75 FR 22562 - Privacy Act of 1974; Systems of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-29

... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2010-OS-0057] Privacy Act of 1974... Federal Register Liaison Officer, Department of Defense. S335.01 System name: Training and Employee... training funded or sponsored by the Defense Logistics Agency (DLA) to include DLA employees, Department of...

D-lactic acid production by Sporolactobacillus inulinus Y2-8 immobilized in fibrous bed bioreactor using corn flour hydrolyzate.

PubMed

Zhao, Ting; Liu, Dong; Ren, Hengfei; Shi, Xinchi; Zhao, Nan; Chen, Yong; Ying, Hanjie

2014-12-28

In this study, a fibrous bed bioreactor (FBB) was used for D-lactic acid (D-LA) production by Sporolactobacillus inulinus Y2-8. Corn flour hydrolyzed with α-amylase and saccharifying enzyme was used as a cost-efficient and nutrient-rich substrate for D-LA production. A maximal starch conversion rate of 93.78% was obtained. The optimum pH for D-LA production was determined to be 6.5. Ammonia water was determined to be an ideal neutralizing agent, which improved the D-LA production and purification processes. Batch fermentation and fedbatch fermentation, with both free cells and immobilized cells, were compared to highlight the advantages of FBB fermentation. In batch mode, the D-LA production rate of FBB fermentation was 1.62 g/l/h, which was 37.29% higher than that of free-cell fermentation, and the D-LA optical purities of the two fermentation methods were above 99.00%. In fed-batch mode, the maximum D-LA concentration attained by FBB fermentation was 218.8 g/l, which was 37.67% higher than that of free-cell fermentation. Repeated-batch fermentation was performed to determine the long-term performance of the FBB system, and the data indicated that the average D-LA production rate was 1.62 g/l/h and the average yield was 0.98 g/g. Thus, hydrolyzed corn flour fermented by S. inulinus Y2-8 in a FBB may be used for improving D-LA fermentation by using ammonia water as the neutralizing agent.

32 CFR Appendix H to Part 323 - DLA Exemption Rules

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM Pt. 323, App. H Appendix H to Part 323—DLA Exemption... systems of records maintained by the Defense Logistics Agency will be exempt from the requirements of 5 U... Defense Logistics Agency claims the same exemptions for the records from those “other” systems that are...

The SDSS-DR12 large-scale cross-correlation of damped Lyman alpha systems with the Lyman alpha forest

NASA Astrophysics Data System (ADS)

Pérez-Ràfols, Ignasi; Font-Ribera, Andreu; Miralda-Escudé, Jordi; Blomqvist, Michael; Bird, Simeon; Busca, Nicolás; du Mas des Bourboux, Hélion; Mas-Ribas, Lluís; Noterdaeme, Pasquier; Petitjean, Patrick; Rich, James; Schneider, Donald P.

2018-01-01

We present a measurement of the damped Ly α absorber (DLA) mean bias from the cross-correlation of DLAs and the Ly α forest, updating earlier results of Font-Ribera et al. (2012) with the final Baryon Oscillations Spectroscopic Survey data release and an improved method to address continuum fitting corrections. Our cross-correlation is well fitted by linear theory with the standard ΛCDM model, with a DLA bias of bDLA = 1.99 ± 0.11; a more conservative analysis, which removes DLA in the Ly β forest and uses only the cross-correlation at r > 10 h-1 Mpc, yields bDLA = 2.00 ± 0.19. This assumes the cosmological model from Planck Collaboration (2016) and the Ly α forest bias factors of Bautista et al. (2017) and includes only statistical errors obtained from bootstrap analysis. The main systematic errors arise from possible impurities and selection effects in the DLA catalogue and from uncertainties in the determination of the Ly α forest bias factors and a correction for effects of high column density absorbers. We find no dependence of the DLA bias on column density or redshift. The measured bias value corresponds to a host halo mass ∼4 × 1011 h-1 M⊙ if all DLAs were hosted in haloes of a similar mass. In a realistic model where host haloes over a broad mass range have a DLA cross-section Σ (M_h) ∝ M_h^{α } down to Mh > Mmin = 108.5 h-1 M⊙, we find that α > 1 is required to have bDLA > 1.7, implying a steeper relation or higher value of Mmin than is generally predicted in numerical simulations of galaxy formation.

DoD Depot-Level Reparable Supply Chain Management: Process Effectiveness and Opportunities for Improvement

DTIC Science & Technology

2014-01-01

Memorandum QBO quantity by owner RAPS Rotables Allocation and Planning System RBOM repair bill of materials RC Recoverability Code RI Rock Island RMC...Service-owned inventory on hand in DLA distribution centers was determined using the DLA Quantity by Owner ( QBO ) file, which records the amount of...on analysis of DLA QBO file data). 4 DoD Depot-Level Reparable Supply Chain Management Budget (OMB) guidance is also very low4 and some argue

Department of Defense In-Transit Visibility Modifications

DTIC Science & Technology

2013-05-23

theorists from medieval through modern times emphasize the magnitude of a responsive logistical system. Sun Bin was a military philosopher during the...Logistics Agency (DLA) provides armed services with food, clothing , textiles, medicines, medical equipment, and construction supplies. DLA performs an

32 CFR 1290.2 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...

32 CFR 1290.2 - Purpose and scope.

Code of Federal Regulations, 2013 CFR

2013-07-01

... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...

32 CFR 1290.2 - Purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-07-01

... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...

32 CFR 1290.2 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-07-01

... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...

32 CFR 1290.2 - Purpose and scope.

Code of Federal Regulations, 2014 CFR

2014-07-01

... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...

LOGMARS (Logistics Applications of Automated Marking and Reading Symbols) Clearinghouse. Applications Directory.

DTIC Science & Technology

1985-09-01

iD- A1t62 3 ? LOOM S (LOGISTICS APPLIC TIONS OF UTO NTED M ARING 1/2 WARND READING SYMBOLS) C EARINGHOUSE APPLICATIONS DIRECTORY(U) DEFENSE GENERAL...Rubin Patterson, SC, USN, DLA DMECSO, (AV) 695-4787. 1 Encl T. R. WILD Captain, SC, U. S . Navy Chief, DLA Depot Mechanization Support Office cc; . DLA-OW...DIc.-TRIBUTrION: DLA-L DLA-Z DLA-ZS DLA- S DLA-WS DGSC-T * DPSC-C DCSC-T DFSC-W DESC-L - DESC-Q * DISC-LO * DDOU-T DDt4P--T - - DDTC-T DDMT-T DRMS DSAC

76 FR 72691 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-25

... into the DLA accounting and financial management process. Records are used by the DOD Components who...: Financial Compliance and Process Management (J-89), Headquarters, Defense Logistics Agency, 8725 John J... DoD Components who receive accounting and financial management support from DLA under an...

75 FR 48655 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-11

... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2010-OS-0112] Privacy Act of 1974... (DLA) to include DLA employees, Department of Defense military personnel, non-appropriated fund..., individual training plans, progress reports, and similar records used in intern, upward mobility, career...

A new, precise measurement of the primordial abundance of deuterium

NASA Astrophysics Data System (ADS)

Pettini, Max; Cooke, Ryan

2012-10-01

The metal-poor (Z ≃ 1/100 Z⊙) damped Lyman α system (DLA) at redshift zabs = 3.049 84 in the zem ≃ 3.030 QSO SDSS J1419+0829 has near-ideal properties for an accurate determination of the primordial abundance of deuterium (D/H)p. We have analysed a high-quality spectrum of this object with software specifically designed to deduce the best-fitting value of D/H and to assess comprehensively the random and systematic errors affecting this determination. We find (D/H)DLA = (2.535 ± 0.05) × 10-5, which in turn implies Ωb, 0h2 = 0.0223 ± 0.0009, in very good agreement with Ωb, 0h2(CMB) = 0.0222 ± 0.0004 deduced from the angular power spectrum of the cosmic microwave background (CMB). If the value in this DLA is indeed the true (D/H)p produced by big bang nucleosynthesis (BBN), there may be no need to invoke non-standard physics nor early astration of D to bring together Ωb, 0 h2(BBN) and Ωb, 0 h2(CMB). The scatter between most of the reported values of (D/H)p in the literature may be due largely to unaccounted systematic errors and biases. Further progress in this area will require a homogeneous set of data comparable to those reported here and analysed in a self-consistent manner. Such an endeavour, while observationally demanding, has the potential of improving our understanding of BBN physics, including the relevant nuclear reactions, and the subsequent processing of light nuclides through stars. Based on observations collected at the European Organisation for Astronomical Research in the Southern hemisphere, Chile [Very Large Telescope programme ID 085.A-0109(A)].

ALMA observations of a metal-rich damped Lyα absorber at z = 2.5832: evidence for strong galactic winds in a galaxy group

NASA Astrophysics Data System (ADS)

Fynbo, J. P. U.; Heintz, K. E.; Neeleman, M.; Christensen, L.; Dessauges-Zavadsky, M.; Kanekar, N.; Møller, P.; Prochaska, J. X.; Rhodin, N. H. P.; Zwaan, M.

2018-06-01

We report on the results of a search for CO(3-2) emission from the galaxy counterpart of a high-metallicity Damped Lyα Absrober (DLA) at z = 2.5832 towards the quasar Q0918+1636. We do not detect CO emission from the previously identified DLA galaxy counterpart. The limit we infer on Mgas/M⋆ is in the low end of the range found for DLA galaxies, but is still consistent with what is found for other star-forming galaxies at similar redshifts. Instead we detect CO(3-2) emission from another intensely star-forming galaxy at an impact parameter of 117 kpc from the line-of-sight to the quasar and 131 km s-1 redshifted relative to the velocity centroid of the DLA in the quasar spectrum. In the velocity profile of the low- and high-ionisation absorption lines of the DLA there is an absorption component consistent with the redshift of this CO-emitting galaxy. It is plausible that this component is physically associated with a strong outflow in the plane of the sky from the CO-emitting galaxy. If true, this would be further evidence, in addition to what is already known from studies of Lyman-break galaxies, that galactic outflows can be traced beyond 100 kpc from star-forming galaxies. The case of this z = 2.583 structure is an illustration of this in a group environment.

Metabolic engineering of Schizosaccharomyces pombe via CRISPR-Cas9 genome editing for lactic acid production from glucose and cellobiose.

PubMed

Ozaki, Aiko; Konishi, Rie; Otomo, Chisako; Kishida, Mayumi; Takayama, Seiya; Matsumoto, Takuya; Tanaka, Tsutomu; Kondo, Akihiko

2017-12-01

Modification of the Schizosaccharomyces pombe genome is often laborious, time consuming due to the lower efficiency of homologous recombination. Here, we constructed metabolically engineered S. pombe strains using a CRISPR-Cas9 system and also demonstrated D-lactic acid (D-LA) production from glucose and cellobiose. Genes encoding two separate pyruvate decarboxylases (PDCs), an L-lactic acid dehydrogenase (L-LDH), and a minor alcohol dehydrogenase (SPBC337.11) were disrupted, thereby attenuating ethanol production. To increase the cellular supply of acetyl-CoA, an important metabolite for growth, we introduced genes encoding bacterial acetylating acetaldehyde dehydrogenase enzymes (Escherichia coli MhpF and EutE). D-LA production by the resulting strain was achieved by expressing a Lactobacillus plantarum gene encoding D-lactate dehydrogenase. The engineered strain efficiently consumed glucose and produced D-LA at 25.2 g/L from 35.5 g/L of consumed glucose with a yield of 0.71 g D-LA / g glucose. We further modified this strain by expressing beta-glucosidase by cell surface display; the resulting strain produced D-LA at 24.4 g/L from 30 g/L of cellobiose in minimal medium, with a yield of 0.68 g D-LA / g glucose. To our knowledge, this study represents the first report of a S. pombe strain that was metabolically engineered using a CRISPR-Cas9 system, and demonstrates the possibility of engineering S. pombe for the production of value-added chemicals.

Eclipsing damped Ly α systems in the Sloan Digital Sky Survey Data Release 12

NASA Astrophysics Data System (ADS)

Fathivavsari, H.; Petitjean, P.; Jamialahmadi, N.; Khosroshahi, H. G.; Rahmani, H.; Finley, H.; Noterdaeme, P.; Pâris, I.; Srianand, R.

2018-07-01

We present the results of our automatic search for proximate damped Ly α absorption (PDLA) systems in the quasar spectra from the Sloan Digital Sky Survey Data Release 12. We constrain our search to those PDLAs lying within 1500 km s-1 from the quasar to make sure that the broad DLA absorption trough masks most of the strong Ly α emission from the broad-line region (BLR) of the quasar. When the Ly α emission from the BLR is blocked by these so-called eclipsing DLAs, narrow Ly α emission from the host galaxy could be revealed as a narrow emission line (NEL) in the DLA trough. We define a statistical sample of 399 eclipsing DLAs with log N(H I) ≥ 21.10. We divide our statistical sample into three subsamples based on the strength of the NEL detected in the DLA trough. By studying the stacked spectra of these subsamples, we found that absorptions from high ionization species are stronger in DLAs with stronger NEL in their absorption core. Moreover, absorption from the excited states of species like SIII are also stronger in DLAs with stronger NEL. We also found no correlation between the luminosity of the Ly α NEL and the quasar luminosity. These observations are consistent with a scenario in which the DLAs with stronger NEL are denser and physically closer to the quasar. We propose that these eclipsing DLAs could be the product of the interaction between infalling and outflowing gas. High-resolution spectroscopic observation would be needed to shed some light on the nature of these eclipsing DLAs.

Financial Improvement and Audit Readiness (FIAR) Plan Status Report

DTIC Science & Technology

2011-05-01

integrated personnel and pay system that will consolidate Guard, Reserve, and Active Duty Military into a single system for personnel and pay...Inventory The DLA is the integrated material manager for assigned federal supply classes. The DLA holds materiel based on military and...Monitoring DoD Component progress and holding them accountable is essential to success and to achieving the Department’s commitment to audit readiness by

Spatially Resolved Emission of a z~3 Damped Lyman Alpha Galaxy with Keck/OSIRIS IFU

NASA Astrophysics Data System (ADS)

Christenson, Holly; Jorgenson, Regina

2017-01-01

The damped Lyman alpha (DLA) class of galaxies contains most of the neutral hydrogen gas over cosmic time. Few DLAs have been detected directly, which limits our knowledge of fundamental properties like size and mass. We present Keck/OSIRIS infrared integral field spectroscopy (IFU) observations of a DLA that was first detected in absorption toward a background quasar. Our observations use the Keck Laser Guide Star Adaptive Optics system to reduce the point-spread function of the quasar, making it possible to spatially resolve the DLA emission. We map this emission in O[III] 5007 Å. At redshift z~3, this DLA represents one of the highest redshift DLAs mapped with IFU spectroscopy. We present measurements of the star formation rate, metallicity, and gas mass of the galaxy.This project was supported in part by the NSF REU grant AST-1358980 and by the Nantucket Maria Mitchell Association.

Eclipsing damped Lyα systems in the Sloan Digital Sky Survey Data Release 12★

NASA Astrophysics Data System (ADS)

Fathivavsari, H.; Petitjean, P.; Jamialahmadi, N.; Khosroshahi, H. G.; Rahmani, H.; Finley, H.; Noterdaeme, P.; Pâris, I.; Srianand, R.

2018-04-01

We present the results of our automatic search for proximate damped Lyα absorption (PDLA) systems in the quasar spectra from the Sloan Digital Sky Survey Data Release 12. We constrain our search to those PDLAs lying within 1500 km s-1 from the quasar to make sure that the broad DLA absorption trough masks most of the strong Lyα emission from the broad line region (BLR) of the quasar. When the Lyα emission from the BLR is blocked by these so-called eclipsing DLAs, narrow Lyα emission from the host galaxy could be revealed as a narrow emission line (NEL) in the DLA trough. We define a statistical sample of 399 eclipsing DLAs with log N(H I) ≥ 21.10. We divide our statistical sample into three subsamples based on the strength of the NEL detected in the DLA trough. By studying the stacked spectra of these subsamples, we found that absorption from high ionization species are stronger in DLAs with stronger NEL in their absorption core. Moreover, absorption from the excited states of species like Si II are also stronger in DLAs with stronger NEL. We also found no correlation between the luminosity of the Lyα NEL and the quasar luminosity. These observations are consistent with a scenario in which the DLAs with stronger NEL are denser and physically closer to the quasar. We propose that these eclipsing DLAs could be the product of the interaction between infalling and outflowing gas. High resolution spectroscopic observation would be needed to shed some light on the nature of these eclipsing DLAs.

77 FR 39487 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-03

... in any law enforcement or security matter on DLA property, which requires DLA Police response or... matter on DLA property, which requires DLA Police response or contact. Law Enforcement matters include... property, incident reports, blotters, qualifications, dispatching, and other police information management...

76 FR 38117 - Notice of Intent To Prepare an Environmental Assessment Regarding DLA Energy's Mobility Fuel...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-29

... Prepare an Environmental Assessment Regarding DLA Energy's Mobility Fuel Purchasing Programs AGENCY... Assessment Regarding DLA Energy's Mobility Fuel Purchasing Programs. SUMMARY: The Defense Logistics Agency is... deployment of fuels and other energy sources. DLA Energy's action, to purchase mobility fuels for the...

Documentation Library Application (DLA) Version 2.0.0.1, User Guide

DTIC Science & Technology

2013-05-08

document DIScard chotnoes and undo <ht:dc-oot. View AN Library ~IR8librMY ~ooc~~.tiOn Llbt~ry View W AA Library View ~MI Libr -ary...Windows XP and access to the DLA SQL Server database. To install the DLA, navigate to N:\\Dept 161\\3 - PRODUCTS\\ Software Installation...Health Research Center. You should see the DLA menu item listed under the NHRC programs there. Contact the DLA software POC if you encounter any

75 FR 43944 - Membership of the Defense Logistics Agency (DLA) Senior Executive Service (SES) Performance...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-27

... CONTACT: Ms. Lisa Novajosky, SES Program Manager, DLA Human Resources (J-14), Defense Logistics Agency..., Director, DLA Finance. Members: Mr. Brad Bunn, Director, DLA Human Resources (Non-Voting Member); Ms. Mae... management of the SES cadre. DATES: Effective Date: September 16, 2010. ADDRESSES: Defense Logistics Agency...

DLA-DRB1, DQA1, and DQB1 alleles and haplotypes in North American Gray Wolves.

PubMed

Kennedy, Lorna J; Angles, John M; Barnes, Annette; Carmichael, Lindsey E; Radford, Alan D; Ollier, William E R; Happ, George M

2007-01-01

The canine major histocompatibility complex contains highly polymorphic genes, many of which are critical in regulating immune response. Since domestic dogs evolved from Gray Wolves (Canis lupus), common DLA class II alleles should exist. Sequencing was used to characterize 175 Gray Wolves for DLA class II alleles, and data from 1856 dogs, covering 85 different breeds of mostly European origin, were available for comparison. Within wolves, 28 new alleles were identified, all occurring in at least 2 individuals. Three DLA-DRB1, 8 DLA-DQA1, and 6 DLA-DQB1 alleles also identified in dogs were present. Twenty-eight haplotypes were identified, of which 2 three-locus haplotypes, and many DLA-DQA1/DQB1 haplotypes, are also found in dogs. The wolves studied had relatively few dog DLA alleles and may therefore represent a remnant population descended from Asian wolves. The single European wolf included carried a haplotype found in both these North American wolves and in many dog breeds. Furthermore, one wolf DQB1 allele has been found in Shih Tzu, a breed of Asian origin. These data suggest that the wolf ancestors of Asian and European dogs may have had different gene pools, currently reflected in the DLA alleles present in dog breeds.

A Candidate for an Intrinsic Dusty Absorber with a Metal-rich Damped Lyα Absorption Line System in the Quasar J170542.91+354340.2

NASA Astrophysics Data System (ADS)

Pan, Xiang; Zhou, Hongyan; Ge, Jian; Jiang, Peng; Yang, Bin; Lu, Honglin; Ji, Tuo; Zhang, Shaohua; Shi, Xiheng

2017-02-01

We present a detailed analysis of the unusual damped Lyα absorption line system (DLA) toward the quasar SDSS J170542.91+354340.2 at a redshift of 2, previously reported by Noterdaeme et al. as one of the very few CO absorbers known to date at high z. This DLA is exceptional in that: (1) its extinction curve is similar to peculiar Milky Way sightlines penetrating star formation regions; (2) its absorption components are redshifted at a speed of several hundred km s-1 compared to broad Balmer emission lines; (3) its gas-phase metallicity is super-solar as evaluated from more than 30 absorption lines; (4) detection of residual flux in the DLA trough and variability of {{C}} {{IV}} absorption is possible. Based on these facts, we argue that this dusty DLA is a good candidate for an intrinsic quasar 2175 Å absorber, and can originate from star formation regions of the quasar’s host galaxy. We discuss in detail the gas and dust properties, and the dust depletion. Follow-up observations, such as spectropolarimetry and optical/infrared spectroscopy, will help to confirm the system’s intrinsic nature and to explore how dust grains behave in the extreme environments proximate to quasars.

Dollar Summary of Federal Supply Classification and Service Category by Company, FY83, Part 3 (7025-9999).

DTIC Science & Technology

1983-01-01

NEW YORK ARMY KITCHEN HAND TOOLS AND UTENSILS 45 FSC TOTAL 235 7340 GEORGIA FACTORY FOR THE BLIND GEORGIA DLA CUTLERY AND FLATWARE 743 NATIONAL...INDUSTRIES FOR THE BLIND NEW JERSEY DLA CUTLERY AND FLATWARE 97 REEM 4 BARTON CORP MASS NAVY CUTLERY AND FLATWARE 52 FSC TOTAL- 892 DEPARTMENT OF DEFENSE...69,060 8945 ANDERSON CLAYTON & CO ILLINOIS DLA FOOD OILS AND FATS 387 TEXAS DLA FOOD OILS AND FATS 27 CONTRACTOR TOTAL 414 BUNGE EDIBLE OIL TENNESSEE DLA

Modeling fractal cities using the correlated percolation model.

NASA Astrophysics Data System (ADS)

Makse, Hernán A.; Havlin, Shlomo; Stanley, H. Eugene

1996-03-01

Cities grow in a way that might be expected to resemble the growth of two-dimensional aggregates of particles, and this has led to recent attempts to model urban growth using ideas from the statistical physics of clusters. In particular, the model of diffusion limited aggregation (DLA) has been invoked to rationalize the apparently fractal nature of urban morphologies(M. Batty and P. Longley, Fractal Cities) (Academic, San Diego, 1994). The DLA model predicts that there should exist only one large fractal cluster, which is almost perfectly screened from incoming 'development units' (representing, for example, people, capital or resources), so that almost all of the cluster growth takes place at the tips of the cluster's branches. We show that an alternative model(H. A. Makse, S. Havlin, H. E. Stanley, Nature 377), 608 (1995), in which development units are correlated rather than being added to the cluster at random, is better able to reproduce the observed morphology of cities and the area distribution of sub-clusters ('towns') in an urban system, and can also describe urban growth dynamics. Our physical model, which corresponds to the correlated percolation model in the presence of a density gradient, is motivated by the fact that in urban areas development attracts further development. The model offers the possibility of predicting the global properties (such as scaling behavior) of urban morphologies.

Discovery of a Damped Lyα Absorber at z = 3.3 along a Galaxy Sight-line in the SSA22 Field

NASA Astrophysics Data System (ADS)

Mawatari, K.; Inoue, A. K.; Kousai, K.; Hayashino, T.; Cooke, R.; Prochaska, J. X.; Yamada, T.; Matsuda, Y.

2016-02-01

Using galaxies as background light sources to map the Lyα absorption lines is a novel approach to study Damped Lyα Absorbers (DLAs). We report the discovery of an intervening z = 3.335 ± 0.007 DLA along a galaxy sight-line identified among 80 Lyman Break Galaxy (LBG) spectra obtained with our Very Large Telescope/Visible Multi-Object Spectrograph survey in the SSA22 field. The measured DLA neutral hydrogen (H I) column density is log(NH I/cm-2) = 21.68 ± 0.17. The DLA covering fraction over the extended background LBG is >70% (2σ), yielding a conservative constraint on the DLA area of ≳1 kpc2. Our search for a counterpart galaxy hosting this DLA concludes that there is no counterpart galaxy with star formation rate larger than a few M⊙ yr-1, ruling out an unobscured violent star formation in the DLA gas cloud. We also rule out the possibility that the host galaxy of the DLA is a passive galaxy with M* ≳ 5 × 1010M⊙ or a heavily dust-obscured galaxy with E(B - V) ≳ 2. The DLA may coincide with a large-scale overdensity of the spectroscopic LBGs. The occurrence rate of the DLA is compatible with that of DLAs found in QSO sight-lines.

HISTOCOMPATIBILITY STUDIES IN A CLOSELY BRED COLONY OF DOGS

PubMed Central

Rapaport, Felix T.; Boyd, Arthur D.; Spencer, Frank C.; Lower, Richard R.; Dausset, Jean; Cannon, Florence D.; Ferrebee, Joseph W.

1971-01-01

The DL-A system of histocompatibility plays an important role in conditioning the survival of cardiac allografts in the unmodified canine host. The mean survival time of six cardiac allografts performed in DL-A-compatible littermate dogs obtained from a closely bred colony of beagles was 53.2 days, while the MST of transplants performed in seven DL-A-incompatible animals was 7.3 days. The MST of cardiac allografts performed in nine DL-A-compatible nonlittermate beagles was 26.3 days, as compared with 6.3 days in six DL-A-incompatible nonlittermate transplants. The results did not appear to be affected by Swisher erythrocyte-group incompatibilities. The MST of 28 cardiac allografts performed in randomly selected mongrel dogs was 10.0 days. Incompatibilities for DL-A antigens e, f, g, l, and m may constitute major barriers to transplantation, but antigens b, c, d, and k appeared to act as weak histocompatibility antigens. Under controlled conditions of donor-recipient DL-A compatibility, cardiac allografts may be less immunogenic than renal transplants. Heart transplants performed across major donor-recipient DL-A incompatibilities appeared, however, to be more vulnerable to the events of allograft rejection than renal allografts performed under similar conditions. The selection of optimally compatible donor-recipient combinations for organ transplantation may be aided materially by genetic studies of the transmission of DL-A antigens to the animals under consideration. PMID:4943931

Quantitative DLA-based compressed sensing for T1-weighted acquisitions

NASA Astrophysics Data System (ADS)

Svehla, Pavel; Nguyen, Khieu-Van; Li, Jing-Rebecca; Ciobanu, Luisa

2017-08-01

High resolution Manganese Enhanced Magnetic Resonance Imaging (MEMRI), which uses manganese as a T1 contrast agent, has great potential for functional imaging of live neuronal tissue at single neuron scale. However, reaching high resolutions often requires long acquisition times which can lead to reduced image quality due to sample deterioration and hardware instability. Compressed Sensing (CS) techniques offer the opportunity to significantly reduce the imaging time. The purpose of this work is to test the feasibility of CS acquisitions based on Diffusion Limited Aggregation (DLA) sampling patterns for high resolution quantitative T1-weighted imaging. Fully encoded and DLA-CS T1-weighted images of Aplysia californica neural tissue were acquired on a 17.2T MRI system. The MR signal corresponding to single, identified neurons was quantified for both versions of the T1 weighted images. For a 50% undersampling, DLA-CS can accurately quantify signal intensities in T1-weighted acquisitions leading to only 1.37% differences when compared to the fully encoded data, with minimal impact on image spatial resolution. In addition, we compared the conventional polynomial undersampling scheme with the DLA and showed that, for the data at hand, the latter performs better. Depending on the image signal to noise ratio, higher undersampling ratios can be used to further reduce the acquisition time in MEMRI based functional studies of living tissues.

A Glimpse at Quasar Host Galaxy Far-UV Emission, Using Damped Lyα's as Natural Coronagraphs

DOE PAGES

Cai, Zheng; Fan, Xiaohui; Noterdaeme, Pasquier; ...

2014-09-16

In merger-driven models of massive galaxy evolution, the luminous quasar phase is expected to be accompanied by vigorous star formation in quasar host galaxies. In this paper, we use high column density damped Lyα (DLA) systems along quasar sight lines as natural coronagraphs to directly study the far-UV (FUV) radiation from the host galaxies of luminous background quasars. Here, we have stacked the spectra of ~2000 DLA systems (N HI > 10 20.6cm –2) with a median absorption redshiftmore » $$\\langle$$z$$\\rangle$$ = 2.6 selected from quasars observed in the SDSS-III Baryon Oscillation Spectroscopic Survey. We detect residual flux in the dark troughs of the composite DLA spectra. The level of this residual flux significantly exceeds systematic errors in the Sloan Digital Sky Survey fiber sky subtraction; furthermore, the residual flux is strongly correlated with the continuum luminosity of the background quasar, while uncorrelated with DLA column density or metallicity. We conclude that the flux could be associated with the average FUV radiation from the background quasar host galaxies (with medium redshift $$\\langle$$z$$\\rangle$$ = 3.1) that is not blocked by the intervening DLA. Finally, assuming that all of the detected flux originates from quasar hosts, for the highest quasar luminosity bin ($$\\langle$$L$$\\rangle$$ = 2.5 × 10 13 L ⊙), the host galaxy has an FUV intensity of 1.5 ± 0.2 × 10 40 erg s –1 Å –1; this corresponds to an unobscured UV star formation rate of 9 M ⊙ yr –1.« less

A glimpse at quasar host galaxy far-UV emission using damped Lyα's as natural coronagraphs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cai, Zheng; Fan, Xiaohui; Wang, Ran

2014-10-01

In merger-driven models of massive galaxy evolution, the luminous quasar phase is expected to be accompanied by vigorous star formation in quasar host galaxies. In this paper, we use high column density damped Lyα (DLA) systems along quasar sight lines as natural coronagraphs to directly study the far-UV (FUV) radiation from the host galaxies of luminous background quasars. We have stacked the spectra of ∼2000 DLA systems (N {sub H} {sub I} > 10{sup 20.6} cm{sup –2}) with a median absorption redshift (z) = 2.6 selected from quasars observed in the SDSS-III Baryon Oscillation Spectroscopic Survey. We detect residual fluxmore » in the dark troughs of the composite DLA spectra. The level of this residual flux significantly exceeds systematic errors in the Sloan Digital Sky Survey fiber sky subtraction; furthermore, the residual flux is strongly correlated with the continuum luminosity of the background quasar, while uncorrelated with DLA column density or metallicity. We conclude that the flux could be associated with the average FUV radiation from the background quasar host galaxies (with medium redshift (z) = 3.1) that is not blocked by the intervening DLA. Assuming that all of the detected flux originates from quasar hosts, for the highest quasar luminosity bin ((L) = 2.5 × 10{sup 13} L {sub ☉}), the host galaxy has an FUV intensity of 1.5 ± 0.2 × 10{sup 40} erg s{sup –1} Å{sup –1}; this corresponds to an unobscured UV star formation rate of 9 M {sub ☉} yr{sup –1}.« less

H I OBSERVATIONS OF THE Ca II ABSORBING GALAXIES Mrk 1456 AND SDSS J211701.26-002633.7

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cherinka, B.; Schulte-Ladbeck, R. E.; Rosenberg, J. L.

2009-12-15

In an effort to study Damped Ly{alpha} (DLA) galaxies at low redshift, we have been using the Sloan Digital Sky Survey (SDSS) to identify galaxies projected onto quasi-stellar object (QSO) sight lines and to characterize their optical properties. For low-redshift galaxies, the H I 21 cm emission line can be used as an alternate tool for identifying possible DLA galaxies, since H I-emitting galaxies typically exhibit H I columns that are larger than the classical DLA limit. Here, we report on follow-up H I 21 cm emission-line observations of two DLA candidates that are both low-redshift spiral galaxies, Mrk 1456more » and SDSS J211701.26-002633.7. The observations were made using the Green Bank Telescope (GBT) and Arecibo telescope, respectively. Analysis of their H I properties reveal the galaxies to be about one and two M*{sub HI} galaxies, respectively, and to have average H I mass, gas richness, and gas-mass fraction for their morphological types. We consider Mrk 1456 and SDSS J211701.26-002633.7 to be candidate DLA systems based upon the strength of the Ca II absorption lines they cause in their QSO's spectra, and impact parameters to the QSO that are smaller than the stellar disk. Compared to the small numbers of other H I detected DLA and candidate DLA galaxies, Mrk 1456 and SDSS J211701.26-002633.7 have high H I masses. Mrk 1456 and SDSS J211701.26-002633.7 have also been found to lie in galaxy groups that are high in H I gas mass compared to the group containing SBS 1543+593, the only DLA galaxy previously known to be situated in a galaxy group. When compared with the expected properties of low-z DLAs from an H I-detected sample of galaxies, Mrk 1456 and SDSS J211701.26-002633.7 fall within the ranges for impact parameter and M{sub B} ; and the H I mass distribution for the H I-detected DLAs agrees with that of the expected H I mass distribution for low-z DLAs. Our observations support galaxy-evolution models in which high-mass galaxies make up an increasing contribution to the DLA cross section at lower redshifts. We also report on the 21 cm line emission of Mrk 1457, a Seyfert galaxy observed within the beam of the GBT.« less

32 CFR 1290.7 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Responsibilities. (a) HQ DLA. (1) The Command Security Officer, DLA (DLA-T) will: (i) Exercise staff supervision... enforcement/security force (080, 083, 085 and 1800 series) personnel to issue DD Form 1805. (3) Periodically...

32 CFR 1290.7 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Responsibilities. (a) HQ DLA. (1) The Command Security Officer, DLA (DLA-T) will: (i) Exercise staff supervision... enforcement/security force (080, 083, 085 and 1800 series) personnel to issue DD Form 1805. (3) Periodically...

76 FR 22681 - Defense Logistics Agency (DLA) Address Directory

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-22

... FOIA/Privacy Points of Contact are found at: http://www.dla.mil/foia-privacy/foia_poc.aspx . FOR FURTHER INFORMATION CONTACT: Ms. Jody Sinkler, 703-767-5045. SUPPLEMENTARY INFORMATION: DLA Address...

Restricted dog leucocyte antigen (DLA) class II haplotypes and genotypes in Beagles.

PubMed

Soutter, Francesca; Kennedy, Lorna J; Ollier, William E R; Solano-Gallego, Laia; Catchpole, Brian

2015-03-01

Beagles are commonly used in vaccine trials as part of the regulatory approval process. Genetic restriction within this breed and the impact this might have on vaccine responses are rarely considered. This study was designed to characterise diversity of dog leucocyte antigen (DLA) class II genes in a breeding colony of laboratory Beagles, whose offspring are used in vaccine studies. DLA haplotypes were determined by PCR and sequence-based typing from genomic DNA extracted from blood. Breeding colony Beagles had significantly different DLA haplotype frequencies in comparison with pet Beagles and both groups showed limited DLA diversity. Restricted DLA class II genetic variability within Beagles might result in selective antigen presentation and vaccine responses that are not necessarily representative of those seen in other dog breeds. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

VizieR Online Data Catalog: SDSS DLA and absorber quasar samples (Murphy+, 2016)

NASA Astrophysics Data System (ADS)

Murphy, M. T.; Bernet, M. L.

2016-07-01

Using spectral slope fits of the SDSS DR7 quasar spectra, and the DLA/sub-DLA identifications of Noterdaeme et al. (2009, Cat. J/A+A/505/1087), we found that the 774 selected quasars with a single foreground DLA are significantly (3.2σ) redder, on average, than carefully selected control groups drawn from a sample of ~7000 quasars without foreground DLAs. (4 data files).

Identification of novel genetic risk loci in Maltese dogs with necrotizing meningoencephalitis and evidence of a shared genetic risk across toy dog breeds.

PubMed

Schrauwen, Isabelle; Barber, Renee M; Schatzberg, Scott J; Siniard, Ashley L; Corneveaux, Jason J; Porter, Brian F; Vernau, Karen M; Keesler, Rebekah I; Matiasek, Kaspar; Flegel, Thomas; Miller, Andrew D; Southard, Teresa; Mariani, Christopher L; Johnson, Gayle C; Huentelman, Matthew J

2014-01-01

Necrotizing meningoencephalitis (NME) affects toy and small breed dogs causing progressive, often fatal, inflammation and necrosis in the brain. Genetic risk loci for NME previously were identified in pug dogs, particularly associated with the dog leukocyte antigen (DLA) class II complex on chromosome 12, but have not been investigated in other susceptible breeds. We sought to evaluate Maltese and Chihuahua dogs, in addition to pug dogs, to identify novel or shared genetic risk factors for NME development. Genome-wide association testing of single nucleotide polymorphisms (SNPs) in Maltese dogs with NME identified 2 regions of genome-wide significance on chromosomes 4 (chr4:74522353T>A, p = 8.1×10-7) and 15 (chr15:53338796A>G, p = 1.5×10-7). Haplotype analysis and fine-mapping suggests that ILR7 and FBXW7, respectively, both important for regulation of immune system function, could be the underlying associated genes. Further evaluation of these regions and the previously identified DLA II locus across all three breeds, revealed an enrichment of nominal significant SNPs associated with chromosome 15 in pug dogs and DLA II in Maltese and Chihuahua dogs. Meta-analysis confirmed effect sizes the same direction in all three breeds for both the chromosome 15 and DLA II loci (p = 8.6×10-11 and p = 2.5×10-7, respectively). This suggests a shared genetic background exists between all breeds and confers susceptibility to NME, but effect sizes might be different among breeds. In conclusion, we identified the first genetic risk factors for NME development in the Maltese, chromosome 4 and chromosome 15, and provide evidence for a shared genetic risk between breeds associated with chromosome 15 and DLA II. Last, DLA II and IL7R both have been implicated in human inflammatory diseases of the central nervous system such as multiple sclerosis, suggesting that similar pharmacotherapeutic targets across species should be investigated.

Additive Manufacturing: Which DLA-Managed Legacy Parts are Potential AM Candidates

DTIC Science & Technology

2016-07-01

R G ADDITIVE MANUFACTURING : WHICH DLA-MANAGED LEGACY PARTS ARE POTENTIAL AM CANDIDATES? REPORT DL501T1 J UL Y 2016...L Y 2 0 1 6 ADDITIVE MANUFACTURING : WHICH DLA-MANAGED LEGACY PARTS ARE POTENTIAL AM CANDIDATES? REPORT DL501T1 Thomas K . Pa rk s...DESIGNATED BY OTHER OFFICIAL DOCUMENTATION. LMI © 2016. ALL RIGHTS RESERVED. iii Additive Manufacturing : Which DLA-Managed Legacy Parts Are

DISCOVERY OF A DAMPED Lyα ABSORBER AT z = 3.3 ALONG A GALAXY SIGHT-LINE IN THE SSA22 FIELD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mawatari, K.; Inoue, A. K.; Kousai, K.

2016-02-01

Using galaxies as background light sources to map the Lyα absorption lines is a novel approach to study Damped Lyα Absorbers (DLAs). We report the discovery of an intervening z = 3.335 ± 0.007 DLA along a galaxy sight-line identified among 80 Lyman Break Galaxy (LBG) spectra obtained with our Very Large Telescope/Visible Multi-Object Spectrograph survey in the SSA22 field. The measured DLA neutral hydrogen (H i) column density is log(N{sub H} {sub i}/cm{sup −2}) = 21.68 ± 0.17. The DLA covering fraction over the extended background LBG is >70% (2σ), yielding a conservative constraint on the DLA area of ≳1 kpc{sup 2}. Our search for a counterpartmore » galaxy hosting this DLA concludes that there is no counterpart galaxy with star formation rate larger than a few M{sub ⊙} yr{sup −1}, ruling out an unobscured violent star formation in the DLA gas cloud. We also rule out the possibility that the host galaxy of the DLA is a passive galaxy with M{sub *} ≳ 5 × 10{sup 10}M{sub ⊙} or a heavily dust-obscured galaxy with E(B − V) ≳ 2. The DLA may coincide with a large-scale overdensity of the spectroscopic LBGs. The occurrence rate of the DLA is compatible with that of DLAs found in QSO sight-lines.« less

The astrophysical consequences of intervening galaxy gas on fast radio bursts

NASA Astrophysics Data System (ADS)

Prochaska, J. Xavier; Neeleman, Marcel

2018-02-01

We adopt and analyze results on the incidence and physical properties of damped Ly$\\alpha$ systems (DLAs) to predict the astrophysical impact of gas in galaxies on observations of Fast Radio Bursts (FRBs). Three DLA measures form the basis of this analysis: (i) the HI column density distribution, parameterized as a double power-law; (ii) the incidence of DLAs with redshift (derived here), $\\ell(z)=A+B \\arctan(z-C)$ with $A=0.236_{-0.021}^{+0.016}, B=0.168_{-0.017}^{+0.010}, C=2.87_{-0.13}^{+0.17}$ and (iii) the electron density, parameterized as a log-normal deviate with mean $10^{-2.6} cm^{-3}$ and dispersion 0.3dex. Synthesizing these results, we estimate that the average rest-frame dispersion measure from the neutral medium of a single, intersecting galaxy is DM$^{NM}_{DLA}=0.25$ pc/cm^3. Analysis of AlIII and CII* absorption limits the putative warm ionized medium to contribute DM$^{WIM}_{DLA}<20$pc/cm^3. Given the low incidence of DLAs, we find that a population of FRBs at z=2 will incur DM(z=2)=0.01 pc/cm^3 on average, with a 99% c.l. upper bound of 0.22 pc/cm^3. Assuming that turbulence of the ISM in external galaxies is qualitatively similar to our Galaxy, we estimate that the angular broadening of an FRB by intersecting galaxies is negligible ($\\theta<0.1$mas). The temporal broadening is also predicted to be small, $\\tau \\approx 0.3$ms for a z=1 galaxy intersecting a z=2 FRB for an observing frequency of $\

Improving DLA Aviation Engineering’s Support to its Customers and the DoD Supply Chain

DTIC Science & Technology

2014-10-01

costs and first article test costs) and (2) DLA supply chain responsiveness as measured in terms of the days required to satisfy unfilled orders ( UFOs ...135,000 UFOs or requisitions at any time. This number of UFOs overstates the magnitude of the backorder problem since many of these backorders are...backorders or long term unfilled orders ( UFOs ). This can have serious implications for the materiel readiness of those weapon systems that utilize

Direct Laser Acceleration in Laser Wakefield Accelerators

NASA Astrophysics Data System (ADS)

Shaw, J. L.; Froula, D. H.; Marsh, K. A.; Joshi, C.; Lemos, N.

2017-10-01

The direct laser acceleration (DLA) of electrons in a laser wakefield accelerator (LWFA) has been investigated. We show that when there is a significant overlap between the drive laser and the trapped electrons in a LWFA cavity, the accelerating electrons can gain energy from the DLA mechanism in addition to LWFA. The properties of the electron beams produced in a LWFA, where the electrons are injected by ionization injection, have been investigated using particle-in-cell (PIC) code simulations. Particle tracking was used to demonstrate the presence of DLA in LWFA. Further PIC simulations comparing LWFA with and without DLA show that the presence of DLA can lead to electron beams that have maximum energies that exceed the estimates given by the theory for the ideal blowout regime. The magnitude of the contribution of DLA to the energy gained by the electron was found to be on the order of the LWFA contribution. The presence of DLA in a LWFA can also lead to enhanced betatron oscillation amplitudes and increased divergence in the direction of the laser polarization. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele.

PubMed

Kennedy, L J; Quarmby, S; Happ, G M; Barnes, A; Ramsey, I K; Dixon, R M; Catchpole, B; Rusbridge, C; Graham, P A; Hillbertz, N S; Roethel, C; Dodds, W J; Carmichael, N G; Ollier, W E R

2006-07-01

Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown.

32 CFR 1292.4 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Responsibilities. 1292.4 Section 1292.4 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.4 Responsibilities. (a) HQ DLA. (1) The Director, DLA/Deputy...

32 CFR 1292.4 - Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Responsibilities. 1292.4 Section 1292.4 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.4 Responsibilities. (a) HQ DLA. (1) The Director, DLA/Deputy...

32 CFR 1292.4 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Responsibilities. 1292.4 Section 1292.4 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.4 Responsibilities. (a) HQ DLA. (1) The Director, DLA/Deputy...

32 CFR 1292.4 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Responsibilities. 1292.4 Section 1292.4 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.4 Responsibilities. (a) HQ DLA. (1) The Director, DLA/Deputy...

MHC class II is an important genetic risk factor for canine systemic lupus erythematosus (SLE)-related disease: implications for reproductive success.

PubMed

Wilbe, M; Andersson, G

2012-01-01

Major histocompatibility complex (MHC) class II genes are important genetic risk factors for development of immune-mediated diseases in mammals. Recently, the dog (Canis lupus familiaris) has emerged as a useful model organism to identify critical MHC class II genotypes that contribute to development of these diseases. Therefore, a study aimed to evaluate a potential genetic association between the dog leukocyte antigen (DLA) class II region and an immune-mediated disease complex in dogs of the Nova Scotia duck tolling retriever breed was performed. We show that DLA is one of several genetic risk factors for this disease complex and that homozygosity of the risk haplotype is disadvantageous. Importantly, the disease is complex and has many genetic risk factors and therefore we cannot provide recommendations for breeders exclusively on the basis of genetic testing for DLA class II genotype. © 2012 Blackwell Verlag GmbH.

Intestinal microbial and metabolic alterations following successful fecal microbiota transplant for D-lactic acidosis.

PubMed

Bulik-Sullivan, Emily C; Roy, Sayanty; Elliott, Ryan J; Kassam, Zain; Lichtman, Steven N; Carroll, Ian M; Gulati, Ajay S

2018-06-12

Fecal microbiota transplantation (FMT) involves the transfer of stool from a healthy individual into the intestinal tract of a diseased recipient. Although used primarily for recurrent Clostridium difficile infection, FMT is increasingly being attempted as an experimental therapy for other illnesses, including metabolic disorders. D-lactic acidosis (D-LA) is a metabolic disorder that may occur in individuals with short bowel syndrome when lactate-producing bacteria in the colon overproduce D-lactate. This results in elevated systemic levels of D-lactate, metabolic acidosis, and encephalopathy. In this study, we report the successful use of FMT for the treatment of recurrent D-LA in a child who was unresponsive to conventional therapies. Importantly, we also present profiles of the enteric microbiota, as well as fecal D-/L-lactic acid metabolites, before and longitudinally after FMT. These data provide valuable insight into the putative mechanisms of D-LA pathogenesis and its treatment.

Enhanced production of optically pure d (-) lactic acid from nutritionally rich Borassus flabellifer sugar and whey protein hydrolysate based-fermentation medium.

PubMed

Reddy Tadi, Subbi Rami; E V R, Arun; Limaye, Anil Mukund; Sivaprakasam, Senthilkumar

2017-03-01

The aim of this study is to optimize the production of optically pure d (-) lactic acid (DLA) employing a cost-effective production medium. Based on the designed biomass approach, Sporolactobacillus inulinus NBRC 13595 was found to exhibit high DLA titer (19.0 g L -1 ) and optical purity (99.6%). A cost-effective medium was constituted using Palmyra palm jaggery (PJ) from Borassus flabellifer and whey protein hydrolysate (WPH) as carbon and nitrogen sources, respectively. Plackett-Burman design indicated that PJ, WPH, and MnSO 4 as significant variables influence DLA production. A rotatable central composite design and response surface methodology were used to optimize the PJ and WPH concentrations. A maximum DLA titer (170.14 g L -1 ) was predicted for 222.24 g L -1 of PJ and 11.99 g L -1 of WPH, respectively. Fermentation experimental results exhibited a maximum DLA titer (189.0 ± 8.53 g L -1 ) and productivity (5.25 ± 0.24 g L -1 H -1 ), which is the highest ever reported for DLA production from a renewable feedstock in the batch process. The present investigation substantiates that the potential application of economically viable raw feedstocks (PJ and WPH) for enhanced DLA production, which is attributed to 2.5-fold reduction in DLA production cost compared with conventional medium. © 2015 International Union of Biochemistry and Molecular Biology, Inc.

Directly Imaging Damped Ly-Alpha Galaxies at Redshifts Greater Than 2. III: The Star Formation Rates of Neutral Gas Reservoirs at Redshifts of Approximately 2.7

NASA Technical Reports Server (NTRS)

Fumagalli, Michele; OMeara, John M.; Prochaska, J. Xavier; Rafelski, Marc; Kanekar, Nissim

2014-01-01

We present results from a survey designed to probe the star formation properties of 32 damped Ly alpha systems (DLAs) at redshifts of approximately 2.7. By using the "double-DLA" technique that eliminates the glare of the bright background quasars, we directly measure the rest-frame FUV flux from DLAs and their neighbouring galaxies. At the position of the absorbing gas, we place stringent constraints on the unobscured star formation rates (SFRs) of DLAs to 2 sigma limits of psi less than 0.09-0.27 solar mass yr(exp -1), corresponding to SFR surface densities sigma(sub sfr) less than 10(exp -2.6)-10(exp -1.5) solar mass yr(exp -1) kpc(exp -2). The implications of these limits for the star formation law, metal enrichment, and cooling rates of DLAs are examined. By studying the distribution of impact parameters as a function of SFRs for all the galaxies detected around these DLAs, we place new direct constraints on the bright end of the UV luminosity function of DLA hosts. We find that less than or equal to 13% of the hosts have psi greater than or equal to 2 solar mass yr(exp -1) at impact parameters b(sub dla) less than or equal to (psi/solar mass yr(exp -1))(exp 0.8) + 6 kpc, differently from current samples of confirmed DLA galaxies. Our observations also disfavor a scenario in which the majority of DLAs arise from bright LBGs at distances 20 less than or equal to b(sub dla) less than 100 kpc. These new findings corroborate a picture in which DLAs do not originate from highly star forming systems that are coincident with the absorbers, and instead suggest that DLAs are associated with faint, possibly isolated, star-forming galaxies. Potential shortcomings of this scenario and future strategies for further investigation are discussed.

The Nation's Combat Logistics Support Agency

Science.gov Websites

CENTCOM & SOCOM DLA Europe & Africa DLA Pacific History News Careers A graphic shows rows of cross -shaped gravestones in a cemetery with the words Heritage, History, Heroes over a partial American Flag background Remembering heritage, history and heroes on Memorial Day This Memorial Day, DLA employees and

Characterization of class II alpha genes and DLA-D region allelic associations in the dog.

PubMed

Sarmiento, U M; Storb, R F

1988-10-01

Human major histocompatibility complex (HLA) cDNA probes were used to analyze the restriction fragment length polymorphism (RFLP) of the alpha genes of the DLA-D region in dogs. Genomic DNA from peripheral blood leucocytes of 23 unrelated DLA-D homozygous dogs representing nine DLA-D types (defined by mixed leucocyte reaction) was digested with restriction enzymes (BamHI, EcoRI, Hind III, Pvu II, Taq I, Rsa I, Msp I, Pst I and Bgl II), separated by agarose gel electrophoresis and transferred onto Biotrace membrane. The Southern blots were successively hybridized with radiolabelled HLA cDNA probes corresponding to DQ, DP, DZ and DR alpha genes. Clear evidence was obtained for the canine homologues of DQ and DR alpha genes with simple bi- or tri-allelic polymorphism respectively. Evidence for a single, nonpolymorphic DP alpha gene was also obtained. However, the presence of a DZ alpha gene could not be clearly demonstrated in canine genomic DNA. This report extends our previous RFLP analysis documenting polymorphism of DLA class II beta genes in the same panel of homozygous typing cell dogs, and provides the basis for DLA-D genotyping at a population level. This study also characterizes the RFLP-defined preferential allelic associations across the DLA-D region in nine different homozygous typing cell specificities.

Restriction fragment length polymorphism of the major histocompatibility complex of the dog.

PubMed

Sarmiento, U M; Storb, R F

1988-01-01

Human major histocompatibility complex (HLA) cDNA probes were used to analyze the restriction fragment length polymorphism (RFLP) of the DLA-D region in dogs. Genomic DNA from peripheral blood leucocytes of 23 unrelated DLA-D-homozygous dogs representing nine DLA-D types (defined by mixed leucocyte reaction) was digested with restriction enzymes (Bam HI, Eco RI, Hind III, Pvu II, Taq I, Rsa I, Msp I, Pst I, and Bgl II), separated by agarose gel electrophoresis, and transferred onto Biotrace membrane. The Southern blots were successively hybridized with radiolabeled HLA cDNA probes corresponding to DR, DQ, DP, and DO beta genes. The autoradiograms for all nine enzyme digests displayed multiple bands with the DRb, DQb, and DPb probes while the DOb probe hybridized with one to two bands. The RFLP patterns were highly polymorphic but consistent within each DLA-D type. Standard RFLP patterns were established for nine DLA-D types which could be discriminated from each other by using two enzymes (Rsa I and Pst I) and the HLA-DPb probe. Cluster analysis of the polymorphic restriction fragments detected by the DRb probe revealed four closely related supertypic groups or DLA-DR families: Dw3 + Dw4 + D1, Dw8 + D10, D7 + D16 + D9, and Dw1. This study provides the basis for DLA-D genotyping at a population level by RFLP analysis. These results also suggest that the genetic organization of the DLA-D region may closely resemble that of the HLA complex.

77 FR 72335 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-05

... computer networks, systems, or databases. The records contain the individual's name; social security number... control and track access to DLA-controlled networks, computer systems, and databases. The records may also...

HPC Programming on Intel Many-Integrated-Core Hardware with MAGMA Port to Xeon Phi

DOE PAGES

Dongarra, Jack; Gates, Mark; Haidar, Azzam; ...

2015-01-01

This paper presents the design and implementation of several fundamental dense linear algebra (DLA) algorithms for multicore with Intel Xeon Phi coprocessors. In particular, we consider algorithms for solving linear systems. Further, we give an overview of the MAGMA MIC library, an open source, high performance library, that incorporates the developments presented here and, more broadly, provides the DLA functionality equivalent to that of the popular LAPACK library while targeting heterogeneous architectures that feature a mix of multicore CPUs and coprocessors. The LAPACK-compliance simplifies the use of the MAGMA MIC library in applications, while providing them with portably performant DLA.more » High performance is obtained through the use of the high-performance BLAS, hardware-specific tuning, and a hybridization methodology whereby we split the algorithm into computational tasks of various granularities. Execution of those tasks is properly scheduled over the heterogeneous hardware by minimizing data movements and mapping algorithmic requirements to the architectural strengths of the various heterogeneous hardware components. Our methodology and programming techniques are incorporated into the MAGMA MIC API, which abstracts the application developer from the specifics of the Xeon Phi architecture and is therefore applicable to algorithms beyond the scope of DLA.« less

41 CFR 101-30.503 - Maintenance actions required.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., the agency shall submit data to GSA, the Defense Logistics Agency (DLA), the Veterans Administration... submission to DLSC, except that civilian agencies receiving supply support on an item from a DLA center or... DLA center using DD Form 1685, Data Exchange and/or Proposed Revision of Catalog Data, or to the VA...

41 CFR 101-30.503 - Maintenance actions required.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., the agency shall submit data to GSA, the Defense Logistics Agency (DLA), the Veterans Administration... submission to DLSC, except that civilian agencies receiving supply support on an item from a DLA center or... DLA center using DD Form 1685, Data Exchange and/or Proposed Revision of Catalog Data, or to the VA...

41 CFR 101-30.503 - Maintenance actions required.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., the agency shall submit data to GSA, the Defense Logistics Agency (DLA), the Veterans Administration... submission to DLSC, except that civilian agencies receiving supply support on an item from a DLA center or... DLA center using DD Form 1685, Data Exchange and/or Proposed Revision of Catalog Data, or to the VA...

41 CFR 101-30.503 - Maintenance actions required.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., the agency shall submit data to GSA, the Defense Logistics Agency (DLA), the Veterans Administration... submission to DLSC, except that civilian agencies receiving supply support on an item from a DLA center or... DLA center using DD Form 1685, Data Exchange and/or Proposed Revision of Catalog Data, or to the VA...

48 CFR 52.211-2 - Availability of Specifications, Standards, and Data Item Descriptions Listed in the Acquisition...

Code of Federal Regulations, 2010 CFR

2010-10-01

... ASSIST websites: (1) ASSIST (http://assist.daps.dla.mil); (2) Quick Search (http://assist.daps.dla.mil/quicksearch); (3) ASSISTdocs.com (http://assistdocs.com). (b) Documents not available from ASSIST may be... Wizard (http://assist.daps.dla.mil/wizard); (2) Phoning the DoDSSP Customer Service Desk (215) 697-2179...

Diagnosing Diagnostic Language Assessment

ERIC Educational Resources Information Center

Lee, Yong-Won

2015-01-01

Diagnostic language assessment (DLA) is gaining a lot of attention from language teachers, testers, and applied linguists. With a recent surge of interest in DLA, there seems to be an urgent need to assess where the field of DLA stands at the moment and develop a general sense of where it should be moving in the future. The current article, as the…

48 CFR 52.211-2 - Availability of Specifications, Standards, and Data Item Descriptions Listed in the Acquisition...

Code of Federal Regulations, 2011 CFR

2011-10-01

... ASSIST websites: (1) ASSIST (http://assist.daps.dla.mil); (2) Quick Search (http://assist.daps.dla.mil/quicksearch); (3) ASSISTdocs.com (http://assistdocs.com). (b) Documents not available from ASSIST may be... Wizard (http://assist.daps.dla.mil/wizard); (2) Phoning the DoDSSP Customer Service Desk (215) 697-2179...

48 CFR 52.211-2 - Availability of Specifications, Standards, and Data Item Descriptions Listed in the Acquisition...

Code of Federal Regulations, 2014 CFR

2014-10-01

... ASSIST websites: (1) ASSIST (https://assist.dla.mil/online/start/; (2) Quick Search (http://quicksearch.dla.mil/; (3) ASSISTdocs.com (http://assistdocs.com). (b) Documents not available from ASSIST may be... Wizard (https://assist.dla.mil/wizard/index.cfm); (2) Phoning the DoDSSP Customer Service Desk (215) 697...

48 CFR 52.211-2 - Availability of Specifications, Standards, and Data Item Descriptions Listed in the Acquisition...

Code of Federal Regulations, 2013 CFR

2013-10-01

... ASSIST websites: (1) ASSIST (http://assist.daps.dla.mil); (2) Quick Search (http://assist.daps.dla.mil/quicksearch); (3) ASSISTdocs.com (http://assistdocs.com). (b) Documents not available from ASSIST may be... Wizard (http://assist.daps.dla.mil/wizard); (2) Phoning the DoDSSP Customer Service Desk (215) 697-2179...

48 CFR 52.211-2 - Availability of Specifications, Standards, and Data Item Descriptions Listed in the Acquisition...

Code of Federal Regulations, 2012 CFR

2012-10-01

... ASSIST websites: (1) ASSIST (http://assist.daps.dla.mil); (2) Quick Search (http://assist.daps.dla.mil/quicksearch); (3) ASSISTdocs.com (http://assistdocs.com). (b) Documents not available from ASSIST may be... Wizard (http://assist.daps.dla.mil/wizard); (2) Phoning the DoDSSP Customer Service Desk (215) 697-2179...

Detection Of DLA Candidate Galaxies Towards PKS 1756+237 And Q 0551-366 At z=1.67,1.96

NASA Astrophysics Data System (ADS)

Wong, Andre; Roth, K.

2007-12-01

We present the results of an adaptive optics imaging search for damped Lyman-α galaxies near the vicinity of quasars PKS 1756+237 and Q 0551-366. Prior spectral studies have detected damped Lyman-α or strong metal line absorption in the spectra of the two quasars corresponding to redshifts of z=1.67 and z=1.96, respectively. Both these systems are distinctive due to the confirmed detections of C I absorption, with molecular H also present in the spectra of the DLA towards Q 0551-366. Data was obtained in October 2001 and April 2002 using the University of Hawaii (IfA) Hokupa'a/QUIRC 36-element curvature AO system at Gemini North Observatory. The Hokupa'a AO system allowed users to guide on faint guide stars ( 17.5 mag), with a resulting resolution of 0.26” in the imaging data presented here. We have identified candidate DLA galaxies toward each of the quasars. The candidate for PKS 1756+237 is well separated from the quasar, while the Q 0551-366 candidate is only apparent after PSF subtraction. The Gemini Observatory is operated by the AURA, Inc. , under a cooperative agreement with the NSF on behalf of the Gemini partnership.

Complete multipactor suppression in an X-band dielectric-loaded accelerating structure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jing, C.; Gold, S. H.; Fischer, Richard

2016-05-09

Multipactor is a major issue limiting the gradient of rf-driven Dielectric-Loaded Accelerating (DLA) structures. Theoretical models have predicted that an axial magnetic field applied to DLA structures may completely block the multipactor discharge. However, previous attempts to demonstrate this magnetic field effect in an X-band traveling-wave DLA structure were inconclusive, due to the axial variation of the applied magnetic field, and showed only partial suppression of the multipactor loading [Jing et al., Appl. Phys. Lett. 103, 213503 (2013)]. The present experiment has been performed under improved conditions with a uniform axial magnetic field extending along the length of an X-bandmore » standing-wave DLA structure. Multipactor loading began to be continuously reduced starting from 3.5 kG applied magnetic field and was completely suppressed at 8 kG. Dependence of multipactor suppression on the rf gradient inside the DLA structure was also measured.« less

Experimental signatures of direct-laser-acceleration-assisted laser wakefield acceleration

NASA Astrophysics Data System (ADS)

Shaw, J. L.; Lemos, N.; Marsh, K. A.; Froula, D. H.; Joshi, C.

2018-04-01

The direct laser acceleration (DLA) of electrons in a laser wakefield accelerator (LWFA) operating in the forced or quasi-blowout regimes has been investigated through experiment and simulation. When there is a significant overlap between the trapped electrons and the drive laser in a LWFA cavity, the resulting electrons can gain energy from both the LWFA and the DLA mechanisms. Experimental work investigates the properties of the electron beams produced in a LWFA with ionization injection by dispersing those beams in the direction perpendicular to the laser polarization. These electron beams show certain spectral features that are characteristic of DLA. These characteristic features are reproduced using particle-in-cell simulations, where particle tracking was used to elucidate the roles of LWFA and DLA to the energy gain of the electrons in this experimental regime and to demonstrate that such spectral features are definitive signatures of the presence of DLA in LWFA.

GIANT METREWAVE RADIO TELESCOPE DETECTION OF TWO NEW H I 21 cm ABSORBERS AT z ≈ 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kanekar, N., E-mail: nkanekar@ncra.tifr.res.in

2014-12-20

I report the detection of H I 21 cm absorption in two high column density damped Lyα absorbers (DLAs) at z ≈ 2 using new wide-band 250-500 MHz receivers on board the Giant Metrewave Radio Telescope. The integrated H I 21 cm optical depths are 0.85 ± 0.16 km s{sup –1} (TXS1755+578) and 2.95 ± 0.15 km s{sup –1} (TXS1850+402). For the z = 1.9698 DLA toward TXS1755+578, the difference in H I 21 cm and C I profiles and the weakness of the radio core suggest that the H I 21cm absorption arises toward radio components in the jet,more » and that the optical and radio sightlines are not the same. This precludes an estimate of the DLA spin temperature. For the z = 1.9888 DLA toward TXS1850+402, the absorber covering factor is likely to be close to unity, as the background source is extremely compact, with the entire 5 GHz emission arising from a region of ≤ 1.4 mas in size. This yields a DLA spin temperature of T{sub s} = (372 ± 18) × (f/1.0) K, lower than typical T{sub s} values in high-z DLAs. This low spin temperature and the relatively high metallicity of the z = 1.9888 DLA ([Zn/H] =(– 0.68 ± 0.04)) are consistent with the anti-correlation between metallicity and spin temperature that has been found earlier in damped Lyα systems.« less

Relationships between visual field sensitivity and spectral absorption properties of the neuroretinal rim in glaucoma by multispectral imaging.

PubMed

Denniss, Jonathan; Schiessl, Ingo; Nourrit, Vincent; Fenerty, Cecilia H; Gautam, Ramesh; Henson, David B

2011-11-07

To investigate the relationship between neuroretinal rim (NRR) differential light absorption (DLA, a measure of spectral absorption properties) and visual field (VF) sensitivity in primary open-angle glaucoma (POAG). Patients diagnosed with (n = 22) or suspected of having (n = 7) POAG were imaged with a multispectral system incorporating a modified digital fundus camera, 250-W tungsten-halogen lamp, and fast-tuneable liquid crystal filter. Five images were captured sequentially within 1.0 second at wavelengths selected according to absorption properties of hemoglobin (range, 570-610 nm), and a Beer-Lambert law model was used to produce DLA maps of residual NRR from the images. Patients also underwent VF testing. Differences in NRR DLA in vertically opposing 180° and 45° sectors either side of the horizontal midline were compared with corresponding differences in VF sensitivity on both decibel and linear scales by Spearman's rank correlation. The decibel VF sensitivity scale showed significant relationships between superior-inferior NRR DLA difference and sensitivity differences between corresponding VF areas in 180° NRR sectors (Spearman ρ = 0.68; P < 0.0001), superior-/inferior-temporal 45° NRR sectors (ρ = 0.57; P < 0.002), and superior-/inferior-nasal 45° NRR sectors (ρ = 0.59; P < 0.001). Using the linear VF sensitivity scale significant relationships were found for 180° NRR sectors (ρ = 0.62; P < 0.0002) and superior-inferior-nasal 45° NRR sectors (ρ = 0.53; P < 0.002). No significant difference was found between correlations using the linear or decibel VF sensitivity scales. Residual NRR DLA is related to VF sensitivity in POAG. Multispectral imaging may provide clinically important information for the assessment and management of POAG.

Relationships between Visual Field Sensitivity and Spectral Absorption Properties of the Neuroretinal Rim in Glaucoma by Multispectral Imaging

PubMed Central

Denniss, Jonathan; Schiessl, Ingo; Nourrit, Vincent; Fenerty, Cecilia H.; Gautam, Ramesh; Henson, David B.

2011-01-01

Purpose. To investigate the relationship between neuroretinal rim (NRR) differential light absorption (DLA, a measure of spectral absorption properties) and visual field (VF) sensitivity in primary open-angle glaucoma (POAG). Methods. Patients diagnosed with (n = 22) or suspected of having (n = 7) POAG were imaged with a multispectral system incorporating a modified digital fundus camera, 250-W tungsten-halogen lamp, and fast-tuneable liquid crystal filter. Five images were captured sequentially within 1.0 second at wavelengths selected according to absorption properties of hemoglobin (range, 570–610 nm), and a Beer-Lambert law model was used to produce DLA maps of residual NRR from the images. Patients also underwent VF testing. Differences in NRR DLA in vertically opposing 180° and 45° sectors either side of the horizontal midline were compared with corresponding differences in VF sensitivity on both decibel and linear scales by Spearman's rank correlation. Results. The decibel VF sensitivity scale showed significant relationships between superior–inferior NRR DLA difference and sensitivity differences between corresponding VF areas in 180° NRR sectors (Spearman ρ = 0.68; P < 0.0001), superior-/inferior-temporal 45° NRR sectors (ρ = 0.57; P < 0.002), and superior-/inferior-nasal 45° NRR sectors (ρ = 0.59; P < 0.001). Using the linear VF sensitivity scale significant relationships were found for 180° NRR sectors (ρ = 0.62; P < 0.0002) and superior–inferior–nasal 45° NRR sectors (ρ = 0.53; P < 0.002). No significant difference was found between correlations using the linear or decibel VF sensitivity scales. Conclusions. Residual NRR DLA is related to VF sensitivity in POAG. Multispectral imaging may provide clinically important information for the assessment and management of POAG. PMID:21980002

Logistics as a Competitive Warfighting Advantage

DTIC Science & Technology

2016-10-20

World Class Business Practices DoD Application 1 Focused on Core Functions Define and focus on core functions; Divest other...primes and lower cost timelines  DLA Leadership Model – Aligning DLA leadership to business standards  Defense Working Capital Fund - DLA...DLA’s leadership should incorporate private business sector structures – Leadership incentive structures are not reflective of private business best

32 CFR 621.1 - Loan of Army/Defense Logistics Agency (DLA) owned property for use at national and State...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Loan of Army/Defense Logistics Agency (DLA) owned... of Army/Defense Logistics Agency (DLA) owned property for use at national and State conventions. (a... will be submitted to the appropriate CONUS Army Commander of the area in which the convention will be...

32 CFR 621.1 - Loan of Army/Defense Logistics Agency (DLA) owned property for use at national and State...

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 3 2014-07-01 2014-07-01 false Loan of Army/Defense Logistics Agency (DLA... § 621.1 Loan of Army/Defense Logistics Agency (DLA) owned property for use at national and State... will be submitted to the appropriate CONUS Army Commander of the area in which the convention will be...

32 CFR 621.1 - Loan of Army/Defense Logistics Agency (DLA) owned property for use at national and State...

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 3 2013-07-01 2013-07-01 false Loan of Army/Defense Logistics Agency (DLA... § 621.1 Loan of Army/Defense Logistics Agency (DLA) owned property for use at national and State... will be submitted to the appropriate CONUS Army Commander of the area in which the convention will be...

32 CFR 621.1 - Loan of Army/Defense Logistics Agency (DLA) owned property for use at national and State...

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 3 2012-07-01 2009-07-01 true Loan of Army/Defense Logistics Agency (DLA) owned... of Army/Defense Logistics Agency (DLA) owned property for use at national and State conventions. (a... will be submitted to the appropriate CONUS Army Commander of the area in which the convention will be...

32 CFR 621.1 - Loan of Army/Defense Logistics Agency (DLA) owned property for use at national and State...

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 3 2011-07-01 2009-07-01 true Loan of Army/Defense Logistics Agency (DLA) owned... of Army/Defense Logistics Agency (DLA) owned property for use at national and State conventions. (a... will be submitted to the appropriate CONUS Army Commander of the area in which the convention will be...

32 CFR Appendix H to Part 323 - DLA Exemption Rules

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false DLA Exemption Rules H Appendix H to Part 323... PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM Pt. 323, App. H Appendix H to Part 323—DLA Exemption...) through (4), (e)(1), (e)(4)(G), (H), and (I), and (f). 3. Authorities: 5 U.S.C. 552a(k)(2) and (k)(5). 4...

Breed differences in development of anti-insulin antibodies in diabetic dogs and investigation of the role of dog leukocyte antigen (DLA) genes.

PubMed

Holder, Angela L; Kennedy, Lorna J; Ollier, William E R; Catchpole, Brian

2015-10-15

Administration of insulin for treatment of diabetes mellitus in dogs can stimulate an immune response, with a proportion of animals developing anti-insulin antibodies (AIA). For an IgG antibody response to occur, this would require B cell presentation of insulin peptides by major histocompatibility complex (MHC) class II molecules, encoded by dog leukocyte antigen (DLA) genes, in order to receive T-cell help for class switching. DLA genes are highly polymorphic in the dog population and vary from breed to breed. The aim of the present study was to evaluate AIA reactivity in diabetic dogs of different breeds and to investigate whether DLA genes influence AIA status. Indirect ELISA was used to determine serological reactivity to insulin in diabetic dogs, treated with either a porcine or bovine insulin preparation. DLA haplotypes for diabetic dogs were determined by sequence-based typing of DLA-DRB1, -DQA1 and -DQB1 loci. Significantly greater insulin reactivity was seen in treated diabetic dogs (n=942) compared with non-diabetic dogs (n=100). Relatively few newly diagnosed diabetic dogs (3/109) were found to be AIA positive, although this provides evidence that insulin autoantibodies might be involved in the pathogenesis of the disease in some cases. Of the diabetic dogs treated with a bovine insulin preparation, 52.3% (182/348) were AIA positive, compared with 12.6% (75/594) of dogs treated with a porcine insulin preparation, suggesting that bovine insulin is more immunogenic. Breeds such as dachshund, Cairn terrier, miniature schnauzer and Tibetan terrier were more likely to develop AIA, whereas cocker spaniels were less likely to develop AIA, compared with crossbreed dogs. In diabetic dogs, DLA haplotype DRB1*0015--DQA1*006--DQB1*023 was associated with being AIA positive, whereas the haplotype DLA-DRB1*006--DQA1*005--DQB1*007 showed an association with being AIA negative. These research findings suggest that DLA genes influence AIA responses in treated diabetic dogs. Copyright © 2015 Elsevier B.V. All rights reserved.

Observation of multipactor suppression in a dielectric-loaded accelerating structure using an applied axial magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jing, C.; Konecny, R.; Antipov, S.

2013-11-18

Efforts by a number of institutions to develop a Dielectric-Loaded Accelerating (DLA) structure capable of supporting high gradient acceleration when driven by an external radio frequency source have been ongoing over the past decade. Single surface resonant multipactor has been previously identified as one of the major limitations on the practical application of DLA structures in electron accelerators. In this paper, we report the results of an experiment that demonstrated suppression of multipactor growth in an X-band DLA structure through the use of an applied axial magnetic field. This represents an advance toward the practical use of DLA structures inmore » many accelerator applications.« less

Calculating the radiation characteristics of accelerated electrons in laser-plasma interactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, X. F.; Graduate School of Engineering, Utsunomiya University, 7-1-2 Yohtoh, Utsunomiya 321-8585; Yu, Q.

2016-03-15

In this paper, we studied the characteristics of radiation emitted by electrons accelerated in a laser–plasma interaction by using the Lienard–Wiechert field. In the interaction of a laser pulse with a underdense plasma, electrons are accelerated by two mechanisms: direct laser acceleration (DLA) and laser wakefield acceleration (LWFA). At the beginning of the process, the DLA electrons emit most of the radiation, and the DLA electrons emit a much higher peak photon energy than the LWFA electrons. As the laser–plasma interaction progresses, the LWFA electrons become the major radiation emitter; however, even at this stage, the contribution from DLA electronsmore » is significant, especially to the peak photon energy.« less

The Mean Metal-line Absorption Spectrum of Damped Ly α Systems in BOSS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mas-Ribas, Lluís; Miralda-Escudé, Jordi; Pérez-Ràfols, Ignasi

We study the mean absorption spectrum of the Damped Ly α (DLA) population at z ∼ 2.6 by stacking normalized, rest-frame-shifted spectra of ∼27,000 DLA systems from the DR12 of the Baryon Oscillation Spectroscopic Survey (BOSS)/SDSS-III. We measure the equivalent widths of 50 individual metal absorption lines in five intervals of DLA hydrogen column density, five intervals of DLA redshift, and overall mean equivalent widths for an additional 13 absorption features from groups of strongly blended lines. The mean equivalent width of low-ionization lines increases with N {sub H} {sub i}, whereas for high-ionization lines the increase is much weaker.more » The mean metal line equivalent widths decrease by a factor ∼1.1–1.5 from z ∼ 2.1 to z ∼ 3.5, with small or no differences between low- and high-ionization species. We develop a theoretical model, inspired by the presence of multiple absorption components observed in high-resolution spectra, to infer mean metal column densities from the equivalent widths of partially saturated metal lines. We apply this model to 14 low-ionization species and to Al iii, S iii, Si iii, C iv, Si iv, N v, and O vi. We use an approximate derivation for separating the equivalent width contributions of several lines to blended absorption features, and infer mean equivalent widths and column densities from lines of the additional species N i, Zn ii, C ii*, Fe iii, and S iv. Several of these mean column densities of metal lines in DLAs are obtained for the first time; their values generally agree with measurements of individual DLAs from high-resolution, high signal-to-noise ratio spectra when they are available.« less

DLA-X Total Quality Management (TQM) Implementation Plan

DTIC Science & Technology

1989-07-01

PAGES TOM (Total Quality Management ), Continuous Process Improvement.( .) 4L-- Administration 16. PRICE CODE 17. SECURITY CLASSIFICATION 18. SECURITY...NSN 7540-01-280-5500 Standard Form 298 (Rev. 2-89) Pr.-cr,bed by ANSI Std ,,fl.f 296-102 DLA-X TOTAL QUALITY MANAGEMENT (TQM) IMPLEMENTATION PLAN o...application of proven Total Quality Management techniques. Quality Policy: Responsibility for quality is delegated to every employee ;11 DLA-X. Every

77 FR 27740 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-11

... storage media''. Retrievability: Delete ``and Social Security Number''. Safeguards: Delete last sentence...: * * * * * Categories of individuals covered by the system: Delete entry and replace with ``Children and their sponsors... admission to, DLA-managed day care facilities.'' Categories of records in the system: Delete ``Social...

32 CFR 323.4 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.4 Responsibilities. (a) General Counsel. The General Counsel, DLA, under the authority of the Director, Defense Logistics Agency: (1) Implements the DLA...

76 FR 73602 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

...; System of Records AGENCY: Defense Logistics Agency, Department of Defense (DoD). ACTION: Notice to amend a system of records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records...: Ms. Jody Sinkler, DLA FOIA/Privacy Act Office, Headquarters, Defense Logistics Agency, ATTN: DGA...

Unveiling the Secrets of Metallicity and Massive Star Formation Using DLAs Along Gamma-Ray Bursts

NASA Technical Reports Server (NTRS)

Cucchiara, A.; Fumagalli, M.; Rafelski, M.; Kocevski, D.; Prochaska, J. X.; Cooke, R. J.; Becker, G. D.

2015-01-01

We present the largest, publicly available, sample of Damped Lyman-alpha systems (DLAs) along Swift discovered Gamma-ray Bursts (GRB) line of sights in order to investigate the environmental properties of long GRB hosts in the z = 1.8 - 6 redshift range. Compared with the most recent quasar DLAs sample (QSO-DLA), our analysis shows that GRB-DLAs probe a more metal enriched environment at z approximately greater than 3, up to [X/H] approximately -0.5. In the z = 2 - 3 redshift range, despite the large number of lower limits, there are hints that the two populations may be more similar (only at 90% significance level) than at higher redshifts. Also, at high-z, the GRB-DLA average metallicity seems to decline at a shallower rate than the QSO-DLAs: GRB-DLA hosts may be polluted with metals at least as far as approximately 2 kpc from the GRB explosion site, probably due to previous star-formation episodes and/or supernovae explosions. This shallow metallicity trend, extended now up to z approximately 5, confirms previous results that GRB hosts are star-forming and have, on average, higher metallicity than the general QSO-DLA population. Finally, our host metallicity measurements are broadly consistent with the predictions derived from the hypothesis of two channels of GRB progenitors, one of which is mildly affected by a metallicity bias, although more data are needed to constrain the models at z approximately greater than 4.

Total Quality Management Implementation Plan: DLA-N

DTIC Science & Technology

1989-07-01

e Wastimto , n. Othe 20 Seato3 4. TITLE AND SUBTITLE S. FUNDING NUMBERS DLA-N Total Quality Management 6. AUTHOR(S) 7. PERFORMING ORGANIZATION NAME(S...PAGES TQM (Total Quality Management ), Continuous Process Improvement.(; , Defense National Stockpile 16. PRICE CODEI17. SECURITY CLASSIFICATION 18...IUNCLASSIFIED UL NSN 7540-01-280-5500 Standard Form 298 (Rev. 2-89) pr"!Cbed ty ANSI Std Z39’B6 296-102 DLA - N TOTAL QUALITY MANAGEMENT IMPLEMENTATION PLAN I

Metabolic engineering and adaptive evolution for efficient production of D-lactic acid in Saccharomyces cerevisiae.

PubMed

Baek, Seung-Ho; Kwon, Eunice Y; Kim, Yong Hwan; Hahn, Ji-Sook

2016-03-01

There is an increasing demand for microbial production of lactic acid (LA) as a monomer of biodegradable poly lactic acid (PLA). Both optical isomers, D-LA and L-LA, are required to produce stereocomplex PLA with improved properties. In this study, we developed Saccharomyces cerevisiae strains for efficient production of D-LA. D-LA production was achieved by expressing highly stereospecific D-lactate dehydrogenase gene (ldhA, LEUM_1756) from Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 in S. cerevisiae lacking natural LA production activity. D-LA consumption after glucose depletion was inhibited by deleting DLD1 encoding D-lactate dehydrogenase and JEN1 encoding monocarboxylate transporter. In addition, ethanol production was reduced by deleting PDC1 and ADH1 genes encoding major pyruvate decarboxylase and alcohol dehydrogenase, respectively, and glycerol production was eliminated by deleting GPD1 and GPD2 genes encoding glycerol-3-phosphate dehydrogenase. LA tolerance of the engineered D-LA-producing strain was enhanced by adaptive evolution and overexpression of HAA1 encoding a transcriptional activator involved in weak acid stress response, resulting in effective D-LA production up to 48.9 g/L without neutralization. In a flask fed-batch fermentation under neutralizing condition, our evolved strain produced 112.0 g/L D-LA with a yield of 0.80 g/g glucose and a productivity of 2.2 g/(L · h).

48 CFR 51.101 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Policy. 51.101 Section 51.101 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT USE OF... Defense Logistics Agency (DLA), the General Services Administration (GSA), and the Department of Veterans...

A lab-on-chip for biothreat detection using single-molecule DNA mapping.

PubMed

Meltzer, Robert H; Krogmeier, Jeffrey R; Kwok, Lisa W; Allen, Richard; Crane, Bryan; Griffis, Joshua W; Knaian, Linda; Kojanian, Nanor; Malkin, Gene; Nahas, Michelle K; Papkov, Vyacheslav; Shaikh, Saad; Vyavahare, Kedar; Zhong, Qun; Zhou, Yi; Larson, Jonathan W; Gilmanshin, Rudolf

2011-03-07

Rapid, specific, and sensitive detection of airborne bacteria, viruses, and toxins is critical for biodefense, yet the diverse nature of the threats poses a challenge for integrated surveillance, as each class of pathogens typically requires different detection strategies. Here, we present a laboratory-on-a-chip microfluidic device (LOC-DLA) that integrates two unique assays for the detection of airborne pathogens: direct linear analysis (DLA) with unsurpassed specificity for bacterial threats and Digital DNA for toxins and viruses. The LOC-DLA device also prepares samples for analysis, incorporating upstream functions for concentrating and fractionating DNA. Both DLA and Digital DNA assays are single molecule detection technologies, therefore the assay sensitivities depend on the throughput of individual molecules. The microfluidic device and its accompanying operation protocols have been heavily optimized to maximize throughput and minimize the loss of analyzable DNA. We present here the design and operation of the LOC-DLA device, demonstrate multiplex detection of rare bacterial targets in the presence of 100-fold excess complex bacterial mixture, and demonstrate detection of picogram quantities of botulinum toxoid.

48 CFR 8.703 - Procurement list.

Code of Federal Regulations, 2012 CFR

2012-10-01

... the General Services Administration (GSA) Supply Catalog and GSA's Customer Service Center Catalogs... Defense Logistics Agency (DLA) and the Department of Veterans Affairs (VA). GSA, DLA, and VA are central...

Quasar 2175 Å dust absorbers - II. Correlation analysis and relationship with other absorption line systems

NASA Astrophysics Data System (ADS)

Ma, Jingzhe; Ge, Jian; Prochaska, J. Xavier; Zhang, Shaohua; Ji, Tuo; Zhao, Yinan; Zhou, Hongyan; Lu, Honglin; Schneider, Donald P.

2018-03-01

We present the cold neutral content (H I and C I gas) of 13 quasar 2175 Å dust absorbers (2DAs) at z = 1.6-2.5 to investigate the correlation between the presence of the UV extinction bump with other physical characteristics. These 2DAs were initially selected from the Sloan Digital Sky Surveys I-III and followed up with the Keck-II telescope and the Multiple Mirror Telescope as detailed in our Paper I. We perform a correlation analysis between metallicity, redshift, depletion level, velocity width, and explore relationships between 2DAs and other absorption line systems. The 2DAs on average have higher metallicity, higher depletion levels, and larger velocity widths than Damped Lyman α absorbers (DLAs) or subDLAs. The correlation between [Zn/H] and [Fe/Zn] or [Zn/H] and logΔV90 can be used as alternative stellar mass estimators based on the well-established mass-metallicity relation. The estimated stellar masses of the 2DAs in this sample are in the range of ˜109 to ˜2 × 1011 M⊙ with a median value of ˜2 × 1010 M⊙. The relationship with other quasar absorption line systems can be described as (1) 2DAs are a subset of Mg II and Fe II absorbers, (2) 2DAs are preferentially metal-strong DLAs/subDLAs, (3) More importantly, all of the 2DAs show C I detections with logN(C I) > 14.0 cm-2, and (4) 2DAs can be used as molecular gas tracers. Their host galaxies are likely to be chemically enriched, evolved, massive (more massive than typical DLA/subDLA galaxies), and presumably star-forming galaxies.

48 CFR 4.1801 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... States or its outlying areas by the Defense Logistics Agency (DLA) Contractor and Government Entity (CAGE... outside the United States and its outlying areas that the DLA Contractor and Government Entity (CAGE...

48 CFR 8.703 - Procurement list.

Code of Federal Regulations, 2011 CFR

2011-10-01

... identified in the General Services Administration (GSA) Supply Catalog and GSA's Customer Service Center... the Defense Logistics Agency (DLA) and the Department of Veterans Affairs (VA). GSA, DLA, and VA are...

48 CFR 8.703 - Procurement list.

Code of Federal Regulations, 2010 CFR

2010-10-01

... identified in the General Services Administration (GSA) Supply Catalog and GSA's Customer Service Center... the Defense Logistics Agency (DLA) and the Department of Veterans Affairs (VA). GSA, DLA, and VA are...

Followup Audit: DLA Officials Took Appropriate Actions to Address Concerns With Repair Parts for the High Mobility Multipurpose Wheeled Vehicle

DTIC Science & Technology

2016-04-29

Followup Audit : DLA Officials Took Appropriate Actions to Address Concerns With Repair Parts for the High Mobility Multipurpose Wheeled Vehicle A P R I L...Results in Brief Followup Audit : DLA Officials Took Appropriate Actions to Address Concerns With Repair Parts for the High Mobility Multipurpose Wheeled...and Maritime Paid Too Much for High Mobility Multipurpose Wheeled Vehicle Repair Parts,” (HMMWV) was issued on April 4, 2014. The audit

Defense Inventory: Defense Logistics Agency Needs to Expand on Efforts to More Effectively Manage Spare Parts

DTIC Science & Technology

2010-05-01

Government Accountability Office Washington, DC 20548 May 11, 2010 The Honorable Solomon P. Ortiz Chairman The Honorable J . Randy Forbes...those levels in its reorder point calculus . 12A purchase request is a requisition for an item that has not yet been placed on order. A purchase...mean that DLA is being wasteful. They asserted that DLA strives to be a good steward of government resources. However, without such metrics, DLA cannot

Two separable functional domains of simian virus 40 large T antigen: carboxyl-terminal region of simian virus 40 large T antigen is required for efficient capsid protein synthesis.

PubMed Central

Tornow, J; Polvino-Bodnar, M; Santangelo, G; Cole, C N

1985-01-01

The carboxyl-terminal portion of simian virus 40 large T antigen is essential for productive infection of CV-1 and CV-1p green monkey kidney cells. Mutant dlA2459, lacking 14 base pairs at 0.193 map units, was positive for viral DNA replication, but unable to form plaques in CV-1p cells (J. Tornow and C.N. Cole, J. Virol. 47:487-494, 1983). In this report, the defect of dlA2459 is further defined. Simian virus 40 late mRNAs were transcribed, polyadenylated, spliced, and transported in dlA2459-infected cells, but the level of capsid proteins produced in infected CV-1 green monkey kidney cells was extremely low. dlA2459 large T antigen lacks those residues known to be required for adenovirus helper function, and the block to productive infection by dlA2459 occurs at the same stage of infection as the block to productive adenovirus infection of CV-1 cells. These results suggest that the adenovirus helper function is required for productive infection by simian virus 40. Mutant dlA2459 was able to grow on the Vero and BSC-1 lines of African green monkey kidney cells. Additional mutants affecting the carboxyl-terminal portion of large T were prepared. Mutant inv2408 contains an inversion of the DNA between the BamHI and BclI sites (0.144 to 0.189 map units). This inversion causes transposition of the carboxyl-terminal 26 amino acids of large T antigen and the carboxyl-terminal 18 amino acids of VP1. This mutant was viable, even though the essential information absent from dlA2459 large T antigen has been transferred to the carboxyl terminus of VP1 of inv2408. The VP1 polypeptide carrying this carboxyl-terminal portion of large T could overcome the defect of dlA2459. This indicates that the carboxyl terminus of large T antigen is a separate and separable functional domain. Images PMID:2982029

Associations between gastric dilatation-volvulus in Great Danes and specific alleles of the canine immune-system genes DLA88, DRB1, and TLR5.

PubMed

Harkey, Michael A; Villagran, Alexandra M; Venkataraman, Gopalakrishnan M; Leisenring, Wendy M; Hullar, Meredith A J; Torok-Storb, Beverly J

2017-08-01

OBJECTIVE To determine whether specific alleles of candidate genes of the major histocompatibility complex (MHC) and innate immune system were associated with gastric dilatation-volvulus (GDV) in Great Danes. ANIMALS 42 healthy Great Danes (control group) and 39 Great Danes with ≥ 1 GDV episode. PROCEDURES Variable regions of the 2 most polymorphic MHC genes (DLA88 and DRB1) were amplified and sequenced from the dogs in each group. Similarly, regions of 3 genes associated with the innate immune system (TLR5, NOD2, and ATG16L1), which have been linked to inflammatory bowel disease, were amplified and sequenced. Alleles were evaluated for associations with GDV, controlling for age and dog family. RESULTS Specific alleles of genes DLA88, DRB1, and TLR5 were significantly associated with GDV. One allele of each gene had an OR > 2 in the unadjusted univariate analyses and retained a hazard ratio > 2 after controlling for temperament, age, and familial association in the multivariate analysis. CONCLUSIONS AND CLINICAL RELEVANCE The 3 GDV-associated alleles identified in this study may serve as diagnostic markers for identification of Great Danes at risk for GDV. Additional research is needed to determine whether other dog breeds have the same genetic associations. These findings also provided a new target for research into the etiology of, and potential treatments for, GDV in dogs.

78 FR 22854 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-17

... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DoD-2013-OS-0075] Privacy Act of 1974; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to alter a System of Records... Officer, Department of Defense. S190.10 System name: DLA Hometown News Releases (June 24, 2011; 76 FR...

76 FR 37082 - Privacy Act of 1974; Systems of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2011-OS-0068] Privacy Act of 1974; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice To Amend a System of Records..., Alternate OSD Federal Register Liaison Officer, Department of Defense. S190.10 System name: DLA Hometown...

76 FR 76149 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-06

...; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to Amend a System of Records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records notice in its existing...: Ms. Jody Sinkler at (703) 767-5045, or DLA FOIA/Privacy Act Office, Headquarters, Defense Logistics...

Limit Analysis of Geometrically Hardening Composite Steel-Concrete Systems / Stany Graniczne Geometrycznie Wzmacniających Się Konstrukcji Zespolonych

NASA Astrophysics Data System (ADS)

Alawdin, Piotr; Urbańska, Krystyna

2015-03-01

The paper considers some results of creating load-carrying composite systems that have uprated strength, rigidity and safety, and therefore are called geometrically (self-) hardening systems. The optimization mathematic models of structures as discrete mechanical systems withstanding dead load, monotonic or low cyclic static and kinematic actions are proposed. To find limit parameters of these actions the extreme energetic principle is suggested what result in the bilevel mathematic programming problem statement. The limit parameters of load actions are found on the first level of optimization. On the second level the power of the constant load with equilibrium preloading is maximized and/or system cost is minimized. The examples of using the proposed methods are presented and geometrically hardening composite steel-concrete system are taken into account. W pracy przedstawiono sposoby projektowania konstrukcji, które ze względu na swoją geometrię oraz topologię posiadają podwyższoną nośność, sztywność i bezpieczeństwo. Systemy takie nazwano geometrycznie (samo-) wzmacniającymi się. Zaproponowano optymalizacyjne modele matematyczne konstrukcji jako dyskretne systemy mechaniczne będące pod obciążeniem stałym, zmiennym monotoniczne lub niskocyklowym, statycznym lub kinematycznym. Dla znalezienia granicznych parametrów obciążeń wprowadzona została ekstremalna zasada energetyczna, przedstawiona jako problem dwupoziomowego programowania matematycznego. Graniczne parametry obciążeń szukane są na pierwszym poziomie optymalizacji. Na drugim poziomie minimalizowany jest koszt systemu i/lub maksymalizowana jest moc stałego równoważącego obciążenia z dociążeniem. Ponadto w pracy przeanalizowano numerycznie i analitycznie zachowanie konstrukcji geometrycznie wzmacniających się na przykładzie konstrukcji zespolonych stalowobetonowych. Pierwszy przykład dotyczy konstrukcji belkowo-prętowej z podciągiem, belkę stanowi stalowy dwuteownik połączony z płytą betonową. Analizowano cztery przypadki skratownia podciągu wykonanego z prętów stalowych o przekroju kołowym i znacznej sztywności słupów. Pokazano znaczący wpływ orientacji słupów podciągu na nośność konstrukcji. Drugi przykład numeryczny wykonano dla uproszczonego modelu wiaduktu WD-22 znajdującego się na węźle "Pyrzyce" na drodze ekspresowej S3. Dla obu przykładów realizowano dwa przypadki obciążania konstrukcji, bez uwzgłędnienia i z uwzgłędnieniem stałego równoważącego obciążenia z dociążeniem. Obliczenia numeryczne wykonano w środowisku systemu Abaqus/Standard stosując analizę geometrycznie nieliniową (Nlgeom). W obliczeniach przyjęto następujące modele materiałowe: dla belki żelbetowej - idealnie sprężysto-plastyczny natomiast dla prętów stalowych podciągu - sprężysty. Celem analizy była obserwacja zachowania się konstrukcji po osiągnięciu obciążenia granicznego dla różnych przypadków skratowania oraz oszacowanie nośności granicznej dla konstrukcji bez stałego obciążenia oraz ze stałym obciążeniem i dociążeniem. Na podstawie przeprowadzonych obliczeń numerycznych i analitycznych stwierdzono, że w różnych konstrukcjach o pewnych wymiarach skratowania obserwuje się wzmocnienie geometryczne po osiągnięciu przez system nośności granicznej. Uwzględnienie obciążenia stałego równoważącego oraz dodatkowego dociążenia powoduje wzrost nośności granicznej konstrukcji geometrycznie wzmacniających się o około 20 %.

48 CFR 52.204-17 - Ownership or Control of Offeror.

Code of Federal Regulations, 2014 CFR

2014-10-01

... its outlying areas by the Defense Logistics Agency (DLA) Contractor and Government Entity (CAGE... outside the United States and its outlying areas that the DLA Contractor and Government Entity (CAGE...

Safety of a picosecond laser with diffractive lens array (DLA) in the treatment of Fitzpatrick skin types IV to VI: A retrospective review.

PubMed

Haimovic, Adele; Brauer, Jeremy A; Cindy Bae, Yoon-Soo; Geronemus, Roy G

2016-05-01

Laser therapy in patients with skin of color is associated with an increased rate of complications. The 755-nm picosecond laser with the diffractive lens array (DLA) has been used for the treatment of scars, striae, and rejuvenation. By delivering high energy to focused areas, the DLA minimizes complications. This study explores the adverse events associated with treatment with the 755-nm picosecond laser with DLA in individuals with Fitzpatrick skin type IV to VI. A retrospective chart review of patients treated with the 755-nm picosecond laser with DLA with a standardized spot size of 6 mm, fluence of 0.71 J/cm(2), and pulse width of 750 to 850 picoseconds was performed. Standard clinical photographs were obtained before treatment and at follow-up. Treatment sites were assessed for dyspigmentation, erythema, edema, and herpetic lesions. A total of 56 patients with Fitzpatrick skin type IV to VI, atrophic and hypertrophic scars, and pigmented lesions or striae were included. Ten patients (17.9%) were lost to follow-up. Transient adverse events, most commonly erythema and hyperpigmentation, were reported after therapy; these resolved in all cases. Retrospective design is a limitation. The 755-nm picosecond laser with the DLA device may be a safe therapeutic alternative for unwanted scars, pigmented lesions, and striae in patients with skin of color. Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

48 CFR 552.211-92 - Radio Frequency Identification (RFID) using passive tags.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Logistics Agency (DLA) or Department of Defense (DoD) destinations. Shipments shall be tagged in accordance with 48 CFR clause 252.211-7006. Shipments to GSA Distribution Centers with final destinations to DLA...

48 CFR 552.211-92 - Radio Frequency Identification (RFID) using passive tags.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Logistics Agency (DLA) or Department of Defense (DoD) destinations. Shipments shall be tagged in accordance with 48 CFR clause 252.211-7006. Shipments to GSA Distribution Centers with final destinations to DLA...

48 CFR 552.211-92 - Radio Frequency Identification (RFID) using passive tags.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Logistics Agency (DLA) or Department of Defense (DoD) destinations. Shipments shall be tagged in accordance with 48 CFR clause 252.211-7006. Shipments to GSA Distribution Centers with final destinations to DLA...

Analysis of droplet transfer mode and forming process of weld bead in CO 2 laser-MAG hybrid welding process

NASA Astrophysics Data System (ADS)

Liu, Shuangyu; Liu, Fengde; Zhang, Hong; Shi, Yan

2012-06-01

In this paper, CO 2 laser-metal active gas (MAG) hybrid welding technique is used to weld high strength steel and the optimized process parameters are obtained. Using LD Pumped laser with an emission wavelength of 532 nm to overcome the strong interference from the welding arc, a computer-based system is developed to collect and visualize the waveforms of the electrical welding parameters and metal transfer processes in laser-MAG. The welding electric signals of hybrid welding processes are quantitatively described and analyzed using the ANALYSATOR HANNOVER. The effect of distance between laser and arc ( DLA) on weld bead geometry, forming process of weld shape, electric signals, arc characteristic and droplet transfer behavior is investigated. It is found that arc characteristic, droplet transfer mode and final weld bead geometry are strongly affected by the distance between laser and arc. The weld bead geometry is changed from "cocktail cup" to "cone-shaped" with the increasing DLA. The droplet transfer mode is changed from globular transfer to projected transfer with the increasing DLA. Projected transfer mode is an advantage for the stability of hybrid welding processes.

Association of canine juvenile generalized demodicosis with the dog leukocyte antigen system.

PubMed

It, V; Barrientos, L; López Gappa, J; Posik, D; Díaz, S; Golijow, C; Giovambattista, G

2010-07-01

Demodectic mange is a well-known parasitic skin disease characterized by the presence of a larger than normal number of Demodex mites (Demodex canis) in the skin of dogs. Recent research has suggested that major histocompatibility complex (MHC) class II expression is higher in the skin of dogs suffering from demodicosis than in normal ones. We have investigated whether canine Dog Leukocyte Antigen (DLA) class II alleles are associated with canine juvenile generalized demodicosis (JGD). In the present study, the analysis of microsatellite markers (FH2202, FH2975 and FH2054) linked to DLA was made in Boxer, Argentinean Mastiff and mixed breed dogs. DNA samples from 56 dogs affected with the disease and 60 breed-matched controls collected in Argentina were analysed. A highly significant association, in some of the analysed markers, in all breeds with the presence of demodicosis was observed with P < 0.05 and odds ratio (OR) > or =5. The results of this study suggest that an underlying DLA association exists with demodicosis in dogs and that this may represent an important immunological risk factor in the aetiology of this condition. This information could be used in the future to develop diagnostic tests to prevent canine JGD.

Defense Logistics Agency Disposition Services Afghanistan Disposal Process Needed Improvement

DTIC Science & Technology

2013-11-08

audit, and management was proactive in correcting the deficiencies we identified. DLA DS eliminated backlogs, identified and corrected system ...problems, provided additional system training, corrected coding errors, added personnel to key positions, addressed scale issues, submitted debit...Service Automated Information System to the Reutilization Business Integration2 (RBI) solution. The implementation of RBI in Afghanistan occurred in

A Comparison of Alternative Methods of Obtaining Defense Logistics Agency (DLA) Cognizance Spare Parts for Contractor Furnished Equipment (CFE) during Initial Outfitting of New Construction U.S. Navy Ships

DTIC Science & Technology

1991-12-01

database, the Real Time Operation Management Information System (ROMIS), and Fitting Out Management Information System (FOMIS). These three configuration...Codes ROMIS Real Time Operation Management Information System SCLSIS Ship’s Configuration and Logistics Information System SCN Shipbuilding and

Effect of leaf digestion and artemisinin solubility for use in oral consumption of dried Artemisia annua leaves to treat malaria.

PubMed

Desrosiers, Matthew R; Weathers, Pamela J

2016-08-22

Artemisia annua L. produces the antimalarial sesquiterpene lactone, artemisinin (AN), and was traditionally used by the Chinese to treat fever, which was often caused by malaria. To measure effects of plant-based and dietary components on release of artemisinin and flavonoids from A. annua dried leaves (DLA) after simulated digestion. Simulated digestion was performed on DLA in four types of capsules, or in conjunction with protein, and protein-based foods: dry milk, casein, bovine serum albumin, peanuts, peanut butter, Plumpy'nut(®), and A. annua essential oils. Artemisinin and total flavonoids were measured in the liquid phase of the intestinal stage of digestion. After simulated digestion, peanuts and Plumpy'nut(®) lowered AN and flavonoids, respectively, recovered from the liquid digestate fraction. None of the compositions of the tested capsules altered AN or flavonoid release. Surprisingly, bovine serum albumin (BSA) increased both AN and flavonoids recovered from liquid simulated digestate fractions while casein had no effect. AN delivered as DLA was about 4 times more soluble in digestates than AN delivered as pure drug. Addition of a volume of essential oil equivalent to that found in a high essential oil producing A. annua cultivar also significantly increased AN solubility in simulated digestates. These results indicate encapsulating DLA may provide a way to mask the taste of A. annua without altering bioavailability. Similarly, many peanut-based products can be used to mask the flavor with appropriate dosing. Finally, the essential oil fraction of A. annua contributes to the increased AN solubility in DLA after simulated digestion. Our results suggest that use of DLA in the treatment of malaria and other artemisinin-susceptible diseases should be further tested in animals and humans. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs.

PubMed

Friedenberg, Steven G; Buhrman, Greg; Chdid, Lhoucine; Olby, Natasha J; Olivry, Thierry; Guillaumin, Julien; O'Toole, Theresa; Goggs, Robert; Kennedy, Lorna J; Rose, Robert B; Meurs, Kathryn M

2016-03-01

Immune-mediated diseases are common and life-threatening disorders in dogs. Many canine immune-mediated diseases have strong breed predispositions and are believed to be inherited. However, the genetic mutations that cause these diseases are mostly unknown. As many immune-mediated diseases in humans share polymorphisms among a common set of genes, we conducted a candidate gene study of 15 of these genes across four immune-mediated diseases (immune-mediated hemolytic anemia, immune-mediated thrombocytopenia, immune-mediated polyarthritis (IMPA), and atopic dermatitis) in 195 affected and 206 unaffected dogs to assess whether causative or predictive polymorphisms might exist in similar genes in dogs. We demonstrate a strong association (Fisher's exact p = 0.0004 for allelic association, p = 0.0035 for genotypic association) between two polymorphic positions (10 bp apart) in exon 2 of one allele in DLA-79, DLA-79*001:02, and multiple immune-mediated diseases. The frequency of this allele was significantly higher in dogs with immune-mediated disease than in control dogs (0.21 vs. 0.12) and ranged from 0.28 in dogs with IMPA to 0.15 in dogs with atopic dermatitis. This allele has two non-synonymous substitutions (compared with the reference allele, DLA-79*001:01), resulting in F33L and N37D amino acid changes. These mutations occur in the peptide-binding pocket of the protein, and based upon our computational modeling studies, are likely to affect critical interactions with the peptide N-terminus. Further studies are warranted to confirm these findings more broadly and to determine the specific mechanism by which the identified variants alter canine immune system function.

76 FR 21809 - Defense Federal Acquisition Regulation Supplement; Technical Amendments

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-19

... Defense Logistics Agency. [cir] 252.216-7004. Provides needed editorial changes in the clause number in... ``Defense Logistics Agency'' in the definition of ``contracting activity'' to read as follows: 202.101 Definitions. * * * * * Contracting activity * * * Defense Logistics Agency DLA Acquisition (J-7) DLA Aviation...

On the selection of damped Lyman α systems using Mg II absorption at 2 < zabs < 4

NASA Astrophysics Data System (ADS)

Berg, T. A. M.; Ellison, S. L.; Prochaska, J. X.; Sánchez-Ramírez, R.; Lopez, S.; D'Odorico, V.; Becker, G.; Christensen, L.; Cupani, G.; Denney, K.; Worseck, G.

2017-01-01

The XQ-100 survey provides optical and near-infrared coverage of 36 blindly selected, intervening damped Lyman α systems (DLAs) at 2 < zabs < 4, simultaneously covering the Mg II doublet at λλ2796, 2803Å, and the Ly α transition. Using the XQ-100 DLA sample, we investigate the completeness of selecting DLA absorbers based on their Mg II rest-frame equivalent width (W0^{2796}) at these redshifts. Of the 29 DLAs with clean Mg II profiles, we find that six (20 per cent of DLAs) have W0^{2796} < 0.6 Å. The DLA incidence rate of W0^{2796} < 0.6 Å absorbers is a factor of ˜5 higher than what is seen in z ˜ 1 samples, indicating a potential evolution in the Mg II properties of DLAs with redshift. All of the W0^{2796} < 0.6 Å DLAs have low metallicities (-2.5 < [M/H] < -1.7), small velocity widths (v90 < 50 km s-1), and tend to have relatively low N(H I). We demonstrate that the exclusion of these low W0^{2796} DLAs results in a higher mean N(H I) which in turn leads to an ˜7 per cent increase in the cosmological gas density of H I of DLAs at 2 < zabs < 4; and that this exclusion has a minimal effect on the H I-weighted mean metallicity.

32 CFR Appendix B to Part 286 - Addressing FOIA Requests

Code of Federal Regulations, 2012 CFR

2012-07-01

... Administration Under Secretary of Defense (Acquisition & Technology) Deputy Under Secretary of Defense (Logistics... Experiments Command Center On-Site Inspection Agency Under Secretary of Defense (Comptroller) Director..., VA 22314-1651. AP2.2.9. Defense Logistics Agency (DLA). DLA records may be requested from its...

32 CFR Appendix B to Part 286 - Addressing FOIA Requests

Code of Federal Regulations, 2013 CFR

2013-07-01

... Administration Under Secretary of Defense (Acquisition & Technology) Deputy Under Secretary of Defense (Logistics... Experiments Command Center On-Site Inspection Agency Under Secretary of Defense (Comptroller) Director..., VA 22314-1651. AP2.2.9. Defense Logistics Agency (DLA). DLA records may be requested from its...

32 CFR Appendix B to Part 286 - Addressing FOIA Requests

Code of Federal Regulations, 2014 CFR

2014-07-01

... Administration Under Secretary of Defense (Acquisition & Technology) Deputy Under Secretary of Defense (Logistics... Experiments Command Center On-Site Inspection Agency Under Secretary of Defense (Comptroller) Director..., VA 22314-1651. AP2.2.9. Defense Logistics Agency (DLA). DLA records may be requested from its...

32 CFR Appendix B to Part 286 - Addressing FOIA Requests

Code of Federal Regulations, 2011 CFR

2011-07-01

... Administration Under Secretary of Defense (Acquisition & Technology) Deputy Under Secretary of Defense (Logistics... Experiments Command Center On-Site Inspection Agency Under Secretary of Defense (Comptroller) Director..., VA 22314-1651. AP2.2.9. Defense Logistics Agency (DLA). DLA records may be requested from its...

32 CFR 300.2 - DLA FOIA regulatory precedence.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false DLA FOIA regulatory precedence. 300.2 Section 300.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE LOGISTICS AGENCY FREEDOM OF INFORMATION ACT PROGRAM General...

78 FR 17383 - Notice of Availability of Environmental Assessment and Draft Finding of No Significant Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-21

... standard Jet A aviation fuel in most aircraft could significantly reduce fuel transport distances and... Mobility Fuel Purchasing Programs AGENCY: Defense Logistics Agency Energy (DLA Energy), DoD. ACTION... fuel purchase programs. DLA Energy currently operates two programs for mobility fuel contracts, Direct...

32 CFR Appendix A to Part 1285 - Gaining Access to DLA Records

Code of Federal Regulations, 2012 CFR

2012-07-01

... Part 1285 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS DEFENSE LOGISTICS AGENCY FREEDOM OF INFORMATION ACT PROGRAM Pt. 1285, App. A Appendix A to Part 1285—Gaining Access to DLA Records I. General The Defense Logistics Agency was established pursuant to...

32 CFR Appendix A to Part 1285 - Gaining Access to DLA Records

Code of Federal Regulations, 2011 CFR

2011-07-01

... Part 1285 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS DEFENSE LOGISTICS AGENCY FREEDOM OF INFORMATION ACT PROGRAM Pt. 1285, App. A Appendix A to Part 1285—Gaining Access to DLA Records I. General The Defense Logistics Agency was established pursuant to...

32 CFR Appendix A to Part 1285 - Gaining Access to DLA Records

Code of Federal Regulations, 2013 CFR

2013-07-01

... Part 1285 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS DEFENSE LOGISTICS AGENCY FREEDOM OF INFORMATION ACT PROGRAM Pt. 1285, App. A Appendix A to Part 1285—Gaining Access to DLA Records I. General The Defense Logistics Agency was established pursuant to...

48 CFR 204.7204 - Maintenance of the CAGE file.

Code of Federal Regulations, 2014 CFR

2014-10-01

... electronic equivalent, to— DLA Logistics Information Service, DLIS-SBB, Federal Center, 74 Washington Avenue... Maintenance of the CAGE file. (a) DLA Logistics Information Service will accept written requests for changes...) Additional guidance for maintaining CAGE codes is in Volume 7 of DoD 4100.39-M, Federal Logistics Information...

48 CFR 204.7204 - Maintenance of the CAGE file.

Code of Federal Regulations, 2011 CFR

2011-10-01

... electronic equivalent, to— DLA Logistics Information Service, DLIS-SBB, Federal Center, 74 Washington Avenue... Maintenance of the CAGE file. (a) DLA Logistics Information Service will accept written requests for changes...) Additional guidance for maintaining CAGE codes is in Volume 7 of DoD 4100.39-M, Federal Logistics Information...

48 CFR 204.7204 - Maintenance of the CAGE file.

Code of Federal Regulations, 2013 CFR

2013-10-01

... electronic equivalent, to— DLA Logistics Information Service, DLIS-SBB, Federal Center, 74 Washington Avenue... Maintenance of the CAGE file. (a) DLA Logistics Information Service will accept written requests for changes...) Additional guidance for maintaining CAGE codes is in Volume 7 of DoD 4100.39-M, Federal Logistics Information...

48 CFR 204.7204 - Maintenance of the CAGE file.

Code of Federal Regulations, 2012 CFR

2012-10-01

... electronic equivalent, to— DLA Logistics Information Service, DLIS-SBB, Federal Center, 74 Washington Avenue... Maintenance of the CAGE file. (a) DLA Logistics Information Service will accept written requests for changes...) Additional guidance for maintaining CAGE codes is in Volume 7 of DoD 4100.39-M, Federal Logistics Information...

77 FR 16818 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-22

... forms of information technology. DATES: Consideration will be given to all comments received by May 21... Number: 0704-TBD. Needs and Uses: The Application of Child Care Services Form, DLA Form 1854, is used to request child care services provided by DLA managed facilities. Enrollee records are provided to the Child...

32 CFR 1285.5 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS DEFENSE LOGISTICS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 1285.5 Procedures. (a) FOIA channels. If DLA personnel... office, they will immediately forward it to the local FOIA manager. (b) Central log system. Each FOIA...

Paperless Procurement: The Impact of Advanced Automation

DTIC Science & Technology

1992-09-01

System. POPS = Paperless Order Processing System; RADMIS = Research and Development Management Information System; SAACONS=Standard Army Automated... order processing system, which then updates the contractor’s production (or delivery) scheduling and contract accounting applications. In return, the...used by the DLA’s POPS. 3-5 into an EDI delivery order and pass it directly to the distributor’s or manufacturer’s order processing system. That

H2, C I, Metallicity, and Dust Depletion in the Z = 2.34 Damped Lyα Absorption System toward QSO 1232+0815

NASA Astrophysics Data System (ADS)

Ge, Jian; Bechtold, Jill; Kulkarni, Varsha P.

2001-01-01

We report the detection of strong molecular hydrogen (H2) absorption lines in the z=2.34 damped Lyα absorber (DLA) toward QSO 1232+0815. This is the second detection in our survey for high-redshift molecules. The new ultraviolet spectrum of the QSO 1232+0815 at 0.9 Å resolution, taken with the Multiple Mirror Telescope Blue Channel Spectrograph, shows the υ=0-0 up to 10-0 Lyman bands and also the Werner υ=0-0 band of H2 associated with the z=2.34 DLA. We have estimated the total H2 column density in this system. It ranges from ~3×1019 cm-2 to ~3×1017 cm-2 depending on the Doppler parameters, b=6 or 10 km s-1. Based on the best fit with b=6 km s-1, the estimated kinetic temperature is TK~80 K. The measurements of the abundance of zinc and iron in the same DLA show that the metallicity measured by the relatively undepleted element zinc is [Zn/H]=-0.86, while the relative abundance ratio [Fe/Zn] is -1.04, indicating dust depletion. Combining our work with previous results on H2 and relative heavy-element depletion, we find that there is a correlation between them, which suggests that the formation of H2 on dust grains is perhaps the dominant formation process in high-redshift DLAs. Detections of strong absorption from the ground and excited states of neutral carbon (C I) in the z=2.34 DLA are also presented. The excitation temperature between the two fine-structure levels of C I is 15.7+/-3.5 K, an upper limit for the cosmic microwave background radiation temperature at z=2.34. This value is consistent with the prediction by the standard big bang cosmology. Observations here were obtained with the Multiple Mirror Telescope, a joint facility of the University of Arizona and the Smithsonian Institution.

Defense Acquisition Structures and Capabilities Review

DTIC Science & Technology

2007-06-01

systems to joint portfolio management Refinement of a human capital strategy Improvement of governance of the business transformation effort...Management, Senior- Level Tri-Chaired investment panel for the new Concept Decision process for major programs, and Defense Acquisition Executive Summary...establishment of centers of excellence. DLA reorganized to implement the Business Systems Modernization (BSM) initiative designed to improve end-to-end

Two-color hybrid laser wakefield and direct laser accelerator

NASA Astrophysics Data System (ADS)

Zhang, Xi; Khudik, V.; Bernstein, A.; Downer, M.; Shvets, G.

2017-03-01

We propose and investigate the concept of two-color laser wakefield and direct acceleration (LWDA) scheme in the regime of moderate (10 TW scale) laser powers. The concept utilizes two unequal frequency laser pulses: the leading long-wavelength (λ0 = 0.8 µm) wakefield laser pulse driving a nonlinear plasma wake, and a trailing short-wavelength (λDLA = λ0/2) DLA laser pulse. The combination of the large electric field, yet small ponderomotive pressure of the DLA pulse is shown to be advantageous for producing a higher energy and larger charge electron beam compared with the single frequency LWDA. The sensitivity of the dual-frequency LWDA to synchronization time jitter is also reduced.

48 CFR 204.7202-1 - CAGE codes.

Code of Federal Regulations, 2014 CFR

2014-10-01

... issued by DLA Logistics Information Service. (Their address is: Customer Service, Federal Center, 74... Logistics Information Service assigns or records and maintains CAGE codes to identify commercial and... Volume 7 of DoD 4100.39-M, Federal Logistics Information System (FLIS) Procedures Manual, prescribe use...

48 CFR 204.7202-1 - CAGE codes.

Code of Federal Regulations, 2011 CFR

2011-10-01

... issued by DLA Logistics Information Service. (Their address is: Customer Service, Federal Center, 74... Logistics Information Service assigns or records and maintains CAGE codes to identify commercial and... Volume 7 of DoD 4100.39-M, Federal Logistics Information System (FLIS) Procedures Manual, prescribe use...

48 CFR 204.7202-1 - CAGE codes.

Code of Federal Regulations, 2013 CFR

2013-10-01

... issued by DLA Logistics Information Service. (Their address is: Customer Service, Federal Center, 74... Logistics Information Service assigns or records and maintains CAGE codes to identify commercial and... Volume 7 of DoD 4100.39-M, Federal Logistics Information System (FLIS) Procedures Manual, prescribe use...

48 CFR 204.7202-1 - CAGE codes.

Code of Federal Regulations, 2012 CFR

2012-10-01

... issued by DLA Logistics Information Service. (Their address is: Customer Service, Federal Center, 74... Logistics Information Service assigns or records and maintains CAGE codes to identify commercial and... Volume 7 of DoD 4100.39-M, Federal Logistics Information System (FLIS) Procedures Manual, prescribe use...

48 CFR 9.203 - QPL's, QML's, and QBL's.

Code of Federal Regulations, 2010 CFR

2010-10-01

...) Qualification and listing in a QPL, QML, or QBL is the process by which products are obtained from manufacturers... and Standardization Information System (ASSIST) at (http://assist.daps.dla.mil). (c) Instructions concerning qualification procedures are included in the following publications: (1) Federal Standardization...

Focused Logistics: Putting Agility in Agile Logistics

DTIC Science & Technology

2011-05-19

list, ahead of companies like American Express, DuPont and Coca Cola ; Supports nearly 1,900 weapon systems; DLA manages eight supply chains and...35 7) Force Health Protection...Distribution, Information Fusion, Joint Theater Logistics Command and Control, Multinational Logistics, Joint Health Services Support, and Agile

Bias of damped Lyman-α systems from their cross-correlation with CMB lensing

DOE PAGES

Alonso, D.; Colosimo, J.; Font-Ribera, A.; ...

2018-04-20

We cross-correlate the positions of damped Lyman-α systems (DLAs) and their parent quasar catalog with a convergence map derived from the Planck cosmic microwave background (CMB) temperature data. We then make consistent measurements of the lensing signal of both samples in both Fourier and configuration space. By interpreting the excess signal present in the DLA catalog with respect to the parent quasar catalog as caused by the large scale structure traced by DLAs, we are able to infer the bias of these objects: b DLA=2.6±0.9. These results are consistent with previous measurements made in cross-correlation with the Lyman-α forest, althoughmore » the current noise in the lensing data and the low number density of DLAs limits the constraining power of this measurement. We discuss the robustness of the analysis with respect to a number different systematic effects and forecast prospects of carrying out this measurement with data from future experiments.« less

Bias of damped Lyman-α systems from their cross-correlation with CMB lensing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alonso, D.; Colosimo, J.; Font-Ribera, A.

We cross-correlate the positions of damped Lyman-α systems (DLAs) and their parent quasar catalog with a convergence map derived from the Planck cosmic microwave background (CMB) temperature data. We then make consistent measurements of the lensing signal of both samples in both Fourier and configuration space. By interpreting the excess signal present in the DLA catalog with respect to the parent quasar catalog as caused by the large scale structure traced by DLAs, we are able to infer the bias of these objects: b DLA=2.6±0.9. These results are consistent with previous measurements made in cross-correlation with the Lyman-α forest, althoughmore » the current noise in the lensing data and the low number density of DLAs limits the constraining power of this measurement. We discuss the robustness of the analysis with respect to a number different systematic effects and forecast prospects of carrying out this measurement with data from future experiments.« less

Bias of damped Lyman-α systems from their cross-correlation with CMB lensing

NASA Astrophysics Data System (ADS)

Alonso, D.; Colosimo, J.; Font-Ribera, A.; Slosar, A.

2018-04-01

We cross-correlate the positions of damped Lyman-α systems (DLAs) and their parent quasar catalog with a convergence map derived from the Planck cosmic microwave background (CMB) temperature data. We make consistent measurements of the lensing signal of both samples in both Fourier and configuration space. By interpreting the excess signal present in the DLA catalog with respect to the parent quasar catalog as caused by the large scale structure traced by DLAs, we are able to infer the bias of these objects: bDLA=2.6±0.9. These results are consistent with previous measurements made in cross-correlation with the Lyman-α forest, although the current noise in the lensing data and the low number density of DLAs limits the constraining power of this measurement. We discuss the robustness of the analysis with respect to a number different systematic effects and forecast prospects of carrying out this measurement with data from future experiments.

Supply Operations (DLA-O) Total Quality Management (TQM) Master Plan

DTIC Science & Technology

1989-07-01

This document briefly outlines the DLA Directorate of Supply Operations plan to implement total quality management . It seeks to provide better...service to customers at a lower cost through continuous process improvement and commitment from everyone in the organization. Keywords: TQM (total Quality Management ), Supply operations; Continuous process improvement. (KR)

32 CFR Appendix A to Part 300 - Access to DLA Records

Code of Federal Regulations, 2014 CFR

2014-07-01

... OF INFORMATION ACT PROGRAM DEFENSE LOGISTICS AGENCY FREEDOM OF INFORMATION ACT PROGRAM Appendix A to Part 300—Access to DLA Records (a) General. (1) The Defense Logistics Agency, established pursuant to... control of the Assistant Secretary of Defense for Logistics and Materiel Readiness, and is subject to DoD...

75 FR 25844 - Class Deviation From FAR 52.219-7, Notice of Partial Small Business Set-Aside

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-10

... Small Business Set-Aside AGENCY: Defense Logistics Agency, DoD. ACTION: Notice. SUMMARY: This is to...) regarding partial small business set-asides for Defense Logistics Agency (DLA), Defense Energy Support Center (DESC) bulk fuels solicitations and resulting contract awards. DLA is requesting Department of...

From "Sooo Excited!!!" to "So Proud": Using Language to Study Development

ERIC Educational Resources Information Center

Kern, Margaret L.; Eichstaedt, Johannes C.; Schwartz, H. Andrew; Park, Gregory; Ungar, Lyle H.; Stillwell, David J.; Kosinski, Michal; Dziurzynski, Lukasz; Seligman, Martin E. P.

2014-01-01

We introduce a new method, "differential language analysis" (DLA), for studying human development in which computational linguistics are used to analyze the big data available through online social media in light of psychological theory. Our open vocabulary DLA approach finds words, phrases, and topics that distinguish groups of people…

Intracistronic complementation in the simian virus 40 A gene.

PubMed Central

Tornow, J; Cole, C N

1983-01-01

A set of eight simian virus 40 mutants was constructed with lesions in the A gene, which encodes the large tumor (T) antigen. These mutants have small deletions (3-20 base pairs) at either 0.497, 0.288, or 0.243 map units. Mutants having both in-phase and frameshift mutations at each site were isolated. Neither plaque formation nor replication of the mutant DNAs could be detected after transfection of monkey kidney cells. Another nonviable mutant, dlA2459, had a 14-base-pair deletion at 0.193 map unit and was positive for viral DNA replication. Each of the eight mutants were tested for ability to form plaques after cotransfection with dlA2459 DNA. The four mutants that had in-phase deletions were able to complement dlA2459. The other four, which had frameshift deletions, did not. No plaques were formed after cotransfection of cells with any other pair of group A mutants. This suggests that the defect in dlA2459 defines a distinct functional domain of simian virus 40 T antigen. Images PMID:6312452

Artemisia annua dried leaf tablets treated malaria resistant to ACT and i.v. artesunate: Case reports.

PubMed

Daddy, Nsengiyumva Bati; Kalisya, Luc Malemo; Bagire, Pascal Gisenya; Watt, Robert L; Towler, Melissa J; Weathers, Pamela J

2017-08-15

Dried leaf Artemisia annua (DLA) has shown efficacy against Plasmodium sp. in rodent studies and in small clinical trials. Rodent malaria also showed resiliency against the evolution of artemisinin drug resistance. This is a case report of a last resort treatment of patients with severe malaria who were responding neither to artemisinin combination therapy (ACT) nor i.v. artesunate. Of many patients treated with ACTs and i.v. artesunate during the 6 mon study period, 18 did not respond and were subsequently treated with DLA Artemisia annua. Patients were given a dose of 0.5g DLA per os, twice daily for 5d. Total adult delivered dose of artemisinin was 55mg. Dose was reduced for body weight under 30kg. Clinical symptoms, e.g. fever, coma etc., and parasite levels in thick blood smears were tracked. Patients were declared cured and released from hospital when parasites were microscopically undetectable and clinical symptoms fully subsided. All patients were previously treated with Coartem® provided through Santé Rurale (SANRU) and following the regimen prescribed by WHO. Of 18 ACT-resistant severe malaria cases compassionately treated with DLA, all fully recovered. Of the 18, this report details two pediatric cases. Successful treatment of all 18 ACT-resistant cases suggests that DLA should be rapidly incorporated into the antimalarial regimen for Africa and possibly wherever else ACT resistance has emerged. Copyright © 2017. Published by Elsevier GmbH.

Dynamic Loading Assembly for Testing Actuators of Segmented Mirror Telescope

NASA Astrophysics Data System (ADS)

Deshmukh, Prasanna Gajanan; Parihar, Padmakar; Balasubramaniam, Karthik A.; Mishra, Deepta Sundar; Mahesh, P. K.

Upcoming large telescopes are based on Segmented Mirror Telescope (SMT) technology which uses small hexagonal mirror segments placed side by side to form the large monolithic surface. The segments alignment needs to be maintained against external disturbances like wind, gravity, temperature and structural vibration. This is achieved by using three position actuators per segment working at few-nanometer scale range along with a local closed loop controller. The actuator along with a controller is required to meet very stringent performance requirements, such as track rates up to 300nm/s (90mN/s) with tracking errors less than 5nm, dynamical forces of up to ±40N, ability to reject disturbances introduced by the wind as well as by mechanical vibration generated in the mirror cell, etc. To conduct these performance tests in more realistic manner, we have designed and developed a Dynamic Loading Assembly (DLA) at Indian Institute of Astrophysics (IIA), Bangalore. DLA is a computer controlled force-inducing device, designed in a modular fashion to generate different types of user-defined disturbances in extremely precise and controlled manner. Before realizing the device, using a simple spring-mass-damper-based mathematical model, we ensured that the concept would indeed work. Subsequently, simple concept was converted into a detailed mechanical design and parts were manufactured and assembled. DLA has static and dynamic loading capabilities up to 250N and 18N respectively, with a bandwidth sufficient to generate wind disturbances. In this paper, we present various performance requirements of SMT actuators as well as our effort to develop a dynamic loading device which can be used to test these actuators. Well before using DLA for meaningful testing of the actuator, the DLA itself have gone through various tests and improvements phases. We have successfully demonstrated that DLA can be used to check the extreme performance of two different SMT actuators, which are expected to track the position/force with a few nanometer accuracy.

Multiple origins for the DLA at zabs = 0.313 toward PKS 1127-145 indicated by a complex dust depletion pattern of Ca, Ti, and Mn

NASA Astrophysics Data System (ADS)

Guber, C. R.; Richter, P.; Wendt, M.

2018-01-01

Aims: We aim to investigate the dust depletion properties of optically thick gas in and around galaxies and its origin we study in detail the dust depletion patterns of Ti, Mn, and Ca in the multi-component damped Lymanα (DLA) absorber at zabs = 0.313 toward the quasar PKS 1127-145. Methods: We performed a detailed spectral analysis of the absorption profiles of Ca II, Mn II, Ti II, and Na I associated with the DLA toward PKS 1127-145, based on optical high-resolution data obtained with the UVES instrument at the Very Large Telescope. We obtained column densities and Doppler-parameters for the ions listed above and determine their gas-phase abundances, from which we conclude on their dust depletion properties. We compared the Ca and Ti depletion properties of this DLA with that of other DLAs. Results: One of the six analyzed absorption components (component 3) shows a striking underabundance of Ti and Mn in the gas-phase, indicating the effect of dust depletion for these elements and a locally enhanced dust-to-gas ratio. In this DLA and in other similar absorbers, the Mn II abundance follows that of Ti II very closely, implying that both ions are equally sensitive to the dust depletion effects. Conclusions: Our analysis indicates that the DLA toward PKS 1127-145 has multiple origins. With its narrow line width and its strong dust depletion, component 3 points toward the presence of a neutral gas disk from a faint LSB galaxy in front of PKS 1127-145, while the other, more diffuse and dust-poor, absorption components possibly are related to tidal gas features from the interaction between the various, optically confirmed galaxy-group members. In general, the Mn/Ca II ratio in sub-DLAs and DLAs possibly serves as an important indicator to discriminate between dust-rich and dust-poor in neutral gas in and around galaxies.

Metallicity Evolution of Damped Lyα Systems Out to z ~ 5

NASA Astrophysics Data System (ADS)

Rafelski, Marc; Wolfe, Arthur M.; Prochaska, J. Xavier; Neeleman, Marcel; Mendez, Alexander J.

2012-08-01

We present chemical abundance measurements for 47 damped Lyα (DLA) systems, 30 at z > 4, observed with the Echellette Spectrograph and Imager and the High Resolution Echelle Spectrometer on the Keck telescopes. H I column densities of the DLAs are measured with Voigt profile fits to the Lyα profiles, and we find an increased number of false DLA identifications with Sloan Digital Sky Survey at z > 4 due to the increased density of the Lyα forest. Ionic column densities are determined using the apparent optical depth method, and we combine our new metallicity measurements with 195 from previous surveys to determine the evolution of the cosmic metallicity of neutral gas. We find the metallicity of DLAs decreases with increasing redshift, improving the significance of the trend and extending it to higher redshifts, with a linear fit of -0.22 ± 0.03 dex per unit redshift from z = 0.09-5.06. The metallicity "floor" of ≈1/600 solar continues out to z ~ 5, despite our sensitivity for finding DLAs with much lower metallicities. However, this floor is not statistically different from a steep tail to the distribution. We also find that the intrinsic scatter of metallicity among DLAs of ~0.5 dex continues out to z ~ 5. In addition, the metallicity distribution and the α/Fe ratios of z > 2 DLAs are consistent with being drawn from the same parent population with those of halo stars. It is therefore possible that the halo stars in the Milky Way formed out of gas that commonly exhibits DLA absorption at z > 2.

32 CFR Appendix A to Part 1285 - Gaining Access to DLA Records

Code of Federal Regulations, 2010 CFR

2010-07-01

..., medical, chemical, petroleum, industrial, construction, electronics, and general items of supply. The six... aircraft, surface ships, submarines, combat vehicles, and missile systems. b. Defense Electronics Supply... Center, Attn: DCSC-WXA, 3990 E. Broad Street, Columbus, OH 43216-5000. Defense Electronics Supply Center...

32 CFR 634.6 - Requirements for driving privileges.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Section 634.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW... in any state or host country. (2) Comply with laws and regulations governing motor vehicle operations... Vehicle Registration System (VRS). Vehicle registration is required on all Air Force and DLA installations...

32 CFR 634.6 - Requirements for driving privileges.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Section 634.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW... in any state or host country. (2) Comply with laws and regulations governing motor vehicle operations... Vehicle Registration System (VRS). Vehicle registration is required on all Air Force and DLA installations...

32 CFR 634.6 - Requirements for driving privileges.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Section 634.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW... in any state or host country. (2) Comply with laws and regulations governing motor vehicle operations... Vehicle Registration System (VRS). Vehicle registration is required on all Air Force and DLA installations...

32 CFR 634.6 - Requirements for driving privileges.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Section 634.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW... in any state or host country. (2) Comply with laws and regulations governing motor vehicle operations... Vehicle Registration System (VRS). Vehicle registration is required on all Air Force and DLA installations...

78 FR 45182 - Clarification of Sourcing Requirements for the Procurement List

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-26

...) 4140.1-R, DoD Supply Chain Materiel Management Regulation, the AbilityOne Program is designating the... Defense and the General Services Administration Governing Supply Management Relationships Under the National Supply System provides DLA the authority to procure and supply certain assigned products for the...

78 FR 23194 - Federal Acquisition Regulation; Commercial and Government Entity Code

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-18

... Award Management Name Change, Phase 1 Implementation) which will make a global update to all of the... outside the United States; and Support supply chain traceability and integrity efforts. II. Discussion and.... For Contractors registered in the System for Award Management (SAM), the DLA Logistics Information...

77 FR 38036 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-26

... submit to the Office of Management and Budget (OMB) for clearance the following proposal for collection... support from the Federal Reserve Board (FRB) and the Defense Logistics Agency (DLA), the U.S. Census... publishing plants as defined by the North American Industry Classification System (NAICS). It is the only...

78 FR 52511 - Procurement List; Additions and Deletions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-23

..., W7NX USPFO Activity PA ARNG, Annville, PA. Service Type/Location: Integrated Prime Vendor Supply Chain... of PM FSS, does not have a current contract for the provision of Integrated Prime Vendor Supply Chain... kitting or other supply chain management services required were obtained through the DLA depot system. The...

The cosmic evolution of dust-corrected metallicity in the neutral gas

NASA Astrophysics Data System (ADS)

De Cia, Annalisa; Ledoux, Cédric; Petitjean, Patrick; Savaglio, Sandra

2018-04-01

Interpreting abundances of damped Ly-α absorbers (DLAs) from absorption-line spectroscopy has typically been a challenge because of the presence of dust. Nevertheless, because DLAs trace distant gas-rich galaxies regardless of their luminosity, they provide an attractive way of measuring the evolution of the metallicity of the neutral gas with cosmic time. This has been done extensively so far, but typically not taking proper dust corrections into account. The aims of this paper are to: (i) provide a simplified way of calculating dust corrections, based on a single observed [X/Fe], (ii) assess the importance of dust corrections for DLA metallicities and their evolution, and (iii) investigate the cosmic evolution of iron for a large DLA sample. We have derived dust corrections based on the observed [Zn/Fe], [Si/Fe], or [S/Fe], and confirmed their robustness. We present dust-corrected metallicities in a scale of [Fe/H]tot for 236 DLAs over a broad range of z, and assess the extent of dust corrections for different metals at different metallicities. Dust corrections in DLAs are important even for Zn (typically of 0.1-0.2, and up to 0.5 dex), which is often neglected. Finally, we study the evolution of the dust-corrected metallicity with z. The DLA metallicities decrease with redshift, by a factor of 50-100 from today to 12.6 billion years ago (z = 5). When including dust corrections, the average DLA metallicities are 0.4-0.5 dex higher than without corrections. The upper envelope of the relation between metallicity and z reaches solar metallicity at z ≲ 0.5, although some systems can have solar metallicity already out to z 3. Based on observations carried out at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programmes 065.P-0038, 065.O-0063, 066.A-0624, 067.A-0078, and 068.A-0600.

Antiproliferative Activity and Apoptosis Inducing Mechanism of Anthocephalus cadamba on Dalton’s Lymphoma Ascites Cells

PubMed Central

Dolai, Narayan; Islam, Aminul; Haldar, Pallab Kanti

2016-01-01

The purpose of this investigation was to evaluate the antiproliferative and apoptogenic mechanistic studies of methanol extract of Anthocephalus cadamba (MEAC) on Dalton’s lymphoma ascites (DLA) cells treated mice. Determination of antiproliferative activity was performed by using different DLA cells (2×106 cells, i.p.) inoculated mice groups (n = 12). Groups were treated for 14 consecutive days with MEAC at the doses of 200 and 400 mg/Kg b.w. respectively. The mechanism of antiproliferation activity of MEAC was investigated through morphological studies by acridine orange (AO)/ethidium bromide (EB) double staining method. Comet assay was estimated to check the DNA damage induced apoptosis property. Furthermore, flow cytometry (FACS) was used to quantitatively detect the apoptotic rate by double labeling techniques using Annexin-V FITC/propidium iodide staining analysis and apoptotic proteins expression done by western blotting assay method. MEAC exhibited significant (p<0.01) decrease the tumor volume, viable cell count, tumor weight and elevated the life span of DLA tumor bearing mice. Analysis of AO/EB staining and flow cytometry showed that MEAC possessed apoptosis induced antitumor activity on DLA cells in a dose dependant manner. Dose dependent induction of DNA damage on DLA cells were observed after MEAC treatment, which was evident from the appearance of comet tail length. Pro-apoptotic gene, Bax was up-regulated and down-regulation of the Bcl-2/Bax ratio, suggesting that Bcl-2 family involved in the control of apoptosis. Experimental results revealed that MEAC possess potent antitumor activity via induction of cancer cell apoptosis mechanism. PMID:27980586

LogLines. September-October 2009

DTIC Science & Technology

2009-10-01

troop support team jumps on Pacific Partnership bandwagon , supplies aid to mission. Building Blocks 34 Logistics support forms backbone for...floors, pillars and bare walls. A massive sign over the main entrance identifies the location as belonging to DLA. The sign, and the branding of DLA...provide warfighters and other government agencies with comprehensive energy solutions in the most wartime effective and peacetime efficient manner

The Benefits of Recycling Silver - A Precious Metal.

DTIC Science & Technology

1985-09-01

recovery and refinement. Defense Logistics Agency (DLA): Agency responsible for providing, through DLA centers, the most effective and economical support...because of restrictive laws and regulations, mining is either prohibited or economically unfeasible. 5. The stockpile of strategic and critical materials...to maximize recovery efforts. DPDM-R also maintains overall responsibility to conduct the PMRP. The PMRP promotes the economic recovery of precious

Early Fuel Cell Market Deployments: ARRA and Combined (IAA, DLA, ARRA): Quarter 4 2013 Composite Data Products

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurtz, J.; Sprik, S.

2014-06-01

This report includes the composite data products (CDPs) for early fuel cell market deployments in quarter 4 of 2013. Results are presented for ARRA (projects funded by the American Recovery and Reinvestment Act of 2009 [ARRA]) and Combined (projects funded by DOE Interagency Agreements [IAA], Department of Defense Defense Logistics Agency [DLA], and ARRA).

Development of a Dielectric-Loaded Accelerator Test Facility Based on an X-Band Magnicon Amplifier

NASA Astrophysics Data System (ADS)

Gold, S. H.; Kinkead, A. K.; Gai, W.; Power, J. G.; Konecny, R.; Jing, C.; Tantawi, S. G.; Nantista, C. D.; Hu, Y.; Du, X.; Tang, C.; Lin, Y.; Bruce, R. W.; Bruce, R. L.; Fliflet, A. W.; Lewis, D.

2006-01-01

The Naval Research Laboratory (NRL) and Argonne National Laboratory (ANL), in collaboration with the Stanford Linear Accelerator Center (SLAC), are developing a dielectric-loaded accelerator (DLA) test facility powered by the 11.424-GHz magnicon amplifier that was developed jointly by NRL and Omega-P, Inc. Thus far, DLA structures developed by ANL have been tested at the NRL Magnicon Facility without injected electrons, including tests of alumina and magnesium calcium titanate structures at gradients up to ˜8 MV/m. The next step is to inject electrons in order to build a compact DLA test accelerator. The Accelerator Laboratory of Tsinghua University in Beijing, China has developed a 5-MeV electron injector for the accelerator, and SLAC is developing a means to combine the two magnicon output arms, and to drive the injector and an accelerator section with separate control of the power ratio and relative phase. Also, RWBruce Associates, working with NRL, is developing a means to join ceramic tubes to produce long accelerating sections using a microwave brazing process. The installation and commissioning of the first dielectric-loaded test accelerator, including injector, DLA structure, and spectrometer, should take place within the next year.

Immunogenetic aspects of a canine breeding colony.

PubMed

Ladiges, W C; Deeg, H J; Raff, R F; Storb, R

1985-02-01

A colony of dogs was expanded by selective breeding to study the immunogenetic determinants coded for by the major histocompatibility complex (DLA). Polymorphic determinants were identified by alloantisera specific for DLA-A and B loci antigens and by the mixed lymphocyte culture (MLC) which defined alleles at the D locus. Thirteen families totaling 58 offspring were produced and typed for allelic determinants coded for by each of the three gene loci. Allelic segregation in a codominant manner occurred as expected and a recombinant between the A and B loci was detected. A number of animals were homozygous at one or more loci, thus providing genetically standardized animals as a source of typing cells, antigens, and sera to further study the immunogenetic details of DLA and for in vivo studies in transplantation biology.

Witnessing the assembly of galaxies in an extended gas-rich structure at z 3.25

NASA Astrophysics Data System (ADS)

Mackenzie, Ruari

2017-08-01

The direct study of star formation in Damped Lyman Alpha systems (DLAs), the reservoirs of the majority of neutral gas at high redshift, has previously been hampered by the lack of deep integral field spectroscopy for sensitive searches of faint host galaxies. Building on our successful HST shot-in-the-dark survey that has probed the in-situ star formation rate of z 2-3 DLAs, we have initiated a MUSE follow-up of 6 DLA signlines to overcome this bottleneck. In the first sightline we have studied, we have uncovered a 40 kpc Lyman alpha emitting nebula, composed of two clumps within 50 kpc of the DLA, suggestive of a merger or an extended protodisk. Within this structure, which is the largest nebula known to be associated with a z 3 DLA, we also found a compact continuum source with spectrophotometry consistent with a Lyman Break Galaxy at the same redshift. Aside from the LBG, the rest of the Lyman alpha structure has no continuum counterpart in deep UV and visible imaging. The LBG alone seems unable to power the Lyman alpha nebula and the morphology supports our conclusion that, most likely, this structure is powered by in-situ star formation below detection limit. However, from the Lyman alpha alone the origin of this incredible structure remains ambiguous. With this proposal, we aim to acquire high resolution, deep infrared imaging with HST to probe the rest-frame optical emission to search for the underlying stellar emission of this object and to infer the stellar mass of the LBG. With the powerful combination of HST and MUSE data, we will unravel the nature of this unique system.

Loglines. January - February 2011

DTIC Science & Technology

2011-02-01

Curtis’ staff created a snap- shot of DLA’s missions and goals and the agency’s use of its personnel, budget- ary and management resources. Senior...facilities to reduce operating costs while also balancing ef- The second is DoD Warehouse Consolidation, under which DLA would assume management of...Squadron, checks inventory at Scott Air Force Base, Ill. After assuming management of some Navy warehouses, DLA is determining whether efficiencies can

Multiple autoimmune diseases syndrome in Italian Greyhounds: preliminary studies of genome-wide diversity and possible associations within the dog leukocyte antigen (DLA) complex.

PubMed

Pedersen, Niels C; Liu, Hongwei; Greenfield, Daniel L; Echols, Layle Griffioen

2012-01-15

A disorder manifested by multiple autoimmune disorders, and resembling autoimmune polyendocrine syndrome type 2 (APS-2) in humans, may exist in Italian Greyhounds. The incidence of this disorder is increasing and its potential impact on the health of the breed is becoming of great concern. The aims of the present study were to document the existence of this syndrome, conduct a preliminary assessment of genetic diversity across the breed and within affected and unaffected dogs, determine whether the disorder associates with the dog leukocyte antigen (DLA) complex, and demonstrate similarities to APS-2 of humans. To these ends, information on disease, pedigrees, and blood or buccal swab samples were collected from affected and healthy Italian Greyhounds and extracted DNA analyzed. Analysis of Y chromosome markers and mitochondrial DNA sequences showed that Italian Greyhounds evolved from a single patriline and two major and four minor matrilines. A panel of 24 highly polymorphic simple tandem repeat (STR) markers across 20 autosomes demonstrated that affected and unaffected dogs were not distinguishable from the population as a whole by heterozygosity, F-statistics, and principal component analysis (PCA). However, analysis of allele frequencies at each STR loci identified regions of increased or decreased disease risk on four chromosomes. A similar genetic analysis using 109 single nucleotide polymorphisms (SNPs) across the DLA region showed differences between affected and unaffected dogs. PCA and zygosity mapping of DLA SNPs from unrelated dogs demonstrated two distinct subpopulations among the affected individuals. One population was very homozygous and the other closely resembled unaffected dogs in its heterozygosity, suggesting the evolution of a disease prone bloodline as a result of non-random selection. Exon 2 sequencing of the DLA class II genes demonstrated 5-8 alleles at each locus and 14 three loci haplotypes. Two specific haplotypes containing DRB1*00203 or DRB1*02901 were associated with increased disease risk in about one-third of affected dogs. However, high density SNP association mapping across the DLA region and CFA12 did not corroborate the association. Copyright © 2011 Elsevier B.V. All rights reserved.

Evaluation of chromogenic medium and direct latex agglutination test for detection of group B streptococcus in vaginal specimens from pregnant women in Lebanon and Kuwait.

PubMed

Ghaddar, Nahed; Alfouzan, Wadha; Anastasiadis, Elie; Al Jiser, Tamima; Itani, Saad Eddine; Dernaika, Racha; Eid, Toufic; Ghaddar, Ali; Charafeddine, Adib; Dhar, Rita; El Hajj, Hiba

2014-10-01

This study was undertaken to evaluate chromogenic medium and a direct latex agglutination test (DLA) for detection of Group B Streptococcus (GBS) in the vaginal specimens of pregnant women, and to ascertain the prevalence of GBS in this population in Kuwait and Lebanon. Vaginal swabs, collected from women at 35-37 weeks of gestation, were cultured on 5 % sheep blood agar (SBA), colistin nalidixic acid agar (CNA), Strept B Select chromogenic agar (SBS) as well as Lim enrichment broth in 168 cases in Lebanon while only SBA was used for 1391 samples in Kuwait. In addition, vaginal samples from 102 GBS-positive and 20 GBS-negative women near the time of delivery were collected in Kuwait for evaluation of the DLA test. During the study period, the prevalence of GBS colonization was determined to be 20.7 % (288/1391) in Kuwait while 18.4 % (31) of 168 pregnant women in Lebanon had vaginal cultures positive for GBS. By direct plating of vaginal swabs on the three media used, the isolation rates of GBS were 51.6, 64.5 and 77.4 % on SBA, CNA and SBS, respectively, which increased to 90.35, 93.1 and 96.8 %, respectively, following subculture in Lim broth after 18 h of incubation. The sensitivity of the DLA test was found to be dependent on the density of GBS colonization, resulting in 100 % sensitivity and 100 % specificity for heavy (>10(2) c.f.u. per swab) and moderately heavy (50-100 c.f.u. per swab) growth of GBS. However, for vaginal specimens yielding <50 c.f.u. per swab, the sensitivity, specificity, positive and negative predictive values of the DLA test were 100, 55.5, 63.6 and 100 %, respectively. In conclusion, a chromogenic agar, such as SBS, and a DLA test can be used for rapid detection of GBS in pregnant women. The DLA test, in particular, could prove to be a useful tool for immediate detection of GBS in women near delivery so that intrapartum antibiotic prophylaxis can be initiated. © 2014 The Authors.

Association between anal sac gland carcinoma and dog leukocyte antigen-DQB1 in the English Cocker Spaniel.

PubMed

Aguirre-Hernández, J; Polton, G; Kennedy, L J; Sargan, D R

2010-12-01

Anal sac gland carcinomas occur frequently in English Cocker Spaniels and, to a lesser extent, in other spaniel breeds. The disease typically presents in dogs aged 8 years or older and frequently metastasises to the local lymph nodes. The association between anal sac gland carcinoma in English Cocker Spaniels and the major histocompatibility complex class II loci (the dog leukocyte antigen loci DLA-DRB1, -DQA1, -DQB1) was investigated in 42 cases and 75 controls. Based on a corrected error rate of 0.017 for each test, the allele distribution in DLA-DRB1 showed no significant difference between cases and controls (P value = 0.019), while a significant difference was obtained for DLA-DQA1 and -DQB1 alleles (P values are 0.010 and 3.3 × 10⁻⁵). The DLA-DQB1*00701 allele was the most common in both cases and controls, but it had a higher frequency among the former (0.89) than in the latter (0.61), while the second most common allele had a higher frequency in the controls (0.23) than in the cases (0.07). Haplotype distributions were also significantly different between the two groups (P value = 1.61 × 10⁻⁴). This is the second disease in English Cocker Spaniels for which the most common DLA-DQB1 allele in the breed has been shown to have a higher frequency in cases than controls, while the second most common allele in the breed (*02001) has a significantly higher frequency in the controls, compared with the cases. © 2010 John Wiley & Sons A/S.

Canine DLA diversity: 3. Disease studies.

PubMed

Kennedy, L J; Barnes, A; Short, A; Brown, J J; Seddon, J; Fleeman, L; Brkljacic, M; Happ, G M; Catchpole, B; Ollier, W E R

2007-04-01

There are many millions of dogs worldwide, and these dogs have many different functions. The most obvious use is providing companionship, but there are also many working dogs, including guide dogs for the blind, hearing dogs, guard dogs and farm dogs, to mention a few. The health and welfare of these dogs is of great concern to dog owners, dog breeders and to those who use dogs in their work. Dogs spontaneously develop many diseases that are very similar to their human counterparts. Dogs may, therefore, provide exceptional animal models for such diseases. Identifying genetic markers in the dog may be easier than in humans, and may then provide useful information about genes that can be transferred to humans. This study looked for associations between DLA and two autoimmune diseases of the dog, diabetes and hypothyroidism. DLA associations were found for both of these diseases.

Loglines. November-December 2014

DTIC Science & Technology

2014-12-01

of Energy to our list of energy customers . And today, we store Department of Looking back over the past three years, I marvel at the colossal...supporting our host nation’s economies, something I know our customers appreciate. commands serve to remind us why DLA I’m very proud to wrap up my...worldwide and industry customers of DLA. Contents Defense or the Defense Logistics Agency. LOGLINES Official Flagship Publication of the Defense

The Total Quality Management Implementation Plan of the DLA Office of Comptroller

DTIC Science & Technology

1989-06-01

throughout the private and public sectors . Since embracing the concept in March 1988, the Office of the Secretary of Defense has directed all Defense...those in the Military Departments and private sector . The establishment of the DLA Finance Center in Columbus, Ohio, will promote standardization of...process and customer. o Worksite amenities and Quality of Worklife elements. o Adoption of incentive programs under which employees share the

Loglines. July - August 2010

DTIC Science & Technology

2010-08-01

that particular activity or not. assist this effort. We are DLA will help we work toward creating a single-agency environment , we will also build a...24 helps services test renewable fuels. We are DLA 30 single-agency environment , create a sense of community among global workforce...lock? And for a basic light double switch? Do they want steel or The pricing and quality of each justify costs. Product safety is also considered

Stable trichimerism after marrow grafting from 2 DLA-identical canine donors and nonmyeloablative conditioning

PubMed Central

Hogan, William; Kuhr, Christian S.; Diaconescu, Razvan; Harkey, Michael A.; Georges, George E.; Sale, George E.; Zellmer, Eustacia; Baran, Szczepan; Jochum, Christoph; Stone, Brad; Storb, Rainer

2007-01-01

Although hematopoietic cell transplantation (HCT) is generally accomplished using a single donor, multiple donors have been used to enhance the speed of engraftment, particularly in the case of umbilical cord blood grafts. Here we posed the question in the canine HCT model whether stable dual-donor chimerism could be established using 2 DLA-identical donors. We identified 8 DLA-identical littermate triplets in which the marrow recipients received 2 Gy total body irradiation followed by marrow infusions from 2 donors and postgrafting immunosuppression. All 8 dogs showed initial “trichimerism,” which was sustained in 5 dogs, while 2 dogs rejected one of the allografts and remained mixed chimeras, and 1 dog rejected both allografts. Immune function in one trichimeric dog, as tested by mixed leukocyte culture response and antibody response to sheep red blood cells, was found to be normal. Five dogs received kidney grafts from one of their respective marrow donors at least 6 months after HCT without immunosuppressive drugs, and grafts in 4 dogs are surviving without rejection. In summary, following nonmyeloablative conditioning, simultaneous administration of marrow grafts from 2 DLA-identical littermates could result in sustained trichimerism, and immunologic tolerance could include a kidney graft from one of the marrow donors. PMID:17369487

Demonstration of Heavy Hybrid Diesel Fleet Vehicles

DTIC Science & Technology

2016-03-01

Truck, Earth Auger/Digger Derrick 154 Hybrid Electric System Truck, Refuse 54 Hybrid Launch Assist Truck, Dump 921 Truck, Refrigerator 147 Truck, High...Hybrid Electric System Dump Truck 776 Naval Construction Force Truck 1,500 Engineer Tractor 2,942 Heavy Equipment Transporter (HET) 1,961...both trucks using Defense Logistics Agency (DLA) fuel management data. Card readers capture this data at the point of fueling using a specified card

USAF Logistics Process Optimization Study for the Aircraft Asset Sustainment Process. Volume 1.

DTIC Science & Technology

1998-12-31

solely to have a record that could be matched with the CMOS receipt data. (This problem is caused by DLA systems that currently do not populate CMOS with...unable to obtain passwords to the Depot D035 systems. Figure 16 shows daily savings as of 30 September 1998 (current time frame ) and projects savings...Engineering, modeling, and systems/software development company LAN Local Area Network LFA Large Frame Aircraft LMA Logistics Management Agency LMR

32 CFR Appendix A to Part 323 - Instructions for Preparation of System Notices

Code of Federal Regulations, 2011 CFR

2011-07-01

... DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM Pt. 323, App. A Appendix A to... Copies may be obtained from the Defense Logistics Agency, ATTN: DSS-CV, 8725 John J. Kingman Road, Suite... Secretary of Defense has issued DoD Directive 5105.22 (32 CFR part 398), Defense Logistics Agency (DLA), the...

32 CFR Appendix A to Part 323 - Instructions for Preparation of System Notices

Code of Federal Regulations, 2012 CFR

2012-07-01

... DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM Pt. 323, App. A Appendix A to... Copies may be obtained from the Defense Logistics Agency, ATTN: DSS-CV, 8725 John J. Kingman Road, Suite... Secretary of Defense has issued DoD Directive 5105.22 (32 CFR part 398), Defense Logistics Agency (DLA), the...

32 CFR Appendix A to Part 323 - Instructions for Preparation of System Notices

Code of Federal Regulations, 2010 CFR

2010-07-01

... DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM Pt. 323, App. A Appendix A to... Copies may be obtained from the Defense Logistics Agency, ATTN: DSS-CV, 8725 John J. Kingman Road, Suite... Secretary of Defense has issued DoD Directive 5105.22 (32 CFR part 398), Defense Logistics Agency (DLA), the...

40 CFR 57.405 - Formulation, approval, and implementation of requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... study shall be submitted after the end of the worst case three-month period as a part of the next semi... study demonstrating that the SCS will prevent violations of the NAAQS in the smelter's DLA at all times. The reliability study shall include a comprehensive analysis of the system's operation during one or...

Employment Changes Resulting from the Award of Contracts in Labor Surplus Areas,

DTIC Science & Technology

Until 1981, the Department of Defense (DoD), as a result of amendments to their annual Appropriations Acts (known as the Maybank Amendment), had been...coalition of Northeast and Midwest Congressmen succeeded in having the Defense Logistics Agency (DLA) test a modification to the Maybank Amendment and...due to the DLA Maybank Test, the U.S. Army Corps of Engineers Construction Engineering Research Laboratory developed a computer-assisted regional

Defense AT&L (Volume 36, Number 3, May-June 2007)

DTIC Science & Technology

2007-06-01

following five years. What are some of the biggest challenges you’ve dealt with? Photographs by SGT André Reynolds, USA A The biggest challenge is how...director of logistics operations (right); and Lt. Col. Robert Harney, DDAA commander (left). Photograph courtesy Anniston Army Depot Public Affairs Office...better A member of the DLA Contingency Support Team in Afghanistan checks an incoming subsistence shipment.DLA photograph Defense AT&L: May-June 2007 20

Defense Inventory: DOD Needs Additional Information for Managing War Reserve Levels of Meals Ready to Eat

DTIC Science & Technology

2015-05-01

to provide operational ration manufacturers with two types of machines to assist with the cooking and filling and sealing process for operational...and (3) any strategies DLA pursues to balance cost with readiness in supplying WRM. GAO obtained information from the services on their processes ...for identifying WRM requirements, reviewed DLA’s inventory-management processes and related guidance, and interviewed DLA and military service

Loglines. July-August 2011

DTIC Science & Technology

2011-08-01

chain framework and can fill in the gaps for timely delivery to warfighters in the field. To fill its customer requirements, USAMMC-SWA uses the...said. ADO is a Web-based ordering service run by DLA Troop Support. DLA partnered with the Army to develop ADO to replace uniforms for Soldiers...Major Otis Cuffee, DLA’s command senior enlisted leader, discussed the ADO program with other senior Army enlisted leaders. He said he got a lot of

Demonstration of Heavy Hybrid Diesel Fleet Vehicles Final Report Version 2

DTIC Science & Technology

2016-03-29

Rescue 215 Truck, Earth Auger/Digger Derrick 154 Hybrid Electric System Truck, Refuse 54 Hybrid Launch Assist Truck, Dump 921 Truck, Refrigerator...5,013 In-Progress; Hybrid Electric System Dump Truck 776 Naval Construction Force Truck 1,500 Engineer Tractor 2,942 Heavy Equipment Transporter...fuel consumed by both trucks using Defense Logistics Agency (DLA) fuel management data. Card readers capture this data at the point of fueling using a

DLA Class II Alleles and Haplotypes Are Associated with Risk for and Protection from Chronic Hepatitis in the English Springer Spaniel

PubMed Central

Bexfield, Nicholas H.; Watson, Penny J.; Aguirre-Hernandez, Jesús; Sargan, David R.; Tiley, Laurence; Heeney, Jonathan L.; Kennedy, Lorna J.

2012-01-01

Chronic hepatitis (CH) is common in dogs in the United Kingdom. An increased prevalence of the disease is seen in the English Springer spaniel (ESS), and this breed suffer from a severe form with young to middle aged female dogs being predisposed. The disease shares histological features with those of human viral hepatitis, although the specific aetiological agent has not yet been identified. The aim of the current study was to investigate whether dog leucocyte antigen (DLA) class II alleles and haplotypes are associated with susceptibility/resistance to CH in the ESS. Sequence-based genotyping of the polymorphic exon 2 from DLA-DRB1, -DQA1 and -DQB1 class II loci were performed in 66 ESSs with CH and 84 healthy controls. There was a significant difference in the distribution of the protective alleles DRB1*00501 (3.0% vs. 12.0%, odds ratio [OR] = 0.23, 95% confidence interval [CI] = 0.06–0.74) and DQB1*00501 (3.8% vs. 12.0%, OR = 0.29, 95% CI = 0.09–0.85) between cases and controls. The haplotype DLA-DRB1*00501/DQA1*00301/DQB1*00501 was present in 11.9% of controls and 3.0% of cases and was significantly associated with protection against disease development (OR = 0.26, 95% CI = 0.08–0.80). There was a significant difference in the distribution of the risk alleles DRB1*00601 (14.4% vs. 6.5%, OR = 2.40, 95% CI = 1.10–5.63) and DQB1*00701 (14.4% vs. 6.5%, OR = 2.40, 95% CI = 1.10–5.63) between cases and controls. A risk haplotype (DLA-DRB1*00601/DQA1*005011/DQB1*00701) was present in 14.4% of cases and 6.5% of controls and conferred an elevated risk of developing CH with an OR of 3.13 (95% CI = 1.20–8.26). These results demonstrate that DLA class II is significantly associated with risk and protection from developing CH in ESSs. PMID:22870335

Infusion of New Technology into the QML System

NASA Technical Reports Server (NTRS)

Agarwal, Shri

2012-01-01

QML stands for the Qualified Manufacturer List. It is maintained by DLA-Land and Maritime (formerly known as the Defense Supply Center Columbus, DSCC). This talk will address how we are bringing new technology products into the QML system. The focus will be on microcircuit parts used in space application. A new effort championed by NASA will be described. NASA EEE Parts Assurance Group (NEPAG) is making every effort to strengthen the MIL system and thereby support the space flight projects

Total Quality Management, DLA Finance Center

DTIC Science & Technology

1989-07-01

ton. DC 20503. DATE 3. REPORT TYPE AND DATES COVERED SJuly 1989 4. TITLE AND SUBTIT’LE 5. FUNDING NUMBERS Total Quality Management , DLA Finance Center 6...1989 ~ D 14. SUBJECT TERMS 15. NUMBER OF PAGES TQM (Total Quality Management ), Continuous Process Improvement. ., I Management 16. PRICE CODE 17...CONCEPTS TQM BASICS Total Quality Management (TQM) is a concept which is based on the work of a variety of people in a variety of fields. It includes

Loglines. November-December 2013

DTIC Science & Technology

2013-12-01

old furniture , and that’s exactly where all my office furniture came from – DLA Disposition Services. And while that may not be “big money,” it’s...activities worldwide and industry customers of DLA. Contents of this publication are not necessarily the official views of, or endorsed by, the U.S...of guaranteed product that will be purchased under a contract. In the fuel industry , if you can shave a penny or two off per gallon, you can claim

Development of a 20 MeV Dielectric-Loaded Test Accelerator

NASA Astrophysics Data System (ADS)

Gold, Steven H.; Kinkead, Allen K.; Gai, Wei; Power, John G.; Konecny, Richard; Jing, Chunguang; Long, Jidong; Tantawi, Sami G.; Nantista, Christopher D.; Bruce, Ralph W.; Fliflet, Arne W.; Lombardi, Marcie; Lewis, David

2006-11-01

This paper presents a progress report on a joint project by the Naval Research Laboratory (NRL) and Argonne National Laboratory (ANL), in collaboration with the Stanford Linear Accelerator Center (SLAC), to develop a dielectric-loaded test accelerator in the magnicon facility at NRL. The accelerator will be powered by an experimental 11.424-GHz magnicon amplifier that presently produces 25 MW of output power in a ˜250-ns pulse at up to 10 Hz. The accelerator will include a 5-MeV electron injector originally developed at the Tsinghua University in Beijing, China, and can incorporate DLA structures up to 0.5 m in length. The DLA structures are being developed by ANL, and shorter test structures fabricated from a variety of dielectric materials have undergone testing at NRL at gradients up to ˜8 MV/m. SLAC has developed components to distribute the power from the two magnicon output arms to the injector and to the DLA accelerating structure with separate control of the power ratio and relative phase. RWBruce Associates, Inc., working with NRL, has investigated means to join short ceramic sections into a continuous accelerator tube by a brazing process using an intense 83-GHz beam. The installation and testing of the first dielectric-loaded test accelerator, including injector, DLA test structure, and spectrometer, should take place within the next year.

Ganoderma lucidum total triterpenes attenuate DLA induced ascites and EAC induced solid tumours in Swiss albino mice.

PubMed

Smina, T P; Mathew, J; Janardhanan, K K

2016-04-30

G. lucidum total triterpenes were assessed for its apoptosis-inducing and anti-tumour activities. The ability of the total triterpenes to induce apoptosis was evaluated in Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines. Total triterpenes were found to be highly cytotoxic to DLA and EAC cell lines with IC50 values 5 ± 0.32 and 7.9 ± 0.2 µg/ml respectively. Total triterpenes induced apoptosis in both cell lines which is evident from the DNA fragmentation assay. Anti-tumour activity was accessed using DLA induced solid and EAC induced ascites tumour models in Swiss albino mice. Administration of 10, 50 and 100 mg/kg b. wt. total triterpenes showed 11.86, 27.27 and 40.57% increase in life span of animals in ascites tumour model. Treatment with 10, 50 and 100 mg/kg b. wt. total triterpenes exhibited 76.86, 85.01 and 91.03% inhibition in tumour volume and 67.96, 72.38 and 77.90% inhibition in tumour weight respectively in the solid tumour model. The study reveals the significant dose-dependent anti-tumour activity of total triterpenes in both models. Total triterpenes were more active against the solid tumour than the ascites tumour. The anti-oxidant potential and ability to induce cell-specific apoptosis could be contributing to its anti-tumour activities.

Direct fermentation of Jerusalem artichoke tuber powder for production of l-lactic acid and d-lactic acid by metabolically engineered Kluyveromyces marxianus.

PubMed

Bae, Jung-Hoon; Kim, Hyun-Jin; Kim, Mi-Jin; Sung, Bong Hyun; Jeon, Jae-Heung; Kim, Hyun-Soon; Jin, Yong-Su; Kweon, Dae-Hyuk; Sohn, Jung-Hoon

2018-01-20

An efficient production system for optically pure l- and d-lactic acid (LA) from Jerusalem artichoke tuber powder (JAP) was developed by metabolic engineering of Kluyveromyces marxianus. To construct LA-producing strains, the ethanol fermentation pathway of K. marxianus was redirected to LA production by disruption of KmPDC1 and expression of l- and d-lactate dehydrogenase (LDH) genes derived from Lactobacillus plantarum under the control of the K. marxianus translation elongation factor 1α promoter. To further increase the LA titer, the l-LA and d-LA consumption pathway of host strains was blocked by deletion of the oxidative LDH genes KmCYB2 and KmDLD1. The recombinant strains produced 130g/L l-LA and 122g/L d-LA by direct fermentation from 230g/L JAP containing 140g/L inulin, without pretreatment or nutrient supplementation. The conversion efficiency and optical purity were ≫>95% and ≫>99%, respectively. This system using JAP and the inulin-assimilating yeast K. marxianus could lead to a cost-effective process for the production of LA. Copyright © 2017 Elsevier B.V. All rights reserved.

Strategic Distribution Platform Support of CONUS Army Units

DTIC Science & Technology

2011-01-01

agreed to the goal that the SDP will be the source for 85 percent of customer demands stocked in DLA depots. • Leverage high fill rates via scheduled...goal that the SDP will be the source for 85 percent of customer demands stocked in DLA depots (called the “facing fill” or “gross fill rate” metric...RWT metric does not include time spent in backorder status (i.e., no stock was available to ship). 6 The increase in 2003 and into 2004 in the figure

Ontic Engineering and Manufacturing Overcharged the Defense Logistics Agency for Sole Source Spare Parts (REDACTED)

DTIC Science & Technology

2014-09-15

Motor3 ~ Total Markup 1 For 20 of the 21 parts, Ontic’s contract unit prices to DLA included royalty fees . Ontic’s contract unit price to DLA for...the Refrigeration Heat Interchanger part did not include royalty fees . 2 Minor inconsistencies in the percent differences may occur due to rounding...historical price analysis for fluid filter covers and alternating current motors was not sufficient to identifyOntic’s overcharges of royalty fees . Ontic’s

Dollar Summary of Federal Supply Classification and Service Category by Company, FY84, Part 2 (2620-4540).

DTIC Science & Technology

1984-01-01

MANUFACTURING OHIO DLA POWER AND HAND PUMPS 31 COCA - COLA COMPANY INC THE WISCONSIN NAVY POWER AND HAND PUMPS 85 COLE-PARMER INSTRUMENT CO ILLINOIS NAVY...ELECTRICAL & ULTRASONIC EROSION MACHINES 123 OL MARKETING INC OKLAHOMA USAF ELECTRICAL 8 ULTRASONIC EROSION MACHINES 120 JCK & CASTER CO MINNESOTA DLA...FITTINGS FOR ROPE CABLE AND CHAIN ’I9 EILO MANUFACTURING INC OKLAHOMA NAVY FITTINGS FOR ROPE CABLE AND CHAIN !2? GATEWAY MARKETING CORPORATION NEW

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jin Fengtao; Yuan Jianmin

The experimental transmission spectrum of a hot bromine plasma [J. E. Bailey et al., J. Quant. Spectrosc. Radiat. Transf. 81, 31 (2003)] has been simulated by using a detailed level accounting model (DLA). With assumption of the local thermodynamic equilibrium, the major absorption lines of the experimental spectrum are well reproduced by the present DLA calculation, and the details of the absorption line shapes are used to determine the temperature of the plasma. In contrast to the results of two former statistical models, where the temperature was determined via a global fitting to the experimental data, the present DLA diagnosesmore » the plasma temperature by the line ratios of different charge states in the 2p{yields}3d transition groups resulting in a temperature of 37 eV. It is shown that a change of 1 eV in temperature could cause perceptible changes in the simulated spectrum. It is also shown that the 2p{sub 1/2}{yields}3d{sub 3/2} absorptions have been overestimated by the statistical models.« less

Fractal patterns formed by growth of radial viscous fingers*

NASA Astrophysics Data System (ADS)

Praud, Olivier

2004-03-01

We examine fractal patterns formed by the injection of air into oil in a thin (0.13 mm) layer contained between two cylindrical glass plates of 288 mm diameter (a Hele-Shaw cell) [1]. The resultant radially grown patterns are similar to those formed in Diffusion Limited Aggregation (DLA), but the relation between the continuum limit of DLA and continuum (Laplacian) growth remains an open question. Our viscous fingering patterns in the limit of very high pressure difference reach an asymptotic state in which they exhibit a fractal dimension of 1.70± 0.02, in good agreement with a calculation of the fractal dimension of a DLA cluster, 1.713± 0.003 [2]. The generalized dimensions are also computed and show that the observed pattern is self-similar with Dq = 1.70 for all q. Further, the probability density function of shielding angles suggests the existence of a critical angle close to 75 degrees. This result is in accord with numerical and analytical evidence of a critical angle in DLA [3]. Thus fractal viscous fingering patterns and Diffusion Limited Aggregation clusters have a similar geometrical structure. *Work conducted in collaboration with H.L. Swinney, M.G. Moore and Eran Sharon [1] E. Sharon, M. G. Moore, W. D. McCormick, and H. L. Swinney, Phys. Rev. Lett. 91, 205504 (2003). [2] B.Davidovitch et A. Levermann and I. Procaccia, Phys. Rev. E 62, 5919 (2000). [3] D. A. Kessler et al., Phys. Rev. E 57, 6913 (1998).

Adoptive immunotherapy against allogeneic kidney grafts in dogs with stable hematopoietic trichimerism.

PubMed

Graves, Scott S; Hogan, William J; Kuhr, Christian; Diaconescu, Razvan; Harkey, Michael; Sale, George E; Stone, Brad; Georges, George E; Storb, Rainer

2008-11-01

Dogs given nonmyeloablative conditioning and marrow grafts from 2 dog leukocyte antigen (DLA)-identical littermate donors developed stable trichimerism and stably accepted a subsequent kidney graft from one of the marrow donors without the need for immunosuppression. In this study, we used trichimeras to evaluate strategies for adoptive immunotherapy to solid tumors, using the kidney as a tumor surrogate. Three DLA-identical trichimeric recipients were established by simultaneously infusing marrow from 2 DLA-identical donor dogs into a DLA-identical recipient conditioned with 2 Gy of total body irradiation (TBI) and given a short course of postgraft immunosuppression. After stable hematopoietic engraftment was confirmed, a kidney was transplanted from 1 of the 2 marrow donors into each respective trichimeric recipient. Peripheral blood lymphocytes from each kidney donor were then used to sensitize the alternate marrow donor. The trichimeric recipients were given donor lymphocyte infusions (DLIs) from the sensitized dogs and monitored for chimerism, graft-versus-host disease (GVHD), and kidney rejection. After DLI, we observed both prompt rejection of the transplanted marrow and donor kidney and disappearance of corresponding hematopoietic chimerism. Presumably due to shared minor histocompatibility antigens, host chimerism also disappeared, and GVHD in skin, gut, and liver developed. The native kidneys, although exhibiting lymphocytic infiltration, remained functionally normal. This study demonstrates that under certain experimental conditions, the kidney--an organ ordinarily not involved in graft-versus-host reactions--can be targeted by sensitized donor lymphocytes.

Adoptive Immunotherapy against Allogeneic Kidney Grafts in Dogs with Stable Hematopoietic Trichimerism

PubMed Central

Graves, Scott S.; Hogan, William J.; Kuhr, Christian; Diaconescu, Razvan; Harkey, Michael; Sale, George E.; Stone, Brad; Georges, George E.; Storb, Rainer

2008-01-01

Dogs given nonmyeloablative conditioning and marrow grafts from two dog leukocyte antigen- (DLA) identical littermate donors developed stable trichimerism and stably accepted a subsequent kidney graft from one of the marrow donors without the need for immunosuppression. Here, we used trichimeras to evaluate strategies of adoptive immunotherapy to solid tumors, using the kidney as a tumor surrogate. Three DLA-identical trichimeric recipients were established by simultaneously infusing marrow from two DLA-identical donor dogs into a DLA-identical recipient conditioned with 2 Gy total body irradiation and given a short course of postgrafting immunosuppression. After confirming stable hematopoietic engraftment, a kidney was transplanted from one of the two marrow donors into each respective trichimeric recipient. Peripheral blood lymphocytes (PBL) from each kidney donor were then used to sensitize the alternate marrow donor. Donor lymphocyte infusions (DLI) from the sensitized dogs were given to the trichimeric recipients, whereupon chimerism, graft-versus-host disease (GvHD), and kidney rejection were monitored. After DLI, we observed both prompt rejection of the transplanted marrow-donor kidney and disappearance of corresponding hematopoietic chimerism. Presumably, owing to shared minor histocompatibility antigens, host chimerism also disappeared and GvHD in skin, gut, and liver developed. The native kidneys, while showing lymphocytic infiltration, remained functionally normal. The current study demonstrated that under certain experimental conditions, the kidney, an organ ordinarily not involved in graft-versus-host reactions, can be targeted by sensitized donor lymphocytes. PMID:18940673

Measuring distributed leadership agency in a hospital context.

PubMed

Jønsson, Thomas; Unterrainer, Christine; Jeppesen, Hans-Jeppe; Jain, Ajay Kumar

2016-09-19

Purpose The purpose of this paper is to develop and validate an instrument that can measure distributed leadership (DL) as employees' active participation in DL tasks. The authors designate this as the distributed leadership agency (DLA). Design/methodology/approach Data were collected throughout all departments and occupational groups at a merged centralized hospital setting in Denmark. A total of 1,774 employees from 24 hospital departments and 16 occupational groups completed our survey. Structural equation model and confirmatory factor analyses were applied to identify appropriate items and a test for measurement invariance, predictive, discriminant and convergent validity, and ANOVAs were applied to analyse group differences in DLA. Findings The identified unidimensional questionnaire consists of seven items, as it is different from, but associated with, empowering leadership, organizational influence, attitude to participation and trust in management. As theoretically predicted, DLA is positively related to self-efficacy, job satisfaction and innovative behaviour. Chief physicians, permanent employees and employee representatives scored higher on the scale than the rest of their respective counterparts. Practical implications The survey offers a method to assess a distribution of leadership agency in hospital organizations. Such assessment may provide a basis for organizational and leadership development. Originality/value The present study provides a reliable and valid quantitative instrument that measures how much employees at all hierarchical levels are involved in concrete leadership activities in the hospital context. Taking a normative perspective the authors could show that DL - measured with the DLA-questionnaire - has positive effects on employees' behaviour.

U.S. Navy Advanced Receiving: A Better Approach to the Basics.

DTIC Science & Technology

1987-04-01

the Navy and DLA should begin now to plan for electronic interchange of data between their inventory management systems. This would eliminate the...labor savings from work simplification, improved material handling, and better work load planning 0 Material savings from reduced packaging and use of... planning purposes, source distribution managers use the following equa- tion to determine maximum consolidation time: Maximum consolidation time = 21

Compendium of Operations Research and Economic Analysis Studies.

DTIC Science & Technology

1988-09-01

Project 6034 ) 88-19. Enhanced DLA Distribution System (EDDS) - "Pooling" (June 1988) This study looked at the "pooling" concept as proposed under the EIDDS...1-3., Mi3 1 1 ionl. 81-19. LLt Warenousia, tiju Stkrj’.te t\\UL~jidJ’L ytot!ai .ca Analysis (mady 1961) *This r elpr L dOUCctIens anl UCOnIO:li

Molecular hydrogen absorption systems in Sloan Digital Sky Survey

NASA Astrophysics Data System (ADS)

Balashev, S. A.; Klimenko, V. V.; Ivanchik, A. V.; Varshalovich, D. A.; Petitjean, P.; Noterdaeme, P.

2014-05-01

We present a systematic search for molecular hydrogen absorption systems at high redshift in quasar spectra from the Sloan Digital Sky Survey (SDSS)-II Data Release 7 and SDSS-III Data Release 9. We have selected candidates using a modified profile fitting technique taking into account that the Lyα forest can effectively mimic H2 absorption systems at the resolution of SDSS data. To estimate the confidence level of the detections, we use two methods: a Monte Carlo sampling and an analysis of control samples. The analysis of control samples allows us to define regions of the spectral quality parameter space where H2 absorption systems can be confidently identified. We find that H2 absorption systems with column densities log NH2 > 19 can be detected in only less than 3 per cent of SDSS quasar spectra. We estimate the upper limit on the detection rate of saturated H2 absorption systems (NH2 > 19) in damped Lyα (DLA) systems to be about 7 per cent. We provide a sample of 23 confident H2 absorption system candidates that would be interesting to follow up with high-resolution spectrographs. There is a 1σ r - i colour excess and non-significant AV extinction excess in quasar spectra with an H2 candidate compared to standard DLA-bearing quasar spectra. The equivalent widths of C II, Si II and Al III (but not Fe II) absorptions associated with H2 candidate DLAs are larger compared to standard DLAs. This is probably related to a larger spread in velocity of the absorption lines in the H2-bearing sample.

Enterprise Resource Planning Systems Schedule Delays and Reengineering Weaknesses Increase Risks to DoD’s Auditability Goals

DTIC Science & Technology

2012-07-13

completed through SAP -standard templates that are then used for gap analysis as compared to the commercial-off-the-shelf “To-Be” process. The Navy ERP ...13F25-04 4800 Mark Center Drive Alexandria, VA 22350-1500 Acronyms and Abbreviations BPR CMO DAI DCMO DEAMS DLA EBS EC ERP FIAR GAO...overall objective was to evaluate six Enterprise Resource Planning ( ERP ) systems that we identified as necessary for DoD to produce auditable

Manufacturing Technology for Apparel Automation. Phase 1, 2 and 3 Activity.

DTIC Science & Technology

1987-10-15

A189 129 MANUFACTURING TECHNOLOGY FOR APPAREL AUTOMATION PHASE I t/l 2 AND I ACTIVITY(U) NORTH CAROLINA STATE UNIV ATRALEIGH SCHOOL OF TEXTILES E M...34III 1.8 - iai T ON HART St 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 MTC FILE coax Report: NCSU/DLA-87/2 CDRL A004 MANUFACTURING TECHNOLOGY FOR APPAREL...I Report: NCSU/DLA-87/2 CDRL A004 MANUFACTURING TECHNOLOGY FOR APPAREL AUTOMATION Phase I, II and III Activity Edwin M. McPherson North Carolina

Latent heat induced rotation limited aggregation in 2D ice nanocrystals.

PubMed

Bampoulis, Pantelis; Siekman, Martin H; Kooij, E Stefan; Lohse, Detlef; Zandvliet, Harold J W; Poelsema, Bene

2015-07-21

The basic science responsible for the fascinating shapes of ice crystals and snowflakes is still not understood. Insufficient knowledge of the interaction potentials and the lack of relevant experimental access to the growth process are to blame for this failure. Here, we study the growth of fractal nanostructures in a two-dimensional (2D) system, intercalated between mica and graphene. Based on our scanning tunneling spectroscopy data, we provide compelling evidence that these fractals are 2D ice. They grow while they are in material contact with the atmosphere at 20 °C and without significant thermal contact to the ambient. The growth is studied in situ, in real time and space at the nanoscale. We find that the growing 2D ice nanocrystals assume a fractal shape, which is conventionally attributed to Diffusion Limited Aggregation (DLA). However, DLA requires a low mass density mother phase, in contrast to the actual currently present high mass density mother phase. Latent heat effects and consequent transport of heat and molecules are found to be key ingredients for understanding the evolution of the snow (ice) flakes. We conclude that not the local availability of water molecules (DLA), but rather them having the locally required orientation is the key factor for incorporation into the 2D ice nanocrystal. In combination with the transport of latent heat, we attribute the evolution of fractal 2D ice nanocrystals to local temperature dependent rotation limited aggregation. The ice growth occurs under extreme supersaturation, i.e., the conditions closely resemble the natural ones for the growth of complex 2D snow (ice) flakes and we consider our findings crucial for solving the "perennial" snow (ice) flake enigma.

Latent heat induced rotation limited aggregation in 2D ice nanocrystals

NASA Astrophysics Data System (ADS)

Bampoulis, Pantelis; Siekman, Martin H.; Kooij, E. Stefan; Lohse, Detlef; Zandvliet, Harold J. W.; Poelsema, Bene

2015-07-01

The basic science responsible for the fascinating shapes of ice crystals and snowflakes is still not understood. Insufficient knowledge of the interaction potentials and the lack of relevant experimental access to the growth process are to blame for this failure. Here, we study the growth of fractal nanostructures in a two-dimensional (2D) system, intercalated between mica and graphene. Based on our scanning tunneling spectroscopy data, we provide compelling evidence that these fractals are 2D ice. They grow while they are in material contact with the atmosphere at 20 °C and without significant thermal contact to the ambient. The growth is studied in situ, in real time and space at the nanoscale. We find that the growing 2D ice nanocrystals assume a fractal shape, which is conventionally attributed to Diffusion Limited Aggregation (DLA). However, DLA requires a low mass density mother phase, in contrast to the actual currently present high mass density mother phase. Latent heat effects and consequent transport of heat and molecules are found to be key ingredients for understanding the evolution of the snow (ice) flakes. We conclude that not the local availability of water molecules (DLA), but rather them having the locally required orientation is the key factor for incorporation into the 2D ice nanocrystal. In combination with the transport of latent heat, we attribute the evolution of fractal 2D ice nanocrystals to local temperature dependent rotation limited aggregation. The ice growth occurs under extreme supersaturation, i.e., the conditions closely resemble the natural ones for the growth of complex 2D snow (ice) flakes and we consider our findings crucial for solving the "perennial" snow (ice) flake enigma.

The effect of genetic bottlenecks and inbreeding on the incidence of two major autoimmune diseases in standard poodles, sebaceous adenitis and Addison's disease.

PubMed

Pedersen, Niels C; Brucker, Lynn; Tessier, Natalie Green; Liu, Hongwei; Penedo, Maria Cecilia T; Hughes, Shayne; Oberbauer, Anita; Sacks, Ben

2015-01-01

Sebaceous adenitis (SA) and Addison's disease (AD) increased rapidly in incidence among Standard Poodles after the mid-twentieth century. Previous attempts to identify specific genetic causes using genome wide association studies and interrogation of the dog leukocyte antigen (DLA) region have been non-productive. However, such studies led us to hypothesize that positive selection for desired phenotypic traits that arose in the mid-twentieth century led to intense inbreeding and the inadvertent amplification of AD and SA associated traits. This hypothesis was tested with genetic studies of 761 Standard, Miniature, and Miniature/Standard Poodle crosses from the USA, Canada and Europe, coupled with extensive pedigree analysis of thousands more dogs. Genome-wide diversity across the world-wide population was measured using a panel of 33 short tandem repeat (STR) loci. Allele frequency data were also used to determine the internal relatedness of individual dogs within the population as a whole. Assays based on linkage between STR genomic loci and DLA genes were used to identify class I and II haplotypes and disease associations. Genetic diversity statistics based on genomic STR markers indicated that Standard Poodles from North America and Europe were closely related and reasonably diverse across the breed. However, genetic diversity statistics, internal relatedness, principal coordinate analysis, and DLA haplotype frequencies showed a marked imbalance with 30 % of the diversity in 70 % of the dogs. Standard Poodles with SA and AD were strongly linked to this inbred population, with dogs suffering with SA being the most inbred. No single strong association was found between STR defined DLA class I or II haplotypes and SA or AD in the breed as a whole, although certain haplotypes present in a minority of the population appeared to confer moderate degrees of risk or protection against either or both diseases. Dogs possessing minor DLA class I haplotypes were half as likely to develop SA or AD as dogs with common haplotypes. Miniature/Standard Poodle crosses being used for outcrossing were more genetically diverse than Standard Poodles and genetically distinguishable across the genome and in the DLA class I and II region. Ancestral genetic polymorphisms responsible for SA and AD entered Standard Poodles through separate lineages, AD earlier and SA later, and were increasingly fixed by a period of close linebreeding that was related to popular bloodlines from the mid-twentieth century. This event has become known as the midcentury bottleneck or MCB. Sustained positive selection resulted in a marked imbalance in genetic diversity across the genome and in the DLA class I and II region. Both SA and AD were concentrated among the most inbred dogs, with genetic outliers being relatively disease free. No specific genetic markers other than those reflecting the degree of inbreeding were consistently associated with either disease. Standard Poodles as a whole remain genetically diverse, but steps should be taken to rebalance diversity using genetic outliers and if necessary, outcrosses to phenotypically similar but genetically distinct breeds.

Dog leukocyte antigen class II-associated genetic risk testing for immune disorders of dogs: simplified approaches using Pug dog necrotizing meningoencephalitis as a model.

PubMed

Pedersen, Niels; Liu, Hongwei; Millon, Lee; Greer, Kimberly

2011-01-01

A significantly increased risk for a number of autoimmune and infectious diseases in purebred and mixed-breed dogs has been associated with certain alleles or allele combinations of the dog leukocyte antigen (DLA) class II complex containing the DRB1, DQA1, and DQB1 genes. The exact level of risk depends on the specific disease, the alleles in question, and whether alleles exist in a homozygous or heterozygous state. The gold standard for identifying high-risk alleles and their zygosity has involved direct sequencing of the exon 2 regions of each of the 3 genes. However, sequencing and identification of specific alleles at each of the 3 loci are relatively expensive and sequencing techniques are not ideal for additional parentage or identity determination. However, it is often possible to get the same information from sequencing only 1 gene given the small number of possible alleles at each locus in purebred dogs, extensive homozygosity, and tendency for disease-causing alleles at each of the 3 loci to be strongly linked to each other into haplotypes. Therefore, genetic testing in purebred dogs with immune diseases can be often simplified by sequencing alleles at 1 rather than 3 loci. Further simplification of genetic tests for canine immune diseases can be achieved by the use of alternative genetic markers in the DLA class II region that are also strongly linked with the disease genotype. These markers consist of either simple tandem repeats or single nucleotide polymorphisms that are also in strong linkage with specific DLA class II genotypes and/or haplotypes. The current study uses necrotizing meningoencephalitis of Pug dogs as a paradigm to assess simple alternative genetic tests for disease risk. It was possible to attain identical necrotizing meningoencephalitis risk assessments to 3-locus DLA class II sequencing by sequencing only the DQB1 gene, using 3 DLA class II-linked simple tandem repeat markers, or with a small single nucleotide polymorphism array designed to identify breed-specific DQB1 alleles.

Element Abundances in a Gas-rich Galaxy at z = 5: Clues to the Early Chemical Enrichment of Galaxies

NASA Astrophysics Data System (ADS)

Morrison, Sean; Kulkarni, Varsha P.; Som, Debopam; DeMarcy, Bryan; Quiret, Samuel; Péroux, Celine

2016-10-01

Element abundances in high-redshift quasar absorbers offer excellent probes of the chemical enrichment of distant galaxies, and can constrain models for population III and early population II stars. Recent observations indicate that the sub-damped Lyα (sub-DLA) absorbers are more metal-rich than DLA absorbers at redshifts 0 < z < 3. It has also been suggested that DLA metallicity drops suddenly at z > 4.7. However, only three DLAs at z > 4.5 and no sub-DLAs at z > 3.5 have “dust-free” metallicity measurements of undepleted elements. We report the first quasar sub-DLA metallicity measurement at z > 3.5, from detections of undepleted elements in high-resolution data for a sub-DLA at z = 5.0. We obtain fairly robust abundances of C, O, Si, and Fe, using lines outside the Lyα forest. This absorber is metal-poor, with [O/H] = -2.00 ± 0.12, which is ≳4σ below the level expected from extrapolation of the trend for z < 3.5 sub-DLAs. The C/O ratio is {1.8}-0.3+0.4 times lower than in the Sun. More strikingly, Si/O is {3.2}-0.5+0.6 times lower than in the Sun, whereas Si/Fe is nearly (1.2{}-0.3+0.4 times) solar. This absorber does not display a clear alpha/Fe enhancement. Dust depletion may have removed more Si from the gas phase than is common in the Milky Way interstellar medium, which may be expected if high-redshift supernovae form more silicate-rich dust. C/O and Si/O vary substantially between different velocity components, indicating spatial variations in dust depletion and/or early stellar nucleosynthesis (e.g., population III star initial mass function). The higher velocity gas may trace an outflow enriched by early stars. Based on observations obtained at the W.M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W.M. Keck Foundation.

Spatially resolved emission of a high-redshift DLA galaxy with the Keck/OSIRIS IFU

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jorgenson, Regina A.; Wolfe, Arthur M., E-mail: raj@ifa.hawaii.edu

2014-04-10

We present the first Keck/OSIRIS infrared IFU observations of a high-redshift damped Lyα (DLA) galaxy detected in the line of sight to a background quasar. By utilizing the Laser Guide Star Adaptive Optics to reduce the quasar point-spread function to FWHM ∼ 0.''15, we were able to search for and map the foreground DLA emission free from the quasar contamination. We present maps of the Hα and [O III] λλ5007, 4959 emission of DLA 2222–0946 at a redshift of z ∼ 2.35. From the composite spectrum over the Hα emission region, we measure a star formation rate of 9.5 ±more » 1.0 M {sub ☉} yr{sup –1} and a dynamical mass of M {sub dyn} = 6.1 × 10{sup 9} M {sub ☉}. The average star formation rate surface density is (Σ{sub SFR}) = 0.55 M {sub ☉} yr{sup –1} kpc{sup –2}, with a central peak of 1.7 M {sub ☉} yr{sup –1} kpc{sup –2}. Using the standard Kennicutt-Schmidt relation, this corresponds to a gas mass surface density of Σ{sub gas} = 243 M {sub ☉} pc{sup –2}. Integrating over the size of the galaxy, we find a total gas mass of M {sub gas} = 4.2 × 10{sup 9} M {sub ☉}. We estimate the gas fraction of DLA 2222–0946 to be f {sub gas} ∼ 40%. We detect [N II] λ6583 emission at 3σ significance with a flux corresponding to a metallicity of 75% solar. Comparing this metallicity with that derived from the low-ion absorption gas ∼6 kpc away, ∼30% solar, indicates possible evidence for a metallicity gradient or enriched in/outflow of gas. Kinematically, both Hα and [O III] emission show relatively constant velocity fields over the central galactic region. While we detect some red and blueshifted clumps of emission, they do not correspond with rotational signatures that support an edge-on disk interpretation.« less

Loglines. May-June 2014

DTIC Science & Technology

2014-06-01

houses and operational units to teach tools, systems and techniques to help logisticians learn about the agency. Tools of the Trade 12 DLA produces a...problems often pop up during class discussions and provide him with the best teaching examples. One student at Fort Lee, Va., had an issue...training aids. “The demilitarization course is a immensely important for them, because they learn it in the classroom and then go out and actually

Using Performance Measures to Allocate Consumable Funding

DTIC Science & Technology

2007-06-01

The Air Force is now using the Customer Oriented Leveling Technique (COLT) to determine levels for consumable items at its bases. COLT is an...Overview • COLT is a system to set AF retail stock levels for DLA-managed consumable parts to minimize expected customer wait time (ECWT) • COLT...changed please list both.) Original title on 712 A/B: Using Performance Measures to Allocate Consumable Funding If the title was revised

A new candidate for probing Population III nucleosynthesis with carbon-enhanced damped Lyα systems

NASA Astrophysics Data System (ADS)

Cooke, Ryan; Pettini, Max; Murphy, Michael T.

2012-09-01

We report the identification of a very metal poor damped Lyα system (DLA) at zabs = 3.067 295 that is modestly carbon enhanced, with an iron abundance of ˜1/700 solar ([Fe/H] =-2.84) and [C,O/Fe] ≃ +0.6. Such an abundance pattern is likely to be the result of nucleosynthesis by massive stars. On the basis of 17 metal absorption lines, we derive a 2σ upper limit on the DLA's kinetic temperature of TDLA ≤ 4700 K, which is broadly consistent with the range of spin temperature estimates for DLAs at this redshift and metallicity. While the best-fitting abundance pattern shows the expected hallmarks of Population III nucleosynthesis, models of high-mass Population II stars can match the abundance pattern almost as well. We discuss current limitations in distinguishing between these two scenarios and the marked improvement in identifying the remnants of Population III stars expected from the forthcoming generation of 30-m class telescopes. Based on observations collected at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation.

Representation of time interval entrained by periodic stimuli in the visual thalamus of pigeons

PubMed Central

Wang, Shu-Rong

2017-01-01

Animals use the temporal information from previously experienced periodic events to instruct their future behaviors. The retina and cortex are involved in such behavior, but it remains largely unknown how the thalamus, transferring visual information from the retina to the cortex, processes the periodic temporal patterns. Here we report that the luminance cells in the nucleus dorsolateralis anterior thalami (DLA) of pigeons exhibited oscillatory activities in a temporal pattern identical to the rhythmic luminance changes of repetitive light/dark (LD) stimuli with durations in the seconds-to-minutes range. Particularly, after LD stimulation, the DLA cells retained the entrained oscillatory activities with an interval closely matching the duration of the LD cycle. Furthermore, the post-stimulus oscillatory activities of the DLA cells were sustained without feedback inputs from the pallium (equivalent to the mammalian cortex). Our study suggests that the experience-dependent representation of time interval in the brain might not be confined to the pallial/cortical level, but may occur as early as at the thalamic level. PMID:29284554

DLA based compressed sensing for high resolution MR microscopy of neuronal tissue

NASA Astrophysics Data System (ADS)

Nguyen, Khieu-Van; Li, Jing-Rebecca; Radecki, Guillaume; Ciobanu, Luisa

2015-10-01

In this work we present the implementation of compressed sensing (CS) on a high field preclinical scanner (17.2 T) using an undersampling trajectory based on the diffusion limited aggregation (DLA) random growth model. When applied to a library of images this approach performs better than the traditional undersampling based on the polynomial probability density function. In addition, we show that the method is applicable to imaging live neuronal tissues, allowing significantly shorter acquisition times while maintaining the image quality necessary for identifying the majority of neurons via an automatic cell segmentation algorithm.

An Analysis of the Defense Logistics Agency’s Forward Stocking Initiatives at Albany and Barstow Distribution Depots and the Impact on Logistics Response Time

DTIC Science & Technology

placement of 6,255 line items at these respective locations . Data was able available through DLAs Data Warehouse for both the wholesale and retail mission due...to the Base Realignment and Closure Act of 2005 that forced services with co- located DLA Distribution Centers to transfer the retail mission to DLA...Furthermore, an examination of processes at each of the two Marine Corps Logistics Base locations demonstrates areas where further research and possible benchmarking would be beneficial to the supply chain.

Develop a Business Plan

DTIC Science & Technology

1993-10-01

AD-A274 321 ,’U IflIlllME• U I I DEVELOP A BUSINESS PLAN U FINAL REPORT n A Short Term Research and Development Task Proposed Under DLA900-87-D-0017...DATEU COVERED October 1, 1.993 F inal -10/12./89 Q 6󈧢/93 4. TITLE AND SUBTIILE S. FUNDING NUMBERS "Develop a Business Plan" DLA900-87-D-0017 D00017 I...Z39-16 Z9- 107 DEVELOP A BUSINESS PLAN I EXECUTIVE SUMMARY I Funding for CAR’s activities has come from a variety of sources: federal, state, Clemson

A logNHI = 22.6 Damped Lyα Absorber in a Dark Gamma-Ray Burst: The Environment of GRB 050401

NASA Astrophysics Data System (ADS)

Watson, D.; Fynbo, J. P. U.; Ledoux, C.; Vreeswijk, P.; Hjorth, J.; Smette, A.; Andersen, A. C.; Aoki, K.; Augusteijn, T.; Beardmore, A. P.; Bersier, D.; Castro Cerón, J. M.; D'Avanzo, P.; Diaz-Fraile, D.; Gorosabel, J.; Hirst, P.; Jakobsson, P.; Jensen, B. L.; Kawai, N.; Kosugi, G.; Laursen, P.; Levan, A.; Masegosa, J.; Näränen, J.; Page, K. L.; Pedersen, K.; Pozanenko, A.; Reeves, J. N.; Rumyantsev, V.; Shahbaz, T.; Sharapov, D.; Sollerman, J.; Starling, R. L. C.; Tanvir, N.; Torstensson, K.; Wiersema, K.

2006-12-01

The optical afterglow spectrum of GRB 050401 (at z=2.8992+/-0.0004) shows the presence of a damped Lyα absorber (DLA), with logNHI=22.6+/-0.3. This is the highest column density ever observed in a DLA and is about 5 times larger than the strongest DLA detected so far in any QSO spectrum. From the optical spectrum, we also find a very large Zn column density, implying an abundance of [Zn/H]=-1.0+/-0.4. These large columns are supported by the early X-ray spectrum from Swift XRT, which shows a column density (in excess of Galactic) of logNH=22.21+0.06-0.08 assuming solar abundances (at z=2.9). The comparison of this X-ray column density, which is dominated by absorption due to α-chain elements, and the H I column density derived from the Lyα absorption line allows us to derive a metallicity for the absorbing matter of [α/H]=-0.4+/-0.3. The optical spectrum is reddened and can be well reproduced with a power law with SMC extinction, where AV=0.62+/-0.06. But the total optical extinction can also be constrained independent of the shape of the extinction curve: from the optical to X-ray spectral energy distribution, we find 0.5<~AV<~4.5. However, even this upper limit, independent of the shape of the extinction curve, is still well below the dust column that is inferred from the X-ray column density, i.e., AV=9.1+1.4-1.5. This discrepancy might be explained by a small dust content with high metallicity (low dust-to-metals ratio). ``Gray'' extinction cannot explain the discrepancy, since we are comparing the metallicity to a measurement of the total extinction (without reference to the reddening). Little dust with high metallicity may be produced by sublimation of dust grains or may naturally exist in systems younger than a few hundred megayears. Based in part on observations made at the European Southern Observatory, Paranal, Chile under program 075.D-0270, with the Nordic Optical Telescope, operated on the island of La Palma jointly by Denmark, Finland, Iceland, Norway, and Sweden, in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias, with the Wide Field Camera (WFCAM) on the United Kingdom Infrared Telescope, which is operated by the Joint Astronomy Centre on behalf of the UK Particle Physics and Astronomy Research Council, and on data collected at the Subaru Telescope, which is operated by the National Astronomical Observatory of Japan.

Dollar Summary of Prime Contract Awards by State, Place, and Contractor, FY84, Part 2 (Air Force Academy, Colorado-Zion, Illinois).

DTIC Science & Technology

1984-01-01

THEODORE AND COMPANY 32 32 HOLDING HAROLD R 71 71 INTERACTIVE SYSTEMS CORP 297 297 J & R CONSTRUCTION CO INC 94 94 KETCHUM KONKEL & AUSTIN 10 150 MC...TELECOM INC 510 510 DATA SYSTEMS MARKETING 26 26 DUGGAN PETROLEUM CO INC 3,249 3,249 HONEYWELL INC 3,581 267 2,400 830 INTERACTIVE SYSTEMS CORP 424 424...FORCE DLA OCE ODA SANDERSVILLE PRENTISS DRUG & CHEMICAL CO 89 89 TOTAL - SANDERSVILLE 744 744 SAVANNAH A C S CONSTRUCTION CO MISS 550 550 A J C INTL

DOD Business Systems Modernization: Progress Continues to Be Made in Establishing Corporate Management Controls, but Further Steps are Needed

DTIC Science & Technology

2007-05-01

concepts. Figure 3: Simplified Diagram of DOD’s Business Mission Area Federated Architecture Source: GAO analysis of DOD data. Enterprise Shared Services and...tio ns DLA A rc hi te ct ur es Tr an si tio n P la ns S ys te m s S ol ut io ns Ente prise Shared Services and System Capabiliti DOD BEA and...component business architectures’ alignment with incremental versions of the BEA will be achieved; how shared services will be identified, exposed

X-ray ionization of the intergalactic medium by quasars

NASA Astrophysics Data System (ADS)

Graziani, Luca; Ciardi, B.; Glatzle, M.

2018-06-01

We investigate the impact of quasars on the ionization of the surrounding intergalactic medium (IGM) with the radiative transfer code CRASH4, now accounting for X-rays and secondary electrons. After comparing with analytic solutions, we post-process a cosmic volume (≈1.5 × 104 Mpc3h-3) containing a ULAS J1120+0641-like quasar (QSO) hosted by a 5 × 1011M⊙h-1 dark matter (DM) halo. We find that: (i) the average HII region (R ˜ 3.2 pMpc in a lifetime tf = 107 yrs) is mainly set by UV flux, in agreement with semi-analytic scaling relations; (ii) a largely neutral (xHII < 0.001), warm (T ˜ 103 K) tail extends up to few Mpc beyond the ionization front, as a result of the X-ray flux; (iii) LyC-opaque inhomogeneities induce a line of sight (LOS) scatter in R as high as few physical Mpc, consistent with the DLA scenario proposed to explain the anomalous size of the ULAS J1120+0641 ionized region. On the other hand, with an ionization rate \\dot{N}_{γ ,0} ˜ 10^{57} s-1, the assumed DLA clustering and gas opacity, only one LOS shows an HII region compatible with the observed one. We deduce that either the ionization rate of the QSO is at least one order of magnitude lower or the ULAS J1120+0641 bright phase is shorter than 107 yrs.

Improvement of d-Lactic Acid Production in Saccharomyces cerevisiae Under Acidic Conditions by Evolutionary and Rational Metabolic Engineering.

PubMed

Baek, Seung-Ho; Kwon, Eunice Y; Bae, Sang-Jeong; Cho, Bo-Ram; Kim, Seon-Young; Hahn, Ji-Sook

2017-10-01

Microbial lactic acid (LA) production under acidic fermentation conditions is favorable to reduce the production cost, but circumventing LA toxicity is a major challenge. A d-LA-producing Saccharomyces cerevisiae strain JHY5610 is generated by expressing d-lactate dehydrogenase gene (Lm. ldhA) from Leuconostoc mesenteroides, while deleting genes involved in ethanol production (ADH1, ADH2, ADH3, ADH4, and ADH5), glycerol production (GPD1 and GPD2), and degradation of d-LA (DLD1). Adaptive laboratory evolution of JHY5610 lead to a strain JHY5710 having higher LA tolerance and d-LA-production capability. Genome sequencing of JHY5710 reveal that SUR1 I245S mutation increases LA tolerance and d-LA-production, whereas a loss-of-function mutation of ERF2 only contributes to increasing d-LA production. Introduction of both SUR1 I245S and erf2Δ mutations into JHY5610 largely mimic the d-LA-production capability of JHY5710, suggesting that these two mutations, which could modulate sphingolipid production and protein palmitoylation, are mainly responsible for the improved d-LA production in JHY5710. JHY5710 is further improved by deleting PDC1 encoding pyruvate decarboxylase and additional integration of Lm. ldhA gene. The resulting strain JHY5730 produce up to 82.6 g L -1 of d-LA with a yield of 0.83 g g -1 glucose and a productivity of 1.50 g/(L · h) in fed-batch fermentation at pH 3.5. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Dog leucocyte antigen class II diversity and relationships among indigenous dogs of the island nations of Indonesia (Bali), Australia and New Guinea.

PubMed

Runstadler, J A; Angles, J M; Pedersen, N C

2006-11-01

The genetic polymorphism at the dog leucocyte antigen (DLA) class II loci DQA1, DQB1 and DRB1 was studied in a large genetically diverse population of feral and wild-type dogs from the large island nations of Indonesia (Bali), Australia and New Guinea (Bali street dog, dingo and New Guinea singing dog, respectively). Sequence-based typing (SBT) of the hypervariable region of DLA-DRB1, -DQA1 and -DQB1 alleles was used to determine genetic diversity. No new DQA1 alleles were recognized among the three dog populations, but five novel DLA-DRB1 and 2 novel DLA-DQB1 allele sequences were detected. Additional unknown alleles were postulated to exist in Bali street dogs, as indicated by the large percentage of individuals (15%-33%) that had indeterminate DRB1, DQA1 and DQB1 alleles by SBT. All three groups of dogs possessed alleles that were relatively uncommon in conventional purebreds. The New Guinea singing dog and dingo shared alleles that were not present in the Bali street dogs. These findings suggested that the dingo was more closely related to indigenous dogs from New Guinea. Feral dog populations, in particular large ones such as that of Bali, show genetic diversity that existed prior to phenotypic selection for breeds originating from their respective regions. This diversity needs to be identified and maintained in the face of progressive Westernization. These populations deserve further study as potential model populations for the evolution of major histocompatibility complex alleles, for the study of canine genetic diversity, for the development of dog breeds and for studies on the comigration of ancestral human and dog populations.

DLA based compressed sensing for high resolution MR microscopy of neuronal tissue.

PubMed

Nguyen, Khieu-Van; Li, Jing-Rebecca; Radecki, Guillaume; Ciobanu, Luisa

2015-10-01

In this work we present the implementation of compressed sensing (CS) on a high field preclinical scanner (17.2 T) using an undersampling trajectory based on the diffusion limited aggregation (DLA) random growth model. When applied to a library of images this approach performs better than the traditional undersampling based on the polynomial probability density function. In addition, we show that the method is applicable to imaging live neuronal tissues, allowing significantly shorter acquisition times while maintaining the image quality necessary for identifying the majority of neurons via an automatic cell segmentation algorithm. Copyright © 2015 Elsevier Inc. All rights reserved.

Low Voltage MEMS Digital Loudspeaker Array Based on Thin-film PZT Actuators

NASA Astrophysics Data System (ADS)

Fanget, S.; Casset, F.; Dejaeger, R.; Maire, F.; Desloges, B.; Deutzer, J.; Morisson, R.; Bohard, Y.; Laroche, B.; Escato, J.; Leclere, Q.

This paper reports on the development of a Digital Loudspeaker Array (DLA) solution based on Pb(Zr0.52,Ti0.48)O3 (PZT) thin-film actuated membranes. These membranes called speaklets are arranged in a matrix and operate in a binary manner by emitting short pulses of sound pressure. Using the principle of additivity of pressures in the air, it is possible to reconstruct audible sounds. For the first time, electromechanical and acoustic characterizations are reported on a 256-MEMS-membranes DLA. Sounds audible as far as several meters from the loudspeaker have been generated using low voltage (8 V).

Cloning, expression, purification, and activity assay of proteins related to D-lactic acid formation in Lactobacillus rhamnosus.

PubMed

Wang, Xiuwen; Zheng, Zhaojuan; Dou, Peipei; Qin, Jiayang; Wang, Xiaochen; Ma, Cuiqing; Tang, Hongzhi; Xu, Ping

2010-08-01

Two proteins that might be responsible for D-lactic acid (D-LA) formation were screened from the genome database of Lactobacillus rhamnosus GG. The coding genes of the two proteins in L. rhamnosus CASL, ldhD1 and ldhD2, were cloned and expressed in Escherichia coli Rosetta with an inducible expression vector pETDuet-1 (Novagen, Darmstadt, Germany), respectively. The two purified proteins, LdhD-1 and LdhD-2, migrated as a single protein band separately, both corresponding to an apparent molecular mass between 35 kDa and 45 kDa on sodium dodecyl sulfate polyacrylamide gel electrophoresis. The specific activities of LdhD-1 and LdhD-2 catalyzing pyruvate to LA were 0.02 U/mg and 0.21 U/mg, respectively. The configuration of LA converted from pyruvate was determined using high-performance liquid chromatography equipped with a chiral column. Only D-LA was detected when LdhD-1 and LdhD-2 were tested. In summary, the two proteins cloned and expressed in this study were most probably responsible for D-LA formation during fermentation of L. rhamnosus CASL.

Protective Effect of Zingiber officinale Against Dalton's Lymphoma Ascites Tumour by Regulating Inflammatory Mediator and Cytokines.

PubMed

Rubila, Sundararaj; Ranganathan, Thottiam Vasudevan; Sakthivel, Kunnathur Murugesan

2016-12-01

The aim of the present investigation was to evaluate Zingiber officinale paste against Dalton's lymphoma ascites (DLA)-induced tumours in Swiss albino mice. Experimental animals received Z. officinale paste (low dose 100 mg/kg bw and high dose 500 mg/kg bw) orally for eight alternative days. Treatment with Z. officinale paste showed significant increase in haemoglobin level and decrease in aspartate amino transferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyl transferase (γ-GT) level. Z. officinale paste reduced the inflammatory mediators and cytokine levels, such as inducible nitric oxide (iNOS), tumour necrosis factor level (TNF-α) and interleukin-1β (IL-1β). Treatment with Z. officinale paste also significantly increased the antioxidant enzyme level, such as superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and glutathione transferase (GST), and decreased the lipid peroxidation. Treatment also increased the vitamin C and E levels in treated animals compared with the DLA-bearing host. Histopathological studies also confirmed the protective influence of Z. officinale paste against DLA. The present study suggested that Z. officinale paste could be used as natural spice and a potent antitumour agent.

The Effectiveness of Organic Pollutants Removal in Constructed Wetland with Horizontal Sub-Surface Flow / Efektywność Usuwania Zanieczyszczeń Organicznych W Oczyszczalni Hydrofitowej

NASA Astrophysics Data System (ADS)

Jakubaszek, Anita; Sadecka, Zofia

2015-03-01

This paper presents the results of the research work related to the removal efficiency from wastewater organic pollutants and suspended solids at HSSF (horizontal subsurface flow) constructed wetland. The average effectiveness defined as loss of value COD in wastewater has reached 77%, for BOD5 - 80% and TOC - 82%. The effect of seasonal temperature changes and the period of plant vegetation and rest on the effectiveness of wastewater treatment were also analyzed. The results of the presented research showed a decrease in the efficiency of removing organic pollutants from wastewater and suspended solids in the autumn and winter. During the vegetation the object in Małyszyn has been characterized by the effectiveness of wastewater treatment at the level of 78% for COD, 82% for BOD5, and in the non-vegetation period the effectiveness has decreased up to 75% for COD and 74% for BOD5. During the plants growth the total suspension was removed in 88%, whereas during the plants rest efficiency of removing lowered to 69%. W pracy przedstawiono wyniki badań dotyczące efektywności usuwania ze ścieków zanieczyszczeń organicznych w oczyszczalni hydrofitowej. Średnia skuteczność oczyszczania wyrażona jako obniżenie wartości ChZT w ściekach była na poziomie 77%, dla BZT5 80%, a dla OWO 82%. Analizowano również wpływ sezonowych zmian temperatury oraz okresu wegetacji i spoczynku roślin na skuteczność oczyszczania ścieków. Wyniki badań wykazały obniżenie efektywności usuwania zanieczyszczeń organicznych ze ścieków wyrażonych przez ChZT i BZT5 oraz zawiesiny ogólnej w okresie jesienno-zimowym. W okresie wegetacyjnym obiekt w Małyszynie charakteryzował się efektywnością oczyszczania ścieków na poziomie: 78% dla ChZT, 82% dla BZT5, a w sezonie pozawegetacyjnym skuteczność uległa obniżeniu do 75% w przypadku ChZT oraz 74% dla BZT5. Zawiesina ogólna w okresie wegetacji trzciny usuwana była w 88%, a w okresie powegetacyjnym w 69%.

Analysis and Evaluation of Forecasting Methods and Tools to Predict Future Demand for Secondary Chemical-Biological Configuration Items

DTIC Science & Technology

2013-06-01

quantity, the lead time, the process quality and the number of deliveries (Yang & Pan, 2004). Inventory management systems are classified as either...22202-4302, and to the Office of Management and Budget, Paperwork Reduction Project (0704-0188) Washington DC 20503. 1. AGENCY USE ONLY (Leave blank... managed by the Defense Logistics Agency (DLA), Edgewood Chemical Biological Center (ECBC) must be able to complete reviews of all procurement

FAR 13.5 Acquisition Streamlining: Observations and Recommendations for the Defense Logistics Agency

DTIC Science & Technology

2011-04-01

revenues of nearly $41 billion that would put DLA in the top 60 of the Fortune 500 list, ahead of companies like American Express, DuPont and Coca ... Cola . • Employs about 27,000 civilian and military employees. • Supports nearly 1,900 weapon systems. • Manages eight supply chains and nearly 5...achieving performance objectives. Currently there are no reported efforts to incentivize the use of FAR 13.5. Given congressional sponsorship and

Environmental Assessment KC-46A Depot Maintenance Activation, Tinker Air Force Base, Oklahoma. Volume 1

DTIC Science & Technology

2014-03-01

difficulty in obtaining replacement parts, the Ai r Force has challenges in maintaining tbe KC-135 fleet (USAF 2005). Additionally this fleet has been...aircraft fleet wi ll remain within the Ai r Force inventory. Therefore, only the BNSF Rail Yard and DLA Infill were carried forward for further...surface water from C&D activities. In addition, existing Tinker AFB National Pollutant Discharge Elimination System permit, general permits (multi- sector

Interstellar Gas-phase Element Depletions in the Small Magellanic Cloud: A Guide to Correcting for Dust in QSO Absorption Line Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jenkins, Edward B.; Wallerstein, George, E-mail: ebj@astro.princeton.edu, E-mail: walleg@u.washington.edu

We present data on the gas-phase abundances for 9 different elements in the interstellar medium of the Small Magellanic Cloud (SMC), based on the strengths of ultraviolet absorption features over relevant velocities in the spectra of 18 stars within the SMC. From this information and the total abundances defined by the element fractions in young stars in the SMC, we construct a general interpretation on how these elements condense into solid form onto dust grains. As a group, the elements Si, S, Cr, Fe, Ni, and Zn exhibit depletion sequences similar to those in the local part of our Galaxymore » defined by Jenkins. The elements Mg and Ti deplete less rapidly in the SMC than in the Milky Way, and Mn depletes more rapidly. We speculate that these differences might be explained by the different chemical affinities to different existing grain substrates. For instance, there is evidence that the mass fractions of polycyclic aromatic hydrocarbons in the SMC are significantly lower than those in the Milky Way. We propose that the depletion sequences that we observed for the SMC may provide a better model for interpreting the element abundances in low-metallicity Damped Lyman Alpha (DLA) and sub-DLA absorption systems that are recorded in the spectra of distant quasars and gamma-ray burst afterglows.« less

Measurements of CaII absorption, metals and dust in a sample of z ~= 1 DLAs and subDLAs

NASA Astrophysics Data System (ADS)

Nestor, Daniel B.; Pettini, Max; Hewett, Paul C.; Rao, Sandhya; Wild, Vivienne

2008-11-01

We present observations of CaII, ZnII and CrII absorption lines in 16 damped Lyman alpha (DLA) systems and six subDLAs at redshifts 0.6 < zabs < 1.3, obtained for the dual purposes of (i) clarifying the relationship between DLAs and absorption systems selected from their strong CaII lines, and (ii) increasing the still limited sample of Zn and Cr abundance determinations in this redshift range. We find only partial overlap between current samples of intermediate redshift DLAs (which are drawn from magnitude-limited surveys) and strong CaII absorbers: approximately 25 per cent of known DLAs at these redshifts have an associated CaII λ3935 line with a rest-frame equivalent width greater than 0.35 Å, the threshold of the Sloan Digital Sky Survey sample assembled by Wild and her collaborators. The lack of the strongest CaII systems (with equivalent widths greater than 0.5 Å) is consistent with these authors' conclusion that such absorbers are often missed in current DLA surveys because they redden and dim the light of the background quasi-stellar objects. We rule out the suggestion that strong CaII absorption is associated exclusively with the highest column density DLAs. Furthermore, we find no correlation between the strength of the CaII lines and either the metallicity or degree of depletion of refractory elements, although the strongest CaII absorber in our sample is also the most metal-rich DLA yet discovered, with [Zn/H] ~= solar. We conclude that a complex mix of parameters must determine the strengths of the CaII lines, including the density of particles and ultraviolet photons in the interstellar media of the galaxies hosting the DLAs. We find tentative evidence (given the small size of our sample) that strong CaII systems may preferentially sample regions of high gas density, perhaps akin to the DLAs exhibiting molecular hydrogen absorption at redshifts z > 2. If this connection is confirmed, strong CaII absorbers would trace possibly metal rich, H2 bearing columns of cool, dense gas at distances up to tens of kpc from normal galaxies. Based on the observations made with the William Herschel Telescope operated on the island of La Palma by the Isaac Newton Group in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias. E-mail: dbn@ast.cam.ac.uk

DLA Systems Modernization Methodology: Logical Analysis and Design Procedures

DTIC Science & Technology

1990-07-01

Information Requirement would have little meaning and thus would lose its value . 3 I3 I 1.1.3 INPUT PRODUCTS 3 1.1.3.1 Enterprise Model Objective List 1.1.3.2...at the same time, the attribute is said to be multi- valued . i For example, an E-R model may contain information on the languages an employee speaks...Relationship model is examined in detail to ensure that each data group contains attributes whose values are absolutely determined by their respective

Evaluation of the class II region of the major histocompatibility complex of the greyhound with the genomic matching technique and sequence-based typing.

PubMed

Fliegner, R A; Holloway, S A; Lester, S; McLure, C A; Dawkins, R L

2008-08-01

The class II region of the major histocompatibility complex was evaluated in 25 greyhounds by sequence-based typing and the genomic matching technique (GMT). Two new DLA-DRB1 alleles were identified. Twenty-four dogs carried the DLA-DRB1*01201/DQA1*00401/DQB1*01303/DQB1*01701 haplotype, which carries two DQB1 alleles. One haplotype was identified from which DQB1 and DQA1 appeared to be deleted. The GMT enabled detection of DQB1 copy number, discrimination of the different class II haplotypes and the identification of new, possibly biologically relevant polymorphisms.

The effects of lipid A on gamma-irradiated human peripheral blood lymphocytes in vitro

NASA Astrophysics Data System (ADS)

Dubničková, M.; Kuzmina, E. A.; Chausov, V. N.; Ravnachka, I.; Boreyko, A. V.; Krasavin, E. A.

2016-03-01

The modulatory effects of lipid A (diphosphoryl lipid A (DLA) and monophosphoryl lipid A (MLA)) on apoptosis induction and DNA structure damage (single and double-strand breaks (SSBs and DSBs, respectively)) in peripheral human blood lymphocytes are studied for 60Co gamma-irradiation. It is shown that in the presence of these agents the amount of apoptotic cells increases compared with the irradiated control samples. The effect is most strongly pronounced for DLA. In its presence, a significant increase is observed in the number of radiation-induced DNA SSBs and DSBs. Possible mechanisms are discussed of the modifying influence of the used agents on radiation-induced cell reactions

Synthesis and characterization of near-infrared absorbing water soluble squaraines and study of their photodynamic effects in DLA live cells.

PubMed

Shafeekh, Kulathinte M; Soumya, Mohanannair S; Rahim, Moochikkadavath A; Abraham, Annie; Das, Suresh

2014-01-01

Here, we report the synthesis, photophysical properties and photodynamic effects in DLA live cells of three water soluble squaraine dyes, viz. bisbenzothiazolium squaraine dyes SQMI and SQDI with iodine in one and both benzothiazolium units, respectively, and an unsymmetrical squaraine dye ASQI containing iodinated benzothiazolium and aniline substituents. The diiodinated SQDI showed an anomalous trend in both fluorescence and triplet quantum yields over the monoiodinated SQMI, with SQDI showing higher fluorescence and lower triplet quantum yields compared to SQMI. Nanosecond laser flash photolysis of SQDI and SQMI indicated the formation of triplet excited states with quantum yield of 0.19 and 0.26, respectively. On photoirradiation, both the SQDI and SQMI generate singlet oxygen and it was observed that both dyes undergoing oxidation reactions with the singlet oxygen generated. ASQI which exhibited a lower triplet quantum yield of 0.06 was, however, stable and did not react with the singlet oxygen generated. In vitro cytotoxicity studies of these dyes in DLA live cells were performed using Trypan blue dye exclusion method and it reflect an order of cytotoxicity of SQDI>SQMI>ASQI. Intracellular generation of the ROS was confirmed by dichlorofluorescein assay after the in vitro PDT. © 2014 The American Society of Photobiology.

ALMA + VLT observations of a damped Lyman-α absorbing galaxy: massive, wide CO emission, gas-rich but with very low SFR

NASA Astrophysics Data System (ADS)

Møller, P.; Christensen, L.; Zwaan, M. A.; Kanekar, N.; Prochaska, J. X.; Rhodin, N. H. P.; Dessauges-Zavadsky, M.; Fynbo, J. P. U.; Neeleman, M.; Zafar, T.

2018-03-01

We are undertaking an Atacama Large Millimeter Array survey of molecular gas in galaxies selected for their strong H I absorption, so-called damped Lyα absorber (DLA)/sub-DLA galaxies. Here, we report CO(2-1) detection from a DLA galaxy at z = 0.716. We also present optical and near-infrared (NIR) spectra of the galaxy revealing [O II], Hα, and [N II] emission lines shifted by ˜170 km s-1 relative to the DLA, and providing an oxygen abundance 3.2 times solar, similar to the absorption metallicity. We report low unobscured SFR˜1 M⊙ yr-1 given the large reservoir of molecular gas, and also modest obscured SFR =4.5_{-2.6}^{+4.4} M⊙ yr-1 based on far-IR and sub-millimetre data. We determine mass components of the galaxy: log[M*/M_{&sun} ]= 10.80^{+0.07}_{-0.14}, log[Mmol-gas/M⊙] = 10.37 ± 0.04, and log[Mdust/M_{⊙} ]= 8.45^{+0.10}_{-0.30}. Surprisingly, this H I absorption-selected galaxy has no equivalent objects in CO surveys of flux-selected samples. The galaxy falls off current scaling relations for the star formation rate (SFR) to molecular gas mass and CO Tully-Fisher relation. Detailed comparison of kinematical components of the absorbing, ionized, and molecular gas, combined with their spatial distribution, suggests that part of the CO gas is both kinematically and spatially decoupled from the main galaxy. It is thus possible that a major starburst in the past could explain the wide CO profile as well as the low SFR. Support for this also comes from the spectral energy distribution favouring an instantaneous burst of age ≈0.5 Gyr. Our survey will establish whether flux-selected surveys of molecular gas are missing a key stage in the evolution of galaxies and their conversion of gas to stars.

The Sightline to Q2343-BX415: Clues to Galaxy Formation in a Quasar Environment

NASA Astrophysics Data System (ADS)

Rix, Samantha A.; Pettini, Max; Steidel, Charles C.; Reddy, Naveen A.; Adelberger, Kurt L.; Erb, Dawn K.; Shapley, Alice E.

2007-11-01

We have discovered a strong DLA coincident in redshift with the faint QSO Q2343-BX415 (R=20.2, zem=2.57393). Follow-up observations at intermediate spectral resolution reveal that the metal lines associated with this proximate DLA (PDLA) consist of two sets of absorption components. One set is moving toward the quasar with velocities of ~150-600 km s-1 this gas is highly ionized and does not fully cover the continuum source, suggesting that it is physically close to the active nucleus. The other, which accounts for most of the neutral gas, is blueshifted relative to the QSO, with the strongest component at ~-160 km s-1. We consider the possibility that the PDLA arises in the outflowing interstellar medium of the host galaxy of Q2343-BX415, an interpretation supported by strong C IV and N V absorption at nearby velocities, and by the intense radiation field longward of the Lyman limit implied by the high C II*/H I ratio. If Q2343-BX415 is the main source of these UV photons, then the PDLA is located at either ~8 or ~37 kpc from the active nucleus. Alternatively, the absorber may be a foreground star-forming galaxy unrelated to the quasar and coincidentally at the same redshift, but our deep imaging and follow-up spectroscopy of the field of Q2343-BX415 has not yet produced a likely candidate. We measure the abundances of 14 elements in the PDLA, finding an overall metallicity of ~1/5 solar and a normal pattern of relative element abundances for this metallicity. Thus, in this PDLA there is no evidence for the supersolar metallicities that have been claimed for some proximate, high-ionization, systems. Based on data obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and NASA, and was made possible by the generous financial support of the W. M. Keck Foundation.

Progress in characterizing submonolayer island growth: Capture-zone distributions, growth exponents, & hot precursors

NASA Astrophysics Data System (ADS)

Einstein, Theodore L.; Pimpinelli, Alberto; González, Diego Luis; Morales-Cifuentes, Josue R.

2015-09-01

In studies of epitaxial growth, analysis of the distribution of the areas of capture zones (i.e. proximity polygons or Voronoi tessellations with respect to island centers) is often the best way to extract the critical nucleus size i. For non-random nucleation the normalized areas s of these Voronoi cells are well described by the generalized Wigner distribution (GWD) Pβ(s) = asβ exp(-bs2), particularly in the central region 0.5 < s < 2 where data are least noisy. Extensive Monte Carlo simulations reveal inadequacies of our earlier mean field analysis, suggesting β = i + 2 for diffusion-limited aggregation (DLA). Since simulations generate orders of magnitude more data than experiments, they permit close examination of the tails of the distribution, which differ from the simple GWD form. One refinement is based on a fragmentation model. We also compare island-size distributions. We compare analysis by island-size distribution and by scaling of island density with flux. Modifications appear for attach-limited aggregation (ALA). We focus on the experimental system para-hexaphenyl on amorphous mica, comparing the results of the three analysis techniques and reconciling their results via a novel model of hot precursors based on rate equations, pointing out the existence of intermediate scaling regimes between DLA and ALA.

Microprocessor-controlled iontophoretic drug delivery of 5-fluorouracil: pharmacodynamic and pharmacokinetic study.

PubMed

Chandrashekar, N S; Shobha Rani, R H

2007-01-01

The purpose of this study was to fabricate monolithic 5-fluorouracil (5-FU) transdermal patch with microprocessor- controlled iontophoretic delivery, to evaluate the pharmacodynamic effects on Dalton's lymphoma ascites (DLA) induced in Balb/c mice, and to study pharmacokinetics in rabbits. The transdermal patches were prepared by solvent casting method; a reprogrammable microprocessor was developed and connected to the patches. DLA cells were injected to the hind limb of Balb/c mice (10 animals/group). In the first group of mice 5-FU was administered i.v. (12 mg/kg). In the second group of mice, transdermal patches (20 mg/patch/animal) were installed and kept for 10 consecutive days, while the third (control) group was kept without any treatment. The tumor diameter was measured every 5th day for 30 days, and the animal survival time and death pattern were studied. The electric current density protocol of 0.5 mA/cm(2) for 30 min was used in the pharmacokinetic study in rabbits. There was a significant reduction in tumor volume in the animals treated with monolithic matrix 5-FU transdermal patch compared to untreated controls and i.v. therapy. Tumor volume of the control animals was 5.8 cm(3) on the 30th day, while in 5-FU with transdermal patch delivery animals it was only 0.23 cm(3) (p <0.05). DLA cells tumor-bearing mice treated with 5-FU with transdermal patch had significantly increased lifespan (ILS). Control animals survived only 21+/-1 days after the tumor inoculation, while i.v. 5-FU and 5-FU patches animals survived 24+/-2.7 days and 39.5+/-1.87 days with ILS of 25.58% and 88.09%, respectively (p <0.01). There was significant sustained release of 5-FU through microprocessor-controlled patches and half-life was significantly higher (p <0.05) compared to the i.v. route. Cytotoxic concentration of 5-FU can be achieved through the transdermal drug delivery and effective therapeutic drug concentration can be maintained up to 24 h, with less toxicity. A new generation of transdermal drug delivery systems based on microprocessor-controlled iontophoresis is in the late stages of development and promises to enhance the treatment of local and systemic medical conditions. The incorporation of microprocessor into these systems has been an important advancement to ensure safe and efficient administration of a wide variety of drugs.

Editors pp iii Effects of long-range magnetic interactions on DLA aggregation [rapid communication

NASA Astrophysics Data System (ADS)

Xu, Xiao-Jun; Cai, Ping-Gen; Ye, Quan-Lin; Xia, A.-Gen; Ye, Gao-Xiang

2005-04-01

An extra degree of freedom is introduced in the well-known diffusion-limited aggregation model, i.e., the growth entities are “spin” taking. The model with long-range magnetic interactions that decay as βC/rα on two-dimensional square lattices is studied for different values of α. This model leads to a wide variety of kinetic processes and morphology distribution with both the coupling energy βC and the range of the interactions, i.e., the exponent α. The simulated result of the model shows that the “quenching” of the degree of freedom on the cluster by the long-range magnetic interactions leads to branching or compactness, but, moreover, to combined geometric and physical “transitions” of the aggregations with the growth parameters.

32 CFR 323.2 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.2 Applicability. This part: (a) Applies to Defense Logistics Agency Headquarters (DLA HQ) and all other organizational entities within the Defense Logistics...

32 CFR 323.2 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.2 Applicability. This part: (a) Applies to Defense Logistics Agency Headquarters (DLA HQ) and all other organizational entities within the Defense Logistics...

Particle acceleration on a chip: A laser-driven micro-accelerator for research and industry

NASA Astrophysics Data System (ADS)

Yoder, R. B.; Travish, G.

2013-03-01

Particle accelerators are conventionally built from radio-frequency metal cavities, but this technology limits the maximum energy available and prevents miniaturization. In the past decade, laser-powered acceleration has been intensively studied as an alternative technology promising much higher accelerating fields in a smaller footprint and taking advantage of recent advances in photonics. Among the more promising approaches are those based on dielectric field-shaping structures. These ``dielectric laser accelerators'' (DLAs) scale with the laser wavelength employed and can be many orders of magnitude smaller than conventional accelerators; DLAs may enable the production of high-intensity, ultra-short relativistic electron bunches in a chip-scale device. When combined with a high- Z target or an optical-period undulator, these systems could produce high-brilliance x-rays from a breadbox-sized device having multiple applications in imaging, medicine, and homeland security. In our research program we have developed one such DLA, the Micro-Accelerator Platform (MAP). We describe the fundamental physics, our fabrication and testing program, and experimental results to date, along with future prospects for MAP-based light-sources and some remaining challenges. Supported in part by the Defense Threat Reduction Agency and National Nuclear Security Administration.

Dust and Diffuse Interstellar Bands in the za = 0.524 Absorption System toward AO 0235+164

NASA Astrophysics Data System (ADS)

Junkkarinen, V. T.; Cohen, Ross D.; Beaver, E. A.; Burbidge, E. M.; Lyons, R. W.; Madejski, G.

2004-10-01

We present new Hubble Space Telescope (HST) Space Telescope Imaging Spectrograph (STIS) NUV-MAMA and STIS CCD observations of the BL Lac object AO 0235+164 and the intervening damped Lyα (DLA) line at za=0.524. The line profile gives N(HI)=(5+/-1)×1021 cm-2 and, combined with the H I 21 cm absorption data, leads to a spin temperature of Ts=220+/-60 K. Those spectra also show a strong, broad feature at the expected position of the 2175 Å graphitic dust feature at za=0.524. Assuming a Galactic-type dust extinction curve at za=0.524 gives a dust-to-gas ratio of 0.19 times the Galactic value, but the fit, assuming that the underlying, unreddened spectrum is a single power law, is poor in the far-UV. A dust-to-gas ratio of 0.19 times the Galactic value is similar to the LMC, but the AO 0235+164 spectrum does not fit either the LMC extinction curve or the SMC extinction curve (which has practically no 2175 Å feature). A possible interpretation includes dust similar to that in the Galaxy, but with fewer of the small particles that produce the far-UV extinction. The metallicity of the za=0.524 absorber, estimated from the observed N(HI) and excess X-ray absorption (beyond Galactic) derived from contemporaneous and archival ASCA and ROSAT X-ray data, is Z=0.72+/-0.28 Zsolar, implying in turn a dust-to-metals ratio of 0.27 times the Galactic value. If the dust mass density is the same in the za=0.524 DLA system as in our Galaxy, only 14% (+/-6%) of the metals (by mass) are in dust, compared to 51%, 36%, and 46% for the Galaxy, LMC, and SMC, respectively. Such a dusty za=0.524 AO 0235+164 absorption system is a good example of the kind of DLA system that will be missed because of selection effects, which in turn can bias the measurement of the comoving density of interstellar gas (in units of the closure density), Ωg, as a function of z. Based on observations with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555. Some of the data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation.

Office of Command Security Total Quality Management Plan

DTIC Science & Technology

1989-07-01

outlines the Office of Command Security instruction for TQM implementation. Keywords: TQM (Total Quality Management ), DLA Office of Command Security, Continuous process improvement, Automatic data processing security.

32 CFR 634.48 - General.

Code of Federal Regulations, 2012 CFR

2012-07-01

... DLA in crime prevention, traffic safety, and the orderly flow of vehicle traffic movement. (b) The... INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Impounding Privately Owned Vehicles § 634.48 General. This...

32 CFR 634.48 - General.

Code of Federal Regulations, 2011 CFR

2011-07-01

... DLA in crime prevention, traffic safety, and the orderly flow of vehicle traffic movement. (b) The... INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Impounding Privately Owned Vehicles § 634.48 General. This...

32 CFR 634.48 - General.

Code of Federal Regulations, 2013 CFR

2013-07-01

... DLA in crime prevention, traffic safety, and the orderly flow of vehicle traffic movement. (b) The... INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Impounding Privately Owned Vehicles § 634.48 General. This...

32 CFR 634.48 - General.

Code of Federal Regulations, 2014 CFR

2014-07-01

... DLA in crime prevention, traffic safety, and the orderly flow of vehicle traffic movement. (b) The... INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Impounding Privately Owned Vehicles § 634.48 General. This...

32 CFR 300.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAM DEFENSE LOGISTICS AGENCY FREEDOM OF INFORMATION ACT PROGRAM General Provisions § 300.1 Purpose. This part provides policies and procedures for the Defense Logistics Agency (DLA) implementation of the...

A Systematic Approach for Obtaining Performance on Matrix-Like Operations

NASA Astrophysics Data System (ADS)

Veras, Richard Michael

Scientific Computation provides a critical role in the scientific process because it allows us ask complex queries and test predictions that would otherwise be unfeasible to perform experimentally. Because of its power, Scientific Computing has helped drive advances in many fields ranging from Engineering and Physics to Biology and Sociology to Economics and Drug Development and even to Machine Learning and Artificial Intelligence. Common among these domains is the desire for timely computational results, thus a considerable amount of human expert effort is spent towards obtaining performance for these scientific codes. However, this is no easy task because each of these domains present their own unique set of challenges to software developers, such as domain specific operations, structurally complex data and ever-growing datasets. Compounding these problems are the myriads of constantly changing, complex and unique hardware platforms that an expert must target. Unfortunately, an expert is typically forced to reproduce their effort across multiple problem domains and hardware platforms. In this thesis, we demonstrate the automatic generation of expert level high-performance scientific codes for Dense Linear Algebra (DLA), Structured Mesh (Stencil), Sparse Linear Algebra and Graph Analytic. In particular, this thesis seeks to address the issue of obtaining performance on many complex platforms for a certain class of matrix-like operations that span across many scientific, engineering and social fields. We do this by automating a method used for obtaining high performance in DLA and extending it to structured, sparse and scale-free domains. We argue that it is through the use of the underlying structure found in the data from these domains that enables this process. Thus, obtaining performance for most operations does not occur in isolation of the data being operated on, but instead depends significantly on the structure of the data.

Diamond field emitter array cathodes and possibilities for employing additive manufacturing for dielectric laser accelerating structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simakov, Evgenya Ivanovna; Andrews, Heather Lynn; Herman, Matthew Joseph

2016-09-20

These are slides for a presentation at Stanford University. The outline is as follows: Motivation: customers for compact accelerators, LANL's technologies for laser acceleration, DFEA cathodes, and additive manufacturing of micron-size structures. Among the stated conclusions are the following: preliminary study identified DFEA cathodes as promising sources for DLAs--high beam current and small emittance; additive manufacturing with Nanoscribe Professional GT can produce structures with the right scale features for a DLA operating at micron wavelengths (fabrication tolerances need to be studied, DLAs require new materials). Future plans include DLA experiment with a beam produced by the DFEA cathode with fieldmore » emission, demonstration of photoemission from DFEAs, and new structures to print and test.« less

A search for genetic diversity among Italian Greyhounds from Continental Europe and the USA and the effect of inbreeding on susceptibility to autoimmune disease.

PubMed

Pedersen, Niels C; Liu, Hongwei; Leonard, Angela; Griffioen, Layle

2015-01-01

Previous studies documented the problem of inbreeding among Italian Greyhounds (IG) from the USA and its possible role in a multiple autoimmune disease syndrome. The present study is an extension of these earlier experiments and had two objectives: 1) to identify pockets of additional genetic diversity that might still exist among IG from the USA and Continental Europe, and 2) to determine how loss of genetic diversity within the genome and in the dog leukocyte antigen (DLA) complex relates to the problem of autoimmune disease in IG from the USA. Genetic testing was conducted using 33 short tandem repeat (STR) loci across 25 chromosomes and 7 STR loci that associated with specific dog leukocyte antigen (DLA) class I and II haplotypes. Standard genetic assessment tests based on allele frequencies and internal relatedness (IR) were used as measures of breed-wide and individual heterozygosity. The results of these tests demonstrated that IG from the USA and Continental Europe belonged to a single breed but were genetically distinguishable by genomic allele frequencies, DLA class I and II haplotypes, and principal coordinate analysis (PCoA). In the second part of the study, 85 IG from the USA that had suffered various autoimmune disorders (case) and 104 healthy dogs (control) of comparable age were studied for genetic associations with disease. Case dogs were found to be significantly more homozygous in the DLA regions than control dogs. Principal coordinate analysis did not differentiate case from control populations. No specific STR-associated DLA-class I or II haplotype was associated with increased autoimmune disease risks. Reasons for the loss of genetic diversity and increased homozygosity among IG from the USA were studied using registration data and deep pedigrees. The breed in the USA started from a small number of founders from Europe and has remained relatively isolated and small in numbers, limiting breeding choices especially in the period before modern transportation and artificial insemination. An additional cause of lost diversity and increased homozygosity has been the influence of famous sires and their show-winning progeny. The most influential of these sires was Ch. Dasa's King of the Mountain (King) born in 1978. Virtually all contemporary IG from the USA have King at least once in 10 generation pedigrees and 18 % of the genome of contemporary IG from the USA is shared with King. It was concluded that artificial genetic bottlenecks have concentrated numerous genetic polymorphisms responsible for autoimmune disease and that these risk factors did not originate in a specific individual or bloodline of the breed. Rather, they were of ancestral origin in both purebred and random bred dogs and inherited by descent. Italian Greyhound breeders in the USA have several options to improve breed health: 1) breed against homozygosity within the genome and in the DLA region, 2) avoid breeding dogs that have suffered an autoimmune disorder, 3) increase diversity by incorporating the genetic differences that exist in IG from Continental Europe, or 4) outcross to other small sighthound breeds. The latter two approaches must be undertaken with care to avoid introduction of new deleterious traits and to maximize retention and dissemination of new genetic diversity.

Analysis of The Rayleigh Number in the Area of Steel Rectangular Sections in the Conditions of Stedy and Unstedy Heat Flow/ Analiza Liczby Rayleigha W Obszarze Stalowych Profili Prostokątnych W Warunkach Ustalonego I Nieustalonego Przepływu Ciepła

NASA Astrophysics Data System (ADS)

Wyczółkowski, Rafał

2014-09-01

The paper presents the experimental measurements dedicated to the research for the Rayleigh number (Ra) in the area of rectangular steel sections. This problem is associated with the analysis of the free convection which takes place in the heating of sections bundles during the heat treatment. The study was conducted for both steady and transient heat transfer. The values of the Ra number obtained for the tested sections allow to describe the phenomenon of convection on the basis of a very simple criterial dependence. It greatly simplifies the mathematical description of the heat transfer phenomenon in the concerned charges. W artykule przedstawiono wyniki badań eksperymentalnych, których celem było określonie liczby Rayleigha (Ra) dla profili prostokątnch, nagrzewanych w warunkach ustalonej i nieustalonej wymiany ciepła. Analizie poddano trzy rodzaje profili: 40×20 mm, 60×60 mm oraz 80×80 mm. Badania dla warunków ustalonych przeprowadzono w komorze grzewczej stanowiska do pomiarów efektywnej przewodności cieplnej wsadów porowatych. Natomiast badania w warunkach nieustalonych przeprowadzono w elektrycznym piecu komorowym. Charakter zmian liczby Ra w funkcji temperatury, dla obu sposobów nagrzewania jest podobny. W każdym z przypadków, maksymalną wartość parametr Ra uzyskuje w przedziale temperatury około 100÷200°C. Dla profili 80×80 mm parametr ten jest około sześciokrotnie większy w porównaniu z profilami 60×60 mm. W przypadku nieustalonego przepływu ciepła, bezwzględne wartości parametru Ra są o rząd wielkości większe od wartości uzyskanych dla warunków ustalonych. Odnotowane liczby Ra nie przekroczyły wartości 107. Maksymalna wartość tego parametru wyniosła około 1,2×106. Zatem przy nagrzewaniu analizowanych profili, występujacą w ich wnętrzu konwekcję, można traktować jako intensyfikację przewodzenia w wypełniającym je powietrzu. Wyniki przedstawionych badań posłużą do analizy wpływu występującej wewnątrz profili konwekcji, na proces nagrzewania wiązek tych elementów. Ostatecznym wynikiem prowadzonych w tym zakresie analiz, będzie opracowanie modelu do wyznaczania efektywnej przewodności cieplnej tego wsadu.

Left atrial function in patients with light chain amyloidosis: A transthoracic 3D speckle tracking imaging study.

PubMed

Mohty, Dania; Petitalot, Vincent; Magne, Julien; Fadel, Bahaa M; Boulogne, Cyrille; Rouabhia, Dounia; ElHamel, Chahrazed; Lavergne, David; Damy, Thibaud; Aboyans, Victor; Jaccard, Arnaud

2018-04-01

Systemic light chain amyloidosis (AL) is characterized by the extracellular deposition of amyloid fibrils. Transthoracic echocardiography is the modality of choice to assess cardiac function in patients with AL. Whereas left ventricular (LV) function has been well studied in this patient population, data regarding the value of left atrial (LA) function in AL patients are lacking. In this study, we aim to examine the impact of LA volumes and function on survival in AL patients as assessed by real-time 3D echocardiography. A total of 77 patients (67±10 years, 60% men) with confirmed AL and 39 healthy controls were included. All standard 2D echocardiographic and 3D-LA parameters were obtained. Fourteen patients (18%) were in Mayo Clinic (MC) stage I, 30 (39%) in stage II, and 33 (43%) in stage III at initial evaluation. There was no significant difference among the MC stages groups in terms of age, gender, or cardiovascular risk factors. As compared to patients in MC II and MC I, those in MC III had significantly larger indexed 3D-LA volumes (MCIII: 46±15mL/m 2 , MC II: 38±12mL/m 2 , and MC I: 23±9mL/m 2 , p<0.0001), lower 3D-LA total emptying fraction (3D-tLAEF) (21±13% vs. 31±15% vs. 43±7%, respectively, p<0.0001), and worse 3D peak atrial longitudinal strain (3D-PALS) (11±9% vs. 18±13% vs. 20±7%, respectively, p=0.007). Two-year survival was significantly lower in patients with 3D-tLAEF <+34% (p=0.003) and in those with 3D-PALS <+14% (p=0.034). Both parameters provided incremental prognostic value over maximal LA volume in multivariate analysis. Functional LA parameters are progressively altered in AL patients according to the MC stage. A decrease in 3D-PALS is associated with worse outcome, independently of LA volume. Copyright © 2017 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

DLA Information Systems Technology Integration Guide for the Fiscal Year of 1991

DTIC Science & Technology

1991-01-01

systems which currently exist. In addition, the institution of full and open - opetition for acquisitions for our information systems has driven us...00 U,~c U U C )C/) III 0. -- -------- U)) 0 i U) U)C )z~ w nU U )c < ID a oE co 0 )C c ) 0 cu cuwwwwww Pag E0 I-- I - 0 < 0~0 I- a)) -Jc oo Page...0 -- co Ea -- LL . 0 E c 0) E- I-- w > G, 0 4A 0 .9 Page 1 0u 0 Q. x cts C0 m 0o > n0 ) 0-6 V (t) co .0=)E: Go c ’V x 0- 0 V) E Cc~ E C) ~ < o a

DLA Class II Alleles Are Associated with Risk for Canine Symmetrical Lupoid Onychodystropy (SLO)

PubMed Central

Wilbe, Maria; Ziener, Martine Lund; Aronsson, Anita; Harlos, Charlotte; Sundberg, Katarina; Norberg, Elin; Andersson, Lisa; Lindblad-Toh, Kerstin; Hedhammar, Åke; Andersson, Göran; Lingaas, Frode

2010-01-01

Symmetrical lupoid onychodystrophy (SLO) is an immune-mediated disease in dogs affecting the claws with a suggested autoimmune aethiology. Sequence-based genotyping of the polymorphic exon 2 from DLA-DRB1, -DQA1, and -DQB1 class II loci were performed in a total of 98 SLO Gordon setter cases and 98 healthy controls. A risk haplotype (DRB1*01801/DQA1*00101/DQB1*00802) was present in 53% of cases and 34% of controls and conferred an elevated risk of developing SLO with an odds ratio (OR) of 2.1. When dogs homozygous for the risk haplotype were compared to all dogs not carrying the haplotype the OR was 5.4. However, a stronger protective haplotype (DRB1*02001/DQA1*00401/DQB1*01303, OR = 0.03, 1/OR = 33) was present in 16.8% of controls, but only in a single case (0.5%). The effect of the protective haplotype was clearly stronger than the risk haplotype, since 11.2% of the controls were heterozygous for the risk and protective haplotypes, whereas this combination was absent from cases. When the dogs with the protective haplotype were excluded, an OR of 2.5 was obtained when dogs homozygous for the risk haplotype were compared to those heterozygous for the risk haplotype, suggesting a co-dominant effect of the risk haplotype. In smaller sample sizes of the bearded collie and giant schnauzer breeds we found the same or similar haplotypes, sharing the same DQA1 allele, over-represented among the cases suggesting that the risk is associated primarily with DLA-DQ. We obtained conclusive results that DLA class II is significantly associated with risk of developing SLO in Gordon setters, thus supporting that SLO is an immune-mediated disease. Further studies of SLO in dogs may provide important insight into immune privilege of the nail apparatus and also knowledge about a number of inflammatory disorders of the nail apparatus like lichen planus, psoriasis, alopecia areata and onycholysis. PMID:20808798

DSMC (Defense Systems Management College) CALS (Computer-Aided Acquisition and Logistics Support) Briefing: Program Manager Course.

DTIC Science & Technology

1988-11-01

library . o Air Force Tech Order Management System - Final Report, library o DLA CALS 1988 Implementation Plan, library . Where to go for Additional...0. ~l l LU; 0. 0 0 2. o 3 0 I) 0 U no V) 4- C 4. U) 00 u c.C0 Cco C Cl) cc m~0-CU . d" CD 0 m mooc Er.C 0 .0> s -w 2 c IM CO (aC wi E 0 r. X 0-0 a 0...as well as wider application. The Air Force AFTOMS Automation Plan, a copy of which is in the library , has excellent discussions of the expected

Microwave-assisted extraction with water for fast extraction and simultaneous RP-HPLC determination of phenolic acids in radix Salviae Miltiorrhizae.

PubMed

Fang, Xinsheng; Wang, Jianhua; Zhou, Hongying; Jiang, Xingkai; Zhu, Lixiang; Gao, Xin

2009-07-01

An optimized microwave-assisted extraction method using water (MAE-W) as the extractant and an efficient HPLC analysis method were first developed for the fast extraction and simultaneous determination of D(+)-(3,4-dihydroxyphenyl) lactic acid (Dla), salvianolic acid B (SaB), and lithospermic acid (La) in radix Salviae Miltiorrhizae. The key parameters of MAE-W were optimized. It was found that the degradation of SaB was inhibited when using the optimized MAE-W and the stable content of Dla, La, and SaB in danshen was obtained. Furthermore, compared to the conventional extraction methods, the proposed MAE-W is a more rapid method with higher yield and lower solvent consumption with a reproducibility (RSD <6%). In addition, using water as extractant is safe and helpful for environment protection, which could be referred to as green extraction. The separation and quantitative determination of the three compounds was carried out by a developed reverse-phase high-performance liquid chromatographic (RP-HPLC) method with UV detection. Highly efficient separation was obtained using gradient solvent system. The optimized HPLC analysis method was validated to have specificity, linearity, precision, and accuracy. The results indicated that MAE-W followed by HPLC-UV determination is an appropriate alternative to previously proposed method for quality control of radix Salviae Miltiorrhizae.

48 CFR 8.703 - Procurement list.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Administration (GSA) Supply Catalog and GSA's Customer Service Center Catalogs with a black square and the words “NIB/NISH Mandatory Source,” and in similar catalogs issued by the Defense Logistics Agency (DLA) and...

41 CFR 101-26.600 - Scope and applicability of subpart.

Code of Federal Regulations, 2013 CFR

2013-07-01

... procurement sources of the Department of Defense (DOD), which include the Defense supply centers of the Defense Logistics Agency (DLA) and the inventory control points of the military departments. The...

41 CFR 101-26.600 - Scope and applicability of subpart.

Code of Federal Regulations, 2011 CFR

2011-07-01

... procurement sources of the Department of Defense (DOD), which include the Defense supply centers of the Defense Logistics Agency (DLA) and the inventory control points of the military departments. The...

41 CFR 101-26.600 - Scope and applicability of subpart.

Code of Federal Regulations, 2012 CFR

2012-07-01

... procurement sources of the Department of Defense (DOD), which include the Defense supply centers of the Defense Logistics Agency (DLA) and the inventory control points of the military departments. The...

41 CFR 101-26.600 - Scope and applicability of subpart.

Code of Federal Regulations, 2014 CFR

2014-07-01

... procurement sources of the Department of Defense (DOD), which include the Defense supply centers of the Defense Logistics Agency (DLA) and the inventory control points of the military departments. The...

41 CFR 101-26.600 - Scope and applicability of subpart.

Code of Federal Regulations, 2010 CFR

2010-07-01

... procurement sources of the Department of Defense (DOD), which include the Defense supply centers of the Defense Logistics Agency (DLA) and the inventory control points of the military departments. The...

48 CFR 8.703 - Procurement list.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Administration (GSA) Supply Catalog and GSA's Customer Service Center Catalogs with a black square and the words “NIB/NISH Mandatory Source,” and in similar catalogs issued by the Defense Logistics Agency (DLA) and...

Diamond field emitter array cathodes and possibilities of employing additive manufacturing for dielectric laser accelerating structures

NASA Astrophysics Data System (ADS)

Simakov, Evgenya I.; Andrews, Heather L.; Herman, Matthew J.; Hubbard, Kevin M.; Weis, Eric

2017-03-01

Demonstration of a stand-alone practical dielectric laser accelerator (DLA) requires innovation in two major critical components: high-current ultra-low-emittance cathodes and efficient laser accelerator structures. LANL develops two technologies that in our opinion are applicable to the novel DLA architectures: diamond field emitter array (DFEA) cathodes and additive manufacturing of photonic band-gap (PBG) structures. This paper discusses the results of testing of DFEA cathodes in the field-emission regime and the possibilities for their operation in the photoemission regime, and compares their emission characteristics to the specific needs of DLAs. We also describe recent advances in additive manufacturing of dielectric woodpile structures using a Nanoscribe direct laser-writing device capable of maskless lithography and additive manufacturing, and the development of novel infrared dielectric materials compatible with additive manufacturing.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY83, Part 6 (Johnson Textile & Plastics Co-McKee Robert E Gen Contractor).

DTIC Science & Technology

1983-01-01

M15 0 INC TEXARKANA TEXAS 093818 7840 44 147-83-C0101 D C E 1 2 2 Y129 000 C2 CONSTRUCTION/OTHER AIRFIELD 8 A 3 4 J 018 1 B J 1 1 76 JOWETT INC 147...RENTAL OF EQ/ADP EQUIP 8 A 4 5 J 1013 5 B J 1 I 3u. KETRON INC ION TOTAL 3 825 2 F D2701 1053 N00039-8, 2 D PAlO 1345 N00140- TEXARKANA TEXAS 029859...F4265C KIEBCO FOODS INC 1 4 J 0013H 2017 DLA131 4 J 0013H 2026 DLA13) .1STING OCTOBER - SEPTEMBER FY 83. PAGE 4137 MPC613 ALPHABETIC I I SM 222 V 0

Adoptive immunotherapy against kidney targets in dog-leukocyte antigen-identical mixed hematopoietic canine chimeras.

PubMed

Junghanss, Christian; Takatu, Alessandra; Little, Marie-Terese; Maciej Zaucha, J; Zellmer, Eustacia; Yunusov, Murad; Sale, George; Georges, George E; Storb, Rainer

2003-02-15

Stable mixed-donor-host-hematopoietic chimerism can serve as a platform for adoptive immunotherapy. Infusions of donor lymphocytes (DLI) sensitized against hematopoietic cells converted mixed hematopoietic into full-donor chimerism in dog-leukocyte antigen (DLA)-identical littermates. Whether sensitization against tissue of solid organs leads to organ-specific immunity that can be transferred by DLI was unknown and was investigated in these experiments using the kidney as target. DLA-identical recipients with established stable mixed-donor-host-hematopoietic chimerism were used. In five pairs, hematopoietic stem-cell transplant (HSCT) donors were sensitized by kidney transplantation from the respective chimeras. In a second group, five HSCT donors received vaccinations that were generated from kidney cells of the respective mixed chimeras. Twenty-eight days after sensitization, DLI were administered to the mixed-hematopoietic chimeras. All HSCT donors rejected their kidney grafts from their mixed-chimeric recipients within 22 to 45 days. DLI caused no sustained graft-versus-kidney effects in the mixed-chimeric recipients. However, DLI donors sensitized by kidney transplantation converted 4 of 5 mixed chimeras into virtually complete (>95%) donor-type chimeras, compared with 1 of 5 mixed chimeras given DLI by vaccination from sensitized donors. Although DLA-identical kidney grafts from mixed-hematopoietic chimeras were readily rejected by their HSCT donors, subsequent transfusions of sensitized-donor lymphocytes into mixed chimeras converted mixed to all-donor chimerism but failed to induce graft-versus-kidney effects. Vaccination strategies in lieu of kidney grafts failed to convert mixed chimerism.

Geriatric depression and its relation with cognitive impairment and dementia.

PubMed

Dillon, Carol; Tartaglini, María Florencia; Stefani, Dorina; Salgado, Pablo; Taragano, Fernando E; Allegri, Ricardo F

2014-01-01

Different subtypes of depressive syndromes exist in late life; many of them have cognitive impairment and sometimes it is difficult to differentiate them from dementia. This research aimed to investigate subtypes of geriatric depression associated with cognitive impairment, searched for differential variables and tried to propose a study model. A hundred and eighteen depressive patients and forty normal subjects matched by age and educational level were evaluated with an extensive neuropsychological battery, scales to evaluate neuropsychiatric symptoms and daily life activities (DLA). Depressive patients were classified in groups by SCAN 2.1: Major Depression Disorder (MDD) (n: 31), Dysthymia Disorder (DD) (n: 31), Subsyndromal Depression Disorder (SSD) (n: 29), Depression due to Dementia (n: 27) (DdD). Neuropsychological significant differences (p<0.05) were observed between depressive groups, demonstrating distinctive cognitive profiles. Moreover, significant differences (p<0.05) were found in DLA between DdD vs all groups and MDD vs controls and vs SSD. Age of onset varied in the different subtypes of depression. Beck Depression Inventory (BDI) and Mini Mental State Examination (MMSE) were significant variables that helped to differentiate depressive groups. Significant correlations between BDI and Neuropsychological tests were found in MDD and DD groups. Depressive symptoms and its relation with neuropsychological variables, MMSE, cognitive profiles, DLA and age of onset of depression should be taken into consideration for the study of subtypes of geriatric depression. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Metabolic engineering of Bacillus subtilis for production of D-lactic acid.

PubMed

Awasthi, Deepika; Wang, Liang; Rhee, Mun S; Wang, Qingzhao; Chauliac, Diane; Ingram, Lonnie O; Shanmugam, Keelnatham T

2018-02-01

Poly lactic acid (PLA) based plastics is renewable, bio-based, and biodegradable. Although present day PLA is composed of mainly L-LA, an L- and D- LA copolymer is expected to improve the quality of PLA and expand its use. To increase the number of thermotolerant microbial biocatalysts that produce D-LA, a derivative of Bacillus subtilis strain 168 that grows at 50°C was metabolically engineered. Since B. subtilis lacks a gene encoding D-lactate dehydrogenase (ldhA), five heterologous ldhA genes (B. coagulans ldhA and gldA101, and ldhA from three Lactobacillus delbrueckii) were evaluated. Corresponding D-LDHs were purified and biochemically characterized. Among these, D-LDH from L. delbrueckii subspecies bulgaricus supported the highest D-LA titer (about 1M) and productivity (2 g h -1  g cells -1 ) at 37°C (B. subtilis strain DA12). The D-LA titer at 48°C was about 0.6 M at a yield of 0.99 (g D-LA g -1 glucose consumed). Strain DA12 also fermented glucose at 48°C in mineral salts medium to lactate at a yield of 0.89 g g -1 glucose and the D-lactate titer was 180 ± 4.5 mM. These results demonstrate the potential of B. subtilis as a platform organism for metabolic engineering for production of chemicals at 48°C that could minimize process cost. © 2017 Wiley Periodicals, Inc.

Submental Ultrasonographic Parameters among Patients with Obstructive Sleep Apnea.

PubMed

Bilici, Suat; Engin, Acioglu; Ozgur, Yigit; Ozlem Onerci, Celebi; Ahmet Gorkem, Yasak; Aytul Hande, Yardimci

2017-03-01

Objective This study aimed to determine the value of submental ultrasonography (US) parameters for diagnostic workup among patients with obstructive sleep apnea (OSA) and to determine whether there is a correlation between US findings and the severity of OSA. Study Design Cross-sectional analysis. Setting Tertiary education hospital. Subjects and Methods The study included 147 patients with suspected OSA who underwent submental US to evaluate various parameters following overnight polysomnography. US findings were compared with the apnea-hypopnea index and other parameters. Results All US parameters, except for subcutaneous tissue thickness, were significantly different among patients with OSA. Of note, distance between lingual arteries (DLA), geniohyoid muscle thickness (GMT), and lateral parapharyngeal wall thickness (LPWT) were significantly greater in the patients with severe OSA than those with mild and moderate OSA ( P < .001). GMT had the strongest correlation with OSA ( r = 0.419, P < .001); LPWT and DLA also had high correlation coefficient values ( r = 0.343, P < .001, and r = 0.342, P < .001, respectively). Stepwise regression analysis showed that GMT (beta = 0.243, P = 0.004), LPWT (beta = 0.236, P = 0.004), and DLA (beta = 0.204, P = 0.008) were the most significant factors for predicting the severity of OSA according to the apnea-hypopnea index. Conclusion Submental US can be used to determine whether there is a correlation between US findings and severity of OSA. GMT could be considered a novel parameter for determining the severity of OSA.

Powered Conveyor System for Tray Pack. Short Term Project No. 1

DTIC Science & Technology

1991-08-28

responsibilities are de- scribed in the Technical and Cost Proposals for STP # 1 . 3.0 Short Term Project Activities 3.1 Technology Review & Preliminary...I - ------- F f~/ AD-A241 562: CMBAT RATION TECHNOLOGY DEMONSTRATION (CRAMTD) PtIwered onveyor Systein fbrfray Ph&k Short Tenn Piject # 1 -, TNAL...REPORT’ A ~~~STP Results and Acmolislssents (Odober 1989to~~ 1 91 Rpe ar.o.CRAMTDSlP #.L rR.-LO q~eO~4DTI.’ cRAi.4m CwcE~rA NO. DLA90088D-033 g ELECTb f C

Red Hill Administrative Order on Consent

EPA Pesticide Factsheets

Orderequiring the Navy and DLA to take actions, subject to DOH and EPA approval, to address fuel releases and implement infrastructure improvements to protect human health and the environment Red Hill Bulk Fuel Storage Facility in Hawaii.

32 CFR 323.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.1 Purpose and scope. This part 323 implements the Privacy... Privacy Program (32 CFR part 286a). It applies to Headquarters, Defense Logistics Agency (HQ DLA) and all...

76 FR 43990 - Procurement List; Proposed Additions and Deletions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-22

... Polished Nickel Finish NSN: AF430--Nameplate, Class B, USAF, Cloth, Dark Navy Blue with Silver/Gray Thread... Distribution. In 2010, the Defense Distribution Center (DDC) was renamed DLA Distribution. A process was also...

32 CFR 323.1 - Purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-07-01

... DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.1 Purpose and scope. This part 323 implements the Privacy... Privacy Program (32 CFR part 286a). It applies to Headquarters, Defense Logistics Agency (HQ DLA) and all...

32 CFR 323.1 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-07-01

... DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.1 Purpose and scope. This part 323 implements the Privacy... Privacy Program (32 CFR part 286a). It applies to Headquarters, Defense Logistics Agency (HQ DLA) and all...

Gamma-Ray Bursts: Lighting Up the High-Redshift Universe

NASA Astrophysics Data System (ADS)

Toy, Vicki Louise

Gamma-ray bursts (GRBs) are the most luminous events in the Universe with Egamma,iso ˜ 1048-54 erg. Leading models hypothesize that GRBs are created from inter- nal collisions within collimated and ultrarelativistic jets. The jets then shock-heat the surrounding material (e.g. interstellar medium) to create GRB afterglows. These afterglows are extremely useful probes of the Universe because long GRBs are (1) bright events that can be used as backlights for absorption studies, (2) able to probe at all redshifts massive stars exist, and (3) transient events that allow us to follow- up on the host galaxies at late times. In this thesis we study the environments of GRBs. We first explore the relationship between GRB and supernova (SN) using a nearby GRB-SN (GRB 130702A/SN 2013dx) at z = 0.145. There are only nine other GRB-SNe that were close enough to have extensive spectroscopic and photometric follow-up of the SN at late times. We create a quasi-bolometic light curve of SN 2013dx and fit an analytical equation to the quasi-bolometric light curve combined with measurements of the photospheric velocity to determine SN parameters: mass of 56Ni, kinetic energy, and ejecta mass. We examine the relationship between SN parameters and E gamma,iso for the 10 well-studied GRB-SNe, but find no correlations despite numerical simulation predictions that the mass of 56Ni should correlate with the degree of asymmetry. We then move to larger distance scales and use GRB afterglows as bright back- lights to study distant galaxies. We examine the galactic environments of Damped Lyman-alpha systems (DLAs; NHI ≥ 1020.3 cm-2 ) identified with GRB afterglows at z ˜ 2 - 6. We use late-time photometry after the GRB afterglow has faded to determine star formation rates (SFRs) from rest-frame ultraviolet measurements or spectral energy distribution (SED) models from multiband photometry. We com- pare our sample's SFRs to a sample of quasars (QSOs) DLA host galaxies. Despite the overlapping NHI and redshift ranges, our GRB-DLA galaxies have much larger SFRs than the QSO-DLA host galaxy sample; this may suggest that the QSO-DLA and GRB-DLA galaxy populations are different. We also compare star formation efficiencies to the local Universe and simulations at z = 3. A large portion of this thesis has focused on the development of a new ground- based GRB afterglow follow-up instrument, the Rapid infrared IMAger-Spectrometer (RIMAS), that will target high-redshift GRB afterglows to study early galaxy envi- ronments. RIMAS covers 0.97-2.37 mum and can simultaneously observe two band-passes in any observing mode: photometry, low-resolution spectroscopy (R ˜ 30), or high-resolution spectroscopy (R ˜ 4000). In particular, this thesis focuses on RIMAS's three detectors: two science grade Teledyne HgCdTe Astronomy Wide Area Infrared Imager with 2K x 2K, Reference Pixels and Guide Mode (H2RG) and a slit-viewer Spitzer Legacy Indium-Antimonide (InSb) array. We describe the detector hardware and characterization in detail and discuss general infrared detector troubleshooting methods at both cryogenic and room temperatures. Several software packages have been developed for RIMAS throughout this thesis work. We introduce RIMAS's quick reduction pipeline that takes raw images from a single acquisition and returns a single result frame. We then present a generalized data reduction pipeline that we have tested on two currently operational photometers. We also describe our detailed and realistic RIMAS throughput models for all three observing modes as well as our online observer calculators with these throughput models. All of our data products are open source and are publicly available on Github repositories with detailed documentation.

Self-affine fractal growth front of Aspergillus oryzae

NASA Astrophysics Data System (ADS)

Matsuura, Shu; Miyazima, Sasuke

1992-12-01

Aspergillus oryzae have been grown in various environmental conditions and analyzed from the viewpoint of self-affinity. The growth behavior can be described by the Eden model in favorable conditions, and by DLA in unfavorable conditions.

32 CFR Appendix A to Part 222 - Addressing MDR Requests

Code of Federal Regulations, 2013 CFR

2013-07-01

... Declassification Division, Suite 02F09-02, 4800 Mark Center Drive, Alexandria, VA 22350-3100. EXCEPTION: DoD...) Defense Logistics Agency. Defense Logistics Agency, Attention: DLA/DSS-S, 8725 John J. Kingman Road, Suite...

32 CFR Appendix A to Part 222 - Addressing MDR Requests

Code of Federal Regulations, 2012 CFR

2012-07-01

... Declassification Division, Suite 02F09-02, 4800 Mark Center Drive, Alexandria, VA22350-3100. EXCEPTION: DoD...) Defense Logistics Agency. Defense Logistics Agency, Attention: DLA/DSS-S, 8725 John J. Kingman Road, Suite...

32 CFR Appendix A to Part 222 - Addressing MDR Requests

Code of Federal Regulations, 2014 CFR

2014-07-01

... Declassification Division, Suite 02F09-02, 4800 Mark Center Drive, Alexandria, VA 22350-3100. EXCEPTION: DoD...) Defense Logistics Agency. Defense Logistics Agency, Attention: DLA/DSS-S, 8725 John J. Kingman Road, Suite...

Homo-fermentative production of D-lactic acid by Lactobacillus sp. employing casein whey permeate as a raw feed-stock.

PubMed

Prasad, Saurav; Srikanth, Katla; Limaye, Anil M; Sivaprakasam, Senthilkumar

2014-06-01

Casein whey permeate (CWP), a lactose-enriched dairy waste effluent, is a viable feed stock for the production of value-added products. Two lactic acid bacteria were cultivated in a synthetic casein whey permeate medium with or without pH control. Lactobacillus lactis ATCC 4797 produced D-lactic acid (DLA) at 12.5 g l(-1) in a bioreactor. The values of Leudking-Piret model parameters suggested that lactate was a growth-associated product. Batch fermentation was also performed employing CWP (35 g lactose l(-1)) with casein hydrolysate as a nitrogen supplement in a bioreactor. After 40 h, L. lactis produced 24.3 g lactic acid l(-1) with an optical purity >98 %. Thus CWP may be regarded as a potential feed-stock for DLA production.

Nucleation of Organic Molecules via a Hot Precursor State: Pentacene on Amorphous Mica

PubMed Central

2013-01-01

Organic thin films have attracted considerable interest due to their applicability in organic electronics. The classical scenario for thin film nucleation is the diffusion-limited aggregation (DLA). Recently, it has been shown that organic thin film growth is better described by attachment-limited aggregation (ALA). However, in both cases, an unusual relationship between the island density and the substrate temperature was observed. Here, we present an aggregation model that goes beyond the classical DLA or ALA models to explain this behavior. We propose that the (hot) molecules impinging on the surface cannot immediately equilibrate to the substrate temperature but remain in a hot precursor state. In this state, the molecules can migrate considerable distances before attaching to a stable or unstable island. This results in a significantly smaller island density than expected by assuming fast equilibration and random diffusion. We have applied our model to pentacene film growth on amorphous Muscovite mica. PMID:24340130

Observed Faraday Effects in Damped Lyα Absorbers and Lyman Limit Systems: The Magnetized Environment of Galactic Building Blocks at Redshift = 2

NASA Astrophysics Data System (ADS)

Farnes, J. S.; Rudnick, L.; Gaensler, B. M.; Haverkorn, M.; O'Sullivan, S. P.; Curran, S. J.

2017-06-01

Protogalactic environments are typically identified using quasar absorption lines and can manifest as Damped Lyman-alpha Absorbers (DLAs) and Lyman Limit Systems (LLSs). We use radio observations of Faraday effects to test whether these galactic building blocks host a magnetized medium, by combining DLA and LLS detections with 1.4 GHz polarization data from the NRAO VLA Sky Survey (NVSS). We obtain a control, a DLA, and an LLS sample consisting of 114, 19, and 27 lines of sight, respectively. Using a Bayesian framework and weakly informative priors, we are unable to detect either coherent or random magnetic fields in DLAs: the regular coherent fields must be ≤slant 2.8 μG, and the lack of depolarization suggests the weakly magnetized gas in DLAs is non-turbulent and quiescent. However, we find a mild suggestive indication that LLSs have coherent magnetic fields, with a 71.5% probability that LLSs have higher | {RM}| than a control, although this is sensitive to the redshift distribution. We also find a strong indication that LLSs host random magnetic fields, with a 95.5% probability that LLS lines of sight have lower polarized fractions than a control. The regular coherent fields within the LLSs must be ≤slant 2.4 μG, and the magnetized gas must be highly turbulent with a typical turbulent length scale on the order of ≈5-20 pc. Our results are consistent with the standard dynamo paradigm, whereby magnetism in protogalaxies increases in coherence over cosmic time, and with a hierarchical galaxy formation scenario, with the DLAs and LLSs exploring different stages of magnetic field evolution in galaxies.

Quasar 2175 Å dust absorbers - I. Metallicity, depletion pattern and kinematics

NASA Astrophysics Data System (ADS)

Ma, Jingzhe; Ge, Jian; Zhao, Yinan; Prochaska, J. Xavier; Zhang, Shaohua; Ji, Tuo; Schneider, Donald P.

2017-12-01

We present 13 new 2175 Å dust absorbers at zabs = 1.0-2.2 towards background quasars from the Sloan Digital Sky Survey. These absorbers are examined in detail using data from the Echelle Spectrograph and Imager (ESI) on the Keck II telescope. Many low-ionization lines including Fe II, Zn II, Mg II, Si II, Al II, Ni II, Mn II, Cr II, Ti II and Ca II are present in the same absorber that gives rise to the 2175 Å bump. The relative metal abundances (with respect to Zn) demonstrate that the depletion patterns of our 2175 Å dust absorbers resemble that of the Milky Way clouds although some are disc-like and some are halo-like. The 2175 Å dust absorbers have significantly higher depletion levels compared to literature damped Lyman α absorbers (DLAs) and sub-DLAs. The dust depletion level indicator [Fe/Zn] tends to anticorrelate with bump strengths. The velocity profiles from the Keck/ESI spectra also provide kinematical information on the dust absorbers. The dust absorbers are found to have multiple velocity components with velocity widths extending from ∼100 to ∼600 km s-1, which are larger than those of most DLAs and sub-DLAs. Assuming the velocity width is a reliable tracer of stellar mass, the host galaxies of 2175 Å dust absorbers are expected to be more massive than DLA/sub-DLA hosts. Not all of the 2175 Å dust absorbers are intervening systems towards background quasars. The absorbers towards quasars J1006+1538 and J1047+3423 are proximate systems that could be associated with the quasar itself or the host galaxy.

Interstellar Gas-phase Element Depletions in the Small Magellanic Cloud: A Guide to Correcting for Dust in QSO Absorption Line Systems

NASA Astrophysics Data System (ADS)

Jenkins, Edward B.; Wallerstein, George

2017-04-01

We present data on the gas-phase abundances for 9 different elements in the interstellar medium of the Small Magellanic Cloud (SMC), based on the strengths of ultraviolet absorption features over relevant velocities in the spectra of 18 stars within the SMC. From this information and the total abundances defined by the element fractions in young stars in the SMC, we construct a general interpretation on how these elements condense into solid form onto dust grains. As a group, the elements Si, S, Cr, Fe, Ni, and Zn exhibit depletion sequences similar to those in the local part of our Galaxy defined by Jenkins. The elements Mg and Ti deplete less rapidly in the SMC than in the Milky Way, and Mn depletes more rapidly. We speculate that these differences might be explained by the different chemical affinities to different existing grain substrates. For instance, there is evidence that the mass fractions of polycyclic aromatic hydrocarbons in the SMC are significantly lower than those in the Milky Way. We propose that the depletion sequences that we observed for the SMC may provide a better model for interpreting the element abundances in low-metallicity Damped Lyman Alpha (DLA) and sub-DLA absorption systems that are recorded in the spectra of distant quasars and gamma-ray burst afterglows. Based on observations with the NASA/ESA Hubble Space Telescope and additional data obtained from the Data Archive at the Space Telescope Science Institute, which is operated by the Associations of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. These observations are associated with program nr. 13778.

32 CFR 323.4 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.4 Responsibilities. (a) Headquarters Defense Logistics...) Formulate policies, procedures, and standards necessary for uniform compliance with the Privacy Act by DLA...

Aggregates, broccoli and cauliflower

NASA Astrophysics Data System (ADS)

Grey, Francois; Kjems, Jørgen K.

1989-09-01

Naturally grown structures with fractal characters like broccoli and cauliflower are discussed and compared with DLA-type aggregates. It is suggested that the branching density can be used to characterize the growth process and an experimental method to determine this parameter is proposed.

Properties of the simian virus 40 (SV40) large T antigens encoded by SV40 mutants with deletions in gene A.

PubMed Central

Cole, C N; Tornow, J; Clark, R; Tjian, R

1986-01-01

The biochemical properties of the large T antigens encoded by simian virus 40 (SV40) mutants with deletions at DdeI sites in the SV40 A gene were determined. Mutant large T antigens containing only the first 138 to 140 amino acids were unable to bind to the SV40 origin of DNA replication as were large T antigens containing at their COOH termini 96 or 97 amino acids encoded by the long open reading frame located between 0.22 and 0.165 map units (m.u.). All other mutant large T antigens were able to bind to the SV40 origin of replication. Mutants with in-phase deletions at 0.288 and 0.243 m.u. lacked ATPase activity, but ATPase activity was normal in mutants lacking origin-binding activity. The 627-amino acid large T antigen encoded by dlA2465, with a deletion at 0.219 m.u., was the smallest large T antigen displaying ATPase activity. Mutant large T antigens with the alternate 96- or 97-amino acid COOH terminus also lacked ATPase activity. All mutant large T antigens were found in the nuclei of infected cells; a small amount of large T with the alternate COOH terminus was also located in the cytoplasm. Mutant dlA2465 belonged to the same class of mutants as dlA2459. It was unable to form plaques on CV-1p cells at 37 or 32 degrees C but could form plaques on BSC-1 monolayers at 37 degrees C but not at 32 degrees C. It was positive for viral DNA replication and showed intracistronic complementation with any group A mutant whose large T antigen contained a normal carboxyl terminus. These findings and those of others suggest that both DNA binding and ATPase activity are required for the viral DNA replication function of large T antigen, that these two activities must be located on the same T antigen monomer, and that these two activities are performed by distinct domains of the polypeptide. These domains are distinct and separable from the domain affected by the mutation of dlA2465 and indicate that SV40 large T antigen is made up of at least three separate functional domains. Images PMID:3003386

The Chemical Evolution of QSO Absorbers

NASA Astrophysics Data System (ADS)

Ellison, Sara L.

2000-06-01

The chemical evolution of the high redshift intergalactic and interstellar media of galaxies is studied using QSO absorption lines. The redshift evolution of damped Lyman alpha (DLA) system metallicity is studied down to z=0.5, and no significant increase in metals is found. The CIV/HI ratio in the Lyman alpha forest is investigated at z approximately 3 and traces of are metals found in the low density HI gas with optical depth of around 1. Finally, a new survey for DLAs in a radio-selected sample of QSOs is presented, with the aim of determining whether a significant dust bias may have affected previous surveys.

Effect of Biodiesel on Diesel Engine Nitrogen Oxide and Other Regulated Emissions

DTIC Science & Technology

2006-05-01

DENIX Defense Environmental Network & Information Exchange DLA Defense Logistics Agency DNPH Dinitrophenylhydrazine DoD Department of... Dinitrophenylhydrazine (DNPH) cartridges and analyzed using a high-performance liquid chromatograph with ultraviolet detection, as per an AO/AQIRP method (Reference

Loglines. January - February 2012

DTIC Science & Technology

2012-02-01

to that organization’s lineup since 00 , Lee said. Some of those were already used by commercial industry but simply needed to be brought into the...recently began updating and rewriting the Defense Logistics Acquisition Directive, the document that establishes DLA procedures relating to the

Unit Home

Science.gov Websites

Commanding Officer Sergeant Major Sections S1 - Administration S3 - Training S4 - Logistics Career Planner Operation Command, Pacific Hawaii Judicial Circuit Consolidated Storage Program DLA Customer Support Warrior Detachment College of Distance Education & Training Patrol and Reconnaissance Wing TWO Patrol

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luszczek, Piotr R; Tomov, Stanimire Z; Dongarra, Jack J

We present an efficient and scalable programming model for the development of linear algebra in heterogeneous multi-coprocessor environments. The model incorporates some of the current best design and implementation practices for the heterogeneous acceleration of dense linear algebra (DLA). Examples are given as the basis for solving linear systems' algorithms - the LU, QR, and Cholesky factorizations. To generate the extreme level of parallelism needed for the efficient use of coprocessors, algorithms of interest are redesigned and then split into well-chosen computational tasks. The tasks execution is scheduled over the computational components of a hybrid system of multi-core CPUs andmore » coprocessors using a light-weight runtime system. The use of lightweight runtime systems keeps scheduling overhead low, while enabling the expression of parallelism through otherwise sequential code. This simplifies the development efforts and allows the exploration of the unique strengths of the various hardware components.« less

32 CFR 1288.4 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Responsibilities. 1288.4 Section 1288.4 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.4 Responsibilities. (a) HQ DLA. (1) The command security...

32 CFR 1292.5 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Procedures. 1292.5 Section 1292.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.5 Procedures. (a) Security regulations and orders will be...

32 CFR 1288.5 - Procedures.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Procedures. 1288.5 Section 1288.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION... inspections are not mandatory for DLA activities located in areas not requiring such inspections. (d...

32 CFR 1288.5 - Procedures.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Procedures. 1288.5 Section 1288.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION... inspections are not mandatory for DLA activities located in areas not requiring such inspections. (d...

32 CFR 1288.5 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Procedures. 1288.5 Section 1288.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION... inspections are not mandatory for DLA activities located in areas not requiring such inspections. (d...

32 CFR 1288.5 - Procedures.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Procedures. 1288.5 Section 1288.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION... inspections are not mandatory for DLA activities located in areas not requiring such inspections. (d...

32 CFR 1288.4 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Responsibilities. 1288.4 Section 1288.4 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.4 Responsibilities. (a) HQ DLA. (1) The command security...

32 CFR 1292.5 - Procedures.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Procedures. 1292.5 Section 1292.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.5 Procedures. (a) Security regulations and orders will be...

32 CFR 1288.4 - Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Responsibilities. 1288.4 Section 1288.4 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.4 Responsibilities. (a) HQ DLA. (1) The command security...

32 CFR 1292.5 - Procedures.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Procedures. 1292.5 Section 1292.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.5 Procedures. (a) Security regulations and orders will be...

32 CFR 1292.5 - Procedures.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Procedures. 1292.5 Section 1292.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.5 Procedures. (a) Security regulations and orders will be...

32 CFR 1288.4 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Responsibilities. 1288.4 Section 1288.4 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.4 Responsibilities. (a) HQ DLA. (1) The command security...

32 CFR 1292.5 - Procedures.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Procedures. 1292.5 Section 1292.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.5 Procedures. (a) Security regulations and orders will be...

32 CFR 1288.4 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Responsibilities. 1288.4 Section 1288.4 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.4 Responsibilities. (a) HQ DLA. (1) The command security...

Template mediated protein self-assembly as a valuable tool in regenerative therapy.

PubMed

Kundu, B; Eltohamy, M; Yadavalli, V K; Reis, R L; Kim, H W

2018-04-11

The assembly of natural proteinaceous biopolymers into macro-scale architectures is of great importance in synthetic biology, soft-material science and regenerative therapy. The self-assembly of protein tends to be limited due to anisotropic interactions among protein molecules, poor solubility and stability. Here, we introduce a unique platform to self-immobilize diverse proteins (fibrous and globular, positively and negatively charged, low and high molecular weight) using silicon surfaces with pendant -NH 2 groups via a facile one step diffusion limited aggregation (DLA) method. All the experimental proteins (type I collagen, bovine serum albumin and cytochrome C) self-assemble into seaweed-like branched dendritic architectures via classical DLA in the absence of any electrolytes. The notable differences in branching architectures are due to dissimilarities in protein colloidal sub-units, which is typical for each protein type, along with the heterogeneous distribution of surface -NH 2 groups. Fractal analysis of assembled structures is used to explain the underlying route of fractal deposition; which concludes how proteins with different functionality can yield similar assembly. Further, the nano-micro-structured surfaces can be used to provide functional topographical cues to study cellular responses, as demonstrated using rat bone marrow stem cells. The results indicate that the immobilization of proteins via DLA does not affect functionality, instead serving as topographical cues to guide cell morphology. This indicates a promising design strategy at the tissue-material interface and is anticipated to guide future surface modifications. A cost-effective standard templating strategy is therefore proposed for fundamental and applied particle aggregation studies, which can be used at multiple length scales for biomaterial design and surface reformation.

Preliminary results on performance of new ultra-fast static positioning module - POZGEO-2 in areas outside the ASG-EUPOS network

NASA Astrophysics Data System (ADS)

Paziewski, Jacek; Krukowska, Marta; Wielgosz, Paweł

2014-06-01

The presented preliminary research concerns the accuracy and reliability of new ultra-fast static positioning module - POZGEO-2 - in case of processing GPS data collected outside the ASG-EUPOS network. Such a case requires extrapolation of the network-derived atmospheric corrections which limits correction accuracy and, therefore, has adverse effect on the carrier phase ambiguity resolution. The presented processing tests are based on processing 5-minute long observing sessions and show that precise positioning can be supported up to 35 km from the ASG-EUPOS borders. This means that precise positioning with POZGEO-2 module can be assured for the most of the border areas of Poland. W pracy prezentowane są badania dotyczące dokładności i wiarygodności pozycji wyznaczanej z wykorzystaniem nowego modułu ultra-szybkiego pozycjonowania - POZGEO-2 opracowanego dla systemu ASG-EUPOS. Przedstawione testy obliczeniowe dotyczą szczególnego przypadku wyznaczania pozycji, gdy użytkownik znajduje się poza granicami sieci stacji referencyjnych. W takich warunkach wymagana jest ekstrapolacja sieciowych poprawek atmosferycznych. Wpływa to negatywnie na dokładność tych poprawek i może doprowadzić do sytuacji, w której wyznaczenie nieoznaczoności będzie niemożliwe. Prezentowane badania oparte są na pięciominutowych sesjach obserwacyjnych i pokazują, że poprawki mogą być ekstrapolowane dla obszarów położonych do około 35 km od granic sieci ASG-EUPOS. Oznacza to, że w praktyce precyzyjne pozycjonowanie ultra-szybkie z użyciem modułu POZGEO-2 może być zapewnione dla niemal całego obszaru Polski

Design pattern mining using distributed learning automata and DNA sequence alignment.

PubMed

Esmaeilpour, Mansour; Naderifar, Vahideh; Shukur, Zarina

2014-01-01

Over the last decade, design patterns have been used extensively to generate reusable solutions to frequently encountered problems in software engineering and object oriented programming. A design pattern is a repeatable software design solution that provides a template for solving various instances of a general problem. This paper describes a new method for pattern mining, isolating design patterns and relationship between them; and a related tool, DLA-DNA for all implemented pattern and all projects used for evaluation. DLA-DNA achieves acceptable precision and recall instead of other evaluated tools based on distributed learning automata (DLA) and deoxyribonucleic acid (DNA) sequences alignment. The proposed method mines structural design patterns in the object oriented source code and extracts the strong and weak relationships between them, enabling analyzers and programmers to determine the dependency rate of each object, component, and other section of the code for parameter passing and modular programming. The proposed model can detect design patterns better that available other tools those are Pinot, PTIDEJ and DPJF; and the strengths of their relationships. The result demonstrate that whenever the source code is build standard and non-standard, based on the design patterns, then the result of the proposed method is near to DPJF and better that Pinot and PTIDEJ. The proposed model is tested on the several source codes and is compared with other related models and available tools those the results show the precision and recall of the proposed method, averagely 20% and 9.6% are more than Pinot, 27% and 31% are more than PTIDEJ and 3.3% and 2% are more than DPJF respectively. The primary idea of the proposed method is organized in two following steps: the first step, elemental design patterns are identified, while at the second step, is composed to recognize actual design patterns.

32 CFR 1292.3 - Background.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Background. 1292.3 Section 1292.3 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.3 Background. Section 21 of the Internal Security Act of 1950...

77 FR 5779 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-06

...; Comment Request AGENCY: Defense Logistics Agency, DLA Small Business Programs, DoD. ACTION: Notice... Logistics Agency announces the proposed extension of a public information collection and seeks public... Center Drive, 2nd Floor, East Tower, Suite 02G09, Alexandria, VA 22350- 3100. Instructions: All...

32 CFR 1292.3 - Background.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Background. 1292.3 Section 1292.3 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.3 Background. Section 21 of the Internal Security Act of 1950...

32 CFR 1292.3 - Background.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Background. 1292.3 Section 1292.3 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.3 Background. Section 21 of the Internal Security Act of 1950...

32 CFR 1292.3 - Background.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Background. 1292.3 Section 1292.3 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.3 Background. Section 21 of the Internal Security Act of 1950...

32 CFR 1292.3 - Background.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Background. 1292.3 Section 1292.3 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.3 Background. Section 21 of the Internal Security Act of 1950...

Fractal analysis of Xylella fastidiosa biofilm formation

NASA Astrophysics Data System (ADS)

Moreau, A. L. D.; Lorite, G. S.; Rodrigues, C. M.; Souza, A. A.; Cotta, M. A.

2009-07-01

We have investigated the growth process of Xylella fastidiosa biofilms inoculated on a glass. The size and the distance between biofilms were analyzed by optical images; a fractal analysis was carried out using scaling concepts and atomic force microscopy images. We observed that different biofilms show similar fractal characteristics, although morphological variations can be identified for different biofilm stages. Two types of structural patterns are suggested from the observed fractal dimensions Df. In the initial and final stages of biofilm formation, Df is 2.73±0.06 and 2.68±0.06, respectively, while in the maturation stage, Df=2.57±0.08. These values suggest that the biofilm growth can be understood as an Eden model in the former case, while diffusion-limited aggregation (DLA) seems to dominate the maturation stage. Changes in the correlation length parallel to the surface were also observed; these results were correlated with the biofilm matrix formation, which can hinder nutrient diffusion and thus create conditions to drive DLA growth.

Damped and sub-damped Lyman-α absorbers in z > 4 QSOs

NASA Astrophysics Data System (ADS)

Guimarães, R.; Petitjean, P.; de Carvalho, R. R.; Djorgovski, S. G.; Noterdaeme, P.; Castro, S.; Poppe, P. C. Da R.; Aghaee, A.

2009-12-01

We present the results of a survey of damped (DLA, log~N(H i)>20.3) and sub-damped Lyman-α systems (19.5 2.55 along the lines-of-sight to 77 quasars with emission redshifts in the range 419.5 were detected of which 40 systems are damped Lyman-α systems for an absorption length of Δ X = 378. About half of the lines of sight of this homogeneous survey have never been investigated for DLAs. We study the evolution with redshift of the cosmological density of the neutral gas and find, consistent with previous studies at similar resolution, that ΩDLA, H_I decreases at z>3.5. The overall cosmological evolution of Ω_HI shows a peak around this redshift. The H i column density distribution for log N(H i)≥20.3 is fitted, consistent with previous surveys, with a single power-law of index α ˜ -1.8 ±0.25. This power-law overpredicts data at the high-end and a second, much steeper, power-law (or a gamma function) is needed. There is a flattening of the function at lower H i column densities with an index of α ˜ -1.4 for the column density range log N(H i)=19.5-21. The fraction of H i mass in sub-DLAs is of the order of 30%. The H i column density distribution does not evolve strongly from z˜ 2.5 to z˜ 4.5. The observations reported here were obtained with the W. M. Keck Observatory, which is operated by the California Association for Research in Astronomy, a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. Tables 1, 2 and Appendices are only available in electronic form at http://www.aanda.org

Commercial Off-The-Shelf (COTS) Parts Risk and Reliability User and Application Guide

NASA Technical Reports Server (NTRS)

White, Mark

2017-01-01

All COTS parts are not created equal. Because they are not created equal, the notion that one can force the commercial industry to follow a set of military specifications and standards, along with the certifications, audits and qualification commitments that go with them, is unrealistic for the sale of a few parts. The part technologies that are Defense Logistics Agency (DLA) certified or Military Specification (MS) qualified, are several generations behind the state-of-the-art high-performance parts that are required for the compact, higher performing systems for the next generation of spacecraft and instruments. The majority of the part suppliers are focused on the portion of the market that is producing high-tech commercial products and systems. To that end, in order to compete in the high performance and leading edge advanced technological systems, an alternative approach to risk assessment and reliability prediction must be considered.

32 CFR 1285.2 - Policy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... information concerning the activities of its Government. DLA policy is to conduct its activities in an open... activities in an open manner consistent with the need for security and adherence to other requirements of law..., where a public reading room also serves as an activity's library, restricted publications may be...

32 CFR 1285.2 - Policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... information concerning the activities of its Government. DLA policy is to conduct its activities in an open... activities in an open manner consistent with the need for security and adherence to other requirements of law..., where a public reading room also serves as an activity's library, restricted publications may be...

Defense Logistics Agency 1995 Defense Base Realignment and Closure Data Collection Process for the Evaluation Phase.

DTIC Science & Technology

1995-05-04

Commission. The specific objective for the audit was to determine whether the evaluation process that the DLA used to develop recommendations reported to the...1995 Commission was consistently applied and adequately supported. The audit also reviewed applicable management controls.

32 CFR 300.4 - Policy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAM DEFENSE LOGISTICS AGENCY FREEDOM OF INFORMATION ACT PROGRAM General Provisions § 300.4 Policy. DLA... Requester Service Center contact information. (1) To meet the requirements of Executive Order 13392, each FOIA Requester Service Center shall have an internet Web site that serves to educate the public on the...

32 CFR 34.12 - Payment.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Program Management § 34.12 Payment. (a) Methods available. Payment methods for awards with for-profit... Administration Services Components,” DLAH 4105.4, which can be obtained from either: Defense Logistics Agency...-6220; or the Defense Contract Management Command home page at http://www.dcmc.dcrb.dla.mil. 2 See...

32 CFR 1288.6 - Forms and reports.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Forms and reports. 1288.6 Section 1288.6 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.6 Forms and reports. (a) DLA form 1454 will be prepared...

32 CFR 323.2 - Policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Policy. 323.2 Section 323.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.2 Policy. It is the policy of DLA to safeguard personal information...

77 FR 14005 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

...; Comment Request AGENCY: Defense Logistics Agency, DoD. ACTION: Notice. SUMMARY: In compliance with Section 3506(c)(2)(A) of the Paperwork Reduction Act of 1995, the Defense Logistics Agency announces a proposed... instruments, please write to the Defense Logistics Agency Headquarters, ATTN: Ms. Kathi Snyder, DLA Office of...

41 CFR 101-26.603 - Electronic items available from the Defense Logistics Agency.

Code of Federal Regulations, 2014 CFR

2014-07-01

... available from the Defense Logistics Agency. 101-26.603 Section 101-26.603 Public Contracts and Property... items available from the Defense Logistics Agency. Executive agencies shall satisfy their requirements... classes 5940, 5970, 5975, 5977, and 5995) from the Defense Electronic Supply Center (DESC), DLA...

41 CFR 101-26.603 - Electronic items available from the Defense Logistics Agency.

Code of Federal Regulations, 2011 CFR

2011-07-01

... available from the Defense Logistics Agency. 101-26.603 Section 101-26.603 Public Contracts and Property... items available from the Defense Logistics Agency. Executive agencies shall satisfy their requirements... classes 5940, 5970, 5975, 5977, and 5995) from the Defense Electronic Supply Center (DESC), DLA...

78 FR 65300 - Notice of Availability (NOA) for General Purpose Warehouse and Information Technology Center...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-31

... (NOA) for General Purpose Warehouse and Information Technology Center Construction (GPW/IT)--Tracy Site-- Environmental Assessment AGENCY: Defense Logistics Agency, DoD. ACTION: Notice of Availability (NOA) for GPW/IT--Tracy Site-- Environmental Assessment. SUMMARY: The Defense Logistics Agency (DLA) announces the...

41 CFR 101-26.603 - Electronic items available from the Defense Logistics Agency.

Code of Federal Regulations, 2012 CFR

2012-07-01

... available from the Defense Logistics Agency. 101-26.603 Section 101-26.603 Public Contracts and Property... items available from the Defense Logistics Agency. Executive agencies shall satisfy their requirements... classes 5940, 5970, 5975, 5977, and 5995) from the Defense Electronic Supply Center (DESC), DLA...

41 CFR 101-26.603 - Electronic items available from the Defense Logistics Agency.

Code of Federal Regulations, 2010 CFR

2010-07-01

... available from the Defense Logistics Agency. 101-26.603 Section 101-26.603 Public Contracts and Property... items available from the Defense Logistics Agency. Executive agencies shall satisfy their requirements... classes 5940, 5970, 5975, 5977, and 5995) from the Defense Electronic Supply Center (DESC), DLA...

78 FR 78943 - Notice of Availability (NOA) of an Environmental Assessment (EA) for the Temporary Storage of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

... Defense Supply Center Richmond, Virginia AGENCY: Defense Logistics Agency, DoD. ACTION: Notice of... at Defense Supply Center Richmond, Virginia. SUMMARY: The Defense Logistics Agency (DLA) announces... associated with the proposed action to temporarily store wheeled tactical vehicles at Defense Supply Center...

32 CFR 300.7 - FOIA request processing procedures.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE LOGISTICS AGENCY FREEDOM OF INFORMATION ACT PROGRAM... request is perfected. When a DLA FOIA Requester Service Center receives a request for records that clearly... Service Center has a telephone line to inform the requester of the status of their request (see Appendix A...

41 CFR 101-26.603 - Electronic items available from the Defense Logistics Agency.

Code of Federal Regulations, 2013 CFR

2013-07-01

... available from the Defense Logistics Agency. 101-26.603 Section 101-26.603 Public Contracts and Property... items available from the Defense Logistics Agency. Executive agencies shall satisfy their requirements... classes 5940, 5970, 5975, 5977, and 5995) from the Defense Electronic Supply Center (DESC), DLA...

A Cost Analysis of Forward Positioning Material in the Fifth Fleet Area of Responsibility

DTIC Science & Technology

2014-12-01

CTF combined task force CY calendar year DDC defense distribution center DDNB Defense Depot Navy Detachment, Bahrain DHL DHL Airways DLA...items from Bahrain to the requesting unit.  Defense Distribution Center ( DDC )– DDC is concerned with getting the requested national item

Characterization of partial resistance to black spot disease of Rosa spp.

USDA-ARS?s Scientific Manuscript database

Black spot disease (BSD) is one of the most serious diseases of garden roses. Both complete (vertical) resistance and partial (horizontal) resistance have been identified in 16 rose genotypes using two laboratory assays, the detached leaf assay (DLA) and the whole plant inoculation (WPI) approaches...

32 CFR 323.6 - Forms and reports.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Forms and reports. 323.6 Section 323.6 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.6 Forms and reports. DLA activities may be required to...

32 CFR 323.6 - Forms and reports.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Forms and reports. 323.6 Section 323.6 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.6 Forms and reports. DLA activities may be required to...

32 CFR 323.6 - Forms and reports.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Forms and reports. 323.6 Section 323.6 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.6 Forms and reports. DLA activities may be required to...

32 CFR 323.2 - Policy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Policy. 323.2 Section 323.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.2 Policy. It is the policy of DLA to safeguard personal information...

32 CFR 323.3 - Policy.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Policy. 323.3 Section 323.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.3 Policy. DLA adopts and supplements the DoD Privacy Program policy...

32 CFR 1288.6 - Forms and reports.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Forms and reports. 1288.6 Section 1288.6 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.6 Forms and reports. (a) DLA form 1454 will be prepared...

32 CFR 323.2 - Policy.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Policy. 323.2 Section 323.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.2 Policy. It is the policy of DLA to safeguard personal information...

32 CFR 1288.6 - Forms and reports.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Forms and reports. 1288.6 Section 1288.6 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.6 Forms and reports. (a) DLA form 1454 will be prepared...

32 CFR 323.3 - Policy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Policy. 323.3 Section 323.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.3 Policy. DLA adopts and supplements the DoD Privacy Program policy...

32 CFR 1288.6 - Forms and reports.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Forms and reports. 1288.6 Section 1288.6 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.6 Forms and reports. (a) DLA form 1454 will be prepared...

32 CFR 1288.6 - Forms and reports.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Forms and reports. 1288.6 Section 1288.6 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS REGISTRATION OF PRIVATELY OWNED MOTOR VEHICLES § 1288.6 Forms and reports. (a) DLA form 1454 will be prepared...

32 CFR 634.50 - Towing and storage.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Towing and storage. 634.50 Section 634.50 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND... Towing and storage. (a) Impounded POVs may be towed and stored by either the Services and DLA or a...

32 CFR 634.50 - Towing and storage.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 4 2014-07-01 2013-07-01 true Towing and storage. 634.50 Section 634.50 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND... Towing and storage. (a) Impounded POVs may be towed and stored by either the Services and DLA or a...

32 CFR 634.50 - Towing and storage.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 4 2011-07-01 2011-07-01 false Towing and storage. 634.50 Section 634.50 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND... Towing and storage. (a) Impounded POVs may be towed and stored by either the Services and DLA or a...

32 CFR 634.50 - Towing and storage.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 4 2013-07-01 2013-07-01 false Towing and storage. 634.50 Section 634.50 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND... Towing and storage. (a) Impounded POVs may be towed and stored by either the Services and DLA or a...

78 FR 57622 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-19

... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DoD-2013-OS-0194] Proposed Collection; Comment Request AGENCY: Defense Logistics Agency (DLA), DoD. ACTION: Notice. SUMMARY: In compliance with..., Department of Defense. [FR Doc. 2013-22789 Filed 9-18-13; 8:45 am] BILLING CODE 5001-06-P ...

Geotechnical Risk Classification for Underground Mines / Klasyfikacja Poziomu Zagrożenia Geotechnicznego W Kopalniach Podziemnych

NASA Astrophysics Data System (ADS)

Mishra, Ritesh Kumar; Rinne, Mikael

2015-03-01

Underground mining activities are prone to major hazards largely owing to geotechnical reasons. Mining combined with the confined working space and uncertain geotechnical data leads to hazards having the potential of catastrophic consequences. These incidents have the potential of causing multiple fatalities and large financial damages. Use of formal risk assessment in the past has demonstrated an important role in the prediction and prevention of accidents in risk prone industries such as petroleum, nuclear and aviation. This paper proposes a classification system for underground mining operations based on their geotechnical risk levels. The classification is done based on the type of mining method employed and the rock mass in which it is carried out. Mining methods have been classified in groups which offer similar geotechnical risk. The rock mass classification has been proposed based on bulk rock mass properties which are collected as part of the routine mine planning. This classification has been subdivided for various stages of mine planning to suit the extent of available data. Alpha-numeric coding has been proposed to identify a mining operation based on the competency of rock and risk of geotechnical failures. This alpha numeric coding has been further extended to identify mining activity under `Geotechnical Hazard Potential (GHP)'. GHP has been proposed to be used as a preliminary tool of risk assessment and risk ranking for a mining activity. The aim of such classification is to be used as a guideline for the justification of a formal geotechnical risk assessment. Górnictwo podziemne pociąga za sobą różnorakie zagrożenia spowodowane przez uwarunkowania geotechniczne. Urabianie złoża w połączeniu z pracą w zamkniętej przestrzeni oraz z niepewnymi danymi geotechnicznymi powodować może zagrożenia, które w konsekwencji prowadzić mogą do wypadków, a te potencjalnie powodować mogą skutki śmiertelne dla osób oraz poważne straty finansowe. Wykorzystanie przepisowych metod oceny ryzyka w przeszłości wykazało ich istotną rolę w przewidywaniu i zapobieganiu wypadkom i zagrożeniom w dziedzinach najbardziej na nie narażonych, a więc w przemyśle naftowym, jądrowym oraz w lotnictwie. W niniejszej pracy zaproponowano system klasyfikacji operacji w górnictwie podziemnym w oparciu o poziom zagrożenia geotechnicznego. Klasyfikacji dokonano uwzględniając zastosowana metodę urabiania oraz rodzaj urabianego górotworu. Przedstawiono kategorie metod urabiania o podobnym poziomie zagrożenia geotechnicznego. Zaproponowano klasyfikację górotworu na podstawie właściwości wytrzymałościowych określanych rutynowo na etapie planowania kopalni. Klasyfikacja ta podzielona jest na kilka pod-etapów odpowiadającym etapom planowania kopalni, tak by uwzględnić zakres dostępnych na każdym etapie danych. Zastosowano kodowanie alfanumeryczne dla wskazania metody urabiania w oparciu o dane o zwięzłości skały i ryzyko zagrożenia geotechnicznego. Kodowanie alfanumeryczne zostało następnie rozszerzone dla identyfikacji operacji górniczych w ramach kategorii "Poziom zagrożenia geotechnicznego". Wskaźnik ten wykorzystywany jest jako wstępne narzędzie oceny ryzyka wystąpienia zagrożenia oraz klasyfikacji poziomu zagrożenia związanego z działalnością górniczą. Celem takiej klasyfikacji jest jej wykorzystanie jako wytycznych i uzasadnienia dla stosowania formalnych metod oceny ryzyka geotechnicznego.

Numerical Strength Analysis of a Complex, Steel Shell Structure/ Numeryczna Analiza Wytrzymałosciowa Pewnej Złożonej, Stalowej Konstrukcji Powłokowej

NASA Astrophysics Data System (ADS)

Burczynski, Grzegorz; Marcinowski, Jakub

2014-09-01

The paper deals with the numerical modelling of a complex, steel shell structure. The part under analysis is the upper segment of a steel pylon, which consists of several cylindrical shells and one conical segment. Particular parts of the structure are welded together. Geometrical and loading data calculations were performed for the particular material for both an ideally elastic case and an elasto-plastic case. The conclusion that the structural member analysed required strengthening were drawn on the basis of these results. The structural modification was proposed and additional calculations for this modified structure were also performed. Introduced additional shell elements locked the mechanism of plastic flow. The proposed modification can be treated as a possible strengthening concept. The whole analysis was performed by means of the ABAQUS system but some stages of calculations were also verified by the COSMOS/M system. Przedmiotem pracy jest numeryczne modelowanie pewnej bardzo złożonej, stalowej konstrukcji powłokowej. Analizowana szczegółowo czesc jest górnym fragmentem stalowego pylonu, na który składa sie kilka odcinków powłok cylindrycznych oraz jeden segment stożkowy. Te poszczególne fragmenty konstrukcji były ze soba połaczone spawaniem. Dla znanych parametrów materiałowych, geometrycznych i obciażeniowych wykonano obliczenia w zakresie idealnie spreżystym oraz w zakresie spreżystoplastycznym. Na podstawie tych obliczen wyciagnieto wniosek o koniecznosci wzmocnienia tej czesci pylonu. Zaproponowano istotna modyfikacje istniejacej konstrukcji i wykonano dla niej ponownie obliczenia. Wprowadzone dodatkowe elementy powłokowe zablokowały mechanizm plastycznego płyniecia. Zaproponowana modyfikacje można potraktowac jako jedna z możliwych koncepcji wzmocnienia konstrukcji. Wszystkie analizy numeryczne zostały wykonane za pomoca systemu ABAQUS. Pewne wybrane fragmenty obliczen były weryfikowane także z pomoca systemu COSMOS/M.

75 FR 71148 - Solicitation for a Cooperative Agreement-Production of Seven Live Satellite/Internet Broadcasts

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-22

... defined as training/ education transpiring between trainers and facilitators at one location and... NIC's distance learning administrator (DLA) on program design, program coordination, design and field... activities that support each broadcast. A minimum of one face-to-face planning session will be held for each...

The Influence of Drama on Elementary Students' Written Narratives and On-Task Behavior

ERIC Educational Resources Information Center

Anderson, Alida; Berry, Katherine A.

2014-01-01

Dramatic language arts integration (DLA) and conventional language arts (CLA) lessons were compared for their influence on third grade students' written narrative cohesion and on-task behavior in a self-contained, nonpublic elementary classroom. Participants included students (N = 14) with comorbid language-based learning disabilities (LD) and…

76 FR 76954 - Notice of Amendment No. 004 to the Solicitation for Cooperative Agreement Applications (SCAA...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-09

... Cooperative Agreement Applications (SCAA) Issued on July 7, 2010 AGENCY: Defense Logistics Agency, Department.... SUMMARY: The Defense Logistics Agency (DLA) executes the Department of Defense (DoD) Procurement Technical... applications will only be considered from entities proposing to provide service to an area that will not be...

77 FR 15361 - Notice of Amendment No. 001 to the Solicitation for Cooperative Agreement Applications (SCAA...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-15

... July 7, 2010 AGENCY: Defense Logistics Agency, DoD. ACTION: Amended solicitations for cost sharing cooperative agreement applications. SUMMARY: The Defense Logistics Agency (DLA) executes the Department of... be considered from entities proposing to provide service to an area that will not be covered by an...

5 CFR Appendix A to Part 582 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2011 CFR

2011-01-01

... Center, Office of General Counsel, Attention: Code L, P.O. Box 998002, Cleveland, OH 44199-8002, (216... Agency (DCAA) and the Defense Logistics Agency (DLA) who are employed outside the United States: See..., Bureau of Reclamation. Administrative Service Center, Department of the Interior, P.O. Box 272030, 7201...

5 CFR Appendix A to Part 582 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2013 CFR

2013-01-01

... Center, Office of General Counsel, Attention: Code L, P.O. Box 998002, Cleveland, OH 44199-8002, (216... Agency (DCAA) and the Defense Logistics Agency (DLA) who are employed outside the United States: See..., Bureau of Reclamation. Administrative Service Center, Department of the Interior, P.O. Box 272030, 7201...

5 CFR Appendix A to Part 582 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2012 CFR

2012-01-01

... Center, Office of General Counsel, Attention: Code L, P.O. Box 998002, Cleveland, OH 44199-8002, (216... Agency (DCAA) and the Defense Logistics Agency (DLA) who are employed outside the United States: See..., Bureau of Reclamation. Administrative Service Center, Department of the Interior, P.O. Box 272030, 7201...

5 CFR Appendix A to Part 582 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2010 CFR

2010-01-01

... Center, Office of General Counsel, Attention: Code L, P.O. Box 998002, Cleveland, OH 44199-8002, (216... Agency (DCAA) and the Defense Logistics Agency (DLA) who are employed outside the United States: See..., Bureau of Reclamation. Administrative Service Center, Department of the Interior, P.O. Box 272030, 7201...

5 CFR Appendix A to Part 582 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2014 CFR

2014-01-01

... Center, Office of General Counsel, Attention: Code L, P.O. Box 998002, Cleveland, OH 44199-8002, (216... Agency (DCAA) and the Defense Logistics Agency (DLA) who are employed outside the United States: See..., Bureau of Reclamation. Administrative Service Center, Department of the Interior, P.O. Box 272030, 7201...

Expeditionary Warfare Division Meeting (10th) Held in Panama City, Florida on 24-27 October 2005

DTIC Science & Technology

2005-10-01

Seabasing a TRANSCOM Perspective, by Captain Craig Galloway, USN, US Transportation Command, J5A DLA Afloat, by Col Jeff Hill, Chief, Distribution ... Management Division, Defense Logistics Agency Sustaining the Seabase a View…, by Mr. Nicholas Linkowitz, HQMC I&L (Code LPV) Sustaining the Sea Base

Tankering Fuel on U.S. Air Force Transport Aircraft: An Assessment of Cost Savings

DTIC Science & Technology

2015-01-01

2012, Fort Belvoir, Va., undated-c. As of September 29, 2014 : http://www.energy.dla.mil/library/Pages/Publications.aspx Federal Aviation...1978. ———, Water in Aviation Fuel, AC 20-125, November 12, 1985. Fregnani, Guerreiro, José Alexandre Tavares, Carlos Müller, and Anderson Ribeiro

76 FR 18750 - Ocean Renewable Power Company, LLC; Notice of Change in Docket Number

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 12680-003; Project No. 12711-003] Ocean Renewable Power Company, LLC; Notice of Change in Docket Number On July 24, 2009, Ocean Renewable Power Company, LLC (ORPC) filed a draft hydrokinetic pilot license application (DLA) for the...

Loglines. January-February 2014

DTIC Science & Technology

2014-02-01

potentially fewer than 300. When you cut up an MRAP, you get about $9,000 worth of scrap out of it, plus all the work that goes into it. But, when you...support when units depart Afghanistan. 2,546: Gallons of sparkling grape juice DLA Troop Support supplied to U.S. forces in Afghanistan for special

MHC variability supports dog domestication from a large number of wolves: high diversity in Asia.

PubMed

Niskanen, A K; Hagström, E; Lohi, H; Ruokonen, M; Esparza-Salas, R; Aspi, J; Savolainen, P

2013-01-01

The process of dog domestication is still somewhat unresolved. Earlier studies indicate that domestic dogs from all over the world have a common origin in Asia. So far, major histocompatibility complex (MHC) diversity has not been studied in detail in Asian dogs, although high levels of genetic diversity are expected at the domestication locality. We sequenced the second exon of the canine MHC gene DLA-DRB1 from 128 Asian dogs and compared our data with a previously published large data set of MHC alleles, mostly from European dogs. Our results show that Asian dogs have a higher MHC diversity than European dogs. We also estimated that there is only a small probability that new alleles have arisen by mutation since domestication. Based on the assumption that all of the currently known 102 DLA-DRB1 alleles come from the founding wolf population, we simulated the number of founding wolf individuals. Our simulations indicate an effective population size of at least 500 founding wolves, suggesting that the founding wolf population was large or that backcrossing has taken place.

Flat electron beam sources for DLA accelerators

DOE PAGES

Ody, A.; Musumeci, P.; Maxson, J.; ...

2016-10-26

In this study we discuss the application of the flat beam transform to generate beams suitable for injection into slab-symmetric dielectric laser-driven accelerators (DLAs). A study of the focusing requirements to keep the particles within the tight apertures characterizing these accelerators shows the benefits of employing ultralow beam emittances. The slab geometry of the many dielectric accelerating structures strongly favors the use of flat beams with large ratio between vertical and horizontal emittances. We employ particle tracking simulations to study the application of the flat beam transform for two injector designs, a DC non relativistic photogun and a 1.6 cellmore » S-band RF photoinjector, obtaining in both cases emittance ratios between the horizontal and vertical plane in excess of 100 in agreement with simple analytical estimates. The 4 MeV RF photoinjector study-case can be directly applied to the UCLA Pegasus beamline and shows normalized emittances down to < 3 nm in the vertical dimension for beam charges up to 20 fC, enabling a two-stage DLA experiment.« less

Isolation of circulating tumor cells from pancreatic cancer by automated filtration

PubMed Central

Brychta, Nora; Drosch, Michael; Driemel, Christiane; Fischer, Johannes C.; Neves, Rui P.; Esposito, Irene; Knoefel, Wolfram; Möhlendick, Birte; Hille, Claudia; Stresemann, Antje; Krahn, Thomas; Kassack, Matthias U.; Stoecklein, Nikolas H.; von Ahsen, Oliver

2017-01-01

It is now widely recognized that the isolation of circulating tumor cells based on cell surface markers might be hindered by variability in their protein expression. Especially in pancreatic cancer, isolation based only on EpCAM expression has produced very diverse results. Methods that are independent of surface markers and therefore independent of phenotypical changes in the circulating cells might increase CTC recovery also in pancreatic cancer. We compared an EpCAM-dependent (IsoFlux) and a size-dependent (automated Siemens Healthineers filtration device) isolation method for the enrichment of pancreatic cancer CTCs. The recovery rate of the filtration based approach is dramatically superior to the EpCAM-dependent approach especially for cells with low EpCAM-expression (filtration: 52%, EpCAM-dependent: 1%). As storage and shipment of clinical samples is important for centralized analyses, we also evaluated the use of frozen diagnostic leukapheresis (DLA) as source for isolating CTCs and subsequent genetic analysis such as KRAS mutation detection analysis. Using frozen DLA samples of pancreatic cancer patients we detected CTCs in 42% of the samples by automated filtration. PMID:29156783

Isolation of circulating tumor cells from pancreatic cancer by automated filtration.

PubMed

Brychta, Nora; Drosch, Michael; Driemel, Christiane; Fischer, Johannes C; Neves, Rui P; Esposito, Irene; Knoefel, Wolfram; Möhlendick, Birte; Hille, Claudia; Stresemann, Antje; Krahn, Thomas; Kassack, Matthias U; Stoecklein, Nikolas H; von Ahsen, Oliver

2017-10-17

It is now widely recognized that the isolation of circulating tumor cells based on cell surface markers might be hindered by variability in their protein expression. Especially in pancreatic cancer, isolation based only on EpCAM expression has produced very diverse results. Methods that are independent of surface markers and therefore independent of phenotypical changes in the circulating cells might increase CTC recovery also in pancreatic cancer. We compared an EpCAM-dependent (IsoFlux) and a size-dependent (automated Siemens Healthineers filtration device) isolation method for the enrichment of pancreatic cancer CTCs. The recovery rate of the filtration based approach is dramatically superior to the EpCAM-dependent approach especially for cells with low EpCAM-expression (filtration: 52%, EpCAM-dependent: 1%). As storage and shipment of clinical samples is important for centralized analyses, we also evaluated the use of frozen diagnostic leukapheresis (DLA) as source for isolating CTCs and subsequent genetic analysis such as KRAS mutation detection analysis. Using frozen DLA samples of pancreatic cancer patients we detected CTCs in 42% of the samples by automated filtration.

From "Sooo excited!!!" to "So proud": using language to study development.

PubMed

Kern, Margaret L; Eichstaedt, Johannes C; Schwartz, H Andrew; Park, Gregory; Ungar, Lyle H; Stillwell, David J; Kosinski, Michal; Dziurzynski, Lukasz; Seligman, Martin E P

2014-01-01

We introduce a new method, differential language analysis (DLA), for studying human development in which computational linguistics are used to analyze the big data available through online social media in light of psychological theory. Our open vocabulary DLA approach finds words, phrases, and topics that distinguish groups of people based on 1 or more characteristics. Using a data set of over 70,000 Facebook users, we identify how word and topic use vary as a function of age and compile cohort specific words and phrases into visual summaries that are face valid and intuitively meaningful. We demonstrate how this methodology can be used to test developmental hypotheses, using the aging positivity effect (Carstensen & Mikels, 2005) as an example. While in this study we focused primarily on common trends across age-related cohorts, the same methodology can be used to explore heterogeneity within developmental stages or to explore other characteristics that differentiate groups of people. Our comprehensive list of words and topics is available on our web site for deeper exploration by the research community. PsycINFO Database Record (c) 2014 APA, all rights reserved.

The effect of epsilon-caproyl/D,L-lactyl unit composition on the hydrolytic degradation of poly(D,L-lactide-ran-epsilon-caprolactone)-poly(ethylene glycol)-poly(D,L-lactide-ran-epsilon-caprolactone).

PubMed

Cho, Hanjin; An, Jeongho

2006-02-01

The degradation of P(DLAX-ran-CLY)-b-PEG-b-P(DLAX-ran-CLY)s ( P(DLAX-ran-CLY): Poly(D,L-lactide-ran-epsilon-caprolactone), PEG: Poly(ethylene glycol), X: D,L-lactyl unit fraction, Y: epsilon-caproyl unit fraction) is investigated. The fraction of DLA in the both end blocks is varied while the overall molecular weight and molecular weight of PEG are kept constant. DSC, XRD and GPC are employed to track the degradation process up to 200 days. Also the change in the surface and cross-sectional morphology is provided by SEM micro-photographs. The result of water absorption and weight loss characterization reveals that the incorporation of DLA in the polyester block could be an effective tool to facilitate degradation as well as water absorption. By tracking the change of molecular weight and polydispersity, chain scission and transport or removal of degraded product from the specimen were found to play a complex role in overall degradation.

THE ALFALFA H I ABSORPTION PILOT SURVEY: A WIDE-AREA BLIND DAMPED Ly{alpha} SYSTEM SURVEY OF THE LOCAL UNIVERSE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Darling, Jeremy; Macdonald, Erin P.; Haynes, Martha P.

2011-11-20

We present the results of a pilot survey for neutral hydrogen (H I) 21 cm absorption in the Arecibo Legacy Fast Arecibo L-Band Feed Array (ALFALFA) Survey. This project is a wide-area 'blind' search for H I absorption in the local universe, spanning -650 km s{sup -1} < cz < 17, 500 km s{sup -1} and covering 517.0 deg{sup 2} (7% of the full ALFALFA survey). The survey is sensitive to H I absorption lines stronger than 7.7 mJy (8983 radio sources) and is 90% complete for lines stronger than 11.0 mJy (7296 sources). The total redshift interval sensitive tomore » all damped Ly{alpha} (DLA) systems (N{sub H{sub i}}{>=}2 Multiplication-Sign 10{sup 20} cm{sup -2}) is {Delta}z = 7.0 (129 objects, assuming T{sub s} = 100 K and covering fraction unity); for super-DLAs (N{sub H{sub i}}{>=}2 Multiplication-Sign 10{sup 21} cm{sup -2}) it is {Delta}z = 128.2 (2353 objects). We re-detect the intrinsic H I absorption line in UGC 6081 but detect no intervening absorption line systems. We compute a 95% confidence upper limit on the column density frequency distribution function f(N{sub H{sub i}},X) spanning four orders of magnitude in column density, 10{sup 19} (T{sub s} /100 K) (1/f) cm{sup -2}

Design Pattern Mining Using Distributed Learning Automata and DNA Sequence Alignment

PubMed Central

Esmaeilpour, Mansour; Naderifar, Vahideh; Shukur, Zarina

2014-01-01

Context Over the last decade, design patterns have been used extensively to generate reusable solutions to frequently encountered problems in software engineering and object oriented programming. A design pattern is a repeatable software design solution that provides a template for solving various instances of a general problem. Objective This paper describes a new method for pattern mining, isolating design patterns and relationship between them; and a related tool, DLA-DNA for all implemented pattern and all projects used for evaluation. DLA-DNA achieves acceptable precision and recall instead of other evaluated tools based on distributed learning automata (DLA) and deoxyribonucleic acid (DNA) sequences alignment. Method The proposed method mines structural design patterns in the object oriented source code and extracts the strong and weak relationships between them, enabling analyzers and programmers to determine the dependency rate of each object, component, and other section of the code for parameter passing and modular programming. The proposed model can detect design patterns better that available other tools those are Pinot, PTIDEJ and DPJF; and the strengths of their relationships. Results The result demonstrate that whenever the source code is build standard and non-standard, based on the design patterns, then the result of the proposed method is near to DPJF and better that Pinot and PTIDEJ. The proposed model is tested on the several source codes and is compared with other related models and available tools those the results show the precision and recall of the proposed method, averagely 20% and 9.6% are more than Pinot, 27% and 31% are more than PTIDEJ and 3.3% and 2% are more than DPJF respectively. Conclusion The primary idea of the proposed method is organized in two following steps: the first step, elemental design patterns are identified, while at the second step, is composed to recognize actual design patterns. PMID:25243670

Structural features based genome-wide characterization and prediction of nucleosome organization

PubMed Central

2012-01-01

Background Nucleosome distribution along chromatin dictates genomic DNA accessibility and thus profoundly influences gene expression. However, the underlying mechanism of nucleosome formation remains elusive. Here, taking a structural perspective, we systematically explored nucleosome formation potential of genomic sequences and the effect on chromatin organization and gene expression in S. cerevisiae. Results We analyzed twelve structural features related to flexibility, curvature and energy of DNA sequences. The results showed that some structural features such as DNA denaturation, DNA-bending stiffness, Stacking energy, Z-DNA, Propeller twist and free energy, were highly correlated with in vitro and in vivo nucleosome occupancy. Specifically, they can be classified into two classes, one positively and the other negatively correlated with nucleosome occupancy. These two kinds of structural features facilitated nucleosome binding in centromere regions and repressed nucleosome formation in the promoter regions of protein-coding genes to mediate transcriptional regulation. Based on these analyses, we integrated all twelve structural features in a model to predict more accurately nucleosome occupancy in vivo than the existing methods that mainly depend on sequence compositional features. Furthermore, we developed a novel approach, named DLaNe, that located nucleosomes by detecting peaks of structural profiles, and built a meta predictor to integrate information from different structural features. As a comparison, we also constructed a hidden Markov model (HMM) to locate nucleosomes based on the profiles of these structural features. The result showed that the meta DLaNe and HMM-based method performed better than the existing methods, demonstrating the power of these structural features in predicting nucleosome positions. Conclusions Our analysis revealed that DNA structures significantly contribute to nucleosome organization and influence chromatin structure and gene expression regulation. The results indicated that our proposed methods are effective in predicting nucleosome occupancy and positions and that these structural features are highly predictive of nucleosome organization. The implementation of our DLaNe method based on structural features is available online. PMID:22449207

Problem of the Optical Model for Deuterons; ZAGADNIENIA MODELU OPTYCZNEGO DLA DEUTERONOW

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grotowski, K.

1963-01-01

Problems concerning parameters of the optical potential for deuterons are presented. Total cross-sections for the interaction of deuterons with nuclei were determined by the evaluation of the cross-sections for the emission of charged particles and neutrons. The angular distributions for the elastic scattering of deuterons were also measured, 47 references. (auth)

Loglines. September-October 2013

DTIC Science & Technology

2013-10-01

comes to new technologies that can improve product performance for our customers and reduce costs, storage and transportation requirements and...in. DLA Strategic Materials is partnering with academic institutions such as Penn State, Yale and MIT to research storage and transportation of...direct delivery contracting office, inventory and requirements division, and the transportation /tankers group, Domen said. Internal support is also

40 CFR Table 2 to Subpart Sssss of... - Operating Limits

Code of Federal Regulations, 2010 CFR

2010-07-01

... activity level of the catalyst at least every 12 months. 7. Each affected batch process unit For each batch... activity level of the catalyst at least every 12 months. 10. Each new kiln that is used to process clay... across the DLA at or above the minimum levels established during the most recent performance test; and b...

40 CFR Table 2 to Subpart Sssss of... - Operating Limits

Code of Federal Regulations, 2011 CFR

2011-07-01

... activity level of the catalyst at least every 12 months. 7. Each affected batch process unit For each batch... activity level of the catalyst at least every 12 months. 10. Each new kiln that is used to process clay... across the DLA at or above the minimum levels established during the most recent performance test; and b...

78 FR 64493 - Juneau Hydropower, Inc.; Notice of Subsequent Draft License Application (DLA) and Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-29

..., Business Manager, Juneau Hydropower, Inc., P.O. Box 22775, Juneau, AK 99802; 907-789-2775, email: duff... information at the end of your comments. For assistance, please contact FERC Online Support at FERCOnline... number field to access the document. For assistance, contact FERC Online Support. You may also register...

Fuel Price Effects on Readiness

DTIC Science & Technology

2014-05-01

Wide Fuel Management 1. DLA’s Role DLA-E has the mission of acquiring, storing, selling, and distributing energy including petroleum, natural gas ...energy, and installations also use energy in the form of electricity (11 percent), natural gas (8 percent), and coal (2 percent). See Schwartz, Blakely...have also excluded liquefied propane gas (LPG), from this study. 10 through four IDIQ

Exploring the Impact of Students' Learning Approach on Collaborative Group Modeling of Blood Circulation

ERIC Educational Resources Information Center

Lee, Shinyoung; Kang, Eunhee; Kim, Heui-Baik

2015-01-01

This study aimed to explore the effect on group dynamics of statements associated with deep learning approaches (DLA) and their contribution to cognitive collaboration and model development during group modeling of blood circulation. A group was selected for an in-depth analysis of collaborative group modeling. This group constructed a model in a…

77 FR 20354 - Proposed Information Collection; Comment Request; Quarterly Survey of Plant Capacity Utilization

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-04

... hours worked. The primary users of these data will be the Federal Reserve Board (FRB) and the Defense Logistics Agency (DLA). The FRB will use these data in several ways. First, the capital workweek data will...). Second, the workweek data will be used to improve the projections of labor productivity that are used to...

Demand Forecasting: DLA’S Aviation Supply Chain High Value Products

DTIC Science & Technology

2015-04-09

program at USS CONSTELLATION (CV 64), San Diego CA LCDR Carlos Lopez Education  MBA in Supply Chain Management, Naval Postgraduate School  BS in...Exponential Smoothing Forecasts ............... 118 xv Figure 80. NIIN 01-463-4340 Seasonal Exponential Smoothing Forecast .............. 119 Figure...5310 Seasonal Exponential Smoothing ............................ 142 Figure 102. NIIN 01-507-5310 12-Month Forecast Simulation

32 CFR Appendix A to Part 1292 - Section 21 of the Internal Security Act of 1950

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Section 21 of the Internal Security Act of 1950 A Appendix A to Part 1292 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES Pt. 1292, App. A Appendix A to Part...

Additive Manufacturing: Which DLA-Managed Legacy Parts are Potential AM Candidates

DTIC Science & Technology

2016-07-01

william.t.veney.civ@mail.mil Mr. Scot Seitz Army/G4 717-770-4304 scot.s.seitz.civ@mail.mil Mr. Stephen Luckowski Army/RDECOM 973-724-3100...stephen.l.luckowski.civ@mail.mil Maj. Eric Kirchner Marine Corps/I&L 571-256-7105 eric.kirchner@usmc.mil Capt. Christopher Wood Marine Corps/I&L 571-256-2740

32 CFR Appendix A to Part 1292 - Section 21 of the Internal Security Act of 1950

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Section 21 of the Internal Security Act of 1950 A Appendix A to Part 1292 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES Pt. 1292, App. A Appendix A to Part...

32 CFR Appendix A to Part 1292 - Section 21 of the Internal Security Act of 1950

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Section 21 of the Internal Security Act of 1950 A Appendix A to Part 1292 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES Pt. 1292, App. A Appendix A to Part...

32 CFR Appendix A to Part 1292 - Section 21 of the Internal Security Act of 1950

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Section 21 of the Internal Security Act of 1950 A Appendix A to Part 1292 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES Pt. 1292, App. A Appendix A to Part...

32 CFR Appendix A to Part 1292 - Section 21 of the Internal Security Act of 1950

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Section 21 of the Internal Security Act of 1950 A Appendix A to Part 1292 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES Pt. 1292, App. A Appendix A to Part...

Baseline Suitability Analysis

DTIC Science & Technology

2013-07-18

VA) • DFAS • Human Resources - HR Shared Services (Indianapolis, IN) • Personnel Security - HR Shared Services (Indianapolis, IN) DHRA...Security (Camp Lejeune) No Yes Yes AAFES Human Resources No No No Force Protection Yes Yes Yes DFAS Human Resources - HR Shared Services No...No No Personnel Security - HR Shared Services Yes Yes Yes DLA Human Resources No No Yes Personnel Security Yes Yes Yes DoDEA Human

ICP Corporate Customer Assessment - Sampling Plan

DTIC Science & Technology

1995-07-01

CORPORATE CUSTOMER ASSESSMENT - SAMPLING PLAN JULY 1995 Lead Analyst: Lieutenant Commander William J. Wilkinson, USN Associate Analyst: Mr. Henry J...project developed a plan for conducting recurring surveys of Defense Logistics Agency customers , in support of the DLA Corporate Customer Assessment...Team. The primary product was a sampling plan, including stratification of customers by Military Service or Federal Agency and by commodity purchased

Independent Review of the Defense Logistics Agencys Roles and Missions

DTIC Science & Technology

2014-12-01

remaining wholesale consumables missions of tires, packaged petroleum, oils , and lubricants, and gases and cylinders were transferred from the...housekeeping supplies and equipment. Class III: Petroleum, oils , and lubricants. Class IV: Construction materials. Class V: Ammunition. Class VI...own appropriated funds that are deposited 9 The Construction and Equipment program within DLA Troop Support provides some Class VII non- weapons

Deep linear autoencoder and patch clustering-based unified one-dimensional coding of image and video

NASA Astrophysics Data System (ADS)

Li, Honggui

2017-09-01

This paper proposes a unified one-dimensional (1-D) coding framework of image and video, which depends on deep learning neural network and image patch clustering. First, an improved K-means clustering algorithm for image patches is employed to obtain the compact inputs of deep artificial neural network. Second, for the purpose of best reconstructing original image patches, deep linear autoencoder (DLA), a linear version of the classical deep nonlinear autoencoder, is introduced to achieve the 1-D representation of image blocks. Under the circumstances of 1-D representation, DLA is capable of attaining zero reconstruction error, which is impossible for the classical nonlinear dimensionality reduction methods. Third, a unified 1-D coding infrastructure for image, intraframe, interframe, multiview video, three-dimensional (3-D) video, and multiview 3-D video is built by incorporating different categories of videos into the inputs of patch clustering algorithm. Finally, it is shown in the results of simulation experiments that the proposed methods can simultaneously gain higher compression ratio and peak signal-to-noise ratio than those of the state-of-the-art methods in the situation of low bitrate transmission.

A project based on multi-configuration Dirac-Fock calculations for plasma spectroscopy

NASA Astrophysics Data System (ADS)

Comet, M.; Pain, J.-C.; Gilleron, F.; Piron, R.

2017-09-01

We present a project dedicated to hot plasma spectroscopy based on a Multi-Configuration Dirac-Fock (MCDF) code, initially developed by J. Bruneau. The code is briefly described and the use of the transition state method for plasma spectroscopy is detailed. Then an opacity code for local-thermodynamic-equilibrium plasmas using MCDF data, named OPAMCDF, is presented. Transition arrays for which the number of lines is too large to be handled in a Detailed Line Accounting (DLA) calculation can be modeled within the Partially Resolved Transition Array method or using the Unresolved Transition Arrays formalism in jj-coupling. An improvement of the original Partially Resolved Transition Array method is presented which gives a better agreement with DLA computations. Comparisons with some absorption and emission experimental spectra are shown. Finally, the capability of the MCDF code to compute atomic data required for collisional-radiative modeling of plasma at non local thermodynamic equilibrium is illustrated. In addition to photoexcitation, this code can be used to calculate photoionization, electron impact excitation and ionization cross-sections as well as autoionization rates in the Distorted-Wave or Close Coupling approximations. Comparisons with cross-sections and rates available in the literature are discussed.

Computer Simulation Elucidates Yeast Flocculation and Sedimentation for Efficient Industrial Fermentation.

PubMed

Liu, Chen-Guang; Li, Zhi-Yang; Hao, Yue; Xia, Juan; Bai, Feng-Wu; Mehmood, Muhammad Aamer

2018-05-01

Flocculation plays an important role in the immobilized fermentation of biofuels and biochemicals. It is essential to understand the flocculation phenomenon at physical and molecular scale; however, flocs cannot be studied directly due to fragile nature. Hence, the present study is focused on the morphological specificities of yeast flocs formation and sedimentation via the computer simulation by a single floc growth model, based on Diffusion-Limited Aggregation (DLA) model. The impact of shear force, adsorption, and cell propagation on porosity and floc size is systematically illustrated. Strong shear force and weak adsorption reduced floc size but have little impact on porosity. Besides, cell propagation concreted the compactness of flocs enabling them to gain a larger size. Later, a multiple flocs growth model is developed to explain sedimentation at various initial floc sizes. Both models exhibited qualitative agreements with available experimental data. By regulating the operation constraints during fermentation, the present study will lead to finding optimal conditions to control the floc size distribution for efficient fermentation and harvesting. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Fractal Viscous Fingering in Fracture Networks

NASA Astrophysics Data System (ADS)

Boyle, E.; Sams, W.; Ferer, M.; Smith, D. H.

2007-12-01

We have used two very different physical models and computer codes to study miscible injection of a low- viscosity fluid into a simple fracture network, where it displaces a much-more viscous "defending" fluid through "rock" that is otherwise impermeable. The one code (NETfLow) is a standard pore level model, originally intended to treat laboratory-scale experiments; it assumes negligible mixing of the two fluids. The other code (NFFLOW) was written to treat reservoir-scale engineering problems; It explicitly treats the flow through the fractures and allows for significant mixing of the fluids at the interface. Both codes treat the fractures as parallel plates, of different effective apertures. Results are presented for the composition profiles from both codes. Independent of the degree of fluid-mixing, the profiles from both models have a functional form identical to that for fractal viscous fingering (i.e., diffusion limited aggregation, DLA). The two codes that solve the equations for different models gave similar results; together they suggest that the injection of a low-viscosity fluid into large- scale fracture networks may be much more significantly affected by fractal fingering than previously illustrated.

[Franciszek Leopold Lafontaine (1756-1812) and his work on catarrh].

PubMed

Kierzek, Andrzej

2010-01-01

The professional and scientific activities of Leopold Lafontaine (1756-1812), an eminent military surgeon, the chief army surgeon in the Grand Duchy of Warsaw are presented in full particular. He was a editor-in-chief and publisher of the first Polish medical periodical "Dziennik Zdrowia dla Wszystkich Stanów" ("The Journal of Health for all the Estates"). His work on catarrh is discussed widely.

Regional Disease Vector Ecology Profile: The Koreas

DTIC Science & Technology

2015-01-01

Lymantriidae): The larvae, pupae and adults of E. flava are covered with hairs that cause dermatitis (papulourticarial reaction) when they contact ...Information Services Division at (301) 295-8310/7476, DSN 295- 8310/7476 or the AFPMB Webmaster, http://www.afpmb.org/ contact . Current Information: Current...timely manner. For insect repellents, pesticides, pesticide application equipment, PPMs (bed nets, head nets, etc.) and respirators contact the DLA

Congressional Liaison Offices of Selected Federal Agencies

DTIC Science & Technology

2010-09-03

Offices of Selected Federal Agencies Congressional Research Service 1 Legislative Branch Congressional Budget Office Edward “Sandy” Davis...VA 22060-6221 Tel: (703) 767-5264 Fax: (703) 767-6312 http://www.dla.mil/ Defense Security Cooperation Agency Vanessa Murray Director...Fax: (202) 685-6077 http://www.marines.mil/units/hqmc/Pages/ default.aspx For Senate offices: Lt. Col. Harold R. Van Opdorp U.S.M.C. Deputy

Loglines. September - October 2010

DTIC Science & Technology

2010-10-01

of community among our global workforce and a single-agency environment that shows warfighters just who DLA is and what we provide to them... apparel and electronics to prescription drugs. Military equipment is no exception, and the consequence of malfunctioning gear can be dangerous to...water might meet Deer Park’s criteria, it’s a misrepresentation of the Deer Park brand ,” he explained. “The question then becomes ‘Who

Total Quality Management Implementation Plan: Defense Depot, Ogden

DTIC Science & Technology

1989-07-01

NUMBERS Total Quality Management Implementation Plan Defense Depot Ogden 6. AUTHOR(S) 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING...PAGES TQM (Total Quality Management ), Continuous Process Improvement, Depot Operations, Process Action Teams 16. PRICE CODE 17. SECURITY...034 A Message From The Commander On Total Quality Management i fully support the DLA aoproacii to Total Quality Management . As stated by General

LogLines. July-August 2009

DTIC Science & Technology

2009-08-01

Center. The Richmond supply center is using the new Sales and Operations Planning Process, known as S & OP and initiated by DLA Director Navy Vice...Adm. Alan Thompson in September, to facilitate strategic decisionmaking on the project, officials said. S & OP involves balancing the needs of...projects under the S & OP process involve getting 530 stock items on expedited contracts or ac- celerated purchases, and establishing a six-month

Defense Logistics Agency Green Products / Hazardous Minimization Warfighter Team: Helping the Warfighter Become Green!

DTIC Science & Technology

2010-06-01

Online Shopping Tool • Web self-service capability for the DOD • Sells both finished goods and services • Supports contracts written by DLA, GSA...month and over 750K items of content a month • FY08 Total Sales $835M; Green Sales $7.3M 11 DOD EMALL DOD’s Online Shopping Tool 1st Choice Support for

Defense Energy Support Center Fact Book, Fiscal Year 1999, Twenty-Second Edition

DTIC Science & Technology

1999-01-01

numbers SOURCE: FACILITIES AND DISTRIBUTION MANAGEMENT COMMODITY BUSINESS UNIT 11 OCONUS COCO 10 8,717,850...GOCO 7 1,518,905 SOURCE: FACILITIES AND DISTRIBUTION MANAGEMENT COMMODITY BUSINESS UNIT DLA MANAGED STORAGE...FY 95 FY 96 FY 97 FY 98 FY 99 SOURCE: FACILITIES AND DISTRIBUTION MANAGEMENT COMMODITY BUSINESS UNIT 13 0 20 40 60 80 100 120 140 160 180 200 220

Loglines. March - April 2012

DTIC Science & Technology

2012-04-01

greener and even more effective and efficient. “We have a hard-working team,” said James Reed, DLA’s Hazardous Minimization Program manager...2012 Sailors maneuver an experimental riverine command boat powered by a blend of algae- and petroleum-based fuel during an alternative fuels...of alternative fuels throughout the military. — Photo by Navy Petty Ofcer 2nd Class Josue L. Escobosa 18 www.dla.mil Determining the

DLA Energy Biofuel Feedstock Metrics Study

DTIC Science & Technology

2012-12-11

mission is to “provide the Depart- ment of Defense [DoD] and other government agencies with comprehensive ener- gy solutions in the most effective and...strategic imperative to consider energy security and climate change because of their potential effect on national security and mission readiness.8 For...mobility fuel costs have an adverse effect on military service programs and capa- bilities, particularly when combined with a tough appropriations

Loglines. March-April 2013

DTIC Science & Technology

2013-04-01

assistant commandant for engineering and logistics, said at the review. Rabago noted that over the years, he has seen the benefit of doing...place, they’re helping shape and determine the requirements, which is more of a partnership.” This expanded partnership benefits the Coast Guard...by freeing up resources for core missions and increasing logistics efficiency, but it also benefits DLA by expanding the agency’s customer base

Strategic Material Supply Mitigation Initiatives within DLA - Strategic Materials

DTIC Science & Technology

2012-05-24

8217 ••• " ,,, . .. ~· ,, " )!~ ·; Jl·m " ’ ’ "’ "N "’ ... "’ •• "’ "’ "’ "’ "’ ’" "’ "’ "’ ... Fr Ra Lr Rf Db Sg Bh Hs Mt Uun Uuu Uub Uuq Uuh Uuo """’~ Rll:llum

Curcumin-albumin conjugates as an effective anti-cancer agent with immunomodulatory properties.

PubMed

Aravind, S R; Krishnan, Lissy K

2016-05-01

Curcumin (diferuloylmethane) is an active ingredient in turmeric (Curcuma longa) with anti-inflammatory, antioxidant, chemopreventive, chemosensitization, and radiosensitization properties. Conjugation of curcumin (Curc) to albumin (Alb) has been found to increase the aqueous solubility of the drug. The current study aimed to prove the safe use of the Curc-Alb conjugate in animals and to demonstrate that it retains drug action both in vitro and in vivo. Dalton's lymphoma ascites (DLA) cell viability was inhibited by the Curc-Alb conjugate in a dose dependent manner in vitro, as evidenced by the MTT assay. Administration of up to 11.4 mg of conjugated curcumin per kg body weight to healthy animals was non-toxic both in terms of lethality and weight loss. Histological analysis of vital organs (kidney, liver and spleen) also did not show toxic effects. Favorable immuno-modulatory activity was observed after continuous administration of sub-acute doses of the conjugate which caused increase in total leukocyte count, platelet count, and viable cell count in bone marrow, and enhanced proliferation of lymphocyte in vitro upon culture. In vivo studies in the DLA tumor model in mice demonstrated that conjugated drug induces tumor reduction and prevention. Significant tumor reduction was observed when the Curc-Alb conjugate was administered intraperitoneally in DLA-induced mice after 1 day (prevention therapy) and 7 days (reduction therapy) of tumor induction. There was significant reduction in both tumor volume and tumor cell numbers in the treated animals as well as a marked increase in their mean survival time and percent increase in life span. The effect was greater when the conjugate was administered soon after inducing the tumor as compared to when treatment was started after allowing tumor to grow for 7 days. Thus, the results of the present study suggest that curcumin albumin conjugate has immunomodulatory and tumor growth inhibition properties. The study postulates the drug form has the potential to be used as an anticancer agent in affected human subjects. Copyright © 2016 Elsevier B.V. All rights reserved.

The Neutral Hydrogen Cosmological Mass Density at z = 5

NASA Astrophysics Data System (ADS)

Crighton, Neil H. M.; Murphy, Michael T.; Prochaska, J. Xavier; Worseck, Gábor; Rafelski, Marc; Becker, George D.; Ellison, Sara L.; Fumagalli, Michele; Lopez, Sebastian; Meiksin, Avery; O'Meara, John M.

2017-03-01

We present the largest homogeneous survey of redshift > 4.4 damped Lyα systems (DLAs) using the spectra of 163 quasars that comprise the Giant Gemini GMOS (GGG) survey. With this survey we make the most precise high-redshift measurement of the cosmological mass density of neutral hydrogen, ΩHI. After correcting for systematic effects using a combination of mock and higher-resolution spectra, we find ΩHI= 0.98+0.20 -0.18 × 10-3 at = 4.9, assuming a 20% contribution from lower column density systems below the DLA threshold. By comparing to literature measurements at lower redshifts, we show that ΩHI can be described by the functional form ΩHI(z) ~ (1 + z)0.4. This gradual decrease from z = 5 to 0 suggests that in the galaxies which dominate the cosmic star formation rate, Hi is a transitory gas phase fuelling star formation which must be continually replenished by more highly-ionized gas from the intergalactic medium, and from recycled galactic winds.

Defense Logistics Agency’s Warstopper Program

DTIC Science & Technology

2007-08-15

chamber. DLA decided to fund the construction of an additional Nesatron chamber with the option to sell it to the contractor at fair market value at...stored for contingencies. Without the Warstopper investment, the Services would have to build and stock their entire wartime requirement over a 2...Contract Number Date of the Contract Item Estimated Total Value ($ thousands) Warstopper FY 2005 Value ($ thousands) 1 SP0441-05-D-1652 Sept

Loglines. March-April 2014

DTIC Science & Technology

2014-04-01

engine mechanic, selects a compressor blade to install in the core module of an F-16 jet engine. DLA Aviation has partnered with Air Force customers to...Support 9 Supporting the Fleet 14 Air Force Support 18 Beyond the Military Services 22 SERVICE TEAMS Side-by-Side Support Chemical Management Services...Marine Corps ordnance technicians load a missile at Kunsan Air Base, South Korea. Service members from the different military branches often work

Defense Standardization Program Journal. April/September 2012

DTIC Science & Technology

2012-01-01

were magnified. In 1905, a committee of the National Fire Protection Association established a national standard for the diameter and threads per inch...for fire hydrants and hose couplings. The standard specifies that fire hydrants have 2.5-inch hose connections with 7.5 threads per inch and that...dsp.dla.mil I Field of view, lens material haze, luminous transmittance, and lens abrasion resistance (APR) I Communications (APR) I Fogging (APR

Sourcing and Global Distribution of Medical Supplies

DTIC Science & Technology

2014-01-01

dots in this figure represent OCONUS MTFs and the yellow star icons indicate locations of the OCONUS theater lead agents for medical materiel (TLAMMs... Symbol Definition AFMOA Air Force Medical Operations Agency AMC Air Mobility Command APS Army prepositioned stock Cat A Category A CJCS chairman of...provide medical materiel to military units. DLA has enacted PV and other contracts to support all military units that make it possible for units around

Loglines. July-August 2013

DTIC Science & Technology

2013-08-01

activities worldwide and industry customers of DLA. Contents of this publication are not necessarily the official views of, or endorsed by, the U.S...100 million for three months straight June • MRAP Stock Optimization Team established to maintain industrial readiness between the joint program ...SUBTITLE Loglines. July-August 2013 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK

Loglines. November - December 2011

DTIC Science & Technology

2011-12-01

We started ... with a complete review of building production,” said Marcel Baril , the team’s supervisor. His team inventoried all the parts it...on] them with any problems or concerns that may arise,” he said. Baril said the team’s accomplishments came in part from efforts to educate... Baril said, customers began notifying DLA Aviation in advance of their parts requirements, and his team was able to forecast those demands and

Finding Information in (Very Large) Digital Libraries: A Deep Log Approach to Determining Differences in Use According to Method of Access

ERIC Educational Resources Information Center

Nicholas, David; Huntington, Paul; Jamali, Hamid R.; Tenopir, Carol

2006-01-01

This report presents the early findings of an exploratory deep log analysis (DLA) of journal usage on OhioLINK, reporting on the information seeking methods of users. Compared to the users who sought information by browsing journals, those who conducted searches to find information and articles tended to record longer session times and viewed more…

Dual Management of Commercially Available Items - Information and Imaging Solutions.

DTIC Science & Technology

1998-06-03

Pentagon, Washington, D.C. 20301-1900. The identity of each writer and caller is fully protected. Acronyms DISC Defense Industrial Supply Center DLA...Defense Logistics Agency GSA General Services Administration JWOD Javits-Wagner-O’Day NIB National Industries for the Blind f INSPECTOR GENERAL...Defense Industrial Supply Center issued a solicitation to establish a prime vendor for its office solutions initiative. An amendment to the solicitation

Feasibility of Department of Defense Used Lubricating Oil Re-refining.

DTIC Science & Technology

1983-12-01

greater product selectivity (increasing cost effec- tiveness by tailoring the process to meet market demand ). In addition most processes have high yields...However, several issues were surfaced. The question of who in DLA is responsible for the administra- tion of a re-refining program must be resolved...Both the Property Disposal and Supply groups have a role. The Disposal group now has responsibility for .1%- iv -. d

Transfer of Department of Defense Managed Sustainment Programs in Iraq to Department of State Control

DTIC Science & Technology

2013-05-22

responsible for conducting Reception , Staging, Onward movement, and Integration of personnel and equipment, the distribution management of supplies...temperature refrigerated containers or leased refrigerated containers on semi- trailers . Class III Distribution As the DoD executive agent, DLA is...quantitative approach involves the investigation of a human or social problem, and tests the theory based on the collection of variables, numerically

DRMS World, April/May 2007

DTIC Science & Technology

2007-05-01

DEFENSE REUTILIZATION AND MARKETING SERVICE Visit ourWeb site at www.dla.milldrms April/May 2007 Every day is Earth Dayat DRMS Environmental...reutilization of track shoes for tanks (see story on page 12) Defense Reutilization and Marketing Service D oing it fight Our DRMS Vision DoD ’s Provider...firefighters wear red suspenders? Marketing Service, a field activity of the implements To hold their pants up. Defense Logistics Agency. Contents of

Vertical Alignment of Single-Walled Carbon Nanotubes on Nanostructure Fabricated by Atomic Force Microscope

DTIC Science & Technology

2007-03-30

Langmuir - Blodgett and self-assembly methods, WNTs are patterned selectively onto various substrates [3,4]. hou et al. assembled SWNTs into aligned...dispersion usually decreases with increasing ionic concentration, it is suggested that chloride ions are produced by dissociating from acid chloride groups...patterns can be attributed to the Marangoni effect and diffusion-limited aggregation (DLA) in the liquid film during droplet evaporation t different

Loglines. May - June 2010

DTIC Science & Technology

2010-06-01

able to get construction materials, food and spare parts into a land-locked country . More than 80 percent of the containers shipped through this...procurement management at DLA Oklahoma City, has developed a strategic roadmap for DLR decision-makers. “Trying to get our arms around all the contracts...currently in place and develop - ing a comprehensive approach to future support has been challenging,” Yort said. Transferring procurement of DLRs to

Loglines. September - October 2011

DTIC Science & Technology

2011-10-01

Services Region Los Angeles is responsible for the design, property and quality assurance of NASA’s Apollo- Soyuz space project, the first joint flight of...Sherman began his career with the organization that year as a management intern . He worked in the customer service departments of the Philadelphia and...the use of online documents and services . Sherman, that management intern in 1979, is now the director of DLA Document Services . He has been with

Defense Standardization Program Journal. January-March 2012

DTIC Science & Technology

2012-03-01

tanks and voids with solvent-based epoxy coatings, ap- plied with varying levels of process control. Because the coatings tended to fail initially at...solids (UHS) epoxy resins and contained no added solvent. In addition, the coat- dsp.dla.mil ings contained thixotropes to counter the tendency of...standardized materials, using universal application processes, to all ballast tanks, fuel tanks, and voids, on all Navy ship classes, including submarines

Department of Defense Annual Statement of Assurance, Volume II for Fiscal Year 1996.

DTIC Science & Technology

1996-12-01

FY 1996. US Army Audit Agency (USAAA) conducted a multilocation audit of contract security requirements at the request of the US Army Contracting...corrective action(s) are certified by the responsible components upon completion and reviewed through on-site verification, subsequent audit . inspection...requirement for processing Navy pricing inquiries received by DLA inventory control points. 9/97 Verification: Subsequent on-site verification. audit

HISTOCOMPATIBILITY STUDIES IN A CLOSELY BRED COLONY OF DOGS

PubMed Central

Rapaport, F. T.; Watanabe, K.; Cannon, F. D.; Mollen, N.; Blumenstock, D.; Ferrebee, J. W.

1972-01-01

17 Cooperstown beagles of known DL-A genotypes were exposed to supralethal total body irradiation and received a bone marrow allograft from a DL-A-identical donor; 11 littermate and 6 nonlittermate donor-recipient pairs were studied. The recipients are surviving uneventfully for 315, 364, 424, 440, 531, 531, 584, 605, 625, 635, and 649 days in the littermate group and for 211, 279, 280, 368, 479, and 480 days in the nonlittermate group. The radiation chimeras underwent bilateral nephrectomy and received a kidney allograft obtained from their respective marrow donor within 43–120 days after bone marrow transplantation. The renal allografts are surviving for 191, 200, 221, 234, 313, 349, 361, 377, 378, 405, 441, 444, 482, 557, 580, 581, and 586 days, respectively. 12 of 13 skin allografts obtained from the marrow donor are at present surviving in the recipients for 107, 110, 110, 110, 116, 122, 128, 143, 143, 162, 178, and 199 days, respectively; one graft was rejected at 84 days. In contrast, the radiation chimeras rejected 25 skin allografts obtained from DL-A-incompatible donors within 10.5–21 days (MST = 15.2 days). Skin transplants obtained from DL-A-identical siblings of the bone marrow donors were rejected within 20–36 days (MST = 25.8 days) in recipients of bone marrow cells obtained from littermate donors. Recipients of nonlittermate bone marrow transplants accorded such allografts a prolonged survival time of 27–76 days (MST = 56.2 days). Prospective selection of genotypically DL-A-identical donor-recipient pairs results in the regularly reproducible long-term survival of bone marrow allografts. The radiation chimeras produced in this manner have developed a donor-specific state of unresponsiveness to kidney and skin allografts. The results are consistent with the existence in the canine species of at least three closely linked genetic systems relevant to transplantation, including DL-A, MLC, and a possible bone marrow transplantation locus. PMID:4404277

CO-dark molecular gas at high redshift: very large H2 content and high pressure in a low-metallicity damped Lyman alpha system

NASA Astrophysics Data System (ADS)

Balashev, S. A.; Noterdaeme, P.; Rahmani, H.; Klimenko, V. V.; Ledoux, C.; Petitjean, P.; Srianand, R.; Ivanchik, A. V.; Varshalovich, D. A.

2017-09-01

We present a detailed analysis of an H2-rich, extremely strong intervening damped Ly α absorption system (DLA) at zabs = 2.786 towards the quasar J 0843+0221, observed with the Ultraviolet and Visual Echelle Spectrograph on the Very Large Telescope. The total column density of molecular (resp. atomic) hydrogen is log N(H2) = 21.21 ± 0.02 (resp. log N(H I) = 21.82 ± 0.11), making it to be the first case in quasar absorption line studies with H2 column density as high as what is seen in 13CO-selected clouds in the Milky Way. We find that this system has one of the lowest metallicity detected among H2-bearing DLAs, with [Zn/H] = -1.52^{+0.08}_{-0.10}. This can be the reason for the marked differences compared to systems with similar H2 column densities in the local Universe: (I) the kinetic temperature, T ˜ 120 K, derived from the J = 0, 1 H2 rotational levels is at least twice higher than expected; (II) there is little dust extinction with AV < 0.1; (III) no CO molecules are detected, putting a constraint on the XCO factor XCO > 2 × 1023 cm-2/(km s-1 K), in the very low metallicity gas. Low CO and high H2 contents indicate that this system represents 'CO-dark/faint' gas. We investigate the physical conditions in the H2-bearing gas using the fine-structure levels of C I, C II, Si II and the rotational levels of HD and H2. We find the number density to be about n ˜ 260-380 cm-3, implying a high thermal pressure of 3-5 × 104 cm-3 K. We further identify a trend of increasing pressure with increasing total hydrogen column density. This independently supports the suggestion that extremely strong DLAs (with log N(H) ˜22) probe high-z galaxies at low impact parameters.

Lick optical spectra of quasar HS 1946+7658 at 10 kilometers per second resolution Lyman-alpha forest and metal absorption systems

NASA Technical Reports Server (NTRS)

Fan, Xiao-Ming; Tytler, David

1994-01-01

We present optical spectra of the most luminous known quasi stellar object (QSO) HS 1946+7658 (z(sub em) = 3.051). Our spectra have both full wavelength coverage, 3240-10570 A, and in selected regions, either high signal-to-noise ratio, SNR approximately equals 40-100, or unusually high approximately 10 km/sec resolution, and in parts of the Ly alpha forest and to the red of Ly alpha emission they are among the best published. We find 113 Ly alpha systems and six metal-line systems, three of which are new. The metal systems at z(sub abs) = 2.844 and 3.050 have complex velocity structure with four and three prominent components, respectively. We find that the system at z(sub abs) = 2.844 is a damped Ly alpha absorption (DLA) system, with a neutral hydrogen column density of log N(H I) = 20.2 +/- 0.4, and it is the cause of the Lyman limit break at lambda approximately equals 3520 A. We believe that most of the H I column density in this system is in z(sub abs) = 2.8443 component which shows the strongest low-ionization absorption lines. The metal abundance in the gas phase of the system is (M/H) approximately equals -2.6 +/- 0.3, with a best estimate of (M/H) = -2.8, with ionizaion parameter log gamma = -2.75, from a photoionization model. The ratios of the logarithmic abundances of C, O, Al, and Si are all within a factor of 2 of solar, which is important for two reasons. First, we believe that the gas abundances which we measure are close to the total abundances, because the ratio of aluminum to other elements is near cosmic, and Al is a refractory element which depletes very readily like chromium, in the interstellar medium. Second, we do not see the enhancement of O with respect to C of (O/C) approximately equals 0.5-0.9 reported in three partial Lyman limit systems by Reimers et al. (1992) and Vogel & Reimers (1993); we measure (O/C) = -0.06 for observed ions and (O/C) approximately equals 0.2 after ionization corrections, which is consistent with solar abundances. We see C II*(lambda 1335) offset by 15 km/sec with respect to C II(lambda 1334), presumably because the gas density varies from 2 to 8 cm(exp -3) with changing velocity in the DLA system. These densities imply that the damped component is 6-25 pc thick, which is reasonable for a single cloud in a cold spiral disk. They also imply that the cloud is relatively highly ionized with more C III than C II, more O III than O I, and log N(H I) = 20.72, which is 3 times the H I column. The system at z(abs) = 1.7382 is also believed to be damped with N(H I) approximately equals 10(exp 21) cm(exp -2), because we see Cr II, but its Ly alpha line will never be seen because it is below the Lyman limit of the other DLA system. We see a 2.6 sigma lack of Ly alpha forest lines well away from the QSO redshift, which may be a chance fluctuation. We also see a correlation between column density N(H I) and Doppler parameter b for 96 unsaturated Ly Alpha forest absorption lines, and although this correlation persists in the 36 Ly alpha lines which lie in regions where the SNR approximately equals 8-16, we agree with Rauch et al. (1993) that it is probably a bogus effect of low supernova remnant (SNR). The same applies to lines with very low b values: in regions where SNR less than or equal to 8 we see many Ly alpha lines which appear to have 10 less than or equal to b less than or equal to 20, but when 8 less than or equal to SNR less than or equal to 16 we see only one line with b less than or equal to 15 km/sec, and two others which we believe have b less than or equal to 20, with values of 20 and 16 km/sec. Traditional Ly alpha line samples which include all lines which have W/sigma(W) greater than or equal to 4 are not adequate to explore the distribution of the properties of individual clouds, because we need much higher (W/sigma(W)) and SNR to avoid the strong biases.

Loglines. May-June 2013

DTIC Science & Technology

2013-06-01

Design: Paul Henry Crank Writers: Beth Reece Sara Moore Amanda Neumann Lally Laksbergs Loglines is prepared electronically, using desktop publishing...just what we used to call ‘part chasers,’” said Andrew Drake, DLA Pacific Logistics Operations Center deputy chief. WSRs and LNOs have to know the...sometimes the services don’t know what details they need to share with us in order for us to better meet their requirements,” he added. Exercise support

Electronic Data Interchange in U.S. Navy Contracting Activities

DTIC Science & Technology

1992-12-01

the basic research question, the following subsidiary questions were asked: 1. How is EDI being used in the private sector and within the Department of...eliminated by using EDI transactions. According to a DoD small business EDI Guide , (DLA Partnership, 1991, p.15) in financial management applications, a...and to place orders against basic ordering agreements (BOA). The ASO is currently transmitting the ASC X12 850 [Purchase Order] to approximately 25

Loglines. January-February 2013

DTIC Science & Technology

2013-02-01

PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Defense Logistics Agency,8725 John J... building on the director’s concept of bring- ing in our industry partners – key DLA suppliers and vendors – to help us meet our goals. During these...Kingman Road Suite 2545,Fort Belvoir,VA,22060-6221 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10

Coal/Biomass-to-Liquids Demonstration Testing for DLA Energy: Report on Project Tests, Evaluations, and Recommendations

DTIC Science & Technology

2015-08-20

elevated temperatures with sub- stoichiometric oxygen to produce primarily hydrogen and carbon monoxide (called syngas). Syngas can be used for the...of the gasifier and flows downward concurrently with nitrogen, pure oxygen , and steam. The EFG operates at very high temperatures (nominal 2,700... temperature slagging gasifiers), these components are cracked and thermally converted to product gas, especially in the presence of steam and oxygen . For

Loglines. January - February 2010

DTIC Science & Technology

2010-02-01

wait around for customers to come to them,” — Army Col. Derek Smith 6 www.dla.mil Logisticians in Europe are working with cus- tomers and suppliers... Derek Smith Warfighter Support Representatives Value-Added Logistics Integrated Support 29Loglines January - February 2010...and d eploy a longsid e them in su pport of con tingen cy operat ions. How l ong h ave y ou wo rked for DL A? I have worked for DL A for a

DLA (Defense Logistics Agency) Quality Circles Workshop Held at Alexandria, Virginia on 7-9 August 1985.

DTIC Science & Technology

1985-08-09

personality conflicts but avoiding group therapy . He discussed the barriers in communicating, such as selective hearing and believing, and stereotyping...Center (DISC) gave a presentation on a sucessful QC project they participated in on a training manual for incoming procurement agents within the DISC...Directorate of Contracting and Production. DI.A Centralized Intern Development Office (DCIDO) is also using the manual to train procurement interns

The Silent Revolution within NATO Logistics: A Study in Afghanistan Fuel and Future Applications

DTIC Science & Technology

2012-12-01

Davis Highway, Suite 1204, Arlington, VA 22202-4302, and to the Office of Management and Budget, Paperwork Reduction Project (0704-0188) Washington, DC...officer technical representatives DCAA Defense Contracting Audit Agency DCMA Defense Contract Management Agency DLA Defense Logistics Agency DoD U.S...thesis will describe what led NATO decision makers to implement such an innovative model as the BOA, and how these individuals managed NATO fuel

Badania Ekologiczne Ryzyka Zachorowań Na Kleszczowe Zapalenie Mózgu W Polsce-Omówienie Metody

PubMed Central

Stefanoff, Paweł; Staszewska, Ewa; Ustrnul, Zbigniew; Rogalska, Justyna; Łankiewicz, Aleksandra; Rosińska, Magdalena

2009-01-01

W pracy omówiono metodologię aktualnie prowadzonych badań ekologicznych kleszczowego zapalenia mózgu (kzm) na terenie Polski. W celu oceny wpływu zróżnicowanych czynników środowiskowych, klimatycznych oraz społecznych na występowanie kzm w różnych regionach Polski zostanie przeprowadzona wieloczynnikoica analiza statystyczna na poziomie gmin dla lat 1999-2006. PMID:22320045

TRANSCOM-DLA: Roles and Responsibilities

DTIC Science & Technology

2017-11-01

Aviation Industrial Hardware Construction &  Equipment   36 Note: For the plot on the right, the underlying number of orders is likewise based on a...services to be provided by the fund, its management structure and how it will meet the following five criteria: 1. Defined organizational “outputs that... structure is working. o There would not be any efficiencies gained from reorganizing or consolidating the two organizations. o There are no functions

A Cost Estimation of Biofuels for Naval Aviation: Budgeting for the Great Green Fleet

DTIC Science & Technology

2011-12-01

from DLA-E, 2011).....10 Figure 8. Pathways for Biomass to Liquid Fuels Production (From Gorin, 2010) ........23 Figure 9. Simplified Process...edible biomass grown on marginal lands and coastal waters. Some are produced using coal to liquid technology. These may be the fuels of the future...liquefaction process  Renewable oils from biomass , and  Alcohols from fermentation of biomass (Hileman et al., 2009, p. 11) The report

Simulations of reactive transport and precipitation with smoothed particle hydrodynamics

NASA Astrophysics Data System (ADS)

Tartakovsky, Alexandre M.; Meakin, Paul; Scheibe, Timothy D.; Eichler West, Rogene M.

2007-03-01

A numerical model based on smoothed particle hydrodynamics (SPH) was developed for reactive transport and mineral precipitation in fractured and porous materials. Because of its Lagrangian particle nature, SPH has several advantages for modeling Navier-Stokes flow and reactive transport including: (1) in a Lagrangian framework there is no non-linear term in the momentum conservation equation, so that accurate solutions can be obtained for momentum dominated flows and; (2) complicated physical and chemical processes such as surface growth due to precipitation/dissolution and chemical reactions are easy to implement. In addition, SPH simulations explicitly conserve mass and linear momentum. The SPH solution of the diffusion equation with fixed and moving reactive solid-fluid boundaries was compared with analytical solutions, Lattice Boltzmann [Q. Kang, D. Zhang, P. Lichtner, I. Tsimpanogiannis, Lattice Boltzmann model for crystal growth from supersaturated solution, Geophysical Research Letters, 31 (2004) L21604] simulations and diffusion limited aggregation (DLA) [P. Meakin, Fractals, scaling and far from equilibrium. Cambridge University Press, Cambridge, UK, 1998] model simulations. To illustrate the capabilities of the model, coupled three-dimensional flow, reactive transport and precipitation in a fracture aperture with a complex geometry were simulated.

Permeability Changes of Coal Cores and Briquettes under Tri-Axial Stress Conditions

NASA Astrophysics Data System (ADS)

Wierzbicki, Mirosław; Konečný, Pavel; Kožušníková, Alena

2014-12-01

The paper is dealing with the permeability of coal in triaxial state of stress. The permeability of coal, besides coal's methane capacity, is the main parameter determining the quantity of methane inflow into underground excavations. The stress in a coal seam is one of the most important factors influencing coal permeability therefore the permeability measurements were performed in tri-axial state of stress. The hydrostatic three-axial state of stress was gradually increased from 5 MPa with steps of 5 MPa up to a maximum of 30 MPa. Nitrogen was applied as a gas medium in all experiments. The results of the permeability measurements of coal cores from the "Zofiówka" mine, Poland, and three mines from the Czech Republic are presented in this paper. As a "reference", permeability measurements were also taken for coal briquettes prepared from coal dust with defined porosity. It was confirmed that the decreasing porosity of coal briquettes affects the decreasing permeability. The advantage of experimentation on coal briquettes is its good repeatability. From the experimental results, an empirical relation between gas permeability and confining pressure has also been identified. The empirical relation for coal briquettes is in good correspondence with published results. However, for coal cores, the character of change differs. The influence of confining pressure has a different character and the decrease in permeability is stronger due to the increasing confining pressure Przepuszczalność węgla, oprócz pojemności sorpcyjnej względem metanu jest głównym parametrem określającym dopływ metanu do podziemnych wyrobiskach górniczych. W warunkach naturalnych wartość przepuszczalności jest ściśle związana ze stanem naprężenia w pokładzie węgla. W pracy przedstawiono wyniki pomiarów przepuszczalności wykonanych w trójosiowym stanie naprężenia. Hydrostatyczny trójosiowy stan naprężenia stopniowo zwiększano od 5 MPa do maksymalnie 30 MPa z krokiem wynoszącym 5 MPa. Maksymalne ciśnienie hydrostatyczne odpowiada ciśnieniu hydrostatycznemu jakie występuje w górotworze nienaruszonym na głębokości około 1200 m. Pomiary przeprowadzono z zastosowaniem azotu na czterech rodzajach rdzeni węglowych. Trzy z nich pochodziły z kopalń czeskich (ČSM, Paskov, František) a czwarty z polskiej kopalni "Zofiówka". Własności węgli i miejsca ich pobrania zestawiono w tablicy 1. Dodatkowo, dla celów porównawczych wykonano pomiary przepuszczalności na materiale "wzorcowym" jakim są brykiety węglowe. Brykiety te wykonano metodą prasowania w urządzeniu pokazanym schematycznie na rys. 2. Własności brykietów zestawiono w tablicy 2, gdzie podano ich gęstości helowe, objętościowe oraz porowatości. Zmienność przepuszczalności wywołana zmianą naprężenia hydrostatycznego może być opisana równaniem empirycznym (3). Wartości przepuszczalności początkowej (dla σ = 0) oraz współczynników B z równania 3, dla różnych porowatości brykietów zestawiono w tablicy 3. Zaletą eksperymentów na brykietach węglowych jest ich powtarzalność. Zmienności przepuszczalności wywołane obciążeniem hydrostatycznym próbek, dla brykietów węglowych oraz rdzeni pokazano na wykresach z rysunku 4. W przypadku rdzeni węglowych zmienność przepuszczalności jest znacznie większa, co wynika prawdopodobnie z występowania szczelin i spękań widocznych na rys 1. Szczeliny te, jako główne drogi transportowe dla gazu przy niskich obciążeniach ulegają zaciśnięciu i część transportu gazu przenosi się do przestrzeni porowej.

Plant Type Selection for Reclamation of Sarcheshmeh Copper Mine Using Fuzzy-Topsis Approach / Wybór Gatunków Roślin Do Wykorzystania W Projekcie Rekultywacji Terenów Kopalni Miedzi Sarcheshmeh Z Wykorzystaniem Metod Logiki Rozmytej Topsis

NASA Astrophysics Data System (ADS)

Ebrahimabadi, Arash; Alavi, Iraj

2013-09-01

Plant species selection is a multi-criteria evaluation decision and has a strategic importance for many companies. The conventional methods for plant species selection are inadequate for dealing with the imprecise or vague nature of linguistic assessment. To overcome this difficulty, fuzzy multi-criteria decision-making methods are proposed. The aim of this study is to use the fuzzy technique for order preference by similarity to ideal solution (F.TOPSIS) methods for the selection of plant species in mine reclamation plan. Plant type selection and planting to protect the environment and the reclamation of the mine are some of the most important solutions. Therefore, the objective of the current research study is to choose the proper plant types for reclamation of Sarcheshmeh Copper Mine using Fuzzy-topsis method. In this regard, primarily, surrounding area of Sarcheshmeh copper mine, one of the world's 10 biggest copper mine which is located near Kerman city of Iran, are surveyed, to choose the best plant type for reclamation of disturbance area. With this respect, based on reclamation plan, primary criteria were consisted of kinds of post mining land use, climate, and nature of soil. Comparison matrixes were then obtained based on experts' opinion and plant types were subsequently prioritized using the Fuzzy Topsis method. Secondary factors considered through the analysis were as follows: perspective of the region, resistance against disease and insects, strength and method of growth, availability to plant type, economic efficiency, protection of soil, storing water, and prevention of pollution. Finally, suitable plant types in the mining perimeter were prioritized as: Amygdalus scoparia, Tamarix, Pistachio Wild, Ephedra, Astragalus, Salsola, respectively. Wybór gatunków roślin jest decyzją podejmowaną w oparciu o wiele kryteriów i stanowi poważne wyzwanie strategiczne dla wielu firm. Konwencjonalne metody wyboru gatunków roślin okazują się niewystarczające w przypadku nieprecyzyjnej oceny i nie w pełni zdefiniowanych określeń językowych. W celu przezwyciężenia tych trudności, zaproponowano wielo-kryterialną metodę decyzyjną wykorzystującą logikę rozmytą. Celem tego opracowania jest ukazanie zastosowania podejścia rozmytego do uzyskania kolejnych przybliżeń do rozwiązania idealnego (F.TOPSIS) przy wyborze odpowiednich gatunków roślin do użycia w projekcie rekultywacji terenów kopalni. Wybór gatunków roślin i ich kultywacja dla zapewnienia ochrony środowiska i projektu rekultywacji terenu pogórniczego to bardzo ważne zagadnienia. Głównym celem obecnego studium jest wybór odpowiednich gatunków roślin do wykorzystania projekcie rekultywacji terenów kopalni miedzi Sarcheshmeh z wykorzystaniem metod logiki rozmytej TOPSIS. W pierwszym rzędzie przeprowadzono badania gruntów wokół kopalni miedzi Sarchesmeh, w pobliżu miejscowości Kerman w Iranie (jednej z dziesięciu największych na świecie kopalni miedzi) w celu wyboru najlepszych typów roślin do wykorzystania do rekultywacji naruszonych działalnością górniczą terenów. Określono podstawowe kryteria wyboru, biorąc pod uwagę plan rekultywacji: sposoby wykorzystania terenu, klimat oraz rodzaje gleb. Otrzymano macierze porównawcze uzyskane na podstawie opinii ekspertów, następnie dokonano określenia priorytetów dla poszczególnych roślin przy pomocy metody TOPSIS, wykorzystującej logikę rozmytą. W analizie uwzględniono następujące czynniki drugorzędne: perspektywy dla regionu, odporność na choroby i owady szkodniki, wytrzymałość i sposób uprawy, dostępność danego gatunku roślin, wydajność ekonomiczna, ochrona gleb, zdolność zatrzymywania wody, zapobieganie zanieczyszczeniom. W końcowym etapie dokonano wyboru najkorzystniejszych dla danego terenu górniczego gatunków roślin, podając kolejno: Amygdalus scoparia, Tamarix, Pistachio Wild, Ephedra, Astragalus, Salsola.

Modeling Water Balance of Dammed Lakes Using Computer Code Matlab-Simulink/ Modelowanie Bilansu Wodnego Piętrzonych Jezior Za Pomocą Programu Komputerowego Matlab-Simulink

NASA Astrophysics Data System (ADS)

Błażejewski, Ryszard; Murat-Błażejewska, Sadżide; Jędrkowiak, Martyna

2014-09-01

The paper presents a water balance of a flow-through, dammed lake, consisted of the following terms: surface inflow, underground inflow/outflow based on the Dupuit's equation, precipitation on the lake surface, evaporation from water surface and outflow from the lake at which a damming weir is located. The balance equation was implemented Matlab-Simulink®. Applicability of the model was assessed on the example of the Sławianowskie Lake of surface area 276 ha and mean depth - 6.6 m, Water balances, performed for month time intervals in the hydrological year 2009, showed good agreement for the first three months only. It is concluded that the balancing time interval should be shorter (1 day) to minimize the errors. For calibration purposes, measurements of ground water levels in the vicinity of the lake are also recommended. Praca przedstawia bilans wodny przepływowego piętrzonego jeziora, uwzględniający dopływ powierzchniowy, dopływ i odpływ podziemny opisany równaniem Dupuita, opad na powierzchnię jeziora, parowanie z powierzchni wody oraz odpływ w przekroju zamkniętym jazem piętrzącym. Z uwagi na nieliniowe związki wymienionych składników bilansu z poziomem wody w jeziorze, do obliczeń wykorzystano program komuterowy Matlab-Simulink®. Przydatność modelu sprawdzono na przykładzie Jeziora Sławianowskiego o powierzchni 276 ha i średniej głębokości - 6,6 m. Jezioro to zostało podzielone na dwa akweny o zróżnicowanej głębokości. Wyniki obliczeń miesięcznych bilansów wodnych dla roku hydrologicznego 2009, wykazały dobrą zgodność z pomiarami jedynie dla trzech pierwszych miesięcy. Stwierdzono, że dla zmniejszenia błędów obliczeniowych należałoby skrócić interwał bilansowania do jednej doby. Kalibracja modelu byłaby łatwiejsza i bardziej adekwatna, gdyby do oszacowania przewodności hydraulicznej przyległych do jeziora gruntów i osadów dennych wykorzystać badania poziomów wody w piezometrach, zlokalizowanych w kilku transektach, prostopadłych do linii brzegowej jeziora.

Compendium of Operations Research and Economic Analysis Studies

DTIC Science & Technology

1992-10-01

were to: (1) review and document current po~icios and procedures, k2) identity relevant economic and non -economic decision vAriibles, (3) design a...minimize the total sample size while ensuring that the proportion of samples closely resembled the actual population proportions. Both linear and non ...would cost about $290.00. DLA-92-PlO10. Impact of Increasing the Non -Competitive Threshold from Index No. 92-26 $2,500 to $5,000 (October 1991) In

Dollar Summary of Federal Supply Classification and Service Category by Company, FY84, Part 3 (4610-5925).

DTIC Science & Technology

1984-01-01

TECHNOLOGY INC TEXAS USAF AIRCRAFT MAINTENANCE & REPAIR SHOP EQUIP 454 MENSOR CORPORATION TEXAS NAVY AIRCRAFT MAINTENANCE & REPAIR SHOP EQUIP 37 MICRO DYNAMICS...VAULT COMPANY INC CALIFORNIA DLA BUILDING GLASS TILE BRICK AND BLOCK 8 FSC TOTAL 1C.776 3530 OFFICINA DE SERVICIOS MULTIPLE HONDURAS ARMY PIPE AND...EXCEPT AIRBORNE 731 CONTRACTOR TOTAL 115 MICPO CONSULTANTS INC CALIFORNIA ARMY RADIO TV EQUIPMENT EXCEPT AIRBORNE 193 MICRO -TEL CORPORATION MARYLAND NAVY

Total Quality Management Office for Contracting Integrity Implementation Plan

DTIC Science & Technology

1989-07-01

REPORT______ANDDATESCOVERED 4. TITLE AND SUBTITLE S. FUNDING NUMBERS Total Quality Management Office for Contracting Integrity Implementatiun Plan 6. AUTHOR(S) 7...01-280-5500 Standard Form 298 (Rev. 2-89) P’,croed 1:, ANSI Std 3J9-16 29d. 102 4 TOTAL QUALITY MANAGEMENT OFFICE FOR CONTRACTING INTEGRITY...IMPLEMENTATION PLAN According to the Total Quality Management (TQM) Master Plan, each PSE head, supported by Working Groups, will implement the HQ DLA Master

Summary Report on the Audit of Defense Logistics Agency 1995 Defense Base Realignment and Closure Data Collection Process.

DTIC Science & Technology

1995-06-19

VXW-ÄVAVKVX’AWXW/XVXV:*: OFFICE OF THE INSPECTOR GENERAL SUMMARY REPORT ON THE AUDIT OF DEFENSE LOGISTICS AGENCY 1995 DEFENSE BASE REALIGNMENT...FOR DIRECTOR, DEFENSE LOGISTICS AGENCY SUBJECT: Summary Report on the Audit of Defense Logistics Agency 1995 Defense Base Realignment and Closure...the data that DLA provides to support recommendations for the 1995 Commission. The specific objective for the audits was to determine whether the

Metals Additive Manufacturing. Great Promise in Mitigating Shortages but Some Risks Remain

DTIC Science & Technology

2016-11-01

manufac- tured, shrinking development and delivery cycle times, and yielding improved performance at a lower cost per part. Shapes previously not...make a part. As illustrated in Figure 1, after each pass, a new layer of powder is laid down using a recoater blade and the process continues until...suggested deliberately abandon- ing large production runs and stockpiled inventories. The Defense Logistics Agency (DLA) lists AM as a priority in its R

Improving DLA Supply Chain Agility: Lead Times, Order Quantities, and Information Flow

DTIC Science & Technology

2015-01-01

effective inventory management. The dynamism of supply appears to be less than demand, with major problems from supply-side vola- tility not apparent...presents a challenge for efficient and effective inventory management. The dynamism of supply appears to be much less, with major problems from...a vehicle safety problem that newly appears. Or the lead time for the customer change of plan may be less than the lead time to procure the item. So

Improvements Needed in the Defense Logistics Agencys Evaluation of Fair and Reasonable Prices for C130 Aircraft Spare Parts (Redacted)

DTIC Science & Technology

2015-11-16

mandatory disclosure under the Freedom of Information Act. Mission Our mission is to provide independent, relevant, and timely oversight of the Department...of Defense that supports the warfighter; promotes accountability , integrity, and efficiency; advises the Secretary of Defense and Congress; and...for the 10 parts, as illustrated in Table 1, UTAS’s propeller aftermarket sales of to DLA Aviation accounted for of UTAS’s total sales. However

DLA TEST Defense Infrastructure: Improvement Needed in Energy Reporting and Security Funding at Installations with Limited Connectivity

DTIC Science & Technology

2016-01-01

2013 Annual Energy Management Report 20 Figure 7: 1.4 Megawatt Generators at Landfill Gas Plant at Joint Base Elmendorf-Richardson, Alaska 24...has significant redundancy through its onsite landfill gas electrical generation plant which, in combination with back-up generators, can provide...DOD Energy Management Figure 7: 1.4 Megawatt Generators at Landfill Gas Plant at Joint Base Elmendorf- Richardson, Alaska We also found that the

Installation Restoration Program. Preliminary Assessment: 183rd Tactical Fighter Group, Illinois Air National Guard, Capital Airport, Springfield, Illinois

DTIC Science & Technology

1990-05-01

11140 Rockville Pike Rockville, Maryland 20852 Contract No. DLA 900-82-C-4426 Completed by Science & Technology, Inc. 704 South Illinois Avenue Suite C... Environments . .......... 111-19 IV. SITE EVALUATION...................v-i *A. Activity Review ................. v-i B. Disposal/Spill Site Identification...approximately 120 feet north of a small pond and creek located on the south side of the airport on airport property. The Base conducted operations at

Feasibility and patient acceptability of a novel artificial intelligence-based screening model for diabetic retinopathy at endocrinology outpatient services: a pilot study.

PubMed

Keel, Stuart; Lee, Pei Ying; Scheetz, Jane; Li, Zhixi; Kotowicz, Mark A; MacIsaac, Richard J; He, Mingguang

2018-03-12

The purpose of this study is to evaluate the feasibility and patient acceptability of a novel artificial intelligence (AI)-based diabetic retinopathy (DR) screening model within endocrinology outpatient settings. Adults with diabetes were recruited from two urban endocrinology outpatient clinics and single-field, non-mydriatic fundus photographs were taken and graded for referable DR ( ≥ pre-proliferative DR). Each participant underwent; (1) automated screening model; where a deep learning algorithm (DLA) provided real-time reporting of results; and (2) manual model where retinal images were transferred to a retinal grading centre and manual grading outcomes were distributed to the patient within 2 weeks of assessment. Participants completed a questionnaire on the day of examination and 1-month following assessment to determine overall satisfaction and the preferred model of care. In total, 96 participants were screened for DR and the mean assessment time for automated screening was 6.9 minutes. Ninety-six percent of participants reported that they were either satisfied or very satisfied with the automated screening model and 78% reported that they preferred the automated model over manual. The sensitivity and specificity of the DLA for correct referral was 92.3% and 93.7%, respectively. AI-based DR screening in endocrinology outpatient settings appears to be feasible and well accepted by patients.

Microbial production of lactic acid: the latest development.

PubMed

Juturu, Veeresh; Wu, Jin Chuan

2016-12-01

Lactic acid is an important platform chemical for producing polylactic acid (PLA) and other value-added products. It is naturally produced by a wide spectrum of microbes including bacteria, yeast and filamentous fungi. In general, bacteria ferment C5 and C6 sugars to lactic acid by either homo- or hetero-fermentative mode. Xylose isomerase, phosphoketolase, transaldolase, l- and d-lactate dehydrogenases are the key enzymes that affect the ways of lactic acid production. Metabolic engineering of microbial strains are usually needed to produce lactic acid from unconventional carbon sources. Production of d-LA has attracted much attention due to the demand for producing thermostable PLA, but large scale production of d-LA has not yet been commercialized. Thermophilic Bacillus coagulans strains are able to produce l-lactic acid from lignocellulose sugars homo-fermentatively under non-sterilized conditions, but the lack of genetic tools for metabolically engineering them severely affects their development for industrial applications. Pre-treatment of agriculture biomass to obtain fermentable sugars is a pre-requisite for utilization of the huge amounts of agricultural biomass to produce lactic acid. The major challenge is to obtain quality sugars of high concentrations in a cost effective-way. To avoid or minimize the use of neutralizing agents during fermentation, genetically engineering the strains to make them resist acidic environment and produce lactic acid at low pH would be very helpful for reducing the production cost of lactic acid.

Numerical Simulations of Single and Multiple Scattering by Fractal Ice Clusters

NASA Technical Reports Server (NTRS)

Dlugach, Janna M.; Mishchenko, Michael I.; Mackowski, Daniel W.

2011-01-01

We consider the scattering model in the form of a vertically and horizontally homogeneous particulate slab of an arbitrary optical thickness composed of widely separated fractal aggregates built of small spherical ice monomers. The aggregates are generated by applying three different approaches, including simulated cluster-cluster aggregation (CCA) and diffusion-limited aggregation (DLA) procedures. Having in mind radar remote-sensing applications, we report and analyze the results of computations of the backscattering circular polarization ratio obtained using efficient superposition T-matrix and vector radiative-transfer codes. The computations have been performed at a wavelength of 12.6 cm for fractal aggregates with the following characteristics: monomer refractive index m=1.78+i0.003, monomer radius r=1 cm, monomer packing density p=0.2, overall aggregate radii R in the range 4<=R<=10 cm and fractal dimensions D(sub f) 2.5 and 3. We show that for aggregates generated with simulated CCA and DLA procedures, the respective values of the backscattering circular polarization ratio differ weakly for D(sub f) 2.5, but the differences can increase somewhat for D(sub f)3, especially in case of an optically semi-infinite medium. For aggregates with a spheroidal overall shape, the dependence of the circular polarization ratio on the cluster morphology can be quite significant and increases with increasing the aspect ratio of the circumscribing spheroid.

Organic Hydroperoxide Resistance Protein and Ergothioneine Compensate for Loss of Mycothiol in Mycobacterium smegmatis Mutants▿†

PubMed Central

Ta, Philong; Buchmeier, Nancy; Newton, Gerald L.; Rawat, Mamta; Fahey, Robert C.

2011-01-01

The mshA::Tn5 mutant of Mycobacterium smegmatis does not produce mycothiol (MSH) and was found to markedly overproduce both ergothioneine and an ∼15-kDa protein determined to be organic hydroperoxide resistance protein (Ohr). An mshA(G32D) mutant lacking MSH overproduced ergothioneine but not Ohr. Comparison of the mutant phenotypes with those of the wild-type strain indicated the following: Ohr protects against organic hydroperoxide toxicity, whereas ergothioneine does not; an additional MSH-dependent organic hydroperoxide peroxidase exists; and elevated isoniazid resistance in the mutant is associated with both Ohr and the absence of MSH. Purified Ohr showed high activity with linoleic acid hydroperoxide, indicating lipid hydroperoxides as the likely physiologic targets. The reduction of oxidized Ohr by NADH was shown to be catalyzed by lipoamide dehydrogenase and either lipoamide or DlaT (SucB). Since free lipoamide and lipoic acid levels were shown to be undetectable in M. smegmatis, the bound lipoyl residues of DlaT are the likely source of the physiological dithiol reductant for Ohr. The pattern of occurrence of homologs of Ohr among bacteria suggests that the ohr gene has been distributed by lateral transfer. The finding of multiple Ohr homologs with various sequence identities in some bacterial genomes indicates that there may be multiple physiologic targets for Ohr proteins. PMID:21335456

Self-organization of developing embryo using scale-invariant approach

PubMed Central

2011-01-01

Background Self-organization is a fundamental feature of living organisms at all hierarchical levels from molecule to organ. It has also been documented in developing embryos. Methods In this study, a scale-invariant power law (SIPL) method has been used to study self-organization in developing embryos. The SIPL coefficient was calculated using a centro-axial skew symmetrical matrix (CSSM) generated by entering the components of the Cartesian coordinates; for each component, one CSSM was generated. A basic square matrix (BSM) was constructed and the determinant was calculated in order to estimate the SIPL coefficient. This was applied to developing C. elegans during early stages of embryogenesis. The power law property of the method was evaluated using the straight line and Koch curve and the results were consistent with fractal dimensions (fd). Diffusion-limited aggregation (DLA) was used to validate the SIPL method. Results and conclusion The fractal dimensions of both the straight line and Koch curve showed consistency with the SIPL coefficients, which indicated the power law behavior of the SIPL method. The results showed that the ABp sublineage had a higher SIPL coefficient than EMS, indicating that ABp is more organized than EMS. The fd determined using DLA was higher in ABp than in EMS and its value was consistent with type 1 cluster formation, while that in EMS was consistent with type 2. PMID:21635789

Self-organization of developing embryo using scale-invariant approach.

PubMed

Tiraihi, Ali; Tiraihi, Mujtaba; Tiraihi, Taki

2011-06-03

Self-organization is a fundamental feature of living organisms at all hierarchical levels from molecule to organ. It has also been documented in developing embryos. In this study, a scale-invariant power law (SIPL) method has been used to study self-organization in developing embryos. The SIPL coefficient was calculated using a centro-axial skew symmetrical matrix (CSSM) generated by entering the components of the Cartesian coordinates; for each component, one CSSM was generated. A basic square matrix (BSM) was constructed and the determinant was calculated in order to estimate the SIPL coefficient. This was applied to developing C. elegans during early stages of embryogenesis. The power law property of the method was evaluated using the straight line and Koch curve and the results were consistent with fractal dimensions (fd). Diffusion-limited aggregation (DLA) was used to validate the SIPL method. The fractal dimensions of both the straight line and Koch curve showed consistency with the SIPL coefficients, which indicated the power law behavior of the SIPL method. The results showed that the ABp sublineage had a higher SIPL coefficient than EMS, indicating that ABp is more organized than EMS. The fd determined using DLA was higher in ABp than in EMS and its value was consistent with type 1 cluster formation, while that in EMS was consistent with type 2. © 2011 Tiraihi et al; licensee BioMed Central Ltd.

A cell-based MHC stabilization assay for the detection of peptide binding to the canine classical class I molecule, DLA-88.

PubMed

Ross, Peter; Holmes, Jennifer C; Gojanovich, Gregory S; Hess, Paul R

2012-12-15

Identifying immunodominant CTL epitopes is essential for studying CD8+ T-cell responses in populations, but remains difficult, as peptides within antigens typically are too numerous for all to be synthesized and screened. Instead, to facilitate discovery, in silico scanning of proteins for sequences that match the motif, or binding preferences, of the restricting MHC class I allele - the largest determinant of immunodominance - can be used to predict likely candidates. The high false positive rate with this analysis ideally requires binding confirmation, which is obtained routinely by an assay using cell lines such as RMA-S that have defective transporter associated with antigen processing (TAP) machinery, and consequently, few surface class I molecules. The stabilization and resultant increased life-span of peptide-MHC complexes on the cell surface by the addition of true binders validates their identity. To determine whether a similar assay could be developed for dogs, we transfected a prevalent class I allele, DLA-88*50801, into RMA-S. In the BARC3 clone, the recombinant heavy chain was associated with murine β2-microglobulin, and importantly, could differentiate motif-matched and -mismatched peptides by surface MHC stabilization. This work demonstrates the potential to use RMA-S cells transfected with canine alleles as a tool for CTL epitope discovery in this species. Copyright © 2012 Elsevier B.V. All rights reserved.

ADDRESSING THE DEFICIT: Updating the Budgetary Implications of Selected GAO Work

DTIC Science & Technology

1996-06-01

DGPS DI DLA DOD DOE DOT DUR EDWAA EM EPA FAIR FAA FAS FDIC FHWA FY GAO GSA HACCP HCFA HHS HMO HUD IDB IFAD INS IRS JCT...Marti, the broadcasts are constantly and effectively jammed , USIA’S research data shows that, mainly as a result of the jamming , the number of Cubans...hours (from 3:30 am to 8:00 am), but Cuban jamming also expanded. In an attempt to overcome jamming , TV Marti has plans to convert from VHF to UHF