Science.gov

Sample records for dissemination program progress

  1. Electric and magnetic fields research and public information dissemination program. Progress report

    SciTech Connect

    1995-12-01

    The Electric and Magnetic Fields (EMF) Research and Public Information Dissemination (RAPID) Program was authorized by the Energy Policy Act of 1992 (enacted October 24, 1992) to determine whether or not exposure to EMF produced by the generation, transmission, and use of electric energy affects human health. Two Federal agencies, the Department of Energy (DOE) and the National Institute of Environmental Health Sciences (NIEHS), have primary responsibility for the program, but other Federal agencies are key participants as well. This program requires that Federal appropriations be matched by contributions from non-Federal sources. The authorized level of funding for the program was $65 million over a 5-year period (fiscal years 1993-1997 inclusive). For EMF RAPID to be a fully funded program, $32.5 million over 5 years will have to be appropriated by Congress and matched by non-Federal contributions.

  2. Federal Assistance Program Quarterly Project Progress Report. Geothermal Energy Program: Information Dissemination, Public Outreach, and Technical Analysis Activities. Reporting Period: January 1 - March 31, 2001 [Final report

    SciTech Connect

    Lund, John W.

    2002-03-22

    The final report of the accomplishments of the geothermal energy program: information dissemination, public outreach and technical analysis activities by the project team consisting of the Geo-Heat Center, Geothermal Resources Council, Geothermal Education Office, Geothermal Energy Association and the Washington State University Energy Program.

  3. Creating new realities: program development and dissemination.

    PubMed Central

    Fixsen, D L; Blase, K A

    1993-01-01

    Program development and dissemination in human services present challenges and opportunities for social scientists. Over the past 27 years the Teaching-Family Model of group home treatment has moved from prototype development to widespread dissemination across North America. Reviewing concepts in industry related to product development and dissemination, the application of these concepts to a human services delivery system, and program replication and dissemination data offer information about how innovative human services can be widely adapted and adopted. PMID:8307838

  4. Dissemination of Educational Tools and Programs

    NASA Astrophysics Data System (ADS)

    Christian, C.

    1998-05-01

    The IDEAS program is oriented towards innovative approaches to education and therefore result in a wide range of programs including Astro Capella (the creation of a capella astronomy songs written and performed by a group from NASA/GSFC, Smale, Boyd, and Granger), video kiosks in the Air and Space Museum (SAO, Dow), teaching astronomy in the parks (U of Wisconsin, Bjorkman, Wilcots), as well as the more bread and butter programs of teacher training and curriculum development. In addition to describing some of the diverse programs to come out of the IDEAS programs, I will discuss the dissemination of the results of those programs, and especially the role of the broker/facilitator in that dissemination. The audience is invited to participate in this discussion.

  5. Chronic progressive disseminated histoplasmosis in a Mexican cockfighter.

    PubMed

    Flores-Franco, René Agustín; Gómez-Díaz, Antonio; de Jesús Fernández-Alonso, Antonio

    2015-01-01

    We present illustrative images from a Mexican 58-year-old man who had the occupation of cockfighting from childhood and presented with chronic progressive disseminated histoplasmosis with primarily cutaneous manifestations. © The American Society of Tropical Medicine and Hygiene.

  6. Chronic Progressive Disseminated Histoplasmosis in a Mexican Cockfighter

    PubMed Central

    Flores-Franco, René Agustín; Gómez-Díaz, Antonio; de Jesús Fernández-Alonso, Antonio

    2015-01-01

    We present illustrative images from a Mexican 58-year-old man who had the occupation of cockfighting from childhood and presented with chronic progressive disseminated histoplasmosis with primarily cutaneous manifestations. PMID:25568180

  7. Rapidly progressive quadriparesis heralding disseminated coccidioidomycosis in an immunocompetent patient.

    PubMed

    Tan, Lee A; Kasliwal, Manish K; Nag, Sukriti; O'Toole, John E; Traynelis, Vincent C

    2014-06-01

    Coccidioides species are dimorphic fungi endemic to southwestern USA and northern Mexico. Disseminated coccidioidomycosis is rare with an estimated incidence of 1% in affected individuals and usually presents as meningitis when the central nervous system is involved. Spinal involvement with coccidioidomycosis, though not uncommon, predominantly manifests as osseous involvement leading to osteomyelitis and epidural abscess formation. Progressive quadriparesis as a presenting symptom secondary to intramedullary spinal cord coccidioidomycosis is very unusual and to our knowledge has not been described. We report a patient with disseminated coccidioidomycosis who presented with rapidly progressive quadriparesis due to cervical intramedullary spinal cord involvement. The absence of known coccidioidomycosis with atypical clinical presentation made the diagnosis elusive, requiring emergent cervical laminectomies with dural biopsy for decompression of the spinal cord and confirmation of the diagnosis. The patient eventually succumbed to the progressive course of the disease. Although rare, disseminated coccidioidomycosis can present as new, rapidly progressing quadriparesis in patients who have traveled to endemic areas. A high index of suspicion in such patients with appropriately directed laboratory investigations and consideration of early biopsy might unravel the diagnosis facilitating early antifungal treatment with the potential to minimize morbidity and mortality associated with disseminated coccidioidomycosis. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Sharing Dissemination Responsibilities: A Guide for Articulating Vocational Education Disseminating Programs.

    ERIC Educational Resources Information Center

    Hull, William L.; Oldsen, Carl F.

    Designed for state vocational education Research Coordinating Units (RCU) personnel who manage dissemination programs, this guide offers suggestions for sharing dissemination responsibility with other state programs. The guide examines the possibilities of integrating activities in a horizontal dimension, i.e., across state educational agency…

  9. 45 CFR 1388.7 - Program criteria-dissemination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... best practices. (c) Specific target audiences must be identified for dissemination activities and... Affiliated Programs, and State service systems to disseminate information to target audiences. (e) The... of disabilities, and appropriate target audiences. (i) The UAP must contribute to the development of...

  10. A Dissemination Model for New Technical Education Programs. Final Report.

    ERIC Educational Resources Information Center

    Hull, Daniel M.

    The Technical Education Research Center-SW has conceived, tested, and refined a model for disseminating newly developed programs and materials throughout the nation. The model performed successfully in the dissemination of more than 50,000 educational units (modules) of Laser/Electro-Optics Technician (LEOT) materials during a four-year period…

  11. A Dissemination Model for New Technical Education Programs. Final Report.

    ERIC Educational Resources Information Center

    Hull, Daniel M.

    The Technical Education Research Center-SW has conceived, tested, and refined a model for disseminating newly developed programs and materials throughout the nation. The model performed successfully in the dissemination of more than 50,000 educational units (modules) of Laser/Electro-Optics Technician (LEOT) materials during a four-year period…

  12. 77 FR 22792 - Non-Competitive Program Expansion Supplement To Revise, Update, and Disseminate Educational...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... To Revise, Update, and Disseminate Educational Curricula Regarding Alzheimer's Disease and Related... Program Expansion Supplement To Revise, Update, and Disseminate Educational Curricula Regarding Alzheimer...) Program grantees to revise, update, and disseminate educational curricula regarding Alzheimer's...

  13. Exemplary Dissemination Programs for Intermediate Units Serving Rural Schools.

    ERIC Educational Resources Information Center

    Edington, Everett; Hays, Leonard

    Utilizing information derived from documents, site visits, correspondence, and personal interviews re: 6 intermediate education units serving rural schools which were initially identified via a mail survey, this report describes intermediate education units with exemplary information dissemination programs. Varying considerably, each program is…

  14. Recent Progress in Understanding Coxsackievirus Replication, Dissemination, and Pathogenesis

    PubMed Central

    Sin, Jon; Mangale, Vrushali; Thienphrapa, Wdee; Gottlieb, Roberta A.; Feuer, Ralph

    2015-01-01

    Coxsackieviruses (CVs) are relatively common viruses associated with a number of serious human diseases, including myocarditis and meningo-encephalitis. These viruses are considered cytolytic yet can persist for extended periods of time within certain host tissues requiring evasion from the host immune response and a greatly reduced rate of replication. A member of Picornaviridae family, CVs have been historically considered non-enveloped viruses – although recent evidence suggest that CV and other picornaviruses hijack host membranes and acquire an envelope. Acquisition of an envelope might provide distinct benefits to CV virions, such as resistance to neutralizing antibodies and efficient nonlytic viral spread. CV exhibits a unique tropism for progenitor cells in the host which may help to explain the susceptibility of the young host to infection and the establishment of chronic disease in adults. CVs have also been shown to exploit autophagy to maximize viral replication and assist in unconventional release from target cells. In this article, we review recent progress in clarifying virus replication and dissemination within the host cell, identifying determinants of tropism, and defining strategies utilized by the virus to evade the host immune response. Also, we will highlight unanswered questions and provide future perspectives regarding the potential mechanisms of CV pathogenesis. PMID:26142496

  15. Manual for Dissemination of Promising Program Models.

    ERIC Educational Resources Information Center

    Martin, Susan C.

    The Massachusetts Board of Education recently adopted a 5-year plan to assist Local Education Agencies (LEAs) in the curriculum areas of reading, writing, arithmetic, science, and computer literacy. However, reduction in funds and staff at the LEA level has decreased the ability of local programs to implement marketing and assistance. This manual,…

  16. Workplace Skills Enhancement Program. Dissemination Report.

    ERIC Educational Resources Information Center

    Essex Community Coll., MD.

    This document describes the Maryland Hospital Skills Enhancement Program, a collaborative effort of the Maryland Hospital Association, Essex Community College, and three Maryland hospitals that was designed to improve the literacy/basic education skills of hospital employees in 11 targeted service occupations. Two curriculum models were used:…

  17. Manual for Dissemination of Promising Program Models.

    ERIC Educational Resources Information Center

    Martin, Susan C.

    The Massachusetts Board of Education recently adopted a 5-year plan to assist Local Education Agencies (LEAs) in the curriculum areas of reading, writing, arithmetic, science, and computer literacy. However, reduction in funds and staff at the LEA level has decreased the ability of local programs to implement marketing and assistance. This manual,…

  18. Workplace Skills Enhancement Program. Dissemination Report.

    ERIC Educational Resources Information Center

    Martin Marietta Corp., Baltimore, MD.

    Essex Community College (ECC) implemented an onsite workplace literacy program for Martin Marietta (MM) employees with the cooperation of United Auto Workers (UAW) Local 738. Assisted by the working committees with representatives from all phases of the project, ECC and MM staff cooperated to develop a recruitment video, brochures, and…

  19. Evaluation Designs for the Improving Teaching Competencies Program Dissemination Strategies.

    ERIC Educational Resources Information Center

    Reinhard, Diane L.; And Others

    Evaluation designs are presented for these work components of the Improving Teaching Competencies Program (ITCP): (1) developing, implementing, and evaluating a strategy for disseminating selected ITCP instructional systems in Individually Guided Education (IGE) schools; (2) developing, implementing, and evaluating a strategy for disseminating…

  20. Progressive disseminated histoplasmosis presenting with cachexia and hypercalcemia

    PubMed Central

    Khasawneh, Faisal A; Ahmed, Subhan; Halloush, Ruba A

    2013-01-01

    Histoplasmosis is a common endemic mycosis. The majority of infections involving this dimorphic fungus are asymptomatic. Manifestations in symptomatic patients are diverse, ranging from flu-like illness to a more serious disseminated disease. We present here a case of chronic disseminated histoplasmosis mimicking a metastatic cancer. We reviewed the literature for cases of disseminated histoplasmosis presenting with hypercalcemia, focusing particularly on clinical presentation, risk factors predisposing for fungal infection, and outcome. We report a case of a 65-year-old diabetic male who presented with unexplained weight loss and hypercalcemia. Multiple brain space-occupying lesions and bilateral adrenal enlargement were evident on imaging studies. Biopsies showed caseating granulomas with budding yeast, consistent with histoplasmosis. The patient’s symptoms resolved after liposomal amphotericin B and itraconazole therapy. Granulomatous diseases, including fungal infections, should be considered alongside malignancies, in patients with similar presentation. PMID:23467543

  1. A Dissemination System for State Accountability Programs--Part 2: The Relationship of Contemporary Communication Theory to Accountability Dissemination Procedures.

    ERIC Educational Resources Information Center

    Bettinghaus, Erwin P.; Miller, Gerald R.

    An assumptive, theoretical, and empirical foundation for the development of a formal dissemination model to apply to the introduction of information about educational accountability programs is set forth. If a dissemination model is to be effective, the fundamental assumptions underlying it must be spelled out explicitly. Existing communication…

  2. Challenges and opportunities for promoting booster seat use: progressive dissemination of a high-threat message.

    PubMed

    Will, Kelli England; Dunaway, Krystall E; Kokorelis, Diane A; Sabo, Cynthia Shier; Lorek, Edward J

    2012-11-01

    Motivating parents to take certain safety precautions when traveling with their children remains challenging for advocates. Caregivers of booster-aged children are particularly difficult to reach because they do not consider their children to be of "safety-seat" age and have inherently low perceptions of vulnerability to crash injury. Unfortunately, most booster seat programs fail to adequately motivate their intended population because they are primarily informational in nature and rely on caregivers to seek out and attend to the information. In this article, interventions using threat appeal tactics and progressive dissemination methods are recommended to effectively target participation and perceptions of vulnerability among this population. Recent research on risk communication indicates that threat appeals are supported when they contain high threat and high efficacy components. Threat appeal tactics are particularly desirable when perception of vulnerability is low, as is the case with parents of booster-aged children. In addition to theoretical arguments for more aggressive intervention approaches, a case example is presented wherein such techniques were used to promote booster seat use. The intervention resulted in significant increases in knowledge, risk-reduction attitudes, sense of efficacy, and observed booster seat use. Through use of progressive dissemination methods, the intervention has reached an audience of 431,600 people and counting.

  3. Dissemination of Technology to Evaluate Healthy Food Incentive Programs.

    PubMed

    Freedman, Darcy A; Hunt, Alan R; Merritt, Katie; Shon, En-Jung; Pike, Stephanie N

    2017-03-01

    Federal policy supports increased implementation of monetary incentive interventions for chronic disease prevention among low-income populations. This study describes how a Prevention Research Center, working with a dissemination partner, developed and distributed technology to support nationwide implementation and evaluation of healthy food incentive programming focused on Supplemental Nutrition Assistance Program recipients. FM Tracks, an iOS-based application and website, was developed to standardize evaluation methods for healthy food incentive program implementation at direct-to-consumer markets. This evaluation examined diffusion and adoption of the technology over 9 months (July 2015-March 2016). Data were analyzed in 2016. FM Tracks was disseminated to 273 markets affiliated with 37 regional networks in 18 states and Washington, DC. All markets adopted the sales transaction data collection feature, with nearly all recording at least one Supplemental Nutrition Assistance Program (99.3%) and healthy food incentive (97.1%) transaction. A total of 43,493 sales transactions were recorded. By the ninth month of technology dissemination, markets were entering individual sales transactions using the application (34.5%) and website (29.9%) and aggregated transactions via website (35.6%) at similar rates. Use of optional evaluation features like recording a customer ID with individual transactions increased successively with a low of 22.2% during the first month to a high of 69.2% in the ninth month. Systematic and widely used evaluation technology creates possibilities for pragmatic research embedded within ongoing, real-world implementation of food access interventions. Technology dissemination requires supportive technical assistance and continuous refinement that can be advanced through academic-practitioner partnerships. Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  4. Development of a Model Dissemination Program for the Kentucky State Department of Education: State Dissemination Capacity Building Grant. Final Report.

    ERIC Educational Resources Information Center

    Sims, E. Norman

    Described in this report are the rationale, operation, results, and benefits of a 3-year project that developed a systematic dissemination program in the Kentucky State Department of Education. Aspects covered include program framework, administrative structure, components of the framework, procedures, expected and determined results, user…

  5. Progressive disseminated histoplasmosis in systemic lupus erythematosus-an unusual presentation of acute tenosynovitis and a literature review.

    PubMed

    Lim, Sian Yik; Kijsirichareanchai, Kunut; Winn, Richard

    2013-01-01

    Progressive disseminated histoplasmosis is a disease where Histoplasma capsulatum affects multiple organs due to the inability of host cellular immunity to control the infection. Progressive disseminated histoplasmosis mainly involves the bone marrow, liver, and lungs. We report an unusual initial presentation of progressive disseminated histoplasmosis presenting as acute tenosynovitis in a systemic lupus erythematosus (SLE) patient. This report highlights the point that H. capsulatum may present as focal lesions and a high level of suspicion is needed to make the diagnosis, especially in SLE patients. We specifically reviewed reported cases of progressive disseminated histoplasmosis in SLE patients, and a review of the literature is presented.

  6. 29 CFR 1960.12 - Dissemination of occupational safety and health program information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Dissemination of occupational safety and health program... OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED MATTERS Administration § 1960.12 Dissemination of occupational safety and health program information. (a) Copies of the Act, Executive Order 12196, program...

  7. 45 CFR 1388.7 - Program criteria-dissemination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... (a) Introduction to dissemination: The UAP disseminates information and research findings, including..., productivity, integration and inclusion of individuals with developmental disabilities and their families. (b) The UAP must be a resource for information for individuals with developmental disabilities and...

  8. 45 CFR 1388.7 - Program criteria-dissemination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... (a) Introduction to dissemination: The UAP disseminates information and research findings, including..., productivity, integration and inclusion of individuals with developmental disabilities and their families. (b... the knowledge base through publications and presentations, including those based on research...

  9. Program Evaluation: Strategies for Assessing How Information Dissemination Contributes to Agency Goals. Report to Congressional Committees.

    ERIC Educational Resources Information Center

    Kingsbury, Nancy

    Federal agencies use information dissemination programs as one of several tools to achieve various social or environmental goals. Evaluations of five federal information dissemination program cases were examined to assist agency efforts in evaluating and improving the effectiveness of such programs. These cases were: Environmental Protection…

  10. 29 CFR 1960.12 - Dissemination of occupational safety and health program information.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Dissemination of occupational safety and health program... HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED MATTERS Administration § 1960.12 Dissemination of...

  11. 29 CFR 1960.12 - Dissemination of occupational safety and health program information.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Dissemination of occupational safety and health program... HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED MATTERS Administration § 1960.12 Dissemination of...

  12. 29 CFR 1960.12 - Dissemination of occupational safety and health program information.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Dissemination of occupational safety and health program... HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED MATTERS Administration § 1960.12 Dissemination of...

  13. 29 CFR 1960.12 - Dissemination of occupational safety and health program information.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Dissemination of occupational safety and health program... HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED MATTERS Administration § 1960.12 Dissemination of...

  14. 29 CFR 90.22 - Dissemination of program knowledge and assistance to workers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Dissemination of program knowledge and assistance to workers. 90.22 Section 90.22 Labor Office of the Secretary of Labor CERTIFICATION OF ELIGIBILITY TO APPLY FOR... the Subject of an Investigation for Industry Import Relief § 90.22 Dissemination of program...

  15. 29 CFR 90.22 - Dissemination of program knowledge and assistance to workers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Dissemination of program knowledge and assistance to workers. 90.22 Section 90.22 Labor Office of the Secretary of Labor CERTIFICATION OF ELIGIBILITY TO APPLY FOR... the Subject of an Investigation for Industry Import Relief § 90.22 Dissemination of program knowledge...

  16. Reinterpreting Dissemination of Prevention Programs as Widespread Implementation with Effectiveness and Fidelity.

    ERIC Educational Resources Information Center

    Elias, Maurice J.

    This article urges a reexamination of the concept of dissemination of health-related prevention programs. The article discusses factors that serve as sustaining conditions for dissemination of prevention programs including: (1) the nature of preventive intervention and parameters of effective community-based prevention praxis; (2) aspects of the…

  17. Reinterpreting Dissemination of Prevention Programs as Widespread Implementation with Effectiveness and Fidelity.

    ERIC Educational Resources Information Center

    Elias, Maurice J.

    This article urges a reexamination of the concept of dissemination of health-related prevention programs. The article discusses factors that serve as sustaining conditions for dissemination of prevention programs including: (1) the nature of preventive intervention and parameters of effective community-based prevention praxis; (2) aspects of the…

  18. Wind Energy Program: Information Dissemination and Outreach Final Report

    SciTech Connect

    Bradley G. Stevens, P.E.; Troy K. Simonsen

    2003-07-15

    OAK B188 This project was funded by the U.S. Department of Energy (DOE) under the Office of Energy Efficiency and Renewable Energy's Fiscal Year 2000 Broad-Based Solicitation on Information Dissemination and Outreach--Program Area of Interest 1A. The project was initiated with a kickoff meeting on August 30, 2000, at the National Renewal Energy Laboratory (NREL) facility in Golden, Colorado. Energy and Environmental Research Center (EERC) personnel met with DOE and NREL representatives to review project objectives and participant goals. As proposed, the goal of the DOE-funded program was to develop a center of excellence for wind energy focused on the central and northern Great Plains region, which later became known as the Plains Organization for Wind Energy Resources (POWER). The POWER focus area was originally defined as North Dakota, Minnesota, South Dakota, and Iowa, but soon expanded to also include Kansas, Montana, Nebraska, and Oklahoma. Although this definition of the POWER region is not rigid, it does represent most of the primary wind resource states. All of these, except for Iowa and Minnesota, have had lesser wind energy development than other parts of the country. Under this Cooperative Agreement, the POWER Program established a regional wind energy center, providing objective educational, technical, and partnership-building resources for developing the vast wind resources in the central and northern Great Plains region. POWER activities were performed under the following task structure: Task 1--Internet Web Site/Database Development Task 2--Resource Assessment Task 3--Education and Workshops Task 4--Training Task 5--Development and Demonstration of Wind Technologies

  19. Progressive disseminated histoplasmosis mimicking a flare of systemic lupus erythematosus: a European case report

    PubMed Central

    Peters, E. J.; van Vugt, R. M.; van der Spoel, J. I.; van Dijk, K.

    2016-01-01

    Introduction: Diagnosing progressive disseminated histoplasmosis (PDH) in patients with systemic lupus erythematosus (SLE) is diagnostically challenging. Since PDH is lethal when untreated, awareness of this infection in patients with SLE is of utmost importance. To the best of our knowledge, this is the first description of a case of PDH in a patient with SLE in Europe. Case presentation: A 56-year-old woman of Surinamese descent with a history of SLE, presented with fever and polyarthritis. Although a flare of SLE was suspected initially, cultures of bone marrow and broncho-alveolar lavage fluid grew Histoplasma capsulatum. Conclusion: This case report highlights that physicians should be aware of progressive disseminated histoplasmosis in patients with SLE treated with immunosuppressive agents. The signs and symptoms can easily mimic a SLE flare, which would then be treated with more aggressive immunosuppression. Failure to recognize the infection will therefore invariably lead to death of the patient. Progressive disseminated histoplasmosis is usually not recognized by doctors in non-endemic areas such as Europe. However, globalisation and more frequent intercontinental traffic of immunocompromised patients currently increases the incidence of histoplasmosis in these areas. It is therefore of life-saving importance that doctors are aware of the features of the infection in areas where H. capsulatum is not endemic. PMID:28348765

  20. Oral administration of FAK inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal cancer

    SciTech Connect

    Hao, Hui-fang; Takaoka, Munenori; Bao, Xiao-hong; Wang, Zhi-gang; Tomono, Yasuko; Sakurama, Kazufumi; Ohara, Toshiaki; Fukazawa, Takuya; Yamatsuji, Tomoki; Fujiwara, Toshiyoshi; Naomoto, Yoshio

    2012-07-13

    Highlights: Black-Right-Pointing-Pointer A novel FAK inhibitor TAE226 suppressed FAK activity in HCT116 colon cancer cells. Black-Right-Pointing-Pointer TAE226 suppressed proliferation and migration, with a modest effect on adhesion. Black-Right-Pointing-Pointer Silencing of FAK by siRNA made no obvious difference on cancer cell attachment. Black-Right-Pointing-Pointer TAE226 treatment suppressed the progression of peritoneal dissemination. Black-Right-Pointing-Pointer Oral administration of TAE226 prolonged the survival of tumor-bearing mice. -- Abstract: Peritoneal dissemination is one of the most terrible types of colorectal cancer progression. Focal adhesion kinase (FAK) plays a crucial role in the biological processes of cancer, such as cell attachment, migration, proliferation and survival, all of which are essential for the progression of peritoneal dissemination. Since we and other groups have reported that the inhibition of FAK activity exhibited a potent anticancer effect in several cancer models, we hypothesized that TAE226, a novel ATP-competitive tyrosine kinase inhibitor designed to target FAK, can prevent the occurrence and progression of peritoneal dissemination. In vitro, TAE226 greatly inhibited the proliferation and migration of HCT116 colon cancer cells, while their adhesion on the matrix surface was minimally inhibited when FAK activity and expression was suppressed by TAE226 and siRNA. In vivo, when HCT116 cells were intraperitoneally inoculated in mice, the cells could attach to the peritoneum and begin to grow within 24 h regardless of the pretreatment of cells with TAE226 or FAK-siRNA, suggesting that FAK is not essential, at least for the initial integrin-matrix contact. Interestingly, the treatment of mice before and after inoculation significantly suppressed cell attachment to the peritoneum. Furthermore, oral administration of TAE226 greatly reduced the size of disseminated tumors and prolonged survival in tumor-bearing mice. Taken

  1. Network influences on dissemination of evidence-based guidelines in state tobacco control programs.

    PubMed

    Luke, Douglas A; Wald, Lana M; Carothers, Bobbi J; Bach, Laura E; Harris, Jenine K

    2013-10-01

    Little is known regarding the social network relationships that influence dissemination of evidence-based public health practices and policies. In public health, it is critical that evidence-based guidelines, such as the Centers for Disease Control and Prevention's Best Practices for Comprehensive Tobacco Control Programs, are effectively and efficiently disseminated to intended stakeholders. To determine the organizational and network predictors of dissemination among state tobacco control programs, interviews with members of tobacco control networks across eight states were conducted between August 2009 and September 2010. Measures included partner attributes (e.g., agency type) and relationships among network members (frequency of contact, extent of collaboration, and dissemination of Best Practices). Exponential random graph modeling was used to examine attribute and structural predictors of collaboration and dissemination among partners in each network. Although density and centralization of dissemination ties varied across states, network analyses revealed a consistent prediction pattern across all eight states. State tobacco control dissemination networks were less dense but more centralized compared with organizational contact and collaboration networks. Tobacco control partners in each state were more likely to disseminate the Best Practices guidelines if they also had existing contact and collaboration relationships with one another. Evidence-based guidelines in public health need to be efficiently and broadly disseminated if we hope to translate science into practice. This study suggests that funders, advocacy groups, and public health agencies can take advantage of existing public health organizational relationships to support the communication and dissemination of evidence-based practices and policies.

  2. Continuous Progress Program Inservice Materials.

    ERIC Educational Resources Information Center

    Chicago Board of Education, IL.

    The Continuous Progress Program of the Board of Education for the City of Chicago focuses on the improvement of education for the individual child and the upgrading of educational practices and techniques. The philosophy of the program is based on the individualized rate of teaching and learning of the pupil. Its planning and organization is…

  3. Disseminated oligodendroglial-like leptomeningeal tumor with anaplastic progression and presumed extraneural disease: case report.

    PubMed

    Kessler, Brice A; Bookhout, Christine; Jaikumar, Sivakumar; Hipps, John; Lee, Yueh Z

    2015-01-01

    We report the neuroimaging and histopathologic findings of a 12-year-old female patient with a disseminated oligodendroglial-like leptomeningeal tumor with anaplastic progression and presumed extraneural metastatic disease. These tumors may represent distinct pathology primarily seen in pediatric patients. Neuroimaging demonstrates diffuse, progressive enhancement of the leptomeninges often with interval development of intraparenchymal lesions on follow-up. Disease is typically confined to the central nervous system, though diffuse peritoneal disease was seen in our case, possibly through metastatic seeding of the abdomen via ventriculoperitoneal shunt.

  4. Progressive disseminated histoplasmosis: a systematic review on the performance of non-culture-based diagnostic tests.

    PubMed

    Falci, Diego R; Hoffmann, Elias R; Paskulin, Diego D; Pasqualotto, Alessandro C

    The diagnosis of progressive disseminated histoplasmosis is often a challenge to clinicians, especially due to the low sensitivity and long turnaround time of the classic diagnostic methods. In recent years, studies involving a variety of non-culture-based diagnostic tests have been published in the literature. We performed a systematic review by selecting studies evaluating non-culture-based diagnostic methods for progressive disseminated histoplasmosis. We searched for articles evaluating detection of antibody, antigens, as well as DNA-based diagnostic methods. A comprehensive PUBMED, Web of Science, and Cochrane Library search was performed between the years 1956 and 2016. Case reports, review articles, non-human models and series involving less than 10 patients were excluded. We found 278 articles and after initial review 18 articles were included: (12) involved antigen detection methods, (4) molecular methods, and (2) antibody detection methods. Here we demonstrate that the pursuit of new technologies is ultimately required for the early and accurate diagnosis of disseminated histoplasmosis. In particular, urinary antigen detection was the most accurate tool when compared with other diagnostic techniques. Copyright © 2016 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. All rights reserved.

  5. Sustainability of the Dissemination of an Occupational Sun Protection Program in a Randomized Trial

    ERIC Educational Resources Information Center

    Buller, David B.; Walkosz, Barbara J.; Andersen, Peter A.; Scott, Michael D.; Dignan, Mark B.; Cutter, Gary R.; Zhang, Xiao; Kane, Ilima L.

    2012-01-01

    Sustainability of an occupational sun safety program, Go Sun Smart (GSS), was explored in a randomized trial, testing dissemination strategies at 68 U.S. and Canadian ski areas in 2004-2007. All ski areas received GSS from the National Ski Areas Association through a Basic Dissemination Strategy (BDS) using conference presentations and free…

  6. Sustainability of the Dissemination of an Occupational Sun Protection Program in a Randomized Trial

    ERIC Educational Resources Information Center

    Buller, David B.; Walkosz, Barbara J.; Andersen, Peter A.; Scott, Michael D.; Dignan, Mark B.; Cutter, Gary R.; Zhang, Xiao; Kane, Ilima L.

    2012-01-01

    Sustainability of an occupational sun safety program, Go Sun Smart (GSS), was explored in a randomized trial, testing dissemination strategies at 68 U.S. and Canadian ski areas in 2004-2007. All ski areas received GSS from the National Ski Areas Association through a Basic Dissemination Strategy (BDS) using conference presentations and free…

  7. 45 CFR 1388.7 - Program criteria-dissemination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... must be responsive to community requests for information and must utilize a variety of networks... families, community members, State agencies and other provider and advocacy organizations, produce a... UAP products. (g) Dissemination products must reflect the cultural diversity of the community. (h...

  8. 45 CFR 1388.7 - Program criteria-dissemination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... must be responsive to community requests for information and must utilize a variety of networks... families, community members, State agencies and other provider and advocacy organizations, produce a... UAP products. (g) Dissemination products must reflect the cultural diversity of the community. (h...

  9. Canadian ERTS program progress report

    NASA Technical Reports Server (NTRS)

    Morley, L. W.; Mcquillan, A. K.

    1974-01-01

    Progress of the Canadian ERTS program is provided along with statistics on the production and role of ERTS images both from the CCRS in Ottawa and from the Prince Albert Saskatchewan satellite station. The types of products, difficulties of production and some of the main applications in Canada are discussed.

  10. Bilateral dissemination of malignant pleural mesothelioma via iatrogenic buffalo chest: a rare route of disease progression.

    PubMed

    Ikezoe, Kohei; Tanaka, Eisaku; Tanizawa, Kiminobu; Hashimoto, Seishu; Shindo, Toru; Noma, Satoshi; Kobashi, Yoichiro; Taguchi, Yoshio

    2012-09-01

    Buffalo chest refers to the pleuro-pleural communication that results in a single pleural cavity. Iatrogenic buffalo chest can occur following heart or heart-lung transplantation and other major thoracic surgeries. We present the case of malignant pleural mesothelioma in which iatrogenic buffalo chest after extended thymectomy caused bilateral pneumothoraces and contralateral dissemination of the disease. The free communication between bilateral pleural cavities had facilitated the rapid progression of tumor and the consequent bilateral malignant pleural effusions had made the management of disease much more difficult, leading to the early fatal outcome. To our knowledge, this is the first case of buffalo chest that was associated with bilateral malignant pleural effusions.

  11. The Science, and Art, of Program Dissemination: Strategies, Successes, and Challenges.

    PubMed

    McCoy, Kathleen P

    2015-01-01

    The purpose of this special issue is to provide readers with a greater awareness of the processes involved in dissemination, as well as existing supports that help disseminate and sustain evidence-based interventions. Although dissemination research is limited in most disciplines, it is particularly lacking in the social science field. Many interventions aimed to help children and adolescents are found to be efficacious every year, but program developers are often not equipped to understand how to scale up a program or sustain it after the initial funding. Consumers (e.g., service providers, who are consumers of interventions), on the other hand, often do not understand all that goes into implementing and scaling up an intervention. This special issue will: (a) introduce readers to the problem; (b) discuss some of the challenges with disseminating programs; and (c) present various existing supports that can help scale up and sustain interventions.

  12. E-cadherin: A determinant molecule associated with ovarian cancer progression, dissemination and aggressiveness.

    PubMed

    Rosso, Marina; Majem, Blanca; Devis, Laura; Lapyckyj, Lara; Besso, María José; Llauradó, Marta; Abascal, María Florencia; Matos, María Laura; Lanau, Lucia; Castellví, Josep; Sánchez, José Luis; Pérez Benavente, Asunción; Gil-Moreno, Antonio; Reventós, Jaume; Santamaria Margalef, Anna; Rigau, Marina; Vazquez-Levin, Mónica Hebe

    2017-01-01

    Ovarian cancer (OC) is the fifth cancer death cause in women worldwide. The malignant nature of this disease stems from its unique dissemination pattern. Epithelial-to-mesenchymal transition (EMT) has been reported in OC and downregulation of Epithelial cadherin (E-cadherin) is a hallmark of this process. However, findings on the relationship between E-cadherin levels and OC progression, dissemination and aggressiveness are controversial. In this study, the evaluation of E-cadherin expression in an OC tissue microarray revealed its prognostic value to discriminate between advanced- and early-stage tumors, as well as serous tumors from other histologies. Moreover, E-cadherin, Neural cadherin (N-cadherin), cytokeratins and vimentin expression was assessed in TOV-112, SKOV-3, OAW-42 and OV-90 OC cell lines grown in monolayers and under anchorage-independent conditions to mimic ovarian tumor cell dissemination, and results were associated with cell aggressiveness. According to these EMT-related markers, cell lines were classified as mesenchymal (M; TOV-112), intermediate mesenchymal (IM; SKOV-3), intermediate epithelial (IE; OAW-42) and epithelial (E; OV-90). M- and IM-cells depicted the highest migration capacity when grown in monolayers, and aggregates derived from M- and IM-cell lines showed lower cell death, higher adhesion to extracellular matrices and higher invasion capacity than E- and IE-aggregates. The analysis of E-cadherin, N-cadherin, cytokeratin 19 and vimentin mRNA levels in 20 advanced-stage high-grade serous human OC ascites showed an IM phenotype in all cases, characterized by higher proportions of N- to E-cadherin and vimentin to cytokeratin 19. In particular, higher E-cadherin mRNA levels were associated with cancer antigen 125 levels more than 500 U/mL and platinum-free intervals less than 6 months. Altogether, E-cadherin expression levels were found relevant for the assessment of OC progression and aggressiveness.

  13. An Educational Program of Engineering Ethics and Its Dissemination Activity

    NASA Astrophysics Data System (ADS)

    Muramatsu, Ryujiro; Nagashima, Shigeo

    Education on ethics for corporate employees, especially for engineers, seems to become increasingly important for most of companies in Japan, because some affairs or scandals caused by ethical problem in many companies were likely to subject them to operational disadvantages. Even in Hitachi, Ltd., we have worked on education of engineering ethics for two years. In this paper, we describe some activities of committees on engineering ethics, an e-learning training course which is usable on our intranet e-learning system, and a short-term in-house training course operated regularly in our training institute. And we also refer to its dissemination activities to employees in each division and some subsidiaries.

  14. National Training and Dissemination Program: LRE Public Relations Manual.

    ERIC Educational Resources Information Center

    Alvez, Aggie

    In order to champion law-related education, this volume argues that administrators of law-related education (LRE) programs should make public relations an integral part of program planning. An introductory section defines public relations and offers basic advice for developing goals and strategies. The guide advises program directors to train…

  15. Use of an Empirically Based Marriage Education Program by Religious Organizations: Results of a Dissemination Trial

    ERIC Educational Resources Information Center

    Markman, Howard J.; Whitton, Sarah W.; Kline, Galena H.; Stanley, Scott M.; Thompson, Huette; St. Peters, Michelle; Leber, Douglas B.; Olmos-Gallo, P. Antonio; Prado, Lydia; Williams, Tamara; Gilbert, Katy; Tonelli, Laurie; Bobulinski, Michelle; Cordova, Allen

    2004-01-01

    We present an evaluation of the extent to which an empirically based couples' intervention program was successfully disseminated in the community. Clergy and lay leaders from 27 religious organizations who were trained to deliver the Prevention and Relationship Enhancement Program (PREP) were contacted approximately yearly for 5 years following…

  16. Experience of Varied Presentation of Chronic Progressive Disseminated Histoplasmosis in Immunocompetent Patients: A Diagnostic Conundrum

    PubMed Central

    Ghosh, Roumi; Mishra, Pranshu; Sen, Sumit; Maiti, Prasanta Kumar; Chatterjee, Govinda

    2016-01-01

    We report two cases of chronic progressive disseminated histoplasmosis with unusual and rare clinical picture in a patient with no underlying risk factor. One 50-year-old male, presented with hoarseness of voice, chronic cough, with a history of nonresponding anti-tubercular therapy, revealed mucocutaneous lesions on examination. Fungating vocal cord lesions were visualized on bronchoscopy, raised suspicion of carcinoma. The second case, a 22-year-old female, referred to hospital with suspected vasculitis, with complaints of “off and on” fever with decreased oral intake, arthralgia, who later developed generalized nodular skin eruptions. On investigation, human immunodeficiency virus test was found to be negative in both the cases. Histopathological findings of skin biopsy, adrenal and bone marrow aspirates raised suspicion, whereas fungal cultures confirmed Histoplasma infection. Although diagnosis was delayed, but both of them were successfully treated with amphotericin B. PMID:27688460

  17. Acute disseminated encephalomyelitis progressing to multiple sclerosis: are infectious triggers involved?

    PubMed

    Smyk, Daniel S; Alexander, Anaïs K; Walker, Mary; Walker, Martin

    2014-10-01

    Acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS) are demyelinating disorders affecting the central nervous system. An autoimmune aetiology has been proposed for both. ADEM principally affects adolescents following acute infection by a variety of pathogens and has also been reported to occur following vaccination. ADEM typically resolves following medical treatment, whereas MS follows a more relapsing and remitting course. The pathogenesis of MS remains unclear, but it is thought that a combination of infectious and non-infectious environmental factors and host genetics act synergistically to cause disease. A variety of viruses, including Epstein Barr virus, cytomegalovirus, herpes simplex virus and varicella zoster virus, have been implicated as possible infectious triggers. The similar clinical and pathological presentation of ADEM and MS presents a diagnostic challenge for distinguishing ADEM from a first episode of MS. Some cases of ADEM progress to MS for reasons that are not currently clear. This review examines the evidence for infectious agents as triggers for ADEM progressing to MS and suggests potential methods that may facilitate identification of infectious agents that may be responsible for the pathogenesis of ADEM to MS.

  18. Disseminating a sun safety program to zoological parks: the effects of tailoring.

    PubMed

    Lewis, Elizabeth; Mayer, Joni A; Slymen, Donald; Belch, George; Engelberg, Moshe; Walker, Kristina; Kwon, Harry; Elder, John

    2005-09-01

    Previous research found that a sun safety program for visitors at 1 zoo increased sun safety behaviors. This randomized study compared the effects of tailored dissemination materials plus 2 brief follow-up phone calls (tailored group) versus generic materials (basic group) on implementation by other zoos of the previously evaluated sun safety program. Education directors of 126 zoos completed surveys several months following initial dissemination and 1 year later. During Summer 1, 40% of tailored group zoos and 24% of basic group zoos offered visitors at least 1 sun safety activity (odds ratio=2.2, 95% confidence interval=1.0-4.8). During Summer 2, these rates were 34% and 44%, respectively (ns). The pattern of findings suggests that tailoring had no incremental long-term impact and that the generic materials produced a good level of dissemination. (c) 2005 APA, all rights reserved

  19. Network Influences on Dissemination of Evidence-Based Guidelines in State Tobacco Control Programs

    ERIC Educational Resources Information Center

    Luke, Douglas A.; Wald, Lana M.; Carothers, Bobbi J.; Bach, Laura E.; Harris, Jenine K.

    2013-01-01

    Little is known regarding the social network relationships that influence dissemination of evidence-based public health practices and policies. In public health, it is critical that evidence-based guidelines, such as the Centers for Disease Control and Prevention's "Best Practices for Comprehensive Tobacco Control Programs," are…

  20. Beyond the Stucco Tower: Design, Development, and Dissemination of the SPARK Physical Education Programs

    ERIC Educational Resources Information Center

    McKenzie, Thomas L.; Sallis, James F.; Rosengard, Paul

    2009-01-01

    School physical education plays an important role in public health. Nonetheless, there are few evidence-based, health-related, physical education programs and very little is known about how to disseminate them for widespread use. This article (a) presents background information and a review of the completed research on the SPARK (Sports, Play, and…

  1. An Assessment System for Competence Based Education: The Educational Development, Dissemination, and Evaluation Training Program.

    ERIC Educational Resources Information Center

    Hood, Paul D.; Blackwell, Laird

    This manual provides a description of the development and a guide to the use of the assessment resources developed in connection with the Far West Development, Dissemination, and Evaluation (DD&E) Functional Competence Training Program. The document concentrates on a user-oriented description of the content, validation, and use of the final…

  2. Evaluation of the Selective Dissemination of Information (SDI) Program for the Aerospace Materials Information Center.

    ERIC Educational Resources Information Center

    Scheffler, F. L.; March, J. F.

    The Aerospace Materials Information Center (AMIC) Selective Dissemination of Information (SDI) program was evaluated by an interview technique after one year of operation. The data base for the SDI consists of the periodic document index records input to the AMIC system. The users are 63 engineers, scientists, and technical administrators at the…

  3. 29 CFR 90.22 - Dissemination of program knowledge and assistance to workers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Dissemination of program knowledge and assistance to workers. 90.22 Section 90.22 Labor Office of the Secretary of Labor CERTIFICATION OF ELIGIBILITY TO APPLY... knowledge and assistance to workers. Whenever the Commission makes an affirmative finding under section 201...

  4. 29 CFR 90.22 - Dissemination of program knowledge and assistance to workers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Dissemination of program knowledge and assistance to workers. 90.22 Section 90.22 Labor Office of the Secretary of Labor CERTIFICATION OF ELIGIBILITY TO APPLY... knowledge and assistance to workers. Whenever the Commission makes an affirmative finding under section 201...

  5. 29 CFR 90.22 - Dissemination of program knowledge and assistance to workers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Dissemination of program knowledge and assistance to workers. 90.22 Section 90.22 Labor Office of the Secretary of Labor CERTIFICATION OF ELIGIBILITY TO APPLY... knowledge and assistance to workers. Whenever the Commission makes an affirmative finding under section 201...

  6. National Evaluation of the IDEA Technical Assistance & Dissemination Program. NCEE 2014-4000

    ERIC Educational Resources Information Center

    Daley,Tamara C.; Fiore, Thomas A.; Bollmer, Julie; Nimkoff, Tamara; Lysy, Chris

    2013-01-01

    Under the Individuals with Disabilities Education Act (IDEA), the Technical Assistance and Dissemination (TA&D) Program is the U.S. Department of Education's (ED) primary vehicle for providing technical assistance (TA) to individuals and organizations responsible for serving children with disabilities and their families. The evaluation is part…

  7. Evaluation of the Dissemination Program from an Education Research and Development Center.

    ERIC Educational Resources Information Center

    Dietel, Ronald James

    This evaluation of the information dissemination program of the National Center for Research on Evaluation, Standards, and Student Testing (CRESST) uses a inclusive approach to gather, analyze, and report information to help decision makers. Results of three questionnaires, reviews and analyses of CRESST products, and Internet records were used to…

  8. Network Influences on Dissemination of Evidence-Based Guidelines in State Tobacco Control Programs

    ERIC Educational Resources Information Center

    Luke, Douglas A.; Wald, Lana M.; Carothers, Bobbi J.; Bach, Laura E.; Harris, Jenine K.

    2013-01-01

    Little is known regarding the social network relationships that influence dissemination of evidence-based public health practices and policies. In public health, it is critical that evidence-based guidelines, such as the Centers for Disease Control and Prevention's "Best Practices for Comprehensive Tobacco Control Programs," are…

  9. Disseminated tuberculosis after pregnancy progressed to paradoxical response to the treatment: report of two cases.

    PubMed

    Shinohara, Tsutomu; Kagawa, Kozo; Okano, Yoshio; Sawada, Toru; Kobayashi, Tooru; Takikawa, Masaya; Iwahara, Yoshihito; Ogushi, Fumitaka

    2016-06-13

    Early postpartum women are more likely to develop tuberculosis than nonpregnant women mainly due to immune reconstitution after delivery. Paradoxical response (PR) during antituberculosis treatment also arises via recovery from immunosuppression. However, no study focused on PR during antituberculosis treatment in a postpartum patient has been reported. We present two sequential cases (Patient 1: 26-year-old; Patient 2: 29-year-old) of postpartum tuberculosis with pulmonary and extrapulmonary lesions (Patient 1: peritonitis; Patient 2: psoas abscess secondary to spondylitis). Both cases progressed to PR (worsening of pre-existing lung infiltrations (Patients 1, 2) and new contralateral effusion (Patient 2)) in a relatively short time after initiation of treatment (Patient 1: 1 week; Patient 2: 3 weeks), suggesting that immune modulations during pregnancy and delivery may contribute to the pathogenesis of both disseminated tuberculosis and its PR. The pulmonary lesions and effusion of both cases gradually improved without change of chemotherapy regimen. Physicians should recognize PR in tuberculosis patients with postpartum and then evaluate treatment efficacy.

  10. Randomized Trial of Two Dissemination Strategies for a Skin Cancer Prevention Program in Aquatic Settings

    PubMed Central

    Escoffery, Cam; Elliott, Tom; Nehl, Eric J.

    2015-01-01

    Objectives. We compared 2 strategies for disseminating an evidence-based skin cancer prevention program. Methods. We evaluated the effects of 2 strategies (basic vs enhanced) for dissemination of the Pool Cool skin cancer prevention program in outdoor swimming pools on (1) program implementation, maintenance, and sustainability and (2) improvements in organizational and environmental supports for sun protection. The trial used a cluster-randomized design with pools as the unit of intervention and outcome. The enhanced group received extra incentives, reinforcement, feedback, and skill-building guidance. Surveys were collected in successive years (2003–2006) from managers of 435 pools in 33 metropolitan areas across the United States participating in the Pool Cool Diffusion Trial. Results. Both treatment groups improved their implementation of the program, but pools in the enhanced condition had significantly greater overall maintenance of the program over 3 summers of participation. Furthermore, pools in the enhanced condition established and maintained significantly greater sun-safety policies and supportive environments over time. Conclusions. This study found that more intensive, theory-driven dissemination strategies can significantly enhance program implementation and maintenance of health-promoting environmental and policy changes. Future research is warranted through longitudinal follow-up to examine sustainability. PMID:25521872

  11. Adopting an Evidence-Based Lifestyle Physical Activity Program: Dissemination Study Design and Methods.

    PubMed

    Dunn, Andrea L; Buller, David B; Dearing, James W; Cutter, Gary; Guerra, Michele; Wilcox, Sara; Bettinghaus, Erwin P

    2012-06-01

    BACKGROUND: There is a scarcity of research studies that have examined academic-commercial partnerships to disseminate evidence-based physical activity programs. Understanding this approach to dissemination is essential because academic-commercial partnerships are increasingly common. Private companies have used dissemination channels and strategies to a degree that academicians have not, and declining resources require academicians to explore these partnerships. PURPOSE: This paper describes a retrospective case-control study design including the methods, demographics, organizational decision-making, implementation rates, and marketing strategy for Active Living Every Day (ALED), an evidence-based lifestyle physical activity program that has been commercially available since 2001. Evidence-based public health promotion programs rely on organizations and targeted sectors to disseminate these programs although relatively little is known about organizational-level and sector-level influences that lead to their adoption and implementation. METHODS: Cases (n=154) were eligible if they had signed an ALED license agreement with Human Kinetics (HK), publisher of the program's textbooks and facilitator manuals, between 2001 and 2008. Two types of controls were matched (2:2:1) and stratified by sector and region. Active controls (Control 1; n=319) were organizations that contacted HK to consider adopting ALED. Passive controls (Control 2; n=328) were organizations that received unsolicited marketing materials and did not initiate contact with HK. We used Diffusion of Innovations Theory (DIT) constructs as the basis for developing the survey of cases and controls. RESULTS: Using the multi-method strategy recommended by Dillman, a total of n=801 cases and controls were surveyed. Most organizations were from the fitness sector followed by medical, nongovernmental, governmental, educational, worksite and other sectors with significantly higher response rates from government

  12. Programs for the Prevention of Youth Depression: Evaluation of Efficacy, Effectiveness, and Readiness for Dissemination

    PubMed Central

    Brunwasser, Steven M.; Garber, Judy

    2015-01-01

    Objective To evaluate the current state of evidence of the effectiveness of depression prevention programs for youth, assess the degree to which current evidence supports broad implementation, and outline additional steps needed to close the gap between effectiveness and dissemination. Method We used the Society for Prevention Research’s Standards of Evidence (Flay et al., 2005) to evaluate the degree to which existing depression prevention programs have established intervention efficacy, effectiveness, and readiness for dissemination. We reviewed all depression prevention programs for youth that have been evaluated in at least two published, randomized controlled trials in which the intervention was compared to a no-intervention control group. A total of 37 studies evaluating 11 different programs were reviewed with regard to depressive symptoms and diagnoses post intervention and at follow-up (at least 6 months). Results Eight programs demonstrated significant main effects on depressive symptoms relative to controls in multiple RCTs; five programs had at least one trial with significant main effects present at least one year post-intervention. Two programs demonstrated efficacy for both depressive symptoms and depressive episodes across multiple independent trials. Regarding effectiveness, six programs had at least one study showing significant effects when delivered by endogenous service providers; four programs had significant effects in studies conducted independently of the program developers. Conclusions Several programs have demonstrated promise in terms of efficacy, but no depression prevention program for children or adolescents as yet has garnered sufficient evidence of effectiveness under real-world conditions to warrant widespread dissemination at this time. PMID:25933173

  13. Programs for the Prevention of Youth Depression: Evaluation of Efficacy, Effectiveness, and Readiness for Dissemination.

    PubMed

    Brunwasser, Steven M; Garber, Judy

    2016-01-01

    The objective of this study was to evaluate the current state of evidence of the effectiveness of depression prevention programs for youth, assess the degree to which current evidence supports broad implementation, and outline additional steps needed to close the gap between effectiveness and dissemination. We used the Society for Prevention Research's Standards of Evidence (Flay et al., 2005 ) to evaluate the degree to which existing depression prevention programs have established intervention efficacy, effectiveness, and readiness for dissemination. We reviewed all depression prevention programs for youth that have been evaluated in at least two published, randomized controlled trials in which the intervention was compared to a no-intervention control group. A total of 37 studies evaluating 11 different programs were reviewed with regard to depressive symptoms and diagnoses at postintervention and follow-up (at least 6 months). Eight programs demonstrated significant main effects on depressive symptoms relative to controls in multiple randomized controlled trials; 5 programs had at least 1 trial with significant main effects present at least 1 year postintervention. Two programs demonstrated efficacy for both depressive symptoms and depressive episodes across multiple independent trials. Regarding effectiveness, 6 programs had at least 1 study showing significant effects when delivered by endogenous service providers; 4 programs had significant effects in studies conducted independently of the program developers. Several programs have demonstrated promise in terms of efficacy, but no depression prevention program for children or adolescents as yet has garnered sufficient evidence of effectiveness under real-world conditions to warrant widespread dissemination at this time.

  14. Solar lease grant program. Technical progress report

    SciTech Connect

    Not Available

    1981-04-01

    Progress on a lease program for the installation of a solar water heater with no installation charge is reported. Information on the announcement of the program, the selection of participants, the contractural agreement, progress on installation of equipment, monitoring, and evaluation is summarized. The status of the budget concerned with the program is announced. Forms used for applications for the program and an announcement from Resource Alternatives for Cilco customers are presented.

  15. Sustainability of the dissemination of an occupational sun protection program in a randomized trial.

    PubMed

    Buller, David B; Walkosz, Barbara J; Andersen, Peter A; Scott, Michael D; Dignan, Mark B; Cutter, Gary R; Zhang, Xiao; Kane, Ilima L

    2012-08-01

    Sustainability of an occupational sun safety program, Go Sun Smart (GSS), was explored in a randomized trial, testing dissemination strategies at 68 U.S. and Canadian ski areas in 2004-2007. All ski areas received GSS from the National Ski Areas Association through a Basic Dissemination Strategy (BDS) using conference presentations and free materials. Half of the ski areas were randomly assigned to a theory-based Enhanced Dissemination Strategy (EDS) with personal contact supporting GSS use. GSS use was assessed at immediate and long-term follow-up posttests by on-site observation. Use of GSS declined from immediate (M = 6.24) to long-term follow-up (M = 4.72), F(1, 62) = 6.95, p = .01, but EDS ski areas (M = 6.53) continued to use GSS more than BDS ski areas (M = 4.49), F(1, 62) = 5.75, p = .02, regardless of timing of posttest, strategy × observation F(1, 60) = 0.05, p = .83. Despite declines over time, a group of ski areas had sustained high program use and active dissemination methods had sustained positive effects on implementation.

  16. Implementation and dissemination of the Sikh American Families Oral Health Promotion Program.

    PubMed

    Northridge, Mary E; Kavathe, Rucha; Zanowiak, Jennifer; Wyatt, Laura; Singh, Hardayal; Islam, Nadia

    2017-01-31

    The Sikh American Families Oral Health Promotion Program used a community-based participatory approach to develop, implement, evaluate, and disseminate a culturally tailored oral health/healthy living curriculum for the Sikh-South Asian community. Here, we examine the impact of community engagement throughout the process of program implementation in five Gurdwaras (places of worship) in New York and New Jersey and dissemination of the findings through targeted venues and the curriculum via e-Health resources. An interactive curriculum was developed (consisting of four core and three special topics) based upon a community-led needs assessment, adaptation of evidence-based oral health curricula, guidance from professional dental and medical associations, and input from Community Advisory Board (CAB) members. The Consolidated Framework for Implementation Research guided a mixed-method evaluation, consisting of both process and outcome measures. Five trained community educators delivered a total of 42 educational sessions. Improved oral hygiene behaviors and self-efficacy were found among program participants. For participants with no dental insurance prior to program enrollment (n = 58), 81.0% credited the program with helping them obtain insurance for themselves or their children. Further, for participants with no dentist prior to program enrollment (n = 68), 92.6% credited the program with helping them or their children find a local dentist. Short videos in Punjabi were created in response to feedback received from community educators and CAB members to reach men, especially. Community engagement was key to successful program implementation and dissemination, from the implementation leaders (community educators) to the opinion leaders and champions (CAB members).

  17. Tumor-associated macrophages of the M2 phenotype contribute to progression in gastric cancer with peritoneal dissemination.

    PubMed

    Yamaguchi, Takahisa; Fushida, Sachio; Yamamoto, Yasuhiko; Tsukada, Tomoya; Kinoshita, Jun; Oyama, Katsunobu; Miyashita, Tomoharu; Tajima, Hidehiro; Ninomiya, Itasu; Munesue, Seiichi; Harashima, Ai; Harada, Shinichi; Yamamoto, Hiroshi; Ohta, Tetsuo

    2016-10-01

    Tumor-associated macrophages (TAMs) of the M2 phenotype are known to promote tumor proliferation and to be associated with a poor prognosis in numerous cancers. Here, we investigated whether M2 macrophages participate in the development of peritoneal dissemination in gastric cancer. The characteristics of peritoneal macrophages in gastric cancer patients with or without peritoneal dissemination were examined by flow cytometry and the real-time quantitative polymerase chain reaction. The effects of M2 macrophages on phenotypic changes of the gastric cancer cell line MKN45 were assessed with a direct or indirect co-culture system in vitro and an in vivo mouse xenograft model. The number of peritoneal macrophages with the M2 phenotype (CD68(+)CD163(+) or CD68(+)CD204(+)) was significantly higher in gastric cancer patients with peritoneal dissemination than in those without peritoneal dissemination. Higher expression of the M2-related messenger RNAs (IL-10, vascular endothelial growth factor A, vascular endothelial growth factor C, matrix metalloproteinase 1, and amphiregulin) and lower expression of M1-related messenger RNAs (TNF-α, CD80, CD86, and IL-12p40) were also confirmed in the TAMs. Macrophage co-culture with gastric cancer cells converted M1 phenotype into M2 phenotype. Moreover, the coexistence of MKN45 cells with M2 macrophages resulted in cancer cell proliferation and an acceleration of tumor growth in the xenograft model. Intraperitoneal TAMs in gastric cancer patients with peritoneal dissemination were polarized to the M2 phenotype, and could contribute to tumor proliferation and progression. Therefore, intraperitoneal TAMs are expected to be a promising target in the treatment of peritoneal dissemination in gastric cancer.

  18. A Program and Its Implications for Dissemination and School Improvement Policy. Linking R&D with Schools.

    ERIC Educational Resources Information Center

    Louis, Karen Seashore; Rosenblum, Sheila

    A study of the National Institute of Education's Research and Development Utilization (RDU) program illuminates several policy choices for federal and state support of dissemination and school improvement projects. RDU was established in 1976 to disseminate educational materials and thereby help schools clarify and solve local problems. Seven…

  19. State Prekindergarten Program. Progress Report, Winter 1989.

    ERIC Educational Resources Information Center

    Hitz, Randy; Driscoll, Amy

    Progress of Oregon's State Prekindergarten Program (SPP) during its first 3 months of program operation is reported. Serving mostly low-income, 3- and 4-year-old children, the SPP offers health, nutrition, education, and social services to children and their families. Parent involvement and education are important program components. This progress…

  20. Technology Programs That Work. A National Diffusion Network Resource of Exemplary Programs Approved by the Joint Dissemination Review Panel, Department of Education.

    ERIC Educational Resources Information Center

    Vaughan, Larry, Ed.

    This report presents brief descriptions of exemplary programs validated by the National Diffusion Network (NDN) and approved for national dissemination by the Joint Dissemination Review Panel, which focus specifically on the effective use of technology in education. As exemplary projects called Developer Demonstrators, 12 of the programs described…

  1. Progress of the RERTR program in 1999.

    SciTech Connect

    Travelli, A.

    1999-09-29

    This paper describes the progress achieved by the Reduced Enrichment for Research and Test Reactors (RERTR) Program in collaboration with its many international partners during 1999 and discusses planned activities for the coming year.

  2. Progress Evaluation of the National Estuary Program

    EPA Pesticide Factsheets

    A guidance to help the U.S. EPA determine whether the 28 programs included in NEP are making adequate progress implementing their CCMP and therefore merit continued funding under §320 of the Clean Water Act.

  3. Typical Facial Lesions: A Window of Suspicion for Progressive Disseminated Histoplasmosis—A Case of Asian Prototype

    PubMed Central

    Panda, Prasan K.; Jain, Siddharth; Sood, Rita; Yadav, Rajni

    2016-01-01

    Histoplasmosis is caused by a dimorphic fungus Histoplasma capsulatum in endemic areas, mainly America, Africa, and Asia. In India, it is being reported from most states; however, it is endemic along the Ganges belt. We report a case of an apparently immunocompetent male who presented with 3-month history of fever, cough, and weight loss with recent onset odynophagia and had hepatosplenomegaly and mucocutaneous lesions over the face. The differential diagnosis of leishmaniasis, tuberculosis, leprosy, fungal infection, lymphoproliferative malignancy, and other granulomatous disorders was considered, but he succumbed to his illness. Antemortem skin biopsy and bone marrow aspiration along with postmortem liver, lung, and spleen biopsy showed disseminated histoplasmosis. This case highlights the need for an early suspicion of progressive disseminated histoplasmosis in the presence of classical mucocutaneous lesions even in an immunocompetent patient suffering from a febrile illness. Cure rate approaches almost 100% with early treatment, whereas it is universally fatal if left untreated. PMID:27752372

  4. 2010 Annual Progress Report: DOE Hydrogen Program

    SciTech Connect

    Not Available

    2011-02-01

    In the past year, the DOE Hydrogen Program (the Program) made substantial progress toward its goals and objectives. The Program has conducted comprehensive and focused efforts to enable the widespread commercialization of hydrogen and fuel cell technologies in diverse sectors of the economy. With emphasis on applications that will effectively strengthen our nation's energy security and improve our stewardship of the environment, the Program engages in research, development, and demonstration of critical improvements in the technologies. Highlights of the Program's accomplishments can be found in the sub-program chapters of this report.

  5. Dissemination and benefits of a replicable Tai Chi and Qigong program for older adults.

    PubMed

    Jahnke, Roger A; Larkey, Linda K; Rogers, Carol

    2010-01-01

    Tai Chi and Qigong (TCQG) show promise for improving many health outcomes and are recommended for dissemination to older adults. A simplified, easy-to-replicate version of TCQG, "Tai Chi Easy," was tested using a train-the-trainer method to demonstrate feasibility of dissemination to a widespread population of older adults through community sites and achievement of perceived outcomes. Nonexpert facilitators known as "practice leaders" were trained to implement Tai Chi Easy sessions at 18 sites across the United States. Outstanding facilitator (100%) and participant (94%) adherence was achieved. With 330 completers, mean age 73 years, significant improvements were found for participants' perceived stress levels (P = .003). Sleep quality and energy/vitality were markedly improved. Eighty-nine percent enjoyed the program, 91% were committed to continue, and 67% stated that they had increased their weekly levels of physical activity. A train-the-facilitator model for Tai Chi Easy is easily disseminated to older adults and may promote a sustainable alternative exercise, yielding favorable quality of life benefits. Copyright 2010 Mosby, Inc. All rights reserved.

  6. Evaluating Youth Development Programs: Progress and Promise

    ERIC Educational Resources Information Center

    Roth, Jodie L.; Brooks-Gunn, Jeanne

    2016-01-01

    Advances in theories of adolescent development and positive youth development have greatly increased our understanding of how programs and practices with adolescents can impede or enhance their development. In this article the authors reflect on the progress in research on youth development programs in the last two decades, since possibly the…

  7. Status and progress of the RERTR Program

    SciTech Connect

    Travelli, A.

    1993-12-31

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. The major events, findings, and activities of 1993 are reviewed after a brief summary of the results which the RERTR Program had achieved by the end of 1992 in collaboration with its many international partners.

  8. Evaluating Youth Development Programs: Progress and Promise

    ERIC Educational Resources Information Center

    Roth, Jodie L.; Brooks-Gunn, Jeanne

    2016-01-01

    Advances in theories of adolescent development and positive youth development have greatly increased our understanding of how programs and practices with adolescents can impede or enhance their development. In this article the authors reflect on the progress in research on youth development programs in the last two decades, since possibly the…

  9. Free acquisition and dissemination of data through remote sensing. [Landsat program legal aspects

    NASA Technical Reports Server (NTRS)

    Hosenball, S. N.

    1976-01-01

    Free acquisition and dissemination of data through remote sensing is discussed with reference to the Landsat program. The role of the Scientific and Technical Subcommittee of the U.N. General Assembly's Committee on the Peaceful Uses of Outer Space has made recommendations on the expansion of existing ground stations and on the establishment of an experimental center for training in remote sensing. The working group for the legal subcommittee of the same U.N. committee indicates that there are common elements in the three drafts on remote sensing submitted to it: a call for international cooperation and the belief that remote sensing should be conducted for the benefit of all mankind.

  10. Consumer engagement and the development, evaluation and dissemination of evidence-based parenting programs

    PubMed Central

    Sanders, Matthew R.; Kirby, James N.

    2013-01-01

    A consumer perspective can contribute much to enhancing the “ecological fit” of population level parenting interventions so they meet the needs of parents. This approach involves building relationships with consumer groups and soliciting consumer input into the relevance and acceptability of interventions, clarifying the enablers and barriers to engagement and involvement of parents, and clarifying variables that influence a parent’s program completion. The adoption of a more collaborative approach to working with consumers is important if meaningful population level change in the prevalence of serious social, emotional and behavioral problems in children and young people is to be achieved. Parents seeking assistance for their children’s behavior come from a diverse range of socioeconomic backgrounds, educational levels, cultures and languages. This paper examines consumer engagement strategies that can be employed throughout the process of program development, evaluation, training and dissemination and in “scaling up” the intervention. We argue that a multi-level public health approach to parenting intervention requires a strong consumer perspective to enable interventions to be more responsive to the preferences and needs of families and to ensure improved population reach of interventions. Examples from large scale dissemination trials are used to illustrate how consumer input can result in an increasingly differentiated suite of evidence-based parenting programs. PMID:22440062

  11. Consumer engagement and the development, evaluation, and dissemination of evidence-based parenting programs.

    PubMed

    Sanders, Matthew R; Kirby, James N

    2012-06-01

    A consumer perspective can contribute much to enhancing the "ecological fit" of population-level parenting interventions so they meet the needs of parents. This approach involves building relationships with consumer groups and soliciting consumer input into the relevance and acceptability of interventions, clarifying the enablers and barriers to engagement and involvement of parents, and clarifying variables that influence a parent's program completion. The adoption of a more collaborative approach to working with consumers is important if meaningful population-level change in the prevalence of serious social, emotional, and behavioral problems in children and young people is to be achieved. Parents seeking assistance for their children's behavior come from a diverse range of socioeconomic backgrounds, educational levels, cultures, and languages. This paper examines consumer engagement strategies that can be employed throughout the process of program development, evaluation, training, and dissemination, and in "scaling up" the intervention. We argue that a multilevel public health approach to parenting intervention requires a strong consumer perspective to enable interventions to be more responsive to the preferences and needs of families and to ensure improved population reach of interventions. Examples from large-scale dissemination trials are used to illustrate how consumer input can result in an increasingly differentiated suite of evidence-based parenting programs.

  12. ESEA, Title III Dissemination Program Evaluation Report, 1972-73, 1973-74. Sections I and II.

    ERIC Educational Resources Information Center

    Soper, Dorothy B.

    This report evaluates the New Jersey ESEA Title III dissemination program during its first two years, 1972-74. Purposes of the program are to (a) determine if essential elements of successful education programs can be transferred from originating districts to adopter districts while yielding comparable student gains, and (b) provide educators with…

  13. Progress in cartography, EROS program

    NASA Technical Reports Server (NTRS)

    Colvocoresses, A. P.; Mcewen, R. B.

    1973-01-01

    During the past 7 years the Interior Department EROS (Earth Resources Observation Systems) program with NASA sponsorship has conducted cartographic research based on high altitude aerial and space photographs. The research has centered on the direct use of the image and its transformation into so-called photo or image maps. Today the cartographers of the Geological Survey have a real opportunity for making maps from data supplied by ERTS-1 which is dedicated to remote sensing of the earth.

  14. Disseminating ASD interventions: a pilot study of a distance learning program for parents and professionals.

    PubMed

    Wainer, Allison L; Ingersoll, Brooke R

    2013-01-01

    There is a need for the adaptation of training in evidence-based interventions to non-traditional methods, particularly for individuals working with children with autism spectrum disorders (ASD). An internet-based self-directed distance learning program was created to teach reciprocal imitation training, a naturalistic behavioral intervention aimed at increasing imitation in children with ASD. A single-subject multiple-baseline design study evaluated the effect of the program on changes in therapist (sample 1) and parent (sample 2) knowledge and behavior, and changes in child behavior. Adult participants improved their knowledge and use of the intervention techniques, and child participants improved their rates of imitation. Results suggest that a self-directed distance learning program may be effective for disseminating evidence-based practices to individuals working with children with ASD.

  15. Bullying in school: evaluation and dissemination of the Olweus Bullying Prevention Program.

    PubMed

    Olweus, Dan; Limber, Susan P

    2010-01-01

    The nature and extent of bullying among school children is discussed, and recent attention to the phenomenon by researchers, the media, and policy makers is noted. The Olweus Bullying Prevention Program (OBPP) is a comprehensive, school-wide program that was designed to reduce bullying and achieve better peer relations among students in elementary, middle, and junior high school grades. Several large-scale studies from Norway are reviewed, which provide compelling evidence of the program's effectiveness in Norwegian schools. Studies that have evaluated the OBPP in diverse settings in the United States have not been uniformly consistent, but they have shown that the OBPP has had a positive impact on students' self-reported involvement in bullying and antisocial behavior. Efforts to disseminate the OBPP in Norway and the United States are discussed.

  16. Dissemination and implementation science in program evaluation: A telemental health clinical consultation case example.

    PubMed

    Arora, Prerna G; Connors, Elizabeth H; Blizzard, Angela; Coble, Kelly; Gloff, Nicole; Pruitt, David

    2017-02-01

    Increased attention has been placed on evaluating the extent to which clinical programs that support the behavioral health needs of youth have effective processes and result in improved patient outcomes. Several theoretical frameworks from dissemination and implementation (D&I) science have been put forth to guide the evaluation of behavioral health program implemented in the context of real-world settings. Although a strong rationale for the integration of D&I science in program evaluation exists, few examples exist available to guide the evaluator in integrating D&I science in the planning and execution of evaluation activities. This paper seeks to inform program evaluation efforts by outlining two D&I frameworks and describing their integration in program evaluation design. Specifically, this paper seeks to support evaluation efforts by illustrating the use of these frameworks via a case example of a telemental health consultation program in pediatric primary care designed to improve access to behavioral health care for children and adolescents in rural settings. Lessons learned from this effort, as well as recommendations regarding the future evaluation of programs using D&I science to support behavioral health care in community-based settings are discussed.

  17. National dissemination of chronic disease self-management education programs: an incremental examination of delivery characteristics.

    PubMed

    Smith, Matthew Lee; Ory, Marcia G; Ahn, SangNam; Kulinski, Kristie P; Jiang, Luohua; Horel, Scott; Lorig, Kate

    2014-01-01

    With a near 20-year developmental history as an evidence-based program, the suite of Chronic Disease Self-Management Education (CDSME) programs were selected in 2010 for grand-scale dissemination in a federally supported initiative to improve the health of older Americans. The primary charge of this national effort was to establish a sustainable program delivery system for empowering American adults with one or more chronic conditions to better manage their health. The current study focused on a series of dissemination and implementation science research questions to: (1) examine the geographic distribution of participation in this initiative across the Unites States; (2) describe workshop characteristics engaged to reach program participants in various settings; and (3) describe personal characteristics of the first 100,000 participants. Each subsequent entering cohort was descriptively examined to indicate whether there was constancy or change in delivery sites and populations reached over time. Findings show a strengthening of the workshop delivery infrastructure in that it took 9.4 months to reach the first 25,000 participants in 853 counties compared to 5.4 months to reach the last 25,000 participants in 1,109 counties. The workshop delivery characteristics and participant characteristics remained relatively consistent across increments of 25,000 participants reached, although general trends were observed for some variables. For example, after reaching the first 25,000 participants, subsequent groups of 25,000 participants were reached more quickly. Additionally, workshops were increasingly delivered in ZIP Codes with higher percentages of families residing below the federal poverty line. As more participants were reached, more participants with chronic conditions were enrolled. This national translational study illustrates the rapid expansion of CDSME programs throughout the United States and capability to reach diverse populations in a variety of

  18. Development, evaluation, and multinational dissemination of the triple P-Positive Parenting Program.

    PubMed

    Sanders, Matthew R

    2012-01-01

    The quality of parenting children receive has a major influence on their development, well-being, and life opportunities. Of all the potentially modifiable influences that can be targeted through preventive interventions, none are more important than the quality of parenting children experience. Prevention interventions targeting parenting should be widely used to promote positive developmental outcomes for children and adolescents. This review argues that the development of comprehensive evidence-based strategies to improve the quality of parenting is best viewed as a major public health challenge. Using the Triple P-Positive Parenting Program as an exemplar, the initial development, gradual transformation into a public health model, and then global dissemination of the approach is described. The assumptions underpinning the public health approach to parenting support are discussed, along with key criteria that need to be met for the approach to work. Factors that facilitate and impede the global implementation and dissemination of evidence-based parenting programs are considered along with implications for future research, policy, and practice.

  19. Sustaining evidence-based prevention programs: correlates in a large-scale dissemination initiative.

    PubMed

    Cooper, Brittany Rhoades; Bumbarger, Brian K; Moore, Julia E

    2015-01-01

    Over the past four decades, significant strides have been made in the science of preventing youth problem behaviors. Subsequently, policymakers and funders have begun to insist on the use of evidence-based programs (EBPs) as a requirement for funding. However, unless practitioners are able to sustain these programs beyond initial seed funding, they are unlikely to achieve their ultimate goal of broad public health impact. Despite its obvious importance, sustainability has received relatively little attention in prevention science until recently. Moreover, there have been few opportunities to study the correlates of sustainability in large-scale, multi-year initiatives involving multiple programs. The present study examined rates of sustainment of a wide range of proven-effective prevention and intervention programs; identified factors related to organizational support and readiness, program and implementer characteristics, and sustainability planning that distinguished sustained programs; and examined variability in these associations across classroom-based, community/mentoring, family-focused prevention, and family treatment program types within the context of a state-wide EBP dissemination initiative in Pennsylvania over 4 years. The majority of EBPs sustained functioning 2 years or more beyond their initial funding. In general, sustained programs reported greater community coalition functioning, communication to key stakeholders, knowledge of the program's logical model, communication with the trainer or program developer, and sustainability planning. In addition to these universal correlates, important program-specific correlates emerged as well. Implications for the technical assistance and support necessary to promote the sustainability of EBPs in nonresearch contexts are also discussed.

  20. Advancing the science of dissemination and implementation in behavioral medicine: evidence and progress.

    PubMed

    Chan, Carina K Y; Oldenburg, Brian; Viswanath, Kasisomayajula

    2015-06-01

    The enormous time lag between the discovery of new knowledge and its implementation poses a significant challenge to improving public health because of the very slow uptake into policy and practice. The field of dissemination and implementation research in behavioral medicine is receiving increased attention because of the keen interest in accelerating knowledge transfer from relevant research to improve the health and wellbeing of populations in many different settings, contexts, and countries around the world. This is particularly important in high-risk populations, resource-poor and developing regions of the world where the difference in health systems, languages, and cultures very significantly influences the translation of evidence into policy and practice. Moreover, demonstrating the broader societal and economic value of behavioral interventions in settings where they are implemented can further support the sustainability, uptake, and implementation of these findings in other settings and contexts. This special issue presents a series of empirical studies, reviews, and case studies that address dissemination, implementation, and translation issues in both developed and developing countries. Specifically, the learnings from the application of many and varied theories and research methodologies are very relevant for bridging the current division between research findings and their translation and uptake into policy and practice.

  1. Safe and competent opioid prescribing education: Increasing dissemination with a train-the-trainer program.

    PubMed

    Zisblatt, Lara; Hayes, Sean M; Lazure, Patrice; Hardesty, Ilana; White, Julie L; Alford, Daniel P

    2017-01-01

    Due to the high prevalence of prescription opioid misuse, the US Food and Drug Administration (FDA) mandated a Risk Evaluation and Mitigation Strategy (REMS) requiring manufacturers of extended-release/long-acting (ER/LA) opioids to fund continuing education based on an FDA curricular Blueprint. This paper describes the Safe and Competent Opioid Prescribing Education (SCOPE of Pain) train-the-trainer program and its impact on (1) disseminating the SCOPE of Pain curriculum and (2) knowledge, confidence, attitudes, and performance of the participants of trainer-led compared with expert-led meetings. SCOPE of Pain is a 3-hour ER/LA opioid REMS education. In addition to expert-led live statewide meetings, a 2-hour train-the-trainer (TTT) workshop was developed to increase dissemination nationally. The trainers were expected to conduct SCOPE of Pain meetings at their institutions. Participants of both the trainer-led and expert-led SCOPE of Pain programs were surveyed immediately post and 2 months post meetings to assess improvements in knowledge, confidence, attitudes, and self-reported safe opioid prescribing practices. During 9 months (May 2013 to February 2014), 89 trainers were trained during 9 TTT workshops in 9 states. Over 24 months (May 2013 to April 2015), 33% of the trainers conducted at least 1 SCOPE of Pain training, with a total of 79 meetings that educated 1419 participants. The average number of meetings of those who conducted at least 1 meeting was 2.8 (range: 1-19). The participants of the trainer-led programs were significantly more likely to be practicing in rural settings than those who participated in the expert-led meetings (39% vs. 26%, P < .001). At 2 months post training, there were no significant differences in improvements in participant knowledge, confidence, attitudes, and performance between expert-led and trainer-led meetings. The SCOPE of Pain TTT program holds promise as an effective dissemination strategy to increase guideline

  2. Electric and Magnetic Fields Research and Public Information Dissemination Program annual report for fiscal year 1996

    SciTech Connect

    1997-06-01

    The Electric and Magnetic Fields (EMF) Research and Public Information Dissemination (RAPID) Program was authorized by the Energy Policy Act of 1992 as a near-term effort to expand and accelerate the research needed to address the EMF issue. As required by this legislation, the EMF Interagency Committee, the National EMF Advisory Committee (NEMFAC), and the National Academy of Sciences (NAS) are providing valued input and advice for the direction of this program. With this input and advice, the Department of Energy (DOE) and the National Institute of Environmental Health Sciences (NIEHS) have developed and are implementing five-year program plans. Multi-year health effects research projects and related EMF measurement and exposure assessment projects are underway using funds appropriated in fiscal years 1994, 1995, and 1996 together with voluntary non-Federal contributions. The results of these research projects, along with the results of other EMF research, will be used as input to the hazard evaluation effort, which is the focus of the EMF RAPID Program. A coordinated interagency program is underway to communicate needed information on the EMF issue in a clear manner to the public and other decision makers.

  3. A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination

    PubMed Central

    Frittoli, Emanuela; Palamidessi, Andrea; Marighetti, Paola; Confalonieri, Stefano; Bianchi, Fabrizio; Malinverno, Chiara; Mazzarol, Giovanni; Viale, Giuseppe; Martin-Padura, Ines; Garré, Massimilliano; Parazzoli, Dario; Mattei, Valentina; Cortellino, Salvatore; Bertalot, Giovanni

    2014-01-01

    The mechanisms by which tumor cells metastasize and the role of endocytic proteins in this process are not well understood. We report that overexpression of the GTPase RAB5A, a master regulator of endocytosis, is predictive of aggressive behavior and metastatic ability in human breast cancers. RAB5A is necessary and sufficient to promote local invasion and distant dissemination of various mammary and nonmammary tumor cell lines, and this prometastatic behavior is associated with increased intratumoral cell motility. Specifically, RAB5A is necessary for the formation of invadosomes, membrane protrusions specialized in extracellular matrix (ECM) degradation. RAB5A promotes RAB4- and RABENOSYN-5–dependent endo/exocytic cycles (EECs) of critical cargos (membrane-type 1 matrix metalloprotease [MT1-MMP] and β3 integrin) required for invadosome formation in response to motogenic stimuli. This trafficking circuitry is necessary for spatially localized hepatocyte growth factor (HGF)/MET signaling that drives invasive, proteolysis-dependent chemotaxis in vitro and for conversion of ductal carcinoma in situ to invasive ductal carcinoma in vivo. Thus, RAB5A/RAB4 EECs promote tumor dissemination by controlling a proteolytic, mesenchymal invasive program. PMID:25049275

  4. Teaching the Talented Program: A Progress Report.

    ERIC Educational Resources Information Center

    Gear, Gayle Haywood

    Presented is a progress report (covering 1969-74) on the University of Connecticut's Teaching the Talented (TTT) Program, which is designed to recruit and train leadership personnel to work with gifted disadvantaged youth. Forty-six teachers and school administrators experienced in working with minority populations were recruited as TTT Fellows.…

  5. [Cancer Cells as Dynamic System - Molecular and Phenotypic Changes During Tumor Formation, Progression and Dissemination].

    PubMed

    Sommerová, L; Ondroušková, E; Hrstka, R

    Dynamic, punctual and perfectly coordinated cellular response to internal and external stimuli is a crucial prerequisite for adaptation of mammalian cells to all changes that occur during cellular development under physiological conditions. Hijacking this ability is characteristic for tumor cells that are capable to adapt to unfavorable conditions which contribute to the formation and development of cancer during the process of tumor formation and progression. By changing key mechanisms, malignant cells can avoid cell death and thus allow development and spread of the tumor. The changes at the genetic level are manifested by various phenotypic characteristics, through which tumor cells are able to escape defense mechanisms, to acquire resistance to treatment, to invade and to create secondary tumors. In recent years, one of the most studied properties include changes in energy metabolism, when tumor cells specifically control reprogramming of the main metabolic pathways for their own benefit and to satisfy their increased needs not only for energy, but also for building materials required for increased proliferation. To adapt to extracellular conditions, it is necessary that cells undergo morphological changes, where modifications in the cell shape through reorganization of cytoskeletal filaments allow tumor cells to increase their invasiveness and other aggressive features. Clarifying these changes together with understanding of the switch in the genetic program within cancer cells, which allows them to overcome different stages of differentiation from cancer stem cells to fully differentiated cells, would be an important prerequisite for identification of the cancer cell "weaknesses" and may lead to improved cancer treatment. The ability of tumor cells to alter the rules of their own organism thus represents an important challenge for oncological research.Key words: cellular reprogramming - cancer cell plasticity - cancer metabolism - tumor heterogeneity

  6. The Science, and Art, of Program Dissemination: Strategies, Successes, and Challenges

    ERIC Educational Resources Information Center

    McCoy, Kathleen P.

    2015-01-01

    The purpose of this special issue is to provide readers with a greater awareness of the processes involved in dissemination, as well as existing supports that help disseminate and sustain evidence-based interventions. Although dissemination research is limited in most disciplines, it is particularly lacking in the social science field. Many…

  7. Dissemination for School Improvement: An Analysis of Nine Federal Education Programs. A Study of Dissemination Efforts Supporting School Improvement. People, Policies, and Practices: Examining the Chain of School Improvement, Volume V.

    ERIC Educational Resources Information Center

    Shive, Glenn; Eiseman, Jeffrey W.

    In the fifth volume of a 10-volume report, the development of federal dissemination-related school improvement policy is depicted through short case studies of nine distinctly different programs sponsored by the Department of Education: Elementary Secondary Education Act (ESEA) Title III/IV-C, the Joint Dissemination Review Panel, the National…

  8. Evaluating Youth Development Programs: Progress and Promise

    PubMed Central

    Brooks-Gunn, Jeanne

    2016-01-01

    Advances in theories of adolescent development and positive youth development have greatly increased our understanding of how programs and practices with adolescents can impede or enhance their development. In this paper the authors reflect on the progress in research on youth development programs in the last two decades, since possibly the first review of empirical evaluations by Roth, Brooks-Gunn, Murray, and Foster (1998). The authors use the terms Version 1.0, 2.0 and 3.0 to refer to changes in youth development research and programs over time. They argue that advances in theory and descriptive accounts of youth development programs (Version 2.0) need to be coupled with progress in definitions of youth development programs, measurement of inputs and outputs that incorporate an understanding of programs as contexts for development, and stronger design and evaluation of programs (Version 3.0). The authors also advocate for an integration of prevention and promotion research, and for use of the term youth development rather than positive youth development. PMID:28077922

  9. Best practices: the Johnson & Johnson--Dartmouth community mental health program: disseminating evidence-based practice.

    PubMed

    Drake, Robert E; Becker, Deborah R; Goldman, Howard H; Martinez, Rick A

    2006-03-01

    This column describes a private-public-academic collaboration in six states and the District of Columbia designed to provide evidence-based supported employment for persons with psychiatric disabilities by using best practices for program implementation. Dissemination strategies included collaborative state-level administrative oversight, longitudinal training based on established fidelity criteria, outcome-based supervision, problem solving by local experts, and selection of intervention sites on the basis of their motivation to participate. The number of clients served at participating sites increased steadily over 11 quarters, and the proportion of clients competitively employed stayed consistently over 40 percent. The project successfully combined industry's emphasis on outcomes with academia's emphasis on research-based interventions to enhance public services.

  10. Progressive disseminated histoplasmosis in the HIV population in Europe in the HAART era. Case report and literature review.

    PubMed

    Martin-Iguacel, R; Kurtzhals, J; Jouvion, G; Nielsen, S D; Llibre, J M

    2014-08-01

    In highly endemic areas, up to 20 % of human immunodeficiency virus (HIV)-infected persons will develop progressive disseminated histoplasmosis (PDH). Europe is not endemic to histoplasmosis, and the disease is mainly found in immigrants often co-infected with HIV. We present a case of a patient with HIV and PDH highlighting the possible diagnostic difficulties that may arise in a non-endemic area and review the literature of histoplasmosis in the context of HIV infection with special focus on Europe. When cellular immunity wanes (usually at CD4 T-lymphocyte counts <150 cells/μL) histoplasma infection, acquired earlier, can reactivate and disseminate. PDH is an acquired immune deficiency syndrome(AIDS)-defining disease and a life-threatening infection, with a clinical spectrum ranging from an acute, fatal course with lung infiltrates and respiratory failure, shock, coagulopathy and multi-organ failure, to a more subacute disease with focal organ involvement, pancytopenia and hepatosplenomegaly. Mortality rates remain high for untreated patients, but early diagnosis, proper antifungal treatment and early initiation of antiretroviral therapy have improved the prognosis. European infectious diseases physicians, microbiologists and pathologists must be aware of histoplasmosis, particularly when facing HIV-infected immigrants from endemic areas. This is increasingly important due to migration and travel activities from these areas.

  11. Enhancing industry-based dissemination of an occupational sun protection program with theory-based strategies employing personal contact.

    PubMed

    Buller, David B; Andersen, Peter A; Walkosz, Barbara J; Scott, Michael D; Cutter, Gary R; Dignan, Mark B; Kane, Ilima L; Zhang, Xiao

    2012-01-01

    Industry-based strategies for dissemination of an evidence-based occupational sun protection program, Go Sun Smart (GSS), were tested. Two dissemination strategies were compared in a randomized trial in 2004-2007. The North American ski industry. Ski areas in the United States and Canada (n  =  69) and their senior managers (n  =  469). Employers received GSS through a basic dissemination strategy (BDS) from the industry's professional association that included conference presentations and free starter kits. Half of the areas also received the enhanced dissemination strategy (EDS), in which project staff met face-to-face with managers and made ongoing contacts to support program use. Observation of program materials in use and managers' reports on communication about sun protection. The effects of two alternative dissemination strategies were compared on program use using PROC MIXED in SAS, adjusted for covariates using one-tailed p values. Ski areas receiving the EDS used more GSS materials (x¯  =  7.36) than those receiving the BDS (x¯  =  5.17; F  =  7.82, p < .01). Managers from more areas receiving the EDS reported communicating about sun protection in employee newsletters/flyers (x¯  =  .97, p  =  .04), in guest e-mail messages (x¯  =  .75, p  =  .02), and on ski area Web sites (x¯  =  .38, p  =  .02) than those receiving the BDS (x¯  =  .84, .50, .15, respectively). Industry professional associations play an important role in disseminating prevention programs; however, active personal communication may be essential to ensure increased implementation fidelity.

  12. Enhancing Industry-based Dissemination of an Occupational Sun Protection Program with Theory-based Strategies Employing Personal Contact

    PubMed Central

    Buller, David B.; Andersen, Peter A.; Walkosz, Barbara J.; Scott, Michael D.; Cutter, Gary R.; Dignan, Mark B.; Kane, Ilima L.; Zhang, Xiao

    2012-01-01

    Purpose Industry-based strategies for dissemination of an evidence-based occupational sun protection program, Go Sun Smart (GSS), were tested. Design Two dissemination strategies were compared in a randomized trial in 2004 – 2007. Setting The North American ski industry. Subjects Ski areas in the United States and Canada (n=69) and their senior managers (n=469). Intervention Employers received GSS through a Basic Dissemination Strategy (BDS) from the industry’s professional association which included conference presentations and free starter kits. Half of the areas also received the Enhanced Dissemination Strategy (EDS), in which project staff met face-to-face with managers and made ongoing contacts to support program use. Measures Observation of program materials in use and managers’ reports on communication about sun protection. Analysis The effects of two alternative dissemination strategies were compared on program use using PROC MIXED in SAS, adjusted for covariates using 1-tailed p-values. Results Ski areas receiving the EDS used more GSS materials (M=7.36) than those receiving the BDS (M=5.17; F=7.82, p<.01). Managers from more areas receiving the EDS reported communicating about sun protection in employee newsletters/flyers (M=0.97, p=.04), in guest email messages (M=0.75, p=.02), and on ski area websites (M=0.38, p=.02) than those receiving the BDS (M=0.84, 0.50, 0.15, respectively). Conclusion Industry professional associations play an important role in disseminating prevention programs; however, active personal communication may be essential to ensure increased implementation fidelity. PMID:22747318

  13. NAADP-Dependent Ca2+ Signaling Controls Melanoma Progression, Metastatic Dissemination and Neoangiogenesis

    PubMed Central

    Favia, Annarita; Pafumi, Irene; Desideri, Marianna; Padula, Fabrizio; Montesano, Camilla; Passeri, Daniela; Nicoletti, Carmine; Orlandi, Augusto; Del Bufalo, Donatella; Sergi, Manuel; Ziparo, Elio; Palombi, Fioretta; Filippini, Antonio

    2016-01-01

    A novel transduction pathway for the powerful angiogenic factor VEGF has been recently shown in endothelial cells to operate through NAADP-controlled intracellular release of Ca2+. In the present report the possible involvement of NAADP-controlled Ca2+ signaling in tumor vascularization, growth and metastatic dissemination was investigated in a murine model of VEGF-secreting melanoma. Mice implanted with B16 melanoma cells were treated with NAADP inhibitor Ned-19 every second day for 4 weeks and tumor growth, vascularization and metastatization were evaluated. Control specimens developed well vascularized tumors and lung metastases, whereas in Ned-19-treated mice tumor growth and vascularization as well as lung metastases were strongly inhibited. In vitro experiments showed that Ned-19 treatment controls the growth of B16 cells in vitro, their migratory ability, adhesive properties and VEGFR2 expression, indicating NAADP involvement in intercellular autocrine signaling. To this regard, Ca2+ imaging experiments showed that the response of B16 cells to VEGF stimulation is NAADP-dependent. The whole of these observations indicate that NAADP-controlled Ca2+ signaling can be relevant not only for neoangiogenesis but also for direct control of tumor cells. PMID:26733361

  14. Experiences in Disseminating Evidence-Based Prevention Programs in a Real-World Setting.

    PubMed

    Frantz, Inga; Stemmler, Mark; Hahlweg, Kurt; Plück, Julia; Heinrichs, Nina

    2015-08-01

    The primary aim of family-based prevention programs is to promote children's health. Unfortunately, it is difficult to reach families with such evidence-based prevention programs (EBP). Therefore, implementing EBP on a population level could be a promising approach to reach more families, including those faced with socioeconomic challenges who are usually less likely to participate in randomized controlled trials (RCT). Is a population rollout appropriate to reach more and different families than those participating in RCT, especially those representative of the target population? We implemented three EBP in a city in an uncontrolled trial. The effects of this population rollout were tracked on the level of the participating families and on the level of all families living in the city. More than 3480 families (30 % of the population) with children up to 12 years of age participated based on practitioner report. Analyses indicate that a greater percentage of low socioeconomic-status families attended a program compared with a randomly surveyed sample from the city's general population. The sizes of the within-subject effect for parental strategies, child behavior problems, and children's quality of life for a subsample of n = 411 families were similar to those of other uncontrolled EBP studies. The study contributes to highly needed type 2 translation research. The population-based dissemination of EBP could be a promising approach to reach families at risk. However, there are considerable barriers to the implementation process, which currently limit the effectiveness of this rollout in a community.

  15. Development of a Model Research and Development Information Dissemination Program for the Kentucky Bureau of Vocational Education: The Omnibus Dissemination Program.

    ERIC Educational Resources Information Center

    Sims, E. Norman

    As a solution to the problem of disseminating information from research and development projects into the field, this project examined a number of diffusion models, developed the Omnibus Model, and tested it. The Omnibus Model consists of eight different action blocks. First, information is acquired both selectively and non-selectively, and then…

  16. Coalition Warfare Program (CWP): secure policy controlled information query and dissemination over a Bices network

    NASA Astrophysics Data System (ADS)

    Toth, Andrew; Pham, Tien; Karr, Todd; Bent, Graham; Harries, Dominic; Knox, Alan

    2013-05-01

    In 2006, the US Army Research Laboratory (ARL) and the UK Ministry of Defence (MoD) established a collaborative research alliance with academia and industry, called the International Technology Alliance (ITA) to address fundamental issues concerning Network and Information Sciences. Under the ITA research program, a US-UK transition project on "ITA Policy Controlled Information Query and Dissemination" was funded in 2011 by OSD's Coalition Warfare Program (CWP). The goal of this CWP project is to develop an extensible capability of performing distributed federated query and information dissemination across a coalition network of distributed disparate data/information sources with access­ controlled policies. The CWP project is lead by US Army Research Laboratory (ARL) and UK Defence Science Technology Laboratory (Dstl) with software development by IBM UK and IBM US. The CWP project exploits two key technology components developed within the ITA, namely the Gaian Database and integrated Access Policy Decision and Enforcement mechanisms. The Gaian Database (GaianDB) is a Dynamic Distributed Federated Database (DDFD) that addresses a need to share information among coalition members by providing a means for policy-controlled access to data across a network of heterogeneous data sources. GaianDB implements a SQL-compliant Store-Locally-Query-Anywhere (SLQA) approach providing software applications with global access to data from any node in the database network via standard SQL queries. Security policy is stored locally and enforced at the database node level, reducing potential for unauthorized data access and waste of network bandwidth. A key metric of success for a CWP project is the transition of coalition-related technology from TRL-3 or 4 to TRL-6 or higher. Thus, the end goal of this CWP project was to demonstrate the GaianDB and policy technology within an operational environment at the NATO Intelligence Fusion Centre (NIFC) at Molesworth RAF. An initial

  17. Neuroblastoma cells undergo transcriptomic alterations upon dissemination into the bone marrow and subsequent tumor progression.

    PubMed

    Rifatbegovic, Fikret; Frech, Christian; Abbasi, M Reza; Taschner-Mandl, Sabine; Weiss, Tamara; Schmidt, Wolfgang M; Schmidt, Iris; Ladenstein, Ruth; Ambros, Inge M; Ambros, Peter F

    2017-09-16

    Neuroblastoma is the most common extracranial solid tumor in childhood. The vast majority of metastatic (M) stage patients present with disseminated tumor cells (DTCs) in the bone marrow (BM) at diagnosis and relapse. Although these cells represent a major obstacle in the treatment of neuroblastoma patients, insights into their expression profile remained elusive. The present RNA-Seq study of stage 4/M primary tumors, enriched BM-derived diagnostic and relapse DTCs, as well as the corresponding BM-derived mononuclear cells (MNCs) from 53 patients revealed 322 differentially expressed genes in DTCs as compared to the tumors (q < 0.001, |log2 FC|>2). Particularly, the levels of transcripts encoded by mitochondrial DNA were elevated in DTCs, whereas, for example, genes involved in angiogenesis were downregulated. Furthermore, 224 genes were highly expressed in DTCs and only slightly, if at all, in MNCs (q < 8 × 10(-75) log2 FC > 6). Interestingly, we found the transcriptome of relapse DTCs largely resembling those of diagnostic DTCs with only 113 differentially expressed genes under relaxed cut-offs (q < 0.01, |log2 FC|>0.5). Notably, relapse DTCs showed a positional enrichment of 31 downregulated genes on chromosome 19, including five tumor suppressor genes: SIRT6, BBC3/PUMA, STK11, CADM4 and GLTSCR2. This first RNA-Seq analysis of neuroblastoma DTCs revealed their unique expression profile in comparison to the tumors and MNCs, and less pronounced differences between diagnostic and relapse DTCs. The latter preferentially affected downregulation of genes encoded by chromosome 19. As these alterations might be associated with treatment failure and disease relapse, further functional studies on DTCs should be considered. © 2017 The Authors International Journal of Cancer published by John Wiley & Sons Ltd on behalf of UICC.

  18. Fossil energy program. Progress report, July 1980

    SciTech Connect

    McNeese, L. E.

    1980-10-01

    This report - the seventy-second of a series - is a compendium of monthly progress reports for the ORNL research and development programs that are in support of the increased utilization of coal and other fossil fuel alternatives to oil and gas as sources of clean energy. The projects reported this month include those for coal conversion development, chemical research and development, materials technology, component development and process evaluation, technical support to major liquefaction projects, process and program analysis, fossil energy environmental analysis, coal preparation and waste utilization, coal preparation plant automation, atmospheric fluidized bed coal combustor for cogeneration, technical support to the TVA fluidized bed combustion demonstration plant program, fossil energy applications assessments, performance assurance system support for fossil energy projects, international assessment of atmospheric fluidized bed combustion technology, and PFBC systems analysis.

  19. MGMT promoter methylation is associated with temozolomide response and prolonged progression-free survival in disseminated cutaneous melanoma.

    PubMed

    Tuominen, Rainer; Jewell, Rosalyn; van den Oord, Joost J; Wolter, Pascal; Stierner, Ulrika; Lindholm, Christer; Hertzman Johansson, Carolina; Lindén, Diana; Johansson, Hemming; Frostvik Stolt, Marianne; Walker, Christy; Snowden, Helen; Newton-Bishop, Julia; Hansson, Johan; Egyházi Brage, Suzanne

    2015-06-15

    To investigate the predictive and prognostic value of O(6) -methylguanine DNA methyltransferase (MGMT) inactivation by analyses of promoter methylation in pretreatment tumor biopsies from patients with cutaneous melanoma treated with dacarbazine (DTIC) or temozolomide (TMZ) were performed. The patient cohorts consisted of Belgian and Swedish disseminated melanoma patients. Patients were subdivided into those receiving single-agent treatment with DTIC/TMZ (cohort S, n = 74) and those treated with combination chemotherapy including DTIC/TMZ (cohort C, n = 79). Median follow-up was 248 and 336 days for cohort S and cohort C, respectively. MGMT promoter methylation was assessed by three methods. The methylation-related transcriptional silencing of MGMT mRNA expression was assessed by real-time RT-PCR. Response to chemotherapy and progression-free survival (PFS) and overall survival were correlated to MGMT promoter methylation status. MGMT promoter methylation was detected in tumor biopsies from 21.5 % of the patients. MGMT mRNA was found to be significantly lower in tumors positive for MGMT promoter methylation compared to tumors without methylation in both treatment cohorts (p < 0.005). DTIC/TMZ therapy response rate was found to be significantly associated with MGMT promoter methylation in cohort S (p = 0.0005), but did not reach significance in cohort C (p = 0.16). Significantly longer PFS was observed among patients with MGMT promoter-methylated tumors (p = 0.002). Multivariate Cox regression analysis identified presence of MGMT promoter methylation as an independent variable associated with longer PFS. Together, this implies that MGMT promoter methylation is associated with response to single-agent DTIC/TMZ and longer PFS in disseminated cutaneous melanoma.

  20. Radical cystectomy in patients with disseminated disease: An assessment of perioperative outcomes using the National Surgical Quality Improvement Program database

    PubMed Central

    Wallis, Christopher; Khana, Suneil; Hajiha, Mohammad; Nam, Robert K.; Satkunasivam, Raj

    2017-01-01

    Introduction We sought to determine the effect of the presence of disseminated disease on perioperative outcomes following radical cystectomy for bladder cancer. Methods We identified 4108 eligible patients who underwent radical cystectomy for bladder cancer using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database. We matched patients with disseminated cancer at the time of surgery to those without disseminated cancer using propensity scores. The primary outcome of interest was major complications (death, reoperation, cardiac or neurological event). Secondary outcomes included pulmonary, infectious thromboembolic, and bleeding complications, in addition to prolonged length of stay. Generalized estimating equations were used to examine the association between disseminated cancer and the development of complications. Results Following propensity score matching and adjusting for the type of urinary diversion, radical cystectomy in patients with disseminated disease was associated with a significant increase in major complications (8.6% vs. 4.0%; odds ratio [OR] 2.50; 95% confidence interval [CI] 1.02–6.11; p=0.045). The presence of disseminated disease was associated with an increase in pulmonary complications (5.8% vs. 1.2%; OR 5.17. 95% CI 1.00–26.66. p=0.049), but not infectious complications, venous thromboembolism, bleeding requiring transfusion, and prolonged length of stay (p values 0.07–0.79). Conclusions Patients with disseminated cancer undergoing cystectomy are more likely to experience major and pulmonary complications. The strength of these conclusions is limited by sample size, selection bias inherent in observational data, and a lack of specific oncological detail in the database. PMID:28798823

  1. Radical cystectomy in patients with disseminated disease: An assessment of perioperative outcomes using the National Surgical Quality Improvement Program database.

    PubMed

    Wallis, Christopher; Khana, Suneil; Hajiha, Mohammad; Nam, Robert K; Satkunasivam, Raj

    2017-08-01

    We sought to determine the effect of the presence of disseminated disease on perioperative outcomes following radical cystectomy for bladder cancer. We identified 4108 eligible patients who underwent radical cystectomy for bladder cancer using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database. We matched patients with disseminated cancer at the time of surgery to those without disseminated cancer using propensity scores. The primary outcome of interest was major complications (death, reoperation, cardiac or neurological event). Secondary outcomes included pulmonary, infectious thromboembolic, and bleeding complications, in addition to prolonged length of stay. Generalized estimating equations were used to examine the association between disseminated cancer and the development of complications. Following propensity score matching and adjusting for the type of urinary diversion, radical cystectomy in patients with disseminated disease was associated with a significant increase in major complications (8.6% vs. 4.0%; odds ratio [OR] 2.50; 95% confidence interval [CI] 1.02-6.11; p=0.045). The presence of disseminated disease was associated with an increase in pulmonary complications (5.8% vs. 1.2%; OR 5.17. 95% CI 1.00-26.66. p=0.049), but not infectious complications, venous thromboembolism, bleeding requiring transfusion, and prolonged length of stay (p values 0.07-0.79). Patients with disseminated cancer undergoing cystectomy are more likely to experience major and pulmonary complications. The strength of these conclusions is limited by sample size, selection bias inherent in observational data, and a lack of specific oncological detail in the database.

  2. SELECTIVE DISSEMINATION OF INFORMATION IN PRACTICE, SURVEY OF OPERATIONAL AND EXPERIMENTAL SDI PROGRAMS.

    ERIC Educational Resources Information Center

    DOWNIE, CURRIE S.; HOSHOVSKY, ALEXANDER G.

    AN OVERVIEW OF THE OPERATIONAL AND EXPERIMENTAL SYSTEMS ESTABLISHED FOR THE SELECTIVE DISSEMINATION OF SCIENTIFIC AND TECHNICAL INFORMATION (SDI) IS PRESENTED. AN ATTEMPT HAS ALSO BEEN MADE TO IDENTIFY THE TRENDS WHICH MAY SHAPE THE FUTURE DEVELOPMENT OF THE SELECTIVE DISSEMINATION PROCEDURES. THE REPORT IS BASED IN PART ON THE EXISTING SDI…

  3. Key Issues for Navigation and Time Dissemination in NASA's Space Exploration Program

    NASA Technical Reports Server (NTRS)

    Nelson, R. A.; Brodsky, B.; Oria, A. J.; Connolly, J. W.; Sands, O. S.; Welch, B. W.; Ely T.; Orr, R.; Schuchman, L.

    2006-01-01

    The renewed emphasis on robotic and human missions within NASA's space exploration program warrants a detailed consideration of how the positions of objects in space will be determined and tracked, whether they be spacecraft, human explorers, robots, surface vehicles, or science instrumentation. The Navigation Team within the NASA Space Communications Architecture Working Group (SCAWG) has addressed several key technical issues in this area and the principle findings are reported here. For navigation in the vicinity of the Moon, a variety of satellite constellations have been investigated that provide global or regional surface position determination and timely services analogous to those offered by GPS at Earth. In the vicinity of Mars, there are options for satellite constellations not available at the Moon due to the gravitational perturbations from Earth, such as two satellites in an aerostationary orbit. Alternate methods of radiometric navigation as considered, including one- and two-way signals, as well as autonomous navigation. The use of a software radio capable of receiving all available signal sources, such as GPS, pseudolites, and communication channels, is discussed. Methods of time transfer and dissemination are also considered in this paper.

  4. Disseminating contingency management: impacts of staff training and implementation at an opiate treatment program.

    PubMed

    Hartzler, Bryan; Jackson, T Ron; Jones, Brinn E; Beadnell, Blair; Calsyn, Donald A

    2014-04-01

    Guided by a comprehensive implementation model, this study examined training/implementation processes for a tailored contingency management (CM) intervention instituted at a Clinical Trials Network-affiliate opioid treatment program (OTP). Staff-level training outcomes (intervention delivery skill, knowledge, and adoption readiness) were assessed before and after a 16-hour training, and again following a 90-day trial implementation period. Management-level implementation outcomes (intervention cost, feasibility, and sustainability) were assessed at study conclusion in a qualitative interview with OTP management. Intervention effectiveness was also assessed via independent chart review of trial CM implementation vs. a historical control period. Results included: 1) robust, durable increases in delivery skill, knowledge, and adoption readiness among trained staff; 2) positive managerial perspectives of intervention cost, feasibility, and sustainability; and 3) significant clinical impacts on targeted patient indices. Collective results offer support for the study's collaborative intervention design and the applied, skills-based focus of staff training processes. Implications for CM dissemination are discussed.

  5. Dissemination of an evidence-based program to reduce fear of falling, South Carolina, 2006-2009.

    PubMed

    Ullmann, Gerhild; Williams, Harriet G; Plass, Cora F

    2012-01-01

    Falls among older adults are a serious public health issue, and fear of falling can limit mobility, which in turn increases fall risk. A Matter of Balance/Volunteer Lay Leader Model is an evidence-based program designed to address fear of falling. The objective of this study was to describe implementation, dissemination, and outcomes of this program in 3 regions of South Carolina with a predominantly African American and largely underserved population. We developed partnerships throughout the state, organized master and lay leader trainings, and documented numbers of lay leaders, programs offered, demographic characteristics of participants, program fidelity, and attendance. Outcome measures were self-reported confidence to prevent and manage falls and a quantitative measure of functional mobility. Both measures were assessed at baseline and after program completion. Older adults (N = 235) attended 18 classes at 16 sites. Barriers to implementation were program teams' limited familiarity with the concept of evidence-based programs and the importance of adhering to program content. Facilitators were state-level leadership and a history of state, regional, and local groups collaborating successfully on other projects. Outcomes indicated greater confidence in managing falls and carrying out activities of daily living. Mobility improved significantly, suggesting a reduced risk for falls. Evidence-based programs such as A Matter of Balance/Volunteer Lay Leader Model can be successfully disseminated in underserved areas. Outcomes indicate that participation in fall prevention programs can benefit groups of predominantly African American older adults.

  6. Dissemination of an Evidence-based Program to Reduce Fear of Falling, South Carolina, 2006-2009

    PubMed Central

    Ullmann, Gerhild; Plass, Cora F.

    2012-01-01

    Introduction Falls among older adults are a serious public health issue, and fear of falling can limit mobility, which in turn increases fall risk. A Matter of Balance/Volunteer Lay Leader Model is an evidence-based program designed to address fear of falling. The objective of this study was to describe implementation, dissemination, and outcomes of this program in 3 regions of South Carolina with a predominantly African American and largely underserved population. Methods We developed partnerships throughout the state, organized master and lay leader trainings, and documented numbers of lay leaders, programs offered, demographic characteristics of participants, program fidelity, and attendance. Outcome measures were self-reported confidence to prevent and manage falls and a quantitative measure of functional mobility. Both measures were assessed at baseline and after program completion. Results Older adults (N = 235) attended 18 classes at 16 sites. Barriers to implementation were program teams' limited familiarity with the concept of evidence-based programs and the importance of adhering to program content. Facilitators were state-level leadership and a history of state, regional, and local groups collaborating successfully on other projects. Outcomes indicated greater confidence in managing falls and carrying out activities of daily living. Mobility improved significantly, suggesting a reduced risk for falls. Conclusion Evidence-based programs such as A Matter of Balance/Volunteer Lay Leader Model can be successfully disseminated in underserved areas. Outcomes indicate that participation in fall prevention programs can benefit groups of predominantly African American older adults. PMID:22632740

  7. [Cutaneous signs of Noonan's syndrome. Apropos of a case with ulerythema ophyogenes, disseminated pilar and sudoral keratosis and progressive alopecia].

    PubMed

    Grob, J J; Laure, M; Berge, G; Taramasco, M; Bore, P; Benderitter, T; Andrac, L; Collet, A M; Bonerandi, J J

    1988-01-01

    A case of typical Noonan syndrome (NS) with eye abnormalities, pterygium colli, cryptorchid testes, lymphoedema and asymmetrical cardiac septal hypertrophy is reported in a 8-month old infant. This case was particularly interesting since it included skin manifestations which enabled an early diagnosis to be made. Ulerythema ophryogenes has already been proposed as a cutaneous marker of NS, but the keratinization disorders in our patient also included disseminated keratosis of both hair follicles and sweat glands orifices. Abnormally brittle short curly hair has already been reported, but our patient exhibited progressive alopecia which is very rare in NS. Biochemical hair analysis did not show any abnormalities of aminoacids. All these features were suggestive of keratosis follicularis spinulosa decalvans. It therefore seems very likely that NS is associated with keratinization disorders but ulerythema ophryogenes might only be the limited form of these disorders. The other skin manifestations of NS are reviewed. Since the patient had 4 "café au lait" spots, the relation of NS with Von Recklinghausen syndrome, and neurofibromatosis-Noonan syndrome is discussed. Watson's Leopard and cardio-facial syndromes overlap with, and may represent subsets of NS.

  8. Progressive intraparenchymal lung nodules dissemination in a heavy smoker and seropositive rheumatoid arthritis suspected of tuberculosis relapse.

    PubMed

    Arghir, Oana Cristina; Niţu, Mimi; Trenchea, Mihaela; Ciobotaru, Camelia

    2013-01-01

    Anthony Caplan first described rheumatoid lung nodules associated with pneumoconiosis in coal-miners (Caplan, 1953). Intraparenchymal lung nodules were later described in rheumatoid arthritis (RA) patients who were never exposed to coal dust and/or without pneumoconiosis. Rheumatoid lung nodules are usually detected in unselected patients: 0.2% in chest radiography and 4% in high-resolution computed tomography (Nannini et al., 2008). Patients could be reluctant to perform surgical lung biopsy for an accurate histopathological diagnosis. We present a peculiar association between a seropositive RA and a presumptive active tuberculosis (TB) disease in a 59-year-old male patient, ex-smoker with a previously healed pulmonary TB disease. The purpose of this report is to describe an unusual case of a presumptive relapse of the nodular TB disease, which progressed to an extensive nodular bilateral dissemination under anti-tuberculosis therapy, mimicking a metastatic carcinoma. The diagnosis of rheumatoid necrobiotic lung nodules was confirmed after open biopsy left pulmonary was performed. Formalin-fixed paraffin-embedded pulmonary rheumatoid nodules were processed for histology and stained with Masson's trichrome. Central structure of the removed pulmonary nodules is typical of a rheumatoid nodule with central necrosis surrounded by a palisade of macrophages. The accumulation of anthracotic pigment was noticed inside the pulmonary nodules in a RA patient without professional exposure to coal or mineral dust. This rare entity is an appearance of the rheumatoid nodules lung syndrome and anthracosis in a heavy tobacco former smoker.

  9. Perioperative outcomes following radical prostatectomy for patients with disseminated cancer: An analysis of the National Surgical Quality Improvement Program database

    PubMed Central

    Satkunasivam, Raj; Wallis, Christopher J.D.; Byrne, James; Hoffman, Azik; Cheung, Douglas C.; Kulkarni, Girish S.; Nathens, Avery B.; Nam, Robert K.

    2016-01-01

    Introduction We sought to determine whether patients undergoing radical prostatectomy (RP) in the context of disseminated cancer have higher 30-day complications. Methods We conducted a retrospective cohort study of the National Surgical Quality Improvement Program (NSQIP) database. Men undergoing RP (from January 1, 2005 to December 31, 2014) for prostate cancer were identified and stratified by presence (n=97) or absence (n=27 868) of disseminated cancer. The primary outcome was major complications (death, re-operation, cardiac or neurologic events) within 30 days of surgery. Secondary outcomes included pulmonary, infectious, venous thromboembolic, and bleeding complications; prolonged length of stay; and concomitant procedures (bowel-related, cystectomy, urinary diversion, and major ureteric reconstruction). Odds ratios (OR) for each complication were calculated using univariable logistic regression. Results We did not identify a difference in major complication rates (OR 2.26, 95% confidence interval [CI] 0.71–7.16). Patients with disseminated cancer had increased risk of venous thromboembolic events (OR 3.30, 95% CI 1.04–10.48) and transfusion (OR 2.45, 95% CI 1.18–5.05), but similar odds of pulmonary and infectious complications and length of stay. Bowel procedures were rare, however, a significantly higher proportion of patients with disseminated cancer required bowel procedures (2.1% vs. 0.3%; p=0.03). Patients with disseminated cancer undergoing RP had greater comorbidities and higher predicted probability of morbidity and mortality. This study is limited by its retrospective design, lack of cancer-specific variables, and prostatectomy-specific complications. Conclusions RP in the context of disseminated cancer may be associated with increased perioperative complications. Caution should be exercised in embarking on this practice outside of clinical trials. PMID:28096918

  10. Progress of the RERTR program in 2001.

    SciTech Connect

    Travelli, A.

    2002-03-07

    This paper describes the 2001 progress achieved by the Reduced Enrichment for Research and Test Reactors (RERTR) Program in collaboration with its many international partners. Postirradiation examinations of microplates have continued to reveal excellent irradiation behavior of U-Mo dispersion fuels in a variety of compositions and irradiating conditions. Irradiation of two new batches of miniplates of greater sizes was completed in the ATR to investigate the swelling behavior of these fuels under prototypic conditions. These materials hold the promise of achieving the program goal of developing LEU research reactor fuels with uranium densities in the 8-9 g/cm{sup 3} range. Qualification of the U-Mo dispersion fuels has been delayed by a patent issue involving KAERI. Test fuel elements with uranium density of 6 g/cm{sup 3} are being fabricated by BWXT and are expected to begin undergoing irradiation in the HFR-Petten reactor around March 2003, with a goal of qualifying this fuel by mid-2005. U-Mo fuel with uranium density of 8-9 g/cm{sup 3} is expected to be qualified by mid-2007. Final irradiation tests of LEU {sup 99}Mo targets in the RAS-GAS reactor at BATAN, in Indonesia, had to be postponed because of the 9/11 attacks, but the results collected to date indicate that these targets will soon be ready for commercial production. Excellent cooperation is also in progress with the CNEA in Argentina, MDSN/AECL in Canada, and ANSTO in Australia. Irradiation testing of five WWR-M2 tube-type fuel assemblies fabricated by the NZChK and containing LEU UO{sub 2} dispersion fuel was successfully completed within the Russian RERTR program. A new LEU U-Mo pin-type fuel that could be used to convert most Russian-designed research reactors has been developed by VNIINM and is ready for testing. Four additional shipments containing 822 spent fuel assemblies from foreign research reactors were accepted by the U.S. by September 30, 2001. Altogether, 4,562 spent fuel assemblies from

  11. Rupture of a spinal dermoid cyst may lead to dissemination and progress of Fatty tissue in the central spinal canal and intracranial subarachnoid space. A case report.

    PubMed

    Kabbasch, Christoph; Dorn, Franziska; Mpotsaris, Anastasios; Weber, Christoph; Liebig, Thomas

    2014-12-01

    Intradural dermoid cysts may rupture and subsequent subarachnoid dissemination of lipid droplets has been described before. However, the rupture of a spinal dermoid cyst into the central spinal canal is a rare entity. In this context, dissemination of fat into the intracranial subarachnoid space with local progression is a peculiar finding that, to the best of our knowledge, has not been published so far. We describe the case of a 28-year-old man with a dermoid cyst at the upper lumbar level as part of a complex congenital craniospinal malformation, presenting with new unspecific neurologic symptoms. CT and MRI revealed disseminated intraventricular and subarachnoid lipid droplets intracranially and in the spine not present on previous CT and MRI scans obtained eight years earlier. Thus, repeated rupture of a spinal dermoid cyst with subarachnoid spread and/or secondary proliferation should be suspected.

  12. Developing educational competencies for dissemination and implementation research training programs: an exploratory analysis using card sorts.

    PubMed

    Padek, Margaret; Colditz, Graham; Dobbins, Maureen; Koscielniak, Nikolas; Proctor, Enola K; Sales, Anne E; Brownson, Ross C

    2015-08-12

    With demand increasing for dissemination and implementation (D&I) training programs in the USA and other countries, more structured, competency-based, and tested curricula are needed to guide training programs. There are many benefits to the use of competencies in practice-based education such as the establishment of rigorous standards as well as providing an additional metrics for development and growth. As the first aim of a D&I training grant, an exploratory study was conducted to establish a new set of D&I competencies to guide training in D&I research. Based upon existing D&I training literature, the leadership team compiled an initial list of competencies. The research team then engaged 16 additional colleagues in the area of D&I science to provide suggestions to the initial list. The competency list was then additionally narrowed to 43 unique competencies following feedback elicited from these D&I researchers. Three hundred additional D&I researchers were then invited via email to complete a card sort in which the list of competencies were sorted into three categories of experience levels. Participants had previous first-hand experience with D&I or knowledge translation training programs in the past. Participants reported their self-identified D&I expertise level as well as the country in which their home institution is located. A mean score was calculated for each competency based on their experience level categorization. From these mean scores, beginner-, intermediate-, and advanced-level tertiles were created for the competencies. The card sort request achieved a 41 % response rate (n = 124). The list of 43 competencies was organized into four broad domains and sorted based on their experience level score. Eleven competencies were classified into the "Beginner" category, 27 into "Intermediate," and 5 into "Advanced." Education and training developers can use this competency list to formalize future trainings in D&I research, create more evidence

  13. Dissemination and Implementation of a Financial Management Program for Adult/Young Farmers in Vocational Agriculture Programs in Missouri. Final Report.

    ERIC Educational Resources Information Center

    Denker, Robert; Stewart, Bob R.

    In addition to an eight-page narrative, this final report contains materials and products from phase 2 of a project to develop, disseminate, and implement a three-year sequenced individualized and group instructional program in financial management for adult/young farmers in vocational agriculture. The narrative section discusses the four project…

  14. Successful dissemination of a community-based strength training program for older adults by peer and professional leaders: the people exercising program

    USDA-ARS?s Scientific Manuscript database

    OBJECTIVES: To determine the feasibility of a model for disseminating community-based strength training programs for older adults through leadership training of both laypersons or "peers" and health and fitness professionals. DESIGN: Longitudinal study conducted from January 2005 to December 2006....

  15. Dissemination and Implementation of a Financial Management Program for Adult/Young Farmers in Vocational Agriculture Programs in Missouri. Final Report.

    ERIC Educational Resources Information Center

    Denker, Robert; Stewart, Bob R.

    In addition to an eight-page narrative, this final report contains materials and products from phase 2 of a project to develop, disseminate, and implement a three-year sequenced individualized and group instructional program in financial management for adult/young farmers in vocational agriculture. The narrative section discusses the four project…

  16. Proceedings of the Office of Special Education Programs' Annual Technical Assistance and Dissemination Meeting (6th, Washington, DC, January 16-18, 1996).

    ERIC Educational Resources Information Center

    Special Education Programs (ED/OSERS), Washington, DC.

    This document presents the proceedings for the Office of Special Education Programs' 6th Annual Technical Assistance and Dissemination Meeting held on January 16-18, 1996, in Washington, DC. Conference discussions centered around changing expectations for local and state education agencies and technical assistance and dissemination (TA&D)…

  17. Cerebrospinal fluid dissemination of anaplastic intraventricular meningioma: report of a case presenting with progressive brainstem dysfunction and multiple cranial nerve palsies.

    PubMed

    Fujimaki, Motoki; Takanashi, Masashi; Kobayashi, Manami; Wada, Kei-ichiro; Machida, Yutaka; Kondo, Akihide; Hattori, Nobutaka; Miwa, Hideto

    2016-05-31

    It is extremely rare to see cerebrospinal fluid dissemination of intraventricular meningioma, particularly with the development of acute, progressive brainstem/cerebellar dysfunction with an absence of mass formation in the corresponding anatomical sites. An 81-year-old man was admitted because of double vision, right facial nerve palsy and truncal ataxia. Brain magnetic resonance imaging showed normal findings except for a tumor mass in the left lateral ventricle, which had been noted over 6 months previously. The patient developed hiccups, hyperventilation, and drowsiness, which worsened progressively, and did not respond to corticosteroid or intraventricular immunoglobulin therapy. Cerebrospinal fluid study revealed a mild elevation of protein, and cytology was negative. The patient died and an autopsy was performed. Postmortem investigation disclosed a malignant transformation of benign fibroid meningioma with cerebrospinal fluid dissemination of the malignant cells, diversely involving the surface of brainstem, cerebellum, and spinal cords, secondarily resulting in extensive ischemia in the brain parenchyma by vessel occlusion. If a patient with an intraventricular tumor develops acute, progressive neurological symptoms, the possibility that it is be caused by cerebrospinal fluid dissemination of tumor cells, after malignant transformation, should be considered.

  18. Linking agents' activities and communication patterns in a study of the dissemination of an effective skin cancer prevention program.

    PubMed

    Hall, Dawn; Dubruiel, Nicole; Elliott, Tom; Glanz, Karen

    2009-01-01

    Linking agents connect program developers with end users, enhancing implementation and sustainability of health promotion programs. However, little is known about how linkage systems work in practice and research settings. This article describes the activities and communication patterns of field coordinators in a 4-year, national study of the dissemination of an effective skin cancer prevention program. Descriptive and content analyses were completed for all e-mails between field coordinators and program staff and for field coordinator activity logs. A total of 5,215 e-mails were sent to or from 62 field coordinators from 2003 to 2006. E-mails most often concerned program administration, data collection, and management of program materials. The most common activities recorded in activity logs were communication with program staff and study sites, management of surveys, and delivery and management of program materials. Field coordinators carried out activities related to program administration and data collection across a large number of study sites. The high volume of e-mails and their emphasis on program administration issues demonstrate the importance of communication between program staff and field coordinators. It is recommended that public health researchers and practitioners implement similar linkage systems when taking effective programs to scale.

  19. Contextual Factors Influencing Readiness for Dissemination of Obesity Prevention Programs and Policies

    ERIC Educational Resources Information Center

    Dreisinger, Mariah L.; Boland, Elizabeth M.; Filler, Carl D.; Baker, Elizabeth A.; Hessel, Amy S.; Brownson, Ross C.

    2012-01-01

    Within the realm of obesity prevention research, there have been many promising interventions to improve physical activity and nutrition among diverse target populations. However, very little information is known about the dissemination and replication of these interventions. In 2007 and 2008 as part of a larger obesity prevention initiative,…

  20. Streaming the Archives: Repurposing Systems to Advance a Small Media Digitization and Dissemination Program

    ERIC Educational Resources Information Center

    Anderson, Talea

    2015-01-01

    In 2013-2014, Brooks Library at Central Washington University (CWU) launched library content in three systems: a digital asset-management system, an institutional repository (IR), and a web-based discovery layer. In early 2014, the archives at the library began to use these systems to disseminate media recently digitized from legacy formats. As…

  1. Contextual Factors Influencing Readiness for Dissemination of Obesity Prevention Programs and Policies

    ERIC Educational Resources Information Center

    Dreisinger, Mariah L.; Boland, Elizabeth M.; Filler, Carl D.; Baker, Elizabeth A.; Hessel, Amy S.; Brownson, Ross C.

    2012-01-01

    Within the realm of obesity prevention research, there have been many promising interventions to improve physical activity and nutrition among diverse target populations. However, very little information is known about the dissemination and replication of these interventions. In 2007 and 2008 as part of a larger obesity prevention initiative,…

  2. Large Scale Dissemination and Community Implementation of Pivotal Response Treatment: Program Description and Preliminary Data

    ERIC Educational Resources Information Center

    Bryson, Susan E.; Koegel, Lynn K.; Koegel, Robert L.; Openden, Daniel; Smith, Isabel M.; Nefdt, Nicolette

    2007-01-01

    This paper describes a collaborative effort aimed at province-wide dissemination and implementation of pivotal response treatment (PRT) for young children with autism spectrum disorder (ASD) in Nova Scotia, Canada. Three critical components of the associated training model are described: (1) direct training of treatment teams (parents, one-to-one…

  3. The Role, Purpose and Program of the Unit for Dissemination: A Position Paper. Revised.

    ERIC Educational Resources Information Center

    Sims, E. Norman

    To alleviate the time lag between the conception and the implementation of educational innovation, the Unit for Dissemination has been formed by the Kentucky Department of Education. Within the goals of fostering awareness and interest in innovation and of spreading innovation from field test to ultimate user, the Unit has defined objectives which…

  4. Streaming the Archives: Repurposing Systems to Advance a Small Media Digitization and Dissemination Program

    ERIC Educational Resources Information Center

    Anderson, Talea

    2015-01-01

    In 2013-2014, Brooks Library at Central Washington University (CWU) launched library content in three systems: a digital asset-management system, an institutional repository (IR), and a web-based discovery layer. In early 2014, the archives at the library began to use these systems to disseminate media recently digitized from legacy formats. As…

  5. 'There is a dependent patient in our home': designing and disseminating a family caregiving program through YouTube.

    PubMed

    Abu Kamel, Andaleeb

    2016-06-01

    Family members play a major role in providing care for older people and long-term dependent patients, especially in developing countries where there is a lack of specialized nursing homes and specialized home-visiting programs. Family members are rarely provided with sufficient information or training to provide home care for their dependent relatives. There are inadequate home caregiving educational resources directed to Arabic-speaking caregivers, either in written or in audiovisual presentations. The aims of the present study were (i) to present the process of designing a caregiving educational program entitled 'there is a dependent patient in our home', with an intention to be culturally and linguistically appropriate for a specific Arab-speaking population, and (ii) to present the experience of disseminating the program through YouTube, to be accessible for a wide range of caregivers. The program was a product of a process involving seven phases, starting with a review of the literature and ending with disseminating 17 short 'caregiving' videos on YouTube, the most popular video-sharing website. The program presented necessary skills, instructions, and information that enabled caregivers to provide safe and competent daily caring activities for their functionally dependent relative or older adults at home. The program was registered in the Jordan National Library. After 2 months of broadcasting it on YouTube, the number of views exceeded 6800. Many constructive comments were received from caregivers. Language, simplicity, and attractiveness of the program were judged as the areas of satisfaction by the viewers, whereas lack of a few topics such as verbal communication with patients and dealing with daily caregivers' burden and stressors were the main reasons of dissatisfaction. This program was an endeavor to provide the Arabic library with a home caregiving resource. Adequate advertisement of the program would encourage health providers to search for and use

  6. Human Genome Program Report. Part 1, Overview and Progress

    DOE R&D Accomplishments Database

    1997-11-01

    This report contains Part 1 of a two-part report to reflect research and progress in the U.S. Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 1 consists of the program overview and report on progress.

  7. Human genome program report. Part 1, overview and progress

    SciTech Connect

    1997-11-01

    This report contains Part 1 of a two-part report to reflect research and progress in the U.S. Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 1 consists of the program overview and report on progress.

  8. AR and TD Fossil Energy Materials Program. Quarterly progress report for the period ending December 31, 1981

    SciTech Connect

    Not Available

    1982-04-01

    The ORNL Fossil Energy Materials Program Office compiles and issues this combined quarterly progress report from camera-ready copies submitted by each of the participating subcontractor organizations. This report of activities on the program is organized in accordance with a work breakdown structure defined in the AR and TD Fossil Energy Materials Program Plan for FY 1982-1986 in which projects are organized according to fossil energy technologies. This report is divided into parts and chapters with each part describing projects related to a particular fossil energy technology. Chapters within a part provide details of the various projects associated with that technology. We hope this series of AR and TD Fossil Energy Materials Program quarterly progress reports will aid in the dissemination of information developed on the program. Plans for the program will be issued annually. A draft of the program plan for FY 1982 to 1986 has been prepared and is in the review process. The implementation of these plans will be reflected by these quarterly progress reports, and this dissemination of information will bw augmented by topical or final reports as appropriate.

  9. In Preparation of the Nationwide Dissemination of the School-Based Obesity Prevention Program DOiT: Stepwise Development Applying the Intervention Mapping Protocol

    ERIC Educational Resources Information Center

    van Nassau, Femke; Singh, Amika S.; van Mechelen, Willem; Brug, Johannes; Chin A. Paw, Mai J. M.

    2014-01-01

    Background: The school-based Dutch Obesity Intervention in Teenagers (DOiT) program is an evidence-based obesity prevention program. In preparation for dissemination throughout the Netherlands, this study aimed to adapt the initial program and to develop an implementation strategy and materials. Methods: We revisited the Intervention Mapping (IM)…

  10. In Preparation of the Nationwide Dissemination of the School-Based Obesity Prevention Program DOiT: Stepwise Development Applying the Intervention Mapping Protocol

    ERIC Educational Resources Information Center

    van Nassau, Femke; Singh, Amika S.; van Mechelen, Willem; Brug, Johannes; Chin A. Paw, Mai J. M.

    2014-01-01

    Background: The school-based Dutch Obesity Intervention in Teenagers (DOiT) program is an evidence-based obesity prevention program. In preparation for dissemination throughout the Netherlands, this study aimed to adapt the initial program and to develop an implementation strategy and materials. Methods: We revisited the Intervention Mapping (IM)…

  11. Cracow clean fossil fuels and energy efficiency program. Progress report

    SciTech Connect

    1998-10-01

    Since 1990 the US Department of Energy has been involved in a program aimed at reducing air pollution caused by small, coal-fired sources in Poland. The program focuses on the city of Cracow and is designed so that results will be applicable and extendable to the entire region. This report serves both as a review of the progress which has been made to date in achieving the program objectives and a summary of work still in progress.

  12. 77 FR 75441 - Healthy Home and Lead Hazard Control Grant Programs Data Collection; Progress Reporting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... URBAN DEVELOPMENT Healthy Home and Lead Hazard Control Grant Programs Data Collection; Progress... progress of Healthy Homes Demonstration Program, Healthy Homes Technical Studies Program, Lead Base paint Hazard Control program, Lead Hazard Reduction Demonstration Program, Lead Outreach Program, Lead...

  13. Developing an Effective Dissemination Plan.

    ERIC Educational Resources Information Center

    Southwest Educational Development Laboratory, Austin, TX. National Center for the Dissemination of Disability Research.

    This booklet offers guidelines for the development of dissemination strategies, especially those concerned with research and programs. Individual sections address: the importance of including sound dissemination plans in grant proposals, factors found to be closely related to information utilization in the dissemination process, a philosophical…

  14. Design of a Functional Competence Training Program for Development, Dissemination, and Evaluation Personnel at Professional and Paraprofessional Levels in Education. Volumes I and II; Attachments One and Two.

    ERIC Educational Resources Information Center

    Hood, Paul D.; Banathy, Bela H.

    The mission of the Far West Consortium for DD&E training is to design, develop, implement, and evaluate a comprehensive and transportable training program to meet the demand for trained personnel in educational development, dissemination, and evaluation (DD&E). The program provides both preservice training and continuing education to upgrade those…

  15. Comprehensive Offender Program Effort. Final Progress Report.

    ERIC Educational Resources Information Center

    Bagley, Carole A.

    This report summarizes the year's activities of a project at two adult correctional institutions which utilized computers in their educational programs to supplement the existing GED, basic math, language arts, reading, and vocational skills and awareness curriculums. The computer is used as a supplement to the educational programs by providing…

  16. Disseminated sporotrichosis.

    PubMed

    Romero-Cabello, Raúl; Bonifaz, Alexandro; Romero-Feregrino, Raúl; Sánchez, Carlos Javier; Linares, Yancy; Zavala, Jorge Tay; Romero, Leticia Calderón; Romero-Feregrino, Rodrigo; Vega, José T Sánchez

    2011-03-25

    Sporotrichosis is a subacute or chronic infection caused by Sporothrix schenckii. It is a primary cutaneous infection and it has different clinical forms: disseminated by lymphatic vessels (75%), localised cutaneous form (20%), disseminated cutaneous and extracuteus rarely. The systemic disseminated sporotrichosis is considered a severe opportunistic infection. The best diagnostic test is the culture. The authors report a case of a 36-year-old man, originally from Puebla, Mexico, with a diagnosis of disseminated sporotrichosis. Differential diagnosis with other pathologies includes leishmaniasis, chromoblastomycosis, tuberculosis verrucose and lymphangitis. The development of unusual presentations in immunocompromised patients has been reported.

  17. Disseminated sporotrichosis

    PubMed Central

    Romero-Cabello, Raúl; Bonifaz, Alexandro; Romero-Feregrino, Raúl; Sánchez, Carlos Javier; Linares, Yancy; Zavala, Jorge Tay; Romero, Leticia Calderón; Romero-Feregrino, Rodrigo; Vega, José T Sánchez

    2011-01-01

    Sporotrichosis is a subacute or chronic infection caused by Sporothrix schenckii. It is a primary cutaneous infection and it has different clinical forms: disseminated by lymphatic vessels (75%), localised cutaneous form (20%), disseminated cutaneous and extracuteus rarely. The systemic disseminated sporotrichosis is considered a severe opportunistic infection. The best diagnostic test is the culture. The authors report a case of a 36-year-old man, originally from Puebla, Mexico, with a diagnosis of disseminated sporotrichosis. Differential diagnosis with other pathologies includes leishmaniasis, chromoblastomycosis, tuberculosis verrucose and lymphangitis. The development of unusual presentations in immunocompromised patients has been reported. PMID:22700076

  18. Smithsonian-Peace Corps Environmental Program: A Progress Report

    ERIC Educational Resources Information Center

    Peter, Walter G., III

    1974-01-01

    Evaluates progress made by the Smithsonian - Peace Corps Environmental Program in which biologists are recruited to initiate and administer research projects dealing with environmental problems in developing nations. (JR)

  19. F-35 Joint Strike Fighter: Observations on Program Progress

    DTIC Science & Technology

    2015-04-14

    F - 35 JOINT STRIKE FIGHTER Observations on Program Progress Statement of Michael J. Sullivan, Director Acquisition...2. REPORT TYPE 3. DATES COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE F - 35 Joint Strike Fighter: Observations on Program Progress 5a...15-429T Chairman Turner, Ranking Member Sanchez, and Members of the Subcommittee: Thank you for the opportunity to discuss our work on the F - 35

  20. Evaluation of a data dictionary system. [information dissemination and computer systems programs

    NASA Technical Reports Server (NTRS)

    Driggers, W. G.

    1975-01-01

    The usefulness was investigated of a data dictionary/directory system for achieving optimum benefits from existing and planned investments in computer data files in the Data Systems Development Branch and the Institutional Data Systems Division. Potential applications of the data catalogue system are discussed along with an evaluation of the system. Other topics discussed include data description, data structure, programming aids, programming languages, program networks, and test data.

  1. Clinical Investigation Program Annual Progress Report

    DTIC Science & Technology

    1989-09-30

    pre-op obstructive side, and is this subjectively noted by the patient to the point of causing secondary obstructive symptoms , of any degree on the...Lipolytic Enzymes in Sedentary, Healthy Men ................. 109 87/110A C The Role of Excess Prostaglandin Production in Causing the Abnormal...Duration of Symptoms Important? ... 154 89/105 0 Role of Blood Pressure Control in Progression of Diabetic Nephropathy and Other Microangiopathies .155 89

  2. Improved Physical Fitness among Older Female Participants in a Nationally Disseminated, Community-Based Exercise Program

    ERIC Educational Resources Information Center

    Seguin, Rebecca A.; Heidkamp-Young, Eleanor; Kuder, Julia; Nelson, Miriam E.

    2012-01-01

    Background: Strength training (ST) is an important health behavior for aging women; it helps maintain strength and function and reduces risk for chronic diseases. This study assessed change in physical fitness following participation in a ST program implemented and evaluated by community leaders. Method: The StrongWomen Program is a nationally…

  3. Improved Physical Fitness among Older Female Participants in a Nationally Disseminated, Community-Based Exercise Program

    ERIC Educational Resources Information Center

    Seguin, Rebecca A.; Heidkamp-Young, Eleanor; Kuder, Julia; Nelson, Miriam E.

    2012-01-01

    Background: Strength training (ST) is an important health behavior for aging women; it helps maintain strength and function and reduces risk for chronic diseases. This study assessed change in physical fitness following participation in a ST program implemented and evaluated by community leaders. Method: The StrongWomen Program is a nationally…

  4. TIM, a ray-tracing program for METATOY research and its dissemination

    NASA Astrophysics Data System (ADS)

    Lambert, Dean; Hamilton, Alasdair C.; Constable, George; Snehanshu, Harsh; Talati, Sharvil; Courtial, Johannes

    2012-03-01

    TIM (The Interactive METATOY) is a ray-tracing program specifically tailored towards our research in METATOYs, which are optical components that appear to be able to create wave-optically forbidden light-ray fields. For this reason, TIM possesses features not found in other ray-tracing programs. TIM can either be used interactively or by modifying the openly available source code; in both cases, it can easily be run as an applet embedded in a web page. Here we describe the basic structure of TIM's source code and how to extend it, and we give examples of how we have used TIM in our own research. Program summaryProgram title: TIM Catalogue identifier: AEKY_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEKY_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License No. of lines in distributed program, including test data, etc.: 124 478 No. of bytes in distributed program, including test data, etc.: 4 120 052 Distribution format: tar.gz Programming language: Java Computer: Any computer capable of running the Java Virtual Machine (JVM) 1.6 Operating system: Any; developed under Mac OS X Version 10.6 RAM: Typically 145 MB (interactive version running under Mac OS X Version 10.6) Classification: 14, 18 External routines: JAMA [1] (source code included) Nature of problem: Visualisation of scenes that include scene objects that create wave-optically forbidden light-ray fields. Solution method: Ray tracing. Unusual features: Specifically designed to visualise wave-optically forbidden light-ray fields; can visualise ray trajectories; can visualise geometric optic transformations; can create anaglyphs (for viewing with coloured "3D glasses") and random-dot autostereograms of the scene; integrable into web pages. Running time: Problem-dependent; typically seconds for a simple scene.

  5. Clearwater Focus Program, 2003 Progress Report.

    SciTech Connect

    Hohle, Janet

    2003-12-01

    The Clearwater River sub-basin was designated a coordination program under the 1994 Columbia River Basin Fish and Wildlife Program by the Northwest Power and Conservation Council (Council) in November 1996. The Clearwater Focus Program is co-coordinated by Idaho State and the Nez Perce Tribe, this Bonneville funded contract is sponsored by the Idaho Soil Conservation Commission (ISCC) on behalf of Idaho State. The contract term for this program has been synchronized with the state fiscal year, which is from July 1 to June 30, to facilitate contract administration and accounting. This report presents a narrative summary of work conducted from January 1, 2003 to December 31, 2003 during which the Clearwater Sub-basin Plan was revised for final submission to the Council to be considered as an amendment to the 2000 Fish and Wildlife Program. Activities described in this report took place over parts of two different contract periods. Reporting of tasks and objectives specific to each contract can be found in quarterly reports that have been submitted to the Bonneville project manager.

  6. 2015 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    SciTech Connect

    Popovich, Neil

    2015-12-01

    In the past year, the DOE Hydrogen Program (the Program) made substantial progress toward its goals and objectives. The Program has conducted comprehensive and focused efforts to enable the widespread commercialization of hydrogen and fuel cell technologies in diverse sectors of the economy. With emphasis on applications that will effectively strengthen our nation's energy security and improve our stewardship of the environment, the Program engages in research, development, and demonstration of critical improvements in the technologies. Highlights of the Program's accomplishments can be found in the sub-program chapters of this report.

  7. 2012 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    SciTech Connect

    Not Available

    2012-12-01

    In the past year, the DOE Hydrogen Program (the Program) made substantial progress toward its goals and objectives. The Program has conducted comprehensive and focused efforts to enable the widespread commercialization of hydrogen and fuel cell technologies in diverse sectors of the economy. With emphasis on applications that will effectively strengthen our nation's energy security and improve our stewardship of the environment, the Program engages in research, development, and demonstration of critical improvements in the technologies. Highlights of the Program's accomplishments can be found in the sub-program chapters of this report.

  8. Partnerships for Progress: Summer Youth Nutrition Programs.

    ERIC Educational Resources Information Center

    Guion, Lisa A.

    1998-01-01

    The North Carolina Cooperative Extension Service implemented summer youth nutrition to provide youth with information on the fundamentals of proper nutrition and contribute to their personal development and overall well-being. Collaboration among extension professionals and with external partners enabled the program to serve a total of 1469 youth.…

  9. Better Buildings Neighborhood Program Progress Stories

    SciTech Connect

    2012-04-19

    n neighborhoods across the country, stories are emerging constantly of individuals, businesses, and organizations that are benefiting from energy efficiency. Included are the stories of real people making their homes, businesses, and communities better with the help of the Better Buildings Neighborhood Program.

  10. The Canadian Tissue Repository Network Biobank Certification and the College of American Pathologists Biorepository Accreditation Programs: Two Strategies for Knowledge Dissemination in Biobanking.

    PubMed

    Barnes, Rebecca O; Shea, Katheryn E; Watson, Peter H

    2017-02-01

    As health research increasingly relies on biospecimens and associated data, new demands have emerged for biorepositories to provide assurances of the quality of their overall operations, not just assurances of the quality of the biospecimens and data that they hold. The biobanking community has responded in various ways, including the creation of two different programs to disseminate biobanking best practices. This article describes in detail the Canadian Tissue Repository Network (CTRNet) Biobank Certification Program and the College of American Pathologists (CAP) Biorepository Accreditation Program. Despite differences in their approaches, these programs share one key element-assessment of biobanking practices by an external organization. In the absence of a single internationally endorsed biobanking best practices dissemination program, the CTRNet and CAP programs provide two different solutions, each contributing to the pursuit of enhanced quality in biobanking.

  11. Validity of a web-based educational program to disseminate a standardized bowel preparation rating scale

    PubMed Central

    Calderwood, Audrey H.; Logan, Judith R.; Zurfluh, Michael; Lieberman, David A.; Jacobson, Brian C.; Heeren, Timothy C.; Schroy, Paul C.

    2013-01-01

    Goals Our goal was to assess the validity of a web-based educational program on the Boston Bowel Preparation Scale (BBPS). Background Data on web-based education for improving the practice and quality of colonoscopy are limited. Study Endoscopists worldwide participated in the BBPS Educational Program. We assessed program completion rates, satisfaction, short- (0–90 days) and long-term (91–180 days) uptake of the BBPS, and the validity of the program by measuring the reliability of the BBPS among participants. Results Two hundred seven endoscopists completed the program. Overall, 93% found the content relevant, 89% felt confident in using the BBPS, and 97% thought the quality was good or excellent. Uptake of the BBPS into clinical practice was robust with 91% and 98% of colonoscopy reports containing the BBPS at short- and long-term follow-up. The interobserver and test-retest reliability of BBPS segment and total scores were both substantial. Conclusions A BBPS web-based educational program facilitates adoption into clinical practice and teaches the BBPS to be used reliably by a diverse group of endoscopists worldwide. PMID:24463841

  12. Validity of a Web-based educational program to disseminate a standardized bowel preparation rating scale.

    PubMed

    Calderwood, Audrey H; Logan, Judith R; Zurfluh, Michael; Lieberman, David A; Jacobson, Brian C; Heeren, Timothy C; Schroy, Paul C

    2014-01-01

    Our goal was to assess the validity of a Web-based educational program on the Boston Bowel Preparation Scale (BBPS). Data on Web-based education for improving the practice and quality of colonoscopy are limited. Endoscopists worldwide participated in the BBPS Educational Program. We assessed program completion rates, satisfaction, short-term (0 to 90 d) and long-term (91 to 180 d) uptake of the BBPS, and the validity of the program by measuring the reliability of the BBPS among participants. A total of 207 endoscopists completed the program. Overall, 93% found the content relevant, 89% felt confident in using the BBPS, and 97% thought the quality was good or excellent. Uptake of the BBPS into clinical practice was robust with 91% and 98% of colonoscopy reports containing the BBPS at short-term and long-term follow-up, respectively. The interobserver and test-retest reliability of BBPS segment and total scores were both substantial. A BBPS Web-based educational program facilitates adoption into clinical practice and teaches the BBPS to be used reliably by a diverse group of endoscopists worldwide.

  13. 2013 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    SciTech Connect

    none,

    2013-12-01

    The 2013 Annual Progress Report summarizes fiscal year 2013 activities and accomplishments by projects funded by the DOE Hydrogen Program. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing; technology validation; safety, codes and standards; market transformation; and systems analysis.

  14. 2011 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    SciTech Connect

    Satyapal, Sunita

    2011-11-01

    The 2011 Annual Progress Report summarizes fiscal year 2011 activities and accomplishments by projects funded by the DOE Hydrogen Program. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing; technology validation; safety, codes and standards; education; market transformation; and systems analysis.

  15. 2014 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    SciTech Connect

    none,

    2014-11-01

    The 2014 Annual Progress Report summarizes fiscal year 2014 activities and accomplishments by projects funded by the DOE Hydrogen Program. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing; technology validation; safety, codes and standards; market transformation; and systems analysis.

  16. 2015 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    SciTech Connect

    None, None

    2015-12-23

    The 2015 Annual Progress Report summarizes fiscal year 2015 activities and accomplishments by projects funded by the DOE Hydrogen and Fuel Cells Program. It covers the program areas of hydrogen production; hydrogen delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes and standards; systems analysis; and market transformation.

  17. Assessment Program Technical Progress Report, 1996-1997.

    ERIC Educational Resources Information Center

    McCown, Laurie; Fanning, Erin; Eickmeyer, Barbara

    Coconino Community College (CCC) annually assesses its institutional effectiveness to demonstrate its commitment to improving programs and services to students. The 1996-97 Assessment Program Technical Progress Report records the assessment and institutional activities enacted during the academic year, detailing the assessment model, timelines,…

  18. Indiana Statewide Testing for Educational Progress--ISTEP--Program Manual.

    ERIC Educational Resources Information Center

    Indiana State Dept. of Education, Indianapolis.

    To assist administrators, teachers, and other school personnel in understanding and implementing the various components of the Indiana Statewide Testing for Educational Progress (ISTEP) program, this manual details the ISTEP program, a broad-based achievement testing plan providing Indiana schools with a means of assessing their overall…

  19. Acute onset and rapid progression of multiple organ failure in a young adult with undiagnosed disseminated colonic adenocarcinoma.

    PubMed

    Frestad, Daria; Perner, Anders; Pedersen, Ulf Gøttrup

    2014-09-24

    Colourectal cancer (CRC) is the fourth most common cause of death from cancer worldwide. While rates for CRC in adults age 50 and older have been declining, incidence rates in young adults, a population routinely not screened, has been increasing. We report a rare case of high-grade CRC in a previously healthy 27-year-old man, presented to us with symptoms of increasing abdominal pain and distension. Extensive diagnostic investigation revealed hepatomegaly with multiple processes, signs of vasculitis, extensive liver necrosis, enlarged retroperitoneal and mesenteric lymph nodes, splenomegaly, ascites and multiple vein thrombosis. The patient passed away shortly after admission due to treatment-resistant tumour lysis syndrome and multiple organ failure. Biopsy results revealed disseminated adenocarcinoma of the colon, with metastases to lymph nodes, liver, lungs and pleura. CRC in younger patients tend to present at a later stage and appears to be more aggressive, with a poorer pathological differentiation. 2014 BMJ Publishing Group Ltd.

  20. Constance mirror program: Progress and plans

    NASA Technical Reports Server (NTRS)

    Klinkowstein, R. E.; Mauel, M. E.; Irby, J. H.; Smullin, L. D.; Voldman, S. H.

    1981-01-01

    The current state of the mechanics of the Constance II experiment, the physics results gathered, the motivation background, and future plans for the Constance II experiment are reviewed. Several improvements have been made and several experimental investigations have been completed. These include the construction/installation/testing of: (1) liquid-nitrogen cooled, Ioffe bars installed, (2) a diverter coil (3) the 100 kW ICRF generator, (4) the data acquisition system, and (5) the optimum hot-iron operation of the machine with Titanium and pulsed-gas plasma guns. Measurements were made of the density, temperature, and radius of the plasma. Ion-cyclotron fluctuations were observed, their bandwidth measured, and data collected demonstrating resonance heating. New X-ray diagnostics were designed and purchased, and progress on the Thomson scattering was made. Finally, a new hot cathode gun was designed and constructed.

  1. Programmatic Research to Develop and Disseminate Improved Instructional Technology for Handicapped Children. Project MORE Quarterly Progress Report, September 1 to December 1, 1972.

    ERIC Educational Resources Information Center

    Schiefelbusch, Richard L.; Lent, James R.

    During the past reporting period the curriculum development staff of Project MORE (Mediated Operational Research for Education) has made substantial progress in attaining its program objectives. Design and development phases have proceeded on schedule. Four programs are currently in the field-testing stage, and four others are under development.…

  2. Disseminating Incredible Years Series Early-Intervention Programs: Integrating and Sustaining Services between School and Home

    ERIC Educational Resources Information Center

    Webster-Stratton, Carolyn; Herman, Keith C.

    2010-01-01

    The Incredible Years (IY) Series is a well-established set of parent, teacher, and child programs for treating and preventing conduct problems and promoting social competence and emotional regulation in young children. The purpose of this article is to describe the development of this evidence-based series within the context of a prevention…

  3. Disseminating ASD Interventions: A Pilot Study of a Distance Learning Program for Parents and Professionals

    ERIC Educational Resources Information Center

    Wainer, Allison L.; Ingersoll, Brooke R.

    2013-01-01

    There is a need for the adaptation of training in evidence-based interventions to non-traditional methods, particularly for individuals working with children with autism spectrum disorders (ASD). An internet-based self-directed distance learning program was created to teach reciprocal imitation training, a naturalistic behavioral intervention…

  4. The SPARK Programs: A Public Health Model of Physical Education Research and Dissemination

    ERIC Educational Resources Information Center

    McKenzie, Thomas L.; Sallis, James F.; Rosengard, Paul; Ballard, Kymm

    2016-01-01

    SPARK [Sports, Play, and Active Recreation for Kids], in its current form, is a brand that represents a collection of exemplary, research-based, physical education and physical activity programs that emphasize a highly active curriculum, on-site staff development, and follow-up support. Given its complexity (e.g., multiple school levels, inclusion…

  5. Comparison of Programs Used for FIA Inventory Information Dissemination and Spatial Representation

    Treesearch

    Roger C. Lowe; Chris J. Cieszewski

    2005-01-01

    Six online applications developed for the interactive display of Forest Inventory and Analysis (FIA) data in which FIA database information and query results can be viewed as or selected from interactive geographic maps are compared. The programs evaluated are the U.S. Department of Agriculture Forest Service?s online systems; a SAS server-based mapping system...

  6. The SPARK Programs: A Public Health Model of Physical Education Research and Dissemination

    ERIC Educational Resources Information Center

    McKenzie, Thomas L.; Sallis, James F.; Rosengard, Paul; Ballard, Kymm

    2016-01-01

    SPARK [Sports, Play, and Active Recreation for Kids], in its current form, is a brand that represents a collection of exemplary, research-based, physical education and physical activity programs that emphasize a highly active curriculum, on-site staff development, and follow-up support. Given its complexity (e.g., multiple school levels, inclusion…

  7. Disseminating ASD Interventions: A Pilot Study of a Distance Learning Program for Parents and Professionals

    ERIC Educational Resources Information Center

    Wainer, Allison L.; Ingersoll, Brooke R.

    2013-01-01

    There is a need for the adaptation of training in evidence-based interventions to non-traditional methods, particularly for individuals working with children with autism spectrum disorders (ASD). An internet-based self-directed distance learning program was created to teach reciprocal imitation training, a naturalistic behavioral intervention…

  8. Dissemination of a Child Passenger Safety Program Through Trauma Center-Community Partnerships.

    PubMed

    Adams, Christy M; Morris, Catherine E; Salcedo, Edgardo S; Holmes, James F

    Improper child passenger restraint use contributes to higher pediatric motor vehicle collision morbidity and mortality among cultural minority populations. Child passenger safety education improves caregiver knowledge of restraint use, but effective interventions require culturally specific programming. The purpose of this study was to evaluate the effectiveness of a child passenger safety education program culturally adapted through a pediatric trauma center's community partnerships. A nonexperimental observational cohort study using program evaluation data for the child passenger safety education programs during a 24-month period. Paired pretest/posttest self-reported survey responses measured changes in caregiver knowledge and self-efficacy of restraint use. Data were analyzed by class location and by caregiver language using a paired t test and Wilcoxon's signed ranks test. A total of 1,795 paired survey responses were collected in English, Spanish, or Russian. An increase in mean knowledge scores occurred overall, with a difference in mean of 0.565 (SE = 0.022, 95% CI [0.521, 0.607]). Stratification by class site and by language reflected significant increases in median scores, but findings were variable by study group. Pretest median scores for self-efficacy of restraint use were high for all groups, but the increases in posttest medians were also significant across groups (p ≤ .001). Caregiver knowledge and self-efficacy for child passenger restraint use increased after participation in the community classes. The pediatric trauma center's community partnerships facilitated uptake and adaption of the child passenger safety education programs and increased the injury prevention outreach to minority communities.

  9. Dissemination of Chronic Disease Self-Management Education (CDSME) Programs in the United States: Intervention Delivery by Rurality

    PubMed Central

    Smith, Matthew Lee; Towne, Samuel D.; Herrera-Venson, Angelica; Cameron, Kathleen; Kulinski, Kristie P.; Lorig, Kate; Horel, Scott A.; Ory, Marcia G.

    2017-01-01

    Background: Alongside the dramatic increase of older adults in the United States (U.S.), it is projected that the aging population residing in rural areas will continue to grow. As the prevalence of chronic diseases and multiple chronic conditions among adults continues to rise, there is additional need for evidence-based interventions to assist the aging population to improve lifestyle behaviors, and self-manage their chronic conditions. The purpose of this descriptive study was to identify the geospatial dissemination of Chronic Disease Self-Management Education (CDSME) Programs across the U.S. in terms of participants enrolled, workshops delivered, and counties reached. These dissemination characteristics were compared across rurality designations (i.e., metro areas; non-metro areas adjacent to metro areas, and non-metro areas not adjacent to metro areas). Methods: This descriptive study analyzed data from a national repository including efforts from 83 grantees spanning 47 states from December 2009 to December 2016. Counts were tabulated and averages were calculated. Results: CDSME Program workshops were delivered in 56.4% of all U.S. counties one or more times during the study period. Of the counties where a workshop was conducted, 50.5% were delivered in non-metro areas. Of the 300,640 participants enrolled in CDSME Programs, 12% attended workshops in non-metro adjacent areas, and 7% attended workshops in non-metro non-adjacent areas. The majority of workshops were delivered in healthcare organizations, senior centers/Area Agencies on Aging, and residential facilities. On average, participants residing in non-metro areas had better workshop attendance and retention rates compared to participants in metro areas. Conclusions: Findings highlight the established role of traditional organizations/entities within the aging services network, to reach remote areas and serve diverse participants (e.g., senior centers). To facilitate growth in rural areas, technical

  10. Office of Special Education Programs' Annual Technical Assistance and Dissemination Conference Proceedings (4th, Washington, D.C., January 27-29, 1994).

    ERIC Educational Resources Information Center

    Academy for Educational Development, Washington, DC.

    This document presents the proceedings of a conference attended by Project Directors (or their designees) of projects funded by the Office of Special Education Programs (OSEP) and having a significant component of technical assistance (TA) and/or dissemination activities. The conference was designed to provide new information to projects, to…

  11. The Use of Educational Knowledge; Evaluation of the Pilot State Dissemination Program. Volume II: Part VIII, Case Studies of Field Agents in Action. Final Report.

    ERIC Educational Resources Information Center

    Sieber, Sam D.; And Others

    This volume, a continuation of Volume I, presents Part VIII of the report and 12 appendixes. Part VIII is comprised of case studies of the activities of field agents in three states that are the target areas of the Pilot State Dissemination Program. The areas are designated "Southern Small Town,""The Hazelton Districts," and…

  12. National dissemination of StrongWomen – Healthy Hearts: A community-based program to reduce risk of cardiovascular disease among midlife and older women

    USDA-ARS?s Scientific Manuscript database

    Objective: We describe the national dissemination of an evidence-based community cardiovascular disease prevention program for midlife and older women using the RE-AIM (reach effectiveness adoption implementation maintenance) framework and share key lessons learned during translation. Methods: In a ...

  13. [A case report of two-term surgery for focal progression of a huge liver metastasis and peritoneal dissemination from gastrointestinal stromal tumor during imatinib mesylate treatment].

    PubMed

    Toyokawa, Takahiro; Teraoka, Hitoshi; Kitayama, Kisyu; Nomura, Shinya; Kanehara, Isao; Nishino, Hiroji

    2014-03-01

    We report a patient who underwent 2-term surgery to treat focal progression of a huge liver metastasis and peritoneal dissemination from a gastric gastrointestinal stromal tumor(GIST)during imatinib mesylate treatment. A 59-year-old man underwent an emergency surgery for perforative peritonitis caused by gastric GIST in June 2006 and a partial resection of the stomach in September 2006. Four years later, abdominal computed tomography(CT)detected a huge liver tumor that occupied the entire right lobe. We initiated imatinib mesylate treatment(400mg/day), and the patient maintained stable disease for several months. However, focal progression of the huge liver tumor and a peritoneal tumor at the splenic hilum were revealed by CT; therefore, an extended right hepatic resection was performed in August 2011 and a distal pancreatectomy, splenectomy, and partial resection of the stomach were performed in February 2012. The patient died of the primary disease at 16 months after the hepatic resection for focal progression.

  14. Exploring facilitating factors and barriers to the nationwide dissemination of a Dutch school-based obesity prevention program “DOiT”: a study protocol

    PubMed Central

    2013-01-01

    Background The evidence-based Dutch Obesity Intervention in Teenagers (DOiT) program is a school-based obesity prevention program for 12 to 14-year olds attending the first two years of prevocational education. This paper describes the study protocol applied to evaluate (a) the nationwide dissemination process of DOiT in the Netherlands, and (b) the relationship between quality of implementation and effectiveness during nationwide dissemination of the program in the Netherlands. Methods In order to explore facilitating factors and barriers for dissemination of DOiT, we monitored the process of adoption, implementation and continuation of the DOiT program among 20 prevocational schools in the Netherlands. The study was an observational study using qualitative (i.e. semi-structured interviews) and quantitative methods (i.e. questionnaires and logbooks). Eight process indicators were assessed: recruitment, context, reach, dosage, fidelity, satisfaction, effectiveness and continuation. All teachers, students and parents involved in the implementation of the program were invited to participate in the study. As part of the process evaluation, a cluster-controlled trial with ten control schools was conducted to evaluate the effectiveness of the program on students’ anthropometry and energy balance-related behaviours and its association with quality of implementation. Discussion The identified impeding and facilitating factors will contribute to an adjusted strategy promoting adoption, implementation and continuation of the DOiT program to ensure optimal use and, thereby, prevention of obesity in Dutch adolescents. Trial registration Current Controlled Trials ISRCTN92755979. PMID:24355056

  15. Pressure vessel burst test program - Progress paper No. 3

    NASA Technical Reports Server (NTRS)

    Cain, Maurice R.; Sharp, Douglas E.; Coleman, Michael D.

    1992-01-01

    An updated progress report is provided on a program developed to study through test and analysis, the characteristics of blast waves and fragmentation generated by ruptured gas filled pressure vessels. Prior papers on this USAF/NASA/General Physics program were presented to the AIAA in July 1990 and June 1991. Ten pressure vessels have been burst using pneumatic pressure. Tests were designed to explore burst characteristics and used an instrumented arena. Data trends for current experiments are presented. This paper is the third progress report on the program and addresses: (1) a brief review of current methods for assessing vessel safety and burst parameters, (2) a review of pneumatic burst testing operations and testing results, including a comparison to current methods for burst assessment, and (3) a review of the basis for the current test program including planned testing.

  16. [Progress in synthetic biology of "973 Funding Program" in China].

    PubMed

    Chen, Guoqiang; Wang, Ying

    2015-06-01

    This paper reviews progresses made in China from 2011 in areas of "Synthetic Biology" supported by State Basic Research 973 Program. Till the end of 2014, 9 "synthetic biology" projects have been initiated with emphasis on "microbial manufactures" with the 973 Funding Program. Combined with the very recent launch of one project on "mammalian cell synthetic biology" and another on "plant synthetic biology", Chinese "synthetic biology" research reflects its focus on "manufactures" while not giving up efforts on "synthetic biology" of complex systems.

  17. Enhanced surveillance program FY97 accomplishments. Progress report

    SciTech Connect

    Mauzy, A.; Laake, B.

    1997-10-01

    This annual report is one volume of the Enhanced Surveillance Program (ESP) FY97 Accomplishments. The complete accomplishments report consists of 11 volumes. Volume 1 includes an ESP overview and a summary of selected unclassified FY97 program highlights. Volume 1 specifically targets a general audience, reflecting about half of the tasks conducted in FY97 and emphasizing key program accomplishments and contributions. The remaining volumes of the accomplishments report are classified, organized by program focus area, and present in technical detail the progress achieved in each of the 104 FY97 program tasks. Focus areas are as follows: pits; high explosives; organics; dynamics; diagnostics; systems; secondaries; nonnuclear materials; nonnuclear components; and Surveillance Test Program upgrades.

  18. Advanced research and technology development fossil energy materials program. Quarterly progress report for the period ending September 30, 1981

    SciTech Connect

    Bradley, R.A.

    1981-12-01

    This is the fourth combined quarterly progress report for those projects that are part of the Advanced Research and Technology Development Fossil Energy Materials Program. The objective is to conduct a program of research and development on materials for fossil energy applications with a focus on the longer-term and generic needs of the various fossil fuel technologies. The program includes research aimed toward a better understanding of materials behavior in fossil energy environments and the development of new materials capable of substantial enhancement of plant operations and reliability. Work performed on the program generally falls into the Applied Research and Exploratory Development categories as defined in the DOE Technology Base Review, although basic research and engineering development are also conducted. A substantial portion of the work on the AR and TD Fossil Energy Materials Program is performed by participating cntractor organizations. All subcontractor work is monitored by Program staff members at ORNL and Argonne National Laboratory. This report is organized in accordance with a work breakdown structure defined in the AR and TD Fossil Energy Materials Program Plan for FY 1981 in which projects are organized according to fossil energy technologies. We hope this series of AR and TD Fossil Energy Materials Program quarterly progress reports will aid in the dissemination of information developed on the program.

  19. Integral Fast Reactor Program. Annual progress report, FY 1993

    SciTech Connect

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

    1994-10-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1993. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R and D.

  20. DOE Hydrogen and Fuel Cells Program Annual Progress Report

    SciTech Connect

    2012-04-11

    These progress reports summarize the year's hydrogen and fuel cell R&D and analysis activities and accomplishments. This work was conducted by industry, academia, and national laboratories for the DOE Hydrogen and Fuel Cells Program and the offices of Energy Efficiency and Renewable Energy (EERE), Fossil Energy, Nuclear Energy, and Science.

  1. Assessment Program Technical Progress Report, 1997-1998.

    ERIC Educational Resources Information Center

    Eickmeyer, Barbara; Hill, Stephen

    This Assessment Program Progress Report (APPR) records the institutional activities that have taken place at Coconino Community College (CCC) during the 1997-98 academic year. It presents models, timelines, accomplishments, and opportunities for improvement in the assessment practices at CCC. Implementation and outcomes information is included for…

  2. Integral Fast Reactor Program annual progress report, FY 1991

    SciTech Connect

    Not Available

    1992-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1991. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R&D.

  3. Integral Fast Reactor Program annual progress report, FY 1991

    SciTech Connect

    Not Available

    1992-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1991. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R D.

  4. Integral Fast Reactor Program annual progress report, FY 1994

    SciTech Connect

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, J.J.

    1994-12-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1994. Technical accomplishments are presented in the following areas of the IFR technology development activities: metal fuel performance; pyroprocess development; safety experiments and analyses; core design development; fuel cycle demonstration; and LMR technology R&D.

  5. Integral Fast Reactor Program. Annual progress report, FY 1992

    SciTech Connect

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

    1993-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1992. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R&D.

  6. A large-scale initiative to disseminate an evidence-based drug abuse prevention program in Italy: Lessons learned for practitioners and researchers.

    PubMed

    Velasco, Veronica; Griffin, Kenneth W; Antichi, Mariella; Celata, Corrado

    2015-10-01

    Across developed countries, experimentation with alcohol, tobacco, and other drugs often begins in the early adolescent years. Several evidence-based programs have been developed to prevent adolescent substance use. Many of the most rigorously tested and empirically supported prevention programs were initially developed and tested in the United States. Increasingly, these interventions are being adopted for use in Europe and throughout the world. This paper reports on a large-scale comprehensive initiative designed to select, adapt, implement, and sustain an evidence-based drug abuse prevention program in Italy. As part of a large-scale regionally funded collaboration in the Lombardy region of Italy, we report on processes through which a team of stakeholders selected, translated and culturally adapted, planned, implemented and evaluated the Life Skills Training (LST) school-based drug abuse prevention program, an evidence-based intervention developed in the United States. We discuss several challenges and lessons learned and implications for prevention practitioners and researchers attempting to undertake similar international dissemination projects. We review several published conceptual models designed to promote the replication and widespread dissemination of effective programs, and discuss their strengths and limitations in the context of planning and implementing a complex, large-scale real-world dissemination effort. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Healthy Living after Cancer: a dissemination and implementation study evaluating a telephone-delivered healthy lifestyle program for cancer survivors.

    PubMed

    Eakin, Elizabeth G; Hayes, Sandra C; Haas, Marion R; Reeves, Marina M; Vardy, Janette L; Boyle, Frances; Hiller, Janet E; Mishra, Gita D; Goode, Ana D; Jefford, Michael; Koczwara, Bogda; Saunders, Christobel M; Demark-Wahnefried, Wendy; Courneya, Kerry S; Schmitz, Kathryn H; Girgis, Afaf; White, Kate; Chapman, Kathy; Boltong, Anna G; Lane, Katherine; McKiernan, Sandy; Millar, Lesley; O'Brien, Lorna; Sharplin, Greg; Baldwin, Polly; Robson, Erin L

    2015-12-21

    Given evidence shows physical activity, a healthful diet and weight management can improve cancer outcomes and reduce chronic disease risk, the major cancer organisations and health authorities have endorsed related guidelines for cancer survivors. Despite these, and a growing evidence base on effective lifestyle interventions, there is limited uptake into survivorship care. Healthy Living after Cancer (HLaC) is a national dissemination and implementation study that will evaluate the integration of an evidence-based lifestyle intervention for cancer survivors into an existing telephone cancer information and support service delivered by Australian state-based Cancer Councils. Eligible participants (adults having completed cancer treatment with curative intent) will receive 12 health coaching calls over 6 months from Cancer Council nurses/allied health professionals targeting national guidelines for physical activity, healthy eating and weight control. Using the RE-AIM evaluation framework, primary outcomes are service-level indicators of program reach, adoption, implementation/costs and maintenance, with secondary (effectiveness) outcomes of patient-reported anthropometric, behavioural and psychosocial variables collected at pre- and post-program completion. The total participant accrual target across four participating Cancer Councils is 900 over 3 years. The national scope of the project and broad inclusion of cancer survivors, alongside evaluation of service-level indicators, associated costs and patient-reported outcomes, will provide the necessary practice-based evidence needed to inform future allocation of resources to support healthy living among cancer survivors. Australian and New Zealand Clinical Trials Registry (ANZCTR)--ACTRN12615000882527 (registered on 24/08/2015).

  8. Progress in The Lost Circulation Technology Development Program

    SciTech Connect

    Glowka, D.A.; Schafer, D.M.; Loeppke, G.E.; Wright, E.K.

    1991-01-01

    Lost circulation is the loss of drilling fluid from the wellbore to fractures or pores in the rock formation. In geothermal drilling, lost circulation is often a serious problem that contributes greatly to the cost of the average geothermal well. The Lost Circulation Technology Development Program is sponsored at Sandia National Laboratories by the US Department of Energy. The goal of the program is to reduce lost circulation costs by 30--50{percent} through the development of mitigation and characterization technology. This paper describes the technical progress made in this program during the period April, 1990--March, 1991. 4 refs., 15 figs., 1 tab.

  9. Evaluation of the Progress and Challenges facing the Ponseti Method Program in Vietnam

    PubMed Central

    Wu, Vincent; Nguyen, Michelle; Nhi, Huynh Manh; Thanh, Do Van; Oprescu, Florin; Cook, Thomas; Morcuende, Jose A.

    2012-01-01

    Introduction In 2003, an ICRC-SFD Ponseti program was introduced in southern Vietnam. Additional programs were introduced by the Prosthetics Outreach Foundation and independently by physicians trained at our center. The purpose of this study was to evaluate the impact, progress and challenges facing Ponseti practitioners and patients' family members in Vietnam. In addition, web-conferencing (Ponseti Virtual Forum) for continued medical education in the method was also assessed. Methods Multiple questionnaires were developed to conduct face-to-face practitioner interviews, focus group interviews, and parental interviews. Observation was done at multiple site clinics to determine or confirm additional challenges faced by practitioners. Web conferencing was introduced to sites in Ho Chi Minh City and Da Nang City. Results The number of clubfoot patients treated with the Ponseti method has increased over time with approximately 1,252 infants treated between 2003 and 2010. Specific challenges were identified relating to communication, networking, distance and transportation, and finances for both practitioners and parents. The PVF was not only found to facilitate rapid, relevant dissemination of medical knowledge – thus increasing physician and patient satisfaction – but it may also be found to act as an interface in which medical culture, insight, and compassion are shared benefiting all virtual forum participants. Conclusion The identified progress and challenges mirrored that of similar studies done in other countries with several factors affecting progress. Focusing on improving communication channels and networking while working with the ministry of health may improve the facilitation of the Ponseti method in Vietnam. Further implementation and evaluation of the PVF may act as a guide for current and future programs in Vietnam or other countries. PMID:23576933

  10. The U.S. RERTR program status and progress.

    SciTech Connect

    Travelli, A.

    1998-01-21

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program since its inception in 1978 is described. A brief summary of the results which the RERTR Program had achieved by the end of 1996 in collaboration with its many international partners is followed by a detailed review of the major events, findings, and activities of 1997. Significant progress has been made during the past year. In the area of U.S. acceptance of spent fuel from foreign research reactors, several shipments have taken place and additional are being planned. Intense fuel development activities are in progress, including procurement of equipment, screening of candidate materials, and production of microplates. Irradiation of the first series of microplates began in August 1997 in the Advanced Test Reactor, in Idaho. Progress has been made in the Russian RERTR program, which aims to develop and demonstrate within five years the technical means needed to convert Russian-supplied research reactors to LEU fuels. The study of an alternative LEU core for the FRM-II design has been extended to address, with favorable results, controversial performance issues which were raised at last year's meeting. Progress was also made on several aspects of producing molybdenum-99 from fission targets utilizing LEU instead of HEU. Various types of targets and processes are being pursued, with FDA approval of an LEU process projected to occur within two years. The feasibility of LEU Fuel conversion for three important DOE research reactors (BMRR, HFBR, and HFIR) has been evaluated by the RERTR program. In spite of the many momentous events which have occurred during the intervening years, and the excellent progress achieved, the most important challenges that the RERTR program faces today are not very different in type from those that were faced during the first RERTR meeting. Now, as then, the most important task is to develop new LEU fuels satisfying requirements which cannot be satisfied by any

  11. The Progressive Insurance Automotive X PRIZE Education Program

    SciTech Connect

    Robyn Ready

    2011-12-31

    The Progressive Insurance Automotive X PRIZE Education Program conducted education and outreach activities and used the competition's technical goals and vehicle demonstrations as a means of attracting students and the public to learn more about advanced vehicle technologies, energy efficiency, climate change, alternative fuels, and the science and math behind efficient vehicle development. The Progressive Insurance Automotive X PRIZE Education Program comprised three integrated components that were designed to educate the general public and create a multi-tiered initiative to engage students and showcase the 21st century skills students will need to compete in our global economy: teamwork, creativity, strong literacy, math and science skills, and innovative thinking. The elements included an Online Experience, a National Student Contest, and in person education events and activites. The project leveraged online connections, strategic partnerships, in-classroom, and beyond-the-classroom initiatives, as well as mainstream media. This education program supported by the U.S. Department of Energy (DOE) also funded the specification of vehicle telemetry and the full development and operation of an interactive online experience that allowed internet users to follow the Progressive Insurance Automotive X PRIZE vehicles as they performed in real-time during the Progressive Insurance Automotive X PRIZE competition events.

  12. A Web-Disseminated Self-Help and Peer Support Program Could Fill Gaps in Mental Health Care: Lessons From a Consumer Survey.

    PubMed

    Bernecker, Samantha L; Banschback, Kaitlin; Santorelli, Gennarina D; Constantino, Michael J

    2017-01-19

    Self-guided mental health interventions that are disseminated via the Web have the potential to circumvent barriers to treatment and improve public mental health. However, self-guided interventions often fail to attract consumers and suffer from user nonadherence. Uptake of novel interventions could be improved by consulting consumers from the beginning of the development process in order to assess their interest and their preferences. Interventions can then be tailored using this feedback to optimize appeal. The aim of our study was to determine the level of public interest in a new mental health intervention that incorporates elements of self-help and peer counseling and that is disseminated via a Web-based training course; to identify predictors of interest in the program; and to identify consumer preferences for features of Web-based courses and peer support programs. We surveyed consumers via Amazon's Mechanical Turk to estimate interest in the self-help and peer support program. We assessed associations between demographic and clinical characteristics and interest in the program, and we obtained feedback on desired features of the program. Overall, 63.9% (378/592) of respondents said that they would try the program; interest was lower but still substantial among those who were not willing or able to access traditional mental health services. Female gender, lower income, and openness to using psychotherapy were the most consistent predictors of interest in the program. The majority of respondents, although not all, preferred romantic partners or close friends as peer counselors and would be most likely to access the program if the training course were accessed on a stand-alone website. In general, respondents valued training in active listening skills. In light of the apparent public interest in this program, Web-disseminated self-help and peer support interventions have enormous potential to fill gaps in mental health care. The results of this survey can be

  13. JC Polyomavirus Abundance and Distribution in Progressive Multifocal Leukoencephalopathy (PML) Brain Tissue Implicates Myelin Sheath in Intracerebral Dissemination of Infection

    PubMed Central

    Wharton, Keith A.; Quigley, Catherine; Themeles, Marian; Dunstan, Robert W.; Doyle, Kathryn; Cahir-McFarland, Ellen; Wei, Jing; Buko, Alex; Reid, Carl E.; Sun, Chao; Carmillo, Paul; Sur, Gargi; Carulli, John P.; Mansfield, Keith G.; Westmoreland, Susan V.; Staugaitis, Susan M.; Fox, Robert J.; Meier, Werner; Goelz, Susan E.

    2016-01-01

    Over half of adults are seropositive for JC polyomavirus (JCV), but rare individuals develop progressive multifocal leukoencephalopathy (PML), a demyelinating JCV infection of the central nervous system. Previously, PML was primarily seen in immunosuppressed patients with AIDS or certain cancers, but it has recently emerged as a drug safety issue through its association with diverse immunomodulatory therapies. To better understand the relationship between the JCV life cycle and PML pathology, we studied autopsy brain tissue from a 70-year-old psoriasis patient on the integrin alpha-L inhibitor efalizumab following a ~2 month clinical course of PML. Sequence analysis of lesional brain tissue identified PML-associated viral mutations in regulatory (non-coding control region) DNA, capsid protein VP1, and the regulatory agnoprotein, as well as 9 novel mutations in capsid protein VP2, indicating rampant viral evolution. Nine samples, including three gross PML lesions and normal-appearing adjacent tissues, were characterized by histopathology and subject to quantitative genomic, proteomic, and molecular localization analyses. We observed a striking correlation between the spatial extent of demyelination, axonal destruction, and dispersion of JCV along white matter myelin sheath. Our observations in this case, as well as in a case of PML-like disease in an immunocompromised rhesus macaque, suggest that long-range spread of polyomavirus and axonal destruction in PML might involve extracellular association between virus and the white matter myelin sheath. PMID:27191595

  14. Disseminating research.

    PubMed

    Baillie, Lesley

    2015-07-01

    THE THEME of this edition of Nurse Researcher, 'disseminating research', is pertinent to researchers across the career spectrum and tackles two important issues: open access publishing and originality in PhD research. In the first paper, Suzanne Fredericks examines and contrasts two models of open access publishing, revealing some notable advantages of 'green' open access, achieved through repositories, as opposed to the more well-known 'gold' open access offered by journals ( Fredericks 2015 ). In the second paper, Paul Gill and Gina Dolan discuss originality in PhD studies, exploring the nature of the concept and how doctoral students can demonstrate originality, which is an essential consideration in their research dissemination activities as well as their thesis preparation ( Gill and Dolan 2015 ).

  15. [DOE/EPSCoR traineeship program for Wyoming: Progress report

    SciTech Connect

    Not Available

    1992-08-01

    In the first year of the traineeship program supported by the Department of Energy EPSCoR funding, the University of Wyoming has made outstanding progress toward the objective of increasing the supply of highly trained engineers and scientists with interests in energy related disciplines. The scope of the traineeship program has already broadened to encompass both more departments than originally expected and nearly twice as many graduate students as expected. Further, since the primary emphasis was on new students, most of those recruited have developed ties to the DOE labs that would not have otherwise existed. This portion of this Progress Report gives an overall summary of the University of Wyoming`s approach to the DOE Traineeship Program implementation. It also provides an overview of the results so far and vision of how this program fits with the broader objectives for development of the University and its academic programs. Subsequent sections describe very briefly the impact of the traineeship students in each department that was successful in obtaining funds through the competitive process that was adopted. Finally, the report ends with a summary of both the academic status of the participants and the budget expenditures to date.

  16. (DOE/EPSCoR traineeship program for Wyoming: Progress report)

    SciTech Connect

    Not Available

    1992-01-01

    In the first year of the traineeship program supported by the Department of Energy EPSCoR funding, the University of Wyoming has made outstanding progress toward the objective of increasing the supply of highly trained engineers and scientists with interests in energy related disciplines. The scope of the traineeship program has already broadened to encompass both more departments than originally expected and nearly twice as many graduate students as expected. Further, since the primary emphasis was on new students, most of those recruited have developed ties to the DOE labs that would not have otherwise existed. This portion of this Progress Report gives an overall summary of the University of Wyoming's approach to the DOE Traineeship Program implementation. It also provides an overview of the results so far and vision of how this program fits with the broader objectives for development of the University and its academic programs. Subsequent sections describe very briefly the impact of the traineeship students in each department that was successful in obtaining funds through the competitive process that was adopted. Finally, the report ends with a summary of both the academic status of the participants and the budget expenditures to date.

  17. FY 2005 Annual Progress Report for the DOE Hydrogen Program

    SciTech Connect

    2005-10-01

    In cooperation with industry, academia, national laboratories, and other government agencies, the Department of Energy's Hydrogen Program is advancing the state of hydrogen and fuel cell technologies in support of the President's Hydrogen Fuel Initiative. The initiative seeks to develop hydrogen, fuel cell, and infrastructure technologies needed to make it practical and cost-effective for Americans to choose to use fuel cell vehicles by 2020. Significant progress was made in fiscal year 2005 toward that goal.

  18. The Family Development Research Program: A Program for Prenatal, Infant and Early Childhood Enrichment. Progress Report.

    ERIC Educational Resources Information Center

    Lally, J. Ronald

    This progress report on the Family Development Research Program for 108 low-income families, conducted at Syracuse University Children's Center, provides information on a longitudinal comparison instituted when the program children reached 36 months of age. The families of the children were matched to control families on a number of variables.…

  19. In preparation of the nationwide dissemination of the school-based obesity prevention program DOiT: stepwise development applying the intervention mapping protocol.

    PubMed

    van Nassau, Femke; Singh, Amika S; van Mechelen, Willem; Brug, Johannes; Chin A Paw, Mai J M

    2014-08-01

    The school-based Dutch Obesity Intervention in Teenagers (DOiT) program is an evidence-based obesity prevention program. In preparation for dissemination throughout the Netherlands, this study aimed to adapt the initial program and to develop an implementation strategy and materials. We revisited the Intervention Mapping (IM) protocol, using results of the previous process evaluation and additional focus groups and interviews with students, parents, teachers, and professionals. The adapted 2-year DOiT program consists of a classroom, an environmental and a parental component. The year 1 lessons aim to increase awareness and knowledge of healthy behaviors. The lessons in year 2 focus on the influence of the (obesogenic) environment. The stepwise development of the implementation strategy resulted in objectives that support teachers' implementation. We developed a 7-step implementation strategy and supporting materials by translating the objectives into essential elements and practical strategies. This study illustrates how revisiting the IM protocol resulted in an adapted program and tailored implementation strategy based on previous evaluations as well as input from different stakeholders. The stepwise development of DOiT can serve as an example for other evidence-based programs in preparation for wider dissemination. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

  20. Progress Report on Neglected Tropical Disease Drug Donation Programs.

    PubMed

    Cohen, Joshua P; Silva, Lisseth; Cohen, Alisa; Awatin, Josephine; Sturgeon, Robert

    2016-05-01

    Neglected tropical diseases (NTDs) impose a significant burden on public health, particularly in developing nations. Many can be treated cost-effectively with drugs donated or offered at or below marginal cost. In 2012, the World Health Organization published an NTD roadmap that outlined a strategy for the prevention, control, and eradication of 17 NTDs by 2020. Inspired by this roadmap, executives from 13 pharmaceutical companies, government agencies, and other interested parties signed the London Declaration on Neglected Tropical Diseases in January 2012. In this paper, we will assess progress in meeting commitments on drug donations laid out in the London Declaration. We conducted Medline and LexisNexis searches of peer-reviewed publications and trade journals, as well as product development partnership and government reports. Subsequently, we designed a survey instrument and surveyed 10 company signatories (companies with drug donation programs) to the London Declaration to determine current donations and pledges. Nine of 10 companies with donation programs responded to the survey. The respondents reported substantial progress in meeting the goals laid out in the London Declaration. Survey respondents maintained 17 drug donation programs across 10 disease categories. In 2014, companies donated >1 billion treatments, with a dollar value of nearly $1.5 billion. However, not all donated products were distributed to patients in need. In addition, 4 of the 17 programs were slated to end before 2020, three of the 17 programs did not report explicit program objectives, and 7 of 17 did not measure the impact of programs in terms of numbers of patients treated. None of our survey respondents reported on whether the programs were leading to a reduction in disease prevalence. Donations are a necessary but insufficient condition for patient access to neglected disease drugs. Additional resources must be allocated to ensure delivery of donated products to patients. In

  1. Fossil Energy Program semiannual progress report, October 1990--March 1991

    SciTech Connect

    Judkins, R.R.

    1992-07-01

    This report covers progress made during the period October 1, 1990, through March 31, 1991, for research and development projects that contribute to the advancement of various fossil energy technologies. Projects on the Fossil Energy Program are supported by the DOE Office of Fossil Energy, the DOE Morgantown Energy Technology Center, the DOE Pittsburgh Energy Technology Center, the DOE Fossil Energy Clean Coal Technology Program, the DOE Office of Basic Energy Sciences, the DOE Fossil Energy Office of Petroleum Reserves, the DOE Fossil Energy Naval Petroleum and Oil Shale Reserves, and the US Agency for International Development. The Fossil, Energy Program organization chart is shown in the appendix. Topics include: alloys, ceramics and composite research and development; corrosion and erosion research; environmental analysis and information systems; coal conversion development; mild gasification product characterization; coal combustion research; strategic petroleum reserve planning and modeling; and coal structure and chemistry.

  2. Electric and Hybrid Vehicle Program, Site Operator Program. Quarterly progress report, January--March 1996

    SciTech Connect

    Francfort, J.E.; Bassett, R.R.; Briasco, S.

    1996-08-01

    Goals of the site operator program include field evaluation of electric vehicles (EVs) in real-world applications and environments, advancement of electric vehicle technologies, development of infrastructure elements necessary to support significant EV use, and increasing the awareness and acceptance of EVs by the public. The site operator program currently consists of 11 participants under contract and two other organizations with data-sharing agreements with the program. The participants (electric utilities, academic institutions, Federal agencies) are geographically dispersed within US and their vehicles see a broad spectrum of service conditions. Current EV inventories of the site operators exceeds 250 vehicles. Several national organizations have joined DOE to further the introduction and awareness of EVs, including: (1) EVAmerica (a utility program) and DOE conduct performance and evaluation tests to support market development for EVs; (2) DOE, DOT, the Electric Transportation Coalition, and the Electric Vehicle Association of the Americas are conducting a series of workshops to encourage urban groups in Clean Cities (a DOE program) to initiate the policies and infrastructure development necessary to support large-scale demonstrations, and ultimately the mass market use, of EVs. Current focus of the program is collection and dissemination of EV operations and performance data to aid in the evaluation of real- world EV use. This report contains several sections with vehicle evaluation as a focus: EV testing results, energy economics of EVs, and site operators activities.

  3. Considerations for initiating and progressing running programs in obese individuals.

    PubMed

    Vincent, Heather K; Vincent, Kevin R

    2013-06-01

    Running has rapidly increased in popularity and elicits numerous health benefits, including weight loss. At present, no practical guidelines are available for obese persons who wish to start a running program. This article is a narrative review of the emerging evidence of the musculoskeletal factors to consider in obese patients who wish to initiate a running program and increase its intensity. Main program goals should include gradual weight loss, avoidance of injury, and enjoyment of the exercise. Pre-emptive strengthening exercises can improve the strength of the foot and ankle, hip abductor, quadriceps, and trunk to help support the joints bearing the loads before starting a running program. Depending on the presence of comorbid joint pain, nonimpact exercise or walking (on a flat surface, on an incline, and at high intensity) can be used to initiate the program. For progression to running, intensity or mileage increases should be slow and consistent to prevent musculoskeletal injury. A stepwise transition to running at a rate not exceeding 5%-10% of weekly mileage or duration is reasonable for this population. Intermittent walk-jog programs are also attractive for persons who are not able to sustain running for a long period. Musculoskeletal pain should neither carry over to the next day nor be increased the day after exercising. Rest days in between running sessions may help prevent overuse injury. Patients who have undergone bariatric surgery and are now lean can also run, but special foci such as hydration and energy replacement must be considered. In summary, obese persons can run for exercise, provided they follow conservative transitions and progression, schedule rest days, and heed onset of pain symptoms. Copyright © 2013 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  4. Dissemination and Utilization of Vocational Education Program Improvement Products. Phase One, October 1, 1979, through June 30, 1980.

    ERIC Educational Resources Information Center

    Illinois Univ., Urbana. Dept. of Vocational and Technical Education.

    Phase 1 goal of a project was to provide the theoretical and methodological base for formulation of a prototype model of a comprehensive and effective system of disseminating vocational education improvement products. Major activities were divided into five categories: literature reviews, conferences and workshops, consultations, questionnaire…

  5. Bridging the Gap in Implementation Science: Evaluating a Capacity-Building Program in Data Management, Analysis, Utilization, and Dissemination in Low- and Middle-Income Countries.

    PubMed

    Memiah, Peter; Ah Mu, Tristi; Penner, Jeremy; Owour, Kevin; Ngunu-Gituathi, Carol; Prevot, Kourtney; Mochache, Vernon; Wekesa, Paul; Oyore, John; Muhula, Sam; Komba, Patience

    2017-09-08

    Building capacity in implementation science within health programs is dependent on training in theory and practice of epidemiology, statistics, and research in addition to high self-efficacy toward application of training. This article describes a training program providing technical assistance to more than 300 health facilities in Kenya and Tanzania, its evaluation results, and its ability to improve participants' knowledge, competencies, and self-efficacy on data management, analysis, and dissemination among health care professionals. Two months prior to the training, participants (n = 98) were emailed a pre-course survey including 19 questions using a Likert-type response for planning the content of the workshop. Six to 12 weeks after the training, a post-course survey was emailed to all participants. Five different trainings were conducted indicating 5 participant cohorts. The questions posed involved course satisfaction, course impact on knowledge and skills, and self-efficacy in data analysis and utilization. Post-course survey results revealed that the participants had confidence in data analysis, which was significantly different from the pre-test results (0.05 α). Qualitative commentary complemented the findings of the impact of the workshop. Four manuscripts and 13 abstracts have been submitted post training. Results suggest that a short-term training program can achieve immediate gains in data and research self-efficacy among health care professionals. Although increasing self-efficacy is a necessary first step in developing skills, educators should engage in continuing education for sustainable dissemination practices. There is an urgent need to determine the current infrastructure to promote scientific dissemination. This will assist countries to produce better evidence to support their programs, policies, and overall health programs.

  6. Federal Mechanisms to Support Intervention Dissemination.

    PubMed

    Diana, Augusto; Bennett, Nicole

    2015-01-01

    This paper examines federal mechanisms that support program developers and researchers in disseminating effective interventions for public benefit. The purpose of this paper is not to discuss the dissemination of intervention research (i.e., how to inform stakeholders about research findings), nor is it intended to discuss the research of intervention dissemination (i.e., what is the best approach to disseminate an intervention). Rather, the paper discusses the challenges specific to finding pathways to disseminate an intervention and describes federal opportunities to support intervention dissemination. Three specific mechanisms are discussed: Federal Registries of Evidence-Based Programs, the Tiered Evidence Grant Programs, and the Small Business Innovative Research (SBIR) and the Small Technology Transfer Research (STTR) programs. The article presents some limitations associated with federal mechanisms for dissemination of effective interventions, but is intended to highlight current and future opportunities they may offer. © 2015 Wiley Periodicals, Inc.

  7. Progress and Status of the Japan's ISS Program

    NASA Astrophysics Data System (ADS)

    Kozawa, Hideshi

    2002-01-01

    The first element of the International Space Station (ISS) was launched in November 1998. Since then, ISS construction has progressed steadily, and ISS has been operated safely. Since the first permanent crew boarded the ISS in November 2000, various experiments have been conducted. NASDA astronaut Mr. Soichi Noguchi will fly on the STS-114 (ULF1) utilization and supply mission scheduled in early 2003 as a Mission Specialist. Japan is continuing its development and preparation for ISS operation and utilization. The Japanese Experiment Module (JEM) "Kibo" overall system test started in November 2001 at Tsukuba Space Center (TKSC) and it was successfully completed in May 2002. Subsequently, the integration test with the Operation Control System (OCS) has been prepared to verify compatibility with JEM on-board software. The development of the Centrifuge, H-II Transfer Vehicle (HTV) and JEM experiment equipment is also proceeding smoothly. Furthermore, Japan conducted precursor missions as an early utilization program for promoting the JEM research program. An overview of the progress and current status of Japan's Space Station program will be presented.

  8. Ada (Trademark) Joint Program Office Objectives and Progress -- through 1983.

    DTIC Science & Technology

    1984-09-01

    7. AUTHOR(*) S. CONTRACT OR GRANT NUMUER(s) John F. Kramer, Jr. MDA 903 84 C 0031 Catherine W. McDonald S. PERFORMING ORGANIZATION NAME ANO AOORESS...REPORT & PERIOD COVEREO Ada Joint Program Office Objectives and FINAL Progress - Through 1983 6. PERFORMING ORG. REPORT NUMBER IDA Memorandum Report 14...Compiler Conformance 8 1.3.1 Ada Validation organization 8 1.3.2 Ada Compiler Validation Capability 9 1.4 Activities Related to Language Standard 10 1.4.1

  9. Using existing programs as vehicles to disseminate knowledge, provide opportunities for scientists to assist educators, and to engage students in using real data

    NASA Astrophysics Data System (ADS)

    Smith, S. C.; Wegner, K.; Branch, B. D.; Miller, B.; Schulze, D. G.

    2013-12-01

    Many national and statewide programs throughout the K-12 science education environment teach students about science in a hands-on format, including programs such as Global Learning and Observations to Benefit the Environment (GLOBE), Project Learning Tree (PLT), Project Wild, Project Wet, and Hoosier River Watch. Partnering with one or more of these well-known programs can provide many benefits to both the scientists involved in disseminating research and the K-12 educators. Scientists potentially benefit by broader dissemination of their research by providing content enrichment for educators. Educators benefit by gaining understanding in content, becoming more confident in teaching the concept, and increasing their enthusiasm in teaching the concepts addressed. This presentation will discuss an innovative framework for professional development that was implemented at Purdue University, Indiana in July 2013. The professional development incorporated GLOBE protocols with iPad app modules and interactive content sessions from faculty and professionals. By collaborating with the GLOBE program and scientists from various content areas, the Department of Earth, Atmospheric, and Planetary Sciences at Purdue University successfully facilitated a content rich learning experience for educators. Such activity is promoted and supported by Purdue University Libraries where activities such as Purdue's GIS Day are efforts of making authentic learning sustainable in the State of Indiana and for national consideration. Using iPads to visualize soil transitions on a field trip. Testing Water quality in the field.

  10. Progress in the Multijunction Solar Cell Mantech Program

    NASA Technical Reports Server (NTRS)

    Keener, David N.; Marvin, Dean; Brinker, David J.; Curtis, Henry B.

    2004-01-01

    In September, 1995, the joint Wright Laboratory/Phillips Laboratory/NASA Lewis Multijunction Solar Cell Manufacturing Technology (ManTech) Program began to improve multijunction cell performance and scale them up to production size and quantity to support Air Force and commercial satellite programs. The first milestone of the program has been reached and the purpose of this paper is to present the results of the program so far. The objectives of the Multijunction Solar Cell ManTech Program are to increase the GaInP2/GaAs/Ge lot average cell efficiency to 24-26%, increase the cell size to > or equal to 16 sq cm while maintaining high efficiency, and limit the per cell costs to < or equal to 1.15X state of the art GaAs/Ge cells. Advanced manufacturing technology and process control techniques such as in-situ process monitoring and real time process feedback are being used to optimize multijunction solar cell growth processes to achieve these goals. This paper will discuss progress made in Phase I of the program and give an overview of Phase II but will focus on side-by-side testing results collected by Phillips Laboratory and NASA Lewis on Phase I deliverable cells from both vendors. Cell performance, pre- and post radiation, and temperature coefficient results on initial production multijunction solar cells will be presented and discussed. The data shows that this technology meets the objectives of the program, and that, in the interim before a new solar simulation standard becomes widely available, the measurement techniques being used by the major space solar cell manufacturers are providing adequate testing results for solar array design.

  11. Engaging Stakeholders From Volunteer-Led Out-of-School Time Programs in the Dissemination of Guiding Principles for Healthy Snacking and Physical Activity

    PubMed Central

    Koomas, Alyssa; Metayer, Nesly; Fullerton, Karen J.; Hubbard, Kristie L.; Anzman-Frasca, Stephanie; Hofer, Teresa; Nelson, Miriam; Newman, Molly; Sacheck, Jennifer; Economos, Christina

    2015-01-01

    Background Little effort has focused on the role of volunteer-led out-of-school time (OST) programs (ie, enrichment and sports programs) as key environments for the promotion of healthy eating and physical activity habits among school-aged children. The Healthy Kids Out of School (HKOS) initiative developed evidence-based, practical guiding principles for healthy snacks, beverages, and physical activity. The goal of this case study was to describe the methods used to engage regional partners to understand how successful implementation and dissemination of these principles could be accomplished. Community Context HKOS partnered with volunteer-led programs from 5 OST organizations in Maine, Massachusetts, and New Hampshire to create a regional “learning laboratory.” Methods We engaged partners in phases. In the first phase, we conducted focus groups with local volunteer program leaders; during the second phase, we held roundtable meetings with regional and state program administrators; and in the final phase, we conducted additional outreach to refine and finalize implementation strategies. Outcomes Implementation strategies were developed based on themes and information that emerged. For enrichment programs, strategies included new patch and pin programs that were consistent with the organizations’ infrastructure and usual practices. For sports programs, the main strategy was integration with online trainings for coaches. Interpretation Through the engagement process, we learned that dissemination of the guiding principles in these large and complex OST organizations was best accomplished by using implementation strategies that were customized, integrated, and aligned with goals and usual practices. The lessons learned can benefit future efforts to prevent obesity in complex environments. PMID:26704443

  12. Fossil energy program. Progress report for May 1980

    SciTech Connect

    McNeese, L.E.

    1980-08-01

    This report - the seventieth of a series - is a compendium of monthly progress reports for the ORNL research and development programs that are in support of the increased utilization of coal and other fossil fuel alternatives to oil and gas as sources of clean energy. The projects reported this month include those for coal conversion development, chemical research and development, materials technology, component and process evaluation studies, technical support to major liquefaction projects, process analysis and engineering evaluations, fossil energy environmental analysis, coal preparation and waste utilization, coal preparation plant automation, technical support to the TVA fluidized bed combustion demonstration plant program, coal cogeneration/district heating plant assessment, atmospheric fluidized bed coal combustor for cogeneration, performance assurance system support and international energy technology assessment.

  13. Fossil Energy Program. Progress report for April 1980

    SciTech Connect

    McNeese, L.E.

    1980-06-01

    This report - the sixty-ninth of a series - is a compendium of monthly progress reports for the ORNL research and development programs that are in support of the increased utilization of coal and other fossil fuel alternatives to oil and gas as sources of clean energy. The projects reported this month include those for coal conversion development, chemical research and development, materials technology, component and process evaluation studies, technical support to major liquefaction projects, process analysis and engineering evaluations, fossil energy environmental analysis, coal preparation and waste utilization, coal preparation plant automation, atmospheric fluidized bed coal combustor for cogeneration, technical support to the TVA fluidized bed combustion demonstration plant program, coal cogeneration/district heating plant assessment, performance assurance system support, and international energy technology assessment.

  14. Fossil-energy program. Progress report for June 1981

    SciTech Connect

    Not Available

    1981-08-01

    This report - the eighty-third of series - is a compendium of monthly progress reports for the ORNL research and development programs that are in support of the increased utilization of coal and other fossil fuel alternatives as sources of clean energy. The projects reported this month include those for coal conversion development, chemical research and development, materials technology, component development and process evaluation, technical support to major liquefaction projects, process analysis and engineering evaluations, fossil energy environmental analysis, flue gas desulfurization, coal preparation waste utilization, atmospheric fluidized bed coal combustor for cogeneration, TVA FBC demonstration plant program technical support, PFBC systems analysis, fossil fuel applications assessments, performance assurance system support for fossil energy projects, international energy technology assessment, generalized equilibrium models for liquid and gaseous fuel supplies, analyses of coal production goals, and fossil energy information center.

  15. Fossil energy program. Progress report for June 1980

    SciTech Connect

    McNeese, L.E.

    1980-08-01

    This report - the seventy-first of a series - is a compendium of monthly progress reports for the ORNL research and development programs that are in support of the increased utilization of coal and other fossil fuel alternatives to oil and gas as sources of clean energy. The projects reported this month include those for coal conversion development, chemical research and development, materials technology, component and process evaluation studies, technical support to major liquefaction projects, process analysis and engineering evaluation, fossil energy environmental analysis, coal preparation and waste utilization, coal preparation plant automation, atmospheric fluidized bed coal combustor for cogeneration, TVA fluidized combustion demonstration plant program technical support, coal cogeneration/district heating plant assessment, performance assurance system support, and international energy technology assessment.

  16. A Web-Disseminated Self-Help and Peer Support Program Could Fill Gaps in Mental Health Care: Lessons From a Consumer Survey

    PubMed Central

    Banschback, Kaitlin; Santorelli, Gennarina D; Constantino, Michael J

    2017-01-01

    Background Self-guided mental health interventions that are disseminated via the Web have the potential to circumvent barriers to treatment and improve public mental health. However, self-guided interventions often fail to attract consumers and suffer from user nonadherence. Uptake of novel interventions could be improved by consulting consumers from the beginning of the development process in order to assess their interest and their preferences. Interventions can then be tailored using this feedback to optimize appeal. Objective The aim of our study was to determine the level of public interest in a new mental health intervention that incorporates elements of self-help and peer counseling and that is disseminated via a Web-based training course; to identify predictors of interest in the program; and to identify consumer preferences for features of Web-based courses and peer support programs. Methods We surveyed consumers via Amazon’s Mechanical Turk to estimate interest in the self-help and peer support program. We assessed associations between demographic and clinical characteristics and interest in the program, and we obtained feedback on desired features of the program. Results Overall, 63.9% (378/592) of respondents said that they would try the program; interest was lower but still substantial among those who were not willing or able to access traditional mental health services. Female gender, lower income, and openness to using psychotherapy were the most consistent predictors of interest in the program. The majority of respondents, although not all, preferred romantic partners or close friends as peer counselors and would be most likely to access the program if the training course were accessed on a stand-alone website. In general, respondents valued training in active listening skills. Conclusions In light of the apparent public interest in this program, Web-disseminated self-help and peer support interventions have enormous potential to fill gaps in

  17. Progress and Priorities of the US AMOC Program

    NASA Astrophysics Data System (ADS)

    Patterson, M. W.; Danabasoglu, G.; Uhlenbrock, K.

    2014-12-01

    Now in its seventh year, the US AMOC program aims to develop an improved understanding of the mechanisms behind fluctuations of the Atlantic Meridional Overturning Circulation (AMOC), leading to new capabilities for monitoring and predictions of AMOC and its influence on climate. The program is implemented by a Science Team, comprised of over 100 investigators on 60+ projects funded by NASA, NOAA, NSF, and DoE. The Science Team meets annually to share research advances, foster collaborations, and determine near-term priorities to address four objectives: implementation and evaluation of an AMOC observing system; assessment of AMOC state, variability, and change; assessment of AMOC mechanisms and predictability; and assessment of the role of AMOC in the global climate and ecosystems. The US AMOC program also seeks to develop and strengthen collaborations with the broader Earth system community, particularly with: paleo-oceanography to enable centennial-scale reconstructions and fingerprinting of AMOC; cryospheric sciences to understand the accelerating changes in Arctic sea ice extent and Greenland ice sheet mass, and the impact of fresh melt water on North Atlantic circulation and regional sea level rise; and ocean biogeochemistry for understanding carbon cycle changes and ecosystem impacts. We will highlight progress on the program objectives as well as updated near- and long-term priorities for future research emerging from the September 2014 meeting of Science Team.

  18. Dissemination of evidence-based mental health interventions: importance to the trauma field.

    PubMed

    Katon, Wayne J; Zatzick, Doug; Bond, Gary; Williams, John

    2006-10-01

    Randomized controlled trials have established the efficacy of psychotherapy and medication treatments for posttraumatic stress disorder (PTSD). Despite these advancements, many individuals do not receive guideline-concordant PTSD care. In an effort to advance dissemination of evidence-based PTSD treatments, the authors review several examples of dissemination efforts of mental health interventions. The first examples describe the dissemination of multifaceted collaborative care interventions for patients with depressive disorders and evidence-based interventions for patients with severe mental illness. The final example explores evolving efforts to adapt and disseminate interventions to acutely injured trauma survivors. For each example, the authors describe the problem with prior clinical approaches, the program to be disseminated, the barriers and levers to implementation and the progress in overcoming these barriers.

  19. Dissemination of go sun smart in outdoor recreation: effect of program exposure on sun protection of guests at high-altitude ski areas.

    PubMed

    Walkosz, Barbara J; Buller, David B; Andersen, Peter A; Scott, Michael D; Dignan, Mark B; Cutter, Gary R; Liu, Xia; Maloy, Julie A

    2014-09-01

    Go Sun Smart is a theory-based health communication program designed to influence sun-protection behaviors of employees and guests at high-altitude ski areas to reduce skin cancer risk. The effects of Go Sun Smart, in a Phase IV dissemination randomized posttest-only trial, on sun-protection behaviors of ski area guests are reported. Program use was assessed by on-site observation and guest message exposure, and sun protection was measured in intercept surveys at ski areas. Dissemination strategy-enhanced versus basic-was not significantly related to sun safety practices. Additional analyses examined the relation between message exposure and guests' sun safety practices. Ski areas displaying at least 6 Go Sun Smart materials in guest-only areas and 9 Go Sun Smart materials throughout the area increased guests' message exposure. Higher message exposure within the high-use ski areas was associated with improved sun protection by guests but not within the low-use ski areas. The authors underscore the importance of program implementation and message exposure on the success of evidence-based health communication efforts applied industrywide.

  20. Dissemination of Go Sun Smart in Outdoor Recreation: Effect of Program Exposure on Sun Protection of Guests at High Altitude Ski Areas

    PubMed Central

    WALKOSZ, BARBARA J.; BULLER, DAVID B.; ANDERSEN, PETER A.; SCOTT, MICHAEL D.; DIGNAN, MARK B.; CUTTER, GARY R.; LIU, XIA; MALOY, JULIE A.

    2014-01-01

    Go Sun Smart (GSS) is a theory-based health communication program designed to influence sun protection behaviors of employees and guests at high altitude ski areas to reduce skin cancer risk. The effects of GSS, in a Phase IV dissemination randomized posttest-only trial, upon sun protection behaviors of ski area guests are reported. Program use was assessed by on-site observation and guest message exposure and sun protection was measured in intercept surveys at ski areas. Dissemination strategy, enhanced versus basic, was not significantly related to sun safety practices. Additional analyses examined the relationship of message exposure to guests’ sun safety practices. Ski areas displaying at least 6 GSS materials in guest-only areas and 9 GSS materials throughout the area increased guests’ message exposure. Higher message exposure within the high-use ski areas was associated with improved sun protection by guests but not in the low-use ski areas. The importance of program implementation and message exposure on the success of evidence-based health communication efforts applied industry-wide are underscored. PMID:24617350

  1. Progress report on the Worldwide Earthquake Risk Management (WWERM) Program

    USGS Publications Warehouse

    Algermissen, S.T.; Hays, Walter W.; Krumpe, Paul R.

    1992-01-01

    Considerable progress has been made in the Worldwide Earthquake Risk Management (WWERM) Program since its initiation in late 1989 as a cooperative program of the Agency for International Development (AID), Office of U.S. Foreign Disaster Assistance (OFDA), and the U.S. Geological Survey. Probabilistic peak acceleration and peak Modified Mercalli intensity (MMI) maps have been prepared for Chile and for Sulawesi province in Indonesia. Earthquake risk (loss) studies for dwellings in Gorontalo, North Sulawesi, have been completed and risk studies for dwellings in selected areas of central Chile are underway. A special study of the effect of site response on earthquake ground motion estimation in central Chile has also been completed and indicates that site response may modify the ground shaking by as much as plus or minus two units of MMI. A program for the development of national probabilistic ground motion maps for the Philippines is now underway and pilot studies of earthquake ground motion and risk are being planned for Morocco.

  2. Accelerator technology program. Progress report, January-December 1979

    SciTech Connect

    Knapp, E.A.; Jameson, R.A.

    1980-11-01

    The activities of Los Alamos Scientific Laboratory's (LASL) Accelerator Technology (AT) Division during the calendar year 1979 are highlighted, with references to more detailed reports. This report is organized around the major projects of the Division, reflecting a wide variety of applications and sponsors. The first section covers the Fusion Materials Irradiation Test program, a collaborative effort with the Hanford Engineering Development Laboratory; the second section summarizes progress on the Proton Storage Ring to be built between LAMPF and the LASL Pulsed Neutron Research facility. A new project that achieved considerable momentum during the year is described next - the free-electron laser studies; the following section discusses the status of the Pion Generator for Medical Irradiation program. Next, two more new programs, the racetrack microtron being developed jointly by AT-Division and the National Bureau of Standards and the radio-frequency (rf) accelerator development for heavy ion fusion, are outlined. Development activities on a new type of high-power, high-efficiency rf amplifier called the gyrocon are then reported, and the final sections cover development of H/sup -/ ion sources and injectors, and linear accelerator instrumentation and beam dynamics.

  3. Integrating Research, Quality Improvement, and Medical Education for Better Handoffs and Safer Care: Disseminating, Adapting, and Implementing the I-PASS Program.

    PubMed

    Starmer, Amy J; Spector, Nancy D; West, Daniel C; Srivastava, Rajendu; Sectish, Theodore C; Landrigan, Christopher P

    2017-07-01

    In 2009 the I-PASS Study Group was formed by patient safety, medical education, health services research, and clinical experts from multiple institutions in the United States and Canada. When the I-PASS Handoff Program, which was developed by the I-PASS Study Group, was implemented in nine hospitals, it was associated with a 30% reduction in injuries due to medical errors and significant improvements in handoff processes, without any adverse effects on provider work flow. To effectively disseminate and adapt I-PASS for use across specialties and disciplines, a series of federally and privately funded dissemination and implementation projects were carried out following the publication of the initial study. The results of these efforts have informed ongoing initiatives intended to continue adapting and scaling the program. As of this writing, I-PASS Study Group members have directly worked with more than 50 hospitals to facilitate implementation of I-PASS. To further disseminate I-PASS, Study Group members delivered hundreds of academic presentations, including plenaries at scientific meetings, workshops, and institutional Grand Rounds. Some 3,563 individuals, representing more than 500 institutions in the 50 states in the United States, the District of Columbia, Puerto Rico, and 57 other countries, have requested access to I-PASS materials. Most recently, the I-PASS(SM) Patient Safety Institute has developed a virtual immersion training platform, mobile handoff observational tools, and processes to facilitate further spread of I-PASS. Implementation of I-PASS has been associated with substantial improvements in patient safety and can be applied to a variety of disciplines and types of patient handoffs. Widespread implementation of I-PASS has the potential to substantially improve patient safety in the United States and beyond. Copyright © 2017 The Joint Commission. Published by Elsevier Inc. All rights reserved.

  4. Microenvironments and Signaling Pathways Regulating Early Dissemination, Dormancy, and Metastasis

    DTIC Science & Technology

    2015-09-01

    Andreas Hartkopf, Florin-Andrei Taran, Tanja Fehm, Gunter Meister, Christoph A. Klein. “Her2 and progesterone signaling cooperate for early dissemination... progesterone receptor-B (PgR) favored side branching (Brisken et al., 2000). With Hosseini et al., we also found that PgR signaling is enriched in the pre...signaling in early stages of breast cancer progression may awaken programs of motility, invasion and stem cell-like behavior observed during pregnancy

  5. DIII--D National Program Progress and Plans

    NASA Astrophysics Data System (ADS)

    Simonen, T. C.

    1997-11-01

    The DIII--D Advanced Tokamak (AT) program uses and advances fusion energy science to provide the basis for future fusion initiatives. DIII--D experiments have employed particle and current profile control to optimize performance of short pulse DIII--D plasmas. The new capabilities of high triangularity divertor pumping and neutral particle baffling together with 110 GHz ECH power provide means to further optimize and extend these plasmas toward steady-state. DIII--D experiments are critically testing theory-based modelings, increasing plasma stability and its theoretical underpinning, developing divertor understanding through new experiments and measurements benchmarking modeling codes, and developing methods for tailoring the tokamak plasma current profile. Progress on these science fronts, which guides the future integrated DIII--D research plan, will be described.

  6. GRAD: a tool for program analysis and progress monitoring

    SciTech Connect

    Yen, W.W.S.; Lawrence, J.D.

    1981-06-01

    Information required for development, monitoring, and evaluation of Federal geothermal programs is extensive, and is needed on a timely basis to optimize the allocation of resources. This paper describes the development and operation of the Geothermal Resource Areas Database (GRAD). GRAD was created as part of the National Geothermal Progress Monitor System in 1979. The database is organized around the concept of a geothermal area and provides broad coverage of geothermal development activities in the United States. Sixteen records, covering pre-lease, lease, and post-lease activities have been defined for each area. Data collected in the various subject areas are critically evaluated, and then entered into an on-line interactive computer system. The system is publicly available for retrieval and use.

  7. Inertial Fusion Program. Progress report, January-December 1980

    SciTech Connect

    Not Available

    1982-05-01

    This report summarizes research and development effort in support of the Inertial Confinement Fusion program, including absorption measurements with an integrating sphere, generation of high CO/sub 2/-laser harmonics in the backscattered light from laser plasmas, and the effects of hydrogen target contamination on the hot-electron temperature and transport. The development of new diagnostics is outlined and measurements taken with a proximity-focused x-ray streak camera are presented. High gain in phase conjugation using germanium was demonstrated, data were obtained on retropulse isolation by plasmas generated from metal shutters, damage thresholds for copper mirrors at high fluences were characterized, and phase conjugation in the ultraviolet was demonstrated. Significant progress in the characterization of targets, new techniques in target coating, and important advances in the development of low-density, small-cell-size plastic foam that permit highly accurate machining to any desired shape are presented. The results of various fusion reactor system studies are summarized.

  8. Inertial Fusion Program. Progress report, July 1-December 31, 1979

    SciTech Connect

    Skoberne, F.

    1981-10-01

    Progress in the development of high-energy short-pulse CO/sub 2/ laser systems for fusion research is reported. Improvements in the Los Alamos National Laboratory eight-beam Helios system are described. These improvements increased the reliability of the laser and permitted the firing of 290 shots, most of which delivered energies of approximately 8 kJ to the target. Modifications to Gemini are outlined, including the installation of a new target-insertion mechanism. The redirection of the Antares program is discussed in detail, which will achieve a total energy of approximatey 40 kJ with two beams. This redirection will bring Antares on-line almost two years earlier than was possible with the full six-beam system, although at a lower energy. Experiments with isentropically imploded Sirius-B targets are discussed, and x-ray radiation-loss data from gold microballoons are presented, which show that these results are essentially identical with those obtained at glass-laser wavelengths. Significant progress in characterizing laser fusion targets is reported. New processes for fabricating glass miroballoon x-ray diagnostic targets, the application of high-quality metallic coatings, and the deposition of thick plastic coatings are described. Results in the development of x-ray diagnostics are reported, and research in the Los Alamos heavy-ion fusion program is summarized. Results of investigations of phase-conjugation research of gaseous saturable absorbers and of the use of alkali-halide crystals in a new class of saturable absorbers are summarized. New containment-vessel concepts for Inertial Confinement Fusion reactors are discussed, and results of a scoping study of four fusion-fission hybrid concepts are presented.

  9. Development of Curriculum for a Non-Traditional Machine Tool Technology Program Accessible to the Physically Handicapped. Dissemination Report.

    ERIC Educational Resources Information Center

    Chabot Coll., Hayward, CA.

    This report of a project to develop curricula for a model program for computerized numerical control in the machine tool technology area begins with a discussion of accessibility in vocational/technical programs. An overview of the laws requiring program accessibility is provided. Problems encountered in program accessibility and their solutions…

  10. Quarterly Program Progress Report April 1, 2002-June 30, 2002

    SciTech Connect

    Palafox, Neal A., MD, MPH

    2002-07-31

    DOE B188 DOE/PHRI Special Medical Care Program in the Republic of the Marshall Islands (RMI)Quarterly Program Progress Report The DOE/PHRI Special Medical Care Program continues to provide, on a year round basis, a broad spectrum of medical care to the DOE patient population. During the fourth quarter of Year 4, the following medical services were provided: (1) Annual medical examinations for the DOE patient population (see Exhibit 1 for details). (2) Medications for the DOE patient population. (3) Preventive and primary medical care to the DOE patient population in the RMI as time and resources permit. (4) Additional manpower for the outpatient clinics at Ebeye and Majuro Hospitals (see Exhibit 2 for details). (5) Ancillary services such as labs, radiology and pharmacy in coordination with Kwajalein Hospital, Majuro Hospital and the 177 Health Care Program (177 HCP). (6) Referrals to Ebeye Hospital, Majuro Hospital and Kwajalein Hospital as necessary. (7) Referrals to Straub Clinic and Hospital in Honolulu as necessary (for details see Exhibit 1). (8) Monitored and adjusted monthly annual examination schedules based on equipment failure at Kwajalein. In addition to the above, the program was also involved in the following activities during this quarter: (1) Organized and conducted continuing medical education (CME) talks for the program's RMI staff and other RMI healthcare workers. (2) Held meetings with RMI government officials and Local Atoll government officials. (3) Input past medical records into the Electronic Medical Record (EMR) system. (4) Made adjustments to and created more templates for the EMR system. (5) Coordinated with the Public Health Departments on Majuro and Ebeye. (6) Met with PEACESAT to discuss possible collaboration on high speed Internet access. (7) Looked for opportunities to expand the program's telehealth capabilities. (8) Participated in the DOE-RMI Meeting in Honolulu. (9) Finalized the agreement with the RMI Ministry of Health and

  11. Disseminated extracranial metastatic meningioma.

    PubMed

    Chua, Felicia H Z; Low, Sharon Y Y; Tham, Chee K; Ding, Cristine; Wong, Chin F; Nolan, Colum P

    2016-11-01

    Meningiomas are usually low-grade, solitary lesions that rarely metastasize. In this group of central nervous system tumours, the higher grade subtypes are notorious for resistance to conventional chemo-radiation therapies. Recent studies have shown efficacy in the use of bevacizumab in patients with recurrent and, or progressive anaplastic meningioma. The authors report a case of a young patient with recurrent anaplastic meningioma who despite being treated with bevacizumab, progressed with disease dissemination to multiple extracranial sites. Although the majority of meningiomas are amendable to treatment, the higher grade subtypes remain therapeutically challenging. The unexpected resistance to anti-angiogenic therapy in this patient adds another layer of complexity to an elusive subset of a supposedly benign disease. This patient report reflects the need for in-depth studies, molecular characterization and overall, better disease understanding in order to improve prognosis for affected patients. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. The Tenth National Dissemination Conference. A Report.

    ERIC Educational Resources Information Center

    Herlig, Richard K.

    This report on the Tenth National Dissemination Conference of 1977 outlines the purposes of the conference and summarizes the present state of educational information dissemination. National programs are described, including the National Institute of Education State Capacity Building Program, the National Diffusion Network, the Dissemination…

  13. Final report. Geothermal Energy Program: Information dissemination, public outreach, and technical analysis activities. April 1, 1999 to December 31, 2001. USDOE Grant No. DE-FG01-99-EE35098

    SciTech Connect

    Lund, John W.

    2002-03-22

    This is the final report of the accomplishments of the geothermal energy program: information dissemination, public outreach, and technical analysis activities by the project team consisting of the Geo-Heat Center, Geothermal Resources Council, Geothermal Education Office, Geothermal Energy Association, and the Washington State University Energy Program.

  14. Innovative and Community-Guided Evaluation and Dissemination of a Prostate Cancer Education Program for African-American Men and Women

    PubMed Central

    Jackson, Dawnyea D.; Owens, Otis L.; Friedman, Daniela B.; Dubose-Morris, Ragan

    2014-01-01

    African Americans (AA) are more likely to develop and die from cancer than any other racial or ethnic group. The aims of this research were to: (1) evaluate current education materials being implemented in a community-based prostate cancer education program for AA communities; (2) refine materials based on findings from Aim 1; (3) share updated materials with participants from Aim 1 for additional improvements; and (4) disseminate and evaluate the improved education program through a statewide videoconference with AA men and women. AA individuals evaluated the current education program through a mail survey (n=32) and community forum (n=38). Participants reported that the existing prostate cancer education program content could be understood by lay persons, but recommendations for improvement were identified. They included: defining unknown and/or scientific terminology, increasing readability by increasing font size and enlarging images, and including more recent and relevant statistics. Following refinement of the education materials based on survey and forum feedback, a statewide videoconference was implemented. Following the videoconference, participants (25 men; 3 women) reported that they would encourage others to learn more about prostate cancer, talk to their doctor about whether or not to get screened for prostate cancer, and would recommend the conference to others. There is great potential for using this type of iterative approach to education program development with community and clinical partners for others conducting similar work. PMID:25510370

  15. Innovative and Community-Guided Evaluation and Dissemination of a Prostate Cancer Education Program for African-American Men and Women.

    PubMed

    Jackson, Dawnyea D; Owens, Otis L; Friedman, Daniela B; Dubose-Morris, Ragan

    2015-12-01

    African Americans (AA) are more likely to develop and die from cancer than any other racial or ethnic group. The aims of this research were to (1) evaluate current education materials being implemented in a community-based prostate cancer education program for AA communities, (2) refine materials based on findings from aim 1, (3) share updated materials with participants from aim 1 for additional improvements, and (4) disseminate and evaluate the improved education program through a statewide videoconference with AA men and women. AA individuals evaluated the current education program through a mail survey (n=32) and community forum (n=38). Participants reported that the existing prostate cancer education program content could be understood by lay persons, but recommendations for improvement were identified. They included the following: defining unknown and/or scientific terminology, increasing readability by increasing font size and enlarging images, and including more recent and relevant statistics. Following refinement of the education materials based on survey and forum feedback, a statewide videoconference was implemented. Following the videoconference, participants (25 men; 3 women) reported that they would encourage others to learn more about prostate cancer, talk to their doctor about whether or not to get screened for prostate cancer, and recommend the conference to others. There is great potential for using this type of iterative approach to education program development with community and clinical partners for others conducting similar work.

  16. Progress Cleaning the Air: Voluntary Partnership Program Accomplishments

    EPA Pesticide Factsheets

    EPA voluntary clean air partnership programs work in tandem with regulatory programs to protect public health and the environment. This page highlights accomplishments of selected partnership programs.

  17. COSMIC monthly progress report

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Activities of the Computer Software Management and Information Center (COSMIC) are summarized for the month of January 1994. Tables showing the current inventory of programs available from COSMIC are presented and program processing and evaluation activities are discussed. Marketing and customer service activities in this period are presented as is the progress report of NASTRAN maintenance and support. Tables of disseminations and budget summary conclude the report.

  18. Hydrologic resources management program, FY 1998 progress report

    SciTech Connect

    Benedict, F.C.; Criss, R.E.; Davisson, M.L.; Eaton, G.F.; Hudson, G.B.; Kenneally, J.M.; Rose, T.P.; Smith, D.

    1999-07-26

    This report presents the results from FY 1998 technical studies conducted by Lawrence Livermore National Laboratory (LLNL) as part of the Hydrology and Radionuclide Migration Program (HRMP) and Underground Test Area (UGTA) project. The HRMP is sponsored by Defense Programs (DP) of the U.S. Department of Energy, Nevada Operations Office (DOE/NV), and supports DP operations at the Nevada Test Site (NTS) through studies of radiochemistry and resource management related to the defense programs mission. Other participating organizations include the Los Alamos National Laboratory (LANL), the United States Geological Survey (USGS), the Desert Research Institute (DRI) of the University of Nevada, the United States Environmental Protection Agency (EPA), and Bechtel-Nevada (BN). The UGTA project is an Environmental Management (EM) activity of DOE/NV that supports a Federal Facilities Agreement and Consent Order between the Department of Energy, the Department of Defense, and the State of Nevada. UGTA's primary function is to address the legacy release of hazardous constituents at the Nevada Test Site, the Tonopah Test Range, and off-Nevada Test Site underground nuclear testing areas. Participating contractors include LLNL (Earth and Environmental Sciences Directorate, Analytical and Nuclear Chemistry Division), LANL, DRI, USGS, BN, HSI-GeoTrans, and IT Corporation. The FY 1998 HRMP and UGTA annual progress report follows the organization and contents of our FY 1997 report (Smith et al., 1998), and includes our results from CY 1997-1998 technical studies of radionuclide migration and isotope hydrology at the Nevada Test Site. During FY 1998, LLNL continued its efforts under the HRMP to pursue a technical agenda relevant to the science-based stockpile stewardship program at DOE/NV. Support to UGTA in FY 1998 included efforts to quantitatively define the radionuclide source term residual from underground nuclear weapons testing and the derivative solution, or hydrologic source

  19. Progress on the European gas turbine program AGATA

    SciTech Connect

    Gabrielsson, R.; Holmqvist, G.

    1998-01-01

    The four-year European Gas Turbine Program AGATA was started in January 1993 with the objective of developing three critical components aimed at a 60 kW turbogenerator in an hybrid electric vehicle: a catalytic combustor, a radial turbine wheel and a static heat exchanger. The AGATA partners represent car manufacturers as well as companies and research institutes in the turbine, catalyst, and ceramic material fields in both France and Sweden. This paper outlines the main results of the AGATA project for the first three-year period. Experimental verification of the components started during the third year of the program. A high-pressure/temperature test rig for the combustor and the heat exchanger tests has been built and is now being commissioned. A high-temperature turbine spin rig will be ready late 1995. The turbine wheel design is completed and ceramic Si{sub 3}N{sub 4} spin disks have been manufactured by injection molding and Hot Isostatic Pressing (HIP). A straight blade design has been selected and FEM calculations have indicated that stress levels that occur during a cold start are below 300 MPa. The catalytic combustor final design for full-scale testing has been defined. Due to the high operating temperature, 1350 C, catalyst pilot tests have included aging, activity, and strength tests. Based on these tests, substrate and active materials have been selected. Initial full-scale tests including LDV measurements in the premix duct will start late 1995. The heat exchanger design has also been defined. This is based on a high-efficiency plate recuperator design. One critical item is the ceramic thermoplastic extrusion manufacturing method for the extremely thin exchanger plates another is the bonding technique: ceramic to ceramic and ceramic to metal. significant progress on these two items has been achieved. The manufacturing of quarter scale prototypes is now in process.

  20. Piloting a nationally disseminated, interactive human subjects protection program for community partners: unexpected lessons learned from the field.

    PubMed

    Solomon, Stephanie; Bullock, Sherita; Calhoun, Karen; Crosby, Lori; Eakin, Brenda; Franco, Zeno; Hardwick, Emily; Holland, Samuel; Leinberger-Jabari, Andrea; Newton, Gail; Odell, Jere; Paberzs, Adam; Spellecy, Ryan

    2014-04-01

    Funders, institutions, and research organizations are increasingly recognizing the need for human subjects protections training programs for those engaged in academic research. Current programs tend to be online and directed toward an audience of academic researchers. Research teams now include many nonacademic members, such as community partners, who are less likely to respond to either the method or the content of current online trainings. A team at the CTSA-supported Michigan Institute for Clinical and Health Research at the University of Michigan developed a pilot human subjects protection training program for community partners that is both locally implemented and adaptable to local contexts, yet nationally consistent and deliverable from a central administrative source. Here, the developers of the program and the collaborators who participated in the pilot across the United States describe 10 important lessons learned that align with four major themes: The distribution of the program, the implementation of the program, the involvement of community engagement in the program, and finally lessons regarding the content of the program. These lessons are relevant to anyone who anticipates developing or improving a training program that is developed in a central location and intended for local implementation. © 2014 Wiley Periodicals, Inc.

  1. Piloting a Nationally Disseminated, Interactive Human Subjects Protection Program for Community Partners: Unexpected Lessons Learned from the Field

    PubMed Central

    Bullock, Sherita; Calhoun, Karen; Crosby, Lori; Eakin, Brenda; Franco, Zeno; Hardwick, Emily; Leinberger‐Jabari, Andrea; Newton, Gail; Odell, Jere; Paberzs, Adam; Spellecy, Ryan

    2014-01-01

    Abstract Funders, institutions, and research organizations are increasingly recognizing the need for human subjects protections training programs for those engaged in academic research. Current programs tend to be online and directed toward an audience of academic researchers. Research teams now include many nonacademic members, such as community partners, who are less likely to respond to either the method or the content of current online trainings. A team at the CTSA‐supported Michigan Institute for Clinical and Health Research at the University of Michigan developed a pilot human subjects protection training program for community partners that is both locally implemented and adaptable to local contexts, yet nationally consistent and deliverable from a central administrative source. Here, the developers of the program and the collaborators who participated in the pilot across the United States describe 10 important lessons learned that align with four major themes: The distribution of the program, the implementation of the program, the involvement of community engagement in the program, and finally lessons regarding the content of the program. These lessons are relevant to anyone who anticipates developing or improving a training program that is developed in a central location and intended for local implementation. PMID:24720349

  2. Accelerator Technology Program. Progress report, January-June 1980

    SciTech Connect

    Knapp, E.A.; Jameson, R.A.

    1980-03-01

    The activities of Los Alamos Scientific Laboratory's (LASL) Accelerator Technology (AT) Division during the first six months of calendar 1980 are discussed. This report is organized around major projects of the Division, reflecting a wide variety of applications and sponsors. The first section summarizes progress on the Proton Storage Ring to be located between LAMPF and the LASL Pulsed Neutron Research facility, followed by a section on the gyrocon, a new type of high-power, high-efficiency radio-frequency (rf) amplifier. The third section discusses the racetrack microtron being developed jointly by AT Division and the National Bureau of Standards; the fourth section concerns the free-electron studies. The fifth section covers the radio-frequency quadrupole linear accelerator, a new concept for the acceleration of low-velocity particles; this section is followed by a section discussing heavy ion fusion accelerator development. The next section reports activities in the Fusion Materials Irradiation Test program, a collaborative effort with the Hanford Engineering Development Laboratory. The final section deals first with development of H/sup -/ ion sources and injectors, then with accelerator instrumentation and beam dynamics.

  3. Progress in the Advanced Synthetic-Diamond Drill Bit Program

    SciTech Connect

    Glowka, D.A.; Dennis, T.; Le, Phi; Cohen, J.; Chow, J.

    1995-11-01

    Cooperative research is currently underway among five drill bit companies and Sandia National Laboratories to improve synthetic-diamond drill bits for hard-rock applications. This work, sponsored by the US Department of Energy and individual bit companies, is aimed at improving performance and bit life in harder rock than has previously been possible to drill effectively with synthetic-diamond drill bits. The goal is to extend to harder rocks the economic advantages seen in using synthetic-diamond drill bits in soft and medium rock formations. Four projects are being conducted under this research program. Each project is investigating a different area of synthetic diamond bit technology that builds on the current technology base and market interests of the individual companies involved. These projects include: optimization of the PDC claw cutter; optimization of the Track-Set PDC bit; advanced TSP bit development; and optimization of impregnated-diamond drill bits. This paper describes the progress made in each of these projects to date.

  4. Demystifying the Publication Process--A Structured Writing Program to Facilitate Dissemination of Teaching and Learning Scholarship

    ERIC Educational Resources Information Center

    Weaver, Debbi; Robbie, Diane; Radloff, Alex

    2014-01-01

    This paper reports on a writing program to support academic staff to publish in peer-refereed journals. Nine participants completed a 12-week program, which involved regular meetings, set writing tasks, and peer feedback on drafts. A pre- and post-survey and follow-up interviews were used to gather feedback. Participants especially valued the…

  5. Demystifying the Publication Process--A Structured Writing Program to Facilitate Dissemination of Teaching and Learning Scholarship

    ERIC Educational Resources Information Center

    Weaver, Debbi; Robbie, Diane; Radloff, Alex

    2014-01-01

    This paper reports on a writing program to support academic staff to publish in peer-refereed journals. Nine participants completed a 12-week program, which involved regular meetings, set writing tasks, and peer feedback on drafts. A pre- and post-survey and follow-up interviews were used to gather feedback. Participants especially valued the…

  6. Conflict of Interest in the Evaluation and Dissemination of “Model” School-based Drug and Violence Prevention Programs

    PubMed Central

    Gorman, Dennis M.; Conde, Eugenia

    2010-01-01

    Conflict of interest refers to a set of conditions in which professional judgment concerning the validity of research might be influenced by a secondary competing interest. The competing interest that has received most attention in the literature addressing the prevalence and effects of such conflicts on the practice of empirical research has been that of financial relationships between investigators and research sponsors. The potential for conflicts of interest to arise in the evaluation of drug prevention programs was raised by Moskowitz in this journal in 1993, but to date there has been no attempt made to estimate the scope of this problem. The present study addressed this issue using a sample of “model” school-based drug and violence prevention interventions by first, identifying the types or relationships that exist between program developers and program distributors, and, second, by assessing how many of the evaluations of these programs published in peer-reviewed journals had been conducted by the developers of the programs compared to independent evaluation teams. The data presented indicate that there are relatively few published evaluations that do not involve program developers and that there are few instances in which there is complete separation between the program developer and program distributor. Using the open systems model of the Institute of Medicine Committee on Research Integrity as a framework, it is argued that the culture and norms of the program developer and those of the program evaluator are fundamentally distinct and therefore failure to separate these roles produces high potential for conflict of interest to arise. PMID:17945143

  7. Consolidated fuel reprocessing. Program progress report, April 1-June 30, 1980

    SciTech Connect

    Not Available

    1980-09-01

    This progress report is compiled from major contributions from three programs: (1) the Advanced Fuel Recycle Program at ORNL; (2) the Converter Fuel Reprocessing Program at Savannah River Laboratory; and (3) the reprocessing components of the HTGR Fuel Recycle Program, primarily at General Atomic and ORNL. The coverage is generally overview in nature; experimental details and data are limited.

  8. The Adult Basic Education Program: Progress in Reducing Illiteracy and Improvements Needed. Report to the Congress.

    ERIC Educational Resources Information Center

    Comptroller General of the U.S., Washington, DC.

    Adult basic education programs in California, Illinois, North Carolina, Texas, and Virginia were reviewed to assess the progress made by the programs in reducing illiteracy. The programs' management was also evaluated. It was found that although some positive achievements have been made, the program successfully reaches only a small fraction of…

  9. FY13 Annual Progress Report for SECA Core Technology Program

    SciTech Connect

    Stevenson, Jeffry W.; Koeppel, Brian J.

    2014-01-31

    This progress report covers technical work performed during fiscal year 2013 at PNNL under Field Work Proposal (FWP) 40552. The report highlights and documents technical progress in tasks related to advanced cell and stack component materials development and computational design and simulation. Primary areas of emphasis for the materials development work were metallic interconnects and coatings, cathode and anode stability/degradation, glass seals, and advanced testing under realistic stack conditions: Metallic interconnects and coatings • Effects of surface modifications to AISI 441 (prior to application of protective spinel coatings) on oxide scale growth and adhesion were evaluated as a function of temperature and time. Cathode stability/degradation • Effects of cathode air humidity on performance and stability of SOFC cathodes were investigated by testing anode-supported cells as a function of time and temperature. • In-situ high temperature XRD measurements were used to correlate changes in cathode lattice structure and composition with performance of anode-supported button cells. Anode stability/degradation • Effects of high fuel steam content on Ni/YSZ anodes were investigated over a range of time and temperature. • Vapor infiltration and particulate additions were evaluated as a potential means of improving tolerance of Ni/YSZ anodes to sulfur-bearing fuel species. Glass seals • A candidate compliant glass-based seal materials were evaluated in terms of microstructural evolution and seal performance as a function of time and temperature. Stack fixture testing • The SECA CTP stack test fixture was used for intermediate and long-term evaluation of candidate materials and processes. Primary areas of emphasis for the computational modeling work were coarse methodology, degradation of stack components, and electrochemical modeling: Coarse methodology • Improvements were made to both the SOFC-MP and SOFC ROM simulation tools. Degradation of stack

  10. Harnessing Protocolized Adaptation in Dissemination: Successful Implementation and Sustainment of the Veterans Affairs Coordinated-Transitional Care (C-TraC) Program in a Non- Veterans Affairs Hospital

    PubMed Central

    Kind, Amy J.H.; Brenny-Fitzpatrick, Maria; Leahy-Gross, Kris; Mirr, Jacquelyn; Chapman, Elizabeth; Frey, Brooke; Houlahan, Beth

    2015-01-01

    The low-cost, primarily phone-based Coordinated-Transitional Care (C-TraC) program reduced 30-day rehospitalizations by 1/3, leading to significant cost savings at one VA hospital. Non-VA hospitals have expressed interest in launching C-TraC, but non-VA hospitals differ in important ways from VA hospitals, particularly in terms of context, culture and resources. The objective of this project was to successfully adapt C-TraC to the specific context of one non-VA setting using a modified Replicating Effective Programs (REP) implementation theory model, and to test the feasibility of this protocolized implementation approach. The modified-REP model 1) uses a mentored phased-based implementation with intensive pre-implementation activities, and 2) harnesses local key stakeholders to adapt processes and goals to local context. Using this protocolized implementation approach, an adapted C-TraC protocol was created and launched at the non-VA hospital in July 2013. In its first 16 months, C-TraC successfully enrolled 1,247 patients with 3.2 full-time nurse case managers, achieving good fidelity for core protocol steps. C-TraC patients experienced a 30-day rehospitalization rate of 10.8%, as compared to 16.6% for a contemporary comparison group of similar patients for whom C-TraC was not available (n=1,307) [p-value < 0.001]. The new C-TraC program continues in operation to this day. In conclusion, use of a modified REP model to guide protocolized adaptation to local context resulted in a C-TraC program that was feasible and sustained in a real-world non-VA setting. A modified-REP implementation framework may be an appropriate foundational step for other clinical programs seeking to harness protocolized adaptation in mentored dissemination activities. PMID:26804896

  11. A Sequenced Instructional Program in Physical Education for the Handicapped, Phase III. Producing and Disseminating Demonstration Packages. Final Report.

    ERIC Educational Resources Information Center

    Carr, Dorothy B.; Avance, Lyonel D.

    Presented is a sequenced instructional program in physical education which constitutes the third of a three-phase, 4-year project, funded by Title III, for handicapped children, preschool through high school levels, in the Los Angeles Unified School District. Described are the project setting and the following accomplishments: a curriculum guide…

  12. Distilling Common History and Practice Elements to Inform Dissemination: Hanf-Model BPT Programs as an Example

    PubMed Central

    Kaehler, Laura A.; Jacobs, Mary; Jones, Deborah J.

    2016-01-01

    There is a shift in evidence-based practice toward an understanding of the treatment elements that characterize empirically-supported interventions in general and the core components of specific approaches in particular. The evidence-base for Behavioral Parent Training (BPT), the standard of care for early-onset disruptive behavior disorders (Oppositional Defiant Disorder and Conduct Disorder), which frequently co-occur with Attention Deficit Hyperactivity Disorder, is well-established; yet, an ahistorical, program-specific lens tells little regarding how leaders, including Constance Hanf at the University of Oregon, shaped the common practice elements of contemporary evidence-based BPT. Accordingly, this review summarizes the formative work of Hanf, as well as the core elements, evolution, and extensions of her work, represented in Community Parent Education (COPE; Cunningham, Bremner, & Boyle, 1995; Cunningham, Bremner, Secord, & Harrison, 2009), Defiant Children (DC; Barkley 1987; Barkley, 2013), Helping the Noncompliant Child (HNC; Forehand & McMahon, 1981; McMahon & Forehand, 2003), Parent-Child Interaction Therapy (PCIT; Eyberg, & Robinson, 1982; Eyberg, 1988; Eyberg & Funderburk, 2011), and the Incredible Years (IY; Webster-Stratton, 1981; 1982; 2008). Our goal is not to provide an exhaustive review of the evidence-base for the Hanf-Model programs; rather, our intention is to provide a template of sorts from which agencies and clinicians can make informed choices about how and why they are using one program versus another, as well as how to make inform flexible use one program or combination of practice elements across programs, to best meet the needs of child clients and their families. Clinical implications and directions for future work are discussed. PMID:27389606

  13. 34 CFR 75.192 - Dissemination.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of the Secretary, Department of Education DIRECT GRANT PROGRAMS How To Apply for a Grant Development of Curricula Or Instructional Materials § 75.192 Dissemination. If an applicant proposes to publish and disseminate curricula or instructional materials under a grant, the applicant shall include an...

  14. 34 CFR 75.192 - Dissemination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of the Secretary, Department of Education DIRECT GRANT PROGRAMS How To Apply for a Grant Development of Curricula Or Instructional Materials § 75.192 Dissemination. If an applicant proposes to publish and disseminate curricula or instructional materials under a grant, the applicant shall include an...

  15. 34 CFR 75.192 - Dissemination.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... of the Secretary, Department of Education DIRECT GRANT PROGRAMS How To Apply for a Grant Development of Curricula Or Instructional Materials § 75.192 Dissemination. If an applicant proposes to publish and disseminate curricula or instructional materials under a grant, the applicant shall include an...

  16. Federal Mechanisms to Support Intervention Dissemination

    ERIC Educational Resources Information Center

    Diana, Augusto; Bennett, Nicole

    2015-01-01

    This paper examines federal mechanisms that support program developers and researchers in disseminating effective interventions for public benefit. The purpose of this paper is not to discuss the dissemination of intervention research (i.e., how to inform stakeholders about research findings), nor is it intended to discuss the research of…

  17. Federal Mechanisms to Support Intervention Dissemination

    ERIC Educational Resources Information Center

    Diana, Augusto; Bennett, Nicole

    2015-01-01

    This paper examines federal mechanisms that support program developers and researchers in disseminating effective interventions for public benefit. The purpose of this paper is not to discuss the dissemination of intervention research (i.e., how to inform stakeholders about research findings), nor is it intended to discuss the research of…

  18. 14 CFR 1203.303 - Dissemination considerations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Dissemination considerations. 1203.303 Section 1203.303 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Classification Principles and Considerations § 1203.303 Dissemination considerations. The...

  19. 14 CFR 1203.303 - Dissemination considerations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Dissemination considerations. 1203.303 Section 1203.303 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Classification Principles and Considerations § 1203.303 Dissemination considerations. The...

  20. 14 CFR 1203.303 - Dissemination considerations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Dissemination considerations. 1203.303 Section 1203.303 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Classification Principles and Considerations § 1203.303 Dissemination considerations. The...

  1. 14 CFR 1203.303 - Dissemination considerations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Dissemination considerations. 1203.303... PROGRAM Classification Principles and Considerations § 1203.303 Dissemination considerations. The degree... effective security control impractical are considerations during the classification process. These...

  2. CRACOW CLEAN FOSSIL FUELS AND ENERGY EFFICIENCY PROGRAM. PROGRESS REPORT, OCTOBER 1998

    SciTech Connect

    PIERCE,B.

    1998-10-01

    Since 1990 the US Department of Energy has been involved in a program aimed at reducing air pollution caused by small, coal-fired sources in Poland. The program focuses on the city of Cracow and is designed so that results will be applicable and extendable to the entire region. This report serves both as a review of the progress which has been made to date in achieving the program objectives and a summary of work still in progress.

  3. Disseminated histoplasmosis (image)

    MedlinePlus

    Histoplasmosis is a fungal infection caused by inhaling dust from spore-infected bird droppings. In the disseminated ... fairly high for people with untreated widespread (disseminated) histoplasmosis, but is reduced significantly with treatment.

  4. Beneficial uses program. Progress report ending December 31, 1979

    SciTech Connect

    1980-06-01

    Progress is reported in research on uses of irradiated sewage sludge, particularly as a cattle feed supplement and commercial fertilizer additive, on potential sites for irradiator demonstration plants, and on the inactivation of enteric bacteria by radiation treatment. (LCL)

  5. PATHWAYS TO PROGRESS, A RESEARCH MONOGRAPH FROM OHIO'S PROGRAMS

    ERIC Educational Resources Information Center

    KOLB, DAVID A.

    THE EFFECT OF A TRAINING PROGRAM IN ACHIEVEMENT MOTIVATION ON THE OF EDUCATION FOR THE ACADEMICALLY TALENTED STUDENT. AMONG PRESENTED. TWENTY BOYS WITH IQ'S ABOVE 120 AND SCHOOL GRADES BELOW C RECEIVED THE TRAINING PROGRAM IN ADDITION TO AN ACADEMIC SUMMER SCHOOL PROGRAM. THEY WERE COMPARED TO A CONTROL GROUP OF 37 SIMILAR BOYS WHO RECEIVED ONLY…

  6. PATHWAYS TO PROGRESS, A RESEARCH MONOGRAPH FROM OHIO'S PROGRAMS

    ERIC Educational Resources Information Center

    KOLB, DAVID A.

    THE EFFECT OF A TRAINING PROGRAM IN ACHIEVEMENT MOTIVATION ON THE OF EDUCATION FOR THE ACADEMICALLY TALENTED STUDENT. AMONG PRESENTED. TWENTY BOYS WITH IQ'S ABOVE 120 AND SCHOOL GRADES BELOW C RECEIVED THE TRAINING PROGRAM IN ADDITION TO AN ACADEMIC SUMMER SCHOOL PROGRAM. THEY WERE COMPARED TO A CONTROL GROUP OF 37 SIMILAR BOYS WHO RECEIVED ONLY…

  7. LWR Core Materials Program: progress in 1983-1984

    SciTech Connect

    Franklin, D.G.; Gehl, S.M.; Machiels, A.J.; Santucci, J.

    1985-10-01

    The years 1983 and 1984 marked the completion of the power reactor extended-burnup demonstrations, several multinational Ramp programs, the prerelease version of the ESCORE fuel performance code, and the BWR channel extended-life program. Research results gathered under the overall program showed an improvement in core component reliability and an increase in nuclear fuel burnup.

  8. Distilling Common History and Practice Elements to Inform Dissemination: Hanf-Model BPT Programs as an Example.

    PubMed

    Kaehler, Laura A; Jacobs, Mary; Jones, Deborah J

    2016-09-01

    There is a shift in evidence-based practice toward an understanding of the treatment elements that characterize empirically supported interventions in general and the core components of specific approaches in particular. The evidence base for behavioral parent training (BPT) and the standard of care for early-onset disruptive behavior disorders (oppositional defiant disorder and conduct disorder), which frequently co-occur with attention deficit hyperactivity disorder, are well established, yet an ahistorical, program-specific lens tells little regarding how leaders, University of Oregon Medical School, shaped the common practice elements of contemporary evidence-based BPT. Accordingly, this review summarizes the formative work of Hanf, as well as the core elements, evolution, and extensions of her work, represented in Community Parent Education (COPE; (Cunningham et al. in J Child Psychol Psychiatry 36:1141-1159, 1995; Cunningham et al. in COPE, the community parent education program: large group community-based workshops for parents of 3- to 18-year-olds, COPE Works, Hamilton, 2009), Defiant Children (DC; (Barkley in Defiant children: a clinician's manual for assessment and parent training, Guilford Press, New York, 1987; Barkley in Defiant children: a clinician's manual for assessment and parent training, Guilford Press, New York, 2013), Helping the Noncompliant Child (HNC; Forehand and McMahon in Helping the noncompliant child: a clinician's guide to parent training, Guilford Press, New York, 1981; McMahon and Forehand in Helping the noncompliant child: family-based treatment for oppositional behavior, 2nd ed., Guilford Press, New York, 2003), Parent-child interaction therapy (PCIT; Eyberg and Robinson in J Clin Child Adolesc Psychol 11:130-137, 1982. doi:10.1080/15374418209533076; Eyberg in Child Fam Behav Ther 10:33-46, 1988; Eyberg and Funderburk in Parent-child interaction therapy protocol, PCIT International, Gainesville, 2011), and the Incredible Years

  9. Dissemination Activities Report

    ERIC Educational Resources Information Center

    Barclay, Hanna; Batatia, Hudj; Bauters, Merja; Ben Ami, Zvi; Drachman, Raul; Flouris, Giorgos; Jadin, Tanja; Jalonen, Satu; Karlgren, Klas; Karpati, Andrea; Kotzinos, Dimitris; Lakkala, Minna; Lallimo, Jiri; Moen, Anne; Nygard, Kathrine; Paavola, Sami; Padiglia, Sheila; Scapolla, Marina; Sins, Patrick; Vasileva, Tania

    2008-01-01

    In the first 24 months of the project, KP-Lab members were highly dedicated to dissemination and were engaged in various dissemination activities that contributed to the prime objective of the KP-Lab dissemination efforts which is "to make the project widely known to a variety of prospective users and, at a later stage, to promote the…

  10. Biofuels Feedstock Development Program annual progress report for 1991

    SciTech Connect

    Wright, L.L.; Cushman, J.H.; Ehrenshaft, A.R.; McLaughlin, S.B.; McNabb, W.A.; Ranney, J.W.; Tuskan, G.A.; Turhollow, A.F.

    1992-12-01

    This report provides an overview of the ongoing research funded in 1991 by the Department of Energy`s Biofuels Feedstock Development Program (BFDP). The BFDP is managed by the Environmental Sciences Division of the Oak Ridge National Laboratory and encompasses the work formerly funded by the Short Rotation Woody Crops Program and the Herbaceous Energy Crops Program. The combined program includes crop development research on both woody and herbaceous energy crop species, cross-cutting energy and environmental analysis and integration, and information management activities. Brief summaries of 26 different program activities are included in the report.

  11. Biofuels Feedstock Development Program annual progress report for 1991

    SciTech Connect

    Wright, L.L.; Cushman, J.H.; Ehrenshaft, A.R.; McLaughlin, S.B.; McNabb, W.A.; Ranney, J.W.; Tuskan, G.A.; Turhollow, A.F.

    1992-12-01

    This report provides an overview of the ongoing research funded in 1991 by the Department of Energy's Biofuels Feedstock Development Program (BFDP). The BFDP is managed by the Environmental Sciences Division of the Oak Ridge National Laboratory and encompasses the work formerly funded by the Short Rotation Woody Crops Program and the Herbaceous Energy Crops Program. The combined program includes crop development research on both woody and herbaceous energy crop species, cross-cutting energy and environmental analysis and integration, and information management activities. Brief summaries of 26 different program activities are included in the report.

  12. Environmentally Sensitive Areas Surveys Program threatened and endangered species survey: Progress report. Environmental Restoration Program

    SciTech Connect

    King, A.L.; Awl, D.J.; Gabrielsen, C.A.

    1994-09-01

    The Endangered Species Act (originally passed in 1973) is a Federal statute that protects both animal and plant species. The Endangered Species Act identifies species which are, without careful management, in danger of becoming extinct and species that are considered threatened. Along with the designation of threatened or endangered, the Endangered Species Act provides for the identification of appropriate habitat for these species. Since 1993, the United States Department of Energy`s (DOE) Environmental Restoration (ER) Program has supported a program to survey the Oak Ridge Reservation (ORR) for threatened and endangered species. The Environmentally Sensitive Areas Surveys Program initiated vascular plant surveys during fiscal year 1993 and vertebrate animal surveys during fiscal year 1994 to determine the baseline condition of threatened and endangered species on the ORR at the present time. Data collected during these surveys are currently aiding Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Remedial Investigations on the ORR. They also provide data for ER and Waste Management decision documents, ensure that decisions have technical and legal defensibility, provide a baseline for ensuring compliance with principal legal requirements and will increase public confidence in DOE`s adherence to all related environmental resources rules, laws, regulations, and instructions. This report discusses the progress to date of the threatened and endangered species surveys of the ORR.

  13. Progress Twining Program at Shibaura Institute of Technology

    NASA Astrophysics Data System (ADS)

    Komeda, Takashi

    The Shibaura Institute of Technology (SIT) conducts two Twinning Programs. One is Malaysian Twinning Program, which is conducted in cooperation with 15 Japanese universities, and has SIT as its organizing member. The other is Hybrid Twinning Program, which is conducted with partner foreign universities, and is a graduate study program combining Masters and Doctoral programs. Two important reasons for conducting these twinning programs are to increase the number of foreign students studying in Japan and to promote friendly relations with various Asian countries. Twinning program is effective in enrolling students early and in lowering the cost of foreign study. Japanese students benefit too from good influence of interaction with students having a different culture and customs.

  14. Head Start Program Performance Measures. Second Progress Report. Head Start Research.

    ERIC Educational Resources Information Center

    Westat, Inc., Rockville, MD.

    In 1995, Head Start developed performance measures to promote accountability through the assessment of program quality and outcomes. This report is the Head Start program's second progress report on its self-assessment using the Program Performance Measures. The measures are grouped under the five objectives of Head Start: (1) enhance children's…

  15. Annual Progress Report, June 1, 1969-June 1, 1970. Colorado Migrant Health Program.

    ERIC Educational Resources Information Center

    Colorado State Dept. of Health, Denver.

    Narrative and statistical data on the Colorado Migrant Health Program are presented in this 1969-70 annual progress report. The objectives of the program were to develop, augment, and improve health care services to migrant agricultural workers and their families; to develop, expand, and improve existing programs; and to establish and maintain…

  16. First Progress Report on the Head Start Program Performance Measures. Head Start Research.

    ERIC Educational Resources Information Center

    Caliber Associates, Fairfax, VA.

    In 1995, Head Start developed performance measures to promote accountability through the assessment of program quality and outcomes. This report is the Head Start program's first progress report on its self-assessment using the evolving Program Performance Measures. These measures were developed using ideas from the broad community of people…

  17. Effectiveness and Cost-effectiveness of School-based Dissemination Strategies of an Internet-based Program for the Prevention and Early Intervention in Eating Disorders: A Randomized Trial.

    PubMed

    Moessner, Markus; Minarik, Carla; Ozer, Fikret; Bauer, Stephanie

    2016-04-01

    Only little is known about costs and effects (i.e., success) of dissemination strategies, although cost-effective dissemination strategies are crucial for the transfer of interventions into routine care. This study investigates the effects and cost-effectiveness of five school-based dissemination strategies for an Internet-based intervention for the prevention and early intervention of eating disorders. Three-hundred ninety-five schools were randomly assigned to one of five dissemination strategies. Strategies varied with respect to intensity from only sending advertisement materials and asking the school to distribute them among students to organizing presentations and workshops at schools. Effects were defined as the number of page visits, the number of screenings conducted, and the number of registrations to the Internet-based intervention. More expensive strategies proved to be more cost-effective. Cost per page visit ranged from 2.83€ (introductory presentation plus workshop) to 20.37€ (dissemination by student representatives/peers). Costs per screening ranged from 3.30€ (introductory presentation plus workshop) to 75.66€ (dissemination by student representatives/peers), and costs per registration ranged from 6.86€ (introductory presentation plus workshop) to 431.10€ (advertisement materials only). Dissemination of an Internet-based intervention for prevention and early intervention is challenging and expensive. More intense, expensive strategies with personal contact proved to be more cost-effective. The combination of an introductory presentation on eating disorders and a workshop in the high school was most effective and had the best cost-effectiveness ratio. The sole distribution of advertisement materials attracted hardly any participants to the Internet-based program.

  18. F-35 Joint Strike Fighter: Preliminary Observations on Program Progress

    DTIC Science & Technology

    2016-03-23

    Costs Increase Near-Term Funding Needs DOD does not currently plan to manage Block 4 as a separate program with its own acquisition program...comingled. Therefore, it will be difficult for Congress to hold DOD accountable for achieving its cost , schedule, and performance requirements...program has made a number of changes affecting the planned quantities and associated costs .2 According to current projections, the U.S. portion of the

  19. 2007 Annual Progress Report - DOE Hydrogen Program (CD-Rom)

    SciTech Connect

    2007-10-01

    This report summarizes the hydrogen and fuel cell R&D activities and accomplishments in FY2007 for the DOE Hydrogen Program, including the Hydrogen, Fuel Cells, and Infrastructure Technologies Program and hydrogen-related work in the Offices of Science; Fossil Energy; and Nuclear Energy, Science, and Technology. It includes reports on all of the research projects funded by the DOE Hydrogen Program between October 2006 and September 2007.

  20. Advanced Industrial Materials Program. Annual progress report, FY 1993

    SciTech Connect

    Stooksbury, F.

    1994-06-01

    Mission of the AIM program is to commercialize new/improved materials and materials processing methods that will improve energy efficiency, productivity, and competitiveness. Program investigators in the DOE national laboratories are working with about 100 companies, including 15 partners in CRDAs. Work is being done on intermetallic alloys, ceramic composites, metal composites, polymers, engineered porous materials, and surface modification. The program supports other efforts in the Office of Industrial Technologies to assist the energy-consuming process industries. The aim of the AIM program is to bring materials from basic research to industrial application to strengthen the competitive position of US industry and save energy.

  1. Effective dissemination strategies.

    PubMed

    Scullion, Philip A

    2002-01-01

    Dissemination of research findings or other key messages is increasingly acknowledged as a vital yet complex process. In this paper, Philip Scullion sets out to explore and disentangle some of these complexities, examine examples of successful dissemination strategies and provide valuable insights. It is argued that the process of dissemination needs to be afforded greater emphasis by project-funding bodies, research supervisors, researchers, and those responsible for implementing changes in clinical practice. Important initiatives are acknowledged before the concept of dissemination is explored. The source, message, medium and target groups, all key elements in the dissemination process, are then examined. It is argued that dissemination needs to be carefully considered at the design stage of research projects in relation to each of these elements. This paper concludes that the current commitment to research and evidence-based practice will have limited impact on patient care until a similar commitment to dissemination is evident at both corporate and individual levels.

  2. Semiannual progress report for the Idaho Geothermal Program, April 1-September 30, 1981

    SciTech Connect

    Parker, J.T.

    1982-01-01

    Modifications incorporated in the 5-MW Pilot Power Plant at Raft River Geothermal Test Site, system operational testing and maintenance activities at that plant, and the water treatment program's corrosion studies are summarized. Progress is reported on performance tests of the ORNL condenser and the direct-contact heat exchanger in the Prototype Power Plant. Production-injection tests associated with pump installation in monitor wells at Raft River are reported. Case studies conducted and publications prepared for the program of low-to moderate-temperature hydrothermal resource development are also reported. Monitoring activities and studies of the environmental program at Raft River are described and two new areas of research under the Environmental Support Injection Research Program: pressure monitoring, and dispersion studies. Progress of three successful proposers under the User-Coupled Confirmation Drilling Program is summarized. A program to encourage use of geothermal energy at Federal facilities was developed and initiated. Investigation of direct use of hydrothermal energy is reported. Progress is reported on the marketing Assistance Program, through which technical information and assistance are provided to potential users and developers of geothermal resources. Also reported is progress on DOE's Program Opportunity Notice (PON) Program demonstration projects and the Program Research and Development Announcement (PRDA) Program study projects.

  3. Progress Report on ELSP Program, 1979-80.

    ERIC Educational Resources Information Center

    Institute for Services to Education, Inc., Washington, DC.

    Implementation of the Entry Level Skills Program (ELSP) during 1979-80 at Huston-Tillotson College and Wiley College, both historically black institutions in Texas, is described. The ELSP, which is a developmental program for freshman students who have not acquired the full range or level of cognitive skills needed for college, is part of the…

  4. 2009 Annual Progress Report: DOE Hydrogen Program, November 2009 (Book)

    SciTech Connect

    Not Available

    2009-11-01

    This report summarizes the hydrogen and fuel cell R&D activities and accomplishments of the DOE Hydrogen Program for FY2009. It covers the program areas of hydrogen production and delivery; fuel cells; manufacturing; technology validation; safety, codes and standards; education; and systems analysis.

  5. Literacy Education and Families: A Program and Its Progress.

    ERIC Educational Resources Information Center

    Gelfer, Jeff; Higgins, Kyle; Perkins, Peggy

    2001-01-01

    Describes the development, implementation, and evaluation of Project Literacy Education and Families (LEAF), a family literacy program that provides experiences for parents to develop their skills and confidence that will enable them to see possibilities instead of limitations. Details four Program components: adult literacy, early childhood…

  6. Developing Healthy Adolescents--A Progressive Health Care Partnership Program.

    ERIC Educational Resources Information Center

    Griesemer, Bernard A.; Hough, David L.

    1993-01-01

    A 1991 partnership coupling Southwest Missouri State University with Saint John's Regional Health Center spawned the Midwest Sports Medicine Center, originally designed to treat orthopedic injuries. Soon the center developed major educational initiatives, including SportsPACE, a program integrating health care programs into the secondary core…

  7. Developing Healthy Adolescents--A Progressive Health Care Partnership Program.

    ERIC Educational Resources Information Center

    Griesemer, Bernard A.; Hough, David L.

    1993-01-01

    A 1991 partnership coupling Southwest Missouri State University with Saint John's Regional Health Center spawned the Midwest Sports Medicine Center, originally designed to treat orthopedic injuries. Soon the center developed major educational initiatives, including SportsPACE, a program integrating health care programs into the secondary core…

  8. Nuclear Waste Programs semiannual progress report, April--September 1992

    SciTech Connect

    Bates, J.K.; Bradley, C.R.; Buck, E.C.

    1994-05-01

    This document reports on the work done by the Nuclear Waste Programs of the Chemical Technology Division (CMT), Argonne National Laboratory, in the period April--September 1992. In these programs, studies are underway on the performance of waste glass and spent fuel in projected nuclear repository conditions to provide input to the licensing of the nation`s high-level waste repositories.

  9. Space nuclear safety program: Progress report, July--September 1987

    SciTech Connect

    George, T.G.

    1989-02-01

    This quarterly report describes studies related to the use of /sup 238/PuO/sub 2/ in radioisotope power systems, carried out for the Office of Special Nuclear Projects of the US Department of Energy by Los Alamos National Laboratory. The studies discussed are ongoing; the results and conclusions described may change as the work progresses. 20 figs., 4 tabs.

  10. Fossil Energy Program semiannual progress report, April 1990-- September 1990

    SciTech Connect

    Judkins, R.R.

    1991-09-01

    This report covers progress made during the period April 1, 1990, through September 30, 1990, for research and development projects that contribute to the advancement of various fossil energy technologies. Topics discussed include: ceramics and composite materials R&D, new alloys, corrosion and erosion research, coal conversion development, mild gasification. (VC)

  11. Fossil Energy Program semiannual progress report, April 1990-- September 1990

    SciTech Connect

    Judkins, R.R.

    1991-09-01

    This report covers progress made during the period April 1, 1990, through September 30, 1990, for research and development projects that contribute to the advancement of various fossil energy technologies. Topics discussed include: ceramics and composite materials R D, new alloys, corrosion and erosion research, coal conversion development, mild gasification. (VC)

  12. Research program in elementary-particle theory, 1983. Progress report

    SciTech Connect

    Sudarshan, E C.G.; Ne'eman, Y

    1983-08-01

    Progress is reviewed on the following topics: physics of ultra high energies and cosmology; phenomenology of particle physics; quantum field theory, supersymmetry and models of particles; and geometric formulations and algebraic models. Recent DOE reports resulting from the contract are listed. (WHK)

  13. Beneficial uses program. Progress report, period ending March 31, 1980

    SciTech Connect

    Not Available

    1980-08-01

    Progress is reported on dried sewage sludge irradiation, on irradiated sludge use as cattle feed, the inactivation of enteric organisms, the use of irradiation for citrus fruit disinfestation, and the effects of sludge addition on herbicide behavior in soils under laboratory conditions. (LCL)

  14. Space Nuclear Safety Program: Progress report, January-March 1987

    SciTech Connect

    Lewin, R.; George, T.G.

    1988-07-01

    This quarterly report describes studies related to the use of /sup 238/PuO/sub 2/ in radioisotope power systems, which were carried out for the Office of Special Nuclear Projects of the US Department of Energy by Los Alamos National Laboratory. Most of the studies discussed are ongoing; the results and conclusions described may change as the work progresses.

  15. Space Nuclear Safety Program. Progress report, August 1984

    SciTech Connect

    George, T.G.

    1985-11-01

    This technical monthly report covers studies related to the use of /sup 238/PuO/sub 2/ in radioisotope power systems carried out for the Office of Special Nuclear Projects of the US Department of Energy by Los Alamos National Laboratory. Most of the studies discussed are ongoing; the results and conclusions described may change as the work progresses. 41 figs.

  16. Space nuclear safety program. Progress report, October-December 1984

    SciTech Connect

    George, T.G.

    1986-05-01

    This quarterly report covers studies related to the use of /sup 238/PuO/sub 2/ in radioisotope power systems carried out for the Office of Special Nuclear Projects of the US Department of Energy by Los Alamos National Laboratory. Most of the studies discussed are ongoing; the results and conclusions described may change as the work progresses.

  17. Los Alamos National Laboratory Science Education Programs. Quarterly progress report, April 1--June 30, 1995

    SciTech Connect

    Gill, D.

    1995-09-01

    This report is quarterly progress report on the Los Alamos National Laboratory Science Education Programs. Included in the report are dicussions on teacher and faculty enhancement, curriculum improvement, student support, educational technology, and institutional improvement.

  18. Science team participation in the ARM program. Progress report, October 31, 1992--November 1, 1993

    SciTech Connect

    Cess, R.D.

    1993-11-01

    This progress report discusses the Science Team participation in the Atmospheric Radiation Measurement (ARM) Program for the period of October 31, 1992 to November 1, 1993. This report summarized the research accomplishments of six papers.

  19. FY2004 Progress Summary and FY2005 Program Plan Statement of Work and Deliverables

    SciTech Connect

    Meier, W; Bibeau, C

    2006-01-23

    FY2004 progress summary and FY2005 program plan statement of work and deliverables for development of high average power diode-pumped solid state lasers, and complementary technologies for applications in energy and defense.

  20. Waste Management Program. Technical progress report, October-December 1982

    SciTech Connect

    1983-07-01

    This quarterly report provides current information on operations and development programs for the management of radioactive wastes from operation of the Savannah River Plant and offplant participants. The studies on environmental and safety assessments, in situ storage or disposal, waste from development and characterization, process and equipment development, and low-level waste management are a part of the Long-Term Waste Management Technology Program. The following studies are reported for the SR Interim Waste Operations Program: surveillance and maintenance, waste concentration, low-level effluent waste, tank replacement/waste transfer, and solid waste storage and related activities.

  1. Waste Management Program. Technical progress report, Aporil-June 1983

    SciTech Connect

    1984-02-01

    This quarterly report provides current information on operations and development programs for the management of radioactive wastes from operation of the Savannah River Plant. The studies on environmental and safety assessments, process and equipment development, TRU waste, and low-level waste are a part of the Long-Term Waste Management Technology Program. The following studies are reported for the SR Interim Waste Operations Program: surveillance and maintenance, waste concentration, low-level effluent waste, tank replacement/waste transfer, and solid waste storage and related activities.

  2. Heavy Vehicle Propulsion Materials Program: Progress and Highlights

    SciTech Connect

    D. Ray Johnson; Sidney Diamond

    2000-06-19

    The Heavy Vehicle Propulsion Materials Program was begun in 1997 to support the enabling materials needs of the DOE Office of Heavy Vehicle Technologies (OHVT). The technical agenda for the program grew out of the technology roadmap for the OHVT and includes efforts in materials for: fuel systems, exhaust aftertreatment, valve train, air handling, structural components, electrochemical propulsion, natural gas storage, and thermal management. A five-year program plan was written in early 2000, following a stakeholders workshop. The technical issues and planned and ongoing projects are discussed. Brief summaries of several technical highlights are given.

  3. Waste Management Program. Technical progress report, July-December, 1984

    SciTech Connect

    1986-10-01

    This report provides information on operations and development programs for the management of radioactive wastes from operation of the Savannah River Plant and offplant participants. The studies on environmental and safety assessments, other support, in situ storage or disposal, waste form development and characterization, process and equipment development, and the Defense Waste Processing Facility are a part of the Long-Term Waste Management Technology Program. The following studies are reported for the SR Interim Waste Operations: tank farm operation, inspection program, burial ground operations, and waste transfer/tank replacement.

  4. Semiannual progress report for the Idaho Geothermal Program, October 1, 1979-March 31, 1980

    SciTech Connect

    Ihrig, R.R.

    1980-07-01

    Progress is reported for the Idaho Geothermal program between October 1, 1979 and March 31, 1980. Progress on the 5-MW Pilot Power Plant at the Raft River Geothermal Test Site is summarized including construction, steady-state and transient analyses by computer modeling, the geothermal water treatment program, and additional experimental and theoretical work on direct contact heat exchangers. Asbestos-cement pipe failures in the geothermal fluid supply and injection system are also summarized. The successful automatic control-mode testing of the Prototype Power Plant is reported. A continuing direct applications experiment in aquaculture is outlined, and a proposal to study various ramifications of irrigating agricultural and range lands with spent geothermal fluid is described briefly. Also outlined is the second experimental hydraulic fracture treatment of a geothermal well at Raft River as part of the National Well Stimulation Program. The improvements to the Raft River site facilities are described, and progress in providing technical information and assistance in the Outreach, or User Assistance program presented. Also presented is a new DOE program, the User Coupled Confirmation Drilling Program, which is intended to reduce the financial risk of hydrothermal reservoir exploration by the private sector. Progress reports are also included on DOE's Program Opportunity Notice (PON) Program demonstration projects and Program Research and Development Announcement (PRDA) Program study projects.

  5. Student Experiences of High-Stakes Testing for Progression in One Undergraduate Nursing Program

    ERIC Educational Resources Information Center

    McClenny, Tammy

    2016-01-01

    High-stakes testing in undergraduate nursing education are those assessments used to make critical decisions for student progression and graduation. The purpose of this study was to explore the different ways students experience multiple high-stakes tests for progression in one undergraduate BSN program. Research participants were prelicensure…

  6. The Indian Education Act of 1972. Report of Progress for the Third Year of the Program.

    ERIC Educational Resources Information Center

    Office of Education (DHEW), Washington, DC. Office of Indian Education.

    Program implementation under the American Indian Education Act of 1972 (IEA) is evaluated in this 1975 progress report via narrative and tabular data. Presenting an executive summary and reviews of the first and second years of progress, this third year evaluation focuses upon: the extent to which Indian children have received IEA services; IEA…

  7. Student Experiences of High-Stakes Testing for Progression in One Undergraduate Nursing Program

    ERIC Educational Resources Information Center

    McClenny, Tammy

    2016-01-01

    High-stakes testing in undergraduate nursing education are those assessments used to make critical decisions for student progression and graduation. The purpose of this study was to explore the different ways students experience multiple high-stakes tests for progression in one undergraduate BSN program. Research participants were prelicensure…

  8. Underground Energy Storage Program: 1981 annual report. Volume I. Progress summary

    SciTech Connect

    Kannberg, L.D.

    1982-06-01

    This is the 1981 annual report for the Underground Energy Storage Program administered by the Pacific Northwest Laboratory for the US Department of Energy. The two-volume document describes all of the major research funded under this program during the period March 1981 to March 1982. Volume I summarizes the activities and notable progress toward program objectives in both Seasonal Thermal Energy Storage (STES) and Compressed Air Energy Storage (CAES). Major changes in program emphasis and structure are also documented.

  9. Fast reactor safety program. Progress report, January-March 1980

    SciTech Connect

    1980-05-01

    The goal of the DOE LMFBR Safety Program is to provide a technology base fully responsive to safety considerations in the design, evaluation, licensing, and economic optimization of LMFBRs for electrical power generation. A strategy is presented that divides safety technology development into seven program elements, which have been used as the basis for the Work Breakdown Structure (WBS) for the Program. These elements include four lines of assurance (LOAs) involving core-related safety considerations, an element supporting non-core-related plant safety considerations, a safety R and D integration element, and an element for the development of test facilities and equipment to be used in Program experiments: LOA-1 (prevent accidents); LOA-2 (limit core damage); LOA-3 (maintain containment integrity); LOA-4 (attenuate radiological consequences); plant considerations; R and D integration; and facility development.

  10. Space nuclear safety program, April 1983. Progress report

    SciTech Connect

    Bronisz, S.E.

    1983-10-01

    This program related to the use of plutonium-238 dioxide in radioisotope power systems. Reported in this document is a phosphorus effects experiment and a compatibility test for the General-Purpose Heat Source. (DLC)

  11. Advanced Industrial Materials (AIM) Program: Annual progress report FY 1995

    SciTech Connect

    1996-04-01

    In many ways, the Advanced Industrial Materials (AIM) Program underwent a major transformation in Fiscal Year 1995 and these changes have continued to the present. When the Program was established in 1990 as the Advanced Industrial Concepts (AIC) Materials Program, the mission was to conduct applied research and development to bring materials and processing technologies from the knowledge derived from basic research to the maturity required for the end use sectors for commercialization. In 1995, the Office of Industrial Technologies (OIT) made radical changes in structure and procedures. All technology development was directed toward the seven ``Vision Industries`` that use about 80% of industrial energy and generated about 90% of industrial wastes. The mission of AIM has, therefore, changed to ``Support development and commercialization of new or improved materials to improve productivity, product quality, and energy efficiency in the major process industries.`` Though AIM remains essentially a National Laboratory Program, it is essential that each project have industrial partners, including suppliers to, and customers of, the seven industries. Now, well into FY 1996, the transition is nearly complete and the AIM Program remains reasonably healthy and productive, thanks to the superb investigators and Laboratory Program Managers. This Annual Report for FY 1995 contains the technical details of some very remarkable work by the best materials scientists and engineers in the world. Areas covered here are: advanced metals and composites; advanced ceramics and composites; polymers and biobased materials; and new materials and processes.

  12. Progress Report for the Joint Services Electronics Program

    DTIC Science & Technology

    1989-06-30

    NOTATION 17. COSATI CODES 18. SUBJECT TERMS (Continue on reverse if necessary and identify by block number) FIELD GROUP SUB-GROUP 19. ABSTRACT (Continue on...reverse if necessary and identify by block number) This is the third annual progress report of the research conducted at the Coordinated Science...doped films were , eii dc.;crit-ed b , theoret’’-i -1lculations. ’A ith iio adjustable parameters, including lattice, ioniZed impurity, neutral Impurity

  13. Heat Source Technology Program monthly progress report, June 1993

    SciTech Connect

    George, T.G.

    1993-09-01

    This monthly report describes activities performed in support of Cassini fueled-clad production and studies related to the use of {sup 238}PuO{sub 2} in radioisotope power systems carried out for the Office of Special Applications of the US Department of Energy (DOE) by Los Alamos National Laboratory (LANL). Most of the activities described are ongoing; the results and conclusions described may change as the work progresses.

  14. Heat source technology programs. Monthly progress report, March 1995

    SciTech Connect

    Tomlinson, L.J.

    1996-02-01

    This monthly report describes activities performed in support of Cassini fueled-clad production and studies related to the use of {sup 238}PuO{sub 2} in radioisotope power systems carried out for the Office of Special Applications of the US Department of Energy (DOE) by Los Alamos National Laboratory (LANL). Most of the activities described are ongoing; the results and conclusions described may change as the work progresses.

  15. Heat source technology programs: Monthly progress report, March 1994

    SciTech Connect

    George, T.G.

    1994-08-01

    This monthly report describes activities performed in support of Cassini fueled-clad production and studies related to the use of {sup 238}PuO{sub 2} in radioisotope power systems carried out for the Office of Special Applications of the US Department of Energy (DOE) by Los Alamos National Laboratory (LANL). Most of the activities described are ongoing; the results and conclusions described may changes as the work progresses.

  16. Heat Source Technology Program monthly progress report, July 1993

    SciTech Connect

    George, T.G.

    1993-10-01

    This monthly report describes activities performed in support of Cassini fueled-clad production and studies related to the use of {sup 238}PuO{sub 2} in radioisotope power systems carried out for the Office of Special Applications of the US Department of Energy (DOE) by Los Alamos National Laboratory (LANL). Most of the activities described are ongoing; the results and conclusions described may change as the work progresses.

  17. Heat source technology programs: Monthly progress report, April 1994

    SciTech Connect

    George, T.G.

    1994-09-01

    This monthly report describes activities performed in support of Cassini fueled-clad production and studies related to the use of {sup 238}PuO{sub 2} in radioisotope power systems carried out for the Office of Special Applications of the US Department of Energy (DOE) by Los Alamos National Laboratory (LANL). Most of the activities described are ongoing; the results and conclusion described may change as the work progresses.

  18. Monthly progress report Heat Source Technology Programs, April 1995

    SciTech Connect

    George, T.G.

    1996-03-01

    This monthly report describes activities performed in support of Cassini fueled-clad production and studies related to the use of {sup 238}PuO{sub 2} in radioisotope power systems carried out for the Office of Special Applications of the US Department of Energy (DOE) by Los Alamos National Laboratory (LANL). Most of the activities described are ongoing; the results and conclusions described may change as the work progresses.

  19. 10 CFR 602.18 - Dissemination of results.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Dissemination of results. 602.18 Section 602.18 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.18 Dissemination of results. (a) Recipients are encouraged to disseminate research...

  20. 10 CFR 602.18 - Dissemination of results.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Dissemination of results. 602.18 Section 602.18 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.18 Dissemination of results. (a) Recipients are encouraged to disseminate research...

  1. 10 CFR 602.18 - Dissemination of results.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Dissemination of results. 602.18 Section 602.18 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.18 Dissemination of results. (a) Recipients are encouraged to disseminate research...

  2. 10 CFR 602.18 - Dissemination of results.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Dissemination of results. 602.18 Section 602.18 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.18 Dissemination of results. (a) Recipients are encouraged to disseminate research...

  3. Learning Disabilities: Program Evaluation. Progress Report 1980-1981 [and] Learning Disabilities: Program Evaluation. Progress Report 1981-1982.

    ERIC Educational Resources Information Center

    Bersell, Gary L.; Balliet, Tom

    The plan for the evaluation of Janesville, Wisconsin, Public Schools Learning Disabilities Program is presented, along with 1980-1981 and 1981-1982 findings, and supplementary data and forms. The proposed evaluation model, which includes evaluation dimensions, evaluation procedures, and desired outcomes, is presented. The program is reviewed in…

  4. The Human Genome Project and Mental Retardation: An Educational Program. Final Progress Report

    SciTech Connect

    Davis, Sharon

    1999-05-03

    The Arc, a national organization on mental retardation, conducted an educational program for members, many of whom have a family member with a genetic condition causing mental retardation. The project informed members about the Human Genome scientific efforts, conducted training regarding ethical, legal and social implications and involved members in issue discussions. Short reports and fact sheets on genetic and ELSI topics were disseminated to 2,200 of the Arc's leaders across the country and to other interested individuals. Materials produced by the project can e found on the Arc's web site, TheArc.org.

  5. Technology-based dissemination.

    PubMed

    Jennett, P A; Premkumar, K

    1996-01-01

    Health care reform and restructuring, changes in the scope and definitions of 'health', 'health care' and 'health research', along with a continued emphasis on multidisciplinary health promotion and prevention, all indicate the need for information dissemination, exchange and management. Technology can be a tool to help meet this need, as it can help us disseminate, as well as understand the process of dissemination. Rapid advances in, and reduced costs of technology, permit the integration of this tool. This paper provides a definition for dissemination, along with a background and rationale as to why now is the time and place to harness technology to assist with the dissemination process. In addition, it presents well-designed studies on the effective use of technology as an aid to dissemination. Concrete examples of innovative technology that are being tested are also examined. Finally, the challenge and strategies for technology integration are addressed.

  6. NIST Mechanisms for Disseminating Measurements

    PubMed Central

    Gills, T. E.; Dittman, S.; Rumble, J. R.; Brickenkamp, C. S.; Harris, G. L.; Trahey, N. M.

    2001-01-01

    The national responsibilities assigned to the National Bureau of Standards (NBS) early in the last century for providing measurement assistance and service are carried out today by the four programs that comprise the National Institute of Standards and Technology (NIST) Office of Measurement Services (OMS). They are the Calibration Program (CP), the Standard Reference Materials Program (SRMP), the Standard Reference Data Program (SRDP), and the Weights and Measures Program (W&MP). Organized when the U.S. Congress changed the NBS name to NIST, the OMS facilitates access to the measurement and standards activities of NIST laboratories and programs through the dissemination of NIST products, data, and services. A brief historical introduction followed by a perspective of pivotal measurement developments from 1901 to the present and concluding with a look to the future of NIST measurement services in the next decade of the new millennium are presented for each OMS program. PMID:27500025

  7. 2011 Annual Progress Report: DOE Hydrogen and Fuel Cells Program (Book)

    SciTech Connect

    Not Available

    2011-11-01

    In the past year, the DOE Hydrogen and Fuel Cells Program (the Program) made substantial progress toward its goals and objectives. The Program has conducted comprehensive and focused efforts to enable the widespread commercialization of hydrogen and fuel cell technologies in diverse sectors of the economy. With emphasis on applications that will effectively strengthen our nation's energy security and improve our stewardship of the environment, the Program engages in research, development, and demonstration of critical improvements in the technologies. Highlights of the Program's accomplishments can be found in the sub-program chapters of this report.

  8. Remediating minimal progress on teaching programs by adults with severe disabilities in a congregate day setting.

    PubMed

    Parsons, Marsha B; Reid, Dennis H; Towery, Donna; England, Peggy; Darden, Michaela

    2008-01-01

    We evaluated a modified teaching approach for improving the performance of adults with severe disabilities who were making minimal progress on teaching programs in a congregate day setting. An approach for enhancing progress was developed for implementation within the ongoing routine of the adult day setting using resources indigenous to the setting. The teaching approach, based on early intensive teaching programs, involved increasing teaching trials, adding another consequence to the reinforcement component, and reducing distractions. Improved progress accompanied the approach with each of 4 participating adults. Measures of happiness and problem behavior showed no detrimental effect on quality of life. Advantages and disadvantages of the teaching approach are discussed regarding implications for practitioners.

  9. Hazardous Waste Remedial Actions Program annual progress report, FY 1990

    SciTech Connect

    Not Available

    1990-12-01

    The Hazardous Waste Remedial Actions Programs (HAZWRAP), a unit of Martin Marietta Energy Systems, Inc., supports the Department of Energy (DOE) Oak Ridge Operations Office in broadly environmental areas, especially those relating to waste management and environmental restoration. HAZWRAP comprises six program areas, which are supported by central administrative and technical organizations. Existing programs deal with airborne hazardous substances, pollution prevention, remedial actions planning, environmental restoration, technology development, and information and data systems. HAZWRAP's mission to develop, promote, and apply-cost-effective hazardous waste management and environmental technologies to help solve national problems and concerns. HAZWRAP seeks to serve as integrator for hazardous waste and materials management across the federal government. It applies the unique combination of research and development (R D) capabilities, technologies, management expertise, and facilities in the Energy Systems complex to address problems of national importance. 24 figs., 10 tabs.

  10. Progress in sensorimotor rehabilitative physical therapy programs for stroke patients

    PubMed Central

    Chen, Jia-Ching; Shaw, Fu-Zen

    2014-01-01

    Impaired motor and functional activity following stroke often has negative impacts on the patient, the family and society. The available rehabilitation programs for stroke patients are reviewed. Conventional rehabilitation strategies (Bobath, Brunnstrom, proprioception neuromuscular facilitation, motor relearning and function-based principles) are the mainstream tactics in clinical practices. Numerous advanced strategies for sensory-motor functional enhancement, including electrical stimulation, electromyographic biofeedback, constraint-induced movement therapy, robotics-aided systems, virtual reality, intermittent compression, partial body weight supported treadmill training and thermal stimulation, are being developed and incorporated into conventional rehabilitation programs. The concept of combining valuable rehabilitative procedures into “a training package”, based on the patient’s functional status during different recovery phases after stroke is proposed. Integrated sensorimotor rehabilitation programs with appropriate temporal arrangements might provide great functional benefits for stroke patients. PMID:25133141

  11. Advanced Industrial Materials (AIM) program. Annual progress report. FY 1996

    SciTech Connect

    1997-04-01

    The Advanced Industrial Materials (AIM) Program underwent a major transformation in Fiscal Year 1995 and these changes have continued to the present. When the Program was established in 1990 as the Advanced Industrial Concepts (AIC) Materials Program, the mission was to conduct applied research and development to bring materials and processing technologies from the knowledge derived from basic research to the maturity required for the end use sectors for commercialization. In 1995, the Office of Industrial Technologies (OIT) made radical changes in structure and procedures. All technology development was directed toward the seven `Vision Industries` that use about 80% of industrial energy and generated about 90% of industrial wastes. These are: aluminium; chemical; forest products; glass; metal casting; refineries; and steel. OIT is working with these industries, through appropriate organizations, to develop Visions of the desired condition of each industry some 20 or 25 years in the future and then to prepare Road Maps and Implementation Plans to enable them to reach their goals. The mission of AIM has, therefore, changed to `Support development and commercialization of new or improved materials to improve productivity, product quality, and energy efficiency in the major process industries.` Though AIM remains essentially a National Laboratory Program, it is necessary that each project have industrial partners, including suppliers to, and customers of, the seven industries. Now, well into FY 1996, the transition is nearly complete and the AIM Program remains healthy and productive, thanks to the superb investigators and Laboratory Program Managers. Separate abstracts have been indexed into the energy database for articles from this report.

  12. Progress Report on the US Critical Zone Observatory Program

    NASA Astrophysics Data System (ADS)

    Barrera, E. C.

    2014-12-01

    The Critical Zone Observatory (CZO) program supported by the National Science Foundation originated from the recommendation of the Earth Science community published in the National Research Council report "Basic Research Opportunities in Earth Sciences" (2001) to establish natural laboratories to study processes and systems of the Critical Zone - the surface and near-surface environment sustaining nearly all terrestrial life. After a number of critical zone community workshops to develop a science plan, the CZO program was initiated in 2007 with three sites and has now grown to 10 sites and a National Office, which coordinates research, education and outreach activities of the network. Several of the CZO sites are collocated with sites supported by the US Long Term Ecological Research (LTER) and the Long Term Agricultural Research (LTAR) programs, and the National Ecological Observatory Network (NEON). Future collaboration with additional sites of these networks will add to the potential to answer questions in a more comprehensive manner and in a larger regional scale about the critical zone form and function. At the international level, CZOs have been established in many countries and strong collaborations with the US program have been in place for many years. The next step is the development of a coordinated international program of critical zone research. The success of the CZO network of sites can be measured in transformative results that elucidate properties and processes controlling the critical zone and how the critical zone structure, stores and fluxes respond to climate and land use change. This understanding of the critical zone can be used to enhance resilience and sustainability, and restore ecosystem function. Thus, CZO science can address major societal challenges. The US CZO network is a facility open to research of the critical zone community at large. Scientific data and information about the US program are available at www.criticalzone.org.

  13. Progress report of the National Weatherization Assistance Program

    SciTech Connect

    Berry, L.G.; Brown, M.A.; Kinney, L.F.

    1997-09-01

    The National Weatherization Evaluation of the 1989 Program Year and the Metaevaluation of 1996 are described in two ways in this summary document. The text pages summarize the results of the two evaluations conducted by the Oak Ridge National Laboratory. The photographs and explanations illustrate weatherization operations and tactics. An overview and history of the program is provided, followed by the scope of weatherization, metaevaluation methods and results for 1996, national evaluation methods and results for 1989, response to evaluation findings, remaining opportunities, and next steps. Conclusions and significant findings are then given.

  14. Prediction monitoring and evaluation program; a progress report

    USGS Publications Warehouse

    Hunter, R.N.; Derr, J.S.

    1978-01-01

    As part of an attempt to separate useful predictions from inaccurate guesses, we have kept score on earthquake predictions from all sources brought to our attention over the past year and a half. The program was outlined in "Earthquake Prediction;Fact and Fallacy" by Roger N. Hunter (Earthquake Information Bulletin, vol. 8, no. 5, September-October 1976, p. 24-25). The program attracted a great deal of public attention, and, as a result, our files now contain over 2500 predictions from more than 230 different people. 

  15. Geothermal Injection Technology Program: Annual progress report, Fiscal Year 1986

    SciTech Connect

    Not Available

    1987-07-01

    This report summarizes the Geothermal Injection Technology Program major activities in fiscal year 1986. The Idaho Engineering Laboratory (INEL) and the University of Utah Research Institute (UURI) have been conducting injection research and testing for this program, which was initiated in 1983. Activities at the INEL, representative element nodeling of fracture systems based on stochastic analysis, dual permeability modeling of flow in a fractured geothermal reservoir, and dual permeability model - laboratory and FRACSL-validation studies, are presented first, followed by the University of Utah Research Institute tracer development - experimental studies, which includes a brief description of activities planned for FY-1987.

  16. Juvenile Mentoring Program: A Progress Review. Juvenile Justice Bulletin.

    ERIC Educational Resources Information Center

    Novotney, Laurence C.; Mertinko, Elizabeth; Lange, James; Baker, Tara Kelley

    The greatest support offered by the Office of Juvenile Justice and Delinquency Prevention for youth mentoring has been through the Juvenile Mentoring Program (JUMP), which provides one-to-one mentoring for youth at risk of delinquency, gang involvement, educational failure, or dropping out of school. Information on JUMP has been collected through…

  17. 2010/2015 PFOA Stewardship Program - 2014 Annual Progress Reports

    EPA Pesticide Factsheets

    In 2006, EPA and the eight major companies in the industry launched the 2010/15 PFOA Stewardship Program, in which companies committed to reduce global facility emissions and product content of PFOA and related chemicals by 95 percent by 2010, and to work

  18. Progression of Cohort Learning Style during an Intensive Education Program

    ERIC Educational Resources Information Center

    Compton, David A.; Compton, Cynthia M.

    2017-01-01

    The authors describe an intensive graduate program involving compressed classroom preparation followed by a period of experiential activities designed to reinforce and enhance the knowledge base. Beginning with a brief review of the andragogical issues, they describe methods undertaken to track learning styles via the Kolb Learning Styles…

  19. Evaluation of Student Progress in Multicultural Art Programs.

    ERIC Educational Resources Information Center

    Zimmerman, Enid

    Evaluation of student learning and achievement in multicultural art programs should reflect the learning styles of students from diverse ethnic, racial, and class backgrounds. Traditional standardized tests measure factural knowledge and memorization skills never higher order thinking skills. Some authentic assessment measures include exhibitions,…

  20. Hydrothermal Injection Research Program. Annual progress report, FY 1983

    SciTech Connect

    Blackett, R.E.; Kolesar, P.T.; Capuano, R.G.; Sill, W.R.; Allman, D.W.; Hull, L.C.; Large, R.M.; Miller, J.D.; Skiba, P.A.; Downs, W.F.; Koslow, K.N.; McAtee, R.E.; Russell, B.F.

    1983-11-01

    The test program was initiated at the Raft River Geothermal Field in southern Idaho in September of 1982. A series of eight short-term injection and backflow tests followed by a long-term injection test were conducted on one well in the field. Tracers were added during injection and monitored during backflow of the well. The test program was successful, resulting in a unique data set which shows promise as a means to improve understanding of the reservoir characteristics. In December of 1982 an RFP was issued to obtain an industrial partner to obtain follow-on data on the injection/backflow technique in a second field and to study any alternate advanced concepts for injection testing which the industrial community might recommend. Republic Geothermal, Inc. and the East Mesa Geothermal Field were selected for the second test series. Two wells were utilized for testing, and a series of ten tests were conducted in July and August of 1983 aimed principally at further evaluation of the injection/backflow technique. This test program was also successfully completed. This report describes in detail the analysis conducted on the Raft River data, the supporting work at EG and G Idaho and at ESL/UURI, and gives an overview of the objectives and test program at East Mesa.

  1. Space Nuclear Safety Program. Progress report, April 1984

    SciTech Connect

    George, T.G.

    1985-10-01

    This technical monthly report covers studies related to the use of /sup 238/PuO/sub 2/ in radioisotope power systems carried out for the Office of Special Nuclear Projects of the US Department of Energy by Los Alamos National Laboratory. Covered are: general-purpose heat source testing and recovery, and safety technology program (biaxial testing, iridium chemistry).

  2. Progression of Cohort Learning Style during an Intensive Education Program

    ERIC Educational Resources Information Center

    Compton, David A.; Compton, Cynthia M.

    2017-01-01

    The authors describe an intensive graduate program involving compressed classroom preparation followed by a period of experiential activities designed to reinforce and enhance the knowledge base. Beginning with a brief review of the andragogical issues, they describe methods undertaken to track learning styles via the Kolb Learning Styles…

  3. Mining and Reclamation Cooperative Education Program. Progress Report.

    ERIC Educational Resources Information Center

    Barnett, Carl D.

    The exemplary project was the cooperative effort of two schools in the western Kentucky coal fields to field test a program in mining and reclamation technology. Covering the first year of the project, the report describes the problem and scope of the study, the objectives pursued, the methodology, and the results obtained. The goal of the project…

  4. Advanced Industrial Materials (AIM) Program. Annual progress report, FY 1994

    SciTech Connect

    Sorrell, C.A.

    1995-05-01

    The Advanced Industrial Materials Program is a part of the Office of Industrial Technologies (OIT), Energy Efficiency and Renewable Energy in the Department of Energy. The mission of the AIM Program is to conduct applied research, development, and applications engineering work, in partnership with industry, to commercialize new or improved materials and materials processing methods that will improve energy efficiency, productivity, and competitiveness. AIM is responsible for identifying, supporting, and coordinating multidisciplinary projects to solve identified industrial needs and transferring the technology to the industrial sector. Program investigators in the DOE National Laboratories are working closely with approximately 100 companies, including 15 partners in Cooperative Research and Development Agreements. Work is being done in a wide variety of materials technologies, including intermetallic alloys, ceramic composites, metal composites, polymers, engineered porous materials, and surface modification. The Program supports other efforts in the Office of Industrial Technologies to assist the energy consuming process industries, including forest products, glass, steel, aluminum, foundries, chemicals, and refineries. To support OITs {open_quotes}Industries of the Future{close_quotes} initiatives and to improve the relevance of materials research, assessments of materials needs and opportunities in the process industries are being made. These assessments are being used for program planning and priority setting; support of work to satisfy those needs is being provided. Many new materials that have come into the marketplace in recent years, or that will be available for commercial use within a few more years, offer substantial benefits to society. This document contains 28 reports on advanced materials research. Individual reports have been processed separately for entry onto the Department of Energy databases.

  5. Program on Application of Communications Satellites to Educational Development. Progress Report.

    ERIC Educational Resources Information Center

    Morgan, R. P.; Singh, J. P.

    An interdisciplinary program is exploring the educational services which communications satellites may help provide and the synthesis of systems for delivering these services in the United States. From November 1970 to November 1971 substantial progress was made in three primary program categories: needs analysis, communications technology…

  6. Geothermal Drilling and Completion Technology Development Program. Quarterly progress report, October 1980-December 1980

    SciTech Connect

    Kelsey, J.R.

    1981-03-01

    The progress, status, and results of ongoing Research and Development (R and D) within the Geothermal Drilling and Completion Technology Development Program are described. The program emphasizes the development of geothermal drilling hardware, drilling fluids, completion technology, and lost circulation control methods. Advanced drilling systems are also under development.

  7. Geothermal Drilling and Completion Technology Development Program. Quarterly progress report, January 1981-March 1981

    SciTech Connect

    Kelsey, J.R.

    1981-06-01

    The progress, status, and results of ongoing Research and Development (R and D) within the Geothermal Drilling and Completion Technology Development Program are described. The program emphasizes the development of geothermal drilling hardware, drilling fluids, completion technology, and lost circulation control methods as they apply to advanced drilling systems.

  8. The Impact of the Measures of Academic Progress (MAP) Program on Student Reading Achievement

    ERIC Educational Resources Information Center

    Cordray, David S.; Pion, Georgine M.; Brandt, Chris; Molefe, Ayrin

    2013-01-01

    One of the most widely used commercially available systems incorporating benchmark assessment and training in differentiated instruction is the Northwest Evaluation Association's (NWEA) Measures of Academic Progress (MAP) program. The MAP program involves two components: (1) computer-adaptive assessments administered to students three to four…

  9. The Indian Education Act of 1972. Report of Progress for the Second Year of the Program.

    ERIC Educational Resources Information Center

    Office of Education (DHEW), Washington, DC. Office of Indian Education.

    Program implementation under the American Indian Education Act of 1972 (IEA) is evaluated in this progress report via narrative and tabular data relative to the following: (1) Comparative Overview of 1973 and 1974 Title IV-IEA Programs (project funding, entitlement, and eligibility; grants and funding; Indian pupil enrollment; per pupil…

  10. Piloting the AIM Project: Measuring Progress for Program Evaluation and Accountability.

    ERIC Educational Resources Information Center

    Mundie, Karen; Thompson, Debbie; Joyce, Michelle

    The AIM (Assessment, Instruction, Mastery) system is a performance-based assessment that was developed in Oregon. The AIM system was piloted by 83 volunteers and staff from 18 volunteer-based programs to assess the system's usefulness as a means of collecting and aggregating data on student progress in adult literacy and similar programs in…

  11. Development and Preliminary Testing of PROGRESS: A Web-based Education Program for Prostate Cancer Survivors Transitioning from Active Treatment

    PubMed Central

    Miller, Suzanne M.; Hudson, Shawna V.; Hui, Siu-kuen Azor; Diefenbach, Michael A.; Fleisher, Linda; Raivitch, Stephanie; Belton, Tanisha; Roy, Gem; Njoku, Anuli; Scarpato, John; Viterbo, Rosalia; Buyyounouski, Mark; Denlinger, Crystal; Miyamoto, Curtis; Reese, Adam; Baman, Jayson

    2015-01-01

    Purpose This formative research study describes the development and preliminary evaluation of a theory-guided, on-line multimedia psycho-educational program (PROGRESS) designed to facilitate adaptive coping among prostate cancer patients transitioning from treatment into long-term survivorship. Methods Guided by the Cognitive-Social Health Information Processing Model (C-SHIP) and using health communications best practices, we conducted a two phase, qualitative formative research study with early stage prostate cancer patients (n=29) to inform the web program development. Phase 1 included individual (n=5) and group (n=12) interviews to help determine intervention content and interface. Phase 2 employed iterative user/usability testing (n=12) to finalize the intervention. Interview data were independently coded and collectively analyzed to achieve consensus. Results Survivors expressed interest in action-oriented content on: (1) managing treatment side effects; (2) handling body image and co-morbidities related to overweight/obesity; (3) coping with emotional and communication issues; (4) tips to reduce disruptions of daily living activities, and (5) health skills training tools. Patients also desired the use of realistic and diverse survivor images. Conclusions Incorporation of an established theoretical framework, application of multimedia intervention development best practices, and an evidence-based approach to content and format, resulted in a psycho-educational tool that comprehensively addresses survivors' needs in a tailored fashion. Implications for Cancer Survivors The results suggest that an interactive web-based multimedia program is useful for survivors if it covers the key topics of symptom control, emotional well-being, and coping skills training; this tool has the potential to be disseminated and implemented as an adjunct to routine clinical care. PMID:25697335

  12. Fiber Optic Repair and Maintainability (FORM) Program Progresses

    NASA Technical Reports Server (NTRS)

    2005-01-01

    Advanced aircraft will employ fiber-optic interconnection components to transmit information from airframe and propulsion sensors to the flight control computers. Although these optical interconnects have been rigorously tested under laboratory conditions to determine their operating and environmental limits, there is concern as to their repairability and maintainability when placed in actual service. The Fiber Optic Repair and Maintainability (FORM) flight test program will provide data to enable designers to improve these fiber-optic interconnection systems for the next generation of aircraft. FORM is identifying critical problems in installing, maintaining, testing, and repairing fiber-optic interconnection systems in an operational avionics environment. This program is a cooperative Government/industry effort to evaluate optical component acceptability and installation techniques for aircraft.

  13. Pressure vessel burst test program - Progress paper No. 4

    NASA Technical Reports Server (NTRS)

    Cain, Maurice R.; Sharp, Douglas E.

    1993-01-01

    A status report is presented for a program studying the characteristics of the blast waves and fragmentation caused by ruptured gas-filled pressure vessels. Experimental data trends have been derived from 14 burst pressure vessels. Attention is given to energy release in bursting, blast wave and fragmentation behavior, height of burst effects, fragment velocity vs vessel pressure, and comparative blast effects for spherical/composite vs cylindrical/steel pressure vessels.

  14. GSA committees: Progress through service the Annual Program Committee

    USGS Publications Warehouse

    Costa, J.E.

    2007-01-01

    The GSA's Annual Program Committee (APC) is directly responsible for the GSA's meeting and other responsibilities especially before the main event. It decides on the locations, the number and content of the technical sessions, annual membership surveys, hospitality for the guests, field trips and more. In addition, it pays significant attention to creative thinking about geoscience discoveries and directions as well as identify new and emerging areas of earth science. APC is also looking for new ideas, approaches and directions.

  15. Advanced Industrial Materials (AIM) Program annual progress report, FY 1997

    SciTech Connect

    1998-05-01

    The Advanced Industrial Materials (AIM) Program is a part of the Office of Industrial Technologies (OIT), Energy Efficiency and Renewable Energy, US Department of Energy (DOE). The mission of AIM is to support development and commercialization of new or improved materials to improve energy efficiency, productivity, product quality, and reduced waste in the major process industries. OIT has embarked on a fundamentally new way of working with industries--the Industries of the Future (IOF) strategy--concentrating on the major process industries that consume about 90% of the energy and generate about 90% of the waste in the industrial sector. These are the aluminum, chemical, forest products, glass, metalcasting, and steel industries. OIT has encouraged and assisted these industries in developing visions of what they will be like 20 or 30 years into the future, defining the drivers, technology needs, and barriers to realization of their visions. These visions provide a framework for development of technology roadmaps and implementation plans, some of which have been completed. The AIM Program supports IOF by conducting research and development on materials to solve problems identified in the roadmaps. This is done by National Laboratory/industry/university teams with the facilities and expertise needed to develop new and improved materials. Each project in the AIM Program has active industrial participation and support.

  16. Amchitka Radiobiological Program progress report, January 1979-December 1979

    SciTech Connect

    Thornberg, L.D.; Sibley, T.H.; Nakatani, R.E.

    1980-07-01

    The objective of the Amchitka Radiobiological Program for the period 1970-1979 was to determine the extent of radionuclide contamination from world-wide atmospheric fallout and from the detonation of three underground nuclear blasts on Amchitka Island. The objective is achieved, by the collection and radiological analyses of biological and environmental samples and by background radiation measurements. Leakage of radionuclides from the underground sites of the Amchitka nuclear detonations would be suspected if the contamination was significntly greater than would be expected from world fallout. An account of the program from July 1970 to December 1978 has been given in nine previous reports from the Laboratory of Radiation Ecology to the Nevada Operations Office of the US Department of Energy. This report is an account of the program for calendar year 1979. The results of analyses of the samples collected in 1979 lead to the same conclusions as in previous years; i.e., there is no evidence that the radionuclide contamination at Amchitka Island is greater than would be expected from world fallout except for a slight contamination of the Long Shot Mud Pits with tritium.

  17. Recent progress in the Los Alamos KrF Program

    SciTech Connect

    McDonald, T.E.; Cartwright, D.C.; Coggeshall, S.V.; Fenstermacher, C.A.; Figueira, J.F.; Foreman, L.R.; Goldstone, P.D.; Hanson, D.E.; Harris, D.B.; Hauer, A.A.

    1988-01-01

    The goal of the Inertial Confinement Fusion Program (ICF) is to develop the ability to ignite and burn small masses of thermonuclear fuel. Although the present near-term objectives of the program are directed toward defense applications, ICF research continues to be carried out with a view to the longer term goal of commercial power production. The characteristics of a KrF laser make it an attractive candidate as an ICF driver. The KrF wavelength of 248 nm provides a target coupling that is very high at intensities of 10/sup 14/w/cm/sup 2/. In addition, the KrF laser can be repetitively operated at frequencies appropriate for a power reactor and has an intrinsically high efficiency, which allows projections to the long-term goal of energy production. The ICF program at Los Alamos consists of driver development, target design and fabrication, and target experimentation. The major effort at present is the investigation and development of KrF technology to determine its applicability for use in a laboratory driver at Los Alamos. Such a driver would be used in defense related technology studies and in areas of scientific study such as highly ionized materials and high-energy-density physics.

  18. Accelerator technology program. Progress report, July-December 1980

    SciTech Connect

    Knapp, E.A.; Jameson, R.A.

    1982-01-01

    The activities of Los Alamos National Laboratory's Accelerator Technology Division are discussed. This report covers the last six months of calendar 1980 and is organized around the Division's major projects. These projects reflect a wide variety of applications and sponsors. The major technological innovations promoted by the Pion Generator for Medical Irradiation (PIGMI) program have been developed; accelerator technologies relevant to the design of a medically practical PIGMI have been identified. A new group in AT Division deals with microwave and magnet studies; we describe the status of some of their projects. We discuss the prototype gyrocon, which has been completed, and the development of the radio-frequency quadrupole linear accelerator, which continues to stimulate interest for many possible applications. One section of this report briefly describes the results of a design study for an electron beam ion source that is ideally suited as an injector for a heavy ion linac; another section reports on a turbine engine test facility that will expose operating turbine engines to simulated maneuver forces. In other sections we discuss various activities: the Fusion Materials Irradiation Test program, the free-electron laser program, the racetrack microtron project, the Proton Storage ring, and H/sup -/ ion sources and injectors.

  19. Progress in the pulsed power Inertial Confinement Fusion program

    SciTech Connect

    Quintenz, J.P.; Matzen, M.K.; Mehlhorn, T.A.

    1996-12-01

    Pulsed power accelerators are being used in Inertial Confinement Fusion (ICF) research. In order to achieve our goal of a fusion yield in the range of 200 - 1000 MJ from radiation-driven fusion capsules, it is generally believed that {approx}10 MJ of driver energy must be deposited within the ICF target in order to deposit {approx}1 MJ of radiation energy in the fusion capsule. Pulsed power represents an efficient technology for producing both these energies and these radiation environments in the required short pulses (few tens of ns). Two possible approaches are being developed to utilize pulsed power accelerators in this effort: intense beams of light ions and z- pinches. This paper describes recent progress in both approaches. Over the past several years, experiments have successfully answered many questions critical to ion target design. Increasing the ion beam power and intensity are our next objectives. Last year, the Particle Beam Fusion Accelerator H (PBFA II) was modified to generate ion beams in a geometry that will be required for high yield applications. This 2048 modification has resulted in the production of the highest power ion beam to be accelerated from an extraction ion diode. We are also evaluating fast magnetically-driven implosions (z-pinches) as platforms for ICF ablator physics and EOS experiments. Z-pinch implosions driven by the 20 TW Saturn accelerator have efficiently produced high x- ray power (> 75 TW) and energy (> 400 kJ). Containing these x-ray sources within a hohlraum produces a unique large volume (> 6000 mm{sup 3}), long lived (>20 ns) radiation environment. In addition to studying fundamental ICF capsule physics, there are several concepts for driving ICF capsules with these x-ray sources. Progress in increasing the x-ray power on the Saturn accelerator and promise of further increases on the higher power PBFA II accelerator will be described.

  20. Chesapeake Bay program annual progress report, wetlands workgroup, December 1991. Annual progress report

    SciTech Connect

    Not Available

    1991-12-01

    The announcement by President Bush of a national no net loss wetlands policy is the result of growing public concern about the rapid loss of these important resources. Wetlands provide essential breeding, spawning, nesting and wintering habitats for a major portion of the region's fish and wildlife. In addition, wetlands function to purify surface water, moderate flood flows, maintain year round stream and river flows, reduce erosion and support commercial fishery and recreation industries. In recognition of the importance of wetlands to the environmental quality and economic productivity of the Bay, the Chesapeake Executive Council adopted the Chesapeake Bay Wetlands Policy in December 1988. The Policy includes a commitment to adopt an implementation plan. The annual report discusses the Living Resources Subcommittee's Wetlands Workgroup progress on these projects over the last year, and the near term goals for the next year. The progress to date includes work completed for the first phase and beginning to set up the second phase of the implementation plan.

  1. Geothermal drilling and completion technology development program. Quarterly progress report, October-December 1979

    SciTech Connect

    Varnado, S.G.

    1980-01-01

    The progress, status, and results of ongoing Research and Development (R and D) within the Geothermal Drilling and Completion Technology Development Program are described. The program emphasizes the development of geothermal drilling hardware, drilling fluids, and completion technology. Advanced drilling systems are also under development. The goals of the program are to develop the technology required to reduce well costs by 25% by 1982 and by 50% by 1986.

  2. Geothermal drilling and completion technology development program. Quarterly progress report, January-March 1980

    SciTech Connect

    Varnado, S.G.

    1980-04-01

    The progress, status, and results of ongoing Research and Development (R and D) within the Geothermal Drilling and Completion Technology Development Program are described. The program emphasizes the development of geothermal drilling hardware, drilling fluids, completion technology, and lost circulation control methods. Advanced drilling systems are also under development. The goals of the program are to develop the technology required to reduce well costs by 25% by 1983 and by 50% by 1987.

  3. Geothermal drilling ad completion technology development program. Semi-annual progress report, April-September 1979

    SciTech Connect

    Varnado, S.G.

    1980-05-01

    The progress, status, and results of ongoing Research and Development (R and D) within the Geothermal Drilling and Completion Technology Development Program are described. The program emphasizes the development of geothermal drilling hardware, drilling fluids, and completion technology. Advanced drilling systems are also under development. The goals of the program are to develop the technology required to reduce well costs by 25% by 1982 and by 50% by 1986.

  4. FERMILAB ACCELERATOR R&D PROGRAM TOWARDS INTENSITY FRONTIER ACCELERATORS : STATUS AND PROGRESS

    SciTech Connect

    Shiltsev, Vladimir

    2016-11-15

    The 2014 P5 report indicated the accelerator-based neutrino and rare decay physics research as a centrepiece of the US domestic HEP program at Fermilab. Operation, upgrade and development of the accelerators for the near- term and longer-term particle physics program at the Intensity Frontier face formidable challenges. Here we discuss key elements of the accelerator physics and technology R&D program toward future multi-MW proton accelerators and present its status and progress. INTENSITY FRONTIER ACCELERATORS

  5. Geothermal drilling and completion technology development program. Quarterly progress report, April-June 1980

    SciTech Connect

    Varnado, S.G.

    1980-07-01

    The progress, status, and results of ongoing research and development (R and D) within the Geothermal Drilling and Completion Technology Development Program are reported. The program emphasizes the development of geothermal drilling hardware, drilling fluids, completion technology, and lost circulation control methods. Advanced drilling systems are also under development. The goals of the program are to develop the technology required to reduce well costs by 25% by 1983 and by 50% by 1987.

  6. Geothermal drilling and completion technology development program. Annual progress report, October 1979-September 1980

    SciTech Connect

    Varnado, S.G.

    1980-11-01

    The progress, status, and results of ongoing research and development (R and D) within the Geothermal Drilling and Completion Technology Development Program are described. The program emphasizes the development of geothermal drilling hardware, drilling fluids, completion technology, and lost circulation control methods. Advanced drilling systems are also under development. The goals of the program are to develop the technology required to reduce well costs by 25% by 1983 and by 50% by 1987.

  7. Acute Disseminated Encephalomyelitis.

    PubMed

    Gray, Matthew Philip; Gorelick, Marc H

    2016-06-01

    Acute disseminated encephalomyelitis is a primarily pediatric, immune-mediated disease characterized by demyelination and polyfocal neurologic symptoms that typically occur after a preceding viral infection or recent immunization. This article presents the pathophysiology, diagnostic criteria, and magnetic resonance imaging characteristics of acute disseminated encephalomyelitis. We also present evaluation and management strategies.

  8. Semiannual progress report for the Idaho Geothermal Program, April 1 to September 30, 1980

    SciTech Connect

    Ihrig, R.R.

    1981-03-01

    The completion of the 5-MW Pilot Power Plant at the Raft River Geothermal Test Site, modification of the similar, binary cycle Prototype Power Plant, and the water treatment program that studies environmentally safe ways to inhibit corrosion and scaling in geothermal power plants and investigates corrosion resistant materials are summarized. Studies of binary geothermal cycles using mixed hydrocarbon working fluids are described as part of the continuing search for ways to produce low-cost electricity from moderate-temperature geothermal fluids. Progress is reported on studies of direct contact heat exchanger concepts, heat rejection systems, and primary heat exchangers with augmentation. As part of the now-ended series of aquaculture experiments, an unsuccessful attempt to incubate common carp embryos in geothermal waters is reported. An experiment in revegetating disturbed land at Raft River is mentioned and progress on DOE's new User Coupled Confirmation Drilling Program is described. An estimate is presented of the amount of hydrothermal energy that could be produced by the year 2000, with and without Federal assistance, for electric generation and direct applications such as industrial process heat. Progress is reported on the Marketing Assistance Program, through which technical information and assistance is provided potential users and developers of geothermal resources. Also reported is progress in DOE's Program Opportunity Notice (PON) Program demonstration projects and Program Research and Development Announcement (PRDA) Program study projects.

  9. Recent progress in NASA Langley textile reinforced composites program

    NASA Technical Reports Server (NTRS)

    Dexter, H. Benson; Harris, Charles E.; Johnston, Norman J.

    1992-01-01

    The NASA LaRC is conducting and sponsoring research to explore the benefits of textile reinforced composites for civil transport aircraft primary structures. The objective of this program is to develop and demonstrate the potential of affordable textile reinforced composite materials to meet design properties and damage tolerance requirements of advanced aircraft structural concepts. In addition to in-house research, the program was recently expanded to include major participation by the aircraft industry and aerospace textile companies. The major program elements include development of textile preforms, processing science, mechanics of materials, experimental characterization of materials, and development and evaluation of textile reinforced composite structural elements and subcomponents. The NASA Langley in-house focus is as follows: development of a science-based understanding of resin transfer molding (RTM), development of powder-coated towpreg processes, analysis methodology, and development of a performance database on textile reinforced composites. The focus of the textile industry participation is on development of multidirectional, damage-tolerant preforms, and the aircraft industry participation is in the areas of design, fabrication and testing of textile reinforced composite structural elements and subcomponents. Textile processes such as 3D weaving, 2D and 3D braiding, and knitting/stitching are being compared with conventional laminated tape processes for improved damage tolerance. Through-the-thickness reinforcements offer significant damage tolerance improvements. However, these gains must be weighed against potential loss in in-plane properties such as strength and stiffness. Analytical trade studies are underway to establish design guidelines for the application of textile material forms to meet specific loading requirements. Fabrication and testing of large structural components are required to establish the full potential of textile reinforced

  10. Inventors Center of Michigan Technical Assessment Program. Final progress report

    SciTech Connect

    Not Available

    1992-12-31

    The Technical Assessment Program at the Inventors Center of Michigan is designed to provide independent inventors with a reliable assessment of the technical merits of their proposed inventions. Using faculty from within Ferris State University`s College of Technology an assessment process examines the inventor`s assumptions, documentation, and prototypes, as well as, reviewing patent search results and technical literature to provide the inventor with a written report on the technical aspects of the proposed invention. The forms for applying for a technical assessment of an invention are included.

  11. Acute disseminated encephalomyelitis.

    PubMed

    Alper, Gulay

    2012-11-01

    Acute disseminated encephalomyelitis is an immune-mediated inflammatory and demyelinating disorder of the central nervous system, commonly preceded by an infection. It principally involves the white matter tracts of the cerebral hemispheres, brainstem, optic nerves, and spinal cord. Acute disseminated encephalomyelitis mainly affects children. Clinically, patients present with multifocal neurologic abnormalities reflecting the widespread involvement in central nervous system. Cerebrospinal fluid may be normal or may show a mild pleocytosis with or without elevated protein levels. Magnetic resonance image (MRI) shows multiple demyelinating lesions. The diagnosis of acute disseminated encephalomyelitis requires both multifocal involvement and encephalopathy by consensus criteria. Acute disseminated encephalomyelitis typically has a monophasic course with a favorable prognosis. Multiphasic forms have been reported, resulting in diagnostic difficulties in distinguishing these cases from multiple sclerosis. In addition, many inflammatory disorders may have a similar presentation with frequent occurrence of encephalopathy and should be considered in the differential diagnosis of acute disseminated encephalomyelitis.

  12. Nuclear technology programs. Semiannual progress report, April--September 1991

    SciTech Connect

    Not Available

    1993-07-01

    This document reports on the work done by the Nuclear Technology Programs of the Chemical Technology Division, Argonne National Laboratory, in the period April through September 1991. These programs involve R & D in three areas: applied physical chemistry, separation science and technology, and nuclear waste management. The work in applied physical chemistry includes investigations into the processes that control the release and transport of fission products under accident-like conditions in a light water reactor, the thermophysical properties of the metal fuel in the Integral Fast Reactor, and the properties of selected materials in environments simulating those of fusion energy systems. In the area of separation science and technology, the bulk of the effort is concerned with developing and implementing processes for the removal and concentration of actinides from waste streams contaminated by transuranic elements. In the area of waste management, investigations are underway on the performance of materials in projected nuclear repository conditions to provide input to the licensing of the nation`s high-level waste repositories.

  13. Nuclear Technology Programs semiannual progress report, October 1988--March 1989

    SciTech Connect

    Harmon, J.E.

    1990-12-01

    This document reports on the work done by the Nuclear Technology Programs of the Chemical Technology Division, Argonne National Laboratory, in the period October 1988--March 1989. These programs involve R&D in three areas: applied physical chemistry, separation science and technology, and nuclear waste management. The work in applied physical chemistry includes investigations into the processes that control the release and transport of fission products under accident-like conditions, the thermophysical properties of metal fuel and blanket materials of the Integral Fast Reactor, and the properties of selected materials in environments simulating those of fusion energy systems. In the area of separation science and technology, the bulk of the effort is concerned with developing and implementing processes for the removal and concentration of actinides from waste streams contaminated by transuranic elements. Another effort is concerned with examining the feasibility of substituting low-enriched for high-enriched uranium in the production of fission product {sup 99}Mo. In the area of waste management, investigations are underway on the performance of materials in projected nuclear repository conditions to provide input to the licensing of the nation`s high-level waste repositories. 127 refs., 76 figs., 103 tabs.

  14. Nuclear Technology Programs semiannual progress report, October 1990--March 1991

    SciTech Connect

    1992-12-01

    This document reports on the work done by the Nuclear Technology Programs of the Chemical Technology Division, Argonne National Laboratory, in the period October 1990--March 1991. These programs involve R&D in three areas: applied physical chemistry, separation science and technology, and nuclear waste management. The work in applied physical chemistry includes investigations into the processes that control the release and transpose of fission products under accident-like conditions in a light water reactor, the thermophysical properties of the metal fuel in the Integral Fast Reactor, and the properties of selected materials in environments simulating those of fusion energy systems. In the area of separation science and technology, the bulk of the effort is concerned with developing and implementing processes for the removal and concentration of actinides from waste streams contaminated by transuranic elements. In the area of waste management, investigations are underway on the performance of materials in projected nuclear repository conditions to provide input to the licensing of the nation`s high-level waste repositories.

  15. Nuclear Technology Programs semiannual progress report, April-- September 1990

    SciTech Connect

    Harmon, J.E.

    1992-06-01

    This document reports on the work done by the Nuclear Technology Programs of the Chemical Technology Division, Argonne National Laboratory, in the period April--September 1990. These programs involve R&D in three areas: applied physical chemistry, separation science and technology, and nuclear waste management. The work in applied physical chemistry includes investigations into the processes that control the release and transport of fission products under accident-like conditions in a light water reactor, the thermophysical properties of the metal fuel in the Integral Fast Reactor, and the properties of selected materials in environments simulating those of fusion energy systems. In the area of separation science and technology, the bulk of the effort is concerned with developing and implementing processes for the removal and concentration of actinides from waste streams contaminated by transuranic elements. In the area of waste management, investigations are underway on the performance of materials in projected nuclear repository conditions to provide input to the licensing of the nation`s high-level waste repositories.

  16. Nuclear Technology Programs semiannual progress report, April-- September 1990

    SciTech Connect

    Harmon, J.E.

    1992-06-01

    This document reports on the work done by the Nuclear Technology Programs of the Chemical Technology Division, Argonne National Laboratory, in the period April--September 1990. These programs involve R D in three areas: applied physical chemistry, separation science and technology, and nuclear waste management. The work in applied physical chemistry includes investigations into the processes that control the release and transport of fission products under accident-like conditions in a light water reactor, the thermophysical properties of the metal fuel in the Integral Fast Reactor, and the properties of selected materials in environments simulating those of fusion energy systems. In the area of separation science and technology, the bulk of the effort is concerned with developing and implementing processes for the removal and concentration of actinides from waste streams contaminated by transuranic elements. In the area of waste management, investigations are underway on the performance of materials in projected nuclear repository conditions to provide input to the licensing of the nation's high-level waste repositories.

  17. Nuclear technology programs; Semiannual progress report, October 1989--March 1990

    SciTech Connect

    Harmon, J.E.

    1992-01-01

    This document reports on the work done by the Nuclear Technology Programs of the Chemical Technology Division, Argonne National Laboratory, in the period October 1989--March 1990. These programs involve R&D in three areas: applied physical chemistry, separation science and technology, and nuclear waste management. The work in applied physical chemistry includes investigations into the processes that control the release and transport of fission products under accident-like conditions, the thermophysical properties of metal fuel and blanket materials of the Integral Fast Reactor, and the properties of selected materials in environments simulating those of fusion energy systems. In the area of separation science and technology, the bulk of the effort is concerned with developing and implementing processes for the removal and concentration of actinides from waste streams contaminated by transuranic elements. Another effort is concerned water waste stream generated in production of 2,4,6-trinitrotoluene. In the area of waste management, investigations are underway on the performance of materials in projected nuclear repository conditions to provide input to the licensing of the nation`s high-level waste repositories.

  18. Biofuels feedstock development program. Annual progress report for 1992

    SciTech Connect

    Wright, L.L.; Cushman, J.H.; Ehrenshaft, A.R.; McLaughlin, S.B.; McNabb, W.A.; Martin, S.A.; Ranney, J.W.; Tuskan, G.A.; Turhollow, A.F.

    1993-11-01

    The Department of Energy`s (DOE`s) Biofuels Feedstock Development Program (BFDP) leads the nation in the research, development, and demonstration of environmentally acceptable and commercially viable dedicated feedstock supply systems (DFSS). The purpose of this report is to highlight the status and accomplishments of the research that is currently being funded by the BFDP. Highlights summarized here and additional accomplishments are described in more detail in the sections associated with each major program task. A few key accomplishments include (1) development of a methodology for doing a cost-supply analysis for energy crops and the application of that methodology to looking at possible land use changes around a specific energy facility in East Tennessee; (2) preliminary documentation of the relationship between woody crop plantation locations and bird diversity at sites in the Midwest, Canada, and the pacific Northwest supplied indications that woody crop plantations could be beneficial to biodiversity; (3) the initiation of integrated switchgrass variety trials, breeding research, and biotechnology research for the south/southeast region; (4) development of a data base management system for documenting the results of herbaceous energy crop field trials; (5) publication of three issues of Energy Crops Forum and development of a readership of over 2,300 individuals or organizations as determined by positive responses on questionnaires.

  19. Overview of Compact Toroidal Hybrid research program progress and plans

    NASA Astrophysics Data System (ADS)

    Maurer, David; Ennis, David; Hanson, James; Hartwell, Gregory; Herfindal, Jeffrey; Knowlton, Stephen; Ma, Xingxing; Pandya, Mihir; Roberds, Nicholas; Ross, Kevin; Traverso, Peter

    2016-10-01

    disruptive behavior on the level of applied 3D magnetic shaping; (2) test and advance the V3FIT reconstruction code and NIMROD modeling of CTH; and (3) study the implementation of an island divertor. Progress towards these goals and other developments are summarized. The disruptive density limit exceeds the Greenwald limit as the vacuum transform is increased, but a threshold for avoidance is not observed. Low- q disruptions, with 1.1 < q (a) <2.0, cease to occur if the vacuum transform is raised above 0.07. Application of vacuum transform can reduce and eliminate the vertical drift of elongated discharges that would otherwise be vertically unstable. Reconstructions using external magnetics give accurate estimates for quantities near the plasma boundary, and internal diagnostics have been implemented to extend the range of accuracy into the plasma core. Sawtooth behavior has been reproducibly modified with external transform and NIMROD is used to model these observations and reproduces experimental trends. An island divertor design has begun with connection length studies to model energy deposition on divertor plates located in an edge 1/3 island as well as the study of a non-resonant divertor configuration. This work is supported by U.S. Department of Energy Grant No. DE-FG02-00ER54610.

  20. Inertial fusion program. Progress report, January 1-June 30, 1978

    SciTech Connect

    Skoberne, F.

    1980-05-01

    Studies and experiments aimed at investigating the possibility of restoring wavefront quality in optical systems through phase conjugation are summarized, and work that could lead to the development of highly damage-resistant isolators is discussed. The effects of various parameters on pulse-energy uniformity and of multipass extraction on laser efficiency are reported. Results of equation-of-state, shock propagation, multiburst simulation, and opacity measurements are discussed. Target designs are described that should provide a smooth transition from the exploding-pusher regime of experiments to that of isentropic compression. Progress in target fabrication techniques toward creating a 20-times-liquid-density target are outlined, and efforts that led to the extension of our neutron detection capability to levels of less than 10/sup 3/ n are summarized. The results of various studies of laser fusion application, e.g., for producing ultrahigh-temperature process heat or hydrogen from water decomposition are presented, as well as investigations of fusion-fission hybrids for the production of /sup 233/U from /sup 232/Th.

  1. UCSD geothermal chemistry program; Annual progress report, FY 1989

    SciTech Connect

    Weare, J.H.

    1989-10-01

    The development of a geothermal resource requires a considerable financial commitment. As in other energy extraction ventures, the security of this investment can be jeopardized by the uncertain behavior of the resource under operating conditions. Many of the most significant problems limiting the development of geothermal power are related to the chemical properties of the high temperature and highly pressured formation fluids from which the energy is extracted. When the pressure and temperature conditions on these fluids are changed either during the production phase (pressure changes) or during the extraction phase (temperature changes) of the operation, the fluids which were originally in equilibrium under the new conditions by precipitation of solid materials (scales) or release of dissolved gases (some toxic) in the formation and well bores or in the plant equipment. Unfortunately, predicting the behavior of the production fluids is difficult, because it is a function of many variables. In order to address these problems the Department of Energy is developing a computer model describing the chemistry of geothermal fluids. The model under development at UCSD is based on recent progress in the physical chemistry of concentrated aqueous solutions, and is covered in this report.

  2. Compact Toroidal Hybrid Research Program: Recent Progress and Future Plans

    NASA Astrophysics Data System (ADS)

    Maurer, D. A.; Cianciosa, M.; Hanson, J. D.; Hartwell, G. J.; Hebert, J. D.; Herfindal, J. L.; Knowlton, S. F.; Archmiller, M. C.; Traverso, P.; Pandya, M.; Ma, X.

    2012-10-01

    Understanding the control and avoidance of major disruptions in current carrying toroidal plasmas is important in mitigating the effects of rapid loss of confinement in future devices. The Compact Toroidal Hybrid (CTH) experiment is investigating the passive avoidance of disruptions with the addition of a small amount of vacuum transform provided by external coils. In ohmically-driven stellarator plasmas no disruptions of any kind are observed if the vacuum transform exceeds ˜ 0.11. Recent progress on the suppression of low-qa (high a), density limit, and vertically unstable plasma disruptions is overviewed. Interpretation of these results makes use of 3D equilibrium reconstructions using the V3FIT code [1]. Several new diagnostic tools have recently been developed and implemented on CTH. These new research tools include multi-chord interferometry, bolometry, Hα emission detection, a two-color soft x-ray camera, and upgraded magnetic sensor arrays. In addition to these diagnostic improvements, a new 200 kW gyrotron system will provide additional heating power for stellarator target plasmas. Future research directions and plans will also be discussed. [4pt] [1] J. D. Hanson, S. P. Hirshman, S. F. Knowlton, L. L. Lao, E. A. Lazarus, J. M. Shields, Nucl. Fusion, 49 (2009) 075031

  3. Inertial fusion program. Progress report, July 1-December 31, 1978

    SciTech Connect

    Perkins, R.B.

    1980-11-01

    Progress at Los Alamos Scientific Laboratory (LASL) in the development of high-energy short-pulse CO/sub 2/ laser systems for fusion research is reported. Improvements to LASL's two-beam system, Gemini, are outlined and experimental results are discussed. Our eight-beam system, Helios, was fired successfully on target for the first time, and became the world's most powerful gas laser for laser fusion studies. Work on Antares, our 100- to 200-TW target irradiation system, is summarized, indicating that design work and building construction are 70 and 48% complete, respectively. A baseline design for automatic centering of laser beams onto the various relay mirrors and the optical design of the Antares front end are discussed. The results of various fusion reactor studies are summarized, as well as investigations of synthetic-fuel production through application of fusion energy to hydrogen production by thermochemical water splitting. Studies on increased efficiency of energy extraction in CO/sub 2/ lasers and on lifetimes of cryogenic pellets in a reactor environment are summarized, as well as the results of studies on pellet injection, tracking, and beam synchronization.

  4. Ten years of progress in the Superfund Program

    SciTech Connect

    Clay, D.R. )

    1991-02-01

    Superfund celebrated its tenth anniversary in December 1990. The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) - popularly known as Superfund - was passed into law in December 1980 in the wake of such incidents as Love Canal and the Valley of the Drums. The program was designed to clean up uncontrolled hazardous waste sites and, during the past ten years, thousands of actions have been taken to protect human health and the environment from the hazards posed by those sites. EPA believes that goal is best met by its strategy: make sites safer - control immediate threats; enforce aggressively; make sites cleaner - worst problems at worst sites first; bring new technology to bear on the problem.

  5. Hydrologic resources management program. FY 1995 progress report

    SciTech Connect

    Smith, D.K.; Esser, B.K.; Kenneally, J.M.

    1996-03-01

    This report presents the results of FY 1995 technical studies conducted by the Lawrence Livermore National Laboratory (LLNL) as part of the Hydrology and Radionuclide Migration Program (HRMP), a multi-agency program sponsored by the U.S. Department of Energy, Nevada Operations Office (DOE/NV), to address the environmental consequences of nuclear weapons testing at the Nevada Test Site (NTS). A priority is to better characterize the complex near-field environment in order to assess and predict the movement of radionuclides in groundwater. Other participating organizations include the Los Alamos National Laboratory (LANL), the U.S. Geological Survey (USGS) and the Desert Research Institute (DRI) of the University of Nevada. A radiologic source term in excess of 10{sup 8} curies of tritium, fission products, activation products and actinides is residual from more than three decades of underground nuclear weapons testing at the Nevada Test Site (NTS). Burial depths to insure containment of these explosions necessitated firing approximately one third of the more than 800 underground nuclear tests within one cavity radius or below the static water table. Work at LLNL has focused on studies of radionuclide transport under saturated, partially saturated or unsaturated conditions as well as investigations of the stable, radiogenic and cosmogenic isotope systematics of NTS groundwaters. LLNL has prioritized these studies because of the significance for potential radionuclide migration at the Nevada Test Site. LLNL utilizes expertise in nuclear weapons testing, radiochemical diagnostics, nuclear test phenomenology, mass spectrometry, aqueous geochemistry and field and laboratory studies of radionuclide migration to bring a unique measurement and interpretative capability to this research.

  6. Hydrology and radionuclide migration program 1987 progress report

    SciTech Connect

    Marsh, K.V.

    1991-03-01

    This report presents results from the Lawrence Livermore National Laboratory's participation in the Hydrology and Radionuclide Migration Program at the Nevada Test Site (NTS) during the fiscal year 1987. The report discussed initial data from a new well (UE20n-1) drilled at the Cheshire site; presents a description of a proposed laboratory study of migration of colloids in fractured media; lists data collected during the drilling and initial sampling of UE20n-1; and describes a tentative proposal for work to be performed in FY88 by Lamont-Doherty Geological Observatory. Groundwater sampled from the new well at the Cheshire site contains tritium concentrations comparable to those measured in previous years from locations above and within the Cheshire cavity. This presence of tritium, as well as several other radionuclides, in a well 100 m away from the cavity region indicates transport of radionuclides, validates a proposed model of the flow path, and provides data on rates of groundwater flow. Previous work at the Cheshire site has shown that radionuclides are transported by colloids through fractured media. However, we have no data that can be used for predictive modeling, and existing theories are not applicable. While physical transport mechanisms of sub-micrometer colloids to defined mineral surfaces are well known, predictions based on well-defined conditions differ from experimental observations by orders of magnitude. The U.C. Berkeley group has designed a laboratory experiment to quantify colloid retention and permeability alteration by the retained colloids.

  7. Herbaceous Energy Corps Program: Annual progress report for FY 1986

    SciTech Connect

    Cushman, J.H.; Turhollow, A.F.; Johnston, J.W.

    1987-05-01

    This report describes the activities and accomplishments of the Herbaceous Energy Crops Program (HECP) for the year ending September 30, 1986. HECP is devoted to research on the development of terrestrial, nonwoody plant species for use as energy feedstocks. HECP emphasizes lignocellulosic forage crops. In FY 1986 screening and selection trials continued on 25 species of perennial and annual grasses and legumes in five projects in the Southeast and the Midwest-Lake States regions. Research also continued on the development of winter rapeseed as a diesel-fuel substitute. Activities in FY 1986 included genetic crosses and selections to incorporate atrazine resistance, development of Canola-quality winter rapeseed for the Southeast, and development of dwarf varieties. Production practices for double-cropped winter rapeseed in the Southeast were also examined. Exploratory research efforts in FY 1986 included the physiology and biochemistry of hydrocarbon production in latex-bearing plants, the productivity of cattail stands under sustained harvesting, the development of tissue culture techniques for hard-to-culture sorghum genotypes, and the start of a study to measure sustained productivity of old-field successional vegetation. Environmental and economic analyses in FY 1986 included studies on the uses of wetlands and wet soils, the use of lignocellulosic crops as an alcohol feedstock, the potential of direct combustion of lignocellulosic crops, and existing oilseed extraction facilities. 6 refs., 12 figs., 15 tabs.

  8. Herbaceous Energy Crops Program. Annual progress report for FY 1985

    SciTech Connect

    Cushman, J.H.; Turhollow, A.F.; Johnston, J.W.

    1986-04-01

    This report describes the activities and accomplishments of the Herbaceous Energy Crops Program (HECP) for the year ending September 30, 1985. HECP emphasizes lignocellulosic forage crops. In FY 1985 screening and selection trails began on seven species of perennial and annual grasses and legumes in five projects in the Southeast and the Midwest-Lake State regions. Research also continued on the development of winter rapeseed as a disel-fuel substitute. Activities in FY 1985 included crosses and selections to incorporate atrazine resistance and reduced vernalization requirements in genotypes with desirable seed and oil qualities. Exploratory research efforts in FY 1985 included the physiology and biochemistry of hydrocarbon production in latex bearing plants, the productivity of cattail stands under sustained harvesting, and the development of tissue culture techniques for hard-to-culture sorghum genotypes. Environmental and economic analyses in FY 1985 included completion of a resource assessment of the southwestern United States, a study on successful new crop introductions, and initiation of studies on near-term markets for lignocellulosic energy crops and on vegetable oil extraction facilities. 8 figs., 2 tabs.

  9. Progress in BNL High-Temperature Hydrogen Combustion Research Program

    SciTech Connect

    Ciccarelli, G.; Ginsberg, T.; Boccio, J.; Curtiss, J.; Economos, C.; Jahelka, J.; Sato, K.

    1992-01-01

    The objectives of the BNL High-Temperature Hydrogen Combustion Research Program are discussed. The experimental facilities are described and two sets of preliminary experiments are presented. Chemical reaction time experiments have been performed to determine the length of time reactive mixtures of interest can be kept at temperature before reaction in the absence of ignition sources consumes the reactants. Preliminary observations are presented for temperatures in the range 588K--700K. Detonation experiments are described in which detonation cell width is measured as a measure of mixture sensitivity to detonation. Preliminary experiments are described which are being carried out to establish data reproducibility with previous measurements in the literature and to test out and refine experimental methods. Intensive studies of hydrogen combustion phenomena were carried out during the 1980s. Much of this effort was driven by issues related to nuclear reactor safety. The high-speed'' combustion phenomena of flame acceleration, deflagration-to-detonation transition, direct initiation of detonation, detonation propagation, limits of detonation in tubes and channels, transmission of detonations from confined to unconfined geometry and other related phenomena were studied using a variety of gaseous fuel-oxidant systems, including hydrogen-steam-air systems of interest in reactor safety studies. Several reviews are available which document this work [Lee, 1989; Berman, 1986].

  10. Progress in BNL High-Temperature Hydrogen Combustion Research Program

    SciTech Connect

    Ciccarelli, G.; Ginsberg, T.; Boccio, J.; Curtiss, J.; Economos, C.; Jahelka, J.; Sato, K.

    1992-12-31

    The objectives of the BNL High-Temperature Hydrogen Combustion Research Program are discussed. The experimental facilities are described and two sets of preliminary experiments are presented. Chemical reaction time experiments have been performed to determine the length of time reactive mixtures of interest can be kept at temperature before reaction in the absence of ignition sources consumes the reactants. Preliminary observations are presented for temperatures in the range 588K--700K. Detonation experiments are described in which detonation cell width is measured as a measure of mixture sensitivity to detonation. Preliminary experiments are described which are being carried out to establish data reproducibility with previous measurements in the literature and to test out and refine experimental methods. Intensive studies of hydrogen combustion phenomena were carried out during the 1980s. Much of this effort was driven by issues related to nuclear reactor safety. The ``high-speed`` combustion phenomena of flame acceleration, deflagration-to-detonation transition, direct initiation of detonation, detonation propagation, limits of detonation in tubes and channels, transmission of detonations from confined to unconfined geometry and other related phenomena were studied using a variety of gaseous fuel-oxidant systems, including hydrogen-steam-air systems of interest in reactor safety studies. Several reviews are available which document this work [Lee, 1989; Berman, 1986].

  11. Environmental surveillance program. Quarterly progress report, July--September, 1993

    SciTech Connect

    Walker, D.W.; Hall, L.F.; Downs, J.

    1996-02-01

    This report contains data developed from monitoring site measurements and laboratory analyses of environmental samples that were collected during the period of July-September, 1993. Because some laboratory procedures are lengthy and could adversely affect the desired timeliness of reports, results of some analyses from this time period will be included in the next quarterly report. Quarterly reports, then, will be routine periodic documents that present continually updated information concerning the potential presence of environmental contaminants in the vicinity of the Idaho National Engineering Laboratory (INEL). During the third calendar quarter of 1993, Environmental Surveillance Program (ESP) measurements did not reveal unexpected levels of contaminants in any environmental samples measured or analyzed. Most of the results reported in this document are related to off-site air and ground water measurements. Future reports will include results of monitoring at additional locations and for additional environmental materials. Annual reports from the ESP will contain data generated during the previous four calendar quarters, and will display measurement trends for various combinations of locations, contaminants and environmental media. The annual report will also include more interpretive material and discussions than will normally be found in quarterly reports.

  12. Accelerator technology program. Progress report, July-December 1981

    SciTech Connect

    Knapp, E.A.; Jameson, R.A.

    1982-08-01

    We report on the major projects of the Los Alamos National Laboratory's Accelerator Technology Division during the last 6 months of calendar year 1981. We have continued work on the radio-frequency quadrupole linear accelerator; we are doing studies of octupole focusing. We have completed the design study on an unusual electron-linear radiographic machine that could obtain x rays of turbine engines operating under simulated flight-maneuver conditions on a centrifuge. In September we completed the 5-y PIon Generator for Medical Irradiation (PIGMI) program to develop the concept and technology for an accelerator-based facility to treat cancer in a hospital environment. The design and construction package for the site, building, and utilities for the Fusion Materials Irradiation Test (FMIT) facility has been completed, and we have begun to concentrate on tests of the rf power equipment and on the design, procurement, and installation of the 2-MeV proto-type accelerator. The Proton Storage Ring project has continued to mature. The main effort on the racetrack microtron (RTM) has been on the design and construction of various components for the demonstration RTM. On the gyrocon radio-frequency generator project, the gyrocon was rebuilt with a new electron gun and new water-cooled gun-focus coil; these new components have performed well. We have initiated a project to produce a klystron analysis code that will be useful in reducing the electrical-energy demand for accelerators. A free-electron laser amplifier experiment to test the performance of a tapered wiggler at high optical power has been successfully completed.

  13. Site Protection Program and Progress Report of Ali Observatory, Tibet

    NASA Astrophysics Data System (ADS)

    Yao, Yongqiang; Zhou, Yunhe; Wang, Xiaohua; He, Jun; Zhou, Shu

    2015-08-01

    The Ali observatory, Tibet, is a promising new site identified through ten year site survey over west China, and it is of significance to establish rules of site protection during site development. The site protection program is described with five aspects: site monitoring, technical support, local government support, specific organization, and public education. The long-term sky brightness monitoring is ready with site testing instruments and basic for light pollution measurement; the monitoring also includes directions of main light sources, providing periodical reports and suggestions for coordinating meetings. The technical supports with institutes and manufacturers help to publish lighting standards and replace light fixtures; the research pays special attention to the blue-rich sources, which impact the important application of high altitude sites. An official leading group towards development and protection of astronomical resources has been established by Ali government; one of its tasks is to issue regulations against light pollution, including special restrictions of airport, mine, and winter heating, and to supervise lighting inspection and rectification. A site protection office under the official group and local astronomical society are organized by Ali observatory; the office can coordinate in government levels and promote related activities. A specific website operated by the protection office releases activity propaganda, evaluation results, and technical comparison with other observatories. Both the site protection office and Ali observatory take responsibility for public education, including popular science lectures, light pollution and energy conservation education. Ali Night Sky Park has been constructed and opens in 2014, and provides a popular place and observational experience. The establishment of Ali Observatory and Night Sky Park brings unexpected social influence, and the starry sky trip to Ali becomes a new format of culture

  14. Strengthening Scientific Verbal Behavior: An Experimental Comparison of Progressively Prompted and Unprompted Programmed Instruction and Prose Tutorials

    ERIC Educational Resources Information Center

    Davis, Darrel R.; Bostow, Darrel E.; Heimisson, Gudmundur T.

    2007-01-01

    Web-based software was used to deliver and record the effects of programmed instruction that progressively added formal prompts until attempts were successful, programmed instruction with one attempt, and prose tutorials. Error-contingent progressive prompting took significantly longer than programmed instruction and prose. Both forms of…

  15. Intraobserver and Interobserver Agreement of Structural and Functional Software Programs for Measuring Glaucoma Progression.

    PubMed

    Moreno-Montañés, Javier; Antón, Vanesa; Antón, Alfonso; Larrosa, José M; Martinez-de-la-Casa, José María; Rebolleda, Gema; Ussa, Fernando; García-Granero, Marta

    2017-04-01

    regarding questions about glaucoma progression (κ, 0.39; 95% CI, 0.32-0.48) and consideration about treatment changes (κ, 0.39; 95% CI, 0.32-0.48). The factors associated with agreement were the glaucoma stage and case difficulty. There was substantial intraobserver agreement but moderate interobserver agreement among glaucoma specialists using 2 glaucoma progression software packages. These data suggest that these glaucoma progression software packages are insufficient to obtain high interobserver agreement in both devices except in patients with no progression. The low agreement regarding progression or treatment changes suggests that both software programs used in isolation are insufficient for decision making.

  16. Magnetic resonance imaging diagnosis of disseminated necrotizing leukoencephalopathy

    SciTech Connect

    Atlas, S.W.; Grossman, R.I.; Packer, R.J.; Goldberg, H.I.; Hackney, D.B.; Zimmerman, R.A.; Bilaniuk, L.T.

    1987-01-01

    Disseminated necrotizing leukoencephalopathy is a rare syndrome of progressive neurologic deterioration seen most often in patients who have received central nervous system irradiation combined with intrathecal or systemic chemotherapy in the treatment or prophylaxis of various malignancies. Magnetic resonance imaging was more sensitive than computed tomography in detecting white matter abnormalities in the case of disseminated necrotizing leukoencephalopathy reported here. Magnetic resonance imaging may be useful in diagnosing incipient white matter changes in disseminated necrotizing leukoencephalopathy, thus permitting early, appropriate therapeutic modifications.

  17. Semiannual progress report for the Idaho Geothermal Program, April 1-September 30, 1979

    SciTech Connect

    Ihrig, R.R.

    1980-03-01

    Progress made by the Idaho Geothermal Program between March 31 and September 30, 1979 is discussed. Geothermal well tests at the Raft River geothermal site, facility construction, and the first hydraulic fracture treatment of a geothermal well are summarized. The results of direct applications experiments are described briefly, including experiments in aquaculture, agriculture, fluidized bed space heating, fluidized bed food drying, essential oil extraction, and geothermal assisted conversion of biomass to ethanol. Improvements to the binary cycle prototype power plant at Raft River, construction progress on the 5-MW pilot plant, and experimental work on direct contact heat exchangers are discussed. Also outlined is progress on environmental studies at Raft River, including a brief discussion of socioeconomic impacts of geothermal development on Cassia County, Idaho. Results are presented of a 48-industry survey conducted to determine industry's views of the technology barriers to accelerating hydrothermal energy commercialization. A projection summarizes the capital and manpower needed through 1987 to place 6800 MW of direct applications development online. Progress reports are also included on DOE's Program Opportunity Notice (PON) Program demonstration projects and DOE's Program Research and Development Announcement (PRDA) Program study projects.

  18. Evaluation of Visual Field Progression in Glaucoma: Quasar Regression Program and Event Analysis.

    PubMed

    Díaz-Alemán, Valentín T; González-Hernández, Marta; Perera-Sanz, Daniel; Armas-Domínguez, Karintia

    2016-01-01

    To determine the sensitivity, specificity and agreement between the Quasar program, glaucoma progression analysis (GPA II) event analysis and expert opinion in the detection of glaucomatous progression. The Quasar program is based on linear regression analysis of both mean defect (MD) and pattern standard deviation (PSD). Each series of visual fields was evaluated by three methods; Quasar, GPA II and four experts. The sensitivity, specificity and agreement (kappa) for each method was calculated, using expert opinion as the reference standard. The study included 439 SITA Standard visual fields of 56 eyes of 42 patients, with a mean of 7.8 ± 0.8 visual fields per eye. When suspected cases of progression were considered stable, sensitivity and specificity of Quasar, GPA II and the experts were 86.6% and 70.7%, 26.6% and 95.1%, and 86.6% and 92.6% respectively. When suspected cases of progression were considered as progressing, sensitivity and specificity of Quasar, GPA II and the experts were 79.1% and 81.2%, 45.8% and 90.6%, and 85.4% and 90.6% respectively. The agreement between Quasar and GPA II when suspected cases were considered stable or progressing was 0.03 and 0.28 respectively. The degree of agreement between Quasar and the experts when suspected cases were considered stable or progressing was 0.472 and 0.507. The degree of agreement between GPA II and the experts when suspected cases were considered stable or progressing was 0.262 and 0.342. The combination of MD and PSD regression analysis in the Quasar program showed better agreement with the experts and higher sensitivity than GPA II.

  19. Computer software management, evaluation, and dissemination

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The activities of the Computer Software Management and Information Center involving the collection, processing, and distribution of software developed under the auspices of NASA and certain other federal agencies are reported. Program checkout and evaluation, inventory control, customer services and marketing, dissemination, program maintenance, and special development tasks are discussed.

  20. Consolidated Fuel Reprocessing Program. Progress report, January 1-March 31, 1985

    SciTech Connect

    Not Available

    1985-04-01

    The DOE has concentrated all US research and development on fuel reprocessing into one major program - the Consolidated Fuel Reprocessing Program (CFRP) - under the management of the Oak Ridge National Laboratory and the Oak Ridge Operations Office. Other major program participants are GA Technologies, Inc., where reprocessing research and development on the HTGR fuel cycle are done, and the Hanford Engineering Development Laboratory (HEDL). The coverage is generally overview in nature. Experimental details and data have been limited to (1) make the report more concise and (2) meet the requirements which would qualify the report for unrestricted distribution in the open literature. All research and development on civilian power reactor fuel reprocessing in the United States is managed under the Consolidated Fuel Reprocessing Program (CFRP) centered at Oak Ridge National Laboratory (ORNL). Technical progress is reported in overview fashion in this series of quarterly progress reports.

  1. TP Atlas: integration and dissemination of advances in Targeted Proteins Research Program (TPRP)-structural biology project phase II in Japan.

    PubMed

    Iwayanagi, Takao; Miyamoto, Sei; Konno, Takeshi; Mizutani, Hisashi; Hirai, Tomohiro; Shigemoto, Yasumasa; Gojobori, Takashi; Sugawara, Hideaki

    2012-09-01

    The Targeted Proteins Research Program (TPRP) promoted by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan is the phase II of structural biology project (2007-2011) following the Protein 3000 Project (2002-2006) in Japan. While the phase I Protein 3000 Project put partial emphasis on the construction and maintenance of pipelines for structural analyses, the TPRP is dedicated to revealing the structures and functions of the targeted proteins that have great importance in both basic research and industrial applications. To pursue this objective, 35 Targeted Proteins (TP) Projects selected in the three areas of fundamental biology, medicine and pharmacology, and food and environment are tightly collaborated with 10 Advanced Technology (AT) Projects in the four fields of protein production, structural analyses, chemical library and screening, and information platform. Here, the outlines and achievements of the 35 TP Projects are summarized in the system named TP Atlas. Progress in the diversified areas is described in the modules of Graphical Summary, General Summary, Tabular Summary, and Structure Gallery of the TP Atlas in the standard and unified format. Advances in TP Projects owing to novel technologies stemmed from AT Projects and collaborative research among TP Projects are illustrated as a hallmark of the Program. The TP Atlas can be accessed at http://net.genes.nig.ac.jp/tpatlas/index_e.html .

  2. Dissemination research in cancer control: where are we and where should we go?

    PubMed

    Bowen, Deborah J; Sorensen, Glorian; Weiner, Bryan J; Campbell, Marci; Emmons, Karen; Melvin, Cathy

    2009-05-01

    Dissemination of evidence-based programs and policies is a critical final step in reducing the burden of cancer in the general public. Yet, we have not been fully successful to date in improving clinical or public health practice by disseminating programs found to be effective in research. Therefore, research is needed into the dissemination process and outcomes to enable better efforts in the future. This paper explores the definitions and models used for dissemination, the designs of dissemination studies, and possible research questions in dissemination research, all focused on cancer prevention and control. We hope that this paper will encourage dissemination research in our field.

  3. Disseminated granulomatous meningoencephalomyelitis in a dog

    PubMed Central

    Fisher, Margaret

    2002-01-01

    A 6-year-old, intact, female miniature Doberman pinscher was evaluated for lethargy, intermittent back pain, and unstable gait. Physical and neurological findings included bradycardia, hypothermia, hyperesthesia, progressive and ascending ataxia, and proprioceptive deficits in all limbs. Laboratory findings and magnetic resonance imaging were consistent with disseminated granulomatous meningoencephalomyelitis, confirmed later by microscopy. PMID:11802671

  4. Maryland controlled fusion research program. Progress report, November 1, 1992--October 31, 1993

    SciTech Connect

    Antonsen, T.M. Jr.; Drake, J.F.; Finn, J.M.; Guzdar, P.; Hassam, A.; Liu, C.S.; Ott, E.

    1993-05-01

    In recent years, members of the Maryland Plasma Theory Group have made significant contributions to the national fusion theory program, and, in many cases, these theoretical developments helped to interpret experimental results and to design new experimental programs. In this paper, we summarize the technical progress in four major areas of tokamak research: (a) L/H transition and edge turbulence and transport; (b) active control of micro-turbulence and transport; (c) major disruptions; and (d) the sawtooth crash.

  5. Exploratory energy research program at the University of Michigan. Progress report

    SciTech Connect

    Kerr, W.

    1980-12-08

    A DOE grant to the University of Michigan for an Exploratory Energy Research Program is being used by the U-M Office of Energy Research (OER) to support faculty research and grad student research assistantships. Progress on activity during the first six months of the program is described and brief status reports on 20 energy-related faculty research projects in the physical, engineering, biological, and behavioral sciences are presented.

  6. Short-rotation woody-crops program. Quarterly progress report for period ending August 31, 1981

    SciTech Connect

    Cushman, J.H.; Ranney, J.W.

    1982-04-01

    Progress of twenty-one projects in the Short Rotation Woody Crops Program is summarized for the period June 1 through August 31, 1981. Individual quarterly reports included from each of the projects discuss accomplishments within specific project objectives and identify recent papers and publications resulting from the research. The major program activities are species screening and genetic selection, stand establishment and cultural treatment, and harvest, collection, transportation, and storage.

  7. Fossil Energy Program quarterly progress report for the period ending March 31, 1986

    SciTech Connect

    Bradley, R.A.

    1986-06-01

    This report covers progress made during the period January 1 through March 31, 1986, for research and development projects that contribute to the advancement of various fossil energy technologies. Projects on the Fossil Energy Program are supported by DOE Office of Fossil Energy, DOE Office of Basic Energy Sciences, and the Tennessee Valley Authority. The Fossil Energy Program organization chart is shown in the Appendix.

  8. Evidence of Criterion Validity for One Pharmacy School’s Progress Examination Program

    PubMed Central

    Haltom, Wes R.

    2016-01-01

    Objective. To provide evidence that the progress examination program accurately assesses student failure to demonstrate competence. Methods. A progress examination program aligned with each grade level was locally developed and administered annually to 289 PharmD students in the spring of their first year – fourth year. Correlations and linear regressions were performed to compare the examination scores to performance on national licensing examinations and cumulative didactic grade point average (GPA). Odds ratio analysis was run to determine the ability of the passing scores of the progress examination to identify students at increased risk of failing to graduate on time, earn a GPA below 3.0, and fail the licensing examinations on their first attempt. Results. Progress examination scores were strongly correlated to GPA and national licensing examination scores and weakly correlated to jurisprudence examination scores. Regression analysis indicated a significant linear relationship between examination scores and both GPA and the licensing examinations. Students who performed poorly on the progress examinations were more likely fail the national licensing examination, more likely to fail to graduate on time, and more likely to earn a cumulative didactic GPA below 3.0. Conclusions. The second-year examination program strongly predicts students at risk for failure to graduate on time or achieve a GPA below 3.0, while all four examinations identify students at risk of failing the national licensing examination on their first attempt. PMID:27899831

  9. Evidence of Criterion Validity for One Pharmacy School's Progress Examination Program.

    PubMed

    Alston, Greg L; Haltom, Wes R

    2016-10-25

    Objective. To provide evidence that the progress examination program accurately assesses student failure to demonstrate competence. Methods. A progress examination program aligned with each grade level was locally developed and administered annually to 289 PharmD students in the spring of their first year - fourth year. Correlations and linear regressions were performed to compare the examination scores to performance on national licensing examinations and cumulative didactic grade point average (GPA). Odds ratio analysis was run to determine the ability of the passing scores of the progress examination to identify students at increased risk of failing to graduate on time, earn a GPA below 3.0, and fail the licensing examinations on their first attempt. Results. Progress examination scores were strongly correlated to GPA and national licensing examination scores and weakly correlated to jurisprudence examination scores. Regression analysis indicated a significant linear relationship between examination scores and both GPA and the licensing examinations. Students who performed poorly on the progress examinations were more likely fail the national licensing examination, more likely to fail to graduate on time, and more likely to earn a cumulative didactic GPA below 3.0. Conclusions. The second-year examination program strongly predicts students at risk for failure to graduate on time or achieve a GPA below 3.0, while all four examinations identify students at risk of failing the national licensing examination on their first attempt.

  10. Fossil Energy Program Annual Progress Report for the Period April 1, 2000 through March 31, 2001

    SciTech Connect

    Judkins, RR

    2001-06-14

    This report covers progress made at Oak Ridge National Laboratory (ORNL) on research and development projects that contribute to the advancement of fossil energy technologies. Projects on the ORNL Fossil Energy Program are supported by the U.S. Department of Energy (DOE) Office of Fossil Energy, the DOE National Energy Technology Laboratory (NETL), the DOE Fossil Energy Clean Coal Technology (CCT) Program, the DOE National Petroleum Technology Office, and the DOE Fossil Energy Office of Strategic Petroleum Reserve (SPR). The ORNL Fossil Energy Program research and development activities cover the areas of coal, clean coal technology, gas, petroleum, and support to the SPR. An important part of the Fossil Energy Program is technical management of all activities on the DOE Fossil Energy Advanced Research (AR) Materials Program. The AR Materials Program involves research at other DOE and government laboratories, at universities, and at industrial organizations.

  11. Gas-cooled fast reactor program. Progress report, January 1, 1980-June 30, 1981

    SciTech Connect

    Kasten, P.R.

    1981-09-01

    Since the national Gas-Cooled Fast Breeder Reactor Program has been terminated, this document is the last progress report until reinstatement. It is divided into three sections: Core Flow Test Loop, GCFR shielding and physics, and GCFR pressure vessel and closure studies. (DLC)

  12. Student Progress and Goal Attainment Report: Federally-Funded ABE Programs in California, 1998-99.

    ERIC Educational Resources Information Center

    Johnston, Dennis; Van Heertum, Rich; Evans, Andrew; Cloney, Matthew; Ochoa, Glen; Rickard, Pat; Coogan, Lori; Merry, Teri; Miller, Jennifer

    The report presents the Adult Basic Education (ABE) 321/326 California learning progress and goal attainment data for fiscal year 1998-99. Chapter 1 introduces an overview of adult basic education in California and contains information about ABE 321/326 federal programs and the Comprehensive Adult Student Assessment System (CASES). It discusses…

  13. All over the Map: A Progress Report on the State Children's Health Insurance Program (CHIP).

    ERIC Educational Resources Information Center

    Edmunds, Margo; Teitelbaum, Martha; Gleason, Cassy

    The State Children's Health Insurance Program (CHIP) was designed in 1997 to support working families by providing affordable, quality health coverage for their children in an efficient, effective, and coordinated way. This report examines the progress made in implementing CHIP nationwide. Information sources included the following: (1) federal…

  14. Progress report for the Monte-Carlo gamma-ray spectrum simulation program BSIMUL

    NASA Technical Reports Server (NTRS)

    Haywood, S. E.; Rester, A. C., Jr.

    1996-01-01

    The progress made during 1995 on the Monte-Carlo gamma-ray spectrum simulation program BSIMUL is discussed. Several features have been added, including the ability to model shields that are tapered cylinders. Several simulations were made on the Near Earth Asteroid Rendezvous detector.

  15. Electric and hybrid vehicle program site operator program. Quarterly progress report, January 1995--March 1995

    SciTech Connect

    Kiser, D.M.; Brown, H.L.

    1995-08-01

    The Site Operator Program was initially established by the Department of Energy (DOE) to incorporate the electric vehicle activities dictated by the Electric and Hybrid Vehicle Research, Development and Demonstration Act of 1976. In the ensuing years, the Program has evolved in response to new legislation and interests. The Program currently includes twelve sites located in diverse geographic, metrologic, and metropolitan areas across the United States. Information is shared reciprocally with a thirteenth site, not under Program contract. The vehicles are operator-owned. The Mission Statement of the Site Operator Program includes three major activities: (1) Advancement of electric vehicle technologies; (2) Development of infrastructure elements necessary to support significant electric vehicle use; and (3) Increasing the awareness and acceptance of electric vehicles (EVs) by the public. The current participants in the Site Operator Program are shown. Table 1 indicates the EVs in each of the Site Operator fleets. Table 2 provides baseline information on several EVs currently in use by the Site Operators, or which have evolved to the point that they may be introduced in the near future. The Program is currently managed by personnel of the Electric and Hybrid Vehicle Program at the Idaho National Engineering Laboratory (INEL). The current principal management functions include: Coordination of Site Operator efforts in the areas of public awareness and infrastructure development (program-related meetings, and educational presentations).

  16. U.S. Geological Survey heavy metals program progress report 1968 - Field studies

    USGS Publications Warehouse

    ,

    1969-01-01

    The Heavy Metals program of the U.S. Geological Survey and the U.S. Bureau of Mines began in mid-1966 and thus at the end of calendar year 1968 was halfway through its third year. This progress report summarizes field studies carried out under the Geological Survey's part of the program during 1968. Topical studies for 1968 are summarized in U.S. Geological Survey Circular 622. Background of the program and results during 1966 and 1967 were reported in U.S. Geological Survey Circular 560 and will not be further discussed herein.

  17. NRC review of passive reactor design certification testing programs: Overview, progress, and regulatory perspective

    SciTech Connect

    Levin, A.E.

    1995-09-01

    New reactor designs, employing passive safety systems, are currently under development by reactor vendors for certification under the U.S. Nuclear Regulatory Commission`s (NRC`s) design certification rule. The vendors have established testing programs to support the certification of the passive designs, to meet regulatory requirements for demonstration of passive safety system performance. The NRC has, therefore, developed a process for the review of the vendors` testing programs and for incorporation of the results of those reviews into the safety evaluations for the passive plants. This paper discusses progress in the test program reviews, and also addresses unique regulatory aspects of those reviews.

  18. Recent progress and concerns regarding the Japanese immunization program: addressing the "vaccine gap".

    PubMed

    Saitoh, Akihiko; Okabe, Nobuhiko

    2014-07-23

    Recent progress in the Japanese immunization program has partially closed the "vaccine gap," i.e., the deficiencies in that program relative to immunization programs in other developed countries. During the last several years, seven new vaccines (12 new products, excluding influenza vaccines) have been introduced in Japan. Five of these new vaccines are produced outside Japan and four are now included as routine vaccines in the National Immunization Program, which is a new development in the licensing and financial support of imported vaccines. However, along with this progress, important concerns have arisen regarding the Japanese immunization program. A rubella epidemic among adults, in 2012-2013, resulted in more than 40 cases of congenital rubella syndrome as of March 2014. In addition, the temporary withdrawal of the active governmental recommendation for human papilloma virus vaccines, in 2013-2014, highlighted challenges in the current Japanese immunization system. Furthermore, some important vaccines - including vaccines for hepatitis B virus, mumps, varicella, and rotavirus - are still not included in the National Immunization Program and have been categorized as voluntary vaccines since their introduction. The possibility of their inclusion in the National Immunization Program remains a matter for discussion. We hope that future initiatives will further address the vaccine gap and protect Japanese children from vaccine-preventable diseases.

  19. How to Make Our Schools Healthy: Healthy Schools Program. Program Results Progress Report

    ERIC Educational Resources Information Center

    Brown, Michael H.

    2012-01-01

    The Healthy Schools Program provides technical assistance to help schools engage administrators, teachers, parents and vendors in increasing access to physical activity and healthier foods for students and staff. Current grants run to September 2013. The program addresses two policy priorities of the Childhood Obesity team: (1) Ensure that all…

  20. Congenital disseminated tufted angioma.

    PubMed

    Wang, Lei; Liu, Ling; Wang, Gang; Gao, Tianwen

    2013-04-01

    Tufted angioma represents a rare vascular tumor that can develop in children and young adults. It usually presents as solitary plaque or large tumor on the extremities, trunk or other anatomic sites. Histopathologically, it is characterized by proliferation of closely packed capillaries in the dermis in a 'cannonball' distribution. We described a 2-month-old child who developed widespread disseminated red papules since her birth. Eight lesions were excised for histopathology, seven of which showed typical cannonball-like distribution of proliferative capillaries, characteristic of tufted angioma, and one on the hand which showed focal disseminated proliferation of endothelial cells. Immunohistochemistry showed focal D2-40 positivity in one lesion and was negative in the other seven. Expression of Prox1 and Glut-1 was negative in all lesions. This case represented a disseminated form of tufted angioma.

  1. Progressive simulation-based program for training cardiac surgery-related skills.

    PubMed

    Cristancho, Sayra; Moussa, Fuad; Monclou, Alex; Moncayo, Camilo; Rueda, Claudia; Dubrowski, Adam

    2011-01-01

    Off Pump Coronary Artery Bypass (OPCAB) surgery is a strategy for revascularizing diseased coronary arteries without cardiopulmonary bypass. The complete operation can be deconstructed into individual tasks and subtasks that are ideal for creating simulation modules. Recently, we have developed a modular mechanical beating-heart OPCAB simulator for use in learner-centered training. In the present study, we describe the design of a progressive, simulation-augmented training program for OPCAB surgery. In particular, we a) define need-driven education and training goals, b) create simulation scenarios with progressive difficulty to specifically address these goals, and c) design corresponding assessment tools for both formative and summative purposes.

  2. Integration of progressive hedging and dual decomposition in stochastic integer programs

    DOE PAGES

    Watson, Jean -Paul; Guo, Ge; Hackebeil, Gabriel; ...

    2015-04-07

    We present a method for integrating the Progressive Hedging (PH) algorithm and the Dual Decomposition (DD) algorithm of Carøe and Schultz for stochastic mixed-integer programs. Based on the correspondence between lower bounds obtained with PH and DD, a method to transform weights from PH to Lagrange multipliers in DD is found. Fast progress in early iterations of PH speeds up convergence of DD to an exact solution. As a result, we report computational results on server location and unit commitment instances.

  3. Electric and Hybrid Vehicle Program: Site Operation Program. Quarterly progress report, July--September 1995

    SciTech Connect

    Francfort, J.; Bassett, R.R.; Briasco, S.

    1995-12-01

    The Site Operator Program has evolved substantially since its inception in response to the Electric Vehicle Research and Demonstration Act of 1976. In its original form, a commercialization effort was intended but this was not feasible for lack of vehicle suppliers and infrastructure. Nonetheless, with DOE sponsorship and technical participation, a few results (primarily operating experience and data) were forthcoming. The current Program comprises eleven sites and over 200 vehicles, of which about 50 are latest generation vehicles. DOE partially funds the Program participant expenditures and the INEL receives operating and maintenance data for the DOE-owned, and participant-owned or monitored vehicles, as well as Program reports. As noted elsewhere in this report, participants represent several widely differing categories: electric utilities, academic institutions, and federal agencies. While both the utilities and the academic institutions tend to establish beneficial relationships with the industrial community.

  4. Disseminated Blastomycosis Mimicking Malignancy.

    PubMed

    Hsu, Jennifer L; Tjarks, B Joel; Berg, Aaron; Oliver, Tony

    2017-04-01

    Blastomycosis is an endemic fungal infection commonly found within the Mississippi and Ohio River basins and Great Lakes region. While patients typically present with acute pneumonia, Blastomyces dermatitidis has the potential to spread hematogenously, resulting in disseminated infection of multiple organs. In this report, we describe a 57-year-old male with disseminated blastomycosis acquired in South Dakota. The diagnostic evaluation was confounded by concern for malignancy given the involvement of multiple locations, including brain, lungs, adrenal glands, and testes. Despite aggressive therapy with amphotericin B, the patient succumbed to this infection. Copyright© South Dakota State Medical Association.

  5. Disseminated cutaneous sporotrichosis.

    PubMed

    Chang, Shurong; Hersh, Andrew M; Naughton, Greg; Mullins, Kevin; Fung, Maxwell A; Sharon, Victoria R

    2013-11-15

    The dimorphic fungus Sporothrix schenckii commonly causes localized cutaneous disease with lymphocutaneous distribution. However, disseminated sporotrichosis occurs predominantly in immunocompromised patients. We report a case of disseminated cutaneous sporotrichosis in a patient with newly diagnosed HIV with a CD4 count of 208. The patient presented with multiple cutaneous and subcutaneous nodules as well as fever and malaise. Tissue culture and skin biopsy confirmed the diagnosis of sporotrichosis. He was started on itraconazole 200mg twice a day with rapid resolution of fever along with cessation of the development of new lesions.

  6. Semiannual progress report for the Idaho Geothermal Program, October 1, 1980 to March 31, 1981

    SciTech Connect

    Parker, J.T.; Smith, C.J.

    1981-09-01

    Modifications incorporated in the 5-MW Pilot Power Plant at Raft River Geothermal Test Site, system operational testing and maintenance and activities at that plant, and the water treatment program's corrosion studies are summarized. Progress is reported on performance tests of the ORNL condenser in the Prototype Power Plant, checkout of the direct contact heat exchanger, and modification of that plant. The progress of testing and continuing studies of direct-contact heat exchangers is reported - including the liquid-liquid direct contact heat exchanger, primary heat exchanger, sieve tray preheater, multiple-purpose apparatus, and packed bed studies and tests. Effects of production-injection tests at Raft River on monitor wells are summarized. Monitoring activities and studies of the environmental program at Raft River are described and plans of two successful proposers under the User-Coupled Confirmation Drilling Program are summarized. Investigation of costs for three aspects of direct use of hydrothermal energy is reported. Progress is reported on the Marketing Assistance Program, through which technical information and assistance are provided to potential users and developers of geothermal resources.

  7. Surface Gasification Materials Program. Semiannual progress report for the period ending September 30, 1982

    SciTech Connect

    Not Available

    1982-12-01

    The objective of the Surface Gasification Materials Program is to conduct research and development on materials for application to the specific needs of coal gasification systems. The Program is divided into two subprograms: (1) the Gasification Systems Fabrication Technology Program and (2) the Materials Application and Development Program. The purpose of the Gasification Systems Fabrication Technology Program is to evaluate innovative fabrication methods which have the potential to lower costs and improve reliability and safety for gasifier vessels and components. The purpose of the Materials Application and Development Program is to conduct engineering-scale development and application of materials for coal gasification systems to ensure that the materials of construction for pilot plants and future large-scale plants can be properly selected and specified. The Morgantown Energy Technology Center (METC), in its lead role for gasification projects, is responsible for ensuring that the Surface Gasification Materials Program is responsive to the needs for gasification systems. Under its lead role for fossil energy materials, the Oak Ridge Operations Office (ORO), is responsible for the planning, implementation, and management of the program in accordance with guidance received from METC. The ORNL Fossil Energy Materials Program Office compiles and issues this combined semiannual progress report from camera-ready copies submitted by each of the participating organizations.

  8. Annual Program Progress Report under DOE/PHRI Cooperative Agreement: (July 1, 2001-June 30, 2002)

    SciTech Connect

    Palafox, Neal A., MD, MPH

    2002-07-31

    OAK B188 DOE/PHRI Special Medical Care Program in the Republic of the Marshall Islands (RMI)Annual Program Progress Report. The DOE Marshall Islands Medical Program continued, in this it's 48th year, to provide medical surveillance for the exposed population from Rongelap and Utrik and the additional DOE patients. The program was inaugurated in 1954 by the Atomic Energy Commission following the exposure of Marshallese to fallout from a nuclear test (Castle Bravo) at Bikini Atoll. This year marks the fourth year in which the program has been carried out by PHRI under a cooperative agreement with DOE. The DOERHRI Special Medical Care Program, awarded the cooperative agreement on August 28, 1998, commenced its health care program on January 15, 1999, on Kwajalein and January 22, 1999, on Majuro. This report details the program for the July 1, 2001, through the June 30, 2002, period. The program provides year-round, on-site medical care to the DOE patient population residing in the Republic of the Marshall Islands (RMI) and annual examinations to those patients living in Hawaii and on the Continental U.S.

  9. Federal assistance program. Quarterly project progress report, January 1998--March 1998

    SciTech Connect

    1998-04-01

    This report summarizes geothermal technical assistance, R&D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the second quarter of FY-98-98 (January-March, 1998). It describes 268 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include requests for general information including maps and material for high school debates, and material on geothermal heat pumps, resource and well data, spacing heating and cooling, greenhouses, aquaculture, equipment, district heating, resorts and spas, industrial applications, electric power and snow melting. Research activities include work on model construction specifications for line shaft submersible pumps and plate heat exchangers and a comprehensive aquaculture developer package. The revised Geothermal Direct Use Engineering and Design Guidebooks was completed, published and is available for distribution. Outreach activities include the publication of the Quarterly Bulletin (Vol. 19, No. 1) which was devoted entirely to geothermal equipment, dissemination of information mainly through mailings of publications, tours of local geothermal uses, geothermal library acquisitions and use, participation in workshops, short courses and technical meetings by the staff, and progress monitor reports on geothermal activities.

  10. Environmental Management Science Program awards. Fiscal year 1997 annual progress report

    SciTech Connect

    Simmons, A.; Benner, W.H.; DePaolo, D.J.; Faybishenko, B.; Majer, E.L.; Pallavicini, M.; Russo, R.E.; Shultz, P.G.; Wan, J.

    1997-10-01

    Lawrence Berkeley National Laboratory was awarded eight Environmental Management Science Program (EMSP) research grants in Fiscal Year 1996. This report summarizes the progress of each grant in addressing significant DOE site cleanup issues after completion of the first year of research. The technical progress made to date in each of the research projects is described in greater detail in individual progress reports. The focus of the research projects covers a diversity of areas relevant to site cleanup, including bioremediation, health effects, characterization, and mixed waste. Some of the projects cut across a number of focus areas. Three of the projects are directed toward characterization and monitoring at the Idaho National Engineering and Environmental Laboratory, as a test case for application to other sites.

  11. CE: Original Research: Creating an Evidence-Based Progression for Clinical Advancement Programs.

    PubMed

    Burke, Kathleen G; Johnson, Tonya; Sites, Christine; Barnsteiner, Jane

    2017-05-01

    : Background: The Institute of Medicine (IOM) and the Quality and Safety Education for Nurses (QSEN) project have identified six nursing competencies and supported their integration into undergraduate and graduate nursing curricula nationwide. But integration of those competencies into clinical practice has been limited, and evidence for the progression of competency proficiency within clinical advancement programs is scant. Using an evidence-based approach and building on the competencies identified by the IOM and QSEN, a team of experts at an academic health system developed eight competency domains and 186 related knowledge, skills, and attitudes (KSAs) for professional nursing practice. The aim of our study was to validate the eight identified competencies and 186 related KSAs and determine their developmental progression within a clinical advancement program. Using the Delphi technique, nursing leadership validated the newly identified competency domains and KSAs as essential to practice. Clinical experts from 13 Magnet-designated hospitals with clinical advancement programs then participated in Delphi rounds aimed at reaching consensus on the developmental progression of the 186 KSAs through four levels of clinical advancement. Two Delphi rounds resulted in consensus by the expert participants. All eight competency domains were determined to be essential at all four levels of clinical practice. At the novice level of practice, the experts identified a greater number of KSAs in the domains of safety and patient- and family-centered care. At more advanced practice levels, the experts identified a greater number of KSAs in the domains of professionalism, teamwork, technology and informatics, and continuous quality improvement. Incorporating the eight competency domains and the 186 KSAs into a framework for clinical advancement programs will likely result in more clearly defined role expectations; enhance accountability; and elevate and promote nursing practice

  12. Disseminated Balamuthia mandrillaris Infection

    PubMed Central

    Shah, Neil; Almira-Suarez, M. I.; Reese, Jennifer M.; Hoke, George M.; Mandell, James W.; Roy, Sharon L.; Visvesvara, Govinda

    2015-01-01

    Balamuthia mandrillaris is a rare cause of human infection, but when infections do occur, they result in high rates of morbidity and mortality. A case of disseminated Balamuthia infection is presented. Early diagnosis and initiation of recommended therapy are essential for increased chances of successful outcomes. PMID:26135864

  13. Seasonal thermal energy storage program. Progress report, January 1980-December 1980

    SciTech Connect

    Minor, J.E.

    1981-05-01

    The objectives of the Seasonal Thermal Energy Storage (STES) Program is to demonstrate the economic storage and retrieval of energy on a seasonal basis, using heat or cold available from waste sources or other sources during a surplus period to reduce peak period demand, reduce electric utilities peaking problems, and contribute to the establishment of favorable economics for district heating and cooling systems for commercialization of the technology. Aquifers, ponds, earth, and lakes have potential for seasonal storage. The initial thrust of the STES Program is toward utilization of ground-water systems (aquifers) for thermal energy storage. Program plans for meeting these objectives, the development of demonstration programs, and progress in assessing the technical, economic, legal, and environmental impacts of thermal energy storage are described. (LCL)

  14. Extremely Low Frequency (ELF) Communications System Ecological Monitoring Program: Summary of 1983 progress

    NASA Astrophysics Data System (ADS)

    Zapotosky, J.; Abromovage, M. M.; Enk, J. O.

    1984-07-01

    A long-term program for studying possible effects from operation of the Navy's ELF Communication System is being conducted on biota and ecosystems components in northwestern Wisconsin and the Upper Peninsula of Michigan. Sixteen general types of organisms from three major ecosystems in the ELF System are being examined. Formulation of an ELF Ecological Monitoring Program was completed in early 1982 by the Department of the Navy. Monitoring studies were selected through a peer-reviewed, competitive bidding process in mid-1982 and studies were initiated in the late summer. Major activities of the program during 1983 consisted of characterization of critical aspects of each study, collection of data to validate assumptions made in proposals, and selection of study sites. Progress is summarized for the 10 projects that comprise the Program.

  15. Fossil Energy Program semiannual progress report for April 1992-- September 1992

    SciTech Connect

    Judkins, R.R.

    1992-12-01

    This report covers progress made during the period April 1, 1992, through September 30, 1992, for research and development projects that contribute to the advancement of various fossil energy technologies. Projects on the Fossil Energy Program are supported by the DOE Office of Fossil Energy, the DOE Morgantown Energy Technology Center, the DOE Pittsburgh Energy Technology Center, the DOE Fossil Energy Clean Coal Technology Program, the DOE Office of Basic Energy Sciences, the DOE Fossil Energy Office of Petroleum Reserves, the DOE Fossil Energy Office of Naval Petroleum and Oil Shale Reserves, and the US Agency for International Development.

  16. Geothermal Energy R&D Program Annual Progress Report Fiscal Year 1993

    SciTech Connect

    1994-04-01

    In this report, the DOE Geothermal Program activities were split between Core Research and Industrial Development. The technical areas covered are: Exploration Technology, Drilling Technology, Reservoir Technology (including Hot Dry Rock Research and The Geyser Cooperation), and Conversion Technology (power plants, materials, and direct use/direct heat). Work to design the Lake County effluent pipeline to help recharge The Geysers shows up here for the first time. This Progress Report is another of the documents that are reasonable starting points in understanding many of the details of the DOE Geothermal Program. (DJE 2005)

  17. [Experimental and theoretical plasma physics program]. Technical progress [in FY 1981

    SciTech Connect

    Griem, H.

    1981-12-31

    In recent years, members of the Maryland Theory Group have made significant contributions to the national fusion theory programs and in many cases these theoretical development helped to interpret experimental results and to design new experimental programs. In the following, the authors summarize the technical progress in five major areas: (1) rf interaction with plasmas including wave propagation, rf heating, rf induced runaways and current drive; (2) spheromak -- formation, equilibrium, and stability; (3) stability of nonaxisymmetric systems (EBT, mirror, etc.); (4) stability theory of toroidal plasmas -- tokamak, RFP, etc.; and (5) nonlinear theory.

  18. Fossil Energy Program semiannual progress report for October 1992 through March 1993

    SciTech Connect

    Judkins, R.R.

    1993-07-01

    This report covers progress made during the period October 1, 1992, through March 31, 1993, for research and development projects that contribute to the advancement of various fossil energy technologies. Projects on the Fossil Energy Program are supported by the DOE Office of Fossil Energy, the DOE Morgantown Energy Technology Center, the DOE Pittsburgh Energy Technology Center, the DOE Fossil Energy Clean Coal Technology Program, the DOE Fossil Energy Office of Petroleum Reserves, and the US Agency for International Development. In particular, projects related to materials and coal combustion, environmental analysis, and bioconversion are described.

  19. [Experimental and theoretical plasma physics program]. [Final progress report, 1982--1983

    SciTech Connect

    Griem, H.

    1983-12-31

    In recent years, members of the Maryland Theory Group have made significant contributions to the national fusion theory programs, and, in many cases, these theoretical developments helped to interpret experimental results and to design new experimental programs. In the following, the authors summarize the technical progress in five major areas: (1) RF interaction with plasmas including wave propagation and RF heating, (2) spheromak formation, equilibrium, and stability; (3) stability of nonaxisymmetric systems (EBT, mirrors, etc.); (4) stability theory of toroidal plasmas (tokamak, RFP, etc); and (5) nonlinear theory.

  20. Fossil Energy Program semiannual progress report for April 1992-- September 1992

    SciTech Connect

    Judkins, R.R.

    1992-12-01

    This report covers progress made during the period April 1, 1992, through September 30, 1992, for research and development projects that contribute to the advancement of various fossil energy technologies. Projects on the Fossil Energy Program are supported by the DOE Office of Fossil Energy, the DOE Morgantown Energy Technology Center, the DOE Pittsburgh Energy Technology Center, the DOE Fossil Energy Clean Coal Technology Program, the DOE Office of Basic Energy Sciences, the DOE Fossil Energy Office of Petroleum Reserves, the DOE Fossil Energy Office of Naval Petroleum and Oil Shale Reserves, and the US Agency for International Development.

  1. The Energy-Related Inventions Program: A decade of commercial progress

    SciTech Connect

    Brown, M.A.; Franchuk, C.A.; Wilson, C.R.

    1991-12-01

    This report provides information on the recent commercial progress of inventions supported by the US Department of Energy`s Energy-Related Inventions Programs (ERIP). It describes the results of the latest in a series of ERIP evaluation projects that have been completed since 1980. It focuses on the economic impacts of the program, notably sales and employment benefits. The period of interest is 1980 through 1990. The evaluation is based on data collected through mail and telephone surveying of 143 participants in the Program. As of October 1989, a total of 486 inventions were recommended to DOE by the National Institute for Standards and Technology, which screens all submitted inventions in terms of technical merit, potential for commercial success, and potential energy impact. By the end of 1990, at least 109 of these inventions had entered the market, generating total cumulative sales of more than $500 million. With $25.7 million in grants awarded from 1975 through 1990, and $63.1 million in program appropriations over the same period, ERIP has generated a 20:1 return in terms of sales values to grants, and an 8:1 return in sales versus program appropriations. It is estimated that 25% of all ERIP inventions had achieved sales by the end of 1990. While it is difficult to make exact comparisons between these percentages and other indicators of the success rates of technological innovations as a whole, the ERIP figures remain impressive. The commercial progress of spin-off technologies is also documented.

  2. The Energy-Related Inventions Program: A decade of commercial progress

    SciTech Connect

    Brown, M.A.; Franchuk, C.A. ); Wilson, C.R. )

    1991-12-01

    This report provides information on the recent commercial progress of inventions supported by the US Department of Energy's Energy-Related Inventions Programs (ERIP). It describes the results of the latest in a series of ERIP evaluation projects that have been completed since 1980. It focuses on the economic impacts of the program, notably sales and employment benefits. The period of interest is 1980 through 1990. The evaluation is based on data collected through mail and telephone surveying of 143 participants in the Program. As of October 1989, a total of 486 inventions were recommended to DOE by the National Institute for Standards and Technology, which screens all submitted inventions in terms of technical merit, potential for commercial success, and potential energy impact. By the end of 1990, at least 109 of these inventions had entered the market, generating total cumulative sales of more than $500 million. With $25.7 million in grants awarded from 1975 through 1990, and $63.1 million in program appropriations over the same period, ERIP has generated a 20:1 return in terms of sales values to grants, and an 8:1 return in sales versus program appropriations. It is estimated that 25% of all ERIP inventions had achieved sales by the end of 1990. While it is difficult to make exact comparisons between these percentages and other indicators of the success rates of technological innovations as a whole, the ERIP figures remain impressive. The commercial progress of spin-off technologies is also documented.

  3. Technical progress in silicon sheet growth under DOE/JPL FSA program, 1975-1986

    NASA Technical Reports Server (NTRS)

    Kalejs, J. P.

    1986-01-01

    The technical progress made in the Silicon Sheet Growth Program during its 11 years was reviewed. At present, in 1986, only two of the original 9 techniques have survived to the start-up, pilot-plant stage in industry. These two techniques are the edge-defined, film-fed growth (EFG) technique that produces closed shape polygons, and the WEB dendritic technique that produces single ribbons. Both the status and future concerns of the EFG and WEB techniques were discussed.

  4. Consolidated Fuel Reprocessing Program. Progress report for period, April 1-June 30, 1985

    SciTech Connect

    Not Available

    1985-08-01

    All research and development on civilian power reactor fuel reprocessing in the United States is managed under the Consolidated Fuel Reprocessing Program (CFRP) centered at Oak Ridge National Laboratory (ORNL). Technical progress is reported in overview fashion for the following: (1) process and engineering R and D; (2) engineering systems; (3) integrated equipment test facility operations; (4) strategic planning and analysis; (5) breeder reprocessing engineering test project; and HTGR fuel reprocessing.

  5. Short-rotation woody-crops program. Quarterly progress report for period ending May 31, 1981

    SciTech Connect

    Cushman, J.H.; Ranney, J.W.

    1982-04-01

    Progress of twenty projects in the Short Rotation Woody Crops Program is summarized for the period March 1 through May 31, 1981. Individual quarterly reports included from each of the projects discuss accomplishments within specific project objectives and identify recent papers and publications resulting from the research. The major project activities are species screening and genetic selection, stand establishment and cultural treatment, and harvest, collection, transportation, and storage.

  6. Cassini RTG Program monthly technical progress report, July 28--August 24, 1997

    SciTech Connect

    1997-09-24

    The technical progress achieved during this period is described. This report is organized by program task structure: (1) spacecraft and integration liaison; (2) engineering support; (3) safety; (4) qualified unicouple production; (5) ETG fabrication, assembly, and test; (6) ground support equipment (GSE); (7) RTG shipping and launch support; (8) designs, reviews, and mission applications; (9) project management, quality assurance, reliability, contract changes, CAGO acquisition (operating funds), and CAGO maintenance and repair; and (10) CAGO acquisition (capital funds).

  7. Cassini RTG Program. Monthly technical progress report, October 30--November 26, 1995

    SciTech Connect

    1995-12-24

    The technical progress achieved during the period 30 October through 26 November, 1995 is described herein. This report is organized by program task structure: (1) spacecraft integration and liaison; (2) engineering support; (3) safety; (4) qualified unicouple production; (5) ETG fabrication, assembly, and test; (6) ground support equipment (GSE); (7) RTG shipping and launch support; (8) designs, reviews, and mission applications; (9) project management, quality assurance, reliability, contract changes, CAGO acquisition (operating funds), and GACO maintenance and repair; and CAGO acquisition (capital funds).

  8. Cassini RTG Program. Monthly technical progress report, October 2--October 29, 1995

    SciTech Connect

    1995-11-24

    The technical progress achieved during the period 2 October through 29 October, 1995 is described herein. This report is organized by program task structure: (1) spacecraft integration and liaison; (2) engineering support; (3) safety; (4) qualified unicouple production; (5) ETG fabrication, assembly, and test; (6) ground support equipment (GSE); (7) RTG shipping and launch support; (8) designs, reviews, and mission applications; (9) project management, quality assurance, reliability, contract changes, CAGO acquisition (operating funds), and GACO maintenance and repair; and CAGO acquisition (capital funds).

  9. University Research Programs in Robotics annual technical progress report, June 1, 1994--May 31, 1995

    SciTech Connect

    1995-06-01

    The University of Florida supported three technical areas within the US Department of Energy`s Robotics Technology Development Program (RTDP) during this project period: Tank Waste Retrieval (TWR) Analysis Automation (CAA), and Cross-Cutting and Advanced Technology (CC&AT). This reports the technical progress made on the tasks for each of these areas. Detailed reports will be sent to the RTDP coordinator and the project area coordinators at the end of the project period.

  10. Review of progress in the Canadian nuclear fuel waste management program

    SciTech Connect

    Lyon, R.B.; Johnson, L.H.

    1986-01-01

    The Canadian Nuclear Fuel Waste Management Program is reviewed, illustrating the progress that has been made in assessing the concept of disposal of nuclear fuel waste in plutonic rock of the Canadian Shield. Research is being conducted into used fuel storage and transportation, fuel waste immobilization, site characterization and selection methods, and performance assessment modelling. Details of achievements in these areas are outlined, and results of the most recent interim assessment are discussed.

  11. PROGRESSIVE CHOICE PROGRAMMING FOR DELINQUENOGENIC COMMUNITIES, PHASE II--VALIDATION OF THE BASIC LITERACY PROGRAM.

    ERIC Educational Resources Information Center

    Institute of Educational Research, Washington, DC.

    A HIGH SPEED, LOW COST SYSTEM OF TRAINING AND EDUCATION WHICH CAN PROVIDE LITERACY SKILLS, JOB SKILLS, AND ACADEMIC SKILLS TO MEMBERS OF DELINQUENOGENIC COMMUNITIES WAS SOUGHT. SHORT UNITS OF PROGRAMED MATERIAL REQUIRED A RESPONSE TO THE TEXT AFTER WHICH IT FEEDS BACK THE ADEQUACY AND RELEVANCY OF THE LEARNER'S RESPONSE. POST-READING SKILLS, BASIC…

  12. ESEA III Evaluation and Dissemination: An Assessment.

    ERIC Educational Resources Information Center

    Balyeat, Ralph R.; Norman, C. Douglas

    This study surveyed evaluation and dissemination/diffusion practices of ESEA III projects funded in the 1969 fiscal year, which projects are nearing the end of their operations as federally supported programs. The study attempted to discover if (1) the projects were evaluated in accordance with generally accepted procedures, (2) the project…

  13. Aberrant Splicing in Cancer: Mediators of Malignant Progression through an Imperfect Splice Program Shift.

    PubMed

    Luz, Felipe Andrés Cordero; Brígido, Paula Cristina; Moraes, Alberto Silva; Silva, Marcelo José Barbosa

    2017-01-01

    Although the efforts to understand the genetic basis of cancer allowed advances in diagnosis and therapy, little is known about other molecular bases. Splicing is a key event in gene expression, controlling the excision of introns decoded inside genes and being responsible for 80% of the proteome amplification through events of alternative splicing. Growing data from the last decade point to deregulation of splicing events as crucial in carcinogenesis and tumor progression. Several alterations in splicing events were observed in cancer, caused by either missexpression of or detrimental mutations in some splicing factors, and appear to be critical in carcinogenesis and key events during tumor progression. Notwithstanding, it is difficult to determine whether it is a cause or consequence of cancer and/or tumorigenesis. Most reviews focus on the generated isoforms of deregulated splicing pattern, while others mainly summarize deregulated splicing factors observed in cancer. In this review, events associated with carcinogenesis and tumor progression mainly, and epithelial-to-mesenchymal transition, which is also implicated in alternative splicing regulation, will be progressively discussed in the light of a new perspective, suggesting that splicing deregulation mediates cell reprogramming in tumor progression by an imperfect shift of the splice program. © 2016 S. Karger AG, Basel.

  14. Geothermal direct-heat utilization assistance. Quarterly project progress report, July 1996--September 1996. Federal Assistance Program

    SciTech Connect

    Lienau, P.

    1996-11-01

    This report summarizes geothermal technical assistance, R&D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the fourth quarter of FY-96. It describes 152 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include geothermal heat pumps, space heating, greenhouses, aquaculture, equipment, economics and resources. Research activities are summarized on greenhouse peaking. Outreach activities include the publication of a geothermal direct use Bulletin, dissemination of information, geothermal library, technical papers and seminars, and progress monitor reports on geothermal resources and utilization.

  15. Electric and Hybrid Vehicle Program; Site Operator Program. Quarterly progress report, October--December 1991

    SciTech Connect

    Warren, J.F.

    1992-01-01

    Activities during the first quarter centered around integrating the new participants into the program. A meeting of the Site Operators, in conjunction with the first meeting of the Electric Vehicle Users Task Force, was held in October. A second meeting of the Task Force was held in December. During these meetings the new contractual requirements were explained to the participants. The Site Operator Data Base was distributed and explained. The Site Operators will begin using the data base in December 1991 and will supply the operating and maintenance data to the INEL on a monthly basis. The Operators requested that they be able to have access to the data of the other Operators and it was agreed that they would be provided this on floppy disk monthly from the INEL. Presentations were made to the DOE sponsored Automotive Technology Development-Contractors Coordination Meeting in October. An overview of the program was given by EG&G. Representatives from Arizona Public Service, Texas A&M University, and York Technical College provided details of their programs and the results and future goals. Work was begun on commercializing the Versatile Data Acquisition System (VDAS). A Scope of Work has been written for a Cooperative Research and Development Agreement (CRADA) to be submitted to the USABC. If implemented, the CRADA will provide funds for the development and commercialization of the VDAS. Participants in the Site Operator Program will test prototypes of the system within their fleets, making the data available to the USABC and other interested organizations. The USABC will provide recommendations on the data to be collected. Major activities by the majority of the Operators were involved with the continued operation and demonstration of existing vehicles. In addition, several of the operators were involved in identifying and locating vehicles to be added to their fleets. A list of the vehicles in each Site Operator fleet is included as Appendix A to this report.

  16. 40 CFR 56.6 - Dissemination of policy and guidance.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 6 2014-07-01 2014-07-01 false Dissemination of policy and guidance. 56.6 Section 56.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGIONAL CONSISTENCY § 56.6 Dissemination of policy and guidance. The Assistant Administrators...

  17. 40 CFR 56.6 - Dissemination of policy and guidance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 5 2011-07-01 2011-07-01 false Dissemination of policy and guidance. 56.6 Section 56.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGIONAL CONSISTENCY § 56.6 Dissemination of policy and guidance. The Assistant Administrators of...

  18. Strengthening scientific verbal behavior: an experimental comparison of progressively prompted and unprompted programmed instruction and prose tutorials.

    PubMed

    Davis, Darrel R; Bostow, Darrel E; Heimisson, Gudmundur T

    2007-01-01

    Web-based software was used to deliver and record the effects of programmed instruction that progressively added formal prompts until attempts were successful, programmed instruction with one attempt, and prose tutorials. Error-contingent progressive prompting took significantly longer than programmed instruction and prose. Both forms of programmed instruction substantially increased the appropriate use of behavioral vocabulary during subsequent interpretive essays. These behavioral gains extended to a different setting, suggesting that more was being learned than simply how to answer programmed tutorial frames correctly.

  19. Extremely Low Frequency (ELF) communications system ecological monitoring program. Summary of 1984 progress

    NASA Astrophysics Data System (ADS)

    Zapotosky, J. E.

    1985-07-01

    A long-term program is being conducted to monitor for possible effects from the operation of the U.S. Navy's ELF Communications System to resident biota and their ecological relationships. Monitoring studies were selected through a peer-reviewed, competitive bidding process in mid-1982; studies were initiated in late summer of that year. Currently, 16 general types of organisms from three major ecosystems in the ELF Communications System are being examined. During 1984, the Program continued and extended those major activities initiated in 1983, consisting of site selection, the characterization of critical study aspects, and, to a lesser degree, the validation of assumptions made in the original proposals. Progress is summarized for the 11 projects that comprise the Program as well as for the support activities of IIT Research Institute.

  20. Fossil Energy Program semiannual progress report for October 1991--March 1992

    SciTech Connect

    Judkins, R.R.

    1992-11-01

    This report covers progress made during the period October 1, 1991, through March 31, 1992, for research and development projects that contribute to the advancement of various fossil energy technologies. Projects on the Fossil Energy Program are supported by the DOE Office of Fossil Energy, the DOE Morgantown Energy Technology Center, the DOE Pittsburgh Energy Technology Center, the DOE Fossil Energy Clean Coal Technology Program, the DOE Office of Basic Energy Sciences, the DOE Fossil Energy Office of Petroleum Reserves, the DOE Fossil Energy Naval Petroleum and Oil Shale Reserves, and the US Agency for International Development. The Fossil Energy Program organization chart is shown in the appendix. Topics discussed are under the following projects: materials research and developments; environmental analysis support; coal conversion development; coal combustion research; and fossil fuels supplies modeling and research.

  1. Heavy-section steel irradiation program. Progress report, October 1994--March 1995

    SciTech Connect

    Corwin, W.R.

    1995-10-01

    This document is the October 1994-March 1995 Progress Report for the Heavy Section Steel Irradiation Program. The report contains a summary of activities in each of the 14 tasks of the HSSI Program, including: (1) Program management, (2) Fracture toughness shifts in high-copper weldments, (3) Fracture toughness shifts in low upper-shelf welds, (4) Irradiation effects in a commercial low upper-shelf weld, (5) Irradiation effects on weld heat-affected zone and plate materials, (6) Annealing effects in low upper-shelf welds, (7) Microstructural analysis of radiation effects, (8) In-service irradiated and aged material evaluations, (9) Japanese power development reactor vessel steel examination, (10) fracture toughness curve shift method, (11) Special technical assistance, (12) Technical assistance for JCCCNRS, (13) Correlation monitor materials, and (14) Test reactor irradiation coordination. Selected papers have been indexed separately for inclusion in the Energy Science and Technology Database.

  2. On-board computer progress in development of A 310 flight testing program

    NASA Technical Reports Server (NTRS)

    Reau, P.

    1981-01-01

    Onboard computer progress in development of an Airbus A 310 flight testing program is described. Minicomputers were installed onboard three A 310 airplanes in 1979 in order to: (1) assure the flight safety by exercising a limit check of a given set of parameters; (2) improve the efficiency of flight tests and allow cost reduction; and (3) perform test analysis on an external basis by utilizing onboard flight types. The following program considerations are discussed: (1) conclusions based on simulation of an onboard computer system; (2) brief descriptions of A 310 airborne computer equipment, specifically the onboard universal calculator (CUB) consisting of a ROLM 1666 system and visualization system using an AFIGRAF CRT; (3) the ground system and flight information inputs; and (4) specifications and execution priorities for temporary and permanent programs.

  3. Fossil Energy Program semiannual progress report for April 1991 through September 1991

    SciTech Connect

    Judkins, R.R.

    1992-10-01

    This report covers progress made during the period April 1, 1991, through September 30, 1991, for research and development projects that contribute to the advancement of various fossil energy technologies. Projects on the Fossil Energy Program are supported by the DOE Office of Fossil Energy, the DOE Morgantown Energy Technology Center, the DOE Pittsburgh Energy Technology Center, the DOE Fossil Energy Clean Coal Technology Program, the DOE Fossil Energy Office of Petroleum Reserves, and the US Agency for International Development (USAID). The Fossil Energy Program organization chart is shown in the appendix. Project discussed are: materials research and development; environmental analysis support; coal conversion development; coal combustion research; fossil fuel supplies modeling and research; evaluations and assessments; and coal structure and chemistry.

  4. Fossil Energy Program semiannual progress report for October 1991--March 1992

    SciTech Connect

    Judkins, R.R.

    1992-11-01

    This report covers progress made during the period October 1, 1991, through March 31, 1992, for research and development projects that contribute to the advancement of various fossil energy technologies. Projects on the Fossil Energy Program are supported by the DOE Office of Fossil Energy, the DOE Morgantown Energy Technology Center, the DOE Pittsburgh Energy Technology Center, the DOE Fossil Energy Clean Coal Technology Program, the DOE Office of Basic Energy Sciences, the DOE Fossil Energy Office of Petroleum Reserves, the DOE Fossil Energy Naval Petroleum and Oil Shale Reserves, and the US Agency for International Development. The Fossil Energy Program organization chart is shown in the appendix. Topics discussed are under the following projects: materials research and developments; environmental analysis support; coal conversion development; coal combustion research; and fossil fuels supplies modeling and research.

  5. [Disseminated mycosis fungoides].

    PubMed

    Trope, B M; Schmidt, J M; de Oliveira Neto, A A; Pereira Júnior, A C; Marques, A de S; Ishida, C E; Azulay, R D

    1985-01-01

    A case of mycosis fungoides (MF) that began with cutaneous eritemato-papular lesions leading to death with neurological symptoms is reported. Cutaneous histophatology was typical to MF and the liquoric citology showed Sézary cells. Necropsy evidenced extra-cutaneous dissemination of the tumor involving lymphnodes, heart, digestive system, bladder, liver, bone marrow and leptomeninges. The uncommon clinical manifestations and evolution are discussed.

  6. Disseminated superficial actinic porokeratosis.

    PubMed

    Rouhani, Panta; Fischer, Max; Meehan, Shane; Pomeranz, Miriam Keltz

    2012-12-15

    Disseminated superficial actinic porokeratosis, which was described in 1966, is characterized by small, atrophic patches with distinctive keratin rims that occur on sun-exposed areas of the extremities, shoulders, and back. The diagnosis is based on the histopathologic finding of a cornoid lamella, absence of a granular layer, and often a thin epidermis. It is associated with exposure to ultraviolet radiation. Gene studies suggest a pathway defect in which several mutations in keratinocyte proliferation and differentiation lead to development of porokeratosis.

  7. Disseminated superficial porokeratosis.

    PubMed

    Brauer, Jeremy A; Mandal, Rajni; Walters, Ruth; Solomon, Gary; Kundu, Roopal V; Strober, Bruce E

    2010-11-15

    A 62-year-old woman with psoriasis and psoriatic arthritis presented for evaluation and treatment of a one-week history of pruritic, pink spots on her trunk and extremities. Several weeks prior, therapy with certolizumab pegol and methotrexate was started for her psoriatic arthritis. A biopsy specimen was consistent with the diagnosis of porokeratosis. Owing to the setting of immunosuppression and presence of symmetric pruritic lesions on non-sun exposed areas, the diagnosis of disseminated superficial porokeratosis was made.

  8. Nuclear medicine program progress report for quarter ending December 31, 1996

    SciTech Connect

    Knapp, F.F. Jr.; Beets, A.L.; Boll, R.; Luo, H.; McPherson, D.W.; Mirzadeh, S.

    1997-03-20

    In this report the authors describe the use of an effective method for concentration of the rhenium-188 bolus and the results of the first Phase 1 clinical studies for bone pain palliation with rhenium-188 obtained from the tungsten-188/rhenium-188 generator. Initial studies with therapeutic levels of Re-188-HEDP at the Clinic for Nuclear Medicine at the University of Bonn, Germany, have demonstrated the expected good metastatic uptake of Re-188-HEDP in four patients who presented with skeletal metastases from disseminated prostatic cancer with good pain palliation and minimal marrow suppression. In addition, skeletal metastatic targeting of tracer doses of Re-188(V)-DMSA has been evaluated in several patients with metastases from prostatic cancer at the Department of Nuclear Medicine at the Canterbury and Kent Hospital in Canterbury, England. In this report the authors also describe further studies with the E-(R,R)-IQNP ligand developed in the ORNL Nuclear Medicine Program as a potential imaging agent for detection of changes which may occur in the cerebral muscarinic-cholinergic receptors (mAChR) in Alzheimer`s and other diseases.

  9. Public information, dissemination, and behavior analysis

    PubMed Central

    Morris, Edward K.

    1985-01-01

    Behavior analysts have become increasingly concerned about inaccuracies and misconceptions in the public, educational, and professional information portraying their activities, but have done little to correct these views. The present paper has two purposes in this regard. First, the paper describes some of the conditions that have given rise to these concerns. Second, and more important, the paper surveys various procedures and programs for the dissemination of public information that may correct inaccuracies and misconceptions. Special consideration is also given to issues involving (a) the assessment of the problem, (b) the content and means of dissemination, (c) the possible contributions of behavior analysts to current misunderstandings, and (d) relationships between behavior analysts and the media. The dissemination of accurate and unbiased information constitutes an important new undertaking for behavior analysis. The future of the field may depend in part on such activity. PMID:22478623

  10. The RERTR (Reduced Enrichment Research and Test Reactor) Program: Progress and plans

    SciTech Connect

    Travelli, A.

    1987-01-01

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. After a brief summary of the results which the RERTR Program, in collaboration with its many international partners, had achieved by the end of 1986, the activities, results, and new developments which occurred in 1987 are reviewed. Irradiation of the second miniplate series, concentrating on U/sub 3/Si/sub 2/-Al and U/sub 3/Si-Al fuels, was completed and postirradiation examinations were performed on many of its miniplates. The whole-core ORR demonstration with U/sub 3/Si/sub 2/-Al fuel at 4.8 g U/cm/sup 3/ was completed at the end of March with excellent results and with 29 elements estimated to have reached at least 40% average burnup. Good progress was made in the area of LEU usage for the production of fission /sup 99/Mo, and in the coordination of safety evaluations related to LEU conversions of US university reactors. Planned activities include testing and demonstrating advanced fuels intended to allow use of reduced enrichment uranium in very-high-performance reactors. Two candidate fuels are U/sub 3/Si-Al with 19.75% enrichment and U/sub 3/Si/sub 2/-Al with 45% enrichment. Demonstration of these fuels will include irradiation of full-size elements and, possibly, a full-core demonstration. Achievement of the final program goals is still projected for 1990. This progress could not have been possible without the close international cooperation which has existed from the beginning, and which is essential to the ultimate success of the RERTR Program.

  11. Progress?

    NASA Astrophysics Data System (ADS)

    Scientists who were once protected by the hammer and sickle are now being bludgeoned with them, according to a report published in November by the American Association for the Advancement of Science (AAAS). Thousands of scientists, professors, and science teachers who had been affiliated with the communist regimes of Central and Eastern European nations are being purged from academic institutions under the premise of righting a perceived historical wrong.More than 3,000 scientists in Bulgaria, as well as 884 university professors and 10,000 teachers in the German state of Saxony, have lost their jobs in the past 5 years. Nearly 6% of all Czech faculty members also have been fired. The purges—which are more reminiscent of the communist past than of a democratic future—are the result of government-sanctioned programs to weed out public employees who may have received their positions due to their Communist affiliation.

  12. progressive problemshifts between different research programs in science education: A lakatosian perspective

    NASA Astrophysics Data System (ADS)

    Niaz, Mansoor

    Given the importance of epistemology and philosophy of science, the Lakatos (1970) methodology is particularly suited to evaluate competing research programs in science education. This article has two objectives: (a) to evaluate critically the interpretations of Gilbert and Swift (1985) and Rowell and Dawson (1989), and (b) to postulate a progressive problemshift between Piaget's epistemic subject and Pascual-Leone's metasubject. Regarding the Gilbert and Swift interpretation, it is concluded that the alternative conceptions movement at its present stage of development cannot explain the previous success of its rival (Piagetian school) nor supersede it by a further display of heuristic power as required by Lakatos. If we accept the Rowell and Dawson thesis it would amount to the postulation of Piagetian and integrated (Piagetian and schema) theories as rival research programs. It appears that the Rowell and Dawson approach would enrich Piagetian theory with descriptive content rather than explanatory constructs, and thus would not lead to a progressive problemshift. It is concluded that Pascual-Leone's theory extends Piaget's negative heuristic by introducing antecedent variables, and at the same time enriches the positive heuristic by introducing metasubjective task analysis, which leads to a progressive problemshift.

  13. The Glen Canyon Dam adaptive management program: progress and immediate challenges

    USGS Publications Warehouse

    Hamill, John F.; Melis, Theodore S.; Boon, Philip J.; Raven, Paul J.

    2012-01-01

    Adaptive management emerged as an important resource management strategy for major river systems in the United States (US) in the early 1990s. The Glen Canyon Dam Adaptive Management Program (‘the Program’) was formally established in 1997 to fulfill a statutory requirement in the 1992 Grand Canyon Protection Act (GCPA). The GCPA aimed to improve natural resource conditions in the Colorado River corridor in the Glen Canyon National Recreation Area and Grand Canyon National Park, Arizona that were affected by the Glen Canyon dam. The Program achieves this by using science and a variety of stakeholder perspectives to inform decisions about dam operations. Since the Program started the ecosystem is now much better understood and several biological and physical improvements have been achieved. These improvements include: (i) an estimated 50% increase in the adult population of endangered humpback chub (Gila cypha) between 2001 and 2008, following previous decline; (ii) a 90% decrease in non-native rainbow trout (Oncorhynchus mykiss), which are known to compete with and prey on native fish, as a result of removal experiments; and (iii) the widespread reappearance of sandbars in response to an experimental high-flow release of dam water in March 2008.Although substantial progress has been made, the Program faces several immediate challenges. These include: (i) defining specific, measurable objectives and desired future conditions for important natural, cultural and recreational attributes to inform science and management decisions; (ii) implementing structural and operational changes to improve collaboration among stakeholders; (iii) establishing a long-term experimental programme and management plan; and (iv) securing long-term funding for monitoring programmes to assess ecosystem and other responses to management actions. Addressing these challenges and building on recent progress will require strong and consistent leadership from the US Department of the Interior

  14. Review of geochemical reference sample programs since G-1 and W-1: progress to date and remaining challenges

    USGS Publications Warehouse

    Kane, J.S.

    1991-01-01

    A brief history of programs to develop geochemical reference samples and certified reference samples for use in geochemical analysis is presented. While progress has been made since G-1 and W-1 were issued, many challenges remain. ?? 1991.

  15. Coadminstration of L. major amastigote class I nuclease (rLmaCIN) with LPD nanoparticles delays the progression of skin lesion and the L. major dissemination to the spleen in BALB/c mice-based experimental setting.

    PubMed

    Fakhraee, Fatemeh; Badiee, Ali; Alavizadeh, Seyedeh Hoda; Jalali, Seyed Amir; Chavoshian, Omid; Khamesipour, Ali; Mahboudi, Fereidoun; Jaafari, Mahmoud Reza

    2016-07-01

    Human cutaneous leishmaniasis is a disease caused by eukaryotic single-celled Leishmania species, the developmental program of which relies upon blood-feeding adult female sand flies and their dominant mammal blood sources, namely wild rodents in area where human beings exert more or less transient activities. The recourse to model rodents - namely laboratory mice such as C57BL/6 mice - has allowed extracted the immune signatures that account for the healing of the transient cutaneous lesion that develops at the site where Leishmania major promastigotes were delivered. Indeed, if the latter mice are exposed to a second inoculum of L. major promastigotes, no lesion will develop in the secondary skin site remodeled as a niche for a low size intracellular L. major amastigote population. Moreover, IFN-γ dominates over IL-10 in the supernatant of cultures of PBMCs -prepared from blood sampled from human beings who healed from a cutaneous lesion- and incubated with L. major class I Nuclease LmaCIN, a protein highly expressed in the cell-cycling amastigote population which is dominant by macrophages. Altogether, these datasets were strong incentive to promote research aimed to design and monitor efficacy of L. major amastigote protein-based vaccines in pre-clinical settings. Using L. major enzyme class I nuclease (LmaCIN) expressed in the L. major cell-cycling amastigote population hosted by macrophages, BALB/c mice were immunized three times with either rLmaCIN plus LPD nanoparticles (LPD-rLmaCIN), or rLmaCIN-CpG DNA or free rLmaCIN and dextrose. The following parameters: footpad swelling, splenic L. major load, L. major binding IgGs and cytokine profiles of rLmaCIN- reactive T lymphocytes were then compared. Once coadminstered with LPD, rLmaCIN allow BALB/c mice to display delayed onset of skin lesion at the challenge inoculation site and delayed L. major dissemination from the challenged site to the spleen. Thus, the LPD-rLmaCIN is shown to display some promising

  16. Consolidated Fuel Reprocessing Program: Progress report for period October 1 to December 31, 1986

    SciTech Connect

    Groenier, W.S.; Meacham, S.A.; Stradley, J.G.

    1987-06-01

    All research and development (R and D) on civilian power reactor oxide fuel reprocessing in the United States is managed under the Consolidated Fuel Reprocessing Program (CFRP) centered at Oak Ridge National Laboratory (ORNL). A prime focus of present work is on technical exchanges and collaboration with other countries. In this context, the US Department of Energy (DOE) is in the process of negotiating a major collaboration with Japan. Both work associated with the foreign exchanges and collaboration and some on-going work are reported in overview fashion in this series of quarterly progress reports.

  17. Obtaining lower bounds from the progressive hedging algorithm for stochastic mixed-integer programs

    DOE PAGES

    Gade, Dinakar; Hackebeil, Gabriel; Ryan, Sarah M.; ...

    2016-04-02

    We present a method for computing lower bounds in the progressive hedging algorithm (PHA) for two-stage and multi-stage stochastic mixed-integer programs. Computing lower bounds in the PHA allows one to assess the quality of the solutions generated by the algorithm contemporaneously. The lower bounds can be computed in any iteration of the algorithm by using dual prices that are calculated during execution of the standard PHA. In conclusion, we report computational results on stochastic unit commitment and stochastic server location problem instances, and explore the relationship between key PHA parameters and the quality of the resulting lower bounds.

  18. Waste Tank Organic Safety Program: Analytical methods development. Progress report, FY 1994

    SciTech Connect

    Campbell, J.A.; Clauss, S.A.; Grant, K.E.

    1994-09-01

    The objectives of this task are to develop and document extraction and analysis methods for organics in waste tanks, and to extend these methods to the analysis of actual core samples to support the Waste Tank organic Safety Program. This report documents progress at Pacific Northwest Laboratory (a) during FY 1994 on methods development, the analysis of waste from Tank 241-C-103 (Tank C-103) and T-111, and the transfer of documented, developed analytical methods to personnel in the Analytical Chemistry Laboratory (ACL) and 222-S laboratory. This report is intended as an annual report, not a completed work.

  19. Fusion programs in applied plasma physics. Technical progress report, July 11, 1992--May 31, 1993

    SciTech Connect

    Not Available

    1993-07-01

    This report summarizes the progress made in theoretical and experimental research funded by US Department of Energy Grant No. DE-FG03-92ER54150, during the period July 11, 1992 through May 31, 1993. Four main tasks are reported: applied plasma physics theory, alpha particle diagnostic, edge and current density diagnostic, and plasma rotation drive. The report also discusses the research plans for the theory and experimental programs for the next grant year. Reports and publications supported by the grant during this period are listed in the final section.

  20. Fuel Performance Improvement Program. Semiannual progress report, October 1979-March 1980. [PWR; BWR

    SciTech Connect

    Not Available

    1980-04-01

    Progress on the Fuel Performance Improvement Program's fuel design tests and demonstration irradiations for October 1979 through March 1980 is reported. Included are the results of out-of-reactor experiments with Zircaloy cladding using a device that simulates the interaction between fuel and cladding. Also included are reports on the irradiation of the advanced LWR fuel designs in the Halden Boiling Water Reactor and in Consumers Power Company's Big Rock Point Reactor. The establishment of the technical bases and licensing requirements for the advanced fuel concepts are also described.