continuity of care documentation, how sharing information can improve the quality and safety of care transitions and the implications for nurse executives.

  20. Effects of inflammation on social processes and implications for health.

    PubMed

    Moieni, Mona; Eisenberger, Naomi I

    2018-05-28

    Although at first glance inflammation and social behavior may appear unrelated, research points to an important role for inflammation in shaping social processes. This review summarizes findings in this field, specifically highlighting work that provides support for the idea that inflammation can lead to (1) increases in sensitivity to negative, threatening social experiences and (2) increases in sensitivity to positive, socially rewarding experiences. These diverging sensitivities in response to inflammation may depend on context and be adaptive for recuperation and recovery from illness. This review also discusses the implications of these findings for health and future research, including implications for depression, loneliness, and inflammatory disorders. © 2018 New York Academy of Sciences.

  1. Nanomaterials in the environment: from materials to high-throughput screening to organisms.

    PubMed

    Thomas, Courtney R; George, Saji; Horst, Allison M; Ji, Zhaoxia; Miller, Robert J; Peralta-Videa, Jose R; Xia, Tian; Pokhrel, Suman; Mädler, Lutz; Gardea-Torresdey, Jorge L; Holden, Patricia A; Keller, Arturo A; Lenihan, Hunter S; Nel, Andre E; Zink, Jeffrey I

    2011-01-25

    One of the challenges in the field of nanotechnology is environmental health and safety (EHS), including consideration of the properties of engineered nanomaterials (ENMs) that could pose dangers to the environment. Progress in the field of nanomaterial development and nanotoxicology was presented at the International Conference on the Environmental Implications of Nanotechnology at the California NanoSystems Institute (CNSI) on the UCLA campus on May 11-14, 2010. This event was cohosted by the University of California Center for the Environmental Implications of Nanotechnology (UC CEIN) and the Center for the Environmental Implications of NanoTechnology (CEINT) based at Duke University. Participants included scientists and scholars from various backgrounds, including chemistry, biology, engineering, nanomaterial science, toxicology, ecology, mathematics, sociology, and policy makers. The topics of discussion included safety evaluation of ENMs from an environmental perspective, nanotoxicology, ecotoxicology, safe design of ENMs, environmental risk assessment, public perception of nanotechnology, application of ENMs in consumer products, and many more. The UC CEIN presented data on their predictive toxicological approach to the assessment of ENM libraries, which were designed and synthesized to develop an understanding of the material properties that could lead to hazard generation at the cellular and organismal levels in the environment. This article will focus on the first metal oxide ENM library that was introduced to harmonize research activities in the UC CEIN, with particular emphasis on the safety assessment of ZnO on cells and organisms. Methods of decreasing the observed toxic effects will also be discussed as an integral component of the UC CEIN's activity in developing safer nanomaterials to lessen their environmental impacts.

  2. Implications of convection in the Moon and the terrestrial planets

    NASA Technical Reports Server (NTRS)

    Turcotte, Donald L.

    1987-01-01

    The early thermal and chemical evolution of the Moon is discussed. The rubidium-strontium, neodymium-samarium, and uranium-thorium-lead systems were studied. The relation of source region heterogeneity to the mixing associated with mantle convection is considered. Work on the application of fractal concepts to planetary geology and geophysics is also discussed. The fractal concept was applied to fragmentation, including the frequency-size distribution of meteorites, asteroids and particulate matter produced by impacts.

  3. Beginning the Dialogue on the e-Transformation: Behavior Analysis' First Massive Open Online Course (MOOC).

    PubMed

    Rehfeldt, Ruth Anne; Jung, Heidi L; Aguirre, Angelica; Nichols, Jane L; Root, William B

    2016-03-01

    The e-Transformation in higher education, in which Massive Open Online Courses (MOOCs) are playing a pivotal role, has had an impact on the modality in which behavior analysis is taught. In this paper, we survey the history and implications of online education including MOOCs and describe the implementation and results for the discipline's first MOOC, delivered at Southern Illinois University in spring 2015. Implications for the globalization and free access of higher education are discussed, as well as the parallel between MOOCs and Skinner's teaching machines.

  4. On the status of knowledge for using punishment implications for treating behavior disorders.

    PubMed Central

    Lerman, Dorothea C; Vorndran, Christina M

    2002-01-01

    In this paper, we review basic and applied findings on punishment and discuss the importance of conducting further research in this area. The characteristics of responding during punishment and numerous factors that interact with basic processes are delineated in conjunction with implications for the treatment of behavior disorders in clinical populations. We conclude that further understanding of punishment processes is needed to develop a highly systematic, effective technology of behavior change, including strategies for improving the efficacy of less intrusive procedures and for successfully fading treatment. PMID:12555918

  5. Netrins and UNC5 receptors in angiogenesis.

    PubMed

    Freitas, Catarina; Larrivée, Bruno; Eichmann, Anne

    2008-01-01

    Both neuronal and vascular development require guidance to establish a precise branching pattern of these systems in the vertebrate body. Several molecules implicated in axon navigation have also been shown to regulate vessel sprouting. Among these guidance cues, Netrins constitute a family of diffusible molecules with a bifuncional role in axon pathfinding. Recent findings implicate Netrins in other developmental processes, including vascular development. We here review recent studies and discuss the possible dual function of Netrins and its receptors during branching of blood vessels in developmental and pathological angiogenesis.

  6. Memory skills of deaf learners: implications and applications.

    PubMed

    Hamilton, Harley

    2011-01-01

    The author reviews research on working memory and short-term memory abilities of deaf individuals, delineating strengths and weaknesses. Among the areas of weakness that are reviewed are sequential recall, processing speed, attention, and memory load. Areas of strengths include free recall, visuospatial recall, imagery, and dual encoding. Phonological encoding and rehearsal appear to be strengths when these strategies are employed. The implications of the strengths and weaknesses for language learning and educational achievement are discussed. Research questions are posed, and remedial and compensatory classroom applications are suggested.

  7. Informal Taxation*

    PubMed Central

    Olken, Benjamin A.; Singhal, Monica

    2011-01-01

    Informal payments are a frequently overlooked source of local public finance in developing countries. We use microdata from ten countries to establish stylized facts on the magnitude, form, and distributional implications of this “informal taxation.” Informal taxation is widespread, particularly in rural areas, with substantial in-kind labor payments. The wealthy pay more, but pay less in percentage terms, and informal taxes are more regressive than formal taxes. Failing to include informal taxation underestimates household tax burdens and revenue decentralization in developing countries. We discuss various explanations for and implications of these observed stylized facts. PMID:22199993

  8. Variation in Place of Publication: A Model for Cataloging Simplification.

    ERIC Educational Resources Information Center

    Marker, Rhonda J.; Reagor, Melinda Ann

    1994-01-01

    Discussion of the revision of cataloging rules to simplify catalog records focuses on the information relating to publication, formerly called the imprint. Highlights include a review of cataloging codes; Library of Congress rules interpretations; the impact on bibliographic utilities; implications for technical and public services; and publishing…

  9. Traduccion automatica mediante el ordenador (Automatic Translation Using a Computer).

    ERIC Educational Resources Information Center

    Bueno, Julian L.

    This report on machine translation contains a brief history of the field; a description of the processes involved; a discussion of systems currently in use, including three software packages on the market (Teaching Assistant, Translate, and Globalink); reflections on implications for teaching; observations of results obtained when elements of…

  10. Biological Implications of the Nuclear Age.

    ERIC Educational Resources Information Center

    Atomic Energy Commission, Oak Ridge, TN. Div. of Technical Information.

    Reported are the proceedings of an interdisciplinary symposium on the effects on the biosphere of the release of radiation from the use of nuclear energy. Papers given include discussions of the use of radioisotopes in medicine, the benefits and possible consequences of peaceful applications of nuclear explosives, methods of estimating maximum…

  11. The Law of Higher Education, 1997 Supplement. Third Edition.

    ERIC Educational Resources Information Center

    Kaplin, William A.; Lee, Barbara A.

    This 1997 supplement to "The Law of Higher Education: A Comprehensive Guide to Lead Implications of Administrative Decision Making, Third Edition" (1995) (ED 383 256), includes discussions of court opinions, statutes, regulations, and related developments, and cites selected law journal articles, books, and other resources concerning the legal…

  12. A Pirate's Life: A Model and a Metaphor for Learning.

    ERIC Educational Resources Information Center

    Solomon, David L.

    2002-01-01

    Discusses various ways in which context may be interpreted to enhance learning and performance; illustrates domains of learning using a hockey team as an example; and suggests implications for learning, performance, and instructional design. Highlights include an ecological systems model; and examples of individual development, team learning, and…

  13. Women Surviving an Abusive Relationship: Grief and the Process of Change.

    ERIC Educational Resources Information Center

    Russell, Bonnie; Uhlemann, Max R.

    1994-01-01

    Surveys literature regarding women in abusive relationships focusing on key issues related to the change process that are consistent with the grieving process. Examines constructs of depression, guilt, and decision-making difficulty by comparing them within perspective of normal grieving. Discusses implications for counseling practice. Includes 35…

  14. Choosing the Standard of Care in Private Individual Defamation Cases.

    ERIC Educational Resources Information Center

    Caudill, Susan

    1989-01-01

    Examines private individual defamation cases that include discussion of whether the reasonably prudent publisher/editor or the reasonably prudent person should set the standard of care when negligence is at issue. Considers the implication of judicial reasoning in adopting one standard of care rather than the other. (RS)

  15. The Practice of Foreign Language Teaching.

    ERIC Educational Resources Information Center

    Cajkler, Wasyl; Addelman, Ron

    This book on aspects of modern foreign language teaching is written for trainee, new, and experienced teachers of students aged 11-16 and is intended as a practical source of information. The discussion of specific teaching issues includes implications for classroom practice. While not directly addressing Britain's new National Curriculum, it does…

  16. The Internationalisation of Higher Education: Some Ethical Implications

    ERIC Educational Resources Information Center

    Hoey, Michael

    2016-01-01

    All the papers included in this volume implicitly adopt an ethical stance towards the aspect of internationalisation that they investigate or discuss, but necessarily these stances only occasionally become explicit. In this paper, therefore, I look at the impact of internationalisation on universities and at their impact in turn on the…

  17. Interactions between Learner Characteristics and Optimal Instruction. Report No. 75-17.

    ERIC Educational Resources Information Center

    Brophy, Jere E.

    Possible implications of individual and group differences for educational research and practice are discussed. Differences include preference for cooperative versus competitive tasks; for working alone versus in a group; for structured versus unstructured learning situations; or for individual versus group reward contingencies; social class and…

  18. Tensions and Dilemmas in Leading Australia's Schools

    ERIC Educational Resources Information Center

    Gurr, David; Drysdale, Lawrie

    2012-01-01

    In this article we address several tensions and dilemmas that are impacting on Australian principals and other school leaders. The first section explores areas associated with improving teaching and learning and includes discussion of education trends, the construction of new learning environments and the implication of these for more…

  19. An Analysis of Ambulatory Teaching Situations for Faculty Development.

    ERIC Educational Resources Information Center

    Simpson, Deborah E.; And Others

    1990-01-01

    A study identified variables perceived by clinical medical faculty (n=20) to influence the ease or difficulty of teaching in the ambulatory care setting. Characteristics affecting the teaching situation included teacher, student, and patient characteristics. Implications for faculty development on teaching in the clinical setting are discussed.…

  20. The Death of Distance and the Rise of the Network Society.

    ERIC Educational Resources Information Center

    Saba, Farhad

    1999-01-01

    Discusses the rise of computer networks, telecommuting possibilities, the growing global economy, and possible resulting trends in the population of cities. Implications for higher education are suggested, including the centralization of certain core operations and the decentralization of other services to address the varied needs of students.…

  1. Typologies of Abuse among Afro-Trinidadian Women

    ERIC Educational Resources Information Center

    Hadeed, Linda F.; El-Bassel, Nabila

    2007-01-01

    This study examines typologies of abusive behaviors among Afro-Trinidadian women. A total of 17 women participated in a 2-hour, face-to-face interview. The findings suggest that women experience multiple types of abuse including physical, sexual, and emotional abuse and controlling behaviors. This article discusses the implications of the findings…

  2. Connecting Children's eCulture to Curriculum: Implications for Educators

    ERIC Educational Resources Information Center

    Laverick, Deanna M.

    2009-01-01

    This article discusses the benefits of including "children's eCulture" in school curricula. "Children's eCulture" is the culture of children as it relates to electronics and technology. Integrating children's eCulture into formal learning experiences allows teachers to promote multiple literacies in their students. The article will describe the…

  3. Review of Measurement Instruments and Procedures for Assessing Mobility Behaviors: Implications for Quantitative Measurement.

    ERIC Educational Resources Information Center

    Lehr, Donna H.

    The literature review identifies information regarding the emergence of mobility skills in infants and young handicapped children, including rolling, crawling, creeping, and walking. Sections discuss the following topics: assessment instruments relevant to mobility, the identification of developmental milestones in mobility, and a hierarchy of the…

  4. Parent-Child Play: Descriptions and Implications.

    ERIC Educational Resources Information Center

    MacDonald, Kevin, Ed.

    This volume provides the latest research and theory in the area of children's play with their parents. It includes discussions of the basic processes involved in parent-child play, parent-child play in atypical populations of children, and parent-child play from a cross-cultural perspective. Fifteen chapters follow the introduction, "Parents and…

  5. High Performance Computing and Networking for Science--Background Paper.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Office of Technology Assessment.

    The Office of Technology Assessment is conducting an assessment of the effects of new information technologies--including high performance computing, data networking, and mass data archiving--on research and development. This paper offers a view of the issues and their implications for current discussions about Federal supercomputer initiatives…

  6. Homeless Families in Rural and Non-Urban Communities.

    ERIC Educational Resources Information Center

    Rife, John C.; And Others

    1992-01-01

    Interviews with 247 homeless families (including 480 children) in 21 rural Ohio counties found that over two-thirds were headed by young single females. The most frequently cited reasons for homelessness were family conflict or dissolution and economic factors. Implications for service provision and policy development are discussed. (LP)

  7. Distance Education and Open Learning--Implications for Professional Development and Retraining.

    ERIC Educational Resources Information Center

    Scriven, Bruce

    1991-01-01

    Discusses the increasing need for professional development and retraining in Australia, especially for inservice teacher education, and describes new methods that may be more effective than traditional methods. Highlights include open learning; the modularization of courses and programs; the adaptation of instructional materials; and distance…

  8. Rural Poverty in America.

    ERIC Educational Resources Information Center

    Duncan, Cynthia M., Ed.

    This book consists of 13 essays discussing rural poverty in the United States, including historical and current conditions of rural poverty, underlying the social, economic, and political factors, and policy implications. The book is organized into three parts. Part 1 consists of four essays that provide a comprehensive description of the poverty…

  9. Black Men in the Medical Education Pipeline: Past, Present, and Future.

    ERIC Educational Resources Information Center

    Ready, Timothy; Nickens, Herbert W.

    1991-01-01

    Factors in the decline in Black male enrollment in medical schools are examined, including the general medical school applicant pool, popularity of undergraduate biology degrees, Black enrollment in college, poverty, and employment opportunities. Social implications, areas for further research, and potential solutions are discussed. (Author/MSE)

  10. Body Metaphors: Some Implications for Movement Education.

    ERIC Educational Resources Information Center

    Moore, Carol-Lynne

    1987-01-01

    Images of one's body, shared consciously or unconsciously by teacher and student, significantly influence all aspects of movement education including instructional philosophy, curriculum, and method. Discussed are the metaphors of body as beast, as machine, as objet d'art, and as child and how these metaphors affect instruction. (MT)

  11. Symptomatic Acute Toxoplasmosis in Returning Travelers

    PubMed Central

    Henao-Martínez, Andrés F; Franco-Paredes, Carlos; Palestine, Alan G; Montoya, Jose G

    2018-01-01

    Abstract We report a family who acquired acute toxoplasmosis after a trip to Central America. One member developed severe clinical manifestations including bilateral chorioretinitis, hepatitis, and myocarditis requiring therapy. Symptomatic acute toxoplasmosis is unusual and possesses a diagnostic challenge. We discuss the clinical and epidemiological implications, laboratory diagnosis, and treatment plan. PMID:29644250

  12. The Internet and Technical Services: A Point Break Approach.

    ERIC Educational Resources Information Center

    McCombs, Gillian M.

    1994-01-01

    Discusses implications of using the Internet for library technical services. Topics addressed include creative uses of the Internet; three basic applications on the Internet, i.e., electronic mail, remote log-in to another computer, and file transfer; electronic processing of information; electronic access to information; and electronic processing…

  13. Development of a Culturally Valid Counselor Burnout Inventory for Korean Counselors

    ERIC Educational Resources Information Center

    Yu, Kumlan; Lee, Sang Min; Nesbit, Elisabeth A.

    2008-01-01

    This article describes the development of the culturally valid Counselor Burnout Inventory. A multistage approach including item translation; item refinement; and evaluation of factorial validity, reliability, and score validity was used to test constructs and validation. Implications for practice and future research are discussed. (Contains 3…

  14. Brief Family Intervention: Effectiveness and the Importance of Including the Father

    ERIC Educational Resources Information Center

    Martin, Barclay

    1977-01-01

    A brief family intervention consisting of training in conflict resolution and contingency management was given to families reporting high rates of parent-child problems of long duration. The implications of these findings for a strong systems view of families and family therapy are discussed. (Author)

  15. Access to the Information Superhighway and Emerging Information Technologies by People with Disabilities.

    ERIC Educational Resources Information Center

    National Council on Disability, Washington, DC.

    This report discusses the growth of the National Information Infrastructure (NII), or the information superhighway, and its implications for people with disabilities. Advantages for people with disabilities include: increasing the ability of individuals with some types of disabilities to access and use information; decreasing personal isolation…

  16. The Argumentative Student in the Speech Communication Classroom: An Investigation and Implications.

    ERIC Educational Resources Information Center

    Infante, Dominic A.

    1982-01-01

    Discusses a recent conceptualization of argumentativeness. Reports on an investigation of characteristics of argumentative students, which included variables such as birth order, family size, high school training, college grade point average, etc. Supports the assumption that argumentativeness is a desirable communication trait and considers…

  17. The Internet as a Source of Academic Research Information: Findings of Two Pilot Studies.

    ERIC Educational Resources Information Center

    Kibirige, Harry M.; DePalo, Lisa

    2000-01-01

    Discussion of information available on the Internet focuses on two pilot studies that investigated how academic users perceive search engines and subject-oriented databases as sources of topical information. Highlights include information seeking behavior of academic users; undergraduate users; graduate users; faculty; and implications for…

  18. Teacher Labor Market Conditions in Canada: Balancing Demand and Supply.

    ERIC Educational Resources Information Center

    Press, Harold; Galway, Gerald; Barnes, Eldred

    2002-01-01

    Discusses teacher supply-and-demand issues in Canada. Includes a review of current research, the consequences of a teacher surplus, and efforts to address teacher shortages in Newfoundland and Labrador. Suggests teacher labor-market policy implications involving school districts, provisional governments, and teacher-training institutions. (PKP)

  19. The Diet Cola Man and Other Fantasies: Sexual Assertiveness or Harassment?

    ERIC Educational Resources Information Center

    Floerchinger, Debra

    1995-01-01

    The literature of sexual harassment, particularly on college campuses, is reviewed. Topics discussed include definition of sexual harassment, legal implications, the role of individual perceptions, victim and peer response to harassment, and development of institutional policy and strategies for combatting harassment. A substantial bibliography is…

  20. Exploring team working and shared leadership in multi-disciplinary cancer care.

    PubMed

    Willcocks, Stephen George

    2018-02-05

    Purpose The purpose of this paper is to explore the relevance of shared leadership to multi-disciplinary cancer care. It examines the policy background and applies concepts from shared leadership to this context. It includes discussion of the implications and recommendations. Design/methodology/approach This is a conceptual paper examining policy documents and secondary literature on the topic. While it focuses on the UK National Health Services, it is also relevant to other countries given they follow a broadly similar path with regard to multi-disciplinary working. Findings The paper suggests that shared leadership is a possible way forward for multi-disciplinary cancer care, particularly as policy developments are supportive of this. It shows that a shared perspective is likely to be beneficial to the further development of multi-disciplinary working. Research limitations/implications Adopting shared leadership needs to be explored further using appropriate empirical research. Practical implications The paper offers comments on the implications of introducing shared leadership and makes recommendations including being aware of the barriers to its implementation. Originality/value The paper offers an alternative view on leadership in the health-care context.

  1. Task Type and Group Motivation: Implications for a Behavioral Approach to Leadership in Small Groups.

    ERIC Educational Resources Information Center

    Latham, Van M.

    1987-01-01

    Discusses a theory of leadership effectiveness in small discussion/decision making groups developed to facilitate discussion and goal efficacy. Develops four leadership styles (coordinator, inventor, enthusiast, and director) focusing on two critical questions the leader must address. Discusses implications of the model for leadership training and…

  2. Music therapy and music medicine for children and adolescents.

    PubMed

    Yinger, Olivia Swedberg; Gooding, Lori

    2014-07-01

    This article summarizes the research on music therapy and music medicine for children and adolescents with diagnoses commonly treated by psychiatrists. Music therapy and music medicine are defined, effects of music on the brain are described, and music therapy research in psychiatric treatment is discussed. Music therapy research with specific child/adolescent populations is summarized, including disorders usually diagnosed in childhood, substance abuse, mood/anxiety disorders, and eating disorders. Clinical implications are listed, including suggestions for health care professionals seeking to use music medicine techniques. Strengths and weaknesses of music therapy treatment are discussed, as well as areas for future research. Published by Elsevier Inc.

  3. Papers presented to the Conference on Large Body Impacts and Terrestrial Evolution: Geological, Climatological, and Biological Implications

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The effects of large impacts on the environment are discussed and include thermal effects, atmospheric effects, changes in ocean temperatures, and geomagnetic anomalies. Biological factors such as extinction and increases in mutation development were investigated. Geological anomalies studied include stratigraphic gaps, extinction of entire boundary layers from the geological record, and geochemical oddities. Evidence was examined for impact cratering throughout the world.

  4. 'Now we call it research': participatory health research involving marginalized women who use drugs.

    PubMed

    Salmon, Amy; Browne, Annette J; Pederson, Ann

    2010-12-01

    In this paper, we discuss and analyse the strategies employed and challenges encountered when conducting a recent feminist participatory action research study with highly marginalized women who were illicit drug users in an inner city area of Vancouver, Canada. Through an analysis of the political economy of participatory praxis within current neoliberal contexts, we focus on three main areas: (i) reconceptualizing the pragmatics of participation; (ii) the microeconomic implications of participatory research, including ethical issues in payment for research participation; and (iii) the value and limits of using research as a tool for activism and empowerment. We conclude with a brief discussion of what we see to be some of the most salient social justice implications arising from feminist and participatory approaches to health research within neoliberal political spaces. © 2010 Blackwell Publishing Ltd.

  5. Venus tectonics - An overview of Magellan observations

    NASA Technical Reports Server (NTRS)

    Solomon, Sean C.; Smrekar, Suzanne E.; Bindschadler, Duane L.; Grimm, Robert E.; Kaula, William M.; Mcgill, George E.; Phillips, Roger J.; Saunders, R. S.; Schubert, Gerald; Squyres, Steven W.

    1992-01-01

    Magellan observations of the tectonic characteristics of highland regions on Venus are discussed with reference to competing theories for highland formation and evolution. Complex rigid terrain, or tessera, and the extent to which these elevated blocks of intensely deformed crust may be genetically related to highlands are then considered. Further, the tectonics of plains and lowland regions are examined, including deformation belts and coronae, and possible relations between such features and mantle dynamics. Implications of these observations for the global tectonics of Venus are discussed.

  6. Resource depletion promotes automatic processing: implications for distribution of practice.

    PubMed

    Scheel, Matthew H

    2010-12-01

    Recent models of cognition include two processing systems: an automatic system that relies on associative learning, intuition, and heuristics, and a controlled system that relies on deliberate consideration. Automatic processing requires fewer resources and is more likely when resources are depleted. This study showed that prolonged practice on a resource-depleting mental arithmetic task promoted automatic processing on a subsequent problem-solving task, as evidenced by faster responding and more errors. Distribution of practice effects (0, 60, 120, or 180 sec. between problems) on rigidity also disappeared when groups had equal time on resource-depleting tasks. These results suggest that distribution of practice effects is reducible to resource availability. The discussion includes implications for interpreting discrepancies in the traditional distribution of practice effect.

  7. FOXP2

    PubMed Central

    Nudel, Ron; Newbury, Dianne F

    2013-01-01

    The forkhead box P2 gene, designated FOXP2, is the first gene implicated in a speech and language disorder. Since its discovery, many studies have been carried out in an attempt to explain the mechanism by which it influences these characteristically human traits. This review presents the story of the discovery of the FOXP2 gene, including early studies of the phenotypic implications of a disruption in the gene. We then discuss recent investigations into the molecular function of the FOXP2 gene, including functional and gene expression studies. We conclude this review by presenting the fascinating results of recent studies of the FOXP2 ortholog in other species that are capable of vocal communication. WIREs Cogn Sci 2013, 4:547–560. doi: 10.1002/wcs.1247 PMID:24765219

  8. Biological and Clinical Implications of Comorbidities in Parkinson’s Disease

    PubMed Central

    Santiago, Jose A.; Bottero, Virginie; Potashkin, Judith A.

    2017-01-01

    A wide spectrum of comorbidities has been associated with Parkinson’s disease (PD), a progressive neurodegenerative disease that affects more than seven million people worldwide. Emerging evidence indicates that chronic diseases including diabetes, depression, anemia and cancer may be implicated in the pathogenesis and progression of PD. Recent epidemiological studies suggest that some of these comorbidities may increase the risk of PD and precede the onset of motor symptoms. Further, drugs to treat diabetes and cancer have elicited neuroprotective effects in PD models. Nonetheless, the mechanisms underlying the occurrence of these comorbidities remain elusive. Herein, we discuss the biological and clinical implications of comorbidities in the pathogenesis, progression, and clinical management, with an emphasis on personalized medicine applications for PD. PMID:29255414

  9. Treatment implications arising from a qualitative analysis of letters written by the nonoffending partners of men who have perpetrated child sexual abuse.

    PubMed

    Cahalane, Hilary; Parker, Gemma; Duff, Simon

    2013-01-01

    There is a dearth of current empirical research exploring the experiences of nonoffending partners, or women whose partners have perpetrated child sexual abuse. Existing literature is dated and focuses disproportionately on intrafamilial abuse. This research explores how nonoffending partners construct and understand their experiences using thematic analysis within a social constructionist framework. Findings indicate that discovery of a partner's sexual offending is a profoundly distressing experience. It can inhibit a woman's ability to process the broader implications of her partner's behavior, including issues of risk, the impact on the victim, and the additional protective responsibilities she must adopt in the future. Implications for future research and clinical practice are discussed.

  10. Recovering substance-impaired pharmacists’ views regarding occupational risks for addiction

    PubMed Central

    Merlo, Lisa J.; Cummings, Simone M.; Cottler, Linda B.

    2013-01-01

    Substance misuse, abuse, and dependence are serious problems among a minority of pharmacists. Though various environmental risk factors have been implicated, few data are available describing the underlying mechanisms or the extent to which the environmental risk factors actually contribute to the problem. In the present study, 32 pharmacists (72.7% male), under contract with a State impaired healthcare provider monitoring program, were recruited to participate in one of 6 guided group discussions regarding substance use among healthcare providers. These groups included 4-6 pharmacists, on average, and lasted approximately 60-90 minutes each. Participants anonymously contributed to the group discussions, providing in-depth commentary and describing their substance-related experiences. The discussions were digitally audio-recorded and transcribed for analysis using the Grounded Theory method. Results indicated that several occupational hazards unique to the pharmacy profession might contribute to the problem of substance use disorders among some members of this population, including: increased access to potent drugs of abuse, a stressful/unpleasant working environment, a culture that unofficially condones medication diversion, lack of education related to addiction, and lack of support for individuals seeking treatment. These results have important implications for the education of pharmacy students, the continuing education of licensed pharmacists, and the management of pharmacies in which these individuals work. PMID:22825228

  11. Practical Management of Patients with a History of Immediate Hypersensitivity to Common non-Beta-Lactam Drugs.

    PubMed

    Macy, Eric

    2016-01-01

    Immediate hypersensitivity reactions to medications are among the most feared adverse drug reactions, because of their close association with anaphylaxis. This review discusses a practical management approach for patients with a history of an immediate hypersensitivity to a non-beta-lactam medication, where reexposure to the implicated, or similar, medication is clinically necessary. Mechanisms associated with severe immediate hypersensitivity reactions include IgE-mediated mast cell activation, complement-mediated mast cell activation, and direct mast cell activation. Immediate hypersensitivity reactions may also be mediated by vasodilators, other pharmacologic mechanisms, or be secondary to underlying patient-specific biochemical abnormalities such as endocrine tumors or chronic spontaneous urticaria. The key features in the reaction history and the biochemistry of the implicated medication are discussed. Most individuals with a history of immediate hypersensitivity to a medication, who require reuse of that drug, can be safely retreated with a therapeutic course of the implicated drug after a full-dose challenge, graded challenge, or desensitization, with or without premedication and/or any preliminary diagnostic testing, depending on the specific situation.

  12. The Deakin/Graeff hypothesis: focus on serotonergic inhibition of panic

    PubMed Central

    Paul, Evan D.; Johnson, Philip L.; Shekhar, Anantha; Lowry, Christopher A.

    2014-01-01

    The Deakin/Graeff hypothesis proposes that different subpopulations of serotonergic neurons through topographically organized projections to forebrain and brainstem structures modulate the response to acute and chronic stressors, and that dysfunction of these neurons increases vulnerability to affective and anxiety disorders, including Panic Disorder. We outline evidence supporting the existence of a serotonergic system originally discussed by Deakin/Graeff that is implicated in the inhibition of panic-like behavioral and physiological responses. Evidence supporting this panic inhibition system comes from the following observations: 1) serotonergic neurons located in the ‘ventrolateral dorsal raphe nucleus (DRVL) as well as the ventrolateral periaqueductal gray (VLPAG) inhibit dorsal periaqueductal gray-elicited panic-like responses; 2) chronic, but not acute, antidepressant treatment potentiates serotonin’s panicolytic effect; 3) contextual fear activates a central nucleus of the amygdala-DRVL/VLPAG circuit implicated in mediating freezing and inhibiting panic-like escape behaviors; 4) DRVL/VLPAG serotonergic neurons are central chemoreceptors and modulate the behavioral and cardiorespiratory response to panicogenic agents such as sodium lactate and CO2. Implications of the panic inhibition system are discussed. PMID:24661986

  13. The Deakin/Graeff hypothesis: focus on serotonergic inhibition of panic.

    PubMed

    Paul, Evan D; Johnson, Philip L; Shekhar, Anantha; Lowry, Christopher A

    2014-10-01

    The Deakin/Graeff hypothesis proposes that different subpopulations of serotonergic neurons through topographically organized projections to forebrain and brainstem structures modulate the response to acute and chronic stressors, and that dysfunction of these neurons increases vulnerability to affective and anxiety disorders, including panic disorder. We outline evidence supporting the existence of a serotonergic system originally discussed by Deakin/Graeff that is implicated in the inhibition of panic-like behavioral and physiological responses. Evidence supporting this panic inhibition system comes from the following observations: (1) serotonergic neurons located in the 'ventrolateral dorsal raphe nucleus' (DRVL) as well as the ventrolateral periaqueductal gray (VLPAG) inhibit dorsal periaqueductal gray-elicited panic-like responses; (2) chronic, but not acute, antidepressant treatment potentiates serotonin's panicolytic effect; (3) contextual fear activates a central nucleus of the amygdala-DRVL/VLPAG circuit implicated in mediating freezing and inhibiting panic-like escape behaviors; (4) DRVL/VLPAG serotonergic neurons are central chemoreceptors and modulate the behavioral and cardiorespiratory response to panicogenic agents such as sodium lactate and CO2. Implications of the panic inhibition system are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Global change - Geoengineering and space exploration

    NASA Technical Reports Server (NTRS)

    Jenkins, Lyle M.

    1992-01-01

    Geoengineering options and alternatives are proposed for mitigating the effects of global climate change and depletion of the ozone layer. Geoengineering options were discussed by the National Academy of Science Panel on the Policy Implications of Greenhouse Warming. Several of the ideas conveyed in their published report are space-based or depend on space systems for implementation. Among the geoengineering options using space that are discussed include the use of space power systems as an alternative to fossil fuels for generating electricity, the use of lunar He-3 to aid in the development of fusion energy, and the establishment of a lunar power system for solar energy conversion and electric power beaming back to earth. Other geoengineering options are discussed. They include the space-based modulation of hurricane forces and two space-based approaches in dealing with ozone layer depletion. The engineering challenges and policy implementation issues are discussed for these geongineering options.

  15. Compulsive Buying among College Students: An Investigation of Its Antecedents, Consequences, and Implications for Public Policy.

    ERIC Educational Resources Information Center

    Roberts, James A.

    1998-01-01

    This study investigated the incidence, antecedents, consequences, and policy implications of compulsive buying among college students (n=300). Details contributing factors and discusses the relationship between credit card use and compulsive buying. Discusses the implications for consumer policy and suggestions for further research. (JOW)

  16. Cultural Aspects of Astrobiology: A Preliminary Reconnaissance at

    NASA Astrophysics Data System (ADS)

    Dick, Steven

    NASA's Astrobiology Roadmap, developed in 1998 by an interdisciplinary team of more than 150 individuals, recognizes ten science goals, 17 more specific science objectives, and four broad principles for the Astrobiology Program. Among the four operating principles, which emphasize multidisciplinarity, planetary stewardship and public outreach, is one that also recognizes broad societal interest for the implications of astrobiology, especially its extraterrestrial life component. Although several meetings ahve been convened in the past decade to discuss the implications of extraterrestrial intelligence, including NASA's own CASETI workshops in 1991-1992, none have surveyed the broader implications of astrobiology as now defined at NASA. In this paper we survey these societal questions raised by astrobiology, and then focus on those related to extraterrestrial life, and in particular how they might differ from SETI concerns already discussed. As we enter the new millennium, the necessity for interdisciplinary studies is increasingly recognized in academia, industry and government. Astrobiology provides an unprecedented opportunity to encourage the unity of knowledge, as recently proposed in E. O. Wilson's book Consilience: The Unity of Knowledge. It is incumbent on scientists to support research on the implications of their work, in particular large government-funded scientific projects. The deep insights such study may yield has been amply demonstrated by the Human Genome Project, among others.

  17. What Does Teacher Education Have to Do with Teaching? Implications for Diversity Studies

    ERIC Educational Resources Information Center

    Milner, H. Richard, IV

    2010-01-01

    Several concepts that are important for inclusion in any teacher education curriculum regarding diversity studies are elucidated in this article. The framing question of the discussion is: What are some relevant conceptions regarding issues of diversity that every teacher education program should consider including in its curriculum? The author…

  18. Workshop in the Education of Deaf-Blind Children.

    ERIC Educational Resources Information Center

    Weir, A. Charles, Ed.

    Included in the proceedings of a 1973 workshop on the education of deaf blind children are four papers on aspects of diagnosis and remediation. Roger Seelye discusses vision, visual anomalies, and the implications of low vision conditions such as cataracts, glaucoma, retrolental fibroplasia, and optic atrophy. The low vision aids workshop is…

  19. South Asia in the Global Electronic Village: Issues and Implications.

    ERIC Educational Resources Information Center

    Singh, Jagtar

    This paper discusses issues related to developments in computer and communication technologies in south Asia. The first section considers the Internet and its impact. Paradigm shifts and globalization are addressed in the second section, including the shifts away from stand alone libraries to library and information networks, ownership to access,…

  20. An Exploration of Female Travellers' Experiences of Guidance Counselling in Adult Education

    ERIC Educational Resources Information Center

    Doyle, Anne; Hearne, Lucy

    2012-01-01

    The proposed changes in the further education sector, including the rationalisation of the VEC into Local Education and Training Boards (LETBs) and the closures of the Senior Traveller Training Centres (STTCs), have implications for guidance counselling provision to the Traveller community. This article discusses female Travellers' experiences of…

  1. Outdoor Education Research: Implications for Social/Educational and Natural Resource Policy.

    ERIC Educational Resources Information Center

    Ewert, Alan; McAvoy, Leo

    This paper discusses the potential role of outdoor education research in the formation of public policies on natural resource management, social issues, and education. Some current environmental, social, and educational problems include the lack of public knowledge about natural resources at a time of heightened and conflicting demands for those…

  2. Dermatology in the cinema.

    PubMed

    Reese, V

    1995-12-01

    The depiction of skin disease in the cinema can be divided into three categories. These include skin findings on actors independent of the roles they portray, cutaneous disease used as a representation of evil, and skin disease represented realistically and sympathetically. Examples from a wide range of films are given, and implications for dermatologists and their patients are discussed.

  3. International Priorities for Teacher Education. World Assembly 1969.

    ERIC Educational Resources Information Center

    International Council on Education for Teaching, Washington, DC.

    Four papers are included in this pamphlet, the proceedings of the World Assembly at Abidjan, Ivory Coast. The keynote address, "A Turning Point in History" by Jaime Benitez, President of the University of Puerto Rico, discusses the Apollo 11 moon landing as an object lesson on values with international implications for shifting…

  4. Competition, Jobs, and Information Policy: The Case for Private-Sector Information Services: U.S. Patents.

    ERIC Educational Resources Information Center

    Ebersole, Joseph L.

    1994-01-01

    Discusses the argument for private-sector involvement in the distribution of government information, using U.S. patents as an example. Highlights include industry competitiveness; jobs creation; public access; identifying users; costs; user fees; existing systems of information dissemination; and implications of the Internet and NREN (National…

  5. Professional Development Leadership and the Diverse Learner. Issues in Science Education.

    ERIC Educational Resources Information Center

    Rhoton, Jack, Ed.; Bowers, Patricia, Ed.

    This book focuses on the professional development of teachers and discusses issues related to science education reform. The content of the book is divided into two parts. Part 1, Professional Development: Implications for Science Leadership, chapters include: (1) "The Role of the Science Leader in Implementing Standards-Based Science Programs"…

  6. A Commentary on "Integrated Reporting: A Review of Developments and Their Implications for the Accounting Curriculum"

    ERIC Educational Resources Information Center

    Correa Ruiz, Carmen

    2013-01-01

    In this commentary, Correa Ruiz notes that from his analysis, Owen (2013) identified the essential elements to be included in a modern professional accounting curriculum, described how Association of Chartered Certified Accountants (ACCA) has embedded "Integrated Reporting" in its curriculum, and discussed future curriculum development,…

  7. Social Isolation among Caregivers of Court-Involved Youths: A Qualitative Investigation

    ERIC Educational Resources Information Center

    Forsbrey, April D.; Frabutt, James M.; Smith, Heather L.

    2005-01-01

    The authors used qualitative research methodology to examine the lives of caregivers of court-involved youths. Caregiver social isolation, including overall lack of support, lack of school support, and isolation from self, emerged as a salient theme across 7 domains. Implications for counselors are discussed, and brief descriptions of several…

  8. Expedited Permanency Planning: Evaluation of the Kentucky Adoptions Opportunities Project.

    ERIC Educational Resources Information Center

    Martin, Mavin H.; Barbee, Anita P.; Antle, Becky F.; Sar, Bibhuti

    2002-01-01

    Presents evaluation findings of a 3-year Kentucky Adoptions Opportunities Project. Notes that a majority of children had one or both parents coping with multiple risk factors including mental illness, substance abuse, mental retardation, or family violence. Discusses major barriers to permanency, as well as policy and practice implications in the…

  9. Security Implications of Electronic Commerce: A Survey of Consumers and Businesses.

    ERIC Educational Resources Information Center

    Furnell, S. M.; Karweni, T.

    1999-01-01

    Examines general requirement for security technologies that provide a basis for trust in the electronic commerce environment. Discusses the results of two surveys that included general Internet users who are potential customers as well as commercial businesses, that considered attitudes to electronic commerce in general and options relating to…

  10. Racelessness in Private Schools: Should We Deconstruct the Racial and Cultural Identity of African-American Adolescents?

    ERIC Educational Resources Information Center

    Fordham, Signithia

    1991-01-01

    Paper argues that racelessness is a concept that symbolizes efforts to deconstuct historically constituted relationships between African-American and whites, including intrusion into the notion of academic adequacy and African-American students' enrollment in private schools. The paper discusses implications of racelessness for African-American…

  11. The Puzzle of Inheritance: Genetics and the Methods of Science.

    ERIC Educational Resources Information Center

    Cutter, Mary Ann G.; Drexler, Edward; Friedman, B. Ellen; McCullough, Laurence B.; McInerney, Joseph D.; Murray, Jeffrey C.; Rossiter, Belinda; Zola, John

    This instructional module contains a description of the Human Genome Project (HGP). A discussion of issues in the philosophy of science and some of the ethical, legal, and social implications of research in genetics, and a survey of fundamental genetics concepts and of new, nontraditional concepts of inheritance are also included. Six…

  12. Consumer Protection, Leadership Models, and Training and Development.

    ERIC Educational Resources Information Center

    Coleman, Donald G.; Heun, Richard E.

    This paper examines several models of leadership style that are widely used in staff development workshops and seminars for managers. The discussion focuses mainly on the implications and possible dangers for training subjects of these models, which include two-factor models, such as those of Barnard and Halpin, and orthogonal grid models, such as…

  13. Ten Commonalities of Suicide and Some Implications for Public Policy.

    ERIC Educational Resources Information Center

    Shneidman, Edwin S.

    This paper describes 10 common characteristics of suicide that pertain to suicide committed at any age. Each characteristic is defined and analyzed, with specific approaches to treatment identified. The 10 characteristics, based on clinical experience and the relevant work of others, are listed. The commonalities discussed include: (1) the common…

  14. A Lab of Her Own? Portrayals of Female Characters on Children's Educational Science Programs.

    ERIC Educational Resources Information Center

    Steinke, Jocelyn; Long, Marilee

    1996-01-01

    Describes a study that examined the portrayals of female characters on four educational science television series for children and discusses those portrayals in the light of other research on television and socialization. Topics include children's perceptions of occupational sex roles; theories of sex-role development; and implications for future…

  15. Creating a New Definition of Library Cooperation: Past, Present, and Future Models.

    ERIC Educational Resources Information Center

    Lenzini, Rebecca T.; Shaw, Ward

    1991-01-01

    Describes the creation and purpose of the Colorado Alliance of Research Libraries (CARL), the subsequent development of CARL Systems, and its current research projects. Topics discussed include online catalogs; UnCover, a journal article database; full text data; document delivery; visual images in computer systems; networks; and implications for…

  16. The Monetary Rewards of Migration Within the U.S.

    ERIC Educational Resources Information Center

    Wertheimer, Richard F., II

    This study focuses on the economic benefits derived by the migrant from migration. The report presents a methodology for computing monetary benefits, an estimate of these benefits, and implications of the findings for public policy. Included are a discussion of domestic migration and public policy, an economic theory of migration, an explanation…

  17. Paying for Children's Medical Care: Is the Medicare Experience Helpful?

    ERIC Educational Resources Information Center

    Moon, Marilyn; And Others

    1993-01-01

    Discusses the implications of the Medicare program's rate setting system on health care reform and considers whether such a procedure could be applied to a health insurance system that included children. Examines desirable characteristics of a provider payment system, special health needs of children, and hospital and physician payment issues.…

  18. How to Use Color Displays Effectively: The Elements of Color Vision and Their Implications for Programmers.

    ERIC Educational Resources Information Center

    Durrett, John; Trezona, Judi

    1982-01-01

    Discusses physiological and psychological aspects of color. Includes guidelines for using color effectively, especially in the development of computer programs. Indicates that if applied with its limitations and requirements in mind, color can be a powerful manipulator of attention, memory, and understanding. (Author/JN)

  19. Human Intraocular Filariasis Caused by Dirofilaria sp. Nematode, Brazil

    PubMed Central

    Diniz, Daniel G.; Dantas-Torres, Filipe; Casiraghi, Maurizio; de Almeida, Izabela N.F.; de Almeida, Luciana N.F.; Nascimento dos Santos, Jeannie; Furtado, Adriano Penha; Sobrinho, Edmundo F. de Almeida; Bain, Odile

    2011-01-01

    A case of human intraocular dirofilariasis is reported from northern Brazil. The nematode was morphologically and phylogenetically related to Dirofilaria immitis but distinct from reference sequences, including those of D. immitis infesting dogs in the same area. A zoonotic Dirofilaria species infesting wild mammals in Brazil and its implications are discussed. PMID:21529396

  20. Training Humanities Doctoral Students in Collaborative and Digital Multimedia

    ERIC Educational Resources Information Center

    Ensslin, Astrid; Slocombe, Will

    2012-01-01

    This study reports on the pedagogic rationale, didactic design and implications of an AHRC-funded doctoral training scheme in collaborative and digital multimedia in the humanities. In the second part of this article we discuss three areas of provision that were identified as particularly significant and/or controversial. These include (1) desktop…

  1. Owen Bradford Butler: Corporate America's Evangelist for the Educationally Disadvantaged.

    ERIC Educational Resources Information Center

    Matthews, Frank L.

    1989-01-01

    The retired Procter & Gamble corporate leader and member of the Committee for Economic Development (CED) discusses the crisis in the American education system and his efforts for reform. Subjects covered include implications for business and the nation, business and federal reform initiatives, and the mandate for community-wide involvement.…

  2. Genetics, Environment, and Behavior: Implications for Educational Policy.

    ERIC Educational Resources Information Center

    Ehrman, Lee, Ed.; And Others

    The contents of this book, which presents the fruits of one of a series of conferences organized by the National Research Council Committee on Basic Research in Education, includes 12 papers, with discussion and comments: "Introductory Remarks," Ernst W. Caspari; "Quantitative Aspects of Genetics and Environment in the Determination of Behavior,"…

  3. Climate-Change Science and Policy: What Do We Know? What Should We Do

    DTIC Science & Technology

    2010-09-06

    These briefing charts discuss climate change science and policy including: the essence of the challenge, five myths and their refutations, climate ... change risks and impact going forward, available options, how much mitigation, how soon?, mitigation supply curve and its implications, and the Obama Administration’s strategy.

  4. Compressed Speech Technology: Implications for Learning and Instruction.

    ERIC Educational Resources Information Center

    Sullivan, LeRoy L.

    This paper first traces the historical development of speech compression technology, which has made it possible to alter the spoken rate of a pre-recorded message without excessive distortion. Terms used to describe techniques employed as the technology evolved are discussed, including rapid speech, rate altered speech, cut-and-spliced speech, and…

  5. The Encultured Body: Policy Implications for Healthy Body Image and Disordered Eating Behaviours.

    ERIC Educational Resources Information Center

    Gaskill, Deanne, Ed.; Sanders, Fran, Ed.

    The purpose of this publication is to provide discussion of some of the most difficult and controversial issues surrounding body image and eating disorders, specifically, anorexia nervosa and bulimia nervosa. It includes contributions from a number of nationally and internationally recognized clinicians and researchers in the field. It also…

  6. A New Role for Education in Economic Development: Tomorrow's Economy Today.

    ERIC Educational Resources Information Center

    Blakely, Edward J.

    1997-01-01

    Argues the role of education as a wealth-generating and transformative resource for both local and national economies as communities shift from assembly-line to high-tech economies. Discussions include educational policy implications during a shift to high-technology industries, school districts as job generators, and universities as economic…

  7. The Employment Counselor as a Vocational Counselor.

    ERIC Educational Resources Information Center

    Bluhm, Harry P.

    The purpose of this paper is to explore the role of the employment counselor as a vocational counselor to dropout discussing such topics as: (1) functions, (2) problems of dropouts and their counseling implications, and (3) counseling the dropout. Included in the functions are: (1) representing the Employment Office in coordinating all programs…

  8. The Tricentennial People: Human Applications of the New Genetics.

    ERIC Educational Resources Information Center

    Neumann, Marguerite, Ed.

    This symposium focused on the social, political, and ethical implications of the current trends in genetic research. Four papers are presented here along with transcripts of the accompanying discussions. The topics include: (1) genetics and the biological basis of the human condition; (2) the pros and cons of genetic counseling; (3) genetics and…

  9. Tuition and Fees in the West 2014-15. Policy Insights

    ERIC Educational Resources Information Center

    Bransberger, Peace

    2015-01-01

    This issue of "Policy Insights" reviews the results from the annual survey, conducted by the Western Interstate Commission for Higher Education (WICHE), of tuition and fees at public colleges and universities in the WICHE region, and discusses related policy implications. The WICHE region includes 15 states--Alaska, Arizona, California,…

  10. Internet Telephony: The Next Killer Application? (Or, How I Cut My Long-Distance Phone Bill to Nothing!).

    ERIC Educational Resources Information Center

    Learn, Larry L., Ed.

    1995-01-01

    Discusses the evolution of real-time telephony and broadcast applications using the Internet; resulting issues and opportunities; and future implications for regulators, Internet users, and service providers. Topics covered include bandpass, packetized voice, IP structures, class D datagrams, software, technical parameters, legal and regulatory…

  11. Verbal Playfulness as a Rapport-Building Strategy in Conversation among Chinese Female Friends.

    ERIC Educational Resources Information Center

    Kuo, Sai-hua

    This study investigated verbal play, including teasing and self-mocking in a naturally occurring conversation, among four Chinese female friends. The study illustrates how these speakers engage in teasing activities and then discusses the implications and significance of verbal play. Examples are taken from a casual, playful conversation…

  12. Refocusing Schools for Dropout Prevention: With Implications For Teacher Education.

    ERIC Educational Resources Information Center

    Rhodes, Donna C.; McMillan, Samuel H., Jr.

    A description is given of "Operation Rescue," a program designed to find and implement solutions to the dropout problem. A discussion of the reasons students drop out of school takes into consideration the pressures of society that tend to overwhelm at-risk students. These include environmental, academic, survival, and social factors…

  13. New Approaches to the Teaching of the Classics.

    ERIC Educational Resources Information Center

    Masciantonio, Rudolph, Ed.; Weislogel, Stephen, Ed.

    This four-part report of the 1971-72 Classical Association of the Atlantic States Working Committee deals with the rationale for new approaches and curriculums for schools and colleges. Implications of the new approaches in teacher education are also teated. The major section treating new model curriculums and approaches includes discussion of:…

  14. Freedom of the Press vs. Public Access.

    ERIC Educational Resources Information Center

    Schmidt, Benno C., Jr.

    This book surveys the implications of freedom of the press for a constitutionally rooted public right of access to electronic and print media. Part one provides general perspectives on access to the media, including discussions of access in relation to the Supreme Court, to First Amendment history and theory, to current perceptions of the press,…

  15. Managing childhood chronic illness: parent perspectives and implications for parent-provider relationships.

    PubMed

    Kratz, Lyn; Uding, Nancy; Trahms, Cristine M; Villareale, Nanci; Kieckhefer, Gail M

    2009-12-01

    When children have special health care needs, parents assume the roles of care coordinator, medical expert, and systems advocate as well as their typical parenting roles. They face many challenges in managing their child's chronic condition in the context of everyday life. Health care providers are uniquely positioned to assist parents in meeting those challenges and to promote parent competency and confidence in their child's care. The data for this analysis were collected during classes for parents of children with chronic conditions who took part in a randomized controlled study of a curriculum's effectiveness. During facilitated discussions, parents discussed challenges they faced and generated strategies they found helpful. Qualitative data analysis revealed dominant themes across subject areas. Challenges included social isolation, strained relationships and ongoing frustrations with health care and educational systems. Helpful strategies focused on being prepared, connecting with peers, becoming an advocate, developing partnerships and caring for one's self. Implications for health care providers include: understanding common challenges parents face; promoting parent-to-parent connections; and building partnerships with parents and their children with special needs.

  16. Breaking bad news revisited: the push for negotiated disclosure and changing practice implications.

    PubMed

    Arber, Anne; Gallagher, Ann

    2003-04-01

    This article revisits the ethical, legal, professional and emotional issues involved with disclosing bad news. The authors examine the push for disclosure that has come from a number of quarters in the UK, including ethical and legal challenges, in particular the Bristol Royal Inquiry Report, professional codes of conduct, health policy and the expectations of the public. The contribution of nurses to breaking bad news is not widely discussed in the literature. With the development of new nursing roles and evidence-based practice it is timely to consider the role of nurses in this process. The article highlights some limitations with current guidelines for breaking bad news, in particular, that these guidelines tend to be constructed from a professional standpoint and lack patient-centred evidence. The issue of emotional labour and how it relates to giving bad news is discussed with respect to professional staff and patients. The article concludes by raising some practice implications, including: the importance of context and continuity; the significance of information and support; the desirable qualities of the professional; and issues to consider in determining patient preferences.

  17. My genes made me do it? The implications of behavioural genetics for responsibility and blame.

    PubMed

    Levitt, Mairi; Manson, Neil

    2007-03-01

    The idea of individual responsibility for action is central to our conception of what it is to be a person. Behavioural genetic research may seem to call into question the idea of individual responsibility with possible implications for the criminal justice system. These implications will depend on the understandings of the various agencies and professional groups involved in responding to violent and anti-social behaviour, and, the result of negotiations between them over resulting practice. The paper considers two kinds of approaches to the question of responsibility and 'criminal genes' arising from a sociological and philosophical perspective respectively. One is to consider the social context and possible practical implications of research into 'criminal genes' which will later be examined through interviews and discussions with a range of experts including lawyers and social workers. A second and different kind of approach is to ask whether the findings of behavioural genetics ought to have implications for attributions of responsibility. Issues of genetic influence are central to both approaches.

  18. Stark laws and fair market value exceptions: an introduction.

    PubMed

    Siebrasse, Paul B

    2007-01-01

    This article will focus on one aspect of complexity in modern healthcare, namely the implications of Stark laws and other fraud and abuse provisions, including anti-kickback statutes and HIPAA. Also, this article explores the prevalence of fair market value as an exception in the Stark laws and discusses the meanings of those exceptions. Finally, the article explores basic approaches to assessing fair market value, including cost, income, and marketing approaches.

  19. An overview of the Software Engineering Laboratory

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This report describes the background and structure of the SEL organization, the SEL process improvement approach, and its experimentation and data collection process. Results of some sample SEL studies are included. It includes a discussion of the overall implication of trends observed over 17 years of process improvement efforts and looks at the return on investment based on a comparison of total investment in process improvement with the measurable improvements seen in the organization's software product.

  20. Adaptive approaches to licensing, health technology assessment, and introduction of drugs and devices.

    PubMed

    Husereau, Don; Henshall, Chris; Jivraj, Jamil

    2014-07-01

    Adaptive approaches to the introduction of drugs and medical devices involve the use of an evolving evidence base rather than conventional single-point-in-time evaluations as a proposed means to promote patient access to innovation, reduce clinical uncertainty, ensure effectiveness, and improve the health technology development process. This report summarizes a Health Technology Assessment International (HTAi) Policy Forum discussion, drawing on presentations from invited experts, discussions among attendees about real-world case examples, and background paper. For adaptive approaches to be understood, accepted, and implemented, the Forum identified several key issues that must be addressed. These include the need to define the goals of and to set priorities for adaptive approaches; to examine evidence collection approaches; to clarify the roles and responsibilities of stakeholders; to understand the implications of adaptive approaches on current legal and ethical standards; to determine costs of such approaches and how they will be met; and to identify differences in applying adaptive approaches to drugs versus medical devices. The Forum also explored the different implications of adaptive approaches for various stakeholders, including patients, regulators, HTA/coverage bodies, health systems, clinicians, and industry. A key outcome of the meeting was a clearer understanding of the opportunities and challenges adaptive approaches present. Furthermore, the Forum brought to light the critical importance of recognizing and including a full range of stakeholders as contributors to a shared decision-making model implicit in adaptive pathways in future discussions on, and implementation of, adaptive approaches.

  1. The Privacy and Security Implications of Open Data in Healthcare.

    PubMed

    Kobayashi, Shinji; Kane, Thomas B; Paton, Chris

    2018-04-22

     The International Medical Informatics Association (IMIA) Open Source Working Group (OSWG) initiated a group discussion to discuss current privacy and security issues in the open data movement in the healthcare domain from the perspective of the OSWG membership.  Working group members independently reviewed the recent academic and grey literature and sampled a number of current large-scale open data projects to inform the working group discussion.  This paper presents an overview of open data repositories and a series of short case reports to highlight relevant issues present in the recent literature concerning the adoption of open approaches to sharing healthcare datasets. Important themes that emerged included data standardisation, the inter-connected nature of the open source and open data movements, and how publishing open data can impact on the ethics, security, and privacy of informatics projects.  The open data and open source movements in healthcare share many common philosophies and approaches including developing international collaborations across multiple organisations and domains of expertise. Both movements aim to reduce the costs of advancing scientific research and improving healthcare provision for people around the world by adopting open intellectual property licence agreements and codes of practice. Implications of the increased adoption of open data in healthcare include the need to balance the security and privacy challenges of opening data sources with the potential benefits of open data for improving research and healthcare delivery. Georg Thieme Verlag KG Stuttgart.

  2. Relationships between topographic roughness and aeolian processes

    NASA Technical Reports Server (NTRS)

    Greeley, Ronald; Lancaster, N.; Gaddis, L.; Rasmussen, K. R.; White, B. R.; Saunders, R. S.; Wall, S.; Dobrovolskis, Anthony R.; Iversen, J. D.

    1991-01-01

    The interaction between winds and desert surfaces has important implications for sediment transport on Earth, Mars, and Venus, and for understanding the relationships between radar backscatter and aerodynamic roughness as part of the NASA Shuttle Imaging radar (SIR-C) Mission. Here, researchers report results from measurements of boundary layer wind profiles and surface roughness at sites in Death Valley and discuss their implications. The sites included a flat to undulating gravel and sand reg, alluvial fans, and a playa. Estimates of average particle size composition of Death Valley sites and arithmetic mean values of aerodynamic roughness are given in tabular form.

  3. Methodological issues in medical workforce analysis: implications for regional Australia.

    PubMed

    Hays, R B; Veitch, P C; Franklin, L; Crossland, L

    1998-02-01

    Medical workforce data have a profound impact on health policy formulation, but derived doctor population ratios (DPR) are often more relevant to plotting national trends than providing a detailed regional or local workforce perspective. Regional workforce data may be more useful if national approaches are augmented by local information. In developing a detailed workforce analysis for one region of Australia, the authors encountered several challenging methodological issues, including the accuracy of medical workforce databases, clarity of definition of community boundaries, interpretation of workforce definitions and the difficulty accounting for local community needs. This paper discusses the implications for regional workforce research.

  4. Innovative Advances in Connectivity and Community Pharmacist Patient Care Services: Implications for Patient Safety.

    PubMed

    Bacci, Jennifer L; Berenbrok, Lucas A

    2018-06-07

    The scope of community pharmacy practice has expanded beyond the provision of drug product to include the provision of patient care services. Likewise, the community pharmacist's approach to patient safety must also expand beyond prevention of errors during medication dispensing to include optimization of medications and prevention of adverse events throughout the entire medication use process. Connectivity to patient data and other healthcare providers has been a longstanding challenge in community pharmacy with implications for the delivery and safety of patient care. Here, we describe three innovative advances in connectivity in community pharmacy practice that enhance patient safety in the provision of community pharmacist patient care services across the entire medication use process. Specifically, we discuss the growing use of immunization information systems, quality improvement platforms, and health information exchanges in community pharmacy practice and their implications for patient safety. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  5. Recognition for positive behavior as a critical youth development construct: conceptual bases and implications on youth service development.

    PubMed

    Law, Ben M F; Siu, Andrew M H; Shek, Daniel T L

    2012-01-01

    Recognition for positive behavior is an appropriate response of the social environment to elicit desirable external behavior among the youth. Such positive responses, rendered from various social systems, include tangible and intangible reinforcements. The following theories are used to explain the importance of recognizing positive behavior: operational conditioning, observational learning, self-determination, and humanistic perspective. In the current work, culturally and socially desirable behaviors are discussed in detail with reference to Chinese adolescents. Positive behavior recognition is especially important to adolescent development because it promotes identity formation as well as cultivates moral reasoning and social perspective thinking from various social systems. The significance of recognizing positive behavior is illustrated through the support, tutorage, invitation, and subsidy provided by Hong Kong's social systems in recognition of adolescent volunteerism. The practical implications of positive behavior recognition on youth development programs are also discussed in this work.

  6. Collective Psychological Ownership and Intergroup Relations.

    PubMed

    Verkuyten, Maykel; Martinovic, Borja

    2017-11-01

    Whereas much social psychological research has studied the in-group and out-group implications of social categorization and collective identity ("we"), little research has examined the nature and relevance of collective psychological ownership ("ours") for intergroup relations. We make a case for considering collective psychological ownership as an important source of intergroup tensions. We do so by integrating theory and research from various social sciences, and we draw out implications for future social psychological research on intergroup relations. We discuss collective psychological ownership in relation to the psychology of possessions, marking behavior, intergroup threats, outgroup exclusion, and in-group responsibility. We suggest that the social psychological processes discussed apply to a range of ownership objects (territory, buildings, cultural artifacts) and various intergroup settings, including international, national, and local contexts, and in organizations and communities. We conclude by providing directions for future research in different intergroup contexts.

  7. Personality and Depression: Explanatory Models and Review of the Evidence

    PubMed Central

    Klein, Daniel N.; Kotov, Roman; Bufferd, Sara J.

    2012-01-01

    Understanding the association between personality and depression has implications for elucidating etiology and comorbidity, identifying at-risk individuals, and tailoring treatment. We discuss seven major models that have been proposed to explain the relation between personality and depression, and we review key methodological issues, including study design, the heterogeneity of mood disorders, and the assessment of personality. We then selectively review the extensive empirical literature on the role of personality traits in depression in adults and children. Current evidence suggests that depression is linked to traits such as neuroticism/negative emotionality, extraversion/positive emotionality, and conscientiousness. Moreover, personality characteristics appear to contribute to the onset and course of depression through a variety of pathways. Implications for prevention and prediction of treatment response are discussed, as well as specific considerations to guide future research on the relation between personality and depression. PMID:21166535

  8. Evolving food retail environments in Thailand and implications for the health and nutrition transition.

    PubMed

    Banwell, Cathy; Dixon, Jane; Seubsman, Sam-Ang; Pangsap, S; Kelly, Matthew; Sleigh, Adrian

    2013-04-01

    To investigate evolving food retail systems in Thailand. Rapid assessment procedures based on qualitative research methods including interviews, focus groups discussions and site visits. Seven fresh markets located in the four main regions of Thailand. Managers, food specialists, vendors and shoppers from seven fresh markets who participated in interviews and focus group discussions. Fresh markets are under economic pressure and are declining in number. They are attempting to resist the competition from supermarkets by improving convenience, food diversity, quality and safety. Obesity has increased in Thailand at the same time as rapid growth of modern food retail formats has occurred. As fresh markets are overtaken by supermarkets there is a likely loss of fresh, healthy, affordable food for poorer Thais, and a diminution of regional culinary culture, women's jobs and social capital, with implications for the health and nutrition transition in Thailand.

  9. Traumatogenic Processes and Pathways to Mental Health Outcomes for Sexual Minorities Exposed to Bias Crime Information.

    PubMed

    Lannert, Brittany K

    2015-07-01

    Vicarious traumatization of nonvictim members of communities targeted by bias crimes has been suggested by previous qualitative studies and often dominates public discussion following bias events, but proximal and distal responses of community members have yet to be comprehensively modeled, and quantitative research on vicarious responses is scarce. This comprehensive review integrates theoretical and empirical literatures in social, clinical, and physiological psychology in the development of a model of affective, cognitive, and physiological responses of lesbian, gay, and bisexual individuals upon exposure to information about bias crimes. Extant qualitative research in vicarious response to bias crimes is reviewed in light of theoretical implications and methodological limitations. Potential pathways to mental health outcomes are outlined, including accumulative effects of anticipatory defensive responding, multiplicative effects of minority stress, and putative traumatogenic physiological and cognitive processes of threat. Methodological considerations, future research directions, and clinical implications are also discussed. © The Author(s) 2014.

  10. Motivating forces of human actions. Neuroimaging reward and social interaction.

    PubMed

    Walter, Henrik; Abler, Birgit; Ciaramidaro, Angela; Erk, Susanne

    2005-11-15

    In neuroeconomics, reward and social interaction are central concepts to understand what motivates human behaviour. Both concepts are investigated in humans using neuroimaging methods. In this paper, we provide an overview about these results and discuss their relevance for economic behaviour. For reward it has been shown that a system exists in humans that is involved in predicting rewards and thus guides behaviour, involving a circuit including the striatum, the orbitofrontal cortex and the amygdala. Recent studies on social interaction revealed a mentalizing system representing the mental states of others. A central part of this system is the medial prefrontal cortex, in particular the anterior paracingulate cortex. The reward as well as the mentalizing system is engaged in economic decision-making. We will discuss implications of this study for neuromarketing as well as general implications of these results that may help to provide deeper insights into the motivating forces of human behaviour.

  11. Religion, health and medicine in African Americans: implications for physicians.

    PubMed

    Levin, Jeff; Chatters, Linda M; Taylor, Robert Joseph

    2005-02-01

    Recent years have seen a burgeoning of research and writing on the connections between religion and health. The very best of this work comes from epidemiologic studies of African Americans. This paper summarizes results of these investigations, including findings identifying effects of religious participation on both physical and mental health outcomes. Evidence mostly supports a protective religious effect on morbidity and mortality and on depressive symptoms and overall psychological distress among African Americans. This paper also carefully discusses what the results of these studies mean and do not mean, an important consideration due to frequent misinterpretations of findings on this topic. Because important distinctions between epidemiologic and clinical studies tend to get glossed over, reports of religion-health associations oftentimes draw erroneous conclusions that foster unrealistic expectations about the role of faith and spirituality in health and healing. Finally, implications are discussed for clinical practice, medical education and public health.

  12. ENDOCANNABINOID INFLUENCE IN DRUG REINFORCEMENT, DEPENDENCE AND ADDICTION-RELATED BEHAVIORS

    PubMed Central

    Serrano, Antonia; Parsons, Loren H.

    2011-01-01

    The endogenous cannabinoid system is an important regulatory system involved in physiological homeostasis. Endocannabinoid signaling is known to modulate neural development, immune function, metabolism, synaptic plasticity and emotional state. Accumulating evidence also implicates brain endocannabinoid signaling in the etiology of drug addiction which is characterized by compulsive drug seeking, loss of control in limiting drug intake, emergence of a negative emotional state in the absence of drug use and a persistent vulnerability toward relapse to drug use during protracted abstinence. In this review we discuss the effects of drug intake on brain endocannabinoid signaling, evidence implicating the endocannabinoid system in the motivation for drug consumption, and drug-induced alterations in endocannabinoid function that may contribute to various aspects of addiction including dysregulated synaptic plasticity, increased stress responsivity, negative affective states, drug craving and relapse to drug taking. Current knowledge of genetic variants in endocannabinoid signaling associated with addiction is also discussed. PMID:21798285

  13. Collective Psychological Ownership and Intergroup Relations

    PubMed Central

    Verkuyten, Maykel; Martinovic, Borja

    2017-01-01

    Whereas much social psychological research has studied the in-group and out-group implications of social categorization and collective identity (“we”), little research has examined the nature and relevance of collective psychological ownership (“ours”) for intergroup relations. We make a case for considering collective psychological ownership as an important source of intergroup tensions. We do so by integrating theory and research from various social sciences, and we draw out implications for future social psychological research on intergroup relations. We discuss collective psychological ownership in relation to the psychology of possessions, marking behavior, intergroup threats, outgroup exclusion, and in-group responsibility. We suggest that the social psychological processes discussed apply to a range of ownership objects (territory, buildings, cultural artifacts) and various intergroup settings, including international, national, and local contexts, and in organizations and communities. We conclude by providing directions for future research in different intergroup contexts. PMID:28937914

  14. Religion, health and medicine in African Americans: implications for physicians.

    PubMed Central

    Levin, Jeff; Chatters, Linda M.; Taylor, Robert Joseph

    2005-01-01

    Recent years have seen a burgeoning of research and writing on the connections between religion and health. The very best of this work comes from epidemiologic studies of African Americans. This paper summarizes results of these investigations, including findings identifying effects of religious participation on both physical and mental health outcomes. Evidence mostly supports a protective religious effect on morbidity and mortality and on depressive symptoms and overall psychological distress among African Americans. This paper also carefully discusses what the results of these studies mean and do not mean, an important consideration due to frequent misinterpretations of findings on this topic. Because important distinctions between epidemiologic and clinical studies tend to get glossed over, reports of religion-health associations oftentimes draw erroneous conclusions that foster unrealistic expectations about the role of faith and spirituality in health and healing. Finally, implications are discussed for clinical practice, medical education and public health. PMID:15712787

  15. Recognition for Positive Behavior as a Critical Youth Development Construct: Conceptual Bases and Implications on Youth Service Development

    PubMed Central

    Law, Ben M. F.; Siu, Andrew M. H.; Shek, Daniel T. L.

    2012-01-01

    Recognition for positive behavior is an appropriate response of the social environment to elicit desirable external behavior among the youth. Such positive responses, rendered from various social systems, include tangible and intangible reinforcements. The following theories are used to explain the importance of recognizing positive behavior: operational conditioning, observational learning, self-determination, and humanistic perspective. In the current work, culturally and socially desirable behaviors are discussed in detail with reference to Chinese adolescents. Positive behavior recognition is especially important to adolescent development because it promotes identity formation as well as cultivates moral reasoning and social perspective thinking from various social systems. The significance of recognizing positive behavior is illustrated through the support, tutorage, invitation, and subsidy provided by Hong Kong's social systems in recognition of adolescent volunteerism. The practical implications of positive behavior recognition on youth development programs are also discussed in this work. PMID:22666155

  16. Use Of Transgenic Mice In UDP-Glucuronosyltransferase (UGT) Studies

    PubMed Central

    Ou, Zhimin; Huang, Min; Zhao, Lizi; Xie, Wen

    2009-01-01

    Transgenic mouse models are useful to understand the function and regulation of drug metabolizing enzymes in vivo. This article is intended to describe the general strategies and to discuss specific examples on how to use transgenic, gene knockout, and humanized mice to study the function as well as genetic and pharmacological regulation of UDP-glucuronosyltransferases (UGTs). The physiological and pharmacological implications of transcription factor-mediated UGT regulation will also be discussed. The UGT-regulating transcription factors to be discussed in this article include nuclear hormone receptors (NRs), aryl hydrocarbon receptor (AhR), and nuclear factor erythroid 2-related factor 2 (Nrf2). PMID:20070245

  17. Education and European integration

    NASA Astrophysics Data System (ADS)

    Lowe, John

    1992-11-01

    The main purpose of this article is to discuss the implications for education and training of the movement towards integration in Europe in the historic context of the creation of a single market within the European Community (EC) and the end of the Communist regimes in Central and Eastern Europe. The experience of the EC is used to illustrate trends and problems in the development of international cooperation in education and training. Common concerns and priorities throughout the new Europe are then identified and discussed. These include the pursuit of quality in schooling, efforts to serve the interests of disadvantaged learners, and the treatment of European Studies in the curriculum, including the improvement of the teaching of foreign languages.

  18. Global biomass burning - Atmospheric, climatic, and biospheric implications

    NASA Technical Reports Server (NTRS)

    Levine, Joel S.

    1990-01-01

    Topics discussed at the March 1990 American Geophysical Union's Conference on biomass burning which was attended by more than 175 participants representing 19 countries are presented. Conference highlights include discussion of remote sensing data concerning biomass burning (BB), gaseous and particle emissions resulting from BB in the tropics, BB in temperate and boreal ecosystems, the historic and prehistoric perspectives on BB, BB and global budgets for carbon, nitrogen, and oxygen, and the BB and the greenhouse effect. Global estimates of annual amounts of biomass burning and of the resulting release of carbon to the atmosphere and the mean gaseous emission ratios for fires in wetlands, chaparral, and boreal ecosystems are given. An overview is presented of some conference discussions including global burning from 1850-1980, the global impact of biomass burning, the great Chinese/Soviet fire of 1987, and burning and biogenic emissions.

  19. Disease implication of hyper-Hippo signalling.

    PubMed

    Wang, Shu-Ping; Wang, Lan-Hsin

    2016-10-01

    The Hippo signalling pathway regulates cellular proliferation, apoptosis and differentiation, thus exerting profound effects on cellular homeostasis. Inhibition of Hippo signalling has been frequently implicated in human cancers, indicating a well-known tumour suppressor function of the Hippo pathway. However, it is less certain whether and how hyperactivation of the Hippo pathway affects biological outcome in living cells. This review describes current knowledge of the regulatory mechanisms of the Hippo pathway, mainly focusing on hyperactivation of the Hippo signalling nexus. The disease implications of hyperactivated Hippo signalling have also been discussed, including arrhythmogenic cardiomyopathy, Sveinsson's chorioretinal atrophy, Alzheimer's disease, amyotrophic lateral sclerosis and diabetes. By highlighting the significance of disease-relevant Hippo signalling activation, this review can offer exciting prospects to address the onset and potential reversal of Hippo-related disorders. © 2016 The Authors.

  20. Disease implication of hyper-Hippo signalling

    PubMed Central

    Wang, Shu-Ping

    2016-01-01

    The Hippo signalling pathway regulates cellular proliferation, apoptosis and differentiation, thus exerting profound effects on cellular homeostasis. Inhibition of Hippo signalling has been frequently implicated in human cancers, indicating a well-known tumour suppressor function of the Hippo pathway. However, it is less certain whether and how hyperactivation of the Hippo pathway affects biological outcome in living cells. This review describes current knowledge of the regulatory mechanisms of the Hippo pathway, mainly focusing on hyperactivation of the Hippo signalling nexus. The disease implications of hyperactivated Hippo signalling have also been discussed, including arrhythmogenic cardiomyopathy, Sveinsson's chorioretinal atrophy, Alzheimer's disease, amyotrophic lateral sclerosis and diabetes. By highlighting the significance of disease-relevant Hippo signalling activation, this review can offer exciting prospects to address the onset and potential reversal of Hippo-related disorders. PMID:27805903

  1. Ethical Issues of Predictive Genetic Testing for Diabetes

    PubMed Central

    Haga, Susanne B.

    2009-01-01

    With the rising number of individuals affected with diabetes and the significant health care costs of treatment, the emphasis on prevention is key to controlling the health burden of this disease. Several genetic and genomic studies have identified genetic variants associated with increased risk to diabetes. As a result, commercial testing is available to predict an individual's genetic risk. Although the clinical benefits of testing have not yet been demonstrated, it is worth considering some of the ethical implications of testing for this common chronic disease. In this article, I discuss several issues that should be considered during the translation of predictive testing for diabetes, including familial implications, improvement of risk communication, implications for behavioral change and health outcomes, the Genetic Information Nondiscrimination Act, direct-to-consumer testing, and appropriate age of testing. PMID:20144329

  2. Recruitment and Financing of Candidates To Study Overseas: Its Implications for Australia.

    ERIC Educational Resources Information Center

    Smart, Don

    Growing numbers of Malaysian students are going to Australia for overseas study. This paper begins with a discussion of Malaysia's New Economic Policy, whose provisions include a phasing out of English as the language of instruction in favor of Bahasa Malaya, the language of the indigenous Malay majority. This policy provides a background for the…

  3. How Research Can Change the Researcher: The Need for Sensitivity, Flexibility and Ethical Boundaries in Conducting Qualitative Research in Counselling/Psychotherapy.

    ERIC Educational Resources Information Center

    Grafanaki, Soti

    1996-01-01

    Shares the experiences of a researcher engaged in qualitative research. Looks at researcher sensitivity and flexibility, ethical dilemmas, and the importance of a good "research alliance" with participants. Discusses, the implications of including participants as collaborators and the role of co-researchers. Emphasizes the impact of…

  4. New Directions in Mass Communications Policy: Implications for Citizen Education and Participation.

    ERIC Educational Resources Information Center

    Rothstein, Larry

    This paper, the second in a series of five on the current state of citizen education, focuses on mass communication. The following topics are discussed: communications today; the system of freedom of expression; social science research on the media (includes the audience and public information); minorities and the media; public broadcasting;…

  5. Scholarly Communication and Information Technology: Exploring the Impact of Changes in the Research Process on Archives. Rand Reprints.

    ERIC Educational Resources Information Center

    Michelson, Avra; Rothenberg, Jeff

    1993-01-01

    The report considers the interaction of trends in information technology and trends in research practices and the policy implications for archives. The information is divided into 4 sections. The first section, an "Overview of Information Technology Trends," discusses end-user computing, which includes ubiquitous computing, end-user…

  6. Beyond Google: The Invisible Web in the Academic Library

    ERIC Educational Resources Information Center

    Devine, Jane; Egger-Sider, Francine

    2004-01-01

    This article analyzes the concept of the Invisible Web and its implication for academic librarianship. It offers a guide to tools that can be used to mine the Invisible Web and discusses the benefits of using the Invisible Web to promote interest in library services. In addition, the article includes an expanded definition, a literature review,…

  7. Civil Defense, U. S. A.: A Programmed Orientation to Civil Defense. Unit 3. Natural Disasters.

    ERIC Educational Resources Information Center

    Defense Civil Preparedness Agency (DOD), Battle Creek, MI.

    The effects of natural disasters and the implications which those effects have for community emergency preparedness are discussed. Major topics include: (1) Similarities and differences in types of responses required by a nuclear and natural disasters, (2) The civil defense function in natural disasters, (3) Vulnerability analysis, (4) Warning…

  8. Science and Its Discontents: An Evolutionary Tale. Research & Occasional Papers Series. CSHE.11.2008

    ERIC Educational Resources Information Center

    Kennedy, Donald

    2008-01-01

    This paper analyzes the roots and implications of conflict between the conduct of science and government predilections in the United States, including the security state and neoconservative control of Washington. Three major conflicts are discussed: the emergence of new security and secrecy regimes that seek control of science; religiously derived…

  9. Experimental interstellar organic chemistry - Preliminary findings

    NASA Technical Reports Server (NTRS)

    Khare, B. N.; Sagan, C.

    1973-01-01

    Review of the results of some explicit experimental simulation of interstellar organic chemistry consisting in low-temperature high-vacuum UV irradiation of condensed simple gases known or suspected to be present in the interstellar medium. The results include the finding that acetonitrile may be present in the interstellar medium. The implication of this and other findings are discussed.

  10. Why People Don't Listen to Warnings: With Discussion of Implications for Futurists.

    ERIC Educational Resources Information Center

    Koster, Fran

    The document reviews recent literature on warning processes, evaluates the effectiveness of warnings in changing public policy and personal behavior, and applies warning literature to specific problem areas. Warning is interpreted to include a statement of the problem and a proposed course of action. The document is presented in six parts. Part…

  11. Virus-Like Ideas: The Role of Counselors in the Ecology of the Ideosphere.

    ERIC Educational Resources Information Center

    Carey, John C.; Lanning, Wayne L.

    1991-01-01

    Develops an analogy between viruses and ideas. Suggests that ideas, like viruses, can invade and infect us and that immune systems need to be developed to prevent future infection of destructive ideas. Discusses implications of the virus-idea analogy for the counseling profession, including counselors' susceptibility to infectious ideas which they…

  12. Aiming Talent Development toward Creative Eminence in the 21st Century

    ERIC Educational Resources Information Center

    Olszewski-Kubilius, Paula; Subotnik, Rena F.; Worrell, Frank C.

    2016-01-01

    Much has been written about the social and scientific problems that face the world in the 21st century, including climate change and economic inequality. In this context, the development of talented individuals who can tackle these problems is most important. In this article, the authors discuss the implications of 21st-century challenges for the…

  13. Emissions from ships

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Corbett, J.J.; Fischbeck, P.

    1997-10-31

    Recently the International Maritime Organization has made the first attempt to address air pollution from ships. This article presents information showing that ships are a significant source of air pollution on a global scale and discusses the policy implications of such a finding. The air pollution components included in the survey were NOx, SO2, CO2. 34 refs., 1 fig., 2 tabs.

  14. Actual Risk and Perceived Risk: Implications for Teaching Judgement and Decision-Making to Leaders.

    ERIC Educational Resources Information Center

    Guthrie, Steven P.

    This paper begins by presenting three tests, which are included in the appendix, of one's awareness of physical risks. This exercise leads to a discussion of the differences between actual and perceived risk, why people participate in outdoor activities, and the inaccurate perception of actual risks. Complicating the issue of accurately perceiving…

  15. Implications of Motivating Operations for the Functional Analysis of Consumer Choice

    ERIC Educational Resources Information Center

    Fagerstrom, Asle; Foxall, Gordon R.; Arntzen, Erik

    2010-01-01

    The present article introduces the concept of Motivating Operation (MO) to the context of consumer choice and discusses the function of the concept of MO in the context of the Behavioral Perspective Model (BPM). Including MO as part of the consumer behavior setting leads to a more comprehensive analysis and, as a result, improves our understanding…

  16. End User Information Searching on the Internet: How Do Users Search and What Do They Search For? (SIG USE)

    ERIC Educational Resources Information Center

    Saracevic, Tefko

    2000-01-01

    Summarizes a presentation that discussed findings and implications of research projects using an Internet search service and Internet-accessible vendor databases, representing the two sides of public database searching: query formulation and resource utilization. Presenters included: Tefko Saracevic, Amanda Spink, Dietmar Wolfram and Hong Xie.…

  17. Content analysis and thematic analysis: Implications for conducting a qualitative descriptive study.

    PubMed

    Vaismoradi, Mojtaba; Turunen, Hannele; Bondas, Terese

    2013-09-01

    Qualitative content analysis and thematic analysis are two commonly used approaches in data analysis of nursing research, but boundaries between the two have not been clearly specified. In other words, they are being used interchangeably and it seems difficult for the researcher to choose between them. In this respect, this paper describes and discusses the boundaries between qualitative content analysis and thematic analysis and presents implications to improve the consistency between the purpose of related studies and the method of data analyses. This is a discussion paper, comprising an analytical overview and discussion of the definitions, aims, philosophical background, data gathering, and analysis of content analysis and thematic analysis, and addressing their methodological subtleties. It is concluded that in spite of many similarities between the approaches, including cutting across data and searching for patterns and themes, their main difference lies in the opportunity for quantification of data. It means that measuring the frequency of different categories and themes is possible in content analysis with caution as a proxy for significance. © 2013 Wiley Publishing Asia Pty Ltd.

  18. [Sexual health and intellectual disability: a narrative literature review and its implications for nursing practice.

    PubMed

    Pariseau-Legault, Pierre; Holmes, Dave

    2017-09-01

    Issues associated with affectivity and sexuality in the context of intellectual disability have recently been the subject of various interdisciplinary discussions in academia. In nursing, interventions in sexual health are supported with hesitation and those issues constitute a marginal field of nursing research. A narrative literature review was realized in order to establish a portrait of the knowledge produced on this topic in the last decade. This paper illustrates three specific research areas recently developed, namely issues related to sexual autonomy, contextual factors positively or negatively contributing to emotional and sexual life, and the experiences of people identified as having an intellectual disability in this regard. On the basis of these results, different issues related to sexuality and intellectual disability are discussed, including those associated with the negotiation process of affective and sexual life, parenthood as a mediator of emotional and sexual expression, and the inclusiveness issues of sexual diversity in health interventions. Implications for nursing are finally discussed in light of the recent development of its role in sexual health.

  19. Teacher-student relationship climate and school outcomes: implications for educational policy initiatives.

    PubMed

    Barile, John P; Donohue, Dana K; Anthony, Elizabeth R; Baker, Andrew M; Weaver, Scott R; Henrich, Christopher C

    2012-03-01

    In recent discussions regarding concerns about the academic achievement of US students, educational policy makers have suggested the implementation of certain teacher policies. To address the limited empirical research on the putative educational impact of such policies, this study used multilevel structural equation models to investigate the longitudinal associations between teacher evaluation and reward policies, and student mathematics achievement and dropout with a national sample of students (n = 7,779) attending one of 431 public high schools. The student sample included an equal number of boys and girls averaging 16 years of age, and included a White (53%) majority. This study examined whether associations between teacher policies and student achievement were mediated by the teacher-student relationship climate. Results of this study were threefold. First, teacher evaluation policies that allowed students to evaluate their teachers were associated with more positive student reports of the classroom teaching climate. Second, schools with teacher reward policies that included assigning higher performing teachers with higher performing students had a negative association with student perceptions of the teaching climate. Lastly, schools with better student perceptions of the teaching climate were associated with lower student dropout rates by students' senior year. These findings are discussed in light of their educational policy implications.

  20. Vascular anomalies: classification, imaging characteristics and implications for interventional radiology treatment approaches

    PubMed Central

    Prajapati, H J S; Martin, L G; Patel, T H

    2014-01-01

    The term vascular anomaly represents a broad spectrum of vascular pathology, including proliferating vascular tumours and vascular malformations. While the treatment of most vascular anomalies is multifactorial, interventional radiology procedures, including embolic therapy, sclerotherapy and laser coagulation among others, are playing an increasingly important role in vascular anomaly management. This review discusses the diagnosis and treatment of common vascular malformations, with emphasis on the technique, efficacy and complications of different interventional radiology procedures. PMID:24588666

  1. The interdependence of the Rho GTPases and apicobasal cell polarity.

    PubMed

    Mack, Natalie Ann; Georgiou, Marios

    2014-01-01

    Signaling via the Rho GTPases provides crucial regulation of numerous cell polarization events, including apicobasal (AB) polarity, polarized cell migration, polarized cell division and neuronal polarity. Here we review the relationships between the Rho family GTPases and epithelial AB polarization events, focusing on the 3 best-characterized members: Rho, Rac and Cdc42. We discuss a multitude of processes that are important for AB polarization, including lumen formation, apical membrane specification, cell-cell junction assembly and maintenance, as well as tissue polarity. Our discussions aim to highlight the immensely complex regulatory mechanisms that encompass Rho GTPase signaling during AB polarization. More specifically, in this review we discuss several emerging common themes, that include: 1) the need for Rho GTPase activities to be carefully balanced in both a spatial and temporal manner through a multitude of mechanisms; 2) the existence of signaling feedback loops and crosstalk to create robust cellular responses; and 3) the frequent multifunctionality that exists among AB polarity regulators. Regarding this latter theme, we provide further discussion of the potential plasticity of the cell polarity machinery and as a result the possible implications for human disease.

  2. Media, social networking, and pediatric obesity.

    PubMed

    Vandewater, Elizabeth A; Denis, Laurence M

    2011-12-01

    The 5 years leading up to 2011 witnessed unprecedented transformations in the technology and media available to American consumers. These changes have led to major paradigmatic shifts in the way people think about media, how they use it, and the role they expect it to play in their lives. This article discusses the new media landscape and summarizes the evidence regarding media influences on pediatric obesity. Various effects on pediatric obesity are discussed and some conclusions and implications are provided, including possibilities and future directions for clinical practice and research. Copyright © 2011. Published by Elsevier Inc.

  3. Genetics of Aggression in Voles

    PubMed Central

    Gobrogge, Kyle L.; Wang, Zuoxin

    2016-01-01

    Prairie voles (Microtus ochrogaster) are socially monogamous rodents that form pair bonds—a behavior composed of several social interactions including attachment with a familiar mate and aggression toward conspecific strangers. Therefore, this species has provided an excellent opportunity for the study of pair bonding behavior and its underlying neural mechanisms. In this chapter, we discuss the utility of this unique animal model in the study of aggression and review recent findings illustrating the neurochemical mechanisms underlying pair bonding-induced aggression. Implications of this research for our understanding of the neurobiology of human violence are also discussed. PMID:22078479

  4. NGSS and the Next Generation of Science Teachers

    NASA Astrophysics Data System (ADS)

    Bybee, Rodger W.

    2014-03-01

    This article centers on the Next Generation Science Standards (NGSS) and their implications for teacher development, particularly at the undergraduate level. After an introduction to NGSS and the influence of standards in the educational system, the article addresses specific educational shifts—interconnecting science and engineering practices, disciplinary core ideas, crosscutting concepts; recognizing learning progressions; including engineering; addressing the nature of science, coordinating with Common Core State Standards. The article continues with a general discussion of reforming teacher education programs and a concluding discussion of basic competencies and personal qualities of effective science teachers.

  5. Hermaphroditus in Greco-Roman myth: lessons and hypotheses for intersex today.

    PubMed

    Jospe, Nicholas; Florence, Monica

    2004-11-01

    This discussion reviews the Greco-Roman mythic origins of the eponymic Hermaphroditus. It reviews the two major tales, one Greek, the other from Ovid, regarding the origins of the sexual and gender predicament of Hermaphroditus. It explains the genealogy of Hermaphroditus in Greek mythology, and includes a discussion of Ovid's text on Hermaphroditus. A comparison of the two renditions offers the opportunity to reflect on who Hermaphroditus may have been, and to reflect on the implications of his nature. The discussion also attends to some of the ethical and emotional conflicts for the intersexed today. Finally, the discussion explores whether lessons from, and hypotheses regarding a mythic figure, such as Hermaphroditus, may provide guidance for intersexed individuals and their parents.

  6. Overview and Implications of the Surgeon General's Report on Mental Health. Topical Discussion.

    ERIC Educational Resources Information Center

    Katz-Leavy, Judy; Bornemann, Thomas; Burns, Barbara J.; Friedman, Robert; Jenson, Peter; Osher, Trina

    This brief paper on a topical discussion session held at a conference on children's mental health about implications of the 1999 report, "Mental Health: A Report of the Surgeon General," for children. The discussion focuses primarily on the chapter in the report specifically about children and mental health with comments by four individuals who…

  7. Reflecting on imagery: a clinical perspective and overview of the special issue of memory on mental imagery and memory in psychopathology.

    PubMed

    Hackmann, Ann; Holmes, Emily A

    2004-07-01

    The authors provide an overview of the papers in the special issue of Memory on mental imagery and memory in psychopathology. The papers address emotional, intrusive mental imagery across a range of psychological disorders including post-traumatic stress disorder (PTSD), agoraphobia, body dysmorphic disorder, mood disorders, and psychosis. They include work on information processing issues including modelling cravings, conditioning, and aversions, as well as imagery qualities such as vividness and emotionality. The overview aims to place the articles in a broader context and draw out some exciting implications of this novel work. It provides a clinical context to the recent growth in this area from a cognitive behavioural therapy (CBT) perspective. We begin with PTSD, and consider links to imagery in other disorders. The clinical implications stemming from this empirical work and from autobiographical memory theory are discussed. These include consideration of a variety of techniques for eliminating troublesome imagery, and creating healthy, realistic alternatives.

  8. Duchenne Muscular Dystrophy: a Survey of Perspectives on Carrier Testing and Communication Within the Family.

    PubMed

    Hayes, Brenna; Hassed, Susan; Chaloner, Jae Lindsay; Aston, Christopher E; Guy, Carrie

    2016-06-01

    Carrier testing is widely available for multiple genetic conditions, and several professional organizations have created practice guidelines regarding appropriate clinical application and the testing of minors. Previous research has focused on carrier screening, predictive testing, and testing for X-linked conditions. However, family perspectives on carrier testing for X-linked lethal diseases have yet to be described. In this study, we explored communication within the family about carrier testing and the perspectives of mothers of sons with an X-linked lethal disease, Duchenne muscular dystrophy (DMD). Twenty-five mothers of sons with DMD participated in an anonymous online survey. Survey questions included multiple choice, Likert scale, and open ended, short answer questions. Analysis of the multiple choice and Likert scale questions revealed that most mothers preferred a gradual style of communication with their daughters regarding risk status. In addition, most participants reported having consulted with a genetic counselor and found it helpful. Comparisons between groups, analyzed using Fisher's exact tests, found no differences in preferred style due to mother's carrier status or having a daughter. Thematic analysis was conducted on responses to open ended questions. Themes identified included the impact of family implications, age and maturity, and a desire for autonomy regarding the decision to discuss and undergo carrier testing with at-risk daughters, particularly timing of these discussions. Implications for genetic counseling practice are discussed.

  9. Ecohydrology of the different photosynthetic pathways and implication for sustainable agriculture

    NASA Astrophysics Data System (ADS)

    Porporato, A. M.; Bartlett, M. S., Jr.; Hartzell, S. R.

    2016-12-01

    We use a recently proposed model that can simulate the different photosynthetic pathways coupled to the soil-plant-atmosphere continuum (SPAC) to discuss their ecohydrological implications in relation to water use and plant water stress in both natural and agricultural ecosystems. Built around the classical C3 photosynthesis core model (light reactions and Calvin cycle), the model includes a simple CO2-pump parameterization for C4 plants and a circadian rhythm and carbon storage components for the CAM (Crassulacean Acid Metabolism) plants. Its architecture takes advantage of the interesting modularity in which photosynthesis evolved in geological times to provide a relatively simple but comprehensive framework to explore the advantages and tradeoffs in water energy and carbon fluxes of the three photosynthetic pathways under fluctuating environmental forcing. We calibrate the model with reference to a series of C3,C4 and CAM plants, and discuss the trade-offs in water use and plan productivity and the related impact on hydrologic fluxes and soil biogeochemistry. We also consider some important crop species to analyze the implications of choosing crops with different photosynthetic pathways to improve sustainability of agriculture and irrigation in semiarid systems.

  10. Bolzano`s Approach to the Paradoxes of Infinity: Implications for Teaching

    NASA Astrophysics Data System (ADS)

    Waldegg, Guillermina

    2005-08-01

    In this paper we analyze excerpts of Paradoxes of the Infinite, the posthumous work of Bernard Bolzano (1781-1848), in order to show that Georg Cantor‘s (1845-1918) approach to the problem of defining actual mathematical infinity is not the most natural. In fact, Bolzano‘s approach to the paradoxes of infinity is more intuitive, while remaining internally coherent. Bolzano‘s approach, however, had limitations. We discuss implications for teaching, which include a better understanding of the responses of students to situations involving actual mathematical infinity, for it is possible to draw a kind of parallel between these responses and Bolzano‘s reasoning.

  11. Learned-Helplessness Theory: Implications for Research in Learning Disabilities.

    ERIC Educational Resources Information Center

    Canino, Frank J.

    1981-01-01

    The application of learned helplessness theory to achievement is discussed within the context of implications for research in learning disabilities. Finally, the similarities between helpless children and learning disabled students in terms of problems solving and attention are discussed. (Author)

  12. Dealing with the long-term social implications of research.

    PubMed

    Fleischman, Alan; Levine, Carol; Eckenwiler, Lisa; Grady, Christine; Hammerschmidt, Dale E; Sugarman, Jeremy

    2011-05-01

    Biomedical and behavioral research may affect strongly held social values and thereby create significant controversy over whether such research should be permitted in the first place. Institutional review boards (IRBs) responsible for protecting the rights and welfare of participants in research are sometimes faced with review of protocols that have significant implications for social policy and the potential for negative social consequences. Although IRB members often raise concerns about potential long-term social implications in protocol review, federal regulations strongly discourage IRBs from considering them in their decisions. Yet IRBs often do consider the social implications of research protocols and sometimes create significant delays in initiating or even prevent such research. The social implications of research are important topics for public scrutiny and professional discussion. This article examines the reasons that the federal regulations preclude IRBs from assessing the social risks of research, and examines alternative approaches that have been used with varying success by national advisory groups to provide such guidance. The article concludes with recommendations for characteristics of a national advisory group that could successfully fulfill this need, including sustainability, independence, diverse and relevant expertise, and public transparency.

  13. Enhancing Student Recruitment: A Theory for Understanding and Changing Student Decisions. AIR 1991 Annual Forum Paper.

    ERIC Educational Resources Information Center

    Pryor, Brandt W.

    This paper presents a theoretical discussion of how students make educational behavior decisions including attending a given institution, transferring, or dropping out. The theory is seen to apply to students of all ages and both sexes with implications for all areas of postsecondary education. The theory holds that educational decisions are based…

  14. The patient as partner: a competitive strategy in health care marketing.

    PubMed

    MacStravic, S

    1988-01-01

    The idea of the patient as partner incorporates a perspective that involves the patient in the care experience for explicit and important purposes. This article includes discussions of patient contributions; quality of care; cost implications; patient and provider satisfaction; and marketing, facilitation, and evaluation of a program that is designed to involve the patient in the care experience.

  15. Reconsidering Meaning Making and Its Analytical Implications for Cultural Studies of Science Education

    ERIC Educational Resources Information Center

    Arnseth, Hans Christian; Krange, Ingeborg

    2013-01-01

    The discussion in this forum aims to push some of the ideas further and thus clarify some of the concepts used in the feature article. This includes a debate of the concepts of meaning making, procedural and conceptual learning experiences, the distinction between realism and constructivism in our research practice, and finally how to foster…

  16. The Ethanol Project: Exploring Alternative Energy with Role-Play and Writing

    ERIC Educational Resources Information Center

    Winter, Julia

    2013-01-01

    This article describes a project that includes a two-week series of researching, essay writing, and speaking lessons exploring the broader implications of using ethanol as a fuel. The author, a chemistry teacher, describes how she uses a senate hearing discussion of ethanol fuel subsidies as the forum for a role-play. The four components of the…

  17. Symbolic Interactionism in Sociology of Education Textbooks in Mainland China: Coverage, Perspective and Implications

    ERIC Educational Resources Information Center

    Dong, Xuan

    2008-01-01

    17 textbooks are examined for the quantity and quality of their material pertaining to ideas in the symbolic interaction tradition. Most of the textbooks fail to discuss at least some of the ideas in this tradition. In the 5 exceptions, the texts only include material from the Chicago school of this tradition with only a little inclusive…

  18. The Scientist's World

    PubMed Central

    Davis, Bernard D.

    2000-01-01

    This paper describes the features of the world of science, and it compares that world briefly with that of politics and the law. It also discusses some “postmodern” trends in philosophy and sociology that have been undermining confidence in the objectivity of science and thus have contributed indirectly to public mistrust. The paper includes broader implications of interactions of government and science. PMID:10704471

  19. Rotation Criteria and Hypothesis Testing for Exploratory Factor Analysis: Implications for Factor Pattern Loadings and Interfactor Correlations

    ERIC Educational Resources Information Center

    Schmitt, Thomas A.; Sass, Daniel A.

    2011-01-01

    Exploratory factor analysis (EFA) has long been used in the social sciences to depict the relationships between variables/items and latent traits. Researchers face many choices when using EFA, including the choice of rotation criterion, which can be difficult given that few research articles have discussed and/or demonstrated their differences.…

  20. Protection motivation theory: is this a worthwhile theory for physical activity promotion?

    PubMed

    Plotnikoff, Ronald C; Trinh, Linda

    2010-04-01

    This article reviews the published studies in the physical activity domain, which include novel hypothesis from our laboratory, that have tested Rogers' Protection Motivation Theory. Across the various population groups, the theory's coping appraisal is generally supported; however, there is limited support for the theory's threat components. Implications of these findings are discussed from both theoretical and practical perspectives.

  1. Perspectives on Children's Navigation of the World Wide Web: Does the Type of Search Task Make a Difference?

    ERIC Educational Resources Information Center

    Bilal, Dania

    2002-01-01

    Reports findings of a three-part research project that examined the information seeking behavior and success of 22 seventh-grade science students in using the Web. Discusses problems encountered, including inadequate knowledge of how to use the search engine and poor level of research skills; and considers implications for Web training and system…

  2. Digital Semaphore: Tactical Implications of QR Code Optical Signaling for Fleet Communications

    DTIC Science & Technology

    2013-06-01

    Emissions Control (EMCON) and Hazards of Electromagnetic Radiation to Ordnance (HERO) restrict the ability for Naval Vessels to communicate using...importance of visual communications methods is brought to light by discussing emissions control, hazards of electromagnetic radiation to ordnance , and...overview of emissions restrictions including Emissions Control (EMCON) and Hazards of Electromagnetic Radiation to Ordnance (HERO). Chapter VII is

  3. Early Readers = Lo Que los padres necesitan saber sobre los...Lectores Precoces. What Parents Need To Know about...Series.

    ERIC Educational Resources Information Center

    Siegle, Del, Ed.

    This pamphlet (Practitioner's Guide), in both an English version and Spanish version, is intended for parents of precocious readers. Research facts on early reading are briefly summarized. Implications for the classroom and home are offered and include a discussion of early school entrance, principles of reading instruction, and ways the parent…

  4. Valuation of Drug Abuse: A Review of Current Methodologies and Implications for Policy Making

    ERIC Educational Resources Information Center

    Schori, Maayan

    2011-01-01

    This article reviews the use of several valuation methods as they relate to drug abuse and places them within the context of U.S. policy. First, cost-of-illness (COI) studies are reviewed and their limitations discussed. Second, three additional economic methods of valuing drug abuse are reviewed, including cost-effectiveness analysis (CEA),…

  5. Global Citizenship Education and Its Implications for Curriculum Goals at the Age of Globalization

    ERIC Educational Resources Information Center

    Zahabioun, Shahla; Yousefy, Alireza; Yarmohammadian, Mohammad H.; Keshtiaray, Narges

    2013-01-01

    As the inevitable process of the 21st century, globalization has affected and altered all aspects of human life including education. Therefore, one of the main tasks of any education system is to identify the features and impacts of such process. Thus, the present study was conducted aiming to discuss and examine global citizenship education and…

  6. Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas.

    PubMed

    Furukawa, Toru

    2007-01-01

    Intraductal papillary-mucinous neoplasms of the pancreas show characteristic clinicopathological and molecular pathobiological features which are distinct from those of conventional ductal adenocarcinomas. Alterations of KRAS, AKT/PKB, CDKN2A, TP53, SMAD4, STK11/LKB1, and DUSP6, and other molecular alterations, including global expression studies as well as their clinical implications, are discussed.

  7. Minimum Wage Laws: Who Benefits, Who Loses? Series on Public Issues No. 2.

    ERIC Educational Resources Information Center

    Hobson, Margaret Jane; Maurice, S. Charles

    It is the thesis of this booklet, one of a series intended to apply economic principles to major social and political issues of the day, that minimum wage laws actually hurt those whom such laws are designed to help. From this point of departure, separate subsections examine economic implications of minimum wage laws, including discussion of what…

  8. Proceedings of the National Silviculture Workshop: Silvicultural Implications Of Section 4, NFMA 1976; Flagstaff, Arizona; September 26-30, 1977

    Treesearch

    Gary Cargill; Robert Gillespie; Wayne Mann; Bob Blomquist; Don Strode; Edward R. Schneegas; Charles Sundstrom; John F. Corliss; Bill Pint; William D. Zeedyk; Robert D. Pfister; Raymond C. Shearer; Andrew A. Leven; Robert R. Alexander; Roger E. Sandquist; Robert E. Stevens; Clark Row; Jim Sabin; LaMont Engle; Tom Greathouse

    1977-01-01

    The 1977 Silviculture Workshop was held in Flagstaff, Arizona, September 26-30, 1977. The objective of the meeting was to discuss the reforestation and maintenance of appropriate forest cover required by Section 4 of the National Forest Management Act of 1976. These proceedings include the presentations that were available for publication.

  9. The human brain—from cells to society

    PubMed Central

    Hoogland, Eva; Patten, Iain; Berghmans, Stephane

    2013-01-01

    In December 2011, the European Science Foundation (ESF) brought together experts from a wide range of disciplines to discuss the issues that will influence the development of a healthier, more brain-aware European society. This perspective summarizes the main outcomes of that discussion and highlights important considerations to support improved mental health in Europe, including: The development of integrated neuropsychotherapeutic approaches to the treatment of psychiatric disorders.The development of more valid disease models for research into psychiatric disorders.An improved understanding of the relationship between biology and environment, particularly in relation to developmental plasticity and emerging pathology.More comparative studies to explore how scientific concepts relating to the human brain are received and understood in different sociocultural contexts.Research into the legal and ethical implications of recent developments in the brain sciences, including behavioral screening and manipulation, and emerging neurotechnologies. The broad geographical spread of the consulted experts across the whole of Europe, along with the wide range of disciplines they represent, gives these conclusions a strong scientific and pan-European endorsement. The next step will be to look closely into these five selected topics, in terms of research strategy, science policy, societal implications, and legal and ethical frameworks. PMID:23966920

  10. Professional data broadcasting: The new wave in pan-European information services

    NASA Astrophysics Data System (ADS)

    Castell, Stephen

    1989-05-01

    The background to and principles of data broadcasting are described. A review of customer usage of BBC Datacast in the U.K. is presented. Future developments are discussed, including the expansion of data broadcasting activities onto other transmission media including radio, cable and satellite channels, and the introduction of hybrid applications involving the interface of data broadcasting with traditional PTO and value-added networks. The European and international implications are reviewed together with a commentary on regulatory and legal considerations.

  11. Forecasting the Economic Impact of Future Space Station Operations

    NASA Technical Reports Server (NTRS)

    Summer, R. A.; Smolensky, S. M.; Muir, A. H.

    1967-01-01

    Recent manned and unmanned Earth-orbital operations have suggested great promise of improved knowledge and of substantial economic and associated benefits to be derived from services offered by a space station. Proposed application areas include agriculture, forestry, hydrology, public health, oceanography, natural disaster warning, and search/rescue operations. The need for reliable estimates of economic and related Earth-oriented benefits to be realized from Earth-orbital operations is discussed and recent work in this area is reviewed. Emphasis is given to those services based on remote sensing. Requirements for a uniform, comprehensive and flexible methodology are discussed. A brief review of the suggested methodology is presented. This methodology will be exercised through five case studies which were chosen from a gross inventory of almost 400 user candidates. The relationship of case study results to benefits in broader application areas is discussed, Some management implications of possible future program implementation are included.

  12. Economic consequences of commercial space operations

    NASA Technical Reports Server (NTRS)

    Stone, Barbara A.; Wood, Peter W.

    1990-01-01

    The potential economic benefits generated from increased industry involvement and investment in space activities and the subsequent cost implications are discussed. A historical overview of commercial industry involvement in space is given and sources of new economic growth in space are discussed. These include communications satellites, small satellites, positioning and navigation services, space transportation and infrastructure, remote sensing, and materials processing in space such as the manufacturing of protein crystals and zeolites. Macroeconomic trends and principles such as limits on technology trade, eased restrictions on international joint ventures, foreign investments in U.S. firms, and increased foreign competition are discussed. Earth observations and mapping are considered. Opportunities for private sector involvement in building space infrastructure and space transportation are highlighted.

  13. Ethical and Legal Issues in Biobanking for Genomic Research in Nigeria

    PubMed Central

    Akintola, Simisola. O.

    2013-01-01

    The pursuit of genomic research and biobanking has raised concerns and discussions about the ethical and legal implications. Given the specific challenges that surround such enterprise in low and middle income countries, it is pertinent to examine them in the light of the advent of Biobanking and Genomic research in Nigeria. In this paper I discuss the issues and suggest model solutions derived from advanced jurisdictions. These ethical and legal issues are discussed within the context of the legal system of a typical African country whose jurisprudence derives from that of its erstwhile colonial master, the United Kingdom. This includes issues relating to law and human rights, informed consent, native and customary law. PMID:24353984

  14. Helicopter noise regulations: An industry perspective

    NASA Technical Reports Server (NTRS)

    Wagner, R. A.

    1978-01-01

    A review of helicopter noise measurement programs and noise reduction/economic studies of FAA is given along with a critique of a study which addresses the economic impact of noise reduction on helicopter noise. Modification of several helicopters to reduce noise and demonstrate the economic impact of the application of the current state-of-the-art technology is discussed. Specific helicopters described include Boeing Vertol 347 Helicopter, Hughes OH-6 Helicopter, and Hughes 269C Helicopter. Other topics covered include: (1) noise trends and possible noise limits; (2) accuracy of helicopter noise prediction techniques; (3) limited change possibilities of derivatives; and (4) rotor impulsive noise. The unique operational capabilities of helicopters and the implications relative to noise regulations and certification are discussed.

  15. Medical Archives and Digital Culture

    PubMed Central

    Biernoff, Suzannah

    2012-01-01

    When BioShock was released in 2007, reviewers praised the moral complexities of the narrative and the game's dystopian vision of what Ayn Rand dubbed the “virtue of selfishness”. What critics overlooked was the extent to which the disturbingly realistic artwork and musical score relied on found images and sound, including a recording of distressed breathing from a physician's website, and digitised First World War medical photographs of soldiers with facial injuries. This article examines the implications of these acts of appropriation from a range of critical perspectives including Susan Sontag's commentary on the representation of suffering; recent literature on the ethics of computer games; and an online discussion forum in which players of BioShock discuss the moral “grey areas” of the game. PMID:27152120

  16. Genetics of rare mesenchymal tumors: implications for targeted treatment in DFSP, ASPS, CCS, GCTB and PEComa.

    PubMed

    Rutkowski, Piotr; Przybył, Joanna; Świtaj, Tomasz

    2014-08-01

    Soft tissue and bone sarcomas comprise a heterogeneous group of mesenchymal tumors that include roughly 130 distinct diagnostic entities. Many of them are exceptionally rare, with only few cases diagnosed worldwide each year. Development of novel targeted treatment in this group of tumors is of special importance since many sarcoma subtypes are resistant to conventional chemotherapy and the effective therapeutic options are limited. In this review we aim to discuss the molecular implications for targeted therapy in selected rare soft tissue and bone sarcoma subtypes, including dermatofibrosarcoma protuberans (DFSP), alveolar soft part sarcoma (ASPS), clear cell sarcoma (CCS), giant cell tumor of bone (GCTB) and perivascular epithelioid cell neoplasms (PEComas). This article is part of a Directed Issue entitled: Rare cancers. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Addressing the Needs of Preschool Children in the Context of Disasters and Terrorism: Clinical Pictures and Moderating Factors.

    PubMed

    Hamiel, Daniel; Wolmer, Leo; Pardo-Aviv, Lee; Laor, Nathaniel

    2017-07-01

    This paper surveys the existent theoretical and research literature regarding the needs of preschool children in the context of disasters and terrorism with the aim of understanding (a) the consequences of such events for young children and (b) the main moderating variables influencing the event-consequence association to learn how to enhance their resilience. Consequences include a variety of emotional, behavioral, and biological outcomes. Implications for refugee children are discussed. Main moderating variables were mother's sensitivity and mother's PTSD symptoms. Exposure to disasters and terrorism may have severe effects on the mental health and development among preschool children. Future research should explore the implications of different levels of exposure and the effects of moderating psychosocial and biological variables, including the parent-child triad, on the event-consequence relationship.

  18. African-American suicide: a cultural paradox.

    PubMed

    Gibbs, J T

    1997-01-01

    African-American suicide rates have traditionally been lower than White rates despite a legacy of racial discrimination, persistent poverty, social isolation, and lack of community resources. This paper focuses on four issues: (1) patterns and trends of Black suicide across the lifespan; (2) risk and protective factors in subgroups of Blacks; (3) the influence of cultural factors on suicide patterns of Blacks; and (4) implications of these patterns for prevention and early intervention of suicidal behavior among African Americans. Risk factors for Black suicide include: male sex, early adulthood, substance abuse, psychiatric disorders, family or interpersonal conflict, antisocial behavior, and homosexuality. Protective factors that mitigate the risks of suicide include religiosity, older age, southern residence, and social support. Implications for preventive policies and programs are discussed to counter the recent trend of rising suicide rates among adolescents and very elderly Blacks.

  19. Design requirements for SRB production control system. Volume 2: System requirements and conceptual description

    NASA Technical Reports Server (NTRS)

    1981-01-01

    In the development of the business system for the SRB automated production control system, special attention had to be paid to the unique environment posed by the space shuttle. The issues posed by this environment, and the means by which they were addressed, are reviewed. The change in management philosphy which will be required as NASA switches from one-of-a-kind launches to multiple launches is discussed. The implications of the assembly process on the business system are described. These issues include multiple missions, multiple locations and facilities, maintenance and refurbishment, multiple sources, and multiple contractors. The implications of these aspects on the automated production control system are reviewed including an assessment of the six major subsystems, as well as four other subsystem. Some general system requirements which flow through the entire business system are described.

  20. Evidence for social working memory from a parametric functional MRI study.

    PubMed

    Meyer, Meghan L; Spunt, Robert P; Berkman, Elliot T; Taylor, Shelley E; Lieberman, Matthew D

    2012-02-07

    Keeping track of various amounts of social cognitive information, including people's mental states, traits, and relationships, is fundamental to navigating social interactions. However, to date, no research has examined which brain regions support variable amounts of social information processing ("social load"). We developed a social working memory paradigm to examine the brain networks sensitive to social load. Two networks showed linear increases in activation as a function of increasing social load: the medial frontoparietal regions implicated in social cognition and the lateral frontoparietal system implicated in nonsocial forms of working memory. Of these networks, only load-dependent medial frontoparietal activity was associated with individual differences in social cognitive ability (trait perspective-taking). Although past studies of nonsocial load have uniformly found medial frontoparietal activity decreases with increasing task demands, the current study demonstrates these regions do support increasing mental effort when such effort engages social cognition. Implications for the etiology of clinical disorders that implicate social functioning and potential interventions are discussed.

  1. Implications of Telecommuting in a Library Environment.

    ERIC Educational Resources Information Center

    Meglio, Delores

    1991-01-01

    Discussion of telecommuting possibilities focuses on a program at Information Access Company that allows indexers and abstractors to work at home. Employer and employee expectations are discussed, equipment provisions are described, employee benefits are examined, and implications for the library environment are suggested. (LRW)

  2. Ethical implications of location and accelerometer measurement in health research studies with mobile sensing devices.

    PubMed

    Fuller, Daniel; Shareck, Martine; Stanley, Kevin

    2017-10-01

    Quantification of individual behaviours using mobile sensing devices, including physical activity and spatial location, is a rapidly growing field in both academic research and the corporate world. In this case study, we summarize the literature examining the ethical aspects of mobile sensing and argue that a robust discussion about the ethical implications of mobile sensing for research purposes has not occurred sufficiently in the literature. Based on our literature summary and guided by basic ethical principles set out in Canadian, US, and International Ethics documents we propose four areas where further discussion should occur: consent, privacy and confidentiality, mitigating risk, and consideration of vulnerable populations. We argue that ongoing consent is crucial for participants to be aware of the precision and volume of data that is collected with mobile sensing devices. Related to privacy we discuss that participants may not agree that anonymized data is sufficient for privacy and confidentiality when mobile sensing data are collected. There has been some discussion about mitigating risk in the literature. We highlight that the researchers' obligations toward mitigating risks that are not directly related to the study purpose are unclear and require considerable discussion. Finally, using mobile sensing devices to study vulnerable populations requires careful consideration, particularly with respect to balancing research needs with participant burden. Based on our discussion, we identify a broad set of unanswered questions about the ethics of mobile sensing that should be addressed by the research community. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Companion piece: Convention on the Rights of the Child special protection measures: overview of implications and value for children in the United States.

    PubMed

    Svevo-Cianci, Kimberly; Velazquez, Sonia C

    2010-01-01

    The United Nations Convention on the Rights of the Child (CRC) is an international treaty that commits ratifying states parties to uphold the rights of all children under the age of 18. This article discusses the issues of highest relevance to the United States and reviews the pros and cons of ratifying, from the perspective of the convention's intent and potential, sovereignty of states, and national public policies, and regarding the special protection recommended for particularly vulnerable children. Specific implementation issues discussed include training, accountability, and monitoring.

  4. Catastrophic disruption of asteriods and satellites; Proceedings of the International Workshop, Pisa, Italy, July 30-August 2, 1985

    NASA Astrophysics Data System (ADS)

    Davis, D. R.; Farinella, P.; Paolicchi, P.; Zappala, V.

    Theoretical, numerical, and experimental investigations of the violent disruption of asteroids or planetary satellites are discussed in reviews and reports. Topics examined include acceleration techniques and results of experiments simulating catastrophic fragmentation events; laboratory simulations of catastrophic impact; scaling laws for the catastrophic collisions of asteroids; asteroid collisional history, the origin of the Hirayama families, and disruption of small satellites; and the implications of the inferred compositions of a steroids for their collisional evolution. Diagrams, graphs, tables, and a summary of the discussion at the workshop are provided.

  5. Tailored program evaluation: Past, present, future.

    PubMed

    Suggs, L Suzanne; Cowdery, Joan E; Carroll, Jennifer B

    2006-11-01

    This paper discusses measurement issues related to the evaluation of computer-tailored health behavior change programs. As the first generation of commercially available tailored products is utilized in health promotion programming, programmers and researchers are becoming aware of the unique challenges that the evaluation of these programs presents. A project is presented that used an online tailored health behavior assessment (HBA) in a worksite setting. Process and outcome evaluation methods are described and include the challenges faced, and strategies proposed and implemented, for meeting them. Implications for future research in tailored program development, implementation, and evaluation are also discussed.

  6. Catastrophic disruption of asteriods and satellites; Proceedings of the International Workshop, Pisa, Italy, July 30-August 2, 1985

    NASA Technical Reports Server (NTRS)

    Davis, D. R. (Editor); Farinella, P. (Editor); Paolicchi, P. (Editor); Zappala, V. (Editor)

    1986-01-01

    Theoretical, numerical, and experimental investigations of the violent disruption of asteroids or planetary satellites are discussed in reviews and reports. Topics examined include acceleration techniques and results of experiments simulating catastrophic fragmentation events; laboratory simulations of catastrophic impact; scaling laws for the catastrophic collisions of asteroids; asteroid collisional history, the origin of the Hirayama families, and disruption of small satellites; and the implications of the inferred compositions of a steroids for their collisional evolution. Diagrams, graphs, tables, and a summary of the discussion at the workshop are provided.

  7. "Seems I'm not alone at being alone:" contributing factors and interventions for drinking games in the college setting.

    PubMed

    Kilmer, Jason R; Cronce, Jessica M; Logan, Diane E

    2014-09-01

    Alcohol use among college students is prevalent and sometimes takes the form of drinking games, in which players are required to drink in accordance with a set of pre-defined rules. Drinking games are typically associated with elevated alcohol consumption and risk to the individual. This perspective piece considers the potential role of social anxiety in motivating participation in drinking games, perceived norms surrounding drinking games (including ways they are portrayed and discussed in popular media), and the role of competitiveness. Implications for skills training-based prevention and intervention efforts are discussed.

  8. Moral orientation of elderly persons: considering ethical dilemmas in health care.

    PubMed

    Pinch, W J; Parsons, M E

    1997-09-01

    Knowledge about moral development and elderly persons is very limited. A hermeneutical interpretative study was conducted with healthy elderly persons (n = 20) in order to explore and describe their moral orientation based on the paradigms of justice (Kohlberg) and care (Gilligan). The types of moral reasoning, dominance, alignment and orientation were determined. All but one participant included both types of reasoning when discussing an ethical conflict. None of the men's moral reasoning was dominated by caring, but justice dominated the reasoning of four women. The implications for ethical decision-making and future research are discussed.

  9. Gentrification and urban children's well-being: tipping the scales from problems to promise.

    PubMed

    Formoso, Diana; N Weber, Rachel; S Atkins, Marc

    2010-12-01

    Gentrification changes the neighborhood and family contexts in which children are socialized-for better and worse-yet little is known about its consequences for youth. This review, drawn from research in urban planning, sociology, and psychology, maps out mechanisms by which gentrification may impact children. We discuss indicators of gentrification and link neighborhood factors, including institutional resources and collective socialization, to family processes more proximally related to child development. Finally, we discuss implications for intervention and public policy recommendations that are intended to tip the scales toward better outcomes for low-income youth in gentrifying areas.

  10. The search for intelligence

    NASA Astrophysics Data System (ADS)

    Coffey, E. J.

    1980-12-01

    Implications of current understandings of the nature of human intelligence for the possibility of extraterrestrial intelligence are discussed. The perceptual theory of intelligence as the manipulation of perceptual images rather than language is introduced, and conditions leading to the ascendancy of man over other hominids with similar conceptual abilities are discussed, including the liberation of the hands from a locomotive function and the evolution of neoteny. It is argued that the specificity of the environmental, behavioral and physiological conditions which lead to the emergence of technologically oriented, and communicative intelligent creatures suggests that any SETI would most likely be fruitless.

  11. Adoption research, practice, and societal trends: Ten years of progress.

    PubMed

    Wiley, Mary O'Leary

    2017-12-01

    Adoption involves the legal transfer of parental rights and responsibilities from a child's birth parents to adults who will raise the child (Reitz & Watson, 1992). Research related to adoption has expanded over the past 10 years and has incorporated more focus on implications for practice and public policy. This expansion has reflected increased awareness of the lived experience of adopted individuals, in addition to that of adoptive families and birth or first parents and families, collectively known as the adoption kinship network (Grotevant & McRoy, 1998). Trends discussed included research and social trends or movements (2007-2017) since the publication of the final article in a series of articles in the psychological literature related to adoption in The Counseling Psychologist (Baden & Wiley, 2007; Lee, 2003; O'Brien & Zamostny, 2003; Wiley & Baden, 2005; Zamostny, O'Brien, Baden, & Wiley, 2003; Zamostny, Wiley, O'Brien, Lee, & Baden, 2003). This article summarizes the social trends and research related to adoption over the last 10 years, including longitudinal and meta-analytic studies, increased research and conceptualization of ethnic and racial identity development, research on microaggressions, and research on diverse adoptive families, including those with gay and lesbian parents. Social trends included increased knowledge related to Internet accessibility, genetic information, continued focus on openness, and viewing adoption through a more critical lens. Implications are discussed for the development of programs that enhance competence of mental health professionals and adoption professionals in adoption-competent practice. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  12. The origin of comets - Implications for planetary formation

    NASA Technical Reports Server (NTRS)

    Weissman, P. R.

    1985-01-01

    Primordial and episodic theories for the origin of comets are discussed. The implications of the former type for the origin of the solar system are considered. Candidate sites for the formation of comets are compared. The possible existence of a massive inner Oort cloud is discussed.

  13. "He will ask why the child gets sick so often": the gendered dynamics of intra-household bargaining over healthcare for children with fever in the Volta Region of Ghana.

    PubMed

    Tolhurst, Rachel; Amekudzi, Yaa Peprah; Nyonator, Frank K; Bertel Squire, S; Theobald, Sally

    2008-03-01

    This paper explores the gendered dynamics of intra-household bargaining around treatment seeking for children with fever revealed through two qualitative research studies in the Volta Region of Ghana, and discusses the influence of different gender and health discourses on the likely policy implications drawn from such findings. Methods used included focus group discussions, in-depth and critical incidence interviews, and Participatory Learning and Action methods. We found that treatment seeking behaviour for children was influenced by norms of decision-making power and 'ownership' of children, access to and control over resources to pay for treatment, norms of responsibility for payment, marital status, household living arrangements, and the quality of relationships between mothers, fathers and elders. However, the implications of these findings may be interpreted from different perspectives. Most studies that have considered gender in relation to malaria have done so within a narrow biomedical approach to health that focuses only on the outcomes of gender relations in terms of the (non-)utilisation of allopathic healthcare. However, we argue that a 'gender transformatory' approach, which aims to promote women's empowerment, needs to include but go beyond this model, to consider broader potential outcomes of intra-household bargaining for women's and men's interests, including their livelihoods and 'bargaining positions'.

  14. Quality of life in survivors of a primary bone tumour: a systematic review.

    PubMed

    Eiser, C; Grimer, R J

    1999-01-01

    Purpose. We conducted a systematic search of published literature, to assess (i) quality of life (QoL) for survivors of a bone tumour compared with the normal population; (ii) QoL implications following amputation, successful or failed limb salvage; (iii) adaptation of young children to amputation compared with older children or adolescents.Methods. Electronic databases were searched including Medline, PsycLIT and Cinahl covering the years 1982- 1998.Results. We identified 11 studies. Regardless of treatment, physical functioning was poor compared with population norms or healthy siblings.There was less consistent evidence regarding emotional functioning. Seven studies compared functioning in amputees and limb salvage patients.Two reported advantages in physical function for the limb salvage group, one for the amputees and the rest no differences. Evidence about social functioning or marriage is inconclusive, but there are suggestions that amputees report more job discrimination.Discussion. The literature is inconclusive, largely because of methodological problems. These include small and non-representative samples, and lack of sensitive and appropriate measures. Specific gaps in the literature include very little work concerned with psychological outcomes for children, or for those experiencing failed limb salvage. More attention needs to be given to gender differences in emotional response to traumatic surgery.The implications of the results for helping families balance the merits of different treatments are discussed.

  15. Is prayer CAM?

    PubMed

    Tippens, Kim; Marsman, Kevin; Zwickey, Heather

    2009-04-01

    Alternative medicine researchers and policy makers have classified prayer as a mind-body intervention, and thus, a modality of complementary and alternative medicine (CAM). As such, numerous epidemiological surveys of CAM utilization-which have included prayer-depict increasing CAM use, particularly in specific racial and ethnic groups. This paper discusses the implications of conflating prayer and CAM, especially regarding the definitions of both concepts and the resulting statistics of CAM utilization.

  16. Salience of Tactile Cues: An Examination of Tactor Actuator and Tactile Cue Characteristics

    DTIC Science & Technology

    2015-08-01

    this burden estimate or any other aspect of this collection of information, including suggestions for reducing the burden, to Department of Defense ...patterns of tactile cue arrays, and some differences due to measurement approach. Implications for future research are discussed. 15. SUBJECT TERMS...results for tactor type, taction, and interaction term for the prediction of forced-choice preference ................................................21

  17. Human genome education model project. Ethical, legal, and social implications of the human genome project: Education of interdisciplinary professionals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weiss, J.O.; Lapham, E.V.

    1996-12-31

    This meeting was held June 10, 1996 at Georgetown University. The purpose of this meeting was to provide a multidisciplinary forum for exchange of state-of-the-art information on the human genome education model. Topics of discussion include the following: psychosocial issues; ethical issues for professionals; legislative issues and update; and education issues.

  18. Learning Strategies for Post-Literacy and Continuing Education in Mali, Niger, Senegal, and Upper Volta. UIE Studies on Post-Literacy and Continuing Education 2.

    ERIC Educational Resources Information Center

    Dave, R. H., Ed.; And Others

    This collection contains four papers discussing the outcomes of an international research project on the concept of lifelong education and its implications for educational reforms and development in developing nations. The following papers are included: "Rural Newspapers and Other Learning Strategies for Post-Literacy and Basic Education in…

  19. Issues/Higher Education/Institutional Research. NCAIR Proceedings. Fifth Annual Meeting of the North Carolina Association for Institutional Research (Asheville, North Carolina, November 2-3, 1977).

    ERIC Educational Resources Information Center

    Brown, Charles I., Ed.

    Proceedings from the fifth annual meeting of the North Carolina Association for Institutional Research (NCAIR) focus on issues affecting higher education and the relationship of these issues to the institutional research function. Included are general session addresses by Charles A. Lyons and Dick Robinson that discuss the implications of Judge…

  20. Social vs. Clinical Perspectives on the Use of Information: Implications for School-based Information Systems. Systemic Evaluation Project.

    ERIC Educational Resources Information Center

    Sirotnik, Kenneth A.; And Others

    This paper presents a study of the contrast of social and clinical perspectives on the selection and use of information by school staff, including: (1) an outline of the context and activities of the study; (2) a definition and discussion of the basic distinction between social and clinical perspectives; (3) an examination of case material…

  1. Modeling of Spark Gap Performance

    DTIC Science & Technology

    1983-06-01

    MODELING OF SPARK GAP PERFORMANCE* A. L. Donaldson, R. Ness, M. Hagler, M. Kristiansen Department of Electrical Engineering and L. L. Hatfield...gas pressure, and chaJ:ging rate on the voltage stability of high energy spark gaps is discussed. Implications of the model include changes in...an extremely useful, and physically reasonable framework, from which the properties of spark gaps under a wide variety of experimental conditions

  2. Purpose in Life: A Brief Review of the Literature and Its Implications for School Guidance Programs

    ERIC Educational Resources Information Center

    Yuen, Mantak; Lee, Queenie A. Y.; Kam, Jason; Lau, Patrick S. Y.

    2017-01-01

    Purpose in life has emerged as an important notion in positive psychology. It is regarded as a factor that can contribute to any individual's wellbeing. Based on a review of the literature, the authors discuss key issues that pertain to purpose in life, including how the construct is defined and conceptualised, its importance in living a…

  3. Copyright and the Teaching/Learning Process. Issues Analyzed at the Critical Issues Conference 4 (Washington, DC, March 21-23, 1977).

    ERIC Educational Resources Information Center

    Miller, Jerome K., Ed.

    The nine papers in this collection discuss the educational issues raised by the 1976 Copyright Revision Act with special emphasis on conflicts between the rights of teachers and learners and the rights of creators. Topics covered include: (1) the history of copyright development in Europe and America, (2) the educational implications of the new…

  4. Towards an ethically sensitive implementation of non invasive prenatal screening in the global context

    PubMed Central

    Mozersky, Jessica; Ravitsky, Vardit; Rapp, Rayna; Michie, Marsha; Chandrasekharan, Subhashini; Allyse, Megan

    2017-01-01

    Cell-free DNA (cfDNA) screening is an emerging prenatal technology available in 90 countries. Despite its rapid global diffusion, there is a gap in knowledge about its implementation outside of North America and Europe including low to middle income countries. To address this, we organized an international comparative workshop to explore the ethical and social implications of the global expansion of cfDNA screening. We describe 8 key insights that arose from discussions to illustrate how bioethical discussions and normative frameworks that originate and reflect North American and European ethical priorities can be enriched by attending to the importance of local context. The utility and ethical implications of cfDNA screening are highly variable and dependent upon local healthcare systems, cultural, economic, and socio-political contexts and needs. We call for a more subtle, dynamic and contextual understanding of the international spread of cfDNA screening, which will evoke diverse challenges across different contexts. PMID:28301696

  5. Rotors and the Dynamics of Cardiac Fibrillation

    PubMed Central

    Pandit, Sandeep V.; Jalife, José

    2013-01-01

    The objective of this article is to present a broad review on the role of cardiac electrical rotors and their accompanying spiral waves in the mechanism of cardiac fibrillation. At the outset, we present a brief historical overview regarding reentry, and then discuss the basic concepts and terminologies pertaining to rotors and their initiation. Thereafter, the intrinsic properties of rotors and spiral waves, including phase singularities, wavefront curvature and dominant frequency maps are discussed. The implications of rotor dynamics for the spatio-temporal organization of fibrillation, independent of the species being studied are touched upon next. The knowledge gained regarding the role of cardiac structure in the initiation and/or maintenance of rotors and the ionic bases of spiral waves in the last two decades, and its significance for drug therapy is reviewed subsequently. We conclude by looking at recent evidence suggesting that rotors are critical in sustaining both atrial and ventricular fibrillation (AF, VF) in the human heart, and its implications for treatment with radio-frequency ablation. PMID:23449547

  6. Workplace practices with mental health implications impacting on recruitment and retention of overseas nurses in the context of nursing shortages.

    PubMed

    Omeri, Akram

    2006-01-01

    In response to nursing workforce shortages, health agencies in Australia and elsewhere have sought to meet the demand for nursing services by recruiting nurses internationally. While there is a major focus on recruitment, little attention is given to factors that could enhance retention of overseas qualified nurses. There are a host of factors reported in the literature that impact upon retention of overseas nurses in the workforce, including: impact of re-settlement experiences in the new country; discriminatory practices in accessing employment and negative experiences in the work place. For the benefit of long term retention of overseas nurse graduates in the workforce in Australia and globally, these experiences are major issues needing urgent attention. This discussion paper reviews the literature to explore the impact of aggression and discriminatory practices in nursing as evidence for nurses leaving the profession, and discusses the mental health implications and consequences of such practices relating to overseas nurse graduates.

  7. The Neuropsychology of Risky Sexual Behavior

    PubMed Central

    Ross, J. Megan; Duperrouzel, Jacqueline; Vega, Melanie; Gonzalez, Raul

    2017-01-01

    Objective Engagement in risky sexual behavior (RSB) is a significant public health concern. A growing body of literature is elucidating the role of brain systems and neuropsychological constructs implicated in RSB, which may pave the way for novel insights and prevention efforts. Methods In this article, we review studies incorporating neuropsychology into the study of RSB across the lifespan. The review of the literature on the neuropsychology of RSB is separated into three different sections by age of participants. Background is presented on research associating RSB with neurocognitive processes and the brain systems involved. Given the overlap between RSBs and substance use, studies addressing these problems in tandem are also discussed. Results Neurocognitive constructs are implicated in RSB, including impulsivity, decision-making, and working memory. Discussion Thus far, evidence suggest that neuropsychological factors are associated with engagement in RSB. More research on the influence of neuropsychological factors on engagement in RSB is necessary and may help inform future prevention efforts. PMID:27173086

  8. Rehabilitation treatment taxonomy: implications and continuations.

    PubMed

    P Dijkers, Marcel; Hart, Tessa; Whyte, John; M Zanca, Jeanne; Packel, Andrew; Tsaousides, Theodore

    2014-01-01

    In relation to the conceptual framework for a rehabilitation treatment taxonomy (RTT), which has been proposed in other articles in this supplement, this article discusses a number of issues relevant to its further development, including creating distinctions within the major target classes; the nature and quantity of allowable targets of treatment; and bracketing as a way of specifying (1) the skill or knowledge taught; (2) the nature of compensation afforded by changes in the environment, assistive technology, and orthotics/prosthetics; and (3) the ingredients in homework a clinician assigns. Clarification is provided regarding the role of the International Classification of Functioning, Disability and Health, focusing a taxonomy on ingredients versus other observable aspects of treatment, and regarding our lack of knowledge and its impact on taxonomy development. Finally, this article discusses the immediate implications of the work to date and presents the need for rehabilitation stakeholders of all disciplines to be involved in further RTT development. Copyright © 2014 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  9. Targeting the hallmarks of cancer with therapy-induced endoplasmic reticulum (ER) stress

    PubMed Central

    Garg, Abhishek D; Maes, Hannelore; van Vliet, Alexander R; Agostinis, Patrizia

    2015-01-01

    The endoplasmic reticulum (ER) is at the center of a number of vital cellular processes such as cell growth, death, and differentiation, crosstalk with immune or stromal cells, and maintenance of proteostasis or homeostasis, and ER functions have implications for various pathologies including cancer. Recently, a number of major hallmarks of cancer have been delineated that are expected to facilitate the development of anticancer therapies. However, therapeutic induction of ER stress as a strategy to broadly target multiple hallmarks of cancer has been seldom discussed despite the fact that several primary or secondary ER stress-inducing therapies have been found to exhibit positive clinical activity in cancer patients. In the present review we provide a brief historical overview of the major discoveries and milestones in the field of ER stress biology with important implications for anticancer therapy. Furthermore, we comprehensively discuss possible strategies enabling the targeting of multiple hallmarks of cancer with therapy-induced ER stress. PMID:27308392

  10. Shot noise cross-correlation functions and cross spectra - Implications for models of QPO X-ray sources

    NASA Technical Reports Server (NTRS)

    Shibazaki, N.; Elsner, R. F.; Bussard, R. W.; Ebisuzaki, T.; Weisskopf, M. C.

    1988-01-01

    The cross-correlation functions (CCFs) and cross spectra expected for quasi-periodic oscillation (QPO) shot noise models are calculated under various assumptions, and the results are compared to observations. Effects due to possible coherence of the QPO oscillations are included. General formulas for the cross spectrum, the cross-phase spectrum, and the time-delay spectrum for QPO shot models are calculated and discussed. It is shown that the CCFs, cross spectra, and power spectra observed for Cyg X-e2 imply that the spectrum of the shots evolves with time, with important implications for the interpretation of these functions as well as of observed average energy spectra. The possible origins for the observed hard lags are discussed, and some physical difficulties for the Comptonization model are described. Classes of physical models for QPO sources are briefly addressed, and it is concluded that models involving shot formation at the surface of neutron stars are favored by observation.

  11. Model of Reconnection of Weakly Stochastic Magnetic Field and its Implications

    NASA Astrophysics Data System (ADS)

    Lazarian, A.; Vishniac, E. T.

    2009-08-01

    We discuss the model of magnetic field reconnection in the presence of turbulence introduced by us ten years ago. The model does not require any plasma effects to be involved in order to make the reconnection fast. In fact, it shows that the degree of magnetic field stochasticity controls the reconnection. The turbulence in the model is assumed to be sub-Alfvénic, with the magnetic field only slightly perturbed. This ensures that the reconnection happens in generic astrophysical environments and the model does not appeal to any unphysical concepts, similar to the turbulent magnetic diffusivity concept, which is employed in the kinematic magnetic dynamo. The interest to that model has recently increased due to successful numerical testings of the model predictions. In view of this, we discuss implications of the model, including the first-order Fermi acceleration of cosmic rays, that the model naturally entails, bursts of reconnection, that can be associated with Solar flares, as well as, removal of magnetic flux during star-formation.

  12. Redox implications of AMPK-mediated signal transduction beyond energetic clues.

    PubMed

    Cardaci, Simone; Filomeni, Giuseppe; Ciriolo, Maria Rosa

    2012-05-01

    Since the discovery of AMP-dependent protein kinase (AMPK), its fundamental role in regulating metabolic pathways and the molecular mechanism underlying the regulation of its activity by adenine nucleotides has been widely studied. AMPK is not only an energy-responsive enzyme, but it also senses redox signals. This review aims at recapitulating the recent lines of evidence that demonstrate the responsiveness of this kinase to metabolic and nitroxidative imbalance, thus providing new insights into the intimate networks of redox-based signals upstream of AMPK. In particular, we discuss its well-recognized activation downstream of mitochondrial dysfunction, debate the recent findings that AMPK is directly targeted by pro-oxidant species, and question alternative redox pathways that allow AMPK to be included into the large class of redox-sensing proteins. The possible therapeutic implications of the role of AMPK in redox-associated pathologies, such as cancer and neurodegeneration, are also discussed in light of recent advances that suggest a role for AMPK in the tuning of redox-dependent processes, such as apoptosis and autophagy.

  13. Vitamin D Axis in Inflammatory Bowel Diseases: Role, Current Uses and Future Perspectives

    PubMed Central

    Del Pinto, Rita; Ferri, Claudio; Cominelli, Fabio

    2017-01-01

    Increasing evidence supports the concept that the vitamin D axis possesses immunoregulatory functions, with vitamin D receptor (VDR) status representing the major determinant of vitamin D’s pleiotropic effects. Vitamin D promotes the production of anti-microbial peptides, including β-defensins and cathelicidins, the shift towards Th2 immune responses, and regulates autophagy and epithelial barrier integrity. Impairment of vitamin D-mediated pathways are associated with chronic inflammatory conditions, including inflammatory bowel diseases (IBD). Interestingly, inhibition of vitamin D pathways results in dysbiosis of the gut microbiome, which has mechanistically been implicated in the development of IBD. Herein, we explore the role of the vitamin D axis in immune-mediated diseases, with particular emphasis on its interplay with the gut microbiome in the pathogenesis of IBD. The potential clinical implications and therapeutic relevance of this interaction will also be discussed, including optimizing VDR function, both with vitamin D analogues and probiotics, which may represent a complementary approach to current IBD treatments. PMID:29112157

  14. Health Systems Research in a Complex and Rapidly Changing Context: Ethical Implications of Major Health Systems Change at Scale.

    PubMed

    MacGregor, Hayley; Bloom, Gerald

    2016-12-01

    This paper discusses health policy and systems research in complex and rapidly changing contexts. It focuses on ethical issues at stake for researchers working with government policy makers to provide evidence to inform major health systems change at scale, particularly when the dynamic nature of the context and ongoing challenges to the health system can result in unpredictable outcomes. We focus on situations where 'country ownership' of HSR is relatively well established and where there is significant involvement of local researchers and close ties and relationships with policy makers are often present. We frame our discussion around two country case studies with which we are familiar, namely China and South Africa and discuss the implications for conducting 'embedded' research. We suggest that reflexivity is an important concept for health system researchers who need to think carefully about positionality and their normative stance and to use such reflection to ensure that they can negotiate to retain autonomy, whilst also contributing evidence for health system change. A research process informed by the notion of reflexive practice and iterative learning will require a longitudinal review at key points in the research timeline. Such review should include the convening of a deliberative process and should involve a range of stakeholders, including those most likely to be affected by the intended and unintended consequences of change. © 2016 The Authors Developing World Bioethics Published by John Wiley & Sons Ltd.

  15. Ethical Implications: Screening for and Treatment of AIDS.

    ERIC Educational Resources Information Center

    Chng, Chwee Lye; Roddy, William Meyer

    1987-01-01

    This article discusses the ethical implications of using tests intended only to protect the blood supply as diagnostic or prognostic tests for Acquired Immune Deficiency Syndrome (AIDS). The reliability of these tests and the confidentiality of their results are discussed, along with ethical issues of research regarding AIDS. (MT)

  16. Discussions on Aristotle's "Ethics": Implications for Teachers and Administrators.

    ERIC Educational Resources Information Center

    Pemberton, Janette E.

    A number of passages from Aristotle's "Ethics" are discussed in this paper, and their implications for teachers and administrators are examined. Among the many topics considered in relation to teaching and administration are: the importance of performing duties for their own sakes, tbe indispensability of knowledge, the need for…

  17. Corporal Punishment: Legalities, Realities, and Implications.

    ERIC Educational Resources Information Center

    Hinchey, Patricia H.

    2003-01-01

    Presents a quiz that will help readers determine the reliability of their own perceptions relating to corporal punishment in schools. Discusses U.S. Courts and corporal punishment, worldwide and nationwide legality, and the realities of corporal punishment in the United States. Discusses implications for what teachers can do to address corporal…

  18. Integrating normal and abnormal personality structure: a proposal for DSM-V.

    PubMed

    Widiger, Thomas A

    2011-06-01

    The personality disorders section of the American Psychiatric Association's fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) is currently being developed. The purpose of the current paper is to encourage the authors of DSM-V to integrate normal and abnormal personality structure within a common, integrative model, and to suggest that the optimal choice for such an integration would be the five-factor model (FFM) of general personality structure. A proposal for the classification of personality disorder from the perspective of the FFM is provided. Discussed as well are implications and issues associated with an FFM of personality disorder, including validity, coverage, feasibility, clinical utility, and treatment implications.

  19. Some implications for the clinical use of music facilitated imagery.

    PubMed

    Peach, S C

    1984-01-01

    In this study, Helen Bonny's Guided Imagery and Music technique provided the base experience for questionnaire responses from short-term psychiatric inpatients, students, and staff (total/n = 107). Independent measures of age range, sex, medication type, and recent relaxation practice were compared statistically with dependent responses of skin temperature, perceived ability to relax, production of images, and perceived helpfulness of the experience. Results demonstrated increases in skin temperature and relaxation perception and defined the average experience as manifesting three concurrent imagery modes. Among the man independent-dependent variable relationships, some significant differences in mean responses were present. These differences and their possible clinical implications are discussed; further research in the area, including replication, is recommended.

  20. The positive binding energy envelopes of low-mass helium stars

    NASA Astrophysics Data System (ADS)

    Hall, Philip D.; Jeffery, C. Simon

    2018-04-01

    It has been hypothesized that stellar envelopes with positive binding energy may be ejected if the release of recombination energy can be triggered and the calculation of binding energy includes this contribution. The implications of this hypothesis for the evolution of normal hydrogen-rich stars have been investigated, but the implications for helium stars - which may represent mass-transfer or merger remnants in binary star systems - have not. Making a set of model helium stars, we find that those with masses between 0.9 and 2.4 M⊙ evolve to configurations with positive binding energy envelopes. We discuss consequences of the ejection hypothesis for such stars, and possible observational tests of these predictions.

  1. Revisiting the Quantitative-Qualitative Debate: Implications for Mixed-Methods Research

    PubMed Central

    SALE, JOANNA E. M.; LOHFELD, LYNNE H.; BRAZIL, KEVIN

    2015-01-01

    Health care research includes many studies that combine quantitative and qualitative methods. In this paper, we revisit the quantitative-qualitative debate and review the arguments for and against using mixed-methods. In addition, we discuss the implications stemming from our view, that the paradigms upon which the methods are based have a different view of reality and therefore a different view of the phenomenon under study. Because the two paradigms do not study the same phenomena, quantitative and qualitative methods cannot be combined for cross-validation or triangulation purposes. However, they can be combined for complementary purposes. Future standards for mixed-methods research should clearly reflect this recommendation. PMID:26523073

  2. Survey of handwriting instruction practices of elementary teachers and educational programs: implications for occupational therapy.

    PubMed

    Donica, Denise K; Larson, Michelle H; Zinn, Abbey A

    2012-01-01

    ABSTRACT The purpose of this study was to investigate perceptions of elementary school teachers on training in handwriting instruction received during their education, as well as their current classroom practices. The quantity and quality of training in handwriting instruction provided by baccalaureate degree-granting teacher education programs in North Carolina was also examined. An online survey was administered to each population identified to inquire about handwriting instruction practices. Results from 505 teachers and 16 professors indicated that while handwriting instruction content is valued by both teachers and professors, varied levels of training were provided to the teachers. Implications for occupational therapy practice are discussed including strategies for school-based therapists.

  3. Heterogeneous Pathology of Melasma and Its Clinical Implications.

    PubMed

    Kwon, Soon-Hyo; Hwang, Young-Ji; Lee, Soo-Keun; Park, Kyoung-Chan

    2016-05-26

    Melasma is a commonly acquired hypermelanosis that affects sun-exposed areas of the skin, with frequent facial involvement. Its histologic manifestations are evident in the epidermis, extracellular matrix, and dermis. In addition to epidermal pigmentation, pathologic findings of melasma include extracellular matrix abnormality, especially solar elastosis. The disrupted basement membrane has been described in melasma with variable incidences. In the dermis, an increase in vascularity and an increase in the number of mast cells were observed, indicating that dermal factors have critical roles in the pathogenesis of melasma, despite the fact that melasma is characterized by epidermal hyperpigmentation. This review discusses such histologic characteristics of melasma, with consideration to their implications for melasma treatment.

  4. Heterogeneous Pathology of Melasma and Its Clinical Implications

    PubMed Central

    Kwon, Soon-Hyo; Hwang, Young-Ji; Lee, Soo-Keun; Park, Kyoung-Chan

    2016-01-01

    Melasma is a commonly acquired hypermelanosis that affects sun-exposed areas of the skin, with frequent facial involvement. Its histologic manifestations are evident in the epidermis, extracellular matrix, and dermis. In addition to epidermal pigmentation, pathologic findings of melasma include extracellular matrix abnormality, especially solar elastosis. The disrupted basement membrane has been described in melasma with variable incidences. In the dermis, an increase in vascularity and an increase in the number of mast cells were observed, indicating that dermal factors have critical roles in the pathogenesis of melasma, despite the fact that melasma is characterized by epidermal hyperpigmentation. This review discusses such histologic characteristics of melasma, with consideration to their implications for melasma treatment. PMID:27240341

  5. An Exploratory Case Study of a Sexual Assault Telephone Hotline: Training and Practice Implications.

    PubMed

    Colvin, Marianna L; Pruett, Jana A; Young, Stephen M; Holosko, Michael J

    2016-06-29

    Using archival data, this case study systematically examines telephone calls received by a regional sexual assault hotline in the Southeastern United States over a 5-year period. A stratified random sample (n = 383) reveals that hotline staff require diversity and depth in knowledge and skills, demonstrated by the hotline's primary use as a crisis service, combined with notable use by long-term survivors. Findings include the utility of the hotline by survivors and community stakeholders, categories of assault, the time gap between incidents occurring and contacting the hotline, call severity and urgency, and services and referrals provided. Implications for training, practice, and future research are discussed. © The Author(s) 2016.

  6. The evolution of financial incentives in the U.S. health care system.

    PubMed

    Darves-Bornoz, Annie L; Resnick, Matthew J

    2017-01-01

    The U.S. health care system continues to evolve toward value-based payment, rewarding providers based upon outcomes per dollar spent. To date, payment innovation has largely targeted primary care, with little consideration for the role of surgical specialists. As such, there remains appropriate uncertainty surrounding the optimal role of the urologic oncologist in alternative payment models. This commentary summarizes the context of U.S. health care reform and offers insights into supply-side innovations including accountable care organizations and bundled payments. Additionally, and importantly, we discuss the implications of rising out-of-pocket health care expenditures giving rise to health care consumerism and the implications therein. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Authoritative parenting and drug-prevention practices: implications for antidrug ads for parents.

    PubMed

    Stephenson, Michael T; Quick, Brian L; Atkinson, Joshua; Tschida, David A

    2005-01-01

    This research employed the theory of reasoned action to investigate the role of authoritative parenting in 3 drug-prevention behaviors: (a) parental monitoring, (b) parent-child discussions, and (c) awareness of the child's environment. A phone survey of 158 parents of adolescents in 7th, 9th, and 11th grades revealed that authoritative parenting was correlated with parenting practices that reduce the likelihood of adolescent drug use, including discussing family rules about drugs, discussing strategies to avoid drugs, discussing those in trouble with drugs, parental monitoring, knowing the child's plans for the coming day, and personally knowing the child's friends well. Additionally, authoritative parenting moderated the attitude-behavioral intention relation for parental monitoring and awareness of the child's environment, with the weakest relation detected for low-authoritative parents. The utility of these findings in helping design and target antidrug messages for parents more effectively is discussed.

  8. Mindfulness and Fear Extinction: A Brief Review of Its Current Neuropsychological Literature and Possible Implications for Posttraumatic Stress Disorder.

    PubMed

    Kummar, Auretta S

    2017-01-01

    Research in the neuroscience of mindfulness has grown rapidly in recent years. This includes empirical investigations into structural and functional changes in several brain regions-particularly, the hippocampus, the prefrontal cortex, and the amygdala-in association with the practice of mindfulness. Of interest to the current paper is that such brain regions are also implicated in empirical research focusing on fear extinction. While fear extinction has, therefore, been suggested as one of the possible mechanisms to underlie the positive effects of mindfulness, the conceptual links and research implications have lacked specific focus and detailed discussion in the literature. The purpose of this paper is, therefore, two-fold. First, this paper briefly reviews the extant literature on the neuropsychological mechanisms underlying mindfulness-particularly that, which has been found to be similarly implied in fear extinction-and hence, suggests future research directions based on its current state in the literature. Second, this paper explores the implications of this for fear-based psychopathologies, specifically for posttraumatic stress disorder (PTSD). Discussion from this paper suggests the idea of fear extinction as an underlying mechanism of mindfulness to be one that is still preliminary, yet promising; in turn, elucidating the need for further methodologically rigorous study to specifically determine fear extinction as a result of mindfulness, as well as to incorporate neuroimaging techniques in supporting the existing literature that have found preliminary support of mindfulness for PTSD.

  9. Implications of bilateral free trade agreements on access to medicines.

    PubMed Central

    Correa, Carlos María

    2006-01-01

    The TRIPS Agreement of the World Trade Organization (WTO) mandated the introduction of protection of intellectual property rights, notably patents, for pharmaceutical products. While the implications for the access to medicines contained in the terms of this Agreement raised significant concerns, a recent new wave of free trade agreements, negotiated outside the WTO, requires even higher levels of intellectual property protection for medicines than those mandated by that Agreement. The measures involved include the extension of the patent term beyond 20 years; prohibition of use of test data on drug efficacy and safety for certain periods for the approval of generic products; the linkage between drug registration and patent protection; in some cases, limitations to the grounds for granting compulsory licences. This article reviews some of these measures that further limit the competition of generic products and discusses their possible implication for access to medicines. PMID:16710551

  10. A Closer Look at Schlemm's Canal Cell Physiology: Implications for Biomimetics.

    PubMed

    Dautriche, Cula N; Tian, Yangzi; Xie, Yubing; Sharfstein, Susan T

    2015-09-21

    Among ocular pathologies, glaucoma is the second leading cause of progressive vision loss, expected to affect 80 million people worldwide by 2020. A primary cause of glaucoma appears to be damage to the conventional outflow tract. Conventional outflow tissues, a composite of the trabecular meshwork and the Schlemm's canal, regulate and maintain homeostatic responses to intraocular pressure. In glaucoma, filtration of aqueous humor into the Schlemm's canal is hindered, leading to an increase in intraocular pressure and subsequent damage to the optic nerve, with progressive vision loss. The Schlemm's canal encompasses a unique endothelium. Recent advances in culturing and manipulating Schlemm's canal cells have elucidated several aspects of their physiology, including ultrastructure, cell-specific marker expression, and biomechanical properties. This review highlights these advances and discusses implications for engineering a 3D, biomimetic, in vitro model of the Schlemm's canal endothelium to further advance glaucoma research, including drug testing and gene therapy screening.

  11. Is EMDR an effective treatment for people diagnosed with both intellectual disability and post-traumatic stress disorder?

    PubMed

    Gilderthorp, Rosanna C

    2015-03-01

    This study aimed to critically review all studies that have set out to evaluate the use of eye movement desensitization and reprocessing (EMDR) for people diagnosed with both intellectual disability (ID) and post-traumatic stress disorder (PTSD). Searches of the online databases Psych Info, The Cochrane Database of Systematic Reviews, The Cochrane Database of Randomized Control Trials, CINAHL, ASSIA and Medline were conducted. Five studies are described and evaluated. Key positive points include the high clinical salience of the studies and their high external validity. Several common methodological criticisms are highlighted, however, including difficulty in the definition of the terms ID and PTSD, lack of control in design and a lack of consideration of ethical implications. Overall, the articles reviewed indicate cause for cautious optimism about the utility of EMDR with this population. The clinical and research implications of this review are discussed. © The Author(s) 2014.

  12. Implications of genome-wide association studies in cancer therapeutics.

    PubMed

    Patel, Jai N; McLeod, Howard L; Innocenti, Federico

    2013-09-01

    Genome wide association studies (GWAS) provide an agnostic approach to identifying potential genetic variants associated with disease susceptibility, prognosis of survival and/or predictive of drug response. Although these techniques are costly and interpretation of study results is challenging, they do allow for a more unbiased interrogation of the entire genome, resulting in the discovery of novel genes and understanding of novel biological associations. This review will focus on the implications of GWAS in cancer therapy, in particular germ-line mutations, including findings from major GWAS which have identified predictive genetic loci for clinical outcome and/or toxicity. Lessons and challenges in cancer GWAS are also discussed, including the need for functional analysis and replication, as well as future perspectives for biological and clinical utility. Given the large heterogeneity in response to cancer therapeutics, novel methods of identifying mechanisms and biology of variable drug response and ultimately treatment individualization will be indispensable. © 2013 The British Pharmacological Society.

  13. >From individual choice to group decision-making

    NASA Astrophysics Data System (ADS)

    Galam, Serge; Zucker, Jean-Daniel

    2000-12-01

    Some universal features are independent of both the social nature of the individuals making the decision and the nature of the decision itself. On this basis a simple magnet like model is built. Pair interactions are introduced to measure the degree of exchange among individuals while discussing. An external uniform field is included to account for a possible pressure from outside. Individual biases with respect to the issue at stake are also included using local random fields. A unique postulate of minimum conflict is assumed. The model is then solved with emphasis on its psycho-sociological implications. Counter-intuitive results are obtained. At this stage no new physical technicality is involved. Instead the full psycho-sociological implications of the model are drawn. Few cases are then detailed to enlight them. In addition, several numerical experiments based on our model are shown to give both an insight on the dynamics of the model and suggest further research directions.

  14. Epidemiology of infertility: social problems of the infertile couples.

    PubMed

    Araoye, Margaret O

    2003-06-01

    Infertility is of public health importance in Nigeria and many other developing nations because of its high prevalence and especially due to its serious social implications. A review of the epidemiology of infertility in Nigeria and other parts of Sub-Saharan Africa is presented and socio-cultural issues including the social impact on couples are discussed. The major cause of infertility in Africa is infection--STDs, post-abortal and puerperal sepsis. Beliefs about causes, and failure of orthodox methods of treatment have led many couples to seek solution from traditional doctors and faith healers without success. Infertility causes marital disharmony, which often leads to divorce. Women are often blamed for the infertility and men engage in polygyny in an attempt to have children. The couple can also suffer stress from the management of the infertility. Adoption is not popular and assisted reproduction has medico-legal implications. Preventive measures are suggested, including counselling at every stage of the management.

  15. Diabetes and oral disease: implications for health professionals

    PubMed Central

    Albert, David A.; Ward, Angela; Allweiss, Pamela; Graves, Dana T.; Knowler, William C.; Kunzel, Carol; Leibel, Rudolph L.; Novak, Karen F.; Oates, Thomas W.; Papapanou, Panos N.; Schmidt, Ann Marie; Taylor, George W.; Lamster, Ira B.; Lalla, Evanthia

    2012-01-01

    “Diabetes and Oral Disease: Implications for Health Professionals” was a one-day conference convened by the Columbia University College of Dental Medicine, the Columbia University College of Physicians and Surgeons, and the New York Academy of Sciences on May 4, 2011in New York City. The program included an examination of the bidirectional relationship between oral disease and diabetes and the inter-professional working relationships for the care of people who have diabetes. The overall goal of the conference was to promote discussion among the healthcare professions who treat people with diabetes, encourage improved communication and collaboration among them and ultimately, improve patient management of the oral and overall effects of diabetes. Attracting over 150 members of the medical and dental professions from eight different countries, the conference included speakers from academia and government and was divided into four sessions. This report summarizes the scientific presentations of the event. PMID:22409777

  16. Anticancer substances of mushroom origin.

    PubMed

    Ivanova, T S; Krupodorova, T A; Barshteyn, V Y; Artamonova, A B; Shlyakhovenko, V A

    2014-06-01

    The present status of investigations about the anticancer activity which is inherent to medicinal mushrooms, as well as their biomedical potential and future prospects are discussed. Mushroom products and extracts possess promising immunomodulating and anticancer effects, so the main biologically active substances of mushrooms responsible for immunomodulation and direct cytoto-xicity toward cancer cell lines (including rarely mentioned groups of anticancer mushroom proteins), and the mechanisms of their antitumor action were analyzed. The existing to date clinical trials of mushroom substances are mentioned. Mushroom anticancer extracts, obtained by the different solvents, are outlined. Modern approaches of cancer treatment with implication of mushroom products, including DNA vaccinotherapy with mushroom immunomodulatory adjuvants, creation of prodrugs with mushroom lectins that can recognize glycoconjugates on the cancer cell surface, development of nanovectors etc. are discussed. The future prospects of mushroom anticancer substances application, including chemical modification of polysaccharides and terpenoids, gene engineering of proteins, and implementation of vaccines are reviewed.

  17. Fetal growth: a review of terms, concepts and issues relevant to obstetrics.

    PubMed

    Mayer, C; Joseph, K S

    2013-02-01

    The perinatal literature includes several potentially confusing and controversial terms and concepts related to fetal size and growth. This article discusses fetal growth from an obstetric perspective and addresses various issues including the physiologic mechanisms that determine fetal growth trajectories, known risk factors for abnormal fetal growth, diagnostic and prognostic issues related to restricted and excessive growth and temporal trends in fetal growth. Also addressed are distinctions between fetal growth 'standards' and fetal growth 'references', and between fetal growth charts based on estimated fetal weight vs those based on birth weight. Other concepts discussed include the incidence of fetal growth restriction in pregnancy (does the frequency of fetal growth restriction increase or decrease with increasing gestation?), the obstetric implications of studies showing associations between fetal growth and adult chronic illnesses (such as coronary heart disease) and the need for customizing fetal growth standards. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.

  18. The Influence of Climate Change Efficacy Messages and Efficacy Beliefs on Intended Political Participation.

    PubMed

    Hart, P Sol; Feldman, Lauren

    2016-01-01

    Using an online survey experiment with a national sample, this study examined how changing the type and valence of efficacy information in news stories discussing global climate change may impact intended political participation through the mediators of perceived internal, external, and response efficacy. Overall, the results revealed that after a single exposure to a news story, stories including positive internal efficacy content increased perceived internal efficacy, while stories including negative external efficacy content lowered perceived external efficacy. There were limited impacts of other types of efficacy content on perceived efficacy. Perceived internal, external, and response efficacy all offered unique, positive associations with intentions to engage in climate change-related political participation. The results suggest that news stories including positive internal efficacy information in particular have the potential to increase public engagement around climate change. The implications for science communication are discussed.

  19. The Influence of Climate Change Efficacy Messages and Efficacy Beliefs on Intended Political Participation

    PubMed Central

    Hart, P. Sol; Feldman, Lauren

    2016-01-01

    Using an online survey experiment with a national sample, this study examined how changing the type and valence of efficacy information in news stories discussing global climate change may impact intended political participation through the mediators of perceived internal, external, and response efficacy. Overall, the results revealed that after a single exposure to a news story, stories including positive internal efficacy content increased perceived internal efficacy, while stories including negative external efficacy content lowered perceived external efficacy. There were limited impacts of other types of efficacy content on perceived efficacy. Perceived internal, external, and response efficacy all offered unique, positive associations with intentions to engage in climate change-related political participation. The results suggest that news stories including positive internal efficacy information in particular have the potential to increase public engagement around climate change. The implications for science communication are discussed. PMID:27487117

  20. Canine intervertebral disc disease: a review of etiologic and predisposing factors.

    PubMed

    Verheijen, J; Bouw, J

    1982-01-01

    In this report the literature on etiologic and predisposing factors of disc disease in the dog is reviewed and discussed. Hypochondroplasia is considered to be important in the etiology of disc disease. After some consideration on nomenclature and morphology, the genetic background of hypochondroplasia is described. The histochemical morphological and developmental similarities and differences between and within various dog breeds are discussed. Macroscopically visible features that predispose to disc disease are outlined. The biomechanical bow-string model of the vertebral column is reviewed. In the discussion the various literature data are interrelated to show how disc disease might be reduced by breeding measures without implicating the breed characteristics. Literature recommendations to help the individual dog are included.

  1. The Promise and Perils of Population Research on Same-Sex Families.

    PubMed

    Reczek, Corinne; Spiker, Russell; Liu, Hui; Crosnoe, Robert

    2017-12-01

    As a follow-up to our 2016 study, this article presents new findings examining the relationship between same-sex family structure and child health using the 2008-2015 National Health Interview Survey (NHIS). After discussing NIHS data problems, we examine the relationship between family structure and a broad range of child well-being outcomes, including school days lost, behavior, parent-rated health, emotional difficulties, and activity limitations. We find both similarities (school days lost, behavior, parent-rated health) and differences (emotional difficulties and activity limitations) across our two studies using different survey years, but our overall conclusions are robust. We further discuss the implications of our findings for future research on this topic, including how to account for biological relatedness in a study on child health in same-sex families.

  2. Satellite communications for disaster relief operations

    NASA Technical Reports Server (NTRS)

    Sivo, J. N.

    1979-01-01

    The use of existing and planned communication satellite systems to provide assistance in the implementation of disaster relief operations on a global basis was discussed along with satellite communications system implications and their potential impact on field operations in disaster situations. Consideration are given to the utilization of both INTELSAT and MARISAT systems operating at frequencies ranging from 1.5 to 4 GHz and to the size and type of ground terminals necessary for satellite access. Estimates of communication requirements for a global system are given. Some discussion of cost estimates for satellite services to support operations are included. Studies of communication satellites for both pre and post disaster applications conducted for NOAA are included as well as recent experiments conducted in conjunction with the Office of Foreign Disaster Assistance of the Agency for International Development.

  3. Applying a Cognitive Neuroscience Perspective to Disruptive Behavior Disorders: Implications for Schools.

    PubMed

    Tyler, Patrick M; White, Stuart F; Thompson, Ronald W; Blair, R J R

    2018-02-12

    A cognitive neuroscience perspective seeks to understand behavior, in this case disruptive behavior disorders (DBD), in terms of dysfunction in cognitive processes underpinned by neural processes. While this type of approach has clear implications for clinical mental health practice, it also has implications for school-based assessment and intervention with children and adolescents who have disruptive behavior and aggression. This review articulates a cognitive neuroscience account of DBD by discussing the neurocognitive dysfunction related to emotional empathy, threat sensitivity, reinforcement-based decision-making, and response inhibition. The potential implications for current and future classroom-based assessments and interventions for students with these deficits are discussed.

  4. Moving beyond gender: processes that create relationship equality.

    PubMed

    Knudson-Martin, Carmen; Mahoney, Anne Rankin

    2005-04-01

    Equality is related to relationship success, yet few couples achieve it. In this qualitative study, we examine how couples with children in two time cohorts (1982 and 2001) moved toward equality. The analysis identifies three types of couples: Postgender, gender legacy, and traditional. Movement toward equality is facilitated by: (a) Stimulus for change, including awareness of gender, commitment to family and work, and situational pressures; and (b) patterns that promote change, including active negotiation, challenges to gender entitlement, development of new competencies, and mutual attention to relationship and family tasks. Implications for practice are discussed.

  5. Ecology of micro-organisms in a small closed system - Potential benefits and problems for Space Station

    NASA Technical Reports Server (NTRS)

    Rodgers, E. B.; Seale, D. B.; Boraas, M. E.; Sommer, C. V.

    1989-01-01

    The probable sources and implications of microbial contamination on the proposed Space Station are discussed. Because of the limited availability of material, facilities and time on the Space Station, we are exploring the feasibility of replacing traditional incubation methods for assessing microbial contamination with rapid, automated methods. Some possibilities include: ATP measurement, microscopy and telecommunications, and molecular techniques such as DNA probes or monoclonal antibodies. Some of the important ecological factors that could alter microbes in space include microgravity, exposure to radiation, and antibiotic resistance.

  6. Germline genetic variants with implications for disease risk and therapeutic outcomes.

    PubMed

    Pasternak, Amy L; Ward, Kristen M; Luzum, Jasmine A; Ellingrod, Vicki L; Hertz, Daniel L

    2017-10-01

    Genetic testing has multiple clinical applications including disease risk assessment, diagnosis, and pharmacogenomics. Pharmacogenomics can be utilized to predict whether a pharmacologic therapy will be effective or to identify patients at risk for treatment-related toxicity. Although genetic tests are typically ordered for a distinct clinical purpose, the genetic variants that are found may have additional implications for either disease or pharmacology. This review will address multiple examples of germline genetic variants that are informative for both disease and pharmacogenomics. The discussed relationships are diverse. Some of the agents are targeted for the disease-causing genetic variant, while others, although not targeted therapies, have implications for the disease they are used to treat. It is also possible that the disease implications of a genetic variant are unrelated to the pharmacogenomic implications. Some of these examples are considered clinically actionable pharmacogenes, with evidence-based, pharmacologic treatment recommendations, while others are still investigative as areas for additional research. It is important that clinicians are aware of both the disease and pharmacogenomic associations of these germline genetic variants to ensure patients are receiving comprehensive personalized care. Copyright © 2017 the American Physiological Society.

  7. Dealing With the Long-Term Social Implications of Research

    PubMed Central

    Fleischman, Alan; Levine, Carol; Eckenwiler, Lisa; Grady, Christine; Hammerschmidt, Dale E.; Sugarman, Jeremy

    2016-01-01

    Biomedical and behavioral research may affect strongly held social values and thereby create significant controversy over whether such research should be permitted in the first place. Institutional review boards (IRBs) responsible for protecting the rights and welfare of participants in research are sometimes faced with review of protocols that have significant implications for social policy and the potential for negative social consequences. Although IRB members often raise concerns about potential long-term social implications in protocol review, federal regulations strongly discourage IRBs from considering them in their decisions. Yet IRBs often do consider the social implications of research protocols and sometimes create significant delays in initiating or even prevent such research. The social implications of research are important topics for public scrutiny and professional discussion. This article examines the reasons that the federal regulations preclude IRBs from assessing the social risks of research, and examines alternative approaches that have been used with varying success by national advisory groups to provide such guidance. The article concludes with recommendations for characteristics of a national advisory group that could successfully fulfill this need, including sustainability, independence, diverse and relevant expertise, and public transparency. PMID:21534138

  8. Trends in Adult Education with Implications for Vocational Education. Occasional Paper No. 13.

    ERIC Educational Resources Information Center

    Kreitlow, Burton W.

    A discussion is presented of adult education, current trends within the area, and their implications for adult and vocational education programs. The document contains the lecture and a question and answer session. The following sections are presented: (1) overview, defining adult education; (2) major trends, discussing societal pressures for…

  9. Field Dependence/Independence in Second Language Acquisition and Implications for Educators and Instructional Designers.

    ERIC Educational Resources Information Center

    Hoffman, Suzanne Q.

    1997-01-01

    Discusses whether the relationship between field dependence/independence (FD/I) and second-language acquisition is significant. The article contains introductory material defining FD/I within the context of second-language acquisition, a review of relevant research, and a discussion of the research's implications for educators and instructional…

  10. Dependency and Its Implications for Rehabilitation. Northeastern Studies in Vocational Rehabilitation. Monograph No. 1.

    ERIC Educational Resources Information Center

    Goldin, George J.; Perry, Sally L.

    The purpose of this monograph is to summarize professional literature on dependency and to discuss its implications for vocational rehabilitation. The review begins with a discussion of relevant psychoanalytic, learning, developmental, and sociocultural theories since behavioral manifestations of dependency differ and are related to factors in the…

  11. Is Prayer CAM?

    PubMed Central

    Marsman, Kevin; Zwickey, Heather

    2009-01-01

    Abstract Background Alternative medicine researchers and policy makers have classified prayer as a mind–body intervention, and thus, a modality of complementary and alternative medicine (CAM). As such, numerous epidemiological surveys of CAM utilization—which have included prayer—depict increasing CAM use, particularly in specific racial and ethnic groups. Objectives This paper discusses the implications of conflating prayer and CAM, especially regarding the definitions of both concepts and the resulting statistics of CAM utilization. PMID:19388867

  12. FY2017 National Defense Authorization Act: Selected Military Personnel Issues

    DTIC Science & Technology

    2016-07-29

    concerning appropriations, or tax implications of policy choices, topics that are addressed in other CRS products. Issues that have been discussed in...qualified distributions are not included in taxable income, allowing earnings to accrue tax -free. As such, a Roth plan is typically a better savings...vehicle for young, low-income individuals who typically have a lower tax burden (e.g., junior officers and enlisted servicemembers) than they would

  13. Fire resistant aircraft seat materials

    NASA Technical Reports Server (NTRS)

    Trabold, E. L.

    1978-01-01

    The establishment of a technical data base for individual seat materials in order to facilitate materials selections is reviewed. The thermal response of multi-layer constructions representative of the basic functional layers of a typical future seat is examined. These functional layers include: (1) decorative fabric cover; (2) slip sheet (topper); (3) fire blocking layer; (4) cushion reinforcement; and (5) cushioning layer. The implications for material selection for full-scale seats are discussed.

  14. Coping with endometriosis.

    PubMed

    Kaatz, Joyce; Solari-Twadell, P Ann; Cameron, Julie; Schultz, Renee

    2010-01-01

    Endometriosis not only has physical implications for women but also may affect their sexuality, self-image, and hopes for childbearing. This article discusses the role of parish nurses in a community faith-based setting collaborating to provide comprehensive care for women who are diagnosed with endometriosis. Physical, emotional, and spiritual dimensions of care are highlighted. Traditional and complimentary treatments are described. Examples of outcomes for women in the described program are included in case study exemplars.

  15. Light sterile neutrinos and neutrinoless double-beta decay

    NASA Astrophysics Data System (ADS)

    Giunti, Carlo

    2017-10-01

    The LSND, Gallium and reactor neutrino anomalies can be explained by short-baseline neutrino oscillations due to the mixing of the active neutrinos with sterile neutrinos at the eV scale. I review the results of a 3+1 global fit of short-baseline neutrino oscillation data that includes the recent measurements of the MINOS, IceCube, and NEOS experiments, and I discuss the implications for neutrinoless double-beta decay.

  16. Proceedings of the 1983 Annual Meeting of the Canadian Mathematics Education Study Group (7th, Vancouver, British Columbia, June 8-12, 1983).

    ERIC Educational Resources Information Center

    Verhille, Charles, Ed.

    The papers in this document follow the order of the meeting and consist of two guest lecturers and reports from four working groups; two topic group presentations are noted but not included. One lecture, delivered by Peter Hilton, discusses the nature of mathematics today and implications for mathematics teaching, while, in the other paper,…

  17. China-U.S. Relations: Current Issues and Implications for U.S. Policy

    DTIC Science & Technology

    2009-11-20

    would ease restrictions on foreign investments in the culture industry, to include film , publishing, entertainment, online games, and multi-media...President Obama did raise human rights issues in his discussions, in particular the case of American geologist Xue Feng who had been detained several...decision represents a departure from the previous administration of President George W. Bush, which denied import relief in six previous cases of petitions

  18. Outdoor Hazards & Preventive Measures: West Nile Virus: A Clinical Commentary for the Camp Health Care Community; Poison Ivy: A Primer for Prevention; Lyme Disease Prevention and Control.

    ERIC Educational Resources Information Center

    Reynolds, Ellen; Bauer, Holly; Ratner-Connolly, Heidi

    2003-01-01

    Transmitted by mosquitos, West Nile virus may cause serious illness, but the actual likelihood of infection is low. Prevention, implications, and recommendations for camps are discussed. Poison ivy identification, treatment, and complications are presented; a prevention quiz is included. Signs and symptoms of Lyme disease are described, as are…

  19. Corporate coalitions and policy making in the European Union: how and why British American Tobacco promoted "Better Regulation".

    PubMed

    Smith, Katherine Elizabeth; Fooks, Gary; Gilmore, Anna B; Collin, Jeff; Weishaar, Heide

    2015-04-01

    Over the past fifteen years, an interconnected set of regulatory reforms, known as Better Regulation, has been adopted across Europe, marking a significant shift in the way that European Union policies are developed. There has been little exploration of the origins of these reforms, which include mandatory ex ante impact assessment. Drawing on documentary and interview data, this article discusses how and why large corporations, notably British American Tobacco (BAT), worked to influence and promote these reforms. Our analysis highlights (1) how policy entrepreneurs with sufficient resources (such as large corporations) can shape the membership and direction of advocacy coalitions; (2) the extent to which "think tanks" may be prepared to lobby on behalf of commercial clients; and (3) why regulated industries (including tobacco) may favor the use of "evidence tools," such as impact assessments, in policy making. We argue that a key aspect of BAT's ability to shape regulatory reform involved the deliberate construction of a vaguely defined idea that could be strategically adapted to appeal to diverse constituencies. We discuss the theoretical implications of this finding for the Advocacy Coalition Framework, as well as the practical implications of the findings for efforts to promote transparency and public health in the European Union. Copyright © 2015 by Duke University Press.

  20. Corporate coalitions and policymaking in the European Union: How and why British American Tobacco promoted ‘Better Regulation’

    PubMed Central

    Smith, Katherine E.; Fooks, Gary; Gilmore, Anna B.; Collin, Jeff; Weishaar, Heide

    2015-01-01

    Over the past fifteen years, an inter-connected set of regulatory reforms, known as Better Regulation, has been adopted across Europe, marking a significant shift in the way European Union (EU) policies are developed. There has been little exploration of the origins of these reforms, which include mandatory ex-ante impact assessment. Drawing on documentary and interview data, this paper discusses how and why large corporations, notably British American Tobacco (BAT), worked to influence and promote these reforms. Our analysis highlights: (i) how policy entrepreneurs with sufficient resources (such as large corporations) can shape the membership and direction of advocacy coalitions; (ii) the extent to which ‘think tanks’ may be prepared to lobby on behalf of commercial clients; and (iii) why regulated industries (including tobacco) may favour the use of ‘evidence-tools’, such as impact assessments, in policymaking. We argue a key aspect of BAT’s ability to shape regulatory reform involved the deliberate construction of a vaguely defined idea that could be strategically adapted to appeal to diverse constituencies. We discuss the theoretical implications of this finding for the ‘Advocacy Coalition Framework’, as well as the practical implications of the findings for efforts to promote ‘transparency’ and public health in the EU. PMID:25646389

  1. Risky individuals and the politics of genetic research into aggressiveness and violence.

    PubMed

    Pieri, Elisa; Levitt, Mairi

    2008-11-01

    New genetic technologies promise to generate valuable insights into the aetiology of several psychiatric conditions, as well as a wider range of human and animal behaviours. Advances in the neurosciences and the application of new brain imaging techniques offer a way of integrating DNA analysis with studies that are looking at other biological markers of behaviour. While candidate 'genes for' certain conditions, including schizophrenia and bipolar disorders, are said to be 'un-discovered' at a faster rate than they are discovered, many studies are being conducted on personality traits such as aggressiveness and anti-social traits. The clinical applicability and implications of these studies are often discussed within the scientific community. However, little attention has so far been paid to their possible policy implications in relation to criminality management and to Criminal Law itself. Similarly, the related ethical issues arising in the field of crime control, and the tensions between enhancing security for society and protecting civil liberties, are currently under-explored. This paper investigates these ethical issues by focusing on the views of those professionals - including judges, lawyers, probation officers and social workers - who work with individuals 'deemed at risk' of violent and aggressive behaviours. It also discusses and problematizes mainstream rhetoric and arguments around the notion of 'risky individuals'.

  2. Temperament, Emotion and Childhood Stuttering

    PubMed Central

    Jones, Robin; Choi, Dahye; Conture, Edward; Walden, Tedra

    2015-01-01

    The purpose of this article is to provide a brief description of temperament and emotion, review empirical evidence pertaining to their possible association with childhood stuttering, and discuss possible clinical implications. In general, temperament is typically thought of as an individual's constitutionally (biologically) based behavioral proclivities. These proclivities often include emotional reactivity and self-regulation. Reactivity refers to arousal of emotions, motor activity, and attention, and self-regulation refers to the ability to moderate those tendencies. The trait-like nature of temperament makes it potentially salient to our understanding of the onset and development of stuttering because temperamental tendencies may result in greater reactivity or difficulty in coping. Emotions, which are more state-like and variable, may influence the variation of stuttering commonly observed both within and between speaking situations. Temperament and emotion may serve as a causal contributor to developmental stuttering, with empirical findings indicating that preschool-aged children who stutter (CWS) exhibit differences in temperament and emotion when compared with children who do not stutter (CWNS). Given that empirical study of temperament in preschool-aged CWS is nascent, extensive discussion of clinical implications is challenging. With that caution, we present some early possibilities, including matching treatment approaches with the child's temperamental profile and using temperament as a predictor of treatment outcome. PMID:24782274

  3. Practitioner Review: Multilingualism and neurodevelopmental disorders - an overview of recent research and discussion of clinical implications.

    PubMed

    Uljarević, Mirko; Katsos, Napoleon; Hudry, Kristelle; Gibson, Jenny L

    2016-11-01

    Language and communication skills are essential aspects of child development, which are often disrupted in children with neurodevelopmental disorders. Cutting edge research in psycholinguistics suggests that multilingualism has potential to influence social, linguistic and cognitive development. Thus, multilingualism has implications for clinical assessment, diagnostic formulation, intervention and support offered to families. We present a systematic review and synthesis of the effects of multilingualism for children with neurodevelopmental disorders and discuss clinical implications. We conducted systematic searches for studies on multilingualism in neurodevelopmental disorders. Keywords for neurodevelopmental disorders were based on Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition categories as follows; Intellectual Disabilities, Communication Disorders, Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder, Specific Learning Disorder, Motor Disorders, Other Neurodevelopmental Disorders. We included only studies based on empirical research and published in peer-reviewed journals. Fifty studies met inclusion criteria. Thirty-eight studies explored multilingualism in Communication Disorders, 10 in ASD and two in Intellectual Disability. No studies on multilingualism in Specific Learning Disorder or Motor Disorders were identified. Studies which found a disadvantage for multilingual children with neurodevelopmental disorders were rare, and there appears little reason to assume that multilingualism has negative effects on various aspects of functioning across a range of conditions. In fact, when considering only those studies which have compared a multilingual group with developmental disorders to a monolingual group with similar disorders, the findings consistently show no adverse effects on language development or other aspects of functioning. In the case of ASD, a positive effect on communication and social functioning has been observed. There is little evidence to support the widely held view that multilingual exposure is detrimental to the linguistic or social development of individuals with neurodevelopmental disorders. However, we also note that the available pool of studies is small and the number of methodologically high quality studies is relatively low. We discuss implications of multilingualism for clinical management of neurodevelopmental disorders, and discuss possible directions for future research. © 2016 Association for Child and Adolescent Mental Health.

  4. Exploring morally relevant issues facing families in their decisions to monitor the health-related behaviours of loved ones.

    PubMed

    Gammon, D; Christiansen, E K; Wynn, R

    2009-07-01

    Patient self-management of disease is increasingly supported by technologies that can monitor a wide range of behavioural and biomedical parameters. Incorporated into everyday devices such as cell phones and clothes, these technologies become integral to the psychosocial aspects of everyday life. Many technologies are likely to be marketed directly to families with ill members, and families may enlist the support of clinicians in shaping use. Current ethical frameworks are mainly conceptualised from the perspective of caregivers, researchers, developers and regulators in order to ensure the ethics of their own practices. This paper focuses on families as autonomous decision-makers outside the regulated context of healthcare. We discuss some morally relevant issues facing families in their decisions to monitor the health-related behaviours of loved ones. An example - remote parental monitoring of adolescent blood glucose - is presented and discussed through the lens of two contrasting accounts of ethics; one reflecting the predominant focus on health outcomes within the health technology assessment (HTA) framework and the other that attends to the broader sociocultural contexts shaping technologies and their implications. Issues discussed include the focus of assessments, informed consent and child assent, and family co-creation of system characteristics and implications. The parents' decisions to remotely monitor their child has relational implications that are likely to influence conflict levels and thus also health outcomes. Current efforts to better integrate outcome assessments with social and ethical assessments are particularly relevant for informed decision-making about health monitoring technologies in families.

  5. Procreative liberty, embryos, and collaborative reproduction: a legal perspective.

    PubMed

    Robertson, J A

    1987-01-01

    This article discusses the implications of a constitutionally protected right to procreate using a wide range of reproductive choices made possible by noncoital reproductive technologies, including embryo freezing and donation and surrogate gestation. After establishing the constitutional basis for a positive right to procreate, it discusses the extent to which concerns about the welfare of embryos, offspring, donors, and surrogates justifies limitation on reproductive choice involving these technologies. While tangible harm to offspring and protection of the free choice of reproductive collaborators may justify regulation, moral condemnation of noncoital techniques and concerns about the reifying effects of their use are an insufficient basis for state restriction.

  6. Beyond "Landscapes of Despair": the need for new research on the urban environment, sprawl, and the community integration of persons with severe mental illness.

    PubMed

    Yanos, Philip T

    2007-09-01

    The purpose of this commentary is to discuss important trends in the housing of people with severe mental illness in the past 20 years that require the attention of mental health geographers and other experts on the effects of place on mental health. Issues that are worthy of consideration in new research include: assessing the impact of place effects on community integration, the impact of sprawl, and the emergence of the independent scatter-site housing model. Possible implications of these trends for the effects of place on people with severe mental illness are discussed.

  7. General flat four-dimensional world pictures and clock systems

    NASA Technical Reports Server (NTRS)

    Hsu, J. P.; Underwood, J. A.

    1978-01-01

    We explore the mathematical structure and the physical implications of a general four-dimensional symmetry framework which is consistent with the Poincare-Einstein principle of relativity for physical laws and with experiments. In particular, we discuss a four-dimensional framework in which all observers in different frames use one and the same grid of clocks. The general framework includes special relativity and a recently proposed new four-dimensional symmetry with a nonuniversal light speed as two special simple cases. The connection between the properties of light propagation and the convention concerning clock systems is also discussed, and is seen to be nonunique within the four-dimensional framework.

  8. Optimizing Oxygenation in the Mechanically Ventilated Patient: Nursing Practice Implications.

    PubMed

    Barton, Glenn; Vanderspank-Wright, Brandi; Shea, Jacqueline

    2016-12-01

    Critical care nurses constitute front-line care provision for patients in the intensive care unit (ICU). Hypoxemic respiratory compromise/failure is a primary reason that patients require ICU admission and mechanical ventilation. Critical care nurses must possess advanced knowledge, skill, and judgment when caring for these patients to ensure that interventions aimed at optimizing oxygenation are both effective and safe. This article discusses fundamental aspects of respiratory physiology and clinical indices used to describe oxygenation status. Key nursing interventions including patient assessment, positioning, pharmacology, and managing hemodynamic parameters are discussed, emphasizing their effects toward mitigating ventilation-perfusion mismatch and optimizing oxygenation. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Robosphere: Self Sustaining Robotic Ecologies as Precursors to Human Planetary Exploration

    NASA Technical Reports Server (NTRS)

    Colombano, Silvano P.

    2003-01-01

    The present sequential mission oriented approach to robotic planetary exploration, could be changed to an infrastructure building approach where a robotic presence is permanent, self sustaining and growing with each mission. We call this self-sustaining robotic ecology approach robosphere and discuss the technological issues that need to be addressed before this concept can be realized. One of the major advantages of this approach is that a robosphere would include much of the infrastructure required by human explorers and would thus lower the preparation and risk threshold inherent in the transition from robotic to human exploration. In this context we discuss some implications for space architecture.

  10. Insurance and indemnification implications of future space projects

    NASA Technical Reports Server (NTRS)

    O'Brien, John E.

    1987-01-01

    NASA options regarding insurance and indemnification policies as they relate to NASA customers and contractors are described. The foundation for the discussion is the way in which NASA is planning to return the Space Shuttle fleet to safe flight as well as current U.S. policy concerning future uses of the Shuttle fleet. Issues discussed include: the nature of the Shuttle manifest; the policy regarding property damage or destruction; insurance against liability to third parties; the reduction of the scope of the risk to be insured; NASA as the insurer; a sharing arrangement between the user and NASA; and contractors and subcontractors involved in Shuttle operations.

  11. Testosterone and cardiovascular disease in men

    PubMed Central

    Morris, Paul D; Channer, Kevin S

    2012-01-01

    Despite regional variations in the prevalence of coronary artery disease (CAD), men are consistently more at risk of developing and dying from CAD than women, and the gender-specific effects of sex hormones are implicated in this inequality. This ‘Perspectives' article reviews the current evidence regarding the cardiovascular effects of testosterone in men including an examination of the age-related decline in testosterone, the relationship between testosterone levels and coronary disease, coronary risk factors and mortality. We also review the vaso-active effects of testosterone, and discuss how these have been used in men with heart failure and angina. We discuss the ‘cause' versus ‘effect' controversy, regarding low testosterone levels in men with coronary heart disease, as well as concerns over the use of testosterone replacement therapy in middle aged and elderly men. The article concludes with a discussion regarding the future direction for work in this interesting area, including the relative merits of screening for, and treating hypogonadism with testosterone replacement therapy in men with heart disease. PMID:22522504

  12. Implications of Stellar Feedback for Dynamical Modeling of the Milky Way and Dwarf Galaxies

    NASA Astrophysics Data System (ADS)

    Wetzel, Andrew

    2018-04-01

    I will present recent results on dynamical modeling of stellar populations from the FIRE cosmological zoom-in baryonic simulations of Milky Way-like and dwarf galaxies. First, I will discuss the dynamical formation of the Milky Way, including the origin of thin+thick stellar disk morphology. I also will discuss the curious origin of metal-rich stars on halo-like orbits near the Sun, as recently measured by Gaia, with new insights from FIRE simulations on stellar radial migration/heating. Next, I will discuss role of stellar feedback in generating non-equilibrium fluctuations of the gravitational potential in low-mass 'dwarf' galaxies, which can explain the origin of cores in their dark-matter density profiles. In particular, we predict significant observable effects on stellar dynamics, including radial migration, size fluctuations, and population gradients, which can provide observational tests of feedback-driven core formation. Finally, this scenario can explain the formation of newly discovered 'ultra-diffuse' galaxies.

  13. Buprenorphine and Buprenorphine/Naloxone Diversion, Misuse, and Illicit Use: An International Review

    PubMed Central

    Yokell, Michael A.; Zaller, Nickolas D.; Green, Traci C.; Rich, Josiah D.

    2011-01-01

    The diversion, misuse, and non-medically supervised use of buprenorphine and buprenorphine/naloxone by opioid users are reviewed. Buprenorphine and buprenorphine/naloxone are used globally as opioid analgesics and in the treatment of opioid dependency. Diversion of buprenorphine and buprenorphine/naloxone represents a complex medical and social issue, and has been widely documented in various geographical regions throughout the world. We first discuss the clinical properties of buprenorphine and its abuse potential. Second, we discuss its diversion and illicit use on an international level, as well as motivations for those activities. Third, we examine the medical risks and benefits of buprenorphine’s non-medically supervised use and misuse. These risks and benefits include the effect of buprenorphine’s use on HIV risk and the risk of its concomitant use with other medications and drugs of abuse. Finally, we discuss the implications of diversion, misuse, and non-medically supervised use (including potential measures to address issues of diversion); and potential areas for further research. PMID:21466501

  14. The epistemically virtuous clinician.

    PubMed

    Marcum, James A

    2009-01-01

    Today, modern Western medicine is facing a quality-of-care crisis that is undermining the patient-physician relationship. In this paper, a notion of the epistemically virtuous clinician is proposed in terms of both the reliabilist and responsibilist versions of virtue epistemology, in order to help address this crisis. To that end, a clinical case study from the literature is first reconstructed. The reliabilist intellectual virtues, including the perceptual and conceptual virtues, are then discussed and applied to the case study. Next, a similar method is employed to examine the responsibilist intellectual virtues, including curiosity, courage, honesty, and humility, and to apply them to the case study. To round out the discussion, the love of knowledge and both theoretical and practical wisdom are explored and applied to the case study. The paper concludes with a brief discussion of how the notion of an epistemically virtuous clinician addresses the quality-of-care crisis, in terms of the connection between ethical and intellectual virtues, and of the notion's implications for medical education.

  15. Ice Nucleation in the Tropical Tropopause Layer: Implications for Cirrus Occurrence, Cirrus Microphysical Properties, and Dehydration of Air Entering the Stratosphere

    NASA Technical Reports Server (NTRS)

    Jensen, Eric; Kaercher, Bernd; Ueyama, Rei; Pfister, Leonhard

    2017-01-01

    Recent laboratory experiments have advanced our understanding of the physical properties and ice nucleating abilities of aerosol particles atlow temperatures. In particular, aerosols containing organics will transition to a glassy state at low temperatures, and these glassy aerosols are moderately effective as ice nuclei. These results have implications for ice nucleation in the cold Tropical Tropopause Layer (TTL; 13-19 km). We have developed a detailed cloud microphysical model that includes heterogeneous nucleation on a variety of aerosol types and homogeneous freezing of aqueous aerosols. This model has been incorporated into one-dimensional simulations of cirrus and water vapor driven by meteorological analysis temperature and wind fields. The model includes scavenging of ice nuclei by sedimenting ice crystals. The model is evaluated by comparing the simulated cloud properties and water vapor concentrations with aircraft and satellite measurements. In this presentation, I will discuss the relative importance of homogeneous and heterogeneous ice nucleation, the impact of ice nuclei scavenging as air slowly ascends through the TTL, and the implications for the final dehydration of air parcels crossing the tropical cold-point tropopause and entering the tropical stratosphere.

  16. Summer learning and its implications: insights from the Beginning School Study.

    PubMed

    Alexander, Karl L; Entwisle, Doris R; Olson, Linda Steffel

    2007-01-01

    There is perhaps no more pressing issue in school policy today than the achievement gap across social lines. Achievement differences between well-to-do children and poor children and between disadvantaged racial and ethnic minorities and majority whites are large when children first begin school, and they increase over time. Despite years of study and an abundance of good intentions, these patterned achievement differences persist, but who is responsible, and how are schools implicated? The increasing gap seems to suggest that schools are unable to equalize educational opportunity or, worse still, that they actively handicap disadvantaged children. But a seasonal perspective on learning yields a rather different impression. Comparing achievement gains separately over the school year and the summer months reveals that much of the achievement gap originates over the summer period, when children are not in school. The authors review Beginning School Study research on differential summer learning across social lines (that is, by family socioeconomic level) and its implications for later schooling outcomes, including high school curriculum placements, high school dropout, and college attendance. These studies document the extent to which these large summer learning differences impede the later educational progress of children of low socioeconomic status. Practical implications are discussed, including the need for early and sustained interventions to prevent the achievement gap from opening wide in the first place and for high-quality summer programming focused on preventing differential summer learning loss.

  17. Biological Consequences and Health Risks Of Low-Level Exposure to Ionizing Radiation: Commentary on the Workshop

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Feinendegen, Ludwig E.; Brooks, Antone L.; Morgan, William F.

    2011-03-01

    This paper provides an integration and discussion of the information presented at the workshop held from May 2 to 5, 2010, in Richland, WA, adjacent to the Pacific Northwest National Laboratory (PNNL). Consequently, this is commentary and not necessarily a consensus document. This workshop was in honor of Dr. Victor P. Bond in celebration of his numerous contributions to the radiation sciences. Internationally recognized experts in biophysics, experimental radiation biology, epidemiology, and risk assessment were invited to discuss all issues of low-dose risk. This included the physics of track structure and its consequences to dosimetry, primary and secondary responses atmore » the molecular, cellular, and tissue biology levels, epidemiology, definitions of risk, and the practical and regulatory applications of these issues including their biomedical and social consequences. Of major concern was the present state of knowledge about cancer risk and other risks in humans following intentional or accidental exposures to low doses and low dose-rates of ionizing radiation (below about 100 mSv accumulated dose). This includes low dose exposures which occur during radiation therapy in tissues located outside of the irradiated volume. The interdisciplinary approach of this workshop featured discussions rather than formal presentations in ten separate consecutive sessions. Each session was led by chairpersons, listed in the opening of the workshop, which introduced topics, facts and posed relevant questions. The content of each session is given by a brief summary followed by the abstracts from the primary discussants in the session as has been presented in the previous section. This manuscript provides additional review and discussion of the sessions and tracks the topics and issues discussed as follows: • Energy deposition through particle tracks in tissues. • Energy deposition and primary effects in tissues. • Consequences of experimental advances in radiobiology • Non-targeted radiation effects. • System biological considerations. • Propagation of perturbations in the system. • Immediately operating protections. • Delayed stress response protections • Low-dose induced adaptive protections. • Integrated defenses against cancer. • Endogenous versus radiogenic cancer. • The epidemiological dilemma. • Dose-risk functions for different exposure modalities. • Implications for research. • Implications for regulation and protection. A brief summary of the discussions and results on each of these topics and issues is presented in this paper. Additional details of these discussions are provided in the workshop session summaries grouped into topics and followed by applicable abstracts/synopses submitted by the workshop participants.« less

  18. Characterization of 3D interconnected microstructural network in mixed ionic and electronic conducting ceramic composites

    NASA Astrophysics Data System (ADS)

    Harris, William M.; Brinkman, Kyle S.; Lin, Ye; Su, Dong; Cocco, Alex P.; Nakajo, Arata; Degostin, Matthew B.; Chen-Wiegart, Yu-Chen Karen; Wang, Jun; Chen, Fanglin; Chu, Yong S.; Chiu, Wilson K. S.

    2014-04-01

    The microstructure and connectivity of the ionic and electronic conductive phases in composite ceramic membranes are directly related to device performance. Transmission electron microscopy (TEM) including chemical mapping combined with X-ray nanotomography (XNT) have been used to characterize the composition and 3-D microstructure of a MIEC composite model system consisting of a Ce0.8Gd0.2O2 (GDC) oxygen ion conductive phase and a CoFe2O4 (CFO) electronic conductive phase. The microstructural data is discussed, including the composition and distribution of an emergent phase which takes the form of isolated and distinct regions. Performance implications are considered with regards to the design of new material systems which evolve under non-equilibrium operating conditions.The microstructure and connectivity of the ionic and electronic conductive phases in composite ceramic membranes are directly related to device performance. Transmission electron microscopy (TEM) including chemical mapping combined with X-ray nanotomography (XNT) have been used to characterize the composition and 3-D microstructure of a MIEC composite model system consisting of a Ce0.8Gd0.2O2 (GDC) oxygen ion conductive phase and a CoFe2O4 (CFO) electronic conductive phase. The microstructural data is discussed, including the composition and distribution of an emergent phase which takes the form of isolated and distinct regions. Performance implications are considered with regards to the design of new material systems which evolve under non-equilibrium operating conditions. Electronic supplementary information (ESI) available. See DOI: 10.1039/c3nr06684c

  19. Implications of complex adaptive systems theory for the design of research on health care organizations

    PubMed Central

    McDaniel, Reuben R.; Lanham, Holly Jordan; Anderson, Ruth A.

    2013-01-01

    Background Because health care organizations (HCOs) are complex adaptive systems (CASs), phenomena of interest often are dynamic and unfold in unpredictable ways, and unfolding events are often unique. Researchers of HCOs may recognize that the subject of their research is dynamic; however, their research designs may not take this into account. Researchers may also know that unfolding events are often unique, but their design may not have the capacity to obtain information from meager evidence. Purpose These two concerns led us to examine two ideas from organizational theory: (a) the ideas of K. E. Weick (1993) on organizational design as a verb and (b) the ideas of J. G. March, L. S. Sproull, and M. Tamuz (1991) on learning from samples of one or fewer. In this article, we applied these ideas to develop an enriched perspective of research design for studying CASs. Methodology/Approach We conducted a theoretical analysis of organizations as CASs, identifying relevant characteristics for research designs. We then explored two ideas from organizational theory and discussed the implications for research designs. Findings Weick's idea of “design as a verb” helps in understanding dynamic and process-oriented research design. The idea of “learning from samples of one or fewer” of March, Sproull, and Tamuz provides strategies for research design that enables learning from meager evidence. When studying HCOs, research designs are likely to be more effective when they (a) anticipate change, (b) include tension, (c) capitalize on serendipity, and (d) use an “act-then-look” mind set. Implications for practice are discussed. Practice Implications Practitioners who understand HCOs as CASs will be cautious in accepting findings from studies that treat HCOs mechanistically. They will consider the characteristics of CAS when evaluating the evidence base for practice. Practitioners can use the strategies proposed in this article to stimulate discussion with researchers seeking to conduct research in their HCO. PMID:19322050

  20. Manned Mars mission radiation environment and radiobiology

    NASA Technical Reports Server (NTRS)

    Nachtwey, D. S.

    1986-01-01

    Potential radiation hazards to crew members on manned Mars missions are discussed. It deals briefly with radiation sources and environments likely to be encountered during various phases of such missions, providing quantitative estimates of these environments. Also provided are quantitative data and discussions on the implications of such radiation on the human body. Various sorts of protective measures are suggested. Recent re-evaluation of allowable dose limits by the National Council of Radiation Protection is discussed, and potential implications from such activity are assessed.

  1. Nanotechnology Applications and Implications of Agrochemicals toward Sustainable Agriculture and Food Systems.

    PubMed

    Scott, Norman R; Chen, Hongda; Cui, Haixin

    2018-06-08

    The first international conference on Nanotechnology Applications and Implications of Agrochemicals toward Sustainable Agriculture and Food Systems was held in Beijing, China on November 17-18, 2016 to address and exchange latest knowledge and developments in nanotechnology of agrochemicals toward sustainable agriculture and food systems. World-leading scientists gathered to discuss a wide range of relevant topics. The purposes of this paper are to provide: an introduction to the international conference, summarize in brief the contributions of papers that follow within this special issue of Journal of Agricultural and Food Chemistry, provide a synthesis of conference outcomes, suggest future directions including an important role of converging science and technologies to advance sustainable agriculture, food, and natural resource systems.

  2. Lysosomal membrane permeabilization in cell death: new evidence and implications for health and disease.

    PubMed

    Serrano-Puebla, Ana; Boya, Patricia

    2016-05-01

    Recent studies have demonstrated that, in addition to their central role in cellular catabolic reactions, lysosomes are implicated in many cellular processes, including metabolism, membrane repair, and cell death. Lysosomal membrane permeabilization (LMP) has emerged as a pathway by which cell demise is regulated under physiological conditions and contributes to cell death in many pathological situations. Here, we review the latest evidence on LMP-mediated cell death, the upstream and downstream signals involved, and the role of LMP in the normal physiology of organisms. We also discuss the contributions of lysosomal damage and LMP to the pathogenic features of several disease states, such as lysosomal storage disorders and other neurodegenerative conditions. © 2015 New York Academy of Sciences.

  3. AMPK-mediated regulation of neuronal metabolism and function in brain diseases.

    PubMed

    Liu, Yu-Ju; Chern, Yijuang

    2015-01-01

    The AMP-activated protein kinase (AMPK) is a serine/threonine kinase that functions as a key energy sensor in a wide variety of tissues. This kinase has been a major drug target for metabolic diseases (e.g., type 2 diabetes) and cancers. For example, metformin (an activator of AMPK) is a first-line diabetes drug that protects against cancers. Abnormal regulation of AMPK has been implicated in several brain diseases, including Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and stroke. Given the emerging importance of neurodegenerative diseases in our aging societies, this review features the recent studies that have delineated the functions of AMPK in brain diseases and discusses their potential clinical implications or roles as drug targets in brain diseases.

  4. Regulated necrosis and its implications in toxicology.

    PubMed

    Aki, Toshihiko; Funakoshi, Takeshi; Uemura, Koichi

    2015-07-03

    Recent research developments have revealed that caspase-dependent apoptosis is not the sole form of regulated cell death. Caspase-independent, but genetically regulated, forms of cell death include pyroptosis, necroptosis, parthanatos, and the recently discovered ferroptosis and autosis. Importantly, regulated necrosis can be modulated by small molecule inhibitors/activators, confirming the cell autonomous mechanism of these forms of cell death. The success of small molecule-mediated manipulation of regulated necrosis has produced great changes in the field of cell death research, and has also brought about significant changes in the fields of pharmacology as well as toxicology. In this review, we intend to summarize the modes of regulated cell death other than apoptosis, and discuss their implications in toxicology. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  5. Clinical implications of basic science discoveries: janus resurrected--two faces of B cell and plasma cell biology.

    PubMed

    Woodle, E S; Rothstein, D M

    2015-01-01

    B cells play a complex role in the immune response. In addition to giving rise to plasma cells (PCs) and promoting T cell responses via antigen presentation, they perform immunoregulatory functions. This knowledge has created concerns regarding nonspecific B cell depletional therapy because of the potential to paradoxically augment immune responses. Recent studies now indicate that PCs have immune functions beyond immunoglobulin synthesis. Evidence for a new role for PCs as potent regulatory cells (via IL-10 and IL-35 production) is discussed including the implications for PC-targeted therapies currently being developed for clinical transplantation. © Copyright 2014 The American Society of Transplantation and the American Society of Transplant Surgeons.

  6. Radiative transfer in real atmospheres. [the implications for recognition processing of multispectral remote sensing data

    NASA Technical Reports Server (NTRS)

    Turner, R. E.

    1974-01-01

    The problem of multiple radiation scattering in an atmosphere characterized by various amounts of aerosol absorption and different particle size distributions was investigated. The visible part of the spectrum was emphasized, including the effect of ozone absorption. An atmosphere bounded by a nonhomogenous, Lambertian surface was also studied, along with the effect of background radiation on target in terms of various atmopheric and geometric conditions. Results of the investigation indicate that comtaminated atmospheres can change the radiation field by a considerable amount, and that the effect of non-uniform surface significantly alters the intrinsic radiation from a target element. The implications of these results for the recognition processing of multispectral remote sensing data is discussed.

  7. From what should we protect future generations: germ-line therapy or genetic screening?

    PubMed

    Mallia, Pierre; ten Have, Henk

    2003-01-01

    This paper discusses the issue of whether we have responsibilities to future generations with respect to genetic screening, including for purposes of selective abortion or discard. Future generations have been discussed at length among scholars. The concept of 'Guardian for Future Generations' is tackled and its main criticisms discussed. Whilst germ-line cures, it is argued, can only affect family trees, genetic screening and testing can have wider implications. If asking how this may affect future generations is a legitimate question and since we indeed make retrospective moral judgements, it would be wise to consider that future generations will make the same retrospective judgements on us. Moreover such technologies affect present embryos to which we indeed can be considered to have an obligation.

  8. Future methods in pharmacy practice research.

    PubMed

    Almarsdottir, A B; Babar, Z U D

    2016-06-01

    This article describes the current and future practice of pharmacy scenario underpinning and guiding this research and then suggests future directions and strategies for such research. First, it sets the scene by discussing the key drivers which could influence the change in pharmacy practice research. These are demographics, technology and professional standards. Second, deriving from this, it seeks to predict and forecast the future shifts in use of methodologies. Third, new research areas and availability of data impacting on future methods are discussed. These include the impact of aging information technology users on healthcare, understanding and responding to cultural and social disparities, implementing multidisciplinary initiatives to improve health care, medicines optimization and predictive risk analysis, and pharmacy as business and health care institution. Finally, implications of the trends for pharmacy practice research methods are discussed.

  9. Ethical, legal, and social implications of incorporating genomic information into electronic health records.

    PubMed

    Hazin, Ribhi; Brothers, Kyle B; Malin, Bradley A; Koenig, Barbara A; Sanderson, Saskia C; Rothstein, Mark A; Williams, Marc S; Clayton, Ellen W; Kullo, Iftikhar J

    2013-10-01

    The inclusion of genomic data in the electronic health record raises important ethical, legal, and social issues. In this article, we highlight these challenges and discuss potential solutions. We provide a brief background on the current state of electronic health records in the context of genomic medicine, discuss the importance of equitable access to genome-enabled electronic health records, and consider the potential use of electronic health records for improving genomic literacy in patients and providers. We highlight the importance of privacy, access, and security, and of determining which genomic information is included in the electronic health record. Finally, we discuss the challenges of reporting incidental findings, storing and reinterpreting genomic data, and nondocumentation and duty to warn family members at potential genetic risk.

  10. The history of nurse imagery and the implications for recruitment: a discussion paper.

    PubMed

    Price, Sheri L; McGillis Hall, Linda

    2014-07-01

    This paper presents a discussion of the history of nurse imagery in the context of recent career choice research and the need for contemporary images for nursing recruitment. The critical and growing shortage of nurses is a global concern. Understanding how individuals come to know nursing as a career choice is of critical importance. Stereotypical imaging and messaging of the nursing profession have been shown to shape nurses' expectations and perceptions of nursing as a career, which has implications for both recruitment and retention. Relevant research and literature on nurse imagery in relation to career choice and recruitment were identified through a search of the CINAHL, PsychINFO, Sociological Abstracts, PubMed; Medline and Embase databases from 1970-2012. Historical images of nurses and nursing remain prevalent in society today and continue to influence the choice of nursing as a career among the upcoming generation of nurses. Students interested in nursing may be dissuaded from choosing it as a career based on negative, stereotypical images, especially those that position the profession as inferior to medicine. Understanding the evolution and perpetuation of popular images and messages in relation to the profession has implications for not only how we recruit and retain future generations of professional nurses but also holds implications for interprofessional collaboration between nursing and other health disciplines. Strategies for future recruitment and socialization within the nursing and the health professions need to include contemporary and realistic imaging of both health professional roles and practice settings. © 2013 John Wiley & Sons Ltd.

  11. Polarizing news? Representations of threat and efficacy in leading US newspapers' coverage of climate change.

    PubMed

    Feldman, Lauren; Hart, P Sol; Milosevic, Tijana

    2017-05-01

    This study examines non-editorial news coverage in leading US newspapers as a source of ideological differences on climate change. A quantitative content analysis compared how the threat of climate change and efficacy for actions to address it were represented in climate change coverage across The New York Times, The Wall Street Journal, The Washington Post, and USA Today between 2006 and 2011. Results show that The Wall Street Journal was least likely to discuss the impacts of and threat posed by climate change and most likely to include negative efficacy information and use conflict and negative economic framing when discussing actions to address climate change. The inclusion of positive efficacy information was similar across newspapers. Also, across all newspapers, climate impacts and actions to address climate change were more likely to be discussed separately than together in the same article. Implications for public engagement and ideological polarization are discussed.

  12. Camouflage through colour change: mechanisms, adaptive value and ecological significance

    PubMed Central

    Flores, Augusto A. V.

    2017-01-01

    Animals from a wide range of taxonomic groups are capable of colour change, of which camouflage is one of the main functions. A considerable amount of past work on this subject has investigated species capable of extremely rapid colour change (in seconds). However, relatively slow colour change (over hours, days, weeks and months), as well as changes arising via developmental plasticity are probably more common than rapid changes, yet less studied. We discuss three key areas of colour change and camouflage. First, we review the mechanisms underpinning colour change and developmental plasticity for camouflage, including cellular processes, visual feedback, hormonal control and dietary factors. Second, we discuss the adaptive value of colour change for camouflage, including the use of different camouflage types. Third, we discuss the evolutionary–ecological implications of colour change for concealment, including what it can tell us about intraspecific colour diversity, morph-specific strategies, and matching to different environments and microhabitats. Throughout, we discuss key unresolved questions and present directions for future work, and highlight how colour change facilitates camouflage among habitats and arises when animals are faced with environmental changes occurring over a range of spatial and temporal scales. This article is part of the themed issue ‘Animal coloration: production, perception, function and application’. PMID:28533459

  13. Camouflage through colour change: mechanisms, adaptive value and ecological significance.

    PubMed

    Duarte, Rafael C; Flores, Augusto A V; Stevens, Martin

    2017-07-05

    Animals from a wide range of taxonomic groups are capable of colour change, of which camouflage is one of the main functions. A considerable amount of past work on this subject has investigated species capable of extremely rapid colour change (in seconds). However, relatively slow colour change (over hours, days, weeks and months), as well as changes arising via developmental plasticity are probably more common than rapid changes, yet less studied. We discuss three key areas of colour change and camouflage. First, we review the mechanisms underpinning colour change and developmental plasticity for camouflage, including cellular processes, visual feedback, hormonal control and dietary factors. Second, we discuss the adaptive value of colour change for camouflage, including the use of different camouflage types. Third, we discuss the evolutionary-ecological implications of colour change for concealment, including what it can tell us about intraspecific colour diversity, morph-specific strategies, and matching to different environments and microhabitats. Throughout, we discuss key unresolved questions and present directions for future work, and highlight how colour change facilitates camouflage among habitats and arises when animals are faced with environmental changes occurring over a range of spatial and temporal scales.This article is part of the themed issue 'Animal coloration: production, perception, function and application'. © 2017 The Authors.

  14. The formation of galaxies

    NASA Technical Reports Server (NTRS)

    Efstathiou, G.; Silk, J.

    1983-01-01

    Current models of galaxy formation are examined in a review of recent observational and theoretical studies. Observational data on elliptical galaxies, disk galaxies, luminosity functions, clustering, and angular fluctuations in the cosmic microwave background are summarized. Theoretical aspects discussed include the origin and early evolution of small fluctuations, matter and radiation fluctuations, the formation of large-scale structure, dissipationless galaxy formation, galaxy mergers, dissipational galaxy formation, and the implications of particle physics (GUTs, massive neutrinos, and gravitinos) for cosmology.

  15. An architecture for automated fault diagnosis. [Space Station Module/Power Management And Distribution

    NASA Technical Reports Server (NTRS)

    Ashworth, Barry R.

    1989-01-01

    A description is given of the SSM/PMAD power system automation testbed, which was developed using a systems engineering approach. The architecture includes a knowledge-based system and has been successfully used in power system management and fault diagnosis. Architectural issues which effect overall system activities and performance are examined. The knowledge-based system is discussed along with its associated automation implications, and interfaces throughout the system are presented.

  16. Treatment of childhood traumatic grief.

    PubMed

    Cohen, Judith A; Mannarino, Anthony P

    2004-12-01

    Childhood traumatic grief (CTG) is a condition in which trauma symptoms impinge on children's ability to negotiate the normal grieving process. Clinical characteristics of CTG and their implications for treatment are discussed, and data from a small number of open-treatment studies of traumatically bereaved children are reviewed. An empirically derived treatment model for CTG is described; this model addresses both trauma and grief symptoms and includes a parental treatment component. Future research directions are also addressed.

  17. Gastrointestinal Bleeding in Athletes.

    PubMed

    Eichner, E R

    1989-05-01

    In brief: Gastrointestinal (GI) bleeding is a troubling yet intriguing complication of distance running. This clinical overview traces our evolving understanding of the scope and importance of GI bleeding in runners and other athletes, and discusses the diverse causes, sites, and implications of exercise-related GI bleeding. It concludes with practical tips to prevent or mitigate this problem, including gradual conditioning, avoidance of prerace aspirin intake, and when indicated, therapy with antacids, H2 blockers, or iron.

  18. Holographic dark energy with varying gravitational constant in Hořava-Lifshitz cosmology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Setare, M.R.; Jamil, Mubasher, E-mail: rezakord@ipm.ir, E-mail: mjamil@camp.nust.edu.pk

    2010-02-01

    We investigate the holographic dark energy scenario with a varying gravitational constant in a flat background in the context of Hořava-Lifshitz gravity. We extract the exact differential equation determining the evolution of the dark energy density parameter, which includes G variation term. Also we discuss a cosmological implication of our work by evaluating the dark energy equation of state for low redshifts containing varying G corrections.

  19. Migrant Adaptation - A Cross-Cultural Problem. A Review of Research on Migration, Minority Groups and Cultural Differences, with Special Regard to Children. Educational and Psychological Interactions, No. 59.

    ERIC Educational Resources Information Center

    Ekstrand, L. H.

    Research pertinent to the adaptation of immigrant children is reviewed in a cross-cultural perspective. The report focuses on research that has yielded empirical data, although a number of other papers of basic importance have been included in the review. The first chapter discusses definitions and implications of various types of cross-cultural…

  20. Four Levels of Moral Conflict in ISD

    NASA Astrophysics Data System (ADS)

    Vartiainen, Tero

    This study introduces a literature-based classification of moral conflicts in information systems development (ISD). The classification describes what moral conflicts an IS professional confronts in ISD as a whole and includes intentional, functional, managerial, and societal levels. The internal structure of moral conflicts is exemplified by means of a philosophical and a business ethics theory. The limitations of the study are considered and practical implications for the teaching of computer ethics are discussed.

  1. Pharmacodynamics of nicotine: implications for rational treatment of nicotine addiction.

    PubMed

    Benowitz, N L

    1991-05-01

    Rational treatment of the pharmacologic aspects of tobacco addiction includes nicotine substitution therapy. Understanding the pharmacodynamics of nicotine and its role in the addiction process provides a basis for rational therapeutic intervention. Pharmacodynamic considerations are discussed in relation to the elements of smoking cessation therapy: setting objectives, selecting appropriate medication and dosing form, selecting the optimal doses and dosage regimens, assessing therapeutic outcome, and adjusting therapy to optimize benefits and minimize risks.

  2. Comparison between Atlantic and Pacific Tropical Marine Coastal Ecosystems: Community Structure, Ecological Processes, and Productivity. Results and Scientific Papers of a Unesco/COMAR Workshop (Suva, Fiji, March 24-29, 1986). Unesco Reports in Marine Science 46.

    ERIC Educational Resources Information Center

    Birkeland, Charles, Ed.

    This report presents the Unesco workshop conclusions concerning important differences among tropical seas in terms of ecological processes in coastal marine ecosystems, and the corresponding implications for resource management guidelines. The conclusions result from the presentation and discussion of eight review papers which are included in this…

  3. JPL future missions and energy storage technology implications

    NASA Technical Reports Server (NTRS)

    Pawlik, Eugene V.

    1987-01-01

    The mission model for JPL future programs is presented. This model identifies mission areas where JPL is expected to have a major role and/or participate in a significant manner. These missions are focused on space science and applications missions, but they also include some participation in space station activities. The mission model is described in detail followed by a discussion on the needs for energy storage technology required to support these future activities.

  4. The Joint Milli-Arcsecond Pathfinder Survey (J-MAPS) Mission: Application for Space Situational Awareness

    DTIC Science & Technology

    2008-09-01

    One implication of this is that the instrument can physically resolve satellites at smaller separations than current and existing optical SSA assets...with the potential for 24/7 taskability and near-real time capability. By optimizing an instrument to perform position measurement rather than...sensors. The J-MAPS baseline also includes a novel filter-grating wheel, of interest in the area of non- resolved object characterization. We discuss the

  5. Implications of Drug Usage for Higher Education. Student Development Staff Papers Number One.

    ERIC Educational Resources Information Center

    Crookston, Burns B.

    This paper discusses the implications of drug usage for higher education. Drug use is not new. However, today there are several problems associated with drug usage: (1) ignorance, (2) semantics, (3) communication, and (4) change as a constant in the world. The reasons for student drug use are discussed. Students use drugs because: (1) they are…

  6. Life beyond earth and the mind of man

    NASA Technical Reports Server (NTRS)

    Berendzen, R. (Editor)

    1973-01-01

    A symposium is reported on the implications of the possibility of extraterrestrial life for social, philosophical, and humanistic impacts. The viewpoints from astronomers, biologists, physicists, anthropologists, and theologians are given. Costs involved for finding this life are discussed along with the possible benefits to society. The direct implications from radio telescopes, the Pioneer 10 plaque, and discussions between the panelists are also reported.

  7. The challenges of human population ageing

    PubMed Central

    Sander, Miriam; Oxlund, Bjarke; Jespersen, Astrid; Krasnik, Allan; Mortensen, Erik Lykke; Westendorp, Rudi Gerardus Johannes; Rasmussen, Lene Juel

    2015-01-01

    The 20th century saw an unprecedented increase in average human lifespan as well as a rapid decline in human fertility in many countries of the world. The accompanying worldwide change in demographics of human populations is linked to unanticipated and unprecedented economic, cultural, medical, social, public health and public policy challenges, whose full implications on a societal level are only just beginning to be fully appreciated. Some of these implications are discussed in this commentary, an outcome of Cultures of Health and Ageing, a conference co-sponsored by the University of Copenhagen (UCPH) and the Center for Healthy Ageing at UCPH, which took place on 20–21 June 2014 in Copenhagen, Denmark. Questions discussed here include the following: what is driving age-structural change in human populations? how can we create ‘age-friendly’ societies and promote ‘ageing-in-community’? what tools will effectively promote social engagement and prevent social detachment among older individuals? is there a risk that further extension of human lifespan would be a greater burden to the individual and to society than is warranted by the potential benefit of longer life? PMID:25452294

  8. The Association Between Masculinity and Nonsuicidal Self-Injury.

    PubMed

    Green, Jonathan D; Kearns, Jaclyn C; Ledoux, Annie M; Addis, Michael E; Marx, Brian P

    2018-01-01

    Several known risk factors for nonsuicidal self-injury (NSSI), such as negative emotionality and deficits in emotion skills, are also associated with masculinity. Researchers and clinicians suggest that masculine norms around emotional control and self-reliance may make men more likely to engage in self-harm. Masculinity has also been implicated as a potential risk factor for suicide and other self-damaging behaviors. However, the association between masculinity and NSSI has yet to be explored. In the current study, a sample of 912 emerging adults from two universities in the Northeastern United States completed a web-based questionnaire assessing adherence to masculine norms, engagement in NSSI, and known risk factors for NSSI (demographics and number of self-injurers known). Stronger adherence to masculine norms predicted chronic NSSI (five or more episodes throughout the life span) above and beyond other known risk factors. Adherence to masculine norms was related to methods of NSSI. Clinical implications are discussed, including discussions of masculine norms in treatment settings. Future research should examine what specific masculine norms are most closely linked to NSSI and other self-damaging behaviors.

  9. Protein glycosylation in gastric and colorectal cancers: Toward cancer detection and targeted therapeutics.

    PubMed

    Ferreira, José Alexandre; Magalhães, Ana; Gomes, Joana; Peixoto, Andreia; Gaiteiro, Cristiana; Fernandes, Elisabete; Santos, Lúcio Lara; Reis, Celso A

    2017-02-28

    Glycosylation is the most frequent and structurally complex posttranslational modification in cell-surface and secreted proteins. Glycans are major orchestrators of biological processes, namely, by controlling protein folding and key biological functions such as cell adhesion, migration, signaling and immune recognition. Altered glycosylation is considered a hallmark of malignant transformations that decisively contributes to disease outcome. This review comprehensively summarizes the main findings related with gastrointestinal cancers and the decisive impact of aberrant glycosylation on tumor biology toward more aggressive phenotypes. Particular emphasis is given to alterations in O-glycosylation, namely, the overexpression of immature O-glycans, and the sialylated Lewis antigens sialyl-LeA and sialyl-LeX, frequently implicated in lymphohematogenous metastasis. We further discuss how recent contributions from glycoproteomics and glycoengineering fields have broadened our understanding of the human O-glycoproteome and its implications for cancer research. Finally, we address the tremendous potential of glycans in the context of targeted therapeutics (selective inhibition of glycosylation pathways, immunotherapy) and discuss the need to include glycomics/glycoproteomics in holistic panomics models toward true precision medicine settings. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  10. [Suspension of Respiratory Support in Patients with Amyotrophic Lateral Sclerosis].

    PubMed

    Silberberg, Agustín A; Robetto, Josefina; Achával, Mora

    2018-01-01

    Decision making in advanced Amyotrophic Lateral Sclerosis (ALS) patients keeps on being a controversial issue. The aim of this work is to discuss ethical implications of withdrawing respiratory support treatment in patients with ALS. Through a bibliographic search on Pubmed database (2010-2016) we investigated whether or not the use of Non-Invasive Ventilation (NIV) and Mechanical Ventilation (MV) would increase survival and quality of life. We included 38 review articles. From these papers, results and ethical implications of initiating and mainly withdrawing respiratory support were analyzed. Survival time increased with NIV and with MV. Quality of life, above all according to physiological criteria, improved with NIV but regarding MV it remained controversial. Implementation and future withdrawal of MV seemed open to medical and ethical discussion. From a perspective of the intrinsic dignity of every human being, whatever its quality of life was, and knowing that no effective therapies for the underlying disease are available, the decision to remove MV in a patient with advanced ALS requires: knowledge of the will of the patient and, above all, evaluating whether this respiratory support measure is becoming objectively disproportionate.

  11. Exploring the differences between pet and non-pet owners: Implications for human-animal interaction research and policy

    PubMed Central

    Saunders, Jessica; Parast, Layla; Babey, Susan H.; Miles, Jeremy V.

    2017-01-01

    There is conflicting evidence about whether living with pets results in better mental and physical health outcomes, with the majority of the empirical research evidence being inconclusive due to methodological limitations. We briefly review the research evidence, including the hypothesized mechanisms through which pet ownership may influence health outcomes. This study examines how pet and non-pet owners differ across a variety of socio-demographic and health measures, which has implications for the proper interpretation of a large number of correlational studies that attempt to draw causal attributions. We use a large, population-based survey from California administered in 2003 (n = 42,044) and find that pet owners and non-pet owners differ across many traits, including gender, age, race/ethnicity, living arrangements, and income. We include a discussion about how the factors associated with the selection into the pet ownership group are related to a range of mental and physical health outcomes. Finally, we provide guidance on how to properly model the effects of pet ownership on health to accurately estimate this relationship in the general population. PMID:28644848

  12. Thermo-optically induced interactions in photon Bose-Einstein Condensates

    NASA Astrophysics Data System (ADS)

    Alaeian, Hadiseh; Bartels, Clara; Weitz, Martin

    Bose-Einstein condensation (BEC), a new state of matter, emerges when the de Broglie wavelength of bosons becomes larger than the particle separation, leading to a macroscopic occupation of the system ground state. Followed by the first experimental demonstrations of BEC in cold atomic gases, this phase transition has been observed in other bosonic gases, as polaritons and phonons. The most recent one, photon BEC, is a promising candidate for a new generation of coherent photon sources. Due to their infancy, however, many of their properties are still unknown or only partly explored. In this talk I will present my latest results on the implications of photon interactions in photon BECs. In particular, I will investigate the effect of a thermo-optic non-linearity, leading to spatially non-local and delayed interactions. Starting from the steady state behavior, I will explore the spectrum of elementary excitations as a small perturbation. Moreover, I will discuss the resulting effective photon dispersion, manifesting various properties including possible superfluidity, as well as roton and maxon modes. The implications of physical parameters as absorption, number of photons in the condensate, and cavity trap on the dispersion will be discussed. The results of this study shed new light on the implication of interactions in photonic many-body systems. Hadiseh Alaeian acknowledges the generous support from Alexander von Humboldt Foundation.

  13. Hypertext, Hypermedia, and Metacognition: Research and Instructional Implications for Disabled Readers.

    ERIC Educational Resources Information Center

    Balajthy, Ernest

    1990-01-01

    The article examines the potential impact of computer-based text technologies, called hypermedia, on disabled readers. Discussed are hypertext, the hypercard, and implications of metacognitive research (such as author versus user control over text manipulations), instructional implications, and instructional text engineering. (DB)

  14. The Microchip Revolution: Implications for Education.

    ERIC Educational Resources Information Center

    Small, Michele Geslin

    1984-01-01

    Discusses positive and negative implications of microcomputer technology for teachers and students; how this technology will facilitate barrier breakdown between school and society; possible political implications; and how the principles of anticipation, design, and planning will facilitate a smooth transitional course in school and society. (MBR)

  15. Emerging issues with mentally ill offenders: causes and social consequences.

    PubMed

    Rock, M

    2001-01-01

    Persons with mental illness and co-occurring substance abuse disorders are incarcerated at disproportionately high rates in comparison to the general population. Reasons may include high standards for involuntary commitment, an overall increase in substance abuse and the policy of deinstitutionalization. However, one significant reason may be that psychiatric institutions serve a social control function, which has not been appreciated by policymakers and program developers since deinstitutionalization. This paper presents provider views of the population and issues of concern for clients, families, and the agencies. Discussion includes service-provider response to the population, new program models, and implications for policymakers.

  16. Modeling of materials supply, demand and prices

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The societal, economic, and policy tradeoffs associated with materials processing and utilization, are discussed. The materials system provides the materials engineer with the system analysis required for formulate sound materials processing, utilization, and resource development policies and strategies. Materials system simulation and modeling research program including assessments of materials substitution dynamics, public policy implications, and materials process economics was expanded. This effort includes several collaborative programs with materials engineers, economists, and policy analysts. The technical and socioeconomic issues of materials recycling, input-output analysis, and technological change and productivity are examined. The major thrust areas in materials systems research are outlined.

  17. Comparing the effects of massed and distributed practice on skill acquisition for children with autism.

    PubMed

    Haq, Shaji S; Kodak, Tiffany; Kurtz-Nelson, Evangeline; Porritt, Marilynn; Rush, Kristin; Cariveau, Tom

    2015-01-01

    We replicated and extended the findings of Haq and Kodak (2015) by evaluating the efficiency of massed and distributed practice for teaching tacts and textual and intraverbal behavior to 3 children with autism. Massed practice included all practice opportunities conducted on 1 day during each week, and distributed practice included practice opportunities conducted across several days during the week. The results indicated that distributed practice was more efficient for all participants. Suggested areas for future research and implications for practice are discussed. © Society for the Experimental Analysis of Behavior.

  18. eHealth interventions for HIV prevention

    PubMed Central

    Noar, Seth M.; Willoughby, Jessica Fitts

    2015-01-01

    The rapidly changing media landscape and proliferation of new technologies creates vast new opportunities for HIV prevention. The fast growth of the relatively new eHealth field is a testament to the excitement and promise of these new technologies. eHealth interventions in HIV prevention tested to date include computer- and Internet-based interventions; chat room interventions; text messaging interventions; and social media. The current article provides a brief review of these types of interventions in HIV prevention, including their unique advantages and evidence of efficacy. Implications for future research in the eHealth HIV prevention field are discussed. PMID:22519523

  19. South Asian women's coping strategies in the face of domestic violence in the United States.

    PubMed

    Bhandari, Shreya

    2018-02-01

    We conducted in-depth telephone interviews with a convenience sample of 20 South Asian women experiencing domestic violence in the United States. Utilizing the emotion-focused and problem-focused coping framework, the researchers analyzed the narratives of abused South Asian women. Emotion-focused coping strategies include (a) spirituality and/or religion and (b) the role of children. Problem-focused coping strategies include (c) informal and formal support and (d) strategies of resisting, pacifying, safety planning. Implications for practice and future research in the United States and internationally are discussed.

  20. Living with Ankylosing Spondylitis: the patient's perspective.

    PubMed

    Hamilton-West, Kate E; Quine, Lyn

    2009-09-01

    Ankylosing Spondylitis (AS) is a potentially debilitating chronic condition that necessitates a biopsychosocial approach for successful long-term management. However, the psychosocial consequences of AS are not well understood. In this study patients (N = 68) reported impacts of AS across a wide range of life domains; negative impacts included physical effects of AS, changes in mood or personality, effects on social life and relationships with friends and family, low self-esteem, stigma and worry about the future; positive impacts included increased exercise, feelings of achievement and empathy, stronger relationships, slower pace of life and a more positive perspective. Implications for treatment are discussed.

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