LDR system concepts and technology

NASA Technical Reports Server (NTRS)

Pittman, B.

1985-01-01

The Large Deployable Reflector is a 20 meter diameter infrared/submillimeter telescope planned for the late 1990's. The Astronomy Survey Committee of the National Academy of Sciences (Field Committee) recommended LDR as one of the two space based observatories that should start development in the 80's. LDR's large aperture will give it unequaled resolution in the wavelength range from 30 to 1000 microns. To meet LDR performance goals will call for advances in several technology disciplines including: optics, controls, thermal control, detectors, cryogenic cooling, and large space structures.

75 FR 65482 - Approval of a Petition for Exemption From Hazardous Waste Disposal Injection Restrictions to...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-25

... Waste Disposal Injection Restrictions to ArcelorMittal Burns Harbor, LLC, Burns Harbor, IN AGENCY... by the United States Environmental Protection Agency (EPA) that an exemption to the land disposal restrictions under the 1984 Hazardous and Solid Waste Amendments (HSWA) to the Resource Conservation and...

LDR cryogenics

NASA Technical Reports Server (NTRS)

Nast, T.

1988-01-01

A brief summary from the 1985 Large Deployable Reflector (LDR) Asilomar 2 workshop of the requirements for LDR cryogenic cooling is presented. The heat rates are simply the sum of the individual heat rates from the instruments. Consideration of duty cycle will have a dramatic effect on cooling requirements. There are many possible combinations of cooling techniques for each of the three temperatures zones. It is clear that much further system study is needed to determine what type of cooling system is required (He-2, hybrid or mechanical) and what size and power is required. As the instruments, along with their duty cycles and heat rates, become better defined it will be possible to better determine the optimum cooling systems.

Large Deployable Reflector (LDR) feasibility study update

NASA Technical Reports Server (NTRS)

Alff, W. H.; Banderman, L. W.

1983-01-01

In 1982 a workshop was held to refine the science rationale for large deployable reflectors (LDR) and develop technology requirements that support the science rationale. At the end of the workshop, a set of LDR consensus systems requirements was established. The subject study was undertaken to update the initial LDR study using the new systems requirements. The study included mirror materials selection and configuration, thermal analysis, structural concept definition and analysis, dynamic control analysis and recommendations for further study. The primary emphasis was on the dynamic controls requirements and the sophistication of the controls system needed to meet LDR performance goals.

Leucine disposal rate for assessment of amino acid metabolism in maintenance hemodialysis patients.

PubMed

Denny, Gerald B; Deger, Serpil M; Chen, Guanhua; Bian, Aihua; Sha, Feng; Booker, Cindy; Kesler, Jaclyn T; David, Sthuthi; Ellis, Charles D; Ikizler, T Alp

Protein energy wasting (PEW) is common in patients undergoing maintenance hemodialysis (MHD) and closely associated with poor outcomes. Insulin resistance and associated alterations in amino acid metabolism are potential pathways leading to PEW. We hypothesized that the measurement of leucine disposal during a hyperinsulinemic- euglycemic-euaminoacidemic clamp (HEAC) procedure would accurately measure the sensitivity to insulin for its actions on concomitant carbohydrate and protein metabolism in MHD patients. We examined 35 MHD patients and 17 control subjects with normal kidney function by hyperinsulinemic-euglycemic clamp (HEGC) followed by HEAC clamp procedure to obtain leucine disposal rate (LDR) along with isotope tracer methodology to assess whole body protein turnover. The glucose disposal rate (GDR) by HEGC was 5.1 ± 2.1 mg/kg/min for the MHD patients compared to 6.3 ± 3.9 mg/kg/min for the controls ( p = 0.38). The LDR during HEAC was 0.09 ± 0.03 mg/kg/min for the MHD patients compared to 0.11 ± 0.05 mg/kg/min for the controls ( p = 0.009). The LDR level was correlated with whole body protein synthesis ( r = 0.25; p = 0.08), with whole body protein breakdown ( r = -0.38 p = 0.01) and net protein balance ( r = 0.85; p < 0.001) in the overall study population. Correlations remained significant in subgroup analysis. The GDR derived by HEGC and LDR correlated well in the controls ( r = 0.79, p < 0.001), but less so in the MHD patients ( r = 0.58, p < 0.001). Leucine disposal rate reliably measures amino acid utilization in MHD patients and controls in response to high dose insulin.

Cryogenics for LDR

NASA Technical Reports Server (NTRS)

Kittel, Peter

1988-01-01

Three cryogenic questions of importance to Large Deployable Reflector (LDR) are discussed: the primary cooling requirement, the secondary cooling requirement, and the instrument changeout requirement.

Report of the Asilomar 3 LDR Workshop

NASA Technical Reports Server (NTRS)

Mahoney, M. J. (Editor)

1988-01-01

The conclusions and recommendations of the workshop held to study technology development issues critical to the Large Deployable Reflector (LDR) are summarized. LDR is to be a dedicated, orbiting, astronomical observatory, operating at wavelengths from 30 to 1000 microns, a spectral region where the Earth's atmosphere is almost completely opaque. Because it will have a large, segmented, passively cooled aperture, LDR addresses a wide range of technology areas. These include lightweight, low cost, structural composite reflector panels, primary support structures, wavefront sensing and adaptive optics, thermal background management, and integrated vibration and pointing control systems. The science objectives for LDR present instrument development challenges for coherent and direct arrayed detectors which can operate effectively at far infrared and submillimeter wavelengths, and for sub-Kelvin cryogenic systems.

Large Deployable Reflector (LDR) system concept and technology definition study. Analysis of space station requirements for LDR

NASA Technical Reports Server (NTRS)

Agnew, Donald L.; Vinkey, Victor F.; Runge, Fritz C.

1989-01-01

A study was conducted to determine how the Large Deployable Reflector (LDR) might benefit from the use of the space station for assembly, checkout, deployment, servicing, refurbishment, and technology development. Requirements that must be met by the space station to supply benefits for a selected scenario are summarized. Quantitative and qualitative data are supplied. Space station requirements for LDR which may be utilized by other missions are identified. A technology development mission for LDR is outlined and requirements summarized. A preliminary experiment plan is included. Space Station Data Base SAA 0020 and TDM 2411 are updated.

Large Deployable Reflector (LDR) system concept and technology definition study. Analysis of space station requirements for LDR

NASA Astrophysics Data System (ADS)

Agnew, Donald L.; Vinkey, Victor F.; Runge, Fritz C.

1989-04-01

A study was conducted to determine how the Large Deployable Reflector (LDR) might benefit from the use of the space station for assembly, checkout, deployment, servicing, refurbishment, and technology development. Requirements that must be met by the space station to supply benefits for a selected scenario are summarized. Quantitative and qualitative data are supplied. Space station requirements for LDR which may be utilized by other missions are identified. A technology development mission for LDR is outlined and requirements summarized. A preliminary experiment plan is included. Space Station Data Base SAA 0020 and TDM 2411 are updated.

Leucine disposal rate for assessment of amino acid metabolism in maintenance hemodialysis patients

PubMed Central

Denny, Gerald B.; Deger, Serpil M.; Chen, Guanhua; Bian, Aihua; Sha, Feng; Booker, Cindy; Kesler, Jaclyn T.; David, Sthuthi; Ellis, Charles D.; Ikizler, T. Alp

2016-01-01

Background Protein energy wasting (PEW) is common in patients undergoing maintenance hemodialysis (MHD) and closely associated with poor outcomes. Insulin resistance and associated alterations in amino acid metabolism are potential pathways leading to PEW. We hypothesized that the measurement of leucine disposal during a hyperinsulinemic- euglycemic-euaminoacidemic clamp (HEAC) procedure would accurately measure the sensitivity to insulin for its actions on concomitant carbohydrate and protein metabolism in MHD patients. Methods We examined 35 MHD patients and 17 control subjects with normal kidney function by hyperinsulinemic-euglycemic clamp (HEGC) followed by HEAC clamp procedure to obtain leucine disposal rate (LDR) along with isotope tracer methodology to assess whole body protein turnover. Results The glucose disposal rate (GDR) by HEGC was 5.1 ± 2.1 mg/kg/min for the MHD patients compared to 6.3 ± 3.9 mg/kg/min for the controls (p = 0.38). The LDR during HEAC was 0.09 ± 0.03 mg/kg/min for the MHD patients compared to 0.11 ± 0.05 mg/kg/min for the controls (p = 0.009). The LDR level was correlated with whole body protein synthesis (r = 0.25; p = 0.08), with whole body protein breakdown (r = −0.38 p = 0.01) and net protein balance (r = 0.85; p < 0.001) in the overall study population. Correlations remained significant in subgroup analysis. The GDR derived by HEGC and LDR correlated well in the controls (r = 0.79, p < 0.001), but less so in the MHD patients (r = 0.58, p < 0.001). Conclusions Leucine disposal rate reliably measures amino acid utilization in MHD patients and controls in response to high dose insulin. PMID:27413537

1999 Report on Hanford Site land disposal restriction for mixed waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

BLACK, D.G.

This report was submitted to meet the requirements of Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) Milestone M-26-011. This milestone requires the preparation of an annual report that covers characterization, treatment, storage, minimization, and other aspects of managing land-disposal-restricted mixed waste at the Hanford Facility.

Special Consolidated Checklists for Land Disposal Restrictions (unchanged since 1992)

EPA Pesticide Factsheets

This checklist consolidates LDR rules from the first rule promulgated on November 7, 1986 through June 30, 1992, including the Third Third Scheduled wastes (i.e., from Revision Checklist 34 through Revision Checklist 106, 57 FR 28628, June 26, 1992).

LDR: A submillimeter great observatory

NASA Astrophysics Data System (ADS)

Wilson, Robert

1990-12-01

The Large Deployable Reflector (LDR), a high Earth orbit free flying 10 to 20 m diameter deployable telescope, is described. The LDR is intended for use throughout the submillimeter band, using imaging receivers with unprecedented sensitivity and angular resolution. Its mission is to produce pictures of line emission regions in the solar neighborhood, in nearby galaxies and in objects at the edge of the known galaxy distribution. It is predicted to be an ideal instrument for exploring the first galaxies and protogalaxies as the submillimeter cooling lines should light up as soon as metals form.

LDR structural technology activities at JPL

NASA Technical Reports Server (NTRS)

Wada, Ben

1988-01-01

The status of the Large Deployable Reflector (LDR) technology requirements and the availability of that technology in the next few years are summarized. The research efforts at JPL related to these technology needs are also discussed. LDR requires that a large and relatively stiff truss-type backup structure have a surface accurate to 100 microns in space (initial position with thermal distortions) and the dynamic characteristics predictable and/or measurable by on-orbit system identification for micron level motion. This motion may result from the excitation of the lower modes or from wave-type motions. It is also assumed that the LDR structure can be ground tested to validate its ability to meet mission requirements. No program manager will commit a structural design based solely on analysis, unless the analysis is backed by a validation test program.

Large Deployable Reflector (LDR) Requirements for Space Station Accommodations

NASA Technical Reports Server (NTRS)

Crowe, D. A.; Clayton, M. J.; Runge, F. C.

1985-01-01

Top level requirements for assembly and integration of the Large Deployable Reflector (LDR) Observatory at the Space Station are examined. Concepts are currently under study for LDR which will provide a sequel to the Infrared Astronomy Satellite and the Space Infrared Telescope Facility. LDR will provide a spectacular capability over a very broad spectral range. The Space Station will provide an essential facility for the initial assembly and check out of LDR, as well as a necessary base for refurbishment, repair and modification. By providing a manned platform, the Space Station will remove the time constraint on assembly associated with use of the Shuttle alone. Personnel safety during necessary EVA is enhanced by the presence of the manned facility.

Large Deployable Reflector (LDR) requirements for space station accommodations

NASA Astrophysics Data System (ADS)

Crowe, D. A.; Clayton, M. J.; Runge, F. C.

1985-04-01

Top level requirements for assembly and integration of the Large Deployable Reflector (LDR) Observatory at the Space Station are examined. Concepts are currently under study for LDR which will provide a sequel to the Infrared Astronomy Satellite and the Space Infrared Telescope Facility. LDR will provide a spectacular capability over a very broad spectral range. The Space Station will provide an essential facility for the initial assembly and check out of LDR, as well as a necessary base for refurbishment, repair and modification. By providing a manned platform, the Space Station will remove the time constraint on assembly associated with use of the Shuttle alone. Personnel safety during necessary EVA is enhanced by the presence of the manned facility.

Changes of Space Debris Orbits After LDR Operation

NASA Astrophysics Data System (ADS)

Wnuk, E.; Golebiewska, J.; Jacquelard, C.; Haag, H.

2013-09-01

A lot of technical studies are currently developing concepts of active removal of space debris to protect space assets from on orbit collision. For small objects, such concepts include the use of ground-based lasers to remove or reduce the momentum of the objects thereby lowering their orbit in order to facilitate their decay by re-entry into the Earth's atmosphere. The concept of the Laser Debris Removal (LDR) system is the main subject of the CLEANSPACE project. One of the CLEANSPACE objectives is to define a global architecture (including surveillance, identification and tracking) for an innovative ground-based laser solution, which can remove hazardous medium debris around selected space assets. The CLEANSPACE project is realized by a European consortium in the frame of the European Commission Seventh Framework Programme (FP7), Space topic. The use of sequence of laser operations to remove space debris, needs very precise predictions of future space debris orbital positions, on a level even better than 1 meter. Orbit determination, tracking (radar, optical and laser) and orbit prediction have to be performed with accuracy much better than so far. For that, the applied prediction tools have to take into account all perturbation factors that influence object orbit. The expected object's trajectory after the LDR operation is a lowering of its perigee. To prevent the debris with this new trajectory to collide with another object, a precise trajectory prediction after the LDR sequence is therefore the main task allowing also to estimate re-entry parameters. The LDR laser pulses change the debris object velocity v. The future orbit and re-entry parameters of the space debris after the LDR engagement can be calculated if the resulting ?v vector is known with the sufficient accuracy. The value of the ?v may be estimated from the parameters of the LDR station and from the characteristics of the orbital debris. However, usually due to the poor knowledge of the debris

PCR/LDR/capillary electrophoresis for detection of single-nucleotide differences between fetal and maternal DNA in maternal plasma.

PubMed

Yi, Ping; Chen, Zhuqin; Zhao, Yan; Guo, Jianxin; Fu, Huabin; Zhou, Yuanguo; Yu, Lili; Li, Li

2009-03-01

The discovery of fetal DNA in maternal plasma has opened up an approach for noninvasive diagnosis. We have now assessed the possibility of detecting single-nucleotide differences between fetal and maternal DNA in maternal plasma by polymerase chain reaction (PCR)/ligase detection reaction((LDR)/capillary electrophoresis. PCR/LDR/capillary electrophoresis was applied to detect the genotype of c.454-397T>gene (ESR1) from experimental DNA models of maternal plasma at different sensitivity levels and 13 maternal plasma samples.alphaC in estrogen receptor. (1) Our results demonstrated that the technique could discriminate low abundance single-nucleotide mutation with a mutant/normal allele ratio up to 1:10 000. (2) Examination of ESR1 c.454-397T>C genotypes by using the method of restriction fragment length analysis was performed in 25 pregnant women, of whom 13 pregnant women had homozygous genotypes. The c.454-397T>C genotypes of paternally inherited fetal DNA in maternal plasma of these 13 women were detected by PCR/LDR/capillary electrophoresis, which were accordant with the results of umbilical cord blood. PCR/LDR/capillary electrophoresis has very high sensitivity to distinguish low abundance single nucleotide differences and can discriminate point mutations and single-nucleotide polymorphisms(SNPs) of paternally inherited fetal DNA in maternal plasma.

Low-dose radiation (LDR) induces hematopoietic hormesis: LDR-induced mobilization of hematopoietic progenitor cells into peripheral blood circulation.

PubMed

Li, Wei; Wang, Guanjun; Cui, Jiuwei; Xue, Lu; Cai, Lu

2004-11-01

The aim of this study was to investigate the stimulating effect of low-dose radiation (LDR) on bone marrow hematopoietic progenitor cell (HPC) proliferation and peripheral blood mobilization. Mice were exposed to 25- to 100-mGy x-rays. Bone marrow and peripheral blood HPCs (BFU-E, CFU-GM, and c-kit+ cells) were measured, and GM-CSF, G-CSF, and IL-3 protein and mRNA expression were detected using ELISA, slot blot hybridization, and Northern blot methods. To functionally evaluate LDR-stimulated and -mobilized HPCs, repopulation of peripheral blood cells in lethally irradiated recipients after transplantation of LDR-treated donor HPCs was examined by WBC counts, animal survival, and colony-forming units in the recipient spleens (CFUs-S). 75-mGy x-rays induced a maximal stimulation for bone marrow HPC proliferation (CFU-GM and BFU-E formation) 48 hours postirradiation, along with a significant increase in HPC mobilization into peripheral blood 48 to 72 hours postradiation, as shown by increases in CFU-GM formation and proportion of c-kit+ cells in the peripheral mononuclear cells. 75-mGy x-rays also maximally induced increases in G-CSF and GM-CSF mRNA expression in splenocytes and levels of serum GM-CSF. To define the critical role of these hematopoietic-stimulating factors in HPC peripheral mobilization, direct administration of G-CSF at a dose of 300 microg/kg/day or 150 microg/kg/day was applied and found to significantly stimulate GM-CFU formation and increase c-kit+ cells in the peripheral mononuclear cells. More importantly, 75-mGy x-rays plus 150 microg/kg/day G-CSF (LDR/150-G-CSF) produced a similar effect to that of 300 microg/kg/day G-CSF alone. Furthermore, the capability of LDR-mobilized donor HPCs to repopulate blood cells was confirmed in lethally irradiated recipient mice by counting peripheral WBC and CFUs-S. These results suggest that LDR induces hematopoietic hormesis, as demonstrated by HPC proliferation and peripheral mobilization, providing a

Structural design of the Large Deployable Reflector (LDR)

NASA Technical Reports Server (NTRS)

Satter, Celeste M.; Lou, Michael C.

1991-01-01

An integrated Large Deployable Reflector (LDR) analysis model was developed to enable studies of system responses to the mechanical and thermal disturbances anticipated during on-orbit operations. Functional requirements of the major subsystems of the LDR are investigated, design trades are conducted, and design options are proposed. System mass and inertia properties are computed in order to estimate environmental disturbances, and in the sizing of control system hardware. Scaled system characteristics are derived for use in evaluating launch capabilities and achievable orbits. It is concluded that a completely passive 20-m primary appears feasible for the LDR from the standpoint of both mechanical vibration and thermal distortions.

Structural design of the Large Deployable Reflector (LDR)

NASA Astrophysics Data System (ADS)

Satter, Celeste M.; Lou, Michael C.

1991-09-01

An integrated Large Deployable Reflector (LDR) analysis model was developed to enable studies of system responses to the mechanical and thermal disturbances anticipated during on-orbit operations. Functional requirements of the major subsystems of the LDR are investigated, design trades are conducted, and design options are proposed. System mass and inertia properties are computed in order to estimate environmental disturbances, and in the sizing of control system hardware. Scaled system characteristics are derived for use in evaluating launch capabilities and achievable orbits. It is concluded that a completely passive 20-m primary appears feasible for the LDR from the standpoint of both mechanical vibration and thermal distortions.

Workshop on Technology Development Issues for the Large Deployable Reflector (LDR)

NASA Technical Reports Server (NTRS)

Nishioka, Kenji (Editor)

1986-01-01

The results of the 2nd Large Deployable Reflector (LDR) Technology Review Workshop held at Asilomar, California, March 17 to 22, 1985, are summarized. The workshop was convened to update LDR Technology status and to revise as necessary the results for the first LDR Workshop held in June 1982. There were some 100 participants representing government agencies, industry, and universities. This Workshop's goal was to assess, identify, and set priorities for the LDR technology issues based on requirements identified in the first workshop. Four high-priority technology areas were identified: (1) mirror materials and construction; (2) sensing and controls; (3) system-simulation and modeling capability; and (4) submillimeter instruments. The results of the workshop were used to provide a list of technolgy issues for the development of a technology initiatives plan for the LDR by NASA's Office of Aeronautics and Space Technology.

Calculation of Hazardous Waste Land Disposal Restrictions (LDR) Treatment Standards

EPA Pesticide Factsheets

examples of calculations of treatment standards including for High Concentration Selenium Wastes Using Data Submitted by Chemical Waste Management (CWM) and Antimony Using Data Submitted by Chemical Waste Management and Data Obtained From Rollins.

The Large Deployable Reflector (LDR) report of the Science Coordination Group

NASA Technical Reports Server (NTRS)

1986-01-01

The Large Deployable Reflector (LDR) is a telescope designed to carry out high-angular resolution, high-sensitivity observations at far-infrared and submillimeter wavelengths. The scientific rationale for the LDR is discussed in light of the recent Infrared Astronomical Satellite (IRAS) and Kuiper Airborne Observatory (KAO) results and the several new ground-based observatories planned for the late 1980s. The importance of high sensitivity and high angular resolution observations from space in the submillimeter region is stressed. The scientific and technical problems of using the LDR in a light bucket mode at approx. less than 5 microns and in designing the LDR as an unfilled aperture with subarcsecond resolution are also discussed. The need for an aperture as large as 20 m is established, along with the requirements of beam-shape stability, spatial chopping, thermal control, and surface figure stability. The instrument complement required to cover the wavelength-spectral resolution region of interest to the LDR is defined.

Diffraction, chopping, and background subtraction for LDR

NASA Technical Reports Server (NTRS)

Wright, Edward L.

1988-01-01

The Large Deployable Reflector (LDR) will be an extremely sensitive infrared telescope if the noise due to the photons in the large thermal background is the only limiting factor. For observations with a 3 arcsec aperture in a broadband at 100 micrometers, a 20-meter LDR will emit 10(exp 12) per second, while the photon noise limited sensitivity in a deep survey observation will be 3,000 photons per second. Thus the background subtraction has to work at the 1 part per billion level. Very small amounts of scattered or diffracted energy can be significant if they are modulated by the chopper. The results are presented for 1-D and 2-D diffraction calculations for the lightweight, low-cost LDR concept that uses an active chopping quaternary to correct the wavefront errors introduced by the primary. Fourier transforms were used to evaluate the diffraction of 1 mm waves through this system. Unbalanced signals due to dust and thermal gradients were also studied.

Effect of central obscuration on the LDR point spread function

NASA Technical Reports Server (NTRS)

Vanzyl, Jakob J.

1988-01-01

It is well known that Gaussian apodization of an aperture reduces the sidelobe levels of its point spread function (PSF). In the limit where the standard deviation of the Gaussian function is much smaller than the diameter of the aperture, the sidelobes completely disappear. However, when Gaussian apodization is applied to the Large Deployable Reflector (LDR) array consisting of 84 hexagonal panels, it is found that the sidelobe level only decreases by about 2.5 dB. The reason for this is explained. The PSF is shown for an array consisting of 91 uniformly illuminated hexagonal apertures; this array is identical to the LDR array, except that the central hole in the LDR array is filled with seven additional panels. For comparison, the PSF of the uniformly illuminated LDR array is shown. Notice that it is already evident that the sidelobe structure of the LDR array is different from that of the full array of 91 panels. The PSF's of the same two arrays are shown, but with the illumination apodized with a Gaussian function to have 20 dB tapering at the edges of the arrays. While the sidelobes of the full array have decreased dramatically, those of the LDR array changed in structure, but stayed at almost the same level. This result is not completely surprising, since the Gaussian apodization tends to emphasize the contributions from the central portion of the array; exactly where the hole in the LDR array is located. The two most important conclusions are: the size of the central hole should be minimized, and a simple Gaussian apodization scheme to suppress the sidelobes in the PSF should not be used. A more suitable apodization scheme would be a Gaussian annular ring.

7 CFR 319.37 - Prohibitions and restrictions on importation; disposal of articles refused importation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 5 2011-01-01 2011-01-01 false Prohibitions and restrictions on importation; disposal of articles refused importation. 319.37 Section 319.37 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Nursery Stock, Plants, Root...

7 CFR 319.37 - Prohibitions and restrictions on importation; disposal of articles refused importation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Prohibitions and restrictions on importation; disposal of articles refused importation. 319.37 Section 319.37 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Nursery Stock, Plants, Root...

Optimal conditions of LDR to protect the kidney from diabetes

PubMed Central

Cheng, Jie; Li, Fengsheng; Cui, Jiuwei; Guo, Weiying; Li, Cai; Li, Wei; Wang, Guixia; Xing, Xiao; Gao, Ying; Ge, Yuanyuan; Wang, Guanjun; Cai, Lu

2014-01-01

Aims We reported the attenuation of diabetes-induced renal dysfunction by exposure to multiple low-dose radiation (LDR) at 25 mGy every other day via suppressing renal oxidative damage. We here explored the optimal conditions of LDR to protect the kidney from diabetes. Main methods Type 1 diabetic mice were induced with multiple injections of low-dose streptozotocin in male C57BL/6J mice. Diabetic mice received whole body X-irradiation at dose of 12.5, 25 or 50 mGy every other day for either 4 or 8 weeks. Age-matched normal mice were similarly irradiated at the dose of 25 mGy for 4 or 8 weeks. The renal function and histopathological changes were examined at the 4th and 8th week of the study. Key findings Diabetes induced renal dysfunction, shown by the decreased creatinine and increased microalbumin in urinary. Renal oxidative damage, detected by protein nitration and lipid oxidation, and remodeling, reflected by increased expression of connective tissue growth factor, collagen IV and fibronectin, were significantly increased in diabetic mice. All these renal pathological and function changes in diabetic mice were significantly attenuated by exposure to LDR at all regimens, among which, however, exposure to LDR at 12.5 mGy for 8 weeks provided the best preventive effect on the kidney of diabetic mice. Significance Our results suggest that whole-body LDR at 12.5 mGy every other day for 8 weeks is the optimal condition of LDR to protect the kidney from diabetes. PMID:24631139

40 CFR 266.210 - What definitions apply to this subpart?

Code of Federal Regulations, 2010 CFR

2010-07-01

... waste described in 40 CFR 261.3. Hazardous Waste means any material which is defined to be hazardous waste in accordance with 40 CFR 261.3, “Definition of Hazardous Waste.” Land Disposal Restriction (LDR...

Introduction to the report of the Asilomar 3 LDR workshop

NASA Technical Reports Server (NTRS)

1988-01-01

The Large Deployable Reflector (LDR) is a system concept for a dedicated, orbiting, submillimeter, far infrared, astronomical observatory. The purpose of the 3rd conference was to review the latest system concepts for LDR, update the science requirements, and assess the status of the technology development that was recommended at Asilomar 2. The technology development assessment included ongoing work within NASA, the DOD, and various universities. Problem areas and technologies not being adequately addressed were to be identified and prioritized. In particular, the CSTI program in Sensors and Precision Segmented Reflectors was reviewed for appropriateness and progress relative to LDR technology needs.

37 CFR 7.24 - Requests to record security interest or other restriction of holder's rights of disposal or...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Requests to record security interest or other restriction of holder's rights of disposal or release of such restriction submitted through the Office. 7.24 Section 7.24 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF...

LDR structural experiment definition

NASA Technical Reports Server (NTRS)

Russell, Richard A.; Gates, Richard M.

1988-01-01

A study was performed to develop the definition of a structural flight experiment for a large precision segmented reflector that would utilize the Space Station. The objective of the study was to use the Large Deployable Reflector (LDR) baseline configuration for focusing on experiment definition activity which would identify the Space Station accommodation requirements and interface constraints. Results of the study defined three Space Station based experiments to demonstrate the technologies needed for an LDR type structure. The basic experiment configurations are the same as the JPL baseline except that the primary mirror truss is 10 meters in diameter instead of 20. The primary objectives of the first experiment are to construct the primary mirror support truss and to determine its structural and thermal characteristics. Addition of the optical bench, thermal shield and primary mirror segments and alignment of the optical components occur on the second experiment. The structure will then be moved to the payload pointing system for pointing, optical control and scientific optical measurement for the third experiment.

Intervening to promote early initiation of breastfeeding in the LDR.

PubMed

Komara, Carol; Simpson, Diana; Teasdale, Carla; Whalen, Gaye; Bell, Shay; Giovanetto, Laurie

2007-01-01

To evaluate the effectiveness of an interventional protocol for the early initiation of breastfeeding that would remove barriers in the labor, delivery, recovery (LDR) unit. Descriptive design using 100 postpartum mothers who were interviewed before discharge at a large university hospital in the south-central United States. Descriptive statistics were used for analysis. The protocol was effective for initiating breastfeeding, and breastfeeding increased from 53% to 66%. When barriers to breastfeeding are reduced in the LDR setting, women will breastfeed. It is possible that reducing hospital barriers to breastfeeding in the LDR can also set the stage for sustained breastfeeding during hospitalization and for less supplementation with formula.

LDR vs. HDR brachytherapy for localized prostate cancer: the view from radiobiological models.

PubMed

King, Christopher R

2002-01-01

Permanent LDR brachytherapy and temporary HDR brachytherapy are competitive techniques for clinically localized prostate radiotherapy. Although a randomized trial will likely never be conducted comparing these two forms of brachytherapy, a comparative radiobiological modeling analysis proves useful in understanding some of their intrinsic differences, several of which could be exploited to improve outcomes. Radiobiological models based upon the linear quadratic equations are presented for fractionated external beam, fractionated (192)Ir HDR brachytherapy, and (125)I and (103)Pd LDR brachytherapy. These models incorporate the dose heterogeneities present in brachytherapy based upon patient-derived dose volume histograms (DVH) as well as tumor doubling times and repair kinetics. Radiobiological parameters are normalized to correspond to three accepted clinical risk factors based upon T-stage, PSA, and Gleason score to compare models with clinical series. Tumor control probabilities (TCP) for LDR and HDR brachytherapy (as monotherapy or combined with external beam) are compared with clinical bNED survival rates. Predictions are made for dose escalation with HDR brachytherapy regimens. Model predictions for dose escalation with external beam agree with clinical data and validate the models and their underlying assumptions. Both LDR and HDR brachytherapy achieve superior tumor control when compared with external beam at conventional doses (<70 Gy), but similar to results from dose escalation series. LDR brachytherapy as boost achieves superior tumor control than when used as monotherapy. Stage for stage, both LDR and current HDR regimens achieve similar tumor control rates, in agreement with current clinical data. HDR monotherapy with large-dose fraction sizes might achieve superior tumor control compared with LDR, especially if prostate cancer possesses a high sensitivity to dose fractionation (i.e., if the alpha/beta ratio is low). Radiobiological models support the

Urethral toxicity after LDR brachytherapy: experience in Japan.

PubMed

Tanaka, Nobumichi; Asakawa, Isao; Hasegawa, Masatoshi; Fujimoto, Kiyohide

2015-01-01

Urinary toxicity is common after low-dose-rate (LDR) brachytherapy, and the resolution of urinary toxicity is a concern. In particular, urinary frequency is the most common adverse event among the urinary toxicities. We have previously reported that approximately 70% of patients experience urinary frequency during the first 6 months after seed implantation. Most urinary adverse events were classified as Grade 1, and Grade 2 or higher adverse events were rare. The incidence of urinary retention was approximately 2-4%. A high International Prostate Symptom Score before seed implantation was an independent predictor of acute urinary toxicity of Grade 2 or higher. Several previous reports from the United States also supported this trend. In Japan, LDR brachytherapy was legally approved in 2003. A nationwide prospective cohort study entitled Japanese Prostate Cancer Outcome Study of Permanent Iodine-125 Seed Implantation was initiated in July 2005. It is an important issue to limit urinary toxicities in patients who undergo LDR brachytherapy. Copyright © 2015 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

Large Deployable Reflector (LDR) - A concept for an orbiting submillimeter-infrared telescope for the 1990s

NASA Technical Reports Server (NTRS)

Swanson, P. N.; Gulkis, S.; Kulper, T. B. H.; Kiya, M.

1983-01-01

The history and background of the Large Deployable Reflector (LDR) are reviewed. The results of the June 1982 Asilomar (CA) workshop are incorporated into the LDR science objectives and telescope concept. The areas where the LDR may have the greatest scientific impact are in the study of star formation and planetary systems in the own and nearby galaxies and in cosmological studies of the structure and evolution of the early universe. The observational requirements for these and other scientific studies give rise to a set of telescope functional requirements. These, in turn, are satisfied by an LDR configuration which is a Cassegrain design with a 20 m diameter, actively controlled, segmented, primary reflector, diffraction limited at a wavelength of 30 to 50 microns. Technical challenges in the LDR development include construction of high tolerance mirror segments, surface figure measurement, figure control, vibration control, pointing, cryogenics, and coherent detectors. Project status and future plans for the LDR are discussed.

License restrictions at Barnwell

DOE Office of Scientific and Technical Information (OSTI.GOV)

Autry, V.R.

1991-12-31

The State of South Carolina was delegated the authority by the US Nuclear Regulatory Commission to regulate the receipt, possession, use and disposal of radioactive material as an Agreement State. Since 1970, the state has been the principal regulatory authority for the Barnwell Low-Level Waste Disposal Facility operated by Chem-Nuclear Systems, Inc. The radioactive material license issued authorizing the receipt and disposal of low-level waste contains numerous restrictions to ensure environmental protection and compliance with shallow land disposal performance criteria. Low-level waste has evolved from minimally contaminated items to complex waste streams containing high concentrations of radionuclides and processing chemicalsmore » which necessitated these restrictions. Additionally, some waste with their specific radionuclides and concentration levels, many classified as low-level radioactive waste, are not appropriate for shallow land disposal unless additional precautions are taken. This paper will represent a number of these restrictions, the rationale for them, and how they are being dealt with at the Barnwell disposal facility.« less

The use of nomograms in LDR-HDR prostate brachytherapy.

PubMed

Pujades, Ma Carmen; Camacho, Cristina; Perez-Calatayud, Jose; Richart, José; Gimeno, Jose; Lliso, Françoise; Carmona, Vicente; Ballester, Facundo; Crispín, Vicente; Rodríguez, Silvia; Tormo, Alejandro

2011-09-01

The common use of nomograms in Low Dose Rate (LDR) permanent prostate brachytherapy (BT) allows to estimate the number of seeds required for an implant. Independent dosimetry verification is recommended for each clinical dosimetry in BT. Also, nomograms can be useful for dose calculation quality assurance and they could be adapted to High Dose Rate (HDR). This work sets nomograms for LDR and HDR prostate-BT implants, which are applied to three different institutions that use different implant techniques. Patients treated throughout 2010 till April 2011 were considered for this study. This example was chosen to be the representative of the latest implant techniques and to ensure consistency in the planning. A sufficient number of cases for both BT modalities, prescription dose and different work methodology (depending on the institution) were taken into account. The specific nomograms were built using the correlation between the prostate volume and some characteristic parameters of each BT modality, such as the source Air Kerma Strength, number of implanted seeds in LDR or total radiation time in HDR. For each institution and BT modality, nomograms normalized to the prescribed dose were obtained and fitted to a linear function. The parameters of the adjustment show a good agreement between data and the fitting. It should be noted that for each institution these linear function parameters are different, indicating that each centre should construct its own nomograms. Nomograms for LDR and HDR prostate brachytherapy are simple quality assurance tools, specific for each institution. Nevertheless, their use should be complementary to the necessary independent verification.

Biological equivalence between LDR and PDR in cervical cancer: multifactor analysis using the linear-quadratic model.

PubMed

Couto, José Guilherme; Bravo, Isabel; Pirraco, Rui

2011-09-01

The purpose of this work was the biological comparison between Low Dose Rate (LDR) and Pulsed Dose Rate (PDR) in cervical cancer regarding the discontinuation of the afterloading system used for the LDR treatments at our Institution since December 2009. In the first phase we studied the influence of the pulse dose and the pulse time in the biological equivalence between LDR and PDR treatments using the Linear Quadratic Model (LQM). In the second phase, the equivalent dose in 2 Gy/fraction (EQD(2)) for the tumor, rectum and bladder in treatments performed with both techniques was evaluated and statistically compared. All evaluated patients had stage IIB cervical cancer and were treated with External Beam Radiotherapy (EBRT) plus two Brachytherapy (BT) applications. Data were collected from 48 patients (26 patients treated with LDR and 22 patients with PDR). In the analyses of the influence of PDR parameters in the biological equivalence between LDR and PDR treatments (Phase 1), it was calculated that if the pulse dose in PDR was kept equal to the LDR dose rate, a small the-rapeutic loss was expected. If the pulse dose was decreased, the therapeutic window became larger, but a correction in the prescribed dose was necessary. In PDR schemes with 1 hour interval between pulses, the pulse time did not influence significantly the equivalent dose. In the comparison between the groups treated with LDR and PDR (Phase 2) we concluded that they were not equivalent, because in the PDR group the total EQD(2) for the tumor, rectum and bladder was smaller than in the LDR group; the LQM estimated that a correction in the prescribed dose of 6% to 10% was ne-cessary to avoid therapeutic loss. A correction in the prescribed dose was necessary; this correction should be achieved by calculating the PDR dose equivalent to the desired LDR total dose.

Phase III randomized trial comparing LDR and HDR brachytherapy in treatment of cervical carcinoma.

PubMed

Lertsanguansinchai, Prasert; Lertbutsayanukul, Chawalit; Shotelersuk, Kanjana; Khorprasert, Chonlakiet; Rojpornpradit, Prayuth; Chottetanaprasith, Taywin; Srisuthep, Apiradee; Suriyapee, Sivalee; Jumpangern, Chotika; Tresukosol, Damrong; Charoonsantikul, Chulee

2004-08-01

Intracavitary brachytherapy plays an important role in the treatment of cervical carcinoma. Previous results have shown controversy between the effect of dose rate on tumor control and the occurrence of complications. We performed a prospective randomized clinical trial to compare the clinical outcomes between low-dose-rate (LDR) and high-dose-rate (HDR) intracavitary brachytherapy for treatment of invasive uterine cervical carcinoma. A total of 237 patients with previously untreated invasive carcinoma of the uterine cervix treated at King Chulalongkorn Memorial Hospital were randomized between June 1995 and December 2001. Excluding ineligible, incomplete treatment, and incomplete data patients, 109 and 112 patients were in the LDR and HDR groups, respectively. All patients were treated with external beam radiotherapy and LDR or HDR intracavitary brachytherapy using the Chulalongkorn treatment schedule. The median follow-up for the LDR and HDR groups was 40.2 and 37.2 months, respectively. The actuarial 3-year overall and relapse-free survival rate for all patients was 69.6% and 70%, respectively. The 3-year overall survival rate in the LDR and HDR groups was 70.9% and 68.4% (p = 0.75) and the 3-year pelvic control rate was 89.1% and 86.4% (p = 0.51), respectively. The 3-year relapse-free survival rate in both groups was 69.9% (p = 0.35). Most recurrences were distant metastases, especially in Stage IIB and IIIB patients. Grade 3 and 4 complications were found in 2.8% and 7.1% of the LDR and HDR groups (p = 0.23). Comparable outcomes were demonstrated between LDR and HDR intracavitary brachytherapy. Concerning patient convenience, the lower number of medical personnel needed, and decreased radiation to health care workers, HDR intracavitary brachytherapy is an alternative to conventional LDR brachytherapy. The high number of distant failure suggests that other modalities such as systemic concurrent or adjuvant chemotherapy might lower this high recurrence

Rectourethral fistula following LDR brachytherapy.

PubMed

Borchers, Holger; Pinkawa, Michael; Donner, Andreas; Wolter, Timm P; Pallua, Norbert; Eble, Michael J; Jakse, Gerhard

2009-01-01

Modern LDR brachytherapy has drastically reduced rectal toxicity and decreased the occurrence of rectourethral fistulas to <0.5% of patients. Therefore, symptoms of late-onset sequelae are often ignored initially. These fistulas cause severe patient morbidity and require interdisciplinary treatment. We report on the occurrence and management of a rectourethral fistula which occurred 4 years after (125)I seed implantation. Copyright 2009 S. Karger AG, Basel.

The Large Deployable Reflector (LDR) - Plans and progress

NASA Technical Reports Server (NTRS)

Swanson, Paul N.

1987-01-01

The program history, scientific aims, design, and projected performance of the LDR, a 20-m-primary two-stage four-mirror orbiting sub-mm/FIR astronomical observatory under NASA development, are reviewed. It is shown that the LDR would provide capabilities complementary to those of IRAS, the Kuiper Airborne Observatory, the IRTF, the Hubble Space Telescope, and the planned Space IR Telescope Facility for observations of small-scale background anisotropies, high-redshift galaxies, and objects at temperatures of a few times 10 K or lower. The current design concept is illustrated with extensive drawings, diagrams, and tables of instrument parameters. Particular attention is given to the graphite-epoxy facing and Al-honeycomb core of the primary structure, the focal-plane instruments, and outstanding technological problems.

The use of nomograms in LDR-HDR prostate brachytherapy

PubMed Central

Camacho, Cristina; Perez-Calatayud, Jose; Richart, José; Gimeno, Jose; Lliso, Françoise; Carmona, Vicente; Ballester, Facundo; Crispín, Vicente; Rodríguez, Silvia; Tormo, Alejandro

2011-01-01

Purpose The common use of nomograms in Low Dose Rate (LDR) permanent prostate brachytherapy (BT) allows to estimate the number of seeds required for an implant. Independent dosimetry verification is recommended for each clinical dosimetry in BT. Also, nomograms can be useful for dose calculation quality assurance and they could be adapted to High Dose Rate (HDR). This work sets nomograms for LDR and HDR prostate-BT implants, which are applied to three different institutions that use different implant techniques. Material and methods Patients treated throughout 2010 till April 2011 were considered for this study. This example was chosen to be the representative of the latest implant techniques and to ensure consistency in the planning. A sufficient number of cases for both BT modalities, prescription dose and different work methodology (depending on the institution) were taken into account. The specific nomograms were built using the correlation between the prostate volume and some characteristic parameters of each BT modality, such as the source Air Kerma Strength, number of implanted seeds in LDR or total radiation time in HDR. Results For each institution and BT modality, nomograms normalized to the prescribed dose were obtained and fitted to a linear function. The parameters of the adjustment show a good agreement between data and the fitting. It should be noted that for each institution these linear function parameters are different, indicating that each centre should construct its own nomograms. Conclusions Nomograms for LDR and HDR prostate brachytherapy are simple quality assurance tools, specific for each institution. Nevertheless, their use should be complementary to the necessary independent verification. PMID:23346120

27 CFR 44.63 - Restrictions on disposal of tobacco products, and cigarette papers and tubes on vessels and...

Code of Federal Regulations, 2012 CFR

2012-04-01

... tobacco products, and cigarette papers and tubes on vessels and aircraft. 44.63 Section 44.63 Alcohol... (CONTINUED) TOBACCO EXPORTATION OF TOBACCO PRODUCTS AND CIGARETTE PAPERS AND TUBES, WITHOUT PAYMENT OF TAX, OR WITH DRAWBACK OF TAX General § 44.63 Restrictions on disposal of tobacco products, and cigarette...

Biological equivalence between LDR and PDR in cervical cancer: multifactor analysis using the linear-quadratic model

PubMed Central

Bravo, Isabel; Pirraco, Rui

2011-01-01

Purpose The purpose of this work was the biological comparison between Low Dose Rate (LDR) and Pulsed Dose Rate (PDR) in cervical cancer regarding the discontinuation of the afterloading system used for the LDR treatments at our Institution since December 2009. Material and methods In the first phase we studied the influence of the pulse dose and the pulse time in the biological equivalence between LDR and PDR treatments using the Linear Quadratic Model (LQM). In the second phase, the equivalent dose in 2 Gy/fraction (EQD2) for the tumor, rectum and bladder in treatments performed with both techniques was evaluated and statistically compared. All evaluated patients had stage IIB cervical cancer and were treated with External Beam Radiotherapy (EBRT) plus two Brachytherapy (BT) applications. Data were collected from 48 patients (26 patients treated with LDR and 22 patients with PDR). Results In the analyses of the influence of PDR parameters in the biological equivalence between LDR and PDR treatments (Phase 1), it was calculated that if the pulse dose in PDR was kept equal to the LDR dose rate, a small the-rapeutic loss was expected. If the pulse dose was decreased, the therapeutic window became larger, but a correction in the prescribed dose was necessary. In PDR schemes with 1 hour interval between pulses, the pulse time did not influence significantly the equivalent dose. In the comparison between the groups treated with LDR and PDR (Phase 2) we concluded that they were not equivalent, because in the PDR group the total EQD2 for the tumor, rectum and bladder was smaller than in the LDR group; the LQM estimated that a correction in the prescribed dose of 6% to 10% was ne-cessary to avoid therapeutic loss. Conclusions A correction in the prescribed dose was necessary; this correction should be achieved by calculating the PDR dose equivalent to the desired LDR total dose. PMID:23346123

Non-Destructive Evaluation of Kissing Bonds using Local Defect Resonance (LDR) Spectroscopy: A Simulation Study

NASA Astrophysics Data System (ADS)

Delrue, S.; Tabatabaeipour, M.; Hettler, J.; Van Den Abeele, K.

With the growing demand from industry to optimize and further develop existing Non-Destructive Testing & Evaluation (NDT&E) techniques or new methods to detect and characterize incipient damage with high sensitivity and increased quality, ample efforts have been devoted to better understand the typical behavior of kissing bonds, such as delaminations and cracks. Recently, it has been shown experimentally that the nonlinear ultrasonic response of kissing bonds could be enhanced by using Local Defect Resonance (LDR) spectroscopy. LDR spectroscopy is an efficient NDT technique that takes advantage of the characteristic fre- quencies of the defect (defect resonances) in order to provide maximum acoustic wave-defect interaction. In fact, for nonlinear methodologies, the ultrasonic excitation of the sample should occur at either multiples or integer ratios of the characteristic defect resonance frequencies, in order to obtain the highest signal-to-noise response in the nonlinear LDR spectroscopy. In this paper, the potential of using LDR spectroscopy for the detection, localization and characterization of kissing bonds is illustrated using a 3D simulation code for elastic wave propagation in materials containing closed but dynamically active cracks or delaminations. Using the model, we are able to define an appropriate method, based on the Scaling Subtraction Method (SSM), to determine the local defect resonance frequencies of a delamination in a composite plate and to illustrate an increase in defect nonlinearity due to LDR. The simulation results will help us to obtain a better understanding of the concept of LDR and to assist in the further design and testing of LDR spectroscopy for the detection, localization and characterization of kissing bonds.

Local defect resonance (LDR): A route to highly efficient thermosonic and nonlinear ultrasonic NDT

NASA Astrophysics Data System (ADS)

Solodov, Igor

2014-02-01

The concept of LDR is based on the fact that inclusion of a defect leads to a local drop of rigidity for a certain mass of the material that should manifest in a particular characteristic frequency of the defect. A frequency match between the driving ultrasonic wave and this characteristic frequency provides an efficient energy pumping from the wave directly into the defect. For simulated and realistic defects in various materials the LDR-induced local resonance increase in the vibration amplitude averages up to ˜ (20-40 dB). Due to a strong resonance amplification of the local vibrations, the LDR-driven defects manifest a profound nonlinearity even at moderate ultrasonic excitation level. The nonlinearity combined with resonance results in efficient generation of the higher harmonics and is also used as a filter/amplifier in the frequency mixing mode of nonlinear NDT. The LDR high-Q thermal response enables to realize a frequency-selective imaging with an opportunity to distinguish between different defects by changing the driving frequency. The LDR-thermosonics requires much lower acoustic power to activate defects that makes it possible to avoid high-power ultrasonic instrumentation and proceed to a noncontact ultrasonic thermography by using air-coupled ultrasonic excitation.

Large Deployable Reflector (LDR) system concept and technology definition study. Volume 2: Technology assessment and technology development plan

NASA Technical Reports Server (NTRS)

Agnew, Donald L.; Jones, Peter A.

1989-01-01

A study was conducted to define reasonable and representative LDR system concepts for the purpose of defining a technology development program aimed at providing the requisite technological capability necessary to start LDR development by the end of 1991. This volume presents thirteen technology assessments and technology development plans, as well as an overview and summary of the LDR concepts. Twenty-two proposed augmentation projects are described (selected from more than 30 candidates). The five LDR technology areas most in need of supplementary support are: cryogenic cooling; astronaut assembly of the optically precise LDR in space; active segmented primary mirror; dynamic structural control; and primary mirror contamination control. Three broad, time-phased, five-year programs were synthesized from the 22 projects, scheduled, and funding requirements estimated.

Proposed Site Treatment Plan (PSTP). Volumes 1 and 2 and Reference Document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Helmich, E.; Noller, D.K.; Wierzbicki, K.S.

1994-12-22

The Compliance Plan Volume provides overall schedules with target dates for achieving compliance with the land disposal restrictions (LDR) and contains procedures to establish milestones to be enforced under the Order. Information regarding the technical evaluation of treatment options for SRS mixed wastes is contained in the Background Volume and is provided for informational purposes only.

Multiple scattering effects on the Linear Depolarization Ratio (LDR) measured during CaPE by a Ka-band air-borne radar

NASA Technical Reports Server (NTRS)

Iguchi, Toshio; Meneghini, Robert

1993-01-01

Air-borne radar measurements of thunderstorms were made as part of the CaPE (Convection and Precipitation/Electrification) experiment in Florida in July 1991. The radar has two channels, X-band (10 GHz) and Ka-band (34.5 GHz), and is capable of measuring cross-polarized returns as well as co-polarized returns. In stratiform rain, the cross-polarized components can be observed only at the bright band region and from the surface reflection. The linear depolarization ratios (LDR's) measured at X-band and Ka-band at the bright band are nearly equal. In convective rain, however, the LDR in Ka-band often exceeds the X-band LDR by several dB, and sometimes by more than 10 dB, reaching LDR values of up to -5 dB over heavy convective rain. For randomly oriented hydrometeors, such high LDR values cannot be explained by single scattering from non-spherical scattering particles alone. Because the LDR by single backscatter depends weakly on the wavelength, the difference between the Ka-band and X-band LDR's suggests that multiple scattering effects prevail in the Ka-band LDR. In order to test this inference, the magnitude of the cross-polarized component created by double scattering was calculated using the parameters of the airborne radar, which for both frequencies has beamwidths of 5.1 degrees and pulse widths of 0.5 microsecond. Uniform rain beyond the range of 3 km is assumed.

25 CFR 15.3 - Who can make a will disposing of trust or restricted land or trust personalty?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Who can make a will disposing of trust or restricted land or trust personalty? 15.3 Section 15.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROBATE PROBATE OF INDIAN ESTATES, EXCEPT FOR MEMBERS OF THE OSAGE NATION AND THE FIVE CIVILIZED TRIBES Introduction § 15.3 Who can make a will...

Emesis as a Screening Diagnostic for Low Dose Rate (LDR) Total Body Radiation Exposure.

PubMed

Camarata, Andrew S; Switchenko, Jeffrey M; Demidenko, Eugene; Flood, Ann B; Swartz, Harold M; Ali, Arif N

2016-04-01

Current radiation disaster manuals list the time-to-emesis (TE) as the key triage indicator of radiation dose. The data used to support TE recommendations were derived primarily from nearly instantaneous, high dose-rate exposures as part of variable condition accident databases. To date, there has not been a systematic differentiation between triage dose estimates associated with high and low dose rate (LDR) exposures, even though it is likely that after a nuclear detonation or radiologic disaster, many surviving casualties would have received a significant portion of their total exposure from fallout (LDR exposure) rather than from the initial nuclear detonation or criticality event (high dose rate exposure). This commentary discusses the issues surrounding the use of emesis as a screening diagnostic for radiation dose after LDR exposure. As part of this discussion, previously published clinical data on emesis after LDR total body irradiation (TBI) is statistically re-analyzed as an illustration of the complexity of the issue and confounding factors. This previously published data includes 107 patients who underwent TBI up to 10.5 Gy in a single fraction delivered over several hours at 0.02 to 0.04 Gy min. Estimates based on these data for the sensitivity of emesis as a screening diagnostic for the low dose rate radiation exposure range from 57.1% to 76.6%, and the estimates for specificity range from 87.5% to 99.4%. Though the original data contain multiple confounding factors, the evidence regarding sensitivity suggests that emesis appears to be quite poor as a medical screening diagnostic for LDR exposures.

Characterization of Ze and LDR of nonspherical and inhomogeneous ice particles for 95-GHz cloud radar: Its implication to microphysical retrievals

NASA Astrophysics Data System (ADS)

Sato, Kaori; Okamoto, Hajime

2006-11-01

Effect of density, shape, and orientation on radar reflectivity factor (Ze) and linear depolarization ratio (LDR) at 95 GHz are investigated by using the discrete dipole approximation (DDA) for ice cloud studies. We consider hexagonal plate, hollow hexagonal column, and hollow bullet rosette in horizontal (2-D) or three-dimensional (3-D) random orientation. We first validate a widely used method to take into account the density and shape effects by the combinational use of Mie theory with the Maxwell-Garnett mixing rule (the MG-Mie method). It is found that the MG-Mie method underestimates Ze and its applicability is limited to sizes smaller than 40 μm. On the basis of the DDA, it is possible to separately treat density, aspect ratio, orientation, and shape. Effect of density turns out to be minor. Orientation and shape are the major controlling factors for Ze especially at effective radius reff > 100 μm and LDR except for very large sizes where the effect of orientation in LDR diminishes. Comparison between the DDA results and the analytical solution for 3-D Rayleigh spheroids show that LDR in the small size range is characterized by the target boundary and aspect ratio. In the large size range, LDR reveals features of a single target element; for example, LDR of bullet rosette is similar to that of a single branch of the particle. Combinational use of Ze and LDR is effective in microphysics retrieval for LDR < -23 dB. For LDR > -23 dB, additional information such as Doppler velocity is required.

Wavefront error sensing for LDR

NASA Technical Reports Server (NTRS)

Tubbs, Eldred F.; Glavich, T. A.

1988-01-01

Wavefront sensing is a significant aspect of the LDR control problem and requires attention at an early stage of the control system definition and design. A combination of a Hartmann test for wavefront slope measurement and an interference test for piston errors of the segments was examined and is presented as a point of departure for further discussion. The assumption is made that the wavefront sensor will be used for initial alignment and periodic alignment checks but that it will not be used during scientific observations. The Hartmann test and the interferometric test are briefly examined.

Transition from LDR to HDR brachytherapy for cervical cancer: Evaluation of tumor control, survival, and toxicity.

PubMed

Romano, K D; Pugh, K J; Trifiletti, D M; Libby, B; Showalter, T N

In 2012, our institution transitioned from low-dose-rate (LDR) brachytherapy to high dose-rate (HDR) brachytherapy. We report clinical outcomes after brachytherapy for cervical cancer at our institution over a continuous 10-year period. From 2004 to 2014, 258 women (184 LDR and 74 HDR) were treated with tandem and ovoid brachytherapy in the multidisciplinary management of International Federation of Gynecology and Obstetrics Stages IA-IVB cervical cancer. Clinical and treatment-related prognostic factors including age, stage, smoking status, relevant doses, and toxicity data were recorded. Median followup for the LDR and HDR groups was 46 months and 12 months, respectively. The majority of patients (92%) received external beam radiotherapy as well as concurrent chemotherapy (83%) before the start of brachytherapy. For all stages, the 1-year local control and overall survival (OS) rates were comparable between the LDR and HDR groups (87% vs. 81%, p = 0.12; and 75% vs. 85%, p = 0.16), respectively. Factors associated with OS on multivariate analysis include age, stage, and nodal involvement. On multivariate analysis, severe toxicity (acute or chronic) was higher with HDR than LDR (24% vs. 10%, p = 0.04). Additional prognostic factors associated with increased severe toxicity include former/current smokers and total dose to lymph nodes. This comparative retrospective analysis of a large cohort of women treated with brachytherapy demonstrates no significant difference in OS or local control between the LDR and HDR. Acute and chronic toxicity increased shortly after the implementation of HDR, highlighting the importance of continued refinement of HDR methods, including integrating advanced imaging. Copyright © 2016 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

Time to PSA rise differentiates the PSA bounce after HDR and LDR brachytherapy of prostate cancer

PubMed Central

Skowronek, Janusz

2018-01-01

Purpose To investigate the differences in prostate-specific antigen (PSA) bounce (PB) after high-dose-rate (HDR-BT) or low-dose-rate (LDR-BT) brachytherapy alone in prostate cancer patients. Materials and methods Ninety-four patients with localized prostate cancer (T1-T2cN0), age ranged 50-81 years, were treated with brachytherapy alone between 2008 and 2010. Patients were diagnosed with adenocarcinoma, Gleason score ≤ 7. The LDR-BT total dose was 144-145 Gy, in HDR-BT – 3 fractions of 10.5 or 15 Gy. The initial PSA level (iPSA) was assessed before treatment, then PSA was rated every 3 months over the first 2 years, and every 6 months during the next 3 years. Median follow-up was 3.0 years. Results Mean iPSA was 7.8 ng/ml. In 58 cases, PSA decreased gradually without PB or biochemical failure (BF). In 24% of patients, PB was observed. In 23 cases (24%), PB was observed using 0.2 ng/ml definition; in 10 cases (11%), BF was diagnosed using nadir + 2 ng/ml definition. The HDR-BT and LDR-BT techniques were not associated with higher level of PB (26 vs. 22%, p = 0.497). Time to the first PSA rise finished with PB was significantly shorter after HDR-BT then after LDR-BT (median, 10.5 vs. 18.0 months) during follow-up. Predictors for PB were observed only after HDR-BT. Androgen deprivation therapy (ADT) and higher Gleason score decreased the risk of PB (HR = 0.11, p = 0.03; HR = 0.51, p = 0.01). The higher PSA nadir and longer time to PSA nadir increased the risk of PB (HR 3.46, p = 0.02; HR 1.04, p = 0.04). There was no predictors for PB after LDR-BT. Conclusions HDR-BT and LDR-BT for low and intermediate risk prostate cancer had similar PB rate. The PB occurred earlier after HDR-BT than after LDR-BT. ADT and higher Gleason score decreased, and higher PSA nadir and longer time to PSA nadir increased the risk of PB after HDR-BT. PMID:29619050

Time to PSA rise differentiates the PSA bounce after HDR and LDR brachytherapy of prostate cancer.

PubMed

Burchardt, Wojciech; Skowronek, Janusz

2018-02-01

To investigate the differences in prostate-specific antigen (PSA) bounce (PB) after high-dose-rate (HDR-BT) or low-dose-rate (LDR-BT) brachytherapy alone in prostate cancer patients. Ninety-four patients with localized prostate cancer (T1-T2cN0), age ranged 50-81 years, were treated with brachytherapy alone between 2008 and 2010. Patients were diagnosed with adenocarcinoma, Gleason score ≤ 7. The LDR-BT total dose was 144-145 Gy, in HDR-BT - 3 fractions of 10.5 or 15 Gy. The initial PSA level (iPSA) was assessed before treatment, then PSA was rated every 3 months over the first 2 years, and every 6 months during the next 3 years. Median follow-up was 3.0 years. Mean iPSA was 7.8 ng/ml. In 58 cases, PSA decreased gradually without PB or biochemical failure (BF). In 24% of patients, PB was observed. In 23 cases (24%), PB was observed using 0.2 ng/ml definition; in 10 cases (11%), BF was diagnosed using nadir + 2 ng/ml definition. The HDR-BT and LDR-BT techniques were not associated with higher level of PB (26 vs. 22%, p = 0.497). Time to the first PSA rise finished with PB was significantly shorter after HDR-BT then after LDR-BT (median, 10.5 vs. 18.0 months) during follow-up. Predictors for PB were observed only after HDR-BT. Androgen deprivation therapy (ADT) and higher Gleason score decreased the risk of PB (HR = 0.11, p = 0.03; HR = 0.51, p = 0.01). The higher PSA nadir and longer time to PSA nadir increased the risk of PB (HR 3.46, p = 0.02; HR 1.04, p = 0.04). There was no predictors for PB after LDR-BT. HDR-BT and LDR-BT for low and intermediate risk prostate cancer had similar PB rate. The PB occurred earlier after HDR-BT than after LDR-BT. ADT and higher Gleason score decreased, and higher PSA nadir and longer time to PSA nadir increased the risk of PB after HDR-BT.

Additive protection by LDR and FGF21 treatment against diabetic nephropathy in type 2 diabetes model.

PubMed

Shao, Minglong; Yu, Lechu; Zhang, Fangfang; Lu, Xuemian; Li, Xiaokun; Cheng, Peng; Lin, Xiufei; He, Luqing; Jin, Shunzi; Tan, Yi; Yang, Hong; Zhang, Chi; Cai, Lu

2015-07-01

The onset of diabetic nephropathy (DN) is associated with both systemic and renal changes. Fibroblast growth factor (FGF)-21 prevents diabetic complications mainly by improving systemic metabolism. In addition, low-dose radiation (LDR) protects mice from DN directly by preventing renal oxidative stress and inflammation. In the present study, we tried to define whether the combination of FGF21 and LDR could further prevent DN by blocking its systemic and renal pathogeneses. To this end, type 2 diabetes was induced by feeding a high-fat diet for 12 wk followed by a single dose injection of streptozotocin. Diabetic mice were exposed to 50 mGy LDR every other day for 4 wk with and without 1.5 mg/kg FGF21 daily for 8 wk. The changes in systemic parameters, including blood glucose levels, lipid profiles, and insulin resistance, as well as renal pathology, were examined. Diabetic mice exhibited renal dysfunction and pathological abnormalities, all of which were prevented significantly by LDR and/or FGF21; the best effects were observed in the group that received the combination treatment. Our studies revealed that the additive renal protection conferred by the combined treatment against diabetes-induced renal fibrosis, inflammation, and oxidative damage was associated with the systemic improvement of hyperglycemia, hyperlipidemia, and insulin resistance. These results suggest that the combination treatment with LDR and FGF21 prevented DN more efficiently than did either treatment alone. The mechanism behind these protective effects could be attributed to the suppression of both systemic and renal pathways. Copyright © 2015 the American Physiological Society.

Additive protection by LDR and FGF21 treatment against diabetic nephropathy in type 2 diabetes model

PubMed Central

Shao, Minglong; Yu, Lechu; Zhang, Fangfang; Lu, Xuemian; Li, Xiaokun; Cheng, Peng; Lin, Xiufei; He, Luqing; Jin, Shunzi; Tan, Yi; Yang, Hong; Cai, Lu

2015-01-01

The onset of diabetic nephropathy (DN) is associated with both systemic and renal changes. Fibroblast growth factor (FGF)-21 prevents diabetic complications mainly by improving systemic metabolism. In addition, low-dose radiation (LDR) protects mice from DN directly by preventing renal oxidative stress and inflammation. In the present study, we tried to define whether the combination of FGF21 and LDR could further prevent DN by blocking its systemic and renal pathogeneses. To this end, type 2 diabetes was induced by feeding a high-fat diet for 12 wk followed by a single dose injection of streptozotocin. Diabetic mice were exposed to 50 mGy LDR every other day for 4 wk with and without 1.5 mg/kg FGF21 daily for 8 wk. The changes in systemic parameters, including blood glucose levels, lipid profiles, and insulin resistance, as well as renal pathology, were examined. Diabetic mice exhibited renal dysfunction and pathological abnormalities, all of which were prevented significantly by LDR and/or FGF21; the best effects were observed in the group that received the combination treatment. Our studies revealed that the additive renal protection conferred by the combined treatment against diabetes-induced renal fibrosis, inflammation, and oxidative damage was associated with the systemic improvement of hyperglycemia, hyperlipidemia, and insulin resistance. These results suggest that the combination treatment with LDR and FGF21 prevented DN more efficiently than did either treatment alone. The mechanism behind these protective effects could be attributed to the suppression of both systemic and renal pathways. PMID:25968574

Molecular characterization of long direct repeat (LDR) sequences expressing a stable mRNA encoding for a 35-amino-acid cell-killing peptide and a cis-encoded small antisense RNA in Escherichia coli.

PubMed

Kawano, Mitsuoki; Oshima, Taku; Kasai, Hiroaki; Mori, Hirotada

2002-07-01

Genome sequence analyses of Escherichia coli K-12 revealed four copies of long repetitive elements. These sequences are designated as long direct repeat (LDR) sequences. Three of the repeats (LDR-A, -B, -C), each approximately 500 bp in length, are located as tandem repeats at 27.4 min on the genetic map. Another copy (LDR-D), 450 bp in length and nearly identical to LDR-A, -B and -C, is located at 79.7 min, a position that is directly opposite the position of LDR-A, -B and -C. In this study, we demonstrate that LDR-D encodes a 35-amino-acid peptide, LdrD, the overexpression of which causes rapid cell killing and nucleoid condensation of the host cell. Northern blot and primer extension analysis showed constitutive transcription of a stable mRNA (approximately 370 nucleotides) encoding LdrD and an unstable cis-encoded antisense RNA (approximately 60 nucleotides), which functions as a trans-acting regulator of ldrD translation. We propose that LDR encodes a toxin-antitoxin module. LDR-homologous sequences are not pre-sent on any known plasmids but are conserved in Salmonella and other enterobacterial species.

7 CFR 319.75 - Restrictions on importation of restricted articles; disposal of articles refused importation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... FOREIGN QUARANTINE NOTICES Khapra Beetle § 319.75 Restrictions on importation of restricted articles... entry into the United States of khapra beetle (Trogoderma granarium Everts) it is necessary to restrict...

7 CFR 319.75 - Restrictions on importation of restricted articles; disposal of articles refused importation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... FOREIGN QUARANTINE NOTICES Khapra Beetle § 319.75 Restrictions on importation of restricted articles... entry into the United States of khapra beetle (Trogoderma granarium Everts) it is necessary to restrict...

7 CFR 319.75 - Restrictions on importation of restricted articles; disposal of articles refused importation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... FOREIGN QUARANTINE NOTICES Khapra Beetle § 319.75 Restrictions on importation of restricted articles... entry into the United States of khapra beetle (Trogoderma granarium Everts) it is necessary to restrict...

Is there any place for LDR brachytherapy for head and neck carcinomas in HDR era?

PubMed

Fijuth, Jacek

2009-03-01

In Poland, the classical LDR brachytherapy for head and neck carcinomas with Ir-192 wires or hairpins has completely disappeared some time ago after 30 years of successful clinical use. Can this technique be fully and safely replaced by HDR or PDR application? This option seems attractive because of new possibilities of 3D reconstruction and computer real-time treatment planning and optimization. However, in my opinion, long time is needed to get a clinical and scientific experience that has been accumulated for decades with the use of LDR technique.

Large Deployable Reflector (LDR) system concept and technology definition study. Volume 1: Executive summary, analyses and trades, and system concepts

NASA Technical Reports Server (NTRS)

Agnew, Donald L.; Jones, Peter A.

1989-01-01

A study was conducted to define reasonable and representative large deployable reflector (LDR) system concepts for the purpose of defining a technology development program aimed at providing the requisite technological capability necessary to start LDR development by the end of 1991. This volume includes the executive summary for the total study, a report of thirteen system analysis and trades tasks (optical configuration, aperture size, reflector material, segmented mirror, optical subsystem, thermal, pointing and control, transportation to orbit, structures, contamination control, orbital parameters, orbital environment, and spacecraft functions), and descriptions of three selected LDR system concepts. Supporting information is contained in appendices.

Serial processing of biological reactions using flow-through microfluidic devices: coupled PCR/LDR for the detection of low-abundant DNA point mutations.

PubMed

Hashimoto, Masahiko; Barany, Francis; Xu, Feng; Soper, Steven A

2007-09-01

We have fabricated a flow-through biochip consisting of passive elements for the analysis of single base mutations in genomic DNA using polycarbonate (PC) as the substrate. The biochip was configured to carry out two processing steps on the input sample, a primary polymerase chain reaction (PCR) followed by an allele-specific ligation detection reaction (LDR) for scoring the presence of low abundant point mutations in genomic DNA. The operation of the device was demonstrated by detecting single nucleotide polymorphisms in gene fragments (K-ras) that carry high diagnostic value for colorectal cancers. The effect of carryover from the primary PCR on the subsequent LDR was investigated in terms of LDR yield and fidelity. We found that a post-PCR treatment step prior to the LDR phase of the assay was not essential. As a consequence, a thermal cycling microchip was used for a sequential PCR/LDR in a simple continuous-flow format, in which the following three steps were carried out: (1) exponential amplification of the gene fragments from genomic DNA; (2) mixing of the resultant PCR product(s) with an LDR cocktail via a Y-shaped passive micromixer; and (3) ligation of two primers (discriminating primer that carried the complement base to the mutation locus being interrogated and a common primer) only when the particular mutation was present in the genomic DNA. We successfully demonstrated the ability to detect one mutant DNA in 1000 normal sequences with the integrated microfluidic system. The PCR/LDR assay using the microchip performed the entire assay at a relatively fast processing speed: 18.7 min for 30 rounds of PCR, 4.1 min for 13 rounds of LDR (total processing time = ca. 22.8 min) and could screen multiple mutations simultaneously in a multiplexed format. In addition, the low cost of the biochip due to the fact that it was fabricated from polymers using replication technologies and consisted of passive elements makes the platform amenable to clinical diagnostics

5 CFR 582.401 - Aggregate disposable earnings.

Code of Federal Regulations, 2010 CFR

2010-01-01

... COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Consumer Credit Protection Act Restrictions § 582.401 Aggregate disposable earnings. In accordance with the Consumer Credit Protection Act, the aggregate disposable earnings under this part are the employee-obligor's pay less those amounts excluded in accordance...

Differential cellular responses to prolonged LDR-IR in MLH1-proficient and MLH1-deficient colorectal cancer HCT116 cells.

PubMed

Yan, Tao; Seo, Yuji; Kinsella, Timothy J

2009-11-15

MLH1 is a key DNA mismatch repair (MMR) protein involved in maintaining genomic stability by participating in the repair of endogenous and exogenous mispairs in the daughter strands during S phase. Exogenous mispairs can result following treatment with several classes of chemotherapeutic drugs, as well as with ionizing radiation. In this study, we investigated the role of the MLH1 protein in determining the cellular and molecular responses to prolonged low-dose rate ionizing radiation (LDR-IR), which is similar to the clinical use of cancer brachytherapy. An isogenic pair of MMR(+) (MLH1(+)) and MMR(-) (MLH1(-)) human colorectal cancer HCT116 cells was exposed to prolonged LDR-IR (1.3-17 cGy/h x 24-96 h). The clonogenic survival and gene mutation rates were examined. Cell cycle distribution was analyzed with flow cytometry. Changes in selected DNA damage repair proteins, DNA damage response proteins, and cell death marker proteins were examined with Western blotting. MLH1(+) HCT116 cells showed greater radiosensitivity with enhanced expression of apoptotic and autophagic markers, a reduced HPRT gene mutation rate, and more pronounced cell cycle alterations (increased late-S population and a G(2)/M arrest) following LDR-IR compared with MLH1(-) HCT116 cells. Importantly, a progressive increase in MLH1 protein levels was found in MLH1(+) cells during prolonged LDR-IR, which was temporally correlated with a progressive decrease in Rad51 protein (involved in homologous recombination) levels. MLH1 status significantly affects cellular responses to prolonged LDR-IR. MLH1 may enhance cell radiosensitivity to prolonged LDR-IR through inhibition of homologous recombination (through inhibition of Rad51).

State-of-the-art: prostate LDR brachytherapy.

PubMed

Voulgaris, S; Nobes, J P; Laing, R W; Langley, S E M

2008-01-01

This article on low dose rate (LDR) prostate brachytherapy reviews long-term results, patient selection and quality of life issues. Mature results from the United States and United Kingdom are reported and issues regarding definitions of biochemical failure are discussed. Latest data comparing brachytherapy with radical prostatectomy or no definitive treatment and also the risk of secondary malignancies after prostate brachytherapy are presented. Urological parameters of patient selection and quality of life issues concerning urinary, sexual and bowel function are reviewed. The position of prostate brachytherapy next to surgery as a first-line treatment modality is demonstrated.

Disposal of Chemotherapeutic Agent -- Contaminated Waste

DTIC Science & Technology

1989-03-01

RESTRICTIVE MARKINGS 2a SECURITY CLASSIFICATION AUTHORITY 3 . DISTRIBUTION/AVAILABILITY OF REPORT 2b. DECLASSIFICATION/DOWNGRADING SCHEDULE Approved for Public...AIR .............. 22 INCINERATION SYSTEM 2 CHEMOTHERAPEUTIC WASTE THERMAL ...... 32 DESTRUCTION DISPOSAL SYSTEM 3 FRONT VIEW OF INCINERATION...The Environmental Protection Agency has published a manual (Reference 1) which provides guidelines on handling and 3 disposal of infectious waste from

Comparative quantification of human intestinal bacteria based on cPCR and LDR/LCR

PubMed Central

Tang, Zhou-Rui; Li, Kai; Zhou, Yu-Xun; Xiao, Zhen-Xian; Xiao, Jun-Hua; Huang, Rui; Gu, Guo-Hao

2012-01-01

AIM: To establish a multiple detection method based on comparative polymerase chain reaction (cPCR) and ligase detection reaction (LDR)/ligase chain reaction (LCR) to quantify the intestinal bacterial components. METHODS: Comparative quantification of 16S rDNAs from different intestinal bacterial components was used to quantify multiple intestinal bacteria. The 16S rDNAs of different bacteria were amplified simultaneously by cPCR. The LDR/LCR was examined to actualize the genotyping and quantification. Two beneficial (Bifidobacterium, Lactobacillus) and three conditionally pathogenic bacteria (Enterococcus, Enterobacterium and Eubacterium) were used in this detection. With cloned standard bacterial 16S rDNAs, standard curves were prepared to validate the quantitative relations between the ratio of original concentrations of two templates and the ratio of the fluorescence signals of their final ligation products. The internal controls were added to monitor the whole detection flow. The quantity ratio between two bacteria was tested. RESULTS: cPCR and LDR revealed obvious linear correlations with standard DNAs, but cPCR and LCR did not. In the sample test, the distributions of the quantity ratio between each two bacterial species were obtained. There were significant differences among these distributions in the total samples. But these distributions of quantity ratio of each two bacteria remained stable among groups divided by age or sex. CONCLUSION: The detection method in this study can be used to conduct multiple intestinal bacteria genotyping and quantification, and to monitor the human intestinal health status as well. PMID:22294830

Comparative quantification of human intestinal bacteria based on cPCR and LDR/LCR.

PubMed

Tang, Zhou-Rui; Li, Kai; Zhou, Yu-Xun; Xiao, Zhen-Xian; Xiao, Jun-Hua; Huang, Rui; Gu, Guo-Hao

2012-01-21

To establish a multiple detection method based on comparative polymerase chain reaction (cPCR) and ligase detection reaction (LDR)/ligase chain reaction (LCR) to quantify the intestinal bacterial components. Comparative quantification of 16S rDNAs from different intestinal bacterial components was used to quantify multiple intestinal bacteria. The 16S rDNAs of different bacteria were amplified simultaneously by cPCR. The LDR/LCR was examined to actualize the genotyping and quantification. Two beneficial (Bifidobacterium, Lactobacillus) and three conditionally pathogenic bacteria (Enterococcus, Enterobacterium and Eubacterium) were used in this detection. With cloned standard bacterial 16S rDNAs, standard curves were prepared to validate the quantitative relations between the ratio of original concentrations of two templates and the ratio of the fluorescence signals of their final ligation products. The internal controls were added to monitor the whole detection flow. The quantity ratio between two bacteria was tested. cPCR and LDR revealed obvious linear correlations with standard DNAs, but cPCR and LCR did not. In the sample test, the distributions of the quantity ratio between each two bacterial species were obtained. There were significant differences among these distributions in the total samples. But these distributions of quantity ratio of each two bacteria remained stable among groups divided by age or sex. The detection method in this study can be used to conduct multiple intestinal bacteria genotyping and quantification, and to monitor the human intestinal health status as well.

LDR reverses DDP resistance in ovarian cancer cells by affecting ERCC-1, Bcl-2, Survivin and Caspase-3 expressions.

PubMed

Ju, Xingyan; Yu, Hongsheng; Liang, Donghai; Jiang, Tao; Liu, Yuanwei; Chen, Ling; Dong, Qing; Liu, Xiaoran

2018-06-01

Ovarian cancer is the most frequent cause of death resulting from malignant gynecological tumors. After surgical intervention, cisplatin (DDP) is a major chemotherapy drug for ovarian cancer, but the ovarian cancer cells tend to develop DDP resistance in the clinical setting. Tumor cells are sensitive to low-dose radiation (LDR). However, how the LDR therapy improves the effects of chemotherapy drugs on ovarian cancer is not well understood. This study aimed to explore this issue. The SKOV3/DDP cells were divided into 3 groups, including low-dose group, conventional-dose group, and control group (no radiation). Cell counting kit-8 assay was performed to measure cell proliferation. Flow cytometric analysis was then utilized to quantify the apoptosis with classical Annexin V/propidium iodide co-staining. And Real-time quantitative PCR and western blot were eventually used to analyze the mRNA and protein levels of excision repair cross complementing-group 1 (ERCC1), B-cell lymphoma 2 (Bcl-2), Survivin and Caspase-3, respectively. The IC50 value of DDP in the low-dose group was significantly lower compared with the other two groups. Compared with the conventional-dose group and control group, LDR treatment resulted in significantly more apoptosis. Besides, LDR treatment significantly decreased the mRNA and protein expression of ERCC1, Bcl-2, and Survivin, and enhanced the mRNA and protein expression of Caspase-3 compared with the other two groups. LDR reversed DDP resistance in SKOV3/DDP cells possibly by suppressing ERCC1, Bcl-2, and Survivin expressions, and increasing Caspase-3 expression. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

7 CFR 352.10 - Inspection; safeguards; disposal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... facilities for immediate exportation. (x) Any other related factor which should be considered, such as intent...; safeguards; disposal. (a) Inspection and release. Prohibited and restricted products and articles subject to... restricted products and articles under this part shall be subject to such safeguards as may be prescribed in...

Comparative study of LDR (Manchester system) and HDR image-guided conformal brachytherapy of cervical cancer: patterns of failure, late complications, and survival.

PubMed

Narayan, Kailash; van Dyk, Sylvia; Bernshaw, David; Rajasooriyar, Chrishanthi; Kondalsamy-Chennakesavan, Srinivas

2009-08-01

To compare patterns of failure, late toxicities, and survival in locally advanced cervical cancer patients treated by either low-dose-rate (LDR) or conformal high-dose-rate (HDRc) brachytherapy as a part of curative radiotherapy. A retrospective comparative study of 217 advanced cervix cancer patients was conducted; 90 of these patients received LDR and 127 received HDRc brachytherapy. All patients were staged using International Federation of Gynecology and Obstetrics (FIGO) rules, had pretreatment magnetic resonance imaging (MRI), and were treated with concurrent cisplatin chemoradiotherapy. Both groups matched for FIGO stage, MRI tumor volume, and uterine invasion status. Local and pelvic failures were similar 12-13% and 14% both in both groups. Abdominal and systemic failures in LDR group were 21% and 24%, whereas corresponding failures in HDRc group were 20% and 24%. Sixty-eight percent (87/127) of patients treated by HDRc remained asymptomatic, whereas 42% (38/90) of patients were asymptomatic from the bowel and bladder symptoms after treatment with LDR. The 5-year OS rate was 60% (SE = 4%). The 5-year failure-free survival rate was 55% (SE = 3%). There was no significant difference between the groups. Image-guided HDRc planning led to a large decrease in late radiation effects in patients treated by HDRc. Patterns of failure and survival were similar in patients treated either by LDR or HDRc.

40 CFR Appendix Vii to Part 268 - LDR Effective Dates of Surface Disposed Prohibited Hazardous Wastes

Code of Federal Regulations, 2012 CFR

2012-07-01

... Dates of Surface Disposed Wastes (Non-Soil and Debris) Regulated in the LDRS a—Comprehensive List Waste... radioactive wastes June 30, 1994. F039 Wastewater Aug. 8, 1990. F039 Nonwastewater May 8, 1992. K001 (organics.... K085 All Aug. 8, 1990. K086 (organics) b All Aug. 8, 1988. K086 All others Aug. 8, 1988. K087 All Aug...

40 CFR Appendix Vii to Part 268 - LDR Effective Dates of Surface Disposed Prohibited Hazardous Wastes

Code of Federal Regulations, 2010 CFR

2010-07-01

... Dates of Surface Disposed Wastes (Non-Soil and Debris) Regulated in the LDRS a—Comprehensive List Waste... radioactive wastes June 30, 1994. F039 Wastewater Aug. 8, 1990. F039 Nonwastewater May 8, 1992. K001 (organics.... K085 All Aug. 8, 1990. K086 (organics) b All Aug. 8, 1988. K086 All others Aug. 8, 1988. K087 All Aug...

40 CFR Appendix Vii to Part 268 - LDR Effective Dates of Surface Disposed Prohibited Hazardous Wastes

Code of Federal Regulations, 2014 CFR

2014-07-01

... Dates of Surface Disposed Wastes (Non-Soil and Debris) Regulated in the LDRS a—Comprehensive List Waste... radioactive wastes June 30, 1994. F039 Wastewater Aug. 8, 1990. F039 Nonwastewater May 8, 1992. K001 (organics.... K085 All Aug. 8, 1990. K086 (organics) b All Aug. 8, 1988. K086 All others Aug. 8, 1988. K087 All Aug...

40 CFR Appendix Vii to Part 268 - LDR Effective Dates of Surface Disposed Prohibited Hazardous Wastes

Code of Federal Regulations, 2011 CFR

2011-07-01

... Dates of Surface Disposed Wastes (Non-Soil and Debris) Regulated in the LDRS a—Comprehensive List Waste... radioactive wastes June 30, 1994. F039 Wastewater Aug. 8, 1990. F039 Nonwastewater May 8, 1992. K001 (organics.... K085 All Aug. 8, 1990. K086 (organics) b All Aug. 8, 1988. K086 All others Aug. 8, 1988. K087 All Aug...

40 CFR Appendix Vii to Part 268 - LDR Effective Dates of Surface Disposed Prohibited Hazardous Wastes

Code of Federal Regulations, 2013 CFR

2013-07-01

... Dates of Surface Disposed Wastes (Non-Soil and Debris) Regulated in the LDRS a—Comprehensive List Waste... radioactive wastes June 30, 1994. F039 Wastewater Aug. 8, 1990. F039 Nonwastewater May 8, 1992. K001 (organics.... K085 All Aug. 8, 1990. K086 (organics) b All Aug. 8, 1988. K086 All others Aug. 8, 1988. K087 All Aug...

Dose reduction in LDR brachytherapy by implanted prostate gold fiducial markers.

PubMed

Landry, Guillaume; Reniers, Brigitte; Lutgens, Ludy; Murrer, Lars; Afsharpour, Hossein; de Haas-Kock, Danielle; Visser, Peter; van Gils, Francis; Verhaegen, Frank

2012-03-01

The dosimetric impact of gold fiducial markers (FM) implanted prior to external beam radiotherapy of prostate cancer on low dose rate (LDR) brachytherapy seed implants performed in the context of combined therapy was investigated. A virtual water phantom was designed containing a single FM. Single and multi source scenarios were investigated by performing Monte Carlo dose calculations, along with the influence of varying orientation and distance of the FM with respect to the sources. Three prostate cancer patients treated with LDR brachytherapy for a recurrence following external beam radiotherapy with implanted FM were studied as surrogate cases to combined therapy. FM and brachytherapy seeds were identified on post implant CT scans and Monte Carlo dose calculations were performed with and without FM. The dosimetric impact of the FM was evaluated by quantifying the amplitude of dose shadows and the volume of cold spots. D(90) was reported based on the post implant CT prostate contour. Large shadows are observed in the single source-FM scenarios. As expected from geometric considerations, the shadows are dependent on source-FM distance and orientation. Large dose reductions are observed at the distal side of FM, while at the proximal side a dose enhancement is observed. In multisource scenarios, the importance of shadows appears mitigated, although FM at the periphery of the seed distribution caused underdosage (LDR brachytherapy seed implant dose distributions. Therefore, reduced tumor control could be expected from FM implanted in tumors, although our results are too limited to draw conclusions

40 CFR 268.6 - Petitions to allow land disposal of a waste prohibited under subpart C of part 268.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) LAND DISPOSAL RESTRICTIONS General § 268.6 Petitions to allow land disposal of a waste prohibited under subpart C of part 268. (a) Any person seeking... operator of a land disposal unit receiving restricted waste(s) will comply with other applicable Federal...

40 CFR 268.6 - Petitions to allow land disposal of a waste prohibited under subpart C of part 268.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) LAND DISPOSAL RESTRICTIONS General § 268.6 Petitions to allow land disposal of a waste prohibited under subpart C of part 268. (a) Any person seeking... operator of a land disposal unit receiving restricted waste(s) will comply with other applicable Federal...

40 CFR 268.6 - Petitions to allow land disposal of a waste prohibited under subpart C of part 268.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) LAND DISPOSAL RESTRICTIONS General § 268.6 Petitions to allow land disposal of a waste prohibited under subpart C of part 268. (a) Any person seeking... operator of a land disposal unit receiving restricted waste(s) will comply with other applicable Federal...

40 CFR 268.6 - Petitions to allow land disposal of a waste prohibited under subpart C of part 268.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) LAND DISPOSAL RESTRICTIONS General § 268.6 Petitions to allow land disposal of a waste prohibited under subpart C of part 268. (a) Any person seeking... operator of a land disposal unit receiving restricted waste(s) will comply with other applicable Federal...

40 CFR 268.6 - Petitions to allow land disposal of a waste prohibited under subpart C of part 268.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) LAND DISPOSAL RESTRICTIONS General § 268.6 Petitions to allow land disposal of a waste prohibited under subpart C of part 268. (a) Any person seeking... operator of a land disposal unit receiving restricted waste(s) will comply with other applicable Federal...

Development of a PCR/LDR/flow-through hybridization assay using a capillary tube, probe DNA-immobilized magnetic beads and chemiluminescence detection.

PubMed

Hommatsu, Manami; Okahashi, Hisamitsu; Ohta, Keisuke; Tamai, Yusuke; Tsukagoshi, Kazuhiko; Hashimoto, Masahiko

2013-01-01

A polymerase chain reaction (PCR)/ligase detection reaction (LDR)/flow-through hybridization assay using chemiluminescence (CL) detection was developed for analyzing point mutations in gene fragments with high diagnostic value for colorectal cancers. A flow-through hybridization format using a capillary tube, in which probe DNA-immobilized magnetic beads were packed, provided accelerated hybridization kinetics of target DNA (i.e. LDR product) to the probe DNA. Simple fluid manipulations enabled both allele-specific hybridization and the removal of non-specifically bound DNA in the wash step. Furthermore, the use of CL detection greatly simplified the detection scheme, since CL does not require a light source for excitation of the fluorescent dye tags on the LDR products. Preliminary results demonstrated that this analytical system could detect both homozygous and heterozygous mutations, without the expensive instrumentation and cumbersome procedures required by conventional DNA microarray-based methods.

Impact of point A asymmetry on local control and survival for low dose-rate (LDR) brachytherapy in cervical cancer.

PubMed

Opfermann, Krisha J; Wahlquist, Amy; Watkins, John; Kohler, Matthew; Jenrette, Joseph

2012-03-01

To evaluate whether Point A asymmetry in low dose-rate (LDR) brachytherapy is associated with local control (LC), disease-free survival (DFS) and/or overall survival (OS). A retrospective analysis of disease control and survival outcomes was conducted for patients who underwent LDR brachytherapy for advanced cervical cancer. Institutional protocol entailed concurrent chemotherapy and whole pelvis radiotherapy (WPRT) over 5 weeks, followed by placement of Fletcher-Suit tandem and colpostat applicators at weeks 6 and 8. Objective Point A doses, 80-85 Gy, were accomplished by placement of Cesium-137 (Cs-137) sources. Cox proportional hazards regression models were used to assess associations between disease control and survival endpoints with variables of interest. The records of 50 patients with FIGO stage IB1-IVA cervical cancer undergoing LDR brachytherapy at our institution were identified. Thirty of these patients had asymmetry > 2.5%, and 11 patients had asymmetry > 5%. At a median survivor follow-up of 20.25 months, 15 patients had experienced disease failure (including 5 cervical/vaginal apex only failures and 2 failures encompassing the local site). Right/left dose asymmetry at Point A was associated with statistically significantly inferior LC (p = 0.035) and inferior DFS (p = 0.011) for patients with mean Point A dose of > 80 Gy. Insufficient evidence existed to conclude an association with OS. LDR brachytherapy may be associated with clinically significant dose asymmetry. The present study demonstrates that patients with Point A asymmetry have a higher risk of failure for DFS and LC.

Impact of point A asymmetry on local control and survival for low dose-rate (LDR) brachytherapy in cervical cancer

PubMed Central

Wahlquist, Amy; Watkins, John; Kohler, Matthew; Jenrette, Joseph

2012-01-01

Purpose To evaluate whether Point A asymmetry in low dose-rate (LDR) brachytherapy is associated with local control (LC), disease-free survival (DFS) and/or overall survival (OS). Material and methods A retrospective analysis of disease control and survival outcomes was conducted for patients who underwent LDR brachytherapy for advanced cervical cancer. Institutional protocol entailed concurrent chemotherapy and whole pelvis radiotherapy (WPRT) over 5 weeks, followed by placement of Fletcher-Suit tandem and colpostat applicators at weeks 6 and 8. Objective Point A doses, 80-85 Gy, were accomplished by placement of Cesium-137 (Cs-137) sources. Cox proportional hazards regression models were used to assess associations between disease control and survival endpoints with variables of interest. Results The records of 50 patients with FIGO stage IB1-IVA cervical cancer undergoing LDR brachytherapy at our institution were identified. Thirty of these patients had asymmetry > 2.5%, and 11 patients had asymmetry > 5%. At a median survivor follow-up of 20.25 months, 15 patients had experienced disease failure (including 5 cervical/vaginal apex only failures and 2 failures encompassing the local site). Right/left dose asymmetry at Point A was associated with statistically significantly inferior LC (p = 0.035) and inferior DFS (p = 0.011) for patients with mean Point A dose of > 80 Gy. Insufficient evidence existed to conclude an association with OS. Conclusions LDR brachytherapy may be associated with clinically significant dose asymmetry. The present study demonstrates that patients with Point A asymmetry have a higher risk of failure for DFS and LC. PMID:23346133

Optimal conditions of LDR to protect the kidney from diabetes: exposure to 12.5 mGy X-rays for 8 weeks efficiently protects the kidney from diabetes.

PubMed

Cheng, Jie; Li, Fengsheng; Cui, Jiuwei; Guo, Weiying; Li, Cai; Li, Wei; Wang, Guixia; Xing, Xiao; Gao, Ying; Ge, Yuanyuan; Wang, Guanjun; Cai, Lu

2014-05-08

We reported the attenuation of diabetes-induced renal dysfunction by exposure to multiple low-dose radiation (LDR) at 25 mGy every other day by suppressing renal oxidative damage. We here explored the optimal conditions of LDR to protect the kidney from diabetes. Male C57BL/6J mice with type 1 diabetes were induced with multiple injections of low-dose streptozotocin. Diabetic mice received whole body X-irradiation at a dose of 12.5, 25 or 50 mGy every other day for either 4 or 8 weeks. Age-matched normal mice were similarly irradiated at the dose of 25 mGy for 4 or 8 weeks. The renal function and histopathological changes were examined at the 4th and 8th weeks of the study. Diabetes induced renal dysfunction is shown by the decreased creatinine and increased microalbumin in the urine. Renal oxidative damage, detected by protein nitration and lipid oxidation, and remodeling, reflected by increased expression of connective tissue growth factor, collagen IV and fibronectin, were significantly increased in diabetic mice. All these renal pathological and function changes in diabetic mice were significantly attenuated by exposure to LDR at all regimens, among which, however, exposure to LDR at 12.5 mGy for 8 weeks provided the best protective effect on the kidney of diabetic mice. Our results suggest that whole-body LDR at 12.5 mGy every other day for 8 weeks is the optimal condition of LDR to protect the kidney from diabetes. Copyright © 2014 Elsevier Inc. All rights reserved.

Near constant-time optimal piecewise LDR to HDR inverse tone mapping

NASA Astrophysics Data System (ADS)

Chen, Qian; Su, Guan-Ming; Yin, Peng

2015-02-01

In a backward compatible HDR image/video compression, it is a general approach to reconstruct HDR from compressed LDR as a prediction to original HDR, which is referred to as inverse tone mapping. Experimental results show that 2- piecewise 2nd order polynomial has the best mapping accuracy than 1 piece high order or 2-piecewise linear, but it is also the most time-consuming method because to find the optimal pivot point to split LDR range to 2 pieces requires exhaustive search. In this paper, we propose a fast algorithm that completes optimal 2-piecewise 2nd order polynomial inverse tone mapping in near constant time without quality degradation. We observe that in least square solution, each entry in the intermediate matrix can be written as the sum of some basic terms, which can be pre-calculated into look-up tables. Since solving the matrix becomes looking up values in tables, computation time barely differs regardless of the number of points searched. Hence, we can carry out the most thorough pivot point search to find the optimal pivot that minimizes MSE in near constant time. Experiment shows that our proposed method achieves the same PSNR performance while saving 60 times computation time compared to the traditional exhaustive search in 2-piecewise 2nd order polynomial inverse tone mapping with continuous constraint.

Development of a PCR/LDR/capillary electrophoresis assay with potential for the detection of a beta-thalassemia fetal mutation in maternal plasma.

PubMed

Yi, Ping; Chen, Zhuqin; Yu, Lili; Zheng, Yingru; Liu, Guodong; Xie, Haichang; Zhou, Yuanguo; Zheng, Xiuhui; Han, Jian; Li, Li

2010-08-01

Analysis of fetal DNA in maternal plasma has recently been introduced for non-invasive prenatal diagnosis. We have now investigated the feasibility of polymerase chain reaction (PCR)/ligase detection reaction (LDR)/capillary electrophoresis for the detection of fetal point mutations, such as the beta-thalassemia mutation, IVS2 654(C --> T), in maternal plasma DNA. The sensitivity of LDR/capillary electrophoresis was examined by quantifying the mutant PCR products in the presence of a vast excess of non-mutant competitor template, a situation that mimics the detection of rare fetal mutations in the presence of excess maternal DNA. PCR/LDR/capillary electrophoresis was applied to detect the mutation, IVS2 654(C --> T), in an experimental model at different sensitivity levels and from 10 maternal plasma samples. Our results demonstrated that this approach to detect a low abundance IVS2 654(C --> T) mutation achieved a sensitivity of approximately 1:10,000. The approach was applied to maternal plasma DNA to detect the paternally inherited fetal IVS2 654(C --> T) mutation, and the results were equivalent to those obtained by PCR/reverse dot blot of amniotic fluid cell DNA. PCR/LDR/capillary electrophoresis has a very high sensitivity that can distinguish low abundance single nucleotide differences and can detect paternally inherited fetal point mutations in maternal plasma.

A Multiplex PCR/LDR Assay for Simultaneous Detection and Identification of the NIAID Category B Bacterial Food and Water-borne Pathogens

PubMed Central

Rundell, Mark S.; Pingle, Maneesh; Das, Sanchita; Hussain, Aashiq; Ocheretina, Oksana; Charles, Macarthur; Larone, Davise H.; Spitzer, Eric D.; Golightly, Linnie; Barany, Francis

2014-01-01

Enteric pathogens that cause gastroenteritis remain a major global health concern. The goal of this study was to develop a multiplex PCR/LDR assay for the detection of all NIAID category B bacterial food and water-borne pathogens directly from stool specimens. To validate the PCR/LDR assay, clinical isolates of Campylobacter spp., Vibrio spp., Shigella spp., Salmonella spp., Listeria monocytogenes, Yersinia enterocolitica, and diarrheagenic Escherichia coli were tested. The sensitivity and specificity of the assay was assessed using a large number of seeded culture-negative stool specimens and a smaller set of clinical specimens from Haiti. The overall sensitivity ranged from 91 to 100% (median 100%) depending on the species. For the majority of organisms the sensitivity was 100%. The overall specificity based on initial testing ranged from 98% to 100% depending on the species. After additional testing of discordant samples the lowest specificity was 99.4%. PCR/LDR detected additional category B agents (particularly diarrheagenic E. coli) in 11/40 specimens from Haiti that were culture-positive for V. cholerae and in approximately 1% of routine culture-negative stool specimens from a hospital in New York. This study demonstrated the ability of the PCR/LDR assay to detect a large comprehensive panel of category B enteric bacterial pathogens as well as mixed infections. This type of assay has the potential to provide earlier warnings of possible public health threats and more accurate surveillance of food and water-borne pathogens. PMID:24709368

LDR structural experiment definition

NASA Technical Reports Server (NTRS)

Russell, R. A.

1988-01-01

A system study to develop the definition of a structural flight experiment for a large precision segmented reflector on the Space Station was accomplished by the Boeing Aerospace Company for NASA's Langley Research Center. The objective of the study was to use a Large Deployable Reflector (LDR) baseline configuration as the basis for focusing an experiment definition, so that the resulting accommodation requirements and interface constraints could be used as part of the mission requirements data base for Space Station. The primary objectives of the first experiment are to construct the primary mirror support truss and to determine its structural and thermal characteristics. Addition of an optical bench, thermal shield and primary mirror segments, and alignment of the optical components, would occur on a second experiment. The structure would then be moved to the payload point system for pointing, optical control, and scientific optical measurement for a third experiment. Experiment 1 will deploy the primary support truss while it is attached to the instrument module structure. The ability to adjust the mirror attachment points and to attach several dummy primary mirror segments with a robotic system will also be demonstrated. Experiment 2 will be achieved by adding new components and equipment to experiment one. Experiment 3 will demonstrate advanced control strategies, active adjustment of the primary mirror alignment, and technologies associated with optical sensing.

LDR brachytherapy: can low dose rate hypersensitivity from the "inverse" dose rate effect cause excessive cell killing to peripherial connective tissues and organs?

PubMed

Leonard, B E; Lucas, A C

2009-02-01

Examined here are the possible effects of the "inverse" dose rate effect (IDRE) on low dose rate (LDR) brachytherapy. The hyper-radiosensitivity and induced radioresistance (HRS/IRR) effect benefits cell killing in radiotherapy, and IDRE and HRS/IRR seem to be generated from the same radioprotective mechanisms. We have computed the IDRE excess cell killing experienced in LDR brachytherapy using permanent seed implants. We conclude, firstly, that IDRE is a dose rate-dependent manifestation of HRS/IRR. Secondly, the presence of HRS/IRR or IDRE in a cell species or tissue must be determined by direct dose-response measurements. Thirdly, a reasonable estimate is that 50-80% of human adjoining connective and organ tissues experience IDRE from permanent implanted LDR brachytherapy. If IDRE occurs for tissues at point A for cervical cancer, the excess cell killing will be about a factor of 3.5-4.0 if the initial dose rate is 50-70 cGy h(-1). It is greater for adjacent tissues at lower dose rates and higher for lower initial dose rates at point A. Finally, higher post-treatment complications are observed in LDR brachytherapy, often for unknown reasons. Some of these are probably a result of IDRE excess cell killing. Measurements of IDRE need be performed for connective and adjacent organ tissues, i.e. bladder, rectum, urinary tract and small bowels. The measured dose rate-dependent dose responses should extended to <10 cGy h(-1) and involve multiple patients to detect patient variability. Results may suggest a preference for high dose rate brachytherapy or LDR brachytherapy without permanent retention of the implant seeds (hence the dose rates in peripheral tissues and organs remain above IDRE thresholds).

An industry perspective on commercial radioactive waste disposal conditions and trends.

PubMed

Romano, Stephen A

2006-11-01

The United States is presently served by Class-A, -B and -C low-level radioactive waste and naturally-occurring and accelerator-produced radioactive material disposal sites in Washington and South Carolina; a Class-A and mixed waste disposal site in Utah that also accepts naturally-occurring radioactive material; and hazardous and solid waste facilities and uranium mill tailings sites that accept certain radioactive materials on a site-specific basis. The Washington site only accepts low-level radioactive waste from 11 western states due to interstate Compact restrictions on waste importation. The South Carolina site will be subject to geographic service area restrictions beginning 1 July 2008, after which only three states will have continued access. The Utah site dominates the commercial Class-A and mixed waste disposal market due to generally lower state fees than apply in South Carolina. To expand existing commercial services, an existing hazardous waste site in western Texas is seeking a Class-A, -B and -C and mixed waste disposal license. With that exception, no new Compact facilities are proposed. This fluid, uncertain situation has inspired national level rulemaking initiatives and policy studies, as well as alternative disposal practices for certain low-activity materials.

BrachyView: Combining LDR seed positions with transrectal ultrasound imaging in a prostate gel phantom.

PubMed

Alnaghy, S; Cutajar, D L; Bucci, J A; Enari, K; Safavi-Naeini, M; Favoino, M; Tartaglia, M; Carriero, F; Jakubek, J; Pospisil, S; Lerch, M; Rosenfeld, A B; Petasecca, M

2017-02-01

BrachyView is a novel in-body imaging system which aims to provide LDR brachytherapy seeds position reconstruction within the prostate in real-time. The first prototype is presented in this study: the probe consists of a gamma camera featuring three single cone pinhole collimators embedded in a tungsten tube, above three, high resolution pixelated detectors (Timepix). The prostate was imaged with a TRUS system using a sagittal crystal with a 2.5mm slice thickness. Eleven needles containing a total of thirty 0.508U 125 I seeds were implanted under ultrasound guidance. A CT scan was used to localise the seed positions, as well as provide a reference when performing the image co-registration between the BrachyView coordinate system and the TRUS coordinate system. An in-house visualisation software interface was developed to provide a quantitative 3D reconstructed prostate based on the TRUS images and co-registered with the LDR seeds in situ. A rigid body image registration was performed between the BrachyView and TRUS systems, with the BrachyView and CT-derived source locations compared. The reconstructed seed positions determined by the BrachyView probe showed a maximum discrepancy of 1.78mm, with 75% of the seeds reconstructed within 1mm of their nominal location. An accurate co-registration between the BrachyView and TRUS coordinate system was established. The BrachyView system has shown its ability to reconstruct all implanted LDR seeds within a tissue equivalent prostate gel phantom, providing both anatomical and seed position information in a single interface. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

Absolute measurement of LDR brachytherapy source emitted power: Instrument design and initial measurements.

PubMed

Malin, Martha J; Palmer, Benjamin R; DeWerd, Larry A

2016-02-01

Energy-based source strength metrics may find use with model-based dose calculation algorithms, but no instruments exist that can measure the energy emitted from low-dose rate (LDR) sources. This work developed a calorimetric technique for measuring the power emitted from encapsulated low-dose rate, photon-emitting brachytherapy sources. This quantity is called emitted power (EP). The measurement methodology, instrument design and performance, and EP measurements made with the calorimeter are presented in this work. A calorimeter operating with a liquid helium thermal sink was developed to measure EP from LDR brachytherapy sources. The calorimeter employed an electrical substitution technique to determine the power emitted from the source. The calorimeter's performance and thermal system were characterized. EP measurements were made using four (125)I sources with air-kerma strengths ranging from 2.3 to 5.6 U and corresponding EPs of 0.39-0.79 μW, respectively. Three Best Medical 2301 sources and one Oncura 6711 source were measured. EP was also computed by converting measured air-kerma strengths to EPs through Monte Carlo-derived conversion factors. The measured EP and derived EPs were compared to determine the accuracy of the calorimeter measurement technique. The calorimeter had a noise floor of 1-3 nW and a repeatability of 30-60 nW. The calorimeter was stable to within 5 nW over a 12 h measurement window. All measured values agreed with derived EPs to within 10%, with three of the four sources agreeing to within 4%. Calorimeter measurements had uncertainties ranging from 2.6% to 4.5% at the k = 1 level. The values of the derived EPs had uncertainties ranging from 2.9% to 3.6% at the k = 1 level. A calorimeter capable of measuring the EP from LDR sources has been developed and validated for (125)I sources with EPs between 0.43 and 0.79 μW.

A multiplex PCR/LDR assay for simultaneous detection and identification of the NIAID category B bacterial food and water-borne pathogens.

PubMed

Rundell, Mark S; Pingle, Maneesh; Das, Sanchita; Hussain, Aashiq; Ocheretina, Oksana; Charles, Macarthur; Larone, Davise H; Spitzer, Eric D; Golightly, Linnie; Barany, Francis

2014-06-01

Enteric pathogens that cause gastroenteritis remain a major global health concern. The goal of this study was to develop a multiplex PCR/ligation detection reaction (LDR) assay for the detection of all NIAID category B bacterial food and water-borne pathogens directly from stool specimens. To validate the PCR/LDR assay, clinical isolates of Campylobacter spp., Vibrio spp., Shigella spp., Salmonella spp., Listeria monocytogenes, Yersinia enterocolitica, and diarrheagenic Escherichia coli were tested. The sensitivity and specificity of the assay were assessed using a large number of seeded culture-negative stool specimens and a smaller set of clinical specimens from Haiti. The overall sensitivity ranged from 91% to 100% (median 100%) depending on the species. For the majority of organisms, the sensitivity was 100%. The overall specificity based on initial testing ranged from 98% to 100% depending on the species. After additional testing of discordant samples, the lowest specificity was 99.4%. PCR/LDR detected additional category B agents (particularly diarrheagenic E. coli) in 11/40 specimens from Haiti that were culture-positive for V. cholerae and in approximately 1% of routine culture-negative stool specimens from a hospital in New York. This study demonstrated the ability of the PCR/LDR assay to detect a large comprehensive panel of category B enteric bacterial pathogens as well as mixed infections. This type of assay has the potential to provide earlier warnings of possible public health threats and more accurate surveillance of food and water-borne pathogens. Copyright © 2014 Elsevier Inc. All rights reserved.

Minimal percentage of dose received by 90% of the urethra (%UD90) is the most significant predictor of PSA bounce in patients who underwent low-dose-rate brachytherapy (LDR-brachytherapy) for prostate cancer.

PubMed

Tanaka, Nobumichi; Asakawa, Isao; Fujimoto, Kiyohide; Anai, Satoshi; Hirayama, Akihide; Hasegawa, Masatoshi; Konishi, Noboru; Hirao, Yoshihiko

2012-09-14

To clarify the significant clinicopathological and postdosimetric parameters to predict PSA bounce in patients who underwent low-dose-rate brachytherapy (LDR-brachytherapy) for prostate cancer. We studied 200 consecutive patients who received LDR-brachytherapy between July 2004 and November 2008. Of them, 137 patients did not receive neoadjuvant or adjuvant androgen deprivation therapy. One hundred and forty-two patients were treated with LDR-brachytherapy alone, and 58 were treated with LDR-brachytherapy in combination with external beam radiation therapy. The cut-off value of PSA bounce was 0.1 ng/mL. The incidence, time, height, and duration of PSA bounce were investigated. Clinicopathological and postdosimetric parameters were evaluated to elucidate independent factors to predict PSA bounce in hormone-naïve patients who underwent LDR-brachytherapy alone. Fifty patients (25%) showed PSA bounce and 10 patients (5%) showed PSA failure. The median time, height, and duration of PSA bounce were 17 months, 0.29 ng/mL, and 7.0 months, respectively. In 103 hormone-naïve patients treated with LDR-brachytherapy alone, and univariate Cox proportional regression hazard model indicated that age and minimal percentage of the dose received by 30% and 90% of the urethra were independent predictors of PSA bounce. With a multivariate Cox proportional regression hazard model, minimal percentage of the dose received by 90% of the urethra was the most significant parameter of PSA bounce. Minimal percentage of the dose received by 90% of the urethra was the most significant predictor of PSA bounce in hormone-naïve patients treated with LDR-brachytherapy alone.

Guidebook: Quality Assurance/Quality Control Procedures for Submission of Data for the Land Disposal Restrictions (LDR) Program

EPA Pesticide Factsheets

This document explains how to generate data which characterizes the performance of hazardous waste treatment systems in terms of the composition of treated hazardous waste streams plus treatment system operation and design.

75 FR 60457 - Underground Injection Control Program Hazardous Waste Injection Restrictions; Petition for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-30

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9208-4] Underground Injection Control Program Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection Dow Chemical Company (DOW... Petition. SUMMARY: Notice is hereby given that an exemption to the land disposal restrictions under the...

[Implants with 32P-foils for LDR-brachytherapy of benign stenosis in urology and gastroenterology].

PubMed

Assmann, Walter; Becker, Ricarda; Otto, Henrike; Bader, Markus; Clemente, Lucas; Reinhardt, Sabine; Schäfer, Claus; Schirra, Jörg; Uschold, Stephanie; Welzmüller, Andreas; Sroka, Ronald

2013-02-01

For LDR-brachytherapy, a limited number of implant geometries and materials are available. To avoid wound healing related hyper-proliferation (stenosis, keloids) a novel radioactive foil system was developed based on beta emitting (32)P, which can be easily integrated in existing implants such as urethral catheters or bile duct stents. As substrate material for these foils PEEK (polyetherethercetone) was chosen because of its radiation hardness during neutron activation of (32)P. The activity was determined by liquid scintillation counting and gamma spectroscopy, dose distributions were measured with scintillation detectors and radiochromic films. The correlation between activity and dose was checked by Monte-Carlo-simulations (Geant4). Prototypes of the (32)P-implants have shown in wash-out tests the required tightness for sealed radioactive sources. In animal tests on urethra and bile duct, the uncomplicated and save application of (32)P-foils mounted on standard implants has been demonstrated, which is almost unchanged due to the simple radiation protection with plexiglass. This concept of radioactive implants with integrated (32)P-foils could extend essentially the application possibilities of LDR-brachytherapy. Copyright © 2012. Published by Elsevier GmbH.

76 FR 55908 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

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77 FR 26755 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

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PCR/LDR/universal array platforms for the diagnosis of infectious disease.

PubMed

Pingle, Maneesh; Rundell, Mark; Das, Sanchita; Golightly, Linnie M; Barany, Francis

2010-01-01

Infectious diseases account for between 14 and 17 million deaths worldwide each year. Accurate and rapid diagnosis of bacterial, fungal, viral, and parasitic infections is therefore essential to reduce the morbidity and mortality associated with these diseases. Classical microbiological and serological methods have long served as the gold standard for diagnosis but are increasingly being replaced by molecular diagnostic methods that demonstrate increased sensitivity and specificity and provide an identification of the etiologic agent in a shorter period of time. PCR/LDR coupled with universal array detection provides a highly sensitive and specific platform for the detection and identification of bacterial and viral infections.

PCR/LDR/Universal Array Platforms for the Diagnosis of Infectious Disease

PubMed Central

Pingle, Maneesh; Rundell, Mark; Das, Sanchita; Golightly, Linnie M.; Barany, Francis

2015-01-01

Infectious diseases account for between 14 and 17 million deaths worldwide each year. Accurate and rapid diagnosis of bacterial, fungal, viral, and parasitic infections is therefore essential to reduce the morbidity and mortality associated with these diseases. Classical microbiological and serological methods have long served as the gold standard for diagnosis but are increasingly being replaced by molecular diagnostic methods that demonstrate increased sensitivity and specificity and provide an identification of the etiologic agent in a shorter period of time. PCR/LDR coupled with universal array detection provides a highly sensitive and specific platform for the detection and identification of bacterial and viral infections. PMID:20217576

78 FR 76294 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

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2013-12-17

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9 CFR 94.7 - Disposal of animals, meats, and other articles ineligible for importation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Disposal of animals, meats, and other... RESTRICTED IMPORTATIONS § 94.7 Disposal of animals, meats, and other articles ineligible for importation. (a) Ruminants and swine, and fresh (chilled or frozen) meats, prohibited importation under §§ 94.1, 94.8, 94.9...

HDR and LDR Brachytherapy in the Treatment of Lip Cancer: the Experience of the Catalan Institute of Oncology.

PubMed

Ayerra, Arrate Querejeta; Mena, Estefanía Palacios; Fabregas, Joan Pera; Miguelez, Cristina Gutiérrez; Guedea, Ferran

2010-03-01

Lip cancer can be treated by surgery, external radiotherapy, and/or brachytherapy (BT). In recent years, BT has become increasingly favored for this type of cancer. The aim of the present study was to analyze local control and survival of patients treated at our institution between July 1989 and June 2008. We performed a retrospective study of 121 patients (109 males and 12 females) who underwent lip cancer brachytherapy from July 1989 to June 2008. Median age was 67 years and median follow-up was 31.8 months (range 20-188 months). Out of 121 patients, 100 (82.6%) were treated with low dose rate (LDR) BT while the remaining 21 patients (17.4%) received high dose rate (HDR) BT. The most common cell type was squamous cell carcinoma (115 cases; 95%) and most tumors were located on the lower lip (107 patients; 88.4%). Most cases were either stage T1 (62 patients; 51.2%), or T2 (44 cases; 36.4%). After 15 years of follow-up, overall survival was 89.5%, cause-specific survival 97.8%, and disease-free survival 86.6%. Local, regional, and distant control at 15 years were 90%, 92%, and 98.8%, respectively. Grade 3 mucosal toxicity was observed in 23% of patients treated with LDR compared to 33% of HDR patients, and grade 4 mucosal toxicity in 9% versus 0% in the HDR group. Our findings confirm that brachytherapy is an effective treatment for lip cancer. The results from our series are in line with those published elsewhere. Based on our limited data, HDR appears to be equally as good as LDR, although this needs to be confirmed by further studies.

Low dose rate brachytherapy (LDR-BT) as monotherapy for early stage prostate cancer in Italy: practice and outcome analysis in a series of 2237 patients from 11 institutions

PubMed Central

Fellin, Giovanni; Mirri, Maria A; Santoro, Luigi; Divan, Claudio; Mussari, Salvatore; Ziglio, Francesco; La Face, Beniamino; Barbera, Fernando; Buglione, Michela; Bandera, Laura; Ghedi, Barbara; Di Muzio, Nadia G; Losa, Andrea; Mangili, Paola; Nava, Luciano; Chiarlone, Renato; Ciscognetti, Nunzia; Gastaldi, Emilio; Cattani, Federica; Spoto, Ruggero; Vavassori, Andrea; Giglioli, Francesca R; Guarneri, Alessia; Cerboneschi, Valentina; Mignogna, Marcello; Paoluzzi, Mauro; Ravaglia, Valentina; Chiumento, Costanza; Clemente, Stefania; Fusco, Vincenzo; Santini, Roberto; Stefanacci, Marco; Mangiacotti, Francesco P; Martini, Marco; Palloni, Tiziana; Schinaia, Giuseppe; Lazzari, Grazia; Silvano, Giovanni; Magrini, Stefano; Ricardi, Umberto; Santoni, Riccardo; Orecchia, Roberto

2016-01-01

Objective: Low-dose-rate brachytherapy (LDR-BT) in localized prostate cancer is available since 15 years in Italy. We realized the first national multicentre and multidisciplinary data collection to evaluate LDR-BT practice, given as monotherapy, and outcome in terms of biochemical failure. Methods: Between May 1998 and December 2011, 2237 patients with early-stage prostate cancer from 11 Italian community and academic hospitals were treated with iodine-125 (125I) or palladium-103 LDR-BT as monotherapy and followed up for at least 2 years. 125I seeds were implanted in 97.7% of the patients: the mean dose received by 90% of target volume was 145 Gy; the mean target volume receiving 100% of prescribed dose (V100) was 91.1%. Biochemical failure-free survival (BFFS), disease-specific survival (DSS) and overall survival (OS) were estimated using Kaplan–Meier method. Log-rank test and multivariable Cox regression were used to evaluate the relationship of covariates with outcomes. Results: Median follow-up time was 65 months. 5- and 7-year DSS, OS and BFFS were 99 and 98%, 94 and 89%, and 92 and 88%, respectively. At multivariate analysis, the National Comprehensive Cancer Network score (p < 0.0001) and V100 (p = 0.09) were correlated with BFFS, with V100 effect significantly different between patients at low risk and those at intermediate/high risk (p = 0.04). Short follow-up and lack of toxicity data represent the main limitations for a global evaluation of LDR-BT. Conclusion: This first multicentre Italian report confirms LDR-BT as an excellent curative modality for low-/intermediate-risk prostate cancer. Advances in knowledge: Multidisciplinary teams may help to select adequately patients to be treated with brachytherapy, with a direct impact on the implant quality and, possibly, on outcome. PMID:27384381

Low dose rate brachytherapy (LDR-BT) as monotherapy for early stage prostate cancer in Italy: practice and outcome analysis in a series of 2237 patients from 11 institutions.

PubMed

Fellin, Giovanni; Mirri, Maria A; Santoro, Luigi; Jereczek-Fossa, Barbara A; Divan, Claudio; Mussari, Salvatore; Ziglio, Francesco; La Face, Beniamino; Barbera, Fernando; Buglione, Michela; Bandera, Laura; Ghedi, Barbara; Di Muzio, Nadia G; Losa, Andrea; Mangili, Paola; Nava, Luciano; Chiarlone, Renato; Ciscognetti, Nunzia; Gastaldi, Emilio; Cattani, Federica; Spoto, Ruggero; Vavassori, Andrea; Giglioli, Francesca R; Guarneri, Alessia; Cerboneschi, Valentina; Mignogna, Marcello; Paoluzzi, Mauro; Ravaglia, Valentina; Chiumento, Costanza; Clemente, Stefania; Fusco, Vincenzo; Santini, Roberto; Stefanacci, Marco; Mangiacotti, Francesco P; Martini, Marco; Palloni, Tiziana; Schinaia, Giuseppe; Lazzari, Grazia; Silvano, Giovanni; Magrini, Stefano; Ricardi, Umberto; Santoni, Riccardo; Orecchia, Roberto

2016-09-01

Low-dose-rate brachytherapy (LDR-BT) in localized prostate cancer is available since 15 years in Italy. We realized the first national multicentre and multidisciplinary data collection to evaluate LDR-BT practice, given as monotherapy, and outcome in terms of biochemical failure. Between May 1998 and December 2011, 2237 patients with early-stage prostate cancer from 11 Italian community and academic hospitals were treated with iodine-125 ((125)I) or palladium-103 LDR-BT as monotherapy and followed up for at least 2 years. (125)I seeds were implanted in 97.7% of the patients: the mean dose received by 90% of target volume was 145 Gy; the mean target volume receiving 100% of prescribed dose (V100) was 91.1%. Biochemical failure-free survival (BFFS), disease-specific survival (DSS) and overall survival (OS) were estimated using Kaplan-Meier method. Log-rank test and multivariable Cox regression were used to evaluate the relationship of covariates with outcomes. Median follow-up time was 65 months. 5- and 7-year DSS, OS and BFFS were 99 and 98%, 94 and 89%, and 92 and 88%, respectively. At multivariate analysis, the National Comprehensive Cancer Network score (p < 0.0001) and V100 (p = 0.09) were correlated with BFFS, with V100 effect significantly different between patients at low risk and those at intermediate/high risk (p = 0.04). Short follow-up and lack of toxicity data represent the main limitations for a global evaluation of LDR-BT. This first multicentre Italian report confirms LDR-BT as an excellent curative modality for low-/intermediate-risk prostate cancer. Multidisciplinary teams may help to select adequately patients to be treated with brachytherapy, with a direct impact on the implant quality and, possibly, on outcome.

Multiplex quantification of 16S rDNA of predominant bacteria group within human fecal samples by polymerase chain reaction--ligase detection reaction (PCR-LDR).

PubMed

Li, Kai; Chen, Bei; Zhou, Yuxun; Huang, Rui; Liang, Yinming; Wang, Qinxi; Xiao, Zhenxian; Xiao, Junhua

2009-03-01

A new method, based on ligase detection reaction (LDR), was developed for quantitative detection of multiplex PCR amplicons of 16S rRNA genes present in complex mixtures (specifically feces). LDR has been widely used in single nucleotide polymorphism (SNP) assay but never applied for quantification of multiplex PCR products. This method employs one pair of DNA probes, one of which is labeled with fluorescence for signal capture, complementary to the target sequence. For multiple target sequence analysis, probes were modified with different lengths of polyT at the 5' end and 3' end. Using a DNA sequencer, these ligated probes were separated and identified by size and dye color. Then, relative abundance of target DNA were normalized and quantified based on the fluorescence intensities and exterior size standards. 16S rRNA gene of three preponderant bacteria groups in human feces: Clostridium coccoides, Bacteroides and related genera, and Clostridium leptum group, were amplified and cloned into plasmid DNA so as to make standard curves. After PCR-LDR analysis, a strong linear relationship was found between the florescence intensity and the diluted plasmid DNA concentrations. Furthermore, based on this method, 100 human fecal samples were quantified for the relative abundance of the three bacterial groups. Relative abundance of C. coccoides was significantly higher in elderly people in comparison with young adults, without gender differences. Relative abundance of Bacteroides and related genera and C. leptum group were significantly higher in young and middle aged than in the elderly. Regarding the whole set of sample, C. coccoides showed the highest relative abundance, followed by decreasing groups Bacteroides and related genera, and C. leptum. These results imply that PCR-LDR can be feasible and flexible applied to large scale epidemiological studies.

SU-E-T-259: Development of a Primary Standard for LDR Brachytherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shen, H; McEwen, M

Purpose: The National Research Council initiated a program in 2012 to develop a primary standard to calibrate I-125 and Pd-103 sources used for LDR brachytherapy and disseminate this through calibration services to Canadian users. This will simplify procedures as Canadian cancer centres currently have to ship instruments to the US. Methods: The standard is based on a commercial version of the wide-angle free air chamber (WAFAC) pioneered by NIST. Significant enhancements were implemented to improve signal-to-noise and measurement reproducibility and eliminate electric field effects. Validation of this ionization chamber was then carried out in a low-energy X -ray beam (∼more » 31 keV) where the dose rate had been previously established using the existing NRC primary standard free-air chamber. As a final component of this initial testing, measurements were made with a set of I-125 seeds (with air kerma strength traceable to NIST). Results: Excellent agreement of the two NRC free-air chambers was obtained within the combined standard uncertainty of 0.5 %. However, it was found that the WAFAC response is very sensitive to the beam geometry (distance from the source, diameter of the beam-defining aperture, etc) and Monte Carlo calculations, carried out to evaluate these geometry corrections, have confirmed the experimental results. The results for the seed measurements indicated a precision of better than 1 % is achievable for a reasonable acquisition time and the air kerma strength agreed with the manufacturer (NIST-traceable) value within 2 %. Conclusion: The prototype primary standard for LDR brachytherapy has met accuracy target of 3 % for the determination of air kerma strength. Work is ongoing to refine operation of the device and develop the calibration protocol for clinical users, with an anticipated launch of a calibration service in late 2015.« less

Land Disposal Restrictions for Third Third Scheduled Wastes - Federal Register Notice, January 31, 1991

EPA Pesticide Factsheets

On June 1, 1990, EPA published regulations promulgating congressionally-mandated prohibitions on land disposal of certain hazardous wastes. This notice corrects errors and clarifies the language of the June 1, 1990 final rule.

Land Disposal Restrictions for Third Third Scheduled Wastes - Federal Register Notice, March 6, 1992

EPA Pesticide Factsheets

On June 1, 1990, EPA published regulations promulgating congressionally mandated prohibitions on land disposal of certain hazardous wastes. This notice corrects errors and clarifies the language in the preamble and regulations of the final rule.

Brachytherapy for Buccal Cancer: From Conventional Low Dose Rate (LDR) or Mold Technique to High Dose Rate Interstitial Brachytherapy (HDR-ISBT).

PubMed

Kotsuma, Tadayuki; Yamazaki, Hideya; Masui, Koji; Yoshida, Ken; Shimizutani, Kimishige; Akiyama, Hironori; Murakami, Shumei; Isohashi, Fumiaki; Yoshioka, Yasuo; Ogawa, Kazuhiko; Tanaka, Eiichi

2017-12-01

To examine the effectiveness of newly-installed high-dose-rate interstitial brachytherapy (HDR-ISBT) for buccal cancer. We retrospectively reviewed 36 patients (25 men and 11 women) with buccal cancer treated with curative brachytherapy with or without external radiotherapy with a median follow-up of 99 months. A total of 15 HDR-ISBT (median 48 Gy/ 8 fractions, range=24-60 Gy) patients were compared to conventional 15 cases LDR-ISBT (70 Gy, range=42.8-110 Gy) and 7 molds techniques (15 Gy, range=9-74 Gy). A total of 31 patients also underwent external radiotherapy (30 Gy, range=24-48 Gy). They comprised of 3T1, 23 T2, 8 T3, 3 T4 including 11 node positive cases. HDR-ISBT provided 82% of local control rate at 5 years, whereas conventional brachytherapy showed 72% [p=0.44; LDR-ISBT (65%), mold therapy (85.7%)]. Patients with early lesions (T1-2 or stage I-II) showed better local control rates than those with advanced lesions (T3-4 or stage III-IV). Severe late grade 3 complications developed in two patients treated with LDR-ISBT and EBRT. There is no significant difference in toxicity grade ≤2 between conventional brachytherapy (5/15=33%) and HDR-ISBT (7/32=32%, p=0.92). HDR-ISBT achieved good and comparable local control rates to conventional brachytherapy without elevating the toxicity. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Biological effective dose evaluation in gynaecological brachytherapy: LDR and HDR treatments, dependence on radiobiological parameters, and treatment optimisation.

PubMed

Bianchi, C; Botta, F; Conte, L; Vanoli, P; Cerizza, L

2008-10-01

This study was undertaken to compare the biological efficacy of different high-dose-rate (HDR) and low-dose-rate (LDR) treatments of gynaecological lesions, to identify the causes of possible nonuniformity and to optimise treatment through customised calculation. The study considered 110 patients treated between 2001 and 2006 with external beam radiation therapy and/or brachytherapy with either LDR (afterloader Selectron, (137)Cs) or HDR (afterloader microSelectron Classic, (192)Ir). The treatments were compared in terms of biologically effective dose (BED) to the tumour and to the rectum (linear-quadratic model) by using statistical tests for comparisons between independent samples. The difference between the two treatments was statistically significant in one case only. However, within each technique, we identified considerable nonuniformity in therapeutic efficacy due to differences in fractionation schemes and overall treatment time. To solve this problem, we created a Microsoft Excel spreadsheet allowing calculation of the optimal treatment for each patient: best efficacy (BED(tumour)) without exceeding toxicity threshold (BED(rectum)). The efficacy of a treatment may vary as a result of several factors. Customised radiobiological evaluation is a useful adjunct to clinical evaluation in planning equivalent treatments that satisfy all dosimetric constraints.

Simulation requirements for the Large Deployable Reflector (LDR)

NASA Technical Reports Server (NTRS)

Soosaar, K.

1984-01-01

Simulation tools for the large deployable reflector (LDR) are discussed. These tools are often the transfer function variety equations. However, transfer functions are inadequate to represent time-varying systems for multiple control systems with overlapping bandwidths characterized by multi-input, multi-output features. Frequency domain approaches are the useful design tools, but a full-up simulation is needed. Because of the need for a dedicated computer for high frequency multi degree of freedom components encountered, non-real time smulation is preferred. Large numerical analysis software programs are useful only to receive inputs and provide output to the next block, and should be kept out of the direct loop of simulation. The following blocks make up the simulation. The thermal model block is a classical heat transfer program. It is a non-steady state program. The quasistatic block deals with problems associated with rigid body control of reflector segments. The steady state block assembles data into equations of motion and dynamics. A differential raytrace is obtained to establish a change in wave aberrations. The observation scene is described. The focal plane module converts the photon intensity impinging on it into electron streams or into permanent film records.

Divergently overlapping cis-encoded antisense RNA regulating toxin-antitoxin systems from E. coli: hok/sok, ldr/rdl, symE/symR.

PubMed

Kawano, Mitsuoki

2012-12-01

Toxin-antitoxin (TA) systems are categorized into three classes based on the type of antitoxin. In type I TA systems, the antitoxin is a small antisense RNA that inhibits translation of small toxic proteins by binding to the corresponding mRNAs. Those type I TA systems were originally identified as plasmid stabilization modules rendering a post-segregational killing (PSK) effect on the host cells. The type I TA loci also exist on the Escherichia coli chromosome but their biological functions are less clear. Genetic organization and regulatory elements of hok/sok and ldr/rdl families are very similar and the toxins are predicted to contain a transmembrane domain, but otherwise share no detectable sequence similarity. This review will give an overview of the type I TA modules of E. coli K-12, especially hok/sok, ldr/rdl and SOS-inducible symE/symR systems, which are regulated by divergently overlapping cis-encoded antisense RNAs.

Hybrid deployable support truss designs for LDR

NASA Technical Reports Server (NTRS)

Hedgepeth, J.

1988-01-01

Concepts for a 20-meter diameter Large Deployable Reflector (LDR) deployable truss backup structure, and analytical predictions of its structural characteristics are discussed. The concept shown is referred to as the SIXPAC; It is a combination of the PACTRUSS concept and a single-fold beam, which would make up the desired backup structure. One advantage of retaining the PACTRUSS concept is its packaging density and its capability for synchronous deployment. Various 2-meter hexagonal panel arrangements are possible for this Hybrid PACTRUSS structure depending on the panel-to-structure attachment strategies used. Static analyses of the SIXPAC using various assumptions for truss designs and panel masses of 10 kg sq meters were performed to predict the tip displacement of the structure when supported at the center. The tip displacement ranged from 0.20 to 0.44 mm without the panel mass, and from 0.9 to 3.9 mm with the panel mass (in a 1-g field). The data indicate that the structure can be adequately ground tested to validate its required performance in space, assuming the required performance in space is approximately 100 microns. The static displacement at the tip of the structure when subjected to an angular acceleration of 0.001 rad/sec squared were estimated to range from 0.8 to 7.5 microns, depending on the type of truss elements.

System concept for a moderate cost Large Deployable Reflector (LDR)

NASA Technical Reports Server (NTRS)

Swanson, P. N.; Breckinridge, J. B.; Diner, A.; Freeland, R. E.; Irace, W. R.; Mcelroy, P. M.; Meinel, A. B.; Tolivar, A. F.

1986-01-01

A study was carried out at JPL during the first quarter of 1985 to develop a system concept for NASA's LDR. Major features of the concept are a four-mirror, two-stage optical system; a lightweight structural composite segmented primary reflector; and a deployable truss backup structure with integral thermal shield. The two-stage optics uses active figure control at the quaternary reflector located at the primary reflector exit pupil, allowing the large primary to be passive. The lightweight composite reflector panels limit the short-wavelength operation to approximately 30 microns but reduce the total primary reflector weight by a factor of 3 to 4 over competing technologies. On-orbit thermal analysis indicates a primary reflector equilibrium temperature of less than 200 K with a maximum gradient of about 5 C across the 20-m aperture. Weight and volume estimates are consistent with a single Shuttle launch, and are based on Space Station assembly and checkout.

The end-of-life disposal of satellites in libration-point orbits using solar radiation pressure

NASA Astrophysics Data System (ADS)

Soldini, Stefania; Colombo, Camilla; Walker, Scott

2016-04-01

This paper proposes an end-of-life propellant-free disposal strategy for libration-point orbits which uses solar radiation pressure to restrict the evolution of the spacecraft motion. The spacecraft is initially disposed into the unstable manifold leaving the libration-point orbit, before a reflective sun-pointing surface is deployed to enhance the effect of solar radiation pressure. Therefore, the consequent increase in energy prevents the spacecraft's return to Earth. Three European Space Agency missions are selected as test case scenarios: Herschel, SOHO and Gaia. Guidelines for the end-of-life disposal of future libration-point orbit missions are proposed and a preliminary study on the effect of the Earth's orbital eccentricity on the disposal strategy is shown for the Gaia mission.

Evaluation of the effect of prostate volume change on tumor control probability in LDR brachytherapy.

PubMed

Knaup, Courtney; Mavroidis, Panayiotis; Stathakis, Sotirios; Smith, Mark; Swanson, Gregory; Papanikolaou, Niko

2011-09-01

This study evaluates low dose-rate brachytherapy (LDR) prostate plans to determine the biological effect of dose degradation due to prostate volume changes. In this study, 39 patients were evaluated. Pre-implant prostate volume was determined using ultrasound. These images were used with the treatment planning system (Nucletron Spot Pro 3.1(®)) to create treatment plans using (103)Pd seeds. Following the implant, patients were imaged using CT for post-implant dosimetry. From the pre and post-implant DVHs, the biologically equivalent dose and the tumor control probability (TCP) were determined using the biologically effective uniform dose. The model used RBE = 1.75 and α/β = 2 Gy. The prostate volume changed between pre and post implant image sets ranged from -8% to 110%. TCP and the mean dose were reduced up to 21% and 56%, respectively. TCP is observed to decrease as the mean dose decreases to the prostate. The post-implant tumor dose was generally observed to decrease, compared to the planned dose. A critical uniform dose of 130 Gy was established. Below this dose, TCP begins to fall-off. It was also determined that patients with a small prostates were more likely to suffer TCP decrease. The biological effect of post operative prostate growth due to operative trauma in LDR was evaluated using the concept. The post-implant dose was lower than the planned dose due to an increase of prostate volume post-implant. A critical uniform dose of 130 Gy was determined, below which TCP begun to decline.

DESIGN ANALYSIS FOR THE DEFENSE HIGH-LEVEL WASTE DISPOSAL CONTAINER

DOE Office of Scientific and Technical Information (OSTI.GOV)

G. Radulesscu; J.S. Tang

The purpose of ''Design Analysis for the Defense High-Level Waste Disposal Container'' analysis is to technically define the defense high-level waste (DHLW) disposal container/waste package using the Waste Package Department's (WPD) design methods, as documented in ''Waste Package Design Methodology Report'' (CRWMS M&O [Civilian Radioactive Waste Management System Management and Operating Contractor] 2000a). The DHLW disposal container is intended for disposal of commercial high-level waste (HLW) and DHLW (including immobilized plutonium waste forms), placed within disposable canisters. The U.S. Department of Energy (DOE)-managed spent nuclear fuel (SNF) in disposable canisters may also be placed in a DHLW disposal container alongmore » with HLW forms. The objective of this analysis is to demonstrate that the DHLW disposal container/waste package satisfies the project requirements, as embodied in Defense High Level Waste Disposal Container System Description Document (SDD) (CRWMS M&O 1999a), and additional criteria, as identified in Waste Package Design Sensitivity Report (CRWMS M&Q 2000b, Table 4). The analysis briefly describes the analytical methods appropriate for the design of the DHLW disposal contained waste package, and summarizes the results of the calculations that illustrate the analytical methods. However, the analysis is limited to the calculations selected for the DHLW disposal container in support of the Site Recommendation (SR) (CRWMS M&O 2000b, Section 7). The scope of this analysis is restricted to the design of the codisposal waste package of the Savannah River Site (SRS) DHLW glass canisters and the Training, Research, Isotopes General Atomics (TRIGA) SNF loaded in a short 18-in.-outer diameter (OD) DOE standardized SNF canister. This waste package is representative of the waste packages that consist of the DHLW disposal container, the DHLW/HLW glass canisters, and the DOE-managed SNF in disposable canisters. The intended use of this analysis

36 CFR 223.86 - Bid restriction on resale of noncompleted contract.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Bid restriction on resale of noncompleted contract. 223.86 Section 223.86 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST BOTANICAL...

36 CFR 223.86 - Bid restriction on resale of noncompleted contract.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Bid restriction on resale of noncompleted contract. 223.86 Section 223.86 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST BOTANICAL...

36 CFR 223.86 - Bid restriction on resale of noncompleted contract.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Bid restriction on resale of noncompleted contract. 223.86 Section 223.86 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST BOTANICAL...

36 CFR 223.86 - Bid restriction on resale of noncompleted contract.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Bid restriction on resale of noncompleted contract. 223.86 Section 223.86 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST BOTANICAL...

SU-F-T-43: Prediction of Dose Increments by Brain Metastases Resection Cavity Shrinkage Model with I-125 and Cs-131 LDR Seed Implantations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Han, D; Braunstein, S; Sneed, P

Purpose: This work aims to determine dose variability via a brain metastases resection cavity shrinkage model (RC-SM) with I-125 or Cs-131 LDR seed implantations. Methods: The RC-SM was developed to represent sequential volume changes of 95 consecutive brain metastases patients. All patients underwent serial surveillance MR and change in cavity volume was recorded for each patient. For the initial resection cavity, a prolate-ellipsoid cavity model was suggested and applied volume shrinkage rates to correspond to 1.7, 3.6, 5.9, 11.7, and 20.5 months after craniotomy. Extra-ring structure (6mm) was added on a surface of the resection volume and the same shrinkagemore » rates were applied. Total 31 LDR seeds were evenly distributed on the surface of the resection cavity. The Amersham 6711 I-125 seed model (Oncura, Arlington Heights, IL) and the Model Cs-1 Rev2 Cs-131 seed model (IsoRay, Richland, WA) were used for TG-43U1 dose calculation and in-house-programed 3D-volumetric dose calculation system was used for resection cavity rigid model (RC-RM) and the RC-SM dose calculation. Results: The initial resection cavity volume shrunk to 25±6%, 35±6.8%, 42±7.7%, 47±9.5%, and 60±11.6%, with respect to sequential MR images post craniotomy, and the shrinkage rate (SR) was calculated as SR=56.41Xexp(−0.2024Xt)+33.99 and R-square value was 0.98. The normal brain dose as assessed via the dose to the ring structure with the RC-SM showed 29.34% and 27.95% higher than the RC-RM, I-125 and Cs-131, respectively. The dose differences between I-125 and Cs-131 seeds within the same models, I-125 cases were 9.17% and 10.35% higher than Cs-131 cases, the RC-RM and the RC-SM, respectively. Conclusion: A realistic RC-SM should be considered during LDR brain seed implementation and post-implement planning to prevent potential overdose. The RC-SM calculation shows that Cs-131 is more advantageous in sparing normal brain as the resection cavity volume changes with the LDR seeds

Geological Disposal of Radioactive Waste: A Long-Term Socio-Technical Experiment.

PubMed

Schröder, Jantine

2016-06-01

In this article we investigate whether long-term radioactive waste management by means of geological disposal can be understood as a social experiment. Geological disposal is a rather particular technology in the way it deals with the analytical and ethical complexities implied by the idea of technological innovation as social experimentation, because it is presented as a technology that ultimately functions without human involvement. We argue that, even when the long term function of the 'social' is foreseen to be restricted to safeguarding the functioning of the 'technical', geological disposal is still a social experiment. In order to better understand this argument and explore how it could be addressed, we elaborate the idea of social experimentation with the notion of co-production and the analytical tools of delegation, prescription and network as developed by actor-network theory. In doing so we emphasize that geological disposal inherently involves relations between surface and subsurface, between humans and nonhumans, between the social, material and natural realm, and that these relations require recognition and further elaboration. In other words, we argue that geological disposal concurrently is a social and a technical experiment, or better, a long-term socio-technical experiment. We end with proposing the idea of 'actor-networking' as a sensitizing concept for future research into what geological disposal as a socio-technical experiment could look like.

Rendering of HDR content on LDR displays: an objective approach

NASA Astrophysics Data System (ADS)

Krasula, Lukáš; Narwaria, Manish; Fliegel, Karel; Le Callet, Patrick

2015-09-01

Dynamic range compression (or tone mapping) of HDR content is an essential step towards rendering it on traditional LDR displays in a meaningful way. This is however non-trivial and one of the reasons is that tone mapping operators (TMOs) usually need content-specific parameters to achieve the said goal. While subjective TMO parameter adjustment is the most accurate, it may not be easily deployable in many practical applications. Its subjective nature can also influence the comparison of different operators. Thus, there is a need for objective TMO parameter selection to automate the rendering process. To that end, we investigate into a new objective method for TMO parameters optimization. Our method is based on quantification of contrast reversal and naturalness. As an important advantage, it does not require any prior knowledge about the input HDR image and works independently on the used TMO. Experimental results using a variety of HDR images and several popular TMOs demonstrate the value of our method in comparison to default TMO parameter settings.

Dealing with electronic waste: modeling the costs and environmental benefits of computer monitor disposal.

PubMed

Macauley, Molly; Palmer, Karen; Shih, Jhih-Shyang

2003-05-01

The importance of information technology to the world economy has brought about a surge in demand for electronic equipment. With rapid technological change, a growing fraction of the increasing stock of many types of electronics becomes obsolete each year. We model the costs and benefits of policies to manage 'e-waste' by focusing on a large component of the electronic waste stream-computer monitors-and the environmental concerns associated with disposal of the lead embodied in cathode ray tubes (CRTs) used in most monitors. We find that the benefits of avoiding health effects associated with CRT disposal appear far outweighed by the costs for a wide range of policies. For the stock of monitors disposed of in the United States in 1998, we find that policies restricting or banning some popular disposal options would increase disposal costs from about US dollar 1 per monitor to between US dollars 3 and US dollars 20 per monitor. Policies to promote a modest amount of recycling of monitor parts, including lead, can be less expensive. In all cases, however, the costs of the policies exceed the value of the avoided health effects of CRT disposal.

10 CFR 61.51 - Disposal site design for land disposal.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Disposal site design for land disposal. 61.51 Section 61.51 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.51 Disposal site design for land...

10 CFR 61.51 - Disposal site design for land disposal.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Disposal site design for land disposal. 61.51 Section 61.51 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.51 Disposal site design for land...

10 CFR 61.51 - Disposal site design for land disposal.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Disposal site design for land disposal. 61.51 Section 61.51 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.51 Disposal site design for land...

10 CFR 61.51 - Disposal site design for land disposal.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Disposal site design for land disposal. 61.51 Section 61.51 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.51 Disposal site design for land...

10 CFR 61.51 - Disposal site design for land disposal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Disposal site design for land disposal. 61.51 Section 61.51 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.51 Disposal site design for land...

Application of PCR-LDR-nucleic acid detection strip in detection of YMDD mutation in hepatitis B patients treated with lamivudine.

PubMed

Xu, Gaolian; You, Qimin; Pickerill, Sam; Zhong, Huayan; Wang, Hongying; Shi, Jian; Luo, Ying; You, Paul; Kong, Huimin; Lu, Fengmin; Hu, Lin

2010-07-01

Chronic hepatitis B virus (CHBV) infection causes cirrhosis and hepatocellular carcinoma. Lamivudine (LAM) has been successfully used to treat CHBV infections but prolonged use leads to the emergence of drug-resistant variants. This is primarily linked to a mutation in the tyrosine-methionine-aspartate-aspartate (YMDD) motif of the HBV polymerase gene at position 204. Rapid diagnosis of drug-resistant HBV is necessary for a prompt treatment response. Common diagnostic methods such as sequencing and restriction fragment length polymorphism (RFLP) analysis lack sensitivity and require significant processing. The aim of this study was to demonstrate the usefulness of a novel diagnostic method that combines polymerase chain reaction (PCR), ligase detection reaction (LDR) and a nucleic acid detection strip (NADS) in detecting site-specific mutations related to HBV LAM resistance. We compared this method (PLNA) to direct sequencing and RFLP analysis in 50 clinical samples from HBV infected patients. There was 90% concordance between all three results. PLNA detected more samples containing mutant variants than both sequencing and RFLP analysis and was more sensitive in detecting mixed variant populations. Plasmid standards indicated that the sensitivity of PLNA is at or below 3,000 copies per ml and that it can detect a minor variant at 5% of the total viral population. This warrants its further development and suggests that the PLNA method could be a useful tool in detecting LAM resistance. (c) 2010 Wiley-Liss, Inc.

The Cancer of the Prostate Risk Assessment (CAPRA) score predicts biochemical recurrence in intermediate-risk prostate cancer treated with external beam radiotherapy (EBRT) dose escalation or low-dose rate (LDR) brachytherapy.

PubMed

Krishnan, Vimal; Delouya, Guila; Bahary, Jean-Paul; Larrivée, Sandra; Taussky, Daniel

2014-12-01

To study the prognostic value of the University of California, San Francisco Cancer of the Prostate Risk Assessment (CAPRA) score to predict biochemical failure (bF) after various doses of external beam radiotherapy (EBRT) and/or permanent seed low-dose rate (LDR) prostate brachytherapy (PB). We retrospectively analysed 345 patients with intermediate-risk prostate cancer, with PSA levels of 10-20 ng/mL and/or Gleason 7 including 244 EBRT patients (70.2-79.2 Gy) and 101 patients treated with LDR PB. The minimum follow-up was 3 years. No patient received primary androgen-deprivation therapy. bF was defined according to the Phoenix definition. Cox regression analysis was used to estimate the differences between CAPRA groups. The overall bF rate was 13% (45/345). The CAPRA score, as a continuous variable, was statistically significant in multivariate analysis for predicting bF (hazard ratio [HR] 1.37, 95% confidence interval [CI] 1.10-1.72, P = 0.006). There was a trend for a lower bF rate in patients treated with LDR PB when compared with those treated by EBRT ≤ 74 Gy (HR 0.234, 95% CI 0.05-1.03, P = 0.055) in multivariate analysis. In the subgroup of patients with a CAPRA score of 3-5, CAPRA remained predictive of bF as a continuous variable (HR 1.51, 95% CI 1.01-2.27, P = 0.047) in multivariate analysis. The CAPRA score is useful for predicting biochemical recurrence in patients treated for intermediate-risk prostate cancer with EBRT or LDR PB. It could help in treatment decisions. © 2013 The Authors. BJU International © 2013 BJU International.

A tool based on Ligation Detection Reaction-Universal Array (LDR-UA) for the characterization of VTEC by identification of virulence-associated and serogroup-specific genes.

PubMed

Lauri, Andrea; Castiglioni, Bianca; Morabito, Stefano; Tozzoli, Rosangela; Consolandi, Clarissa; Mariani, Paola

2011-02-01

Verocytoxigenic Escherichia coli (VTEC) are zoonotic pathogens whose natural reservoir is represented by ruminants, particularly cattle. Infections are mainly acquired by consumption of undercooked contaminated food of animal origin, contact with infected animals and contaminated environment. VTEC O157 is the most frequently isolated serogroup from cases of human disease, however, other VTEC serogroups, such as O26, O111, O145 and O103, are increasingly reported as causing Hemolytic Uremic Syndrome (HUS) worldwide. The identification of VTEC is troublesome, hindering the development of effective prevention strategies. In fact, VTEC are morphologically indistinguishable from harmless E. coli and their pathogenic potential is not strictly dependent on the serogroup, but relies on the presence of a collection of virulence genes. We developed a diagnostic tool for VTEC based on the Ligation Detection Reaction coupled to Universal Array (LDR-UA) for the simultaneous identification of virulence factors and serogroup-associated genes. The method includes the investigation of 40 sites located in 13 fragments from 12 genes (sodCF1/F2, adfO, terB, ehxA, eae, vtx1, vtx2, ihp1, wzx, wbdI, rfbE, dnaK) and was evaluated by performing a trial on a collection of 67 E. coli strains, both VTEC and VT-negative E. coli, as well as on 25 isolates belonging to other related species. Results of this study showed that the LDR-UA technique was specific in identifying the target microorganism. Moreover, due to its higher throughput, the LDR-UA can be a valid and cheaper alternative to real time PCR-based (rt-PCR) methods for VTEC identification. Copyright © 2010 Elsevier Ltd. All rights reserved.

10 CFR 61.50 - Disposal site suitability requirements for land disposal.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Disposal site suitability requirements for land disposal. 61.50 Section 61.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.50 Disposal site...

10 CFR 61.50 - Disposal site suitability requirements for land disposal.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Disposal site suitability requirements for land disposal. 61.50 Section 61.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.50 Disposal site...

10 CFR 61.50 - Disposal site suitability requirements for land disposal.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Disposal site suitability requirements for land disposal. 61.50 Section 61.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.50 Disposal site...

10 CFR 61.50 - Disposal site suitability requirements for land disposal.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Disposal site suitability requirements for land disposal. 61.50 Section 61.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.50 Disposal site...

10 CFR 61.50 - Disposal site suitability requirements for land disposal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Disposal site suitability requirements for land disposal. 61.50 Section 61.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.50 Disposal site...

Disposal methods

NASA Technical Reports Server (NTRS)

Friedlander, Alan

1991-01-01

A number of disposal options for space nuclear reactors and the associated risks, mostly in the long term, based on probabilities of Earth reentry are discussed. The results are based on a five year study that was conducted between 1978 and 1983 on the space disposal of high level nuclear waste. The study provided assessment of disposal options, stability of disposal or storage orbits, and assessment of the long term risks of Earth reentry of the nuclear waste.

Child feces disposal practices in rural Orissa: a cross sectional study.

PubMed

Majorin, Fiona; Freeman, Matthew C; Barnard, Sharmani; Routray, Parimita; Boisson, Sophie; Clasen, Thomas

2014-01-01

An estimated 2.5 billion people worldwide lack access to improved sanitation facilities. While large-scale programs in some countries have increased latrine coverage, they sometimes fail to ensure optimal latrine use, including the safe disposal of child feces, a significant source of exposure to fecal pathogens. We undertook a cross-sectional study to explore fecal disposal practices among children in rural Orissa, India in villages where the Government of India's Total Sanitation Campaign had been implemented at least three years prior to the study. We conducted surveys with heads of 136 households with 145 children under 5 years of age in 20 villages. We describe defecation and feces disposal practices and explore associations between safe disposal and risk factors. Respondents reported that children commonly defecated on the ground, either inside the household (57.5%) for pre-ambulatory children or around the compound (55.2%) for ambulatory children. Twenty percent of pre-ambulatory children used potties and nappies; the same percentage of ambulatory children defecated in a latrine. While 78.6% of study children came from 106 households with a latrine, less than a quarter (22.8%) reported using them for disposal of child feces. Most child feces were deposited with other household waste, both for pre-ambulatory (67.5%) and ambulatory (58.1%) children. After restricting the analysis to households owning a latrine, the use of a nappy or potty was associated with safe disposal of feces (OR 6.72, 95%CI 1.02-44.38) though due to small sample size the regression could not adjust for confounders. In the area surveyed, the Total Sanitation Campaign has not led to high levels of safe disposal of child feces. Further research is needed to identify the actual scope of this potential gap in programming, the health risk presented and interventions to minimize any adverse effect.

Preliminary disposal limits, plume interaction factors, and final disposal limits

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flach, G.

In the 2008 E-Area Performance Assessment (PA), each final disposal limit was constructed as the product of a preliminary disposal limit and a plume interaction factor. The following mathematical development demonstrates that performance objectives are generally expected to be satisfied with high confidence under practical PA scenarios using this method. However, radionuclides that experience significant decay between a disposal unit and the 100-meter boundary, such as H-3 and Sr-90, can challenge performance objectives, depending on the disposed-of waste composition, facility geometry, and the significance of the plume interaction factor. Pros and cons of analyzing single disposal units or multiple disposalmore » units as a group in the preliminary disposal limits analysis are also identified.« less

Disposable versus non-disposable tonometer prisms: a UK national survey

PubMed Central

Jasani, Kirti M; Putri, Christine; Pearl, Amy; Sattar, Nayeem; Mercieca, Karl; Spaeth, George; Bhan-Bhargava, Archana

2017-01-01

Purpose To determine the prevalence of disposable tonometer versus non-disposable tonometer use in the UK and to determine methods of decontamination and frequency of replacement of prisms. A total of 137 ophthalmology departments were interviewed by telephone using a structured questionnaire. The main outcome measured were:types of tonometer prisms used in clinic (disposable, non-disposable and/or other)average disposable prisms used per clinic sessionaverage lifespan of non-disposable prismsprism preference by glaucoma and other teams within department. A cost and benefit analysis was then performed on the data acquired. Results One hundred and fifty-five departments were identified for the survey. Of these, 137 (88.3%) responded. Eighty-one departments (59.1%) used Tonosafe prisms alone, whereas 22 departments (16.1%) used Goldmann non-disposable prisms exclusively. Thirty-five departments (64%) on average have a change rate of 26.5% per year (range: 0–100, median: 20) attributed to damage, loss or theft. Sixteen departments (29%) reported that prisms were used until damaged or lost. Four departments (7%) were uncertain of their prism usage and could not provide further information. Conclusions Majority of eye departments in the UK opt for disposable prisms. This survey shows the perceived cost-effectiveness of disposable prisms is overestimated when the true cost of disinfection and damage is taken into account. Significant cost savings coupled with the low risk of infectivity (if decontaminated properly) should prompt clinicians and ophthalmic departments worldwide to reconsider the use of non-disposable prisms. PMID:29354698

Optical fibre luminescence sensor for real-time LDR brachytherapy dosimetry

NASA Astrophysics Data System (ADS)

Woulfe, P.; O'Keeffe, S.; Sullivan, F. J.

2018-02-01

An optical fibre sensor for monitoring low dose radiation is presented. The sensor is based on a scintillation material embedded within the optical fibre core, which emits visible light when exposed to low level ionising radiation. The incident level of ionising radiation can be determined by analysing the optical emission. An optical fibre sensor is developed, based on radioluminescence whereby radiation sensitive scintillation material, terbium doped gadolinium oxysulphide (Gd2O2S:Tb), is embedded in a cavity of 700μm of a 1mm plastic optical fibre. The sensor is designed for in-vivo monitoring of the radiation dose during radio-active seed implantation for low dose rate (LDR) brachytherapy, in prostate cancer treatment, providing radiation oncologists with real-time information of the radiation dose to the target area and/or nearby organs at risk (OARs). The radiation from the brachytherapy seeds causes emission of visible light from the scintillation material through the process of radioluminescence, which penetrates the fibre, propagating along the optical fibre for remote detection using a multi-pixel photon counter. The sensor demonstrates a high sensitivity to 0.397mCi of Iodine125, the radioactive source most commonly used in brachytherapy for treating prostate cancer.

A BOD monitoring disposable reactor with alginate-entrapped bacteria.

PubMed

Villalobos, Patricio; Acevedo, Cristian A; Albornoz, Fernando; Sánchez, Elizabeth; Valdés, Erika; Galindo, Raúl; Young, Manuel E

2010-10-01

Biochemical oxygen demand (BOD) is a measure of the amount of dissolved oxygen that is required for the biochemical oxidation of the organic compounds in 5 days. New biosensor-based methods have been conducted for a faster determination of BOD. In this study, a mathematical model to evaluate the feasibility of using a BOD sensor, based on disposable alginate-entrapped bacteria, for monitoring BOD in situ was applied. The model considers the influences of alginate bead size and bacterial concentration. The disposable biosensor can be adapted according to specific requirements depending on the organic load contained in the wastewater. Using Klein and Washausen parameter in a Lineweaver-Burk plot, the glucose diffusivity was calculated in 6.4 × 10(-10) (m2/s) for beads of 1 mm in diameter and slight diffusion restrictions were observed (n = 0.85). Experimental results showed a correlation (p < 0.05) between the respirometric peak and the standard BOD test. The biosensor response was representative of BOD.

Evaluation of water-mimicking solid phantom materials for use in HDR and LDR brachytherapy dosimetry

NASA Astrophysics Data System (ADS)

Schoenfeld, Andreas A.; Thieben, Maike; Harder, Dietrich; Poppe, Björn; Chofor, Ndimofor

2017-12-01

In modern HDR or LDR brachytherapy with photon emitters, fast checks of the dose profiles generated in water or a water-equivalent phantom have to be available in the interest of patient safety. However, the commercially available brachytherapy photon sources cover a wide range of photon emission spectra, and the range of the in-phantom photon spectrum is further widened by Compton scattering, so that the achievement of water-mimicking properties of such phantoms involves high requirements on their atomic composition. In order to classify the degree of water equivalence of the numerous commercially available solid water-mimicking phantom materials and the energy ranges of their applicability, the radial profiles of the absorbed dose to water, D w, have been calculated using Monte Carlo simulations in these materials and in water phantoms of the same dimensions. This study includes the HDR therapy sources Nucletron Flexisource Co-60 HDR (60Co), Eckert und Ziegler BEBIG GmbH CSM-11 (137Cs), Implant Sciences Corporation HDR Yb-169 Source 4140 (169Yb) as well as the LDR therapy sources IsoRay Inc. Proxcelan CS-1 (131Cs), IsoAid Advantage I-125 IAI-125A (125I), and IsoAid Advantage Pd-103 IAPd-103A (103Pd). Thereby our previous comparison between phantom materials and water surrounding a Varian GammaMed Plus HDR therapy 192Ir source (Schoenfeld et al 2015) has been complemented. Simulations were performed in cylindrical phantoms consisting of either water or the materials RW1, RW3, Solid Water, HE Solid Water, Virtual Water, Plastic Water DT, Plastic Water LR, Original Plastic Water (2015), Plastic Water (1995), Blue Water, polyethylene, polystyrene and PMMA. While for 192Ir, 137Cs and 60Co most phantom materials can be regarded as water equivalent, for 169Yb the materials Plastic Water LR, Plastic Water DT and RW1 appear as water equivalent. For the low-energy sources 106Pd, 131Cs and 125I, only Plastic Water LR can be classified as water equivalent.

Evaluation of water-mimicking solid phantom materials for use in HDR and LDR brachytherapy dosimetry.

PubMed

Schoenfeld, Andreas A; Thieben, Maike; Harder, Dietrich; Poppe, Björn; Chofor, Ndimofor

2017-11-21

In modern HDR or LDR brachytherapy with photon emitters, fast checks of the dose profiles generated in water or a water-equivalent phantom have to be available in the interest of patient safety. However, the commercially available brachytherapy photon sources cover a wide range of photon emission spectra, and the range of the in-phantom photon spectrum is further widened by Compton scattering, so that the achievement of water-mimicking properties of such phantoms involves high requirements on their atomic composition. In order to classify the degree of water equivalence of the numerous commercially available solid water-mimicking phantom materials and the energy ranges of their applicability, the radial profiles of the absorbed dose to water, D w , have been calculated using Monte Carlo simulations in these materials and in water phantoms of the same dimensions. This study includes the HDR therapy sources Nucletron Flexisource Co-60 HDR ( 60 Co), Eckert und Ziegler BEBIG GmbH CSM-11 ( 137 Cs), Implant Sciences Corporation HDR Yb-169 Source 4140 ( 169 Yb) as well as the LDR therapy sources IsoRay Inc. Proxcelan CS-1 ( 131 Cs), IsoAid Advantage I-125 IAI-125A ( 125 I), and IsoAid Advantage Pd-103 IAPd-103A ( 103 Pd). Thereby our previous comparison between phantom materials and water surrounding a Varian GammaMed Plus HDR therapy 192 Ir source (Schoenfeld et al 2015) has been complemented. Simulations were performed in cylindrical phantoms consisting of either water or the materials RW1, RW3, Solid Water, HE Solid Water, Virtual Water, Plastic Water DT, Plastic Water LR, Original Plastic Water (2015), Plastic Water (1995), Blue Water, polyethylene, polystyrene and PMMA. While for 192 Ir, 137 Cs and 60 Co most phantom materials can be regarded as water equivalent, for 169 Yb the materials Plastic Water LR, Plastic Water DT and RW1 appear as water equivalent. For the low-energy sources 106 Pd, 131 Cs and 125 I, only Plastic Water LR can be classified as water

Time-driven activity-based costing of low-dose-rate and high-dose-rate brachytherapy for low-risk prostate cancer.

PubMed

Ilg, Annette M; Laviana, Aaron A; Kamrava, Mitchell; Veruttipong, Darlene; Steinberg, Michael; Park, Sang-June; Burke, Michael A; Niedzwiecki, Douglas; Kupelian, Patrick A; Saigal, Christopher

Cost estimates through traditional hospital accounting systems are often arbitrary and ambiguous. We used time-driven activity-based costing (TDABC) to determine the true cost of low-dose-rate (LDR) and high-dose-rate (HDR) brachytherapy for prostate cancer and demonstrate opportunities for cost containment at an academic referral center. We implemented TDABC for patients treated with I-125, preplanned LDR and computed tomography based HDR brachytherapy with two implants from initial consultation through 12-month followup. We constructed detailed process maps for provision of both HDR and LDR. Personnel, space, equipment, and material costs of each step were identified and used to derive capacity cost rates, defined as price per minute. Each capacity cost rate was then multiplied by the relevant process time and products were summed to determine total cost of care. The calculated cost to deliver HDR was greater than LDR by $2,668.86 ($9,538 vs. $6,869). The first and second HDR treatment day cost $3,999.67 and $3,955.67, whereas LDR was delivered on one treatment day and cost $3,887.55. The greatest overall cost driver for both LDR and HDR was personnel at 65.6% ($4,506.82) and 67.0% ($6,387.27) of the total cost. After personnel costs, disposable materials contributed the second most for LDR ($1,920.66, 28.0%) and for HDR ($2,295.94, 24.0%). With TDABC, the true costs to deliver LDR and HDR from the health system perspective were derived. Analysis by physicians and hospital administrators regarding the cost of care afforded redesign opportunities including delivering HDR as one implant. Our work underscores the need to assess clinical outcomes to understand the true difference in value between these modalities. Copyright © 2016 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

Reducing Liver Fat by Low Carbohydrate Caloric Restriction Targets Hepatic Glucose Production in Non-Diabetic Obese Adults with Non-Alcoholic Fatty Liver Disease.

PubMed

Yu, Haoyong; Jia, Weiping; Guo, ZengKui

2014-09-01

Non-alcoholic fatty liver disease (NAFLD) impairs liver functions, the organ responsible for the regulation of endogenous glucose production and thus plays a key role in glycemic homeostasis. Therefore, interventions designed to normalize liver fat content are needed to improve glucose metabolism in patients affected by NAFLD such as obesity. this investigation is designed to determine the effects of caloric restriction on hepatic and peripheral glucose metabolism in obese humans with NAFLD. eight non-diabetic obese adults were restricted for daily energy intake (800 kcal) and low carbohydrate (<10%) for 8 weeks. Body compositions, liver fat and hepatic glucose production (HGP) and peripheral glucose disposal before and after the intervention were determined. the caloric restriction reduced liver fat content by 2/3 (p = 0.004). Abdominal subcutaneous and visceral fat, body weight, BMI, waist circumference and fasting plasma triglyceride and free fatty acid concentrations all significantly decreased (p < 0.05). The suppression of post-load HGP was improved by 22% (p = 0.002) whereas glucose disposal was not affected (p = 0.3). Fasting glucose remained unchanged and the changes in the 2-hour plasma glucose and insulin concentration were modest and statistically insignificant (p > 0.05). Liver fat is the only independent variable highly correlated to HGP after the removal of confounders. NAFLD impairs HGP but not peripheral glucose disposal; low carbohydrate caloric restriction effectively lowers liver fat which appears to directly correct the HGP impairment.

Using LDR as Sensing Element for an External Fuzzy Controller Applied in Photovoltaic Pumping Systems with Variable-Speed Drives

PubMed Central

Maranhão, Geraldo Neves De A.; Brito, Alaan Ubaiara; Leal, Anderson Marques; Fonseca, Jéssica Kelly Silva; Macêdo, Wilson Negrão

2015-01-01

In the present paper, a fuzzy controller applied to a Variable-Speed Drive (VSD) for use in Photovoltaic Pumping Systems (PVPS) is proposed. The fuzzy logic system (FLS) used is embedded in a microcontroller and corresponds to a proportional-derivative controller. A Light-Dependent Resistor (LDR) is used to measure, approximately, the irradiance incident on the PV array. Experimental tests are executed using an Arduino board. The experimental results show that the fuzzy controller is capable of operating the system continuously throughout the day and controlling the direct current (DC) voltage level in the VSD with a good performance. PMID:26402688

Using LDR as Sensing Element for an External Fuzzy Controller Applied in Photovoltaic Pumping Systems with Variable-Speed Drives.

PubMed

Maranhão, Geraldo Neves De A; Brito, Alaan Ubaiara; Leal, Anderson Marques; Fonseca, Jéssica Kelly Silva; Macêdo, Wilson Negrão

2015-09-22

In the present paper, a fuzzy controller applied to a Variable-Speed Drive (VSD) for use in Photovoltaic Pumping Systems (PVPS) is proposed. The fuzzy logic system (FLS) used is embedded in a microcontroller and corresponds to a proportional-derivative controller. A Light-Dependent Resistor (LDR) is used to measure, approximately, the irradiance incident on the PV array. Experimental tests are executed using an Arduino board. The experimental results show that the fuzzy controller is capable of operating the system continuously throughout the day and controlling the direct current (DC) voltage level in the VSD with a good performance.

Some less conventional options for plutonium disposal

NASA Astrophysics Data System (ADS)

Stoll, Dr. Wolfgang, Prof.

2000-07-01

Disposition of weapons Pu (W-Pu) aims at the replacement of military access restrictions by inherent longlasting technical barriers to make the return into the weapons state difficult and not rewarding anymore. At the time of the NAS-study in 1994, two ways were perceived to be mature and selected: Fissioning of W-Pu as LWR-MOX and the disposal in a vitrified radionuclide-spiked form.1 Both options since have been questioned for equality, met different acceptance at both superpowers and showed slow progress. A criterion to measure disarmament would be the amount of W-Pu in the different proliferation resistant forms, multiplied by the effort needed for each form to return to weapons quality.

7 CFR 319.37 - Prohibitions and restrictions on importation; disposal of articles refused importation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... of articles refused importation. (a) No person shall import or offer for entry into the United States... person shall import or offer for entry into the United States any restricted article except in accordance... Form 523), destroy, ship to a point outside the United States, or apply treatments or other safeguards...

Child Feces Disposal Practices in Rural Orissa: A Cross Sectional Study

PubMed Central

Majorin, Fiona; Freeman, Matthew C.; Barnard, Sharmani; Routray, Parimita; Boisson, Sophie; Clasen, Thomas

2014-01-01

Background An estimated 2.5 billion people worldwide lack access to improved sanitation facilities. While large-scale programs in some countries have increased latrine coverage, they sometimes fail to ensure optimal latrine use, including the safe disposal of child feces, a significant source of exposure to fecal pathogens. We undertook a cross-sectional study to explore fecal disposal practices among children in rural Orissa, India in villages where the Government of India's Total Sanitation Campaign had been implemented at least three years prior to the study. Methods and Findings We conducted surveys with heads of 136 households with 145 children under 5 years of age in 20 villages. We describe defecation and feces disposal practices and explore associations between safe disposal and risk factors. Respondents reported that children commonly defecated on the ground, either inside the household (57.5%) for pre-ambulatory children or around the compound (55.2%) for ambulatory children. Twenty percent of pre-ambulatory children used potties and nappies; the same percentage of ambulatory children defecated in a latrine. While 78.6% of study children came from 106 households with a latrine, less than a quarter (22.8%) reported using them for disposal of child feces. Most child feces were deposited with other household waste, both for pre-ambulatory (67.5%) and ambulatory (58.1%) children. After restricting the analysis to households owning a latrine, the use of a nappy or potty was associated with safe disposal of feces (OR 6.72, 95%CI 1.02–44.38) though due to small sample size the regression could not adjust for confounders. Conclusions In the area surveyed, the Total Sanitation Campaign has not led to high levels of safe disposal of child feces. Further research is needed to identify the actual scope of this potential gap in programming, the health risk presented and interventions to minimize any adverse effect. PMID:24586864

7 CFR 319.37 - Prohibitions and restrictions on importation; disposal of articles refused importation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... articles refused importation. (a) No person shall import or offer for entry into the United States any... import or offer for entry into the United States any restricted article except in accordance with this...), destroy, ship to a point outside the United States, or apply treatments or other safeguards to the article...

7 CFR 319.37 - Prohibitions and restrictions on importation; disposal of articles refused importation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... articles refused importation. (a) No person shall import or offer for entry into the United States any... import or offer for entry into the United States any restricted article except in accordance with this...), destroy, ship to a point outside the United States, or apply treatments or other safeguards to the article...

In-vivo laser induced urethral stricture animal model for investigating the potential of LDR-brachytherapy

NASA Astrophysics Data System (ADS)

Sroka, Ronald; Lellig, Katja; Bader, Markus; Stief, Christian; Weidlich, Patrick; Wechsel, G.; Assmann, Walter; Becker, R.; Fedorova, O.; Khoder, Wael

2015-02-01

Purpose: Treatment of urethral strictures is a major challenge in urology. For investigation of different treatment methods an animal model was developed by reproducible induction of urethral strictures in rabbits to mimic the human clinical situation. By means of this model the potential of endoluminal LDR brachytherapy using β-irradiation as prophylaxis of recurrent urethral strictures investigated. Material and Methods: A circumferential urethral stricture was induced by energy deposition using laser light application (wavelength λ=1470 nm, 10 W, 10 s, applied energy 100 J) in the posterior urethra of anaesthetized New Zealand White male rabbits. The radial light emitting fiber was introduced by means of a children resectoscope (14F). The grade of urethral stricture was evaluated in 18 rabbits using videourethroscopy and urethrography at day 28 after stricture induction. An innovative catheter was developed based on a β-irradiation emitting foil containing 32P, which was wrapped around the application system. Two main groups (each n=18) were separated. The "internal urethrotomy group" received after 28days of stricture induction immediately after surgical urethrotomy of the stricture the radioactive catheter for one week in a randomized, controlled and blinded manner. There were 3 subgroups with 6 animals each receiving 0 Gy, 15 Gy and 30 Gy. In contrast animals from the "De Nuovo group" received directly after the stricture induction (day 0) the radioactive catheter also for the duration of one week divided into the same dose subgroups. In order to determine the radiation tolerance of the urethral mucosa, additional animals without any stricture induction received a radioactive catheter applying a total dose of 30 Gy (n=2) and 15 Gy (n=1). Cystourethrography and endoscopic examination of urethra were performed on all operation days for monitoring treatment progress. Based on these investigation a classification of the stricture size was performed and

Methods for prostate stabilization during transperineal LDR brachytherapy.

PubMed

Podder, Tarun; Sherman, Jason; Rubens, Deborah; Messing, Edward; Strang, John; Ng, Wan-Sing; Yu, Yan

2008-03-21

In traditional prostate brachytherapy procedures for a low-dose-rate (LDR) radiation seed implant, stabilizing needles are first inserted to provide some rigidity and support to the prostate. Ideally this will provide better seed placement and an overall improved treatment. However, there is much speculation regarding the effectiveness of using regular brachytherapy needles as stabilizers. In this study, we explored the efficacy of two types of needle geometries (regular brachytherapy needle and hooked needle) and several clinically feasible configurations of the stabilization needles. To understand and assess the prostate movement during seed implantation, we collected in vivo data from patients during actual brachytherapy procedures. In vitro experimentation with tissue-equivalent phantoms allowed us to further understand the mechanics behind prostate stabilization. We observed superior stabilization with the hooked needles compared to the regular brachytherapy needles (more than 40% in bilateral parallel needle configuration). Prostate movement was also reduced significantly when regular brachytherapy needles were in an angulated configuration as compared to the parallel configuration (more than 60%). When the hooked needles were angulated for stabilization, further reduction in prostate displacement was observed. In general, for convenience of dosimetric planning and to avoid needle collision, all needles are desired to be in a parallel configuration. In this configuration, hooked needles provide improved stabilization of the prostate. On the other hand, both regular and hooked needles appear to be equally effective in reducing prostate movement when they are in angulated configurations, which will be useful in seed implantation using a robotic system. We have developed nonlinear spring-damper model for the prostate movement which can be used for adapting dosimetric planning during brachytherapy as well as for developing more realistic haptic devices and

77 FR 50622 - Land Disposal Restrictions: Site-Specific Treatment Variance for Hazardous Selenium-Bearing Waste...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-22

... Restrictions: Site-Specific Treatment Variance for Hazardous Selenium-Bearing Waste Treated by U.S. Ecology... program, to U.S. Ecology Nevada in Beatty, Nevada for the treatment of a hazardous selenium- bearing waste.... Ecology Nevada located in Beatty, Nevada. B. Table of Contents I. Background [[Page 50623

Ocean Disposal Site Monitoring

EPA Pesticide Factsheets

EPA is responsible for managing all designated ocean disposal sites. Surveys are conducted to identify appropriate locations for ocean disposal sites and to monitor the impacts of regulated dumping at the disposal sites.

76 FR 30027 - Land Disposal Restrictions: Site-Specific Treatment Variance for Hazardous Selenium-Bearing Waste...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... Restrictions: Site-Specific Treatment Variance for Hazardous Selenium-Bearing Waste Treated by U.S. Ecology.... Ecology Nevada in Beatty, Nevada and withdrew an existing site- specific treatment variance issued to... 268.44(o)) by granting a site-specific treatment variance to U.S. Ecology Nevada in Beatty, Nevada and...

Development of an adjoint sensitivity field-based treatment-planning technique for the use of newly designed directional LDR sources in brachytherapy.

PubMed

Chaswal, V; Thomadsen, B R; Henderson, D L

2012-02-21

The development and application of an automated 3D greedy heuristic (GH) optimization algorithm utilizing the adjoint sensitivity fields for treatment planning to assess the advantage of directional interstitial prostate brachytherapy is presented. Directional and isotropic dose kernels generated using Monte Carlo simulations based on Best Industries model 2301 I-125 source are utilized for treatment planning. The newly developed GH algorithm is employed for optimization of the treatment plans for seven interstitial prostate brachytherapy cases using mixed sources (directional brachytherapy) and using only isotropic sources (conventional brachytherapy). All treatment plans resulted in V100 > 98% and D90 > 45 Gy for the target prostate region. For the urethra region, the D10(Ur), D90(Ur) and V150(Ur) and for the rectum region the V100cc, D2cc, D90(Re) and V90(Re) all are reduced significantly when mixed sources brachytherapy is used employing directional sources. The simulations demonstrated that the use of directional sources in the low dose-rate (LDR) brachytherapy of the prostate clearly benefits in sparing the urethra and the rectum sensitive structures from overdose. The time taken for a conventional treatment plan is less than three seconds, while the time taken for a mixed source treatment plan is less than nine seconds, as tested on an Intel Core2 Duo 2.2 GHz processor with 1GB RAM. The new 3D GH algorithm is successful in generating a feasible LDR brachytherapy treatment planning solution with an extra degree of freedom, i.e. directionality in very little time.

Development of an adjoint sensitivity field-based treatment-planning technique for the use of newly designed directional LDR sources in brachytherapy

NASA Astrophysics Data System (ADS)

Chaswal, V.; Thomadsen, B. R.; Henderson, D. L.

2012-02-01

The development and application of an automated 3D greedy heuristic (GH) optimization algorithm utilizing the adjoint sensitivity fields for treatment planning to assess the advantage of directional interstitial prostate brachytherapy is presented. Directional and isotropic dose kernels generated using Monte Carlo simulations based on Best Industries model 2301 I-125 source are utilized for treatment planning. The newly developed GH algorithm is employed for optimization of the treatment plans for seven interstitial prostate brachytherapy cases using mixed sources (directional brachytherapy) and using only isotropic sources (conventional brachytherapy). All treatment plans resulted in V100 > 98% and D90 > 45 Gy for the target prostate region. For the urethra region, the D10Ur, D90Ur and V150Ur and for the rectum region the V100cc, D2cc, D90Re and V90Re all are reduced significantly when mixed sources brachytherapy is used employing directional sources. The simulations demonstrated that the use of directional sources in the low dose-rate (LDR) brachytherapy of the prostate clearly benefits in sparing the urethra and the rectum sensitive structures from overdose. The time taken for a conventional treatment plan is less than three seconds, while the time taken for a mixed source treatment plan is less than nine seconds, as tested on an Intel Core2 Duo 2.2 GHz processor with 1GB RAM. The new 3D GH algorithm is successful in generating a feasible LDR brachytherapy treatment planning solution with an extra degree of freedom, i.e. directionality in very little time.

Assessment of the disposal of radioactive petroleum industry waste in nonhazardous landfills using risk-based modeling.

PubMed

Smith, Karen P; Arnish, John J; Williams, Gustavious P; Blunt, Deborah L

2003-05-15

Certain petroleum production activities cause naturally occurring radioactive materials (NORM) to accumulate in concentrations above natural background levels, making safe and cost-effective management of such technologically enhanced NORM (TENORM) a key issue for the petroleum industry. As a result, both industry and regulators are interested in identifying cost-effective disposal alternatives that provide adequate protection of human health and the environment One such alternative, currently allowed in Michigan with restrictions, is the disposal of TENORM wastes in nonhazardous waste landfills. The disposal of petroleum industry wastes containing radium-226 (Ra-226) in nonhazardous landfills was modeled to evaluate the potential radiological doses and health risks to workers and the public. Multiple scenarios were considered in evaluating the potential risks associated with landfill operations and the future use of the property. The scenarios were defined, in part, to evaluate the Michigan policy; sensitivity analyses were conducted to evaluate the impact of key parameters on potential risks. The results indicate that the disposal of petroleum industry TENORM wastes in nonhazardous landfills in accordance with the Michigan policy and existing landfill regulations presents a negligible risk to most of the potential receptors considered in this study.

A temporal and spatial assessment of TBT concentrations at dredged material disposal sites around the coast of England and Wales.

PubMed

Bolam, Thi; Barry, Jon; Law, Robin J; James, David; Thomas, Boby; Bolam, Stefan G

2014-02-15

Despite legislative interventions since the 1980s, contemporary concentrations of organotin compounds in marine sediments still impose restrictions on the disposal of dredged material in the UK. Here, we analyse temporal and spatial data to assess the effectiveness of the ban on the use of TBT paints in reducing concentrations at disposal sites. At a national scale, there was a statistically significant increase in the proportion of samples in which the concentration was below the limit of detection (LOD) from 1998 to 2010. This was observed for sediments both inside and outside the disposal sites. However, this temporal decline in organotin concentration is disposal site-specific. Of the four sites studied in detail, two displayed significant increases in proportion of samples below LOD over time. We argue that site-specificity in the effectiveness of the TBT ban results from variations in historical practices at source and unique environmental characteristics of each site. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

High-throughput multiplex HLA-typing by ligase detection reaction (LDR) and universal array (UA) approach.

PubMed

Consolandi, Clarissa

2009-01-01

One major goal of genetic research is to understand the role of genetic variation in living systems. In humans, by far the most common type of such variation involves differences in single DNA nucleotides, and is thus termed single nucleotide polymorphism (SNP). The need for improvement in throughput and reliability of traditional techniques makes it necessary to develop new technologies. Thus the past few years have witnessed an extraordinary surge of interest in DNA microarray technology. This new technology offers the first great hope for providing a systematic way to explore the genome. It permits a very rapid analysis of thousands genes for the purpose of gene discovery, sequencing, mapping, expression, and polymorphism detection. We generated a series of analytical tools to address the manufacturing, detection and data analysis components of a microarray experiment. In particular, we set up a universal array approach in combination with a PCR-LDR (polymerase chain reaction-ligation detection reaction) strategy for allele identification in the HLA gene.

Space disposal of nuclear wastes

NASA Technical Reports Server (NTRS)

Priest, C. C.; Nixon, R. F.; Rice, E. E.

1980-01-01

The DOE has been studying several options for nuclear waste disposal, among them space disposal, which NASA has been assessing. Attention is given to space disposal destinations noting that a circular heliocentric orbit about halfway between Earth and Venus is the reference option in space disposal studies. Discussion also covers the waste form, showing that parameters to be considered include high waste loading, high thermal conductivity, thermochemical stability, resistance to leaching, fabrication, resistance to oxidation and to thermal shock. Finally, the Space Shuttle nuclear waste disposal mission profile is presented.

Disposal of Vessels at Sea

EPA Pesticide Factsheets

Vessel disposal general permits are issued by the EPA under the Marine Protection, Research and Sanctuaries Act. Information is provided for vessel disposal permit applicants and where to dispose a vessel.

Subsurface waste disposal by means of wells - A selective annotated bibliography

USGS Publications Warehouse

Rima, Donald Robert; Chase, Edith B.; Myers, Beverly M.

1971-01-01

Subsurface waste disposal by means of wells is the practice of using drilled wells to inject unwanted substances into underground rock formations. The use of wells for this purpose is not a new idea. As long ago as the end of the last century, it was common practice to drill wells for the express purpose of draining swamps and small lakes to reclaim the land for agricultural purposes. A few decades later in the 1920's and 1930's many oil companies began using injection wells to dispose of oil-field brines and to repressurize oil reservoirs. During World War II, the Atomic Energy Commission began using injection wells to dispose of certain types of radioactive wastes. More recently, injection wells have been drilled to dispose of a variety of byproducts of industrial processes. The number of such wells has increased rapidly since Congress passed the Clean Streams Act of 1966, which restricted the discharge of waste into surface waters.Many scientists and public officials question the propriety of using the term "disposal" when referring to the underground injection of wastes. Their reasons are that underground injection is not, as many advocates claim, "a complete and final answer" to the waste-disposal problem. Rather, it is merely a process wherein the injected wastes are committed to the subsurface with uncertainty as to their ultimate fate or limits of confinement. In effect, the wastes, undiminished and unchanged, are removed from the custody of man and placed in the custody of nature.Although the concept of waste-injection wells is relatively simple, the effects of waste injection can be very complex, particularly when dealing with the exotic and complex components of some industrial wastes. Besides the physical forces of injection, there are many varied interactions between the injected wastes and the materials within the injection zone. Because these changes occur out of sight in the subsurface, they are difficult to assess and not generally understood. In

Special Analysis: Disposal of ETF Activated Carbon Vessels in Slit Trenches at the E-Area Low-Level Waste Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Collard, L.B.

2003-08-25

This Special Analysis (SA) addresses two contaminants of concern, H-3 and I-129, in three Effluent Treatment Facility (ETF) Activated Carbon Vessels awaiting disposal as solid waste. The Unreviewed Disposal Question (UDQ) evaluation listed two options for disposal of this waste, disposal as Components-in-Grout (CIG) or disposal in Slit Trenches with sealed openings to restrict release of H-3 form the vessels. Consumption of the CIG inventory limit and consumption of CIG facility volume are shown for the ETF vessels to allow easy comparison with the consumption of Slit Trench inventory limit and consumption of the Slit Trench facility volume . Themore » inventory projections are based on doubling the inventory of the three ETF vessels in the E-Area to account for the unknown inventory of three ETF vessels in the ETF. When the grout ultimately is assumed to degrade hydraulically, the water movement is not impeded as much as the release is accelerated by the presence of the grout. Under these conditions for the CIG trenches relative to the Slit Trenches, the well concentrations are higher, the inventory limit is lower and for a given inventory the inventory limit consumption is higher.« less

WE-DE-201-04: Cross Validation of Knowledge-Based Treatment Planning for Prostate LDR Brachytherapy Using Principle Component Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roper, J; Ghavidel, B; Godette, K

Purpose: To validate a knowledge-based algorithm for prostate LDR brachytherapy treatment planning. Methods: A dataset of 100 cases was compiled from an active prostate seed implant service. Cases were randomized into 10 subsets. For each subset, the 90 remaining library cases were registered to a common reference frame and then characterized on a point by point basis using principle component analysis (PCA). Each test case was converted to PCA vectors using the same process and compared with each library case using a Mahalanobis distance to evaluate similarity. Rank order PCA scores were used to select the best-matched library case. Themore » seed arrangement was extracted from the best-matched case and used as a starting point for planning the test case. Any subsequent modifications were recorded that required input from a treatment planner to achieve V100>95%, V150<60%, V200<20%. To simulate operating-room planning constraints, seed activity was held constant, and the seed count could not increase. Results: The computational time required to register test-case contours and evaluate PCA similarity across the library was 10s. Preliminary analysis of 2 subsets shows that 9 of 20 test cases did not require any seed modifications to obtain an acceptable plan. Five test cases required fewer than 10 seed modifications or a grid shift. Another 5 test cases required approximately 20 seed modifications. An acceptable plan was not achieved for 1 outlier, which was substantially larger than its best match. Modifications took between 5s and 6min. Conclusion: A knowledge-based treatment planning algorithm for prostate LDR brachytherapy is being cross validated using 100 prior cases. Preliminary results suggest that for this size library, acceptable plans can be achieved without planner input in about half of the cases while varying amounts of planner input are needed in remaining cases. Computational time and planning time are compatible with clinical practice.« less

SU-F-19A-11: Retrospective Evaluation of Thermal Coverage by Thermobrachytherapy Seed Arrangements of Clinical LDR Prostate Implants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Warrell, G; Shvydka, D; Chen, C

Purpose: The superiority of a properly-administered combination of radiation therapy and hyperthermia over radiation alone in treatment of human cancers has been demonstrated in multiple studies examining radiobiology, local control, and survival. Unfortunately, hyperthermia is not yet a common modality in oncology practice, due in part to the technical difficulty of heating a deep-seated target volume to sufficient temperature. To address this problem, our group has invented a thermobrachytherapy (TB) seed based on a commonly-used low dose-rate permanent brachytherapy seed for implant in solid tumors. Instead of the tungsten radiographic marker of the standard seed, the TB seed contains onemore » of a self-regulating ferromagnetic alloy. Placement of a patient implanted with such seeds in an oscillating magnetic field generates heat via induction of eddy currents. We present the results of studies of the capability of clinically-realistic TB seed arrangements to adequately heat defined target volumes. Methods: Seed distributions for several past LDR prostate permanent implant brachytherapy patients were reproduced in the finite element analysis software package COMSOL Multiphysics 4.4, with the difference that TB seeds were modelled, rather than the radiation-only seeds actually used for their treatments. The implant geometries were mainly of the modified peripheral loading type; a range of prostatic volumes and blood perfusion rates likely to be seen in a clinical setting were examined. Results: According to the simulations, when distributed to optimize radiation dose, TB seeds also produce sufficient heat to provide thermal coverage of the target given proper selection of the magnetic field strength. However, the thermal distributions may be improved by additional use of hyperthermia-only seeds. Conclusion: A dual-modality seed intended as an alternative to and using the same implantation apparatus and technique as the standard LDR permanent implant seed has

41 CFR 102-75.280 - What information concerning a proposed disposal must a disposal agency provide to the Attorney...

Code of Federal Regulations, 2010 CFR

2010-07-01

... concerning a proposed disposal must a disposal agency provide to the Attorney General to determine the... information concerning a proposed disposal must a disposal agency provide to the Attorney General to determine the applicability of antitrust laws? The disposal agency must promptly provide the Attorney General...

Two-phase anaerobic digestion of partially acidified sewage sludge: a pilot plant study for safe sludge disposal in developing countries.

PubMed

Passio, Luca; Rizzoa, Luigi; Fuchs, Stephan

2012-09-01

The unsafe disposal of wastewater and sludge in different areas of developing countries results in significant environmental pollution, particularly for groundwater, thus increasing the risk of waterborne diseases spreading. In this work, a two-phase anaerobic digestion process for post-treatment of partially acidified sewage sludge was investigated to evaluate its feasibility as a safe sludge disposal system. Pilot tests showed that an effective sludge stabilization can be achieved (total volatile solids content <65%, organic acid concentration <200 mg/L at flow rate = 50 L/d and hydraulic residence time = 18 d) as well as a relative low faecal coliform density (<1000 most probable number per g total solids), showing that land application of the sludge without restrictions is possible according to US Environmental Protection Agency criteria for safe sludge disposal. A biogas production as high as 390 L/d with a 60% methane content by volume was achieved, showing that energy production from biogas may be achieved as well.

40 CFR 761.218 - Certificate of disposal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest, the... certifying the fact of disposal of the identified PCB waste, including the date(s) of disposal, and...

40 CFR 761.218 - Certificate of disposal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest, the... certifying the fact of disposal of the identified PCB waste, including the date(s) of disposal, and...

40 CFR 761.218 - Certificate of disposal.

Code of Federal Regulations, 2012 CFR

2012-07-01

... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest, the... certifying the fact of disposal of the identified PCB waste, including the date(s) of disposal, and...

40 CFR 761.218 - Certificate of disposal.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest, the... certifying the fact of disposal of the identified PCB waste, including the date(s) of disposal, and...

40 CFR 761.218 - Certificate of disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest, the owner or operator of the disposal facility shall prepare a Certificate of Disposal for the PCBs and PCB...

DOSE ASSESSMENTS FROM THE DISPOSAL OF LOW ...

EPA Pesticide Factsheets

Modeling the long-term performance of the RCRA-C disposal cell and potential doses to off-site receptors is used to derive maximum radionuclide specific concentrations in the wastes that would enable these wastes to be disposed of safely using the RCRA-C disposal cell technology. Modeling potential exposures to derive these waste acceptance concentrations involves modeling exposures to workers during storage, treatment and disposal of the wastes, as well as exposures to individuals after disposal operations have ceased. Post facility closure exposures can result from the slow expected degradation of the disposal cell over long time periods (one thousand years after disposal) and in advertent human intrusion. Provide a means of determining waste acceptance radionuclide concentrations for disposal of debris from radiological dispersal device incidents as well as low-activity wastes generated in commercial, medical and research activities, potentially serve as the technical basis for guidance on disposal of these materials.

48 CFR 945.604-1 - Disposal methods.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Disposal methods. 945.604... GOVERNMENT PROPERTY Reporting, Reutilization, and Disposal 945.604-1 Disposal methods. (b)(3) Recovering...) See 945.670 for DOE disposal methods. ...

48 CFR 945.604-1 - Disposal methods.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Disposal methods. 945.604... GOVERNMENT PROPERTY Reporting, Reutilization, and Disposal 945.604-1 Disposal methods. (b)(3) Recovering...) See 945.670 for DOE disposal methods. ...

Application for a Permit to Operate a Class III Solid Waste Disposal Site at the Nevada National Security Site Area 5 Asbestiform Low-Level Solid Waste Disposal Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

NSTec Environmental Programs

2010-10-04

The Nevada National Security Site (NNSS) is located approximately 105 km (65 mi) northwest of Las Vegas, Nevada. The U.S. Department of Energy National Nuclear Security Administration Nevada Site Office (NNSA/NSO) is the federal lands management authority for the NNSS and National Security Technologies, LLC (NSTec) is the Management and Operations contractor. Access on and off the NNSS is tightly controlled, restricted, and guarded on a 24-hour basis. The NNSS is posted with signs along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NNSS. The Area 5 Radioactive Waste Management Site (RWMS) ismore » the location of the permitted facility for the Solid Waste Disposal Site (SWDS). The Area 5 RWMS is located near the eastern edge of the NNSS (Figure 1), approximately 26 km (16 mi) north of Mercury, Nevada. The Area 5 RWMS is used for the disposal of low-level waste (LLW) and mixed low-level waste. Many areas surrounding the RWMS have been used in conducting nuclear tests. The site will be used for the disposal of regulated Asbestiform Low-Level Waste (ALLW), small quantities of low-level radioactive hydrocarbon-burdened (LLHB) media and debris, LLW, LLW that contains Polychlorinated Biphenyl (PCB) Bulk Product Waste greater than 50 ppm that leaches at a rate of less than 10 micrograms of PCB per liter of water, and small quantities of LLHB demolition and construction waste (hereafter called permissible waste). Waste containing free liquids, or waste that is regulated as hazardous waste under the Resource Conservation and Recovery Act (RCRA) or state-of-generation hazardous waste regulations, will not be accepted for disposal at the site. Waste regulated under the Toxic Substances Control Act (TSCA) that will be accepted at the disposal site is regulated asbestos-containing materials (RACM) and PCB Bulk Product Waste greater than 50 ppm that leaches at a rate of less than 10 micrograms of PCB per liter of water. The term

Changes in glucose disposal after a caloric restriction-induced weight loss program in obese postmenopausal women: characteristics of positive and negative responders in a Montreal-Ottawa New Emerging Team study.

PubMed

Myette-Côté, Étienne; Doucet, Éric; Prud'homme, Denis; Rabasa-Lhoret, Rémi; Lavoie, Jean-Marc; Brochu, Martin

2015-01-01

This study aims to investigate individual characteristics that explain interindividual variations in glucose disposal in response to a 6-month weight loss program in obese postmenopausal women. The cohort was divided into tertiles based on changes in glucose disposal after weight loss. Only women in the upper tertile (positive responders: Δ glucose disposal ≥ 0.92 mg/kg/min; n = 19) and lower tertile (negative responders: Δ glucose disposal ≤ -0.23 mg/kg/min; n = 19) were considered for analyses. Outcome measures included body weight, lean body mass (LBM), LBM index (= LBM / height [m]), fat mass (FM), FM index (= FM / height [m]), visceral fat, subcutaneous abdominal fat, high-sensitivity C-reactive protein (hsCRP) levels, interleukin-6, lipid profile, physical activity levels, fasting blood glucose and insulin levels, glucose disposal by hyperinsulinemic-euglycemic clamp technique, and resting blood pressure. At baseline, positive responders had higher triglycerides and hsCRP levels and lower glucose disposal (0.01 < P < 0.05) than negative responders. Except for visceral fat, the entire cohort showed significant decreases in all measures of body composition (P < 0.005) after weight loss, with greater decreases in body weight, body mass index, and FM index in positive responders (P < 0.005). Finally, data revealed that only positive responders showed decreases in LBM, LBM index, and hsCRP levels after weight loss (P between 0.01 and 0.001). An important interindividual variability in changes in glucose disposal after weight loss is observed. Interestingly, participants who display improvements in glucose disposal also show significant decreases in LBM, LBM index, and hsCRP after weight loss.

48 CFR 45.605 - Inventory disposal reports.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Inventory disposal reports... MANAGEMENT GOVERNMENT PROPERTY Reporting, Reutilization, and Disposal 45.605 Inventory disposal reports. The plant clearance officer shall promptly prepare an SF 1424, Inventory Disposal Report, following...

10 CFR 61.52 - Land disposal facility operation and disposal site closure.

Code of Federal Regulations, 2013 CFR

2013-01-01

... meters below the top surface of the cover or must be disposed of with intruder barriers that are designed... mapped by means of a land survey. Near-surface disposal units must be marked in such a way that the boundaries of each unit can be easily defined. Three permanent survey marker control points, referenced to...

10 CFR 61.52 - Land disposal facility operation and disposal site closure.

Code of Federal Regulations, 2014 CFR

2014-01-01

... meters below the top surface of the cover or must be disposed of with intruder barriers that are designed... mapped by means of a land survey. Near-surface disposal units must be marked in such a way that the boundaries of each unit can be easily defined. Three permanent survey marker control points, referenced to...

10 CFR 61.52 - Land disposal facility operation and disposal site closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... meters below the top surface of the cover or must be disposed of with intruder barriers that are designed... mapped by means of a land survey. Near-surface disposal units must be marked in such a way that the boundaries of each unit can be easily defined. Three permanent survey marker control points, referenced to...

10 CFR 61.52 - Land disposal facility operation and disposal site closure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... meters below the top surface of the cover or must be disposed of with intruder barriers that are designed... mapped by means of a land survey. Near-surface disposal units must be marked in such a way that the boundaries of each unit can be easily defined. Three permanent survey marker control points, referenced to...

10 CFR 61.52 - Land disposal facility operation and disposal site closure.

Code of Federal Regulations, 2012 CFR

2012-01-01

... meters below the top surface of the cover or must be disposed of with intruder barriers that are designed... mapped by means of a land survey. Near-surface disposal units must be marked in such a way that the boundaries of each unit can be easily defined. Three permanent survey marker control points, referenced to...

Reuse of disposable laparoscopic instruments: cost analysis*

PubMed Central

DesCôteaux, Jean-Gaston; Tye, Lucille; Poulin, Eric C.

1996-01-01

Objective To evaluate the cost benefits of reusing disposable laparoscopic instruments. Design A cost-analysis study based on a review of laparoscopic and thoracoscopic procedures performed between August 1990 and January 1994, including analysis of disposable instrument use, purchase records, and reprocessing costs for each instrument. Setting The general surgery department of a 461-bed teaching hospital where disposable laparoscopic instruments are routinely reused according to internally validated reprocessing protocols. Methods Laparoscopic and thoracoscopic interventions performed between August 1990 and January 1994 for which the number and types of disposable laparoscopic instruments were standardized. Main Outcome Measures Reprocessing cost per instrument, the savings realized by reusing disposable laparoscopic instruments and the cost-efficient number of reuses per instrument. Results The cost of reprocessing instruments varied from $2.64 (Can) to $4.66 for each disposable laparoscopic instrument. Purchases of 10 commonly reused disposable laparoscopic instruments totalled $183 279, and the total reprocessing cost was estimated at $35 665 for the study period. Not reusing disposable instruments would have cost $527 575 in instrument purchases for the same period. Disposable laparoscopic instruments were reused 1.7 to 68 times each. Conclusions Under carefully monitored conditions and strict guidelines, reuse of disposable laparoscopic and thoracoscopic instruments can be cost-effective. PMID:8769924

48 CFR 2845.603 - Disposal methods.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Disposal methods. 2845.603 Section 2845.603 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 2845.603 Disposal methods...

48 CFR 2845.603 - Disposal methods.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Disposal methods. 2845.603 Section 2845.603 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE Contract Management GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 2845.603 Disposal methods...

48 CFR 945.603 - Disposal methods.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Disposal methods. 945.603 Section 945.603 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 945.603 Disposal methods. ...

48 CFR 945.603 - Disposal methods.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Disposal methods. 945.603 Section 945.603 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 945.603 Disposal methods. ...

48 CFR 2845.603 - Disposal methods.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Disposal methods. 2845.603 Section 2845.603 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 2845.603 Disposal methods...

48 CFR 2845.603 - Disposal methods.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Disposal methods. 2845.603 Section 2845.603 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 2845.603 Disposal methods...

48 CFR 945.603 - Disposal methods.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Disposal methods. 945.603 Section 945.603 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 945.603 Disposal methods. ...

48 CFR 2845.603 - Disposal methods.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Disposal methods. 2845.603 Section 2845.603 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 2845.603 Disposal methods...

Aquatic disposal field investigations Galveston, Texas, offshore disposal site. Evaluative summary. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wright, T.D.; Mathis, D.B.; Brannon, J.M.

This study was part of an investigation to determine the environmental effects of offshore dredged material disposal at Galveston, Texas. The biological portion of the study was conducted in two phases: a pilot survey of the dredged material disposal site (DMDS) to determine the areal distribution of the biota and sediments; and an experimental study to assess the effect of dredged material disposal on the biota at selected sites in the DMDS. Three experimental sites were investigated: a sandy bottom that received sand, shell, and silt-clay dredged material; a muddy bottom that received sand and shell dredged material; and amore » muddy bottom that received silt-clay dredged material. The magnitude of the effect on the benthic populations could not be accurately assessed because adequate predisposal data on natural sediment and benthic population changes were not available. Dredged material deposits had no apparent effect on feeding habits of fish or on the distribution of nekton, although some nektonic species may have congregated in the turbid water following dredged material disposal. Zooplankton and phytoplankton studies detected no population changes during disposal that could not have been due to sampling error. It is probable that sudden abiotic changes and commercial fishing activities cause more destruction of biota than dredging-related activities.« less

Restrictive vs. non-restrictive composition: a magnetoencephalography study

PubMed Central

Leffel, Timothy; Lauter, Miriam; Westerlund, Masha; Pylkkänen, Liina

2014-01-01

Recent research on the brain mechanisms underlying language processing has implicated the left anterior temporal lobe (LATL) as a central region for the composition of simple phrases. Because these studies typically present their critical stimuli without contextual information, the sensitivity of LATL responses to contextual factors is unknown. In this magnetoencephalography (MEG) study, we employed a simple question-answer paradigm to manipulate whether a prenominal adjective or determiner is interpreted restrictively, i.e., as limiting the set of entities under discussion. Our results show that the LATL is sensitive to restriction, with restrictive composition eliciting higher responses than non-restrictive composition. However, this effect was only observed when the restricting element was a determiner, adjectival stimuli showing the opposite pattern, which we hypothesise to be driven by the special pragmatic properties of non-restrictive adjectives. Overall, our results demonstrate a robust sensitivity of the LATL to high level contextual and potentially also pragmatic factors. PMID:25379512

Application for a Permit to Operate a Class III Solid Waste Disposal Site at the Nevada Test Site Area 5 Asbestiform Low-Level Solid Waste Disposal Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

NSTec Environmental Programs

The NTS solid waste disposal sites must be permitted by the state of Nevada Solid Waste Management Authority (SWMA). The SWMA for the NTS is the Nevada Division of Environmental Protection, Bureau of Federal Facilities (NDEP/BFF). The U.S. Department of Energy's National Nuclear Security Administration Nevada Site Office (NNSA/NSO) as land manager (owner), and National Security Technologies (NSTec), as operator, will store, collect, process, and dispose all solid waste by means that do not create a health hazard, a public nuisance, or cause impairment of the environment. NTS disposal sites will not be included in the Nye County Solid Wastemore » Management Plan. The NTS is located approximately 105 kilometers (km) (65 miles [mi]) northwest of Las Vegas, Nevada (Figure 1). The U.S. Department of Energy (DOE) is the federal lands management authority for the NTS, and NSTec is the Management and Operations contractor. Access on and off the NTS is tightly controlled, restricted, and guarded on a 24-hour basis. The NTS has signs posted along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NTS. The Area 5 RWMS is the location of the permitted facility for the Solid Waste Disposal Site (SWDS). The Area 5 RWMS is located near the eastern edge of the NTS (Figure 2), approximately 26 km (16 mi) north of Mercury, Nevada. The Area 5 RWMS is used for the disposal of low-level waste (LLW) and mixed low-level waste. Many areas surrounding the RWMS have been used in conducting nuclear tests. A Notice of Intent to operate the disposal site as a Class III site was submitted to the state of Nevada on January 28, 1994, and was acknowledged as being received in a letter to the NNSA/NSO on August 30, 1994. Interim approval to operate a Class III SWDS for regulated asbestiform low-level waste (ALLW) was authorized on August 12, 1996 (in letter from Paul Liebendorfer to Runore Wycoff), with operations to be conducted in accordance with the

36 CFR 228.57 - Types of disposal.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Types of disposal. 228.57 Section 228.57 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE MINERALS Disposal of Mineral Materials Types and Methods of Disposal § 228.57 Types of disposal. Except as provided...

36 CFR 228.57 - Types of disposal.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Types of disposal. 228.57 Section 228.57 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE MINERALS Disposal of Mineral Materials Types and Methods of Disposal § 228.57 Types of disposal. Except as provided...

36 CFR 228.57 - Types of disposal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Types of disposal. 228.57 Section 228.57 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE MINERALS Disposal of Mineral Materials Types and Methods of Disposal § 228.57 Types of disposal. Except as provided...

36 CFR 228.57 - Types of disposal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Types of disposal. 228.57 Section 228.57 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE MINERALS Disposal of Mineral Materials Types and Methods of Disposal § 228.57 Types of disposal. Except as provided...

Safe Disposal of Highly Reactive Chemicals.

ERIC Educational Resources Information Center

Lunn, George; Sansone, Eric B.

1994-01-01

Provides specific procedures for the disposal of a variety of highly reactive chemicals and reports the results of a study of their safe disposal. Disposal of some problematic sulfur-containing compounds are included. Procedures are based on a combination of literature review and author development. (LZ)

40 CFR 761.97 - Export for disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Export for disposal. 761.97 Section... PROHIBITIONS Transboundary Shipments of PCBs for Disposal § 761.97 Export for disposal. (a) General provisions. No person may export PCBs or PCB Items for disposal without an exemption, except that: (1) PCBs and...

36 CFR 13.1008 - Solid waste disposal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Solid waste disposal. 13.1008... § 13.1008 Solid waste disposal. (a) A solid waste disposal site may accept non-National Park Service solid waste generated within the boundaries of the park area. (b) A solid waste disposal site may be...

36 CFR 13.1604 - Solid waste disposal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Solid waste disposal. 13.1604... Solid waste disposal. (a) A solid waste disposal site may accept non-National Park Service solid waste generated within the boundaries of the park area. (b) A solid waste disposal site may be located within one...

36 CFR 13.1118 - Solid waste disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Solid waste disposal. 13.1118... Provisions § 13.1118 Solid waste disposal. (a) A solid waste disposal site may accept non-National Park Service solid waste generated within the boundaries of the park area. (b) A solid waste disposal site may...

36 CFR 13.1604 - Solid waste disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Solid waste disposal. 13.1604... Solid waste disposal. (a) A solid waste disposal site may accept non-National Park Service solid waste generated within the boundaries of the park area. (b) A solid waste disposal site may be located within one...

36 CFR 13.1912 - Solid waste disposal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Solid waste disposal. 13.1912....1912 Solid waste disposal. (a) A solid waste disposal site may accept non-National Park Service solid waste generated within the boundaries of the park area. (b) A solid waste disposal site may be located...

36 CFR 13.1008 - Solid waste disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Solid waste disposal. 13.1008... § 13.1008 Solid waste disposal. (a) A solid waste disposal site may accept non-National Park Service solid waste generated within the boundaries of the park area. (b) A solid waste disposal site may be...

36 CFR 13.1118 - Solid waste disposal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Solid waste disposal. 13.1118... Provisions § 13.1118 Solid waste disposal. (a) A solid waste disposal site may accept non-National Park Service solid waste generated within the boundaries of the park area. (b) A solid waste disposal site may...

40 CFR 761.65 - Storage for disposal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Storage for disposal. 761.65 Section... PROHIBITIONS Storage and Disposal § 761.65 Storage for disposal. This section applies to the storage for... greater. (a)(1) Storage limitations. Any PCB waste shall be disposed of as required by subpart D of this...

40 CFR 761.65 - Storage for disposal.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Storage for disposal. 761.65 Section... PROHIBITIONS Storage and Disposal § 761.65 Storage for disposal. This section applies to the storage for... greater. (a)(1) Storage limitations. Any PCB waste shall be disposed of as required by subpart D of this...

10 CFR 850.32 - Waste disposal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Waste disposal. 850.32 Section 850.32 Energy DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM Specific Program Requirements § 850.32 Waste disposal...-contaminated equipment and other items that are disposed of as waste, through the application of waste...

Medications at school: disposing of pharmaceutical waste.

PubMed

Taras, Howard; Haste, Nina M; Berry, Angela T; Tran, Jennifer; Singh, Renu F

2014-03-01

This project quantified and categorized medications left unclaimed by students at the end of the school year. It determined the feasibility of a model medication disposal program and assessed school nurses' perceptions of environmentally responsible medication disposal. At a large urban school district all unclaimed medications were collected at the end of a school year to determine the extent and nature of this problem. Nurses documented unclaimed medications and transported them to a central district location. An environmentally responsible medication disposal program, consisting of sealed containers bound for a local hospital's disposal system, was implemented. In a school district of approximately 133,000 students, there were 926 different medications abandoned at the end of a school year brought to a central disposal area. Nurses complied with the newly implemented protocol. Information collected from nurses indicates acceptance of the program. Disposal of unclaimed medications at a central location, use of secured containers, and transportation to a hospital for environmentally responsible disposal proved to be feasible and acceptable to the staff. Unclaimed medications at school each year pose a potentially huge environmental risk when disposed of improperly. It is feasible to implement an environmentally responsible medication disposal protocol at schools. © 2014, American School Health Association.

Ultimate disposal of scrubber wastes

NASA Technical Reports Server (NTRS)

Cohenour, B. C.

1978-01-01

Part of the initial concern with using the wet scrubbers on the hypergolic propellants was the subsequential disposal of the liquid wastes. To do this, consideration was given to all possible methods to reduce the volume of the wastes and stay within the guidelines established by the state and federal environmental protection agencies. One method that was proposed was the use of water hyacinths in disposal ponds to reduce the waste concentration in the effluent to less than EPA tolerable levels. This method was under consideration and even in use by private industry, municipal governments, and NASA for upgrading existing wastewater treatment facilities to a tertiary system. The use of water hyacinths in disposal ponds appears to be a very cost-effective method for reduction and disposal of hypergolic propellants.

ICRP PUBLICATION 122: radiological protection in geological disposal of long-lived solid radioactive waste.

PubMed

Weiss, W; Larsson, C-M; McKenney, C; Minon, J-P; Mobbs, S; Schneider, T; Umeki, H; Hilden, W; Pescatore, C; Vesterlind, M

2013-06-01

This report updates and consolidates previous recommendations of the International Commission on Radiological Protection (ICRP) related to solid waste disposal (ICRP, 1985, 1997b, 1998). The recommendations given apply specifically to geological disposal of long-lived solid radioactive waste. The report explains how the ICRP system of radiological protection described in Publication 103 (ICRP, 2007) can be applied in the context of the geological disposal of long-lived solid radioactive waste. Although the report is written as a standalone document, previous ICRP recommendations not dealt with in depth in the report are still valid. The 2007 ICRP system of radiological protection evolves from the previous process-based protection approach relying on the distinction between practices and interventions by moving to an approach based on the distinction between three types of exposure situation: planned, emergency and existing. The Recommendations maintains the Commission's three fundamental principles of radiological protection namely: justification, optimisation of protection and the application of dose limits. They also maintain the current individual dose limits for effective dose and equivalent dose from all regulated sources in planned exposure situations. They re-enforce the principle of optimisation of radiological protection, which applies in a similar way to all exposure situations, subject to restrictions on individual doses: constraints for planned exposure situations, and reference levels for emergency and existing exposure situations. The Recommendations also include an approach for developing a framework to demonstrate radiological protection of the environment. This report describes the different stages in the life time of a geological disposal facility, and addresses the application of relevant radiological protection principles for each stage depending on the various exposure situations that can be encountered. In particular, the crucial factor that

Disposal of Some Problem Chemicals.

ERIC Educational Resources Information Center

Journal of Chemical Education, 1978

1978-01-01

Describes procedures for the disposal of chemicals commonly used in secondary school chemistry laboratories. Special reference is given to inorganic salts. It is suggested that cyanides and other highly toxic salts should be disposed of by experts. (MA)

Nuclear waste disposal in space

NASA Technical Reports Server (NTRS)

Burns, R. E.; Causey, W. E.; Galloway, W. E.; Nelson, R. W.

1978-01-01

Work on nuclear waste disposal in space conducted by the George C. Marshall Space Flight Center, National Aeronautics and Space Administration, and contractors are reported. From the aggregate studies, it is concluded that space disposal of nuclear waste is technically feasible.

Evaluation of the validity and reliability of A-scan ultrasound biometry with a single use disposable cover.

PubMed

Cass, K; Thompson, C M; Tromans, C; Wood, I C J

2002-03-01

The UK Medical Devices Agency has suggested that ophthalmic practitioners should, where practicable and not compromising clinical outcome, restrict corneal contact devices to single patient use to minimise a remote theoretical risk of transmission of new variant Creutzfeldt-Jakob disease (vCJD). This study reports on a modified technique of ultrasound A-scan biometry that complies with the MDA recommendations. The right eyes of 37 consecutive hospital patients had a series of biometry readings taken with a Humphrey 820 A-scan instrument with a plane wave transducer use d conventionally and with the addition of a disposable latex cover. Intrasessional repeatability of axial length measurements was similar for conventional readings--mean difference 0.027 mm, 95% confidence intervals (CI) +/- 0.44 mm and those taken with a disposable cover (0.028 mm, CI +/- 0.38). Intersessional repeatability was equivalent with (0.002 mm, CI +.- 0.51) and without a cover (0.03 mm, CI +/- 0.51). Readings with a cover were not significantly different from those without (paired t test; p >0.05), but tended to be greater (mean difference 0.085 mm, CI +/- 0.60). These findings suggest that corneal contact biometry with a disposable cover is a viable and theoretically safer alternative to the conventional technique.

Chemical Waste Management and Disposal.

ERIC Educational Resources Information Center

Armour, Margaret-Ann

1988-01-01

Describes simple, efficient techniques for treating hazardous chemicals so that nontoxic and nonhazardous residues are formed. Discusses general rules for management of waste chemicals from school laboratories and general techniques for the disposal of waste or surplus chemicals. Lists specific disposal reactions. (CW)

10 CFR 20.2005 - Disposal of specific wastes.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Disposal of specific wastes. 20.2005 Section 20.2005 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2005 Disposal of specific wastes. (a) A licensee may dispose of the following licensed material as if it were...

10 CFR 20.2005 - Disposal of specific wastes.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Disposal of specific wastes. 20.2005 Section 20.2005 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2005 Disposal of specific wastes. (a) A licensee may dispose of the following licensed material as if it were...

48 CFR 45.604-1 - Disposal methods.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Disposal methods. 45.604-1 Section 45.604-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Reutilization, and Disposal 45.604-1 Disposal methods. (a) Except as provided...

48 CFR 45.604-1 - Disposal methods.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Disposal methods. 45.604-1 Section 45.604-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Reutilization, and Disposal 45.604-1 Disposal methods. (a) Except as provided...

21 CFR 880.6820 - Medical disposable scissors.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Medical disposable scissors. 880.6820 Section 880...) MEDICAL DEVICES GENERAL HOSPITAL AND PERSONAL USE DEVICES General Hospital and Personal Use Miscellaneous Devices § 880.6820 Medical disposable scissors. (a) Identification. Medical disposable scissors are...

21 CFR 880.6820 - Medical disposable scissors.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical disposable scissors. 880.6820 Section 880...) MEDICAL DEVICES GENERAL HOSPITAL AND PERSONAL USE DEVICES General Hospital and Personal Use Miscellaneous Devices § 880.6820 Medical disposable scissors. (a) Identification. Medical disposable scissors are...

21 CFR 880.6060 - Medical disposable bedding.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical disposable bedding. 880.6060 Section 880...) MEDICAL DEVICES GENERAL HOSPITAL AND PERSONAL USE DEVICES General Hospital and Personal Use Miscellaneous Devices § 880.6060 Medical disposable bedding. (a) Identification. Medical disposable bedding is a device...

21 CFR 880.6060 - Medical disposable bedding.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Medical disposable bedding. 880.6060 Section 880...) MEDICAL DEVICES GENERAL HOSPITAL AND PERSONAL USE DEVICES General Hospital and Personal Use Miscellaneous Devices § 880.6060 Medical disposable bedding. (a) Identification. Medical disposable bedding is a device...

43 CFR 2743.2 - New disposal sites.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Public Purposes Act: Solid Waste Disposal § 2743.2 New disposal sites. (a) Public lands may be conveyed... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false New disposal sites. 2743.2 Section 2743.2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT...

43 CFR 2743.2 - New disposal sites.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Public Purposes Act: Solid Waste Disposal § 2743.2 New disposal sites. (a) Public lands may be conveyed... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false New disposal sites. 2743.2 Section 2743.2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT...

43 CFR 2743.2 - New disposal sites.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Public Purposes Act: Solid Waste Disposal § 2743.2 New disposal sites. (a) Public lands may be conveyed... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false New disposal sites. 2743.2 Section 2743.2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT...

41 CFR 50-204.29 - Waste disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Waste disposal. 50-204.29 Section 50-204.29 Public Contracts and Property Management Other Provisions Relating to Public Contracts... Radiation Standards § 50-204.29 Waste disposal. No employer shall dispose of radioactive material except by...

FFTF disposable solid waste cask

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomson, J. D.; Goetsch, S. D.

1983-01-01

Disposal of radioactive waste from the Fast Flux Test Facility (FFTF) will utilize a Disposable Solid Waste Cask (DSWC) for the transport and burial of irradiated stainless steel and inconel materials. Retrievability coupled with the desire for minimal facilities and labor costs at the disposal site identified the need for the DSWC. Design requirements for this system were patterned after Type B packages as outlined in 10 CFR 71 with a few exceptions based on site and payload requirements. A summary of the design basis, supporting analytical methods and fabrication practices developed to deploy the DSWC is provided in thismore » paper.« less

50 CFR 12.33 - Disposal.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 1 2011-10-01 2011-10-01 false Disposal. 12.33 Section 12.33 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION...) Donation or loan; (4) Sale; or (5) Destruction. In the exercise of the disposal authority, the Director...

50 CFR 12.33 - Disposal.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Disposal. 12.33 Section 12.33 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION...) Donation or loan; (4) Sale; or (5) Destruction. In the exercise of the disposal authority, the Director...

40 CFR 279.81 - Disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Disposal. 279.81 Section 279.81 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF USED OIL Standards for Use as a Dust Suppressant and Disposal of Used Oil § 279.81...

40 CFR 279.81 - Disposal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 27 2014-07-01 2014-07-01 false Disposal. 279.81 Section 279.81 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF USED OIL Standards for Use as a Dust Suppressant and Disposal of Used Oil § 279.81...

40 CFR 279.81 - Disposal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 27 2011-07-01 2011-07-01 false Disposal. 279.81 Section 279.81 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF USED OIL Standards for Use as a Dust Suppressant and Disposal of Used Oil § 279.81...

40 CFR 279.81 - Disposal.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 28 2013-07-01 2013-07-01 false Disposal. 279.81 Section 279.81 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF USED OIL Standards for Use as a Dust Suppressant and Disposal of Used Oil § 279.81...

Project Management Plan for the Idaho National Engineering Laboratory Waste Isolation Pilot Plant Experimental Test Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Connolly, M.J.; Sayer, D.L.

1993-11-01

EG&G Idaho, Inc. and Argonne National Laboratory-West (ANL-W) are participating in the Idaho National Engineering Laboratory`s (INEL`s) Waste Isolation Pilot Plant (WIPP) Experimental Test Program (WETP). The purpose of the INEL WET is to provide chemical, physical, and radiochemical data on transuranic (TRU) waste to be stored at WIPP. The waste characterization data collected will be used to support the WIPP Performance Assessment (PA), development of the disposal No-Migration Variance Petition (NMVP), and to support the WIPP disposal decision. The PA is an analysis required by the Code of Federal Regulations (CFR), Title 40, Part 191 (40 CFR 191), whichmore » identifies the processes and events that may affect the disposal system (WIPP) and examines the effects of those processes and events on the performance of WIPP. A NMVP is required for the WIPP by 40 CFR 268 in order to dispose of land disposal restriction (LDR) mixed TRU waste in WIPP. It is anticipated that the detailed Resource Conservation and Recovery Act (RCRA) waste characterization data of all INEL retrievably-stored TRU waste to be stored in WIPP will be required for the NMVP. Waste characterization requirements for PA and RCRA may not necessarily be identical. Waste characterization requirements for the PA will be defined by Sandia National Laboratories. The requirements for RCRA are defined in 40 CFR 268, WIPP RCRA Part B Application Waste Analysis Plan (WAP), and WIPP Waste Characterization Program Plan (WWCP). This Project Management Plan (PMP) addresses only the characterization of the contact handled (CH) TRU waste at the INEL. This document will address all work in which EG&G Idaho is responsible concerning the INEL WETP. Even though EG&G Idaho has no responsibility for the work that ANL-W is performing, EG&G Idaho will keep a current status and provide a project coordination effort with ANL-W to ensure that the INEL, as a whole, is effectively and efficiently completing the requirements

43 CFR 3596.2 - Disposal of waste.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Disposal of waste. 3596.2 Section 3596.2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT... OPERATIONS Waste From Mining or Milling § 3596.2 Disposal of waste. The operator/lessee shall dispose of all...

43 CFR 3596.2 - Disposal of waste.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Disposal of waste. 3596.2 Section 3596.2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT... OPERATIONS Waste From Mining or Milling § 3596.2 Disposal of waste. The operator/lessee shall dispose of all...

Relative risk assessment of cruise ships biosolids disposal alternatives.

PubMed

Avellaneda, Pedro M; Englehardt, James D; Olascoaga, Josefina; Babcock, Elizabeth A; Brand, Larry; Lirman, Diego; Rogge, Wolfgang F; Solo-Gabriele, Helena; Tchobanoglous, George

2011-10-01

A relative risk assessment of biosolids disposal alternatives for cruise ships is presented in this paper. The area of study encompasses islands and marine waters of the Caribbean Sea. The objective was to evaluate relative human health and ecological risks of (a) dewatering/incineration, (b) landing the solids for disposal, considering that in some countries land-disposed solids might be discharged in the near-shore environment untreated, and (c) deep ocean disposal. Input to the Bayesian assessment consisted of professional judgment based on available literature and modeling information, data on constituent concentrations in cruise ship biosolids, and simulations of constituent concentrations in Caribbean waters assuming ocean disposal. Results indicate that human health and ecological risks associated with land disposal and shallow ocean disposal are higher than those of the deep ocean disposal and incineration. For incineration, predicted ecological impacts were lower relative to deep ocean disposal before considering potential impacts of carbon emissions. Copyright © 2011 Elsevier Ltd. All rights reserved.

Landfill disposal systems.

PubMed

Slimak, K M

1978-12-01

The current status of landfill disposal of hazardous wastes in the United States is indicated by presenting descriptions of six operating landfills. These landfills illustrate the variety of techniques that exist in landfill disposal of hazardous wastes. Although some landfills more effectively isolate hazardous waste than others, all landfills must deal with the following problems. Leachate from hazardous waste landfills is generally highly polluted. Most landfills attempt to contain leachate at the site and prevent its discharge to surface or groundwaters. To retain leachate within a disposal area, subsurface barriers of materials such as concrete, asphalt, butyl rubber, vinyl, and clay are used. It is difficult to assure that these materials can seal a landfill indefinitely. When a subsurface barrier fails, the leachate enters the groundwater in a concentrated, narrow band which may bypass monitoring wells. Once a subsurface barrier has failed, repairs are time-consuming and costly, since the waste above the repair site may have to be removed. The central problem in landfill disposal is leachate control. Recent emphasis has been on developing subsurface barriers to contain the wastes and any leachate. Future emphasis should also be on techniques for removing water from hazardous wastes before they are placed in landfills, and on methods for preventing contact of the wastes with water during and after disposal operations. When leachate is eliminated, the problems of monitoring, and subsurface barrier failure and repair can be addressed, and a waste can be effectively isolated.A surface seal landfill design is recommended for maintaining the dry state of solid hazardous wastes and for controlling leachate. Any impervious liner is utilized over the top of the landfill to prevent surface water from seeping into the waste. The surface barrier is also the site where monitoring and maintenance activities are focused. Barrier failure can be detected by visual

Magnetically focused liquid drop radiator

DOEpatents

Botts, Thomas E.; Powell, James R.; Lenard, Roger

1986-01-01

A magnetically focused liquid drop radiator for application in rejecting rgy from a spacecraft, characterized by a magnetizable liquid or slurry disposed in operative relationship within the liquid droplet generator and its fluid delivery system, in combination with magnetic means disposed in operative relationship around a liquid droplet collector of the LDR. The magnetic means are effective to focus streams of droplets directed from the generator toward the collector, thereby to assure that essentially all of the droplets are directed into the collector, even though some of the streams may be misdirected as they leave the generator. The magnetic focusing means is also effective to suppress splashing of liquid when the droplets impinge on the collector.

Magnetically focused liquid drop radiator

DOEpatents

Botts, T.E.; Powell, J.R.; Lenard, R.

1984-12-10

A magnetically focused liquid drop radiator for application in rejecting energy from a spacecraft, characterized by a magnetizable liquid or slurry disposed in operative relationship within the liquid droplet generator and its fluid delivery system, in combination with magnetic means disposed in operative relationship around a liquid droplet collector of the LDR. The magnetic means are effective to focus streams of droplets directed from the generator toward the collector, thereby to assure that essentially all of the droplets are directed into the collector, even though some of the streams may be misdirected as they leave the generator. The magnetic focusing means is also effective to suppress splashing of liquid when the droplets impinge on the collector.

SU-E-J-215: Towards MR-Only Image Guided Identification of Calcifications and Brachytherapy Seeds: Application to Prostate and Breast LDR Implant Dosimetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elzibak, A; Fatemi-Ardekani, A; Soliman, A

Purpose: To identify and analyze the appearance of calcifications and brachytherapy seeds on magnitude and phase MRI images and to investigate whether they can be distinguished from each other on corrected phase images for application to prostate and breast low dose rate (LDR) implant dosimetry. Methods: An agar-based gel phantom containing two LDR brachytherapy seeds (Advantage Pd-103, IsoAid, 0.8mm diameter, 4.5mm length) and two spherical calcifications (large: 7mm diameter and small: 4mm diameter) was constructed and imaged on a 3T Philips MR scanner using a 16-channel head coil and a susceptibility weighted imaging (SWI) sequence (2mm slices, 320mm FOV, TR/more » TE= 26.5/5.3ms, 15 degree flip angle). The phase images were unwrapped and corrected using a 32×32, 2D Hanning high pass filter to remove background phase noise. Appearance of the seeds and calcifications was assessed visually and quantitatively using Osirix (http://www.osirix-viewer.com/). Results: As expected, calcifications and brachytherapy seeds appeared dark (hypointense) relative to the surrounding gel on the magnitude MRI images. The diameter of each seed without the surrounding artifact was measured to be 0.1 cm on the magnitude image, while diameters of 0.79 and 0.37 cm were measured for the larger and smaller calcifications, respectively. On the corrected phase images, the brachytherapy seeds and the calcifications appeared bright (hyperintense). The diameter of the seeds was larger on the phase images (0.17 cm) likely due to the dipole effect. Conclusion: MRI has the best soft tissue contrast for accurate organ delineation leading to most accurate implant dosimetry. This work demonstrated that phase images can potentially be useful in identifying brachytherapy seeds and calcifications in the prostate and breast due to their bright appearance, which helps in their visualization and quantification for accurate dosimetry using MR-only. Future work includes optimizing phase filters to best

Concept for Underground Disposal of Nuclear Waste

NASA Technical Reports Server (NTRS)

Bowyer, J. M.

1987-01-01

Packaged waste placed in empty oil-shale mines. Concept for disposal of nuclear waste economically synergistic with earlier proposal concerning backfilling of oil-shale mines. New disposal concept superior to earlier schemes for disposal in hard-rock and salt mines because less uncertainty about ability of oil-shale mine to contain waste safely for millenium.

36 CFR 222.30 - Disposal of carcasses.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Disposal of carcasses. 222.30... MANAGEMENT Management of Wild Free-Roaming Horses and Burros § 222.30 Disposal of carcasses. Carcasses of animals that have lost their status as wild free-roaming horses or burros may be disposed of in any...

Topological methods for the comparison of structures using LDR-brachytherapy of the prostate as an example.

PubMed

Schiefer, H; von Toggenburg, F; Seelentag, W W; Plasswilm, L; Ries, G; Schmid, H-P; Leippold, T; Krusche, B; Roth, J; Engeler, D

2009-08-21

The dose coverage of low dose rate (LDR)-brachytherapy for localized prostate cancer is monitored 4-6 weeks after intervention by contouring the prostate on computed tomography and/or magnetic resonance imaging sets. Dose parameters for the prostate (V100, D90 and D80) provide information on the treatment quality. Those depend strongly on the delineation of the prostate contours. We therefore systematically investigated the contouring process for 21 patients with five examiners. The prostate structures were compared with one another using topological procedures based on Boolean algebra. The coincidence number C(V) measures the agreement between a set of structures. The mutual coincidence C(i, j) measures the agreement between two structures i and j, and the mean coincidence C(i) compares a selected structure i with the remaining structures in a set. All coincidence parameters have a value of 1 for complete coincidence of contouring and 0 for complete absence. The five patients with the lowest C(V) values were discussed, and rules for contouring the prostate have been formulated. The contouring and assessment were repeated after 3 months for the same five patients. All coincidence parameters have been improved after instruction. This shows objectively that training resulted in more consistent contouring across examiners.

Radioactive waste disposal fees-Methodology for calculation

NASA Astrophysics Data System (ADS)

Bemš, Július; Králík, Tomáš; Kubančák, Ján; Vašíček, Jiří; Starý, Oldřich

2014-11-01

This paper summarizes the methodological approach used for calculation of fee for low- and intermediate-level radioactive waste disposal and for spent fuel disposal. The methodology itself is based on simulation of cash flows related to the operation of system for waste disposal. The paper includes demonstration of methodology application on the conditions of the Czech Republic.

48 CFR 245.603 - Disposal methods.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Disposal methods. 245.603 Section 245.603 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Contractor Inventory 245.603 Disposal methods. ...

A model for calculating effects of liquid waste disposal in deep saline aquifer

USGS Publications Warehouse

Intercomp Resource Development and Engineering, Inc.

1976-01-01

Injection of liquid industrial wastes into confined underground saline aquifers can offer a good disposal alternative from both environmental and economic considerations. One of the needs in choosing from among several disposal alternatives is a means of evaluating the influence such an injection will have on the aquifer system. This report describes a mathematical model to accomplish this purpose.The objective of the contract was to develop a three-dimensional transient mathematical model which would accurately simulate behavior of waste injection into deep saline aquifers. Fluid properties, density and viscosity are functions of pressure, temperature and composition to provide a comprehensive assessment tool. The model is a finite-difference numerical solution of the partial differential equations describingsingle phase flow in the aquifer,energy transport by convection and conduction, andcompositional changes in the aquifer fluid.The model is not restricted to examining waste disposal operations. It can be used effectively to evaluate fresh water storage in saline aquifers, hot water storage in underground aquifers, salt water intrusion into groundwater flow systems and other similar applications.The primary advantages of the present model can be summarized as:The model is user-oriented for easy application to full-scale evaluation needs.The model is fully three-dimensional and transient.The model is comprehensive accounting for density and viscosity variations in the aquifer due to temperature or compositional changes.The model includes the effects of hydrodynamic dispersion in both the temperature and compositional mixing between resident and injected fluids.The model energy balance includes the effects of pressure. This can be important in deep aquifer systems where the viscous pressure gradient is significant.The model uses second-order correct space and time approximations to the convective terms. This minimizes the numerical dispersion problem.The model is

Disposal site quality team final report

DOT National Transportation Integrated Search

2001-09-01

The disposal site quality team was formed in July 2000 to address Caltrans (Department) and Federal Highway Administration (FHWA) policies on disposal, staging, and borrow areas (DSB), including plant sites, contractor yards, and access roads. Caltra...

Nuclear waste disposal in subseabed geologic formatons: the Seabed Disposal Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, D.R.

1979-05-01

The goal of the Seabed Disposal Program is to assess the technical and environmental feasibility of using geologic formations under the sea floor for the disposal of processed high-level radioactive wastes or repackaged spent reactor fuel. Studies are focused on the abyssal hill regions of the sea floors in the middle of tectonic plates and under massive surface current gyres. The red-clay sediments here are from 50 to 100 meters thick, are continuously depositional (without periods of erosion), and have been geologically and climatologically stable for millions of years. Mineral deposits and biological activity are minimal, and bottom currents aremore » weak and variable. Five years of research have revealed no technological reason why nuclear waste disposal in these areas would be impractical. However, scientific assessment is not complete. Also, legal political, and sociological factors may well become the governing elements in such use of international waters. These factors are being examined as part of the work of the Seabed Working Group, an international adjunct of the Seabed Program, with members from France, England, Japan, Canada, and the United States.« less

Evaluation of the validity and reliability of A-scan ultrasound biometry with a single use disposable cover

PubMed Central

Cass, K; Thompson, C M; Tromans, C; Wood, I C J

2002-01-01

Background: The UK Medical Devices Agency has suggested that ophthalmic practitioners should, where practicable and not compromising clinical outcome, restrict corneal contact devices to single patient use to minimise a remote theoretical risk of transmission of new variant Creutzfeldt-Jakob disease (vCJD). This study reports on a modified technique of ultrasound A-scan biometry that complies with the MDA recommendations. Methods: The right eyes of 37 consecutive hospital patients had a series of biometry readings taken with a Humphrey 820 A-scan instrument with a plane wave transducer use d conventionally and with the addition of a disposable latex cover. Results: Intrasessional repeatability of axial length measurements was similar for conventional readings—mean difference 0.027 mm, 95% confidence intervals (CI) ± 0.44 mm and those taken with a disposable cover (0.028 mm, CI ± 0.38). Intersessional repeatability was equivalent with (0.002 mm, CI ± 0.51) and without a cover (0.03 mm, CI ± 0.51). Readings with a cover were not significantly different from those without (paired t test; p >0.05), but tended to be greater (mean difference 0.085 mm, CI ± 0.60). Conclusions: These findings suggest that corneal contact biometry with a disposable cover is a viable and theoretically safer alternative to the conventional technique. PMID:11864896

Are Disposable and Standard Gonioscopy Lenses Comparable?

PubMed

Lee, Bonny; Szirth, Bernard C; Fechtner, Robert D; Khouri, Albert S

2017-04-01

Gonioscopy is important in the evaluation and treatment of glaucoma. With increased scrutiny of acceptable sterilization processes for health care instruments, disposable gonioscopy lenses have recently been introduced. Single-time use lenses are theorized to decrease infection risk and eliminate the issue of wear and tear seen on standard, reusable lenses. However, patient care would be compromised if the quality of images produced by the disposable lens were inferior to those produced by the reusable lens. The purpose of this study was to compare the quality of images produced by disposable versus standard gonioscopy lenses. A disposable single mirror lens (Sensor Medical Technology) and a standard Volk G-1 gonioscopy lens were used to image 21 volunteers who were prospectively recruited for the study. Images of the inferior and temporal angles of each subject's left eye were acquired using a slit-lamp camera through the disposable and standard gonioscopy lens. In total, 74 images were graded using the Spaeth gonioscopic system and for clarity and quality. Clarity was scored as 1 or 2 and defined as either (1) all structures perceived or (2) all structures not perceived. Quality was scored as 1, 2, or 3, and defined as (1) all angle landmarks clear and well focused, (2) some angle landmarks clear, others blurred, or (3) angle landmarks could not be ascertained. The 74 images were divided into images taken with the disposable single mirror lens and images taken with the standard Volk G-1 gonioscopy lens. The clarity and quality scores for each of these 2 image groups were averaged and P-values were calculated. Average quality of images produced with the standard lens was 1.46±0.56 compared with 1.54±0.61 for those produced with the disposable lens (P=0.55). Average clarity of images produced with the standard lens was 1.47±0.51 compared with 1.49±0.51 (P=0.90) with the disposable lens. We conclude that there is no significant difference in quality of images

The status of LILW disposal facility construction in Korea

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Min-Seok; Chung, Myung-Sub; Park, Kyu-Wan

2013-07-01

In this paper, we discuss the experiences during the construction of the first LILW disposal facility in South Korea. In December 2005, the South Korean Government designated Gyeongju-city as a host city of Low- and Intermediate-Level Radioactive Waste(LILW) disposal site through local referendums held in regions whose local governments had applied to host disposal facility in accordance with the site selection procedures. The LILW disposal facility is being constructed in Bongilri, Yangbuk-myeon, Gyeongju. The official name of the disposal facility is called 'Wolsong Low and Intermediate Level Radioactive Waste Disposal Center (LILW Disposal Center)'. It can dispose of 800,000 drumsmore » of radioactive wastes in a site of 2,100,000 square meters. At the first stage, LILW repository of underground silo type with disposal capacity of 100,000 drums is under construction expected to be completed by June of 2014. The Wolsong Low and Intermediate Level Radioactive Waste Disposal Center consists of surface facilities and underground facilities. The surface facilities include a reception and inspection facility, an interim storage facility, a radioactive waste treatment building, and supporting facilities such as main control center, equipment and maintenance shop. The underground facilities consist of a construction tunnel for transport of construction equipment and materials, an operation tunnel for transport of radioactive waste, an entrance shaft for workers, and six silos for final disposal of radioactive waste. As of Dec. 2012, the overall project progress rate is 93.8%. (authors)« less

Effects from past solid waste disposal practices.

PubMed Central

Johnson, L J; Daniel, D E; Abeele, W V; Ledbetter, J O; Hansen, W R

1978-01-01

This paper reviews documented environmental effects experience from the disposal of solid waste materials in the U.S. Selected case histories are discussed that illustrate waste migration and its actual or potential effects on human or environmental health. Principal conclusions resulting from this review were: solid waste materials do migrate beyond the geometric confines of the initial placement location; environmental effects have been experienced from disposal of municipal, agricultural, and toxic chemical wastes; and utilization of presently known science and engineering principles in sitting and operating solid waste disposal facilities would make a significant improvement in the containment capability of shallow land disposal facilities. PMID:367769

Radioactive waste disposal in the marine environment

NASA Astrophysics Data System (ADS)

Anderson, D. R.

In order to find the optimal solution to waste disposal problems, it is necessary to make comparisons between disposal media. It has become obvious to many within the scientific community that the single medium approach leads to over protection of one medium at the expense of the others. Cross media comparisons are being conducted in the Department of Energy ocean disposal programs for several radioactive wastes. Investigations in three areas address model development, comparisons of laboratory tests with field results and predictions, and research needs in marine disposal of radioactive waste. Tabulated data are included on composition of liquid high level waste and concentration of some natural radionuclides in the sea.

40 CFR 191.24 - Disposal standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Disposal standards. 191.24 Section 191.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL...

40 CFR 191.24 - Disposal standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Disposal standards. 191.24 Section 191.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL...

40 CFR 191.24 - Disposal standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Disposal standards. 191.24 Section 191.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL...

40 CFR 191.24 - Disposal standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Disposal standards. 191.24 Section 191.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL...

40 CFR 191.24 - Disposal standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Disposal standards. 191.24 Section 191.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL...

48 CFR 45.602-1 - Inventory disposal schedules.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Inventory disposal... CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Reutilization, and Disposal 45.602-1 Inventory disposal schedules. (a) Plant clearance officers should review and accept, or return for correction, inventory...

Daily disposable contact lens prescribing around the world.

PubMed

Efron, Nathan; Morgan, Philip B; Helland, Magne; Itoi, Motozumi; Jones, Deborah; Nichols, Jason J; van der Worp, Eef; Woods, Craig A

2010-10-01

Daily disposable contact lenses were introduced into the market 16 years ago. Data that we have gathered from annual contact lens fitting surveys conducted in Australia, Canada, Japan, The Netherlands, Norway, the UK and the USA between 2000 and 2008 indicates an overall increase in daily disposable lens fitting during this period. Daily disposable lenses are especially popular in Japan, Norway and the UK. There is a trend for these lenses to be fitted on a part-time basis. Males are over-represented in daily disposable lens fitting-a trend that is especially evident in Canada. Daily disposable lens wearers are about two years younger than wearers of reusable lenses in Japan and The Netherlands. The convenience and health benefits of daily disposable lenses are expected to fuel continued growth in this sector. Copyright (c) 2010 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

Safe disposal of surplus plutonium

NASA Astrophysics Data System (ADS)

Gong, W. L.; Naz, S.; Lutze, W.; Busch, R.; Prinja, A.; Stoll, W.

2001-06-01

About 150 tons of weapons grade and weapons usable plutonium (metal, oxide, and in residues) have been declared surplus in the USA and Russia. Both countries plan to convert the metal and oxide into mixed oxide fuel for nuclear power reactors. Russia has not yet decided what to do with the residues. The US will convert residues into a ceramic, which will then be over-poured with highly radioactive borosilicate glass. The radioactive glass is meant to provide a deterrent to recovery of plutonium, as required by a US standard. Here we show a waste form for plutonium residues, zirconia/boron carbide (ZrO 2/B 4C), with an unprecedented combination of properties: a single, radiation-resistant, and chemically durable phase contains the residues; billion-year-old natural analogs are available; and criticality safety is given under all conceivable disposal conditions. ZrO 2/B 4C can be disposed of directly, without further processing, making it attractive to all countries facing the task of plutonium disposal. The US standard for protection against recovery can be met by disposal of the waste form together with used reactor fuel.

Psychological impact of colostomy pouch change and disposal.

PubMed

McKenzie, Frances; White, Craig A; Kendall, Sally; Finlayson, Aileen; Urquhart, Mary; Williams, Isabel

This article presents some of the findings from a multicentre cross-sectional correlational study to evaluate the relationship between colostomy pouch change and disposal practices and the patient's psychological wellbeing. Five questionnaires were used in a one-off interview with 86 patients. Patients were assessed at between one and four months postoperatively. Results from the Pouch Change and Disposal questionnaire showed that only 25% of patients found disposal of used appliances the most difficult part of their pouch change and disposal routine. Half felt that their body was out of their control and 33% reported avoiding social and leisure activities due to what was involved in their pouch change and disposal routine. Patients cited several factors, such as minimizing odour and having an appliance that could flush away, as factors which would help them to stop avoiding these activities. Stoma care nurses have a unique opportunity to improve the psychological wellbeing of their patients by considering the aspects of pouch change and disposal that pose the greatest challenge to individuals. Use of a modified version of the Pouch Change and Disposal questionnaire may be a useful tool in identifying those at risk of impaired quality of life.

Crushing leads to waste disposal savings for FUSRAP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Darby, J.

1997-02-01

In this article the author discusses the application of a rock crusher as a means of implementing cost savings in the remediation of FUSRAP sites. Transportation and offsite disposal costs are at present the biggest cost items in the remediation of FUSRAP sites. If these debris disposal problems can be handled in different manners, then remediation savings are available. Crushing can result in the ability to handle some wastes as soil disposal problems, which have different disposal regulations, thereby permitting cost savings.

Lessons Learned from Radioactive Waste Storage and Disposal Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Esh, David W.; Bradford, Anna H.

2008-01-15

The safety of radioactive waste disposal facilities and the decommissioning of complex sites may be predicated on the performance of engineered and natural barriers. For assessing the safety of a waste disposal facility or a decommissioned site, a performance assessment or similar analysis is often completed. The analysis is typically based on a site conceptual model that is developed from site characterization information, observations, and, in many cases, expert judgment. Because waste disposal facilities are sited, constructed, monitored, and maintained, a fair amount of data has been generated at a variety of sites in a variety of natural systems. Thismore » paper provides select examples of lessons learned from the observations developed from the monitoring of various radioactive waste facilities (storage and disposal), and discusses the implications for modeling of future waste disposal facilities that are yet to be constructed or for the development of dose assessments for the release of decommissioning sites. Monitoring has been and continues to be performed at a variety of different facilities for the disposal of radioactive waste. These include facilities for the disposal of commercial low-level waste (LLW), reprocessing wastes, and uranium mill tailings. Many of the lessons learned and problems encountered provide a unique opportunity to improve future designs of waste disposal facilities, to improve dose modeling for decommissioning sites, and to be proactive in identifying future problems. Typically, an initial conceptual model was developed and the siting and design of the disposal facility was based on the conceptual model. After facility construction and operation, monitoring data was collected and evaluated. In many cases the monitoring data did not comport with the original site conceptual model, leading to additional investigation and changes to the site conceptual model and modifications to the design of the facility. The following cases are

12 CFR 615.5143 - Disposal of ineligible investments.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Disposal of ineligible investments. 615.5143... AFFAIRS, LOAN POLICIES AND OPERATIONS, AND FUNDING OPERATIONS Investment Management § 615.5143 Disposal of ineligible investments. You must dispose of an ineligible investment within 6 months unless we approve, in...

12 CFR 615.5143 - Disposal of ineligible investments.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AFFAIRS, LOAN POLICIES AND OPERATIONS, AND FUNDING OPERATIONS Investment Management § 615.5143 Disposal of ineligible investments. You must dispose of an ineligible investment within 6 months unless we approve, in... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Disposal of ineligible investments. 615.5143...

10 CFR 20.2108 - Records of waste disposal.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Records of waste disposal. 20.2108 Section 20.2108 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20.2108 Records of waste disposal. (a) Each licensee shall maintain records of the disposal of licensed materials made...

10 CFR 20.2108 - Records of waste disposal.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Records of waste disposal. 20.2108 Section 20.2108 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20.2108 Records of waste disposal. (a) Each licensee shall maintain records of the disposal of licensed materials made...

10 CFR 20.2108 - Records of waste disposal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Records of waste disposal. 20.2108 Section 20.2108 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20.2108 Records of waste disposal. (a) Each licensee shall maintain records of the disposal of licensed materials made...

10 CFR 20.2108 - Records of waste disposal.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Records of waste disposal. 20.2108 Section 20.2108 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20.2108 Records of waste disposal. (a) Each licensee shall maintain records of the disposal of licensed materials made...

10 CFR 20.2108 - Records of waste disposal.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Records of waste disposal. 20.2108 Section 20.2108 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Records § 20.2108 Records of waste disposal. (a) Each licensee shall maintain records of the disposal of licensed materials made...

12 CFR 571.83 - Disposal of consumer information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REPORTING Duties of Users of Consumer Reports Regarding Address Discrepancies and Records Disposal § 571.83 Disposal of consumer information. (a) Scope. This section applies to savings associations whose deposits... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Disposal of consumer information. 571.83...

12 CFR 334.83 - Disposal of consumer information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... GENERAL POLICY FAIR CREDIT REPORTING Duties of Users of Consumer Reports Regarding Address Discrepancies and Records Disposal § 334.83 Disposal of consumer information. (a) In general. You must properly... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Disposal of consumer information. 334.83...

12 CFR 334.83 - Disposal of consumer information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Disposal of consumer information. 334.83... GENERAL POLICY FAIR CREDIT REPORTING Duties of Users of Consumer Reports Regarding Address Discrepancies and Records Disposal § 334.83 Disposal of consumer information. (a) In general. You must properly...

12 CFR 571.83 - Disposal of consumer information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Disposal of consumer information. 571.83... REPORTING Duties of Users of Consumer Reports Regarding Address Discrepancies and Records Disposal § 571.83 Disposal of consumer information. (a) Scope. This section applies to savings associations whose deposits...

Crystalline and Crystalline International Disposal Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Viswanathan, Hari S.; Chu, Shaoping; Reimus, Paul William

2015-12-21

This report presents the results of work conducted between September 2014 and July 2015 at Los Alamos National Laboratory in the crystalline disposal and crystalline international disposal work packages of the Used Fuel Disposition Campaign (UFDC) for DOE-NE’s Fuel Cycle Research and Development program.

12 CFR 41.83 - Disposal of consumer information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Duties of Users of Consumer Reports Regarding Address Discrepancies and Records Disposal § 41.83 Disposal of consumer information. (a) Definitions as used in this section. (1) Bank means national banks... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Disposal of consumer information. 41.83 Section...

12 CFR 41.83 - Disposal of consumer information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Disposal of consumer information. 41.83 Section... Duties of Users of Consumer Reports Regarding Address Discrepancies and Records Disposal § 41.83 Disposal of consumer information. (a) Definitions as used in this section. (1) Bank means national banks...

29 CFR 1926.252 - Disposal of waste materials.

Code of Federal Regulations, 2014 CFR

2014-07-01

... fire regulations. (e) All solvent waste, oily rags, and flammable liquids shall be kept in fire... 29 Labor 8 2014-07-01 2014-07-01 false Disposal of waste materials. 1926.252 Section 1926.252..., Use, and Disposal § 1926.252 Disposal of waste materials. (a) Whenever materials are dropped more than...

R Factor-Controlled Restriction and Modification of Deoxyribonucleic Acid: Restriction Mutants

PubMed Central

Yoshimori, Robert; Roulland-Dussoix, Daisy; Boyer, Herbert W.

1972-01-01

Restriction mutants of two different R factor-controlled host specificities (RI and RII) were isolated. All of the restriction mutants examined had a normal modification phenotype. No complementation was observed between the RI and RII host specificities. It is concluded that for each host specificity no protein subunit is shared by the restriction endonuclease and modification methylase. PMID:4565538

50 CFR 27.94 - Disposal of waste.

Code of Federal Regulations, 2014 CFR

2014-10-01

... NATIONAL WILDLIFE REFUGE SYSTEM PROHIBITED ACTS Other Disturbing Violations § 27.94 Disposal of waste. (a) The littering, disposing, or dumping in any manner of garbage, refuse sewage, sludge, earth, rocks, or...

50 CFR 27.94 - Disposal of waste.

Code of Federal Regulations, 2012 CFR

2012-10-01

... NATIONAL WILDLIFE REFUGE SYSTEM PROHIBITED ACTS Other Disturbing Violations § 27.94 Disposal of waste. (a) The littering, disposing, or dumping in any manner of garbage, refuse sewage, sludge, earth, rocks, or...

50 CFR 27.94 - Disposal of waste.

Code of Federal Regulations, 2011 CFR

2011-10-01

... NATIONAL WILDLIFE REFUGE SYSTEM PROHIBITED ACTS Other Disturbing Violations § 27.94 Disposal of waste. (a) The littering, disposing, or dumping in any manner of garbage, refuse sewage, sludge, earth, rocks, or...

50 CFR 27.94 - Disposal of waste.

Code of Federal Regulations, 2013 CFR

2013-10-01

... NATIONAL WILDLIFE REFUGE SYSTEM PROHIBITED ACTS Other Disturbing Violations § 27.94 Disposal of waste. (a) The littering, disposing, or dumping in any manner of garbage, refuse sewage, sludge, earth, rocks, or...

Geotechnical engineering for ocean waste disposal. An introduction

USGS Publications Warehouse

Lee, Homa J.; Demars, Kenneth R.; Chaney, Ronald C.; ,

1990-01-01

As members of multidisciplinary teams, geotechnical engineers apply quantitative knowledge about the behavior of earth materials toward designing systems for disposing of wastes in the oceans and monitoring waste disposal sites. In dredge material disposal, geotechnical engineers assist in selecting disposal equipment, predict stable characteristics of dredge mounds, design mound caps, and predict erodibility of the material. In canister disposal, geotechnical engineers assist in specifying canister configurations, predict penetration depths into the seafloor, and predict and monitor canister performance following emplacement. With sewage outfalls, geotechnical engineers design foundation and anchor elements, estimate scour potential around the outfalls, and determine the stability of deposits made up of discharged material. With landfills, geotechnical engineers evaluate the stability and erodibility of margins and estimate settlement and cracking of the landfill mass. Geotechnical engineers also consider the influence that pollutants have on the engineering behavior of marine sediment and the extent to which changes in behavior affect the performance of structures founded on the sediment. In each of these roles, careful application of geotechnical engineering principles can contribute toward more efficient and environmentally safe waste disposal operations.

Fuzzy restrictions and an application to cooperative games with restricted cooperation

NASA Astrophysics Data System (ADS)

Gallardo, J. M.; Jiménez, N.; Jiménez-Losada, A.

2017-10-01

The concept of restriction, which is an extension of that of interior operator, was introduced to model limited cooperation in cooperative game theory. In this paper, a fuzzy version of restrictions is presented. We show that these new operators, called fuzzy restrictions, can be characterized by the transitivity of the fuzzy dependence relations that they induce. As an application, we introduce cooperative games with fuzzy restriction, which are used to model cooperative situations in which each player in a coalition has a level of cooperation within the coalition. A value for these games is defined and characterized.

Disposable Scholarship?

ERIC Educational Resources Information Center

Miller, Fredrick

2004-01-01

The digital materials that faculty produce for their classrooms often are saved only to storage devices that might become obsolete in a few years. Without an institutional effort to provide access systems, storage, and services for their digital media, are campuses in danger of creating "Disposable Scholarship"? In this article, the author…

Advances in Geologic Disposal System Modeling and Shale Reference Cases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mariner, Paul E.; Stein, Emily R.; Frederick, Jennifer M.

The Spent Fuel and Waste Science and Technology (SFWST) Campaign of the U.S. Department of Energy (DOE) Office of Nuclear Energy (NE), Office of Fuel Cycle Technology (OFCT) is conducting research and development (R&D) on geologic disposal of spent nuclear fuel (SNF) and high level nuclear waste (HLW). Two high priorities for SFWST disposal R&D are design concept development and disposal system modeling (DOE 2011, Table 6). These priorities are directly addressed in the SFWST Generic Disposal Systems Analysis (GDSA) work package, which is charged with developing a disposal system modeling and analysis capability for evaluating disposal system performance formore » nuclear waste in geologic media (e.g., salt, granite, shale, and deep borehole disposal).« less

Field Test to Evaluate Deep Borehole Disposal.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hardin, Ernest; Brady, Patrick Vane.; Clark, Andrew Jordan

The U.S. Department of Energy (DOE) has embarked on the Deep Borehole Field Test (DBFT), which will investigate whether conditions suitable for disposal of radioactive waste can be found at a depth of up to 5 km in the earth’s crust. As planned, the DBFT will demonstrate drilling and construction of two boreholes, one for initial scientific characterization, and the other at a larger diameter such as could be appropriate for waste disposal (the DBFT will not involve radioactive waste). A wide range of geoscience activities is planned for the Characterization Borehole, and an engineering demonstration of test package emplacementmore » and retrieval is planned for the larger Field Test Borehole. Characterization activities will focus on measurements and samples that are important for evaluating the long-term isolation capability of the Deep Borehole Disposal (DBD) concept. Engineering demonstration activities will focus on providing data to evaluate the concept’s operational safety and practicality. Procurement of a scientifically acceptable DBFT site and a site management contractor is now underway. The concept of deep borehole disposal (DBD) for radioactive wastes is not new. It was considered by the National Academy of Science (NAS 1957) for liquid waste, studied in the 1980’s in the U.S. (Woodward–Clyde 1983), and has been evaluated by European waste disposal R&D programs in the past few decades (for example, Grundfelt and Crawford 2014; Grundfelt 2010). Deep injection of wastewater including hazardous wastes is ongoing in the U.S. and regulated by the Environmental Protection Agency (EPA 2001). The DBFT is being conducted with a view to use the DBD concept for future disposal of smaller-quantity, DOE-managed wastes from nuclear weapons production (i.e., Cs/Sr capsules and granular solid wastes). However, the concept may also have broader applicability for nations that have a need to dispose of limited amounts of spent fuel from nuclear power reactors

Sewage Disposal in Port Harcourt, Nigeria.

ERIC Educational Resources Information Center

Ayotamuno, M. J.

1993-01-01

This survey of the Port Harcourt, Nigeria, sewage disposal system exemplifies sewage disposal in the developing world. Results reveal that some well-constructed and maintained drains, as well as many open drains and septic tanks, expose women and children to the possibility of direct contact with parasitic organisms and threaten water resources.…

Monte Carlo study of LDR seed dosimetry with an application in a clinical brachytherapy breast implant.

PubMed

Furstoss, C; Reniers, B; Bertrand, M J; Poon, E; Carrier, J-F; Keller, B M; Pignol, J P; Beaulieu, L; Verhaegen, F

2009-05-01

A Monte Carlo (MC) study was carried out to evaluate the effects of the interseed attenuation and the tissue composition for two models of 125I low dose rate (LDR) brachytherapy seeds (Medi-Physics 6711, IBt InterSource) in a permanent breast implant. The effect of the tissue composition was investigated because the breast localization presents heterogeneities such as glandular and adipose tissue surrounded by air, lungs, and ribs. The absolute MC dose calculations were benchmarked by comparison to the absolute dose obtained from experimental results. Before modeling a clinical case of an implant in heterogeneous breast, the effects of the tissue composition and the interseed attenuation were studied in homogeneous phantoms. To investigate the tissue composition effect, the dose along the transverse axis of the two seed models were calculated and compared in different materials. For each seed model, three seeds sharing the same transverse axis were simulated to evaluate the interseed effect in water as a function of the distance from the seed. A clinical study of a permanent breast 125I implant for a single patient was carried out using four dose calculation techniques: (1) A TG-43 based calculation, (2) a full MC simulation with realistic tissues and seed models, (3) a MC simulation in water and modeled seeds, and (4) a MC simulation without modeling the seed geometry but with realistic tissues. In the latter, a phase space file corresponding to the particles emitted from the external surface of the seed is used at each seed location. The results were compared by calculating the relevant clinical metrics V85, V100, and V200 for this kind of treatment in the target. D90 and D50 were also determined to evaluate the differences in dose and compare the results to the studies published for permanent prostate seed implants in literature. The experimental results are in agreement with the MC absolute doses (within 5% for EBT Gafchromic film and within 7% for TLD-100

Disposal of logging slash, thinnings, and brush by burying

Treesearch

Harry E Schimke; Ronald H. Dougherty

1966-01-01

A feasibility study was conducted on the Stanislaus National Forest to find out if logging slash, thinnings, and brush could be disposed of by burying. This method of slash disposal shows promise and has some distinct advantages over disposal by chipping and burning.

Disposable rabbit

DOEpatents

Lewis, Leroy C.; Trammell, David R.

1986-01-01

A disposable rabbit for transferring radioactive samples in a pneumatic transfer system comprises aerated plastic shaped in such a manner as to hold a radioactive sample and aerated such that dissolution of the rabbit in a solvent followed by evaporation of the solid yields solid waste material having a volume significantly smaller than the original volume of the rabbit.

Disposal rabbit

DOEpatents

Lewis, L.C.; Trammell, D.R.

1983-10-12

A disposable rabbit for transferring radioactive samples in a pneumatic transfer system comprises aerated plastic shaped in such a manner as to hold a radioactive sample and aerated such that dissolution of the rabbit in a solvent followed by evaporation of the solid yields solid waste material having a volume significantly smaller than the original volume of the rabbit.

Pathways for Disposal of Commercially-Generated Tritiated Waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halverson, Nancy V.

From a waste disposal standpoint, tritium is a major challenge. Because it behaves like hydrogen, tritium exchanges readily with hydrogen in the ground water and moves easily through the ground. Land disposal sites must control the tritium activity and mobility of incoming wastes to protect human health and the environment. Consequently, disposal of tritiated low-level wastes is highly regulated and disposal options are limited. The United States has had eight operating commercial facilities licensed for low-level radioactive waste disposal, only four of which are currently receiving waste. Each of these is licensed and regulated by its state. Only two ofmore » these sites accept waste from states outside of their specified regional compact. For waste streams that cannot be disposed directly at one of the four active commercial low-level waste disposal facilities, processing facilities offer various forms of tritiated low-level waste processing and treatment, and then transport and dispose of the residuals at a disposal facility. These processing facilities may remove and recycle tritium, reduce waste volume, solidify liquid waste, remove hazardous constituents, or perform a number of additional treatments. Waste brokers also offer many low-level and mixed waste management and transportation services. These services can be especially helpful for small-quantity tritiated-waste generators, such as universities, research institutions, medical facilities, and some industries. The information contained in this report covers general capabilities and requirements for the various disposal/processing facilities and brokerage companies, but is not considered exhaustive. Typically, each facility has extensive waste acceptance criteria and will require a generator to thoroughly characterize their wastes. Then a contractual agreement between the waste generator and the disposal/processing/broker entity must be in place before waste is accepted. Costs for tritiated waste

End of Life Disposal for Three Libration Point Missions through Manipulation of the Jacobi Constant and Zero Velocity Curves

NASA Technical Reports Server (NTRS)

Peterson, Jeremy D.; Brown, Jonathan M.

2015-01-01

The aim of this investigation is to determine the feasibility of mission disposal by inserting the spacecraft into a heliocentric orbit along the unstable manifold and then manipulating the Jacobi constant to prevent the spacecraft from returning to the Earth-Moon system. This investigation focuses around L1 orbits representative of ACE, WIND, and SOHO. It will model the impulsive delta-V necessary to close the zero velocity curves after escape through the L1 gateway in the circular restricted three body model and also include full ephemeris force models and higher fidelity finite maneuver models for the three spacecraft.

Sources of Radium Accumulation in Stream Sediments near Disposal Sites in Pennsylvania: Implications for Disposal of Conventional Oil and Gas Wastewater.

PubMed

Lauer, Nancy E; Warner, Nathaniel R; Vengosh, Avner

2018-02-06

In Pennsylvania, Appalachian oil and gas wastewaters (OGW) are permitted for release to surface waters after some treatment by centralized waste treatment (CWT) facilities. While this practice was largely discontinued in 2011 for unconventional Marcellus OGW at facilities permitted to release high salinity effluents, it continues for conventional OGW. This study aimed to evaluate the environmental implications of the policy allowing the disposal of conventional OGW. We collected stream sediments from three disposal sites receiving treated OGW between 2014 and 2017 and measured 228 Ra, 226 Ra, and their decay products, 228 Th and 210 Pb, respectively. We consistently found elevated activities of 228 Ra and 226 Ra in stream sediments in the vicinity of the outfall (total Ra = 90-25,000 Bq/kg) compared to upstream sediments (20-80 Bq/kg). In 2015 and 2017, 228 Th/ 228 Ra activity ratios in sediments from two disposal sites were relatively low (0.2-0.7), indicating that a portion of the Ra has accumulated in the sediments in recent (<3) years, when no unconventional Marcellus OGW was reportedly discharged. 228 Ra/ 226 Ra activity ratios were also higher than what would be expected solely from disposal of low 228 Ra/ 226 Ra Marcellus OGW. Based on these variations, we concluded that recent disposal of treated conventional OGW is the source of high Ra in stream sediments at CWT facility disposal sites. Consequently, policies pertaining to the disposal of only unconventional fluids are not adequate in preventing radioactive contamination in sediments at disposal sites, and the permission to release treated Ra-rich conventional OGW through CWT facilities should be reconsidered.

10 CFR 20.2008 - Disposal of certain byproduct material.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Disposal of certain byproduct material. 20.2008 Section 20.2008 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2008 Disposal of certain byproduct material. (a) Licensed material as defined in paragraphs (3...

10 CFR 20.2008 - Disposal of certain byproduct material.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Disposal of certain byproduct material. 20.2008 Section 20.2008 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2008 Disposal of certain byproduct material. (a) Licensed material as defined in paragraphs (3...

10 CFR 20.2008 - Disposal of certain byproduct material.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Disposal of certain byproduct material. 20.2008 Section 20.2008 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2008 Disposal of certain byproduct material. (a) Licensed material as defined in paragraphs (3...

10 CFR 20.2008 - Disposal of certain byproduct material.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Disposal of certain byproduct material. 20.2008 Section 20.2008 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2008 Disposal of certain byproduct material. (a) Licensed material as defined in paragraphs (3...

10 CFR 20.2008 - Disposal of certain byproduct material.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Disposal of certain byproduct material. 20.2008 Section 20.2008 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2008 Disposal of certain byproduct material. (a) Licensed material as defined in paragraphs (3...

Evaluation of Low-Level Waste Disposal Receipt Data for Los Alamos National Laboratory Technical Area 54, Area G Disposal Facility - Fiscal Year 2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

French, Sean B.; Shuman, Robert

2012-04-17

The Los Alamos National Laboratory (LANL or the Laboratory) generates radioactive waste as a result of various activities. Operational or institutional waste is generated from a wide variety of research and development activities including nuclear weapons development, energy production, and medical research. Environmental restoration (ER), and decontamination and decommissioning (D and D) waste is generated as contaminated sites and facilities at LANL undergo cleanup or remediation. The majority of this waste is low-level radioactive waste (LLW) and is disposed of at the Technical Area 54 (TA-54), Area G disposal facility. U.S. Department of Energy (DOE) Order 435.1 (DOE, 2001) requiresmore » that radioactive waste be managed in a manner that protects public health and safety, and the environment. To comply with this order, DOE field sites must prepare and maintain site-specific radiological performance assessments for LLW disposal facilities that accept waste after September 26, 1988. Furthermore, sites are required to conduct composite analyses that account for the cumulative impacts of all waste that has been (or will be) disposed of at the facilities and other sources of radioactive material that may interact with the facilities. Revision 4 of the Area G performance assessment and composite analysis was issued in 2008 (LANL, 2008). These analyses estimate rates of radionuclide release from the waste disposed of at the facility, simulate the movement of radionuclides through the environment, and project potential radiation doses to humans for several on-site and off-site exposure scenarios. The assessments are based on existing site and disposal facility data and on assumptions about future rates and methods of waste disposal. The accuracy of the performance assessment and composite analysis depends upon the validity of the data used and assumptions made in conducting the analyses. If changes in these data and assumptions are significant, they may invalidate

Military Throwaways Why Acquirers Should Go Disposable

DTIC Science & Technology

2016-02-01

Defense AT&L: January–February 2016 34 Military Throwaways? Why Acquirers Should Go Disposable Maj. Patrick Dugan, USAF Maj. Jon D. McComb...outdated they no longer are manufactured. Unfortunately, the military regularly deals with DMS issues. Going disposable would alleviate DMS concerns

When is a medicine unwanted, how is it disposed, and how might safe disposal be promoted? Insights from the Australian population.

PubMed

Bettington, Emilie; Spinks, Jean; Kelly, Fiona; Gallardo-Godoy, Alejandra; Nghiem, Son; Wheeler, Amanda J

2017-12-19

Objective The aim of the present study was to explore disposal practices of unwanted medicines in a representative sample of Australian adults, compare this with previous household waste surveys and explore awareness of the National Return and Disposal of Unwanted Medicines (RUM) Project. Methods A 10-min online survey was developed, piloted and conducted with an existing research panel of adult individuals. Survey questions recorded demographics, the presence of unwanted medicines in the home, medicine disposal practices and concerns about unwanted medicines. Descriptive statistical analyses and rank-ordered logit regression were conducted. Results Sixty per cent of 4302 respondents reported having unwanted medicines in their household. Medicines were primarily kept just in case they were needed again and one-third of these medicines were expired. Two-thirds of respondents disposed of medicines with the household garbage and approximately one-quarter poured medicines down the drain. Only 17.6% of respondents had heard of the RUM Project, although, once informed, 91.7% stated that they would use it. Respondents ranked the risk of unintended ingestion as the most important public health message for future social marketing campaigns. Conclusions Respondents were largely unaware of the RUM Project, yet were willing to use it once informed. Limited awareness could lead to environmental or public health risks, and targeted information campaigns are needed. What is known about the topic? There is a growing international evidence base on how people dispose of unwanted medicines and the negative consequences, particularly the environmental effects of inappropriate disposal. Although insight into variation in disposal methods is increasing, knowledge of how people perceive risks and awareness of inappropriate disposal methods is more limited. What does this paper add? This study provides evidence of inappropriate medicines disposal and potential stockpiling of medicines in

Draft Geologic Disposal Requirements Basis for STAD Specification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ilgen, Anastasia G.; Bryan, Charles R.; Hardin, Ernest

2015-03-25

This document provides the basis for requirements in the current version of Performance Specification for Standardized Transportation, Aging, and Disposal Canister Systems, (FCRD-NFST-2014-0000579) that are driven by storage and geologic disposal considerations. Performance requirements for the Standardized Transportation, Aging, and Disposal (STAD) canister are given in Section 3.1 of that report. Here, the requirements are reviewed and the rationale for each provided. Note that, while FCRD-NFST-2014-0000579 provides performance specifications for other components of the STAD storage system (e.g. storage overpack, transfer and transportation casks, and others), these have no impact on the canister performance during disposal, and are not discussedmore » here.« less

10 CFR 20.2006 - Transfer for disposal and manifests.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Transfer for disposal and manifests. 20.2006 Section 20.2006 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2006 Transfer for disposal and manifests. (a) The requirements of this section and appendix G to...

10 CFR 20.2006 - Transfer for disposal and manifests.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Transfer for disposal and manifests. 20.2006 Section 20.2006 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2006 Transfer for disposal and manifests. (a) The requirements of this section and appendix G to...

10 CFR 20.2006 - Transfer for disposal and manifests.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Transfer for disposal and manifests. 20.2006 Section 20.2006 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2006 Transfer for disposal and manifests. (a) The requirements of this section and appendix G to...

10 CFR 20.2006 - Transfer for disposal and manifests.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Transfer for disposal and manifests. 20.2006 Section 20.2006 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2006 Transfer for disposal and manifests. (a) The requirements of this section and appendix G to...

10 CFR 20.2006 - Transfer for disposal and manifests.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Transfer for disposal and manifests. 20.2006 Section 20.2006 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2006 Transfer for disposal and manifests. (a) The requirements of this section and appendix G to...

10 CFR 61.81 - Tests at land disposal facilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Tests at land disposal facilities. 61.81 Section 61.81 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Records, Reports, Tests, and Inspections § 61.81 Tests at land disposal facilities. (a) Each...

10 CFR 61.81 - Tests at land disposal facilities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Tests at land disposal facilities. 61.81 Section 61.81 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Records, Reports, Tests, and Inspections § 61.81 Tests at land disposal facilities. (a) Each...

10 CFR 61.81 - Tests at land disposal facilities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Tests at land disposal facilities. 61.81 Section 61.81 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Records, Reports, Tests, and Inspections § 61.81 Tests at land disposal facilities. (a) Each...

Site Selection for the Disposal of LLW in Taiwan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chuang, W.S.; Chi, L.M.; Tien, N.C.

2006-07-01

This paper presents the implementation status of the low-level radioactive waste (LLW) disposal program in Taiwan, including the disposal facility regulations, status of waste management, final disposal program, licensing procedures, waste acceptance criteria, site selection criteria and processes and preliminary disposal concepts. The first phase of site selection for low-level radioactive waste final disposal in Taiwan was implemented between 1992 and 2002. The site selection process adopted a Geographic Information System (GIS), Hierarchical Analysis System, Expert Evaluation System, and site reconnaissance. An incentive program for voluntary sites was also initiated. After a series of evaluations and discussion of 30 potentialmore » candidate sites, including 8 recommended sites, 5 qualified voluntary townships, and several remote uninhabited small islets, Hsiao-chiou islet was selected as the first priority candidate site in February 1998. The geological investigation work in Hsiao-chiou was conducted from March 1999 through October 2000. An Environmental Impact Statement Report (EIS) and the Investment Feasibility Study Report (IFS) were submitted to the Environmental Protection Agency (EPA) in November 2000 and to the Ministry of Economic Affairs (MOEA) in June 2001, respectively. Unfortunately, the site investigation was discontinued in 2002 due to political and public acceptance consideration. After years of planning, the second phase of the site selection process was launched in August 2004 and will be conducted through 2008. It is planned that a repository will be constructed in early 2009 and start to operate in 2014. The site selection process for the second phase is based on the earlier work and four potential candidate sites were selected for evaluation until 2005. A near surface disposal concept is proposed for a site located in the Taiwan strait, and cavern disposal concepts are proposed for three other sites located on the main island. This

32 CFR 176.45 - Disposal of buildings and property.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Disposal of buildings and property. 176.45... HOMELESS ASSISTANCE § 176.45 Disposal of buildings and property. (a) Puglic benefit transfer screening. Not... shall dispose of buildings and property in accordance with the record of decision or other decision...

41 CFR 301-76.2 - What is disposable pay?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What is disposable pay... What is disposable pay? Disposable pay is the part of the employee's compensation remaining after the... deductions such as savings bonds, charitable contributions, etc. Deductions may be made from any type of pay...

41 CFR 301-76.2 - What is disposable pay?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 4 2013-07-01 2012-07-01 true What is disposable pay? 301-76.2 Section 301-76.2 Public Contracts and Property Management Federal Travel Regulation System... What is disposable pay? Disposable pay is the part of the employee's compensation remaining after the...

Contamination of disposable tonometer prisms during tonometry.

PubMed

Rajak, S N; Paul, J; Sharma, V; Vickers, S

2006-03-01

Due to the theoretical possibility of prion transmission in applanation tonometry, many ophthalmological units in the United Kingdom now use disposable tonometer prisms. We have investigated the potential for bacterial and viral transmission from the health practitioner to the patient via disposable prisms. All staff who perform applanation tonometry at the Sussex Eye Hospital (SEH) received a questionnaire to evaluate if the applanating face of the prism is touched during tonometry and the ease of use of the disposable prism compared to the reusable prisms that were previously used. We then cultured prisms handled by a random sample of staff members for common bacteria. Finally, we constructed a model to investigate the possibility of interpatient adenoviral transmission via disposable tonometer prisms. The questionnaire revealed that almost 50% of the staff admit to touching the applanating face of the tonometer prism prior to applanation. Cultures of the prisms grew a range of bacteria including Staphylococcus epidermidis, Staphylococcus aureus, and Bacillus species. The viral model suggested that adenovirus could be transmitted by applanation tonometry. The use of disposable prisms for applanation tonometry may reduce the risk of prion transmission but is not bacteriologically or virologically aseptic. This is a potential infection risk to patients.

Syringe Disposal Among Injection Drug Users in San Francisco

PubMed Central

Martinez, Alexis N.; Carpenter, Lisa; Geckeler, Dara; Colfax, Grant; Kral, Alex H.

2011-01-01

To assess the prevalence of improperly discarded syringes and to examine syringe disposal practices of injection drug users (IDUs) in San Francisco, we visually inspected 1000 random city blocks and conducted a survey of 602 IDUs. We found 20 syringes on the streets we inspected. IDUs reported disposing of 13% of syringes improperly. In multivariate analysis, obtaining syringes from syringe exchange programs was found to be protective against improper disposal, and injecting in public places was predictive of improper disposal. Few syringes posed a public health threat. PMID:20466956

Geological considerations in hazardouswaste disposal

NASA Astrophysics Data System (ADS)

Cartwright, K.; Gilkeson, R. H.; Johnson, T. M.

1981-12-01

Present regulations assume that long-term isolation of hazardous wastes — including toxic chemical, biological, radioactive, flammable and explosive wastes — may be effected by disposal in landfills that have liners of very low hydraulic conductivity. In reality, total isolation of wastes in humid areas is not possible; some migration of leachate from wastes buried in the gound will always occur. Regulations should provide performance standards applicable on a site-by-site basis rather than rigid criteria for site selection and design. The performance standards should take into account several factors: (1) the categories, segregation, degradation and toxicity of the wastes; (2) the site hydrogeology, which governs the direction and rate of contaminant transport; (3) the attenuation of contaminants by geochemical interactions with geologic materials; and (4) the release rate of unattenuated pollutants to surface or groundwater. An adequate monitoring system is essential. The system should both test the extent to which the operation of the site meets performance standards and provide sufficient warning of pollution problems to allow implementation of remedial measures. In recent years there has been a trend away from numerous, small disposal sites toward fewer and larger sites. The size of a disposal site should be based on the attenuation capacity of the geologic material, which has a finite, though generally not well-defined, limit. For slowly degradable wastes, engineered sites with leachate-collection systems appear to be only a temporary solution since the leachate collected will also require final disposal.

Geological considerations in hazardouswaste disposal

USGS Publications Warehouse

Cartwright, K.; Gilkeson, R.H.; Johnson, T.M.

1981-01-01

Present regulations assume that long-term isolation of hazardous wastes - including toxic chemical, biological, radioactive, flammable and explosive wastes - may be effected by disposal in landfills that have liners of very low hydraulic conductivity. In reality, total isolation of wastes in humid areas is not possible; some migration of leachate from wastes buried in the gound will always occur. Regulations should provide performance standards applicable on a site-by-site basis rather than rigid criteria for site selection and design. The performance standards should take into account several factors: (1) the categories, segregation, degradation and toxicity of the wastes; (2) the site hydrogeology, which governs the direction and rate of contaminant transport; (3) the attenuation of contaminants by geochemical interactions with geologic materials; and (4) the release rate of unattenuated pollutants to surface or groundwater. An adequate monitoring system is essential. The system should both test the extent to which the operation of the site meets performance standards and provide sufficient warning of pollution problems to allow implementation of remedial measures. In recent years there has been a trend away from numerous, small disposal sites toward fewer and larger sites. The size of a disposal site should be based on the attenuation capacity of the geologic material, which has a finite, though generally not well-defined, limit. For slowly degradable wastes, engineered sites with leachate-collection systems appear to be only a temporary solution since the leachate collected will also require final disposal. ?? 1981.

9 CFR 50.18 - Identification and disposal of cattle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Identification and disposal of cattle... DESTROYED BECAUSE OF TUBERCULOSIS Dairy Cattle and Facilities in the El Paso, Texas, Region § 50.18 Identification and disposal of cattle. (a) All dairy cattle disposed of under this subpart must travel from the...

41 CFR 301-54.2 - What is disposable pay?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 4 2013-07-01 2012-07-01 true What is disposable pay? 301-54.2 Section 301-54.2 Public Contracts and Property Management Federal Travel Regulation System... BILLED TRAVEL CHARGE CARD General Rules § 301-54.2 What is disposable pay? Disposable pay is your...

40 CFR 35.6345 - Equipment disposal options.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Equipment disposal options. 35.6345 Section 35.6345 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL... options. The following disposal options are available: (a) Use the equipment on another CERCLA project and...

39 CFR 262.6 - Retention and disposal.

Code of Federal Regulations, 2013 CFR

2013-07-01

... of time between the creation of a series and its authorized disposal date; however, in some cases it... series that are maintained by components of the Postal Service; it provides maintenance, retention, transfer, and disposal instructions for each series listed, and serves as the authority for Postal...

39 CFR 262.6 - Retention and disposal.

Code of Federal Regulations, 2012 CFR

2012-07-01

... of time between the creation of a series and its authorized disposal date; however, in some cases it... series that are maintained by components of the Postal Service; it provides maintenance, retention, transfer, and disposal instructions for each series listed, and serves as the authority for Postal...

39 CFR 262.6 - Retention and disposal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... of time between the creation of a series and its authorized disposal date; however, in some cases it... series that are maintained by components of the Postal Service; it provides maintenance, retention, transfer, and disposal instructions for each series listed, and serves as the authority for Postal...

39 CFR 262.6 - Retention and disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... of time between the creation of a series and its authorized disposal date; however, in some cases it... series that are maintained by components of the Postal Service; it provides maintenance, retention, transfer, and disposal instructions for each series listed, and serves as the authority for Postal...

39 CFR 262.6 - Retention and disposal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... of time between the creation of a series and its authorized disposal date; however, in some cases it... series that are maintained by components of the Postal Service; it provides maintenance, retention, transfer, and disposal instructions for each series listed, and serves as the authority for Postal...

Disposal of spent fuel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blomeke, J O; Ferguson, D E; Croff, A G

1978-01-01

Based on preliminary analyses, spent fuel assemblies are an acceptable form for waste disposal. The following studies appear necessary to bring our knowledge of spent fuel as a final disposal form to a level comparable with that of the solidified wastes from reprocessing: 1. A complete systems analysis is needed of spent fuel disposition from reactor discharge to final isolation in a repository. 2. Since it appears desirable to encase the spent fuel assembly in a metal canister, candidate materials for this container need to be studied. 3. It is highly likely that some ''filler'' material will be needed betweenmore » the fuel elements and the can. 4. Leachability, stability, and waste-rock interaction studies should be carried out on the fuels. The major disadvantages of spent fuel as a disposal form are the lower maximum heat loading, 60 kW/acre versus 150 kW/acre for high-level waste from a reprocessing plant; the greater long-term potential hazard due to the larger quantities of plutonium and uranium introduced into a repository; and the possibility of criticality in case the repository is breached. The major advantages are the lower cost and increased near-term safety resulting from eliminating reprocessing and the treatment and handling of the wastes therefrom.« less

Gestational Protein Restriction Impairs Glucose Disposal in the Gastrocnemius Muscles of Female Rats

PubMed Central

Blesson, Chellakkan S.; Chinnathambi, Vijayakumar; Kumar, Sathish

2017-01-01

Gestational low-protein (LP) diet causes hyperglycemia and insulin resistance in adult offspring, but the mechanism is not clearly understood. In this study, we explored the role of insulin signaling in gastrocnemius muscles of gestational LP-exposed female offspring. Pregnant rats were fed a control (20% protein) or an isocaloric LP (6%) diet from gestational day 4 until delivery. Normal diet was given to mothers after delivery and to pups after weaning until necropsy. Offspring were euthanized at 4 months, and gastrocnemius muscles were treated with insulin ex vivo for 30 minutes. Messenger RNA and protein levels of molecules involved in insulin signaling were assessed at 4 months. LP females were smaller at birth but showed rapid catchup growth by 4 weeks. Glucose tolerance test in LP offspring at 3 months showed elevated serum glucose levels (P < 0.01; glycemia Δ area under the curve 342 ± 28 in LP vs 155 ± 23 in controls, mmol/L * 120 minutes) without any change in insulin levels. In gastrocnemius muscles, LP rats showed reduced tyrosine phosphorylation of insulin receptor substrate 1 upon insulin stimulation due to the overexpression of tyrosine phosphatase SHP-2, but serine phosphorylation was unaffected. Furthermore, insulin-induced phosphorylation of Akt, glycogen synthase kinase (GSK)–3α, and GSK-3β was diminished in LP rats, and they displayed an increased basal phosphorylation (inactive form) of glycogen synthase. Our study shows that gestational protein restriction causes peripheral insulin resistance by a series of phosphorylation defects in skeletal muscle in a mechanism involving insulin receptor substrate 1, SHP-2, Akt, GSK-3, and glycogen synthase causing dysfunctional GSK-3 signaling and increased stored glycogen, leading to distorted glucose homeostasis. PMID:28324067

Actual and estimated costs of disposable materials used during surgical procedures.

PubMed

Toyabe, Shin-Ichi; Cao, Pengyu; Kurashima, Sachiko; Nakayama, Yukiko; Ishii, Yuko; Hosoyama, Noriko; Akazawa, Kouhei

2005-07-01

It is difficult to estimate precisely the costs of disposable materials used during surgical operations. To evaluate the actual costs of disposable materials, we calculated the actual costs of disposable materials used in 59 operations by taking account of costs of all disposable materials used for each operation. The costs of the disposable materials varied significantly from operation to operation (US$ 38-4230 per operation), and the median [25-percentile and 75-percentile] of the sum total of disposable material costs of a single operation was found to be US$ 686 [205 and 993]. Multiple regression analysis with a stepwise regression method showed that costs of disposable materials significantly correlated only with operation time (p<0.001). Based on the results, we propose a simple method for estimating costs of disposable materials by measuring operation time, and we found that the method gives reliable results. Since costs of disposable materials used during surgical operations are considerable, precise estimation of the costs is essential for hospital cost accounting. Our method should be useful for planning hospital administration strategies.

Minimum dV for Targeted Spacecraft Disposal

NASA Technical Reports Server (NTRS)

Bacon, John B.

2017-01-01

The study analyzes the minimum capability required to dispose safely of a space object. The study considers 3- sigma environmental uncertainties, as well as spacecraft-specific constraints such as the available thrust, total impulse, the achievable increase or decrease in commandable frontal area under stable attitude (or stable tumble), and the final controllable altitude at which any such dV may be imparted. The study addresses the definition of the length and location of a 'safe' disposal area, which is a statistical manifestation of uncertainty in this process. Some general legal concerns are raised that are unique to this prospect of low dV disposals. Future work is summarized. The goal of such research is to improve public safety by creating optimally safe disposal strategies (and potentially, applicable regulations) for low-dV and/or low-thrust spacecraft that under more traditional strategies would need to be abandoned to fully-random decay with its inherent higher risk of human casualty.

Disposable telemetry cable deployment system

DOEpatents

Holcomb, David Joseph

2000-01-01

A disposable telemetry cable deployment system for facilitating information retrieval while drilling a well includes a cable spool adapted for insertion into a drill string and an unarmored fiber optic cable spooled onto the spool cable and having a downhole end and a stinger end. Connected to the cable spool is a rigid stinger which extends through a kelly of the drilling apparatus. A data transmission device for transmitting data to a data acquisition system is disposed either within or on the upper end of the rigid stinger.

Disposal of Kitchen Waste from High Rise Apartment

NASA Astrophysics Data System (ADS)

Ori, Kirki; Bharti, Ajay; Kumar, Sunil

2017-09-01

The high rise building has numbers of floor and rooms having variety of users or tenants for residential purposes. The huge quantities of heterogenous mixtures of domestic food waste are generated from every floor of the high rise residential buildings. Disposal of wet and biodegradable domestic kitchen waste from high rise buildings are more expensive in regards of collection and vertical transportation. This work is intended to address the technique to dispose of the wet organic food waste from the high rise buildings or multistory building at generation point with the advantage of gravity and vermicomposting technique. This innovative effort for collection and disposal of wet organic solid waste from high rise apartment is more economical and hygienic in comparison with present system of disposal.

Remote-Handled Low-Level Waste Disposal Project Code of Record

DOE Office of Scientific and Technical Information (OSTI.GOV)

Austad, S. L.; Guillen, L. E.; McKnight, C. W.

2015-04-01

The Remote-Handled Low-Level Waste (LLW) Disposal Project addresses an anticipated shortfall in remote-handled LLW disposal capability following cessation of operations at the existing facility, which will continue until it is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). Development of a new onsite disposal facility will provide necessary remote-handled LLW disposal capability and will ensure continuity of operations that generate remote-handled LLW. This report documents the Code of Record for design of a new LLW disposal capability. The report is owned by themore » Design Authority, who can authorize revisions and exceptions. This report will be retained for the lifetime of the facility.« less

41 CFR 301-54.2 - What is disposable pay?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What is disposable pay... BILLED TRAVEL CHARGE CARD General Rules § 301-54.2 What is disposable pay? Disposable pay is your..., etc. Deductions may be made from any type of pay you receive from your agency, e.g., basic pay...

Short-term response of subadult white sturgeon to hopper dredge disposal operations

USGS Publications Warehouse

Parsley, Michael J.; Popoff, Nicholas D.; Romine, Jason G.

2011-01-01

The effect of dredged-material disposal operations on the behavior of seven white sturgeon Acipenser transmontanus (50–101 cm fork length) was examined by analysis of the movements and depth use of these fish before, during, and after a series of hopper dredge disposal operations in the lower Columbia River. Analyses of fish locations showed that 12 flow-lane disposal operations within a 24-h period had minimal effect on subadult white sturgeon behavior; six of the seven fish showed slight attraction to the disposal area during disposals, and one fish increased its distance from the disposal area. The core area for all fish combined shifted toward the disposal area during disposals. In the 24 h after completion of the disposal operations the fish core areas shifted back toward those areas occupied before the disposals. The rates of movement, depths used, and diel movement patterns of the white sturgeon showed little change over all periods, suggesting that natural behaviors were not altered during and immediately after hopper dredge disposal operations.

49 CFR 599.201 - Identification of salvage auctions and disposal facilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... facilities. 599.201 Section 599.201 Transportation Other Regulations Relating to Transportation (Continued... and Disposal Facilities § 599.201 Identification of salvage auctions and disposal facilities. (a... disposal facility identified in paragraph (a)(2) or (a)(3) of this section. (2) A disposal facility listed...

Medications at School: Disposing of Pharmaceutical Waste

ERIC Educational Resources Information Center

Taras, Howard; Haste, Nina M.; Berry, Angela T.; Tran, Jennifer; Singh, Renu F.

2014-01-01

Background: This project quantified and categorized medications left unclaimed by students at the end of the school year. It determined the feasibility of a model medication disposal program and assessed school nurses' perceptions of environmentally responsible medication disposal. Methods: At a large urban school district all unclaimed…

36 CFR 13.1118 - Solid waste disposal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Section 13.1118 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Glacier Bay National Park and Preserve General Provisions § 13.1118 Solid waste disposal. (a) A solid waste disposal site may accept non-National Park...

36 CFR 13.1008 - Solid waste disposal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Section 13.1008 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Gates of the Arctic National Park and Preserve § 13.1008 Solid waste disposal. (a) A solid waste disposal site may accept non-National Park Service...

36 CFR 13.1118 - Solid waste disposal.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Section 13.1118 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Glacier Bay National Park and Preserve General Provisions § 13.1118 Solid waste disposal. (a) A solid waste disposal site may accept non-National Park...

Safety aspects of nuclear waste disposal in space

NASA Technical Reports Server (NTRS)

Rice, E. E.; Edgecombe, D. S.; Compton, P. R.

1981-01-01

Safety issues involved in the disposal of nuclear wastes in space as a complement to mined geologic repositories are examined as part of an assessment of the feasibility of nuclear waste disposal in space. General safety guidelines for space disposal developed in the areas of radiation exposure and shielding, containment, accident environments, criticality, post-accident recovery, monitoring systems and isolation are presented for a nuclear waste disposal in space mission employing conventional space technology such as the Space Shuttle. The current reference concept under consideration by NASA and DOE is then examined in detail, with attention given to the waste source and mix, the waste form, waste processing and payload fabrication, shipping casks and ground transport vehicles, launch site operations and facilities, Shuttle-derived launch vehicle, orbit transfer vehicle, orbital operations and space destination, and the system safety aspects of the concept are discussed for each component. It is pointed out that future work remains in the development of an improved basis for the safety guidelines and the determination of the possible benefits and costs of the space disposal option for nuclear wastes.

Up from the beach: medical waste disposal rules!

PubMed

Francisco, C J

1989-07-01

The recent incidents of floating debris, garbage, wood, and medical waste on our nation's beaches have focused public attention on waste management problems. The handling and disposal of solid waste remains a major unresolved national dilemma. Increased use of disposables by all consumers, including the medical profession, and the increasing costs of solid waste disposal options have aggravated the solid waste situation. Medical waste found on beaches in the summer of 1988 could have been generated by a number of sources, including illegal dumping; sewer overflow; storm water runoff; illegal drug users; and inadequate handling of solid waste at landfills and coastal transfer facilities, which receive waste from doctors' offices, laboratories, and even legitimate home users of syringes. As officials from New Jersey have determined, the beach garbage is no mystery. It's coming from you and me. In response to the perceived medical waste disposal problem, various state and federal agencies have adopted rules to regulate and control the disposal of medical waste. This article outlines the more significant rules that apply to medical waste.

5 CFR 300.604 - Restrictions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EMPLOYMENT (GENERAL) Time-In-Grade Restrictions § 300.604 Restrictions. The following time-in-grade restrictions must be met unless... may be advanced without time restriction to positions up to GS-5 if the position to be filled is no...

24 CFR 586.45 - Disposal of buildings and property.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Disposal of buildings and property... ASSISTANCE-COMMUNITY REDEVELOPMENT AND HOMELESS ASSISTANCE § 586.45 Disposal of buildings and property. (a... from HUD under § 586.35(c)(1) or § 586.35(d)(2), DoD shall dispose of buildings and property in...

Argillite And Crystalline Disposal Research: Accomplishments And Path-Forward.

DOE Office of Scientific and Technical Information (OSTI.GOV)

McMahon, Kevin A.; Jove-Colon, Carlos F.; Wang, Yifeng

The intention of this document is to provide a path-forward for research and development (R&D) for two host rock media-specific (argillite and crystalline) disposal research work packages within the Used Fuel Disposition Campaign (UFDC). The two work packages, Argillite Disposal R&D and Crystalline Disposal R&D, support the achievement of the overarching mission and objectives of the Department of Energy Office of Nuclear Energy Fuel Cycle Technologies Program. These two work packages cover many of the fundamental technical issues that will have multiple implications to other disposal research work packages by bridging knowledge gaps to support the development of the safetymore » case. The path-forward begins with the assumption of target dates that are set out in the January 2013 DOE Strategy for the Management and Disposal of Used Nuclear Fuel and High-Level Radioactive Waste (http://energy.gov/downloads/strategy-management-and-disposal-used-nuclear-fuel-and-high-levelradioactive- waste). The path-forward will be maintained as a living document and will be updated as needed in response to available funding and the progress of multiple R&D tasks in the Used Fuel Disposition Campaign and the Fuel Cycle Technologies Program. This path forward is developed based on the report of “Used Fuel Disposition Campaign Disposal Research and Development Roadmap (FCR&D-USED- 2011-000065 REV0)” (DOE, 2011). This document delineates the goals and objectives of the UFDC R&D program, needs for generic disposal concept design, and summarizes the prioritization of R&D issues.« less

A DECISION SUPPORT TOOL (DST) FOR DISPOSAL OF ...

EPA Pesticide Factsheets

Symposium Paper AFTER A BUILDING OR WATER TREATMENT/DISTRIBUTION FACILITY HAS GONE THROUGH DECONTAMINATION ACTIVITIES FOLLOWING A CONTAMINATION EVENT WITH CHEMICAL/BIOLOGICAL WARFARE AGENTS OR TOXIC INDUSTRIAL CHEMICAL, THERE WILL BE A SIGNIFICANT AMOUNT OF RESIDUAL MATERIAL AND WASTE TO BE DISPOSED. A CONTAMINATION EVENT COULD OCCUR FROM TERRORIST ACTIVITY OR FROM A NATURAL DISASTER SUCH AS THE RECENT HURRICANE EVENTS IN THE GULF COAST WHERE MOLD AND POLLUTANTS FROM DAMAGED CHEMICAL AND INDUSTRIAL FACILITIES HAVE RESULTED IN SIGNIFICANT QUANTITIES OF CONTAMINATED MATERIALS. IT iS LIKELY THAT MUCH OF THIS MATERIAL WILL BE DISPOSED OF IN PERMITTED LANDFILLS OR HIGH TEMPERATURE THERMAL INCINERATION FACILITIES. DATA HAS BEEN COLLECTED FROM THE OPEN LITERATURE, FROM STATE AND FEDERAL REGULATORY AGENCIES, AND FROM WASTE MANAGEMENT AND WATER UTILITY INDUSTRY STAKEHOLDER GROUPS, TO DEVELOP TECHNICAL GUIDANCE FOR DISPOSAL OF THESe RESIDUES. THE INFORMATION BECOMES AVAILABLE, AND OLD INFORMATION (SUCH AS CONTACT INFORMATION FOR KEY PERSONNEL) CHANGES. THE PRiMARY AUDIENCE FOR THIS TOOL WILL BE: 1) EMERGENCY RESPONSE AUTHORITIES WHO HAVE TO DECIDE THE MOST APPROPRIATE DECONTAMINATION METHODS AND DISPOSAL OF THE RESULTING RESIDUES; 2)STATE AND LOCAL PERMITTING AGENCIES, WHO HAVE TO MAKE DECISIONS ABOUT WHICH FACILITIES WILL BE ALLOWED TO DISPOSE OF THE MATERIALS: AND 3) THE WASTE MANAGEMENT AND WATER UTILITY INDUSTRY, THAT NEEDS TO SAFELY DISPOSE OF DECONTAMINATION RESIDUE

Disposal of medical waste: a legal perspective.

PubMed

Du Toit, Karen; Bodenstein, Johannes

2013-09-03

The Constitution of the Republic of South Africa provides that everyone has the right to an environment that is not harmful to their health and well-being. The illegal dumping of hazardous waste poses a danger to the environment when pollutants migrate into water sources and ultimately cause widespread infection or toxicity, endangering the health of humans who might become exposed to infection and toxins. To give effect to the Constitution, the safe disposal of hazardous waste is governed by legislation in South Africa. Reports of the illegal disposal of waste suggest a general lack of awareness and training in regard to the safe disposal of medical waste. 

Future trends which will influence waste disposal.

PubMed Central

Wolman, A

1978-01-01

The disposal and management of solid wastes are ancient problems. The evolution of practices naturally changed as populations grew and sites for disposal became less acceptable. The central search was for easy disposal at minimum costs. The methods changed from indiscriminate dumping to sanitary landfill, feeding to swine, reduction, incineration, and various forms of re-use and recycling. Virtually all procedures have disabilities and rising costs. Many methods once abandoned are being rediscovered. Promises for so-called innovations outstrip accomplishments. Markets for salvage vary widely or disappear completely. The search for conserving materials and energy at minimum cost must go on forever. PMID:570105

36 CFR 222.70 - Disposal of carcasses.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Section 222.70 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE RANGE MANAGEMENT Management of Wild Free-Roaming Horses and Burros § 222.70 Disposal of carcasses. Carcasses of animals that have lost their status as wild free-roaming horses or burros may be disposed of in any...

36 CFR 222.70 - Disposal of carcasses.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Section 222.70 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE RANGE MANAGEMENT Management of Wild Free-Roaming Horses and Burros § 222.70 Disposal of carcasses. Carcasses of animals that have lost their status as wild free-roaming horses or burros may be disposed of in any...

36 CFR 222.30 - Disposal of carcasses.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Section 222.30 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE RANGE MANAGEMENT Management of Wild Free-Roaming Horses and Burros § 222.30 Disposal of carcasses. Carcasses of animals that have lost their status as wild free-roaming horses or burros may be disposed of in any...

36 CFR 222.30 - Disposal of carcasses.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Section 222.30 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE RANGE MANAGEMENT Management of Wild Free-Roaming Horses and Burros § 222.30 Disposal of carcasses. Carcasses of animals that have lost their status as wild free-roaming horses or burros may be disposed of in any...

43 CFR 2743.4 - Patented disposal sites.

Code of Federal Regulations, 2013 CFR

2013-10-01

... that such land has been used for solid waste disposal or for any other purpose that the authorized... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Patented disposal sites. 2743.4 Section 2743.4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND...

43 CFR 2743.4 - Patented disposal sites.

Code of Federal Regulations, 2014 CFR

2014-10-01

... that such land has been used for solid waste disposal or for any other purpose that the authorized... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Patented disposal sites. 2743.4 Section 2743.4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND...

43 CFR 2743.4 - Patented disposal sites.

Code of Federal Regulations, 2012 CFR

2012-10-01

... that such land has been used for solid waste disposal or for any other purpose that the authorized... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Patented disposal sites. 2743.4 Section 2743.4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND...

Preliminary risk benefit assessment for nuclear waste disposal in space

NASA Technical Reports Server (NTRS)

Rice, E. E.; Denning, R. S.; Friedlander, A. L.; Priest, C. C.

1982-01-01

This paper describes the recent work of the authors on the evaluation of health risk benefits of space disposal of nuclear waste. The paper describes a risk model approach that has been developed to estimate the non-recoverable, cumulative, expected radionuclide release to the earth's biosphere for different options of nuclear waste disposal in space. Risk estimates for the disposal of nuclear waste in a mined geologic repository and the short- and long-term risk estimates for space disposal were developed. The results showed that the preliminary estimates of space disposal risks are low, even with the estimated uncertainty bounds. If calculated release risks for mined geologic repositories remain as low as given by the U.S. DOE, and U.S. EPA requirements continue to be met, then no additional space disposal study effort in the U.S. is warranted at this time. If risks perceived by the public are significant in the acceptance of mined geologic repositories, then consideration of space disposal as a complement to the mined geologic repository is warranted.

10 CFR 61.44 - Stability of the disposal site after closure.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Stability of the disposal site after closure. 61.44 Section 61.44 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.44 Stability of the disposal site after closure. The disposal...

10 CFR 61.44 - Stability of the disposal site after closure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Stability of the disposal site after closure. 61.44 Section 61.44 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.44 Stability of the disposal site after closure. The disposal...

10 CFR 61.44 - Stability of the disposal site after closure.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Stability of the disposal site after closure. 61.44 Section 61.44 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.44 Stability of the disposal site after closure. The disposal...

10 CFR 61.44 - Stability of the disposal site after closure.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Stability of the disposal site after closure. 61.44 Section 61.44 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.44 Stability of the disposal site after closure. The disposal...

10 CFR 61.44 - Stability of the disposal site after closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Stability of the disposal site after closure. 61.44 Section 61.44 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.44 Stability of the disposal site after closure. The disposal...

40 CFR 268.1 - Purpose, scope, and applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... identifies hazardous wastes that are restricted from land disposal and defines those limited circumstances under which an otherwise prohibited waste may continue to be land disposed. (b) Except as specifically..., storage, and disposal facilities. (c) Restricted wastes may continue to be land disposed as follows: (1...

40 CFR 268.1 - Purpose, scope, and applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... identifies hazardous wastes that are restricted from land disposal and defines those limited circumstances under which an otherwise prohibited waste may continue to be land disposed. (b) Except as specifically..., storage, and disposal facilities. (c) Restricted wastes may continue to be land disposed as follows: (1...

40 CFR 268.1 - Purpose, scope, and applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... identifies hazardous wastes that are restricted from land disposal and defines those limited circumstances under which an otherwise prohibited waste may continue to be land disposed. (b) Except as specifically..., storage, and disposal facilities. (c) Restricted wastes may continue to be land disposed as follows: (1...

40 CFR 268.1 - Purpose, scope, and applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... identifies hazardous wastes that are restricted from land disposal and defines those limited circumstances under which an otherwise prohibited waste may continue to be land disposed. (b) Except as specifically..., storage, and disposal facilities. (c) Restricted wastes may continue to be land disposed as follows: (1...

Release and disposal of materials during decommissioning of Siemens MOX fuel fabrication plant at Hanau, Germany

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koenig, Werner; Baumann, Roland

2007-07-01

In September 2006, decommissioning and dismantling of the Siemens MOX Fuel Fabrication Plant in Hanau were completed. The process equipment and the fabrication buildings were completely decommissioned and dismantled. The other buildings were emptied in whole or in part, although they were not demolished. Overall, the decommissioning process produced approximately 8500 Mg of radioactive waste (including inactive matrix material); clearance measurements were also performed for approximately 5400 Mg of material covering a wide range of types. All the equipment in which nuclear fuels had been handled was disposed of as radioactive waste. The radioactive waste was conditioned on the basismore » of the requirements specified for the projected German final disposal site 'Schachtanlage Konrad'. During the pre-conditioning, familiar processes such as incineration, compacting and melting were used. It has been shown that on account of consistently applied activity containment (barrier concept) during operation and dismantling, there has been no significant unexpected contamination of the plant. Therefore almost all the materials that were not a priori destined for radioactive waste were released without restriction on the basis of the applicable legal regulations (chap. 29 of the Radiation Protection Ordinance), along with the buildings and the plant site. (authors)« less

CCA-treated wood disposed in landfills and life-cycle trade-offs with waste-to-energy and MSW landfill disposal.

PubMed

Jambeck, Jenna; Weitz, Keith; Solo-Gabriele, Helena; Townsend, Timothy; Thorneloe, Susan

2007-01-01

Chromated copper arsenate (CCA)-treated wood is a preservative treated wood construction product that grew in use in the 1970s for both residential and industrial applications. Although some countries have banned the use of the product for some applications, others have not, and the product continues to enter the waste stream from construction, demolition and remodeling projects. CCA-treated wood as a solid waste is managed in various ways throughout the world. In the US, CCA-treated wood is disposed primarily within landfills; however some of the wood is combusted in waste-to-energy (WTE) facilities. In other countries, the predominant disposal option for wood, sometimes including CCA-treated wood, is combustion for the production of energy. This paper presents an estimate of the quantity of CCA-treated wood entering the disposal stream in the US, as well as an examination of the trade-offs between landfilling and WTE combustion of CCA-treated wood through a life-cycle assessment and decision support tool (MSW DST). Based upon production statistics, the estimated life span and the phaseout of CCA-treated wood, recent disposal projections estimate the peak US disposal rate to occur in 2008, at 9.7 million m(3). CCA-treated wood, when disposed with construction and demolition (C&D) debris and municipal solid waste (MSW), has been found to increase arsenic and chromium concentrations in leachate. For this reason, and because MSW landfills are lined, MSW landfills have been recommended as a preferred disposal option over unlined C&D debris landfills. Between landfilling and WTE for the same mass of CCA-treated wood, WTE is more expensive (nearly twice the cost), but when operated in accordance with US Environmental Protection Agency (US EPA) regulations, it produces energy and does not emit fossil carbon emissions. If the wood is managed via WTE, less landfill area is required, which could be an influential trade-off in some countries. Although metals are concentrated

50 CFR 27.94 - Disposal of waste.

Code of Federal Regulations, 2010 CFR

2010-10-01

... chemical wastes in, or otherwise polluting any waters, water holes, streams or other areas within any... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Disposal of waste. 27.94 Section 27.94... NATIONAL WILDLIFE REFUGE SYSTEM PROHIBITED ACTS Other Disturbing Violations § 27.94 Disposal of waste. (a...

Rapid Peptide Reagent Isolation in a Disposable Microfluidic Cartridge

DTIC Science & Technology

2010-09-01

Rapid Peptide Reagent Isolation in a Disposable Microfluidic Cartridge by Dimitra N. Stratis-Cullum, Joshua M. Kogot, and Paul M...Adelphi, MD 20783-1197 ARL-TR-5357 September 2010 Rapid Peptide Reagent Isolation in a Disposable Microfluidic Cartridge Dimitra N...Peptide Reagent Isolation in a Disposable Microfluidic Cartridge 5a. CONTRACT NUMBER DAAD19-03-D-004 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER

Disposable surgical face masks for preventing surgical wound infection in clean surgery.

PubMed

Vincent, Marina; Edwards, Peggy

2016-04-26

Surgical face masks were originally developed to contain and filter droplets containing microorganisms expelled from the mouth and nasopharynx of healthcare workers during surgery, thereby providing protection for the patient. However, there are several ways in which surgical face masks could potentially contribute to contamination of the surgical wound, e.g. by incorrect wear or by leaking air from the side of the mask due to poor string tension. To determine whether the wearing of disposable surgical face masks by the surgical team during clean surgery reduces postoperative surgical wound infection. In December 2015, for this seventh update, we searched: The Cochrane Wounds Specialised Register; The Cochrane Central Register of Controlled Trials; Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE and EBSCO CINAHL. We also searched the bibliographies of all retrieved and relevant publications. There were no restrictions with respect to language, date of publication or study setting. Randomised controlled trials (RCTs) and quasi-randomised controlled trials comparing the use of disposable surgical masks with the use of no mask. Two review authors extracted data independently. We included three trials, involving a total of 2106 participants. There was no statistically significant difference in infection rates between the masked and unmasked group in any of the trials. We identified no new trials for this latest update. From the limited results it is unclear whether the wearing of surgical face masks by members of the surgical team has any impact on surgical wound infection rates for patients undergoing clean surgery.

49 CFR 599.201 - Identification of salvage auctions and disposal facilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... on the Web site at http://www.cars.gov/disposal; or (3) A facility that disposes of vehicles in...) of this section, be currently listed on the Web site at http://www.cars.gov/disposal, as of the date.... (1) A disposal facility that qualifies as such by active membership in ELVS and that fails to...

49 CFR 599.201 - Identification of salvage auctions and disposal facilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

... on the Web site at http://www.cars.gov/disposal; or (3) A facility that disposes of vehicles in...) of this section, be currently listed on the Web site at http://www.cars.gov/disposal, as of the date.... (1) A disposal facility that qualifies as such by active membership in ELVS and that fails to...

49 CFR 599.201 - Identification of salvage auctions and disposal facilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... on the Web site at http://www.cars.gov/disposal; or (3) A facility that disposes of vehicles in...) of this section, be currently listed on the Web site at http://www.cars.gov/disposal, as of the date.... (1) A disposal facility that qualifies as such by active membership in ELVS and that fails to...

49 CFR 599.201 - Identification of salvage auctions and disposal facilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... on the Web site at http://www.cars.gov/disposal; or (3) A facility that disposes of vehicles in...) of this section, be currently listed on the Web site at http://www.cars.gov/disposal, as of the date.... (1) A disposal facility that qualifies as such by active membership in ELVS and that fails to...

Aquifer disposal of carbon dioxide for greenhouse effect mitigation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gupta, N.; Naymik, T.G.; Bergman, P.

1998-07-01

Deep aquifer sequestration of carbon dioxide (CO{sup 2}), generated from power plant and other industrial emissions, is being evaluated as one of the potential options for the reduction of atmospheric greenhouse gas emissions. The major advantages of using deep aquifers are that the disposal facilities may be located close to the sources, thus reducing the CO{sub 2} transport costs. The potential capacity is much larger than the projected CO{sub 2} emissions over the next century, and it is a long-term/permanent sequestration option, because a large portion of the injected CO{sub 2} may be fixed into the aquifer by dissolution ormore » mineralization. The major limitations include the potentially high cost, the risk of upward migration, and the public perception of risk. Most of the cost is due to the need to separate CO{sub 2} from other flue gases, rather than the actual cost of disposal. Hazardous liquid waste and acid gas disposal in deep sedimentary formations is a well-established practice. There are also numerous facilities for storage of natural gases in depleted oil and gas reservoirs. The only current facility for aquifer disposal of CO{sub 2} is the offshore injection well at Sleipner Vest in the North Sea in Norway operated by Statoil. Exxon and Pertamina are planning an offshore aquifer disposal facility at Natuna gas field in Indonesia. A major evaluation of the feasibility of CO{sub 2} disposal in the European Union and Norway has been conducted under project Joule II. The data and experience obtained from the existing deep-waste disposal facilities and from the Sleipner Vest site form a strong foundation for further research and development on CO{sub 2} sequestration. Federal Energy Technology Center (FETC) is currently leading a project that uses data from an existing hazardous waste disposal facility injecting in the Mt. Simon Sandstone aquifer in Ohio to evaluate hydrogeologic, geochemical, and social issues related to CO{sub 2} disposal.« less

Aquifer disposal of carbon dioxide for greenhouse effect mitigation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gupta, N.; Naymik, T.G.; Bergman, P.

1998-04-01

Deep aquifer sequestration of carbon dioxide (CO{sub 2}) generated from power plant and other industrial emissions, is being evaluated as one of the potential options for the reduction of atmospheric greenhouse gas emissions. The major advantages of using deep aquifers are that the disposal facilities may be located close to the sources, thus reducing the CO{sub 2} transport costs. The potential capacity is much larger than the projected CO{sub 2} emissions over the next century, and it is a long-term/permanent sequestration option, because a large portion of the injected CO{sub 2} may be fixed into the aquifer by dissolution ormore » mineralization. The major limitations include the potentially high cost, the risk of upward migration, and the public perception of risk. Most of the cost is due to the need to separate CO{sub 2} from other flue gases, rather than the actual cost of disposal. Hazardous liquid waste and acid gas disposal in deep sedimentary formations is a well-established practice. There are also numerous facilities for storage of natural gases in depleted oil and gas reservoirs. The only current facility for aquifer disposal of CO{sub 2} is the offshore injection well at Sleipner Vest in the North Sea in Norway operated by Statoil. Exxon and Pertamina are planning an offshore aquifer disposal facility at Natuna gas field in Indonesia. A major evaluation of the feasibility of CO{sub 2} disposal in the European Union and Norway has been conducted under project Joule II. The data and experience obtained from the existing deep-waste disposal facilities and from the Sleipner Vest site form a strong foundation for further research and development on CO{sub 2} sequestration. Federal Energy Technology Center (FETC) is currently leading a project that uses data from an existing hazardous waste disposal facility injecting in the Mt. Simon Sandstone aquifer in Ohio to evaluate hydrogeologic, geochemical, and social issues related to CO{sub 2} disposal.« less

Distribution of sewage indicated by Clostridium perfringens at a deep-water disposal site after cessation of sewage disposal.

PubMed

Hill, R T; Straube, W L; Palmisano, A C; Gibson, S L; Colwell, R R

1996-05-01

Clostridium perfringens, a marker of domestic sewage contamination, was enumerated in sediment samples obtained from the vicinity of the 106-Mile Site 1 month and 1 year after cessation of sewage disposal at this site. C. perfringens counts in sediments collected at the disposal site and from stations 26 nautical miles (ca. 48 km) and 50 nautical miles (ca. 92 km) to the southwest of the site were, in general, more than 10-fold higher than counts from an uncontaminated reference site. C. perfringens counts at the disposal site were not significantly different between 1992 and 1993, suggesting that sewage sludge had remained in the benthic environment at this site. At stations where C. perfringens counts were elevated (i.e., stations other than the reference station), counts were generally higher in the top 1 cm and decreased down to 5 cm. In some cases, C. perfringens counts in the bottom 4 or 5 cm showed a trend of higher counts in 1993 than in 1992, suggesting bioturbation. We conclude that widespread sludge contamination of the benthic environment has persisted for at least 1 year after cessation of ocean sewage disposal at the 106-Mile Site.

Wastewater Disposal Wells, Fracking, and Environmental Injustice in Southern Texas.

PubMed

Johnston, Jill E; Werder, Emily; Sebastian, Daniel

2016-03-01

To investigate race and poverty in areas where oil and gas wastewater disposal wells, which are used to permanently inject wastewater from hydraulic fracturing (fracking) operations, are permitted. With location data of oil and gas disposal wells permitted between 2007 and 2014 in the Eagle Ford area, a region of intensive fracking in southern Texas, we analyzed the racial composition of residents living less than 5 kilometers from a disposal well and those farther away, adjusting for rurality and poverty, using a Poisson regression. The proportion of people of color living less than 5 kilometers from a disposal well was 1.3 times higher than was the proportion of non-Hispanic Whites. Adjusting for rurality, disposal wells were 2.04 times (95% confidence interval = 2.02, 2.06) as common in areas with 80% people of color or more than in majority White areas. Disposal wells are also disproportionately sited in high-poverty areas. Wastewater disposal wells in southern Texas are disproportionately permitted in areas with higher proportions of people of color and residents living in poverty, a pattern known as "environmental injustice."

Wastewater Disposal Wells, Fracking, and Environmental Injustice in Southern Texas

PubMed Central

Werder, Emily; Sebastian, Daniel

2016-01-01

Objectives. To investigate race and poverty in areas where oil and gas wastewater disposal wells, which are used to permanently inject wastewater from hydraulic fracturing (fracking) operations, are permitted. Methods. With location data of oil and gas disposal wells permitted between 2007 and 2014 in the Eagle Ford area, a region of intensive fracking in southern Texas, we analyzed the racial composition of residents living less than 5 kilometers from a disposal well and those farther away, adjusting for rurality and poverty, using a Poisson regression. Results. The proportion of people of color living less than 5 kilometers from a disposal well was 1.3 times higher than was the proportion of non-Hispanic Whites. Adjusting for rurality, disposal wells were 2.04 times (95% confidence interval = 2.02, 2.06) as common in areas with 80% people of color or more than in majority White areas. Disposal wells are also disproportionately sited in high-poverty areas. Conclusions. Wastewater disposal wells in southern Texas are disproportionately permitted in areas with higher proportions of people of color and residents living in poverty, a pattern known as “environmental injustice.” PMID:26794166

Advances in poultry litter disposal technology--a review.

PubMed

Kelleher, B P; Leahy, J J; Henihan, A M; O'Dwyer, T F; Sutton, D; Leahy, M J

2002-05-01

The land disposal of waste from the poultry industry and subsequent environmental implications has stimulated interest into cleaner and more useful disposal options. The review presented here details advances in the three main alternative disposal routes for poultry litter, specifically in the last decade. Results of experimental investigations into the optimisation of composting, anaerobic digestion and direct combustion are summarised. These technologies open up increased opportunities to market the energy and nutrients in poultry litter to agricultural and non-agricultural uses. Common problems experienced by the current technologies are the existence and fate of nitrogen as ammonia, pH and temperature levels, moisture content and the economics of alternative disposal methods. Further advancement of these technologies is currently receiving increased interest, both academically and commercially. However, significant financial incentives are required to attract the agricultural industry.

Disposal of Unused Medicines: What You Should Know

MedlinePlus

... any potential risk to human health or the environment that may come from disposal by flushing. FDA continues to work with and encourage manufacturers of these medicines to develop alternative, safe disposal systems. Back to Table of Contents How ...

Disposal of radioactive iodine in space

NASA Technical Reports Server (NTRS)

Burns, R. E.; Defield, J. G.

1978-01-01

The possibility of space disposal of iodine waste from nuclear power reactors is investigated. The space transportation system utilized relies upon the space shuttle, a liquid hydrogen/liquid oxygen orbit transfer vehicle, and a solid propellant final stage. The iodine is assumed to be in the form of either an iodide or an iodate, and calculations assume that the final destination is either solar orbit or solar system escape. It is concluded that space disposal of iodine is feasible.

10 CFR 20.2003 - Disposal by release into sanitary sewerage.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Disposal by release into sanitary sewerage. 20.2003 Section 20.2003 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2003 Disposal by release into sanitary sewerage. (a) A licensee may discharge licensed...

10 CFR 20.2003 - Disposal by release into sanitary sewerage.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Disposal by release into sanitary sewerage. 20.2003 Section 20.2003 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2003 Disposal by release into sanitary sewerage. (a) A licensee may discharge licensed...

10 CFR 20.2003 - Disposal by release into sanitary sewerage.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Disposal by release into sanitary sewerage. 20.2003 Section 20.2003 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2003 Disposal by release into sanitary sewerage. (a) A licensee may discharge licensed...

10 CFR 20.2003 - Disposal by release into sanitary sewerage.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Disposal by release into sanitary sewerage. 20.2003 Section 20.2003 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2003 Disposal by release into sanitary sewerage. (a) A licensee may discharge licensed...

10 CFR 20.2003 - Disposal by release into sanitary sewerage.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Disposal by release into sanitary sewerage. 20.2003 Section 20.2003 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Waste Disposal § 20.2003 Disposal by release into sanitary sewerage. (a) A licensee may discharge licensed...

10 CFR 61.82 - Commission inspections of land disposal facilities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Commission inspections of land disposal facilities. 61.82 Section 61.82 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Records, Reports, Tests, and Inspections § 61.82 Commission inspections of land disposal...

10 CFR 61.82 - Commission inspections of land disposal facilities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Commission inspections of land disposal facilities. 61.82 Section 61.82 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Records, Reports, Tests, and Inspections § 61.82 Commission inspections of land disposal...

10 CFR 61.82 - Commission inspections of land disposal facilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Commission inspections of land disposal facilities. 61.82 Section 61.82 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Records, Reports, Tests, and Inspections § 61.82 Commission inspections of land disposal...

Disposal of children's stools and its association with childhood diarrhea in India.

PubMed

Bawankule, Rahul; Singh, Abhishek; Kumar, Kaushalendra; Pedgaonkar, Sarang

2017-01-05

Children's stool disposal is often overlooked in sanitation programs of any country. Unsafe disposal of children's stool makes children susceptible to many diseases that transmit through faecal-oral route. Therefore, the study aims to examine the magnitude of unsafe disposal of children's stools in India, the factors associated with it and finally its association with childhood diarrhea. Data from the third round of the National Family Health Survey (NFHS-3) conducted in 2005-06 is used to carry out the analysis. The binary logistic regression model is used to examine the factors associated with unsafe disposal of children's stool. Binary logistic regression is also used to examine the association between unsafe disposal of children's stool and childhood diarrhea. Overall, stools of 79% of children in India were disposed of unsafely. The urban-rural gap in the unsafe disposal of children's stool was wide. Mother's illiteracy and lack of exposure to media, the age of the child, religion and caste/tribe of the household head, wealth index, access to toilet facility and urban-rural residence were statistically associated with unsafe disposal of stool. The odds of diarrhea in children whose stools were disposed of unsafely was estimated to be 11% higher (95% CI: 1.01-1.21) than that of children whose stools were disposed of safely. An increase in the unsafe disposal of children's stool in the community also increased the risk of diarrhea in children. We found significant statistical association between children's stool disposal and diarrhea. Therefore, gains in reduction of childhood diarrhea can be achieved in India through the complete elimination of unsafe disposal of children's stools. The sanitation programmes currently being run in India must also focus on safe disposal of children's stool.

Composite analysis E-area vaults and saltstone disposal facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cook, J.R.

1997-09-01

This report documents the Composite Analysis (CA) performed on the two active Savannah River Site (SRS) low-level radioactive waste (LLW) disposal facilities. The facilities are the Z-Area Saltstone Disposal Facility and the E-Area Vaults (EAV) Disposal Facility. The analysis calculated potential releases to the environment from all sources of residual radioactive material expected to remain in the General Separations Area (GSA). The GSA is the central part of SRS and contains all of the waste disposal facilities, chemical separations facilities and associated high-level waste storage facilities as well as numerous other sources of radioactive material. The analysis considered 114 potentialmore » sources of radioactive material containing 115 radionuclides. The results of the CA clearly indicate that continued disposal of low-level waste in the saltstone and EAV facilities, consistent with their respective radiological performance assessments, will have no adverse impact on future members of the public.« less

21 CFR 876.5830 - Hemodialyzer with disposable insert (Kiil type).

Code of Federal Regulations, 2010 CFR

2010-04-01

... Hemodialyzer with disposable insert (Kiil type). (a) Identification. A hemodialyzer with disposable inserts (Kiil type) is a device that is used as a part of an artificial kidney system for the treatment of patients with renal failure or toxemic conditions and that includes disposable inserts consisting of layers...

Humboldt Open Ocean Disposal Site (HOODS) Survey Work 2014

EPA Pesticide Factsheets

The Humboldt Open Ocean Disposal Site (HOODS) is a dredged material disposal site located 3 nautical miles (nm) offshore of Humboldt Bay in Northern California. HOODS was permanently designated by EPA Region 9 in 1995, and has been actively used for dredged material disposal operations since then. The HOODS has received higher volumes of dredged material than predicted since its designation in 1995, mainly from USACE construction and maintenance dredging.

Macrobenthic succession following the cessation of sewage sludge disposal

NASA Astrophysics Data System (ADS)

Birchenough, Silvana N. R.; Frid, Chris L. J.

2009-11-01

Half a million tonnes of sewage sludge was disposed annually over an 18-yr period at a licensed area off the Northumberland coast, UK. The disposal operation ceased in December 1998, providing the ecological opportunity to study macrobenthic changes in relation to theoretical succession models. A transect from the centre of the disposal site to a control station was monitored three times a year (i.e. March, August and December). This study provides a description of the changes in the macrobenthos and physical environment in the initial '3 years' (i.e. 1999 - 2001). During the period of sewage sludge disposal there were indications of an impact on the macrobenthic community with a high total abundance of individuals ( N) and high total number of species ( S) at the stations located in the centre of the disposal ground. During the immediate post-disposal phase the site continued to show a localised increased of individuals and species in the disposal area. Over time the communities showed signs of successional changes when the reduction of organic matter source was eliminated from the natural system. Multivariate analysis demonstrated a clear gradient of change in the community composition between impacted and control stations. While most benthic studies assess re-colonisation and succession stages of macrobenthos by using manipulative field experiments, this study provides an in situ long-term assessment in the offshore environment. This study contributes with information on: i) initial colonization and succession of macrobenthic communities over a large scale and real world data; ii) macrobenthic data into existing successional models and iii) resilience of benthic communities following the cessation of sewage sludge disposal. This information has the potential to contribute to an effective management of the marine communities in the North Sea.

48 CFR 245.7204 - Preparing inventory disposal report.

Code of Federal Regulations, 2010 CFR

2010-10-01

... disposal report. 245.7204 Section 245.7204 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Special Instructions 245... any other activities having an interest in the inventory disposal. (c) Items on the form are self...

40 CFR 191.16 - Alternative provisions for disposal.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Alternative provisions for disposal. 191.16 Section 191.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR...

40 CFR 191.16 - Alternative provisions for disposal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Alternative provisions for disposal. 191.16 Section 191.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR...

40 CFR 191.16 - Alternative provisions for disposal.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Alternative provisions for disposal. 191.16 Section 191.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR...

40 CFR 191.16 - Alternative provisions for disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Alternative provisions for disposal. 191.16 Section 191.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR...

40 CFR 191.16 - Alternative provisions for disposal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Alternative provisions for disposal. 191.16 Section 191.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR...

40 CFR 61.154 - Standard for active waste disposal sites.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Standard for active waste disposal... for Asbestos § 61.154 Standard for active waste disposal sites. Each owner or operator of an active... visible emissions to the outside air from any active waste disposal site where asbestos-containing waste...

40 CFR 61.154 - Standard for active waste disposal sites.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 9 2013-07-01 2013-07-01 false Standard for active waste disposal... for Asbestos § 61.154 Standard for active waste disposal sites. Each owner or operator of an active... visible emissions to the outside air from any active waste disposal site where asbestos-containing waste...

40 CFR 61.154 - Standard for active waste disposal sites.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 9 2012-07-01 2012-07-01 false Standard for active waste disposal... for Asbestos § 61.154 Standard for active waste disposal sites. Each owner or operator of an active... visible emissions to the outside air from any active waste disposal site where asbestos-containing waste...

40 CFR 61.154 - Standard for active waste disposal sites.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standard for active waste disposal... for Asbestos § 61.154 Standard for active waste disposal sites. Each owner or operator of an active... visible emissions to the outside air from any active waste disposal site where asbestos-containing waste...

40 CFR 61.154 - Standard for active waste disposal sites.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 9 2014-07-01 2014-07-01 false Standard for active waste disposal... for Asbestos § 61.154 Standard for active waste disposal sites. Each owner or operator of an active... visible emissions to the outside air from any active waste disposal site where asbestos-containing waste...

40 CFR 761.63 - PCB household waste storage and disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false PCB household waste storage and..., AND USE PROHIBITIONS Storage and Disposal § 761.63 PCB household waste storage and disposal. PCB... to manage municipal or industrial solid waste, or in a facility with an approval to dispose of PCB...

Patients' Knowledge and Attitude toward the Disposal of Medications

PubMed Central

AlHamdan, Hani; Abualezz, Rayf; Bahadig, Faiz; Abonofal, Noha; Osman, Mohamed

2017-01-01

Background Safe disposal of medications is of high concern as malpractice may lead to harmful consequences such as undesirable effects, prescription drug abuse, overstocking, self-medication, accidental overdose, and even death. There is a lack of uniform and nationwide guidance on how patients should safely dispose their leftover medications. This study aims to assess patients' knowledge and attitude regarding the disposal of medications. Method This research is a cross-sectional study. A self-administered questionnaire was used to collect data from various outpatient pharmaceutical services in King Abdulaziz Medical City (KAMC), Jeddah. Results The study revealed that 73% of the respondents throw the medications in the trash, 14% return the medications to a pharmacy, 5% never dispose them, and 3% donate the medications to a friend or charity centers. More than 80% of the respondents never received any information or advice from healthcare providers about safe and proper disposal of medications. Conclusion Our findings suggest that there is an immediate requirement for the establishment of collaborative and uniform guidelines for the safe disposal of leftover medications. A policy for drug donation needs to be included in routine patient education as well as educational and collective programs for the public. PMID:29130019

33 CFR 334.293 - Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. 334.293 Section 334.293 Navigation and... RESTRICTED AREA REGULATIONS § 334.293 Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. (a) The area. (1) The waters within an area beginning at a point on the...

33 CFR 334.293 - Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. 334.293 Section 334.293 Navigation and... RESTRICTED AREA REGULATIONS § 334.293 Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. (a) The area. (1) The waters within an area beginning at a point on the...

33 CFR 334.293 - Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. 334.293 Section 334.293 Navigation and... RESTRICTED AREA REGULATIONS § 334.293 Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. (a) The area. (1) The waters within an area beginning at a point on the...

33 CFR 334.293 - Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. 334.293 Section 334.293 Navigation and... RESTRICTED AREA REGULATIONS § 334.293 Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. (a) The area. (1) The waters within an area beginning at a point on the...

33 CFR 334.293 - Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. 334.293 Section 334.293 Navigation and... RESTRICTED AREA REGULATIONS § 334.293 Elizabeth River, Craney Island Refueling Pier Restricted Area, Portsmouth VA; naval restricted area. (a) The area. (1) The waters within an area beginning at a point on the...

[Evidence-based management of medical disposable materials].

PubMed

Yang, Hai

2009-03-01

Evidence-based management of medical disposable materials pays attention to collect evidence comprehensively and systematically, accumulate and create evidence through its own work and also evaluate evidence strictly. This can be used as a function to guide out job. Medical disposable materials evidence system contains product register qualification, product quality certification, supplier's behavior, internal and external communication evidence. Managers can find different ways in creating and using evidence referring to specific inside and outside condition. Evidence-based management can help accelerating the development of management of medical disposable materials from traditional experience pattern to a systematic and scientific pattern. It also has the very important meaning to improve medical quality, control the unreasonable growth of medical expense and make purchase and supply chain be more efficient.

77 FR 14307 - Water and Waste Disposal Loans and Grants

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-09

... CFR 1777 RIN 0572-AC26 Water and Waste Disposal Loans and Grants AGENCY: Rural Utilities Service, USDA... pertaining to the Section 306C Water and Waste Disposal (WWD) Loans and Grants program, which provides water... to assist areas designated as colonias that lack access to water or waste disposal systems and/or...

32 CFR 644.381 - Disposal of buildings and other improvements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Disposal of buildings and other improvements. 644... Temporary Basis from Another Federal Agency § 644.381 Disposal of buildings and other improvements. Where... reimburse the Army for their net salvage value, or the buildings or improvements will be disposed of in...

Multi-Pack Disposal Concepts for Spent Fuel (Revision 1)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hardin, Ernest; Matteo, Edward N.; Hadgu, Teklu

2016-01-01

At the initiation of the Used Fuel Disposition (UFD) R&D campaign, international geologic disposal programs and past work in the U.S. were surveyed to identify viable disposal concepts for crystalline, clay/shale, and salt host media. Concepts for disposal of commercial spent nuclear fuel (SNF) and high-level waste (HLW) from reprocessing are relatively advanced in countries such as Finland, France, and Sweden. The UFD work quickly showed that these international concepts are all “enclosed,” whereby waste packages are emplaced in direct or close contact with natural or engineered materials . Alternative “open” modes (emplacement tunnels are kept open after emplacement formore » extended ventilation) have been limited to the Yucca Mountain License Application Design. Thermal analysis showed that if “enclosed” concepts are constrained by peak package/buffer temperature, that waste package capacity is limited to 4 PWR assemblies (or 9 BWR) in all media except salt. This information motivated separate studies: 1) extend the peak temperature tolerance of backfill materials, which is ongoing; and 2) develop small canisters (up to 4-PWR size) that can be grouped in larger multi-pack units for convenience of storage, transportation, and possibly disposal (should the disposal concept permit larger packages). A recent result from the second line of investigation is the Task Order 18 report: Generic Design for Small Standardized Transportation, Aging and Disposal Canister Systems. This report identifies disposal concepts for the small canisters (4-PWR size) drawing heavily on previous work, and for the multi-pack (16-PWR or 36-BWR).« less

Roadmap for disposal of Electrorefiner Salt as Transuranic Waste.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rechard, Robert P.; Trone, Janis R.; Kalinina, Elena Arkadievna

The experimental breeder reactor (EBR-II) used fuel with a layer of sodium surrounding the uranium-zirconium fuel to improve heat transfer. Disposing of EBR-II fuel in a geologic repository without treatment is not prudent because of the potentially energetic reaction of the sodium with water. In 2000, the US Department of Energy (DOE) decided to treat the sodium-bonded fuel with an electrorefiner (ER), which produces metallic uranium product, a metallic waste, mostly from the cladding, and the salt waste in the ER, which contains most of the actinides and fission products. Two waste forms were proposed for disposal in a minedmore » repository; the metallic waste, which was to be cast into ingots, and the ER salt waste, which was to be further treated to produce a ceramic waste form. However, alternative disposal pathways for metallic and salt waste streams may reduce the complexity. For example, performance assessments show that geologic repositories can easily accommodate the ER salt waste without treating it to form a ceramic waste form. Because EBR-II was used for atomic energy defense activities, the treated waste likely meets the definition of transuranic waste. Hence, disposal at the Waste Isolation Pilot Plant (WIPP) in southern New Mexico, may be feasible. This report reviews the direct disposal pathway for ER salt waste and describes eleven tasks necessary for implementing disposal at WIPP, provided space is available, DOE decides to use this alternative disposal pathway in an updated environmental impact statement, and the State of New Mexico grants permission.« less

48 CFR 53.301-1428 - Inventory Disposal Schedule.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Inventory Disposal Schedule. 53.301-1428 Section 53.301-1428 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Illustrations of Forms 53.301-1428 Inventory Disposal Schedule...

20 CFR 209.16 - Disposal of payroll records.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Disposal of payroll records. 209.16 Section 209.16 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT RAILROAD EMPLOYERS' REPORTS AND RESPONSIBILITIES § 209.16 Disposal of payroll records. Employers may...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

Draft Site Treatment Plan (DSTP), Volumes I and II

DOE Office of Scientific and Technical Information (OSTI.GOV)

D`Amelio, J.

1994-08-30

Site Treatment Plans (STP) are required for facilities at which the DOE generates or stores mixed waste. This Draft Site Treatment Plan (DSTP) the second step in a three-phase process, identifies the currently preferred options for treating mixed waste at the Savannah River Site (SRS) or for developing treatment technologies where technologies do not exist or need modification. The DSTP reflects site-specific preferred options, developed with the state`s input and based on existing available information. To the extent possible, the DSTP identifies specific treatment facilities for treating the mixed waste and proposes schedules. Where the selection of specific treatment facilitiesmore » is not possible, schedules for alternative activities such as waste characterization and technology assessment are provided. All schedule and cost information presented is preliminary and is subject to change. The DSTP is comprised of two volumes: this Compliance Plan Volume and the Background Volume. This Compliance Plan Volume proposes overall schedules with target dates for achieving compliance with the land disposal restrictions (LDR) of RCRA and procedures for converting the target dates into milestones to be enforced under the Order. The more detailed discussion of the options contained in the Background Volume is provided for informational purposes only.« less

The safe and responsible disposal of unused controlled drugs.

PubMed

Ahmed, Iftikhar; Majeed, Amer

There are well-defined legal requirements for the safe storage, handling and disposal of controlled drugs (CDs): The Misuse of Drugs Act 1971, and Safer Management of Controlled Drugs (Department of Health, 2007). Clinical staff involved in the prescription and administration of CDs to patients are responsible and accountable for the appropriate disposal of these drugs because of the risk of substance abuse. A review of current practice, as followed by staff involved in the use and disposal of CDs, has been evaluated in a multi-centre audit. This audit showed that a wide variation in attitude towards disposal of CDs exists among medical and non-medical staff, and that the sample hospitals are falling short of meeting proposed standards.

48 CFR 1404.805 - Disposal of contract files.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Disposal of contract files. 1404.805 Section 1404.805 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.805 Disposal of contract files. Disposition of files shall be...

48 CFR 1404.805 - Disposal of contract files.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Disposal of contract files. 1404.805 Section 1404.805 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.805 Disposal of contract files. Disposition of files shall be...

48 CFR 1404.805 - Disposal of contract files.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Disposal of contract files. 1404.805 Section 1404.805 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.805 Disposal of contract files. Disposition of files shall be...

48 CFR 1404.805 - Disposal of contract files.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Disposal of contract files. 1404.805 Section 1404.805 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.805 Disposal of contract files. Disposition of files shall be...

48 CFR 1404.805 - Disposal of contract files.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Disposal of contract files. 1404.805 Section 1404.805 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.805 Disposal of contract files. Disposition of files shall be...

Combination gas producing and waste-water disposal well

DOEpatents

Malinchak, Raymond M.

1984-01-01

The present invention is directed to a waste-water disposal system for use in a gas recovery well penetrating a subterranean water-containing and methane gas-bearing coal formation. A cased bore hole penetrates the coal formation and extends downwardly therefrom into a further earth formation which has sufficient permeability to absorb the waste water entering the borehole from the coal formation. Pump means are disposed in the casing below the coal formation for pumping the water through a main conduit towards the water-absorbing earth formation. A barrier or water plug is disposed about the main conduit to prevent water flow through the casing except for through the main conduit. Bypass conduits disposed above the barrier communicate with the main conduit to provide an unpumped flow of water to the water-absorbing earth formation. One-way valves are in the main conduit and in the bypass conduits to provide flow of water therethrough only in the direction towards the water-absorbing earth formation.

Advances in Geologic Disposal System Modeling and Application to Crystalline Rock

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mariner, Paul E.; Stein, Emily R.; Frederick, Jennifer M.

The Used Fuel Disposition Campaign (UFDC) of the U.S. Department of Energy (DOE) Office of Nuclear Energy (NE), Office of Fuel Cycle Technology (OFCT) is conducting research and development (R&D) on geologic disposal of used nuclear fuel (UNF) and high-level nuclear waste (HLW). Two of the high priorities for UFDC disposal R&D are design concept development and disposal system modeling (DOE 2011). These priorities are directly addressed in the UFDC Generic Disposal Systems Analysis (GDSA) work package, which is charged with developing a disposal system modeling and analysis capability for evaluating disposal system performance for nuclear waste in geologic mediamore » (e.g., salt, granite, clay, and deep borehole disposal). This report describes specific GDSA activities in fiscal year 2016 (FY 2016) toward the development of the enhanced disposal system modeling and analysis capability for geologic disposal of nuclear waste. The GDSA framework employs the PFLOTRAN thermal-hydrologic-chemical multi-physics code and the Dakota uncertainty sampling and propagation code. Each code is designed for massively-parallel processing in a high-performance computing (HPC) environment. Multi-physics representations in PFLOTRAN are used to simulate various coupled processes including heat flow, fluid flow, waste dissolution, radionuclide release, radionuclide decay and ingrowth, precipitation and dissolution of secondary phases, and radionuclide transport through engineered barriers and natural geologic barriers to the biosphere. Dakota is used to generate sets of representative realizations and to analyze parameter sensitivity.« less

Health hazards associated with solid waste disposal.

PubMed

Gaby, W L

1981-01-01

The landfilling and disposal of domestic solid waste should be considered as great or greater a public health hazard as raw sewage. Solid waste is toxic and contains a greater variety of pathogenic microorganisms than does sewage sludge. Of all the procedures for solid waste disposal, landfills have and will continue to give rise to serious public health problems of land and water pollution. Although the general public is opposed to landfilling our inept health officials have offered small communities and cities no choice. Small communities do not have the technical knowledge or the funds to initiate alternative procedures. As the volume of solid waste increases each year the magnitude of the health hazards will eventually force public health agencies to implement correct disposal procedures ultimately resulting in recycling.

36 CFR 262.5 - Disposal of purchased property.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Disposal of purchased... LAW ENFORCEMENT SUPPORT ACTIVITIES Rewards and Payments § 262.5 Disposal of purchased property. All evidence purchased under the authority of this subpart shall be maintained in accordance with all laws...

Removal and Disposal of An Environmental Carcinogen: Asbestos

ERIC Educational Resources Information Center

Fodero, Severio D.

1977-01-01

This article details the removal and disposal of asbestos ceiling material in a Yale University building. The removal process utilized a water and wetting agent technique used by firefighters and the debris disposal was in a sanitary landfill, following federal regulations for the handling of hazardous materials. (MA)

48 CFR 53.301-1424 - Inventory Disposal Report.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Inventory Disposal Report. 53.301-1424 Section 53.301-1424 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Illustrations of Forms 53.301-1424 Inventory Disposal Report. ER05AP04...

Nanomaterial disposal by incineration

EPA Science Inventory

As nanotechnology-based products enter into widespread use, nanomaterials will end up in disposal waste streams that are ultimately discharged to the environment. One possible end-of-life scenario is incineration. This review attempts to ascertain the potential pathways by which ...

10 CFR 61.62 - Funding for disposal site closure and stabilization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Section 61.62 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Financial Assurances § 61.62 Funding for disposal site closure and stabilization. (a) The... and stabilization, including: (1) Decontamination or dismantlement of land disposal facility...

10 CFR 61.62 - Funding for disposal site closure and stabilization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Section 61.62 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Financial Assurances § 61.62 Funding for disposal site closure and stabilization. (a) The... and stabilization, including: (1) Decontamination or dismantlement of land disposal facility...

10 CFR 61.62 - Funding for disposal site closure and stabilization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Section 61.62 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Financial Assurances § 61.62 Funding for disposal site closure and stabilization. (a) The... and stabilization, including: (1) Decontamination or dismantlement of land disposal facility...

10 CFR 61.62 - Funding for disposal site closure and stabilization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Section 61.62 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Financial Assurances § 61.62 Funding for disposal site closure and stabilization. (a) The... and stabilization, including: (1) Decontamination or dismantlement of land disposal facility...

10 CFR 61.62 - Funding for disposal site closure and stabilization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Section 61.62 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Financial Assurances § 61.62 Funding for disposal site closure and stabilization. (a) The... and stabilization, including: (1) Decontamination or dismantlement of land disposal facility...

Chemical Stockpile Disposal Program. Risk Analysis of the Disposal of Chemical Munitions at Regional or National Sites.

DTIC Science & Technology

1987-08-01

THE DISPOSAL OF CNEM.. CU) GA TECHNOLOGIES INC SRN DIEGO CA A H SARSELL ET AL. RUG 97 GA-C- i @563 UNLRSS FIED S APEO-CDE-IS- 9 ?SIGDRAA±5-85-D-822...F/ 15/.3 NL I ihhhhhhhhhhhhlm I fflfflffllfllfllfllf smhhhhhhhhhhh ~1.02 U.,5 A I *Pig- FiLE copy CHEMICAL STOCKPILE DISPOSAL PROGRAM RISK ANALYSIS...vr~. ’ . - a ’ a’ ’- . ,I1 - .V [ N- VW; W UU V. , U .U : , r ,,, - . ..... . SECURITY CLASSIFICATION OF THIS PAGE IM : I omApproved

Multi-pack Disposal Concepts for Spent Fuel (Rev. 0)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hadgu, Teklu; Hardin, Ernest; Matteo, Edward N.

2015-12-01

At the initiation of the Used Fuel Disposition (UFD) R&D campaign, international geologic disposal programs and past work in the U.S. were surveyed to identify viable disposal concepts for crystalline, clay/shale, and salt host media (Hardin et al., 2012). Concepts for disposal of commercial spent nuclear fuel (SNF) and high-level waste (HLW) from reprocessing are relatively advanced in countries such as Finland, France, and Sweden. The UFD work quickly showed that these international concepts are all “enclosed,” whereby waste packages are emplaced in direct or close contact with natural or engineered materials . Alternative “open” modes (emplacement tunnels are keptmore » open after emplacement for extended ventilation) have been limited to the Yucca Mountain License Application Design (CRWMS M&O, 1999). Thermal analysis showed that, if “enclosed” concepts are constrained by peak package/buffer temperature, waste package capacity is limited to 4 PWR assemblies (or 9-BWR) in all media except salt. This information motivated separate studies: 1) extend the peak temperature tolerance of backfill materials, which is ongoing; and 2) develop small canisters (up to 4-PWR size) that can be grouped in larger multi-pack units for convenience of storage, transportation, and possibly disposal (should the disposal concept permit larger packages). A recent result from the second line of investigation is the Task Order 18 report: Generic Design for Small Standardized Transportation, Aging and Disposal Canister Systems (EnergySolution, 2015). This report identifies disposal concepts for the small canisters (4-PWR size) drawing heavily on previous work, and for the multi-pack (16-PWR or 36-BWR).« less

Disposable condenser humidifiers in intensive care.

PubMed

Oh, T E; Thompson, W R; Hayward, D R

1981-11-01

Two disposable condenser humidifiers were evaluated in nine ventilated intensive care patients. The Portex "Humid Vent" delivered end-inspired absolute humidities of 22--26.3 g/m3 at end-inspired temperatures of 27--28.3 degrees C. Corresponding humidities and temperatures with the Servo "Humidifier 150" were higher and were constant, at 27.7--29 g/m3 and 29.3--29.7 degrees C respectively. These disposable devices can be used for humidification in intensive care, but only for patients breathing room air, or on a short term basis.

Project Execution Plan for the Remote Handled Low-Level Waste Disposal Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Danny Anderson

2014-07-01

As part of ongoing cleanup activities at the Idaho National Laboratory (INL), closure of the Radioactive Waste Management Complex (RWMC) is proceeding under the Comprehensive Environmental Response, Compensation, and Liability Act (42 USC 9601 et seq. 1980). INL-generated radioactive waste has been disposed of at RWMC since 1952. The Subsurface Disposal Area (SDA) at RWMC accepted the bulk of INL’s contact and remote-handled low-level waste (LLW) for disposal. Disposal of contact-handled LLW and remote-handled LLW ion-exchange resins from the Advanced Test Reactor in the open pit of the SDA ceased September 30, 2008. Disposal of remote-handled LLW in concrete disposalmore » vaults at RWMC will continue until the facility is full or until it must be closed in preparation for final remediation of the SDA (approximately at the end of fiscal year FY 2017). The continuing nuclear mission of INL, associated ongoing and planned operations, and Naval spent fuel activities at the Naval Reactors Facility (NRF) require continued capability to appropriately dispose of contact and remote handled LLW. A programmatic analysis of disposal alternatives for contact and remote-handled LLW generated at INL was conducted by the INL contractor in Fiscal Year 2006; subsequent evaluations were completed in Fiscal Year 2007. The result of these analyses was a recommendation to the Department of Energy (DOE) that all contact-handled LLW generated after September 30, 2008, be disposed offsite, and that DOE proceed with a capital project to establish replacement remote-handled LLW disposal capability. An analysis of the alternatives for providing replacement remote-handled LLW disposal capability has been performed to support Critical Decision-1. The highest ranked alternative to provide this required capability has been determined to be the development of a new onsite remote-handled LLW disposal facility to replace the existing remote-handled LLW disposal vaults at the SDA. Several

43 CFR 9265.5 - Non-sale disposals, general.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Non-sale disposals, general. 9265.5 Section 9265.5 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND... Vegetative Resources Management § 9265.5 Non-sale disposals, general. Commission of any of the acts listed in...

43 CFR 9265.5 - Non-sale disposals, general.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Non-sale disposals, general. 9265.5 Section 9265.5 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND... Vegetative Resources Management § 9265.5 Non-sale disposals, general. Commission of any of the acts listed in...

43 CFR 9265.5 - Non-sale disposals, general.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Non-sale disposals, general. 9265.5 Section 9265.5 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND... Vegetative Resources Management § 9265.5 Non-sale disposals, general. Commission of any of the acts listed in...

12 CFR 222.83 - Disposal of consumer information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... RESERVE SYSTEM FAIR CREDIT REPORTING (REGULATION V) Duties of Users of Consumer Reports Regarding Identity Theft § 222.83 Disposal of consumer information. (a) Definitions as used in this section. (1) You means... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Disposal of consumer information. 222.83...

How you spend your pennies ... factors affecting the efficiency of human waste disposal systems (re-usable and disposable) and their cost.

PubMed

Rollnick, M

1991-05-01

Both re-usable and disposable systems have their merits and problems. The disposable system, being fully integrated, appears to be steadily gaining market share compared with the re-usable system. Since its introduction, the success of the re-usable system has been limited by the use of pans not designed for automatic processing. Where the 'perfection' pan has been superseded by 'open' shaped receptacles and those used in commode chairs, cleaning effectiveness can be improved by a factor of 10. For this and other reasons, nursing involvement in the re-usable system can be high while the 'perfection' pan is in use. A work study exercise to compare nursing involvement in re-usable and disposable systems is under way. When selecting a human waste disposal system for any site, it is vital that all disciplines discuss and decide objectives. The equipment usage, space, site conditions, availability and quality of supplies (eg water, electricity), the costs of maintenance, nursing time and other expenditure must be considered. The disposable system is capable of high process rates (more than double that of the fastest re-usable system). Its capital cost is currently about 1,000 pounds less than an average re-usable system, but in the busiest wards, revenue costs may be higher. In such wards the space for disposable receptacle storage can be as much as five to ten times machine volume. The design of macerators is generally simpler (having less components) than washer-disinfectors. Monitoring and maintenance involvement are likewise expected to be lower, particularly in hospitals with modern drainage systems.(ABSTRACT TRUNCATED AT 250 WORDS)