Computer vision-based diameter maps to study fluoroscopic recordings of small intestinal motility from conscious experimental animals.

PubMed

Ramírez, I; Pantrigo, J J; Montemayor, A S; López-Pérez, A E; Martín-Fontelles, M I; Brookes, S J H; Abalo, R

2017-08-01

When available, fluoroscopic recordings are a relatively cheap, non-invasive and technically straightforward way to study gastrointestinal motility. Spatiotemporal maps have been used to characterize motility of intestinal preparations in vitro, or in anesthetized animals in vivo. Here, a new automated computer-based method was used to construct spatiotemporal motility maps from fluoroscopic recordings obtained in conscious rats. Conscious, non-fasted, adult, male Wistar rats (n=8) received intragastric administration of barium contrast, and 1-2 hours later, when several loops of the small intestine were well-defined, a 2 minutes-fluoroscopic recording was obtained. Spatiotemporal diameter maps (Dmaps) were automatically calculated from the recordings. Three recordings were also manually analyzed for comparison. Frequency analysis was performed in order to calculate relevant motility parameters. In each conscious rat, a stable recording (17-20 seconds) was analyzed. The Dmaps manually and automatically obtained from the same recording were comparable, but the automated process was faster and provided higher resolution. Two frequencies of motor activity dominated; lower frequency contractions (15.2±0.9 cpm) had an amplitude approximately five times greater than higher frequency events (32.8±0.7 cpm). The automated method developed here needed little investigator input, provided high-resolution results with short computing times, and automatically compensated for breathing and other small movements, allowing recordings to be made without anesthesia. Although slow and/or infrequent events could not be detected in the short recording periods analyzed to date (17-20 seconds), this novel system enhances the analysis of in vivo motility in conscious animals. © 2017 John Wiley & Sons Ltd.

catena-Poly[[bis­[4-(dimethyl­amino)­pyridine-κN 1]cobalt(II)]-di-μ-azido-κ4 N 1:N 3

PubMed Central

Guenifa, Fatiha; Zeghouan, Ouahida; Hadjadj, Nasreddine; Bendjeddou, Lamia; Merazig, Hocine

2013-01-01

The title layered polymer, [Co(N3)2(C7H10N2)2]n, contains CoII, azide and 4-(dimethyl­amino)­pyridine (4-DMAP) species with site symmetries m2m, 2 and m, respectively. The Co2+ ion adopts an octa­hedral coordination geometry in which four N atoms from azide ligands lie in the equatorial plane and two 4-DMAP N atoms occupy the axial positions. The CoII atoms are connected by two bridging azide ligands, resulting in a chain parallel to the c axis. PMID:23476514

Structural and physicochemical characterization of pyridine derivative salts of anti-inflammatory drugs

NASA Astrophysics Data System (ADS)

Nechipadappu, Sunil Kumar; Trivedi, Darshak R.

2017-08-01

Salts of common anti-inflammatory drugs mefenamic acid (MFA), tolfenamic acid (TFA) and naproxen (NPX) with various pyridine derivatives (4-amino pyridine (4AP), 4-dimethylaminopyridine (DMAP) and 2-amino pyridine (2AP)) were synthesized by crystal engineering approach based on the pKa values of API's and the salt former. All the salts were characterized systematically by various spectroscopic methods including FT-IR and 1H NMR and the crystal structure was determined by single-crystal X-ray diffraction techniques (SCXRD). DMAP salt of NPX and 2AP salts of MFA and TFA were not obtained in the salt screening experiments. All the molecular salts exhibited 1:1 molecular stoichiometry in the asymmetric unit and except NPX-2AP salt, all the molecular salts included a water molecule in the crystal lattice. Physicochemical and structural properties between drug-drug molecular salts of MFA-4AP, TFA-4AP and NPX-4AP have been evaluated and it was found that these molecular salts were found to be stable for a time period of six months at ambient condition and further hydration of molecular salts were not observed even at accelerated humid conditions (∼75% RH). It was found that 4AP salts of MFA and TFA and DMAP salts of MFA and TFA are isostructural.

NASTRAN DMAP Fuzzy Structures Analysis: Summary of Research

NASA Technical Reports Server (NTRS)

Sparrow, Victor W.

2001-01-01

The main proposed tasks of Cooperative Agreement NCC1-382 were: (1) developing MSC/NASTRAN DMAP language scripts to implement the Soize fuzzy structures approach for modeling the dynamics of complex structures; (2) benchmarking the results of the new code to those for a cantilevered beam in the literature; and (3) testing and validating the new code by comparing the fuzzy structures results to NASA Langley experimental and conventional finite element results for two model test structures representative of aircraft fuselage sidewall construction: (A) a small aluminum test panel (SLP, single longeron panel) with a single longitudinal stringer attached with bolts; and (B) a 47 by 72 inch flat aluminum fuselage panel (AFP, aluminum fuselage panel) including six longitudinal stringers and four frame stiffeners attached with rivets.

Solving Modal Equations of Motion with Initial Conditions Using MSC/NASTRAN DMAP. Part 2; Coupled Versus Uncoupled Integration

NASA Technical Reports Server (NTRS)

Barnett, Alan R.; Ibrahim, Omar M.; Abdallah, Ayman A.; Sullivan, Timothy L.

1993-01-01

By utilizing MSC/NASTRAN DMAP (Direct Matrix Abstraction Program) in an existing NASA Lewis Research Center coupled loads methodology, solving modal equations of motion with initial conditions is possible using either coupled (Newmark-Beta) or uncoupled (exact mode superposition) integration available within module TRD1. Both the coupled and newly developed exact mode superposition methods have been used to perform transient analyses of various space systems. However, experience has shown that in most cases, significant time savings are realized when the equations of motion are integrated using the uncoupled solver instead of the coupled solver. Through the results of a real-world engineering analysis, advantages of using the exact mode superposition methodology are illustrated.

The influence of steric hindrance on kinetics and isotope effects in the reaction of 2,2-bis(4-dimethylaminophenyl)-1-nitro-1-(4-nitrophenyl)ethane with DBU base in acetonitrile

NASA Astrophysics Data System (ADS)

Nowak, Iwona; Jarczewski, Arnold

2014-11-01

The pKa value for 2,2-bis(4-dimethylaminophenyl)-1-nitro-1-(4-nitrophenyl)ethane, (dmap)2 (pKa = 25.11) has been measured spectrophotometrically using buffer solutions of a few strong amine bases: 1,8-diazabicyclo[5.4.0]undec-7-ene, (DBU); 1,1,3,3-tetramethylguanidine, (TMG); 1,5,7-triazabicyclo[4.4.0]dec-5-ene, (TBD); 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene, (MTBD) and their salts. The low energy conformers of nitrophenyl nitroalkanes have been determined using the semiempirical PM6 methods, (B3-LYP) density functional theory (DFT) together with the 6-31G(d,p) basis set. The participation of the low energy conformer in the proton transfer reaction to DBU base has been discussed. The kinetic data for proton transfer reactions between (dmap)2 and DBU in acetonitrile (MeCN) at pseudo-first order conditions have been presented. The influence of steric hindrance brought by reacting C-acid and organic base on the stability of the transition state has been discussed. The rates of second-order rate constants for series of nitrophenyl nitroalkanes, NO2PhCHRNO2 (R = Me; Et; iPr; dimethylaminophenyl = (dmap)2) are presented and discussed.

HIGH-PRECISION BIOLOGICAL EVENT EXTRACTION: EFFECTS OF SYSTEM AND OF DATA

PubMed Central

Cohen, K. Bretonnel; Verspoor, Karin; Johnson, Helen L.; Roeder, Chris; Ogren, Philip V.; Baumgartner, William A.; White, Elizabeth; Tipney, Hannah; Hunter, Lawrence

2013-01-01

We approached the problems of event detection, argument identification, and negation and speculation detection in the BioNLP’09 information extraction challenge through concept recognition and analysis. Our methodology involved using the OpenDMAP semantic parser with manually written rules. The original OpenDMAP system was updated for this challenge with a broad ontology defined for the events of interest, new linguistic patterns for those events, and specialized coordination handling. We achieved state-of-the-art precision for two of the three tasks, scoring the highest of 24 teams at precision of 71.81 on Task 1 and the highest of 6 teams at precision of 70.97 on Task 2. We provide a detailed analysis of the training data and show that a number of trigger words were ambiguous as to event type, even when their arguments are constrained by semantic class. The data is also shown to have a number of missing annotations. Analysis of a sampling of the comparatively small number of false positives returned by our system shows that major causes of this type of error were failing to recognize second themes in two-theme events, failing to recognize events when they were the arguments to other events, failure to recognize nontheme arguments, and sentence segmentation errors. We show that specifically handling coordination had a small but important impact on the overall performance of the system. The OpenDMAP system and the rule set are available at http://bionlp.sourceforge.net. PMID:25937701

Time-resolved mapping of water diffusion coefficients in a working soft actuator device.

PubMed

Naji, Leila; Chudek, John A; Baker, Richard T

2008-08-14

Diffusion-weighted imaging was employed to spatially map the distribution of the diffusion coefficient of water, D, in bare, water-soaked, Li(+)-exchanged, cast Nafion and in an ionic polymer-metal composite (IPMC) soft actuator element, prepared from this bare Nafion by impregnation with Pt electrodes. D was evaluated in two orthogonal directions: along one of the long dimensions of the sample (Dx) and through its thickness (Dz). D-maps of the IPMC element were obtained both in the absence of an applied potential and in situ during the application of a 3 V dc potential across the thickness of the sample. In the bare Nafion, D-maps showed uniform values of both Dx and Dz of about 6 x 10 (-10) m(2) s(-1). In the IPMC two effects were observed: (i) D at the electroded surfaces of the IPMC was higher than at the center of the sample; (ii) this difference was much greater in Dz than in Dx . Both effects were explained by the influence of the impregnated Pt electrodes on polymer structure. The D-maps in the electrochemical measurements showed high values of D (up to 8 x 10(-10) m(2) s(-1)) at the cathode and low values (from 1 x 10(-10) m(2) s(-1)) at the anode. This was explained in terms of the effect on the Nafion nanostructure of the forced electro-migration of Li(H2O)x(+) species toward the cathode.

Fall Prevention Self-Assessments Via Mobile 3D Visualization Technologies: Community Dwelling Older Adults’ Perceptions of Opportunities and Challenges

PubMed Central

Hamm, Julian; Atwal, Anita

2017-01-01

Background In the field of occupational therapy, the assistive equipment provision process (AEPP) is a prominent preventive strategy used to promote independent living and to identify and alleviate fall risk factors via the provision of assistive equipment within the home environment. Current practice involves the use of paper-based forms that include 2D measurement guidance diagrams that aim to communicate the precise points and dimensions that must be measured in order to make AEPP assessments. There are, however, issues such as “poor fit” of equipment due to inaccurate measurements taken and recorded, resulting in more than 50% of equipment installed within the home being abandoned by patients. This paper presents a novel 3D measurement aid prototype (3D-MAP) that provides enhanced measurement and assessment guidance to patients via the use of 3D visualization technologies. Objective The purpose of this study was to explore the perceptions of older adults with regard to the barriers and opportunities of using the 3D-MAP application as a tool that enables patient self-delivery of the AEPP. Methods Thirty-three community-dwelling older adults participated in interactive sessions with a bespoke 3D-MAP application utilizing the retrospective think-aloud protocol and semistructured focus group discussions. The system usability scale (SUS) questionnaire was used to evaluate the application’s usability. Thematic template analysis was carried out on the SUS item discussions, think-aloud, and semistructured focus group data. Results The quantitative SUS results revealed that the application may be described as having “marginal-high” and “good” levels of usability, along with strong agreement with items relating to the usability (P=.004) and learnability (P<.001) of the application. Four high-level themes emerged from think-aloud and focus groups discussions: (1) perceived usefulness (PU), (2) perceived ease of use (PEOU), (3) application use (AU) and (4) self-assessment (SA). The application was seen as a useful tool to enhance visualization of measurement guidance and also to promote independent living, ownership of care, and potentially reduce waiting times. Several design and functionality recommendations emerged from the study, such as a need to manipulate the view and position of the 3D furniture models, and a need for clearer visual prompts and alternative keyboard interface for measurement entry. Conclusions Participants perceived the 3D-MAP application as a useful tool that has the potential to make significant improvements to the AEPP, not only in terms of accuracy of measurement, but also by potentially enabling older adult patients to carry out the data collection element of the AEPP themselves. Further research is needed to further adapt the 3D-MAP application in line with the study outcomes and to establish its clinical utility with regards to effectiveness, efficiency, accuracy, and reliability of measurements that are recorded using the application and to compare it with 2D measurement guidance leaflets. PMID:28630034

Mesoporous gold sponges: electric charge-assisted seed mediated synthesis and application as surface-enhanced Raman scattering substrates

NASA Astrophysics Data System (ADS)

Yi, Zao; Luo, Jiangshan; Tan, Xiulan; Yi, Yong; Yao, Weitang; Kang, Xiaoli; Ye, Xin; Zhu, Wenkun; Duan, Tao; Yi, Yougen; Tang, Yongjian

2015-11-01

Mesoporous gold sponges were prepared using 4-dimethylaminopyridine (DMAP)-stabilized Au seeds. This is a general process, which involves a simple template-free method, room temperature reduction of HAuCl4·4H2O with hydroxylamine. The formation process of mesoporous gold sponges could be accounted for the electrostatic interaction (the small Au nanoparticles (~3 nm) and the positively charged DMAP-stabilized Au seeds) and Ostwald ripening process. The mesoporous gold sponges had appeared to undergo electrostatic adsorption initially, sequentially linear aggregation, welding and Ostwald ripening, then, they randomly cross link into self-supporting, three-dimensional networks with time. The mesoporous gold sponges exhibit higher surface area than the literature. In addition, application of the spongelike networks as an active material for surface-enhanced Raman scattering has been investigated by employing 4-aminothiophenol (4-ATP) molecules as a probe.

Mesoporous gold sponges: electric charge-assisted seed mediated synthesis and application as surface-enhanced Raman scattering substrates

PubMed Central

Yi, Zao; Luo, Jiangshan; Tan, Xiulan; Yi, Yong; Yao, Weitang; Kang, Xiaoli; Ye, Xin; Zhu, Wenkun; Duan, Tao; Yi, Yougen; Tang, Yongjian

2015-01-01

Mesoporous gold sponges were prepared using 4-dimethylaminopyridine (DMAP)-stabilized Au seeds. This is a general process, which involves a simple template-free method, room temperature reduction of HAuCl4·4H2O with hydroxylamine. The formation process of mesoporous gold sponges could be accounted for the electrostatic interaction (the small Au nanoparticles (~3 nm) and the positively charged DMAP-stabilized Au seeds) and Ostwald ripening process. The mesoporous gold sponges had appeared to undergo electrostatic adsorption initially, sequentially linear aggregation, welding and Ostwald ripening, then, they randomly cross link into self-supporting, three-dimensional networks with time. The mesoporous gold sponges exhibit higher surface area than the literature. In addition, application of the spongelike networks as an active material for surface-enhanced Raman scattering has been investigated by employing 4-aminothiophenol (4-ATP) molecules as a probe. PMID:26538365

Simultaneous removal of ammonia and N-nitrosamine precursors from high ammonia water by zeolite and powdered activated carbon.

PubMed

Xue, Runmiao; Donovan, Ariel; Zhang, Haiting; Ma, Yinfa; Adams, Craig; Yang, John; Hua, Bin; Inniss, Enos; Eichholz, Todd; Shi, Honglan

2018-02-01

When adding sufficient chlorine to achieve breakpoint chlorination to source water containing high concentration of ammonia during drinking water treatment, high concentrations of disinfection by-products (DBPs) may form. If N-nitrosamine precursors are present, highly toxic N-nitrosamines, primarily N-nitrosodimethylamine (NDMA), may also form. Removing their precursors before disinfection should be a more effective way to minimize these DBPs formation. In this study, zeolites and activated carbon were examined for ammonia and N-nitrosamine precursor removal when incorporated into drinking water treatment processes. The test results indicate that Mordenite zeolite can remove ammonia and five of seven N-nitrosamine precursors efficiently by single step adsorption test. The practical applicability was evaluated by simulation of typical drinking water treatment processes using six-gang stirring system. The Mordenite zeolite was applied at the steps of lime softening, alum coagulation, and alum coagulation with powdered activated carbon (PAC) sorption. While the lime softening process resulted in poor zeolite performance, alum coagulation did not impact ammonia and N-nitrosamine precursor removal. During alum coagulation, more than 67% ammonia and 70%-100% N-nitrosamine precursors were removed by Mordenite zeolite (except 3-(dimethylaminomethyl)indole (DMAI) and 4-dimethylaminoantipyrine (DMAP)). PAC effectively removed DMAI and DMAP when added during alum coagulation. A combination of the zeolite and PAC selected efficiently removed ammonia and all tested seven N-nitrosamine precursors (dimethylamine (DMA), ethylmethylamine (EMA), diethylamine (DEA), dipropylamine (DPA), trimethylamine (TMA), DMAP, and DMAI) during the alum coagulation process. Copyright © 2017. Published by Elsevier B.V.

Somatic cell cloning in Buffalo (Bubalus bubalis): effects of interspecies cytoplasmic recipients and activation procedures.

PubMed

Kitiyanant, Y; Saikhun, J; Chaisalee, B; White, K L; Pavasuthipaisit, K

2001-01-01

Successful nuclear transfer (NT) of somatic cell nuclei from various mammalian species to enucleated bovine oocytes provides a universal cytoplast for NT in endangered or extinct species. Buffalo fetal fibroblasts were isolated from a day 40 fetus and were synchronized in presumptive G(0) by serum deprivation. Buffalo and bovine oocytes from abattoir ovaries were matured in vitro and enucleated at 22 h. In the first experiment, we compared the ability of buffalo and bovine oocyte cytoplasm to support in vitro development of NT embryos produced by buffalo fetal fibroblasts as donor nuclei. There were no significant differences (p > 0.05) between the NT embryos derived from buffalo and bovine oocytes, in fusion (74% versus 71%) and cleavage (77% versus 75%) rates, respectively. No significant differences were also observed in blastocyst development (39% versus 33%) and the mean cell numbers of day 7 cloned blastocysts (88.5 +/- 25.7 versus 51.7 +/- 5.4). In the second experiment, we evaluated the effects of activation with calcium ionophore A23187 on development of NT embryos after electrical fusion. A significantly higher (p < 0.05) percentage of blastocyst development was observed in the NT embryos activated by calcium ionophore and 6-DMAP when compared with 6-DMAP alone (33% versus 17%). The results indicate that the somatic nuclei from buffalo can be reprogrammed after transfer to enucleated bovine oocytes, resulting in the production of cloned buffalo blastocysts similar to those transferred into buffalo oocytes. Calcium ionophore used in conjunction with 6-DMAP effectively induces NT embryo development.

Fall Prevention Self-Assessments Via Mobile 3D Visualization Technologies: Community Dwelling Older Adults' Perceptions of Opportunities and Challenges.

PubMed

Hamm, Julian; Money, Arthur; Atwal, Anita

2017-06-19

In the field of occupational therapy, the assistive equipment provision process (AEPP) is a prominent preventive strategy used to promote independent living and to identify and alleviate fall risk factors via the provision of assistive equipment within the home environment. Current practice involves the use of paper-based forms that include 2D measurement guidance diagrams that aim to communicate the precise points and dimensions that must be measured in order to make AEPP assessments. There are, however, issues such as "poor fit" of equipment due to inaccurate measurements taken and recorded, resulting in more than 50% of equipment installed within the home being abandoned by patients. This paper presents a novel 3D measurement aid prototype (3D-MAP) that provides enhanced measurement and assessment guidance to patients via the use of 3D visualization technologies. The purpose of this study was to explore the perceptions of older adults with regard to the barriers and opportunities of using the 3D-MAP application as a tool that enables patient self-delivery of the AEPP. Thirty-three community-dwelling older adults participated in interactive sessions with a bespoke 3D-MAP application utilizing the retrospective think-aloud protocol and semistructured focus group discussions. The system usability scale (SUS) questionnaire was used to evaluate the application's usability. Thematic template analysis was carried out on the SUS item discussions, think-aloud, and semistructured focus group data. The quantitative SUS results revealed that the application may be described as having "marginal-high" and "good" levels of usability, along with strong agreement with items relating to the usability (P=.004) and learnability (P<.001) of the application. Four high-level themes emerged from think-aloud and focus groups discussions: (1) perceived usefulness (PU), (2) perceived ease of use (PEOU), (3) application use (AU) and (4) self-assessment (SA). The application was seen as a useful tool to enhance visualization of measurement guidance and also to promote independent living, ownership of care, and potentially reduce waiting times. Several design and functionality recommendations emerged from the study, such as a need to manipulate the view and position of the 3D furniture models, and a need for clearer visual prompts and alternative keyboard interface for measurement entry. Participants perceived the 3D-MAP application as a useful tool that has the potential to make significant improvements to the AEPP, not only in terms of accuracy of measurement, but also by potentially enabling older adult patients to carry out the data collection element of the AEPP themselves. Further research is needed to further adapt the 3D-MAP application in line with the study outcomes and to establish its clinical utility with regards to effectiveness, efficiency, accuracy, and reliability of measurements that are recorded using the application and to compare it with 2D measurement guidance leaflets. ©Julian Hamm, Arthur Money, Anita Atwal. Originally published in JMIR Human Factors (http://humanfactors.jmir.org), 19.06.2017.

Biologic Monitoring to Characterize Organophosphorus Pesticide Exposure among Children and Workers: An Analysis of Recent Studies in Washington State

PubMed Central

Fenske, Richard A.; Lu, Chensheng; Curl, Cynthia L.; Shirai, Jeffry H.; Kissel, John C.

2005-01-01

We examined findings from five organophosphorus pesticide biomonitoring studies conducted in Washington State between 1994 and 1999. We compared urinary dimethylthiophosphate (DMTP) concentrations for all study groups and composite dimethyl alkylphosphate (DMAP) concentrations for selected groups. Children of pesticide applicators had substantially higher metabolite levels than did Seattle children and farmworker children (median DMTP, 25 μg/L; p < 0.0001). Metabolite levels of children living in agricultural communities were elevated during periods of crop spraying. Median DMTP concentrations for Seattle children and farmworker children did not differ significantly (6.1 and 5.8 μg/L DMTP, respectively; p = 0.73); however, the DMAP concentrations were higher for Seattle children than for farmworker children (117 and 87 nmol/L DMAP, respectively; p = 0.007). DMTP concentrations of U.S. children 6–11 years of age (1999–2000 National Health and Nutrition Examination Survey population) were higher than those of Seattle children and farmworker children at the 75th, 90th, and 95th percentiles. DMTP concentrations for workers actively engaged in apple thinning were 50 times higher than DMTP concentrations for farmworkers sampled outside of peak exposure periods. We conclude that workers who have direct contact with pesticides should continue to be the focus of public health interventions and that elevated child exposures in agricultural communities may occur during active crop-spraying periods and from living with a pesticide applicator. Timing of sample collection is critical for the proper interpretation of pesticide biomarkers excreted relatively soon after exposure. We surmise that differences in dietary exposure can explain the similar exposures observed among farmworker children, children living in the Seattle metropolitan area, and children sampled nationally. PMID:16263526

3D-Mapping of Dolomitized Structures in Lower Cambrian Phosphorites

NASA Astrophysics Data System (ADS)

Hippler, Dorothee; Stammeier, Jessica A.; Brunner, Roland; Rosc, Jördis; Franz, Gerhard; Dietzel, Martin

2016-04-01

Dolomitization is a widespread phenomenon in ancient sedimentary rocks, particularly close to the Precambrian-Cambrian boundary. Dolomite can form in synsedimentary or hydrothermal environments, preferentially via the replacement of solid carbonate precursor phases. Synsedimentary dolomite formation is often associated with microbial activity, such as bacterial sulfate reduction or methanogenesis. In this study, we investigate dolomitic phosphorites from the Lowermost Cambrian Tal Group, Mussoori Syncline, Lesser Himalaya, India, using micro-CT 3D-mapping, in order to unravel the complex diagenetic history of the rocks. The selected sample shows alternating layering of phosphatic mudstones and sparitic dolostone, in which brecciated layers of phosphorite or phosphatic mudstones are immersed in a dolomite-rich matrix. Lamination occurs on a sub-millimetre scale, with lamination sometimes wavy to crinkly. This fabric is interpreted as former microbial mats, providing the environment for early diagenetic phosphatization. Preliminary electron backscatter imaging with scanning microscopy revealed that dolomite crystals often occur in spherical to ellipsoidal structures, typically with a high porosity. This dolomite is associated with botryoidal apatite, organic matter and small amounts of calcite. Micro-CT 3D-mappings reveal that dolomite structures are cigar-shaped, elongated and up to 600 μm long. They are further arranged in a Mikado-like oriented framework spanning a layer thickness of a few millimetres. Analyses of ambient pore space, with similar elongated outlines and filled with organic matter, suggest a potential coherence of ambient pore space and shape of the dolomite structures. Allowing for other associated mineral phases, such as pyrite and silicates, and their spatial distribution, the present approach can be used to unravel distinct diagenetic reaction pathways, and might thus constrain the proxy potential of these Lower Cambrian dolomitic phosphorites to reconstruct ambient environmental at the time of deposition.

Effectiveness of intramuscularly administered cyanide antidotes and the rate of methemoglobin formation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vick, J.A.; Von Bredow, J.D.

1993-05-13

Successful first aid therapy for cyanide intoxication is dependent upon the immediate administration of antidotes which directly or indirectly interact with the cyanide ion to remove it from circulation. Exceptionally rapid methemoglobin formers (hydroxylamine hydrochloride 'HA) and Dimethylaminophenol (DMAP) are usually able to prevent the lethal effect of cyanide following intramuscular injections in doses sufficient to induce 20% methemoglobin (HA = 20 mg/kg and DMAP= 2 mg/kg). Sodium nitrite, the methemoglobin inducer approved by the FDA and is available for military use, must be administered by intravenous infusion since it is not an effective cyanide antidote by the intramuscular route.more » In the normal un-intoxicated animal an intramuscular injection of 20 mg/kg sodium nitrite will form 20% methemoglobin at a rapid rate; however, in the presence of acute cyanide intoxication the associated severe bradycardia appears to limit the rate of absorption of sodium nitrite from the intramuscular site which prevents the rapid formation of sufficient methemoglobin to counteract cyanide intoxication.« less

The Design and Usage of the New Data Management Features in NASTRAN

NASA Technical Reports Server (NTRS)

Pamidi, P. R.; Brown, W. K.

1984-01-01

Two new data management features are installed in the April 1984 release of NASTRAN. These two features are the Rigid Format Data Base and the READFILE capability. The Rigid Format Data Base is stored on external files in card image format and can be easily maintained and expanded by the use of standard text editors. This data base provides the user and the NASTRAN maintenance contractor with an easy means for making changes to a Rigid Format or for generating new Rigid Formats without unnecessary compilations and link editing of NASTRAN. Each Rigid Format entry in the data base contains the Direct Matrix Abstraction Program (DMAP), along with the associated restart, DMAP sequence subset and substructure control flags. The READFILE capability allows an user to reference an external secondary file from the NASTRAN primary input file and to read data from this secondary file. There is no limit to the number of external secondary files that may be referenced and read.

Combining Acceleration and Displacement Dependent Modal Frequency Responses Using an MSC/NASTRAN DMAP Alter

NASA Technical Reports Server (NTRS)

Barnett, Alan R.; Widrick, Timothy W.; Ludwiczak, Damian R.

1996-01-01

Solving for dynamic responses of free-free launch vehicle/spacecraft systems acted upon by buffeting winds is commonly performed throughout the aerospace industry. Due to the unpredictable nature of this wind loading event, these problems are typically solved using frequency response random analysis techniques. To generate dynamic responses for spacecraft with statically-indeterminate interfaces, spacecraft contractors prefer to develop models which have response transformation matrices developed for mode acceleration data recovery. This method transforms spacecraft boundary accelerations and displacements into internal responses. Unfortunately, standard MSC/NASTRAN modal frequency response solution sequences cannot be used to combine acceleration- and displacement-dependent responses required for spacecraft mode acceleration data recovery. External user-written computer codes can be used with MSC/NASTRAN output to perform such combinations, but these methods can be labor and computer resource intensive. Taking advantage of the analytical and computer resource efficiencies inherent within MS C/NASTRAN, a DMAP Alter has been developed to combine acceleration- and displacement-dependent modal frequency responses for performing spacecraft mode acceleration data recovery. The Alter has been used successfully to efficiently solve a common aerospace buffeting wind analysis.

The Contrasting Alkylations of 4-(Dimethylaminomethyl)pyridine and 4-(Dimethylamino)pyridine: An Organic Chemistry Experiment

ERIC Educational Resources Information Center

Jantzi, Kevin L.; Wiltrakis, Susan; Wolf, Lauren; Weber, Anna; Cardinal, Josh; Krieter, Katie

2011-01-01

A critical factor for the increased nucleophilicity of the pyridine nitrogen in 4-(dimethylamino)pyridine (DMAP) is electron donation via resonance from the amino group into the aromatic ring that increases electron density on the pyridine nitrogen. To explore how important this resonance effect is, 4-(dimethylaminomethyl)pyridine (DMAMP) was…

An enhancement of NASTRAN for the seismic analysis of structures. [nuclear power plants

NASA Technical Reports Server (NTRS)

Burroughs, J. W.

1980-01-01

New modules, bulk data cards and DMAP sequence were added to NASTRAN to aid in the seismic analysis of nuclear power plant structures. These allow input consisting of acceleration time histories and result in the generation of acceleration floor response spectra. The resulting system contains numerous user convenience features, as well as being reasonably efficient.

Acylation, Diastereoselective Alkylation, and Cleavage of an Oxazolidinone Chiral Auxiliary: A Multistep Asymmetric Synthesis Experiment for Advanced Undergraduates

ERIC Educational Resources Information Center

Smith, Thomas E.; Richardson, David P.; Truran, George A.; Belecki, Katherine; Onishi, Megumi

2008-01-01

An introduction to the concepts and experimental techniques of diastereoselective synthesis using a chiral auxiliary is described. The 4-benzyl-2-oxazolidinone chiral auxiliary developed by Evans is acylated with propionic anhydride under mild conditions using DMAP as an acyl transfer catalyst. Deprotonation with NaN(TMS)[subscript 2] at -78…

Closed-form Static Analysis with Inertia Relief and Displacement-Dependent Loads Using a MSC/NASTRAN DMAP Alter

NASA Technical Reports Server (NTRS)

Barnett, Alan R.; Widrick, Timothy W.; Ludwiczak, Damian R.

1995-01-01

Solving for the displacements of free-free coupled systems acted upon by static loads is commonly performed throughout the aerospace industry. Many times, these problems are solved using static analysis with inertia relief. This solution technique allows for a free-free static analysis by balancing the applied loads with inertia loads generated by the applied loads. For some engineering applications, the displacements of the free-free coupled system induce additional static loads. Hence, the applied loads are equal to the original loads plus displacement-dependent loads. Solving for the final displacements of such systems is commonly performed using iterative solution techniques. Unfortunately, these techniques can be time-consuming and labor-intensive. Since the coupled system equations for free-free systems with displacement-dependent loads can be written in closed-form, it is advantageous to solve for the displacements in this manner. Implementing closed-form equations in static analysis with inertia relief is analogous to implementing transfer functions in dynamic analysis. Using a MSC/NASTRAN DMAP Alter, displacement-dependent loads have been included in static analysis with inertia relief. Such an Alter has been used successfully to solve efficiently a common aerospace problem typically solved using an iterative technique.

Identification of Cyclin A Binders with a Fluorescent Peptide Sensor.

PubMed

Pazos, Elena; Mascareñas, José L; Vázquez, M Eugenio

2016-01-01

A peptide sensor that integrates the 4-dimethylaminophthalimide (4-DMAP) fluorophore in a short cyclin A binding sequence displays a large fluorescence emission increase upon interacting with the cyclin A Binding Groove (CBG). Competitive displacement assays of this probe allow the straightforward identification of peptides that interact with the CBG, which could potentially block the recognition of CDK/cyclin A kinase substrates.

NASTRAN thermal analyzer: Theory and application including a guide to modeling engineering problems, volume 2. [sample problem library guide

NASA Technical Reports Server (NTRS)

Jackson, C. E., Jr.

1977-01-01

A sample problem library containing 20 problems covering most facets of Nastran Thermal Analyzer modeling is presented. Areas discussed include radiative interchange, arbitrary nonlinear loads, transient temperature and steady-state structural plots, temperature-dependent conductivities, simulated multi-layer insulation, and constraint techniques. The use of the major control options and important DMAP alters is demonstrated.

Rational design of a cyclin A fluorescent peptide sensor.

PubMed

Pazos, Elena; Pérez, Miguel; Gutiérrez-de-Terán, Hugo; Orzáez, Mar; Guevara, Tatiana; Mascareñas, José L; Vázquez, M Eugenio

2011-10-26

We report the design and development of a fluorescent sensor specifically designed to target cyclin A, a protein that plays a key role in the regulation of the cell cycle. Computational studies provide a molecular picture that explains the observed emission increase, suggesting that the 4-DMAP fluorophore in the peptide is protected from the bulk solvent when inserted into the hydrophobic binding groove of cyclin A.

Synthesis and antiproliferative activity of a cyclic analog of dolastatin 10.

PubMed

Poncet, J; Hortala, L; Busquet, M; Guéritte-Voegelein, F; Thoret, S; Pierré, A; Atassi, G; Jouin, P

1998-10-20

A cyclic analog of the natural antiproliferative compound dolastatin 10 was synthesized by introducing an ester link between the N- and C-terminal residues which were modified accordingly. The final macrolactonization was performed by using isopropenyl chloroformate and DMAP as reagents. This analog exhibits submicromolar antiproliferative activity against the L1210 and HT29 cell lines and inhibits in vitro tubulin polymerization (IC50, 39 microM).

Basic studies on the pyrolysis of lignin compounds

Treesearch

Byung-ho Hwang

2003-01-01

By pyrolyzing lignin model compounds 1-lV at 315°C, an investigation was carried out with some results. In the pyrolysis of lignin model compound I and 11, 0.47 mol of guaiacol, 0.57 mol of dimethoxyphenol (DMP), and 0.12 and 0.23 mol of dimethoxyaceton ophenone (DMAP) were produced respectively. In the pyrolysis of lignin model compound lll and lV, 0.26 mol of...

A DMAP Program for the Selection of Accelerometer Locations in MSC/NASTRAN

NASA Technical Reports Server (NTRS)

Peck, Jeff; Torres, Isaias

2004-01-01

A new program for selecting sensor locations has been written in the DMAP (Direct Matrix Abstraction Program) language of MSC/NASTRAN. The program implements the method of Effective Independence for selecting sensor locations, and is executed within a single NASTRAN analysis as a "rigid format alter" to the normal modes solution sequence (SOL 103). The user of the program is able to choose among various analysis options using Case Control and Bulk Data entries. Algorithms tailored for the placement of both uni-axial and tri- axial accelerometers are available, as well as several options for including the model s mass distribution into the calculations. Target modes for the Effective Independence analysis are selected from the MSC/NASTRAN ASET modes calculated by the "SOL 103" solution sequence. The initial candidate sensor set is also under user control, and is selected from the ASET degrees of freedom. Analysis results are printed to the MSCINASTRAN output file (*.f06), and may include the current candidate sensors set, and their associated Effective Independence distribution, at user specified iteration intervals. At the conclusion of the analysis, the model is reduced to the final sensor set, and frequencies and orthogonality checks are printed. Example results are given for a pre-test analysis of NASA s five-segment solid rocket booster modal test.

Transient analysis mode participation for modal survey target mode selection using MSC/NASTRAN DMAP

NASA Technical Reports Server (NTRS)

Barnett, Alan R.; Ibrahim, Omar M.; Sullivan, Timothy L.; Goodnight, Thomas W.

1994-01-01

Many methods have been developed to aid analysts in identifying component modes which contribute significantly to component responses. These modes, typically targeted for dynamic model correlation via a modal survey, are known as target modes. Most methods used to identify target modes are based on component global dynamic behavior. It is sometimes unclear if these methods identify all modes contributing to responses important to the analyst. These responses are usually those in areas of hardware design concerns. One method used to check the completeness of target mode sets and identify modes contributing significantly to important component responses is mode participation. With this method, the participation of component modes in dynamic responses is quantified. Those modes which have high participation are likely modal survey target modes. Mode participation is most beneficial when it is used with responses from analyses simulating actual flight events. For spacecraft, these responses are generated via a structural dynamic coupled loads analysis. Using MSC/NASTRAN DMAP, a method has been developed for calculating mode participation based on transient coupled loads analysis results. The algorithm has been implemented to be compatible with an existing coupled loads methodology and has been used successfully to develop a set of modal survey target modes.

Design of experiments as a tool for LC-MS/MS method development for the trace analysis of the potentially genotoxic 4-dimethylaminopyridine impurity in glucocorticoids.

PubMed

Székely, Gy; Henriques, B; Gil, M; Ramos, A; Alvarez, C

2012-11-01

The present study reports on a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method development strategy supported by design of experiments (DoE) for the trace analysis of 4-dimethylaminopyridine (DMAP). The conventional approaches for development of LC-MS/MS methods are usually via trial and error, varying intentionally the experimental factors which is time consuming and interactions between experimental factors are not considered. The LC factors chosen for the DoE study include flow (F), gradient (G) and injection volume (V(inj)) while cone voltage (E(con)) and collision energy (E(col)) were chosen as MS parameters. All of the five factors were studied simultaneously. The method was optimized with respect to four responses: separation of peaks (Sep), peak area (A(peak)), length of the analysis (T) and the signal to noise ratio (S/N). A quadratic model, namely central composite face (CCF) featuring 29 runs was used instead of a less powerful linear model since the increase in the number of injections was insignificant. In order to determine the robustness of the method a new set of DoE experiments was carried out applying robustness around the optimal conditions was evaluated applying a fractional factorial of resolution III with 11 runs, wherein additional factors - such as column temperature and quadrupole resolution - were considered. The method utilizes a Phenomenex Gemini NX C-18 HPLC analytical column with electrospray ionization and a triple quadrupole mass detector in multiple reaction monitoring (MRM) mode, resulting in short analyses with a 10min runtime. Drawbacks of derivatization, namely incomplete reaction and time consuming sample preparation, have been avoided and the change from SIM to MRM mode resulted in increased sensitivity and lower LOQ. The DoE method development strategy led to a method allowing the trace analysis of DMAP at 0.5 ng/ml absolute concentration which corresponds to a 0.1 ppm limit of quantification in 5mg/ml mometasone furoate glucocorticoid. The obtained method was validated in a linear range of 0.1-10 ppm and presented a %RSD of 0.02% for system precision. Regarding DMAP recovery in mometasone furoate, spiked samples produced %recoveries between 83 and 113% in the range of 0.1-2 ppm. Copyright © 2012 Elsevier B.V. All rights reserved.

X-ray Absorption Spectroscopy Combined with Time-Dependent Density Functional Theory Elucidates Differential Substitution Pathways of Au(I) and Au(III) with Zinc Fingers.

PubMed

Abbehausen, Camilla; de Paiva, Raphael Enoque Ferraz; Bjornsson, Ragnar; Gomes, Saulo Quintana; Du, Zhifeng; Corbi, Pedro Paulo; Lima, Frederico Alves; Farrell, Nicholas

2018-01-02

A combination of two elements' (Au, Zn) X-ray absorption spectroscopy (XAS) and time-dependent density functional theory (TD-DFT) allowed the elucidation of differential substitution pathways of Au(I) and Au(III) compounds reacting with biologically relevant zinc fingers (ZnFs). Gold L 3 -edge XAS probed the interaction of gold and the C-terminal Cys 2 HisCys finger of the HIV-1 nucleocapsid protein NCp7, and the Cys 2 His 2 human transcription factor Sp1. The use of model compounds helped assign oxidation states and the identity of the gold-bound ligands. The computational studies accurately reproduced the experimental XAS spectra and allowed the proposition of structural models for the interaction products at early time points. The direct electrophilic attack on the ZnF by the highly thiophilic Au(I) resulted in a linear P-Au-Cys coordination sphere after zinc ejection whereas for the Sp1, loss of PEt 3 results in linear Cys-Au-Cys or Cys-Au-His arrangements. Reactions with Au(III) compounds, on the other hand, showed multiple binding modes. Prompt reaction between [AuCl(dien)] 2+ and [Au(dien)(DMAP)] 3+ with Sp1 showed a partially reduced Au center and a final linear His-Au-His coordination. Differently, in the presence of NCp7, [AuCl(dien)] 2+ readily reduces to Au(I) and changes from square-planar to linear geometry with Cys-Au-His coordination, while [Au(dien)(DMAP)] 3+ initially maintains its Au(III) oxidation state and square-planar geometry and the same first coordination sphere. The latter is the first observation of a "noncovalent" interaction of a Au(III) complex with a zinc finger and confirms early hypotheses that stabilization of Au(III) occurs with N-donor ligands. Modification of the zinc coordination sphere, suggesting full or partial zinc ejection, is observed in all cases, and for [Au(dien)(DMAP)] 3+ this represents a novel mechanism for nucleocapsid inactivation. The combination of XAS and TD-DFT presents the first direct experimental observation that not only compound reactivity, but also ZnF core specificity, can be modulated on the basis of the coordination sphere of Au(III) compounds.

Ad E1A 243R oncoprotein promotes association of proto-oncogene product MYC with the NuA4/Tip60 complex via the E1A N-terminal repression domain.

PubMed

Zhao, Ling-Jun; Loewenstein, Paul M; Green, Maurice

2016-12-01

The adenovirus E1A 243R oncoprotein targets TRRAP, a scaffold protein that assembles histone acetyltransferase (HAT) complexes, such as the NuA4/Tip60 complex which mediates transcriptional activity of the proto-oncogene MYC and helps determine the cancer cell phenotype. How E1A transforms cells through TRRAP remains obscure. We performed proteomic analysis with the N-terminal transcriptional repression domain of E1A 243R (E1A 1-80) and showed that E1A 1-80 interacts with TRRAP, p400, and three other members of the NuA4 complex - DMAP1, RUVBL1 and RUVBL2 - not previously shown to associate with E1A 243R. E1A 1-80 interacts with these NuA4 components and MYC through the E1A TRRAP-targeting domain. E1A 243R association with the NuA4 complex was demonstrated by co-immunoprecipitation and analysis with DMAP1, Tip60, and MYC. Significantly, E1A 243R promotes association of MYC/MAX with the NuA4/Tip60 complex, implicating the importance of the MYC/NuA4 pathway in cellular transformation by both MYC and E1A. Copyright © 2016 Elsevier Inc. All rights reserved.

Serum leveis of inflammatory markers in type 2 diabetes patients with chronic periodontitis

PubMed Central

LONGO, Priscila Larcher; ARTESE, Hilana Paula Carillo; RABELO, Marianade Sousa; KAWAMOTO, Dione; FOZ, Adriana Moura; ROMITO, Giuseppe Alexandre; DIB, Sérgio Atala; MAYER, Marcia Pinto Alves

2014-01-01

Diabetes has been associated with periodontitis, but the mechanisms through which periodontal diseases affect the metabolic control remain unclear. Objective This study aimed to evaluate serum leveis of inflammatory markers, IL-8, IL-6 and monocyte chemoattractant protein 1 (MCP-1), in type 2 diabetic patients in the presence of chronic periodontitis. Material and Methods Forty two individuals were enrolled in this study and assigned to one of five groups: diabetes mellitus with inadequate glycemic control and periodontitis (DMI+P, n = 10), diabetes mellitus with adequate glycemic control and periodontitis (DMA+P, n = 10), diabetes mellitus without periodontitis (DM, n = 10), periodontitis without diabetes (P, n=6), and neither diabetes nor periodontitis (H, n = 6). Periodontal clinical examination included visible plaque index (PL), gingival bleeding index (GB), probing depth (PD), attachment level (AL) and bleeding on probing (BP). Glycemic control was evaluated by serum concentration of glycated hemoglobin (HbAlc). Inflammatory serum markers IL-8, IL-6 and (MCP-1) were measured by ELISA. Results DMI+P and DMA+P groups presented higher PD (p=0.025) and AL (p=0.003) values when compared to the P group. There were no significant differences among groups for IL-6, IL-8 and MCP-1 serum levels. Conclusions Although periodontitis was more severe in diabetic patients, the serum levels of the investigated inflammatory markers did not differ among the groups. PMID:24676580

Predictors of exposure to organophosphate pesticides in schoolchildren in the Province of Talca, Chile.

PubMed

Muñoz-Quezada, María Teresa; Iglesias, Verónica; Lucero, Boris; Steenland, Kyle; Barr, Dana Boyd; Levy, Karen; Ryan, P Barry; Alvarado, Sergio; Concha, Carlos

2012-10-15

Few data exist in Latin America concerning the association between organophosphate (OP) urinary metabolites and the consumption of fruits and vegetables and other exposure risk variables in schoolchildren. We collected samples of urine from 190 Chilean children aged 6-12 years, fruits and vegetables, water and soil from schools and homes, and sociodemographic data through a questionnaire. We measured urinary dialkylphosphate (DAP) OP metabolites and OP pesticide residues in food consumed by these 190 children during two seasons: December 2010 (summer) and May 2011 (fall). We analyzed the relationship between urinary DAP concentrations and pesticide residues in food, home pesticide use, and residential location. Diethylalkylphosphates (DEAP) and dimethylalkylphosphates (DMAP) were detected in urine in 76% and 27% of the samples, respectively. Factors associated with urinary DEAP included chlorpyrifos in consumed fruits (p<0.0001), urinary creatinine (p<0.0001), rural residence (p=0.02) and age less than 9 years (p=0.004). Factors associated with urinary DMAP included the presence of phosmet residues in fruits (p<0.0001), close proximity to a farm (p=0.002), home fenitrothion use (p=0.009), and season (p<0.0001). Urinary DAP levels in Chilean school children were high compared to previously reported studies. The presence of chlorpyrifos and phosmet residues in fruits was the major factor predicting urinary DAP metabolite concentrations in children. Copyright © 2012 Elsevier Ltd. All rights reserved.

MSC/NASTRAN DMAP Alter Used for Closed-Form Static Analysis With Inertia Relief and Displacement-Dependent Loads

NASA Technical Reports Server (NTRS)

1996-01-01

Solving for the displacements of free-free coupled systems acted upon by static loads is a common task in the aerospace industry. Often, these problems are solved by static analysis with inertia relief. This technique allows for a free-free static analysis by balancing the applied loads with the inertia loads generated by the applied loads. For some engineering applications, the displacements of the free-free coupled system induce additional static loads. Hence, the applied loads are equal to the original loads plus the displacement-dependent loads. A launch vehicle being acted upon by an aerodynamic loading can have such applied loads. The final displacements of such systems are commonly determined with iterative solution techniques. Unfortunately, these techniques can be time consuming and labor intensive. Because the coupled system equations for free-free systems with displacement-dependent loads can be written in closed form, it is advantageous to solve for the displacements in this manner. Implementing closed-form equations in static analysis with inertia relief is analogous to implementing transfer functions in dynamic analysis. An MSC/NASTRAN (MacNeal-Schwendler Corporation/NASA Structural Analysis) DMAP (Direct Matrix Abstraction Program) Alter was used to include displacement-dependent loads in static analysis with inertia relief. It efficiently solved a common aerospace problem that typically has been solved with an iterative technique.

Atomic layer deposition of Cu( i ) oxide films using Cu( ii ) bis(dimethylamino-2-propoxide) and water

DOE Office of Scientific and Technical Information (OSTI.GOV)

Avila, J. R.; Peters, A. W.; Li, Zhanyong

2017-01-01

To grow fIlms of Cu2O, bis-(dimethylamino-2-propoxide)Cu(II), or Cu(dmap), is used as an atomic layer deposition precursor using only water vapor as a co-reactant. Between 110 and 175 °C, a growth rate of 0.12 ± 0.02 Å per cycle was measured using an in situ quartz crystal microbalance (QCM). X-ray photoelectron spectroscopy (XPS) confirms the growth of metal– oxide films featuring Cu(I).

Channeling Nanoparticles for Detection and Targeted Treatment of Breast Cancerous Lesions

DTIC Science & Technology

2011-10-01

µmoles, or 16.5mg) of PEG 2000. Dimethylaminopyridine (DMAP, 0.5 molar equivalents) and 1 -Ethyl- 3 - [ 3 - dimethylaminopropyl ]carbodiimide (EDC...control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1 . REPORT DATE (DD-MM-YYYY) 2. REPORT TYPE 3 . DATES COVERED (From - To) 4. TITLE...OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1 . REPORT DATE (DD-MM-YYYY) 14-10-2011 2. REPORT TYPE Final 3 . DATES

Dynamic analysis using superelements for a large helicopter model

NASA Technical Reports Server (NTRS)

Patel, M. P.; Shah, L. C.

1978-01-01

Using superelements (substructures), modal and frequency response analysis was performed for a large model of the Advanced Attack Helicopter developed for the U.S. Army. Whiffletree concept was employed so that the residual structure along with the various superelements could be represented as beam-like structures for economical and accurate dynamic analysis. A very large DMAP alter to the rigid format was developed so that the modal analysis, the frequency response, and the strain energy in each component could be computed in the same run.

49 CFR 552.6 - Technical review.

Code of Federal Regulations, 2010 CFR

2010-10-01

... § 552.6 Technical review. The appropriate Associate Administrator conducts a technical review of the petition. The technical review may consist of an analysis of the material submitted, together with... 49 Transportation 6 2010-10-01 2010-10-01 false Technical review. 552.6 Section 552.6...

49 CFR 552.6 - Technical review.

Code of Federal Regulations, 2011 CFR

2011-10-01

... § 552.6 Technical review. The appropriate Associate Administrator conducts a technical review of the petition. The technical review may consist of an analysis of the material submitted, together with... 49 Transportation 6 2011-10-01 2011-10-01 false Technical review. 552.6 Section 552.6...

Varying the Lewis base coordination of the Y2N2 core in the reduced dinitrogen complexes {[(Me3Si)2N]2(L)Y}2(μ-η2:η2-N2) (L = benzonitrile, pyridines, triphenylphosphine oxide, and trimethylamine N-oxide).

PubMed

Corbey, Jordan F; Farnaby, Joy H; Bates, Jefferson E; Ziller, Joseph W; Furche, Filipp; Evans, William J

2012-07-16

The effect of the neutral donor ligand, L, on the Ln(2)N(2) core in the (N═N)(2-) complexes, [A(2)(L)Ln](2)(μ-η(2):η(2)-N(2)) (Ln = Sc, Y, lanthanide; A = monoanion; L = neutral ligand), is unknown since all of the crystallographically characterized examples were obtained with L = tetrahydrofuran (THF). To explore variation in L, displacement reactions between {[(Me(3)Si)(2)N](2)(THF)Y}(2)(μ-η(2):η(2)-N(2)), 1, and benzonitrile, pyridine (py), 4-dimethylaminopyridine (DMAP), triphenylphosphine oxide, and trimethylamine N-oxide were investigated. THF is displaced by all of these ligands to form {[(Me(3)Si)(2)N](2)(L)Y}(2)(μ-η(2):η(2)-N(2)) complexes (L = PhCN, 2; py, 3; DMAP, 4; Ph(3)PO, 5; Me(3)NO, 6) that were fully characterized by analytical, spectroscopic, density functional theory, and X-ray crystallographic methods. The crystal structures of the Y(2)N(2) cores in 2-5 are similar to that in 1 with N-N bond distances between 1.255(3) Å and 1.274(3) Å, but X-ray analysis of the N-N distance in 6 shows it to be shorter: 1.198(3) Å.

Cooperative catalysis: electron-rich Fe-H complexes and DMAP, a successful "joint venture" for ultrafast hydrogen production.

PubMed

Rommel, Susanne; Hettmanczyk, Lara; Klein, Johannes E M N; Plietker, Bernd

2014-08-01

A series of defined iron-hydrogen complexes was prepared in a straightforward one-pot approach. The structure and electronic properties of such complexes were investigated by means of quantum-chemical analysis. These new complexes were then applied in the dehydrogenative silylation of methanol. The complex (dppp)(CO)(NO)FeH showed a remarkable activity with a TOF of more than 600 000 h(-1) of pure hydrogen gas within seconds. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

New coumarin carboxylates having trifluoromethyl, diethylamino and morpholino terminal groups: Synthesis and mesomorphic characterisations

NASA Astrophysics Data System (ADS)

Srinivasa, Hosapalya Thimmaiah; Harishkumar, Hosanagara Narayana; Palakshamurthy, Bandrehalli Siddagangappa

2017-03-01

New set of trifluromethyl, diethylamino and morpholino derived coumarin compounds were prepared by reacting various coumarin 3-carboxylic acids with various phenyl esters with peripheral alkyl, ester and polar cyano moieties in the presence of EDC.HCl/DMAP as esterification agent. The chemical structures of new coumarin derivatives were confirmed by standard spectroscopic techniques and mesomorphic behaviours were established by polarised optical microscopy (POM) and differential scanning calorimetry (DSC). Trifluoromethane and morpholino derivatives show SmA/Nematic phase, while diethylamino derivatives did not show liquid crystalline property.

A numerically efficient finite element hydroelastic analysis. Volume 2: Implementation in NASTRAN, part 1

NASA Technical Reports Server (NTRS)

Coppolino, R. N.

1974-01-01

Details are presented of the implementation of the new formulation into NASTRAN including descriptions of the DMAP statements required for conversion of the program and details pertaining to problem definition and bulk data considerations. Details of the current 1/8-scale space shuttle external tank mathematical model, numerical results and analysis/test comparisons are also presented. The appendices include a description and listing of a FORTRAN program used to develop harmonic transformation bulk data (multipoint constraint statements) and sample bulk data information for a number of hydroelastic problems.

Engineering Technical Review Planning Briefing

NASA Technical Reports Server (NTRS)

Gardner, Terrie

2012-01-01

The general topics covered in the engineering technical planning briefing are 1) overviews of NASA, Marshall Space Flight Center (MSFC), and Engineering, 2) the NASA Systems Engineering(SE) Engine and its implementation , 3) the NASA Project Life Cycle, 4) MSFC Technical Management Branch Services in relation to the SE Engine and the Project Life Cycle , 5) Technical Reviews, 6) NASA Human Factor Design Guidance , and 7) the MSFC Human Factors Team. The engineering technical review portion of the presentation is the primary focus of the overall presentation and will address the definition of a design review, execution guidance, the essential stages of a technical review, and the overall review planning life cycle. Examples of a technical review plan content, review approaches, review schedules, and the review process will be provided and discussed. The human factors portion of the presentation will focus on the NASA guidance for human factors. Human factors definition, categories, design guidance, and human factor specialist roles will be addressed. In addition, the NASA Systems Engineering Engine description, definition, and application will be reviewed as background leading into the NASA Project Life Cycle Overview and technical review planning discussion.

75 FR 61228 - Board Meeting: Technical Lessons Gained From High-Level Nuclear Waste Disposal Efforts

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-04

... NUCLEAR WASTE TECHNICAL REVIEW BOARD Board Meeting: Technical Lessons Gained From High-Level... Waste Policy Amendments Act of 1987, the U.S. Nuclear Waste Technical Review Board will meet in Dulles... of Energy on technical issues and to review the technical validity of DOE activities related to...

An Improved System for Generation of Diploid Cloned Porcine Embryos Using Induced Pluripotent Stem Cells Synchronized to Metaphase.

PubMed

Kim, Eunhye; Zheng, Zhong; Jeon, Yubyeol; Jin, Yong-Xun; Hwang, Seon-Ung; Cai, Lian; Lee, Chang-Kyu; Kim, Nam-Hyung; Hyun, Sang-Hwan

2016-01-01

Pigs provide outstanding models of human genetic diseases due to their striking similarities with human anatomy, physiology and genetics. Although transgenic pigs have been produced using genetically modified somatic cells and nuclear transfer (SCNT), the cloning efficiency was extremely low. Here, we report an improved method to produce diploid cloned embryos from porcine induced pluripotent stem cells (piPSCs), which were synchronized to the G2/M stage using a double blocking method with aphidicolin and nocodazole. The efficiency of this synchronization method on our piPSC lines was first tested. Then, we modified our traditional SCNT protocol to find a workable protocol. In particular, the removal of a 6DMAP treatment post-activation enhanced the extrusion rate of pseudo-second-polar bodies (p2PB) (81.3% vs. 15.8%, based on peak time, 4hpa). Moreover, an immediate activation method yielded significantly more blastocysts than delayed activation (31.3% vs. 16.0%, based on fused embryos). The immunofluorescent results confirmed the effect of the 6DMAP treatment removal, showing remarkable p2PB extrusion during a series of nuclear transfer procedures. The reconstructed embryos from metaphase piPSCs with our modified protocol demonstrated normal morphology at 2-cell, 4-cell and blastocyst stages and a high rate of normal karyotype. This study demonstrated a new and efficient way to produce viable cloned embryos from piPSCs when synchronized to the G2/M phase of the cell cycle, which may lead to opportunities to produce cloned pigs from piPSCs more efficiently.

24 CFR 902.68 - Technical review of results of PHAS Indicators #1 or #4.

Code of Federal Regulations, 2010 CFR

2010-04-01

... both reviews, a request for technical review must be submitted in writing to the Director of the Real... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Technical review of results of PHAS... HOUSING AND URBAN DEVELOPMENT PUBLIC HOUSING ASSESSMENT SYSTEM PHAS Scoring § 902.68 Technical review of...

JPL-ANTOPT antenna structure optimization program

NASA Technical Reports Server (NTRS)

Strain, D. M.

1994-01-01

New antenna path-length error and pointing-error structure optimization codes were recently added to the MSC/NASTRAN structural analysis computer program. Path-length and pointing errors are important measured of structure-related antenna performance. The path-length and pointing errors are treated as scalar displacements for statics loading cases. These scalar displacements can be subject to constraint during the optimization process. Path-length and pointing-error calculations supplement the other optimization and sensitivity capabilities of NASTRAN. The analysis and design functions were implemented as 'DMAP ALTERs' to the Design Optimization (SOL 200) Solution Sequence of MSC-NASTRAN, Version 67.5.

Alkylating Derivatives of Vitamin D Hormone for Prostate Cancer

DTIC Science & Technology

2006-10-01

Acetic Anhydride / Pyridine/ 40C 1. UV / Toluene 2. EtOH - Reflux TBDMSCl / Imidazole /DMF BrCH2COOH / DCC / DMAP / CH2Cl2 1,25(OH)2D3-3-BE Figure 1...BE OH SO2 OTBDMS OH OTBDMS 1. Liq. SO2 / Reflux 2. TBDMSCl / Imidazole /DMF NaHCO3 / EtOH / Reflux NMO / SeO2 / CH2Cl2 / Reflux OH OTBDMSHO OTHP...containing 200 mg of 25-hydroxyvitamin D3 in a flask fitted with a trap that was cooled with dry ice-acetone (-780C). The yellow solution was refluxed

76 FR 3678 - Board Meeting: February 16, 2011-Las Vegas, NV, the U.S. Nuclear Waste Technical Review Board...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-20

... NUCLEAR WASTE TECHNICAL REVIEW BOARD Board Meeting: February 16, 2011--Las Vegas, NV, the U.S. Nuclear Waste Technical Review Board Will Meet To Discuss DOE Activities Related to Managing Spent Nuclear...-203, Nuclear Waste Policy Amendments Act of 1987, the U.S. Nuclear Waste Technical Review Board will...

76 FR 24065 - Board Workshop: June 6-7, 2011-Arlington, Virginia; the U.S. Nuclear Waste Technical Review Board...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-29

... NUCLEAR WASTE TECHNICAL REVIEW BOARD Board Workshop: June 6-7, 2011--Arlington, Virginia; the U.S. Nuclear Waste Technical Review Board Will Hold a Workshop on Methods for Evaluating Nuclear Waste Streams... 1987, the U.S. Nuclear Waste Technical Review Board will hold a workshop on Monday, June 6, and Tuesday...

Technical Features of Curriculum-Based Measurement in Writing: A Literature Review

ERIC Educational Resources Information Center

McMaster, Kristen; Espin, Christine

2007-01-01

This article reviews research examining technical features of curriculum-based measurement (CBM) in written expression. Twenty-eight technical reports and published articles are included in this review. Studies examining the development and technical adequacy of measures of written expression are summarized, beginning with research conducted at…

The synthesis, structure and properties of N-acetylated derivatives of ethyl 3-amino-1H-pyrazole-4-carboxylate.

PubMed

Kusakiewicz-Dawid, Anna; Masiukiewicz, Elzbieta; Rzeszotarska, Barbara; Dybała, Izabela; Kozioł, Anna Eugenia; Broda, Małgorzata Anna

2007-05-01

Ethyl 3-amino-1H-pyrazole-4-carboxylate (1) was yielded through total synthesis and reacted with acetic anhydride to give the acetylated products 2-6. Compounds 1-6 were studied with HPLC, X-ray, FT-IR, (1)H-NMR, (13)C-NMR and MS. Acetylation was carried out in solvents of various polarity, namely; chloroform; dioxane; DMF; acetic anhydride, at room temperature and at boiling points; and in the presence and absence of DMAP. The acetylated products are mainly nitrogen atoms in the ring. The position of the ring proton in the solution was based on NOESY; multinuclear HMBC, HSQC spectra and calculations. For equivalent amounts (1-1.5 mol) of acetic anhydride at room temperature two products of monoacetylation are produced in the ring: 2 and 3, ca. 2 : 1 and at the same time only small amount of the third product of monoacetylated, 5 in DMF, as well the product diacetylated, 4. The greatest amount of the product 4 is produced during the reaction with chloroform. However, in this solvent and in dioxane no product 5 is produced. Compound 2 is, largely, formed in dimethylformamide, in the presence DMAP, 0.2 eq. In the presence of this catalytic base, for the first hour, there is a mixture 2 and 3 to the ratio ca. 95 : 5. With 8 eq of Ac(2)O at reflux, after another hour, the compounds 3, 4 and 6 appear about equal amounts. After a longer time, the compound, which appears most in this mixture is triacetylated derivative 6. The structural and spectroscopic characteristics of compounds 1-6 have been given and the methods for their preparation have been provided.

Generalized seismic analysis

NASA Technical Reports Server (NTRS)

Butler, Thomas G.

1993-01-01

There is a constant need to be able to solve for enforced motion of structures. Spacecraft need to be qualified for acceleration inputs. Truck cargoes need to be safeguarded from road mishaps. Office buildings need to withstand earthquake shocks. Marine machinery needs to be able to withstand hull shocks. All of these kinds of enforced motions are being grouped together under the heading of seismic inputs. Attempts have been made to cope with this problem over the years and they usually have ended up with some limiting or compromise conditions. The crudest approach was to limit the problem to acceleration occurring only at a base of a structure, constrained to be rigid. The analyst would assign arbitrarily outsized masses to base points. He would then calculate the magnitude of force to apply to the base mass (or masses) in order to produce the specified acceleration. He would of necessity have to sacrifice the determination of stresses in the vicinity of the base, because of the artificial nature of the input forces. The author followed the lead of John M. Biggs by using relative coordinates for a rigid base in a 1975 paper, and again in a 1981 paper . This method of relative coordinates was extended and made operational as DMAP ALTER packets to rigid formats 9, 10, 11, and 12 under contract N60921-82-C-0128. This method was presented at the twelfth NASTRAN Colloquium. Another analyst in the field developed a method that computed the forces from enforced motion then applied them as a forcing to the remaining unknowns after the knowns were partitioned off. The method was translated into DMAP ALTER's but was never made operational. All of this activity jelled into the current effort. Much thought was invested in working out ways to unshakle the analysis of enforced motions from the limitations that persisted.

Generalized seismic analysis

NASA Astrophysics Data System (ADS)

Butler, Thomas G.

1993-09-01

There is a constant need to be able to solve for enforced motion of structures. Spacecraft need to be qualified for acceleration inputs. Truck cargoes need to be safeguarded from road mishaps. Office buildings need to withstand earthquake shocks. Marine machinery needs to be able to withstand hull shocks. All of these kinds of enforced motions are being grouped together under the heading of seismic inputs. Attempts have been made to cope with this problem over the years and they usually have ended up with some limiting or compromise conditions. The crudest approach was to limit the problem to acceleration occurring only at a base of a structure, constrained to be rigid. The analyst would assign arbitrarily outsized masses to base points. He would then calculate the magnitude of force to apply to the base mass (or masses) in order to produce the specified acceleration. He would of necessity have to sacrifice the determination of stresses in the vicinity of the base, because of the artificial nature of the input forces. The author followed the lead of John M. Biggs by using relative coordinates for a rigid base in a 1975 paper, and again in a 1981 paper . This method of relative coordinates was extended and made operational as DMAP ALTER packets to rigid formats 9, 10, 11, and 12 under contract N60921-82-C-0128. This method was presented at the twelfth NASTRAN Colloquium. Another analyst in the field developed a method that computed the forces from enforced motion then applied them as a forcing to the remaining unknowns after the knowns were partitioned off. The method was translated into DMAP ALTER's but was never made operational. All of this activity jelled into the current effort. Much thought was invested in working out ways to unshakle the analysis of enforced motions from the limitations that persisted.

Electrophysiological, haemodynamic, and mitochondrial alterations induced by levobupivacaine during myocardial ischemia in a pig model: protection by lipid emulsions?

PubMed

Mamou, Zahida; Descotes, Jacques; Chevalier, Philippe; Bui-Xuan, Bernard; Romestaing, Caroline; Timour, Quadiri

2015-10-01

Accidental intravascular or high-dose injection of local anesthetics (LA) can result in serious, potentially life-threatening complications. Indeed, adequate supportive measures and the administration of lipid emulsions are required in such complications. The study's objectives were threefold: (i) evaluate the myocardial toxicity of levobupivacaine when administered intravenously; (ii) investigate levobupivacaine toxicity on cardiomyocytes mitochondrial functions and cellular structure; (iii) assess the protective effects of a lipid emulsion in the presence or absence of myocardial ischemia. Domestic pigs randomized into two groups of 24 animals each, with either preserved coronary circulation or experimental myocardial ischemia. Six animals from each group received either: (i) single IV injection of saline, (ii) lipid emulsion (Intralipid(®) ), (iii) levobupivacaine, (iv) combination levobupivacaine-Intralipid(®) . Serially measured endpoints included: heart rate, duration of the monophasic action potentials (dMAP), mean arterial pressure, and peak of the time derivative of left ventricular pressure (LV dP/dtmax ). In addition, the following cardiomyocytes mitochondrial functions were measured: reactive oxygen species (ROS) production, oxidative phosphorylation, and calcium retention capacity (CRC) as well as the consequences of ROS production on lipids, proteins, and DNA. IV injection of levobupivacaine induced sinus bradycardia and reduced dMAP and LV dP/dtmax . At the mitochondrial level, oxygen consumption and CRC were decreased. In contrast, ROS production was increased leading to enhanced lipid peroxidation and structural alterations of proteins and DNA. Myocardial ischemia was associated with global worsening of all changes. Intralipid(®) quickly improved haemodynamics. However, beneficial effects of Intralipid(®) were less clear after myocardial ischemia. © 2015 Société Française de Pharmacologie et de Thérapeutique.

MAP Reconstruction for Fourier Rebinned TOF-PET Data

PubMed Central

Bai, Bing; Lin, Yanguang; Zhu, Wentao; Ren, Ran; Li, Quanzheng; Dahlbom, Magnus; DiFilippo, Frank; Leahy, Richard M.

2014-01-01

Time-of-flight (TOF) information improves signal to noise ratio in Positron Emission Tomography (PET). Computation cost in processing TOF-PET sinograms is substantially higher than for nonTOF data because the data in each line of response is divided among multiple time of flight bins. This additional cost has motivated research into methods for rebinning TOF data into lower dimensional representations that exploit redundancies inherent in TOF data. We have previously developed approximate Fourier methods that rebin TOF data into either 3D nonTOF or 2D nonTOF formats. We refer to these methods respectively as FORET-3D and FORET-2D. Here we describe maximum a posteriori (MAP) estimators for use with FORET rebinned data. We first derive approximate expressions for the variance of the rebinned data. We then use these results to rescale the data so that the variance and mean are approximately equal allowing us to use the Poisson likelihood model for MAP reconstruction. MAP reconstruction from these rebinned data uses a system matrix in which the detector response model accounts for the effects of rebinning. Using these methods we compare performance of FORET-2D and 3D with TOF and nonTOF reconstructions using phantom and clinical data. Our phantom results show a small loss in contrast recovery at matched noise levels using FORET compared to reconstruction from the original TOF data. Clinical examples show FORET images that are qualitatively similar to those obtained from the original TOF-PET data but a small increase in variance at matched resolution. Reconstruction time is reduced by a factor of 5 and 30 using FORET3D+MAP and FORET2D+MAP respectively compared to 3D TOF MAP, which makes these methods attractive for clinical applications. PMID:24504374

MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome

PubMed Central

Wang, Kunning; Liang, Qiaoyi; Li, Xiaoxing; Tsoi, Ho; Zhang, Jingwan; Wang, Hua; Go, Minnie Y Y; Chiu, Philip W Y; Ng, Enders K W; Sung, Joseph J Y; Yu, Jun

2016-01-01

Background Using the promoter methylation assay, we have shown that MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2) is preferentially methylated in gastric cancer. We analysed its biological effects and prognostic significance in gastric cancer. Methods MDGA2 methylation status was evaluated by combined bisulfite restriction analysis and bisulfite genomic sequencing. The effects of MDGA2 re-expression or knockdown on cell proliferation, apoptosis and the cell cycle were determined. MDGA2 interacting protein was identified by mass spectrometry and MDGA2-related cancer pathways by reporter activity and PCR array analyses. The clinical impact of MDGA2 was assessed in 218 patients with gastric cancer. Results MDGA2 was commonly silenced in gastric cancer cells (10/11) and primary gastric cancers due to promoter hypermethylation. MDGA2 significantly inhibited cell proliferation by causing G1–S cell cycle arrest and inducing cell apoptosis in vitro, and suppressed xenograft tumour growth in both subcutaneous and orthotopic xenograft mouse models (both p<0.001). The anti-tumorigenic effect of MDGA2 was mediated through direct stabilising of DNA methyltransferase 1 associated protein 1 (DMAP1), which played a tumour suppressive role in gastric cancer. This interaction activated their downstream key elements of p53/p21 signalling cascades. Moreover, promoter methylation of MDGA2 was detected in 62.4% (136/218) of gastric cancers. Multivariate analysis showed that patients with MDGA2 hypermethylation had a significantly decreased survival (p=0.005). Kaplan–Meier survival curves showed that MDGA2 hypermethylation was significantly associated with shortened survival in patients with early gastric cancer. Conclusions MDGA2 is a critical tumour suppressor in gastric carcinogenesis; its hypermethylation is an independent prognostic factor in patients with gastric cancer. PMID:26206665

76 FR 47613 - Board Meeting: September 13-14, 2011-Salt Lake City, UT; the U.S. Nuclear Waste Technical Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-05

... NUCLEAR WASTE TECHNICAL REVIEW BOARD Board Meeting: September 13-14, 2011--Salt Lake City, UT; the U.S. Nuclear Waste Technical Review Board Will Meet To Discuss DOE Plans for Used Fuel Disposition R... Amendments Act of 1987, the U.S. Nuclear Waste Technical Review Board will hold a public meeting in Salt Lake...

24 CFR 902.68 - Technical review of results of PHAS physical condition indicator.

Code of Federal Regulations, 2012 CFR

2012-04-01

... physical condition indicator. 902.68 Section 902.68 Housing and Urban Development REGULATIONS RELATING TO... review of results of PHAS physical condition indicator. (a) Request for technical reviews. This section describes the process for requesting and granting technical reviews of physical inspection results. (1) For...

24 CFR 902.68 - Technical review of results of PHAS physical condition indicator.

Code of Federal Regulations, 2014 CFR

2014-04-01

... physical condition indicator. 902.68 Section 902.68 Housing and Urban Development REGULATIONS RELATING TO... review of results of PHAS physical condition indicator. (a) Request for technical reviews. This section describes the process for requesting and granting technical reviews of physical inspection results. (1) For...

24 CFR 902.68 - Technical review of results of PHAS physical condition indicator.

Code of Federal Regulations, 2013 CFR

2013-04-01

... physical condition indicator. 902.68 Section 902.68 Housing and Urban Development REGULATIONS RELATING TO... review of results of PHAS physical condition indicator. (a) Request for technical reviews. This section describes the process for requesting and granting technical reviews of physical inspection results. (1) For...

30 CFR 750.25 - Permit fees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... review fee with the permit application. (2) Technical review. Following receipt from OSM of a notice of administrative completeness, an applicant who pays by stage of review shall submit the technical review basic fee... area. (3) Permit issuance. Following receipt from OSM of a notice of technical adequacy, an applicant...

Technical Review Board Chairperson Guidelines for Conducting Technical Review Boards for Rocket Testing

DTIC Science & Technology

2011-08-17

to create a guide for technical review board chairperson conducting technical review boards for rocket testing performed by the Air Force Research ...BOARDS FOR ROCKET TESTING   TABLE OF CONTENTS List of Acronyms 1 Abstract 2 Chapter 1. Introduction 3 Introduction and Research Question 3...boards for rocket testing performed by the Air Force Research Laboratory’s Space Missile Propulsion Division located at Edwards Air Force Base in

Site Guidelines for a "Making Middle Grades Work" Technical Review Visit

ERIC Educational Resources Information Center

Southern Regional Education Board, 2004

2004-01-01

The purpose of the Technical Review Visit (TRV) is to follow up on the actions taken to implement the recommendations indicated for each challenge in the most recent Technical Assistance Visit (TAV) report. This document provides the following: (1) Site Guidelines for the Making Middle Grades Work (MMGW) Technical Review Visit; (2) Site Checklist;…

Design and quality standards for custom hybrid microcircuits

NASA Technical Reports Server (NTRS)

Allen, R. V.

1977-01-01

A hybrid microcircuit standard was developed after a thorough review of applicable NASA, military, industry, and technical society specifications and standards and compilation of comments from technical reviewers throughout the hybrid industry. The draft of the standard submitted to the technical reviewers, the comments from the reviewers, and the completed standard are discussed.

30 CFR 736.25 - Permit fees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... application. (2) Technical review. Following receipt from OSM of a notice of administrative completeness, an applicant who pays by stage of review shall submit the technical review basic fee, plus the per-acre fee for.... Following receipt from OSM of a notice of technical adequacy, an applicant who pays by stage of review shall...

24 CFR 902.68 - Technical review of results of PHAS physical condition indicator.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Technical review of results of PHAS physical condition indicator. 902.68 Section 902.68 Housing and Urban Development REGULATIONS RELATING TO... review of results of PHAS physical condition indicator. (a) Request for technical reviews. This section...

Geotechnical support and topical studies for nuclear waste geologic repositories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-01-01

The present report lists the technical reviews and comments made during the fiscal year 1988 and summarizes the technical progress of the topical studies. In the area of technical assistance, there were numerous activities detailed in the next section. These included 24 geotechnical support activities, including reviews of 6 Study Plans (SP) and participation in 6 SP Review Workshops, review of one whole document Site Characterization Plan (SCP) and participation in the Assembled Document SCP Review Workshops by 6 LBL reviewers; the hosting of a DOE program review, the rewriting of the project statement of work, 2 trips to technicalmore » and planning meetings; preparation of proposed work statements for two new topics for DOE, and 5 instances of technical assistance to DOE. These activities are described in a Table in the following section entitled Geoscience Technical Support for Nuclear Waste Geologic Repositories.''« less

75 FR 28857 - Agency Information Collection (Technical Industry Standards) Activities Under OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-24

... (Technical Industry Standards) Activities Under OMB Review AGENCY: Office of Acquisition and Logistics... Industry Standards. OMB Control Number: 2900-0586. Type of Review: Extension of a currently approved collection. Abstract: VAAR provision 852.211-75, Technical Industry Standards, requires that items offered...

75 FR 16461 - Meeting of the Mobile Sources Technical Review Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-01

... ENVIRONMENTAL PROTECTION AGENCY Meeting of the Mobile Sources Technical Review Subcommittee AGENCY... Committee Act, Public Law 92- 463, notice is hereby given that the Mobile Sources Technical Review... site: http://www.epa.gov/air/caaac/mobile_sources.html . MSTRS listserver subscribers will receive...

77 FR 60430 - Meeting of the Mobile Sources Technical Review Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9736-3] Meeting of the Mobile Sources Technical Review... Advisory Committee Act, Public Law 92- 463, notice is hereby given that the Mobile Sources Technical Review... Advisory Committee. This is an open meeting. The meeting will include discussion of current topics and...

78 FR 42821 - Agency Information Collection (Technical Industry Standards) Activities Under OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-17

... (Technical Industry Standards) Activities Under OMB Review AGENCY: Office of Acquisition and Logistics... Affairs Acquisition Regulation (VAAR) Provision 852.211-72 (formerly 852.211-75), Technical Industry.... Abstract: VAAR provision 852.211-72, Technical Industry Standards, requires items offered for sale to VA...

The Independent Technical Analysis Process Final Report 2006-2007.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duberstein, Corey; Ham, Kenneth; Dauble, Dennis

2007-03-01

The Bonneville Power Administration (BPA) contracted with the Pacific Northwest National Laboratory (PNNL) to provide technical analytical support for system-wide fish passage information (BPA Project No. 2006-010-00). The goal of this project was to produce rigorous technical analysis products using independent analysts and anonymous peer reviewers. This project provided an independent technical source for non-routine fish passage analyses while allowing routine support functions to be performed by other well-qualified entities. The Independent Technical Analysis Process (ITAP) was created to provide non-routine analysis for fish and wildlife agencies and tribes in particular and the public in general on matters related tomore » juvenile and adult salmon and steelhead passage through the mainstem hydrosystem. The process was designed to maintain the independence of analysts and reviewers from parties requesting analyses, to avoid potential bias in technical products. The objectives identified for this project were to administer a rigorous, transparent process to deliver unbiased technical assistance necessary to coordinate recommendations for storage reservoir and river operations that avoid potential conflicts between anadromous and resident fish. Seven work elements, designated by numbered categories in the Pisces project tracking system, were created to define and accomplish project goals as follows: (1) 118 Coordination - Coordinate technical analysis and review process: (a) Retain expertise for analyst/reviewer roles. (b) Draft research directives. (c) Send directive to the analyst. (d) Coordinate two independent reviews of the draft report. (e) Ensure reviewer comments are addressed within the final report. (2) 162 Analyze/Interpret Data - Implement the independent aspects of the project. (3) 122 Provide Technical Review - Implement the review process for the analysts. (4) 132 Produce Annual Report - FY06 annual progress report with Pisces Disseminate (5) 161 Disseminate Raw/Summary Data and Results - Post technical products on the ITAP web site. (6) 185-Produce Pisces Status Report - Provide periodic status reports to BPA. (7) 119 Manage and Administer Projects - project/contract administration.« less

78 FR 63251 - Board Meeting; November 20, 2013 in Washington, DC

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-23

... NUCLEAR WASTE TECHNICAL REVIEW BOARD Board Meeting; November 20, 2013 in Washington, DC The U.S. Nuclear Waste Technical Review Board will meet to discuss DOE SNF and HLW management research and... Policy Amendments Act of 1987, the U.S. Nuclear Waste Technical Review Board will hold a public meeting...

76 FR 77270 - Board Meeting; January 9, 2012, Arlington, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

... NUCLEAR WASTE TECHNICAL REVIEW BOARD Board Meeting; January 9, 2012, Arlington, VA The U.S. Nuclear Waste Technical Review Board will meet to discuss integration efforts undertaken by DOE-NE and DOE... Amendments Act of 1987, the U.S. Nuclear Waste Technical Review Board will hold a public meeting in Arlington...

75 FR 73085 - National Toxicology Program (NTP): Office of Liaison, Policy, and Review; Availability of Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

..., Policy, and Review; Availability of Draft NTP Technical Reports; Request for Comments; Announcement of a Panel Meeting to Peer Review Draft NTP Technical Reports AGENCY: National Institute of Environmental... NTP Technical Reports (TRs; available at http://ntp.niehs.nih.gov/go/36051 ) that will be peer...

76 FR 8741 - National Toxicology Program (NTP): Office of Liaison, Policy, and Review; Availability of Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-15

..., Policy, and Review; Availability of Draft NTP Technical Reports; Request for Comments; Announcement of a Panel Meeting To Peer Review Draft NTP Technical Reports AGENCY: National Institute of Environmental... NTP Technical Reports (TRs; available at http://ntp.niehs.nih.gov/go/36051 ) that will be peer...

Novel Hybrid Molecules on the Basis of Steroids and (5Z,9Z)-Tetradeca-5,9-dienoic Acid: Synthesis, Anti-Cancer Studies and Human Topoisomerase I Inhibitory Activity.

PubMed

D'yakonov, Vladimir A; Dzhemileva, Lilya U; Tuktarova, Regina A; Ishmukhametova, Svetlana R; Yunusbaeva, Milyausha M; Ramazanova, Ilfir R; Dzhemilev, Usein M

2017-01-01

Novel steroid derivatives of 5Z,9Z-dienoic acids were prepared by the DCC/DMAP-catalyzed esterification of (5Z,9Z)-tetradeca-5,9-dienoic acid with hydroxy steroids. High cytotoxicity towards the HEK293, Jurkat, K562 cancer cell lines and human topoisomerase I (hTop1) inhibitory activity in vitro were found for the synthesized acids. A probable mechanism of topoisomerase I inhibition was hypothesized on the basis of in silico studies resorting to docking. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Nonlinear random response prediction using MSC/NASTRAN

NASA Technical Reports Server (NTRS)

Robinson, J. H.; Chiang, C. K.; Rizzi, S. A.

1993-01-01

An equivalent linearization technique was incorporated into MSC/NASTRAN to predict the nonlinear random response of structures by means of Direct Matrix Abstract Programming (DMAP) modifications and inclusion of the nonlinear differential stiffness module inside the iteration loop. An iterative process was used to determine the rms displacements. Numerical results obtained for validation on simple plates and beams are in good agreement with existing solutions in both the linear and linearized regions. The versatility of the implementation will enable the analyst to determine the nonlinear random responses for complex structures under combined loads. The thermo-acoustic response of a hexagonal thermal protection system panel is used to highlight some of the features of the program.

Numerical solution of Euler's equation by perturbed functionals

NASA Technical Reports Server (NTRS)

Dey, S. K.

1985-01-01

A perturbed functional iteration has been developed to solve nonlinear systems. It adds at each iteration level, unique perturbation parameters to nonlinear Gauss-Seidel iterates which enhances its convergence properties. As convergence is approached these parameters are damped out. Local linearization along the diagonal has been used to compute these parameters. The method requires no computation of Jacobian or factorization of matrices. Analysis of convergence depends on properties of certain contraction-type mappings, known as D-mappings. In this article, application of this method to solve an implicit finite difference approximation of Euler's equation is studied. Some representative results for the well known shock tube problem and compressible flows in a nozzle are given.

NESC Independent Review of the Mars Reconnaissance Orbiter (MRO) Contamination Thermal/Vacuum (T/V) Anomaly Technical Consultation Report

NASA Technical Reports Server (NTRS)

Sutter, James K.; Leidecker, Henning W.; Panda, Binayak; Piascik, Robert S.; Muirhead, Brian K.; Peeler, Debra

2009-01-01

The NESC eras requested by the NASA Jet Propulsion Laboratory (JPL) to conduct an independent review of the Mars Reconnaissance Orbiter (MRO) Thermal/Vacuum (T/V) Anomaly Assessment. Because the anomaly resulted in the surface contamination of the MRO, selected members of the Materials Super Problem Resolution Team (SPRT) and the NASA technical community having technical expertise relative to contamination issues were chosen for the independent review. The consultation consisted of a review of the MRO Project's reported response to the assessment findings, a detailed review of JPL technical assessment final report, and detailed discussions with the JPL assessment team relative to their findings.

Spatial abilities and technical skills performance in health care: a systematic review.

PubMed

Langlois, Jean; Bellemare, Christian; Toulouse, Josée; Wells, George A

2015-11-01

The aim of this study was to conduct a systematic review and meta-analysis of the relationship between spatial abilities and technical skills performance in health care in beginners and to compare this relationship with those in intermediate and autonomous learners. Search criteria included 'spatial abilities' and 'technical skills'. Keywords related to these criteria were defined. A literature search was conducted to 20 December, 2013 in Scopus (including MEDLINE) and in several databases on EBSCOhost platforms (CINAHL Plus with Full Text, ERIC, Education Source and PsycINFO). Citations were obtained and reviewed by two independent reviewers. Articles related to retained citations were reviewed and a final list of eligible articles was determined. Articles were assessed for quality using the Scottish Intercollegiate Guidelines Network-50 assessment instrument. Data were extracted from articles in a systematic way. Correlations between spatial abilities test scores and technical skills performance were identified. A series of 8289 citations was obtained. Eighty articles were retained and fully reviewed, yielding 36 eligible articles. The systematic review found a tendency for spatial abilities to be negatively correlated with the duration of technical skills and positively correlated with the quality of technical skills performance in beginners and intermediate learners. Pooled correlations of studies were -0.46 (p = 0.03) and -0.38 (95% confidence interval [CI] -0.53 to -0.21) for duration and 0.33 (95% CI 0.20-0.44) and 0.41 (95% CI 0.26-0.54) for quality of technical skills performance in beginners and intermediate learners, respectively. However, correlations between spatial abilities test scores and technical skills performance were not statistically significant in autonomous learners. Spatial abilities are an important factor to consider in selecting and training individuals in technical skills in health care. © 2015 John Wiley & Sons Ltd.

Ground Water Technical Considerations during the Five-Year Review Process

EPA Pesticide Factsheets

This issue paper has been developed to highlight technical considerations as well as technical resources available to Remedial Project Managers (RPMs) in conducting Five-Year Reviews (FYRs) at CERCLA1 sites with contaminated groundwater.

Technical Packages in Injury and Violence Prevention to Move Evidence into Practice: Systematic Reviews and Beyond

PubMed Central

Haegerich, Tamara M.; David-Ferdon, Corinne; Noonan, Rita K.; Manns, Brian J.; Billie, Holly C.

2016-01-01

Injury and violence prevention strategies have greater potential for impact when they are based on scientific evidence. Systematic reviews of the scientific evidence can contribute key information about which policies and programs might have the greatest impact when implemented. However, systematic reviews have limitations, such as lack of implementation guidance and contextual information, that can limit the application of knowledge. “Technical packages,” developed by knowledge brokers such as the federal government, nonprofit agencies, and academic institutions, have the potential to be an efficient mechanism for making information from systematic reviews actionable. Technical packages provide information about specific evidence-based prevention strategies, along with the estimated costs and impacts, and include accompanying implementation and evaluation guidance to facilitate adoption, implementation, and performance measurement. We describe how systematic reviews can inform the development of technical packages for practitioners, provide examples of technical packages in injury and violence prevention, and explain how enhancing review methods and reporting could facilitate the use and applicability of scientific evidence. PMID:27604301

[Endovascular radiofrequency denervation of renal arteries as an innovation method of treatment of refractory arterial hypertension. First experience in Russia].

PubMed

Danilov, N M; Matchin, Iu G; Chazova, I E

2012-01-01

Excessive activation of the sympathetic nervous system forms the basis of pathogenesis of essential arterial hypertension (AH). The present work was aimed at evaluating efficacy and safety of endovascular radiofrequency denervation of renal arteries in patients with AH refractory AH based on the initial first experience in with using this methodology in the Russian Federation. The interventions were carried out on December 14-15th, 2011 in the first five patients presenting with AH refractory to antihypertensive therapy consisting of three and more drugs in therapeutic doses, one of which was a diuretic. The selection criteria were systolic arterial pressure (SAP) ≥160 mm Hg or ≥150 mm Hg in the presence of type 2 diabetes mellitus. The obligatory conditions for selection were the preserved renal function [glomerular filtration rate (GFR) ≥45 ml/min] and the absence of the secondary form of AH. The procedure of denervation was performed in the conditions of roentgen-operating room using special Medtronic Ardian Simplicity Catheter System™. In all cases we managed to perform bilateral denervation of renal arteries with the radiofrequency effect in not less than 4 zones of each of vessels. Efficacy of each of the effect was registered with due regard for reaching certain temperature and values of impedance. The interventions were not accompanied by the development of any complications either in the area of manipulations or the site of puncture. Neither were there any complications from the side of the cardiovascular or excretory systems of the body. Diurnal monitoring of AP (DMAP) registered a significant decrease in SAP averagely from 174±12 to 145±10 mm Hg three days after the intervention. A persistent antihypertensive effect was confirmed by the DMAP findings one month after denervation - the SAP level averagely amounted to 131±6 mm Hg. Endovascular radiofrequency denervation of renal arteries is a safe and efficient method of treatment of AH resistant to multicomponent antihypertensive therapy.

Azapsoralens: new potential photochemotherapeutic agents for psoriasis.

PubMed

Vedaldi, D; Caffieri, S; Miolo, G; Dall'Acqua, F; Baccichetti, F; Guiotto, A; Benetollo, F; Bombieri, G; Recchia, G; Cristofolini, M

1991-12-01

New bioisoters of psoralen, obtained by replacing carbon 8 of the central benzene ring with a nitrogen, were studied from the photochemical, photobiological and phototherapeutic points of view. In particular, 4,4'-, 4',5'-dimetyl, 4,4',5'-trimethyl and 3,4,4',5'-tetramethylazapsoralen were studied. The crystal and molecular structure of 4,4',5'-trimethylazapsoralen, obtained by X ray diffraction, was also reported. Like psoralen, these compounds form a molecular complex with DNA, undergoing intercalation inside the double helix of the macromolecule. When irridiated with long ultraviolet light (365 nm), the intercalated drug photoconjugates covalently to the macromolecule, forming mono- and diadducts. The photobinding rate show the following order of magnitude: 4,4',5'-trimetylazapsoralen (4,4',5'-TMAP) = 3,4,4',5'-tetramethylazapsoralen (3,4,4',5'-TMAP) greater than 4',5'-dimethylazapsoralen (4',5'-DMAP) = 4,4'-dimethylazapsoralen (4,4'-DMAP). The DNA photobinding rate of 8-methoxypsoralen (8-MOP), taken as reference compound, is similar to that of the two dimetylazapsoralens but lower than tri- and tetramethyl derivatives. The ability of azapsoralens to form cross-links in DNA is lower than that of 8-MOP. However, capacity to induce cross-links does not parallel the DNA photobinding rate; it is higher for trimethyl derivate and lower for tetramethylazapsoralen. Azapsoralens show evident antiproliferative activity. The trimethyl derivative is the most active, followed by tetrametyl, both these compounds showing activity slightly higher than that of 8-MOP. The two dimethylderivatives are less active. The mautagenic activity of azapsoralens on E. coli WP2 TM6 is lower than that of 8-MOP in the same conditions. The new compounds do not show any skin phototoxicity on guinea pig skin. On the basis of its DNA photobinding, antiproliferative activity, mutagenicity and lack of skin phototoxicity, 4,4',5'-TMAP was chosen for clinical evaluation. Clinical results obtained by topical treatment of psoriatic plaques reveal evident therapeutic effectiveness and clearing is between good and moderate, although 8-MOP, used as reference compound, is more effective.

MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome.

PubMed

Wang, Kunning; Liang, Qiaoyi; Li, Xiaoxing; Tsoi, Ho; Zhang, Jingwan; Wang, Hua; Go, Minnie Y Y; Chiu, Philip W Y; Ng, Enders K W; Sung, Joseph J Y; Yu, Jun

2016-10-01

Using the promoter methylation assay, we have shown that MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2) is preferentially methylated in gastric cancer. We analysed its biological effects and prognostic significance in gastric cancer. MDGA2 methylation status was evaluated by combined bisulfite restriction analysis and bisulfite genomic sequencing. The effects of MDGA2 re-expression or knockdown on cell proliferation, apoptosis and the cell cycle were determined. MDGA2 interacting protein was identified by mass spectrometry and MDGA2-related cancer pathways by reporter activity and PCR array analyses. The clinical impact of MDGA2 was assessed in 218 patients with gastric cancer. MDGA2 was commonly silenced in gastric cancer cells (10/11) and primary gastric cancers due to promoter hypermethylation. MDGA2 significantly inhibited cell proliferation by causing G1-S cell cycle arrest and inducing cell apoptosis in vitro, and suppressed xenograft tumour growth in both subcutaneous and orthotopic xenograft mouse models (both p<0.001). The anti-tumorigenic effect of MDGA2 was mediated through direct stabilising of DNA methyltransferase 1 associated protein 1 (DMAP1), which played a tumour suppressive role in gastric cancer. This interaction activated their downstream key elements of p53/p21 signalling cascades. Moreover, promoter methylation of MDGA2 was detected in 62.4% (136/218) of gastric cancers. Multivariate analysis showed that patients with MDGA2 hypermethylation had a significantly decreased survival (p=0.005). Kaplan-Meier survival curves showed that MDGA2 hypermethylation was significantly associated with shortened survival in patients with early gastric cancer. MDGA2 is a critical tumour suppressor in gastric carcinogenesis; its hypermethylation is an independent prognostic factor in patients with gastric cancer. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

48 CFR 1348.102 - Policies.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-submitted Value Engineering Change Proposals (VECPs) to the appropriate technical personnel for review. (b) Technical personnel shall conduct a comprehensive review of VECPs for technical feasibility, usefulness, and adequacy of the contractor's estimate of cost savings; make a written report; and recommend acceptance or...

Astrobee Periodic Technical Review (PTR) Delta 3

NASA Technical Reports Server (NTRS)

Provencher, Christopher; Smith, Marion F.; Smith, Ernest Everett; Bualat, Maria Gabriele; Barlow, Jonathan Spencer

2017-01-01

Astrobee is a free flying robot for the inside of the International Space Station (ISS). The Periodic Technical Review (PTR) delta 3 is the final design review of the system presented to stakeholders.

SU-E-CAMPUS-J-04: Image Guided Radiation Therapy (IGRT): Review of Technical Standards and Credentialing in Radiotherapy Clinical Trials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giaddui, T; Chen, W; Yu, J

2014-06-15

Purpose: To review IGRT credentialing experience and unexpected technical issues encountered in connection with advanced radiotherapy technologies as implemented in RTOG clinical trials. To update IGRT credentialing procedures with the aim of improving the quality of the process, and to increase the proportion of IGRT credentialing compliance. To develop a living disease site-specific IGRT encyclopedia. Methods: Numerous technical issues were encountered during the IGRT credentialing process. The criteria used for credentialing review were based on: image quality; anatomy included in fused data sets and shift results. Credentialing requirements have been updated according to the AAPM task group reports for IGRTmore » to ensure that all required technical items are included in the quality review process. Implementation instructions have been updated and expanded for recent protocols. Results: Technical issues observed during the credentialing review process include, but are not limited to: poor quality images; inadequate image acquisition region; poor data quality; shifts larger than acceptable; no soft tissue surrogate. The updated IGRT credentialing process will address these issues and will also include the technical items required from AAPM: TG 104; TG 142 and TG 179 reports. An instruction manual has been developed describing a remote credentialing method for reviewers. Submission requirements are updated, including images/documents as well as facility questionnaire. The review report now includes summary of the review process and the parameters that reviewers check. We have reached consensus on the minimum IGRT technical requirement for a number of disease sites. RTOG 1311(NRG-BR002A Phase 1 Study of Stereotactic Body Radiotherapy (SBRT) for the Treatment of Multiple Metastases) is an example, here; the protocol specified the minimum requirement for each anatomical sites (with/without fiducials). Conclusion: Technical issues are identified and reported. IGRT guidelines are updated, with the corresponding credentialing requirements. An IGRT encyclopedia describing site-specific implementation issues is currently in development.« less

Interaction of the HIV NCp7 Protein with Platinum(II) and Gold(III) Complexes Containing Tridentate Ligands.

PubMed

Bernardes, Victor H F; Qu, Yun; Du, Zhifeng; Beaton, James; Vargas, Maria D; Farrell, Nicholas P

2016-11-07

The human immunodeficiency virus (HIV) nucleocapsid protein (NCp7) plays significant roles in the virus life cycle and has been targeted by compounds that could lead to its denaturation or block its interaction with viral RNA. Herein, we describe the interactions of platinum(II) and gold(III) complexes with NCp7 and how the reactivity/affinity of potential inhibitors can be modulated by judicious choice of ligands. The interactions of [MCl(N 3 )] n+ (M = Pt 2+ (n = 1) and Au 3+ (n = 2); N 3 = tridentate chelate ligands: bis(2-pyridylmethyl)methylamine (Mebpma, L 1 ) and bis(2-pyridylmethyl)amine (bpma, L 2 ) with the C-terminal zinc finger of NCp7 (ZF2) were investigated by electrospray ionization-mass spectroscopy (ESI-MS). Mass spectra from the incubation of [MCl(Mebpma)] n+ complexes (PtL 1 and AuL 1 ) with ZF2 indicated that they were more reactive than the previously studied diethylenetriamine-containing analogues [MCl(dien)] n+ . The initial product of reaction of PtL 1 with ZF2 results in loss of all ligands and release of zinc to give the platinated apopeptide {PtF} (F = apopeptide). This is in contrast to the incubation with [PtCl(dien)] + , in which {Pt(dien)}-peptide adducts are observed. Incubation of the Au 3+ complex AuL 1 with ZF2 gave Au x F n+ species (x = 1, 2, 4, F = apopeptide) again with loss of all ligands. Furthermore, the formally substitution-inert analogues [Pt(N 3 )L] 2+ (L = 4-methylpyridine (4-pic), 4-dimethylaminopyridine (dmap), and 9-ethylguanine (9-EtGua)) were prepared to examine stacking interactions with N-acetyltryptophan (N-AcTrp), the Trp-containing ZF2, and the "full" two-finger NCp7 itself using fluorescence quenching titration. Use of bpma and Mebpma gave slightly higher affinity than analogous [Pt(dien)L)] 2+ complexes. The dmap-containing complexes (PtL 1 a and PtL 2 a) had the greatest association constants (K a ) for N-AcTrp and ZF2 peptide. The complex PtL 1 a had the highest K a when compared with other known Pt 2+ analogues: [Pt(dien)(9-EtGua)] 2+ < [Pt(bpma)(9-EtGua)] 2+ < [Pt(dien)(dmap)] 2+ < PtL 2 a < PtL 1 a. A K a value of ca. 40.6 ± 1.0 × 10 3 M -1 was obtained for the full NCp7 peptide with PtL 1 a. In addition, the mass spectrum of the interaction between ZF2 and PtL 1 a confirms formation of a 1:1 PtL 1 a/ZF2 adduct. The reactivity of selected complexes with sulfur-containing amino acid N-acetylcysteine (N-AcCys) was also investigated by 195 Pt and 1 H NMR spectroscopy and ESI-MS. The precursor compounds [PtCl(N 3 )] + PtL 1 and PtL 2 reacted readily, whereas their [Pt(N 3 )L] 2+ analogues PtL 1 a and PtL 2 a were inert to substitution.

TADS Needs Assessment Procedures Manual, Summer 1980.

ERIC Educational Resources Information Center

Black, Talbot; And Others

The TADS (Technical Assistance Development System) Needs Assessment Manual is designed to guide the comprehensive review of Handicapped Children's Early Education Program (HCEEP) demonstration projects in identifying technical assistance needs. An introduction reviews the TADS technical assistance model which includes program planning, needs…

Technical Packages in Injury and Violence Prevention to Move Evidence Into Practice: Systematic Reviews and Beyond.

PubMed

Haegerich, Tamara M; David-Ferdon, Corinne; Noonan, Rita K; Manns, Brian J; Billie, Holly C

2016-09-07

Injury and violence prevention strategies have greater potential for impact when they are based on scientific evidence. Systematic reviews of the scientific evidence can contribute key information about which policies and programs might have the greatest impact when implemented. However, systematic reviews have limitations, such as lack of implementation guidance and contextual information, that can limit the application of knowledge. "Technical packages," developed by knowledge brokers such as the federal government, nonprofit agencies, and academic institutions, have the potential to be an efficient mechanism for making information from systematic reviews actionable. Technical packages provide information about specific evidence-based prevention strategies, along with the estimated costs and impacts, and include accompanying implementation and evaluation guidance to facilitate adoption, implementation, and performance measurement. We describe how systematic reviews can inform the development of technical packages for practitioners, provide examples of technical packages in injury and violence prevention, and explain how enhancing review methods and reporting could facilitate the use and applicability of scientific evidence. © The Author(s) 2016.

A Review and Evaluation of the Langley Research Center's Scientific and Technical Information Program. Results of Phase VI-The Technical Report: A Survey and Analysis.

ERIC Educational Resources Information Center

McCullough, Robert A.; And Others

This report presents the results of a review and evaluation of the Langley Research Center's scientific and technical information program, which examined technical reports from various institutions and organizations to determine the organization of reports, the language used to convey information, and the methods used to present information.…

Technical and Vocational Education in Asia and Oceania. Bulletin of the Unesco Regional Office for Education in Asia and Oceania. Number 21, June 1980.

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and Oceania.

This issue contains a regional review, discussion of technical and vocational education in countries of Asia and Oceania, articles dealing with various aspects of technical and vocational education, and a bibliographical supplement. The brief statistical review in section 1 concerns second-level technical and vocational education in the developing…

4-(Di­methyl­amino)­pyridinium trichlorido[4-(di­methyl­amino)­pyridine-κN]cobaltate(II)

PubMed Central

Guenifa, Fatiha; Hadjadj, Nasreddine; Zeghouan, Ouahida; Bendjeddou, Lamia; Merazig, Hocine

2013-01-01

In the anion of the title compound, (C7H11N2)[CoCl3(C7H10N2)], the CoII ion is coordinated by one N atom from a 4-(di­methyl­amino)­pyridine (DMAP) ligand and three Cl atoms, forming a CoNCl3 polyhedron with a distorted tetra­hedral geometry. In the crystal, cations and anions are linked via weak N—H⋯Cl and C—H⋯Cl hydrogen bonds. Double layers of complex anions stack along the b- axis direction, which alternate with double layers of 4-(di­methyl­amino)-pyridinium cations. PMID:24046560

A TEMPO-free copper-catalyzed aerobic oxidation of alcohols.

PubMed

Xu, Boran; Lumb, Jean-Philip; Arndtsen, Bruce A

2015-03-27

The copper-catalyzed aerobic oxidation of primary and secondary alcohols without an external N-oxide co-oxidant is described. The catalyst system is composed of a Cu/diamine complex inspired by the enzyme tyrosinase, along with dimethylaminopyridine (DMAP) or N-methylimidazole (NMI). The Cu catalyst system works without 2,2,6,6-tetramethyl-l-piperidinoxyl (TEMPO) at ambient pressure and temperature, and displays activity for un-activated secondary alcohols, which remain a challenging substrate for catalytic aerobic systems. Our work underscores the importance of finding alternative mechanistic pathways for alcohol oxidation, which complement Cu/TEMPO systems, and demonstrate, in this case, a preference for the oxidation of activated secondary over primary alcohols. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A reagent for safe and efficient diazo-transfer to primary amines: 2-azido-1,3-dimethylimidazolinium hexafluorophosphate.

PubMed

Kitamura, Mitsuru; Kato, So; Yano, Masakazu; Tashiro, Norifumi; Shiratake, Yuichiro; Sando, Mitsuyoshi; Okauchi, Tatsuo

2014-07-07

Organic azides were prepared from primary amines in high yields by a metal free diazo-transfer reaction using 2-azido-1,3-dimethylimidazolinium hexafluorophosphate (ADMP), which is safe and stable crystalline. The choice of base was important in the diazo-transfer reaction. In general, 4-(N,N-dimethyl)aminopyridine (DMAP) was efficient, but a stronger base such as alkylamine or DBU was more appropriate for the reaction of nucleophilic primary amines. X-ray single crystal structural analysis and geometry optimization using density functional theory (B3LYP/6-31G**) were conducted to study the ADMP structure, and the diazo-transfer reaction mechanism was explained with the help of the results of these analyses.

40 CFR 40.150 - Evaluation of applications.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... Relevancy, coupled with the results of technical review, will provide the basis for funding recommendations... will be reviewed for technical merit by at least one reviewer within EPA and at least two reviewers.... Recommendations for continuation of funding will be based on progress toward the accomplishment of the goals set...

14 CFR 1260.17 - Evaluation and selection of unsolicited proposals.

Code of Federal Regulations, 2010 CFR

2010-01-01

.... NASA recommends contact with NASA technical personnel before submission of an unsolicited proposal to...) prepared by the cognizant technical office. The JAUP shall be submitted for the approval of the grant officer after review and concurrence at a level above the technical officer. However, review and...

Trends in Career and Technical Education Research

ERIC Educational Resources Information Center

Rojewski, Jay W.; Asunda, Paul; Kim, Soo Jung

2008-01-01

The purpose of this literature review was to identify current trends and issues in research focusing on career and technical education (CTE). The primary sources of literature for this review included all research articles published in three refereed scholarly journals--"Career and Technical Education Research," "Journal of Career and Technical…

Non-technical skills of the operating theatre scrub nurse: literature review.

PubMed

Mitchell, Lucy; Flin, Rhona

2008-07-01

This paper is a report of a review to identify the non-technical (cognitive and social) skills used by scrub nurses. Recognition that failures in non-technical skills contributed to accidents in high-risk industries led to the development of research programmes to study the role of cognition and social interactions in operational safety. Recently, psychological research in operating theatres has revealed the importance of non-technical skills in safe and efficient performance. Most of the studies to date have focused on anaesthetists and surgeons. On-line sources and university library catalogues, publications of the Association for Perioperative Practice, National Association of Theatre Nurses and Association of Peri-Operative Registered Nurses were searched in 2007. Studies were included in the review if they presented data from scrub nurses on one or more of their non-technical skills. These findings were examined in relation to an existing medical non-technical skills framework with categories of communication, teamwork, leadership, situation awareness and decision-making. Of 424 publications retrieved, 13 were reviewed in detail. Ten concerned communication and eight of those also had data on teamwork. In 11 papers teamwork was examined, and one focused on nurses' situation awareness, teamwork and communication. None of the papers we reviewed examined leadership or decision-making by scrub nurses. Further work is needed to identify formally the non-technical skills which are important to the role of scrub nurse and then to design training in the identified non-technical skills during the education and development of scrub nurses.

44 CFR 70.4 - Review by the Administrator.

Code of Federal Regulations, 2010 CFR

2010-10-01

... MAP CORRECTION Mapping Deficiencies Unrelated to Community-Wide Elevation Determinations § 70.4 Review by the Administrator. The Administrator, after reviewing the scientific or technical information... within 60 days after we receive the applicant's scientific or technical information that we have compared...

44 CFR 70.4 - Review by the Administrator.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MAP CORRECTION Mapping Deficiencies Unrelated to Community-Wide Elevation Determinations § 70.4 Review by the Administrator. The Administrator, after reviewing the scientific or technical information... within 60 days after we receive the applicant's scientific or technical information that we have compared...

NUSC Technical Publications Guide.

DTIC Science & Technology

1985-05-01

Facility personnel especially that of A. Castelluzzo, E. Deland, J. Gesel , and E. Szlosek (all of Code 4343). Reviewed and Approved: 14 July 1980 D...their technical content and format. Review and approve the manual outline, the review manuscript, and the final camera - reproducible copy. Conduct in

Technical Change in the North American Forestry Sector: A Review

Treesearch

Jeffery C. Stier; David N. Bengston

1992-01-01

Economists have examined the impact of technical change on the forest products sector using the historical, index number, and econometric approaches. This paper reviews econometric analyses of the rate and bias of technical change, examining functional form, factors included, and empirical results. Studies are classified as first- second-, or third-generation...

48 CFR 801.602-82 - Documents to submit for legal or technical review-general.

Code of Federal Regulations, 2010 CFR

2010-10-01

... legal or technical review-general. 801.602-82 Section 801.602-82 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION REGULATION SYSTEM Career... review—general. Table 801.602-82 specifies the documents that must be submitted when a legal or technical...

Assessing Technical Competence in Surgical Trainees: A Systematic Review.

PubMed

Szasz, Peter; Louridas, Marisa; Harris, Kenneth A; Aggarwal, Rajesh; Grantcharov, Teodor P

2015-06-01

To systematically examine the literature describing the methods by which technical competence is assessed in surgical trainees. The last decade has witnessed an evolution away from time-based surgical education. In response, governing bodies worldwide have implemented competency-based education paradigms. The definition of competence, however, remains elusive, and the impact of these education initiatives in terms of assessment methods remains unclear. A systematic review examining the methods by which technical competence is assessed was conducted by searching MEDLINE, EMBASE, PsychINFO, and the Cochrane database of systematic reviews. Abstracts of retrieved studies were reviewed and those meeting inclusion criteria were selected for full review. Data were retrieved in a systematic manner, the validity and reliability of the assessment methods was evaluated, and quality was assessed using the Grading of Recommendations Assessment, Development and Evaluation classification. Of the 6814 studies identified, 85 studies involving 2369 surgical residents were included in this review. The methods used to assess technical competence were categorized into 5 groups; Likert scales (37), benchmarks (31), binary outcomes (11), novel tools (4), and surrogate outcomes (2). Their validity and reliability were mostly previously established. The overall Grading of Recommendations Assessment, Development and Evaluation for randomized controlled trials was high and low for the observational studies. The definition of technical competence continues to be debated within the medical literature. The methods used to evaluate technical competence predominantly include instruments that were originally created to assess technical skill. Very few studies identify standard setting approaches that differentiate competent versus noncompetent performers; subsequently, this has been identified as an area with great research potential.

Underground Test Area Activity Preemptive Review Guidance Nevada National Security Site, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farnham, Irene; Rehfeldt, Kenneth

Preemptive reviews (PERs) of Underground Test Area (UGTA) Activity corrective action unit (CAU) studies are an important and long-maintained quality improvement process. The CAU-specific PER committees provide internal technical review of ongoing work throughout the CAU lifecycle. The reviews, identified in the UGTA Quality Assurance Plan (QAP) (Sections 1.3.5.1 and 3.2), assure work is comprehensive, accurate, in keeping with the state of the art, and consistent with CAU goals. PER committees review various products, including data, documents, software/codes, analyses, and models. PER committees may also review technical briefings including Federal Facility Agreement and Consent Order (FFACO)-required presentations to the Nevadamore » Division of Environmental Protection (NDEP) and presentations supporting key technical decisions (e.g., investigation plans and approaches). PER committees provide technical recommendations to support regulatory decisions that are the responsibility of the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) and NDEP.« less

Outcomes of an Independent Review and Guidelines for the Implementation of a Program Review Model. Volume II. Technical Report.

ERIC Educational Resources Information Center

Carvell Education Managment Planning, Inc., Los Angeles, CA.

The second part of a report on a comprehensive review of the credit instructional programs offered by Pasadena City College (PCC), this volume contains a technical description of the data collection and assembly procedures used in the program review and provides guidelines for the implementation of the program review model. The first section…

Review of PREPA Technical Requirements for Interconnecting Wind and Solar Generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gevorgian, Vahan; Booth, Sarah

2013-11-01

The Puerto Rico Electric Power Authority developed the minimum technical requirements for interconnection of wind turbine generation and photovoltaic power plants. NREL has conducted a review of these requirements based on generic technical aspects and electrical characteristics of wind and photovoltaic power plants, and on existing requirements from other utilities (both U.S. and European).

14 CFR 414.19 - Technical criteria for reviewing a safety approval application.

Code of Federal Regulations, 2011 CFR

2011-01-01

...-developed criteria must define— (i) Design and minimum performance; (ii) Quality assurance system... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Technical criteria for reviewing a safety... AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING SAFETY APPROVALS Safety Approval Review and...

Space station attached payload program support

NASA Technical Reports Server (NTRS)

Estes, Maurice G., Jr.; Brown, Bardle D.

1989-01-01

The USRA is providing management and technical support for the peer review of the Space Station Freedom Attached Payload proposals. USRA is arranging for consultants to evaluate proposals, arranging meeting facilities for the reviewers to meet in Huntsville, Alabama and management of the actual review meetings. Assistance in developing an Experiment Requirements Data Base and Engineering/Technical Assessment support for the MSFC Technical Evaluation Team is also being provided. The results of the project will be coordinated into a consistent set of reviews and reports by USRA. The strengths and weaknesses analysis provided by the peer panel reviewers will by used NASA personnel in the selection of experiments for implementation on the Space Station Freedom.

1981 Bibliography of Technical Writing.

ERIC Educational Resources Information Center

Book, Virginia Alm; And Others

1982-01-01

Offers resources on technical writing published in 1981. Arranges the citations under the following categories: bibliographies, books, reviews, and articles on the profession; theory and philosophy; pedagogy; technical speech; research; designing degree programs; technical writing and the computer; writing technical articles and reports;…

The Effect of Technical Performance on Patient Outcomes in Surgery: A Systematic Review.

PubMed

Fecso, Andras B; Szasz, Peter; Kerezov, Georgi; Grantcharov, Teodor P

2017-03-01

Systematic review of the effect of intraoperative technical performance on patient outcomes. The operating room is a high-stakes, high-risk environment. As a result, the quality of surgical interventions affecting patient outcomes has been the subject of discussion and research for years. MEDLINE, EMBASE, PsycINFO, and Cochrane databases were searched. All surgical specialties were eligible for inclusion. Data were reviewed in regards to the methods by which technical performance was measured, what patient outcomes were assessed, and how intraoperative technical performance affected patient outcomes. Quality of evidence was assessed using the Medical Education Research Study Quality Instrument (MERSQI). Of the 12,758 studies initially identified, 24 articles (7775 total participants) were ultimately included in this review. Seventeen studies assessed the performance of the faculty alone, 2 assessed both the faculty and trainees, 1 assessed trainees alone, and in 4 studies, the level of the operating surgeon was not specified. In 18 studies, a performance assessment tool was used. Patient outcomes were evaluated using intraoperative complications, short-term morbidity, long-term morbidity, short-term mortality, and long-term mortality. The average MERSQI score was 11.67 (range 9.5-14.5). Twenty-one studies demonstrated that superior technical performance was related to improved patient outcomes. The results of this systematic review demonstrated that superior technical performance positively affects patient outcomes. Despite this initial evidence, more robust research is needed to directly assess intraoperative technical performance and its effect on postoperative patient outcomes using meaningful assessment instruments and reliable processes.

Chlordane (Technical)

Integrated Risk Information System (IRIS)

TOXICOLOGICAL REVIEW of CHLORDANE ( TECHNICAL ) ( CAS No . 12789 - 03 - 6 ) In Support of Summary Information on the Integrated Risk Information System ( IRIS ) December 1997 U.S . Environmental Protection Agency Washington , DC TABLE OF CONTENTS Authors and Reviewers . . . . . . . . . . . . .

23 CFR 636.305 - Can price information be provided to analysts who are reviewing technical proposals?

Code of Federal Regulations, 2013 CFR

2013-04-01

... OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Proposal Evaluation...? Normally, technical and price proposals are reviewed independently by separate evaluation teams. However...

23 CFR 636.305 - Can price information be provided to analysts who are reviewing technical proposals?

Code of Federal Regulations, 2012 CFR

2012-04-01

... OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Proposal Evaluation...? Normally, technical and price proposals are reviewed independently by separate evaluation teams. However...

23 CFR 636.305 - Can price information be provided to analysts who are reviewing technical proposals?

Code of Federal Regulations, 2010 CFR

2010-04-01

... OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Proposal Evaluation...? Normally, technical and price proposals are reviewed independently by separate evaluation teams. However...

23 CFR 636.305 - Can price information be provided to analysts who are reviewing technical proposals?

Code of Federal Regulations, 2014 CFR

2014-04-01

... OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Proposal Evaluation...? Normally, technical and price proposals are reviewed independently by separate evaluation teams. However...

23 CFR 636.305 - Can price information be provided to analysts who are reviewing technical proposals?

Code of Federal Regulations, 2011 CFR

2011-04-01

... OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Proposal Evaluation...? Normally, technical and price proposals are reviewed independently by separate evaluation teams. However...

48 CFR 815.404-1 - Proposal analysis techniques.

Code of Federal Regulations, 2010 CFR

2010-10-01

... technical reviews. (See 801.602-70.) (b) Contracting officers determine the level of technical analyses... under them, and contract modifications. Contracting officers must request technical analyses of the proposals from the appropriate technical personnel. The technical analyses must address, as a minimum, the...

48 CFR 815.404-1 - Proposal analysis techniques.

Code of Federal Regulations, 2011 CFR

2011-10-01

... technical reviews. (See 801.602-70.) (b) Contracting officers determine the level of technical analyses... under them, and contract modifications. Contracting officers must request technical analyses of the proposals from the appropriate technical personnel. The technical analyses must address, as a minimum, the...

1980 Bibliography of Technical Writing.

ERIC Educational Resources Information Center

Book, Virginia Alm; And Others

1981-01-01

Offers resources on technical writing that were published in 1980. Arranges the citations under 12 categories: bibliographies, books, reviews, and articles on theory and philosophy; pedagogy; writing technical articles and reports; research; technical writing and the computer; graphic/visual aids; correspondence; technical speech; and designing…

75 FR 31433 - Science Advisory Board Staff Office; Notification of a Public Meeting of the SAB Lead Review Panel

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-03

... Lead Review Panel to provide a consultation on EPA's draft technical analyses that will be used to...-to-face meeting to provide a consultation on EPA's draft technical analyses that will be used to... buildings. In the future, EPA will also develop draft technical analyses to support the development of lead...

Marketing information: The technical report as product

NASA Technical Reports Server (NTRS)

Stoher, F. F.; Pinelli, T. E.

1981-01-01

Technical reports constitute a product, the primary means for communicating the results of research to the user. The Langley scientific and technical information (STI) review and evaluation project undertook a review of the technical report as an effective product for information communication. Style manuals describing theory and practice in technical report preparation; publication manuals covering such factors as design, layout, and type style; and copies of technical reports were obtained from industrial, academic, governmental, and research organizations. Based on an analysis of this material, criteria will be established for the report components, for the relationship of the components within the report context, and for the overall report organization. The criteria will be used as bench marks and compared with the publication standards currently used to prepare NASA technical reports.

48 CFR 315.307 - Proposal revisions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... appropriate; and (2) An evaluation of technical factors by the technical evaluation panel, as necessary. The technical evaluation panel may rescore and re-rank technical proposals in the competitive range and prepare a technical evaluation report. To the extent practicable, the same evaluators who reviewed the...

76 FR 4115 - Request for the Technical Review of the Draft Current Intelligence Bulletin (CIB): Derivation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-24

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [Docket Number NIOSH-156] Request for the Technical Review of the Draft Current Intelligence Bulletin (CIB): Derivation... public review of the draft, Current Intelligence Bulletin (CIB): Derivation of Immediately Dangerous to...

76 FR 38200 - Notice of Submission of Proposed Information Collection to OMB; Public Housing Assessment System...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-29

... Proposed Information Collection to OMB; Public Housing Assessment System (PHAS) Appeals, Technical Reviews... Management and Budget (OMB) for review, as required by the Paperwork Reduction Act. The Department is... housing agencies (PHAs) may submit a request for a technical review, database adjustment or appeal. The...

75 FR 6030 - EPA Science Advisory Board Staff Office Request for Nominations of Experts for the SAB Lead (Pb...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-05

... requesting public nominations of experts to form an SAB Ad Hoc Panel to review EPA's draft technical analyses... residential dust. OPPT is developing draft technical analyses that will be used to support: (a) Possible... that the SAB conduct a review of these draft technical analyses. The SAB was established by 42 U.S.C...

Technical Review Guidelines for Environmental Impact Assessments in the Tourism, Energy and Mining Sectors

EPA Pesticide Factsheets

EPA coordinated a regional collaborative process with Central America and Dominican Republic Free Trade Agreement (CAFTA-DR) partners to develop Environmental Impact Assessment (EIA) Technical Review Guidelines for three sectors.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gonder, Jeff; Wood, Eric; Lammert, Michael

Jeff was invited to brief the EPA Mobile Sources Technical Review Subcommittee on considerations regarding potential energy and environmental considerations for connected and automated vehicles. For more information about the MSTRS see http://www2.epa.gov/caaac/mobile-sources-technical-review-subcommittee-mstrs-caaac.

The role of non-technical skills in surgery

PubMed Central

Agha, Riaz A.; Fowler, Alexander J.; Sevdalis, Nick

2015-01-01

Non-technical skills are of increasing importance in surgery and surgical training. A traditional focus on technical skills acquisition and competence is no longer enough for the delivery of a modern, safe surgical practice. This review discusses the importance of non-technical skills and the values that underpin successful modern surgical practice. This narrative review used a number of sources including written and online, there was no specific search strategy of defined databases. Modern surgical practice requires; technical and non-technical skills, evidence-based practice, an emphasis on lifelong learning, monitoring of outcomes and a supportive institutional and health service framework. Finally these requirements need to be combined with a number of personal and professional values including integrity, professionalism and compassionate, patient-centred care. PMID:26904193

Synthesis and Ligand Non-Innocence of Thiolate-Ligated (N4S) Iron(II) and Nickel(II) Bis(imino)pyridine Complexes

PubMed Central

Widger, Leland R.; Jiang, Yunbo; Siegler, Maxime; Kumar, Devesh; Latifi, Reza; de Visser, Sam P.; Jameson, Guy N.L.; Goldberg, David P.

2013-01-01

The known iron(II) complex [FeII(LN3S)(OTf)] (1) was used as starting material to prepare the new biomimetic (N4S(thiolate)) iron(II) complexes [FeII(LN3S)(py)](OTf) (2) and [FeII(LN3S)(DMAP)](OTf) (3), where LN3S is a tetradentate bis(imino)pyridine (BIP) derivative with a covalently tethered phenylthiolate donor. These complexes were characterized by X-ray crystallography, UV-vis, 1H NMR, and Mössbauer spectroscopy, as well as electrochemistry. A nickel(II) analogue, [NiII(LN3S)](BF4) (5), was also synthesized and characterized by structural and spectroscopic methods. Cyclic voltammetric studies showed 1 – 3 and 5 undergo a single reduction process with E1/2 between −0.9 to −1.2 V versus Fc+/Fc. Treatment of 3 with 0.5% Na/Hg amalgam gave the mono-reduced complex [Fe(LN3S)(DMAP)]0 (4), which was characterized by X-ray crystallography, UV-vis, EPR (g = [2.155, 2.057, 2.038]) and Mössbauer (δ = 0.33 mm s−1; ΔEQ = 2.04 mm s−1) spectroscopies. Computational methods (DFT) were employed to model complexes 3 – 5. The combined experimental and computational studies show that 1 – 3 are 5-coordinate, high-spin (S = 2) FeII complexes, whereas 4 is best described as a 5-coordinate, intermediate-spin (S = 1) FeII complex antiferromagnetically coupled to a ligand radical. This unique electronic configuration leads to an overall doublet spin (Stotal = ½) ground state. Complexes 2 and 3 are shown to react with O2 to give S-oxygenated products, as previously reported for 1. In contrast, the mono-reduced 4 appears to react with O2 to give a mixture of S- and Fe-oxygenates. The nickel(II) complex 5 does not react with O2, and even when the mono-reduced nickel complex is produced, it appears to undergo only outer-sphere oxidation with O2. PMID:23992096

A review and evaluation of the Langley Research Center's Scientific and Technical Information Program: Results of phase 6: The technical report. A survey and analysis

NASA Technical Reports Server (NTRS)

Mccullough, R. A.; Pinelli, T. E.; Pilley, D. D.; Stohrer, F. F.

1982-01-01

Current practice and usage using selected technical reports; literature relative to the sequential, language, and presentation components of technical reports; and NASA technical report publications standards are discussed. The effctiveness of the technical report as a product for information dissemination is considered.

32 CFR 203.10 - Eligible activities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... with technical reports that summarize data and support cleanup decisions. Technical assistance may be provided to review plans and interpret technical reports for community members of RABs and TRCs. These...) MISCELLANEOUS TECHNICAL ASSISTANCE FOR PUBLIC PARTICIPATION (TAPP) IN DEFENSE ENVIRONMENTAL RESTORATION...

32 CFR 203.10 - Eligible activities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... with technical reports that summarize data and support cleanup decisions. Technical assistance may be provided to review plans and interpret technical reports for community members of RABs and TRCs. These...) MISCELLANEOUS TECHNICAL ASSISTANCE FOR PUBLIC PARTICIPATION (TAPP) IN DEFENSE ENVIRONMENTAL RESTORATION...

32 CFR 203.10 - Eligible activities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... with technical reports that summarize data and support cleanup decisions. Technical assistance may be provided to review plans and interpret technical reports for community members of RABs and TRCs. These...) MISCELLANEOUS TECHNICAL ASSISTANCE FOR PUBLIC PARTICIPATION (TAPP) IN DEFENSE ENVIRONMENTAL RESTORATION...

40 CFR 35.4005 - What is a Technical Assistance Grant?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Technical Assistance Grant? A Technical Assistance Grant (TAG) provides money for your group to obtain... technical advisors to help you interpret and comment on site-related information and decisions. Examples of how a technical advisor can help your group include, but are not limited to: (a) Reviewing preliminary...

40 CFR 35.4005 - What is a Technical Assistance Grant?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Technical Assistance Grant? A Technical Assistance Grant (TAG) provides money for your group to obtain... technical advisors to help you interpret and comment on site-related information and decisions. Examples of how a technical advisor can help your group include, but are not limited to: (a) Reviewing preliminary...

40 CFR 35.4005 - What is a Technical Assistance Grant?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Technical Assistance Grant? A Technical Assistance Grant (TAG) provides money for your group to obtain... technical advisors to help you interpret and comment on site-related information and decisions. Examples of how a technical advisor can help your group include, but are not limited to: (a) Reviewing preliminary...

40 CFR 35.4005 - What is a Technical Assistance Grant?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Technical Assistance Grant? A Technical Assistance Grant (TAG) provides money for your group to obtain... technical advisors to help you interpret and comment on site-related information and decisions. Examples of how a technical advisor can help your group include, but are not limited to: (a) Reviewing preliminary...

A Model for Joint Software Reviews

DTIC Science & Technology

1998-10-01

CEPMAN 1, 1996; Gabb, 1997], and with the growing popularity of outsourcing, they are becoming more important in the commercial sector [ ISO /IEC 12207 ...technical and management reviews [MIL-STD-498, 1996; ISO /IEC 12207 , 1995]. Management reviews occur after technical reviews, and are focused on the cost...characteristics, Standard (No. ISO /IEC 9126-1). [ ISO /IEC 12207 , 1995] Information Technology Software Life Cycle Processes, Standard (No. ISO /IEC 12207

Do failures in non-technical skills contribute to fatal medical accidents in Japan? A review of the 2010–2013 national accident reports

PubMed Central

Uramatsu, Masashi; Fujisawa, Yoshikazu; Mizuno, Shinya; Souma, Takahiro; Komatsubara, Akinori; Miki, Tamotsu

2017-01-01

Objectives We sought to clarify how large a proportion of fatal medical accidents can be considered to be caused by poor non-technical skills, and to support development of a policy to reduce number of such accidents by making recommendations about possible training requirements. Design Summaries of reports of fatal medical accidents, published by the Japan Medical Safety Research Organization, were reviewed individually. Three experienced clinicians and one patient safety expert conducted the reviews to determine the cause of death. Views of the patient safety expert were given additional weight in the overall determination. Setting A total of 73 summary reports of fatal medical accidents were reviewed. These reports had been submitted by healthcare organisations across Japan to the Japan Medical Safety Research Organization between April 2010 and March 2013. Primary and secondary outcome measures The cause of death in fatal medical accidents, categorised into technical skills, non-technical skills and inevitable progress of disease were evaluated. Non-technical skills were further subdivided into situation awareness, decision making, communication, team working, leadership, managing stress and coping with fatigue. Results Overall, the cause of death was identified as non-technical skills in 34 cases (46.6%), disease progression in 33 cases (45.2%) and technical skills in two cases (5.5%). In two cases, no consensual determination could be achieved. Further categorisation of cases of non-technical skills were identified as 14 cases (41.2%) of problems with situation awareness, eight (23.5%) with team working and three (8.8%) with decision making. These three subcategories, or combinations of them, were identified as the cause of death in 33 cases (97.1%). Conclusions Poor non-technical skills were considered to be a significant cause of adverse events in nearly half of the fatal medical accidents examined. Improving non-technical skills may be effective for reducing accidents, and training in particular subcategories of non-technical skills may be especially relevant. PMID:28209605

75 FR 47306 - Office of the Assistant Secretary for Planning and Evaluation; Technical Review Panel on the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-05

... Marian Robinson found in the Federal Register (FR) on July 30, 2010, entitled ``Technical Review Panel on... and should include the e-mail address for Marian Robinson ( marian.robinson@hhs.gov ). Applicability...

Preliminary technical results review of FY81 experiments. Volume 1: Fiscal year 1981/82 spring small grains pilot experiment. [Canada and the United States

NASA Technical Reports Server (NTRS)

1981-01-01

Technical progress made in the foreign commodity production forecasting for the advancement of spring small grains (SSG) area estimation is reported with emphasis on results achieved since the last AgRISTARS level semiannual review. Major objectives and accomplishments are reviewed and the experiment is described. The technical approach data assessment, and data systems used are considered. Results of the group approach comparison study are presented along with preliminary aggregation results for SSG processing procedures. The outlook for the future is assessed.

Technical report writing

NASA Technical Reports Server (NTRS)

Vidoli, Carol A.

1992-01-01

This manual covers the fundamentals of organizing, writing, and reviewing NASA technical reports. It was written to improve the writing skills of LeRC technical authors and the overall quality of their reports.

48 CFR 952.242-70 - Technical direction.

Code of Federal Regulations, 2011 CFR

2011-10-01

.... (3) Reviewing and, where required by the contract, approving, technical reports, drawings... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Technical direction. 952... FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.242-70 Technical...

48 CFR 952.242-70 - Technical direction.

Code of Federal Regulations, 2012 CFR

2012-10-01

.... (3) Reviewing and, where required by the contract, approving, technical reports, drawings... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Technical direction. 952... FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.242-70 Technical...

48 CFR 952.242-70 - Technical direction.

Code of Federal Regulations, 2014 CFR

2014-10-01

.... (3) Reviewing and, where required by the contract, approving, technical reports, drawings... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Technical direction. 952... FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.242-70 Technical...

48 CFR 952.242-70 - Technical direction.

Code of Federal Regulations, 2013 CFR

2013-10-01

.... (3) Reviewing and, where required by the contract, approving, technical reports, drawings... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Technical direction. 952... FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.242-70 Technical...

77 FR 53912 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; H-1B...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-04

... for OMB Review; Comment Request; H-1B Technical Skills Training Grants and H-1B Jobs and Innovation..., ``H-1B Technical Skills Training Grants and H-1B Jobs and Innovation Accelerator Challenge Grants,'' to the Office of Management and Budget (OMB) for review and approval for use in accordance with the...

A Comprehensive Review of Selected Business Programs in Community Colleges and Area Vocational-Technical Centers. Program Review Report.

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee. Div. of Vocational, Adult, and Community Education.

In 1988, a review was conducted of the business component of associate in arts and associate in science (AS) degree programs, and of the certificate programs in business in Florida community colleges and area vocational-technical centers. Focusing primarily on business programs in marketing, general business management, and small business…

A systematic literature review on security and privacy of electronic health record systems: technical perspectives.

PubMed

Rezaeibagha, Fatemeh; Win, Khin Than; Susilo, Willy

Even though many safeguards and policies for electronic health record (EHR) security have been implemented, barriers to the privacy and security protection of EHR systems persist. This article presents the results of a systematic literature review regarding frequently adopted security and privacy technical features of EHR systems. Our inclusion criteria were full articles that dealt with the security and privacy of technical implementations of EHR systems published in English in peer-reviewed journals and conference proceedings between 1998 and 2013; 55 selected studies were reviewed in detail. We analysed the review results using two International Organization for Standardization (ISO) standards (29100 and 27002) in order to consolidate the study findings. Using this process, we identified 13 features that are essential to security and privacy in EHRs. These included system and application access control, compliance with security requirements, interoperability, integration and sharing, consent and choice mechanism, policies and regulation, applicability and scalability and cryptography techniques. This review highlights the importance of technical features, including mandated access control policies and consent mechanisms, to provide patients' consent, scalability through proper architecture and frameworks, and interoperability of health information systems, to EHR security and privacy requirements.

Using Model-Based System Engineering to Provide Artifacts for NASA Project Life-Cycle and Technical Reviews Presentation

NASA Technical Reports Server (NTRS)

Parrott, Edith L.; Weiland, Karen J.

2017-01-01

This is the presentation for the AIAA Space conference in September 2017. It highlights key information from Using Model-Based Systems Engineering to Provide Artifacts for NASA Project Life-cycle and Technical Reviews paper.

Data Requirements Review Boards and Their Importance

DTIC Science & Technology

2016-02-01

data: technical data, which are recorded technical or scientific information (not including computer software), and contractual or financial and...navy.mil. References for This Article and Other Useful Sources NAVAIRINST 4200.21E—Naval Air SystemsCommand Data Requirements Review Board DoD

Rationale for a Threshold Limit Value (TLV)R for JP-4/Jet B Wide Cut Aviation Turbine Fuel.

DTIC Science & Technology

1983-04-01

Additional copies may be purchased from: National Technical Information Service 5285 Port Royal Road Springfield, Virginia 22161 Government agencies...Cameron Station Alexandria, Virginia 22314 This report has been reviewed by the Public Affairs Office and is releasable to the National Technical...Information Service (NTIS). At NTIS, it will be available to the general public, including foreign nations . This technical report has been reviewed and is

HOPE information system review

NASA Astrophysics Data System (ADS)

Suzuki, Yoshiaki; Nishiyama, Kenji; Ono, Shuuji; Fukuda, Kouin

1992-08-01

An overview of the review conducted on H-2 Orbiting Plane (HOPE) is presented. A prototype model was constructed by inputting various technical information proposed by related laboratories. Especially operation flow which enables understanding of correlation between various analysis items, judgement criteria, technical data, and interfaces with others was constructed. Technical information data base and retrieval systems were studied. A Macintosh personal computer was selected for information shaping because of its excellent function, performance, operability, and software completeness.

Technical evaluation of RETS-required reports for Browns Ferry Nuclear Power Station, Units 1, 2, and 3, for 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Young, T.E.; Magleby, E.H.

1985-09-06

A review was performed of reports required by federal regulations and the plant-specific radiological effluent technical specifications (RETS) for operations conducted at Tennessee Valley Authority's Browns Ferry Nuclear Station, Units 1, 2, and 3, during 1983. The two periodic reports reviewed were (a) the Effluents and Waste Disposal Semiannual Report, First Half 1983 and (b) the Effluents and Waste Disposal Semiannual Report, Second Half 1983. The principal review guidelines were the plant's specific RETs and NRC guidance given in NUREG-0133, ''Preparation of Radiological Effluent Technical Specifications for Nuclear Power Plants.'' The Licensee's submitted reports were found to be reasonably completemore » and consistent with the review guidelines.« less

A Study of Technical Engineering Peer Reviews at NASA

NASA Technical Reports Server (NTRS)

Chao, Lawrence P.; Tumer, Irem Y.; Bell, David G.

2003-01-01

This report describes the state of practices of design reviews at NASA and research into what can be done to improve peer review practices. There are many types of reviews at NASA: required and not, formalized and informal, programmatic and technical. Standing project formal reviews such as the Preliminary Design Review and Critical Design Review are a required part of every project and mission development. However, the technical, engineering peer reviews that support teams' work on such projects are informal, some times ad hoc, and inconsistent across the organization. The goal of this work is to identify best practices and lessons learned from NASA's experience, supported by academic research and methodologies to ultimately improve the process. This research has determined that the organization, composition, scope, and approach of the reviews impact their success. Failure Modes and Effects Analysis (FMEA) can identify key areas of concern before or in the reviews. Product definition tools like the Project Priority Matrix, engineering-focused Customer Value Chain Analysis (CVCA), and project or system-based Quality Function Deployment (QFD) help prioritize resources in reviews. The use of information technology and structured design methodologies can strengthen the engineering peer review process to help NASA work towards error-proofing the design process.

7 CFR 1728.50 - Removal of an item from listing or technical acceptance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... equipment will be notified in writing of a proposal to remove such item from the listing or technical... unanimous, the item will be referred to Technical Standards Committee “B.” Written notice of Technical...” decision, a sponsor may appeal in writing to Technical Standards Committee “B” to review Committee “A's...

Ozone (O3) Standards - Other Technical Documents from the Review Completed in 2015

EPA Pesticide Factsheets

These memoranda were each sent in to the Ozone NAAQS Review Docket, EPA-HQ-OAR-2008-0699, after the proposed rule was published. They present technical data on the methods, monitoring stations, and metrics used to estimate ozone concentrations.

78 FR 60244 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-01

... collections are best assured of having their full effect if received within 30 days of this notification.... Rural Utilities Service (RUS) announced the application window for funding Rural Libraries, Technical... three funding opportunities were reviewed and awards were made for Satellite and Technical Assistance...

EUV mask defect inspection and defect review strategies for EUV pilot line and high volume manufacturing

NASA Astrophysics Data System (ADS)

Chan, Y. David; Rastegar, Abbas; Yun, Henry; Putna, E. Steve; Wurm, Stefan

2010-04-01

Reducing mask blank and patterned mask defects is the number one challenge for extreme ultraviolet lithography. If the industry succeeds in reducing mask blank defects at the required rate of 10X every year for the next 2-3 years to meet high volume manufacturing defect requirements, new inspection and review tool capabilities will soon be needed to support this goal. This paper outlines the defect inspection and review tool technical requirements and suggests development plans to achieve pilot line readiness in 2011/12 and high volume manufacturing readiness in 2013. The technical specifications, tooling scenarios, and development plans were produced by a SEMATECH-led technical working group with broad industry participation from material suppliers, tool suppliers, mask houses, integrated device manufacturers, and consortia. The paper summarizes this technical working group's assessment of existing blank and mask inspection/review infrastructure capabilities to support pilot line introduction and outlines infrastructure development requirements and tooling strategies to support high volume manufacturing.

Report on the technical review workshop on the reference dose for Aroclor 1016. Held in Washington, DC on May 24-25, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-11-01

The report includes information and material from a technical review workshop organized by the U.S. Environmental Protection Agency`s (EPA`s) Risk Assessment Forum for EPA`s Reference Dose/Reference Concentration (RfD/RfC) Work Group. The meeting was held in Washington, DC, at the Barcelo Washington Hotel on May 24-25, 1994. The subject of the technical review was the Integrated Risk Information System (IRIS) RfD entry for Aroclor 1016, a polychlorinated biphenyl (PCB). The expert technical review panel was convened to independently evaluate whether the RfD for Aroclor 1016 is based on a scientifically responsible analysis that represents full consideration of the available data andmore » clean articulation of that analysis in the IRIS RfD entry. EPA also requested panel members to consider four broad options for the Aroclor 1016 RfD as potential recommendations to the RfD/RfC Work Group.« less

Guiding bioprocess design by microbial ecology.

PubMed

Volmer, Jan; Schmid, Andreas; Bühler, Bruno

2015-06-01

Industrial bioprocess development is driven by profitability and eco-efficiency. It profits from an early stage definition of process and biocatalyst design objectives. Microbial bioprocess environments can be considered as synthetic technical microbial ecosystems. Natural systems follow Darwinian evolution principles aiming at survival and reproduction. Technical systems objectives are eco-efficiency, productivity, and profitable production. Deciphering technical microbial ecology reveals differences and similarities of natural and technical systems objectives, which are discussed in this review in view of biocatalyst and process design and engineering strategies. Strategies for handling opposing objectives of natural and technical systems and for exploiting and engineering natural properties of microorganisms for technical systems are reviewed based on examples. This illustrates the relevance of considering microbial ecology for bioprocess design and the potential for exploitation by synthetic biology strategies. Copyright © 2015 Elsevier Ltd. All rights reserved.

Urology technical and non-technical skills development: the emerging role of simulation.

PubMed

Rashid, Prem; Gianduzzo, Troy R J

2016-04-01

To review the emerging role of technical and non-technical simulation in urological education and training. A review was conducted to examine the current role of simulation in urology training. A PUBMED search of the terms 'urology training', 'urology simulation' and 'urology education' revealed 11,504 titles. Three hundred and fifty-seven abstracts were identified as English language, peer reviewed papers pertaining to the role of simulation in urology and related topics. Key papers were used to explore themes. Some cross-referenced papers were also included. There is an ongoing need to ensure that training time is efficiently utilised while ensuring that optimal technical and non-technical skills are achieved. Changing working conditions and the need to minimise patient harm by inadvertent errors must be taken into account. Simulation models for specific technical aspects have been the mainstay of graduated step-wise low and high fidelity training. Whole scenario environments as well as non-technical aspects can be slowly incorporated into the curriculum. Doing so should also help define what have been challenging competencies to teach and evaluate. Dedicated time, resources and trainer up-skilling are important. Concurrent studies are needed to help evaluate the effectiveness of introducing step-wise simulation for technical and non-technical competencies. Simulation based learning remains the best avenue of progressing surgical education. Technical and non-technical simulation could be used in the selection process. There are good economic, logistic and safety reasons to pursue the process of ongoing development of simulation co-curricula. While the role of simulation is assured, its progress will depend on a structured program that takes advantage of what can be delivered via this medium. Overall, simulation can be developed further for urological training programs to encompass technical and non-technical skill development at all stages, including recertification. © 2015 The Authors BJU International © 2015 BJU International Published by John Wiley & Sons Ltd.

48 CFR 2052.215-71 - Project officer authority.

Code of Federal Regulations, 2012 CFR

2012-10-01

... of the work description. (3) Review and, where required by the contract, approve technical reports... subject to the technical direction of the NRC project officer. The term technical direction is defined to include the following: (1) Technical direction to the contractor which shifts work emphasis between areas...

48 CFR 2052.215-71 - Project officer authority.

Code of Federal Regulations, 2011 CFR

2011-10-01

... of the work description. (3) Review and, where required by the contract, approve technical reports... subject to the technical direction of the NRC project officer. The term technical direction is defined to include the following: (1) Technical direction to the contractor which shifts work emphasis between areas...

48 CFR 2052.215-71 - Project officer authority.

Code of Federal Regulations, 2013 CFR

2013-10-01

... of the work description. (3) Review and, where required by the contract, approve technical reports... subject to the technical direction of the NRC project officer. The term technical direction is defined to include the following: (1) Technical direction to the contractor which shifts work emphasis between areas...

48 CFR 2052.215-71 - Project officer authority.

Code of Federal Regulations, 2014 CFR

2014-10-01

... of the work description. (3) Review and, where required by the contract, approve technical reports... subject to the technical direction of the NRC project officer. The term technical direction is defined to include the following: (1) Technical direction to the contractor which shifts work emphasis between areas...

Review Of Piping And Pressure Vessel Code Design Criteria. Technical Report 217.

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

1969-04-18

This Technical Report summarizes a review of the design philosophies and criteria of the ASME Boiler and Pressure Vessel Code and the USASI Code for Pressure Piping. It traces the history of the Codes since their inception and critically reviews their present status. Recommendations are made concerning the applicability of the Codes to the special needs of LMFBR liquid sodium piping.

Proceedings of the CASE Adoption Workshop Held in Pittsburgh, Pennsylvania on 13-14 November 1990

DTIC Science & Technology

1992-05-01

position. It Is published in the interest of scientific and technical information exchange. Review and Approval This report has been reviewed and is...available through the Defense Technical Information Center. DTIC provides access so and transr of scientific and technical information for DoD... Metthods and Tools $1,850 P-Cube Corporation 572 East Lamibert Rd CASEbase (a PC-based CASE database) $495 Brea, CA 92621 (714) 990-3169 Foresite

ATS-6 - Technical aspects of the Health/Education Telecommunications Experiment

NASA Technical Reports Server (NTRS)

Boor, J. L.; Braunstein, J.; Janky, J. M.; Ogden, D.; Potter, J. G.; Harper, E. L.; Volkmer, E.; Whalen, A. A.; Henderson, E.; Hupe, H. H.

1975-01-01

An overview is given of the HET experiment on ATS-6. The paper is divided into nine parts, including a technical overview, a preliminary evaluation of the HET demonstration, a review of operations at the Denver uplink terminal, a discussion of remote ground terminals, a review of C-band comprehensive terminals and of S-band comprehensive terminals, and parts devoted to general network operations, technical management and effectiveness of the network, and the site equipment operator.

Report-reading patterns of technical managers and nonmanagers

NASA Technical Reports Server (NTRS)

Pinelli, T. E.; Cordle, V. M.; Glassman, M.; Vondran, R. F., Jr.

1984-01-01

A survey to determine the review and reading processes used by technical managers and nonmanagers indicates that the summary, abstract, conclusion, title page, and introduction are the components used most frequently by both groups to decide whether to read a NASA technical report. In the review process, significantly more managers than nonmanagers use the summary and conclusion, whereas significantly more nonmanagers use the abstract and title page. The most common sequence of review consists of the title page, abstract, and summary, in that order, for both groups. In the reading process, the conclusion, results and discussion, and summary are the components read by the highest percentage of both groups.

42 CFR 52h.4 - Composition of peer review groups.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PEER REVIEW OF RESEARCH GRANT APPLICATIONS AND RESEARCH AND DEVELOPMENT CONTRACT PROJECTS § 52h.4... training and experience in relevant scientific or technical fields, or upon their qualifications as..., taking into account, among other factors: (1) The level of formal scientific or technical education...

49 CFR 552.6 - Technical review.

Code of Federal Regulations, 2014 CFR

2014-10-01

... petition. The technical review may consist of an analysis of the material submitted, together with information already in the possession of the agency. It may also include the collection of additional information, or a public meeting in accordance with § 552.7. [60 FR 17267, Apr. 5, 1995] ...

75 FR 52737 - Meeting of the Mobile Sources Technical Review Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-27

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9193-9] Meeting of the Mobile Sources Technical Review... Federal Advisory Committee Act, Public Law 92- 463, notice is hereby given that the Mobile Sources... the Subcommittee's Web Site: http://www.epa.gov/air/caaac/mobile_sources.html . MSTRS listserver...

76 FR 58275 - Meeting of the Mobile Sources Technical Review Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-20

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9466-9] Meeting of the Mobile Sources Technical Review... Federal Advisory Committee Act, Public Law 92- 463, notice is hereby given that the Mobile Sources... the Subcommittee's Web site: http://www.epa.gov/air/caaac/mobile_sources.html . MSTRS listserver...

40 CFR 35.4005 - What is a Technical Assistance Grant?

Code of Federal Regulations, 2010 CFR

2010-07-01

... public participation in decision making at eligible sites. A TAG allows your group to procure independent... Technical Assistance Grant? A Technical Assistance Grant (TAG) provides money for your group to obtain... how a technical advisor can help your group include, but are not limited to: (a) Reviewing preliminary...

Vocational-Technical Education Financial Study. Executive Summary.

ERIC Educational Resources Information Center

Indiana State Board of Vocational and Technical Education, Indianapolis.

A review of Indiana's current system of financing public vocational-technical education was limited to these concerns: the resource needs of vocational-technical education to keep the current delivery system up-to-date and the resources necessary to expand vocational-technical education services to those not being served. Although the current…

76 FR 77832 - Availability of Draft NTP Technical Reports; Request for Comments; Announcement of a Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-14

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Availability of Draft NTP Technical Reports; Request for Comments; Announcement of a Public Meeting To Peer Review Draft NTP Technical Reports AGENCY: National... Meeting. SUMMARY: The NTP announces the availability of seven draft NTP Technical Reports (TRs...

Do failures in non-technical skills contribute to fatal medical accidents in Japan? A review of the 2010-2013 national accident reports.

PubMed

Uramatsu, Masashi; Fujisawa, Yoshikazu; Mizuno, Shinya; Souma, Takahiro; Komatsubara, Akinori; Miki, Tamotsu

2017-02-16

We sought to clarify how large a proportion of fatal medical accidents can be considered to be caused by poor non-technical skills, and to support development of a policy to reduce number of such accidents by making recommendations about possible training requirements. Summaries of reports of fatal medical accidents, published by the Japan Medical Safety Research Organization, were reviewed individually. Three experienced clinicians and one patient safety expert conducted the reviews to determine the cause of death. Views of the patient safety expert were given additional weight in the overall determination. A total of 73 summary reports of fatal medical accidents were reviewed. These reports had been submitted by healthcare organisations across Japan to the Japan Medical Safety Research Organization between April 2010 and March 2013. The cause of death in fatal medical accidents, categorised into technical skills, non-technical skills and inevitable progress of disease were evaluated. Non-technical skills were further subdivided into situation awareness, decision making, communication, team working, leadership, managing stress and coping with fatigue. Overall, the cause of death was identified as non-technical skills in 34 cases (46.6%), disease progression in 33 cases (45.2%) and technical skills in two cases (5.5%). In two cases, no consensual determination could be achieved. Further categorisation of cases of non-technical skills were identified as 14 cases (41.2%) of problems with situation awareness, eight (23.5%) with team working and three (8.8%) with decision making. These three subcategories, or combinations of them, were identified as the cause of death in 33 cases (97.1%). Poor non-technical skills were considered to be a significant cause of adverse events in nearly half of the fatal medical accidents examined. Improving non-technical skills may be effective for reducing accidents, and training in particular subcategories of non-technical skills may be especially relevant. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

A Review on Technical and Clinical Impact of Microsoft Kinect on Physical Therapy and Rehabilitation

PubMed Central

Mousavi Hondori, Hossein; Khademi, Maryam

2014-01-01

This paper reviews technical and clinical impact of the Microsoft Kinect in physical therapy and rehabilitation. It covers the studies on patients with neurological disorders including stroke, Parkinson's, cerebral palsy, and MS as well as the elderly patients. Search results in Pubmed and Google scholar reveal increasing interest in using Kinect in medical application. Relevant papers are reviewed and divided into three groups: (1) papers which evaluated Kinect's accuracy and reliability, (2) papers which used Kinect for a rehabilitation system and provided clinical evaluation involving patients, and (3) papers which proposed a Kinect-based system for rehabilitation but fell short of providing clinical validation. At last, to serve as technical comparison to help future rehabilitation design other sensors similar to Kinect are reviewed. PMID:27006935

Technical aspects of CT imaging of the spine.

PubMed

Tins, Bernhard

2010-11-01

This review article discusses technical aspects of computed tomography (CT) imaging of the spine. Patient positioning, and its influence on image quality and movement artefact, is discussed. Particular emphasis is placed on the choice of scan parameters and their relation to image quality and radiation burden to the patient. Strategies to reduce radiation burden and artefact from metal implants are outlined. Data acquisition, processing, image display and steps to reduce artefact are reviewed. CT imaging of the spine is put into context with other imaging modalities for specific clinical indications or problems. This review aims to review underlying principles for image acquisition and to provide a rough guide for clinical problems without being prescriptive. Individual practice will always vary and reflect differences in local experience, technical provisions and clinical requirements.

A Review on Technical and Clinical Impact of Microsoft Kinect on Physical Therapy and Rehabilitation.

PubMed

Mousavi Hondori, Hossein; Khademi, Maryam

2014-01-01

This paper reviews technical and clinical impact of the Microsoft Kinect in physical therapy and rehabilitation. It covers the studies on patients with neurological disorders including stroke, Parkinson's, cerebral palsy, and MS as well as the elderly patients. Search results in Pubmed and Google scholar reveal increasing interest in using Kinect in medical application. Relevant papers are reviewed and divided into three groups: (1) papers which evaluated Kinect's accuracy and reliability, (2) papers which used Kinect for a rehabilitation system and provided clinical evaluation involving patients, and (3) papers which proposed a Kinect-based system for rehabilitation but fell short of providing clinical validation. At last, to serve as technical comparison to help future rehabilitation design other sensors similar to Kinect are reviewed.

Technical and tactical skills related to performance levels in tennis: A systematic review.

PubMed

Kolman, Nikki S; Kramer, Tamara; Elferink-Gemser, Marije T; Huijgen, Barbara C H; Visscher, Chris

2018-06-11

The aim of this systematic review is to provide an overview of outcome measures and instruments identified in the literature for examining technical and tactical skills in tennis related to performance levels. Such instruments can be used to identify talent or the specific skill development training needs of particular players. Searches for this review were conducted using the PubMed, Web of Science, and PsycInfo databases. Out of 733 publications identified through these searches, 40 articles were considered relevant and included in this study. They were divided into three categories: (1) technical skills, (2) tactical skills and (3) integrated technical and tactical skills. There was strong evidence that technical skills (ball velocity and to a lesser extent ball accuracy) and tactical skills (decision making, anticipation, tactical knowledge and visual search strategies) differed among players according to their performance levels. However, integrated measurement of these skills is required, because winning a point largely hinges on a tactical decision to perform a particular stroke (i.e., technical execution). Therefore, future research should focus on examining the relationship between these skills and tennis performance and on the development of integrated methods for measuring these skills.

14 CFR 414.19 - Technical criteria for reviewing a safety approval application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Technical criteria for reviewing a safety approval application. 414.19 Section 414.19 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL... regulations. (2) Government-developed or adopted standards. (3) Industry consensus performance-based criteria...

Analysis of Florida Department of Transportation transit corridor program/projects : technical memorandum number one - review and summary of transit corridor plans

DOT National Transportation Integrated Search

2001-05-01

The purpose of this project was to undertake a consolidated comprehensive review of the Florida Department of Transportation Transit Corridor Program. Technical Memorandum Number One provides a summary of all transit corridor projects either under wa...

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

48 CFR 801.602-79 - Processing solicitations and contract documents for legal or technical review-Veterans Benefits...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Processing solicitations and contract documents for legal or technical review-Veterans Benefits Administration. 801.602-79 Section 801.602-79 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL...

48 CFR 801.602-80 - Legal and technical review-Office of Construction and Facilities Management and National Cemetery...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Legal and technical review... 801.602-80 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and...

10 CFR 1303.101 - Scope

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Scope 1303.101 Section 1303.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.101 Scope This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding public access to...

10 CFR 1303.114 - Appeals.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Appeals. 1303.114 Section 1303.114 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.114 Appeals. (a)(1) Appeals of adverse... Executive Director: (i) By mail to: U.S. Nuclear Waste Technical Review Board, 2300 Clarendon Boulevard...

10 CFR 1303.101 - Scope

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Scope 1303.101 Section 1303.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.101 Scope This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding public access to...

10 CFR 1303.101 - Scope

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Scope 1303.101 Section 1303.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.101 Scope This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding public access to...

10 CFR 1303.114 - Appeals.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Appeals. 1303.114 Section 1303.114 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.114 Appeals. (a)(1) Appeals of adverse... Executive Director: (i) By mail to: U.S. Nuclear Waste Technical Review Board, 2300 Clarendon Boulevard...

10 CFR 1303.101 - Scope

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Scope 1303.101 Section 1303.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.101 Scope This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding public access to...

10 CFR 1303.101 - Scope

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Scope 1303.101 Section 1303.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.101 Scope This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding public access to...

10 CFR 1303.114 - Appeals.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Appeals. 1303.114 Section 1303.114 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.114 Appeals. (a)(1) Appeals of adverse... Executive Director: (i) By mail to: U.S. Nuclear Waste Technical Review Board, 2300 Clarendon Boulevard...

10 CFR 1303.114 - Appeals.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Appeals. 1303.114 Section 1303.114 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.114 Appeals. (a)(1) Appeals of adverse... Executive Director: (i) By mail to: U.S. Nuclear Waste Technical Review Board, 2300 Clarendon Boulevard...

10 CFR 1303.114 - Appeals.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Appeals. 1303.114 Section 1303.114 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.114 Appeals. (a)(1) Appeals of adverse... Executive Director: (i) By mail to: U.S. Nuclear Waste Technical Review Board, 2300 Clarendon Boulevard...

Texas State Technical College Review.

ERIC Educational Resources Information Center

Aumack, Bruce; Blake, Larry J.

Texas educational legislation for 1991 required the Texas Higher Education Coordinating Board (THECB) to review the operations of, and the continuing need for, each of the four main campuses and five extension centers of the Texas State Technical College System (TSTCS), and to make recommendations concerning the facilities' continuation and/or…

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

77 FR 13318 - Meeting of the Mobile Sources Technical Review Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-06

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9643-6] Meeting of the Mobile Sources Technical Review... Federal Advisory Committee Act, Public Law 92- 463, notice is hereby given that the Mobile Sources... Air Act Advisory Committee. This is an open meeting. The meeting will include discussion of current...

Archival Stability of Microfilm--A Technical Review.

ERIC Educational Resources Information Center

Materazzi, Albert R.

The purpose of this report is to acquaint all personnel with some technical aspects of micrographics. The various film types used in the production of microfiche are discussed, including silver halide, diazo, and vesicular films. Other imaging systems used in micrographics are reviewed, and a basic introduction to sensitometry is given. The…

33 CFR 385.21 - Quality control.

Code of Federal Regulations, 2012 CFR

2012-07-01

... will be produced by a Project Delivery Team. The quality control plan shall be included in the Project... Corps of Engineers and the non-Federal sponsor shall establish a Technical Review Team to conduct.... The members of the Technical Review Team shall be independent of the Project Delivery Team and the...

76 FR 19095 - Meeting of the Mobile Sources Technical Review Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-06

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9290-8] Meeting of the Mobile Sources Technical Review... Federal Advisory Committee Act, Public Law 92- 463, notice is hereby given that the Mobile Sources... Subcommittee's Web site: http://www.epa.gov/air/caaac/mobile_sources.html . MSTRS listserver subscribers will...

Report to the Governor and the 1989 Minnesota Legislature. Technical Report.

ERIC Educational Resources Information Center

Minnesota Higher Education Coordinating Board, St. Paul.

This technical report provides a detailed presentation of the status of Minnesota postsecondary education, summarizes policy issues studied by the Minnesota Higher Education Coordinating Board, and reviews programs administered by the Board. Section 1 reviews enrollment trends and projections, student characteristics, and Minnesota's investment in…

A System for Evaluating Microcomputer Courseware for Vocational and Technical Education. Final Report.

ERIC Educational Resources Information Center

Chase, Shirley A.; And Others

A project was conducted to design a system for evaluating microcomputer courseware for vocational and technical education. Through a literature review and contacts with organizations and individuals involved in courseware evaluation and use, project staff identified and acquired for review documents pertaining to courseware evaulation, vocational…

Support Materials for the Software Technical Review Process

DTIC Science & Technology

1988-04-01

the Software Technical Review Process Softwar-e reviewing is a general term applied to techniques for the use of human hitellectual power to detect...more systematic than random. It utilizes data supplied by students, rather than relying solely on the subjective opinions of the instructor. The...The experience of other users is now essential.) "• Are the resulting grades accurate? (Thus far, they appear to correlate with student grades on

Advances in optimal routing through computer networks

NASA Technical Reports Server (NTRS)

Paz, I. M.

1977-01-01

The optimal routing problem is defined. Progress in solving the problem during the previous decade is reviewed, with special emphasis on technical developments made during the last few years. The relationships between the routing, the throughput, and the switching technology used are discussed and their future trends are reviewed. Economic aspects are also briefly considered. Modern technical approaches for handling the routing problems and, more generally, the flow control problems are reviewed.

32 CFR 518.21 - Collection of fees and fee rates for technical data.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Fee rates-(1) Costs for a manual search of technical data. Type Grade Hourly rate ($) Clerical E9/GS 8... costs for technical data. Type Cost ($) Aerial photograph, maps, specifications, permits, charts... microfilm indices, each .10 (e) Review time costs of technical data. Type Grade Hourly rate($) Clerical E9...

32 CFR 518.21 - Collection of fees and fee rates for technical data.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Fee rates-(1) Costs for a manual search of technical data. Type Grade Hourly rate ($) Clerical E9/GS 8... costs for technical data. Type Cost ($) Aerial photograph, maps, specifications, permits, charts... microfilm indices, each .10 (e) Review time costs of technical data. Type Grade Hourly rate($) Clerical E9...

32 CFR 518.21 - Collection of fees and fee rates for technical data.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Fee rates-(1) Costs for a manual search of technical data. Type Grade Hourly rate ($) Clerical E9/GS 8... costs for technical data. Type Cost ($) Aerial photograph, maps, specifications, permits, charts... microfilm indices, each .10 (e) Review time costs of technical data. Type Grade Hourly rate($) Clerical E9...

32 CFR 518.21 - Collection of fees and fee rates for technical data.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) Fee rates-(1) Costs for a manual search of technical data. Type Grade Hourly rate ($) Clerical E9/GS 8... costs for technical data. Type Cost ($) Aerial photograph, maps, specifications, permits, charts... microfilm indices, each .10 (e) Review time costs of technical data. Type Grade Hourly rate($) Clerical E9...

Announcement Notice (AN) 241.4 - Software | OSTI, US Dept of Energy Office

Science.gov Websites

of Scientific and Technical Information Skip to main content Scientific and Technical Information Program The home of the U.S. Department of Energy's Scientific and Technical Information Program ) Scientific and Technical Information (STI) products for announcement and availability. An AN includes review

Actions Needed to Ensure Scientific and Technical Information is Adequately Reviewed at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center

NASA Technical Reports Server (NTRS)

2008-01-01

This audit was initiated in response to a hotline complaint regarding the review, approval, and release of scientific and technical information (STI) at Johnson Space Center. The complainant alleged that Johnson personnel conducting export control reviews of STI were not fully qualified to conduct those reviews and that the reviews often did not occur until after the STI had been publicly released. NASA guidance requires that STI, defined as the results of basic and applied scientific, technical, and related engineering research and development, undergo certain reviews prior to being released outside of NASA or to audiences that include foreign nationals. The process includes technical, national security, export control, copyright, and trade secret (e.g., proprietary data) reviews. The review process was designed to preclude the inappropriate dissemination of sensitive information while ensuring that NASA complies with a requirement of the National Aeronautics and Space Act of 1958 (the Space Act)1 to provide for the widest practicable and appropriate dissemination of information resulting from NASA research activities. We focused our audit on evaluating the STI review process: specifically, determining whether the roles and responsibilities for the review, approval, and release of STI were adequately defined and documented in NASA and Center-level guidance and whether that guidance was effectively implemented at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center. Johnson was included in the review because it was the source of the initial complaint, and Goddard, Langley, and Marshall were included because those Centers consistently produce significant amounts of STI.

Low Rates of Major Complications for Radiofrequency Ablation of Atrial Fibrillation Maintained Over 14 Years: A Single Centre Experience of 2750 Consecutive Cases.

PubMed

Voskoboinik, Aleksandr; Sparks, Paul B; Morton, Joseph B; Lee, Geoffrey; Joseph, Stephen A; Hawson, Joshua J; Kistler, Peter M; Kalman, Jonathan M

2018-02-03

Despite technological advances, studies continue to report high complication rates for atrial fibrillation (AF) ablation. We sought to review complication rates for AF ablation at a high-volume centre over a 14-year period and identify predictors of complications. We reviewed prospectively collected data from 2750 consecutive AF ablation procedures at our institution using radiofrequency energy (RF) between January 2004 and May 2017. All cases were performed under general anaesthetic with transoesophageal echocardiography (TEE), 3D-mapping and an irrigated ablation catheter. Double transseptal puncture was performed under TEE guidance. All patients underwent wide antral circumferential isolation of the pulmonary veins (30W anteriorly, 25W posteriorly) with substrate modification at operator discretion. Of 2255 initial and 495 redo procedures, ablation strategies were: pulmonary vein isolation (PVI) only 2097 (76.3%), PVI+lines 368 (13.4%), PVI+posterior wall 191 (6.9%), PVI+cavotricuspid isthmus 277 (10.1%). There were 23 major (0.84%) and 20 minor (0.73%) complications. Cardiac tamponade (five cases - 0.18%) and phrenic nerve palsy (one case - 0.04%) rates were very low. Major vascular complications necessitating surgery or blood transfusion occurred in five patients (0.18%). There were no cases of death, permanent disability, atrio-oesophageal fistulae or symptomatic pulmonary vein (PV) stenosis, although there were five TEE probe-related complications (0.18%). Female gender (OR 2.14; 95% CI 1.07-4.26) but not age >70 (OR 1.01) was the only multivariate predictor of complications. Atrial fibrillation ablation performed at a high-volume centre using RF can be achieved with a low major complication rate in a representative AF population over a sustained period of time. Copyright © 2018 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

The history of head transplantation: a review.

PubMed

Lamba, Nayan; Holsgrove, Daniel; Broekman, Marike L

2016-12-01

Since the turn of the last century, the prospect of head transplantation has captured the imagination of scientists and the general public. Recently, head transplant has regained attention in popular media, as neurosurgeons have proposed performing this procedure in 2017. Given the potential impact of such a procedure, we were interested in learning the history of the technical hurdles that need to be overcome, and determine if it is even technically possible to perform such a procedure on humans today. We conducted a historical review of available literature on the technical challenges and developments of head transplantation. The many social, psychological, ethical, religious, cultural, and legal questions of head transplantation were beyond the scope of this review. Our historical review identified the following important technical considerations related to performing a head transplant: maintenance of blood flow to an isolated brain via vessel anastomosis; availability of immunosuppressive agents; spinal anastomosis and fusion following cord transfection; pain control in the recipient. Several animal studies have demonstrated success in maintaining recipient cerebral perfusion and achieving immunosuppression. However, there is currently sparse evidence in favor of successful spinal anastomosis and fusion after transection. While recent publications by an Italian group offer novel approaches to this challenge, research on this topic has been sparse and hinges on procedures performed in animal models in the 1970s. How transferrable these older methods are to the human nervous system is unclear and warrants further exploration. Our review identified several important considerations related to performing a viable head transplantation. Besides the technical challenges that remain, there are important ethical issues to consider, such as exploitation of vulnerable patients and informed consent. Thus, besides the remaining technical challenges, these ethical issues will also need to be addressed before moving these studies to the clinic.

48 CFR 801.602-80 - Legal and technical review-Office of Construction and Facilities Management and National Cemetery...

Code of Federal Regulations, 2012 CFR

2012-10-01

...-Office of Construction and Facilities Management and National Cemetery Administration. 801.602-80 Section... Responsibilities 801.602-80 Legal and technical review-Office of Construction and Facilities Management and National Cemetery Administration. An Office of Construction and Facilities Management or National Cemetery...

48 CFR 801.602-80 - Legal and technical review-Office of Construction and Facilities Management and National Cemetery...

Code of Federal Regulations, 2011 CFR

2011-10-01

...-Office of Construction and Facilities Management and National Cemetery Administration. 801.602-80 Section... Responsibilities 801.602-80 Legal and technical review-Office of Construction and Facilities Management and National Cemetery Administration. An Office of Construction and Facilities Management or National Cemetery...

48 CFR 801.602-80 - Legal and technical review-Office of Construction and Facilities Management and National Cemetery...

Code of Federal Regulations, 2013 CFR

2013-10-01

...-Office of Construction and Facilities Management and National Cemetery Administration. 801.602-80 Section... Responsibilities 801.602-80 Legal and technical review-Office of Construction and Facilities Management and National Cemetery Administration. An Office of Construction and Facilities Management or National Cemetery...

48 CFR 801.602-80 - Legal and technical review-Office of Construction and Facilities Management and National Cemetery...

Code of Federal Regulations, 2014 CFR

2014-10-01

...-Office of Construction and Facilities Management and National Cemetery Administration. 801.602-80 Section... Responsibilities 801.602-80 Legal and technical review-Office of Construction and Facilities Management and National Cemetery Administration. An Office of Construction and Facilities Management or National Cemetery...

48 CFR 801.602-78 - Processing solicitations and contract documents for legal or technical review-Veterans Health...

Code of Federal Regulations, 2013 CFR

2013-10-01

..., Central Office (except Office of Construction and Facilities Management), the National Acquisition Center, and the Denver Acquisition and Logistics Center. 801.602-78 Section 801.602-78 Federal Acquisition... Acquisition Center, and the Denver Acquisition and Logistics Center. (a) If legal or technical review is...

48 CFR 801.602-78 - Processing solicitations and contract documents for legal or technical review-Veterans Health...

Code of Federal Regulations, 2014 CFR

2014-10-01

..., Central Office (except Office of Construction and Facilities Management), the National Acquisition Center, and the Denver Acquisition and Logistics Center. 801.602-78 Section 801.602-78 Federal Acquisition... Acquisition Center, and the Denver Acquisition and Logistics Center. (a) If legal or technical review is...

48 CFR 801.602-78 - Processing solicitations and contract documents for legal or technical review-Veterans Health...

Code of Federal Regulations, 2012 CFR

2012-10-01

..., Central Office (except Office of Construction and Facilities Management), the National Acquisition Center, and the Denver Acquisition and Logistics Center. 801.602-78 Section 801.602-78 Federal Acquisition... Acquisition Center, and the Denver Acquisition and Logistics Center. (a) If legal or technical review is...

48 CFR 801.602-77 - Processing solicitations and contract documents for legal or technical review-general.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Processing solicitations and contract documents for legal or technical review-general. 801.602-77 Section 801.602-77 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS...

10 CFR 1304.101 - Purpose and scope.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Purpose and scope. 1304.101 Section 1304.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.101 Purpose and scope. This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding...

10 CFR 1304.101 - Purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Purpose and scope. 1304.101 Section 1304.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.101 Purpose and scope. This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding...

10 CFR 1304.101 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Purpose and scope. 1304.101 Section 1304.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.101 Purpose and scope. This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding...

10 CFR 1304.105 - Requests for access to records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Requests for access to records. 1304.105 Section 1304.105 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.105 Requests for access to records.... Nuclear Waste Technical Review Board; 2300 Clarendon Blvd., Suite 1300; Arlington, VA 22201. (c) Requests...

10 CFR 1304.105 - Requests for access to records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Requests for access to records. 1304.105 Section 1304.105 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.105 Requests for access to records.... Nuclear Waste Technical Review Board; 2300 Clarendon Blvd., Suite 1300; Arlington, VA 22201. (c) Requests...

10 CFR 1304.101 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Purpose and scope. 1304.101 Section 1304.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.101 Purpose and scope. This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding...

10 CFR 1304.105 - Requests for access to records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Requests for access to records. 1304.105 Section 1304.105 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.105 Requests for access to records.... Nuclear Waste Technical Review Board; 2300 Clarendon Blvd., Suite 1300; Arlington, VA 22201. (c) Requests...

10 CFR 1304.105 - Requests for access to records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Requests for access to records. 1304.105 Section 1304.105 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.105 Requests for access to records.... Nuclear Waste Technical Review Board; 2300 Clarendon Blvd., Suite 1300; Arlington, VA 22201. (c) Requests...

10 CFR 1304.101 - Purpose and scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Purpose and scope. 1304.101 Section 1304.101 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.101 Purpose and scope. This part sets forth the policies and procedures of the U.S. Nuclear Waste Technical Review Board (Board) regarding...

General Circulation Model Output for Forest Climate Change Research and Applications

Treesearch

Ellen J. Cooter; Brian K. Eder; Sharon K. LeDuc; Lawrence Truppi

1993-01-01

This report reviews technical aspects of and summarizes output from four climate models. Recommendations concerning the use of these outputs in forest impact assessments are made. This report reviews technical aspects of and summarizes output from four climate models. Recommendations concerning the use of these outputs in forest impact assessments are made.

10 CFR 1304.103 - Privacy Act inquiries.

Code of Federal Regulations, 2010 CFR

2010-01-01

... writing may be sent to: Privacy Act Officer, U.S. Nuclear Waste Technical Review Board, 2300 Clarendon... NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.103 Privacy Act inquiries. (a) Requests... contains a record pertaining to him or her may file a request in person or in writing, via the internet, or...

10 CFR 1304.108 - Appealing denials of access.

Code of Federal Regulations, 2010 CFR

2010-01-01

... writing. The appeal should be directed to Executive Director; U.S. Technical Review Board; 2300 Clarendon... 10 Energy 4 2010-01-01 2010-01-01 false Appealing denials of access. 1304.108 Section 1304.108 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.108 Appealing denials of access...

76 FR 10044 - Notice of Proposed Information Collection for Public Comment Public Housing Assessment System...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-23

... Database Adjustments AGENCY: Office of the Assistant Secretary for Public and Indian Housing, HUD. ACTION...: Public Housing Assessment System Appeals, Technical Reviews and Database Adjustments. OMB Control Number..., at Sec. 902.24, a database adjustment if certain conditions are present. A technical review of the...

Technical Processing Librarians in the 1980's: Current Trends and Future Forecasts.

ERIC Educational Resources Information Center

Kennedy, Gail

1980-01-01

This review of recent and anticipated advances in library automation technology and methodology includes a review of the effects of OCLC, MARC formatting, AACR2, and increasing costs, as well as predictions of the impact on library technical processing of networking, expansion of automation, minicomputers, specialized reference services, and…

Development of an Updated Strategic Marketing Plan for Fox Valley Technical College.

ERIC Educational Resources Information Center

May, Susan A.

This project was conducted to develop a comprehensive strategic marketing plan for Fox Valley Technical College (FVTC). Components included a review of the literature, establishing criteria for the plan, validation of the criteria, the actual development of the plan involving a formative committee, and the review of institutional marketing plans…

10 CFR 1304.109 - Requests for correction of records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Requests for correction of records. 1304.109 Section 1304.109 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.109 Requests for correction... Act Officer; U.S. Nuclear Waste Technical Review Board; 2300 Clarendon Blvd., Suite 1300; Arlington...

10 CFR 1304.109 - Requests for correction of records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Requests for correction of records. 1304.109 Section 1304.109 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.109 Requests for correction... Act Officer; U.S. Nuclear Waste Technical Review Board; 2300 Clarendon Blvd., Suite 1300; Arlington...

10 CFR 1304.109 - Requests for correction of records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Requests for correction of records. 1304.109 Section 1304.109 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.109 Requests for correction... Act Officer; U.S. Nuclear Waste Technical Review Board; 2300 Clarendon Blvd., Suite 1300; Arlington...

10 CFR 1304.109 - Requests for correction of records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Requests for correction of records. 1304.109 Section 1304.109 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.109 Requests for correction... Act Officer; U.S. Nuclear Waste Technical Review Board; 2300 Clarendon Blvd., Suite 1300; Arlington...

10 CFR 1304.109 - Requests for correction of records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Requests for correction of records. 1304.109 Section 1304.109 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.109 Requests for correction... Act Officer; U.S. Nuclear Waste Technical Review Board; 2300 Clarendon Blvd., Suite 1300; Arlington...

A Critical Review of the Technical Characteristics of Current Preschool Screening Batteries

ERIC Educational Resources Information Center

Emmons, Michael R.; Alfonso, Vincent C.

2005-01-01

The current review provides a summary and evaluation of the technical characteristics of five preschool screening batteries, including the Brigance Screens, DIAL-3, ESI-R, ESP, and FirstSTEP. These norm-referenced instruments were selected on the basis of their commercial availability, description as a screening instrument, and ability to assess…

Measuring the Value Added by Technical Documentation: A Review of Research and Practice.

ERIC Educational Resources Information Center

Mead, Jay

1998-01-01

Reviews existing work on establishing value of technical documentation to determine its principles. States that value can be returned by reducing internal investment, increasing sales, and reducing after-sales costs. Argues that further research will improve the understanding of information as the product itself, rather than simply a supporting…

Peer Review of a Formal Verification/Design Proof Methodology

NASA Technical Reports Server (NTRS)

1983-01-01

The role of formal verification techniques in system validation was examined. The value and the state of the art of performance proving for fault-tolerant compuers were assessed. The investigation, development, and evaluation of performance proving tools were reviewed. The technical issues related to proof methodologies are examined. The technical issues discussed are summarized.

Improvements in State and Local Planning for Mass Dispensing of Medical Countermeasures: The Technical Assistance Review Program, United States, 2007-2014.

PubMed

Renard, Paul G; Vagi, Sara J; Reinold, Chris M; Silverman, Brenda L; Avchen, Rachel N

2017-09-01

To evaluate and describe outcomes of state and local medical countermeasure preparedness planning, which is critical to ensure rapid distribution and dispensing of a broad spectrum of life-saving medical assets during a public health emergency. We used 2007 to 2014 state and local data collected from the Centers for Disease Control and Prevention's Technical Assistance Review. We calculated descriptive statistics from 50 states and 72 local Cities Readiness Initiative jurisdictions that participated in the Technical Assistance Review annually. From 2007 to 2014, the average overall Technical Assistance Review score increased by 13% for states and 41% for Cities Readiness Initiative jurisdictions. In 2014, nearly half of states achieved the maximum possible overall score (100), and 94% of local Cities Readiness Initiative jurisdictions achieved a score of 90 or more. Despite challenges, effective and timely medical countermeasure distribution and dispensing is possible with appropriate planning, staff, and resources. However, vigilance in training, exercising, and improving plans from lessons learned in a sustained, coordinated way is critical to ensure continued public health preparedness success.

Effective Synthesis of Sulfate Metabolites of Chlorinated Phenols

PubMed Central

Lehmler, Hans-Joachim; He, Xianran; Li, Xueshu; Duffel, Michael W.; Parkin, Sean

2013-01-01

Chlorophenols are an important class of persistent environmental contaminants and have been implicated in a range of adverse health effects, including cancer. They are readily conjugated and excreted as the corresponding glucuronides and sulfates in the urine of humans and other species. Here we report the synthesis and characterization of a series of ten chlorophenol sulfates by sulfation of the corresponding chlorophenols with 2,2,2-trichloroethyl (TCE) chlorosulfate using N,N-dimethylaminopyridine (DMAP) as base. Deprotection of the chlorophenol diesters with zinc powder/ammonium formate yielded the respective chlorophenol sulfate ammonium salts in good yield. The molecular structure of three TCE-protected chlorophenol sulfate diesters and one chlorophenol sulfate monoester were confirmed by X-ray crystal structure analysis. The chlorophenol sulfates were stable for several months if stored at −20 °C and, thus, are useful for future toxicological, environmental and human biomonitoring studies. PMID:23906814

Piezoelectric Actuator Modeling Using MSC/NASTRAN and MATLAB

NASA Technical Reports Server (NTRS)

Reaves, Mercedes C.; Horta, Lucas G.

2003-01-01

This paper presents a procedure for modeling structures containing piezoelectric actuators using MSCMASTRAN and MATLAB. The paper describes the utility and functionality of one set of validated modeling tools. The tools described herein use MSCMASTRAN to model the structure with piezoelectric actuators and a thermally induced strain to model straining of the actuators due to an applied voltage field. MATLAB scripts are used to assemble the dynamic equations and to generate frequency response functions. The application of these tools is discussed using a cantilever aluminum beam with a surface mounted piezoelectric actuator as a sample problem. Software in the form of MSCINASTRAN DMAP input commands, MATLAB scripts, and a step-by-step procedure to solve the example problem are provided. Analysis results are generated in terms of frequency response functions from deflection and strain data as a function of input voltage to the actuator.

Modeling epidemics on adaptively evolving networks: A data-mining perspective.

PubMed

Kattis, Assimakis A; Holiday, Alexander; Stoica, Ana-Andreea; Kevrekidis, Ioannis G

2016-01-01

The exploration of epidemic dynamics on dynamically evolving ("adaptive") networks poses nontrivial challenges to the modeler, such as the determination of a small number of informative statistics of the detailed network state (that is, a few "good observables") that usefully summarize the overall (macroscopic, systems-level) behavior. Obtaining reduced, small size accurate models in terms of these few statistical observables--that is, trying to coarse-grain the full network epidemic model to a small but useful macroscopic one--is even more daunting. Here we describe a data-based approach to solving the first challenge: the detection of a few informative collective observables of the detailed epidemic dynamics. This is accomplished through Diffusion Maps (DMAPS), a recently developed data-mining technique. We illustrate the approach through simulations of a simple mathematical model of epidemics on a network: a model known to exhibit complex temporal dynamics. We discuss potential extensions of the approach, as well as possible shortcomings.

The NASTRAN User's Manual Level 16.0 and Supplement

NASA Technical Reports Server (NTRS)

1976-01-01

The user's manual is restricted to those items related to the use of NASTRAN that are independent of the computing system being used. The features of NASTRAN described include: (1) procedures for defining and loading a structural model and a functional reference for every card that is used for structural modeling; (2) the NASTRAN data deck, including the details for each of the data cards; (3) the NASTRAN control cards that are associated with the use of the program; (4) rigid format procedures, along with specific instructions for the use of each rigid format: (5) procedures for using instructions for the use of each rigid format; (5) procedures for using the NASTRAN plotting capability; (6) procedures governing the creation of DMAP programs; and (7) the NASTRAN diagnostic messages. The NASTRAN dictionary of mnemonics, acronyms, phrases, and other commonly used NASTRAN terms is included along with a limited number of sample problems.

Experiences with the use of axisymmetric elements in cosmic NASTRAN for static analysis

NASA Technical Reports Server (NTRS)

Cooper, Michael J.; Walton, William C.

1991-01-01

Discussed here are some recent finite element modeling experiences using the axisymmetric elements CONEAX, TRAPAX, and TRIAAX, from the COSMIC NASTRAN element library. These experiences were gained in the practical application of these elements to the static analysis of helicopter rotor force measuring systems for two design projects for the NASA Ames Research Center. These design projects were the Rotor Test Apparatus and the Large Rotor Test Apparatus, which are dedicated to basic helicopter research. Here, a genetic axisymmetric model is generated for illustrative purposes. Modeling considerations are discussed, and the advantages and disadvantages of using axisymmetric elements are presented. Asymmetric mechanical and thermal loads are applied to the structure, and single and multi-point constraints are addressed. An example that couples the axisymmetric model to a non-axisymmtric model is demonstrated, complete with DMAP alters. Recommendations for improving the elements and making them easier to use are offered.

In vivo quantification of amyloid burden in TTR-related cardiac amyloidosis

PubMed Central

Kollikowski, Alexander Marco; Kahles, Florian; Kintsler, Svetlana; Hamada, Sandra; Reith, Sebastian; Knüchel, Ruth; Röcken, Christoph; Mottaghy, Felix Manuel; Marx, Nikolaus; Burgmaier, Mathias

2017-01-01

Summary Cardiac transthyretin-related (ATTR) amyloidosis is a severe cardiomyopathy for which therapeutic approaches are currently under development. Because non-invasive imaging techniques such as cardiac magnetic resonance imaging and echocardiography are non-specific, the diagnosis of ATTR amyloidosis is still based on myocardial biopsy. Thus, diagnosis of ATTR amyloidosis is difficult in patients refusing myocardial biopsy. Furthermore, myocardial biopsy does not allow 3D-mapping and quantification of myocardial ATTR amyloid. In this report we describe a 99mTc-DPD-based molecular imaging technique for non-invasive single-step diagnosis, three-dimensional mapping and semiquantification of cardiac ATTR amyloidosis in a patient with suspected amyloid heart disease who initially rejected myocardial biopsy. This report underlines the clinical value of SPECT-based nuclear medicine imaging to enable non-invasive diagnosis of cardiac ATTR amyloidosis, particularly in patients rejecting biopsy. PMID:29259858

Implementation of the block-Krylov boundary flexibility method of component synthesis

NASA Technical Reports Server (NTRS)

Carney, Kelly S.; Abdallah, Ayman A.; Hucklebridge, Arthur A.

1993-01-01

A method of dynamic substructuring is presented which utilizes a set of static Ritz vectors as a replacement for normal eigenvectors in component mode synthesis. This set of Ritz vectors is generated in a recurrence relationship, which has the form of a block-Krylov subspace. The initial seed to the recurrence algorithm is based on the boundary flexibility vectors of the component. This algorithm is not load-dependent, is applicable to both fixed and free-interface boundary components, and results in a general component model appropriate for any type of dynamic analysis. This methodology was implemented in the MSC/NASTRAN normal modes solution sequence using DMAP. The accuracy is found to be comparable to that of component synthesis based upon normal modes. The block-Krylov recurrence algorithm is a series of static solutions and so requires significantly less computation than solving the normal eigenspace problem.

A general low frequency acoustic radiation capability for NASTRAN

NASA Technical Reports Server (NTRS)

Everstine, G. C.; Henderson, F. M.; Schroeder, E. A.; Lipman, R. R.

1986-01-01

A new capability called NASHUA is described for calculating the radiated acoustic sound pressure field exterior to a harmonically-excited arbitrary submerged 3-D elastic structure. The surface fluid pressures and velocities are first calculated by coupling a NASTRAN finite element model of the structure with a discretized form of the Helmholtz surface integral equation for the exterior fluid. After the fluid impedance is calculated, most of the required matrix operations are performed using the general matrix manipulation package (DMAP) available in NASTRAN. Far field radiated pressures are then calculated from the surface solution using the Helmholtz exterior integral equation. Other output quantities include the maximum sound pressure levels in each of the three coordinate planes, the rms and average surface pressures and normal velocities, the total radiated power and the radiation efficiency. The overall approach is illustrated and validated using known analytic solutions for submerged spherical shells subjected to both uniform and nonuniform applied loads.

NASTRAN multipartitioning and one-shot substructuring

NASA Technical Reports Server (NTRS)

Levy, A.

1973-01-01

For intermediate size problems where all the data is accessible, the present method of substructuring in three separate phases (for static analysis) is unneccessarily cumbersome. The versatility of NASTRAN's DMAP and internal logic lends itself to finding a practical alternative to these procedures whereby self-contained special-purpose ALTER packages can be written to be run in one pass. Two examples are presented here under the titles of multipartitioning and one-shot substructuring. The flow of multipartitioning resembles that of the present three-phase substructuring. The basic effect is to partition the structure into substructures and operate on each substructure separately. This can be used to reduce the bandwidth of a given problem as well as to store information which will allow a change to be made in one of the substructures in a later run. This latter procedure is carried out in a second program titled one-shot substructuring.

Design and Concept of Polyzwitterionic Copolymer Microgel Drug Delivery Systems In Situ Loaded with Non-steroidal Anti-inflammatory Ibuprofen.

PubMed

Kostova, Bistra; Kamenska, Elena; Georgieva, Dilyana; Balashev, Konstantin; Rachev, Dimitar; Georgiev, George

2017-01-01

Nowadays, the modern pharmaceutical investigations are directed toward obtaining of new polymer micro- and nano-sized drug delivery carriers. In this respect, the use of hydrogel carriers based on polyzwitterions (PZIs) is an opportunity in the preparation of polymer drug delivery systems with desired characteristics. This paper describes the synthesis and characterization of micro-structured p(VA-co-DMAPS) systems with different compositions in situ loaded with Ibuprofen by emulsifier-free emulsion copolymerization (EEC) in water. The mean size of the prepared microparticles was measured by SEM and particles have been visualized by AFM. The inclusion of Ibuprofen in the polyzwitterionic copolymer microgel systems was established by using DSC. In vitro drug release experiments were carried out in order to estimate the ability of the obtained microgels to modify the release of water-insoluble Ibuprofen.

Improved Equivalent Linearization Implementations Using Nonlinear Stiffness Evaluation

NASA Technical Reports Server (NTRS)

Rizzi, Stephen A.; Muravyov, Alexander A.

2001-01-01

This report documents two new implementations of equivalent linearization for solving geometrically nonlinear random vibration problems of complicated structures. The implementations are given the acronym ELSTEP, for "Equivalent Linearization using a STiffness Evaluation Procedure." Both implementations of ELSTEP are fundamentally the same in that they use a novel nonlinear stiffness evaluation procedure to numerically compute otherwise inaccessible nonlinear stiffness terms from commercial finite element programs. The commercial finite element program MSC/NASTRAN (NASTRAN) was chosen as the core of ELSTEP. The FORTRAN implementation calculates the nonlinear stiffness terms and performs the equivalent linearization analysis outside of NASTRAN. The Direct Matrix Abstraction Program (DMAP) implementation performs these operations within NASTRAN. Both provide nearly identical results. Within each implementation, two error minimization approaches for the equivalent linearization procedure are available - force and strain energy error minimization. Sample results for a simply supported rectangular plate are included to illustrate the analysis procedure.

A Case Study on the Status of Technical and Vocational Education in Thailand. Case Studies on Technical and Vocational Education in Asia and the Pacific.

ERIC Educational Resources Information Center

Shoolap, Charoon; Choomnoom, Siripan

This two-part report presents an overview of the vocational and technical education system in Thailand. The first part is a review of the current and likely future situations pertaining to vocational and technical education in that country. An analysis of economic conditions, human resource development, and the existing technical and vocational…

Technical cooperation on nuclear security between the United States and China : review of the past and opportunities for the future.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pregenzer, Arian Leigh

2011-12-01

The United States and China are committed to cooperation to address the challenges of the next century. Technical cooperation, building on a long tradition of technical exchange between the two countries, can play an important role. This paper focuses on technical cooperation between the United States and China in the areas of nonproliferation, arms control and other nuclear security topics. It reviews cooperation during the 1990s on nonproliferation and arms control under the U.S.-China Arms Control Exchange, discusses examples of ongoing activities under the Peaceful Uses of Technology Agreement to enhance security of nuclear and radiological material, and suggests opportunitiesmore » for expanding technical cooperation between the defense nuclear laboratories of both countries to address a broader range of nuclear security topics.« less

A Review of Legal Decisions Relevant to Technical Standards Used in Pharmacy School Admissions

PubMed Central

2017-01-01

The implementation of an effective and legally sound technical standards procedure for pharmacy schools requires a proactive approach by admissions officers. Applicants with disabilities are accorded significant rights that must not be infringed during the admissions process in order to ensure compliance with applicable law. This article provides a review of applicable state cases, federal cases, and OCR decisions and guidance to help pharmacy schools identify procedures and implement technical standards into their admissions processes as required by ACPE Standards 2016. PMID:28381897

Index to Nuclear Safety. A technical progress review by chronology, permuted title, and author. Vol. 11, No. 1--Vol. 17, No. 6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cottrell, W.B.; Klein, A.

1977-02-23

This index to Nuclear Safety covers articles in Nuclear Safety Vol. 11, No. 1 (Jan.-Feb. 1970), through Vol. 17, No. 6 (Nov.-Dec. 1976). The index includes a chronological list of articles (including abstract) followed by KWIC and Author Indexes. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. The index lists over 350 technical articles in the last six years of publication.

75 FR 33682 - Export Administration Regulations; Technical Amendments

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-15

...-01] RIN 0694-AE93 Export Administration Regulations; Technical Amendments AGENCY: Bureau of Industry... Bureau of Industry and Security (BIS) makes a technical amendment to the Export Administration... review of final decisions and orders issued in BIS export control administrative enforcement proceedings...

Boiling eXperiment Facility (BXF) Fluid Toxicity Technical Interchange Meeting (TIM) with the Payload Safety Review Panel (PSRP)

NASA Technical Reports Server (NTRS)

Sheredy, William A.

2012-01-01

A Technical Interchange meeting was held between the payload developers for the Boiling eXperiment Facility (BXF) and the NASA Safety Review Panel concerning operational anomaly that resulted in overheating one of the fluid heaters, shorted a 24VDC power supply and generated Perfluoroisobutylene (PFiB) from Perfluorohexane.

A Plan of Organization, Administration, and Elements of Finance for Vocational-Technical Adult Education, Birmingham City School System.

ERIC Educational Resources Information Center

Shelton, John Alton

Designed to help formulate a plan of organization and administration for vocational and technical education and adult education in the Birmingham, Alabama, city schools, this study entailed an extensive literature review on vocational education and administrative matters; a historical review of several Birmingham schools (Paul Hayne School,…

76 FR 50171 - Notice of Proposed Change to Section IV of the Virginia State Technical Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-12

... the Virginia NRCS State Technical Guide for review and comment. SUMMARY: It has been determined by the... Management No Till/Strip Till/Direct Seed, 344, Residue Management, Seasonal, 345, Residue and Tillage... public review and comment. For the next 30 days, the NRCS in Virginia will receive comments relative to...

76 FR 52634 - Notice of Proposed Change to Section IV of the Virginia State Technical Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-23

... NRCS State Technical Guide for review and comment. SUMMARY: It has been determined by the NRCS State... Management No Till/Strip Till/Direct Seed, 344, Residue Management, Seasonal, 345, Residue and Tillage... review and comment. For the next 30 days, the NRCS in Virginia will receive comments relative to the...

76 FR 53125 - Draft Toxicological Review of Libby Amphibole Asbestos: In Support of the Summary Information on...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-25

... is to allow all interested parties to present scientific and technical comments on draft IRIS health... and technical comments that will be provided to the Agency by the listening session participants. The... peer reviewers, they should also submit written comments during the public comment period using the...

Case Study of 'Engineering Peer Meetings' in JPL's ST-6 Project

NASA Technical Reports Server (NTRS)

Chao, Lawrence P.; Tumer, Irem

2004-01-01

This design process error-proofing case study describes a design review practice implemented by a project manager at NASA Jet Propulsion Laboratory. There are many types of reviews at NASA: required and not, formalized and informal, programmatic and technical. Standing project formal reviews such as the Preliminary Design Review (PDR) and Critical Design Review (CDR) are a required part of every project and mission development. However, the engineering peer reviews that support teams technical work on such projects are often informal, ad hoc, and inconsistent across the organization. This case study discusses issues and innovations identified by a project manager at JPL and implemented in 'engineering peer meetings' for his group.

Case Study of "Engineering Peer Meetings" in JPL's ST-6 Project

NASA Technical Reports Server (NTRS)

Tumer, Irem Y.; Chao, Lawrence P.

2003-01-01

This design process error-proofing case study describes a design review practice implemented by a project manager at NASA Jet Propulsion Laboratory. There are many types of reviews at NASA: required and not, formalized and informal, programmatic and technical. Standing project formal reviews such as the Preliminary Design Review (PDR) and Critical Design Review (CDR) are a required part of every project and mission development. However, the engineering peer reviews that support teams technical work on such projects are often informal, ad hoc, and inconsistent across the organization. This case study discusses issues and innovations identified by a project manager at JPL and implemented in "engineering peer meetings" for his group.

The impact of nontechnical skills on technical performance in surgery: a systematic review.

PubMed

Hull, Louise; Arora, Sonal; Aggarwal, Rajesh; Darzi, Ara; Vincent, Charles; Sevdalis, Nick

2012-02-01

Failures in nontechnical and teamwork skills frequently lie at the heart of harm and near-misses in the operating room (OR). The purpose of this systematic review was to assess the impact of nontechnical skills on technical performance in surgery. MEDLINE, EMBASE, PsycINFO databases were searched, and 2,041 articles were identified. After limits were applied, 341 articles were retrieved for evaluation. Of these, 28 articles were accepted for this review. Data were extracted from the articles regarding sample population, study design and setting, measures of nontechnical skills and technical performance, study findings, and limitations. Of the 28 articles that met inclusion criteria, 21 articles assessed the impact of surgeons' nontechnical skills on their technical performance. The evidence suggests that receiving feedback and effectively coping with stressful events in the OR has a beneficial impact on certain aspects of technical performance. Conversely, increased levels of fatigue are associated with detriments to surgical skill. One article assessed the impact of anesthesiologists' nontechnical skills on anesthetic technical performance, finding a strong positive correlation between the 2 skill sets. Finally, 6 articles assessed the impact of multiple nontechnical skills of the entire OR team on surgical performance. A strong relationship between teamwork failure and technical error was empirically demonstrated in these studies. Evidence suggests that certain nontechnical aspects of performance can enhance or, if lacking, contribute to deterioration of surgeons' technical performance. The precise extent of this effect remains to be elucidated. Copyright © 2012 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Independent technical review, handbook

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Purpose Provide an independent engineering review of the major projects being funded by the Department of Energy, Office of Environmental Restoration and Waste Management. The independent engineering review will address questions of whether the engineering practice is sufficiently developed to a point where a major project can be executed without significant technical problems. The independent review will focus on questions related to: (1) Adequacy of development of the technical base of understanding; (2) Status of development and availability of technology among the various alternatives; (3) Status and availability of the industrial infrastructure to support project design, equipment fabrication, facility construction,more » and process and program/project operation; (4) Adequacy of the design effort to provide a sound foundation to support execution of project; (5) Ability of the organization to fully integrate the system, and direct, manage, and control the execution of a complex major project.« less

The Unfortunate Human Factor: A Selective History of Human Factors for Technical Communicators.

ERIC Educational Resources Information Center

Johnson, Robert R.

1994-01-01

Reviews moments in the history of human factors that are especially relevant to the field of technical communications. Discusses human factors research that is applicable to technical communications. Focuses on qualitative usability research, minimalism, and human activity interface design. (HB)

75 FR 13209 - Proposed Information Collection (Technical Industry Standards) Activity: Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-18

... (Technical Industry Standards) Activity: Comment Request AGENCY: Office of Acquisition and Logistics... Industry Standards. OMB Control Number: 2900-0586. Type of Review: Extension of a currently approved collection. Abstract: VAAR provision 852.211-75, Technical Industry Standards, requires items offered for...

1998 NASA High-Speed Research Program Aerodynamic Performance Workshop. Volume 1; Configuration Aerodynamics

NASA Technical Reports Server (NTRS)

McMillin, S. Naomi (Editor)

1999-01-01

NASA's High-Speed Research Program sponsored the 1998 Aerodynamic Performance Technical Review on February 9-13, in Los Angeles, California. The review was designed to bring together NASA and industry HighSpeed Civil Transport (HSCT) Aerodynamic Performance technology development participants in areas of. Configuration Aerodynamics (transonic and supersonic cruise drag prediction and minimization), High-Lift, and Flight Controls. The review objectives were to: (1) report the progress and status of HSCT aerodynamic performance technology development; (2) disseminate this technology within the appropriate technical communities; and (3) promote synergy among the scientists and engineers working HSCT aerodynamics. In particular, single and multi-point optimized HSCT configurations, HSCT high-lift system performance predictions, and HSCT simulation results were presented along with executive summaries for all the Aerodynamic Performance technology areas. The HSR Aerodynamic Performance Technical Review was held simultaneously with the annual review of the following airframe technology areas: Materials and Structures, Environmental Impact, Flight Deck, and Technology Integration. Thus, a fourth objective of the Review was to promote synergy between the Aerodynamic Performance technology area and the other technology areas of the HSR Program.

1998 NASA High-Speed Research Program Aerodynamic Performance Workshop. Volume 2; High Lift

NASA Technical Reports Server (NTRS)

McMillin, S. Naomi (Editor)

1999-01-01

NASA's High-Speed Research Program sponsored the 1998 Aerodynamic Performance Technical Review on February 9-13, in Los Angeles, California. The review was designed to bring together NASA and industry High-Speed Civil Transport (HSCT) Aerodynamic Performance technology development participants in areas of Configuration Aerodynamics (transonic and supersonic cruise drag prediction and minimization), High-Lift, and Flight Controls. The review objectives were to (1) report the progress and status of HSCT aerodynamic performance technology development; (2) disseminate this technology within the appropriate technical communities; and (3) promote synergy among the scientists and engineers working HSCT aerodynamics. In particular, single- and multi-point optimized HSCT configurations, HSCT high-lift system performance predictions, and HSCT simulation results were presented along with executive summaries for all the Aerodynamic Performance technology areas. The HSR Aerodynamic Performance Technical Review was held simultaneously with the annual review of the following airframe technology areas: Materials and Structures, Environmental Impact, Flight Deck, and Technology Integration. Thus, a fourth objective of the Review was to promote synergy between the Aerodynamic Performance technology area and the other technology areas of the HSR Program.

1998 NASA High-Speed Research Program Aerodynamic Performance Workshop. Volume 1; Configuration Aerodynamics

NASA Technical Reports Server (NTRS)

McMillin, S. Naomi (Editor)

1999-01-01

NASA's High-Speed Research Program sponsored the 1998 Aerodynamic Performance Technical Review on February 9-13, in Los Angeles, California. The review was designed to bring together NASA and industry High-Speed Civil Transport (HSCT) Aerodynamic Performance technology development participants in areas of Configuration Aerodynamics (transonic and supersonic cruise drag prediction and minimization), High-Lift, and Flight Controls. The review objectives were to (1) report the progress and status of HSCT aerodynamic performance technology development; (2) disseminate this technology within the appropriate technical communities; and (3) promote synergy among the scientists and engineers working HSCT aerodynamics. In particular, single and multi-point optimized HSCT configurations, HSCT high-lift system performance predictions, and HSCT simulation results were presented along with executive summaries for all the Aerodynamic Performance technology areas. The HSR Aerodynamic Performance Technical Review was held simultaneously with the annual review of the following airframe technology areas: Materials and Structures, Environmental Impact, Flight Deck, and Technology Integration. Thus, a fourth objective of the Review was to promote synergy between the Aerodynamic Performance technology area and the other technology areas of the HSR Program.

Burns education: The emerging role of simulation for training healthcare professionals.

PubMed

Sadideen, Hazim; Goutos, Ioannis; Kneebone, Roger

2017-02-01

Burns education appears to be under-represented in UK undergraduate curricula. However current postgraduate courses in burns education provide formal training in resuscitation and management. Simulation has proven to be a powerful modality to advance surgical training in both technical and non-technical skills. We present a literature review that summarises the format of current burns education, and provides detailed insight into historic, current and novel advances in burns simulation for both technical and non-technical skills, that can be used to augment surgical training. Addressing the economic and practical limitations of current immersive surgical simulation is important, and this review proposes future directions for integration of innovative simulation strategies into training curricula. Copyright © 2016 Elsevier Ltd and ISBI. All rights reserved.

76 FR 9607 - Notice of Proposed Information Collection for Technical Evaluation Surveys

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-18

... Information Collection for Technical Evaluation Surveys AGENCY: Office of Surface Mining Reclamation and... information collection request for its Technical Evaluation customer surveys has been forwarded to the Office of Management and Budget (OMB) for review and comment. The information collection request describes...

Effects of technical editing in biomedical journals: a systematic review.

PubMed

Wager, Elizabeth; Middleton, Philippa

2002-06-05

Technical editing supposedly improves the accuracy and clarity of journal articles. We examined evidence of its effects on research reports in biomedical journals. Subset of a systematic review using Cochrane methods, searching MEDLINE, EMBASE, and other databases from earliest entries to February 2000 by using inclusive search terms; hand searching relevant journals. We selected comparative studies of the effects of editorial processes on original research articles between acceptance and publication in biomedical journals. Two reviewers assessed each study and performed independent data extraction. The 11 studies on technical editing indicate that it improves the readability of articles slightly (as measured by Gunning Fog and Flesch reading ease scores), may improve other aspects of their quality, can increase the accuracy of references and quotations, and raises the quality of abstracts. Supplying authors with abstract preparation instructions had no discernible effect. Considering the time and resources devoted to technical editing, remarkably little is know about its effects or the effects of imposing different house styles. Studies performed at 3 journals employing relatively large numbers of professional technical editors suggest that their editorial processes are associated with increases in readability and quality of articles, but these findings may not be generalizable to other journals.

Using Model-Based Systems Engineering To Provide Artifacts for NASA Project Life-Cycle and Technical Reviews

NASA Technical Reports Server (NTRS)

Parrott, Edith L.; Weiland, Karen J.

2017-01-01

The ability of systems engineers to use model-based systems engineering (MBSE) to generate self-consistent, up-to-date systems engineering products for project life-cycle and technical reviews is an important aspect for the continued and accelerated acceptance of MBSE. Currently, many review products are generated using labor-intensive, error-prone approaches based on documents, spreadsheets, and chart sets; a promised benefit of MBSE is that users will experience reductions in inconsistencies and errors. This work examines features of SysML that can be used to generate systems engineering products. Model elements, relationships, tables, and diagrams are identified for a large number of the typical systems engineering artifacts. A SysML system model can contain and generate most systems engineering products to a significant extent and this paper provides a guide on how to use MBSE to generate products for project life-cycle and technical reviews. The use of MBSE can reduce the schedule impact usually experienced for review preparation, as in many cases the review products can be auto-generated directly from the system model. These approaches are useful to systems engineers, project managers, review board members, and other key project stakeholders.

Robotic Arm-Assisted Sonography: Review of Technical Developments and Potential Clinical Applications.

PubMed

Swerdlow, Daniel R; Cleary, Kevin; Wilson, Emmanuel; Azizi-Koutenaei, Bamshad; Monfaredi, Reza

2017-04-01

Ultrasound imaging requires trained personnel. Advances in robotics and data transmission create the possibility of telesonography. This review introduces clinicians to current technical work in and potential applications of this developing capability. Telesonography offers advantages in hazardous or remote environments. Robotically assisted ultrasound can reduce stress injuries in sonographers and has potential utility during robotic surgery and interventional procedures.

Reliability Abstracts and Technical Reviews January - December 1970. Volume 10, Nos. 1-12; R70-14805 - R70-15438

NASA Technical Reports Server (NTRS)

1970-01-01

Reliability Abstracts and Technical Reviews is an abstract and critical analysis service covering published and report literature on reliability. The service is designed to provide information on theory and practice of reliability as applied to aerospace and an objective appraisal of the quality, significance, and applicability of the literature abstracted.

Constructing a Validity Argument for the Objective Structured Assessment of Technical Skills (OSATS): A Systematic Review of Validity Evidence

ERIC Educational Resources Information Center

Hatala, Rose; Cook, David A.; Brydges, Ryan; Hawkins, Richard

2015-01-01

In order to construct and evaluate the validity argument for the Objective Structured Assessment of Technical Skills (OSATS), based on Kane's framework, we conducted a systematic review. We searched MEDLINE, EMBASE, CINAHL, PsycINFO, ERIC, Web of Science, Scopus, and selected reference lists through February 2013. Working in duplicate, we selected…

Vocational, Technical, and Practical Arts Education. Review of Educational Research, Volume 32, Number 4.

ERIC Educational Resources Information Center

American Educational Research Association, Washington, DC.

The major research findings for the 6-year period following October 1956 are reported in the categories: (1) Vocational, Technical, and Practical Arts Education which discusses the current status of research in vocational education and the practical arts and reviews significant research which cuts across or is relevant to two or more of the…

Improvements in State and Local Planning for Mass Dispensing of Medical Countermeasures: The Technical Assistance Review Program, United States, 2007–2014

PubMed Central

Vagi, Sara J.; Reinold, Chris M.; Silverman, Brenda L.; Avchen, Rachel N.

2017-01-01

Objectives. To evaluate and describe outcomes of state and local medical countermeasure preparedness planning, which is critical to ensure rapid distribution and dispensing of a broad spectrum of life-saving medical assets during a public health emergency. Methods. We used 2007 to 2014 state and local data collected from the Centers for Disease Control and Prevention’s Technical Assistance Review. We calculated descriptive statistics from 50 states and 72 local Cities Readiness Initiative jurisdictions that participated in the Technical Assistance Review annually. Results. From 2007 to 2014, the average overall Technical Assistance Review score increased by 13% for states and 41% for Cities Readiness Initiative jurisdictions. In 2014, nearly half of states achieved the maximum possible overall score (100), and 94% of local Cities Readiness Initiative jurisdictions achieved a score of 90 or more. Conclusions. Despite challenges, effective and timely medical countermeasure distribution and dispensing is possible with appropriate planning, staff, and resources. However, vigilance in training, exercising, and improving plans from lessons learned in a sustained, coordinated way is critical to ensure continued public health preparedness success. PMID:28892441

LBNL report of the vetting review of the GRETINA project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robinson, K.E.; Bercovitz, J.H.; Bieser, F.S.

GRETINA is a gamma-ray detector array capable of reconstructing the energy and spatial positions of gamma-ray interactions within the germanium crystals. It will be used to study the structure and stability of nuclei under various conditions. The new capabilities provided by gamma-ray tracking will give large gains in sensitivity for a large number of experiments, particularly those aimed at nuclei far from beta stability. A proposal for GRETINA was submitted to DOE in June 2003. It presented the scientific case, the readiness of technical development, the design, the suggested management organizations, and a proposed cost and schedule. The GRETINA proposalmore » received its CD0 approval in August 2003. The CD-1 review will be held on December 3 and 4, 2003, and will be handled by the DOE-N. This report presents the charge to the GRETINA vetting review committee, and the findings, comments and recommendations of this committee. The purpose of this project vetting review was to assure that the GRETINA project is on track to provide DOE and the nuclear physics community with the agreed upon deliverables within the agreed upon budget and schedule. The vetting review committee was asked to cover both technical and management aspects of the GRETINA Project. Reviewers offer expert knowledge in relevant areas and provide recommendations and findings to the project's management team. Upon successful completion, the Laboratory's Integrated Project Management Office (IPMO) will recommend signoff of the project to the Laboratory Directorate. The GRETINA vetting review committee was asked to consider all relevant aspects of the project's management, project execution plan (PEP), technical approach and status, cost estimate, resources, schedule and risk and, in doing so, to advise as to whether the GRETINA Project was likely to successfully provide the agreed upon deliverables within the agreed upon budget and schedule. The review committee was asked to identify any project areas that may be incomplete for the current phase in the project and any area of significant risk for the project reaching its objectives. The committee was also asked to review and evaluate the technical status of the project and advise on any concerns or significant technical risks.« less

Defense Technical Information Center (DTIC) - Its role in the USAF Scientific and Technical Information Program

NASA Technical Reports Server (NTRS)

Kuhn, Allan D.

1991-01-01

The Defense Technical Information Center (DTIC), the central repository for DOD scientific and technical information concerning studies and research and engineering efforts, is discussed. The present makeup of DTIC is described and its functions in producing technical reports and technical report bibliographies are examined. DTIC's outreach services are reviewed, as are its DTIC information and technology transfer programs. DTIC's plans for the year 2000 and its relation to the mission of the U.S. Air Force, including the Air Force's STINFO program, are addressed.

NASA Publications Guide for Authors. Revised

NASA Technical Reports Server (NTRS)

2005-01-01

This document presents guidelines for use by NASA authors for preparing and publishing their scientific and technical information (STI). Section 1 gives an overview. Section 2 describes each type of report in the NASA STI Report Series and other forms of publications. It also discusses dissemination and safeguarding of STI. Section 3 gives technical, data quality, and dissemination reviews, including the mandatory review via NASA Form 1676, NASA Scientific and Technical Information (STI) Document Availability Authorization (DAA). It also describes handling unlimited and limited/restricted STI. Section 4 provides recommended standards for document format, composition, and organization and element of a typical report. Section 5 presents miscellaneous preparation recommendations. Section 6 discusses two required forms, Standard Form 298 and NF-1676. The guide cites additional sources of information of standards, guidelines, and review and approval requirements.

In Pursuit of a Rewarding Career

ERIC Educational Resources Information Center

Murphy, Avon J.

2015-01-01

Avon Murphy has been a college professor, a technical communications program director, a government technical writer, a freelancer, a contract editor at Microsoft and other firms, and owner of Murphy Editing and Writing Services. An STC (Society for Technical Communication) Fellow, he was for 17 years book review editor for "Technical…

7 CFR 614.10 - Appeals before the Farm Service Agency county committee.

Code of Federal Regulations, 2010 CFR

2010-01-01

... section are completed, provide the FSA county committee with a written technical determination in the form... part 780, a participant may appeal a final technical determination or a program decision to the FSA... appeal requests review of the technical determination by the applicable State Conservationist prior to...

9 CFR 351.5 - Conditions of eligibility for certification service; review of applications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... technical animal fat, and a written description of the shipping, receiving, and inventory records maintained... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR...”); and such source materials will be rendered at the plant into technical animal fat eligible for export...

48 CFR 742.1170-4 - Progress reporting requirements and contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... progress. (b) Because the cognizant technical officer is the individual most familiar with the contractor's performance, the contractor must submit the progress reports directly to the cognizant technical officer. The cognizant technical officer must review the reports and advise the contracting officer, in writing, of any...

Technical editing of research reports in biomedical journals.

PubMed

Wager, Elizabeth; Middleton, Philippa

2008-10-08

Most journals try to improve their articles by technical editing processes such as proof-reading, editing to conform to 'house styles', grammatical conventions and checking accuracy of cited references. Despite the considerable resources devoted to technical editing, we do not know whether it improves the accessibility of biomedical research findings or the utility of articles. This is an update of a Cochrane methodology review first published in 2003. To assess the effects of technical editing on research reports in peer-reviewed biomedical journals, and to assess the level of accuracy of references to these reports. We searched The Cochrane Library Issue 2, 2007; MEDLINE (last searched July 2006); EMBASE (last searched June 2007) and checked relevant articles for further references. We also searched the Internet and contacted researchers and experts in the field. Prospective or retrospective comparative studies of technical editing processes applied to original research articles in biomedical journals, as well as studies of reference accuracy. Two review authors independently assessed each study against the selection criteria and assessed the methodological quality of each study. One review author extracted the data, and the second review author repeated this. We located 32 studies addressing technical editing and 66 surveys of reference accuracy. Only three of the studies were randomised controlled trials. A 'package' of largely unspecified editorial processes applied between acceptance and publication was associated with improved readability in two studies and improved reporting quality in another two studies, while another study showed mixed results after stricter editorial policies were introduced. More intensive editorial processes were associated with fewer errors in abstracts and references. Providing instructions to authors was associated with improved reporting of ethics requirements in one study and fewer errors in references in two studies, but no difference was seen in the quality of abstracts in one randomised controlled trial. Structuring generally improved the quality of abstracts, but increased their length. The reference accuracy studies showed a median citation error rate of 38% and a median quotation error rate of 20%. Surprisingly few studies have evaluated the effects of technical editing rigorously. However there is some evidence that the 'package' of technical editing used by biomedical journals does improve papers. A substantial number of references in biomedical articles are cited or quoted inaccurately.

7 CFR 3430.32 - Preliminary application review.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE COMPETITIVE AND NONCOMPETITIVE NON-FORMULA... Evaluation § 3430.32 Preliminary application review. Prior to technical examination, a preliminary review...

Analysis-Driven Design of Representations For Sensing-Action Systems

DTIC Science & Technology

2017-10-01

from the Defense Technical Information Center (DTIC) (http://www.dtic.mil). AFRL-RY-WP-TR-2017-0196 HAS BEEN REVIEWED AND IS APPROVED FOR...Layered Sensing Exploitation Division This report is published in the interest of scientific and technical information exchange, and its...collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources

An Ecological Framework for Monitoring Sustainable Management of Wildlife: A New Mexico Furbearer Example.

DTIC Science & Technology

1996-09-01

Understanding use relative to availability is necessary to manage wildlife harvest sustainably. We used ecological zones ( ecozones ) as a framework...ecological classification scheme, reviewed technical literature mapped species distribution among ecozones , assessed harvest, estimated sustainable extraction...other wildlife. Technical literature review of 70 key words and species names identified 534 citations regarding furbearers in ecozones shared by New

Curriculum Programs in Action, Their Administration and Evaluation; Report of a Conference Devoted to Description, Demonstration, and Evaluative Discussions of Innovative Programs in Vocational-Technical Education.

ERIC Educational Resources Information Center

San Francisco State Coll., CA. Center for Technological Education.

The presentation, review and evaluation of innovative vocational-technical curriculums in operation was the major function of a San Francisco conference sponsored jointly by the Center for Technical Education at San Francisco State College and the Center for Studies in Vocational and Technical Education at the University of Wisconsin. Major…

20 CFR 411.167 - What is an educational institution or a technical, trade or vocational school?

Code of Federal Regulations, 2010 CFR

2010-04-01

... ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Suspension of Continuing Disability Reviews for... accredited by a State-recognized or nationally recognized accrediting body. (b) Technical, trade or... State or accredited by a State-recognized or nationally recognized accrediting body to provide technical...

Technical Communicator: A New Model for the Electronic Resources Librarian?

ERIC Educational Resources Information Center

Hulseberg, Anna

2016-01-01

This article explores whether technical communicator is a useful model for electronic resources (ER) librarians. The fields of ER librarianship and technical communication (TC) originated and continue to develop in relation to evolving technologies. A review of the literature reveals four common themes for ER librarianship and TC. While the…

9 CFR 351.5 - Conditions of eligibility for certification service; review of applications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR...”); and such source materials will be rendered at the plant into technical animal fat eligible for export... the rendered technical animal fat described in paragraph (a)(1) will be identified and kept separated...

9 CFR 351.5 - Conditions of eligibility for certification service; review of applications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR...”); and such source materials will be rendered at the plant into technical animal fat eligible for export... the rendered technical animal fat described in paragraph (a)(1) will be identified and kept separated...

9 CFR 351.5 - Conditions of eligibility for certification service; review of applications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR...”); and such source materials will be rendered at the plant into technical animal fat eligible for export... the rendered technical animal fat described in paragraph (a)(1) will be identified and kept separated...

9 CFR 351.5 - Conditions of eligibility for certification service; review of applications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR...”); and such source materials will be rendered at the plant into technical animal fat eligible for export... the rendered technical animal fat described in paragraph (a)(1) will be identified and kept separated...

TADS and Technical Assistance: Readings on System Design, Needs Assessment, Consultation, and Evaluation.

ERIC Educational Resources Information Center

Trohanis, Pascal L., Ed.

The document reviews the technical assistance process used by TADS (Technical Assistance Development System), a project to provide support to HCEEP (Handicapped Children's Early Education Program) demonstration projects serving young handicapped children and their families. Chapter 1, by P. Trohanis, focuses on a number of questions that people…

1999 NASA High-Speed Research Program Aerodynamic Performance Workshop. Volume 1; Configuration Aerodynamics

NASA Technical Reports Server (NTRS)

Hahne, David E. (Editor)

1999-01-01

NASA's High-Speed Research Program sponsored the 1999 Aerodynamic Performance Technical Review on February 8-12, 1999 in Anaheim, California. The review was designed to bring together NASA and industry High-Speed Civil Transport (HSCT) Aerodynamic Performance technology development participants in the areas of Configuration Aerodynamics (transonic and supersonic cruise drag prediction and minimization), High Lift, and Flight Controls. The review objectives were to: (1) report the progress and status of HSCT aerodynamic performance technology development; (2) disseminate this technology within the appropriate technical communities; and (3) promote synergy among the scientists and engineers working on HSCT aerodynamics. In particular, single and midpoint optimized HSCT configurations, HSCT high-lift system performance predictions, and HSCT simulation results were presented, along with executive summaries for all the Aerodynamic Performance technology areas. The HSR Aerodynamic Performance Technical Review was held simultaneously with the annual review of the following airframe technology areas: Materials and Structures, Environmental Impact, Flight Deck, and Technology Integration. Thus, a fourth objective of the Review was to promote synergy between the Aerodynamic Performance technology area and the other technology areas of the HSR Program. This Volume 1/Part 1 publication covers configuration aerodynamics.

1999 NASA High-Speed Research Program Aerodynamic Performance Workshop. Volume 2; High Lift

NASA Technical Reports Server (NTRS)

Hahne, David E. (Editor)

1999-01-01

NASA's High-Speed Research Program sponsored the 1999 Aerodynamic Performance Technical Review on February 8-12, 1999 in Anaheim, California. The review was designed to bring together NASA and industry High-Speed Civil Transport (HSCT) Aerodynamic Performance technology development participants in the areas of Configuration Aerodynamics (transonic and supersonic cruise drag prediction and minimization), High Lift, and Flight Controls. The review objectives were to (1) report the progress and status of HSCT aerodynamic performance technology development; (2) disseminate this technology within the appropriate technical communities; and (3) promote synergy among die scientists and engineers working on HSCT aerodynamics. In particular, single and midpoint optimized HSCT configurations, HSCT high-lift system performance predictions, and HSCT simulation results were presented, along with executive summaries for all the Aerodynamic Performance technology areas. The HSR Aerodynamic Performance Technical Review was held simultaneously with the annual review of the following airframe technology areas: Materials and Structures, Environmental Impact, Flight Deck, and Technology Integration. Thus, a fourth objective of the Review was to promote synergy between the Aerodynamic Performance technology area and the other technology areas of the HSR Program. This Volume 2/Part 2 publication covers the tools and methods development session.

1999 NASA High-Speed Research Program Aerodynamic Performance Workshop. Volume 1; Configuration Aerodynamics

NASA Technical Reports Server (NTRS)

Hahne, David E. (Editor)

1999-01-01

NASA's High-Speed Research Program sponsored the 1999 Aerodynamic Performance Technical Review on February 8-12, 1999 in Anaheim, California. The review was designed to bring together NASA and industry High-Speed Civil Transport (HSCT) Aerodynamic Performance technology development participants in the areas of Configuration Aerodynamics (transonic and supersonic cruise drag prediction and minimization), High Lift, and Flight Controls. The review objectives were to (1) report the progress and status of HSCT aerodynamic performance technology development; (2) disseminate this technology within the appropriate technical communities; and (3) promote synergy among the scientists and engineers working on HSCT aerodynamics. In particular, single and midpoint optimized HSCT configurations, HSCT high-lift system performance predictions, and HSCT simulation results were presented, along with executive summaries for all the Aerodynamic Performance technology areas. The HSR Aerodynamic Performance Technical Review was held simultaneously with the annual review of the following airframe technology areas: Materials and Structures, Environmental Impact, Flight Deck, and Technology Integration. Thus, a fourth objective of the Review was to promote synergy between the Aerodynamic Performance technology area and the other technology areas of the HSR Program. This Volume 1/Part 2 publication covers the design optimization and testing sessions.

Technical Review of Retrieval and Closure Plans for the INEEL INTEC Tank Farm Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bamberger, Judith A; Burks, Barry L; Quigley, Keith D

2001-09-28

The purpose of this report is to document the conclusions of a technical review of retrieval and closure plans for the Idaho National Energy and Environmental Laboratory (INEEL) Idaho Nuclear Technology and Engineering Center (INTEC) Tank Farm Facility. In addition to reviewing retrieval and closure plans for these tanks, the review process served as an information exchange mechanism so that staff in the INEEL High Level Waste (HLW) Program could become more familiar with retrieval and closure approaches that have been completed or are planned for underground storage tanks at the Oak Ridge National Laboratory (ORNL) and Hanford sites. Thismore » review focused not only on evaluation of the technical feasibility and appropriateness of the approach selected by INEEL but also on technology gaps that could be addressed through utilization of technologies or performance data available at other DOE sites and in the private sector. The reviewers, Judith Bamberger of Pacific Northwest National Laboratory (PNNL) and Dr. Barry Burks of The Providence Group Applied Technology, have extensive experience in the development and application of tank waste retrieval technologies for nuclear waste remediation.« less

32 CFR 202.8 - Training RAB members.

Code of Federal Regulations, 2011 CFR

2011-07-01

... technologies, chemicals of concern, and sampling protocols, as well as informing them of the availability of independent technical advice and document review through EPA's Technical Assistant Grant program and DoD's...

32 CFR 202.8 - Training RAB members.

Code of Federal Regulations, 2012 CFR

2012-07-01

... technologies, chemicals of concern, and sampling protocols, as well as informing them of the availability of independent technical advice and document review through EPA's Technical Assistant Grant program and DoD's...

32 CFR 202.8 - Training RAB members.

Code of Federal Regulations, 2013 CFR

2013-07-01

... technologies, chemicals of concern, and sampling protocols, as well as informing them of the availability of independent technical advice and document review through EPA's Technical Assistant Grant program and DoD's...

Technical architecture of ONC-approved plans for statewide health information exchange.

PubMed

Barrows, Randolph C; Ezzard, John

2011-01-01

ONC-approved state plans for HIE were reviewed for descriptions and depictions of statewide HIE technical architecture. Review was complicated by non-standard organizational elements and technical terminology across state plans. Findings were mapped to industry standard, referenced, and defined HIE architecture descriptions and characteristics. Results are preliminary due to the initial subset of ONC-approved plans available, the rapid pace of new ONC-plan approvals, and continuing advancements in standards and technology of HIE, etc. Review of 28 state plans shows virtually all include a direct messaging component, but for participating entities at state-specific levels of granularity (RHIO, enterprise, organization/provider). About ½ of reviewed plans describe a federated architecture, and ¼ of plans utilize a single-vendor "hybrid-federated" architecture. About 1/3 of states plan to leverage new federal and open exchange technologies (DIRECT, CONNECT, etc.). Only one plan describes a centralized architecture for statewide HIE, but others combine central and federated architectural approaches.

Technical Architecture of ONC-Approved Plans For Statewide Health Information Exchange

PubMed Central

Barrows, Randolph C.; Ezzard, John

2011-01-01

ONC-approved state plans for HIE were reviewed for descriptions and depictions of statewide HIE technical architecture. Review was complicated by non-standard organizational elements and technical terminology across state plans. Findings were mapped to industry standard, referenced, and defined HIE architecture descriptions and characteristics. Results are preliminary due to the initial subset of ONC-approved plans available, the rapid pace of new ONC-plan approvals, and continuing advancements in standards and technology of HIE, etc. Review of 28 state plans shows virtually all include a direct messaging component, but for participating entities at state-specific levels of granularity (RHIO, enterprise, organization/provider). About ½ of reviewed plans describe a federated architecture, and ¼ of plans utilize a single-vendor “hybrid-federated” architecture. About 1/3 of states plan to leverage new federal and open exchange technologies (DIRECT, CONNECT, etc.). Only one plan describes a centralized architecture for statewide HIE, but others combine central and federated architectural approaches. PMID:22195059

Index to Nuclear Safety: a technical progress review by chronology, permuted title, and author, Volume 18 (1) through Volume 22 (6)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cottrell, W.B.; Passiakos, M.

This index to Nuclear Safety covers articles published in Nuclear Safety, Volume 18, Number 1 (January-February 1977) through Volume 22, Number 6 (November-December 1981). The index is divided into three section: a chronological list of articles (including abstracts), a permuted-title (KWIC) index, and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. Over 300 technical articles published in Nuclear Safety in the last 5 years are listed in this index.

An Approach to Tailoring Major Technical Reviews Based on Project Characteristics and Stakeholder Interests

NASA Technical Reports Server (NTRS)

Richstein, Alan B.; Nolte, Jerome T.; Pfarr, Barbara B.

2004-01-01

There are numerous technical reviews that occur throughout the systems engineering process life cycle. Many are well known by project managers and stakeholders such as developers and end users, an example of much is the critical design review (CDR). This major milestone for a large, complex new project may last two or more days, include an extensive agenda of topics, and entail hundreds of hours of developer time to prepare presentation materials and associated documents. Additionally, the weeks of schedule spent on review preparation is at least partly at the expense of other work. This paper suggests an approach for tailoring technical reviews, based on the project characteristics and the project manager s identification of the key stakeholders and understanding of their most important issues and considerations. With this insight the project manager can communicate to, manage expectations oc and establish formal agreement with the stakeholders as to which reviews, and at what depth, are most appropriate to achieve project success. The authors, coming from diverse organizations and backgrounds, have drawn on their personal experiences and summarized the best practices of their own organizations to create a common framework to provide guidance on the adaptation of design reviews to other system engineers.

Using Model-Based Systems Engineering to Provide Artifacts for NASA Project Life-cycle and Technical Reviews

NASA Technical Reports Server (NTRS)

Parrott, Edith L.; Weiland, Karen J.

2017-01-01

This paper is for the AIAA Space Conference. The ability of systems engineers to use model-based systems engineering (MBSE) to generate self-consistent, up-to-date systems engineering products for project life-cycle and technical reviews is an important aspect for the continued and accelerated acceptance of MBSE. Currently, many review products are generated using labor-intensive, error-prone approaches based on documents, spreadsheets, and chart sets; a promised benefit of MBSE is that users will experience reductions in inconsistencies and errors. This work examines features of SysML that can be used to generate systems engineering products. Model elements, relationships, tables, and diagrams are identified for a large number of the typical systems engineering artifacts. A SysML system model can contain and generate most systems engineering products to a significant extent and this paper provides a guide on how to use MBSE to generate products for project life-cycle and technical reviews. The use of MBSE can reduce the schedule impact usually experienced for review preparation, as in many cases the review products can be auto-generated directly from the system model. These approaches are useful to systems engineers, project managers, review board members, and other key project stakeholders.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Konynenburg, R.A.

In response to a request for the Director of the Los Alamos national Laboratory, several members of the staff of the Lawrence Livermore National Laboratory participated in a technical review of a draft paper by CD Bowman and F. Venneri dealing with the potential for nuclear criticality in the geologic disposal of fissile materials. This review consisted of a consideration of the technical issues raised in the draft paper, and did not include discussions with the authors.

Review of Military Mountain Medicine Technology and Research Barriers

DTIC Science & Technology

2011-09-01

NORTH ATLANTIC TREATY ORGANISATION RESEARCH AND TECHNOLOGY ORGANISATION AC/323(HFM-146)TP/387 www.rto.nato.int RTO TECHNICAL REPORT TR...montagne et les freins à la recherche) Final Report of Task Group HFM-146. Published September 2011 Distribution and Availability...323(HFM-146)TP/387 www.rto.nato.int RTO TECHNICAL REPORT TR-HFM-146 Review of Military Mountain Medicine Technology and Research Barriers (Point

Psychotherapy and Counseling in the Treatment of Drug Abuse [Technical Review] (Rockville, Maryland, May 18-19, 1989). National Institute on Drug Abuse Research Monograph Series 104.

ERIC Educational Resources Information Center

Onken, Lisa Simon; Blaine, Jack D.

This monograph is based on the papers from a technical review. These papers are included: (1) Psychotherapy and Counseling Research in Drug Abuse Treatment: Questions, Problems, and Solutions (Lisa Onken, Jack Blaine); (2) Psychotherapy and Counseling for Methadone-Maintained Opiate Addicts: Results of Research Studies (George Woody, A. T.…

Nuclear Materials Focus Area Fiscal Year 2002 Mid Year Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thiel, Elizabeth Chilcote

2002-05-01

The Nuclear Materials Focus Area (NMFA) held its annual mid-year review on February 12 and 14, 2002, in Santa Fe, New Mexico. The purpose of this review was to examine both the technical aspects and the programmatic aspects of its technology development program. The focus area activities were reviewed by a panel consisting of personnel representing the end users of the technologies, and technical experts in nuclear materials. This year's review was somewhat different than in the past, as the stress was on how well the various projects being managed through the NMFA aligned with the two thrust areas andmore » nine key goals and priorities recently issued by the Deputy Assistant Secretary for DOE's Office of Environmental Management (EM).« less

Nuclear Materials Focus Area Fiscal Year 2002 Mid Year Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thiel, E.C.; Fuhrman, P.W.

2002-05-30

The Nuclear Materials Focus Area (NMFA) held its annual mid-year review on February 12 and 14, 2002, in Santa Fe, New Mexico. The purpose of this review was to examine both the technical aspects and the programmatic aspects of its technology development program. The focus area activities were reviewed by a panel consisting of personnel representing the end users of the technologies, and technical experts in nuclear materials. This year's review was somewhat different than in the past, as the stress was on how well the various projects being managed through the NMFA aligned with the two thrust areas andmore » nine key goals and priorities recently issued by the Deputy Assistant Secretary for DOE's Office of Environmental Management (EM).« less

Technical review of the da Vinci surgical telemanipulator.

PubMed

Freschi, C; Ferrari, V; Melfi, F; Ferrari, M; Mosca, F; Cuschieri, A

2013-12-01

The da Vinci robotic surgical telemanipulator has been utilized in several surgical specialties for varied procedures, and the users' experiences have been widely published. To date, no detailed system technical analyses have been performed. A detailed review was performed of all publications and patents about the technical aspects of the da Vinci robotic system. Published technical literature on the da Vinci system highlight strengths and weaknesses of the robot design. While the system facilitates complex surgical operations and has a low malfunction rate, the lack of haptic (especially tactile) feedback and collisions between the robotic arms remain the major limitations of the system. Accurate, preplanned positioning of access ports is essential. Knowledge of the technical aspects of the da Vinci robot is important for optimal use. We confirmed the excellent system functionality and ease of use for surgeons without an engineering background. Research and development of the surgical robot has been predominant in the literature. Future trends address robot miniaturization and intelligent control design. Copyright © 2012 John Wiley & Sons, Ltd.

Astronomy Books of 1985: The Technical List.

ERIC Educational Resources Information Center

Fraknoi, Andrew

1986-01-01

Consists of the second part of the 1985 annotated review of technical books done by the Astronomical Society of the Pacific. This listing was primarily designed for graduate students or research scientists. (TW)

Do Technical Aids for Patient Handling Prevent Musculoskeletal Complaints in Health Care Workers?—A Systematic Review of Intervention Studies

PubMed Central

Hegewald, Janice; Berge, Wera; Heinrich, Philipp; Staudte, Ronny; Freiberg, Alice; Scharfe, Julia; Girbig, Maria; Nienhaus, Albert; Seidler, Andreas

2018-01-01

The physical load ensuing from the repositioning and moving of patients puts health care workers at risk of musculoskeletal complaints. Technical equipment developed to aid with patient handling should reduce physical strain and workload; however, the efficacy of these aids in preventing musculoskeletal disorders and complaints is still unclear. A systematic review of controlled intervention studies was conducted to examine if the risk of musculoskeletal complaints and disorders is reduced by technical patient handling equipment. MEDLINE®/PubMed®, EMBASE®, Allied and Complementary Medicine Database (AMED), and Cumulative Index of Nursing and Allied Health Literature (CINAHL®) were searched using terms for nursing, caregiving, technical aids, musculoskeletal injuries, and complaints. Randomized controlled trials and controlled before-after studies of interventions including technical patient handling equipment were included. The titles and abstracts of 9554 publications and 97 full-texts were screened by two reviewers. The qualitative synthesis included one randomized controlled trial (RCT) and ten controlled before-after studies. A meta-analysis of four studies resulted in a pooled risk ratio for musculoskeletal injury claims (post-intervention) of 0.78 (95% confidence interval 0.68–0.90). Overall, the methodological quality of the studies was poor and the results often based on administrative injury claim data, introducing potential selection bias. Interventions with technical patient handling aids appear to prevent musculoskeletal complaints, but the certainty of the evidence according to GRADE approach ranged from low to very low. PMID:29522440

Do Technical Aids for Patient Handling Prevent Musculoskeletal Complaints in Health Care Workers?-A Systematic Review of Intervention Studies.

PubMed

Hegewald, Janice; Berge, Wera; Heinrich, Philipp; Staudte, Ronny; Freiberg, Alice; Scharfe, Julia; Girbig, Maria; Nienhaus, Albert; Seidler, Andreas

2018-03-09

The physical load ensuing from the repositioning and moving of patients puts health care workers at risk of musculoskeletal complaints. Technical equipment developed to aid with patient handling should reduce physical strain and workload; however, the efficacy of these aids in preventing musculoskeletal disorders and complaints is still unclear. A systematic review of controlled intervention studies was conducted to examine if the risk of musculoskeletal complaints and disorders is reduced by technical patient handling equipment. MEDLINE ® /PubMed ® , EMBASE ® , Allied and Complementary Medicine Database (AMED), and Cumulative Index of Nursing and Allied Health Literature (CINAHL ® ) were searched using terms for nursing, caregiving, technical aids, musculoskeletal injuries, and complaints. Randomized controlled trials and controlled before-after studies of interventions including technical patient handling equipment were included. The titles and abstracts of 9554 publications and 97 full-texts were screened by two reviewers. The qualitative synthesis included one randomized controlled trial (RCT) and ten controlled before-after studies. A meta-analysis of four studies resulted in a pooled risk ratio for musculoskeletal injury claims (post-intervention) of 0.78 (95% confidence interval 0.68-0.90). Overall, the methodological quality of the studies was poor and the results often based on administrative injury claim data, introducing potential selection bias. Interventions with technical patient handling aids appear to prevent musculoskeletal complaints, but the certainty of the evidence according to GRADE approach ranged from low to very low.

Patterns of technical error among surgical malpractice claims: an analysis of strategies to prevent injury to surgical patients.

PubMed

Regenbogen, Scott E; Greenberg, Caprice C; Studdert, David M; Lipsitz, Stuart R; Zinner, Michael J; Gawande, Atul A

2007-11-01

To identify the most prevalent patterns of technical errors in surgery, and evaluate commonly recommended interventions in light of these patterns. The majority of surgical adverse events involve technical errors, but little is known about the nature and causes of these events. We examined characteristics of technical errors and common contributing factors among closed surgical malpractice claims. Surgeon reviewers analyzed 444 randomly sampled surgical malpractice claims from four liability insurers. Among 258 claims in which injuries due to error were detected, 52% (n = 133) involved technical errors. These technical errors were further analyzed with a structured review instrument designed by qualitative content analysis. Forty-nine percent of the technical errors caused permanent disability; an additional 16% resulted in death. Two-thirds (65%) of the technical errors were linked to manual error, 9% to errors in judgment, and 26% to both manual and judgment error. A minority of technical errors involved advanced procedures requiring special training ("index operations"; 16%), surgeons inexperienced with the task (14%), or poorly supervised residents (9%). The majority involved experienced surgeons (73%), and occurred in routine, rather than index, operations (84%). Patient-related complexities-including emergencies, difficult or unexpected anatomy, and previous surgery-contributed to 61% of technical errors, and technology or systems failures contributed to 21%. Most technical errors occur in routine operations with experienced surgeons, under conditions of increased patient complexity or systems failure. Commonly recommended interventions, including restricting high-complexity operations to experienced surgeons, additional training for inexperienced surgeons, and stricter supervision of trainees, are likely to address only a minority of technical errors. Surgical safety research should instead focus on improving decision-making and performance in routine operations for complex patients and circumstances.

48 CFR 315.303-70 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... by statute to use peer review for technical review of specified contracts, the requirements of those... requirements of this subpart. (1) The statutes that require such review and implementing regulations are as...

Mediation of Artefacts, Tools and Technical Objects: An International and French Perspective

ERIC Educational Resources Information Center

Impedovo, Maria Antonietta; Andreucci, Colette; Ginestié, Jacques

2017-01-01

In this article we present a review of literature on the concept of Artefact, Tool and Technical Object in the light of sociocultural approach. Particular attention is given to present and discuss the French research tradition on the Technical Object and Technological education. The aim is to give a broad perspective to explore the mediation…

Minnesota Technical College System: Library/Media Services Survey and Report.

ERIC Educational Resources Information Center

Olson, Lynette

This document presents a report on the Minnesota Technical College System's Library and Media Services. All 34 technical colleges were given a survey to prepare, a Library Advisory Board was established, and relevant literature and standards were reviewed to conduct and obtain data for this study. The report begins with the mission, values, and…

Flight Display Integration

DTIC Science & Technology

2006-10-01

public, including foreign nationals. National Technical Information Service 5285 Port Royal Road, Springfield VA 22161 Federal Government...Technical Information Center 8725 John J. Kingman Rd., STE 0944, Ft Belvoir VA 22060-6218 TECHNICAL REVIEW AND APPROVAL AFRL-HE-WP-TR-2006...and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302, and to the Office of Management and Budget, Paperwork Reduction

University-government relationships in the training of technical writers-editors

NASA Technical Reports Server (NTRS)

Stohrer, Freda F.; Pinelli, Thomas E.

1979-01-01

Traditional and nontraditional methods of training technical writers-editors are reviewed. Combining work experience with classroom instruction in the form of cooperative education provides a method of strengthening the Federal career service in professional occupations. The NASA Langley experience that successfully introduced students to the special demands of technical writing and editing is described.

Assessment of Technical Skills Competence in the Operating Room: A Systematic and Scoping Review.

PubMed

Fahim, Christine; Wagner, Natalie; Nousiainen, Markku T; Sonnadara, Ranil

2018-05-01

While academic accreditation bodies continue to promote competency-based medical education (CBME), the feasibility of conducting regular CBME assessments remains challenging. The purpose of this study was to identify evidence pertaining to the practical application of assessments that aim to measure technical competence for surgical trainees in a nonsimulated, operative setting. In August 2016, the authors systematically searched Medline, Embase, and the Cochrane Database of Systematic Reviews for English-language, peer-reviewed articles published in or after 1996. The title, abstract, and full text of identified articles were screened. Data regarding study characteristics, psychometric and measurement properties, implementation of assessment, competency definitions, and faculty training were extracted. The findings from the systematic review were supplemented by a scoping review to identify key strategies related to faculty uptake and implementation of CBME assessments. A total of 32 studies were included. The majority of studies reported reasonable scores of interrater reliability and internal consistency. Seven articles identified minimum scores required to establish competence. Twenty-five articles mentioned faculty training. Many of the faculty training interventions focused on timely completion of assessments or scale calibration. There are a number of diverse tools used to assess competence for intraoperative technical skills and a lack of consensus regarding the definition of technical competence within and across surgical specialties. Further work is required to identify when and how often trainees should be assessed and to identify strategies to train faculty to ensure timely and accurate assessment.

Barriers to Electronic Health Record Adoption: a Systematic Literature Review.

PubMed

Kruse, Clemens Scott; Kristof, Caitlin; Jones, Beau; Mitchell, Erica; Martinez, Angelica

2016-12-01

Federal efforts and local initiatives to increase adoption and use of electronic health records (EHRs) continue, particularly since the enactment of the Health Information Technology for Economic and Clinical Health (HITECH) Act. Roughly one in four hospitals not adopted even a basic EHR system. A review of the barriers may help in understanding the factors deterring certain healthcare organizations from implementation. We wanted to assemble an updated and comprehensive list of adoption barriers of EHR systems in the United States. Authors searched CINAHL, MEDLINE, and Google Scholar, and accepted only articles relevant to our primary objective. Reviewers independently assessed the works highlighted by our search and selected several for review. Through multiple consensus meetings, authors tapered articles to a final selection most germane to the topic (n = 27). Each article was thoroughly examined by multiple authors in order to achieve greater validity. Authors identified 39 barriers to EHR adoption within the literature selected for the review. These barriers appeared 125 times in the literature; the most frequently mentioned barriers were regarding cost, technical concerns, technical support, and resistance to change. Despite federal and local incentives, the initial cost of adopting an EHR is a common existing barrier. The other most commonly mentioned barriers include technical support, technical concerns, and maintenance/ongoing costs. Policy makers should consider incentives that continue to reduce implementation cost, possibly aimed more directly at organizations that are known to have lower adoption rates, such as small hospitals in rural areas.

Conduct of a Survey to Determine Why Blacks Do Not Have Sufficient Enrollment in Vocational-Technical Programs in Community Colleges, Area Vocational-Technical Centers and Secondary Schools, and Development of Strategies for Increasing the Number of Students Enrolling in Vocational-Technical Programs.

ERIC Educational Resources Information Center

West Virginia Research Coordinating Unit for Vocational Education, Huntington.

A project involving literature and demographic data reviews, survey development, survey administration, data analysis, and document preparation was conducted in West Virginia to determine why blacks do not have sufficient enrollments in vocational technical centers and secondary schools. Three separate multiple-choice questionnaires were developed…

INDEPENDENT REVIEW OF THE X-701B GROUNDWATER REMEDY, PORTSMOUTH, OHIO: TECHNICAL EVALUATION AND RECOMMENDATIONS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Looney, B.; Eddy-Dilek, C.; Costanza, J.

2008-12-15

The Department of Energy Portsmouth Paducah Project Office requested assistance from Department of Energy Office of Environmental Management (EM-22) to provide independent technical experts to evaluate past and ongoing remedial activities at the Portsmouth facility that were completed to address TCE contamination associated with the X-701B groundwater plume and to make recommendations for future efforts. The Independent Technical Review team was provided with a detailed and specific charter. The charter requested that the technical team first review the past and current activities completed for the X-701B groundwater remedy for trichloroethene (TCE) in accordance with a Decision Document that was issuedmore » by Ohio EPA on December 8, 2003 and a Work Plan that was approved by Ohio EPA on September 22, 2006. The remedy for X-701B divides the activities into four phases: Phase I - Initial Source Area Treatment, Phase II - Expanded Source Area Treatment, Phase III - Evaluation and Reporting, and Phase IV - Downgradient Remediation and Confirmation of Source Area Treatment. Phase I of the remedy was completed during FY2006, and DOE has now completed six oxidant injection events within Phase II. The Independent Technical Review team was asked to evaluate Phase II activities, including soil and groundwater results, and to determine whether or not the criteria that were defined in the Work Plan for the Phase II end point had been met. The following criteria are defined in the Work Plan as an acceptable Phase II end point: (1) Groundwater samples from the identified source area monitoring wells have concentrations below the Preliminary Remediation Goal (PRG) for TCE in groundwater, or (2) The remedy is no longer effective in removing TCE mass from the source area. In addition, the charter specifies that if the Review Team determines that the Phase II endpoint has not been reached, then the team should address the following issues: (1) If additional injection events are recommended, the team should identify the type of injection and target soil horizon for these injections; (2) Consider the feasibility of declaring Technical Impracticability and proceeding with the RCRA Cap for the X-701B; and (3) Provide a summary of other cost-effective technologies that could be implemented (especially for the lower Gallia). The Independent Technical Review team focused its evaluation solely on the X-701B source zone and contaminant plume. It did not review current or planned remedial activities at other plumes, waste areas, or landfills at the Portsmouth site, nor did it attempt to integrate such activities into its recommendations for X-701B. However, the ultimate selection of a remedy for X-701B by site personnel and regulators should take into account potentially synergistic efforts at other waste areas. Assessment of remedial alternatives in the context of site-wide management practices may reveal opportunities for leveraging and savings that would not otherwise be identified. For example, the cost of source-zone excavation or construction of a permeable reactive barrier at X-701B might be substantially reduced if contaminated soil could be buried on site at an existing or planned landfill. This allowance would improve the feasibility and competitiveness of both remedies. A comprehensive examination of ongoing and future environmental activities across the Portsmouth Gaseous Diffusion Plant is necessary to optimize the selection and timing of X-701B remediation with respect to cleanup efficiency, safety, and economics. A selected group of technical experts attended the technical workshop at the Portsmouth Gaseous Diffusion Plant from November 18 through 21, 2008. During the first day of the workshop, both contractor and DOE site personnel briefed the workshop participants and took them on a tour of the X-701B site. The initial briefing was attended by representatives of Ohio EPA who participated in the discussions. On subsequent days, the team reviewed baseline data and reports, were provided additional technical information from site personnel, evaluated work plans, determined critical issues and uncertainties, and recommended alternatives. This report documents the findings and recommendations of the independent technical review team.« less

A Critique of the Theoretical and Empirical Literature of the Use of Diagrams, Graphs, and Other Visual Aids in the Learning of Scientific-Technical Content from Expository Texts and Instruction

ERIC Educational Resources Information Center

Carifio, James; Perla, Rocco J.

2009-01-01

This article presents a critical review and analysis of key studies that have been done in science education and other areas on the effects and effectiveness of using diagrams, graphs, photographs, illustrations, and concept maps as "adjunct visual aids" in the learning of scientific-technical content. It also summarizes and reviews those studies…

Wastewater Characterization Survey, Vandenberg, AFB, CA.

DTIC Science & Technology

1991-03-01

ENVIRONMENTAL HEALTH DIRECTORATE L Brooks Air Force Base, Texas 78235-5000 A B 0 Mrch 1991 RFinal Technical Report for Period 25 September 1990 - 5 October...recommendation for use by the United States Air Force. The Public Affairs Office has reviewed this report , and it is releasable to the National Technical...Information Service, where it will be available to the general public, including foreign nations. This report has been reviewed and is approved for

Extracorporeal photopheresis: Review of technical aspects.

PubMed

Arora, Satyam; Setia, Rasika

2017-01-01

Extracorporeal photochemotherapy (ECP) is considered as an immune modulating therapy majorly targeting the T cells of the Immune system. ECP induces an anti-inflammatory condition with tolerogenic responses without inducing a global immunosuppression state which is a typical feature of other therapeutic options such as steroids. Clinical indication of ECP has grown over time since its initial applications. Our review discusses the technical aspects of the concept of photopheresis with the available methods for its clinical applications.

Mine Burial Assessment State-of the Art in Prediction and Modeling Workshop and Initiation of Technical Program

DTIC Science & Technology

2000-09-30

Burial Assessment State-of-the Art Science , Technology, and Modeling. A Review of Coastal Research, Modeling, and Naval Operational Needs in Shallow Water...the ONR Mine Burial Prediction Program are summarized below. 1) Completed comprehensive technical reports: a. Mine Burial Assessment, State-of-the Art ... Science , Technology, and Modeling. A review of Coastal Research, Modeling, and Naval Operational Needs in Shallow Water Environments with

Development of a Torque Sensor-Based Test Bed for Attitude Control System Verification and Validation

DTIC Science & Technology

2017-12-30

from the Defense Technical Information Center (DTIC) (http://www.dtic.mil). AFRL-RV-PS-TR-2018-0008 HAS BEEN REVIEWED AND IS APPROVED FOR...report is published in the interest of scientific and technical information exchange, and its publication does not constitute the Government’s approval... information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and

Youth at High Risk for Substance Abuse. Proceedings of a Technical Review on "Special Youth Populations--What Etiology Suggests about Prevention and Treatment Programming" (Rockville, Maryland, July 16-17, 1986).

ERIC Educational Resources Information Center

Brown, Barry S.; Mills, Arnold R.

This publication is based on papers and discussion from a technical review on etiology and prevention and treatment programming for special populations. Full transcripts were edited in preparing the reports of panel discussions and, in a few instances, phrases have been added to increase clarity. Four youthful populations (children of substance…

A case study in technology utilization: Fracture mechanics

NASA Technical Reports Server (NTRS)

1972-01-01

This review of NASA contributions to the technology of fracture mechanics illustrates a fundamental role of the Space Agency in a single technical area. While primarily pursuing its goal of minimizing the weight of flight hardware, NASA engineers have generated innovations having broad impact in nonaerospace communities. A review is given of how these specific NASA innovations are communicated to the technical community outside the Space Agency, and current application areas are outlined.

Northeast Artificial Intelligence Consortium (NAIC) Review of Technical Tasks. Volume 2, Part 2.

DTIC Science & Technology

1987-07-01

A-A19 774 NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUN (MIC) 1/5 YVIEN OF TEOICR. T.. (U) NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM SYRACUSE MY J...NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM (NAIC) *p,* ~ Review of Technical Tasks ,.. 12 PERSONAL AUTHOR(S) (See reverse) . P VI J.F. Allen, P.B. Berra...See reverse) /" I ABSTRACT (Coninue on ’.wrse if necessary and identify by block number) % .. *. -. ’ The Northeast Artificial Intelligence Consortium

Career and Technical Education Reforms and Comprehensive School Reforms in High Schools: Their Impact on Education Outcomes for At-Risk Youth. The Highlight Zone: Research @ Work.

ERIC Educational Resources Information Center

Castellano, Marisa; Stringfield, Samuel; Stone, James R., III

The impact of career and technical education (CTE) reforms and comprehensive school reforms in high schools on education outcomes for at-risk youth was examined in a review of research on current reforms. The review identified a series of individual, family and home, school, and community factors that can place students at risk of failing to…

AgRISTARS. Preliminary technical results review of FY81 experiments, volume 2: Fiscal year 1981/1982 "corn and soybeans pilot" experiment

NASA Technical Reports Server (NTRS)

1981-01-01

The performance of the technology exhibited significant proportion estimation errors, specifically, high mean error in both corn and soybeans area estimation. The data systems, technical approaches, and data assessment of the pilot experiment were reviewed. Results of proportion estimations procedure performance evaluations, and sensitivity evaluations are presented. The role of the pilot experiment in foreign technology development is discussed.

SAM Technical Review Committee Final Report: Summary and Key Recommendations from the Onsite TRC Meeting Held April 22-23, 2013

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blair, N.; Dobos, S.; Janzou, S.

2013-08-01

The System Advisor Model (SAM) is a broad and robust set of models and frameworks for analyzing both system performance and system financing. It does this across a range of technologies dominated by solar technologies including photovoltaics (PV) and concentrated solar power (CSP). The U.S. Department of Energy (DOE) Solar Energy Technology Program requested the SAM development team to review the photovoltaic performance modeling with the development community and specifically, with the independent engineering community. The report summarizes the major effort for this technical review committee (TRC).

History, Molecular Mechanisms, and Endoscopic Treatment of Barrett’s Esophagus

PubMed Central

Spechler, Stuart Jon; Fitzgerald, Rebecca C.; Prasad, Ganapathy A.; Wang, Kenneth K.

2010-01-01

This report is written as an adjunct to the American Gastroenterological Association Institute’s medical position statement and technical review on the management of Barrett’s esophagus, which will be published in the near future. Those documents will consider a number of broad questions on the diagnosis, clinical features, and management of patients with Barrett’s esophagus, and the reader is referred to the technical review for an in-depth discussion of those topics. In this report, we review historical, molecular, and endoscopic therapeutic aspects of Barrett’s esophagus that are of interest to clinicians and researchers. PMID:20080098

CIDR

Science.gov Websites

this process to the requirements of their study. Data from both reviewed and non-reviewed SNPs will be released. A technical filter will be applied to the non-reviewed SNPs to eliminate total assay failures

Steady state solutions to dynamically loaded periodic structures

NASA Technical Reports Server (NTRS)

Kalinowski, A. J.

1980-01-01

The general problem of solving for the steady state (time domain) dynamic response (i.e., NASTRAN rigid format-8) of a general elastic periodic structure subject to a phase difference loading of the type encountered in traveling wave propagation problems was studied. Two types of structural configurations were considered; in the first type, the structure has a repeating pattern over a span that is long enough to be considered, for all practical purposes, as infinite; in the second type, the structure has structural rotational symmetry in the circumferential direction. The theory and a corresponding set of DMAP instructions which permits the NASTRAN user to automatically alter the rigid format-8 sequence to solve the intended class of problems are presented. Final results are recovered as with any ordinary rigid format-8 solution, except that the results are only printed for the typical periodic segment of the structure. A simple demonstration problem having a known exact solution is used to illustrate the implementation of the procedure.

Ritz method for transient response in systems having unsymmetric stiffness

NASA Technical Reports Server (NTRS)

Butler, Thomas G.

1989-01-01

The DMAP coding was automated to such an extent by using the device of bubble vectors, that it is useable for analyses in its present form. This feasibility study demonstrates that the Ritz Method is so compelling as to warrant coding its modules in FORTRAN and organizing the resulting coding into a new Rigid Format. Even though this Ritz technique was developed for unsymmetric stiffness matrices, it offers advantages to problems with symmetric stiffnesses. If used for the symmetric case the solution would be simplified to one set of modes, because the adjoint would be the same as the primary. Its advantage in either type of symmetry over a classical eigenvalue modal expansion is that information density per Ritz mode is far richer than per eigenvalue mode; thus far fewer modes would be needed for the same accuracy and every mode would actively participate in the response. Considerable economy can be realized in adapting Ritz vectors for modal solutions. This new Ritz capability now makes NASTRAN even more powerful than before.

Enantioselective separation of racemic juvenile hormone III by normal-phase high-performance liquid chromatography and preparation of [(2)H(3)]juvenile hormone III as an internal standard for liquid chromatography-mass spectrometry quantification.

PubMed

Ichikawa, Akio; Ono, Hiroshi; Furuta, Kenjiro; Shiotsuki, Takahiro; Shinoda, Tetsuro

2007-08-17

Juvenile hormone III (JH III) racemate was prepared from methyl (2E,6E)-farnesoate via epoxidation with 3-chloroperbenzoic acid (mCPBA). Enantioselective separation of JH III was conducted using normal-phase high-performance liquid chromatography (HPLC) on a chiral stationary phase. [(2)H(3)]Methyl (2E,6E)-farnesoate was also prepared from (2E,6E)-farnesoic acid and [(2)H(4)]methanol (methanol-d(4)) using 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) and 4-dimethylaminopyridine (DMAP); the conjugated double bond underwent isomerization to some degree. Epoxidation of [(2)H(3)]methyl (2E,6E)-farnesoate with mCPBA gave a novel deuterium-substituted internal standard [(2)H(3)]JH III (JH III-d(3)). The standard curve was produced by linear regression using the peak area ratios of JH III and JH III-d(3) in liquid chromatography-mass spectrometry (LC-MS).

A noniterative improvement of Guyan reduction

NASA Technical Reports Server (NTRS)

Ganesan, N.

1993-01-01

In determining the natural modes and frequencies of a linear elastic structure, Guyan reduction is often used to reduce the size of the mass and stiffness matrices and the solution of the reduced system is obtained first. The reduced system modes are then expanded to the size of the original system by using a static transformation linking the retained degrees of freedom to the omitted degrees of freedom. In the present paper, the transformation matrix of Guyan reduction is modified to include additional terms from a series accounting for the inertial effects. However, the inertial terms are dependent on the unknown frequencies. A practical approximation is employed to compute the inertial terms without any iteration. This new transformation is implemented in NASTRAN using a DMAP sequence alter. Numerical examples using a cantilever beam illustrate the necessary condition for allowing a large number of additional terms in the proposed series correction of Guyan reduction. A practical example of a large model of the Plasma Motor Generator module to be flown on a Delta launch vehicle is also presented.

Computational physics and applied mathematics capability review June 8-10, 2010 (Advance materials to committee members)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Stephen R

2010-01-01

Los Alamos National Laboratory will review its Computational Physics and Applied Mathematics (CPAM) capabilities in 2010. The goals of capability reviews are to assess the quality of science, technology, and engineering (STE) performed by the capability, evaluate the integration of this capability across the Laboratory and within the scientific community, examine the relevance of this capability to the Laboratory's programs, and provide advice on the current and future directions of this capability. This is the first such review for CPAM, which has a long and unique history at the laboratory, starting from the inception of the Laboratory in 1943. Themore » CPAM capability covers an extremely broad technical area at Los Alamos, encompassing a wide array of disciplines, research topics, and organizations. A vast array of technical disciplines and activities are included in this capability, from general numerical modeling, to coupled mUlti-physics simulations, to detailed domain science activities in mathematics, methods, and algorithms. The CPAM capability involves over 12 different technical divisions and a majority of our programmatic and scientific activities. To make this large scope tractable, the CPAM capability is broken into the following six technical 'themes.' These themes represent technical slices through the CP AM capability and collect critical core competencies of the Laboratory, each of which contributes to the capability (and each of which is divided into multiple additional elements in the detailed descriptions of the themes in subsequent sections): (1) Computational Fluid Dynamics - This theme speaks to the vast array of scientific capabilities for the simulation of fluids under shocks, low-speed flow, and turbulent conditions - which are key, historical, and fundamental strengths of the laboratory; (2) Partial Differential Equations - The technical scope of this theme is the applied mathematics and numerical solution of partial differential equations (broadly defined) in a variety of settings, including particle transport, solvers, and plasma physics; (3) Monte Carlo - Monte Carlo was invented at Los Alamos, and this theme discusses these vitally important methods and their application in everything from particle transport, to condensed matter theory, to biology; (4) Molecular Dynamics - This theme describes the widespread use of molecular dynamics for a variety of important applications, including nuclear energy, materials science, and biological modeling; (5) Discrete Event Simulation - The technical scope of this theme represents a class of complex system evolutions governed by the action of discrete events. Examples include network, communication, vehicle traffic, and epidemiology modeling; and (6) Integrated Codes - This theme discusses integrated applications (comprised of all of the supporting science represented in Themes 1-5) that are of strategic importance to the Laboratory and the nation. The laboratory has in approximately 10 million source lines of code in over 100 different such strategically important applications. Of these themes, four of them will be reviewed during the 2010 review cycle: Themes 1, 2, 3, and 6. Because these capability reviews occur every three years, Themes 4 and 5 will be reviewed in 2013, along with Theme 6 (which will be reviewed during each review, owing to this theme's role as an integrator of the supporting science represented by the other 5 themes). Yearly written status reports will be provided to the Capability Review Committee Chair during off-cycle years.« less

7 CFR 622.32 - Reviews and approvals.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., DEPARTMENT OF AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Planning § 622.32 Reviews and approvals. (a) The watershed plan-environmental impact statement (or assessment) will be subject to internal technical reviews..., and a final review as stated in NRCS's National Watersheds Manual. (b) After thorough review by NRCS...

7 CFR 622.32 - Reviews and approvals.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., DEPARTMENT OF AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Planning § 622.32 Reviews and approvals. (a) The watershed plan-environmental impact statement (or assessment) will be subject to internal technical reviews..., and a final review as stated in NRCS's National Watersheds Manual. (b) After thorough review by NRCS...

7 CFR 622.32 - Reviews and approvals.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., DEPARTMENT OF AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Planning § 622.32 Reviews and approvals. (a) The watershed plan-environmental impact statement (or assessment) will be subject to internal technical reviews..., and a final review as stated in NRCS's National Watersheds Manual. (b) After thorough review by NRCS...

7 CFR 622.32 - Reviews and approvals.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., DEPARTMENT OF AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Planning § 622.32 Reviews and approvals. (a) The watershed plan-environmental impact statement (or assessment) will be subject to internal technical reviews..., and a final review as stated in NRCS's National Watersheds Manual. (b) After thorough review by NRCS...

7 CFR 622.32 - Reviews and approvals.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., DEPARTMENT OF AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Planning § 622.32 Reviews and approvals. (a) The watershed plan-environmental impact statement (or assessment) will be subject to internal technical reviews..., and a final review as stated in NRCS's National Watersheds Manual. (b) After thorough review by NRCS...

Idaho National Laboratory Directed Research and Development FY-2009

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2010-03-01

The FY 2009 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL - it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development. Established by Congress in 1991, LDRD proves its benefitmore » each year through new programs, intellectual property, patents, copyrights, publications, national and international awards, and new hires from the universities and industry, which helps refresh the scientific and engineering workforce. The benefits of INL's LDRD research are many as shown in the tables below. Last year, 91 faculty members from various universities contributed to LDRD research, along with 7 post docs and 64 students. Of the total invention disclosures submitted in FY 2009, 7 are attributable to LDRD research. Sixty three refereed journal articles were accepted or published, and 93 invited presentations were attributable to LDRD research conducted in FY 2009. The LDRD Program is administered in accordance with requirements set in DOE Order 413.2B, accompanying contractor requirements, and other DOE and federal requirements invoked through the INL contract. The LDRD Program is implemented in accordance with the annual INL LDRD Program Plan, which is approved by the DOE, Nuclear Energy Program Secretarial Office. This plan outlines the method the laboratory uses to develop its research portfolio, including peer and management reviews, and the use of other INL management systems to ensure quality, financial, safety, security and environmental requirements and risks are appropriately handled. The LDRD Program is assessed annually for both output and process efficiency to ensure the investment is providing expected returns on technical capability enhancement. The call for proposals and project selection process for the INL LDRD program begins typically in April, with preliminary budget allocations, and submittal of the technical requests for preproposals. A call for preproposals is made at this time as well, and the preparation of full proposals follows in June and closes in July. The technical and management review follows this, and the portfolio is submitted for DOE-ID concurrence in early September. Project initiation is in early October. The technical review process is independent of, and in addition to the management review. These review processes are very stringent and comprehensive, ensuring technical viability and suitable technical risk are encompassed within each project that is selected for funding. Each proposal is reviewed by two or three anonymous technical peers, and the reviews are consolidated into a cohesive commentary of the overall research based on criteria published in the call for proposals. A grade is assigned to the technical review and the review comments and grade are released back to the principal investigators and the managers interested in funding the proposals. Management criteria are published in the call for proposals, and management comments and selection results are available for principal investigator and other interested management as appropriate. The DOE Idaho Operations Office performs a final review and concurs on each project prior to project authorization, and on major scope/budget changes should they occur during the project's implementation. This report begins with several research highlights that exemplify the diversity of scientific and engineering research performed at the INL in FY 2009. Progress summaries for all projects are organized into sections reflecting the major areas of research focus at the INL. These sections begin with the DOE-NE Nuclear Science and Technology mission support area, followed by the National and Homeland Security and the Energy and Environmental Science and Technology areas. The major INL initiatives and the INL's Distinctive Signatures areas complete the project summaries. The appendices provide information on project relevance to DOE missions and major national programs as well as an author index, list of refereed publications and index of key terms.« less

Framework for incorporating simulation into urology training.

PubMed

Arora, Sonal; Lamb, Benjamin; Undre, Shabnam; Kneebone, Roger; Darzi, Ara; Sevdalis, Nick

2011-03-01

• Changes to working hours, new technologies and increased accountability have rendered the need for alternative training environments for urologists. • Simulation offers a promising arena for learning to take place in a safe, realistic setting. • Despite its benefits, the incorporation of simulation into urological training programmes remains minimal. • The current status and future directions of simulation for training in technical and non-technical skills are reviewed as they pertain to urology. • A framework is presented for how simulation-based training could be incorporated into the entire urological curriculum. • The literature on simulation in technical and non-technical skills training is reviewed, with a specific focus upon urology. • To fully integrate simulation into a training curriculum, its possibilities for addressing all the competencies required by a urologist must be realized. • At an early stage of training, simulation has been used to develop basic technical skills and cognitive skills, such as decision-making and communication. • At an intermediate stage, the studies focus upon more advanced technical skills learnt with virtual reality simulators. • Non-technical skills training would include leadership and could be delivered with in situ models. • At the final stage, experienced trainees can practise technical and non-technical skills in full crisis simulations situated within a fully-simulated operating rooms. • Simulation can provide training in the technical and non-technical skills required to be a competent urologist. • The framework presented may guide how best to incorporate simulation into training curricula. • Future work should determine whether acquired skills transfer to clinical practice and improve patient care. © 2010 THE AUTHORS. BJU INTERNATIONAL © 2010 BJU INTERNATIONAL.

Percutaneous radiofrequency ablation of hepatic tumours: factors affecting technical failure of artificial ascites formation using an angiosheath.

PubMed

Kang, T W; Lee, M W; Hye, M J; Song, K D; Lim, S; Rhim, H; Lim, H K; Cha, D I

2014-12-01

To evaluate the technical feasibility of artificial ascites formation using an angiosheath before percutaneous radiofrequency ablation (RFA) for hepatic tumours and to determine predictive factors affecting the technical failure of artificial ascites formation. This retrospective study was approved by the institutional review board. One hundred and thirteen patients underwent percutaneous RFA of hepatic tumours after trying to make artificial ascites using an angiosheath to avoid collateral thermal damage. The technical success rate of making artificial ascites using an angiosheath and conversion rate to other techniques after initial failure of making artificial ascites were evaluated. The technical success rate for RFA was assessed. In addition, potential factors associated with technical failure including previous history of transcatheter arterial chemoembolization (TACE) or RFA, type of abdominal surgery, and adjacent perihepatic structures were reviewed. Predictive factors for the technical failure of artificial ascites formation were analysed using multivariate analysis. The technical success rates of artificial ascites formation by angiosheath and that of RFA were 84.1% (95/113) and 97.3% (110/113), respectively. The conversion rate to other techniques after the failure of artificial ascites formation using an angiosheath was 15.9% (18/113). Previous hepatic resection was the sole independent predictive factor affecting the technical failure of artificial ascites formation (p<0.001, odds ratio = 29.03, 95% confidence interval: 4.56-184.69). Making artificial ascites for RFA of hepatic tumours using an angiosheath was technically feasible in most cases. However, history of hepatic resection was a significant predictive factor affecting the technical failure of artificial ascites formation. Copyright © 2014 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

A Case Study of Technical Assistance to Demonstration Programs for Young Handicapped Children. Part III.

ERIC Educational Resources Information Center

Behr, Shirley K.; And Others

The report describes the third and final year of a 3-year case study of the technical assistance process as implemented by the Technical Assistance Development System (TADS) for the staffs of two demonstration programs for preschool handicapped children and their families. Following a review of TADS and the two demonstration programs, the…

Assessment of lightweight mobile nuclear power systems. [for airborne vehicles

NASA Technical Reports Server (NTRS)

Anderson, J. L.; Rom, F. E.

1973-01-01

A review was made of lightweight mobile nuclear power systems (LMNPS). Data cover technical feasibility studies of LMNPS and airborne vehicles, mission studies, and non-technical conditions that are required to develop and use LMNPS.

Technical Guide for Addressing Petroleum Vapor Intrusion at Leaking Underground Storage Tank Sites

EPA Pesticide Factsheets

Review technical information for personnel EPA and implementing agencies for investigating and assessing petroleum vapor intrusion (PVI) at sites where petroleum hydrocarbons (PHCs) have been released from underground storage tanks (USTs).

Vocational Teacher Education at Ferris State College: Product of Constant Evaluation and Revision

ERIC Educational Resources Information Center

Storm, George

1974-01-01

The trade-technical education program at Ferris State College, Big Rapids, Michigan, is reviewed. The curriculum of the college, its intern programs, and the teacher preparation technical programs are described. (DS)

Expert Technical Committee : Bay Bridge Project Assessment meeting, January 6-8, 2005.

DOT National Transportation Integrated Search

2005-01-01

The Expert Technical Committee (ETC) was formed to provide an independent review and : assessment of the history and current status of the San Francisco-Oakland Bay Bridge East Span : Seismic Retrofit Cost Increases.

NASA Scientific and Technical Information Standards

NASA Technical Reports Server (NTRS)

2006-01-01

This document presents general recommended standards for documenting scientific and technical information (STI) from a number of scientific and engineering disciplines. It is a companion publication to NASA SP-7084, "Grammar, Punctuation, and Capitalization: A Handbook for Technical Writers and Editors," and is intended primarily for STI personnel and publishing personnel within NASA and who support NASA STI publishing. Section 1 gives an overview of NASA STI publications. Section 2 discusses figure preparation considerations. Section 3 covers table design, and Section 4 gives information about symbols and math related to STI publishing. Section 5 covers units of measure. Section 6 discusses References, and Section 7 discusses electronic documents. Section 8 covers information related to the review of STI prior to publication; this covers both technical and dissemination review and approval, including data quality. Section 9 discusses printing and dissemination related to STI, and Section 10 gives abbreviations and acronyms used in the document.

28 CFR 34.110 - Management of peer reviews.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Management of peer reviews. 34.110 Section 34.110 Judicial Administration DEPARTMENT OF JUSTICE OJJDP COMPETITION AND PEER REVIEW PROCEDURES Peer Review § 34.110 Management of peer reviews. A technical support contractor may assist in managing...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boing, L.E.

This paper presents an overview of the US experiences in the decommissioning technical area. Sections included are: (1) an overview of the magnitude of the problem, (2) a review of the US decommissioning process, (3) regulation of decommissioning, (4) regulatory and funding requirements for decommissioning, and (5) a general overview of all on-going and completed decommissioning projects to date in the US. The final section presents a review of some issues in the decommissioning area currently being debated in the technical specialists community.

The Training, Retention, and Assessment of Digital Skills: A Review and Integration of the Literature

DTIC Science & Technology

2006-11-01

Staff, G1 Authorized and approved for distribution: STANLEY M. HALPIN MICHELLE SAMS Acting Technical Director Acting Director Technical review by...research has found some benefit for spacing practice for motor skills. In an investigation of fuel and electrical repairers who were trained to test... electrical alternators using either massed or spaced training, the spaced training group made 40% fewer errors and took half the time to complete the tasks

Technical assessment of high energy astronomy Observatory-B (HEAO-B) Attitude Control and and Determination Subsystem (ACDS)

NASA Technical Reports Server (NTRS)

1976-01-01

The HEAO-B ACDS Review Team completed its four month assessment of the technical adequacy of the HEAO-B ACDS. As a result of its detailed analysis of the ACDS, the team found no reason why the ACDS will not perform its specified functions adequately. However, 23 concerns that point to potential difficulties were found and delineated; 18 of these are in the form of review item discrepancies.

Solid State Research: 1981:3

DTIC Science & Technology

1981-08-15

United States Government. The Public Affairs Office has reviewed this report, and it is releasable to the National Technical Information Service, where it...will be available to the general public, including foreign nationals. This technical report has been reviewed and is approved for publication. FOR...n D.. II .. I swat rai~. Bruv,d,~ S( . J.1x,la. L.i),’, It C. ’ . it. -11..... It. Bre,lab. ’ .1. IN. kalaaaaal. H. . M ~ Ia~ ~ . .1. [’aaa. I

Applications and limitations of radiomics

NASA Astrophysics Data System (ADS)

Yip, Stephen S. F.; Aerts, Hugo J. W. L.

2016-07-01

Radiomics is an emerging field in quantitative imaging that uses advanced imaging features to objectively and quantitatively describe tumour phenotypes. Radiomic features have recently drawn considerable interest due to its potential predictive power for treatment outcomes and cancer genetics, which may have important applications in personalized medicine. In this technical review, we describe applications and challenges of the radiomic field. We will review radiomic application areas and technical issues, as well as proper practices for the designs of radiomic studies.

Support for designing waste sorting systems: A mini review.

PubMed

Rousta, Kamran; Ordoñez, Isabel; Bolton, Kim; Dahlén, Lisa

2017-11-01

This article presents a mini review of research aimed at understanding material recovery from municipal solid waste. It focuses on two areas, waste sorting behaviour and collection systems, so that research on the link between these areas could be identified and evaluated. The main results presented and the methods used in the articles are categorised and appraised. The mini review reveals that most of the work that offered design guidelines for waste management systems was based on optimising technical aspects only. In contrast, most of the work that focused on user involvement did not consider developing the technical aspects of the system, but was limited to studies of user behaviour. The only clear consensus among the articles that link user involvement with the technical system is that convenient waste collection infrastructure is crucial for supporting source separation. This mini review reveals that even though the connection between sorting behaviour and technical infrastructure has been explored and described in some articles, there is still a gap when using this knowledge to design waste sorting systems. Future research in this field would benefit from being multidisciplinary and from using complementary methods, so that holistic solutions for material recirculation can be identified. It would be beneficial to actively involve users when developing sorting infrastructures, to be sure to provide a waste management system that will be properly used by them.

technical Hexachlorocyclohexane (t-HCH)

Integrated Risk Information System (IRIS)

technical Hexachlorocyclohexane ( t - HCH ) ; CASRN 608 - 73 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Asses

76 FR 28101 - Notice of Availability of NUREG-1950: ``Disposition of Public Comments and Technical Bases for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-13

....'' This document is a knowledge management transfer document associated with Revision 2 of NUREG-1801... Review of License Renewal Applications for Nuclear Power Plants.'' The technical changes that were made...

7 CFR 3401.17 - Review criteria.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION.... Overall scientific and technical quality of proposal 10 2. Scientific and technical quality of the.... Feasibility of attaining objectives; adequacy of professional training and experience, facilities and...

MOVES Model Review Work Group

EPA Pesticide Factsheets

The FACA MOVES Review Work Group was formed under the Mobile Sources Technical Review Subcommittee (MSTRS), and is charged to provide input to EPA via the MSTRS and the Clean Air Act Advisory Committee on specific issues regarding MOVES development.

MELCOR Peer Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyack, B.E.; Dhir, V.K.; Gieseke, J.A.

1992-03-01

MELCOR is a fully integrated, engineering-level computer code that models the progression of severe accidents in light water reactor nuclear power plants. The newest version of MELCOR is Version 1.8.1, July 1991. MELCOR development has reached the point that the United States Nuclear Regulatory Commission sponsored a broad technical review by recognized experts to determine or confirm the technical adequacy of the code for the serious and complex analyses it is expected to perform. For this purpose, an eight-member MELCOR Peer Review Committee was organized. The Committee has completed its review of the MELCOR code: the review process and findingsmore » of the MELCOR Peer Review Committee are documented in this report. The Committee has determined that recommendations in five areas are appropriate: (1) MELCOR numerics, (2) models missing from MELCOR Version 1.8.1, (3) existing MELCOR models needing revision, (4) the need for expanded MELCOR assessment, and (5) documentation.« less

Heterobimetallic porphyrin complexes displaying triple dynamics: coupled metal motions controlled by constitutional evolution.

PubMed

Le Gac, Stéphane; Fusaro, Luca; Roisnel, Thierry; Boitrel, Bernard

2014-05-07

A bis-strap porphyrin ligand (1), with an overhanging carboxylic acid group on each side of the macrocycle, has been investigated toward the formation of dynamic libraries of bimetallic complexes with Hg(II), Cd(II), and Pb(II). Highly heteroselective metalation processes occurred in the presence of Pb(II), with Hg(II) or Cd(II) bound out-of-plane to the N-core and "PbOAc" bound to a carboxylate group of a strap on the opposite side. The resulting complexes, 1(Hg)·PbOAc and 1(Cd)·PbOAc, display three levels of dynamics. The first is strap-level (interactional dynamics), where the PbOAc moiety swings between the left and right side of the strap owing to a second sphere of coordination with lateral amide functions. The second is ligand-level (motional dynamics), where 1(Hg)·PbOAc and 1(Cd)·PbOAc exist as two degenerate states in equilibrium controlled by a chemical effector (AcO(-)). The process corresponds to a double translocation of the metal ions according to an intramolecular migration of Hg(II) or Cd(II) through the N-core, oscillating between the two equivalent overhanging carbonyl groups, coupled to an intermolecular pathway for PbOAc exchanging between the two equivalent overhanging carboxylate groups (N-core(up) ⇆ N-core(down) coupled to strap(down) ⇆ strap(up), i.e., coupled motion #1 in the abstract graphic). The third is library-level (constitutional dynamics), where a dynamic constitutional evolution of the system was achieved by the successive addition of two chemical effectors (DMAP and then AcO(-)). It allowed shifting equilibrium forward and backward between 1(Hg)·PbOAc and the corresponding homobimetallic complexes 1(Hg2)·DMAP and 1(Pb)·PbOAc. The latter displays a different ligand-level dynamics, in the form of an intraligand coupled migration of the Pb(II) ions (N-core(up) ⇆ strap(up) coupled to strap(down) ⇆ N-core(down), i.e., coupled motion #2 in the abstract graphic). In addition, the neutral "bridged" complexes 1HgPb and 1CdPb, with the metal ions on opposite sides both bound to the N-core and to a carboxylate of a strap, were structurally characterized. These results establish an unprecedented approach in supramolecular coordination chemistry, by considering the reversible interaction of a metal ion with the porphyrin N-core as a new source of self-organization processes. This work should provide new inspirations for the design of innovative adaptative materials and devices.

A Review of Hydrogen/Halogen Flow Cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cho, Kyu Taek; Tucker, Michael C.; Weber, Adam Z.

Flow batteries provide an energy-storage solution for various grid-related stability and service issues that arise as renewable-energy-generation technologies are adopted. Among the most promising flow-battery systems are those using hydrogen/halogen redox couples, which promise the possibility of meeting the cost target of the US Department of Energy (DOE), due to their fast and reversible kinetics and low materials cost. However, significant critical issues and barriers for their adoption remain. In this review of halogen/hydrogen systems, technical and performance issues, and research and development progress are reviewed. The information in this review can be used as a technical guide for researchmore » and development of related redox-flow-battery systems and other electrochemical technologies.« less

Sandia Review of High Bridge Associates Report: Comparison of Plutonium Disposition Alternatives: WIPP Diluted Plutonium Storage and MOX Fuel Irradiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoemaker, Paul E.; Hardin, Ernest; Park, HeeHo Daniel

The subject report from High Bridge Associates (HBA) was issued on March 2, 2016, in reaction to a U.S. Department of Energy (DOE) program decision to pursue down-blending of surplus Pu and geologic disposal at the Waste Isolation Pilot Plant (WIPP). Sandia National Laboratories was requested by the DOE to review the technical arguments presented in the HBA report. Specifically, this review is organized around three technical topics: criticality safety, radiological release limits, and thermal impacts. Questions raised by the report pertaining to legal and regulatory requirements, safeguards and security, international agreements, and costing of alternatives, are beyond the scopemore » of this review.« less

A Review of Hydrogen/Halogen Flow Cells

DOE PAGES

Cho, Kyu Taek; Tucker, Michael C.; Weber, Adam Z.

2016-05-17

Flow batteries provide an energy-storage solution for various grid-related stability and service issues that arise as renewable-energy-generation technologies are adopted. Among the most promising flow-battery systems are those using hydrogen/halogen redox couples, which promise the possibility of meeting the cost target of the US Department of Energy (DOE), due to their fast and reversible kinetics and low materials cost. However, significant critical issues and barriers for their adoption remain. In this review of halogen/hydrogen systems, technical and performance issues, and research and development progress are reviewed. The information in this review can be used as a technical guide for researchmore » and development of related redox-flow-battery systems and other electrochemical technologies.« less

Computational physics and applied mathematics capability review June 8-10, 2010

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Stephen R

2010-01-01

Los Alamos National Laboratory will review its Computational Physics and Applied Mathematics (CPAM) capabilities in 2010. The goals of capability reviews are to assess the quality of science, technology, and engineering (STE) performed by the capability, evaluate the integration of this capability across the Laboratory and within the scientific community, examine the relevance of this capability to the Laboratory's programs, and provide advice on the current and future directions of this capability. This is the first such review for CPAM, which has a long and unique history at the Laboratory, starting from the inception of the Laboratory in 1943. Themore » CPAM capability covers an extremely broad technical area at Los Alamos, encompassing a wide array of disciplines, research topics, and organizations. A vast array of technical disciplines and activities are included in this capability, from general numerical modeling, to coupled multi-physics simulations, to detailed domain science activities in mathematics, methods, and algorithms. The CPAM capability involves over 12 different technical divisions and a majority of our programmatic and scientific activities. To make this large scope tractable, the CPAM capability is broken into the following six technical 'themes.' These themes represent technical slices through the CPAM capability and collect critical core competencies of the Laboratory, each of which contributes to the capability (and each of which is divided into multiple additional elements in the detailed descriptions of the themes in subsequent sections), as follows. Theme 1: Computational Fluid Dynamics - This theme speaks to the vast array of scientific capabilities for the simulation of fluids under shocks, low-speed flow, and turbulent conditions - which are key, historical, and fundamental strengths of the Laboratory. Theme 2: Partial Differential Equations - The technical scope of this theme is the applied mathematics and numerical solution of partial differential equations (broadly defined) in a variety of settings, including particle transport, solvers, and plasma physics. Theme 3: Monte Carlo - Monte Carlo was invented at Los Alamos. This theme discusses these vitally important methods and their application in everything from particle transport, to condensed matter theory, to biology. Theme 4: Molecular Dynamics - This theme describes the widespread use of molecular dynamics for a variety of important applications, including nuclear energy, materials science, and biological modeling. Theme 5: Discrete Event Simulation - The technical scope of this theme represents a class of complex system evolutions governed by the action of discrete events. Examples include network, communication, vehicle traffic, and epidemiology modeling. Theme 6: Integrated Codes - This theme discusses integrated applications (comprised of all of the supporting science represented in Themes 1-5) that are of strategic importance to the Laboratory and the nation. The Laboratory has in approximately 10 million source lines of code in over 100 different such strategically important applications. Of these themes, four of them will be reviewed during the 2010 review cycle: Themes 1,2, 3, and 6. Because these reviews occur every three years, Themes 4 and 5 will be reviewed in 2013, along with Theme 6 (which will be reviewed during each review, owing to this theme's role as an integrator of the supporting science represented by the other five themes). Yearly written status reports will be provided to the CPAM Committee Chair during off-cycle years.« less

Assuring Crew Health Protection

NASA Technical Reports Server (NTRS)

Robinson, Judith L.

2007-01-01

Amongst the recommendation of the Columbia Accident Investigation Board (CAIB) were the establishment of an independent technical authorities, one of which is the Health and Medical Technical Authority. This viewgraph presentation reviews the work of this Technical Authority in maintaining standards that are aimed at implementing health and medical policy, responding to medical events and emergencies consistent with acceptable levels defined by standards and providing expertise for program milestones.

Educational Television Personnel's Review of the Technical Quality, Content Criteria, and Marketability of AEL's "Around the Bend" Pilot Tapes. Technical Report No. 31.

ERIC Educational Resources Information Center

Shively, Joe E.

In order to determine whether Appalachia Educational Laboratory (AEL) had the capability of producing a TV series of high technical quality with content that met criteria designed for the selection of children's television programs, a pilot tape produced by AEL was submitted for rating to educational television (ETV) specialists from the State…

PET/MRI – Technical Review

PubMed Central

Muzic, Raymond F.; DiFilippo, Frank P.

2015-01-01

PET/MR is a hybrid imaging technology with the potential to combine the molecular and functional information of PET with the soft-tissue contrast of MR. Herein we review the technical features and challenges of putting these different technologies together. We emphasize the conceptual to make the material accessible to a wide audience. We begin by reviewing PET/CT, a more mature multi-modality imaging technology, to provide a basis for comparison to the history of PET/MR development. We discuss the motivation and challenges of PET/MR and different approaches that have been used to meet the challenges. We conclude with a speculation about the future of this exciting imaging method. PMID:25497909

Reviews of the Comprehensive Nuclear-Test-Ban Treaty and U.S. security

NASA Astrophysics Data System (ADS)

Jeanloz, Raymond

2017-11-01

Reviews of the Comprehensive Nuclear-Test-Ban Treaty (CTBT) by the National Academy of Sciences concluded that the United States has the technical expertise and physical means to i) maintain a safe, secure and reliable nuclear-weapons stockpile without nuclear-explosion testing, and ii) effectively monitor global compliance once the Treaty enters into force. Moreover, the CTBT is judged to help constrain proliferation of nuclear-weapons technology, so it is considered favorable to U.S. security. Review of developments since the studies were published, in 2002 and 2012, show that the study conclusions remain valid and that technical capabilities are better than anticipated.

28 CFR 33.12 - Establishment of State Office.

Code of Federal Regulations, 2011 CFR

2011-07-01

... received from the Bureau of Justice Assistance, including receipt, review, processing, monitoring, progress and financial report review, technical assistance, grant adjustments, accounting, auditing, and fund...

28 CFR 33.12 - Establishment of State Office.

Code of Federal Regulations, 2010 CFR

2010-07-01

... received from the Bureau of Justice Assistance, including receipt, review, processing, monitoring, progress and financial report review, technical assistance, grant adjustments, accounting, auditing, and fund...

75 FR 44968 - Office of the Secretary, Office of the Assistant Secretary for Planning and Evaluation; Technical...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-30

... Trustees) establish a panel of technical experts to review the methods used in the HI and SMI annual... care, and alternate projection methodologies. The panel may also examine other methodological issues...

Technical Review of the Domestic Nuclear Detection Office Transformational and Applied Research Directorate’s Research and Development Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lavietes, Anthony; Trebes, James; Borchers, Robert

2013-01-01

At the request of the Domestic Nuclear Detection Office (DNDO), a Review Committee comprised of representatives from the American Physical Society (APS) Panel on Public Affairs (POPA) and the Institute of Electrical and Electronics Engineers (IEEE) Nuclear and Plasma Sciences Society (NPSS) performed a technical review of the DNDO Transformational and Applied Research Directorate (TARD) research and development program. TARD’s principal objective is to address gaps in the Global Nuclear Detection Architecture (GNDA) through improvements in the performance, cost, and operational burden of detectors and systems. The charge to the Review Committee was to investigate the existing TARD research andmore » development plan and portfolio, recommend changes to the existing plan, and recommend possible new R&D areas and opportunities. The Review Committee has several recommendations.« less

Economic Evaluation of Computerized Structural Analysis

NASA Technical Reports Server (NTRS)

Fortin, P. E.

1985-01-01

This completed effort involved a technical and economic study of the capabilities of computer programs in the area of structural analysis. The applicability of the programs to NASA projects and to other users was studied. The applications in other industries was explored including both research and development and applied areas. The costs of several alternative analysis programs were compared. A literature search covered applicable technical literature including journals, trade publications and books. In addition to the literature search, several commercial companies that have developed computerized structural analysis programs were contacted and their technical brochures reviewed. These programs include SDRC I-DEAS, MSC/NASTRAN, SCADA, SUPERSAP, NISA/DISPLAY, STAAD-III, MICAS, GTSTRUDL, and STARS. These programs were briefly reviewed as applicable to NASA projects.

Proceedings of a Conference on a Comprehensive Technical Review of Human Factors Technology in the Design-for-Maintainers Held at Pensacola Beach, Florida on 9-11 March 1982,

DTIC Science & Technology

1982-03-11

Lowery, 1969; Crawford & Altman, 1972; Rigney, Cremer , & Towne, 1965; Topmiller, 1964; see Hsu & Theisen, these Proceedings for a review) suggest...Factors Technical Memorandum No. 6021-1982-05). Warminster, PA: Naval Air Development Center, August 1982. Rigney, J. W., Cremer , R. H., & Towne, D. M. The...changes in the micro-elements. Several projects have employed time-synthesis simulation with generally positive results (Rigney, Cremer , Towne, & Mason

Notional Scoring for Technical Review Weighting As Applied to Simulation Credibility Assessment

NASA Technical Reports Server (NTRS)

Hale, Joseph Peter; Hartway, Bobby; Thomas, Danny

2008-01-01

NASA's Modeling and Simulation Standard requires a credibility assessment for critical engineering data produced by models and simulations. Credibility assessment is thus a "qualifyingfactor" in reporting results from simulation-based analysis. The degree to which assessors should be independent of the simulation developers, users and decision makers is a recurring question. This paper provides alternative "weighting algorithms" for calculating the value-added for independence of the levels of technical review defined for the NASA Modeling and Simulation Standard.

Design Review and Analysis | Water Power | NREL

Science.gov Websites

Design Review and Analysis Design Review and Analysis NREL is leveraging its 35 years of experience devices and components. As part of this effort, NREL researchers provide industry partners with design reviews and analyses. In addition to design reviews, NREL offers technical assistance to solve specific

77 FR 75173 - Comprehensive Assessment of the Process for the Review of Device Submissions; Request for Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

... performing the technical analysis, management assessment, and program evaluation tasks required to address... premarket reviews that meet regulatory review standards. 2. Analysis of elements of the review process... process. This includes analysis of root causes for inefficiencies that may affect review performance and...

Aircraft digital flight control technical review

NASA Technical Reports Server (NTRS)

Davenport, Otha B.; Leggett, David B.

1993-01-01

The Aircraft Digital Flight Control Technical Review was initiated by two pilot induced oscillation (PIO) incidents in the spring and summer of 1992. Maj. Gen. Franklin (PEO) wondered why the Air Force development process for digital flight control systems was not preventing PIO problems. Consequently, a technical review team was formed to examine the development process and determine why PIO problems continued to occur. The team was also to identify the 'best practices' used in the various programs. The charter of the team was to focus on the PIO problem, assess the current development process, and document the 'best practices.' The team reviewed all major USAF aircraft programs with digital flight controls, specifically, the F-15E, F-16C/D, F-22, F-111, C-17, and B-2. The team interviewed contractor, System Program Office (SPO), and Combined Test Force (CTF) personnel on these programs. The team also went to NAS Patuxent River to interview USN personnel about the F/A-18 program. The team also reviewed experimental USAF and NASA systems with digital flight control systems: X-29, X-31, F-15 STOL and Maneuver Technology Demonstrator (SMTD), and the Variable In-Flight Stability Test Aircraft (VISTA). The team also discussed the problem with other experts in the field including Ralph Smith and personnel from Calspan. The major conclusions and recommendations from the review are presented.

Technical Publications

Science.gov Websites

peer-reviewed journal Conference reports Technical memos documenting equipment or other technology Science, HEP User Facility. Fermilab is managed by Fermi Research Alliance, LLC (FRA), acting under data, apparatus, product, or process disclosed, or represents that its use would not infringe privately

The function of report components in the screening and reading of technical reports

NASA Technical Reports Server (NTRS)

Pinelli, T. E.; Cordle, V. M.; Vondran, R. F.

1984-01-01

A reader preference survey of engineers and scientists at the NASA Langley Research Center and in three professional/technical societies was conducted to determine the opinions of report users and producers concerning the format (organization) of NASA technical reports and the usage of technical report components. The survey questionnaire contained fourteen questions covering twelve survey topics. This article reports the findings of two survey topics: the components initially reviewed or read to determine whether to read a report in its entirety and the order in which report components are read.

2008 annual merit review

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2009-01-18

The 2008 DOE Vehicle Technologies Program Annual Merit Review was held February 25-28, 2008 in Bethesda, Maryland. The review encompassed all of the work done by the Vehicle Technologies Program: a total of 280 individual activities were reviewed, by a total of just over 100 reviewers. A total of 1,908 individual review responses were received for the technical reviews, and an additional 29 individual review responses were received for the plenary session review.

Diagnostics of Technical Condition of Gear Units of Belt Conveyors for the Aggregate of Methods of Nondestructive Testing

NASA Astrophysics Data System (ADS)

Kuzin, Evgeny G.; Gerike, Boris L.; Drozdenko, Yuriy V.; Lupiy, Michael G.; Grigoryeva, Natalya V.

2017-10-01

The article reviews the issues of complex use of methods of technical diagnostics of gearboxes for belt conveyors, with the aim of creating an effective system of maintenance. The article is showing the results of the evaluation of the technical condition of the drives of belt conveyors based on vibration monitoring and thermal parameters, and analysis of lubricating oil.

State Department Early Childhood Education Program Specialists' Review of the Content and Technical Quality of AEL's "Around the Bend" Pilot Tapes. Technical Report No. 30.

ERIC Educational Resources Information Center

Shively, Joe E.

In order to determine whether Appalachia Educational Laboratory (AEL) had the capacity to produce a TV series of technical quality and whose content meets criteria designed for the selection of children's television programs, two pilot tapes were produced by AEL and submitted for rating to seven early childhood education specialists from seven…

Human research ethics committees in technical universities.

PubMed

Koepsell, David; Brinkman, Willem-Paul; Pont, Sylvia

2014-07-01

Human research ethics has developed in both theory and practice mostly from experiences in medical research. Human participants, however, are used in a much broader range of research than ethics committees oversee, including both basic and applied research at technical universities. Although mandated in the United States, the United Kingdom, Canada, and Australia, non-medical research involving humans need not receive ethics review in much of Europe, Asia, Latin America, and Africa. Our survey of the top 50 technical universities in the world shows that, where not specifically mandated by law, most technical universities do not employ ethics committees to review human studies. As the domains of basic and applied sciences expand, ethics committees are increasingly needed to guide and oversee all such research regardless of legal requirements. We offer as examples, from our experience as an ethics committee in a major European technical university, ways in which such a committee provides needed services and can help ensure more ethical studies involving humans outside the standard medical context. We provide some arguments for creating such committees, and in our supplemental article, we provide specific examples of cases and concerns that may confront technical, engineering, and design research, as well as outline the general framework we have used in creating our committee. © The Author(s) 2014.

7 CFR 3400.21 - Scientific peer review for research activities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 15 2011-01-01 2011-01-01 false Scientific peer review for research activities. 3400... § 3400.21 Scientific peer review for research activities. Scientific peer review is an evaluation of a... with the scientific knowledge and technical skills to conduct the proposed research work. Peer...

EPA's 2007 Report on the Environment: Science Report (Sab Review Draft)

EPA Science Inventory

The EPA's 2007 Report on the Environment: Science Report (SAB Review Draft), formally known as the EPA's Report on the Environment - Technical Document, was released for public review and comment prior to the Science Advisory Board's (SAB) meeting and review held in July 2007. Co...

Method for Examination and Documentation of Basic Information and Metadata from Published Reports Relevant to the Study of Stormwater Runoff Quality

USGS Publications Warehouse

Dionne, Shannon G.; Granato, Gregory E.; Tana, Cameron K.

1999-01-01

A readily accessible archive of information that is valid, current, and technically defensible is needed to make informed highway-planning, design, and management decisions. The National Highway Runoff Water-Quality Data and Methodology Synthesis (NDAMS) is a cataloging and assessment of the documentation of information relevant to highway-runoff water quality available in published reports. The report review process is based on the NDAMS review sheet, which was designed by the USGS with input from the FHWA, State transportation agencies, and the regulatory community. The report-review process is designed to determine the technical merit of the existing literature in terms of current requirements for data documentation, data quality, quality assurance and quality control (QA/QC), and technical issues that may affect the use of historical data. To facilitate the review process, the NDAMS review sheet is divided into 12 sections: (1) administrative review information, (2) investigation and report information, (3) temporal information, (4) location information (5) water-quality-monitoring information, (6) sample-handling methods, (7) constituent information, (8) sampling focus and matrix, (9) flow monitoring methods, (10) field QA/QC, (11) laboratory, and (12) uncertainty/error analysis. This report describes the NDAMS report reviews and metadata documentation methods and provides an overview of the approach and of the quality-assurance and quality-control program used to implement the review process. Detailed information, including a glossary of relevant terms, a copy of the report-review sheets, and reportreview instructions are completely documented in a series of three appendixes included with this report. Therefore the reviews are repeatable and the methods can be used by transportation research organizations to catalog new reports as they are published.

Audit Report on "Work for Others Performed by the Department of Energy for the Department of Defense"

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Pursuant to the Atomic Energy Act of 1954, as amended, and the Economy Act of 1932, the Department of Energy and its semi-autonomous National Nuclear Security Administration (NNSA) provide research and technical assistance to other Federal agencies on a reimbursable, full cost recovery basis through the Work for Others (WFO) program. For the vast majority of WFO technical projects, Department Federal officials furnish administrative project oversight while the actual detailed scientific or technical work is completed by the Department's 'management and operating' contractors. These contractors are awarded a special contract type specifically created under the Federal Acquisition Regulation to managemore » and operate Department sites and facilities, including sophisticated laboratories and technical centers, on a government-owned, contractor-operated basis. With annual expenditures exceeding $1 billion, the Department of Defense (DoD) is one of the Department's largest WFO customers. Work performed for DoD at the Department's national laboratories and other facilities includes highly technical research in areas such as nuclear weapons systems, counter-terrorism, and in-theater troop support. The National Defense Authorization Act for Fiscal Year (FY) 2009, required the Inspectors General of the DoD and the Department to review procurement methods to determine whether the Department complied with DoD procurement requirements and/or whether alternative procurement policies were in place. In response, we focused our review on projects performed by NNSA because it completes the vast majority (approximately $900 million in FY 2008) of the Department's work for DoD. As part of this effort, and, at the specific request of the DoD Office of Inspector General (DoD OIG), we identified the universe of WFO technical projects that received new funding in the fourth quarter of FY 2008 at NNSA sites. We independently reviewed a judgmental sample of 11 projects selected by the DoD OIG to meet the objectives of this audit. Our review revealed that NNSA managed DoD WFO technical projects in a manner consistent with requirements of the Atomic Energy Act of 1954, the Federal Acquisition Regulation, and the Department's implementing guidance, the Department of Energy Acquisition Regulation. Because of the very nature of the Department's management and operating contracting model, WFO projects may not be technically compliant with DoD procurement regulations in certain instances. We found that NNSA did not let new contracts or task orders for the DoD WFO technical projects we reviewed and instead managed them under its existing internal control process as part of its management and operating contract structure. In one instance, we noted that the Department had, at DoD's request, supplemented its control structure to incorporate specific DoD procurement requirements. Senior Department of Energy procurement officials acknowledged that neither the Department nor NNSA modified their existing prime contracts to incorporate specific defense procurement requirements because such modifications would be inappropriate, costly, and inefficient. In short, they informed us that the Department had developed and implemented a series of controls designed to monitor overall contractor performance, including WFO technical projects. Department and NNSA officials noted, however, that they were willing to incorporate DoD specific requirements into work orders should DoD request and fund such efforts. Additional details regarding management of WFO technical projects are discussed in the body of this report.« less

78 FR 14361 - Proposal Review; Notice of Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-05

... awards. The review and evaluation may also include assessment of the progress of awarded proposals. The... confidential nature, including technical information; financial data, such as salaries; and personal...

78 FR 54686 - Proposal Review; Notice of Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... awards. The review and evaluation may also include assessment of the progress of awarded proposals. The... confidential nature, including technical information; financial data, such as salaries; and personal...

Panel Resource Management (PRM) Implementation and Effects within Safety Review Panel Settings and Dynamics

NASA Technical Reports Server (NTRS)

Taylor, Robert W.; Nash, Sally K.

2007-01-01

While technical training and advanced degree's assure proficiency at specific tasks within engineering disciplines, they fail to address the potential for communication breakdown and decision making errors familiar to multicultural environments where language barriers, intimidating personalities and interdisciplinary misconceptions exist. In an effort to minimize these pitfalls to effective panel review, NASA's lead safety engineers to the ISS Safety Review Panel (SRP), and Payload Safety Review Panel (PSRP) initiated training with their engineers, in conjunction with the panel chairs, and began a Panel Resource Management (PRM) program. The intent of this program focuses on the ability to reduce the barriers inhibiting effective participation from all panel attendees by bolstering participants confidence levels through increased communication skills, situational awareness, debriefing, and a better technical understanding of requirements and systems.

A Qualitative Assessment of Current CCF Guidance Based on a Review of Safety System Digital Implementation Changes with Evolving Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Korsah, Kofi; Muhlheim, Michael David; Wood, Richard

The US Nuclear Regulatory Commission (NRC) is initiating a new rulemaking project to develop a digital system common-cause failure (CCF) rule. This rulemaking will review and modify or affirm the NRC's current digital system CCF policy as discussed in the Staff Requirements Memorandum to the Secretary of the Commission, Office of the NRC (SECY) 93-087, Policy, Technical, and Licensing Issues Pertaining to Evolutionary and Advanced Light Water Reactor (ALWR) Designs, and Branch Technical Position (BTP) 7-19, Guidance on Evaluation of Defense-in-Depth and Diversity in Digital Computer-Based Instrumentation and Control Systems, as well as Chapter 7, Instrumentation and Controls, in NRCmore » Regulatory Guide (NUREG)-0800, Standard Review Plan for Review of Safety Analysis Reports for Nuclear Power Plants (ML033580677). The Oak Ridge National Laboratory (ORNL) is providing technical support to the NRC staff on the CCF rulemaking, and this report is one of several providing the technical basis to inform NRC staff members. For the task described in this report, ORNL examined instrumentation and controls (I&C) technology implementations in nuclear power plants in the light of current CCF guidance. The intent was to assess whether the current position on CCF is adequate given the evolutions in digital safety system implementations and, if gaps in the guidance were found, to provide recommendations as to how these gaps could be closed.« less

A technical report on structural evaluation of the Meade County reinforced concrete bridge.

DOT National Transportation Integrated Search

2009-01-01

This is a technical report on the first phase of the evaluation of the Meade County reinforced concrete bridge. : The first three chapters introduce the main problem and provide a general review of the existing evaluation : methods and the procedures...

7 CFR 3400.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the grant application and approved by the Director who is responsible for the scientific and technical... instruments has been delegated. (j) Peer review group means an assembled group of experts or consultants qualified by training and experience in particular scientific or technical fields to give expert advice, in...

7 CFR 3400.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the grant application and approved by the Director who is responsible for the scientific and technical... instruments has been delegated. (j) Peer review group means an assembled group of experts or consultants qualified by training and experience in particular scientific or technical fields to give expert advice, in...

7 CFR 3400.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the grant application and approved by the Director who is responsible for the scientific and technical... instruments has been delegated. (j) Peer review group means an assembled group of experts or consultants qualified by training and experience in particular scientific or technical fields to give expert advice, in...

HANDBOOK: GUIDE TO TECHNICAL RESOURCES FOR THE DESIGN OF LAND DISPOSAL FACILITIES

EPA Science Inventory

This Handbook facilitates the preparation and processing of land disposal permit applications. It directs the regulated community and the regulators to the appropriate EPA technical resource documents, as they prepare or review permits required under PL 480 (RCRA). Topics discuss...

75 FR 41421 - Notification of Completeness of the Department of Energy's Compliance Recertification Application...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-16

... (CRA or ``application'') for the Waste Isolation Pilot Plant (WIPP) is complete. EPA provided written... disposal regulations. EPA is now engaged in the full technical review that will determine if WIPP remains... technical difficulties and cannot contact [[Page 41422

Technical aspects of neurostimulation: Focus on equipment, electric field modeling, and stimulation protocols.

PubMed

Klooster, D C W; de Louw, A J A; Aldenkamp, A P; Besseling, R M H; Mestrom, R M C; Carrette, S; Zinger, S; Bergmans, J W M; Mess, W H; Vonck, K; Carrette, E; Breuer, L E M; Bernas, A; Tijhuis, A G; Boon, P

2016-06-01

Neuromodulation is a field of science, medicine, and bioengineering that encompasses implantable and non-implantable technologies for the purpose of improving quality of life and functioning of humans. Brain neuromodulation involves different neurostimulation techniques: transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), vagus nerve stimulation (VNS), and deep brain stimulation (DBS), which are being used both to study their effects on cognitive brain functions and to treat neuropsychiatric disorders. The mechanisms of action of neurostimulation remain incompletely understood. Insight into the technical basis of neurostimulation might be a first step towards a more profound understanding of these mechanisms, which might lead to improved clinical outcome and therapeutic potential. This review provides an overview of the technical basis of neurostimulation focusing on the equipment, the present understanding of induced electric fields, and the stimulation protocols. The review is written from a technical perspective aimed at supporting the use of neurostimulation in clinical practice. Copyright © 2016 Elsevier Ltd. All rights reserved.

U.S. EPA. 2000. Science Policy Council Handbook: Peer Review

EPA Pesticide Factsheets

The goal of the Peer Review Policy and this Handbook is to enhance the quality and credibility of Agency decisions by ensuring that the scientific and technical work products underlying these decisions receive appropriate levels of peer review by independe

Development of a behavioural marker system for scrub practitioners' non-technical skills (SPLINTS system).

PubMed

Mitchell, Lucy; Flin, Rhona; Yule, Steven; Mitchell, Janet; Coutts, Kathy; Youngson, George

2013-04-01

Adverse events still occur despite ongoing efforts to reduce harm to patients. Contributory factors to adverse events are often due to limitations in clinicians' non-technical skills (e.g. communication, situation awareness), rather than deficiencies in technical competence. We developed a behavioural rating system to provide a structured means for teaching and assessing scrub practitioners' (i.e. nurse, technician, operating department practitioner) non-technical skills. Psychologists facilitated focus groups (n = 4) with experienced scrub practitioners (n = 16; 4 in each group) to develop a preliminary taxonomy. Focus groups reviewed lists of non-technical-skill-related behaviours that were extracted from an interview study. The focus groups labelled skill categories and elements and also provided examples of good and poor behaviours for those skills. An expert panel (n = 2 psychologists; n = 1 expert nurse) then used an iterative process to individually and collaboratively review and refine those data to produce a prototype skills taxonomy. A preliminary taxonomy containing eight non-technical skill categories with 28 underlying elements was produced. The expert panel reduced this to three categories (situation awareness, communication and teamwork, task management), each with three underlying elements. The system was called the Scrub Practitioners' List of Intraoperative Non-Technical Skills system. A scoring system and a user handbook were also developed. A prototype behavioural rating system for scrub practitioners' non-technical skills was developed, to aid in teaching and providing formative assessment. This important aspect of performance is not currently explicitly addressed in any educational route to qualify as a scrub practitioner. © 2012 Blackwell Publishing Ltd.

DOE Advanced Scientific Computing Advisory Committee (ASCAC) Report: Exascale Computing Initiative Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reed, Daniel; Berzins, Martin; Pennington, Robert

On November 19, 2014, the Advanced Scientific Computing Advisory Committee (ASCAC) was charged with reviewing the Department of Energy’s conceptual design for the Exascale Computing Initiative (ECI). In particular, this included assessing whether there are significant gaps in the ECI plan or areas that need to be given priority or extra management attention. Given the breadth and depth of previous reviews of the technical challenges inherent in exascale system design and deployment, the subcommittee focused its assessment on organizational and management issues, considering technical issues only as they informed organizational or management priorities and structures. This report presents the observationsmore » and recommendations of the subcommittee.« less

Technical complications of implant-causes and management: A comprehensive review

PubMed Central

Gupta, Swati; Gupta, Hemant; Tandan, Amrit

2015-01-01

Given the increasing popularity of dental implants, the number of failures due to late implant fracture is also expected to increase. Hence, the scope for prevention and management needs to be emphasized. The objective of this review article is to analyze the various causes of failure of dental implants due to implant fixture/abutment screw fractures and also to enumerate the management and the preventive options for these failures, thereby aiming to help the clinicians to properly plan the implant-supported prosthesis treatment by considering the important biomechanical aspects of this type of rehabilitation. The present review emphasizes the causes and management of technical complications and not the incidence of such complications. PMID:26668445

Image formation in diffusion MRI: A review of recent technical developments

PubMed Central

Miller, Karla L.

2017-01-01

Diffusion magnetic resonance imaging (MRI) is a standard imaging tool in clinical neurology, and is becoming increasingly important for neuroscience studies due to its ability to depict complex neuroanatomy (eg, white matter connectivity). Single‐shot echo‐planar imaging is currently the predominant formation method for diffusion MRI, but suffers from blurring, distortion, and low spatial resolution. A number of methods have been proposed to address these limitations and improve diffusion MRI acquisition. Here, the recent technical developments for image formation in diffusion MRI are reviewed. We discuss three areas of advance in diffusion MRI: improving image fidelity, accelerating acquisition, and increasing the signal‐to‐noise ratio. Level of Evidence: 5 Technical Efficacy: Stage 1 J. MAGN. RESON. IMAGING 2017;46:646–662 PMID:28194821

Liver CT image processing: a short introduction of the technical elements.

PubMed

Masutani, Y; Uozumi, K; Akahane, Masaaki; Ohtomo, Kuni

2006-05-01

In this paper, we describe the technical aspects of image analysis for liver diagnosis and treatment, including the state-of-the-art of liver image analysis and its applications. After discussion on modalities for liver image analysis, various technical elements for liver image analysis such as registration, segmentation, modeling, and computer-assisted detection are covered with examples performed with clinical data sets. Perspective in the imaging technologies is also reviewed and discussed.

NDA Batch 2002-13

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hollister, R

QC sample results (daily background check drum and 100-gram SGS check drum) were within acceptance criteria established by WIPP's Quality Assurance Objectives for TRU Waste Characterization. Replicate runs were performed on drum LL85501243TRU. Replicate measurement results are identical at the 95% confidence level as established by WIPP criteria. HWM NCAR No. 02-1000168 issued on 17-Oct-2002 regarding a partially dislodged Cd sheet filter on the HPGe coaxial detector. This physical geometry occurred on 01-Oct-2002 and was not corrected until 10-Oct-2002, during which period is inclusive of the present batch run of drums. Per discussions among the Independent Technical Reviewer, Expert Reviewermore » and the Technical QA Supervisor, as well as in consultation with John Fleissner, Technical Point of Contact from Canberra, the analytical results are technically reliable. All QC standard runs during this period were in control. Data packet for SGS Batch 2002-13 generated using passive gamma-ray spectroscopy with the Pu Facility SGS unit is technically reasonable. All QC samples are in compliance with establiShed control limits. The batch data packet has been reviewed for correctness, completeness, consistency and compliance with WIPP's Quality Assurance Objectives and determined to be acceptable.« less

Book Review: New Perspectives on Technical Editing

NASA Astrophysics Data System (ADS)

Murphy, A. J. (Ed.); Sterken, Christiaan

2012-08-01

New Perspectives on Technical Editing by Avon J. Murphy (ed.) ISBN : 978-0895033949 (2010) Baywood Publishing Company Inc, Hardcover, 210 pages, 35.5 GBP This book presents a collection of 10 chapters dealing with diverse aspects of technical editing (ie, editorial planning, and analysis and structural changes made to other people's technological documents): research in technical editing, trends and teaching of technical editing, copyediting, and technical journal editing. The role and function of the modern journal and book editor is also dealt with in detail. Each chapter is written by an expert in the field: senior editors, university professors in technical communication, technical writers and linguists. The ever-evolving role of the editor is clearly elucidated in several historical reviews, and in the descriptions of the expectations for the future. A very striking aspect of this book is its extensive collection of bibliographic resources: every chapter lists dozens of very useful references, and the closing chapter, and annotated bibliography, contain many not so well known references, and are most useful. All in all, the book is a treasure trove listing more than 400 references, in addition to numerous webpage URLs embedded in the texts. The book is designed to help the reader to understand current practices and norms in technical editing, and to help to take action in editing as well as in teaching and educating would-be editors. The audience for this book thus includes editors and teachers, but also writers, researchers and students. A deep reading of this book will result in a better understanding of the difference between full technical editing and its much narrower component so well known as copyediting, and will convince any prospective editor that editing should not be undertaken if the people involved do not master the art of precision and accuracy in technical (as well as in human) communication, do not possess the technical know how and computer skills, or do not have a very broad knowledge base. The language fluency of every contributor makes this book a pleasure to read, and this particular volume of Baywood's Technical Communications Series is very well edited. The subject index covers almost 8 two-column pages.

Teaching Leadership in Technical Programs at Community Colleges

ERIC Educational Resources Information Center

DeBlauw, Amanda L.; Daugherty, Jenny L.

2017-01-01

This descriptive study explored how community colleges are teaching leadership in technical programs. Leadership education curricular offerings were identified via a survey and selected programs reviewed. 68 Deans, Directors, or Chairpersons of a Business, Management, or Technology program completed the survey, representing 61 community colleges.…

EPA OFFICE OF RESEARCH AND DEVELOPMENT GUIDELINES FOR TECHNICAL EVALUATION OF ECOLOGICAL INDICATORS

EPA Science Inventory

EPA's Office of Research and Development (ORD) has prepared fifteen technical guidelines to evaluate the suitability of an ecological indicator in a monitoring program. The guidelines were fashioned to provide a consistent framework for indicator review and to provide direction f...

Technical Writing Needs Assessment.

ERIC Educational Resources Information Center

Oakland Community Coll., Farmington, MI. Office of Institutional Planning and Analysis.

In fall 1991, a study was conducted by Oakland Community College (OCC) to evaluate the need for a proposed Technical Writing program. General information was gathered from a literature review, Michigan Occupational Information System data, interviews with professionals in the field, and a 1987 needs assessment conducted by Washtenaw Community…

Occupational-Technical Curriculum Development TV Study.

ERIC Educational Resources Information Center

McClure, Lyndon

Section I of this report provides a brief review of various experiments and studies conducted in the United States and abroad on the effectiveness of televised occupational-technical courses. Issues discussed include the packaging of televised instruction; the need for preproduction testing; the limitations of television teaching; teacher and…

A Goal Programming/Constrained Regression Review of the Bell System Breakup.

DTIC Science & Technology

1985-05-01

characteristically employ. 4 .- - -. . ,. - - ;--.. . . .. 2. MULTI-PRODUCT COST MODEL AND DATA DETAILS When technical efficiency (i.e. zero waste ) can be assumed...assumming, but we believe that it was probably technical (= zero waste ) efficiency by virtue of the following reasons. Scale efficien- cy was a

Our built and natural environments : a technical review of the interactions between land use, transportation, and environmental quality

DOT National Transportation Integrated Search

2001-01-01

In recent years interest has grown in Smart Growth as a mechanism for improving environmental quality. In Our Built and Natural Environments, the U.S. Environmental Protection Agency (EPA) summarizes technical research on the relationship between the...

HRD and Small Manufacturers. Symposium 42. [AHRD Conference, 2001].

ERIC Educational Resources Information Center

2001

This symposium on human resource development (HRD) and small manufacturers consists of three presentations. "Toward a Model of Technical Assistance for Small Manufacturers: The Role of Performance Technology" (Dale C. Brandenburg) reviews literature documenting the need for technical assistance to small manufacturers, especially as it…

7 CFR 1709.123 - Evaluation criteria and weights.

Code of Federal Regulations, 2010 CFR

2010-01-01

... design and technical merit criteria shall not be less than 65 percent of the total available points, and... announcement. (b) Project design and technical merit. In reviewing the grant proposal's project design and... the proposed design, construction, equipment and materials for the proposed energy facilities to...

29 CFR 1990.106 - Amendments to this policy.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., to review this part and render their opinions on whether significant scientific or technical advances... believes that scientific or technical advances justify such amendments. (3) Petitions from the public. (i... petitioner believes are inappropriate; (C) All data, views and arguments relied upon by the petitioner; and...

29 CFR 1990.106 - Amendments to this policy.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., to review this part and render their opinions on whether significant scientific or technical advances... believes that scientific or technical advances justify such amendments. (3) Petitions from the public. (i... petitioner believes are inappropriate; (C) All data, views and arguments relied upon by the petitioner; and...

29 CFR 1990.106 - Amendments to this policy.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., to review this part and render their opinions on whether significant scientific or technical advances... believes that scientific or technical advances justify such amendments. (3) Petitions from the public. (i... petitioner believes are inappropriate; (C) All data, views and arguments relied upon by the petitioner; and...

29 CFR 1990.106 - Amendments to this policy.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., to review this part and render their opinions on whether significant scientific or technical advances... believes that scientific or technical advances justify such amendments. (3) Petitions from the public. (i... petitioner believes are inappropriate; (C) All data, views and arguments relied upon by the petitioner; and...

29 CFR 1990.106 - Amendments to this policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., to review this part and render their opinions on whether significant scientific or technical advances... believes that scientific or technical advances justify such amendments. (3) Petitions from the public. (i... part. [45 FR 5282, Jan. 22, 1980; 45 FR 43405, June 27, 1980] The OSHA Cancer Policy ...

Technological Innovations in Magnetic Resonance for Early Detection of Cardiovascular Diseases.

PubMed

Santarelli, Maria F; Positano, Vincenzo; Martini, Nicola; Valvano, Giuseppe; Landini, Luigi

2016-01-01

Most recent technical innovations in cardiovascular MR imaging (CMRI) are presented in this review. They include hardware and software developments, and novelties in parametric mapping. All these recent improvements lead to high spatial and temporal resolution and quantitative information on the heart structure and function. They make it achievable ambitious goals in the field of magnetic resonance, such as the early detection of cardiovascular pathologies. In this review article, we present recent innovations in CMRI, emphasizing the progresses performed and the solutions proposed to some yet opened technical problems.

Quarterly literature review of the remote sensing of natural resources

NASA Technical Reports Server (NTRS)

Fears, C. B. (Editor); Inglis, M. H. (Editor)

1977-01-01

The Technology Application Center reviewed abstracted literature sources, and selected document data and data gathering techniques which were performed or obtained remotely from space, aircraft or groundbased stations. All of the documentation was related to remote sensing sensors or the remote sensing of the natural resources. Sensors were primarily those operating within the 10 to the minus 8 power to 1 meter wavelength band. Included are NASA Tech Briefs, ARAC Industrial Applications Reports, U.S. Navy Technical Reports, U.S. Patent reports, and other technical articles and reports.

DOE Advanced Scientific Computing Advisory Committee (ASCAC) Subcommittee Report on Scientific and Technical Information

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hey, Tony; Agarwal, Deborah; Borgman, Christine

The Advanced Scientific Computing Advisory Committee (ASCAC) was charged to form a standing subcommittee to review the Department of Energy’s Office of Scientific and Technical Information (OSTI) and to begin by assessing the quality and effectiveness of OSTI’s recent and current products and services and to comment on its mission and future directions in the rapidly changing environment for scientific publication and data. The Committee met with OSTI staff and reviewed available products, services and other materials. This report summaries their initial findings and recommendations.

1999 NASA High-Speed Research Program Aerodynamic Performance Workshop. Volume 2; High Lift

NASA Technical Reports Server (NTRS)

Hahne, David E. (Editor)

1999-01-01

The High-Speed Research Program sponsored the NASA High-Speed Research Program Aerodynamic Performance Review on February 8-12, 1999 in Anaheim, California. The review was designed to bring together NASA and industry High-Speed Civil Transport (HSCT) Aerodynamic Performance technology development participants in areas of: Configuration Aerodynamics (transonic and supersonic cruise drag prediction and minimization) and High-Lift. The review objectives were to: (1) report the progress and status of HSCT aerodynamic performance technology development; (2) disseminate this technology within the appropriate technical communities; and (3) promote synergy among the scientist and engineers working HSCT aerodynamics. The HSR AP Technical Review was held simultaneously with the annual review of the following airframe technology areas: Materials and Structures, Environmental Impact, Flight Deck, and Technology Integration Thus, a fourth objective of the Review was to promote synergy between the Aerodynamic Performance technology area and the other technology areas within the airframe element of the HSR Program. This Volume 2/Part 1 publication presents the High-Lift Configuration Development session.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, Antoniette J

Los Alamos National Laboratory (LANL) uses external peer review to measure and continuously improve the quality of its science, technology and engineering (STE). LANL uses capability reviews to assess the STE quality and institutional integration and to advise Laboratory Management on the current and future health of the STE. Capability reviews address the STE integration that LANL uses to meet mission requirements. STE capabilities are define to cut across directorates providing a more holistic view of the STE quality, integration to achieve mission requirements, and mission relevance. The scope of these capabilities necessitate that there will be significant overlap inmore » technical areas covered by capability reviews (e.g ., materials research and weapons science and engineering). In addition, LANL staff may be reviewed in different capability reviews because of their varied assignments and expertise. LANL plans to perform a complete review of the Laboratory's STE capabilities (hence staff) in a three-year cycle. The principal product of an external review is a report that includes the review committee's assessments, commendations, and recommendations for STE. The Capability Review Committees serve a dual role of providing assessment of the Laboratory's technical contributions and integration towards its missions and providing advice to Laboratory Management. The assessments and advice are documented in reports prepared by the Capability Review Committees that are delivered to the Director and to the Principal Associate Director for Science, Technology and Engineering (PADSTE). This report will be used by Laboratory Management for STE assessment and planning. The report is also provided to the Department of Energy (DOE) as part of LANL's Annual Performance Plan and to the Los Alamos National Security (LANS) LLC's Science and Technology Committee (STC) as part of its responsibilities to the LANS Board of Governors. LANL has defined fourteen STE capabilities. Table 1 lists the five STE capabilities that LANL Management (Director, PADSTE, technical Associate Directors) have identified for review in Fiscal Year (FY) 2009.« less

The Independent Technical Analysis Process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duberstein, Corey A.; Ham, Kenneth D.; Dauble, Dennis D.

2007-04-13

The Bonneville Power Administration (BPA) contracted with the Pacific Northwest National Laboratory (PNNL) to provide technical analytical support for system-wide fish passage information (BPA Project No. 2006-010-00). The goal of this project was to produce rigorous technical analysis products using independent analysts and anonymous peer reviewers. In the past, regional parties have interacted with a single entity, the Fish Passage Center to access the data, analyses, and coordination related to fish passage. This project provided an independent technical source for non-routine fish passage analyses while allowing routine support functions to be performed by other well-qualified entities.

International Approaches for Nuclear Waste Disposal in Geological Formations: Report on Fifth Worldwide Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faybishenko, Boris; Birkholzer, Jens; Persoff, Peter

2016-09-01

The goal of the Fifth Worldwide Review is to document evolution in the state-of-the-art of approaches for nuclear waste disposal in geological formations since the Fourth Worldwide Review that was released in 2006. The last ten years since the previous Worldwide Review has seen major developments in a number of nations throughout the world pursuing geological disposal programs, both in preparing and reviewing safety cases for the operational and long-term safety of proposed and operating repositories. The countries that are approaching implementation of geological disposal will increasingly focus on the feasibility of safely constructing and operating their repositories in short-more » and long terms on the basis existing regulations. The WWR-5 will also address a number of specific technical issues in safety case development along with the interplay among stakeholder concerns, technical feasibility, engineering design issues, and operational and post-closure safety. Preparation and publication of the Fifth Worldwide Review on nuclear waste disposal facilitates assessing the lessons learned and developing future cooperation between the countries. The Report provides scientific and technical experiences on preparing for and developing scientific and technical bases for nuclear waste disposal in deep geologic repositories in terms of requirements, societal expectations and the adequacy of cases for long-term repository safety. The Chapters include potential issues that may arise as repository programs mature, and identify techniques that demonstrate the safety cases and aid in promoting and gaining societal confidence. The report will also be used to exchange experience with other fields of industry and technology, in which concepts similar to the design and safety cases are applied, as well to facilitate the public perception and understanding of the safety of the disposal approaches relative to risks that may increase over long times frames in the absence of a successful implementation of final dispositioning.« less

77 FR 72334 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-05

.... Title, Form, and OMB Number: Militarily Critical Technical Data Agreement, DD Form 2354; OMB Control... unclassified DoD-controlled militarily critical technical data must certify on DD Form 2345, Militarily... requirements and is so indicated on the Privacy Act Statement of DD Form 2345. Affected Public: Individuals or...

Risk assessments for mixtures: technical methods commonly used in the United States

EPA Science Inventory

A brief (20 minute) talk on the technical approaches used by EPA and other US agencies to assess risks posed by combined exposures to one or more chemicals. The talk systemically reviews the methodologies (whole-mixtures and component-based approaches) that are or have been used ...

A Vowel-Based Method for Vocal Tract Control in Clarinet Pedagogy

ERIC Educational Resources Information Center

González, Darleny; Payri, Blas

2017-01-01

Our review of scientific literature shows that the activity inside the clarinetist's vocal tract (VT) affects pitch and timbre, while also facilitating technical exercises. Clarinetists adapt their VT intuitively and, in some cases, may compensate an inadequate VT configuration through unnecessary pressure, resulting in technical blockage,…

40 CFR 35.1640-1 - Application review criteria.

Code of Federal Regulations, 2010 CFR

2010-07-01

... information supplied by the applicant which address the following criteria: (1) The technical feasibility of...) of the Act. (6) The reasonableness of the proposed costs relative to the proposed work, the... presented in paragraph (a) of this section will be modified in relation to the smaller amount of technical...

U.S. EPA OFFICE OF RESEARCH AND DEVELOPMENT GUIDELINES FOR TECHNICAL EVALUATION OF ECOLOGICAL INDICATORS

EPA Science Inventory

EPA's Office of Research and Development (ORD) has prepared fifteen technical guidelines to evaluate the suitability of an ecological indicator in a monitoring program. The guidelines were fashioned to provide a consistent framework for indicator review and to provide direction f...

78 FR 70040 - Draft Integrated Science Assessment for Nitrogen Oxides-Health Criteria

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-22

... (NO 2 ). The Integrated Science Assessment (ISA), in conjunction with additional technical and policy... the secondary (welfare-based) NAAQS for NO 2 , in conjunction with a review of the secondary NAAQS for... called an Air Quality Criteria Document). The ISA, in conjunction with additional technical and policy...

Using a Collaborative Critiquing Technique to Develop Chemistry Students' Technical Writing Skills

ERIC Educational Resources Information Center

Carr, Jeremy M.

2013-01-01

The technique, termed "collaborative critiquing", was developed to teach fundamental technical writing skills to analytical chemistry students for the preparation of laboratory reports. This exercise, which can be completed prior to peer-review activities, is novel, highly interactive, and allows students to take responsibility for their…

The decay of NASA's technical culture

NASA Technical Reports Server (NTRS)

Mccurdy, Howard E.

1989-01-01

Changes in the organization structure and technical research activities of NASA since 1970 are evaluated. The creation of NASA and the original organizational structure and operation of NASA are reviewed. The relationship between organization and advanced technology is discussed and suggestions are given for ways of maintaining NASA as a high reliability organization.

(Review Draft) Radiation Site Cleanup Regulations: Technical Support Document For The Development Of Radionuclide Cleanup Levels For Soil

EPA Pesticide Factsheets

This document describes parts of the technical analysis being undertaken in support of standards that ensure certain sites are cleaned up to a level that is protective of human health and the environment before they are released for public use.

State Leadership for Career Technical Education.

ERIC Educational Resources Information Center

Kister, Joanna

This document is comprised of two main parts: (1) Role and Nature of State Leadership; and (2) Developing Leaders. Issues related to state leadership for career and technical education (CTE) were studied. CTE-related research, policy, and practice were reviewed. State directors of CTE were surveyed, and 39 individuals considered opinion leaders in…

Case Studies in Industry/TAFE Liaison: Success Factors.

ERIC Educational Resources Information Center

Anderson, Tony

This study examines what makes cooperative arrangements between industry and Technical and Further Education (TAFE) in Australia successful. A literature review highlighted the importance of the provision of high quality technical education that meets the needs of the client. A range of innovative or entrepreneurial examples of industry/TAFE…

Technical Information Resource on Rare Earth Elements Now Available to Public and Private Sector Stakeholders

EPA Science Inventory

A new EPA technical information resource, “Rare Earth Elements: A Review of Production, Processing, Recycling, and Associated Environmental Issues” has been produced as an introductory resource for those interested in learning more about REE mining and alternatives to meet demand...

77 FR 24587 - Addition of Certain Persons to the Entity List; and Implementation of Entity List Annual Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-25

...; --Mahtab Technical Engineering Company; --Composite Propellant Missile Industry; and --Sanaye Sokhte... entity; 0 (i) By removing the ``Country'' column for South Korea, including the South Korean entity... Technical Engineering Company;. --Composite Propellant Missile Industry; and. --Sanaye Sokhte Morakab (SSM...

77 FR 22285 - Fisheries of the South Atlantic; South Atlantic Fishery Management Council; Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-13

... the South Atlantic; South Atlantic Fishery Management Council; Public Meeting AGENCY: National Marine... of a public meeting of the South Atlantic Fishery Management Council's Technical Shrimp Review Panel. SUMMARY: The South Atlantic Fishery Management Council (SAFMC) will hold a meeting of its Technical Shrimp...

Space lab system analysis: Advanced Solid Rocket Motor (ASRM) communications networks analysis

NASA Technical Reports Server (NTRS)

Ingels, Frank M.; Moorhead, Robert J., II; Moorhead, Jane N.; Shearin, C. Mark; Thompson, Dale R.

1990-01-01

A synopsis of research on computer viruses and computer security is presented. A review of seven technical meetings attended is compiled. A technical discussion on the communication plans for the ASRM facility is presented, with a brief tutorial on the potential local area network media and protocols.

77 FR 28393 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-14

... Support Post Earthquake Reconstruction, Cholera and HIV/AIDS Response, FOA GH12-001, and Research and Technical Assistance for Public Health Laboratories in Haiti to Support Post Earthquake Reconstruction... and Technical Assistance for Public Health Interventions in Haiti to Support Post Earthquake...

The Library Work Order Processing System: A New Approach to Motivate Employees and to Increase Production in the Technical Service Department of Mercer County Community College Library. Applied Educational Research and Evaluation.

ERIC Educational Resources Information Center

Sim, Yong Sup

After reviewing the current movement toward job enrichment, a system was designed for the technical services department of the Mercer County Community College Library. The Library Work Order Processing System, as tried between January and March, 1974, was designed to permit each worker more variety of jobs. The technical services department was…

Book Review: Bioassays with Arthropods: 2nd Edition

USDA-ARS?s Scientific Manuscript database

The technical book "Bioassays with Arthropods: 2nd Edition" (2007. Jacqueline L. Robertson, Robert M. Russell, Haiganoush K, Preisler and N. E. Nevin, Eds. CRC Press, Boca Raton, FL, 224 pp.) was reviewed for the scientific readership of the peer-reviewed publication Journal of Economic Entomology. ...

The Future Cybersecurity Workforce: Going Beyond Technical Skills for Successful Cyber Performance.

PubMed

Dawson, Jessica; Thomson, Robert

2018-01-01

One of the challenges in writing an article reviewing the current state of cyber education and workforce development is that there is a paucity of quantitative assessment regarding the cognitive aptitudes, work roles, or team organization required by cybersecurity professionals to be successful. In this review, we argue that the people who operate within the cyber domain need a combination of technical skills, domain specific knowledge, and social intelligence to be successful. They, like the networks they operate, must also be reliable, trustworthy, and resilient. Defining the knowledge, skills, attributes, and other characteristics is not as simple as defining a group of technical skills that people can be trained on; the complexity of the cyber domain makes this a unique challenge. There has been little research devoted to exactly what attributes individuals in the cyber domain need. What research does exist places an emphasis on technical and engineering skills while discounting the important social and organizational influences that dictate success or failure in everyday settings. This paper reviews the literature on cyber expertise and cyber workforce development to identify gaps and then argues for the important contribution of social fit in the highly complex and heterogenous cyber workforce. We then identify six assumptions for the future of cybersecurity workforce development, including the requirement for systemic thinkers, team players, a love for continued learning, strong communication ability, a sense of civic duty, and a blend of technical and social skill. Finally, we make recommendations for social and cognitive metrics which may be indicative of future performance in cyber work roles to provide a roadmap for future scholars.

2012 DOE Vehicle Technologies Program Annual Merit Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

The 2012 DOE Hydrogen Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting was held May 14-18, 2012 in Crystal City, Virginia. The review encompassed all of the work done by the Hydrogen Program and the Vehicle Technologies Program: a total of 309 individual activities were reviewed for Vehicle Technologies, by a total of 189 reviewers. A total of 1,473 individual review responses were received for the technical reviews.

Updated Multistate Review of Professional Teaching Standards. REL Technical Brief. REL 2010-No. 014

ERIC Educational Resources Information Center

White, Melissa Eiler; Makkonen, Reino; Stewart, Kari Becker

2010-01-01

This review of teaching standards in six states updates a 2009 review (White, Makkonen, and Stewart 2009) by incorporating California's recently adopted teaching standards alongside those from Florida, Illinois, North Carolina, Ohio, and Texas. The previous review was developed at the request of key education agencies in California to inform the…