Development of a Work Control System for Propulsion Testing at NASA Stennis

NASA Technical Reports Server (NTRS)

Messer, Elizabeth A.

2005-01-01

This paper will explain the requirements and steps taken to develop the current Propulsion Test Directorate electronic work control system for Test Operations. The PTD Work Control System includes work authorization and technical instruction documents, such as test preparation sheets, discrepancy reports, test requests, pre-test briefing reports, and other test operations supporting tools. The environment that existed in the E-Complex test areas in the late 1990's was one of enormous growth which brought people of diverse backgrounds together for the sole purpose of testing propulsion hardware. The problem that faced us was that these newly formed teams did not have a consistent and clearly understood method for writing, performing or verifying work. A paper system was developed that would allow the teams to use the same forms, but this still presented problems in the large amount of errors occurring, such as lost paperwork and inconsistent implementation. In a sampling of errors in August 1999, the paper work control system encountered 250 errors out of 230 documents released and completed, for an error rate of 111%.

14 CFR 1206.703 - Aggregation of requests.

Code of Federal Regulations, 2010 CFR

2010-01-01

... documents, solely in order to avoid payment of fees. When NASA has reason to believe that a requester or a group of requesters acting in concert, is attempting to break a request down into a series of requests...

7 CFR 1717.308 - RUS approval of nonconforming rates.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Federal Pre-emption in Rate Making in Connection With Power Supply Borrowers § 1717.308 RUS approval of... of the RUS wholesale power contract and other RUS documents if RUS determines, in its sole discretion...

7 CFR 1717.308 - RUS approval of nonconforming rates.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Federal Pre-emption in Rate Making in Connection With Power Supply Borrowers § 1717.308 RUS approval of... of the RUS wholesale power contract and other RUS documents if RUS determines, in its sole discretion...

A Screening Assessment of the Potential Impacts of Climate Change on the Costs of Implementing Water Quality-Based Effluent Limits at Publicly-Owned Treatment Works (Potws) in the Great Lakes Region (External Review Draft)

EPA Science Inventory

EPA has released this draft document solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy ...

A Screening Assessment of the Potential Impacts of Climate ...

EPA Pesticide Factsheets

EPA has released this draft document solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination. EPA will consider any public comments submitted in accordance with this notice when revising the document. The report is a screening level analysis intended to determine the scope and magnitude of global change impacts rather than a detailed assessment of specific impacts and adaptation measures.

C-TIC Console Operator's User Manual

DOT National Transportation Integrated Search

1996-07-01

The C-TIC Console Operator's User Manual is designed to assist the operator at : the Corridor Transportation Information Center with the navigation and use of : the application programs in the C-TIC. This document will concentrate solely on : the ext...

5 CFR 9701.508 - Homeland Security Labor Relations Board.

Code of Federal Regulations, 2010 CFR

2010-01-01

... appoint the member for an additional term. The Secretary, in his or her sole and exclusive discretion, may... the HSLRB consists of an odd number of members. (2) Members of the HSLRB must be independent..., at his or her sole and exclusive discretion, will appoint one member to serve as Chair of the HSLRB...

75 FR 5317 - Exposure Factors Handbook: 2009 Update

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-02

... chemicals. These factors include: Drinking water consumption; mouthing behavior; soil ingestion rates... document solely for the purpose of pre- dissemination peer review under applicable information quality... various factors used in assessing human exposure. This Handbook is aimed at exposure assessors inside the...

Retrospective analysis of Bering Sea bottom trawl surveys: regime shift and ecosystem reorganization

NASA Astrophysics Data System (ADS)

Conners, M. E.; Hollowed, A. B.; Brown, E.

2002-10-01

This paper compiles data from bottom trawl surveys using variations on a 400-mesh eastern trawl gear into a 38-year time series (1963-2000), using a robust index of median catch per unit effort (CPUE) as an indicator of regional abundance. Time series are presented for three index sites in the southeastern Bering Sea: the inner shelf in Bristol Bay, the middle shelf north of Unimak Island, and the outer shelf near the Pribilof Islands. All three sites show strong evidence of a shift in benthic biomass and community structure in the early to mid-1980s. During this period, all three sites showed substantial increases in the abundances of walleye pollock, Pacific cod, rock sole, flathead sole, cartilaginous fishes (skates) and non-crab benthic invertebrates. Species composition, especially of flatfish, differs at the three sites, but the trend for groundfish abundance to increase was consistent at all three sites. The similarity in trends both across the region and across both commercial and unexploited groups suggests to us that a complete reorganization of benthic and demersal food webs may have taken place. The timing of change in trawl catch weight is consistent with effects of the strong regime shift observed in climate indices in 1976-1977. There is little evidence of similar biological responses to subsequent, less pronounced changes in climate. Our data are also consistent with recently documented shifts in ecosystem dynamics resulting from changes in ice cover and thermal structure in the eastern Bering Sea. Our analysis indicates that there was a much higher biomass of groundfish at all three sites during 1980-2000 than in 1960-1980. This result provides evidence against the hypothesis that the overall productivity of the eastern Bering Sea has decreased. The precipitous decline of the endangered Steller sea lion in this region from 1975-1985 was concurrent with an overall increase in abundance of groundfish prey.

Extended documentation for hand dermatitis patients: Pilot study on irritant exposures.

PubMed

Uter, Wolfgang; Bauer, Andrea; Bensefa-Colas, Lynda; Brans, Richard; Crépy, Marie-Noëlle; Giménez-Arnau, Ana; Larese Filon, Francesca; Ljubojević Hadžavdić, Suzana; Pesonen, Maria; Schuttelaar, Marie L; Wilkinson, Mark; Lidén, Carola

2018-05-30

Irritant exposure may be a contributory cause or the sole cause of (occupational) hand dermatitis. However, the documentation of irritant exposures in clinical practice is not standardized. To examine the feasibility and usefulness of a form with different items addressing both occupational and non-occupational irritant exposures in a semiquantitative way. Between May 2016 and May 2017, successive patients with work-related hand dermatitis, irrespective of aetiology, were examined in 9 specialized European departments. Department-specific investigation was supplemented with the above proforma. The results were recorded by use of an anonymized secured online documentation system in a pilot study. Altogether, 193 patients were included; 114 females and 79 males, with a mean age of 40 years (range 18-68 years). The most common occupational group comprised healthcare workers (n = 35); occupational exposure of the hands to gloves, dusts and water without detergents of >2 hours/day was seen in 54.5%, 24.4% and 24.3% of patients, respectively. Non-occupational exposures rarely exceeded 2 hours/day. It is hoped that the set of descriptors will offer a basis for (clinical) epidemiological studies assessing the role of irritant exposures in occupational hand dermatitis, and to support a high level of quality and consistency in daily patient care. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Owning Corporate Texts.

ERIC Educational Resources Information Center

Winsor, Dorothy A.

1993-01-01

Examines the relationship between technical writers and their texts. Suggests the amount of ownership any writer has varies depending on context; therefore, in technical writing, the more a document represents an organization, the less likely the words and ideas are to be solely under the control of the writer. (NH)

Finance issue brief: medical necessity: year end report-2003.

PubMed

MacEachern, Lillian

2003-12-31

The information in this issue brief is based on a 50--state survey and a recent literature review. The Health Policy Tracking Service recognizes the complexity of this issue and discourages the use of this document as a sole resource on the issue.

Finance issue brief: medical necessity: year end report-2002.

PubMed

Morgan, Rachel; MacEachern, Lillian

2002-12-31

The information in this issue brief is based on a 50--state survey and a recent literature review. The Health Policy Tracking Service recognizes the complexity of this issue and discourages the use of this document as a sole resource on the issue.

Mass Casualty Decontamination Guidance and Psychosocial Aspects of CBRN Incident Management: A Review and Synthesis

PubMed Central

Carter, Holly; Amlôt, Richard

2016-01-01

Introduction: Mass casualty decontamination is an intervention employed by first responders at the scene of an incident involving noxious contaminants.  Many countries have sought to address the challenge of decontaminating large numbers of affected casualties through the provision of rapidly deployable temporary showering structures, with accompanying decontamination protocols.  In this paper we review decontamination guidance for emergency responders and associated research evidence, in order to establish to what extent psychosocial aspects of casualty management have been considered within these documents. The review focuses on five psychosocial aspects of incident management: likely public behaviour; responder management style; communication strategy; privacy/ modesty concerns; and vulnerable groups. Methods: Two structured literature reviews were carried out; one to identify decontamination guidance documents for first responders, and another to identify evidence which is relevant to the understanding of the psychosocial aspects of mass decontamination.  The guidance documents and relevant research were reviewed to identify whether the guidance documents contain information relating to psychosocial issues and where it exists, that the guidance is consistent with the existing evidence-base. Results: Psychosocial aspects of incident management receive limited attention in current decontamination guidance.  In addition, our review has identified a number of gaps and inconsistencies between guidance and research evidence.  For each of the five areas we identify: what is currently presented in guidance documents, to what extent this is consistent with the existing research evidence and where it diverges.  We present a series of evidence-based recommendations for updating decontamination guidance to address the psychosocial aspects of mass decontamination. Conclusions: Effective communication and respect for casualties’ needs are critical in ensuring decontamination is completed quickly and effectively.  We identify a number of areas requiring further research including: identifying effective methods for communicating in an emergency; better understanding of the needs of vulnerable groups during decontamination; effective training for emergency responders on psychosocial issues, and pre-incident public education for incidents involving emergency decontamination.  It is essential that the psychosocial aspects of mass decontamination are not neglected in the pursuit of solely technical solutions. PMID:27790383

77 FR 72788 - Copyright Office Fees

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... Adobe Portable Document File (PDF) format that contains searchable, accessible text (not an image... processing such statements and associated royalty payments was funded solely by the royalty fees collected... Title 17 that permits the Office to apportion up to 50 percent of the cost of processing the SOAs and...

32 CFR 1801.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) days may be added if responding by international mail; Control means ownership or the authority of... judicial branches of government, United States or foreign, or U.S. Government contractor who, in the sole discretion of NACIC, has a subject matter or physical interest in the documents or information at issue...

32 CFR 1801.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) days may be added if responding by international mail; Control means ownership or the authority of... judicial branches of government, United States or foreign, or U.S. Government contractor who, in the sole discretion of NACIC, has a subject matter or physical interest in the documents or information at issue...

32 CFR 1801.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) days may be added if responding by international mail; Control means ownership or the authority of... judicial branches of government, United States or foreign, or U.S. Government contractor who, in the sole discretion of NACIC, has a subject matter or physical interest in the documents or information at issue...

32 CFR 1801.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) days may be added if responding by international mail; Control means ownership or the authority of... judicial branches of government, United States or foreign, or U.S. Government contractor who, in the sole discretion of NACIC, has a subject matter or physical interest in the documents or information at issue...

Uav Surveying for a Complete Mapping and Documentation of Archaeological Findings. The Early Neolithic Site of Portonovo

NASA Astrophysics Data System (ADS)

Malinverni, E. S.; Conati Barbaro, C.; Pierdicca, R.; Bozzi, C. A.; Tassetti, A. N.

2016-06-01

The huge potential of 3D digital acquisition techniques for the documentation of archaeological sites, as well as the related findings, is almost well established. In spite of the variety of available techniques, a sole documentation pipeline cannot be defined a priori because of the diversity of archaeological settings. Stratigraphic archaeological excavations, for example, require a systematic, quick and low cost 3D single-surface documentation because the nature of stratigraphic archaeology compels providing documentary evidence of any excavation phase. Only within a destructive process each single excavation cannot be identified, documented and interpreted and this implies the necessity of a re- examination of the work on field. In this context, this paper describes the methodology, carried out during the last years, to 3D document the Early Neolithic site of Portonovo (Ancona, Italy) and, in particular, its latest step consisting in a photogrammetric aerial survey by means of UAV platform. It completes the previous research delivered in the same site by means of terrestrial laser scanning and close range techniques and sets out different options for further reflection in terms of site coverage, resolution and campaign cost. With the support of a topographic network and a unique reference system, the full documentation of the site is managed in order to detail each excavation phase; besides, the final output proves how the 3D digital methodology can be completely integrated with reasonable costs during the excavation and used to interpret the archaeological context. Further contribution of this work is the comparison between several acquisition techniques (i.e. terrestrial and aerial), which could be useful as decision support system for different archaeological scenarios. The main objectives of the comparison are: i) the evaluation of 3D mapping accuracy from different data sources, ii) the definition of a standard pipeline for different archaeological needs and iii) the provision of different level of detail according to the user needs.

50 CFR 222.204 - Administration of certificates.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Certificates of Exemption for Pre-Act Endangered Species Parts § 222.204 Administration of certificates. (a... warehouse facility used by the certificate holder solely for storage of pre-Act endangered species parts, if... documents and any endangered species parts. (f) The records pertaining to pre-Act endangered species parts...

50 CFR 222.204 - Administration of certificates.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Certificates of Exemption for Pre-Act Endangered Species Parts § 222.204 Administration of certificates. (a... warehouse facility used by the certificate holder solely for storage of pre-Act endangered species parts, if... documents and any endangered species parts. (f) The records pertaining to pre-Act endangered species parts...

50 CFR 222.204 - Administration of certificates.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Certificates of Exemption for Pre-Act Endangered Species Parts § 222.204 Administration of certificates. (a... warehouse facility used by the certificate holder solely for storage of pre-Act endangered species parts, if... documents and any endangered species parts. (f) The records pertaining to pre-Act endangered species parts...

50 CFR 222.204 - Administration of certificates.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Certificates of Exemption for Pre-Act Endangered Species Parts § 222.204 Administration of certificates. (a... warehouse facility used by the certificate holder solely for storage of pre-Act endangered species parts, if... documents and any endangered species parts. (f) The records pertaining to pre-Act endangered species parts...

50 CFR 222.204 - Administration of certificates.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Certificates of Exemption for Pre-Act Endangered Species Parts § 222.204 Administration of certificates. (a... warehouse facility used by the certificate holder solely for storage of pre-Act endangered species parts, if... documents and any endangered species parts. (f) The records pertaining to pre-Act endangered species parts...

21 CFR 514.8 - Supplements and other changes to an approved application.

Code of Federal Regulations, 2013 CFR

2013-04-01

... method(s) or an addition, deletion, or substitution of steps in an aseptic processing operation; (D... solely affecting a natural product, a recombinant DNA-derived protein/polypeptide, or a complex or...) or references to previously approved documentation; (H) For a natural product, a recombinant DNA...

21 CFR 514.8 - Supplements and other changes to an approved application.

Code of Federal Regulations, 2014 CFR

2014-04-01

... method(s) or an addition, deletion, or substitution of steps in an aseptic processing operation; (D... solely affecting a natural product, a recombinant DNA-derived protein/polypeptide, or a complex or...) or references to previously approved documentation; (H) For a natural product, a recombinant DNA...

21 CFR 514.8 - Supplements and other changes to an approved application.

Code of Federal Regulations, 2012 CFR

2012-04-01

... method(s) or an addition, deletion, or substitution of steps in an aseptic processing operation; (D... solely affecting a natural product, a recombinant DNA-derived protein/polypeptide, or a complex or...) or references to previously approved documentation; (H) For a natural product, a recombinant DNA...

College Choice and Documented Chinese Immigrant Community College Students in Massachusetts

ERIC Educational Resources Information Center

Luie, Siu Ming

2010-01-01

College-choice studies have long been conducted to help colleges improve their recruitment strategies (Chapman, 1981; Hossler & Gallagher, 1987; Jackson, 1982; Litten, 1982). The dominant college-choice models and studies have, however, focused solely on traditional aged students seeking to enroll in four-year colleges/universities upon high…

78 FR 36223 - Extension and Redesignation of Syria for Temporary Protected Status

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-17

... toll-free number). Note: The phone number provided here is solely for questions regarding this TPS... Authorization Document FSA--Free Syrian Army Government--U.S. Government IDP--Internally Displaced Persons IJ.... In addition to the Free Syrian Army (FSA) and Syrian National Army, reports published in 2012...

AF-Shell 1.0 User Guide

NASA Technical Reports Server (NTRS)

McElroy, Mark W.

2017-01-01

This document serves as a user guide for the AF-Shell 1.0 software, an efficient tool for progressive damage simulation in composite laminates. This guide contains minimal technical material and is meant solely as a guide for a new user to apply AF-Shell 1.0 to laminate damage simulation problems.

Identifying Indicators of Behavior Change: Insights from Wildfire Education Programs

ERIC Educational Resources Information Center

Monroe, Martha C.; Agrawal, Shruti; Jakes, Pamela J.; Kruger, Linda E.; Nelson, Kristen C.; Sturtevant, Victoria

2013-01-01

Environmental educators are challenged to document behavior changes, because change rarely depends solely on outcomes of education programs, but on many factors. An analysis of 15 communities in the United States that have increased their preparedness for wildfire allowed us to explore how education programs encouraged individual and community…

40 CFR 749.68 - Hexavalent chromium-based water treatment chemicals in cooling systems.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Person means any natural person, firm, company, corporation, joint venture, partnership, sole... in one location at the headquarters of the distributor documentation showing: (i) The name, address... shall report to the Regional Administrator of the EPA Region in which the distibutor headquarters is...

34 CFR 675.27 - Nature and source of institutional share.

Code of Federal Regulations, 2010 CFR

2010-07-01

... employment agreement to do so. (Approved by the Office of Management and Budget under control number 1840..., board, and books. (2) The institution shall document all amounts claimed as non-cash contributions. (3) Non-cash compensation may not include forgiveness of a charge assessed solely because of a student's...

Periodic Review Report: April 1984-June 1988.

ERIC Educational Resources Information Center

Williamsport Area Community Coll., PA.

This report documents actions, accomplishments, and modifications at the Williamsport Area Community College (WACC) between April 1984 and June 1988. First, an executive summary highlights the following: (1) in 1985, WACC underwent a significant change in its governance when the City of Williamsport became the college's sole sponsor; (2) as a…

12 CFR 204.124 - Repurchase agreement involving shares of a money market mutual fund whose portfolio consists...

Code of Federal Regulations, 2010 CFR

2010-01-01

... money market mutual fund whose portfolio consists wholly of United States Treasury and Federal agency... § 204.124 Repurchase agreement involving shares of a money market mutual fund whose portfolio consists... (i.e., money market mutual funds) provided the portfolios of such companies consist solely of...

12 CFR 204.124 - Repurchase agreement involving shares of a money market mutual fund whose portfolio consists...

Code of Federal Regulations, 2011 CFR

2011-01-01

... money market mutual fund whose portfolio consists wholly of United States Treasury and Federal agency... § 204.124 Repurchase agreement involving shares of a money market mutual fund whose portfolio consists... (i.e., money market mutual funds) provided the portfolios of such companies consist solely of...

76 FR 65758 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-24

... placements, provide relevant disclosures to each investor prior to sale describing the anticipated use of... Placements of Securities) to ensure that investors in private placements are provided detailed information... information filed pursuant to the Rule, and would use such documents and information solely for the purpose of...

Teaching about Ethnic Conflict: Global Issues. Ethnic Heritage Series, Volume 2.

ERIC Educational Resources Information Center

Lamy, Steven L.

The document presents background information and activities for use by secondary school social studies teachers as they incorporate material on ethnic conflict into the curriculum. Ethnic conflicts are interpreted as hostilities which are either solely based upon or accentuated by ethnic differences. Examples are violence in Northern Ireland,…

Identifying indicators of behavior change: insights from wildfire education programs

Treesearch

Martha C. Monroe; Shruti Agrawal; Pamela J. Jakes; Linda E. Kruger; Kristen C. Nelson; Victoria Sturtevant

2013-01-01

Environmental educators are challenged to document behavior changes, because change rarely depends solely on outcomes of education programs, but on many factors. An analysis of 15 communities in the United States that have increased their preparedness for wildfire allowed us to explore how education programs encouraged individual and community change. Agency-sponsored...

45 CFR 1206.1-7 - Termination hearing procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... allowed solely for the aid and information of the presiding officer. (e) Filing. All papers and documents which are required to be filed shall be filed with the presiding officer. Prior to filing, copies shall... proceeding, and may be limited to the filing of written material. (2) Any person or organization that wishes...

Protect Yourself! How To Minimize Your Risk of an IRS Audit.

ERIC Educational Resources Information Center

Lukaszewski, Thomas; Moser, Barbara

1998-01-01

Shows how to minimize risk of an IRS audit and how to avoid traps caused by improper documentation and reporting requirements. Outlines the most likely audit areas for business tax returns. These include cash business; for sole proprietors, Schedule C; S and C corporation salary issues; shareholder loans; contractors versus employees; fringe…

10 CFR 1003.5 - Computation of time.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., the day of the act, event, or default from which the designated period of time begins to run is not to..., or federal legal holiday, in which event the period runs until the end of the next day that is not a..., notice or other document is served solely by mail, 3 days shall be added to the prescribed period. ...

10 CFR 1003.5 - Computation of time.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., the day of the act, event, or default from which the designated period of time begins to run is not to..., or federal legal holiday, in which event the period runs until the end of the next day that is not a..., notice or other document is served solely by mail, 3 days shall be added to the prescribed period. ...

10 CFR 1003.5 - Computation of time.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., the day of the act, event, or default from which the designated period of time begins to run is not to..., or federal legal holiday, in which event the period runs until the end of the next day that is not a..., notice or other document is served solely by mail, 3 days shall be added to the prescribed period. ...

10 CFR 1003.5 - Computation of time.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., the day of the act, event, or default from which the designated period of time begins to run is not to..., or federal legal holiday, in which event the period runs until the end of the next day that is not a..., notice or other document is served solely by mail, 3 days shall be added to the prescribed period. ...

10 CFR 1003.5 - Computation of time.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., the day of the act, event, or default from which the designated period of time begins to run is not to..., or federal legal holiday, in which event the period runs until the end of the next day that is not a..., notice or other document is served solely by mail, 3 days shall be added to the prescribed period. ...

The Formation of the World Council of Indigenous Peoples. IWGIA Document 29.

ERIC Educational Resources Information Center

Sanders, Douglas E.

Once European sovereignty had been established, colonial powers regarded the affairs of the colonized area as "internal", meaning that indigenous rights were to be governed solely by the colonial power. It was George Manuel, a British Columbia Indian and President of the National Indian Brotherhood, 1970-76, who conceived the idea of an…

NCEP BUFRLIB Software User Guide

Science.gov Websites

Integration Branch > Decoders > BUFRLIB BUFRLIB Software User Guide This document set describes how to use the NCEP BUFRLIB software to encode or decode BUFR messages. It is not intended to be a primer on background knowledge of the basic concepts of BUFR and will focus solely on how to use the BUFRLIB software

PROCEEDINGS: 1989 JOINT SYMPOSIUM ON STATIONARY COMBUSTION NOX CONTROL, SAN FRANCISCO, CA, MARCH 6-9, 1989 VOLUME 1

EPA Science Inventory

The proceedings document presentations at the 1989 Joint Symposium on Stationary Combustion NOx Control, held March 6-9, 1989, in San Francisco, CA. The symposium, sponsored by the U. S. EPA and EPRl, was the fifth in a series devoted solely to the discussion of control of NOx em...

PROCEEDINGS: 1989 JOINT SYMPOSIUM ON STATIONARY COMBUSTION NOX CONTROL, SAN FRANCISCO, CA, MARCH 6-9, 1989 VOLUME 2

EPA Science Inventory

The proceedings document presentations at the 1989 Joint Symposium on Stationary Combustion NOx Control, held March 6-9. 1989. in San Francisco, CA. The symposium, sponsored by the U.S. EPA and EPRI, was the fifth in a series devoted solely to the discussion of control of NOx emi...

13 CFR 124.503 - How does SBA accept a procurement for award through the 8(a) BD program?

Code of Federal Regulations, 2011 CFR

2011-01-01

... market research, the contracting officer shall first consider a set-aside or sole source award (if the... market research conducted. In addition, the contracting officer must document the contract file showing... factors such as the results of market research, programmatic needs specific to the procuring agency...

What Benefits Could Extension Papers and Admissions Tests Have for University Mathematics Applicants?

ERIC Educational Resources Information Center

Darlington, Ellie

2015-01-01

It is well documented in both the British press and mathematics education literature that many consider A-levels (qualifications for secondary school leavers in England, Wales and Northern Ireland) to be insufficient preparation for undergraduate mathematics study in the UK. A-level Mathematics and Further Mathematics are not solely intended for…

Utilizing the Virtual Communication Sport-Delivery Model to Promote Extracurricular Athletics for Students with Disabilities

ERIC Educational Resources Information Center

Busse, Sean; Davis, Ronald

2016-01-01

In 2010, the United States Government Accountability Office (GAO) reevaluated the status of Public Law 93-112, Sec 504, which protects against discrimination solely based on someone's disability. Recommendations and findings were reported to school districts around the country in a document called the Dear Colleague Letter of 2013. The GAO…

Hypnosis as sole anesthesia for major surgeries: historical & contemporary perspectives.

PubMed

Hammond, D Corydon

2008-10-01

Hypnosis is a well validated treatment for acute and chronic pain (Montgomery, DuHamel, & Redd, 2000). It has been found capable of reducing inflammation, altering blood flow, and producing beneficial effects when hypnotic suggestions are provided during and prior to surgery (Frederick, 2001) and other painful medical procedures. This paper quotes extensively from historical examples of the use of hypnosis (mesmerism) as the sole anesthesia for major surgeries in the 1800's. These historic examples by themselves provide powerful documentation of the ability of the mind to influence the body, but they are then followed by a review of contemporary literature and controlled research on the use in hypnosis in relation to surgery and prior to medical procedures.

Comparison of statistical models for writer verification

NASA Astrophysics Data System (ADS)

Srihari, Sargur; Ball, Gregory R.

2009-01-01

A novel statistical model for determining whether a pair of documents, a known and a questioned, were written by the same individual is proposed. The goal of this formulation is to learn the specific uniqueness of style in a particular author's writing, given the known document. Since there are often insufficient samples to extrapolate a generalized model of an writer's handwriting based solely on the document, we instead generalize over the differences between the author and a large population of known different writers. This is in contrast to an earlier model proposed whereby probability distributions were a priori without learning. We show the performance of the model along with a comparison in performance to the non-learning, older model, which shows significant improvement.

21 CFR 73.2150 - Dihydroxyacetone.

Code of Federal Regulations, 2014 CFR

2014-04-01

... ADDITIVES EXEMPT FROM CERTIFICATION Cosmetics § 73.2150 Dihydroxyacetone. (a) Identity and specifications... amounts consistent with good manufacturing practice in externally applied cosmetics intended solely or in...

21 CFR 73.2150 - Dihydroxyacetone.

Code of Federal Regulations, 2013 CFR

2013-04-01

... ADDITIVES EXEMPT FROM CERTIFICATION Cosmetics § 73.2150 Dihydroxyacetone. (a) Identity and specifications... amounts consistent with good manufacturing practice in externally applied cosmetics intended solely or in...

21 CFR 73.2150 - Dihydroxyacetone.

Code of Federal Regulations, 2012 CFR

2012-04-01

... ADDITIVES EXEMPT FROM CERTIFICATION Cosmetics § 73.2150 Dihydroxyacetone. (a) Identity and specifications... amounts consistent with good manufacturing practice in externally applied cosmetics intended solely or in...

Synchronous formation of the metamorphic sole and igneous crust of the Semail ophiolite: New constraints on the tectonic evolution during ophiolite formation from high-precision U-Pb zircon geochronology

NASA Astrophysics Data System (ADS)

Rioux, Matthew; Garber, Joshua; Bauer, Ann; Bowring, Samuel; Searle, Michael; Kelemen, Peter; Hacker, Bradley

2016-10-01

The Semail (Oman-United Arab Emirates) and other Tethyan-type ophiolites are underlain by a sole consisting of greenschist- to granulite-facies metamorphic rocks. As preserved remnants of the underthrust plate, sole exposures can be used to better understand the formation and obduction of ophiolites. Early models envisioned that the metamorphic sole of the Semail ophiolite formed as a result of thrusting of the hot ophiolite lithosphere over adjacent oceanic crust during initial emplacement; however, calculated pressures from granulite-facies mineral assemblages in the sole suggest the metamorphic rocks formed at >35 km depth, and are too high to be explained by the currently preserved thickness of ophiolite crust and mantle (up to 15-20 km). We have used high-precision U-Pb zircon dating to study the formation and evolution of the metamorphic sole at two well-studied localities. Our previous research and new results show that the ophiolite crust formed from 96.12-95.50 Ma. Our new dates from the Sumeini and Wadi Tayin sole localities indicate peak metamorphism at 96.16 and 94.82 Ma (±0.022 to 0.035 Ma), respectively. The dates from the Sumeini sole locality show for the first time that the metamorphic rocks formed either prior to or during formation of the ophiolite crust, and were later juxtaposed with the base of the ophiolite. These data, combined with existing geochemical constraints, are best explained by formation of the ophiolite in a supra-subduction zone setting, with metamorphism of the sole rocks occurring in a subducted slab. The 1.3 Ma difference between the Wadi Tayin and Sumeini dates indicates that, in contrast to current models, the highest-grade rocks at different sole localities underwent metamorphism, and may have returned up the subduction channel, at different times.

The oligolectic bee Osmia brevis sonicates Penstemon flowers for pollen: A newly documented behavior for the Megachilidae

Treesearch

James H. Cane

2014-01-01

Flowers with poricidally dehiscent anthers are typically nectarless but are avidly visited and often solely pollinated by bees that sonicate the flowers to harvest pollen. Sonication results from shivering the thoracic flight muscles. Honey bees (Apis) and the 4,000+ species of Megachilidae are enigmatic in their seeming inability to sonicate flowers. The oligolectic...

Differences in Persistence Patterns between Life and Physical Science Majors: The Role of Grades, Peers, and Preparation

ERIC Educational Resources Information Center

Ost, Ben

2010-01-01

Using longitudinal administrative data from a large elite research university, this paper separately analyzes the determinants of persistence for life and physical science majors. My results confirm much of the previous research on major persistence in the sciences, but I document that many findings are solely driven by persistence patterns in the…

Evaluation of the Carcinogenicity of Ethylene Oxide (2006 ...

EPA Pesticide Factsheets

EPA conducted a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of ethylene oxide (cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database. EPA is announcing a 30-day public comment period for this document. The release of this draft document is solely for the purpose of seeking public comment and for review by the EPA Science Advisory Board (SAB) via a meeting to be held later in 2006. The time and place of the SAB meeting will be announced in a separate Federal Register notice. This document has not been formally disseminated by EPA and does not represent, and should not be construed to represent, any Agency policy or determination. EPA will consider any public comments submitted in accordance with the requirements specified in the Notice of Public Comment Period when revising this draft document.

Apogeotropic central positional nystagmus as a sole sign of nodular infarction.

PubMed

Kim, Hyun-Ah; Yi, Hyon-Ah; Lee, Hyung

2012-10-01

Positional vertigo and nystagmus without associated neurological symptoms and signs are characteristic features of benign paroxysmal positional vertigo (BPPV). Although positional nystagmus may occur with caudal cerebellar infarction including the nodulus, positional nystagmus is usually associated with other neurological signs such as spontaneous or gaze-evoked nystagmus, perverted head-shaking nystagmus, cerebellar dysmetria, or severe gait ataxia with falling. We present a patient with nodular infarction who had positional vertigo with nystagmus as a sole manifestation. Video-oculography showed apogeotropic positional horizontal nystagmus during head turning while supine, which was consistent with apogeotropic BPPV involving the horizontal canal. MRI disclosed acute infarct in the nodulus. Nodulus infarction should be considered in a patient with positional nystagmus, especially when the presenting symptoms and signs are consistent with BPPV involving the horizontal canal.

Cognitive and Non-cognitive Predictors of Career Intentions within Cyber Jobs

DTIC Science & Technology

2016-04-01

in Anaheim, California, April 14-16, 2016. 15. SUBJECT TERMS Cyber, career intentions, retention , cognitive ability, job fit, normative commitment...Predictors of Cyber Job Career Intentions 1 The views, opinions, and findings contained in this article are solely those of the authors and should...other documentation. Cognitive and Non-cognitive Predictors of Career Intentions within Cyber Jobs Kristophor Canali U. S. Army

Promethazine as a Novel Prophylaxis and Treatment for Nerve Agent Poisoning

DTIC Science & Technology

2008-12-01

mitochondrial dysfunction. Mitochondrial damage after seizure activity has been previously documented (Cock et al., 2002), and mitochondrial...McDonough et al., 1998), the lack of brain pathology in surviving animals is solely due to the secondary anticholinergic activity of promethazine...rats, Experientia, 41(11), 1457-1458. Department of Health, Expert group on the management of chemical casualties by terrorist activity , 2003: Use

Sacroiliitis as a sole manifestation of Brucella melitensis infection in a child

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miron, D.; Garty, I.; Tal, I.

A case of a 12-year-old boy with sacroiliitis documented by positive Tc-99m MDP and Ga-67 scans is described. Isolation of brucella melitensis from the blood and bone marrow established the diagnosis. He responded promptly to docycycline therapy. Throughout the course of his disease this boy had neither fever nor other signs of brucellosis, and x-ray was normal.

Morphological Priming Survives a Language Switch

ERIC Educational Resources Information Center

Verdonschot, Rinus G.; Middelburg, Renee; Lensink, Saskia E.; Schiller, Niels O.

2012-01-01

In a long-lag morphological priming experiment, Dutch (L1)-English (L2) bilinguals were asked to name pictures and read aloud words. A design using non-switch blocks, consisting solely of Dutch stimuli, and switch-blocks, consisting of Dutch primes and targets with intervening English trials, was administered. Target picture naming was facilitated…

Behavioral Indicators of Drug Carrying in Open Spaces

DTIC Science & Technology

2015-04-30

approached by that patrol. The findings of Phase I was documented in three reports. These reports include: 1) Behavioral Indicators of Illegal and Legal ...not focus solely on persons carrying firearms or drugs because there are jurisdiction-specific legal and use-of-force elements which dictate the...to develop training for law enforcement and security personnel to utilize behavioral indicators in a safe, legal , and effective manner. Training

Hawaii State Plan for Occupational Safety and Health. Final rule.

PubMed

2012-09-21

This document announces the Occupational Safety and Health Administration's (OSHA) decision to modify the Hawaii State Plan's ``final approval'' determination under Section 18(e) of the Occupational Safety and Health Act (the Act) and to transition to ``initial approval'' status. OSHA is reinstating concurrent federal enforcement authority over occupational safety and health issues in the private sector, which have been solely covered by the Hawaii State Plan since 1984.

An Efficacy Study of Interleaved Mathematics Practice. Revised

ERIC Educational Resources Information Center

Rohrer, Doug; Dedrick, Robert F.; Burgess, Kaleena

2013-01-01

In a typical mathematics course, the material is divided into many lessons, and each lesson is followed by an assignment consisting of practice problems. Most commonly, each assignment consists solely of problems on the preceding lesson. For example, a lesson on ratios might be followed by an assignment with 12 problems on ratios. In other words,…

Quantitative assessment of the equine hoof using digital radiography and magnetic resonance imaging.

PubMed

Grundmann, I N M; Drost, W T; Zekas, L J; Belknap, J K; Garabed, R B; Weisbrode, S E; Parks, A H; Knopp, M V; Maierl, J

2015-09-01

Evaluation of laminitis cases relies on radiographic measurements of the equine foot. Reference values have not been established for all layers of the foot. To establish normal hoof wall and sole measurements using digital radiography (DR) and magnetic resonance imaging (MRI) and to document tissue components present in the dorsal hoof wall and solar layers seen on DR. Prospective observational case-control study. Digital radiography and MRI were performed on 50 cadaver front feet from 25 horses subjected to euthanasia for nonlameness-related reasons. Four observers measured hoof wall (dorsal, lateral and medial) and sole thickness (sagittal, lateral and medial) using DR and magnetic resonance images. One observer repeated the measurements 3 times. Inter- and intraobserver correlation was assessed. Digital radiography and MRI measurements for the normal hoof wall and sole were established. Inter- and intraobserver pairwise Pearson's correlation for DR (r>0.98) and MRI measurements (r>0.99) was excellent. Based on MRI, the less radiopaque layer on DR is comprised of the stratum lamellatum and stratum reticulare. Normal DR and MRI measurements for the hoof wall and sole were established. On DR images, the less radiopaque layer of the foot observed corresponds to the critical tissues injured in laminitis, the strata lamellatum and reticulare. These reference measurements may be used by the clinician to detect soft-tissue changes in the laminitic equine foot and provide a foundation for future research determining changes in these measurements in horses with laminitis. © 2014 EVJ Ltd.

Documenting Climate Models and Simulations: the ES-DOC Ecosystem in Support of CMIP

NASA Astrophysics Data System (ADS)

Pascoe, C. L.; Guilyardi, E.

2017-12-01

The results of climate models are of increasing and widespread importance. No longer is climate model output of sole interest to climate scientists and researchers in the climate change impacts and adaptation fields. Now non-specialists such as government officials, policy-makers, and the general public, all have an increasing need to access climate model output and understand its implications. For this host of users, accurate and complete metadata (i.e., information about how and why the data were produced) is required to document the climate modeling results. Here we describe the ES-DOC community-govern project to collect and make available documentation of climate models and their simulations for the internationally coordinated modeling activity CMIP6 (Coupled Model Intercomparison Project, Phase 6). An overview of the underlying standards, key properties and features, the evolution from CMIP5, the underlying tools and workflows as well as what modelling groups should expect and how they should engage with the documentation of their contribution to CMIP6 is also presented.

Leukoproliferative response of splenocytes from English sole (Pleuronectes vetulus) exposed to chemical contaminants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arkoosh, M.R.; Clemons, E.; Huffman, P.

The leukoproliferative (LP) response of splenic leukocytes from the marine benthic fish English sole (Pleuronectes vetulus) stimulated with the mitogens lipopolysaccharide (LPS), convanavalin A (Con A), and pokeweed mitogen (PWM) was examined as a biomarker of immunotoxic effects. English sole were exposed to contaminants, either by injection of an organic-solvent extract of a sediment containing polycyclic aromatic compounds (PACs) or placed for up to 5 weeks on a reference sediment containing 0.15 to 1.5% (v/v) of the PAC-contaminated sediment. English sole either injected with the contaminated extract or held on PAC-contaminated sediment had an augmented response to Con A. Themore » LP response to LPS showed no relationship to PAC exposure in laboratory-exposed fish, while PWM showed no consistent relationship to exposure to PACs. In a field study, English sole captured from an urban area in Puget Sound, Washington, USA, contaminated with PACs and other chemical contaminants had a significantly augmented LP response to Con A and PWM in comparison to the LP response in fish from a nonurban reference site. Fish from another nonurban site also had an augmented LP response to Con A, indicating that the elevation of the Con A LP response can also result from factors other than chemical contaminant exposure. In addition, English sole from this site also had an augmented LP response to LPS, whereas fish from urban sites did not exhibit an augmented LP response to LPS. Overall, the results demonstrated that although the LP response in splenic leukocytes of English sole to Con A was linked to contaminant exposure, the LP response to Con A did not exhibit high specificity as an indicator of chemical contaminant exposure. However, the concerted use of Con A, LPS, and PWM allowed for identification of apparent chemical contaminant-induced alterations of the LP response in English sole from an urban area of Puget Sound.« less

26 CFR 1.1082-6 - Basis of property acquired under section 1081(d) in transactions between corporations of the same...

Code of Federal Regulations, 2010 CFR

2010-04-01

... were the sole consideration for the property transferred to the corporation issuing such stock or... acquired consists of stock or securities, money, and other property, or any of them, but it is contemplated... to the general rule is provided for in case the property acquired consists of stock or securities...

An Exploratory Study: Assessment of Modeled Dioxin ...

EPA Pesticide Factsheets

EPA has released an external review draft entitled, An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios(External Review Draft). The public comment period and the external peer-review workshop are separate processes that provide opportunities for all interested parties to comment on the document. In addition to consideration by EPA, all public comments submitted in accordance with this notice will also be forwarded to EPA’s contractor for the external peer-review panel prior to the workshop. EPA has realeased this draft document solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination. The purpose of this report is to describe an exploratory investigation of potential dioxin exposures to artists/hobbyists who use ball clay to make pottery and related products.

Our Children Are Hurting: Fact Sheet on the Disproportionate Involvement of Indian Young People in the Juvenile Justice and Child Welfare Systems in Ontario, 1981-1982.

ERIC Educational Resources Information Center

Jolly, Stan

This fact sheet documents the disturbing overrepresentation of status Indian youth in the juvenile justice and child welfare systems of Ontario (Canada). However, the information represents only the tip of the iceberg. Data relate solely to children and youth whose parents resided on an Indian reserve; who were dealt with by the family court (not…

27 CFR 479.32a - Reduced rate of tax for small importers and manufacturers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... MACHINE GUNS, DESTRUCTIVE DEVICES, AND CERTAIN OTHER FIREARMS Special (Occupational) Taxes § 479.32a... 50% control over a group consisting of corporations and one, or more, partnerships and/or sole...

27 CFR 479.32a - Reduced rate of tax for small importers and manufacturers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... MACHINE GUNS, DESTRUCTIVE DEVICES, AND CERTAIN OTHER FIREARMS Special (Occupational) Taxes § 479.32a... 50% control over a group consisting of corporations and one, or more, partnerships and/or sole...

27 CFR 479.32a - Reduced rate of tax for small importers and manufacturers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... MACHINE GUNS, DESTRUCTIVE DEVICES, AND CERTAIN OTHER FIREARMS Special (Occupational) Taxes § 479.32a... 50% control over a group consisting of corporations and one, or more, partnerships and/or sole...

27 CFR 479.32a - Reduced rate of tax for small importers and manufacturers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... MACHINE GUNS, DESTRUCTIVE DEVICES, AND CERTAIN OTHER FIREARMS Special (Occupational) Taxes § 479.32a... 50% control over a group consisting of corporations and one, or more, partnerships and/or sole...

Updated analysis of flatfish recruitment response to climate variability and ocean conditions in the Eastern Bering Sea

NASA Astrophysics Data System (ADS)

Wilderbuer, Thomas; Stockhausen, William; Bond, Nicholas

2013-10-01

This study provides a retrospective analysis of the relationship between physical oceanography, biology and recruitment of three Eastern Bering Sea flatfish stocks: flathead sole (Hippoglossoides elassodon), northern rock sole (Lepidopsetta polyxystra), and arrowtooth flounder (Atheresthes stomias) during the period 1978-2005. Stock assessment model estimates of recruitment and spawning stock size indicate that temporal patterns in productivity are consistent with decadal scale (or shorter) patterns in climate variability, which may influence marine survival during the early life history phases. Density-dependence (through spawning stock size) was statistically significant in a Ricker stock-recruit model of flatfish recruitment that included environmental terms. Wind-driven advection of northern rock sole and flathead sole larvae to favorable nursery grounds was found to coincide with years of above-average recruitment. Ocean forcing of Bristol Bay surface waters during springtime was mostly on-shelf (eastward) during the 1980s and again in the early 2000s, but was off-shelf (westerly) during the 1990s, corresponding with periods of good and poor recruitment, respectively. Finally, the Arctic Oscillation was found to be an important indicator of arrowtooth flounder productivity. Model results were applied to IPCC (Intergovernmental Panel on Climate Change) future springtime wind scenarios to predict the future impact of climate on northern rock sole productivity and indicated that a moderate future increase in recruitment might be expected because the climate trends favor on-shelf transport but that density-dependence will dampen this effect such that northern rock sole abundance will not be substantially affected by climate change.

Biologically active LIL proteins built with minimal chemical diversity

PubMed Central

Heim, Erin N.; Marston, Jez L.; Federman, Ross S.; Edwards, Anne P. B.; Karabadzhak, Alexander G.; Petti, Lisa M.; Engelman, Donald M.; DiMaio, Daniel

2015-01-01

We have constructed 26-amino acid transmembrane proteins that specifically transform cells but consist of only two different amino acids. Most proteins are long polymers of amino acids with 20 or more chemically distinct side-chains. The artificial transmembrane proteins reported here are the simplest known proteins with specific biological activity, consisting solely of an initiating methionine followed by specific sequences of leucines and isoleucines, two hydrophobic amino acids that differ only by the position of a methyl group. We designate these proteins containing leucine (L) and isoleucine (I) as LIL proteins. These proteins functionally interact with the transmembrane domain of the platelet-derived growth factor β-receptor and specifically activate the receptor to transform cells. Complete mutagenesis of these proteins identified individual amino acids required for activity, and a protein consisting solely of leucines, except for a single isoleucine at a particular position, transformed cells. These surprisingly simple proteins define the minimal chemical diversity sufficient to construct proteins with specific biological activity and change our view of what can constitute an active protein in a cellular context. PMID:26261320

Software development without languages

NASA Technical Reports Server (NTRS)

Osborne, Haywood S.

1988-01-01

Automatic programming generally involves the construction of a formal specification; i.e., one which allows unambiguous interpretation by tools for the subsequent production of the corresponding software. Previous practical efforts in this direction have focused on the serious problems of: (1) designing the optimum specification language; and (2) mapping (translating or compiling) from this specification language to the program itself. The approach proposed bypasses the above problems. It postulates that the specification proper should be an intermediate form, with the sole function of containing information sufficient to facilitate construction of programs and also of matching documentation. Thus, the means of forming the intermediary becomes a human factors task rather than a linguistic one; human users will read documents generated from the specification, rather than the specification itself.

Thresholds of skin sensitivity are partially influenced by mechanical properties of the skin on the foot sole

PubMed Central

Strzalkowski, Nicholas D J; Triano, John J; Lam, Chris K; Templeton, Cale A; Bent, Leah R

2015-01-01

Across the foot sole, there are vibration and monofilament sensory differences despite an alleged even distribution of cutaneous afferents. Mechanical property differences across foot sole sites have been proposed to account for these differences. Vibration (VPT; 3 Hz, 40 Hz, 250 Hz), and monofilament (MF) perception threshold measurements were compared with skin hardness, epidermal thickness, and stretch response across five foot sole locations in young healthy adults (n = 22). Perceptual thresholds were expected to correlate with all mechanical property measurements to help address sensitivity differences between sites. Following this hypothesis, the MedArch was consistently found to be the thinnest and softest site and demonstrated the greatest sensitivity. Conversely, the Heel was found to be the thickest and hardest site, and was relatively insensitive across perceptual tests. Site differences were not observed for epidermal stretch response measures. Despite an apparent trend of elevated sensory threshold at harder and thicker sites, significant correlations between sensitivity measures and skin mechanical properties were not observed. Skin hardness and epidermal thickness appeared to have a negligible influence on VPT and minor influence on MF within this young healthy population. When normalized (% greater or smaller than subject mean) to the subject mean for each variable, significant positive correlations were observed between MF and skin hardness (R2 = 0.422, P < 0.0001) and epidermal thickness (R2 = 0.433, P < 0.0001) providing evidence that skin mechanics can influence MF threshold. In young healthy adults, differences in sensitivity are present across the foot sole, but cannot solely be accounted for by differences in the mechanical properties of the skin. PMID:26059035

Allineamento della Basilica di san Pietro col Sole

NASA Astrophysics Data System (ADS)

Sigismondi, Costantino; Regoli, Irene

2017-06-01

The obelisk of St Peter in Vatican is not centered with the Basilica's axis; its alignment is measured with the Sun azimuth as 88°59'±1', consistent with the rising azimuth of the ecclesiastic equinox, 21 march 315.

John F. Kennedy Space Center, Safety, Reliability, Maintainability and Quality Assurance, Survey and Audit Program

NASA Technical Reports Server (NTRS)

1994-01-01

This document is the product of the KSC Survey and Audit Working Group composed of civil service and contractor Safety, Reliability, and Quality Assurance (SR&QA) personnel. The program described herein provides standardized terminology, uniformity of survey and audit operations, and emphasizes process assessments rather than a program based solely on compliance. The program establishes minimum training requirements, adopts an auditor certification methodology, and includes survey and audit metrics for the audited organizations as well as the auditing organization.

Common Factors and Outcome in Late Upper Extremity Amputations After Military Injury

DTIC Science & Technology

2014-04-01

documentation, if this pain was solely phan- tom limb pain or a different type of neuropathic pain. Only 1 (14%) had a chronic infection . Table 1... Infection 1 14% Malunion 1 14% Nonunion 1 14% Krueger et al J Orthop Trauma Volume 28, Number 4, April 2014 228 | www.jorthotrauma.com 2013... infections to be the most common reasons why those with lower extrem- ities underwent late amputations. Tintle et al5 also found infec- tion and wound

British American Tobacco's failure in Turkey.

PubMed

Lawrence, S

2009-02-01

Transnational tobacco companies (TTCs) considered Turkey an important, potential investment market because of its high consumption rates and domestic commitment to tobacco. This paper outlines how British American Tobacco (BAT) attempted to establish a joint venture with the government monopoly TEKEL, while waiting for privatisation and a private tender. Analysis of tobacco industry documents from the Guildford Depository and online tobacco document sources. BAT failed to establish a market share in Turkey until 2000 despite repeated attempts to form a joint venture with Turkey's tobacco monopoly, TEKEL, once the market liberalised in the mid 1980s. BAT's failure in the Turkish market was due to a misguided investment strategy focused solely on acquiring TEKEL and is contrasted with Philip Morris success in Turkey despite both TTCs working within Turkey's unstable and corrupt investing climate.

75 FR 15415 - Certain Crepe Paper Products From the People's Republic of China: Final Results of Expedited...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-29

... order may consist solely of crepe paper of one color and/or style, or may contain multiple colors and/or... Manufacturers/exporters/producers (percent) Fuzhou Light Industry Import and Export Co., Ltd 266.83 Fuzhou...

Spectral Classes for FAA's Integrated Noise Model Version 6.0.

DOT National Transportation Integrated Search

1999-12-07

The starting point in any empirical model such as the Federal Aviation Administrations (FAA) : Integrated Noise Model (INM) is a reference data base. In Version 5.2 and in previous versions : the reference data base consisted solely of a set of no...

Documenting Climate Models and Their Simulations

DOE PAGES

Guilyardi, Eric; Balaji, V.; Lawrence, Bryan; ...

2013-05-01

The results of climate models are of increasing and widespread importance. No longer is climate model output of sole interest to climate scientists and researchers in the climate change impacts and adaptation fields. Now nonspecialists such as government officials, policy makers, and the general public all have an increasing need to access climate model output and understand its implications. For this host of users, accurate and complete metadata (i.e., information about how and why the data were produced) is required to document the climate modeling results. We describe a pilot community initiative to collect and make available documentation of climatemore » models and their simulations. In an initial application, a metadata repository is being established to provide information of this kind for a major internationally coordinated modeling activity known as CMIP5 (Coupled Model Intercomparison Project, Phase 5). We expected that for a wide range of stakeholders, this and similar community-managed metadata repositories will spur development of analysis tools that facilitate discovery and exploitation of Earth system simulations.« less

Do third-party plans really pay for CVS care?

PubMed

Soden, Richard

2002-04-01

Until specific CPT and ICD-9 codes are created and approved for CVS, and until there is uniform agreement that CVS is a true medical anomaly (or not), each practitioner will have to decide on how to bill for the signs and symptoms of Computer Vision Syndrome. If the practitioner chooses to view CVS as a medical problem, then the same guidelines and rules for all other patients should be followed with appropriate documentation using CPT and ICD-9 coding. If the practitioner chooses to consider CVS solely as an optical problem, this is a "noncovered" service and the patient or any applicable optical plan will be responsible for payment. One final note: each practitioner who tests for CVS will also have to determine if there is a separate fee for CVS testing. If the practitioner considers CVS to be a medical problem, it may be applicable to include testing for Computer Vision Syndrome as an incidental test to the medical office visit. If the practitioner chooses to consider CVS to be purely an optical problem, it may be appropriate to add an appropriate charge to the noncovered examination. Whatever the decision is, there must be consistency from patient to patient.

Vehicle Integrated Prognostic Reasoner (VIPR) Metric Report

NASA Technical Reports Server (NTRS)

Cornhill, Dennis; Bharadwaj, Raj; Mylaraswamy, Dinkar

2013-01-01

This document outlines a set of metrics for evaluating the diagnostic and prognostic schemes developed for the Vehicle Integrated Prognostic Reasoner (VIPR), a system-level reasoner that encompasses the multiple levels of large, complex systems such as those for aircraft and spacecraft. VIPR health managers are organized hierarchically and operate together to derive diagnostic and prognostic inferences from symptoms and conditions reported by a set of diagnostic and prognostic monitors. For layered reasoners such as VIPR, the overall performance cannot be evaluated by metrics solely directed toward timely detection and accuracy of estimation of the faults in individual components. Among other factors, overall vehicle reasoner performance is governed by the effectiveness of the communication schemes between monitors and reasoners in the architecture, and the ability to propagate and fuse relevant information to make accurate, consistent, and timely predictions at different levels of the reasoner hierarchy. We outline an extended set of diagnostic and prognostics metrics that can be broadly categorized as evaluation measures for diagnostic coverage, prognostic coverage, accuracy of inferences, latency in making inferences, computational cost, and sensitivity to different fault and degradation conditions. We report metrics from Monte Carlo experiments using two variations of an aircraft reference model that supported both flat and hierarchical reasoning.

Saline as the Sole Contrast Agent for Successful MRI-guided Epidural Injections

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deli, Martin, E-mail: martin.deli@web.de; Fritz, Jan, E-mail: jfritz9@jhmi.edu; Mateiescu, Serban, E-mail: mateiescu@microtherapy.de

Purpose. To assess the performance of sterile saline solution as the sole contrast agent for percutaneous magnetic resonance imaging (MRI)-guided epidural injections at 1.5 T. Methods. A retrospective analysis of two different techniques of MRI-guided epidural injections was performed with either gadolinium-enhanced saline solution or sterile saline solution for documentation of the epidural location of the needle tip. T1-weighted spoiled gradient echo (FLASH) images or T2-weighted single-shot turbo spin echo (HASTE) images visualized the test injectants. Methods were compared by technical success rate, image quality, table time, and rate of complications. Results. 105 MRI-guided epidural injections (12 of 105 withmore » gadolinium-enhanced saline solution and 93 of 105 with sterile saline solution) were performed successfully and without complications. Visualization of sterile saline solution and gadolinium-enhanced saline solution was sufficient, good, or excellent in all 105 interventions. For either test injectant, quantitative image analysis demonstrated comparable high contrast-to-noise ratios of test injectants to adjacent body substances with reliable statistical significance levels (p < 0.001). The mean table time was 22 {+-} 9 min in the gadolinium-enhanced saline solution group and 22 {+-} 8 min in the saline solution group (p = 0.75). Conclusion. Sterile saline is suitable as the sole contrast agent for successful and safe percutaneous MRI-guided epidural drug delivery at 1.5 T.« less

76 FR 27636 - Permits; Foreign Fishing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-12

... all electronic public comments via the Federal eRulemaking Portal at http://www.regulations.gov . Mail... by e- mail at [email protected] . SUPPLEMENTARY INFORMATION: Background Section 204(d) of the... consisting solely of transporting fish or fish products at sea from a point within the United States...

Circular analysis in complex stochastic systems

PubMed Central

Valleriani, Angelo

2015-01-01

Ruling out observations can lead to wrong models. This danger occurs unwillingly when one selects observations, experiments, simulations or time-series based on their outcome. In stochastic processes, conditioning on the future outcome biases all local transition probabilities and makes them consistent with the selected outcome. This circular self-consistency leads to models that are inconsistent with physical reality. It is also the reason why models built solely on macroscopic observations are prone to this fallacy. PMID:26656656

A Study of the Factors and Conditions Associated with Graduate Enrollment Management Practitioners' Participation in Professional Development

ERIC Educational Resources Information Center

Balayan, Ariana

2016-01-01

This investigation was designed to determine the factors and conditions associated with graduate enrollment management practitioners' participation in professional development (PD) activities. The sample consisted of members of a professional association, the National Association of Graduate Admissions Professionals (NAGAP), focused solely on…

Phonological Abstraction in the Mental Lexicon

ERIC Educational Resources Information Center

McQueen, James M.; Cutler, Anne; Norris, Dennis

2006-01-01

A perceptual learning experiment provides evidence that the mental lexicon cannot consist solely of detailed acoustic traces of recognition episodes. In a training lexical decision phase, listeners heard an ambiguous [f-s] fricative sound, replacing either [f] or [s] in words. In a test phase, listeners then made lexical decisions to visual…

Artists Comment on Museum Practices.

ERIC Educational Resources Information Center

Kanatani, Kim; Prabhu, Vas

1996-01-01

Presents three works of art that examine issues of exhibition, display, culture, and access in contemporary museum practices. The works include four black mannequins dressed as security guards, a room-size installation consisting solely of objects related to the artist, and a poster highlighting the general exclusion of women artists. (MJP)

Development of Benthic Indicators for Nearshore Coastal Waters of New Jersey - A REMAP Project

EPA Science Inventory

EPA's National Coastal Assessment (NCA) is providing the first complete, consistent dataset on the condition of benthic communities in the nation's estuaries. Prior to NCA, New Jersey based its evaluation of the ecological condition of its coastal waters solely on dissolved oxyg...

Aiming High: Setting Performance Standards for Student Success

ERIC Educational Resources Information Center

Phillips, Gary; Garcia, Alicia N.

2015-01-01

Content standards, not performance standards, have been almost the sole focus of state policies and recent conversations about academic standards. Without rigorous content and performance standards, we cannot adequately prepare students for the global marketplace. A recent AIR study shows that state performance standards are consistently low and…

CAFE: aCcelerated Alignment-FrEe sequence analysis

PubMed Central

Lu, Yang Young; Tang, Kujin; Ren, Jie; Fuhrman, Jed A.; Waterman, Michael S.

2017-01-01

Abstract Alignment-free genome and metagenome comparisons are increasingly important with the development of next generation sequencing (NGS) technologies. Recently developed state-of-the-art k-mer based alignment-free dissimilarity measures including CVTree, \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$d_2^*$\\end{document} and \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$d_2^S$\\end{document} are more computationally expensive than measures based solely on the k-mer frequencies. Here, we report a standalone software, aCcelerated Alignment-FrEe sequence analysis (CAFE), for efficient calculation of 28 alignment-free dissimilarity measures. CAFE allows for both assembled genome sequences and unassembled NGS shotgun reads as input, and wraps the output in a standard PHYLIP format. In downstream analyses, CAFE can also be used to visualize the pairwise dissimilarity measures, including dendrograms, heatmap, principal coordinate analysis and network display. CAFE serves as a general k-mer based alignment-free analysis platform for studying the relationships among genomes and metagenomes, and is freely available at https://github.com/younglululu/CAFE. PMID:28472388

The A-10 Thunderbolt as an Organic Army Asset

DTIC Science & Technology

1991-06-07

whether report isinterim, final, etc. If Statements on Technical applicable, enter indusive report dates (e.g. 10 Documents." Jun 87 - 30 Jun 88). DOE See...delivered in 1984.31 At present, nearly 650 A-10’s remain in the Air Force inventory. 3 2 As of 30 Septem- ber 1989, the average age of the 447 A-10’s in...designed solely as an armor-defeating CAS aircraft. The aircraft was built around the General Electric GAU-8/A "Avenger," 30 millimeter cannon. The cannon

A re-appraisal of the conventional history of antibiosis and Penicillin.

PubMed

Arseculeratne, S N; Arseculeratne, G

2017-05-01

The popular perception of the history of antibiosis and penicillin is that Alexander Fleming was the sole researcher on penicillin. The literature, however, has documentation of preceding persons who reported definitively on these topics, from the late 19 th century. Divergent reports on "firsts" in the discovery of antimicrobial activity of Penicillium and on the use of penicillin as a therapeutic agent, are present. This review adds knowledge from diverse sources, and restores historical priorities to the conventional story of Penicillin. © 2017 Blackwell Verlag GmbH.

Low-molecular-weight-heparin can benefit women with recurrent pregnancy loss and sole protein S deficiency: a historical control cohort study from Taiwan.

PubMed

Shen, Ming-Ching; Wu, Wan-Ju; Cheng, Po-Jen; Ma, Gwo-Chin; Li, Wen-Chu; Liou, Jui-Der; Chang, Cheng-Shyong; Lin, Wen-Hsiang; Chen, Ming

2016-01-01

Heritable thrombophilias are assumed important etiologies for recurrent pregnancy loss. Unlike in the Caucasian populations, protein S and protein C deficiencies, instead of Factor V Lieden and Prothrombin mutations, are relatively common in the Han Chinese population. In this study we aimed to investigate the therapeutic effect of low molecular weight heparin upon women with recurrent pregnancy loss and documented protein S deficiency. During 2011-2016, 68 women with recurrent pregnancy loss (RPL) and protein S deficiency (both the free antigen and function of protein S were reduced) were initially enrolled. All the women must have experienced at least three recurrent miscarriages. After excluding those carrying balanced translocation, medical condition such as diabetes mellitus, chronic hypertension, and autoimmune disorders (including systemic lupus erythematosus and anti-phospholipid syndrome), coexisting thrombophilias other than persistent protein S deficiency (including transient low protein S level, protein C deficiency, and antithrombin III), only 51 women with RPL and sole protein S deficiency were enrolled. Initially they were prescribed low dose Aspirin (ASA: 100 mg/day) and unfortunately there were still 39 women ended up again with early pregnancy loss (12 livebirths were achieved though). Low-molecular-weight-heparin (LMWH) was given for the 39 women in a dose of 1 mg/Kg every 12 h from the day when the next clinical pregnancy was confirmed to the timing at least 24 h before delivery. The perinatal outcomes were assessed. Of 50 treatment subjects performed for the 39 women (i.e. 11 women enrolled twice for two pregnancies), 46 singletons and one twin achieved livebirths. The successful live-birth rate in the whole series was 94 % (47/50). Nineteen livebirths delivered vaginally whereas 28 delivered by cesarean section. The cesarean delivery rate is thus 59.57 %. Emergent deliveries occurred in 3 but no postpartum hemorrhage had been noted. Our pilot study in Taiwan, an East Asian population, indicated anti-coagulation therapy is of benefit to women with recurrent pregnancy loss who had documented sole protein S deficiency. ISRCTN64574169. Retrospectively registered 29 Jun 2016.

Time Trends of Persistent Organic Pollutants in Benthic and Pelagic Indicator Fishes from Puget Sound, Washington, USA.

PubMed

West, James E; O'Neill, Sandra M; Ylitalo, Gina M

2017-08-01

We modeled temporal trends in polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), and dichlorodiphenyltrichloroethane and its metabolites (DDTs) in two indicator fish species representing benthic and pelagic habitats in Puget Sound, Washington, USA. English sole (Parophrys vetulus, benthic) index sites and larger-scale Pacific herring (Clupea pallasii, pelagic) foraging areas represented a wide range of possible contamination conditions, with sampling locations situated adjacent to watersheds exhibiting high, medium and low development. Consistency in analytical data throughout the study was maintained by either calculating method-bias-correction factors on paired samples as methods evolved or by analyzing older archived samples by current methods. PCBs declined moderately in two herring stocks from a low-development basin (2.3 and 4.0% annual rate of decline) and showed no change in the highly developed and moderately developed basins during a 16- to 21-year period. PCBs increased in English sole from four of ten sites (2.9-7.1%), and the remaining six exhibited no significant change. PBDEs and DDTs declined significantly in all herring stocks (4.2-8.1%), although analytical challenges warrant caution in interpreting DDT results. PBDEs declined in English sole from two high-development and one low-development site (3.7-7.2%) and remained unchanged in the remaining seven. DDTs increased in English sole from one high-development site (Tacoma City Waterway) and declined in two high-development and one low development site. As with herring, analytical challenges warrant caution in interpreting the English sole DDT results. It is likely that source controls and mitigation efforts have contributed to the declines in PBDEs and DDTs overall, whereas PCBs appear to have persisted, especially in the pelagic food web, despite bans in PCB production and use.

17 CFR 230.144A - Private resales of securities to institutions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... assets consist solely of shares of one or more registered investment companies, that have the same... annual financial statements, as of a date not more than 16 months preceding the date of sale under the... securities holdings in its financial statements on the basis of their market value, and no current...

40 CFR 419.34 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

Code of Federal Regulations, 2010 CFR

2010-07-01

... limitations for contaminated runoff. The following effluent limitations constitute the quantity and quality of pollutants or pollutant properties controlled by this paragraph and attributable to contaminated runoff which... point source subject to this subpart. (1) If wastewater consists solely of contaminated runoff and is...

26 CFR 1.638-1 - Continental Shelf areas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... employed by N Corporation as a cook and was physically present on the ship. C's sole duties consisted of...) Examples. The application of the provisions of section 638 and this section may be illustrated by the... physical examinations of L Corporation's employees who are engaged in the exploitation of oil on the...

75 FR 20986 - Permits; Foreign Fishing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-22

.... Comments on this notice may also be submitted by e-mail to [email protected] . Include in the... engage in fishing consisting solely of transporting fish or fish products at sea from a point within the... that state to a point outside the United States. In addition, Public Law 104-297, section 105(e...

26 CFR 26.2654-1 - Certain trusts treated as separate trusts.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Certain trusts treated as separate trusts. 26... 1986 § 26.2654-1 Certain trusts treated as separate trusts. (a) Single trust treated as separate trusts—(1) Substantially separate and independent shares—(i) In general. If a single trust consists solely...

Conceptualising professionalism in occupational therapy through a Western lens.

PubMed

Hordichuk, Chelsea J; Robinson, Allison J; Sullivan, Theresa M

2015-06-01

The term professionalism is embedded within curriculum and occupational therapy documents, yet, explicit discussion of the concept is lacking in the literature. This paper strives for a greater understanding of how professionalism is currently conceptualised within Western occupational therapy literature. A broad literature search was conducted and included international peer-reviewed and grey literature from Western cultures including Australia, Canada, New Zealand, the United Kingdom and the United States. To enrich understanding, some documents from medicine were also included. Professionalism is widely upheld as a core construct of occupational therapy. However, an evidence-based consensus of the specific elements of professionalism guiding occupational therapy practice is lacking. Currently, understanding of professionalism is largely based on multiple, isolated concepts presented in Western professional association documents. Acknowledging the multifaceted and multicultural nature of professionalism is essential to begin systematically delineating and conceptualising elements of professionalism specific to occupational therapy. This review has been conducted from a solely Western cultural lens. Additional work to highlight differences specific to international contexts, cultures, and societal influences is needed to enrich the understanding of professionalism in occupational therapy practice. © 2015 Occupational Therapy Australia.

Information system life-cycle and documentation standards, volume 1

NASA Technical Reports Server (NTRS)

Callender, E. David; Steinbacher, Jody

1989-01-01

The Software Management and Assurance Program (SMAP) Information System Life-Cycle and Documentation Standards Document describes the Version 4 standard information system life-cycle in terms of processes, products, and reviews. The description of the products includes detailed documentation standards. The standards in this document set can be applied to the life-cycle, i.e., to each phase in the system's development, and to the documentation of all NASA information systems. This provides consistency across the agency as well as visibility into the completeness of the information recorded. An information system is software-intensive, but consists of any combination of software, hardware, and operational procedures required to process, store, or transmit data. This document defines a standard life-cycle model and content for associated documentation.

British American Tobacco’s failure in Turkey

PubMed Central

Lawrence, S

2009-01-01

Background and objectives Transnational tobacco companies (TTCs) considered Turkey an important, potential investment market because of its high consumption rates and domestic commitment to tobacco. This paper outlines how British American Tobacco (BAT) attempted to establish a joint venture with the government monopoly TEKEL, while waiting for privatisation and a private tender. Methods Analysis of tobacco industry documents from the Guildford Depository and online tobacco document sources. Results BAT failed to establish a market share in Turkey until 2000 despite repeated attempts to form a joint venture with Turkey’s tobacco monopoly, TEKEL, once the market liberalised in the mid 1980s. Conclusions BAT’s failure in the Turkish market was due to a misguided investment strategy focused solely on acquiring TEKEL and is contrasted with Philip Morris success in Turkey despite both TTCs working within Turkey’s unstable and corrupt investing climate. PMID:18845622

12 CFR 329.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the bank does not reserve the right to require at least seven days' written notice prior to withdrawal...-100 (12 U.S.C. 1832(a)(2)).1 1 Paragraph (1) of 12 U.S.C. 1832(a) authorizes banks to let certain... accounts which consist solely of funds in which the entire beneficial interest is held by one or more...

76 FR 15857 - Injurious Wildlife Species; Listing the Bighead Carp (Hypophthalmichthys nobilis) as Injurious Fish

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-22

... without a permit solely for their own use upon filing a written declaration with the District Director of... and for the purposes of creating a consistent format for the list and helping to ensure clarity... public interest'' standard under the APA to the extent that publication of a proposed rule would likely...

Literature-Based Reading Series for Grades K-3: Are They Truly Literature?

ERIC Educational Resources Information Center

Donoghue, Mildred R.

In its current adoptions of reading series for the elementary grades, California has chosen literature-based programs rather than the more traditional basal readers. A study investigated whether the contents of such readers for grades K-3 truly consist solely of literary selections, since it is well-recognized that quality books carry heavy…

Genetic Variation in Melatonin Pathway Enzymes in Children with Autism Spectrum Disorder and Comorbid Sleep Onset Delay

ERIC Educational Resources Information Center

Veatch, Olivia J.; Pendergast, Julie S.; Allen, Melissa J.; Leu, Roberta M.; Johnson, Carl Hirschie; Elsea, Sarah H.; Malow, Beth A.

2015-01-01

Sleep disruption is common in individuals with autism spectrum disorder (ASD). Genes whose products regulate endogenous melatonin modify sleep patterns and have been implicated in ASD. Genetic factors likely contribute to comorbid expression of sleep disorders in ASD. We studied a clinically unique ASD subgroup, consisting solely of children with…

English Grammar in School Textbooks: Towards a Consistent Linguistic Alternative. Occasional Papers Number 11.

ERIC Educational Resources Information Center

Huddleston, Rodney

This report offers a critique, from a linguistic viewpoint of the approach to grammatical description and prescription found in commonly used Australian school textbooks in 1987. Attention was directed solely towards grammatical content. A review of 41 primary and secondary level texts was conducted. All texts were published in Australia, and all…

Religiousness and Infidelity: Attendance, but not Faith and Prayer, Predict Marital Fidelity

ERIC Educational Resources Information Center

Atkins, David C.; Kessel, Deborah E.

2008-01-01

High religiousness has been consistently linked with a decreased likelihood of past infidelity but has been solely defined by religious service attendance, a limited assessment of a complex facet of life. The current study developed nine religiousness subscales using items from the 1998 General Social Survey to more fully explore the association…

Homo floresiensis Contextualized: A Geometric Morphometric Comparative Analysis of Fossil and Pathological Human Samples

PubMed Central

Baab, Karen L.; McNulty, Kieran P.; Harvati, Katerina

2013-01-01

The origin of hominins found on the remote Indonesian island of Flores remains highly contentious. These specimens may represent a new hominin species, Homo floresiensis, descended from a local population of Homo erectus or from an earlier (pre-H. erectus) migration of a small-bodied and small-brained hominin out of Africa. Alternatively, some workers suggest that some or all of the specimens recovered from Liang Bua are pathological members of a small-bodied modern human population. Pathological conditions proposed to explain their documented anatomical features include microcephaly, myxoedematous endemic hypothyroidism (“cretinism”) and Laron syndrome (primary growth hormone insensitivity). This study evaluates evolutionary and pathological hypotheses through comparative analysis of cranial morphology. Geometric morphometric analyses of landmark data show that the sole Flores cranium (LB1) is clearly distinct from healthy modern humans and from those exhibiting hypothyroidism and Laron syndrome. Modern human microcephalic specimens converge, to some extent, on crania of extinct species of Homo. However in the features that distinguish these two groups, LB1 consistently groups with fossil hominins and is most similar to H. erectus. Our study provides further support for recognizing the Flores hominins as a distinct species, H. floresiensis, whose affinities lie with archaic Homo. PMID:23874886

Multi-element otolith chemistry of juvenile sole ( Solea solea), whiting ( Merlangius merlangus) and European seabass ( Dicentrarchus labrax) in the Thames Estuary and adjacent coastal regions

NASA Astrophysics Data System (ADS)

Leakey, Chris D. B.; Attrill, Martin J.; Fitzsimons, Mark F.

2009-04-01

Estuaries are regarded as valuable nursery habitats for many commercially important marine fishes, potentially providing a thermal resource, refuge from predators and a source of abundant prey. To assess the extent of estuarine use by juvenile (0+) common sole ( Solea solea), whiting ( Merlangius merlangus) and European seabass ( Dicentrarchus labrax) we: (1) developed techniques to distinguish between estuarine and coastally-caught juveniles using otolith chemistry; and (2) examined the accuracy with which multi-elemental signatures could re-classify juveniles to their region of collection. High-resolution solution-based inductively coupled plasma mass spectrometry (HB-SB-ICPMS) was used to quantify 32 elements within the juvenile otoliths; 14 elements occurred above detection limits for all samples. Some elemental distributions demonstrated clear differences between estuarine and coastally-caught fish. Multivariate analysis of the otolith chemistry data resulted in 95-100% re-classification accuracy to the region of collection. Estuarine and coastal signatures were most clearly defined for sole which, compared to bass and whiting, have low mobility and are less likely to move from estuarine to coastal habitats between larval settlement and later migration to adult stocks. Sole were the only species to reveal an energetic benefit associated with an estuarine juvenile phase. The physiological ability of bass to access upper estuarine regions was consistent with some elemental data, while the high mobility and restricted range of whiting resulted in less distinct otolith chemistries.

Characterization of stress coping style in Senegalese sole (Solea senegalensis) juveniles and breeders for aquaculture.

PubMed

Ibarra-Zatarain, Z; Fatsini, E; Rey, S; Chereguini, O; Martin, I; Rasines, I; Alcaraz, C; Duncan, N

2016-11-01

The aim of this work was to characterize stress coping styles of Senegalese sole ( Solea senegalensis ) juveniles and breeders and to select an operational behavioural screening test (OBST) that can be used by the aquaculture industry to classify and select between behavioural phenotypes in order to improve production indicators. A total of 61 juveniles and 59 breeders were subjected to five individual behavioural tests and two grouping tests. At the end of the individual tests, all animals were blood sampled in order to measure cortisol, glucose and lactate. Three tests (restraining, new environment and confinement) characterized the stress coping style behaviour of Senegalese sole juveniles and breeders and demonstrated inter-individual consistency. Further, the tests when incorporated into a principal components analysis (PCA) (i) identified two principal axes of personality traits: 'fearfulness-reactivity' and 'activity-exploration', (ii) were representative of the physiological axis of stress coping style, and (iii) were validated by established group tests. This study proposed for the first time three individual coping style tests that reliably represented proactive and reactive personalities of Senegalese sole juveniles and breeders. In addition, the three proposed tests met some basic operational criteria (rapid testing, no special equipment and easy to apply and interpret) that could prove attractive for fish farmers to identify fish with a specific behaviour that gives advantages in the culture system and that could be used to establish selection-based breeding programmes to improve domestication and production.

Characterization of stress coping style in Senegalese sole (Solea senegalensis) juveniles and breeders for aquaculture

PubMed Central

Fatsini, E.; Rey, S.; Chereguini, O.; Martin, I.; Rasines, I.; Duncan, N.

2016-01-01

The aim of this work was to characterize stress coping styles of Senegalese sole (Solea senegalensis) juveniles and breeders and to select an operational behavioural screening test (OBST) that can be used by the aquaculture industry to classify and select between behavioural phenotypes in order to improve production indicators. A total of 61 juveniles and 59 breeders were subjected to five individual behavioural tests and two grouping tests. At the end of the individual tests, all animals were blood sampled in order to measure cortisol, glucose and lactate. Three tests (restraining, new environment and confinement) characterized the stress coping style behaviour of Senegalese sole juveniles and breeders and demonstrated inter-individual consistency. Further, the tests when incorporated into a principal components analysis (PCA) (i) identified two principal axes of personality traits: ‘fearfulness-reactivity’ and ‘activity-exploration’, (ii) were representative of the physiological axis of stress coping style, and (iii) were validated by established group tests. This study proposed for the first time three individual coping style tests that reliably represented proactive and reactive personalities of Senegalese sole juveniles and breeders. In addition, the three proposed tests met some basic operational criteria (rapid testing, no special equipment and easy to apply and interpret) that could prove attractive for fish farmers to identify fish with a specific behaviour that gives advantages in the culture system and that could be used to establish selection-based breeding programmes to improve domestication and production. PMID:28018634

The GLAS Algorithm Theoretical Basis Document for Precision Attitude Determination (PAD)

NASA Technical Reports Server (NTRS)

Bae, Sungkoo; Smith, Noah; Schutz, Bob E.

2013-01-01

The Geoscience Laser Altimeter System (GLAS) was the sole instrument for NASAs Ice, Cloud and land Elevation Satellite (ICESat) laser altimetry mission. The primary purpose of the ICESat mission was to make ice sheet elevation measurements of the polar regions. Additional goals were to measure the global distribution of clouds and aerosols and to map sea ice, land topography and vegetation. ICESat was the benchmark Earth Observing System (EOS) mission to be used to determine the mass balance of the ice sheets, as well as for providing cloud property information, especially for stratospheric clouds common over polar areas.

TWRS configuration management requirement source document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vann, J.M.

The TWRS Configuration Management (CM) Requirement Source document prescribes CM as a basic product life-cycle function by which work and activities are conducted or accomplished. This document serves as the requirements basis for the TWRS CM program. The objective of the TWRS CM program is to establish consistency among requirements, physical/functional configuration, information, and documentation for TWRS and TWRS products, and to maintain this consistency throughout the life-cycle of TWRS and the product, particularly as changes are being made.

Maize-grain legume intercropping for enhanced resource use efficiency and crop productivity in the Guinea savanna of northern Ghana.

PubMed

Kermah, Michael; Franke, Angelinus C; Adjei-Nsiah, Samuel; Ahiabor, Benjamin D K; Abaidoo, Robert C; Giller, Ken E

2017-11-01

Smallholder farmers in the Guinea savanna practise cereal-legume intercropping to mitigate risks of crop failure in mono-cropping. The productivity of cereal-legume intercrops could be influenced by the spatial arrangement of the intercrops and the soil fertility status. Knowledge on the effect of soil fertility status on intercrop productivity is generally lacking in the Guinea savanna despite the wide variability in soil fertility status in farmers' fields, and the productivity of within-row spatial arrangement of intercrops relative to the distinct-row systems under on-farm conditions has not been studied in the region. We studied effects of maize-legume spatial intercropping patterns and soil fertility status on resource use efficiency, crop productivity and economic profitability under on-farm conditions in the Guinea savanna. Treatments consisted of maize-legume intercropped within-row, 1 row of maize alternated with one row of legume, 2 rows of maize alternated with 2 rows of legume, a sole maize crop and a sole legume crop. These were assessed in the southern Guinea savanna (SGS) and the northern Guinea savanna (NGS) of northern Ghana for two seasons using three fields differing in soil fertility in each agro-ecological zone. Each treatment received 25 kg P and 30 kg K ha -1 at sowing, while maize received 25 kg (intercrop) or 50 kg (sole) N ha -1 at 3 and 6 weeks after sowing. The experiment was conducted in a randomised complete block design with each block of treatments replicated four times per fertility level at each site. Better soil conditions and rainfall in the SGS resulted in 48, 38 and 9% more maize, soybean and groundnut grain yield, respectively produced than in the NGS, while 11% more cowpea grain yield was produced in the NGS. Sole crops of maize and legumes produced significantly more grain yield per unit area than the respective intercrops of maize and legumes. Land equivalent ratios (LERs) of all intercrop patterns were greater than unity indicating more efficient and productive use of environmental resources by intercrops. Sole legumes intercepted more radiation than sole maize, while the interception by intercrops was in between that of sole legumes and sole maize. The intercrop however converted the intercepted radiation more efficiently into grain yield than the sole crops. Economic returns were greater for intercrops than for either sole crop. The within-row intercrop pattern was the most productive and lucrative system. Larger grain yields in the SGS and in fertile fields led to greater economic returns. However, intercropping systems in poorly fertile fields and in the NGS recorded greater LERs (1.16-1.81) compared with fertile fields (1.07-1.54) and with the SGS. This suggests that intercropping is more beneficial in less fertile fields and in more marginal environments such as the NGS. Cowpea and groundnut performed better than soybean when intercropped with maize, though the larger absolute grain yields of soybean resulted in larger net benefits.

50 CFR 18.25 - Exempted marine mammals or marine mammal products.

Code of Federal Regulations, 2012 CFR

2012-10-01

... effective date of the foreign law making the taking or sale, as the case may be, of such marine mammals or... mammals or marine mammal products. (a) The provisions of the Act and these regulations shall not apply: (1... marine mammal portion of such product consists solely of a marine mammal taken before such date. (b) The...

50 CFR 18.25 - Exempted marine mammals or marine mammal products.

Code of Federal Regulations, 2013 CFR

2013-10-01

... effective date of the foreign law making the taking or sale, as the case may be, of such marine mammals or... mammals or marine mammal products. (a) The provisions of the Act and these regulations shall not apply: (1... marine mammal portion of such product consists solely of a marine mammal taken before such date. (b) The...

50 CFR 18.25 - Exempted marine mammals or marine mammal products.

Code of Federal Regulations, 2010 CFR

2010-10-01

... effective date of the foreign law making the taking or sale, as the case may be, of such marine mammals or... mammals or marine mammal products. (a) The provisions of the Act and these regulations shall not apply: (1... marine mammal portion of such product consists solely of a marine mammal taken before such date. (b) The...

50 CFR 18.25 - Exempted marine mammals or marine mammal products.

Code of Federal Regulations, 2011 CFR

2011-10-01

... effective date of the foreign law making the taking or sale, as the case may be, of such marine mammals or... mammals or marine mammal products. (a) The provisions of the Act and these regulations shall not apply: (1... marine mammal portion of such product consists solely of a marine mammal taken before such date. (b) The...

50 CFR 18.25 - Exempted marine mammals or marine mammal products.

Code of Federal Regulations, 2014 CFR

2014-10-01

... effective date of the foreign law making the taking or sale, as the case may be, of such marine mammals or... mammals or marine mammal products. (a) The provisions of the Act and these regulations shall not apply: (1... marine mammal portion of such product consists solely of a marine mammal taken before such date. (b) The...

The Intelligent Anatomy Spotter: A New Approach to Incorporate Higher Levels of Bloom's Taxonomy

ERIC Educational Resources Information Center

Choudhury, Bipasha; Gouldsborough, Ingrid; Shaw, Frances L.

2016-01-01

The spotter test is an assessment that has been used widely to test practical knowledge of anatomy. Traditional spotter formats often focus solely on knowledge recall, in addition to being an onerous marking burden on staff where consistency in marking free text responses can be questioned. First-year optometry students at the University of…

78 FR 61958 - New England Hydropower Company, LLC; Notice of Preliminary Permit Application Accepted for Filing...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-08

... located on Quinnipiac River, near the city of Meriden, in New Haven County, Connecticut. The sole purpose...' express permission. The proposed project would consist of the following: (1) An existing 25-foot-high, 430-foot-long earth embankment dam with four low-level, sluice gates and a 242-foot-long concrete spillway...

78 FR 58534 - White Pine Waterpower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-24

... the town of Ely, White Pine County, Nevada. The sole purpose of a preliminary permit, if issued, is to... consist of the following: (1) An artificially lined, upper reservoir having a capacity of 5,535 acre- feet at 8,550 feet above mean sea level (msl); (2) an artificially lined, lower reservoir having a...

32 CFR 1636.8 - Considerations relevant to granting or denying a claim for classification as a conscientious...

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Considerations relevant to granting or denying a... objection is not solely a matter of expediency. A recent crystallization of beliefs does not in itself... in response to war and weapons which is consistent with his stated beliefs. Instances of violent acts...

32 CFR 1636.8 - Considerations relevant to granting or denying a claim for classification as a conscientious...

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Considerations relevant to granting or denying a... objection is not solely a matter of expediency. A recent crystallization of beliefs does not in itself... in response to war and weapons which is consistent with his stated beliefs. Instances of violent acts...

32 CFR 1636.8 - Considerations relevant to granting or denying a claim for classification as a conscientious...

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Considerations relevant to granting or denying a... objection is not solely a matter of expediency. A recent crystallization of beliefs does not in itself... in response to war and weapons which is consistent with his stated beliefs. Instances of violent acts...

32 CFR 1636.8 - Considerations relevant to granting or denying a claim for classification as a conscientious...

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Considerations relevant to granting or denying a... objection is not solely a matter of expediency. A recent crystallization of beliefs does not in itself... in response to war and weapons which is consistent with his stated beliefs. Instances of violent acts...

32 CFR 1636.8 - Considerations relevant to granting or denying a claim for classification as a conscientious...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Considerations relevant to granting or denying a... objection is not solely a matter of expediency. A recent crystallization of beliefs does not in itself... in response to war and weapons which is consistent with his stated beliefs. Instances of violent acts...

Complete Genome Sequence of Dehalobacterium formicoaceticum Strain DMC, a Strictly Anaerobic Dichloromethane-Degrading Bacterium

DOE PAGES

Chen, Gao; Murdoch, Robert W.; Mack, E. Erin; ...

2017-09-14

Dehalobacterium formicoaceticum utilizes dichloromethane as the sole energy source in defined anoxic bicarbonate-buffered mineral salt medium. The products are formate, acetate, inorganic chloride, and biomass. The bacterium’s genome was sequenced using PacBio, assembled, and annotated. The complete genome consists of one 3.77-Mb circular chromosome harboring 3,935 predicted protein-encoding genes.

Predicting and Projecting Stand Dominant Height From Inventory Data For Young Longleaf Pine Plantations in Southwest Georgia

Treesearch

John R. Brooks

2004-01-01

A stand dominant height prediction technique, based solely on diameter distribution and total height data from standard inventory procedures, was investigated. The data consist of 15 managed longleaf pine (Pinus palustris Mill.) plantations that are part of a growth and yield study located in Worth, Mitchell, and Baker counties in southwest Georgia....

Complete Genome Sequence of Dehalobacterium formicoaceticum Strain DMC, a Strictly Anaerobic Dichloromethane-Degrading Bacterium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Gao; Murdoch, Robert W.; Mack, E. Erin

Dehalobacterium formicoaceticum utilizes dichloromethane as the sole energy source in defined anoxic bicarbonate-buffered mineral salt medium. The products are formate, acetate, inorganic chloride, and biomass. The bacterium’s genome was sequenced using PacBio, assembled, and annotated. The complete genome consists of one 3.77-Mb circular chromosome harboring 3,935 predicted protein-encoding genes.

A Descriptive Study of the Factors Influencing Middle School Choice in a Diverse Magnet School District in Northern New Jersey

ERIC Educational Resources Information Center

Anemone, Alex

2008-01-01

Since their creation over two centuries ago, public schools have been coupled with students via geographical zones. Bolstered by compulsory attendance laws, public schools have a very consistent clientele. Based solely on where they resided, students were required to attend specific schools between Kindergarten and Grade 12. Schools have, in…

50 CFR 403.04 - Determinations and hearings under section 109(c) of the MMPA.

Code of Federal Regulations, 2010 CFR

2010-10-01

... management program the state must provide for a process, consistent with section 109(c) of the Act, to... must include the elements set forth below. (b) Basis, purpose, and scope. The process set forth in this... made solely on the basis of the record developed at the hearing. The state agency in making its final...

Food sharing in vampire bats: reciprocal help predicts donations more than relatedness or harassment

PubMed Central

Carter, Gerald G.; Wilkinson, Gerald S.

2013-01-01

Common vampire bats often regurgitate food to roost-mates that fail to feed. The original explanation for this costly helping behaviour invoked both direct and indirect fitness benefits. Several authors have since suggested that food sharing is maintained solely by indirect fitness because non-kin food sharing could have resulted from kin recognition errors, indiscriminate altruism within groups, or harassment. To test these alternatives, we examined predictors of food-sharing decisions under controlled conditions of mixed relatedness and equal familiarity. Over a 2 year period, we individually fasted 20 vampire bats (Desmodus rotundus) and induced food sharing on 48 days. Surprisingly, donors initiated food sharing more often than recipients, which is inconsistent with harassment. Food received was the best predictor of food given across dyads, and 8.5 times more important than relatedness. Sixty-four per cent of sharing dyads were unrelated, approaching the 67 per cent expected if nepotism was absent. Consistent with social bonding, the food-sharing network was consistent and correlated with mutual allogrooming. Together with past work, these findings support the hypothesis that food sharing in vampire bats provides mutual direct fitness benefits, and is not explained solely by kin selection or harassment. PMID:23282995

Food sharing in vampire bats: reciprocal help predicts donations more than relatedness or harassment.

PubMed

Carter, Gerald G; Wilkinson, Gerald S

2013-02-22

Common vampire bats often regurgitate food to roost-mates that fail to feed. The original explanation for this costly helping behaviour invoked both direct and indirect fitness benefits. Several authors have since suggested that food sharing is maintained solely by indirect fitness because non-kin food sharing could have resulted from kin recognition errors, indiscriminate altruism within groups, or harassment. To test these alternatives, we examined predictors of food-sharing decisions under controlled conditions of mixed relatedness and equal familiarity. Over a 2 year period, we individually fasted 20 vampire bats (Desmodus rotundus) and induced food sharing on 48 days. Surprisingly, donors initiated food sharing more often than recipients, which is inconsistent with harassment. Food received was the best predictor of food given across dyads, and 8.5 times more important than relatedness. Sixty-four per cent of sharing dyads were unrelated, approaching the 67 per cent expected if nepotism was absent. Consistent with social bonding, the food-sharing network was consistent and correlated with mutual allogrooming. Together with past work, these findings support the hypothesis that food sharing in vampire bats provides mutual direct fitness benefits, and is not explained solely by kin selection or harassment.

Workbook for the Codification of State Statutes and Regulations

EPA Pesticide Factsheets

The Codification Workbook package consists of two documents. The first is this document -- the Codification Workbook which contains information and instructions for codification. The second document is the Appendix containing the supporting documents.

An Application of the Phosphorus Consistent Rule for Environmentally Acceptable Cost-Efficient Management of Broiler Litter in Crop Production

NASA Technical Reports Server (NTRS)

Paudel, Krishna P.; Limaye, Ashutosh; Adhikari, Murali; Martin, Neil R., Jr.

2004-01-01

We calculated the profitability of using broiler litter as a source of plant nutrients using the phosphorus consistent litter application rule. The cost saving by using litter is 37% over the use of chemical fertilizer-only option to meet the nutrient needs of major crops grown in Alabama. In the optimal solution, only a few routes of all the possible routes developed were used for inter- and intra- county litter hauling. If litter is not adopted as the sole source of crop nutrients, the best environmental policy may be to pair the phosphorus consistent rule with taxes, marketable permits, and subsidies.flaws

Testing a Nursing-Specific Model of Electronic Patient Record documentation with regard to information completeness, comprehensiveness and consistency.

PubMed

von Krogh, Gunn; Nåden, Dagfinn; Aasland, Olaf Gjerløw

2012-10-01

To present the results from the test site application of the documentation model KPO (quality assurance, problem solving and caring) designed to impact the quality of nursing information in electronic patient record (EPR). The KPO model was developed by means of consensus group and clinical testing. Four documentation arenas and eight content categories, nursing terminologies and a decision-support system were designed to impact the completeness, comprehensiveness and consistency of nursing information. The testing was performed in a pre-test/post-test time series design, three times at a one-year interval. Content analysis of nursing documentation was accomplished through the identification, interpretation and coding of information units. Data from the pre-test and post-test 2 were subjected to statistical analyses. To estimate the differences, paired t-tests were used. At post-test 2, the information is found to be more complete, comprehensive and consistent than at pre-test. The findings indicate that documentation arenas combining work flow and content categories deduced from theories on nursing practice can influence the quality of nursing information. The KPO model can be used as guide when shifting from paper-based to electronic-based nursing documentation with the aim of obtaining complete, comprehensive and consistent nursing information. © 2012 Blackwell Publishing Ltd.

Effectively dealing with state and federal regulators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zebrowski, S.M.

1997-08-01

Environmental compliance is an essential part of every business practice in today`s world. For almost a quarter of a century, the nation has been involved in environmental restoration of contaminated sites. Over the years, the science and engineering required to remediate these sites has been developed and well documented. However, there is one major part of the environmental cleanup business that still alludes much of the regulated community. Communication skills required for successful project execution have not been well studied or documented. It is only in retrospect that man can look back on experiences and learn, then document how onemore » can better communicate with the regulators and stakeholders for future environmental compliance and cleanup work. The intent of this paper is to present the management skills learned from past experiences that would facilitate the effective communications between the regulated community, regulators and stakeholders during site remediation. Lessons learned from the past demonstrate that sometimes remediations are driven not solely by engineering and science, but also in part by emotions and politics. Other lessons demonstrate that communications with the regulators and stakeholders should begin very early in the remediation process.« less

The quest for universality: reflections on the Universal Draft Declaration on Bioethics and Human Rights.

PubMed

Rawlinson, Mary C; Donchin, Anne

2005-09-01

This essay focuses on two underlying presumptions that impinge on the effort of UNESCO to engender universal agreement on a set of bioethical norms: the conception of universality that pervades much of the document, and its disregard of structural inequalities that significantly impact health. Drawing on other UN system documents and recent feminist bioethics scholarship, we argue that the formulation of universal principles should not rely solely on shared ethical values, as the draft document affirms, but also on differences in ethical values that obtain across cultures. UNESCO's earlier work on gender mainstreaming illustrates the necessity of thinking from multiple perspectives in generating universal norms. The declaration asserts the 'fundamental equality of all human beings in dignity and rights'(1) and insists that 'the highest attainable standard of health is one of the fundamental rights of every human being without distinction of race, religion, political belief, economic or social condition'(2) yet it does not explicitly recognize disparities of power and wealth that deny equal dignity and rights to many. Without attention to structural (as opposed to merely accidental) inequities, UNESCO's invocation of rights is so abstract as to be incompatible with its avowed intention.

Contributions of processed foods to dietary intake in the US from 2003-2008: a report of the Food and Nutrition Science Solutions Joint Task Force of the Academy of Nutrition and Dietetics, American Society for Nutrition, Institute of Food Technologists, and International Food Information Council.

PubMed

Eicher-Miller, Heather A; Fulgoni, Victor L; Keast, Debra R

2012-11-01

Processed foods are an integral part of American diets, but a comparison of the nutrient contribution of foods by level of processing with the recommendations of the Dietary Guidelines for Americans regarding nutrients to encourage or to reduce has not been documented. The mean reported daily dietary intakes of these nutrients and other components were examined among 25,351 participants ≥2 y of age in the 2003-2008 NHANES to determine the contribution of processed food to total intakes. Also examined was the percent contribution of each nutrient to the total reported daily nutrient intake for each of the 5 categories of food that were defined by the level of processing. All processing levels contributed to nutrient intakes, and none of the levels contributed solely to nutrients to be encouraged or solely to food components to be reduced. The processing level was a minor determinant of individual foods' nutrient contribution to the diet and, therefore, should not be a primary factor when selecting a balanced diet.

75 FR 27548 - White Pine Waterpower, LLC; Notice of Preliminary Permit Application Accepted For Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-17

..., Nevada, near the town of Ely. The sole purpose of a preliminary permit, if issued, is to grant the permit... consist of the following: (1) A 210-foot-high upper, rockfill dam; (2) an upper artificial, lined reservoir with a surface area of about 74 acres and volume of approximately 4,938 acre-feet at normal water...

76 FR 77996 - FFP Project 9 LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-15

... Water Supply District, located on the Pearl River, in Rankin and Hinds Counties, Mississippi. The sole...' express permission. The proposed project would consist of: (1) A 23,400-foot-long, 64- foot-high earthen dam; (2) a reservoir with a surface area of 32,000 acres and a storage capacity of 341,000 acre-feet...

Towards A Possible Therapy for Diabetes Complications

DTIC Science & Technology

2014-12-01

Towards A Possible Therapy for Diabetes Complications PRINCIPAL INVESTIGATOR: Massimo Trucco, M.D...September 2014 4. TITLE AND SUBTITLE Towards A Possible Therapy for Diabetes Complications 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-10-1-1055...of the beta cells. Consistently with this view, the standard of care for diabetic , and especially T1D patients is solely insulin-replacement therapy

Mathematics Student Teachers' Epistemological Beliefs about the Nature of Mathematics and the Goals of Mathematics Teaching and Learning in the Beginning of Their Studies

ERIC Educational Resources Information Center

Viholainen, Antti; Asikainen, Mervi; Hirvonen, Pekka E.

2014-01-01

This article examines Finnish mathematics student teachers' epistemological beliefs concerning the nature of mathematics and the goals of mathematics teaching and learning solely in the beginning of their studies at university. A total of 18 students participated in a study consisting of a short questionnaire and interviews. The data was analyzed…

Conversion of atrial fibrillation after levothyroxine in a dog with hypothyroidism and arterial thromboembolism.

PubMed

Chow, B; French, A

2014-05-01

A six-year-old female spayed mixed-breed dog was referred following a 3-week history of lameness and progressive neurological deficits in both hindlimbs, and a 1-week history of a cardiac arrhythmia. The dog was diagnosed with hypothyroidism, atrial fibrillation, myocardial dysfunction and arterial thromboembolism. Cardioversion occurred after 2 weeks of levothyroxine supplementation, with improved systolic function over time. To the authors' knowledge, this is the first case reported in the veterinary or human literature documenting hypothyroidism with persistent atrial fibrillation being converted to sinus rhythm with levothyroxine as sole therapy. © 2014 British Small Animal Veterinary Association.

An Ectopic Case of Tunga spp. Infection in Peru

PubMed Central

Maco, Vicente; Maco, Vicente P.; Gotuzzo, Eduardo

2010-01-01

Tungiasis is a neglected ectoparasitism of impoverished areas in South America and sub-Saharan Africa. The sand flea Tunga spp. preferably infests the soles and the periungueal and interdigital regions of the feet. Ectopic tungiasis is rare, even in highly endemic areas. We describe a case of an indigenous patient in Peru who presented with a nodular lesion in the extensor aspect of the knee and whose biopsy was compatible with Tunga spp. This is the first documented case of knee tungiasis in an endemic country. The historical, clinical, histological, and current epidemiological aspects of tungiasis in Peru are discussed here. PMID:20519602

Model-Based Systems

NASA Technical Reports Server (NTRS)

Frisch, Harold P.

2007-01-01

Engineers, who design systems using text specification documents, focus their work upon the completed system to meet Performance, time and budget goals. Consistency and integrity is difficult to maintain within text documents for a single complex system and more difficult to maintain as several systems are combined into higher-level systems, are maintained over decades, and evolve technically and in performance through updates. This system design approach frequently results in major changes during the system integration and test phase, and in time and budget overruns. Engineers who build system specification documents within a model-based systems environment go a step further and aggregate all of the data. They interrelate all of the data to insure consistency and integrity. After the model is constructed, the various system specification documents are prepared, all from the same database. The consistency and integrity of the model is assured, therefore the consistency and integrity of the various specification documents is insured. This article attempts to define model-based systems relative to such an environment. The intent is to expose the complexity of the enabling problem by outlining what is needed, why it is needed and how needs are being addressed by international standards writing teams.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doebrich, J.L.; Murchey, B.L.; Theodore, T.G.

Recently completed 1:24,000-scale geologic mapping and biostratigraphic studies of the Mississippian, Pennsylvanian, and Permian Havallah sequence in the Valmy, North Peak, and Antler Peak quadrangles of the Battle Mountain area have documented a significant amount of imbricate thrusting in the Golconda allochthon (GA) and defined depositional environments that existed in the Havallah basin. Furthermore, the Willow Creek thrust (WCT) is identified as a major N-striking W-dipping structure, fairly continuous through the quadrangles, that tectonically subdivides the allochthon into two lithotectonic units. Pennsylvanian and Permian slope deposits comprise lithotectonic unit 1 (LT1), the footwall of the WCT. LT1 consists of amore » coarsening upward sequence of sponge-spicule chert and argillite, and cherty shale, which are tectonically cut out near Trenton Canyon such that the WCT becomes the sole of the GA. Mississippian basin deposits and Pennsylvanian and Permian turbidites comprise lithotectonic unit 2 (LT2), the hanging wall of the WCT. LT2 consists of a coarsening and shallowing upward sequence of Mississippian radiolarian chert and shale, overlain by Pennsylvanian and Permian calcareous siltstone and sandstone, pebble conglomerate, and pebbly to micritic limestone. Oncolitic coatings on fossil fragments in some calcareous sands high in the stacking pattern suggest environments as shallow as 20 m. Most modes of quartz- and calcite-framework dominant sands plot in quartzose recycled orogen fields; however, compositional facies with abundant chert fragments are rare in contrast with quartz-chert petrofacies sands reported for the GA in the Mount Tobin area. Extrabasinal carbonate grains at framework sites may have been derived from elevated fault blocks or platforms west of the Antler highlands. These studies confirm that turbiditic rocks in the GA show ample evidence in their provenance for having attachments to a nearby continental margin.« less

Global Surface Dust Distribution Changes on Mars (MY24-33)

NASA Astrophysics Data System (ADS)

Piqueux, S.; Hayne, P. O.; Kleinboehl, A.; Edwards, C. S.; Elder, C. M.; Heavens, N. G.; Kass, D. M.; McCleese, D. J.; Schofield, J. T.; Shirley, J. H.; Smith, M. D.

2016-12-01

Telescopic and spacecraft observations document inter-annual and inter-seasonal changes of the Martian albedo that are interpreted to result from the redistribution of surface dust in response to atmospheric events such as global or regional dust storms, dust devil activity, or seasonal winds. Based on these observations and general circulation modeling, several authors have hypothesized that a necessary condition for global dust storm initiation and growth is the presence of strategically located surface dust reservoirs replenished during inter-storm periods. If this hypothesis is valid, the cyclical accumulation and removal of thermally thick (>50 μm) layers of dust at specific locations ought to produce a distinct temperature signature, since Martian dust exhibits extremely low thermal conductivity and thermal inertia values compared to sand, gravel, rocks, and bedrock. Characterizing dust movement using temperature data presents a major advantage over mapping relying solely on albedo changes: it yields dust layer thicknesses, whose spatial and temporal integration enables the derivation of surface dust fluxes. In this work, we use global (1° per pixel resolution) seasonal (10° Ls resolution, from MY24 to 33) maps of the Martian surface albedo, atmospheric dust opacity, and ground temperature (derived from TES, THEMIS, and MCS observations) to derive apparent variations of the thermal inertia, and thereby characterize surface changes consistent with the deposition or removal of dust. We show that changes in thermal inertia for some regions are consistent with dust accumulation; whereas others seem to lose dust. We compare these maps with published GCM dust lifting predictions, and with observations of past dust storm occurrence, thereby constraining the role of surface dust availability.

X-ray computed tomography for additive manufacturing: a review

NASA Astrophysics Data System (ADS)

Thompson, A.; Maskery, I.; Leach, R. K.

2016-07-01

In this review, the use of x-ray computed tomography (XCT) is examined, identifying the requirement for volumetric dimensional measurements in industrial verification of additively manufactured (AM) parts. The XCT technology and AM processes are summarised, and their historical use is documented. The use of XCT and AM as tools for medical reverse engineering is discussed, and the transition of XCT from a tool used solely for imaging to a vital metrological instrument is documented. The current states of the combined technologies are then examined in detail, separated into porosity measurements and general dimensional measurements. In the conclusions of this review, the limitation of resolution on improvement of porosity measurements and the lack of research regarding the measurement of surface texture are identified as the primary barriers to ongoing adoption of XCT in AM. The limitations of both AM and XCT regarding slow speeds and high costs, when compared to other manufacturing and measurement techniques, are also noted as general barriers to continued adoption of XCT and AM.

The VELVET A Orthologue VEL1 of Trichoderma reesei Regulates Fungal Development and Is Essential for Cellulase Gene Expression

PubMed Central

Atanasova, Lea; Fekete, Erzsébet; Paholcsek, Melinda; Sándor, Erzsébet; Aquino, Benigno; Druzhinina, Irina S.; Karaffa, Levente; Kubicek, Christian P.

2014-01-01

Trichoderma reesei is the industrial producer of cellulases and hemicellulases for biorefinery processes. Their expression is obligatorily dependent on the function of the protein methyltransferase LAE1. The Aspergillus nidulans orthologue of LAE1 - LaeA - is part of the VELVET protein complex consisting of LaeA, VeA and VelB that regulates secondary metabolism and sexual as well as asexual reproduction. Here we have therefore investigated the function of VEL1, the T. reesei orthologue of A. nidulans VeA. Deletion of the T. reesei vel1 locus causes a complete and light-independent loss of conidiation, and impairs formation of perithecia. Deletion of vel1 also alters hyphal morphology towards hyperbranching and formation of thicker filaments, and with consequently reduced growth rates. Growth on lactose as a sole carbon source, however, is even more strongly reduced and growth on cellulose as a sole carbon source eliminated. Consistent with these findings, deletion of vel1 completely impaired the expression of cellulases, xylanases and the cellulase regulator XYR1 on lactose as a cellulase inducing carbon source, but also in resting mycelia with sophorose as inducer. Our data show that in T. reesei VEL1 controls sexual and asexual development, and this effect is independent of light. VEL1 is also essential for cellulase gene expression, which is consistent with the assumption that their regulation by LAE1 occurs by the VELVET complex. PMID:25386652

Highly Efficient TADF Polymer Electroluminescence with Reduced Efficiency Roll-off via Interfacial Exciplex Host Strategy.

PubMed

Lin, Xingdong; Zhu, Yunhui; Zhang, Baohua; Zhao, Xiaofei; Yao, Bing; Cheng, Yanxiang; Li, Zhanguo; Qu, Yi; Xie, Zhiyuan

2018-01-10

Solution-processed organic light-emitting diodes (s-OLED) consisting of TAPC/TmPyPB interfacial exciplex host and polymer PAPTC TADF emitter are prepared, simultaneously displaying ultralow voltages (2.50/2.91/3.51/4.91 V at luminance of 1/100/1000/1000 cd m -2 ), high efficiencies (14.9%, 50.1 lm W -1 ), and extremely low roll-off rates (J 50 of 63.16 mA cm -2 , L 50 of ca. 15000 cd m -2 ). Such performance is distinctly higher than that of pure-PAPTC s-OLED. Compared to pure-PAPTC, the advanced emissive layer structure of TAPC:PAPTC/TmPyPB is unique in much higher PL quantum yield (79.5 vs 36.3%) and nearly 4-fold enhancement in k RISC of the PAPTC emitter to 1.48 × 10 7 s -1 .

Fine structure constant and quantized optical transparency of plasmonic nanoarrays.

PubMed

Kravets, V G; Schedin, F; Grigorenko, A N

2012-01-24

Optics is renowned for displaying quantum phenomena. Indeed, studies of emission and absorption lines, the photoelectric effect and blackbody radiation helped to build the foundations of quantum mechanics. Nevertheless, it came as a surprise that the visible transparency of suspended graphene is determined solely by the fine structure constant, as this kind of universality had been previously reserved only for quantized resistance and flux quanta in superconductors. Here we describe a plasmonic system in which relative optical transparency is determined solely by the fine structure constant. The system consists of a regular array of gold nanoparticles fabricated on a thin metallic sublayer. We show that its relative transparency can be quantized in the near-infrared, which we attribute to the quantized contact resistance between the nanoparticles and the metallic sublayer. Our results open new possibilities in the exploration of universal dynamic conductance in plasmonic nanooptics.

Tectonic Evolution of the Careón Ophiolite (Northwest Spain): A Remnant of Oceanic Lithosphere in the Variscan Belt.

PubMed

Díaz García F; Arenas; Martínez Catalán JR; González del Tánago J; Dunning

1999-09-01

Analysis of the Careón Unit in the Ordenes Complex (northwest Iberian Massif) has supplied relevant data concerning the existence of a Paleozoic oceanic lithosphere, probably related to the Rheic realm, and the early subduction-related events that were obscured along much of the Variscan belt by subsequent collision tectonics. The ophiolite consists of serpentinized harzburgite and dunite in the lower section and a crustal section made up of coarse-grained and pegmatitic gabbros. An Early Devonian zircon age (395+/-2 Ma, U-Pb) was obtained in a leucocratic gabbro. The whole section was intruded by numerous diabasic gabbro dikes. Convergence processes took place shortly afterward, giving rise to a mantle-rooted synthetic thrust system, with some coeval igneous activity. Garnet amphibolite, developed in metamorphic soles, was found discontinuously attached to the thrust fault. The soles graded downward to epidote-amphibolite facies metabasite and were partially retrogressed to greenschist facies conditions. Thermobarometric estimations carried out at a metamorphic sole (T approximately 650 degrees C; P approximately 11.5 kbar) suggested that imbrications developed in a subduction setting, and regional geology places this subduction in the context of an early Variscan accretionary wedge. Subduction and imbrication of oceanic lithosphere was followed by underthrusting of the Gondwana continental margin.

Market Analysis and Consumer Impacts Source Document. Part III. Consumer Behavior and Attitudes Toward Fuel Efficient Vehicles

DOT National Transportation Integrated Search

1980-12-01

This source document on motor vehicle market analysis and consumer impacts consists of three parts. Part III consists of studies and reviews on: consumer awareness of fuel efficiency issues; consumer acceptance of fuel efficient vehicles; car size ch...

Implementing personal digital assistant documentation of pharmacist interventions in a military treatment facility.

PubMed

Ford, Stephen; Illich, Stan; Smith, Lisa; Franklin, Arthur

2006-01-01

To describe the use of personal digital assistants (PDAs) in documenting pharmacists' clinical interventions. Evans Army Community Hospital (EACH), a 78-bed military treatment facility, in Colorado Springs. Pharmacists on staff at EACH. All pharmacists at EACH used PDAs with the pilot software to record interventions for 1 month. The program underwent final design changes and then became the sole source for recording pharmacist interventions. The results of this project are being evaluated every 3 months for the first year and yearly thereafter. Visual CE (Syware Inc. Cambridge, Mass.) software was selected to develop fields for the documentation tool. This software is simple and easy to use, and users can retrieve reports of interventions from both inpatient and outpatient sections. The software needed to be designed so that data entry would only take a few minutes and ad hoc reports could be produced easily. Number of pharmacist interventions reported, time spent in clinical interventions, and outcome of clinical intervention. Implementing a PDA-based system for documenting pharmacist interventions across ambulatory, inpatient, and clinical services dramatically increased reporting during the first 6 months after implementation (August 2004-February 2005). After initial fielding, clinical pharmacists in advanced practice settings (such as disease management clinic, anticoagulation clinic) recognized a need to tailor the program to their specific activities, which resulted in a spin-off program unique to their practice roles. A PDA-based system for documenting clinical interventions at a military treatment facility increased reporting of interventions across all pharmacy points of service. Pharmacy leadership used these data to document the impact of pharmacist interventions on safety and quality of pharmaceutical care provided.

AEDT Software Requirements Documents - Draft

DOT National Transportation Integrated Search

2007-01-25

This software requirements document serves as the basis for designing and testing the Aviation Environmental Design Tool (AEDT) software. The intended audience for this document consists of the following groups: the AEDT designers, developers, and te...

Effects of Indoor Footwear on Balance and Gait Patterns in Community-Dwelling Older Women.

PubMed

Menz, Hylton B; Auhl, Maria; Munteanu, Shannon E

2017-01-01

Footwear worn indoors is generally less supportive than outdoor footwear and may increase the risk of falls. To evaluate balance ability and gait patterns in older women while wearing different styles of indoor footwear: a backless slipper and an enclosed slipper designed to optimise balance. Older women (n = 30) aged 65-83 years (mean 74.4, SD 5.6) performed a series of laboratory tests of balance ability (postural sway, limits of stability, and tandem walking, measured with the NeuroCom® Balance Master) and gait patterns (walking speed, cadence, and step length, measured with the GAITRite® walkway) while wearing (1) socks, (2) backless slippers with a soft sole, and (3) enclosed slippers with a firm sole and Velcro® fastening. Perceptions of the footwear were also documented using a structured questionnaire. Significant overall effects of footwear were observed for postural sway, the limits of stability test (directional control), the tandem walk test (step width and end sway), and temporospatial gait patterns (walking speed, cadence, and step length). No footwear effects were observed for maximum excursion when performing the limits of stability test or for speed when performing the tandem walk test. Post hoc tests indicated that performances were best while wearing the enclosed slippers, intermediate with socks, and worst with backless slippers. The enclosed slippers were perceived to be more attractive, comfortable, and well fitted, but heavier than the backless slippers. Most participants (n = 23; 77%) reported that they would consider wearing the enclosed slippers to reduce their risk of falling. Indoor footwear with an enclosed heel, Velcro® fastening, and a firm sole optimises balance and gait compared to backless slippers, and is therefore recommended to reduce the risk of falling. © 2016 The Author(s) Published by S. Karger AG, Basel.

Toward increased autonomy in the surgical OR: needs, requests, and expectations.

PubMed

Kranzfelder, Michael; Staub, Christoph; Fiolka, Adam; Schneider, Armin; Gillen, Sonja; Wilhelm, Dirk; Friess, Helmut; Knoll, Alois; Feussner, Hubertus

2013-05-01

The current trend in surgery toward further trauma reduction inevitably leads to increased technological complexity. It must be assumed that this situation will not stay under the sole control of surgeons; mechanical systems will assist them. Certain segments of the work flow will likely have to be taken over by a machine in an automatized or autonomous mode. In addition to the analysis of our own surgical practice, a literature search of the Medline database was performed to identify important aspects, methods, and technologies for increased operating room (OR) autonomy. Robotic surgical systems can help to increase OR autonomy by camera control, application of intelligent instruments, and even accomplishment of automated surgical procedures. However, the important step from simple task execution to autonomous decision making is difficult to realize. Another important aspect is the adaption of the general technical OR environment. This includes adaptive OR setting and context-adaptive interfaces, automated tool arrangement, and optimal visualization. Finally, integration of peri- and intraoperative data consisting of electronic patient record, OR documentation and logistics, medical imaging, and patient surveillance data could increase autonomy. To gain autonomy in the OR, a variety of assistance systems and methodologies need to be incorporated that endorse the surgeon autonomously as a first step toward the vision of cognitive surgery. Thus, we require establishment of model-based surgery and integration of procedural tasks. Structured knowledge is therefore indispensable.

Psi experiments: do the best parapsychological experiments justify the claims for psi?

PubMed

Hyman, R

1988-04-15

Since the founding of the Society of Psychical Research in 1982, psychical researchers have, in each generation, generated research reports which they believed justified the existence of paranormal phenomena. Throughout this period the scientific establishment has either rejected or ignored such claims. The parapsychologists, with some justification, complained that their claims were being rejected without the benefit of a fair hearing. This paper asks the question of how well the best contemporary evidence for psi--the term used to designate ESP and psychokinetic phenomena--stands up to fair and unbiased appraisal. The results of the scrutiny of the three most widely heralded programs of research--the remote viewing experiments, the psi ganzfeld research, and the work with random number generators--indicates that parapsychological research falls short of the professed standards of the field. In particular, the available reports indicate that randomization is often inadequate, multiple statistical testing without adjustment for significance levels is prevalent, possibilities for sensory leakage are not uniformly prevented, errors in use of statistical tests are much too common, and documentation is typically inadequate. Although the responsible critic cannot argue that these observed departures from optimal experimental procedures have been the sole cause of the reported findings, it is reasonable to demand that the parapsychologists produce consistently significant findings from experiments that are methodologically adequate before their claims are taken seriously.

Iron prophylaxis in pregnancy--general or individual and in which dose?

PubMed

Milman, Nils

2006-12-01

Iron is mandatory for normal fetal development, including the brain. Iron deficiency may have deleterious effects for intelligence and behavioral development. It is important to prevent iron deficiency in the fetus by preventing iron deficiency in the pregnant woman. Iron deficiency anemia during pregnancy is a risk factor for preterm delivery and low birth weight. In the Western countries there is no consensus on iron prophylaxis to pregnant women. An adequate iron balance during pregnancy implies body iron reserves of >or=500 mg at conception. The physiologic iron requirements in the second half of gestation cannot be fulfilled solely through dietary iron. Iron supplements during gestation consistently increase serum ferritin and hemoglobin and reduce the prevalence of iron deficiency anemia. Iron has a negative influence on absorption of other divalent metals and increases oxidative stress in pregnancy, for which reason minimum effective iron dose should be advised. From a physiologic point of view, individual iron prophylaxis according to serum ferritin concentration should be preferred to general prophylaxis. Suggested guidelines are (1) ferritin>70 microg/l: no iron supplements; (2) ferritin 30-70 microg/l: 40 mg ferrous iron daily; and (3) ferritin<30 microg/l: 80-100 mg ferrous iron daily. In controlled studies, there are no documented side effects of iron supplements below 100 mg/day. Iron supplements should be taken at bedtime or between meals to ensure optimum absorption.

The structure and dynamics of interactive documents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rocha, J.T.

1999-04-01

Advances in information technology continue to accelerate as the new millennium approaches. With these advances, electronic information management is becoming increasingly important and is now supported by a seemingly bewildering array of hardware and software whose sole purpose is the design and implementation of interactive documents employing multimedia applications. Multimedia memory and storage applications such as Compact Disk-Read Only Memory (CD-ROMs) are already a familiar interactive tool in both the entertainment and business sectors. Even home enthusiasts now have the means at their disposal to design and produce CD-ROMs. More recently, Digital Video Disk (DVD) technology is carving its ownmore » niche in these markets and may (once application bugs are corrected and prices are lowered) eventually supplant CD-ROM technology. CD-ROM and DVD are not the only memory and storage applications capable of supporting interactive media. External, high-capacity drives and disks such as the Iomega{copyright} zip{reg_sign} and jaz{reg_sign} are also useful platforms for launching interactive documents without the need for additional hardware such as CD-ROM burners and copiers. The main drawback here, however, is the relatively high unit price per disk when compared to the unit cost of CD-ROMs. Regardless of the application chosen, there are fundamental structural characteristics that must be considered before effective interactive documents can be created. Additionally, the dynamics of interactive documents employing hypertext links are unique and bear only slight resemblance to those of their traditional hard-copy counterparts. These two considerations form the essential content of this paper.« less

Splinter Protection for Airbase Firefighting Resources

DTIC Science & Technology

1989-12-01

shotcrete) arch structure. The system was developed by Earth Systems, Inc. (ESI) of Durango , Colorado . The concept consists of the reinforced concrete floor...by ESI of Durango , Colorado . Appendix B presents a portion of the ESI construction manual that is supplied with their structural kit. Only the portion...Construction Manual for Shotcrete Arch Structure is copyrightea; it is the sole property of SEARTH SYSTEMS, INC., P.U. box 3270, Durango , Colorado . The

Specifying Software Behavior for Requirements and Design

DTIC Science & Technology

2013-01-01

e.g., Behavior Hiding is comprised of the Function Driver and Shared Services modules. Blacked-out modules, which are concerned with mechanisms for...and Shared Services modules. “The Func- tion Driver Module consists of a set of modules called Func- tion Drivers; each Function Driver is the sole...system environment. Functions that capture the rules determining these output values specify that behavior. The Shared Services module concerns aspects of

The Use of a Learning Management System (LMS) to Serve as the Virtual Common Space of a Network for the Scholarship of Teaching and Learning (SoTL) in an Academic Department

ERIC Educational Resources Information Center

Bradley, Nicolette; Jadeski, Lorraine; Newton, Genevieve; Ritchie, Kerry; Merrett, Scott; Bettger, William

2013-01-01

Traditionally, undergraduate curriculum committees, consisting of appointed faculty and student representatives, have served as the sole departmental vehicle for investigating, discussing and promoting the scholarship of teaching and learning (SoTL) within an academic department. However, with the universal demand for greater accountability on all…

Guest authorship and ghostwriting in publications related to rofecoxib: a case study of industry documents from rofecoxib litigation.

PubMed

Ross, Joseph S; Hill, Kevin P; Egilman, David S; Krumholz, Harlan M

2008-04-16

Authorship in biomedical publication provides recognition and establishes accountability and responsibility. Recent litigation related to rofecoxib provided a unique opportunity to examine guest authorship and ghostwriting, practices that have been suspected in biomedical publication but for which there is little documentation. To characterize different types and the extent of guest authorship and ghostwriting in 1 case study. Court documents originally obtained during litigation related to rofecoxib against Merck & Co Inc. Documents were created predominantly between 1996 and 2004. In addition, publicly available articles related to rofecoxib identified via MEDLINE. All documents were reviewed by one author, with selected review by coauthors, using an iterative process of review, discussion, and rereview of documents to identify information related to guest authorship or ghostwriting. Approximately 250 documents were relevant to our review. For the publication of clinical trials, documents were found describing Merck employees working either independently or in collaboration with medical publishing companies to prepare manuscripts and subsequently recruiting external, academically affiliated investigators to be authors. Recruited authors were frequently placed in the first and second positions of the authorship list. For the publication of scientific review papers, documents were found describing Merck marketing employees developing plans for manuscripts, contracting with medical publishing companies to ghostwrite manuscripts, and recruiting external, academically affiliated investigators to be authors. Recruited authors were commonly the sole author on the manuscript and offered honoraria for their participation. Among 96 relevant published articles, we found that 92% (22 of 24) of clinical trial articles published a disclosure of Merck's financial support, but only 50% (36 of 72) of review articles published either a disclosure of Merck sponsorship or a disclosure of whether the author had received any financial compensation from the company. This case-study review of industry documents demonstrates that clinical trial manuscripts related to rofecoxib were authored by sponsor employees but often attributed first authorship to academically affiliated investigators who did not always disclose industry financial support. Review manuscripts were often prepared by unacknowledged authors and subsequently attributed authorship to academically affiliated investigators who often did not disclose industry financial support.

14 CFR 13.211 - Service of documents.

Code of Federal Regulations, 2012 CFR

2012-01-01

... mail. (g) Valid service. A document that was properly addressed, was sent in accordance with this... party at the time of filing. Service on a party's attorney of record or a party's designated... consist of a statement, dated and signed by the person filing the document, that the document was...

14 CFR 13.211 - Service of documents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... mail. (g) Valid service. A document that was properly addressed, was sent in accordance with this... party at the time of filing. Service on a party's attorney of record or a party's designated... consist of a statement, dated and signed by the person filing the document, that the document was...

14 CFR 13.211 - Service of documents.

Code of Federal Regulations, 2011 CFR

2011-01-01

... mail. (g) Valid service. A document that was properly addressed, was sent in accordance with this... party at the time of filing. Service on a party's attorney of record or a party's designated... consist of a statement, dated and signed by the person filing the document, that the document was...

14 CFR 13.211 - Service of documents.

Code of Federal Regulations, 2013 CFR

2013-01-01

... mail. (g) Valid service. A document that was properly addressed, was sent in accordance with this... party at the time of filing. Service on a party's attorney of record or a party's designated... consist of a statement, dated and signed by the person filing the document, that the document was...

Market Analysis and Consumer Impacts Source Document. Part II. Review of Motor Vehicle Market and Consumer Expenditures on Motor Vehicle Transportation

DOT National Transportation Integrated Search

1980-12-01

This source document on motor vehicle market analysis and consumer impacts consists of three parts. Part II consists of studies and review on: motor vehicle sales trends; motor vehicle fleet life and fleet composition; car buying patterns of the busi...

Quality Document Examples (Record of Decision of the Year Contest)

EPA Pesticide Factsheets

This page provides document examples with clear documentation that are consistent with the Superfund Program's policy and regulations. The examples provided here are the winners of the Superfund ROD of the Year Contest (1999-2004)

77 FR 41332 - Fisheries of the Exclusive Economic Zone Off Alaska; Arrowtooth Flounder, Flathead Sole, Rex Sole...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

...NMFS is prohibiting directed fishing for arrowtooth flounder, flathead sole, rex sole, deep-water flatfish, and shallow-water flatfish in the Western Regulatory Area of the Gulf of Alaska (GOA). This action is necessary to limit incidental catch of Pacific ocean perch by vessels fishing for arrowtooth flounder, flathead sole, rex sole, deep-water flatfish, and shallow-water flatfish in the Western Regulatory Area of the GOA.

NASA software documentation standard software engineering program

NASA Technical Reports Server (NTRS)

1991-01-01

The NASA Software Documentation Standard (hereinafter referred to as Standard) can be applied to the documentation of all NASA software. This Standard is limited to documentation format and content requirements. It does not mandate specific management, engineering, or assurance standards or techniques. This Standard defines the format and content of documentation for software acquisition, development, and sustaining engineering. Format requirements address where information shall be recorded and content requirements address what information shall be recorded. This Standard provides a framework to allow consistency of documentation across NASA and visibility into the completeness of project documentation. This basic framework consists of four major sections (or volumes). The Management Plan contains all planning and business aspects of a software project, including engineering and assurance planning. The Product Specification contains all technical engineering information, including software requirements and design. The Assurance and Test Procedures contains all technical assurance information, including Test, Quality Assurance (QA), and Verification and Validation (V&V). The Management, Engineering, and Assurance Reports is the library and/or listing of all project reports.

77 FR 26304 - Federal Housing Administration (FHA) Healthcare Facility Documents: Proposed Revisions and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-03

...Consistent with the Paperwork Reduction Act of 1995 (PRA), HUD is publishing for public comment a comprehensive set of closing and other documents used in connection with transactions involving healthcare facilities (excluding hospitals) that are insured pursuant to section 232 of the National Housing Act (Section 232). In addition to meeting PRA requirements, this notice seeks public comment for the purpose of enlisting input from the lending industry and other interested parties in the development, updating, and adoption of a set of instruments (collectively, healthcare facility documents) that offer the requisite protection to all parties in these FHA-insured mortgage transactions, consistent with modern real estate and mortgage lending laws and practices. The healthcare facility documents, which are the subject of this notice, can be viewed on HUD's Web site: www.hud.gov/232forms. HUD is also publishing today a proposed rule that will submit for public comment certain revisions to FHA's Section 232 regulations for the purpose of ensuring consistency between the program regulations and the revised healthcare facility documents.

Representing Information in Patient Reports Using Natural Language Processing and the Extensible Markup Language

PubMed Central

Friedman, Carol; Hripcsak, George; Shagina, Lyuda; Liu, Hongfang

1999-01-01

Objective: To design a document model that provides reliable and efficient access to clinical information in patient reports for a broad range of clinical applications, and to implement an automated method using natural language processing that maps textual reports to a form consistent with the model. Methods: A document model that encodes structured clinical information in patient reports while retaining the original contents was designed using the extensible markup language (XML), and a document type definition (DTD) was created. An existing natural language processor (NLP) was modified to generate output consistent with the model. Two hundred reports were processed using the modified NLP system, and the XML output that was generated was validated using an XML validating parser. Results: The modified NLP system successfully processed all 200 reports. The output of one report was invalid, and 199 reports were valid XML forms consistent with the DTD. Conclusions: Natural language processing can be used to automatically create an enriched document that contains a structured component whose elements are linked to portions of the original textual report. This integrated document model provides a representation where documents containing specific information can be accurately and efficiently retrieved by querying the structured components. If manual review of the documents is desired, the salient information in the original reports can also be identified and highlighted. Using an XML model of tagging provides an additional benefit in that software tools that manipulate XML documents are readily available. PMID:9925230

[Treatment of chronic shoulder tendinitis].

PubMed

Brox, J I; Bøhmer, A S; Ljunggren, A E; Staff, P H

1994-02-20

The authors review current treatment modalities and present a study comparing supervised exercises and arthroscopic surgery in patients with rotator cuff disease. Exercises supervised by a physiotherapist emphasize relearning of normal patterns of movement and local endurance training to improve tendon and muscle tissue, and are supplemented by ergonomic advice. The clinician should try to elucidate whether the patient is supposed to benefit solely from information and self-treatment. For several of the currently used treatment modalities, such as ultrasound, soft laser, heat and massage, no effect has been documented. Surgery should be reserved for persons who do not benefit from supervised exercises. Careful rehabilitation is necessary for patients who report having a physically demanding job.

Renal clearance studies of effect of left atrial distension in the dog.

NASA Technical Reports Server (NTRS)

Kinney, M. J.; Discala, V. A.

1972-01-01

Investigation of the water diuresis of left atrial distension in 16 dogs on the basis of clearance studies employing hydration, chronic and acute salt loading, deoxycorticosterone (DOCA) in excess, and distal tubular nephron blockade with diuretics. The diuresis was found in hydrated and salt-loaded dogs and was independent of DOCA and presumed renin depletion. It was not found in five dogs after distal tubular blockade. No significant reproducible saluresis was ever documented. The water diuresis was always stopped by exogenous vasopressin (seven dogs). Antidiuretic hormone inhibition with distal tubular nephron water permeability changes appears to be the sole mechanism of the diuresis of left atrial distension in the dog.

Correlation of Shear Strength Between Longitudial and Transverse Specimens

DTIC Science & Technology

2012-05-17

Transverse Specimens" (2012). University of New Orleans Theses and Dissertations. Paper 1435. http://scholarworks.uno.edu/ td /1435 Report Documentation... ATI ) and they were  the sole providers of this metal during this project.  ATI  called the alloy:  ATI  425; it is very similar  in its properties to...Nie, C.; Dong, P.. Traction Stress Based Shear Strength Definition of Fillet Welds. Pending  Publishing.  [5] ATI  38‐644 Beta Titanium Alloy. Technical

Low-level laser therapy of tinnitus: A case for the dentist?

NASA Astrophysics Data System (ADS)

Tuner, Jan

2001-04-01

Tinnitus is a debilitating condition with an increasing incidence, especially among the young generation, due to intensive sound levels at concerts and in headsets. It is, however, not solely a problem of the modern world. The condition is described in papyrus documents dating back 600 BC. Some famous historic persons have suffered from tinnitus, such as Martin Luther, Jean-Jaques Rousseau and Ludwig van Beethoven. It is estimated that roughly one person in ten is affected by tinnitus of some degree. The origin of tinnitus is controversial. It is claimed that tinnitus is located in the inner ear but also that it actually is situated in the brain cortex, as evidenced by PET-scanning.

AIDS is an exception to bus system's offer of lower fares.

PubMed

1997-05-02

The American Civil Liberties Union (ACLU) sued the Metro Link bus system in Rock Island, IL on behalf of [name removed]. The suit claims that the bus system explicitly excludes people with AIDS from a reduced-rate fare program for riders with disabilities. Currently, Metro Link offers a discount to senior citizens or people with disabilities who have documentation. The application for the discount specifically rules out people whose sole disability is AIDS. [Name removed] asked Metro Link to eliminate the exclusion. When the request was refused, the ACLU sued, alleging a violation of the Americans with Disabilities Act (ADA), the Rehabilitation Act, and [name removed]'s constitutional right to equal protection under the law.

75 FR 31321 - Fisheries of the Exclusive Economic Zone Off Alaska; Rock Sole, Flathead Sole, and “Other...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-03

.... 0910131363-0087-02] RIN 0648-XW74 Fisheries of the Exclusive Economic Zone Off Alaska; Rock Sole, Flathead... participating in the Amendment 80 limited access fishery in the Bering Sea and Aleutian Islands management area... the trawl rock sole, flathead sole, and ``other flatfish'' fishery category by vessels participating...

Feeding Behaviour, Swimming Activity and Boldness Explain Variation in Feed Intake and Growth of Sole (Solea solea) Reared in Captivity

PubMed Central

Mas-Muñoz, Julia; Komen, Hans; Schneider, Oliver; Visch, Sander W.; Schrama, Johan W.

2011-01-01

The major economic constraint for culturing sole (Solea solea) is its slow and variable growth. The objective was to study the relationship between feed intake/efficiency, growth, and (non-) feeding behaviour of sole. Sixteen juveniles with an average (SD) growth of 2.7 (1.9) g/kg0.8/d were selected on their growth during a 4-week period in which they were housed communally with 84 other fish. Selected fish were housed individually during a second 4-week period to measure individual feed intake, growth, and behaviour. Fish were hand-fed three times a day during the dark phase of the day until apparent satiation. During six different days, behaviour was recorded twice daily during 3 minutes by direct observations. Total swimming activity, frequency of burying and of escapes were recorded. At the beginning and end of the growth period, two sequential behavioural tests were performed: “Novel Environment” and “Light Avoidance”. Fish housed individually still exhibited pronounced variation in feed intake (CV = 23%), growth (CV = 25%) and behavior (CV = 100%). Differences in feed intake account for 79% of the observed individual differences in growth of sole. Fish with higher variation in feed intake between days and between meals within days had significantly a lower total feed intake (r = −0.65 and r = −0.77) and growth. Active fish showed significantly higher feed intake (r = 0.66) and growth (r = 0.58). Boldness during both challenge tests was related to fast growth: (1) fish which reacted with a lower latency time to swim in a novel environment had significantly higher feed intake (r = −0.55) and growth (r = −0.66); (2) fish escaping during the light avoidance test tended to show higher feed intake (P<0.1) and had higher growth (P<0.05). In conclusion, feeding consistency, swimming activity in the tank, and boldness during behavioral tests are related to feed intake and growth of sole in captivity. PMID:21738651

Feeding behaviour, swimming activity and boldness explain variation in feed intake and growth of sole (Solea solea) reared in captivity.

PubMed

Mas-Muñoz, Julia; Komen, Hans; Schneider, Oliver; Visch, Sander W; Schrama, Johan W

2011-01-01

The major economic constraint for culturing sole (Solea solea) is its slow and variable growth. The objective was to study the relationship between feed intake/efficiency, growth, and (non-) feeding behaviour of sole. Sixteen juveniles with an average (SD) growth of 2.7 (1.9) g/kg(0.8)/d were selected on their growth during a 4-week period in which they were housed communally with 84 other fish. Selected fish were housed individually during a second 4-week period to measure individual feed intake, growth, and behaviour. Fish were hand-fed three times a day during the dark phase of the day until apparent satiation. During six different days, behaviour was recorded twice daily during 3 minutes by direct observations. Total swimming activity, frequency of burying and of escapes were recorded. At the beginning and end of the growth period, two sequential behavioural tests were performed: "Novel Environment" and "Light Avoidance". Fish housed individually still exhibited pronounced variation in feed intake (CV = 23%), growth (CV = 25%) and behavior (CV = 100%). Differences in feed intake account for 79% of the observed individual differences in growth of sole. Fish with higher variation in feed intake between days and between meals within days had significantly a lower total feed intake (r = -0.65 and r = -0.77) and growth. Active fish showed significantly higher feed intake (r = 0.66) and growth (r = 0.58). Boldness during both challenge tests was related to fast growth: (1) fish which reacted with a lower latency time to swim in a novel environment had significantly higher feed intake (r = -0.55) and growth (r = -0.66); (2) fish escaping during the light avoidance test tended to show higher feed intake (P<0.1) and had higher growth (P<0.05). In conclusion, feeding consistency, swimming activity in the tank, and boldness during behavioral tests are related to feed intake and growth of sole in captivity.

A case report of lameness in two dairy goat herds; a suspected combination of nutritional factors concurrent with treponeme infection.

PubMed

Groenevelt, Margit; Anzuino, Katharine; Smith, Sue; Lee, Michael R F; Grogono-Thomas, Rosemary

2015-12-16

Two dairy goat farms with high level of lameness in lactating animals were presented for further investigation. Farm 1 and Farm 2 presented with 37 and 67% morbidity, respectively. Both farms had an all year round indoor system, feeding ad libitum concentrate with forage available at all times. The lameness was found to be based in the foot. Previous treatments consisting of biweekly footbathing with zinc sulphate, spraying lesions with oxytetracycline spray and packing lesions with copper crystals on a single occasion and single injections with long acting oxytetracycline had not been successful. Mild cases had signs of haemorrhaging in the white line or on the sole of the foot. Moderate cases showed under running of the wall horn or small areas of exposed sole corium. Severe cases would consist of horn or wall separation with the corium exposed and infected. In extreme cases only the wall horn of the claw remained, with a large area of necrotic tissue in the centre and no healthy corium visible. Only one animal was seen to have interdigital lesions. Polymerase chain reaction (PCR) and culture of swabs taken from exposed corium and the interdigital space were negative for Dichelobacter nodosus but PCR for treponemes were positive in both the adults and the youngstock tested. Due to the high level of concentrate in the diet of these goats, nutrition was thought to contribute to the problem. Transcutaneous rumen fluid samples were taken and pH was measured on both farms, with 35% of the samples below pH value 5.5. No definite diagnosis could be made. However, the results suggest both treponemes and nutrition play a role in the aetiology of the lameness. The initial sole or wall horn lesions were thought to be secondarily infected by treponemes. Further investigation is needed to definitively diagnose the cause and contributing factors for this lameness.

Antibiotic treatment as sole management of Helicobacter pylori-negative gastric MALT lymphoma: a single center experience with prolonged follow-up.

PubMed

Raderer, Markus; Wöhrer, Stefan; Kiesewetter, Barbara; Dolak, Werner; Lagler, Heimo; Wotherspoon, Andrew; Muellauer, Leonhard; Chott, Andreas

2015-06-01

Relatively little is known about the long-term outcome of patients with Helicobacter pylori (HP)-negative gastric lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with antibiotic therapy as sole management. We have analyzed all patients with HP-negative gastric MALT lymphoma undergoing antibiotic therapy as sole management of their disease. HP negativity was defined as negative histology, breath test and serology, and response to treatment, survival and long-term outcome was assessed together with clinico-pathological characteristics including t(11; 18) (q21; q21) translocation. Out of 97 patients with gastric MALT lymphoma, 24 were HP-negative, and 13 (5 females and 8 males) underwent only antibiotic management for initial therapy. Eight had stage I and five were found to have stage II disease, with three patients suffering from an underlying autoimmune disease. Antibiotic therapy consisted of standard HP eradication regimens consisting of clarithromycin in all patients, along with metronidazole in seven and amoxicillin in six plus a proton-pump inhibitor. After a median follow-up of 95 months (42-, 181+), 12/13 patients are alive. Six patients with stage I disease achieved an objective response (five complete (CR) and one partial remission, 46 %), four had stable disease (lasting 11-27 months), and three progressed. All patients with stable disease received chemotherapy, but only one patient due to clear cut progression. One patient relapsed 23 months after initial CR, and achieved a second CR with antibiotics now lasting 87 months. These results indicate that a relevant percentage of patients with HP-negative gastric MALT lymphoma may benefit from antibiotic therapy and do not require additional oncological therapies. Our data suggest that the remissions seen in these patients might be durable as evidenced by prolonged follow-up in our series.

Program Helps Standardize Documentation Of Software

NASA Technical Reports Server (NTRS)

Howe, G.

1994-01-01

Intelligent Documentation Management System, IDMS, computer program developed to assist project managers in implementing information system documentation standard known as NASA-STD-2100-91, NASA STD, COS-10300, of NASA's Software Management and Assurance Program. Standard consists of data-item descriptions or templates, each of which governs particular component of software documentation. IDMS helps program manager in tailoring documentation standard to project. Written in C language.

Effect of rocker-soled shoes on parameters of knee joint load in knee osteoarthritis.

PubMed

Madden, Elizabeth G; Kean, Crystal O; Wrigley, Tim V; Bennell, Kim L; Hinman, Rana S

2015-01-01

This study evaluated the immediate effects of rocker-soled shoes on parameters of the knee adduction moment (KAM) and pain in individuals with knee osteoarthritis (OA). Three-dimensional gait analysis was performed on 30 individuals (mean (SD): age, 61 (7) yr; 15 (50%) male) with radiographic and symptomatic knee OA under three walking conditions in a randomized order: i) wearing rocker-soled shoes (Skechers Shape-ups), ii) wearing non-rocker-soled shoes (ASICS walking shoes), and iii) barefoot. Peak KAM and KAM angular impulse were measured as primary indicators of knee load distribution. Secondary measures included the knee flexion moment (KFM) and knee pain during walking. Peak KAM was significantly lower when wearing the rocker-soled shoes compared with that when wearing the non-rocker-soled shoes (mean difference (95% confidence interval), -0.27 (-0.42 to -0.12) N·m/BW × Ht%; P < 0.001). Post hoc tests revealed no significant difference in KAM impulse between rocker-soled and non-rocker-soled shoe conditions (P = 0.13). Both peak KAM and KAM impulse were significantly higher during both shoe conditions compared with those during the barefoot condition (P < 0.001). There were no significant differences in KFM (P = 0.36) or knee pain (P = 0.89) between conditions. Rocker-soled shoes significantly reduced peak KAM when compared with non-rocker-soled shoes, without a concomitant change in KFM, and thus may potentially reduce medial knee joint loading. However, KAM parameters in the rocker-soled shoes remained significantly higher than those during barefoot walking. Wearing rocker-soled shoes did not have a significant immediate effect on walking pain. Further research is required to evaluate whether rocker-soled shoes can influence symptoms and progression of knee OA with prolonged wear.

Now You See It: Using Documentation to Make Learning Visible in LCs

ERIC Educational Resources Information Center

Mino, Jack J.

2014-01-01

The practice of documentation is discussed as a means of making learning visible in the LC classroom. A documentation heuristic consisting of a four-stage cycle was used to capture, analyze and report what Bass and Eynon (2009) refer to as the "visible evidence of invisible learning" (p. 5). A variety of documentation samples are…

An Inventory of Documents on Educational Planning and Management in Asia and the Pacific.

ERIC Educational Resources Information Center

Mellor, Warren L., Ed.

This document comprises a UNESCO-sponsored inventory of documents on educational planning and management in Asia and the Pacific. The database consists of 714 documents from participating countries, divided into 10 subsections by country and indexed according to author and subject. The main entries are grouped alphabetically by country, as…

Evaluation and Assessment in Mathematics Education. Science and Technology Education Document Series No. 32.

ERIC Educational Resources Information Center

Robitaille, David F.

This document contains 15 papers selected from 47 papers presented at a theme group of the Sixth International Congress on Mathematical Education. The papers included have been divided into four groups. The first group consists of a survey paper, which discusses the history of assessment and evaluation. The second section consists of six papers…

On the Creation of Hypertext Links in Full-Text Documents: Measurement of Inter-Linker Consistency.

ERIC Educational Resources Information Center

Ellis, David; And Others

1994-01-01

Describes a study in which several different sets of hypertext links are inserted by different people in full-text documents. The degree of similarity between the sets is measured using coefficients and topological indices. As in comparable studies of inter-indexer consistency, the sets of links used by different people showed little similarity.…

A discursive analysis concerning information on "ADHD" presented to parents by the National Institute of Mental Health (USA).

PubMed

Erlandsson, Soly; Lundin, Linda; Punzi, Elisabeth

2016-01-01

A discourse analysis was performed based on an online document under the headline: "What is Attention Deficit Hyperactivity Disorder (ADHD, ADD)?" published by the National Institute of Mental Health (NIMH), USA. Three parts of the document were analysed: (1) The introductory part, as this sets the tone of the whole text. (2) Parts of the text that were specifically addressed to parents. (3) Etiology and pathology of "ADHD" with reference to a number of different symptoms and behaviors. Inattention and hyperactivity are presented in the document as a floating spectrum of symptoms caused by "ADHD." Other factors of importance for children's development, that is, early attachment, close relationships, previous experiences, culture, and contexts are ignored. Children who are perceived as inattentive and hyperactive are portrayed as having inherent difficulties with no reference to their emotions or efforts to communicate. The child is viewed as suffering from a lifelong disorder that might not be cured but controlled by a diagnosis and subsequent medication. Parents are advised to control their child's behavior and to strive for early diagnosis in order to receive treatment provided by experts. Those who are presented as experts rely on a biomedical model, and in the document, detailed descriptions of medication to correct the undesired behaviors are provided. The value of judgment in the assessment of different symptoms and behaviors that signifies "ADHD" is absent, rather taken-for-granted beliefs were identified throughout the document. A heterogeneous set of behaviors is solely described as a disorder and hereafter it is stressed that the same behaviors are caused by the disorder. In this manner, cause and effects of "ADHD" are intertwined through circular argumentation.

Preclinical assessment of abuse liability of biologics: In defense of current regulatory control policies.

PubMed

Gauvin, David V; Zimmermann, Zachary J; Baird, Theodore J

2015-10-01

Current regulatory policies of both the US Food and Drug Administration and Drug Enforcement Administration do not delineate automatic exceptions for biologics with respect to preclinical assessments for abuse liability of all new entities. As defined in current guidance documents and drug control policies, an exception may be given upon thorough review of available data, therapeutic target and in consultation with the Controlled Substances Staff within the Center for Drug Evaluation and Research of the FDA, but a blanket exception for all biological entities is not currently available. We review the abuse liability testing of four known biologics with definitive positive abuse liability signals in the three core abuse liability assays, self-administration, drug discrimination, and dependence potential described in the FDA draft guidance document. Interestingly, while all four examplars have positive abuse liability signals in all three assays, two of these biologics are controlled under the Comprehensive Drug Abuse and Control Act (CSA, 1970) and the other two are not currently controlled. Admittedly, these four biologics are small molecule entities. However, there is no reference to "molecular size" in the legally-binding statutory definition of biologics under the FD&C act or in the Controlled Substances Act. Neither of these drug control policy mandates have a bifurcated control status in which to make exceptions based solely on molecular size. With the current pharmaceutical focus on new technologies, such as "Trojan Horses", targeting the active transport of large molecule entities directly into the CNS, an argument to automatically exempt new molecular entities solely on molecular size is untenable. We argue that for the safety and health of general public the current regulatory control status be maintained until definitive criteria for exceptions can be identified and amended to both the FD&CA and CSA, if warranted. Copyright © 2015 Elsevier Inc. All rights reserved.

Consistency of psychotropic drug-drug interactions listed in drug monographs.

PubMed

Liu, Xinyue; Hatton, Randy C; Zhu, Yanmin; Hincapie-Castillo, Juan M; Bussing, Regina; Barnicoat, Marie; Winterstein, Almut G

With an increasing prevalence of psychotropic polypharmacy, clinicians depend on drug-drug interaction (DDI) references to ensure safe regimens, but the consistency of such information is frequently questioned. To evaluate the consistency of psychotropic DDIs documented in Clinical Pharmacology (CP), Micromedex (MM), and Lexicomp (LC) and summarize consistent psychotropic DDIs. In May 2016, we extracted severe or major psychotropic DDIs for 102 psychotropic drugs, including central nervous system (CNS) stimulants, antidepressants, an antimanic agent (lithium), antipsychotics, anticonvulsants, and anxiolytics-sedatives-hypnotics from CP, MM, and LC. We then summarized the psychotropic DDIs that were included in all 3 references and with evidence quality of "excellent" or "good" based on MM. We identified 1496, 938, and 1006 unique severe or major psychotropic DDIs from CP, MM, and LC, respectively. Common adverse effects related to psychotropic DDIs include increased or decreased effectiveness, CNS depression, neurotoxicity, QT prolongation, serotonin syndrome, and multiple adverse effects. Among these interactions, only 371 psychotropic DDIs were documented in all 3 references, 59 of which had "excellent" or "good" quality of evidence based on MM. The consistency of psychotropic DDI documentation across CP, MM, and LC is poor. DDI documentations need standards that would encourage consistency among drug information references. The list of the 59 DDIs may be useful in the assessment of psychotropic polypharmacy and highlighting DDI alerts in clinical practice. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Age compositions of flatfish stocks as determined by a new otolithometric method, its application in the estimation of growth, spawning potential and fisheries management

NASA Astrophysics Data System (ADS)

Katayama, Satoshi; Yamamoto, Masayuki; Gorie, Shigeaki

2010-11-01

We developed an ageing methodology and examined age composition of three flatfish stocks inhabiting the Seto Inland Sea, Japan. Ages were difficult to determine for three-lined tongue sole ( Cynoglossus abbreviates) and ridged-eye flounder ( Pleuronichthys cornutus) because the first year annulus ring was often indistinct; therefore, we used directional change in otolith growth to distinguish it. Sectioning and etching methods were powerful tools for identifying annual checks for red tongue sole ( Cynoglossus joyneri). Using these ageing methods, we determined age-length relationships and growth curves. The age composition of the populations studied and of the landings showed that a large proportion of the latter consisted of individuals under the mean age of sexual maturity, thereby reducing the percent spawning potential ratio (%SPR) to ≈ 20% for all species. These findings suggest that fishing pressure on immature fish is leading to overfishing of these flatfish stocks.

Modeled connectivity between northern rock sole (Lepidopsetta polyxystra) spawning and nursery areas in the eastern Bering Sea

NASA Astrophysics Data System (ADS)

Cooper, D. W.; Duffy-Anderson, J. T.; Stockhausen, W. T.; Cheng, W.

2013-11-01

Connectivity between spawning and potential nursery areas of northern rock sole, Lepidopsetta polyxystra, in the eastern Bering Sea was examined using an individual-based biophysical-coupled model. Presumed spawning areas were identified using historical field-collected ichthyoplankton data, and nursery habitats were characterized based on previously described settlement areas. Simulated larvae were released from spawning areas near the Pribilof Islands, south of the Pribilof Islands along the outer continental shelf, on the north side of the Alaska Peninsula, and in the Gulf of Alaska south of Unimak Island. Simulated larvae were transported along two general pathways: 1) northwards along the outer continental shelf from Unimak Island towards the Pribilof Islands and further north offshore of mainland Alaska, and 2) eastward along the Alaska Peninsula. At the end of the 2-month simulation, drift pathways placed pre-settlement stage larvae offshore of known nursery areas of older juveniles near mainland Alaska, consistent with a hypothesis that initial settlement may be followed by substantial post-settlement redistribution.

Semantic Clinical Guideline Documents

PubMed Central

Eriksson, Henrik; Tu, Samson W.; Musen, Mark

2005-01-01

Decision-support systems based on clinical practice guidelines can support physicians and other health-care personnel in the process of following best practice consistently. A knowledge-based approach to represent guidelines makes it possible to encode computer-interpretable guidelines in a formal manner, perform consistency checks, and use the guidelines directly in decision-support systems. Decision-support authors and guideline users require guidelines in human-readable formats in addition to computer-interpretable ones (e.g., for guideline review and quality assurance). We propose a new document-oriented information architecture that combines knowledge-representation models with electronic and paper documents. The approach integrates decision-support modes with standard document formats to create a combined clinical-guideline model that supports on-line viewing, printing, and decision support. PMID:16779037

Documenting Student Competence through Effective Performance Assessment: Employability Skills. Workshop Summary.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. Agricultural Curriculum Materials Service.

This report contains 26 performance assessments for documenting student employability skills. Each performance assessment consists of the following: a competency; a terminal performance objective (outcome); competency builders and pupil performance objectives (criteria for documenting mastery of the objective); applied academic competencies;…

Recommendations for and Documentation of Biological Values for Use in Risk Assessment

EPA Science Inventory

The document was prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response. The document consists of an extensive compliation of values gleaned from published li...

A Method of Retrospective Computerized System Validation for Drug Manufacturing Software Considering Modifications

NASA Astrophysics Data System (ADS)

Takahashi, Masakazu; Fukue, Yoshinori

This paper proposes a Retrospective Computerized System Validation (RCSV) method for Drug Manufacturing Software (DMSW) that relates to drug production considering software modification. Because DMSW that is used for quality management and facility control affects big impact to quality of drugs, regulatory agency required proofs of adequacy for DMSW's functions and performance based on developed documents and test results. Especially, the work that explains adequacy for previously developed DMSW based on existing documents and operational records is called RCSV. When modifying RCSV conducted DMSW, it was difficult to secure consistency between developed documents and test results for modified DMSW parts and existing documents and operational records for non-modified DMSW parts. This made conducting RCSV difficult. In this paper, we proposed (a) definition of documents architecture, (b) definition of descriptive items and levels in the documents, (c) management of design information using database, (d) exhaustive testing, and (e) integrated RCSV procedure. As a result, we could conduct adequate RCSV securing consistency.

Dramatic declines in neotropical salamander populations are an important part of the global amphibian crisis

PubMed Central

Rovito, Sean M.; Parra-Olea, Gabriela; Vásquez-Almazán, Carlos R.; Papenfuss, Theodore J.; Wake, David B.

2009-01-01

We document major declines of many species of salamanders at several sites in Central America and Mexico, with emphasis on the San Marcos region of Guatemala, one of the best studied and most diverse salamander communities in the Neotropics. Profound declines of several formerly abundant species, including 2 apparent extinctions, are revealed. Terrestrial microhabitat specialists at mid- to high elevations have declined more than microhabitat generalists. These terrestrial microhabitat specialists have largely disappeared from multiple sites in western Guatemala, including in well-protected areas, suggesting that the phenomenon cannot be explained solely by localized habitat destruction. Major declines in southern Mexican plethodontid salamanders occurred in the late 1970s to early 1980s, concurrent with or preceding many reported frog declines. The species in decline comprise several major evolutionary lineages of tropical salamanders, underscoring that significant portions of the phylogenetic diversity of Neotropical salamanders are at risk. Our results highlight the urgent need to document and understand Neotropical salamander declines as part of the larger effort to conserve global amphibian diversity. PMID:19204286

Depth and substrate as determinants of distribution of juvenile flathead sole (Hippoglossoides elassodon) and rock sole (Pleuronectes bilineatus), in Kachemak Bay, Alaska

USGS Publications Warehouse

Abookire, Alisa A.; Norcross, Brenda L.

1998-01-01

Three transects in Kachemak Bay, Alaska, were sampled in September 1994, May and August 1995, and February, May, and August 1996. Juvenile flathead sole, Hippoglossoides elassodon, and rock sole, Pleuronectes bilineatus, were the most abundant flatfishes, comprising 65-85% of all fiatfishes captured at any period. Collections of fish and sediments were made at regular depth contour intervals of l0 m. Habitat distribution was described by depth at 10 m increments and sediment percent weights of gravel, sand, and mud. Year-round habitat of flathead sole age-0 was primarily from 40 to 60 m, and age-1 habitat was primarily from 40 to 80 m. Summer habitat of rock sole age-0 and -1 was from 10 to 30 m, and in winter they moved offshore to depths of up to 150 m. Both age classes of flathead sole were most abundant on mixed mud sediments, while age-1 were also in high abundance on muddy sand sediments. Rock sole age-0 and -1 were most abundant on sand, though age-1 were also found on a variety of sediments both finer and coarser grained than sand. Flathead sole and rock sole had distinctive depth and sediment habitats. When habitat overlap occurred between the species, it was most often due to rock sole moving offshore in the winter. Abundances were not significantly different among seasons for age-1 flatfishes.

Molecular basis of non-syndromic hypospadias: systematic mutation screening and genome-wide copy-number analysis of 62 patients.

PubMed

Kon, M; Suzuki, E; Dung, V C; Hasegawa, Y; Mitsui, T; Muroya, K; Ueoka, K; Igarashi, N; Nagasaki, K; Oto, Y; Hamajima, T; Yoshino, K; Igarashi, M; Kato-Fukui, Y; Nakabayashi, K; Hayashi, K; Hata, K; Matsubara, Y; Moriya, K; Ogata, T; Nonomura, K; Fukami, M

2015-03-01

What percentage of cases with non-syndromic hypospadias can be ascribed to mutations in known causative/candidate/susceptibility genes or submicroscopic copy-number variations (CNVs) in the genome? Monogenic and digenic mutations in known causative genes and cryptic CNVs account for >10% of cases with non-syndromic hypospadias. While known susceptibility polymorphisms appear to play a minor role in the development of this condition, further studies are required to validate this observation. Fifteen causative, three candidate, and 14 susceptible genes, and a few submicroscopic CNVs have been implicated in non-syndromic hypospadias. Systematic mutation screening and genome-wide copy-number analysis of 62 patients. The study group consisted of 57 Japanese and five Vietnamese patients with non-syndromic hypospadias. Systematic mutation screening was performed for 25 known causative/candidate/susceptibility genes using a next-generation sequencer. Functional consequences of nucleotide alterations were assessed by in silico assays. The frequencies of polymorphisms in the patient group were compared with those in the male general population. CNVs were analyzed by array-based comparative genomic hybridization and characterized by fluorescence in situ hybridization. Seven of 62 patients with anterior or posterior hypospadias carried putative pathogenic mutations, such as hemizygous mutations in AR, a heterozygous mutation in BNC2, and homozygous mutations in SRD5A2 and HSD3B2. Two of the seven patients had mutations in multiple genes. We did not find any rare polymorphisms that were abundant specifically in the patient group. One patient carried mosaic dicentric Y chromosome. The patient group consisted solely of Japanese and Vietnamese individuals and clinical and hormonal information of the patients remained rather fragmentary. In addition, mutation analysis focused on protein-altering substitutions. Our data provide evidence that pathogenic mutations can underlie both mild and severe hypospadias and that HSD3B2 mutations cause non-syndromic hypospadias as a sole clinical manifestation. Most importantly, this is the first report documenting possible oligogenicity of non-syndromic hypospadias. This study was funded by the Grant-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology; by the Grant-in-Aid from the Japan Society for the Promotion of Science; by the Grants from the Ministry of Health, Labour and Welfare, from the National Center for Child Health and Development and from the Takeda Foundation. The authors have no competing interests to disclose. Not applicable. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

40 CFR 300.700 - Activities by other persons.

Code of Federal Regulations, 2010 CFR

2010-07-01

... action is conducted in accordance with the preauthorization decision document, and costs are reasonable... preauthorization decision document. (8) For a claim to be awarded under section 111 of CERCLA, EPA must certify that the costs were necessary and consistent with the preauthorization decision document. (e) Section...

Metamorphic sole formation reveals plate interface rheology during early subduction

NASA Astrophysics Data System (ADS)

Mathieu, S.; Agard, P.; Dubacq, B.; Plunder, A.; Prigent, C.

2015-12-01

Metamorphic soles are m to ~500m thick tectonic slices welded beneath most large ophiolites. They correspond to highly to mildly deformed portions of oceanic lithosphere metamorphosed at amphibolite to granulite facies peak conditions. Metamorphic soles are interpreted as formed ≤1-2Ma after intraoceanic subduction initiation by heat transfer from the hot, incipient mantle wegde to the underthrusting lower plate. Their early accretion and exhumation together with the future ophiolite implies at least one jump of the subduction plate interface from above to below the metamorphic sole. Metamorphic soles thus represent one of the few remnants of the very early evolution of the subduction plate interface and provide major constraints on the thermal structure and the effective rheology of the crust and mantle along the nascent slab interface.We herein present a structural and petrological detailed description of the Oman and Turkey metamorphic soles. Both soles present a steep inverted metamorphic structure, with isograds subparallel to the peridotite contact, in which the proportion of mafic rocks, pressure and temperature conditions increase upward. They comprise, as most metamorphic soles worldwide, two main units: (1) a high-grade unit adjacent to the overlying peridotite composed of granulitized to amphibolized metabasalts, with rare metasedimentary interlayers (~800±100ºC at 10±2kbar) and (2) a low-grade greenschist facies unit composed of metasedimentary rocks with rare metatuffs (~500±100ºC at 5±2kbar). We provide for the first time refined P-T peak condition estimations by means of pseudosection modelling and maximum temperature constraints for the Oman low-grade sole by RAMAN thermometry. In order to quantify micro-scale deformations trough the sole, we also present EBSD data on the Oman garnet-bearing and garnet-free high-grade sole.With these new constraints, we finally propose a new conceptual mechanical model for metamorphic sole formation. This model excludes the presence of a continuous inverted metamorphic gradient through the sole but implies the stacking of several homogeneous slivers to constitute the present structure of the sole. These successive thrusts are the result of rheological changes as the plate interface progressively cools.

NASA Software Documentation Standard

NASA Technical Reports Server (NTRS)

1991-01-01

The NASA Software Documentation Standard (hereinafter referred to as "Standard") is designed to support the documentation of all software developed for NASA; its goal is to provide a framework and model for recording the essential information needed throughout the development life cycle and maintenance of a software system. The NASA Software Documentation Standard can be applied to the documentation of all NASA software. The Standard is limited to documentation format and content requirements. It does not mandate specific management, engineering, or assurance standards or techniques. This Standard defines the format and content of documentation for software acquisition, development, and sustaining engineering. Format requirements address where information shall be recorded and content requirements address what information shall be recorded. This Standard provides a framework to allow consistency of documentation across NASA and visibility into the completeness of project documentation. The basic framework consists of four major sections (or volumes). The Management Plan contains all planning and business aspects of a software project, including engineering and assurance planning. The Product Specification contains all technical engineering information, including software requirements and design. The Assurance and Test Procedures contains all technical assurance information, including Test, Quality Assurance (QA), and Verification and Validation (V&V). The Management, Engineering, and Assurance Reports is the library and/or listing of all project reports.

Quantitative evaluation of the relationship between dorsal wall length, sole thickness, and rotation of the distal phalanx in the bovine claw using computed tomography.

PubMed

Tsuka, T; Murahata, Y; Azuma, K; Osaki, T; Ito, N; Okamoto, Y; Imagawa, T

2014-10-01

Computed tomography (CT) was performed on 800 untrimmed claws (400 inner claws and 400 outer claws) of 200 pairs of bovine hindlimbs to investigate the relationships between dorsal wall length and sole thickness, and between dorsal wall length and the relative rotation angle of distal phalanx-to-sole surface (S-D angle). Sole thickness was 3.8 and 4.0 mm at the apex of the inner claws and outer claws, respectively, with dorsal wall lengths <70 mm. These sole thickness values were less than the critical limit of 5 mm, which is associated with a softer surface following thinning of the soles. A sole thickness of 5 mm at the apex was estimated to correlate with dorsal wall lengths of 72.1 and 72.7 mm for the inner and outer claws, respectively. Sole thickness was 6.1 and 6.4 mm at the apex of the inner and outer claws, respectively, with dorsal wall lengths of 75 mm. These sole thickness values were less than the recommended sole thickness of 7 mm based on the protective function of the soles. A sole thickness >7 mm at the apex was estimated to correlate with a dorsal wall length of 79.8 and 78.4mm for the inner and outer claws, respectively. The S-D angles were recorded as anteversions of 2.9° and 4.7° for the inner and outer claws, respectively, with a dorsal wall length of 75 mm. These values indicate that the distal phalanx is likely to have rotated naturally forward toward the sole surface. The distal phalanx rotated backward to the sole surface at 3.2° and 7.6° for inner claws with dorsal wall lengths of 90-99 and ≥100 mm, respectively; and at 3.5° for outer claws with a dorsal wall length ≥100 mm. Dorsal wall lengths of 85.7 and 97.2 mm were estimated to correlate with a parallel positional relationship of the distal phalanx to the sole surface in the inner and outer claws, respectively. Copyright © 2014 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

77 FR 12930 - Federal Acquisition Regulation: Socioeconomic Program Parity

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

... on May 6, 2011, reinstating the Rule of Two. C. Sole Source Dollar Thresholds Vary Among the... all socioeconomic programs had the same sole source dollar threshold. Response: The sole source dollar... business socioeconomic contracting program to utilize. D. Sole Source Authority Under the SDVOSB Program...

SPEAKEASY HELP documents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fink, J.K.

1972-07-01

The HELP documents provide SPEAKEASY users with concise definitions of most of the words available in the current processors. In this report, the documents are given in a variety of formats to enable one to find specific information quickly. The bulk of this report consists of computer read-out of the HELP library via SPEAKEASY.

Study of parameters of the nearest neighbour shared algorithm on clustering documents

NASA Astrophysics Data System (ADS)

Mustika Rukmi, Alvida; Budi Utomo, Daryono; Imro’atus Sholikhah, Neni

2018-03-01

Document clustering is one way of automatically managing documents, extracting of document topics and fastly filtering information. Preprocess of clustering documents processed by textmining consists of: keyword extraction using Rapid Automatic Keyphrase Extraction (RAKE) and making the document as concept vector using Latent Semantic Analysis (LSA). Furthermore, the clustering process is done so that the documents with the similarity of the topic are in the same cluster, based on the preprocesing by textmining performed. Shared Nearest Neighbour (SNN) algorithm is a clustering method based on the number of "nearest neighbors" shared. The parameters in the SNN Algorithm consist of: k nearest neighbor documents, ɛ shared nearest neighbor documents and MinT minimum number of similar documents, which can form a cluster. Characteristics The SNN algorithm is based on shared ‘neighbor’ properties. Each cluster is formed by keywords that are shared by the documents. SNN algorithm allows a cluster can be built more than one keyword, if the value of the frequency of appearing keywords in document is also high. Determination of parameter values on SNN algorithm affects document clustering results. The higher parameter value k, will increase the number of neighbor documents from each document, cause similarity of neighboring documents are lower. The accuracy of each cluster is also low. The higher parameter value ε, caused each document catch only neighbor documents that have a high similarity to build a cluster. It also causes more unclassified documents (noise). The higher the MinT parameter value cause the number of clusters will decrease, since the number of similar documents can not form clusters if less than MinT. Parameter in the SNN Algorithm determine performance of clustering result and the amount of noise (unclustered documents ). The Silhouette coeffisient shows almost the same result in many experiments, above 0.9, which means that SNN algorithm works well with different parameter values.

A Methodological Review and Critique of the "Intergenerational Transmission of Violence" Literature.

PubMed

Haselschwerdt, Megan L; Savasuk-Luxton, Rachel; Hlavaty, Kathleen

2017-01-01

Exposure to interpersonal or interparental violence (EIPV) and child abuse and maltreatment (CAM) are associated with an increased risk of maladaptive outcomes, including later involvement in adulthood intimate partner violence (IPV; often referred to as the theory of intergenerational transmission of violence). Recent meta-analyses, however, have documented a weak effect size when examining this association. By focusing on young adulthood, a development stage in which identity development and romantic relationship formation are salient tasks, we can provide insight into the association between EIPV, CAM, and IPV. Guided by the methodological critiques from the IPV and EIPV literatures, the present study reviewed the methodology used in 16 studies (published between 2002 and 2016) that tested the theory of intergenerational transmission of violence. The review study focused on how EIPV, CAM, and young adult dating violence were measured and analyzed, with the initial goal of better understanding how methodological decision informed the study's findings. Ultimately, we determined that there was simply too much methodological variability and yet too little methodological complexity to truly inform a review and discussion of the results; therefore, our review solely focused on the study's methodological decisions. Based on our review, we suggest that both of these challenges, too much variability and too little complexity, hinder our ability to examine the theory of intergenerational transmission of violence. Future research must strike a balance between methodological consistency and complexity to better understand the intricate nuances of IPV experiences and inform practice.

Literature search strategies for conducting knowledge-building and theory-generating qualitative systematic reviews.

PubMed

Finfgeld-Connett, Deborah; Johnson, E Diane

2013-01-01

To report literature search strategies for the purpose of conducting knowledge-building and theory-generating qualitative systematic reviews. Qualitative systematic reviews lie on a continuum from knowledge-building and theory-generating to aggregating and summarizing. Different types of literature searches are needed to optimally support these dissimilar reviews. Articles published between 1989-Autumn 2011. These documents were identified using a hermeneutic approach and multiple literature search strategies. Redundancy is not the sole measure of validity when conducting knowledge-building and theory-generating systematic reviews. When conducting these types of reviews, literature searches should be consistent with the goal of fully explicating concepts and the interrelationships among them. To accomplish this objective, a 'berry picking' approach is recommended along with strategies for overcoming barriers to finding qualitative research reports. To enhance integrity of knowledge-building and theory-generating systematic reviews, reviewers are urged to make literature search processes as transparent as possible, despite their complexity. This includes fully explaining and rationalizing what databases were used and how they were searched. It also means describing how literature tracking was conducted and grey literature was searched. In the end, the decision to cease searching also needs to be fully explained and rationalized. Predetermined linear search strategies are unlikely to generate search results that are adequate for purposes of conducting knowledge-building and theory-generating qualitative systematic reviews. Instead, it is recommended that iterative search strategies take shape as reviews evolve. © 2012 Blackwell Publishing Ltd.

The comparative behaviour of two combat boots under impact.

PubMed

Newell, Nicolas; Masouros, Spyros D; Pullen, Andy D; Bull, Anthony M J

2012-04-01

Improvised explosive devices have become the characteristic weapon of conflicts in Iraq and Afghanistan. While little can be done to mitigate against the effects of blast in free-field explosions, scaled blast simulations have shown that the combat boot can attenuate the effects on the vehicle occupants of anti-vehicular mine blasts. Although the combat boot offers some protection to the lower limb, its behaviour at the energies seen in anti-vehicular mine blast has not been documented previously. The sole of eight same-size combat boots from two brands currently used by UK troops deployed to Iraq and Afghanistan were impacted at energies of up to 518 J, using a spring-assisted drop rig. The results showed that the Meindl Desert Fox combat boot consistently experienced a lower peak force at lower impact energies and a longer time-to-peak force at higher impact energies when compared with the Lowa Desert Fox combat boot. This reduction in the peak force and extended rise time, resulting in a lower energy transfer rate, is a potentially positive mitigating effect in terms of the trauma experienced by the lower limb. Currently, combat boots are tested under impact at the energies seen during heel strike in running. Through the identification of significantly different behaviours at high loading, this study has shown that there is rationale in adding the performance of combat boots under impact at energies above those set out in international standards to the list of criteria for the selection of a combat boot.

Sláintecare - A ten-year plan to achieve universal healthcare in Ireland.

PubMed

Burke, Sara; Barry, Sarah; Siersbaek, Rikke; Johnston, Bridget; Ní Fhallúin, Maebh; Thomas, Steve

2018-05-22

In May 2017, an Irish cross-party parliamentary committee published the 'Houses of the Oireachtas Committee on the Future of Healthcare "Sláintecare" report'. The report, known as 'Sláintecare', is unique and historic as it is the first time there has been a cross-party political consensus on major health reform in Ireland. Sláintecare sets out a high level policy roadmap to deliver whole system reform and universal healthcare, phased over a ten year period and costed. Sláintecare details reform proposals which, if delivered, will establish; a universal, single-tier health service where patients are treated solely on the basis of health need; the reorientation of the health system 'towards integrated primary and community care, consistent with the highest quality of patient safety in as short a time-frame as possible'. Sláintecare has five interrelated components: population health; entitlements and access to healthcare; integrated care; funding; and implementation. In this article, the authors use documents in the public domain (parliamentary reports, public hearings, submissions to the Committee, media coverage, the final report of the Committee, speeches by Committee members) to describe the policy process and the main contents of the proposed Sláintecare reforms. It is too soon tell if the political consensus in the policy formation can hold for its implementation. Copyright © 2018 The Author(s). Published by Elsevier B.V. All rights reserved.

Scleredema adultorum of Buschke presenting as periorbital edema: a diagnostic challenge.

PubMed

Ioannidou, Despina I; Krasagakis, Konstantin; Stefanidou, Maria P; Karampekios, Spyros; Panayiotidis, John; Tosca, Androniki D

2005-02-01

Scleredema adultorum is a rare sclerotic disorder characterized by diffuse swelling and nonpitting induration of the skin. Its occurrence has been documented in association with infections, diabetes mellitus, paraproteinemia, multiple myeloma, and monoclonal gammopathy. We report an unusual case of a 48-year-old man with an asymptomatic bilateral eyelid edema of sudden onset. During a period of 6 months, the condition slowly progressed to extensive nonpitting edematous swelling restricted to the periorbital sites. The presumptive diagnosis of scleredema adultorum was confirmed by the presence of typical histologic findings. This case is unique in that the periorbital swelling remained as the sole clinical manifestation of scleredema during the 5-year follow-up and was complicated with partial vision blockage.

Good Practices in Model‐Informed Drug Discovery and Development: Practice, Application, and Documentation

PubMed Central

Burghaus, R; Cosson, V; Cheung, SYA; Chenel, M; DellaPasqua, O; Frey, N; Hamrén, B; Harnisch, L; Ivanow, F; Kerbusch, T; Lippert, J; Milligan, PA; Rohou, S; Staab, A; Steimer, JL; Tornøe, C; Visser, SAG

2016-01-01

This document was developed to enable greater consistency in the practice, application, and documentation of Model‐Informed Drug Discovery and Development (MID3) across the pharmaceutical industry. A collection of “good practice” recommendations are assembled here in order to minimize the heterogeneity in both the quality and content of MID3 implementation and documentation. The three major objectives of this white paper are to: i) inform company decision makers how the strategic integration of MID3 can benefit R&D efficiency; ii) provide MID3 analysts with sufficient material to enhance the planning, rigor, and consistency of the application of MID3; and iii) provide regulatory authorities with substrate to develop MID3 related and/or MID3 enabled guidelines. PMID:27069774

Psychometric Evaluation of the D-Catch, an Instrument to Measure the Accuracy of Nursing Documentation.

PubMed

D'Agostino, Fabio; Barbaranelli, Claudio; Paans, Wolter; Belsito, Romina; Juarez Vela, Raul; Alvaro, Rosaria; Vellone, Ercole

2017-07-01

To evaluate the psychometric properties of the D-Catch instrument. A cross-sectional methodological study. Validity and reliability were estimated with confirmatory factor analysis (CFA) and internal consistency and inter-rater reliability, respectively. A sample of 250 nursing documentations was selected. CFA showed the adequacy of a 1-factor model (chronologically descriptive accuracy) with an outlier item (nursing diagnosis accuracy). Internal consistency and inter-rater reliability were adequate. The D-Catch is a valid and reliable instrument for measuring the accuracy of nursing documentation. Caution is needed when measuring diagnostic accuracy since only one item measures this dimension. The D-Catch can be used as an indicator of the accuracy of nursing documentation and the quality of nursing care. © 2015 NANDA International, Inc.

31 CFR 800.223 - Solely for the purpose of passive investment.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Solely for the purpose of passive..., ACQUISITIONS, AND TAKEOVERS BY FOREIGN PERSONS Definitions § 800.223 Solely for the purpose of passive investment. Ownership interests are held or acquired solely for the purpose of passive investment if the...

Thermal Preference of Juvenile Dover Sole (Solea solea) in Relation to Thermal Acclimation and Optimal Growth Temperature

PubMed Central

Schram, Edward; Bierman, Stijn; Teal, Lorna R.; Haenen, Olga; van de Vis, Hans; Rijnsdorp, Adriaan D.

2013-01-01

Dover sole (Solea solea) is an obligate ectotherm with a natural thermal habitat ranging from approximately 5 to 27°C. Thermal optima for growth lie in the range of 20 to 25°C. More precise information on thermal optima for growth is needed for cost-effective Dover sole aquaculture. The main objective of this study was to determine the optimal growth temperature of juvenile Dover sole (Solea solea) and in addition to test the hypothesis that the final preferendum equals the optimal growth temperature. Temperature preference was measured in a circular preference chamber for Dover sole acclimated to 18, 22 and 28°C. Optimal growth temperature was measured by rearing Dover sole at 19, 22, 25 and 28°C. The optimal growth temperature resulting from this growth experiment was 22.7°C for Dover sole with a size between 30 to 50 g. The temperature preferred by juvenile Dover sole increases with acclimation temperature and exceeds the optimal temperature for growth. A final preferendum could not be detected. Although a confounding effect of behavioural fever on temperature preference could not be entirely excluded, thermal preference and thermal optima for physiological processes seem to be unrelated in Dover sole. PMID:23613837

Thermal preference of juvenile Dover sole (Solea solea) in relation to thermal acclimation and optimal growth temperature.

PubMed

Schram, Edward; Bierman, Stijn; Teal, Lorna R; Haenen, Olga; van de Vis, Hans; Rijnsdorp, Adriaan D

2013-01-01

Dover sole (Solea solea) is an obligate ectotherm with a natural thermal habitat ranging from approximately 5 to 27°C. Thermal optima for growth lie in the range of 20 to 25°C. More precise information on thermal optima for growth is needed for cost-effective Dover sole aquaculture. The main objective of this study was to determine the optimal growth temperature of juvenile Dover sole (Solea solea) and in addition to test the hypothesis that the final preferendum equals the optimal growth temperature. Temperature preference was measured in a circular preference chamber for Dover sole acclimated to 18, 22 and 28°C. Optimal growth temperature was measured by rearing Dover sole at 19, 22, 25 and 28°C. The optimal growth temperature resulting from this growth experiment was 22.7°C for Dover sole with a size between 30 to 50 g. The temperature preferred by juvenile Dover sole increases with acclimation temperature and exceeds the optimal temperature for growth. A final preferendum could not be detected. Although a confounding effect of behavioural fever on temperature preference could not be entirely excluded, thermal preference and thermal optima for physiological processes seem to be unrelated in Dover sole.

Best practices in managing child and adolescent behavioral health emergencies.

PubMed

Feuer, Vera; Rocker, Joshua; Saggu, Babar M; Andrus, Jason M

2018-01-01

Behavioral health emergencies most commonly present as depression, suicidal behavior, aggression, and severe disorganization. Emergency clinicians should avoid relying solely on past medical history or previous psychiatric diagnoses that might prematurely rule out medical pathologies. Treatments for behavioral health emergencies consist of de-escalation interventions aimed at preventing agitation, aggression, and harm. This issue reviews medical pathologies and underlying causes that can result in psychiatric presentations and summarizes evidence-based practices to evaluate, manage, and refer patients with behavioral health emergencies.

Making the Link. Coordinating Economic Development and Employment and Training. State Governments. Regional Councils. Local Economic Development Agencies.

ERIC Educational Resources Information Center

National Alliance of Business, Inc., Washington, DC.

This document consists of three closely related reports, dealing with "State Governments", "Regional Councils", and "Local Econcomic Development Agencies", respectively, together with a fourth document, a preceding overview. These documents draw from results of a project to identify successful approaches to coordinating economic development and…

Gender Differences in Reading Performance on Documents across Countries.

ERIC Educational Resources Information Center

Rosen, Monica

2001-01-01

Notes how females are known to excel over males in most reading tasks, but not consistently so in tasks that require processing information from maps, tables, charts and diagrams, so called "Documents." Describes and analyzes gender differences on Document tasks, and investigates if and how the pattern of differences varies over countries. (SG)

NASA Processes and Requirements for Conducting Human-in-the-Loop Closed Chamber Tests

NASA Technical Reports Server (NTRS)

Barta, Daniel J.; Montz, Michael E.

2004-01-01

NASA has specific processes and requirements that must be followed for tests involving human subjects to be conducted in a safe and effective manner. There are five distinct phases of test operations. Phase one, the test request phase, consists of those activities related to initiating, processing, reviewing, and evaluating the test request. Phase two, the test preparation phase consists of those activities related to planning, coordinating, documenting, and building up the test. Phase three, the test readiness phase consists of those activities related to verifying and reviewing the planned test operations. Phase four, the test activity phase, consists of all pretest operations, functional checkouts, emergency drills, and test operations. Phase five, the post test activity phase, consists of those activities performed once the test is completed, including briefings, documentation of anomalies, data reduction and archiving, and reporting. Project management processes must be followed for facility modifications and major test buildup, which include six phases: initiation and assessment, requirements evaluation, preliminary design, detailed design, use readiness review (URR) and acceptance. Compliance with requirements for safety and quality assurance are documented throughout the test buildup and test operation processes. Tests involving human subjects must be reviewed by the applicable Institutional Review Board (IRB).

Deriving Sediment Interstitial Water Remediation Goals ...

EPA Pesticide Factsheets

This document contains a methodology for developing interstitial water remediation goals (IWRGs) for nonionic organic pollutants (toxicants) in sediments for the protection of benthic organisms. The document provides the basis for using the final chronic values (FCVs) from EPA’s aquatic water quality criteria (AWQC) for the protection of aquatic life to set the IWRGs for toxicants in sediments. Concentrations of the toxicants in the sediment interstitial water are measured using passive sampling. This document also discusses how to evaluate the consistency between passive sampling measurements and sediment toxicity test results. When these data are consistent, one can be reasonably assured that the causes of toxicity to benthic organisms in the sediment have been correctly identified and that the developed IWRGs for the toxicants will be protective of the benthic organisms at the site. The consistency evaluation is an important step in developing defensible IWRGs. To assist in developing defensible IWRGs.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trewartha, Daniel; Kamleh, Waseem; Leinweber, Derek B.

The influence of centre vortices on dynamical chiral symmetry breaking is investigated through the light hadron spectrum on the lattice. Recent studies of the quark propagator and other quantities have provided evidence that centre vortices are the fundamental objects underpinning dynamical chiral symmetry breaking in SU(3) gauge theory. For the first time, we use the chiral overlap fermion action to study the low-lying hadron spectrum on lattice ensembles consisting of Monte Carlo, vortex-removed, and vortex-projected gauge fields. We find that gauge field configurations consisting solely of smoothed centre vortices are capable of reproducing all the salient features of the hadronmore » spectrum, including dynamical chiral symmetry breaking. In conclusion, the hadron spectrum on vortex-removed fields shows clear signals of chiral symmetry restoration at light values of the bare quark mass, while at heavy masses the spectrum is consistent with a theory of weakly-interacting constituent quarks.« less

Centre vortex removal restores chiral symmetry

NASA Astrophysics Data System (ADS)

Trewartha, Daniel; Kamleh, Waseem; Leinweber, Derek B.

2017-12-01

The influence of centre vortices on dynamical chiral symmetry breaking is investigated through the light hadron spectrum on the lattice. Recent studies of the quark propagator and other quantities have provided evidence that centre vortices are the fundamental objects underpinning dynamical chiral symmetry breaking in {SU}(3) gauge theory. For the first time, we use the chiral overlap fermion action to study the low-lying hadron spectrum on lattice ensembles consisting of Monte Carlo, vortex-removed, and vortex-projected gauge fields. We find that gauge field configurations consisting solely of smoothed centre vortices are capable of reproducing all the salient features of the hadron spectrum, including dynamical chiral symmetry breaking. The hadron spectrum on vortex-removed fields shows clear signals of chiral symmetry restoration at light values of the bare quark mass, while at heavy masses the spectrum is consistent with a theory of weakly interacting constituent quarks.

Coronary heart disease index based on longitudinal electrocardiography

NASA Technical Reports Server (NTRS)

Townsend, J. C.; Cronin, J. P.

1977-01-01

A coronary heart disease index was developed from longitudinal ECG (LCG) tracings to serve as a cardiac health measure in studies of working and, essentially, asymptomatic populations, such as pilots and executives. For a given subject, the index consisted of a composite score based on the presence of LCG aberrations and weighted values previously assigned to them. The index was validated by correlating it with the known presence or absence of CHD as determined by a complete physical examination, including treadmill, resting ECG, and risk factor information. The validating sample consisted of 111 subjects drawn by a stratified-random procedure from 5000 available case histories. The CHD index was found to be significantly more valid as a sole indicator of CHD than the LCG without the use of the index. The index consistently produced higher validity coefficients in identifying CHD than did treadmill testing, resting ECG, or risk factor analysis.

Centre vortex removal restores chiral symmetry

DOE PAGES

Trewartha, Daniel; Kamleh, Waseem; Leinweber, Derek B.

2017-11-15

The influence of centre vortices on dynamical chiral symmetry breaking is investigated through the light hadron spectrum on the lattice. Recent studies of the quark propagator and other quantities have provided evidence that centre vortices are the fundamental objects underpinning dynamical chiral symmetry breaking in SU(3) gauge theory. For the first time, we use the chiral overlap fermion action to study the low-lying hadron spectrum on lattice ensembles consisting of Monte Carlo, vortex-removed, and vortex-projected gauge fields. We find that gauge field configurations consisting solely of smoothed centre vortices are capable of reproducing all the salient features of the hadronmore » spectrum, including dynamical chiral symmetry breaking. In conclusion, the hadron spectrum on vortex-removed fields shows clear signals of chiral symmetry restoration at light values of the bare quark mass, while at heavy masses the spectrum is consistent with a theory of weakly-interacting constituent quarks.« less

Executive overview and introduction to the SMAP information system life-cycle and documentation standards

NASA Technical Reports Server (NTRS)

1989-01-01

An overview of the five volume set of Information System Life-Cycle and Documentation Standards is provided with information on its use. The overview covers description, objectives, key definitions, structure and application of the standards, and document structure decisions. These standards were created to provide consistent NASA-wide structures for coordinating, controlling, and documenting the engineering of an information system (hardware, software, and operational procedures components) phase by phase.

33 CFR 157.116 - Required documents: U.S. tank vessels.

Code of Federal Regulations, 2010 CFR

2010-07-01

... CARRYING OIL IN BULK Crude Oil Washing (COW) System on Tank Vessels General § 157.116 Required documents: U.S. tank vessels. The owner, operator, and master of a U.S. tank vessel having a COW system under... COW system consisting of— (1) A document from an authorized CS that certifies the vessel meets § 157...

Documenting Ground-Water Modeling at Sites Contaminated with Radioactive Substances

EPA Pesticide Factsheets

This report is the product of the Interagency Environmental Pathway Modeling Working Group. This report demonstrates how to document model applications in a consistent manner and is intended to assist technical staff.

Software Document Inventory Program

NASA Technical Reports Server (NTRS)

Merwarth, P. D.

1984-01-01

Program offers ways to file and locate sources of reference. DOCLIB system consists of two parts to serve needs of two type of users: general user and librarian. DOCLIB systems provides user with interactive, menudriven document inventory capability.

Offshore-onshore linkages in the larval life history of sole in the Gulf of Lions (NW-Mediterranean)

NASA Astrophysics Data System (ADS)

Morat, Fabien; Letourneur, Yves; Blamart, Dominique; Pécheyran, Christophe; Darnaude, Audrey M.; Harmelin-Vivien, Mireille

2014-08-01

Understanding individual dispersion from offshore natal areas to coastal nurseries during pelagic larval life is especially important for the sustainable management of exploited marine fish species. For several years, the hatching period, the larval life duration, the average growth rate and the otolith chemical composition (δ13C, δ18O, Sr:Ca and Ba:Ca) during the larval life were studied for young of the year (YOY) of sole collected in three main nurseries of the Gulf of Lions (GoL) (Thau, Mauguio and Berre). We investigated the spatial variation in the origin of the sole larvae which colonised the nurseries around the GoL, and whether temporal differences in environmental conditions during this life stage affected growth and larval life duration. The hatching period ranges from October to March, depending on year and site. Average ages at metamorphosis varied between 43 and 50 days, with the lowest and highest values consistently found for Mauguio and Berre, respectively. Otolith growth rates ranged between 2.7 and 3.2 μm d-1, with the lowest values in Thau and Mauguio and the highest in Berre. Otolith chemical composition during the larval life also varied, suggesting contrasted larval environmental histories in YOY among nurseries. In fishes from Berre and Mauguio, larval life was more influenced by the Rhône River, showing consistently higher larval Ba:Ca ratios (10/23 μmol mol-1) and lower δ13C (-6.5/-6.1‰) and δ18O values (-1.6/0.1‰) than for Thau (with Ba:Ca ratios < 8 μmol mol-1, δ13C ˜-2.3‰ and δ18O ˜1.5‰). Differences in larval otolith composition were observed for 2004, with higher Ba:Ca and lower δ13C and δ18O values than in the two other years. These differences were explained by changes in composition and chemical signatures of water masses after an exceptional flooding event of the Rhône River in late 2003.

Striking Distance Determined From High-Speed Videos and Measured Currents in Negative Cloud-to-Ground Lightning

NASA Astrophysics Data System (ADS)

Visacro, Silverio; Guimaraes, Miguel; Murta Vale, Maria Helena

2017-12-01

First and subsequent return strokes' striking distances (SDs) were determined for negative cloud-to-ground flashes from high-speed videos exhibiting the development of positive and negative leaders and the pre-return stroke phase of currents measured along a short tower. In order to improve the results, a new criterion was used for the initiation and propagation of the sustained upward connecting leader, consisting of a 4 A continuous current threshold. An advanced approach developed from the combined use of this criterion and a reverse propagation procedure, which considers the calculated propagation speeds of the leaders, was applied and revealed that SDs determined solely from the first video frame showing the upward leader can be significantly underestimated. An original approach was proposed for a rough estimate of first strokes' SD using solely records of current. This approach combines the 4 A criterion and a representative composite three-dimensional propagation speed of 0.34 × 106 m/s for the leaders in the last 300 m propagated distance. SDs determined under this approach showed to be consistent with those of the advanced procedure. This approach was applied to determine the SD of 17 first return strokes of negative flashes measured at MCS, covering a wide peak-current range, from 18 to 153 kA. The estimated SDs exhibit very high dispersion and reveal great differences in relation to the SDs estimated for subsequent return strokes and strokes in triggered lightning.

Oman metamorphic sole formation reveals early subduction dynamics

NASA Astrophysics Data System (ADS)

Soret, Mathieu; Agard, Philippe; Dubacq, Benoît; Plunder, Alexis; Ildefonse, Benoît; Yamato, Philippe; Prigent, Cécile

2016-04-01

Metamorphic soles correspond to m to ~500m thick tectonic slices welded beneath most of the large-scale ophiolites. They typically show a steep inverted metamorphic structure where the pressure and temperature conditions of crystallization increase upward (from 500±100°C at 0.5±0.2 GPa to 800±100°C at 1.0±0.2 GPa), with isograds subparallel to the contact with the overlying ophiolitic peridotite. The proportion of mafic rocks in metamorphic soles also increases from the bottom (meta-sediments rich) to the top (approaching the ophiolite peridotites). These soles are interpreted as the result of heat transfer from the incipient mantle wedge toward the nascent slab (associated with large-scale fluid transfer and possible shear heating) during the first My of intra-oceanic subduction (as indicated by radiometric ages). Metamorphic soles provide therefore major constraints on early subduction dynamics (i.e., thermal structure, fluid migration and rheology along the nascent slab interface). We present a detailed structural and petrological study of the metamorphic sole from 4 major cross-sections along the Oman ophiolite. We show precise pressure-temperature estimates obtained by pseudosection modelling and EBSD measurements performed on both the garnet-bearing and garnet-free high-grade sole. Results allow quantification of the micro-scale deformation and highlight differences in pressure-temperature-deformation conditions between the 4 different locations, showing that the inverted metamorphic gradient through the sole is not continuous in all locations. Based on these new constraints, we suggest a new tectonic-petrological model for the formation of metamorphic soles below ophiolites. This model involves the stacking of several homogeneous slivers of oceanic crust leading to the present-day structure of the sole. In this view, these thrusts are the result of rheological contrasts between the sole and the peridotite as the plate interface progressively cools down. These slivers later underwent several stages of retrogression (partly mediated by ascending fluids from the slab) from amphibolite- to prehnite/pumpellite-facies conditions.

Good practices for common sole assessment in the Adriatic Sea: Genetic and morphological differentiation of Solea solea (Linnaeus, 1758) from S. aegyptiaca (Chabanaud, 1927) and stock identification

NASA Astrophysics Data System (ADS)

Sabatini, Laura; Bullo, Marianna; Cariani, Alessia; Celić, Igor; Ferrari, Alice; Guarniero, Ilaria; Leoni, Simone; Marčeta, Bojan; Marcone, Alessandro; Polidori, Piero; Raicevich, Saša; Tinti, Fausto; Vrgoč, Nedo; Scarcella, Giuseppe

2018-07-01

In the Adriatic Sea two cryptic species of sole coexist, the common and Egyptian sole. Soles are one of the most valuable demersal fishery resources in the Adriatic Sea, so a correct species identification is crucial in order to perform stock assessment and implement effective management measures based on reliable and accurate data. In this study specimens collected during fishery-independent and fishery-dependent activities in the Adriatic were analyzed and identified coupling morphological and genetic approaches. A comparison of these two methods for the sole species identification was carried out to assess the most effective, accurate and practical diagnostic morphological key-character(s). Results showed that external characters, in particular features of the posterior dorsal and anal fins, are valid and accurate morphological markers. Based on these traits, a practical identification key of the two sibling species was proposed. Moreover, it was possible to estimate the extent of the error due to species misidentification introduced in the common sole stock assessment carried out in the Northern-central Adriatic Sea (GSA17). A 5% bias in the correct identification of common sole specimens was detected. However, this bias was shown not to affect the common sole stock assessment. Moreover, the genetic profiling of the Adriatic common sole allowed estimating genetic diversity and assessing population structure. Significant divergence between common soles inhabiting the eastern part of the Southern Adriatic Sea and those collected from the other areas of the basin was confirmed. Therefore, the occurrence of genetically differentiated subpopulations supports the need to implement independent stock assessments and management measures.

Evaluation of design consistency methods for two-lane rural highways : executive summary

DOT National Transportation Integrated Search

2000-08-01

Design consistency refers to the conformance of a highway's geometry with driver expectancy. Techniques to evaluate the consistency of a design documented within this report include speed-profile model, alignment indices, speed distribution measures,...

Studies on graphene zinc-oxide nanocomposites photoanodes for high-efficient dye-sensitized solar cells

NASA Astrophysics Data System (ADS)

Effendi, N. A. S.; Samsi, N. S.; Zawawi, S. A.; Hassan, O. H.; Zakaria, R.; Yahya, M. Z. A.; Ali, A. M. M.

2017-09-01

A dye-sensitized solar cells (DSSCs) using a nanocomposite (NC) semiconductor film, consisting of graphene layer and ZnO nanosheets (Gr-ZnO) is fabricated by electrodeposition process. The DSSCs based on Gr-ZnO NC were determined via electrochemical impedance spectra (EIS), UV-Visible diffused reflectance spectroscopy (UV-Vis), and photovoltaic performances J-V curves to substantiate the explanations. Impedance spectra shows that a smaller charge transport time constant occurs in DSSCs based on Gr-ZnO NC comparing to ZnO. This improved the electron collecting efficiency significantly, resulting in high open circuit voltage. Moreover, Gr-ZnO NC shows an efficient photoinduced charge separation and transportation can be achieved at the interface thus exhibit excellent potential for photocurrent generation compared with sole ZnO. Gr-ZnO NC obtained a maximum photocurrent response for an open-circuit voltage and a power conversion efficiency of 0.96 V and 7.01% respectively, which is doubled from sole ZnO. The fabricated Gr-ZnO NC cells show better performances compared to conventional ZnO structure reference cell.

Flatfish recruitment response to decadal climatic variability and ocean conditions in the eastern Bering Sea

NASA Astrophysics Data System (ADS)

Wilderbuer, T. K.; Hollowed, A. B.; Ingraham, W. J.; Spencer, P. D.; Conners, M. E.; Bond, N. A.; Walters, G. E.

2002-10-01

This paper provides a retrospective analysis of the relationship of physical oceanography and biology and recruitment of three Eastern Bering Sea flatfish stocks: flathead sole ( Hippoglossoides elassodon), northern rock sole ( Lepidopsetta polyxystra), and arrowtooth flounder ( Atheresthes stomias) for the period 1978-1996. Temporal trends in flatfish production in the Eastern Bering Sea are consistent with the hypothesis that decadal scale climate variability influences marine survival during the early life history period. Density-dependence (spawning stock size) is statistically significant in a Ricker model of flatfish recruitment, which includes environmental terms. Wind-driven advection of flatfish larvae to favorable nursery grounds was also found to coincide with years of above-average recruitment through the use of an ocean surface current simulation model (OSCURS). Ocean forcing of Bristol Bay surface waters during springtime was mostly shoreward (eastward) during the 1980s and seaward (westerly) during the 1990s, corresponding with periods of good and poor recruitment. Distance from shore and water depth at the endpoint of 90-day drift periods (estimated time of settlement) were also found to correspond with flatfish productivity.

Quarantine document system indexing procedure

NASA Technical Reports Server (NTRS)

1972-01-01

The Quarantine Document System (QDS) is described including the indexing procedures and thesaurus of indexing terms. The QDS consists of these functional elements: acquisition, cataloging, indexing, storage, and retrieval. A complete listing of the collection, and the thesaurus are included.

Specification of the Transmitted Signal of the Omega Navigation System.

DOT National Transportation Integrated Search

1984-01-01

This report documents the specification of the transmitted signal to the OMEGA Navigation System. It is intended as a reference document consisting of specifications, definitions, and explanations for general use by designers, manufacturers, and user...

Native American prehistory of the middle Savannah River Valley

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sassaman, K.E.; Brooks, M.J.; Hanson, G.T.

1990-01-01

Archaeological investigations on the United States Department of Energy's (DOE) Savannah River Site (SRS) in South Carolina span 17 years and continue today through a cooperative agreement between DOE and the South Carolina Institute of Archaeology and Anthropology (SCIAA), University of South Carolina. The Savannah River Archaeological Research Program (SRARP) of SCIAA has been and continues to be the sole archaeological consultant for DOE-SRS. This report documents technical aspects of all prehistoric archaeological research conducted by the SRARP between 1973 and 1987. Further, this report provides interpretative contexts for archaeological resources as a basis for an archaeological resource plan reportedmore » elsewhere (SRARP 1989), and as a comprehensive statement of our current understanding of Native American prehistory. 400 refs., 130 figs., 39 tabs.« less

Child accident prevention as a health promotion issue--how extensive is the problem and how far have A & E departments responded to the recommendations made?

PubMed

Ferguson, A

1994-10-01

Accidents to children are always a source of concern to any health care professional. Despite the wealth of evidence that suggests many of these accidents are preventable, the numbers of deaths and long-term disability have remained fairly constant. It would appear that only if all agencies and authorities who have a responsibility for the health and safety of children work closely together, to educate those caring for children, enforce legislation and pressure governments to improve the child's environment, will a dramatic reduction in accidents be achieved. Despite this, the Health of the Nation document looks solely towards an educational approach aimed at the general public with no apparent thought as to the effectiveness of this strategy.

Characterization Results for the March 2016 H-Tank Farm 2H Evaporator Overhead Samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nicholson, J. C.

This report contains the radioanalytical results of the 2H evaporator overhead sample received at SRNL on March 16, 2016. Specifically, concentrations of 137Cs, 90Sr, and 129I are reported and compared to the corresponding Waste Acceptance Criteria (WAC) limits of the Effluent Treatment Project (ETP) Waste Water Collection Tank (WWCT) (rev. 6). All of the radionuclide concentrations in the sample were found to be in compliance with the ETP WAC limits. Revision 1 of this document corrects the cumulative beta count initially reported for 90Sr content with the sole 90Sr count obtained after recharacterization of the sample. The initial data wasmore » found to be a cumulative beta count rather than the 90Sr count requested.« less

Uses of software in digital image analysis: a forensic report

NASA Astrophysics Data System (ADS)

Sharma, Mukesh; Jha, Shailendra

2010-02-01

Forensic image analysis is required an expertise to interpret the content of an image or the image itself in legal matters. Major sub-disciplines of forensic image analysis with law enforcement applications include photo-grammetry, photographic comparison, content analysis and image authentication. It has wide applications in forensic science range from documenting crime scenes to enhancing faint or indistinct patterns such as partial fingerprints. The process of forensic image analysis can involve several different tasks, regardless of the type of image analysis performed. Through this paper authors have tried to explain these tasks, which are described in to three categories: Image Compression, Image Enhancement & Restoration and Measurement Extraction. With the help of examples like signature comparison, counterfeit currency comparison and foot-wear sole impression using the software Canvas and Corel Draw.

TERMTrial--terminology-based documentation systems for cooperative clinical trials.

PubMed

Merzweiler, A; Weber, R; Garde, S; Haux, R; Knaup-Gregori, P

2005-04-01

Within cooperative groups of multi-center clinical trials a standardized documentation is a prerequisite for communication and sharing of data. Standardizing documentation systems means standardizing the underlying terminology. The management and consistent application of terminology systems is a difficult and fault-prone task, which should be supported by appropriate software tools. Today, documentation systems for clinical trials are often implemented as so-called Remote-Data-Entry-Systems (RDE-systems). Although there are many commercial systems, which support the development of RDE-systems there is none offering a comprehensive terminological support. Therefore, we developed the software system TERMTrial which consists of a component for the definition and management of terminology systems for cooperative groups of clinical trials and two components for the terminology-based automatic generation of trial databases and terminology-based interactive design of electronic case report forms (eCRFs). TERMTrial combines the advantages of remote data entry with a comprehensive terminological control.

Considerations regarding the deployment of hypermedia at JSC

NASA Technical Reports Server (NTRS)

Kacmar, Charles J.

1993-01-01

Electronic documents and systems are becoming the primary means of managing information for ground and space operations at NASA. These documents will utilize hypertext and hypermedia technologies to aid users in structuring and accessing information. Documents will be composed of static and dynamic data consisting of user-defined annotations and hypermedia links. The report consists of three major sections. First, it provides an overview of hypermedia and surveys the use of hypermedia throughout JSC. Second, it briefly describes a prototypical hypermedia system that was developed in conjunction with this work. This system was constructed to demonstrate various hypermedia features and to serve as a platform for supporting the electronic documentation needs for the MIDAS system developed by the Intelligent Systems Branch of the Automation and Robotics Division (Pac92). Third, it discusses emerging hypermedia technologies which have either been untapped by vendors or present significant challenges to the Agency.

Successful Treatment of Plantar Hyperkeratosis in the Form of Recurrent Corns With Split-Thickness Sole Skin Graft.

PubMed

Wang, Chi-Yu; Chang, Chun-Kai; Chou, Chang-Yi; Wu, Chien-Ju; Chu, Tzi-Shiang; Chiao, Hao-Yu; Chen, Chun-Yu; Chen, Tim-Mo; Tzeng, Yuan-Sheng

2018-02-01

Plantar hyperkeratosis, such as corns and calluses, is common in older people and associated with pain, mobility impairment, and functional limitations. It usually develops on the palms, knees, or soles of feet, especially under the heels or balls. There are several treatment methods for plantar hyperkeratosis, such as salicylic acid plaster and scalpel debridement, and conservative modalities, such as using a shoe insert and properly fitting shoes. We present an effective method of reconstructing the wound after corn excision using a split-thickness sole skin graft (STSSG). We harvested the skin graft from the arch of the sole using the dermatome with a skin thickness of 14/1000th inches. Because the split-thickness skin graft, harvested from the sole arch near the distal sole, is much thicker than the split-thickness skin graft from the thigh, it is more resistant to weight and friction. The healed wound with STSSG coverage over the distal sole was intact, and the donor site over the sole arch had healed without complication during the outpatient follow-up, 3 months after surgery. The recovery time of STSSG for corn excision is shorter than that with traditional treatment. Therefore, STSSG can be a reliable alternative treatment for recurrent palmoplantar hyperkeratosis.

An Efficient Approach for Web Indexing of Big Data through Hyperlinks in Web Crawling.

PubMed

Devi, R Suganya; Manjula, D; Siddharth, R K

2015-01-01

Web Crawling has acquired tremendous significance in recent times and it is aptly associated with the substantial development of the World Wide Web. Web Search Engines face new challenges due to the availability of vast amounts of web documents, thus making the retrieved results less applicable to the analysers. However, recently, Web Crawling solely focuses on obtaining the links of the corresponding documents. Today, there exist various algorithms and software which are used to crawl links from the web which has to be further processed for future use, thereby increasing the overload of the analyser. This paper concentrates on crawling the links and retrieving all information associated with them to facilitate easy processing for other uses. In this paper, firstly the links are crawled from the specified uniform resource locator (URL) using a modified version of Depth First Search Algorithm which allows for complete hierarchical scanning of corresponding web links. The links are then accessed via the source code and its metadata such as title, keywords, and description are extracted. This content is very essential for any type of analyser work to be carried on the Big Data obtained as a result of Web Crawling.

An Efficient Approach for Web Indexing of Big Data through Hyperlinks in Web Crawling

PubMed Central

Devi, R. Suganya; Manjula, D.; Siddharth, R. K.

2015-01-01

Web Crawling has acquired tremendous significance in recent times and it is aptly associated with the substantial development of the World Wide Web. Web Search Engines face new challenges due to the availability of vast amounts of web documents, thus making the retrieved results less applicable to the analysers. However, recently, Web Crawling solely focuses on obtaining the links of the corresponding documents. Today, there exist various algorithms and software which are used to crawl links from the web which has to be further processed for future use, thereby increasing the overload of the analyser. This paper concentrates on crawling the links and retrieving all information associated with them to facilitate easy processing for other uses. In this paper, firstly the links are crawled from the specified uniform resource locator (URL) using a modified version of Depth First Search Algorithm which allows for complete hierarchical scanning of corresponding web links. The links are then accessed via the source code and its metadata such as title, keywords, and description are extracted. This content is very essential for any type of analyser work to be carried on the Big Data obtained as a result of Web Crawling. PMID:26137592

A Comparison of Product Realization Frameworks

DTIC Science & Technology

1993-10-01

software (integrated FrameMaker ). Also included are BOLD for on-line documentation delivery, printer/plotter support, and 18 network licensing support. AMPLE...are built with DSS. Documentation tools include an on-line information system (BOLD), text editing (Notepad), word processing (integrated FrameMaker ...within an application. FrameMaker is fully integrated with the Falcon Framework to provide consistent documentation capabilities within engineering

EPA Determination Regarding the Consistency of the Elmendorf ENVVEST/XL Project Proposal and EPA's Guidance for Military Installations

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Inadequate thickness of the weight-bearing surface of claws in ruminants.

PubMed

Shakespeare, A S

2009-12-01

The term 'thin soles' refers to the suboptimal thickness of the weight-bearing surface of claws in ruminants. These palmar/plantar surfaces of the claws support the weight of the animal and consist of the distal wall horn, the sole proper, the heel and the minute white line area. The sole should normally only bear weight on uneven or undulating surfaces. A decrease in the thickness of the weight-bearing claw surface will decrease the protective function of this structure and may alter the proportion of weight-bearing by each section with possible detrimental effects on hoof function. Horn tissue readily absorbs water and becomes softer which can lead to increased wear rates. Growth rates normally match wear rates but, unlike the latter, time is needed for the growth rate response to adapt to changes in wear rate. Concrete surfaces can be abrasive and dairy cows that spend their lactation cycle on these floors should be let out to pasture in the dry period so that their claws can recoup lost horn. Frictional coefficient is a measure of the'slipperiness' of hooves on various surfaces. Newly laid or fresh concrete is not only abrasive but the thin surface suspension of calcium hydroxide that forms has a very alkaline pH which causes keratin degradation and is mostly responsible for the excessive claw wear that occurs. Four case studies are used to illustrate the importance of the distal wall horn, the dangers of over-trimming and the effects of disease and concrete on horn growth and wear rates.

Climate mediates hypoxic stress on fish diversity and nursery function at the land-sea interface.

PubMed

Hughes, Brent B; Levey, Matthew D; Fountain, Monique C; Carlisle, Aaron B; Chavez, Francisco P; Gleason, Mary G

2015-06-30

Coastal ecosystems provide numerous important ecological services, including maintenance of biodiversity and nursery grounds for many fish species of ecological and economic importance. However, human population growth has led to increased pollution, ocean warming, hypoxia, and habitat alteration that threaten ecosystem services. In this study, we used long-term datasets of fish abundance, water quality, and climatic factors to assess the threat of hypoxia and the regulating effects of climate on fish diversity and nursery conditions in Elkhorn Slough, a highly eutrophic estuary in central California (United States), which also serves as a biodiversity hot spot and critical nursery grounds for offshore fisheries in a broader region. We found that hypoxic conditions had strong negative effects on extent of suitable fish habitat, fish species richness, and abundance of the two most common flatfish species, English sole (Parophrys vetulus) and speckled sanddab (Citharichthys stigmaeus). The estuary serves as an important nursery ground for English sole, making this species vulnerable to anthropogenic threats. We determined that estuarine hypoxia was associated with significant declines in English sole nursery habitat, with cascading effects on recruitment to the offshore adult population and fishery, indicating that human land use activities can indirectly affect offshore fisheries. Estuarine hypoxic conditions varied spatially and temporally and were alleviated by strengthening of El Niño conditions through indirect pathways, a consistent result in most estuaries across the northeast Pacific. These results demonstrate that changes to coastal land use and climate can fundamentally alter the diversity and functioning of coastal nurseries and their adjacent ocean ecosystems.

Climate mediates hypoxic stress on fish diversity and nursery function at the land–sea interface

PubMed Central

Hughes, Brent B.; Levey, Matthew D.; Fountain, Monique C.; Carlisle, Aaron B.; Chavez, Francisco P.; Gleason, Mary G.

2015-01-01

Coastal ecosystems provide numerous important ecological services, including maintenance of biodiversity and nursery grounds for many fish species of ecological and economic importance. However, human population growth has led to increased pollution, ocean warming, hypoxia, and habitat alteration that threaten ecosystem services. In this study, we used long-term datasets of fish abundance, water quality, and climatic factors to assess the threat of hypoxia and the regulating effects of climate on fish diversity and nursery conditions in Elkhorn Slough, a highly eutrophic estuary in central California (United States), which also serves as a biodiversity hot spot and critical nursery grounds for offshore fisheries in a broader region. We found that hypoxic conditions had strong negative effects on extent of suitable fish habitat, fish species richness, and abundance of the two most common flatfish species, English sole (Parophrys vetulus) and speckled sanddab (Citharichthys stigmaeus). The estuary serves as an important nursery ground for English sole, making this species vulnerable to anthropogenic threats. We determined that estuarine hypoxia was associated with significant declines in English sole nursery habitat, with cascading effects on recruitment to the offshore adult population and fishery, indicating that human land use activities can indirectly affect offshore fisheries. Estuarine hypoxic conditions varied spatially and temporally and were alleviated by strengthening of El Niño conditions through indirect pathways, a consistent result in most estuaries across the northeast Pacific. These results demonstrate that changes to coastal land use and climate can fundamentally alter the diversity and functioning of coastal nurseries and their adjacent ocean ecosystems. PMID:26056293

Transportation management center data capture for performance and mobility measures guidebook.

DOT National Transportation Integrated Search

2013-03-01

The Guide to Transportation Management Center (TMC) Data Capture for Performance and Mobility Measures is a two-volume document consisting of this summary Guidebook and a Reference Manual. These documents provide technical guidance and recommended pr...

Electrolytic photodissociation of chemical compounds by iron oxide electrodes

DOEpatents

Somorjai, Gabor A.; Leygraf, Christofer H.

1984-01-01

Chemical compounds can be dissociated by contacting the same with a p/n type semi-conductor diode having visible light as its sole source of energy. The diode consists of low cost, readily available materials, specifically polycrystalline iron oxide doped with silicon in the case of the n-type semi-conductor electrode, and polycrystalline iron oxide doped with magnesium in the case of the p-type electrode. So long as the light source has an energy greater than 2.2 electron volts, no added energy source is needed to achieve dissociation.

Electrolytic photodissociation of chemical compounds by iron oxide photochemical diodes

DOEpatents

Somorjai, Gabor A.; Leygraf, Christofer H.

1985-01-01

Chemical compounds can be dissociated by contacting the same with a p/n type semi-conductor photochemical diode having visible light as its sole source of energy. The photochemical diode consists of low cost, readily available materials, specifically polycrystalline iron oxide doped with silicon in the case of the n-type semi-conductor electrode, and polycrystalline iron oxide doped with magnesium in the case of the p-type electrode. So long as the light source has an energy greater than 2.2 electron volts, no added energy source is needed to achieve dissociation.

Plasmon analysis and homogenization in plane layered photonic crystals and hyperbolic metamaterials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davidovich, M. V., E-mail: davidovichmv@info.sgu.ru

2016-12-15

Dispersion equations are obtained and analysis and homogenization are carried out in periodic and quasiperiodic plane layered structures consisting of alternating dielectric layers, metal and dielectric layers, as well as graphene sheets and dielectric (SiO{sub 2}) layers. Situations are considered when these structures acquire the properties of hyperbolic metamaterials (HMMs), i.e., materials the real parts of whose effective permittivity tensor have opposite signs. It is shown that the application of solely dielectric layers is more promising in the context of reducing losses.

Reduction of blood serum cholesterol

NASA Technical Reports Server (NTRS)

Winitz, M. (Inventor)

1974-01-01

By feeding a human subject as the sole source of sustenance a defined diet wherein the carbohydrate consists substantially entirely of glucose, maltose or a polysaccharide of glucose, the blood serum cholesterol level of the human subject is substantially reduced. If 25 percent of the carbohydrate is subsequently supplied in the form of sucrose, an immediate increase from the reduced level is observed. The remainder of the defined diet normally includes a source of amino acids, such as protein or a protein hydrolysate, vitamins, minerals and a source of essential fatty acid.

VizieR Online Data Catalog: Binarity in planetary nebula central stars (De Marco+ 2013)

NASA Astrophysics Data System (ADS)

De Marco O.; Passy, J.-C.; Frew, D. J.; Moe, M.; Jacoby, G. H.

2014-01-01

The sample presented here consists of 30 central stars of PN which were selected solely based on their low PN surface brightness (radius of the PN is larger than ~25arcsec in most cases) as well as on the faint V magnitudes of their central stars. The observations were acquired during eight nights between 2007 October 30 and November 6 at the 2.1-m telescope at the Kitt Peak National Observatory. However, the data from nights 2 and 8 were not photometric. (5 data files).

Observations on plantlore in Buldhana District of Maharashtra

PubMed Central

Patil, P.S.; Dushing, Y.A.; Patil, D.A.

2007-01-01

Traditional medicinal uses for various human diseases of 54 angiospermic species from Shegaon, Sangrampur, Jalgaon (Jamod), Malkapur, Nandura, Motala and Khamgaon tehsils of Buldhana district (Maharashtra) are reported. Of these, applications of 36 species are unknown or little known. The folk medicines consist of a sole drug or a principal drug in combination with other drugs. The recent botanical name, local plant name, recipe, mode of administration, doses etc. are communicated as collected from the tribal and rural folks of the district. It is desirable to screen these species on modern scientific lines. PMID:22557259

Observations on plantlore in Buldhana District of Maharashtra.

PubMed

Patil, P S; Dushing, Y A; Patil, D A

2007-07-01

Traditional medicinal uses for various human diseases of 54 angiospermic species from Shegaon, Sangrampur, Jalgaon (Jamod), Malkapur, Nandura, Motala and Khamgaon tehsils of Buldhana district (Maharashtra) are reported. Of these, applications of 36 species are unknown or little known. The folk medicines consist of a sole drug or a principal drug in combination with other drugs. The recent botanical name, local plant name, recipe, mode of administration, doses etc. are communicated as collected from the tribal and rural folks of the district. It is desirable to screen these species on modern scientific lines.

Best practices in managing child and adolescent behavioral health emergencies [digest].

PubMed

Feuer, Vera; Rocker, Joshua; Saggu, Babar M; Andrus, Jason M; Wormley, Molly

2018-01-22

Behavioral health emergencies most commonly present as depression, suicidal behavior, aggression, and severe disorganization. Emergency clinicians should avoid relying solely on past medical history or previous psychiatric diagnoses that might prematurely rule out medical pathologies. Treatments for behavioral health emergencies consist of de-escalation interventions aimed at preventing agitation, aggression, and harm. This issue reviews medical pathologies and underlying causes that can result in psychiatric presentations and summarizes evidence-based practices to evaluate, manage, and refer patients with behavioral health emergencies. [Points & Pearls is a digest of Pediatric Emergency Medicine Practice].

Development towards a fast ion loss detector for the reversed field pinch.

PubMed

Bonofiglo, P J; Anderson, J K; Almagri, A F; Kim, J; Clark, J; Capecchi, W; Sears, S H; Egedal, J

2016-11-01

A fast ion loss detector has been constructed and implemented on the Madison Symmetric Torus (MST) to investigate energetic ion losses and transport due to energetic particle and MHD instabilities. The detector discriminates particle orbits solely on pitch and consists of two thin-foil, particle collecting plates that are symmetric with respect to the device aperture. One plate collects fast ion signal, while the second aids in the minimization of background and noise effects. Initial measurements are reported along with suggestions for the next design phase of the detector.

Overview of the TREC 2008 Legal Track

DTIC Science & Technology

2008-11-01

CDIP ) Test Collection, version 1.0 (referred to here as “IIT CDIP 1.0”) which is based on documents released under the tobacco “Master Settlement...repository, the Legacy Tobacco Documents Library (LTDL), for tobacco documents [9]. The IIT CDIP 1.0 collection is based on a snapshot, generated between...November 2005 and January 2006, of the MSA subcollection of the LTDL. The IIT CDIP 1.0 collection consists of 6,910,192 document records in the form of

NLS Flight Simulation Laboratory (FSL) documentation

NASA Technical Reports Server (NTRS)

1995-01-01

The Flight Simulation Laboratory (FSL) Electronic Documentation System design consists of modification and utilization of the MSFC Integrated Engineering System (IES), translation of the existing FSL documentation to an electronic format, and generation of new drawings to represent the Engine Flight Simulation Laboratory design and implementation. The intent of the electronic documentation is to provide ease of access, local print/plot capabilities, as well as the ability to correct and/or modify the stored data by network users who are authorized to access this information.

TWRS technical baseline database manager definition document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Acree, C.D.

1997-08-13

This document serves as a guide for using the TWRS Technical Baseline Database Management Systems Engineering (SE) support tool in performing SE activities for the Tank Waste Remediation System (TWRS). This document will provide a consistent interpretation of the relationships between the TWRS Technical Baseline Database Management software and the present TWRS SE practices. The Database Manager currently utilized is the RDD-1000 System manufactured by the Ascent Logic Corporation. In other documents, the term RDD-1000 may be used interchangeably with TWRS Technical Baseline Database Manager.

Methods of Sparse Modeling and Dimensionality Reduction to Deal with Big Data

DTIC Science & Technology

2015-04-01

supervised learning (c). Our framework consists of two separate phases: (a) first find an initial space in an unsupervised manner; then (b) utilize label...model that can learn thousands of topics from a large set of documents and infer the topic mixture of each document, 2) a supervised dimension reduction...model that can learn thousands of topics from a large set of documents and infer the topic mixture of each document, (i) a method of supervised

The effect of roughness, floor polish, water, oil and ice on underfoot friction: current safety footwear solings are less slip resistant than microcellular polyurethane.

PubMed

Manning, D P; Jones, C

2001-04-01

Research over a period of about 18 years has shown that a microcellular polyurethane known as AP66033 is the most slip-resistant safety footwear soling material on oily and wet surfaces. In recent years it has been replaced in commercially available footwear by a dual density polyurethane (DDP) which has a dense outer layer and a soft microcellular backing. This research programme has compared the slip resistance of AP66033 with DDP and some rubber solings. In addition, data were obtained on the effects of soling and floor roughness, and floor polish on slip resistance. Some data were also obtained for walking on ice. The coefficient of friction (CoF) of the solings was measured on 19 water wet surfaces in three conditions: (I) when the solings were new, (II) following abrasion to create maximum roughness and (III) after polishing. The CoF was measured on four oily surfaces after each of 11 abrasion or polishing treatments. The profound effects of the roughening of all soles and of floor roughness on the CoF were demonstrated for both wet and oily surfaces. The superior slip resistance of AP66033 was confirmed for oily and wet conditions; however, some rubbers not suitable for safety footwear achieved higher CoF values on wet floors. All of the floor polishes reduced the CoF of all floors when contaminated with water. The mean CoF of DDP solings was lower than the mean for AP66033 on wet and oily surfaces. No safety footwear soling provided adequate grip on dry ice and the CoF was reduced by water on the ice. A rubber used for rock climbing footwear was one of the most slip-resistant solings on wet surfaces in the laboratory but recorded the lowest CoF on ice. It is concluded that the incidence of occupational injuries caused by slipping could be reduced by the following: (A) returning to safety footwear soled with the microcellular polyurethane AP66033; (B) abrading all new and smooth footwear solings with a belt sanding machine coated with P100 grit; (C) avoiding the use of floor polish; (D) informing the general public about the poor slip resistance of ordinary footwear on ice and the lowering of slip resistance in cold weather.

Digital photo documentation of forensically relevant injuries as part of the clinical first response protocol.

PubMed

Verhoff, Marcel A; Kettner, Mattias; Lászik, András; Ramsthaler, Frank

2012-09-01

A problem encountered by medical examiners is that they have to assess injuries that have already been medically treated. Thus, they have to base their reports on clinical forensic examinations performed hours or days after an injury was sustained, or even base their assessment solely on information gleaned from medical files. In both scenarios, the forensic examiner has to rely heavily on the first responder's documentation of the original injury pattern. Medical priority will be to immediately treat a patient's injuries, and the first responder may, in addition, initially be unaware of a possibly criminal origin of an injury. As a result, the documentation of injuries is frequently of limited value for forensic purposes. This situation could be improved if photographic records were briefly made of injuries before they were treated. German-language medicolegal, criminal, and photography journals and books were selectively searched with the help of PubMed and other databases. In addition, the authors' experiences in creating and evaluating photographic records for clinical forensic use were assessed. This paper is an aid to creating photographic records of sufficient quality for forensic purposes. The options provided by digital photography in particular make this endeavor feasible even in a clinical setting. In addition, our paper illuminates some technical aspects of creating and archiving photographic records for forensic use, and addresses possible error sources. With the requisite technical background knowledge, injuries can be photographically recorded to forensic standards during patient care.

EPA Region 1 Sole Source Aquifers

EPA Pesticide Factsheets

This coverage contains boundaries of EPA-approved sole source aquifers. Sole source aquifers are defined as an aquifer designated as the sole or principal source of drinking water for a given aquifer service area; that is, an aquifer which is needed to supply 50% or more of the drinking water for the area and for which there are no reasonable alternative sources should the aquifer become contaminated.The aquifers were defined by a EPA hydrogeologist. Aquifer boundaries were then drafted by EPA onto 1:24000 USGS quadrangles. For the coastal sole source aquifers the shoreline as it appeared on the quadrangle was used as a boundary. Delineated boundaries were then digitized into ARC/INFO.

Crystal field effect in light actinide dioxides and oxychalcogenides-a unified phenomenological description

NASA Astrophysics Data System (ADS)

Gajek, Z.

2004-05-01

The electronic properties of the actinide ions in the series of semi-conducting, antiferromagnetic compounds: dioxides, AnO2 and oxychalcogenides, AnOY, where An=U, Np and Y=S, Se, are re-examined from the point of view of the consistency of the crystal field (CF) model. The discussion is based on the supposition that the effective metal-ligand interaction solely determines the net CF effect in non-metallic compounds. The main question we address here is, whether a reliable, consistent description of the CF effect in terms of the intrinsic parameters can be achieved for this particular family of compounds. Encouraging calculations reported previously for the AnO2 and UOY series serve as a reference data in the present estimation of electronic structure parameters for neptunium oxychalcogenides.

Hematopoietic stem cell origin of connective tissues.

PubMed

Ogawa, Makio; Larue, Amanda C; Watson, Patricia M; Watson, Dennis K

2010-07-01

Connective tissue consists of "connective tissue proper," which is further divided into loose and dense (fibrous) connective tissues and "specialized connective tissues." Specialized connective tissues consist of blood, adipose tissue, cartilage, and bone. In both loose and dense connective tissues, the principal cellular element is fibroblasts. It has been generally believed that all cellular elements of connective tissue, including fibroblasts, adipocytes, chondrocytes, and bone cells, are generated solely by mesenchymal stem cells. Recently, a number of studies, including those from our laboratory based on transplantation of single hematopoietic stem cells, strongly suggested a hematopoietic stem cell origin of these adult mesenchymal tissues. This review summarizes the experimental evidence for this new paradigm and discusses its translational implications. Copyright 2010 ISEH - Society for Hematology and Stem Cells. All rights reserved.

Sole Community Hospitals: Are They Different? A Statistical Analysis of the Hospitals and Their Treatment under TEFRA and PPS. Hospital Studies Program. Hospital Cost and Utilization Project. Research Note 5.

ERIC Educational Resources Information Center

Farley, Dean E.

A study examined the treatment of sole community hospitals under the Tax Equity and Fiscal Responsibility Act of 1982 (TEFRA) and the Prospective Payment System (PPS) for Medicare as compared to the treatment of hospitals not designated as sole community hospitals under these same two policy guidelines. (A sole community hospital is defined as a…

The distribution of life cycle stages of two deep-water pleuronectids, Dover sole ( Microstomus pacificus) and rex sole ( Glyptocephalus zachirus), at the northern extent of their range in the Gulf of Alaska

NASA Astrophysics Data System (ADS)

Abookire, Alisa A.; Bailey, Kevin M.

2007-02-01

Dover sole ( Microstomus pacificus) and rex sole ( Glyptocephalus zachirus) are both commercially valuable, long-lived pleuronectids that are distributed widely throughout the North Pacific. While their ecology and life cycle have been described for southern stocks, few investigations have focused on these species at higher latitudes. We synthesized historical research survey data among critical developmental stages to determine the distribution of life cycle stages for both species in the northern Gulf of Alaska (GOA). Bottom trawl survey data from 1953 to 2004 (25 519 trawls) were used to characterize adult distribution during the non-spawning and spawning seasons, ichthyoplankton data from 1972 to 2003 (10 776 tows) were used to determine the spatial and vertical distribution of eggs and larvae, and small-meshed shrimp trawl survey data from 1972 to 2004 (6536 trawls) were used to characterize areas utilized by immature stages. During the non-spawning season, adult Dover sole and rex sole were widely distributed from the inner shelf to outer slope. While both species concentrated on the continental slope to spawn, Dover sole spawning areas were more geographically specific than rex sole. Although spawned in deep water, eggs of both species were found in surface waters near spawning areas. Dover sole larvae did not appear to have an organized migration from offshore spawning grounds toward coastal nursery areas, and our data indicated facultative settling to their juvenile habitat in winter. Rex sole larvae progressively moved cross-shelf toward shore as they grew from April to September, and larvae presumably settled in coastal nursery areas in the autumn. In contrast with studies in the southern end of their range, we found no evidence in the GOA that Dover or rex sole have pelagic larval stages longer than nine months; however, more sampling for large larvae is needed in winter offshore of the continental shelf as well as sampling for newly settled larvae over the shelf to verify an abbreviated pelagic larval stage for both species at the northern end of their range.

77 FR 45479 - Extension of Import Restrictions on Archaeological Objects and Ecclesiastical and Ritual...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-01

... restrictions has been revised. The Designated List and the regulatory text in that document contain language which is inadvertently not consistent with the rest of the document as to the historical period that the...

Transportation management center data capture for performance and mobility measures reference manual.

DOT National Transportation Integrated Search

2013-03-01

The Guide to Transportation Management Center (TMC) Data Capture for Performance and Mobility Measures is a two-volume document consisting of a summary Guidebook and this Reference Manual. These documents provide technical guidance and recommended pr...

Specification of the Transmitted Signal of the U.S. Marine Radiobeacon System

DOT National Transportation Integrated Search

1983-01-01

This report documents the specification of the transmitted signal of the U.S. Marine Radiobeacon System. It is intended as a reference document consisting of specifications, definitions, and explanations for general use by designers, manufacturers, a...

45 CFR 501.6 - Documentary evidence.

Code of Federal Regulations, 2010 CFR

2010-10-01

... UNITED STATES, DEPARTMENT OF JUSTICE RULES OF PRACTICE SUBPOENAS, DEPOSITIONS, AND OATHS § 501.6 Documentary evidence. Documentary evidence may consist of books, records, correspondence or other documents... application for the issuance of subpoenas for production of documents must specify the books, records...

Diversity in the later Paleogene proboscidean radiation: a small barytheriid from the Oligocene of Dhofar Governorate, Sultanate of Oman

NASA Astrophysics Data System (ADS)

Seiffert, Erik R.; Nasir, Sobhi; Al-Harthy, Abdulrahman; Groenke, Joseph R.; Kraatz, Brian P.; Stevens, Nancy J.; Al-Sayigh, Abdul Razak

2012-02-01

Despite significant recent improvements to our understanding of the early evolution of the Order Proboscidea (elephants and their extinct relatives), geographic sampling of the group's Paleogene fossil record remains strongly biased, with the first ~30 million years of proboscidean evolution documented solely in near-coastal deposits of northern Africa. The considerable morphological disparity that is observable among the late Eocene and early Oligocene proboscideans of northern Africa suggests that other, as yet unsampled, parts of Afro-Arabia might have served as important centers for the early diversification of major proboscidean clades. Here we describe the oldest taxonomically diagnostic remains of a fossil proboscidean from the Arabian Peninsula, a partial mandible of Omanitherium dhofarensis (new genus and species), from near the base of the early Oligocene Shizar Member of the Ashawq Formation, in the Dhofar Governorate of the Sultanate of Oman. The molars and premolars of Omanitherium are morphologically intermediate between those of Arcanotherium and Barytherium from northern Africa, but its specialized lower incisors are unlike those of other known Paleogene proboscideans in being greatly enlarged, high-crowned, conical, and tusk-like. Omanitherium is consistently placed close to late Eocene Barytherium in our phylogenetic analyses, and we place the new genus in the Family Barytheriidae. Some features of Omanitherium, such as tusk-like lower second incisors, the possible loss of the lower central incisors, an enlarged anterior mental foramen, and inferred elongate mandibular symphysis and diminutive P2, suggest a possible phylogenetic link with Deinotheriidae, an extinct family of proboscideans whose origins have long been mysterious.

Pneumocystis jirovecii pneumonia in systemic lupus erythematosus from southern Taiwan.

PubMed

Weng, Chia-Tse; Liu, Ming-Fei; Weng, Meng-Yu; Lee, Nan-Yao; Wang, Ming-Chang; Lin, Wei-Chieh; Ou, Chih-Ying; Lai, Wu-Wei; Hsu, Shiang-Chin; Chao, Sheau-Chiou; Chung, Ta-Jung; Lee, Chung-Ta; Shieh, Chi-Chang; Wang, Jiu-Yao; Wang, Chrong-Reen

2013-08-01

Opportunistic infection has been documented in systemic lupus erythematosus with special attention paid to Pneumocystis jirovecii because of the significant morbidity and high mortality. The limited large-scale investigations covering P. jirovecii pneumonia (PCP) in systemic lupus erythematosus following biologics or immunosuppressants therapy prompted us to perform this study in southern Taiwan. A retrospective study was completed in 858 hospitalized lupus patients from January 2000 to December 2011. The definite diagnosis of PCP was made by the laboratory detection of Pneumocystis organisms together with consistent clinical and radiological manifestations of PCP. Positive polymerase chain reaction results of sputum samples were not regarded as infection in this study, unless P. jirovecii was the sole pathogen found and pulmonary manifestations resolved following antibiotics for PCP treatment alone. The laboratory identification of Pneumocystis organisms depended on lung biopsy in 2 cases and bronchoalveolar lavage in 3 patients. Five cases, 2 women and 3 men aged 30 to 50 years (41.8 ± 8.8 years), were identified with a 0.6% incidence. None received chemoprophylactics against P. jirovecii infection. All had lupus nephritis and lymphopenia with low CD4 T-cell counts. Prior usages of higher daily prednisolone dosages and concomitant biologics or immunosuppressants were observed in all patients. Pneumocystis jirovecii pneumonia contributed to a high mortality rate (60%). We report the rare occurrence but high mortality of PCP infection in this study. A consensus guideline addressing prophylactic antibiotics against Pneumocystis organisms in highest-risk lupus patients on biologics or immunosuppressants could be helpful in guiding their management.

21 CFR 558.62 - Arsanilic acid.

Code of Federal Regulations, 2011 CFR

2011-04-01

... efficiency; improving pigmentation Withdraw 5 days before slaughter; as sole source of organic arsenic 015565... pigmentation. As erythromycin thiocyanate; withdraw 5 days before slaughter; as sole source of organic arsenic... pigmentation As erythromycin thiocyanate; withdraw 5 days before slaughter; as sole source of organic arsenic...

Micro Electro-Mechanical System (MEMS) Pressure Sensor for Footwear

DOEpatents

Kholwadwala, Deepesh K.; Rohrer, Brandon R.; Spletzer, Barry L.; Galambos, Paul C.; Wheeler, Jason W.; Hobart, Clinton G.; Givler, Richard C.

2008-09-23

Footwear comprises a sole and a plurality of sealed cavities contained within the sole. The sealed cavities can be incorporated as deformable containers within an elastic medium, comprising the sole. A plurality of micro electro-mechanical system (MEMS) pressure sensors are respectively contained within the sealed cavity plurality, and can be adapted to measure static and dynamic pressure within each of the sealed cavities. The pressure measurements can provide information relating to the contact pressure distribution between the sole of the footwear and the wearer's environment.

Habitat Suitability Index Models: Juvenile English sole

USGS Publications Warehouse

Toole, Christopher L.; Barnhart, Roger A.; Onuf, Christopher P.

1987-01-01

English sole (Parophrys vetulus) is one of the major commercial groundfish species caught along the Pacific coast. Landings in the United States and Canada averaged 4,947 t/yr between 1975 and 1984, placing it third in importance among flatfish caught by Pacific coast trawlers (Pacific Marine Fisheries Commission 1985). Juvenile English sole are also among the most abundant fishes in many bays and estuaries along the Pacific (Westrheim 1955; Sopher 1974; Ambrose 1976; Rogers 1985). The English sole is not an important recreational species.

/sup 32/P-postlabeling analysis of DNA adducts in liver of wild English sole (Parophrys vetulus) and winter flounder (Pseudopleuronectes americanus)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Varanasi, U.; Reichert, W.L.; Stein, J.E.

The 1-butanol adduct enhancement version of the 32P-postlabeling assay was used to measure the levels of hepatic DNA adducts in the marine flatfish, English sole (Parophrys vetulus), sampled from the Duwamish Waterway and Eagle Harbor, Puget Sound, WA, where they are exposed to high concentrations of sediment-associated chemical contaminants and exhibit an elevated prevalence of hepatic neoplasms. Hepatic DNA was also analyzed from English sole from a reference area (Useless Bay, WA) and from reference English sole treated with organic-solvent extracts of sediments from the two contaminated sites. Autoradiograms of thin-layer chromatograms of 32P-labeled hepatic DNA digests from English solemore » from the contaminated sites exhibited up to three diagonal radioactive zones, which were not present in autoradiograms of thin-layer chromatogram maps of 32P-labeled DNA digests from English sole from the reference site. These diagonal radioactive zones contained several distinct spots as well as what appeared to be multiple overlapping adduct spots. The levels (nmol of adducts/mol of nucleotides) of total DNA adducts for English sole from Duwamish Waterway and Eagle Harbor were 26 +/- 28 (DS) and 17 +/- 9.6, respectively. All autoradiograms of DNA from fish from the contaminated sites exhibited a diagonal radioactive zone where DNA adducts of chrysene, benzo(a)pyrene, and dibenz(a,h)anthracene, formed in vitro using English sole hepatic microsomes, were shown to chromatograph. English sole treated with extracts of the contaminated sediments had adduct profiles generally similar to those for English sole from the respective contaminated sites.« less

Structural evolution of the Semail Ophiolite metamorphic sole, Wadi Hawasina and Northern Jebel Nakhl Culmination, Oman

NASA Astrophysics Data System (ADS)

Hurtado, C.; Bailey, C.; Visokay, L.; Scharf, A.

2017-12-01

The Semail ophiolite is the world's largest and best-exposed ophiolite sequence, however the processes associated with both oceanic detachment and later emplacement onto the Arabian continental margin remain enigmatic. This study examines the upper mantle section of the ophiolite, its associated metamorphic sole, and the autochthonous strata beneath the ophiolite at two locations in northern Oman. Our purpose is to understand the structural history of ophiolite emplacement and evaluate the deformation kinematics of faulted and sheared rocks in the metamorphic sole. At Wadi Hawasina, the base of the ophiolite is defined by a 5- to 15-m thick zone of penetratively-serpentinized mylonitic peridotite. Kinematic indicators record top-to-the SW (reverse) sense-of-shear with a triclinic deformation asymmetry. An inverted metamorphic grade is preserved in the 300- to 500-m thick metamorphic sole that is thrust over deep-water sedimentary rocks of the Hawasina Group. The study site near Buwah, in the northern Jebel Nakhl culmination, contains a N-to-S progression of mantle peridotite, metamorphic sole, and underlying Jurassic carbonates. Liswanite crops out in NW-SE trending linear ridges in the peridotite. The metamorphic sole includes well-foliated quartzite, metachert, and amphibolite. Kinematic evidence indicates that the liswanite and a serpentinized mélange experienced top to-the north (normal) sense-of-shear. Two generations of E-W striking, N-dipping normal faults separate the autochthonous sequence from the metamorphic sole, and also cut out significant sections of the metamorphic sole. Fabric analysis reveals that the metamorphic sole experienced flattening strain (K<0.2) that accumulated during pure shear-dominated general shear (Wk<0.4). Normal faulting and extension at the Buwah site indicates that post-ophiolite deformation is significant in the Jebel Akhdar and Jebel Nakhl culminations.

Influence of economic and demographic factors on quality of life in renal transplant recipients.

PubMed

Chisholm, Marie A; Spivey, Christina A; Nus, Audrey Van

2007-01-01

The purpose of this study was to determine the influence of annual income, Medicare status, and demographic variables on the health-related quality of life (HQoL) of renal transplant recipients. A cross-sectional survey was mailed to 146 Georgia renal transplant recipients who had functional grafts. Data were collected using the SF-12 Health Survey (version 2), a demographics survey, and 2003 tax documents. One-way ANOVAs and Pearson's R correlations were used to examine relationships between annual income, Medicare status, demographic variables and SF-12 scores. Significant variables were included in stepwise multiple regression analyses. Data from 130 participants (89% response rate) were collected. Recipients with no Medicare coverage had significantly higher scores on the Physical Functioning and Role Physical SF-12 scales (p = 0.005) compared to recipients with Medicare. Annual income was positively correlated with General Health (p < 0.05). Age and race were significant predictors of Vitality (p = 0.004) and Physical Component Summary (p < 0.001) scores. Age, race, and Medicare status were significant predictors of Physical Functioning and Role Physical scores (p < 0.001). Age, annual income, race, and years post-transplant were significant predictors of General Health score (p < 0.001). Age was the sole predictor of Bodily Pain score (p = 0.002), and marital status was the sole predictor of Social Functioning score (p = 0.005). Interventions designed to offset financial barriers may be needed to bolster renal transplant recipients' HQoL.

Modeling fluvial incision and transient landscape evolution: Influence of dynamic channel adjustment

NASA Astrophysics Data System (ADS)

Attal, M.; Tucker, G. E.; Whittaker, A. C.; Cowie, P. A.; Roberts, G. P.

2008-09-01

Channel geometry exerts a fundamental control on fluvial processes. Recent work has shown that bedrock channel width depends on a number of parameters, including channel slope, and is not solely a function of drainage area as is commonly assumed. The present work represents the first attempt to investigate the consequences of dynamic, gradient-sensitive channel adjustment for drainage-basin evolution. We use the Channel-Hillslope Integrated Landscape Development (CHILD) model to analyze the response of a catchment to a given tectonic perturbation, using, as a template, the topography of a well-documented catchment in the footwall of an active normal fault in the Apennines (Italy) that is known to be undergoing a transient response to tectonic forcing. We show that the observed transient response can be reproduced to first order with a simple detachment-limited fluvial incision law. Transient landscape is characterized by gentler gradients and a shorter response time when dynamic channel adjustment is allowed. The differences in predicted channel geometry between the static case (width dependent solely on upstream area) and dynamic case (width dependent on both drainage area and channel slope) lead to contrasting landscape morphologies when integrated at the scale of a whole catchment, particularly in presence of strong tilting and/or pronounced slip-rate acceleration. Our results emphasize the importance of channel width in controlling fluvial processes and landscape evolution. They stress the need for using a dynamic hydraulic scaling law when modeling landscape evolution, particularly when the relative uplift field is nonuniform.

Patternmaker. Apprenticeship Training Standards.

ERIC Educational Resources Information Center

Ontario Ministry of Skills Development, Toronto.

This training document outlines the apprenticeship training standards for the trade of patternmaker that have been approved by the Ontario Ministry of Skills Development. The document consists of the following: (1) skills (competencies) identified by a trade analysis development group of practicing patternmakers; (2) general performance objectives…

A Model-Driven Visualization Tool for Use with Model-Based Systems Engineering Projects

NASA Technical Reports Server (NTRS)

Trase, Kathryn; Fink, Eric

2014-01-01

Model-Based Systems Engineering (MBSE) promotes increased consistency between a system's design and its design documentation through the use of an object-oriented system model. The creation of this system model facilitates data presentation by providing a mechanism from which information can be extracted by automated manipulation of model content. Existing MBSE tools enable model creation, but are often too complex for the unfamiliar model viewer to easily use. These tools do not yet provide many opportunities for easing into the development and use of a system model when system design documentation already exists. This study creates a Systems Modeling Language (SysML) Document Traceability Framework (SDTF) for integrating design documentation with a system model, and develops an Interactive Visualization Engine for SysML Tools (InVEST), that exports consistent, clear, and concise views of SysML model data. These exported views are each meaningful to a variety of project stakeholders with differing subjects of concern and depth of technical involvement. InVEST allows a model user to generate multiple views and reports from a MBSE model, including wiki pages and interactive visualizations of data. System data can also be filtered to present only the information relevant to the particular stakeholder, resulting in a view that is both consistent with the larger system model and other model views. Viewing the relationships between system artifacts and documentation, and filtering through data to see specialized views improves the value of the system as a whole, as data becomes information

A database for TMT interface control documents

NASA Astrophysics Data System (ADS)

Gillies, Kim; Roberts, Scott; Brighton, Allan; Rogers, John

2016-08-01

The TMT Software System consists of software components that interact with one another through a software infrastructure called TMT Common Software (CSW). CSW consists of software services and library code that is used by developers to create the subsystems and components that participate in the software system. CSW also defines the types of components that can be constructed and their roles. The use of common component types and shared middleware services allows standardized software interfaces for the components. A software system called the TMT Interface Database System was constructed to support the documentation of the interfaces for components based on CSW. The programmer describes a subsystem and each of its components using JSON-style text files. A command interface file describes each command a component can receive and any commands a component sends. The event interface files describe status, alarms, and events a component publishes and status and events subscribed to by a component. A web application was created to provide a user interface for the required features. Files are ingested into the software system's database. The user interface allows browsing subsystem interfaces, publishing versions of subsystem interfaces, and constructing and publishing interface control documents that consist of the intersection of two subsystem interfaces. All published subsystem interfaces and interface control documents are versioned for configuration control and follow the standard TMT change control processes. Subsystem interfaces and interface control documents can be visualized in the browser or exported as PDF files.

A general concept for consistent documentation of computational analyses

PubMed Central

Müller, Fabian; Nordström, Karl; Lengauer, Thomas; Schulz, Marcel H.

2015-01-01

The ever-growing amount of data in the field of life sciences demands standardized ways of high-throughput computational analysis. This standardization requires a thorough documentation of each step in the computational analysis to enable researchers to understand and reproduce the results. However, due to the heterogeneity in software setups and the high rate of change during tool development, reproducibility is hard to achieve. One reason is that there is no common agreement in the research community on how to document computational studies. In many cases, simple flat files or other unstructured text documents are provided by researchers as documentation, which are often missing software dependencies, versions and sufficient documentation to understand the workflow and parameter settings. As a solution we suggest a simple and modest approach for documenting and verifying computational analysis pipelines. We propose a two-part scheme that defines a computational analysis using a Process and an Analysis metadata document, which jointly describe all necessary details to reproduce the results. In this design we separate the metadata specifying the process from the metadata describing an actual analysis run, thereby reducing the effort of manual documentation to an absolute minimum. Our approach is independent of a specific software environment, results in human readable XML documents that can easily be shared with other researchers and allows an automated validation to ensure consistency of the metadata. Because our approach has been designed with little to no assumptions concerning the workflow of an analysis, we expect it to be applicable in a wide range of computational research fields. Database URL: http://deep.mpi-inf.mpg.de/DAC/cmds/pub/pyvalid.zip PMID:26055099

Habitat selection of juvenile sole (Solea solea L.): Consequences for shoreface nourishment

NASA Astrophysics Data System (ADS)

Post, Marjolein H. M.; Blom, Ewout; Chen, Chun; Bolle, Loes J.; Baptist, Martin J.

2017-04-01

The shallow coastal zone is an essential nursery habitat for juvenile flatfish species such as sole (Solea solea L.). The increased frequency of shoreface nourishments along the coast is likely to affect this nursery function by altering important habitat conditions, including sediment grain size. Sediment preference of juvenile sole (41-91 mm) was studied in a circular preference chamber in order to understand the relationship between grain size and sole distribution. The preference tests were carried out at 11 °C and 20 °C to reflect seasonal influences. The juveniles showed a significant preference for finer sediments. This preference was not length dependent (within the length range tested) nor affected by either temperatures. Juvenile sole have a small home range and are not expected to move in response to unfavourable conditions. As a result, habitat alterations may have consequences for juvenile survival and subsequently for recruitment to adult populations. It is therefore important to carefully consider nourishment grain size characteristics to safeguard suitable nursery habitats for juvenile sole.

Nuclear factor 45 of tongue sole (Cynoglossus semilaevis): evidence for functional differentiation between two isoforms in immune defense against viral and bacterial pathogens.

PubMed

Chi, Heng; Hu, Yong-hua; Xiao, Zhi-zhong; Sun, Li

2014-02-01

Nuclear factor 45 (NF45) is known to play an important role in regulating interleukin-2 expression in mammals. The function of fish NF45 is largely unknown. In a previous study, we reported the identification of a NF45 (named CsNF45) from half smooth tongue sole (Cynoglossus semilaevis). In the present study, we identified an isoform of CsNF45 (named CsNF45i) from half smooth tongue sole and examined its biological properties in comparison with CsNF45. We found that CsNF45i is a truncated version of CsNF45 and lacks the N-terminal 38 residues of CsNF45. Genetic analysis showed that the CsNF45 gene consists of 14 exons and 13 introns, and that CsNF45 and CsNF45i are the products of alternative splicing. Constitutive expression of CsNF45 and CsNF45i occurred in multiple tissues but differed in patterns. Experimental infection with viral and bacterial pathogens upregulated the expression of both isoforms but to different degrees, with potent induction of CsNF45 being induced by bacterial pathogen, while dramatic induction of CsNF45i being induced by viral pathogen. Transient transfection analysis showed that both isoforms were localized in the nucleus and able to stimulate the activity of IL-2 promoter to comparable extents. To examine their in vivo effects, the two isoforms were overexpressed in tongue sole. Subsequent analysis showed that following viral and bacterial infection, the viral loads in CsNF45i-overexpressing fish were significantly lower than those in CsNF45-overexpressing fish, whereas the bacterial loads in CsNF45-overexpressing fish were significantly lower than those in CsNF45i-overexpressing fish. These results indicate that both CsNF45 and CsNF45i possess immunoregulatory properties, however, the two isoforms most likely participate in different aspects of host immune defense that target different pathogens. Copyright © 2013 Elsevier Ltd. All rights reserved.

Improving automation standards via semantic modelling: Application to ISA88.

PubMed

Dombayci, Canan; Farreres, Javier; Rodríguez, Horacio; Espuña, Antonio; Graells, Moisès

2017-03-01

Standardization is essential for automation. Extensibility, scalability, and reusability are important features for automation software that rely in the efficient modelling of the addressed systems. The work presented here is from the ongoing development of a methodology for semi-automatic ontology construction methodology from technical documents. The main aim of this work is to systematically check the consistency of technical documents and support the improvement of technical document consistency. The formalization of conceptual models and the subsequent writing of technical standards are simultaneously analyzed, and guidelines proposed for application to future technical standards. Three paradigms are discussed for the development of domain ontologies from technical documents, starting from the current state of the art, continuing with the intermediate method presented and used in this paper, and ending with the suggested paradigm for the future. The ISA88 Standard is taken as a representative case study. Linguistic techniques from the semi-automatic ontology construction methodology is applied to the ISA88 Standard and different modelling and standardization aspects that are worth sharing with the automation community is addressed. This study discusses different paradigms for developing and sharing conceptual models for the subsequent development of automation software, along with presenting the systematic consistency checking method. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Comments from the Developmental Neurotoxicology Committee of the Japanese Teratology Society on the OECD Guideline for the Testing of Chemicals, Proposal for a New Guideline 426, Developmental Neurotoxicity Study, Draft Document (October 2006 version), and on the Draft Document of the Retrospective Performance Assessment of the Draft Test Guideline 426 on Developmental Neurotoxicity.

PubMed

Ema, Makoto; Fukui, Yoshihiro; Aoyama, Hiroaki; Fujiwara, Michio; Fuji, Junichiro; Inouye, Minoru; Iwase, Takayuki; Kihara, Takahide; Oi, Akihide; Otani, Hiroki; Shinomiya, Mitsuhiro; Sugioka, Kozo; Yamano, Tsunekazu; Yamashita, Keisuke H; Tanimura, Takashi

2007-06-01

In October 2006, a new revision of the draft guideline (OECD Guideline for the Testing of Chemicals, Proposal for a New Guideline 426. Developmental Neurotoxicity Study) and Draft Document of the Retrospective Performance Assessment (RPA) of the Draft Test Guideline 426 on Developmental Neurotoxicity were distributed following incorporation of the results of the Expert Consultation Meeting in Tokyo on May 24-26, 2005. The draft guideline consists of 50 paragraphs and an appendix with 102 references; and the draft RPA consists of 37 paragraphs with 109 references. National coordinators were requested to arrange for national expert reviews of these draft documents in their member countries. Members of the Developmental Neurotoxicology (DNT) Committee of the Japanese Teratology Society (JTS) reviewed, discussed, and commented on the draft Test Guideline Proposal. The DNT Committee of the JTS also commented on the draft document of the RPA. These comments were sent to the OECD Secretariat. The DNT Committee of the JTS expects the comments to be useful for the finalization of these draft documents.

Sole Source Aquifers for NY and NJ

EPA Pesticide Factsheets

This layer is the designated sole source aquifers of New York and New Jersey. A Sole Source Aquifer, is an aquifer that supplies 50% or more of the drinking water for a given area where there are no reasonably available alternative sources should the aquifer become contaminated.

21 CFR 520.2088 - Roxarsone tablets.

Code of Federal Regulations, 2011 CFR

2011-04-01

... period. Withdraw 5 days before slaughter. Use as sole source of organic arsenic. (ii) Growing chickens—(a.... Withdraw 5 days before slaughter. Use as sole source of organic arsenic. (b)(1) Specifications. Each tablet... slaughter. Use as sole source of organic arsenic. (ii) [Reserved] (c)(1) Specifications. Each tablet...

Kinetic Assessment of Golf Shoe Outer Sole Design Features

PubMed Central

Smith, Neal A.; Dyson, Rosemary J.

2009-01-01

This study assessed human kinetics in relation to golf shoe outer sole design features during the golf swing using a driver club by measuring both within the shoe, and beneath the shoe at the natural grass interface. Three different shoes were assessed: metal 7- spike shoe, alternative 7-spike shoe, and a flat soled shoe. In-shoe plantar pressure data were recorded using Footscan RS International pressure insoles and sampling at 500 Hz. Simultaneously ground reaction force at the shoe outer sole was measured using 2 natural grass covered Kistler force platforms and 1000 Hz data acquisition. Video recording of the 18 right-handed golfers at 200 Hz was undertaken while the golfer performed 5 golf shots with his own driver in each type of shoe. Front foot (nearest to shot direction) maximum vertical force and torque were greater than at the back foot, and there was no significant difference related to the shoe type. Wearing the metal spike shoe when using a driver was associated with more torque generation at the back foot (p < 0. 05) than when the flat soled shoe was worn. Within shoe regional pressures differed significantly with golf shoe outer sole design features (p < 0.05). Comparison of the metal spike and alternative spike shoe results provided indications of the quality of regional traction on the outer sole. Potential golf shoe outer sole design features and traction were presented in relation to phases of the golf swing movement. Application of two kinetic measurement methods identified that moderated (adapted) muscular control of foot and body movement may be induced by golf shoe outer sole design features. Ground reaction force measures inform comparisons of overall shoe functional performance, and insole pressure measurements inform comparisons of the underfoot conditions induced by specific regions of the golf shoe outer sole. Key points Assessments of within golf shoe pressures and beneath shoe forces at the natural grass interface were conducted during golf shots with a driver. Application of two kinetic measurement methods simultaneously identified that moderated (adapted) muscular control of the foot and body movement may be induced by golf shoe outer sole localised design features. Ground force measures inform overall shoe kinetic functional performance. Insole pressure measurement informs of underfoot conditions induced by localised specific regions of the golf outer sole. Significant differences in ground-shoe torque generation and insole regional pressures were identified when different golf shoes were worn. PMID:24149603

Tank waste remediation system functions and requirements document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carpenter, K.E

1996-10-03

This is the Tank Waste Remediation System (TWRS) Functions and Requirements Document derived from the TWRS Technical Baseline. The document consists of several text sections that provide the purpose, scope, background information, and an explanation of how this document assists the application of Systems Engineering to the TWRS. The primary functions identified in the TWRS Functions and Requirements Document are identified in Figure 4.1 (Section 4.0) Currently, this document is part of the overall effort to develop the TWRS Functional Requirements Baseline, and contains the functions and requirements needed to properly define the top three TWRS function levels. TWRS Technicalmore » Baseline information (RDD-100 database) included in the appendices of the attached document contain the TWRS functions, requirements, and architecture necessary to define the TWRS Functional Requirements Baseline. Document organization and user directions are provided in the introductory text. This document will continue to be modified during the TWRS life-cycle.« less

Increasing Sales by Developing Production Consortiums.

ERIC Educational Resources Information Center

Smith, Christopher A.; Russo, Robert

Intended to help rehabilitation facility administrators increase organizational income from manufacturing and/or contracted service sources, this document provides a decision-making model for the development of a production consortium. The document consists of five chapters and two appendices. Chapter 1 defines the consortium concept, explains…

Motivation through Routine Documentation

ERIC Educational Resources Information Center

Koth, Laurie J.

2016-01-01

This informed commentary article offers a simple, effective classroom management strategy in which the teacher uses routine documentation to motivate students both to perform academically and to behave in a manner consistent with established classroom rules and procedures. The pragmatic strategy is grounded in literature, free to implement,…

Autobody Technology Curriculum Guide.

ERIC Educational Resources Information Center

Idaho State Dept. of Education, Boise. Div. of Vocational Education.

This Idaho state curriculum guide provides lists of tasks, performance objectives, and enabling objectives for instruction in auto body technology. Following a curriculum framework that explains major content, laboratory activities, and intended outcomes, the document lists all tasks covered in the curriculum. The bulk of the document consists of…

Mobile hybrid LiDAR & infrared sensing for natural gas pipeline monitoring compendium.

DOT National Transportation Integrated Search

2016-01-01

This item consists of several documents that were created throughout the Mobile Hybrid LiDAR & Infrared Sensing for Natural Gas Pipeline Monitoring project, No. RITARS-14-H-RUT, which was conducted from January 15, 2014 to June 30, 2016. Documents in...

[Computer eyeglasses--aspects of a confusing topic].

PubMed

Huber-Spitzy, V; Janeba, E

1997-01-01

With the coming into force of the new Austrian Employee Protection Act the issue of the so called "computer glasses" will also gain added importance in our country. Such glasses have been defined as vision aids to be exclusively used for the work on computer monitors and include single-vision glasses solely intended for reading computer screen, glasses with bifocal lenses for reading computer screen and hard-copy documents as well as those with varifocal lenses featuring a thickened central section. There is still a considerable controversy among those concerned as to who will bear the costs for such glasses--most likely it will be the employer. Prescription of such vision aids will be exclusively restricted to ophthalmologists, based on a thorough ophthalmological examination under adequate consideration of the specific working environment and the workplace requirements of the individual employee concerned.

Design and application of electromechanical actuators for deep space missions

NASA Technical Reports Server (NTRS)

Haskew, Tim A.; Wander, John

1994-01-01

This progress report documents research and development efforts performed from August 16, 1993 through August 15, 1994 on NASA Grant NAG8-240, 'Design and Application of Electromechanical Actuators for Deep Space Missions.' Since the submission of our last progress report in February 1994, our efforts have been almost entirely focused on final construction of the test stand and experiment design. Hence, this report is dedicated solely to these topics. However, updates on our research personnel and our health monitoring and fault management efforts are provided in this summary. Following this executive summary are two report sections. The first is devoted to the motor drive being constructed for the test stand. The thrust of the next section is the mechanical and hydraulic design and construction based on the planned experimental requirements. Following both major sections are three appendices.

75 FR 16202 - Office of New Reactors; Interim Staff Guidance on Ensuring Hazard-Consistent Seismic Input for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

... Staff Guidance on Ensuring Hazard-Consistent Seismic Input for Site Response and Soil Structure...-Consistent Seismic Input for Site Response and Soil Structure Interaction Analyses,'' (Agencywide Documents... Soil Structure Interaction Analyses,'' (ADAMS Accession No. ML092230455) to solicit public and industry...

31 CFR 543.301 - Arms or any related materiel.

Code of Federal Regulations, 2010 CFR

2010-07-01

... solely for humanitarian or protective use, and related technical assistance and training; (c) Supplies of... of arms and related materiel and technical training and assistance intended solely for support of or... technical assistance intended solely for the support of or use by the United Nations Operation in Côte d...

75 FR 38687 - Federal Acquisition Regulation; FAR Case 2008-023, Clarification of Criteria for Sole Source...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-02

... a sole source SDVOSB concern acquisition. The final rule contains language that more closely mirrors...-AL29 Federal Acquisition Regulation; FAR Case 2008-023, Clarification of Criteria for Sole Source...: Final rule. SUMMARY: The Civilian Agency Acquisition Council and the Defense Acquisition Regulations...

31 CFR 515.546 - Accounts of Cuban sole proprietorships.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Accounts of Cuban sole proprietorships. 515.546 Section 515.546 Money and Finance: Treasury Regulations Relating to Money and Finance... proprietorships. Specific licenses are issued unblocking sole proprietorships established under the laws of Cuba...

31 CFR 515.546 - Accounts of Cuban sole proprietorships.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Accounts of Cuban sole proprietorships. 515.546 Section 515.546 Money and Finance: Treasury Regulations Relating to Money and Finance... proprietorships. Specific licenses are issued unblocking sole proprietorships established under the laws of Cuba...

31 CFR 515.546 - Accounts of Cuban sole proprietorships.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Accounts of Cuban sole proprietorships. 515.546 Section 515.546 Money and Finance: Treasury Regulations Relating to Money and Finance... proprietorships. Specific licenses are issued unblocking sole proprietorships established under the laws of Cuba...

31 CFR 515.546 - Accounts of Cuban sole proprietorships.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Accounts of Cuban sole proprietorships. 515.546 Section 515.546 Money and Finance: Treasury Regulations Relating to Money and Finance... proprietorships. Specific licenses are issued unblocking sole proprietorships established under the laws of Cuba...

31 CFR 800.223 - Solely for the purpose of passive investment.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (Continued) OFFICE OF INVESTMENT SECURITY, DEPARTMENT OF THE TREASURY REGULATIONS PERTAINING TO MERGERS, ACQUISITIONS, AND TAKEOVERS BY FOREIGN PERSONS Definitions § 800.223 Solely for the purpose of passive... Board of Directors. The acquisition by Corporation A of a voting interest in Corporation B is not solely...

Performatively Queer: Sole Parent Postgraduates in the Australian Academy

ERIC Educational Resources Information Center

Hook, Genine A.

2015-01-01

This paper draws on research that considers how gender and agency influence the engagement of sole parent postgraduates within the Australian academy. I argue that parental care responsibilities critically influence participation in higher education for sole parents. I suggest that the gendered construct of caring for children is a feminine…

78 FR 51061 - TRICARE; Reimbursement of Sole Community Hospitals and Adjustment to Reimbursement of Critical...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-20

... DEPARTMENT OF DEFENSE 32 CFR Part 199 [DoD-2010-HA-0072] RIN 0720-AB41 TRICARE; Reimbursement of Sole Community Hospitals and Adjustment to Reimbursement of Critical Access Hospitals; Correction... TRICARE; Reimbursement of Sole Community Hospitals and Adjustment to Reimbursement of Critical Access...

Puget Sound Dredged Disposal Analysis (PSDDA). Final Environmental Impact Statement Unconfined Open-Water Disposal for Dredged Material, Phase 2. (North and South Puget Sound)

DTIC Science & Technology

1989-09-01

flathead sole, rex sole, and rock sole all showed indications of blood worm infestations. One liver tumor was found in a rex sole during spring in the ZSF...concentrations Hainly in invertebrates; some trations (.01 ppb) in waters (from lOx to 42Ox reference) in fish livers ; rarely in fish of Puget Sound central...Eagle Harbor, and Sinclair fish livers , and birds in Inlet. Highest elevation industrialized ’-ban areas. along Ruston-Point Defiance Copper is a natural

Personal equipment for low seam coal miners. 8. Improved traction rubber boot soles. Report for 1978-82

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanders, M.S.; Downing, J.V.

1982-10-01

Based on laboratory and preliminary field tests of off-the-shelf steel-toed rubber boots, a molded sole design was developed to provide increased traction over conventional calendared sole miners boots. The pattern provided sharp edges perpendicular to both lateral and fore-aft slip vectors. The sole was designed to reduce mud caking. An instep lace-up capability was added to better secure the foot inside the boot. A 5-month field evaluation compared the prototype boots to the boots the participants usually wear.

Model-based document categorization employing semantic pattern analysis and local structure clustering

NASA Astrophysics Data System (ADS)

Fume, Kosei; Ishitani, Yasuto

2008-01-01

We propose a document categorization method based on a document model that can be defined externally for each task and that categorizes Web content or business documents into a target category in accordance with the similarity of the model. The main feature of the proposed method consists of two aspects of semantics extraction from an input document. The semantics of terms are extracted by the semantic pattern analysis and implicit meanings of document substructure are specified by a bottom-up text clustering technique focusing on the similarity of text line attributes. We have constructed a system based on the proposed method for trial purposes. The experimental results show that the system achieves more than 80% classification accuracy in categorizing Web content and business documents into 15 or 70 categories.

The detailed measurement of foot clearance by young adults during stair descent.

PubMed

Telonio, A; Blanchet, S; Maganaris, C N; Baltzopoulos, V; McFadyen, B J

2013-04-26

Foot clearance is an important variable for understanding safe stair negotiation, but few studies have provided detailed measures of it. This paper presents a new method to calculate minimal shoe clearance during stair descent and compares it to previous literature. Seventeen healthy young subjects descended a five step staircase with step treads of 300 mm and step heights of 188 mm. Kinematic data were collected with an Optotrak system (model 3020) and three non-colinear infrared markers on the feet. Ninety points were digitized on the foot sole prior to data collection using a 6 marker probe and related to the triad of markers on the foot. The foot sole was reconstructed using the Matlab (version 7.0) "meshgrid" function and minimal distance to each step edge was calculated for the heel, toe and foot sole. Results showed significant differences in minimum clearance between sole, heel and toe, with the shoe sole being the closest and the toe the furthest. While the hind foot sole was closest for 69% of the time, the actual minimum clearance point on the sole did vary across subjects and staircase steps. This new method, and the findings on healthy young subjects, can be applied to future studies of other populations and staircase dimensions. Copyright © 2013 Elsevier Ltd. All rights reserved.

75 FR 67809 - Magnuson-Stevens Act Provisions; Fisheries Off West Coast States; Pacific Coast Groundfish...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-03

...This proposed action would establish the 2011-2012 harvest specifications and management measures for groundfish taken in the U.S. exclusive economic zone (EEZ) off the coasts of Washington, Oregon, and California consistent with the Magnuson-Stevens Fishery Conservation and Management Act and the Pacific Coast Groundfish Fishery Management Plan (PCGFMP). This action revises the collection of management measures in the groundfish fishery regulations that are intended to keep the total catch of each groundfish species or species complex within the harvest specifications. This action also includes regulations to implement Amendments 16-5 and 23 to the PCGFMP. Amendment 16-5 would revise existing rebuilding plans, create a new rebuilding plan for Petrale sole, which was declared overfished on February 9, 2010, and revise status determination criteria and a harvest control rule for flatfish. This action is consistent with and partially implements Amendment 23 to the PCGFMP. Amendment 23 would make the PCGFMP consistent with the revised National Standard 1 Guidelines (74 FR 3178, January 16, 2009).

Adult Education at a Distance.

ERIC Educational Resources Information Center

Gaudet, Alphonse

This document, which examines the use of educational technologies for distance education for adults in Canada, consists of five narrative sections and a bibliography. The first section introduces the topic and the document's objectives (to describe those technologies used in Canadian adult distance education, paying particular attention to those…

18 CFR 5.25 - Applications requiring a draft NEPA document.

Code of Federal Regulations, 2010 CFR

2010-04-01

... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... include for comment draft license articles, a preliminary determination of the consistency of each fish...

18 CFR 5.25 - Applications requiring a draft NEPA document.

Code of Federal Regulations, 2011 CFR

2011-04-01

... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... include for comment draft license articles, a preliminary determination of the consistency of each fish...

3 CFR - Continuation of Emergency Regarding Export Control Regulations

Code of Federal Regulations, 2012 CFR

2012-01-01

... 3 The President 1 2012-01-01 2012-01-01 false Continuation of Emergency Regarding Export Control Regulations Presidential Documents Other Presidential Documents Notice of August 12, 2011 Continuation of Emergency Regarding Export Control Regulations On August 17, 2001, consistent with the authority provided to...

77 FR 26061 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Order Granting Approval of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-02

...-Regulatory Organizations; Municipal Securities Rulemaking Board; Order Granting Approval of Proposed Rule Change Consisting of Establishment of a Subscription to Historical Information and Documents Submitted to... historical information and documents submitted to the MSRB's Short-Term Obligation Rate Transparency System...

3 CFR - Unified Command Plan 2011

Code of Federal Regulations, 2012 CFR

2012-01-01

... 3 The President 1 2012-01-01 2012-01-01 false Unified Command Plan 2011 Presidential Documents Other Presidential Documents Memorandum of April 6, 2011 Unified Command Plan 2011 Memorandum for the... implementation of the revised Unified Command Plan. Consistent with title 10, United States Code, section 161(b...

How to Link to Official Documents from the Government Publishing Office (GPO)

EPA Pesticide Factsheets

The most consistent way to present up-to-date content from the Federal Register, US Code, Code of Federal Regulations (CFR), and so on is to link to the official version of the document on the GPO's Federal Digital System (FDSys) website.

77 FR 72829 - Marine Mammals; File No. 16305

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... Toxicology, Maine Center for Toxicology and Environmental Health, University of Southern Maine, 478 Science... turtle biological samples for scientific research purposes. ADDRESSES: The permit and related documents... consistent with the purposes and policies set forth in section 2 of the ESA. Documents may be reviewed in the...

14 CFR 302.4 - General requirements as to documents.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., along with the telephone and facsimile numbers and, if available, electronic mail address of that person... website. (3) All documents filed under this part consisting of twenty (20) or more pages must contain a... subscription requirements shall be those specified at the DOT DMS internet website. ...

14 CFR 302.4 - General requirements as to documents.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., along with the telephone and facsimile numbers and, if available, electronic mail address of that person... website. (3) All documents filed under this part consisting of twenty (20) or more pages must contain a... subscription requirements shall be those specified at the DOT DMS internet website. ...

14 CFR 302.4 - General requirements as to documents.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., along with the telephone and facsimile numbers and, if available, electronic mail address of that person... website. (3) All documents filed under this part consisting of twenty (20) or more pages must contain a... subscription requirements shall be those specified at the DOT DMS internet website. ...

Computer-assisted coding and clinical documentation: first things first.

PubMed

Tully, Melinda; Carmichael, Angela

2012-10-01

Computer-assisted coding tools have the potential to drive improvements in seven areas: Transparency of coding. Productivity (generally by 20 to 25 percent for inpatient claims). Accuracy (by improving specificity of documentation). Cost containment (by reducing overtime expenses, audit fees, and denials). Compliance. Efficiency. Consistency.

Center for Employment Training Annual Report. 1989.

ERIC Educational Resources Information Center

Center for Employment Training, San Jose, CA.

This document summarizes the 1989 performance of the Center for Employment Training (CET) a nonprofit corporation with training centers located throughout the West. The document consists of a variety of reports and "focus" pieces examining labor market changes and CET's adjustments in its operations. The executive director's report…

Spatial and ontogenetic variability in the chemical composition of juvenile common sole ( Solea solea) otoliths

NASA Astrophysics Data System (ADS)

Tanner, S. E.; Vasconcelos, R. P.; Reis-Santos, P.; Cabral, H. N.; Thorrold, S. R.

2011-01-01

A description of variations in the chemical composition of fish otoliths at different spatial scales and life history stages is a prerequisite for their use as natural tags in fish population connectivity and migration studies. Otolith geochemistry of juvenile common sole ( Solea solea), a marine migrant species collected in six Portuguese estuaries was examined. Elemental ratios (Mg:Ca, Mn:Ca, Cu:Ca, Sr:Ca, Ba:Ca, Pb:Ca) were analysed in two zones of the right otolith (corresponding to late larval and juvenile stages) using laser ablation inductively coupled plasma mass spectrometry (ICP-MS). Stable carbon and oxygen isotopes (δ 13C and δ 18O) were determined in left otoliths using isotopic ratio monitoring mass spectrometry (irm-MS). Significant differences in otolith geochemical signatures were found among estuaries, among sites within estuaries and between otolith zones. Several elemental ratios (Mg:Ca, Mn:Ca, Cu:Ca and Sr:Ca) showed consistent patterns between otolith zones and were likely influenced by environmental factors and ontogenetic effects associated with physiological changes during metamorphosis. Assignment of individuals to their collection estuary based on the otolith geochemical signatures was more accurate at the site level (81%) than among estuaries (69%). Site temperature was not correlated with any of the elemental or isotope ratios, but salinity was significantly correlated with Ba:Ca, δ 13C and δ 18O. Observed spatial variations among estuaries and sites within estuaries indicate that geochemical signatures in otoliths are accurate natural tags of estuarine habitat in common sole. Nevertheless, the significant variations observed between otolith zones should be taken into account in the design of population connectivity studies.

Identification, characterization and functional analysis of regulatory region of nanos gene from half-smooth tongue sole (Cynoglossus semilaevis).

PubMed

Huang, Jinqiang; Li, Yongjuan; Shao, Changwei; Wang, Na; Chen, Songlin

2017-06-20

The nanos gene encodes an RNA-binding zinc finger protein, which is required in the development and maintenance of germ cells. However, there is very limited information about nanos in flatfish, which impedes its application in fish breeding. In this study, we report the molecular cloning, characterization and functional analysis of the 3'-untranslated region of the nanos gene (Csnanos) from half-smooth tongue sole (Cynoglossus semilaevis), which is an economically important flatfish in China. The 1233-bp cDNA sequence, 1709-bp genomic sequence and flanking sequences (2.8-kb 5'- and 1.6-kb 3'-flanking regions) of Csnanos were cloned and characterized. Sequence analysis revealed that CsNanos shares low homology with Nanos in other species, but the zinc finger domain of CsNanos is highly similar. Phylogenetic analysis indicated that CsNanos belongs to the Nanos2 subfamily. Csnanos expression was widely detected in various tissues, but the expression level was higher in testis and ovary. During early development and sex differentiation, Csnanos expression exhibited a clear sexually dimorphic pattern, suggesting its different roles in the migration and differentiation of primordial germ cells (PGCs). Higher expression levels of Csnanos mRNA in normal females and males than in neomales indicated that the nanos gene may play key roles in maintaining the differentiation of gonad. Moreover, medaka PGCs were successfully labeled by the microinjection of synthesized mRNA consisting of green fluorescence protein and the 3'-untranslated region of Csnanos. These findings provide new insights into nanos gene expression and function, and lay the foundation for further study of PGC development and applications in tongue sole breeding. Copyright © 2017 Elsevier B.V. All rights reserved.

The great melting pot. Common sole population connectivity assessed by otolith and water fingerprints.

PubMed

Morat, Fabien; Letourneur, Yves; Dierking, Jan; Pécheyran, Christophe; Bareille, Gilles; Blamart, Dominique; Harmelin-Vivien, Mireille

2014-01-01

Quantifying the scale and importance of individual dispersion between populations and life stages is a key challenge in marine ecology. The common sole (Solea solea), an important commercial flatfish in the North Sea, Atlantic Ocean and the Mediterranean Sea, has a marine pelagic larval stage, a benthic juvenile stage in coastal nurseries (lagoons, estuaries or shallow marine areas) and a benthic adult stage in deeper marine waters on the continental shelf. To date, the ecological connectivity among these life stages has been little assessed in the Mediterranean. Here, such an assessment is provided for the first time for the Gulf of Lions, NW Mediterranean, based on a dataset on otolith microchemistry and stable isotopic composition as indicators of the water masses inhabited by individual fish. Specifically, otolith Ba/Ca and Sr/Ca profiles, and δ(13)C and δ(18)O values of adults collected in four areas of the Gulf of Lions were compared with those of young-of-the-year collected in different coastal nurseries. Results showed that a high proportion of adults (>46%) were influenced by river inputs during their larval stage. Furthermore Sr/Ca ratios and the otolith length at one year of age revealed that most adults (∼70%) spent their juvenile stage in nurseries with high salinity, whereas the remainder used brackish environments. In total, data were consistent with the use of six nursery types, three with high salinity (marine areas and two types of highly saline lagoons) and three brackish (coastal areas near river mouths, and two types of brackish environments), all of which contributed to the replenishment of adult populations. These finding implicated panmixia in sole population in the Gulf of Lions and claimed for a habitat integrated management of fisheries.

Evaluation of combined prescription of rocker sole shoes and custom-made foot orthoses for the treatment of plantar fasciitis.

PubMed

Fong, Daniel Tik-Pui; Pang, Kai-Yip; Chung, Mandy Man-Ling; Hung, Aaron See-Long; Chan, Kai-Ming

2012-12-01

It is a routine practice to prescribe a combination of rocker shoes and custom-made foot orthoses for patients with plantar fasciitis. Recently, there has been a debate on this practice, and studies have shown that the individual prescription of rocker shoes or custom-made foot orthoses is effective in treating plantar fasciitis. The aim of this study was to evaluate and compare the immediate therapeutic effects of individually prescribed rocker sole shoes and custom-made foot orthoses, and a combined prescription of them on plantar fasciitis. This was a cross-over study. Fifteen patients with unilateral plantar fasciitis were recruited; they were from both genders and aged between 40 and 65. Subjects performed walking trials which consisted of one 'unshod' condition and four 'shod' conditions while wearing baseline shoes, rocker shoes, baseline shoes with foot orthotics, and rocker shoes with foot orthotics. The study outcome measures were the immediate heel pain intensity levels as reflected by visual analog scale pain ratings and the corresponding dynamic plantar pressure redistribution patterns as evaluated by a pressure insole system. The results showed that a combination of rocker shoes and foot orthoses produced a significantly lower visual analog scale pain score (9.7 mm) than rocker shoes (30.9 mm) and foot orthoses (29.5 mm). With regard to baseline shoes, it also significantly reduced the greatest amount of medial heel peak pressure (-33.58%) without overloading other plantar regions when compared to rocker shoes (-7.99%) and foot orthoses (-28.82%). The findings indicate that a combined prescription of rocker sole shoes and custom-made foot orthoses had greater immediate therapeutic effects compared to when each treatment had been individually prescribed. Copyright © 2012 Elsevier Ltd. All rights reserved.

The Great Melting Pot. Common Sole Population Connectivity Assessed by Otolith and Water Fingerprints

PubMed Central

Morat, Fabien; Letourneur, Yves; Dierking, Jan; Pécheyran, Christophe; Bareille, Gilles; Blamart, Dominique; Harmelin-Vivien, Mireille

2014-01-01

Quantifying the scale and importance of individual dispersion between populations and life stages is a key challenge in marine ecology. The common sole (Solea solea), an important commercial flatfish in the North Sea, Atlantic Ocean and the Mediterranean Sea, has a marine pelagic larval stage, a benthic juvenile stage in coastal nurseries (lagoons, estuaries or shallow marine areas) and a benthic adult stage in deeper marine waters on the continental shelf. To date, the ecological connectivity among these life stages has been little assessed in the Mediterranean. Here, such an assessment is provided for the first time for the Gulf of Lions, NW Mediterranean, based on a dataset on otolith microchemistry and stable isotopic composition as indicators of the water masses inhabited by individual fish. Specifically, otolith Ba/Ca and Sr/Ca profiles, and δ13C and δ18O values of adults collected in four areas of the Gulf of Lions were compared with those of young-of-the-year collected in different coastal nurseries. Results showed that a high proportion of adults (>46%) were influenced by river inputs during their larval stage. Furthermore Sr/Ca ratios and the otolith length at one year of age revealed that most adults (∼70%) spent their juvenile stage in nurseries with high salinity, whereas the remainder used brackish environments. In total, data were consistent with the use of six nursery types, three with high salinity (marine areas and two types of highly saline lagoons) and three brackish (coastal areas near river mouths, and two types of brackish environments), all of which contributed to the replenishment of adult populations. These finding implicated panmixia in sole population in the Gulf of Lions and claimed for a habitat integrated management of fisheries. PMID:24475151

CD10-/ALDH- cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy.

PubMed

Ffrench, Brendan; Gasch, Claudia; Hokamp, Karsten; Spillane, Cathy; Blackshields, Gordon; Mahgoub, Thamir Mahmoud; Bates, Mark; Kehoe, Louise; Mooney, Aoibhinn; Doyle, Ronan; Doyle, Brendan; O'Donnell, Dearbhaile; Gleeson, Noreen; Hennessy, Bryan T; Stordal, Britta; O'Riain, Ciaran; Lambkin, Helen; O'Toole, Sharon; O'Leary, John J; Gallagher, Michael F

2017-10-19

It is long established that tumour-initiating cancer stem cells (CSCs) possess chemoresistant properties. However, little is known of the mechanisms involved, particularly with respect to the organisation of CSCs as stem-progenitor-differentiated cell hierarchies. Here we aimed to elucidate the relationship between CSC hierarchies and chemoresistance in an ovarian cancer model. Using a single cell-based approach to CSC discovery and validation, we report a novel, four-component CSC hierarchy based around the markers cluster of differentiation 10 (CD10) and aldehyde dehydrogenase (ALDH). In a change to our understanding of CSC biology, resistance to chemotherapy drug cisplatin was found to be the sole property of CD10 - /ALDH - CSCs, while all four CSC types were sensitive to chemotherapy drug paclitaxel. Cisplatin treatment quickly altered the hierarchy, resulting in a three-component hierarchy dominated by the cisplatin-resistant CD10 - /ALDH - CSC. This organisation was found to be hard-wired in a long-term cisplatin-adapted model, where again CD10 - /ALDH - CSCs were the sole cisplatin-resistant component, and all CSC types remained paclitaxel-sensitive. Molecular analysis indicated that cisplatin resistance is associated with inherent- and adaptive-specific drug efflux and DNA-damage repair mechanisms. Clinically, low CD10 expression was consistent with a specific set of ovarian cancer patient samples. Collectively, these data advance our understanding of the relationship between CSC hierarchies and chemoresistance, which was shown to be CSC- and drug-type specific, and facilitated by specific and synergistic inherent and adaptive mechanisms. Furthermore, our data indicate that primary stage targeting of CD10 - /ALDH - CSCs in specific ovarian cancer patients in future may facilitate targeting of recurrent disease, before it ever develops.

Early Ethanol and Water Consumption: Accumulating Experience Differentially Regulates Drinking Pattern and Bout Parameters in Male Alcohol Preferring (P) vs. Wistar and Sprague Dawley Rats

PubMed Central

Azarov, Alexey V.; Woodward, Donald J.

2013-01-01

Alcohol-preferring (P) rats develop high ethanol intake over several weeks of water/10% ethanol (10E) choice drinking. However, it is not yet clear precisely what components of drinking behavior undergo modification to achieve higher intake. Our concurrent report compared precisely measured daily intake in P vs. non-selected Wistar and Sprague Dawley (SD) rats. Here we analyze their drinking patterns and bouts to clarify microbehavioral components that are common to rats of different origin, vs. features that are unique to each. Under sole-fluid conditions P, Wistar and SD rats all consumed water at a high initial rate followed by a slow maintenance phase, but 10E - in a distinctly different step-like pattern of evenly distributed bouts. During choice period, 10E vs. water patterns for P rat appeared as an overlap of sole-fluid patterns. The SD rat choice patterns resembled sole-fluid patterns but were less regular. Choice patterns in Wistar differed from both P and SD rats, by consisting of intermixed small frequent episodes of drinking both 10E and water. Wistar and SD rats increased choice ethanol intake by elevating the number of bouts. A key finding was that P rat increased choice ethanol intake through a gradual increase of the bout size and duration, but kept bout number constant. This supports the hypothesis that genetic selection modifies microbehavioral machinery controlling drinking bout initiation, duration, and other pattern features. Precision analysis of drinking patterns and bouts allows differentiation between genetic lines, and provides a venue for study of localized circuit and transmitter influences mediating mesolimbic control over ethanol consumption. PMID:24095931

Gravitation Theory: Empirical Status from Solar System Experiments: All observations to date are consistent with Einstein's general relativity theory of gravity.

PubMed

Nordtvedt, K L

1972-12-15

I have reviewed the historical and contemporary experiments that guide us in choosing a post-Newtonian, relativistic gravitational theory. The foundation experiments essentially constrain gravitation theory to be a metric theory in which matter couples solely to one gravitational field, the metric field, although other cosmological gravitational fields may exist. The metric field for any metric theory can be specified (for the solar system, for our present purposes) by a series of potential terms with several parameters. A variety of experiments specify (or put limits on) the numerical values of the seven parameters in the post-Newtonian metric field, and other such experiments have been planned. The empirical results, to date, yield values of the parameters that are consistent with the predictions of Einstein's general relativity.

Severe dysphagia as the presenting symptom of Wernicke-Korsakoff syndrome in a non-alcoholic man.

PubMed

Karaiskos, Ilias; Katsarolis, Ioannis; Stefanis, Leonidas

2008-02-01

We present the case of a non-alcoholic man, who, following severe malnutrition, presented with dysphagia that necessitated gastrostomy tube placement. The patient subsequently developed encephalopathy, at which point thiamine deficiency was suspected and thiamine supplementation initiated. The encephalopathy and the dysphagia resolved, but the patient was left with a dense amnestic deficit consistent with Korsakoff syndrome. MRI at the time of the encephalopathy revealed lesions consistent with Wernicke-Korsakoff syndrome. This case represents a remarkable example of Wernicke-Korsakoff syndrome that for a prolonged time period had as its sole manifestation severe dysphagia. To our knowledge, there is only one similar case reported in the literature. This case serves to alert neurologists that isolated dysphagia may be the presenting symptom of this classic neurological syndrome even in the absence of alcoholism.

Occupational rhinitis and occupational asthma; one airway two diseases?

NASA Astrophysics Data System (ADS)

Seed, M. J.; Gittins, M.; DeVocht, F.; Agius, R. M.

2009-02-01

The concept of 'one airway, one disease' refers to the frequent comorbidity of asthma and rhinitis. However, only limited research has been done on this association for the diverse range of occupational respiratory sensitisers. The relative frequency of rhinitis was determined for the 15 respiratory sensitisers reported to cause at least 10 cases of rhinitis or asthma to The Health and Occupation Reporting (THOR) network between 1997 and 2006. Of 1408 cases, 1190 were sole diagnoses of asthma, 138 sole diagnoses of rhinitis and in 80 cases asthma coexisted with rhinitis. The six sensitisers for which rhinitis featured in over 15% of cases were all particulates and known to cause release of mast cell mediators, either directly or through IgE antibodies. Four of the other nine sensitisers often exist as vapours and only two have been consistently associated with IgE-mediated disease mechanisms. Particle size did not appear to correlate with the relative frequency of rhinitis. Despite its limitations this study would support the hypothesis that there are at least two mechanistic categories of respiratory sensitisation with rhinitis being relatively more common where the mechanism is IgE-mediated. Particulate nature may be another important factor to consider in future studies.

Uptake of Sulfate but Not Phosphate by Mycobacterium tuberculosis Is Slower than That for Mycobacterium smegmatis

PubMed Central

Song, Houhui

2012-01-01

Knowledge of the metabolic pathways used by Mycobacterium tuberculosis during infection is important for understanding its nutrient requirements and host adaptation. However, uptake, the first step in the utilization of nutrients, is poorly understood for many essential nutrients, such as inorganic anions. Here, we show that M. tuberculosis utilizes nitrate as the sole nitrogen source, albeit at lower efficiency than asparagine, glutamate, and arginine. The growth of the porin triple mutant M. smegmatis ML16 in media with limiting amounts of nitrate and sulfate as sole nitrogen and sulfur sources, respectively, was delayed compared to that of the wild-type strain. The uptake of sulfate was 40-fold slower than that of the wild-type strain, indicating that the efficient uptake of these anions is dependent on porins. The uptake by M. tuberculosis of sulfate and phosphate was approximately 40- and 10-fold slower than that of M. smegmatis, respectively, which is consistent with the slower growth of M. tuberculosis. However, the uptake of these anions by M. tuberculosis is orders of magnitude faster than diffusion through lipid membranes, indicating that unknown outer membrane proteins are required to facilitate this process. PMID:22194452

Alternative Fuel Research in Fischer-Tropsch Synthesis

NASA Technical Reports Server (NTRS)

Surgenor, Angela D.; Klettlinger, Jennifer L.; Yen, Chia H.; Nakley, Leah M.

2011-01-01

NASA Glenn Research Center has recently constructed an Alternative Fuels Laboratory which is solely being used to perform Fischer-Tropsch (F-T) reactor studies, novel catalyst development and thermal stability experiments. Facility systems have demonstrated reliability and consistency for continuous and safe operations in Fischer-Tropsch synthesis. The purpose of this test facility is to conduct bench scale Fischer-Tropsch (F-T) catalyst screening experiments while focusing on reducing energy inputs, reducing CO2 emissions and increasing product yields within the F-T process. Fischer-Tropsch synthesis is considered a gas to liquid process which reacts syn-gas (a gaseous mixture of hydrogen and carbon monoxide), over the surface of a catalyst material which is then converted into liquids of various hydrocarbon chain length and product distributions1. These hydrocarbons can then be further processed into higher quality liquid fuels such as gasoline and diesel. The experiments performed in this laboratory will enable the investigation of F-T reaction kinetics to focus on newly formulated catalysts, improved process conditions and enhanced catalyst activation methods. Currently the facility has the capability of performing three simultaneous reactor screening tests, along with a fourth fixed-bed reactor used solely for cobalt catalyst activation.

Emerging Connections: Quantum & Classical Optics Incubator Program Book

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lesky, Marcia

The Emerging Connections: Quantum & Classical Optics Incubator was a scientific meeting held in Washington, DC on 6-8 November 2016. This Incubator provided unique and focused experiences and valuable opportunities to discuss advances, challenges and opportunities regarding this important area of research. Quantum optics and classical optics have coexisted for nearly a century as two distinct, but consistent descriptions of light in their respective domains. Recently, a number of detailed examinations of the structure of classical light beams have revealed that effects widely thought to be solely quantum in origin also have a place in classical optics. These new quantum-classicalmore » connections are informing classical optics in meaningful ways specifically by expanding understanding of optical coherence. Simultaneously, relationships discovered with classical light beams now also serve as a vehicle to illuminate concepts that no longer solely belong to the quantum realm. Interference, polarization, coherence, complementarity and entanglement are a partial list of elementary notions that now appear to belong to both quantum and classical optics. The goal of this meeting was to bring emerging quantum-classical links into wider view and to indicate directions in which forthcoming and future work would promote discussion and lead to a more unified understanding of optics.« less

Defining Staged Procedures for Percutaneous Coronary Intervention Trials: A Guidance Document.

PubMed

Spitzer, Ernest; McFadden, Eugène; Vranckx, Pascal; de Vries, Ton; Ren, Ben; Collet, Carlos; Onuma, Yoshinobu; Garcia-Garcia, Hector M; Lopes, Renato D; Stone, Gregg W; Cutlip, Donald E; Serruys, Patrick W

2018-05-14

Patients in coronary intervention trials may require more than 1 procedure to complete the intended revascularization strategy. However, these staged interventions are not consistently defined. Standardized definitions are needed to allow meaningful comparisons of this outcome among trials. This document provides guidance on relevant parameters involving staged procedures, including minimum data collection and consistent classification of coronary procedures initially identified as staged; the aim is to achieve consistency among clinical trialists, sponsors, health authorities, and regulators. Definitions were developed jointly among representatives of academic institutions and clinical research organizations based on clinical trial experience and published literature. Reasons for staged procedures were identified and include baseline kidney function, contrast load and radiation exposure, lesion complexity, and patient or operator fatigue. Moreover, nonclinical reasons include procedure scheduling and reimbursement. Management of staged procedures should be a standalone section in clinical trial protocols and clinical events committee charters. These documents should clearly define a time window for staged procedures that allows latitude for local policies, while respecting accepted clinical guidelines, and consistency with study objectives. Investigators should document in the case report form the intent to stage a procedure, the lesions to be treated, and the reasons for staging, preferably before randomization. Ideally, all reinterventions, or at least all procedures performed after the recommended time window, those in which data suggest an anticipated procedure due to a worsening condition and those where a revascularization is attempted in the target vessel, should be reviewed by an independent clinical events committee. Copyright © 2018 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

31 CFR 360.36 - Payment during life of sole owner.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Payment during life of sole owner. 360.36 Section 360.36 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... UNITED STATES SAVINGS BONDS, SERIES I General Provisions for Payment § 360.36 Payment during life of sole...

78 FR 54652 - Sole Source Cooperative Agreement Award to the Association for State and Territorial Health...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Sole Source Cooperative Agreement Award to the Association...: Notification of a Sole Source Cooperative Agreement Award to the Association for State and Territorial Health... management systems. One of the overarching goals of both the National Health Security Strategy (2009) and the...

78 FR 54651 - Sole Source Cooperative Agreement Award to the National Association of County and City Health...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Sole Source Cooperative Agreement Award to the National...: Notification of a Sole Source Cooperative Agreement Award to the National Association of County and City Health... resilience, and strengthen health care, public health, and emergency management systems. One of the...

SOLE: enhanced FIA data analysis capabilities

Treesearch

Michael Spinney; Paul Van Deusen

2009-01-01

The Southern On Line Estimator (SOLE), is an Internet-based annual forest inventory and analysis (FIA) data analysis tool developed cooperatively by the National Council for Air and Stream Improvement and the Forest Service, U.S. Department of Agriculture's Forest Inventory and Analysis program at the Southern Research Station. Recent development of SOLE has...

What Makes a Good Summary?

NASA Astrophysics Data System (ADS)

Zhao, Qunhua; Santos, Eugene; Nguyen, Hien; Mohamed, Ahmed

One of the biggest challenges for intelligence analysts who participate in prevention or response to a terrorism act is to quickly find relevant information from massive amounts of data. Along with research on information retrieval and filtering, text summarization is an effective technique to help intelligence analysts shorten their time to find critical information and make timely decisions. Multi-document summarization is particularly useful as it serves to quickly describe a collection of information. The obvious shortcoming lies in what it cannot capture especially in more diverse collections. Thus, the question lies in the adequacy and/or usefulness of such summarizations to the target analyst. In this chapter, we report our experimental study on the sensitivity of users to the quality and content of multi-document summarization. We used the DUC 2002 collection for multi-document summarization as our testbed. Two groups of document sets were considered: (I) the sets consisting of closely correlated documents with highly overlapped content; and (II) the sets consisting of diverse documents covering a wide scope of topics. Intuitively, this suggests that creating a quality summary would be more difficult for the latter case. However, human evaluators were discovered to be fairly insensitive to this difference. This occurred when they were asked to rank the performance of various automated summarizers. In this chapter, we examine and analyze our experiments in order to better understand this phenomenon and how we might address it to improve summarization quality. In particular, we present a new metric based on document graphs that can distinguish between the two types of document sets.

14 CFR 16.13 - Filing of documents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... knowledge, information, and belief, the document is— (1) Consistent with this part; (2) Warranted by... proceeding. If any of these items change during the proceeding, the person shall promptly file notice of the change with the FAA Part 16 Airport Proceedings Docket and the hearing officer and shall serve the notice...

3 CFR - Continuation of the National Emergency With Respect to Certain Terrorist Attacks

Code of Federal Regulations, 2013 CFR

2013-01-01

... 3 The President 1 2013-01-01 2013-01-01 false Continuation of the National Emergency With Respect to Certain Terrorist Attacks Presidential Documents Other Presidential Documents Notice of September 11, 2012 Continuation of the National Emergency With Respect to Certain Terrorist Attacks Consistent...

3 CFR - Continuation of the National Emergency With Respect to Certain Terrorist Attacks

Code of Federal Regulations, 2012 CFR

2012-01-01

... 3 The President 1 2012-01-01 2012-01-01 false Continuation of the National Emergency With Respect to Certain Terrorist Attacks Presidential Documents Other Presidential Documents Notice of September 9, 2011 Continuation of the National Emergency With Respect to Certain Terrorist Attacks Consistent...

Communication Skills for Workplace Assessors.

ERIC Educational Resources Information Center

Corbett, Deborah

This document is designed to help develop the communication skills of individuals training for the position of workplace assessor in Australia's National Training Framework and practicing workplace assessors who require additional assistance with on-the-job communication skills. The document consists of 11 units of study that each contain some or…

46 CFR 68.65 - Annual ownership certification.

Code of Federal Regulations, 2014 CFR

2014-10-01

... coastwise endorsement under § 68.60 must certify in writing to the Director, National Vessel Documentation... leasing company, bank, or financial institution; (ii) Owns, or holds the beneficial interest in, the... person and its United States affiliates and documented under 46 U.S.C. 12106 consists of oil, petroleum...

46 CFR 68.65 - Annual ownership certification.

Code of Federal Regulations, 2012 CFR

2012-10-01

... coastwise endorsement under § 68.60 must certify in writing to the Director, National Vessel Documentation... leasing company, bank, or financial institution; (ii) Owns, or holds the beneficial interest in, the... person and its United States affiliates and documented under 46 U.S.C. 12106 consists of oil, petroleum...

46 CFR 68.65 - Annual ownership certification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... coastwise endorsement under § 68.60 must certify in writing to the Director, National Vessel Documentation... leasing company, bank, or financial institution; (ii) Owns, or holds the beneficial interest in, the... person and its United States affiliates and documented under 46 U.S.C. 12106 consists of oil, petroleum...

46 CFR 68.65 - Annual ownership certification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... coastwise endorsement under § 68.60 must certify in writing to the Director, National Vessel Documentation... leasing company, bank, or financial institution; (ii) Owns, or holds the beneficial interest in, the... person and its United States affiliates and documented under 46 U.S.C. 12106 consists of oil, petroleum...

46 CFR 68.65 - Annual ownership certification.

Code of Federal Regulations, 2013 CFR

2013-10-01

... coastwise endorsement under § 68.60 must certify in writing to the Director, National Vessel Documentation... leasing company, bank, or financial institution; (ii) Owns, or holds the beneficial interest in, the... person and its United States affiliates and documented under 46 U.S.C. 12106 consists of oil, petroleum...

The Myth and Reality of Aging in America.

ERIC Educational Resources Information Center

National Council on the Aging, Inc., Washington, DC.

To understand and document the image and the reality of old age and older Americans, the National Council on the Aging (NCOA) commissioned the major, in-depth survey which examined public attitudes and expectations and documented older Americans' views and personal experiences. Consisting of statistical tables, textual analysis, and subjective…

A Citizen-Science Study Documents Environmental Exposures and Asthma Prevalence in Two Communities

EPA Science Inventory

A citizen-science study was conducted in two low-income, flood-prone communities in Atlanta, Georgia, in order to document environmental exposures and the prevalence of occupant asthma. Teams consisting of a public-health graduate student and a resident from one of the two commun...

Continuous Improvement in Online Education: Documenting Teaching Effectiveness in the Online Environment through Observations

ERIC Educational Resources Information Center

Purcell, Jennifer W.; Scott, Heather I.; Mixson-Brookshire, Deborah

2017-01-01

Teaching observations are commonly used among educators to document and improve teaching effectiveness. Unfortunately, the necessary protocols and supporting infrastructure are not consistently available for faculty who teach online. This paper presents a brief literature review and reflective narratives of educators representing online education…

Managing School Social Work Records

ERIC Educational Resources Information Center

Garrett, Kendra J.

2012-01-01

This article documents results of a survey of 73 school social workers regarding their record-keeping practices. These social workers indicated that time pressures are a major challenge to documentation; they struggle to know what to include, and they worry about privacy. More than half fail to consistently include assessment information, progress…

42 CFR 426.518 - NCD record furnished to the aggrieved party.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM REVIEW OF NATIONAL COVERAGE DETERMINATIONS AND LOCAL... section, the NCD record consists of any document or material that CMS considered during the development of... decision memoranda. (5) An index of documents considered that are excluded under paragraph (b) of this...

42 CFR 426.518 - NCD record furnished to the aggrieved party.

Code of Federal Regulations, 2011 CFR

2011-10-01

... HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM REVIEW OF NATIONAL COVERAGE DETERMINATIONS AND LOCAL... section, the NCD record consists of any document or material that CMS considered during the development of... decision memoranda. (5) An index of documents considered that are excluded under paragraph (b) of this...

Intracranial hypertension in a dieting patient.

PubMed

Sirdofsky, M; Kattah, J; Macedo, P

1994-03-01

We report a case of encephalopathy with paranoid psychosis in association with intracranial hypertension. This occurred in a patient whose diet consisted almost solely of walnuts, ginseng tea, and vitamin A supplements. The patient was found to be severely iron- and vitamin B12-deficient. She was vitamin A toxic. Venous sinus thrombosis was also present. Symptoms remitted with serial lumbar punctures, normalization of diet, and repletion of vitamin B12 and iron stores. Physicians should be alerted to the possibility of a potentially confusing clinical presentation with coexistent and seemingly mutually exclusive neurologic conditions in patients with extremely restricted or fad diets.

Object-based selection in the Baylis and Driver (1993) paradigm is subject to space-based attentional modulation.

PubMed

Müller, Hermann J; O'Grady, Rebecca; Krummenacher, Joseph; Heller, Dieter

2008-11-01

Three experiments re-examined Baylis and Driver's (1993) strong evidence for object-based selection, that making relative apex location judgments is harder between two objects than within a single object, with object (figure-ground) segmentation determined solely by color-based perceptual set. Using variations of the Baylis and Driver paradigm, the experiments replicated a two-object cost. However, they also showed a large part of the two-object cost to be attributable to space-based factors, though there remained an irreducible cost consistent with 'true' object-based selection.

Spousal Employment and Intra-Household Bargaining Power.

PubMed

Antman, Francisca M

2014-05-01

This paper considers the relationship between work status and decision-making power of the head of household and his spouse. I use household fixed effects models to address the possibility that spousal work status maybe correlated with unobserved factors that also affect bargaining power within the home. Consistent with the hypothesis that greater economic resources yield greater bargaining power, I find that the spouse of the head of household is more likely to be involved in decisions when she has been employed. Similarly, the head of household is less likely to be the sole decision-maker when his spouse works.

Spousal Employment and Intra-Household Bargaining Power*

PubMed Central

Antman, Francisca M.

2014-01-01

This paper considers the relationship between work status and decision-making power of the head of household and his spouse. I use household fixed effects models to address the possibility that spousal work status maybe correlated with unobserved factors that also affect bargaining power within the home. Consistent with the hypothesis that greater economic resources yield greater bargaining power, I find that the spouse of the head of household is more likely to be involved in decisions when she has been employed. Similarly, the head of household is less likely to be the sole decision-maker when his spouse works. PMID:25342928

Modelling the transport of common sole larvae in the southern North Sea: Influence of hydrodynamics and larval vertical movements

NASA Astrophysics Data System (ADS)

Savina, Marie; Lacroix, Geneviève; Ruddick, Kevin

2010-04-01

In the present work we used a particle-tracking model coupled to a 3D hydrodynamic model to study the combined effect of hydrodynamic variability and active vertical movements on the transport of sole larvae in the southern North Sea. Larval transport from the 6 main spawning grounds was simulated during 40 day periods starting on 2 plausible spawning dates, the 15/04 and the 01/05, during 2 years, 1995 and 1996. In addition to a "passive" behaviour, 3 types of active vertical movements inspired from previous studies have been tested: (1) Eggs and early larvae float in the surface waters, late larvae migrate toward the bottom and stay there until the end of the simulation; (2 and 3) Eggs float in the surface waters, early larvae perform diel vertical migrations in the surface waters, and (2) Late larvae perform diel vertical migrations in the bottom waters until the end of the simulation; or (3) Late larvae perform tidally synchronised vertical migrations in the bottom waters until the end of the simulation. These behaviours have been implemented in the model with vertical migration rates, positive or negative, which can account for buoyancy or real swimming activity. Variations in larval transport were analysed in terms of mean trajectories, final larvae distribution, larval retention above nurseries, and connectivity. Results suggest that the variations in larval retention above nurseries due to the varying hydrodynamic conditions are not consistent in space i.e. not the same for all the spawning sites. The effect of active vertical movements on larval transport is also not consistent in space: Effects of active vertical movements include decreased retention above nurseries, decreased transport and/or decreased horizontal dispersion of larvae through reduced vertical shear (depending on the zone). The variability in larval retention due to hydrodynamic variability is higher than variability due to differences in the behaviour of larvae. In terms of connectivity, exchanges of larvae between the 6 areas considered are moderate: 10 connections happened out of the 30 possible, and the amount of larvae exchanged is much lower than the amount of larvae retained except in a few cases. This is not incompatible with the possible existence of subpopulations of sole in the Eastern Channel and southern North Sea.

Occurrence, distribution and prey items of juvenile marbled sole Pseudopleuronectes yokohamae around a submarine groundwater seepage on a tidal flat in southwestern Japan

NASA Astrophysics Data System (ADS)

Hata, Masaki; Sugimoto, Ryo; Hori, Masakazu; Tomiyama, Takeshi; Shoji, Jun

2016-05-01

Occurrence, distribution and prey items of juvenile marbled sole Pseudopleuronectes yokohamae were investigated around a submarine groundwater seepage on a tidal flat in southwestern Japan. Spatial distribution of radon-222 (222Rn) concentration in water showed more submarine groundwater seepage in the offshore area. The lower salinities at offshore sampling stations corresponded with the highest 222Rn concentrations. Juvenile marbled sole were collected from March through June with seasonal peak in April in 2013 and 2014. Mean abundance of juvenile marbled sole was highest at the second most offshore station where high submarine groundwater seepage was indicated. Major prey items in the stomachs of the marbled sole at the post-settlement stage (10-40 mm) were small crustaceans such as cumaceans and gammarids, which were partially replaced with polychaetes in larger juveniles (40-50 mm). Abundance of these major prey items was also higher at offshore stations. A negative correlation between gammarid abundance and salinity indicated a higher concentration of gammarids around the area of high submarine groundwater seepage, a pattern not observed for the other major prey organisms. Stable isotope analysis showed greater dependence of post-settlement stage marbled sole on the small crustaceans with low δ13C indicating that nutrients of terrestrial origin contribute to production of the juvenile marbled sole on the tidal flat.

Digenean metacercariae parasites as natural tags of habitat use by 0-group common sole Solea solea in nearshore coastal areas: A case study in the embayed system of the Pertuis Charentais (Bay of Biscay, France)

NASA Astrophysics Data System (ADS)

Durieux, Eric D. H.; Bégout, Marie-Laure; Pinet, Patrick; Sasal, Pierre

2010-07-01

This study focused on the spatio-temporal variation in the host-parasite system, 0-group sole-digenean metacercariae, in nearshore coastal areas at relatively small spatial scale. 0-group soles were sampled using a standard beam trawl in April, May, June, August and October 2005 at nine different sites in the Pertuis Charentais area (Bay of Biscay, France). Sole density, size, Fulton's condition factor K and digenean metacercariae communities were analysed. 0-group sole concentrated in shallow and muddy areas where they accumulated digenean metacercariae. Parasite communities displayed strong spatial patterns tightly linked to the distribution of the first intermediate mollusc hosts. These parasitological data suggest that 0-group sole during their first period of growth are mainly sedentary with limited movements between the different parts of the habitat. Size and density data revealed spatial heterogeneity in terms of habitat quality so that a limited zone (Aiguillon Bay) within the study area could be identified as sensu stricto nursery habitat for 0-group sole. The use of digenean metacercariae as natural tags appears as a novel powerful tool to evaluate habitat use and movements of juvenile flatfish, which could find applications in fisheries and coastal zone management programs.

Therapeutic value of selective salpingography for infertile women with patent fallopian tubes: the impact on pregnancy rate.

PubMed

Kamiyama, S; Miyagi, H; Kanazawa, K

2000-01-01

To determine the therapeutic value of selective salpingography (SSG) for infertile women with patent fallopian tubes. Retrospective, case-control analysis. University Hospital, infertility clinic. Infertile cases with patent tubes documented by hysterosalpingography (HSG) or by HSG followed by laparoscopic examination (n = 80). Hysteroscopic SSG. Patency rate of tubes by SSG. Pregnancy rate following SSG. Eighty cases were divided into the study group (SSG performed, 37 cases) and the case-control group (SSG not performed, 43 cases). Successful SSG of at least one tube was obtained in all of 37 cases (100%) in whom SSG was attempted. A patency rate of 95.9% was documented in the 73 cannulated tubes of these cases. The total subsequent pregnancy rate (48.6%) within 12 months of follow-up after SSG was significantly higher than that (11.6%) obtained in the control group (p < 0.001). The cumulative pregnancy rate in the study group was also significantly higher than that in the control group (p < 0.001). The findings of the present study encourage the application of SSG to infertile women, either as a sole therapeutic approach or in association with other methods of assisted reproductive technology, even if their fallopian tubes are shown to be patent by HSG. Copyright 2000 S. Karger AG, Basel

Robust Inference of Genetic Exchange Communities from Microbial Genomes Using TF-IDF.

PubMed

Cong, Yingnan; Chan, Yao-Ban; Phillips, Charles A; Langston, Michael A; Ragan, Mark A

2017-01-01

Bacteria and archaea can exchange genetic material across lineages through processes of lateral genetic transfer (LGT). Collectively, these exchange relationships can be modeled as a network and analyzed using concepts from graph theory. In particular, densely connected regions within an LGT network have been defined as genetic exchange communities (GECs). However, it has been problematic to construct networks in which edges solely represent LGT. Here we apply term frequency-inverse document frequency (TF-IDF), an alignment-free method originating from document analysis, to infer regions of lateral origin in bacterial genomes. We examine four empirical datasets of different size (number of genomes) and phyletic breadth, varying a key parameter (word length k ) within bounds established in previous work. We map the inferred lateral regions to genes in recipient genomes, and construct networks in which the nodes are groups of genomes, and the edges natively represent LGT. We then extract maximum and maximal cliques (i.e., GECs) from these graphs, and identify nodes that belong to GECs across a wide range of k . Most surviving lateral transfer has happened within these GECs. Using Gene Ontology enrichment tests we demonstrate that biological processes associated with metabolism, regulation and transport are often over-represented among the genes affected by LGT within these communities. These enrichments are largely robust to change of k .

Confocal Raman imaging and chemometrics applied to solve forensic document examination involving crossed lines and obliteration cases by a depth profiling study.

PubMed

Borba, Flávia de Souza Lins; Jawhari, Tariq; Saldanha Honorato, Ricardo; de Juan, Anna

2017-03-27

This article describes a non-destructive analytical method developed to solve forensic document examination problems involving crossed lines and obliteration. Different strategies combining confocal Raman imaging and multivariate curve resolution-alternating least squares (MCR-ALS) are presented. Multilayer images were acquired at subsequent depth layers into the samples. It is the first time that MCR-ALS is applied to multilayer images for forensic purposes. In this context, this method provides a single set of pure spectral ink signatures and related distribution maps for all layers examined from the sole information in the raw measurement. Four cases were investigated, namely, two concerning crossed lines with different degrees of ink similarity and two related to obliteration, where previous or no knowledge about the identity of the obliterated ink was available. In the crossing line scenario, MCR-ALS analysis revealed the ink nature and the chronological order in which strokes were drawn. For obliteration cases, results making active use of information about the identity of the obliterated ink in the chemometric analysis were of similar quality as those where the identity of the obliterated ink was unknown. In all obliteration scenarios, the identity of inks and the obliterated text were satisfactorily recovered. The analytical methodology proposed is of general use for analytical forensic document examination problems, and considers different degrees of complexity and prior available information. Besides, the strategies of data analysis proposed can be applicable to any other kind of problem in which multilayer Raman images from multicomponent systems have to be interpreted.

31 CFR 315.36 - Payment during life of sole owner.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Payment during life of sole owner. 315.36 Section 315.36 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... § 315.36 Payment during life of sole owner. A savings bond registered in single ownership form (i.e...

75 FR 76352 - Fisheries of the Exclusive Economic Zone Off Alaska; Gulf of Alaska; Proposed 2011 and 2012...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-08

... for 2011 and 2012 that are equal to proposed ABCs for pollock, deep-water flatfish, rex sole... certain species: Pacific cod, flathead sole, shallow-water flatfish, arrowtooth flounder, and other... that the ABC is not exceeded. The flathead sole, shallow-water flatfish, and arrowtooth flounder TACs...

"Newstart" or "Stop-Start"? the Implications of Recent Welfare Reforms on Undergraduate Students Who Are Sole Parents

ERIC Educational Resources Information Center

Lenette, Caroline; McDonald, Donna; Fowler, Jane L.

2014-01-01

This article discusses the implications of recent income support payment changes for sole-parented families in Australia, and in particular, their capacity to access tertiary education. The government's program to reduce welfare benefit payments to sole-parented families already at high risk of economic disadvantage and social marginalization…

Challenges of working with FIADB17 data: the SOLE experience

Treesearch

Michael Spinney; Paul Van Deusen

2007-01-01

The Southern On Line Estimator (SOLE) is an Internet-based Forest Inventory and Analysis (FIA) data analysis tool. SOLE is based on data downloaded from the publicly available FIA database (FIADB) and summarized by plot condition. The tasks of downloading, processing, and summarizing FIADB data require specialized expertise in inventory theory and data manipulation....

75 FR 76372 - Fisheries of the Exclusive Economic Zone Off Alaska; Bering Sea and Aleutian Islands; Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-08

... intends to have the information available for the assessment cycle in the fall of 2011. At the October... sole, rock sole, Kamchatka flounder, sharks, squid, sculpins, and octopus to be included in the final... flounder, Greenland turbot, rock sole, Alaska plaice, other flatfish, and rougheye rockfish. The biomass...

IDC Re-Engineering Phase 2 System Specification Document Version 1.5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Satpathi, Meara Allena; Burns, John F.; Harris, James M.

This document contains the system specifications derived to satisfy the system requirements found in the IDC System Requirements Document for the IDC Re-Engineering Phase 2 project. This System Specification Document (SSD) defines waveform data processing requirements for the International Data Centre (IDC) of the Comprehensive Nuclear Test Ban Treaty Organization (CTBTO). The routine processing includes characterization of events with the objective of screening out events considered to be consistent with natural phenomena or non-nuclear, man-made phenomena. This document does not address requirements concerning acquisition, processing and analysis of radionuclide data but does include requirements for the dissemination of radionuclide datamore » and products.« less

Spatial Paradigm for Information Retrieval and Exploration

DOE Office of Scientific and Technical Information (OSTI.GOV)

The SPIRE system consists of software for visual analysis of primarily text based information sources. This technology enables the content analysis of text documents without reading all the documents. It employs several algorithms for text and word proximity analysis. It identifies the key themes within the text documents. From this analysis, it projects the results onto a visual spatial proximity display (Galaxies or Themescape) where items (documents and/or themes) visually close to each other are known to have content which is close to each other. Innovative interaction techniques then allow for dynamic visual analysis of large text based information spaces.

SPIRE1.03. Spatial Paradigm for Information Retrieval and Exploration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, K.J.; Bohn, S.; Crow, V.

The SPIRE system consists of software for visual analysis of primarily text based information sources. This technology enables the content analysis of text documents without reading all the documents. It employs several algorithms for text and word proximity analysis. It identifies the key themes within the text documents. From this analysis, it projects the results onto a visual spatial proximity display (Galaxies or Themescape) where items (documents and/or themes) visually close to each other are known to have content which is close to each other. Innovative interaction techniques then allow for dynamic visual analysis of large text based information spaces.

Allen's big-eared bat (Idionycteris phyllotis) documented in colorado based on recordings of its distinctive echolocation call

USGS Publications Warehouse

Hayes, M.A.; Navo, K.W.; Bonewell, L.; Mosch, C.J.; Adams, Rick A.

2009-01-01

Allen's big-eared bat (Idionycteris phyllotis) inhabits much of the southwestern USA, but has not been documented in Colorado. We recorded echolocation calls consistent with I. phyllotis near La Sal Creek, Montrose County, Colorado. Based on characteristics of echolocation calls and flight behavior, we conclude that the echolocation calls described here were emitted by I. phyllotis and that they represent the first documentation of this species in Colorado.

Documenting How States Recently Upgraded to Primary Seat Belt Laws

DOT National Transportation Integrated Search

2011-09-01

States with primary seat belt enforcement laws consistently have higher observed daytime belt use rates than : secondary law States. Secondary belt law States, on the other hand, consistently have more occupant fatalities who : were not restrained th...

48 CFR 52.230-4 - Disclosure and Consistency of Cost Accounting Practices-Foreign Concerns.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Consistency of Cost Accounting Practices —Foreign Concerns (JUN 2010) (a) The Contractor, in connection with.... Government to examine and make copies of any documents, papers, and records relating to compliance with the...

Stiffness Effects in Rocker-Soled Shoes: Biomechanical Implications

PubMed Central

Su, Pei-Fang; Chung, Chia-Hua; Hsia, Chi-Chun; Chang, Chih-Han

2017-01-01

Rocker-soled shoes provide a way to reduce the possible concentration of stress, as well as change movement patterns, during gait. This study attempts to examine how plantar force and spatio-temporal variables are affected by two rocker designs, one with softer and one with denser sole materials, by comparing them with the barefoot condition and with flat-soled shoes. Eleven subjects’ gait parameters during walking and jogging were recorded. Our results showed that compared with barefoot walking, plantar forces were higher for flat shoes while lower for both types of rocker shoes, the softer-material rocker being the lowest. The plantar force of flat shoes is greater than the vertical ground reaction force, while that of both rocker shoes is much less, 13.87–30.55% body weight. However, as locomotion speed increased to jogging, for all shoe types, except at the second peak plantar force of the denser sole material rocker shoes, plantar forces were greater than for bare feet. More interestingly, because the transmission of force was faster while jogging, greater plantar force was seen in the rocker-soled shoes with softer material than with denser material; results for higher-speed shock absorption in rocker-soled shoes with softer material were thus not as good. In general, the rolling phenomena along the bottom surface of the rocker shoes, as well as an increase in the duration of simultaneous curve rolling and ankle rotation, could contribute to the reduction of plantar force for both rocker designs. The possible mechanism is the conversion of vertical kinetic energy into rotational kinetic energy. To conclude, since plantar force is related to foot-ground interface and deceleration methods, rocker-design shoes could achieve desired plantar force reduction through certain rolling phenomena, shoe-sole stiffness levels, and locomotion speeds. PMID:28046009

Stiffness Effects in Rocker-Soled Shoes: Biomechanical Implications.

PubMed

Lin, Shih-Yun; Su, Pei-Fang; Chung, Chia-Hua; Hsia, Chi-Chun; Chang, Chih-Han

2017-01-01

Rocker-soled shoes provide a way to reduce the possible concentration of stress, as well as change movement patterns, during gait. This study attempts to examine how plantar force and spatio-temporal variables are affected by two rocker designs, one with softer and one with denser sole materials, by comparing them with the barefoot condition and with flat-soled shoes. Eleven subjects' gait parameters during walking and jogging were recorded. Our results showed that compared with barefoot walking, plantar forces were higher for flat shoes while lower for both types of rocker shoes, the softer-material rocker being the lowest. The plantar force of flat shoes is greater than the vertical ground reaction force, while that of both rocker shoes is much less, 13.87-30.55% body weight. However, as locomotion speed increased to jogging, for all shoe types, except at the second peak plantar force of the denser sole material rocker shoes, plantar forces were greater than for bare feet. More interestingly, because the transmission of force was faster while jogging, greater plantar force was seen in the rocker-soled shoes with softer material than with denser material; results for higher-speed shock absorption in rocker-soled shoes with softer material were thus not as good. In general, the rolling phenomena along the bottom surface of the rocker shoes, as well as an increase in the duration of simultaneous curve rolling and ankle rotation, could contribute to the reduction of plantar force for both rocker designs. The possible mechanism is the conversion of vertical kinetic energy into rotational kinetic energy. To conclude, since plantar force is related to foot-ground interface and deceleration methods, rocker-design shoes could achieve desired plantar force reduction through certain rolling phenomena, shoe-sole stiffness levels, and locomotion speeds.

Biomechanical Effects of Prefabricated Foot Orthoses and Rocker‐Sole Footwear in Individuals With First Metatarsophalangeal Joint Osteoarthritis

PubMed Central

Auhl, Maria; Tan, Jade M.; Levinger, Pazit; Roddy, Edward; Munteanu, Shannon E.

2016-01-01

Objective To evaluate the effects of prefabricated foot orthoses and rocker‐sole footwear on spatiotemporal parameters, hip and knee kinematics, and plantar pressures in people with first metatarsophalangeal (MTP) joint osteoarthritis (OA). Methods. A total of 102 people with first MTP joint OA were randomly allocated to receive prefabricated foot orthoses or rocker‐sole footwear. The immediate biomechanical effects of the interventions (compared to usual footwear) were examined using a wearable sensor motion analysis system and an in‐shoe plantar pressure measurement system. Results Spatiotemporal/kinematic and plantar pressure data were available from 88 and 87 participants, respectively. The orthoses had minimal effect on spatiotemporal or kinematic parameters, while the rocker‐sole footwear resulted in reduced cadence, percentage of the gait cycle spent in stance phase, and sagittal plane hip range of motion. The orthoses increased peak pressure under the midfoot and lesser toes. Both interventions significantly reduced peak pressure under the first MTP joint, and the rocker‐sole shoes also reduced peak pressure under the second through fifth MTP joints and heel. When the effects of the orthoses and rocker‐sole shoes were directly compared, there was no difference in peak pressure under the hallux, first MTP joint, or heel; however, the rocker‐sole shoes exhibited lower peak pressure under the lesser toes, second through fifth MTP joints, and midfoot. Conclusion Prefabricated foot orthoses and rocker‐sole footwear are effective at reducing peak pressure under the first MTP joint in people with first MTP joint OA, but achieve this through different mechanisms. Further research is required to determine whether these biomechanical changes result in improvements in symptoms. PMID:26640157

Rocker-soled shoes and walking distance in patients with calf claudication.

PubMed

Richardson, J K

1991-07-01

Calf claudication is the major clinical manifestation of peripheral vascular occlusive disease in a significant number of patients. Although claudication causes substantial patient disability, most patients are treated conservatively because of the risks of surgical therapy and the uncertain efficacy of drug therapy. It was hypothesized that rocker-soled shoes would decrease the work of the plantar flexors and therefore increase walking distance in patients with calf claudication. To test this hypothesis, walking distances in patients with calf claudication using rocker-soled shoes and a placebo shoe insert were compared. Rocker-soled shoes significantly increased both the total distance walked and the distance at which patients were initially bothered by symptoms by 77m (37%, p less than .0005) and 89m (91%, p = .003), respectively. It was concluded that rocker-soled shoes may reduce disability in patients with calf claudication by increasing walking distance.

Spatial factors and muscle spindle input influence the generation of neuromuscular responses to stimulation of the human foot

NASA Astrophysics Data System (ADS)

Layne, Charles S.; Forth, Katharine E.; Abercromby, Andrew F. J.

2005-05-01

Removal of the mechanical pressure gradient on the soles leads to physiological adaptations that ultimately result in neuromotor degradation during spaceflight. We propose that mechanical stimulation of the soles serves to partially restore the afference associated with bipedal loading and assists in attenuating the negative neuromotor consequences of spaceflight. A dynamic foot stimulus device was used to stimulate the soles in a variety of conditions with different stimulation locations, stimulation patterns and muscle spindle input. Surface electromyography revealed the lateral side of the sole elicited the greatest neuromuscular response in ankle musculature, followed by the medial side, then the heel. These responses were modified by preceding stimulation. Neuromuscular responses were also influenced by the level of muscle spindle input. These results provide important information that can be used to guide the development of a "passive" countermeasure that relies on sole stimulation and can supplement existing exercise protocols during spaceflight.

Consistency of a counterexample to Naimark's problem

PubMed Central

Akemann, Charles; Weaver, Nik

2004-01-01

We construct a C*-algebra that has only one irreducible representation up to unitary equivalence but is not isomorphic to the algebra of compact operators on any Hilbert space. This answers an old question of Naimark. Our construction uses a combinatorial statement called the diamond principle, which is known to be consistent with but not provable from the standard axioms of set theory (assuming that these axioms are consistent). We prove that the statement “there exists a counterexample to Naimark's problem which is generated by \\documentclass[10pt]{article} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{pmc} \\usepackage[Euler]{upgreek} \\pagestyle{empty} \\oddsidemargin -1.0in \\begin{document} \\begin{equation*}{\\aleph}_{1}\\end{equation*}\\end{document} elements” is undecidable in standard set theory. PMID:15131270

75 FR 51185 - Fisheries of the Exclusive Economic Zone Off Alaska; Reallocation of Rock Sole in the Bering Sea...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-19

.... 0910131363-0087-02] RIN 0648-XY29 Fisheries of the Exclusive Economic Zone Off Alaska; Reallocation of Rock...; reallocation. SUMMARY: NMFS is reallocating the projected unused amount of the 2010 rock sole total allowable... necessary to allow the 2010 total allowable catch of rock sole to be fully harvested. DATES: Effective...

26 CFR 1.1033(e)-1 - Sale or exchange of livestock solely on account of drought.

Code of Federal Regulations, 2010 CFR

2010-04-01

... of drought. 1.1033(e)-1 Section 1.1033(e)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF... Sale or exchange of livestock solely on account of drought. (a) The sale or exchange of livestock... if the sale or exchange of such livestock by the taxpayer is solely on account of drought. Section...

26 CFR 1.1081-3 - Exchanges of stock or securities solely for stock or securities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Exchanges of stock or securities solely for stock or securities. 1.1081-3 Section 1.1081-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF... § 1.1081-3 Exchanges of stock or securities solely for stock or securities. The exchange, without the...

Management, Planning, and Monitoring Population Education Programmes. Abstract-Bibliography Series 8.

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and the Pacific.

This document abstracts and reviews 32 publications that describe population education programs developed for Asia and the Pacific region. The documents are grouped under three sections: (1) management; (2) planning; and (3) monitoring/evaluation. Section 1 consists of 12 selected titles that deal with management of population education programs.…

Software design and documentation language: User's guide for SDDL release 4

NASA Technical Reports Server (NTRS)

Zepko, T. M.

1981-01-01

The changes introduced in the PASCAL implementation of the software design and documentation language are described. These changes include a number of new capabilities, plus some changes to make the language more consistent and easier to use. Incompatibilities with earlier versions are limited to certain of the directive statements.

Tech-Prep Competency Profiles within the Engineering Technologies Cluster.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. Center on Education and Training for Employment.

This document contains 12 competency profiles for tech prep courses within the engineering technologies cluster. The document consists of the following sections: (1) systemic curriculum reform philosophy--Ohio's vision of tech prep and its six critical components; (2) an explanation of the process of developing the tech prep competencies; (3) a…

Evaluation Report: ESEA Program of Compensatory Education (Including Abstract and Appendix).

ERIC Educational Resources Information Center

Badal, Alden W.

This document is an evaluation of 1967-68 compensatory education programs in Oakland, California, funded by the Elementary and Secondary Education Act, Title I. It consists of three parts: (1) the evaluation report; (2) an appendix containing tables, questionnaire summaries, sample forms, etc.; and (3) an abstract of the total document. Reported…

Drafting and Design Technology Curriculum Guide.

ERIC Educational Resources Information Center

Idaho State Dept. of Education, Boise. Div. of Vocational Education.

This document provides lists of tasks, performance objectives, and enabling objectives for 1,800 hours of postsecondary instruction or 900 hours of secondary instruction in the drafting and design technology program. Following a list of tasks and an explanation of the program, the bulk of the document consists of 25 modules, each of which is a…

Project: Ways to Improve Education in Desegregated Schools (WIEDS). [Appendices for Final Report.

ERIC Educational Resources Information Center

Roberson, Don R.; And Others

This document consists of a literature review and the description of a field study undertaken as part of a pilot research project focusing on improving education in desegregated public schools. The review documents the organization and successful programmatic strategies of school integration. Findings are presented in terms of administrative and…

Market Analysis and Consumer Impacts Source Document. Part I. The Motor Vehicle Market in the Late 1970's

DOT National Transportation Integrated Search

1980-12-01

The source document on motor vehicle market analysis and consumer impact consists of three parts. Part I is an integrated overview of the motor vehicle market in the late 1970's, with sections on the structure of the market, motor vehicle trends, con...

32 CFR 1900.44 - Action by appeals authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... complete record of the request consisting of the request, the document(s) (sanitized and full text) at... Panel. (c) Decision by the Historical Records Policy Board. In any cases of divided vote by the ARP, any member of that body is authorized to refer the request to the CIA Historical Records Policy Board which...

32 CFR 1908.35 - Action by appeals authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... consisting of the request, the document(s) (sanitized and full text) at issue, and the findings of the... of the Panel. (b) Action by Historical Records Policy Board. In any cases of divided vote by the ARP, any member of that body is authorized to refer the request to the CIA Historical Records Policy Board...

77 FR 56251 - Aviation Rulemaking Advisory Committee (ARAC); New Task Assignment for the ARAC: Establishment of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... with the Airman Certification Standards documents; and to propose knowledge test item bank questions... ensure that knowledge test item bank questions are consistent with both the Airman Certification... knowledge and risk management into each Area of Operation in the current Practical Test Standards documents...

Career Education in Appalachian Maryland: Awareness. Elementary Supplemental Activities Level 1.

ERIC Educational Resources Information Center

Maryland State Dept. of Education, Baltimore. Div. of Vocational-Technical Education.

Career education activities for use in Grade 1 are presented in the document. Behavioral objectives for the following subject areas are provided: art, homemaking, language arts, math, music, physical education, resource people, science, social studies, and workshop abilities. The bulk of the document consists of eight units of activities focusing…

Career Education in Appalachian Maryland: Awareness. Elementary Supplemental Activities Level 5.

ERIC Educational Resources Information Center

Maryland State Dept. of Education, Baltimore. Div. of Vocational-Technical Education.

Career education activities for use in Grade 5 are presented in the document. Behavioral objectives for the following subject areas are provided: art, homemaking, language arts, math, music, physical education, resource people, science, social studies, and workshop abilities. The bulk of the document consists of six units of activities focusing on…

Career Education in Appalachian Maryland: Awareness. Elementary Supplemental Activities Level 3.

ERIC Educational Resources Information Center

Maryland State Dept. of Education, Baltimore. Div. of Vocational-Technical Education.

Career education activities for use in Grade 3 are presented in the document. Behavioral objectives for the following subject areas are provided: art, homemaking, language arts, math, music, physical education, resource people, science, social studies, and workshop abilities. The bulk of the document consists of seven units of activities focusing…

Career Education in Appalachian Maryland: Awareness. Elementary Supplemental Activities Level 2.

ERIC Educational Resources Information Center

Maryland State Dept. of Education, Baltimore. Div. of Vocational-Technical Education.

Career education activities for use in Grade 2 are presented in the document. Behavioral objectives for the following subject areas are provided: art, homemaking, language arts, math, music, physical education, resource people, science, social studies, and workshop abilities. The bulk of the document consists of nine units of activities focusing…

Career Education in Appalachian Maryland: Awareness. Elementary Supplemental Activities Level 4.

ERIC Educational Resources Information Center

Maryland State Dept. of Education, Baltimore. Div. of Vocational-Technical Education.

Career education activities for use in Grade 4 are presented in the document. Behavioral objectives for the following subject areas are provided: art, homemaking, language arts, math, music, physical education, resource people, science, social studies, and workshop abilities. The bulk of the document consists of six units of activities focusing on…

Statistics on Social Work Education in the United States: 1978.

ERIC Educational Resources Information Center

Rubin, Allen, Comp.; Whitcomb, G. Robert, Comp.

The document consists of statistical tables which characterize social work education in the United States in 1978. Data were supplied by all Council on Social Work Education accredited graduate programs and all but three undergraduate programs. Six sections comprise the document. Section I analyzes the regional distribution of 264 institutions,…

Government Acronyms and Alphabetic Designations Used in DDC.

ERIC Educational Resources Information Center

Defense Documentation Center, Alexandria, VA.

The compilation consists of a guide to acronyms and alphabetic designations used by the Department of Defense (DOD), federal government and foreign military organizations on documents to designate reports on research monitored by them and cataloged by the Defense Documentation Center (DDC). In all instances the acronyms are those actually used by…

Not Like Me: How Minority Youth Distance Themselves from Risk.

ERIC Educational Resources Information Center

Chapin, John R.

The third-person perception hypothesis posits that people believe others are more influenced by media messages than they are. The existing literature consistently documents that individuals make self versus other distinctions when assessing media effects, but not how such distinctions are made. The current study sought to document the self/other…

Global Document Delivery, User Studies, and Service Evaluation: The Gateway Experience

ERIC Educational Resources Information Center

Miller, Rush; Xu, Hong; Zou, Xiuying

2008-01-01

This study examines user and service data from 2002-2006 at the East Asian Gateway Service for Chinese and Korean Academic Journal Publications (Gateway Service), the University of Pittsburgh. Descriptive statistical analysis reveals that the Gateway Service has been consistently playing the leading role in global document delivery service as well…

NASA/Aerospace Education Services Program. Classroom Activities.

ERIC Educational Resources Information Center

Nations, Jim, Comp.

This document consists of a collection of classroom activities as they appeared in the "Aviation and Space Education News" from 1988 to 1991. The 45 activities in the document are organized in the following sections: (1) Aeronautics; (2) Earth Science; (3) Space Science; (4) Life in Space; (5) Rockets; and (6) Models. Each activity is…

Testing the Integrity of a Psychotherapy Protocol: Assessment of Adherence and Competence.

ERIC Educational Resources Information Center

Waltz, Jennifer; And Others

1993-01-01

Treatment manuals and protocols have made delivery of particular therapies purer and more consistent, initiating a demand that researchers not only use treatment manuals to improve purity of their therapy but document that their efforts to achieve purity have been successful. Strategies that have been used to document treatment integrity are…

Developing Training Exemplars for the Requisite Components of Visual Threat Detection

DTIC Science & Technology

2012-09-01

construed as an official Department of the Army position, unless so designated by other authorized documents. i REPORT DOCUMENTATION PAGE 1... Design ............................................................................................................................. 34...activities in the OE. This report presents the findings from the final research phase and consists of a discussion of the design and development of the

Retail Flower Shop Salesperson and Floral Designer. Student's Manual.

ERIC Educational Resources Information Center

South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

This document consists of the student manual for a course in retail flower shop sales and floral design for use in vocational education courses in high schools in South Carolina. The guide consists of 22 learning modules that incorporate the subject matter needed by workers in these jobs. Each learning module consists of an introduction,…

Examination of the regulatory frameworks applicable to biologic drugs (including stem cells and their progeny) in Europe, the U.S., and Australia: part I--a method of manual documentary analysis.

PubMed

Ilic, Nina; Savic, Snezana; Siegel, Evan; Atkinson, Kerry; Tasic, Ljiljana

2012-12-01

Recent development of a wide range of regulatory standards applicable to production and use of tissues, cells, and other biologics (or biologicals), as advanced therapies, indicates considerable interest in the regulation of these products. The objective of this study was to analyze and compare high-tier documents within the Australian, European, and U.S. biologic drug regulatory environments using qualitative methodology. Cohort 1 of the selected 18 high-tier regulatory documents from the European Medicines Agency (EMA), the U.S. Food and Drug Administration (FDA), and the Therapeutic Goods Administration (TGA) regulatory frameworks were subject to a manual documentary analysis. These documents were consistent with the legal requirements for manufacturing and use of biologic drugs in humans and fall into six different categories. Manual analysis included a terminology search. The occurrence, frequency, and interchangeable use of different terms and phrases were recorded in the manual documentary analysis. Despite obvious differences, manual documentary analysis revealed certain consistency in use of terminology across analyzed frameworks. Phrase search frequencies have shown less uniformity than the search of terms. Overall, the EMA framework's documents referred to "medicinal products" and "marketing authorization(s)," the FDA documents discussed "drug(s)" or "biologic(s)," and the TGA documents referred to "biological(s)." Although high-tier documents often use different terminology they share concepts and themes. Documents originating from the same source have more conjunction in their terminology although they belong to different frameworks (i.e., Good Clinical Practice requirements based on the Declaration of Helsinki, 1964). Automated (software-based) documentary analysis should be obtained for the conceptual and relational analysis.

Examination of the regulatory frameworks applicable to biologic drugs (including stem cells and their progeny) in Europe, the U.S., and Australia: part II--a method of software documentary analysis.

PubMed

Ilic, Nina; Savic, Snezana; Siegel, Evan; Atkinson, Kerry; Tasic, Ljiljana

2012-12-01

A wide range of regulatory standards applicable to production and use of tissues, cells, and other biologics (or biologicals), as advanced therapies, indicates considerable interest in the regulation of these products. The objective of this study was to analyze and compare high-tier documents within the Australian, European, and U.S. biologic drug regulatory environments using qualitative methodology. Eighteen high-tier documents from the European Medicines Agency (EMA), U.S. Food and Drug Administration (FDA), and Therapeutic Goods Administration (TGA) regulatory frameworks were subject to automated text analysis. Selected documents were consistent with the legal requirements for manufacturing and use of biologic drugs in humans and fall into six different categories. Concepts, themes, and their co-occurrence were identified and compared. The most frequent concepts in TGA, FDA, and EMA frameworks were "biological," "product," and "medicinal," respectively. This was consistent with the previous manual terminology search. Good Manufacturing Practice documents, across frameworks, identified "quality" and "appropriate" as main concepts, whereas in Good Clinical Practice (GCP) documents it was "clinical," followed by "trial," "subjects," "sponsor," and "data." GCP documents displayed considerably higher concordance between different regulatory frameworks, as demonstrated by a smaller number of concepts, similar size, and similar distance between them. Although high-tier documents often use different terminology, they share concepts and themes. This paper may be a modest contribution to the recognition of similarities and differences between analyzed regulatory documents. It may also fill the literature gap and provide some foundation for future comparative research of biologic drug regulations on a global level.

Use of Headings and Classifications by Physicians in Medical Narratives of EHRs

PubMed Central

Häyrinen, K.; Harno, K.; Nykänen, P.

2011-01-01

Objective The purpose of this study was to describe and evaluate patient care documentation by hospital physicians in EHRs and especially the use of national headings and classifications in these documentations Material and Methods The initial material consisted of a random sample of 3,481 medical narratives documented in EHRs during the period 2004-2005 in one department of a Finnish central hospital. The final material comprised a subset of 1,974 medical records with a focus on consultation requests and consultation responses by two specialist groups from 871 patients. This electronic documentation was analyzed using deductive content analyses and descriptive statistics. Results The physicians documented patient care in EHRs principally as narrative text. The medical narratives recorded by specialists were structured with headings in less than half of the patient cases. Consultation responses in general were more often structured with headings than consultation requests. The use of classifications was otherwise insignificant, but diagnoses were documented as ICD 10 codes in over 50% of consultation responses by both medical specialties. Conclusion There is an obvious need to improve the structuring of narrative text with national headings and classifications. According to the findings of this study, reason for care, patient history, health status, follow-up care plan and diagnosis are meaningful headings in physicians’ documentation. The existing list of headings needs to be analyzed within a consistent unified terminology system as a basis for further development. Adhering to headings and classifications in EHR documentation enables patient data to be shared and aggregated. The secondary use of data is expected to improve care management and quality of care. PMID:23616866

Development of electronic medical record charting for hospital-based transfusion and apheresis medicine services: Early adoption perspectives

PubMed Central

Levy, Rebecca; Pantanowitz, Liron; Cloutier, Darlene; Provencher, Jean; McGirr, Joan; Stebbins, Jennifer; Cronin, Suzanne; Wherry, Josh; Fenton, Joseph; Donelan, Eileen; Johari, Vandita; Andrzejewski, Chester

2010-01-01

Background: Electronic medical records (EMRs) provide universal access to health care information across multidisciplinary lines. In pathology departments, transfusion and apheresis medicine services (TAMS) involved in direct patient care activities produce data and documentation that typically do not enter the EMR. Taking advantage of our institution's initiative for implementation of a paperless medical record, our TAMS division set out to develop an electronic charting (e-charting) strategy within the EMR. Methods: A focus group of our hospital's transfusion committee consisting of transfusion medicine specialists, pathologists, residents, nurses, hemapheresis specialists, and information technologists was constituted and charged with the project. The group met periodically to implement e-charting TAMS workflow and produced electronic documents within the EMR (Cerner Millenium) for various service line functions. Results: The interdisciplinary working group developed and implemented electronic versions of various paper-based clinical documentation used by these services. All electronic notes collectively gather and reside within a unique Transfusion Medicine Folder tab in the EMR, available to staff with access to patient charts. E-charting eliminated illegible handwritten notes, resulted in more consistent clinical documentation among staff, and provided greater realered. However, minor updates and corrections to documents as well as select work re-designs were required for optimal use of e-charting-time review/access of hemotherapy practices. No major impediments to workflow or inefficiencies have been encount by these services. Conclusion: Documentation of pathology subspecialty activities such as TAMS can be successfully incorporated into the EMR. E-charting by staff enhances communication and helps promote standardized documentation of patient care within and across service lines. Well-constructed electronic documents in the EMR may also enhance data mining, quality improvement, and biovigilance monitoring activities. PMID:20805955

Examination of the Regulatory Frameworks Applicable to Biologic Drugs (Including Stem Cells and Their Progeny) in Europe, the U.S., and Australia: Part I—A Method of Manual Documentary Analysis

PubMed Central

Savic, Snezana; Siegel, Evan; Atkinson, Kerry; Tasic, Ljiljana

2012-01-01

Recent development of a wide range of regulatory standards applicable to production and use of tissues, cells, and other biologics (or biologicals), as advanced therapies, indicates considerable interest in the regulation of these products. The objective of this study was to analyze and compare high-tier documents within the Australian, European, and U.S. biologic drug regulatory environments using qualitative methodology. Cohort 1 of the selected 18 high-tier regulatory documents from the European Medicines Agency (EMA), the U.S. Food and Drug Administration (FDA), and the Therapeutic Goods Administration (TGA) regulatory frameworks were subject to a manual documentary analysis. These documents were consistent with the legal requirements for manufacturing and use of biologic drugs in humans and fall into six different categories. Manual analysis included a terminology search. The occurrence, frequency, and interchangeable use of different terms and phrases were recorded in the manual documentary analysis. Despite obvious differences, manual documentary analysis revealed certain consistency in use of terminology across analyzed frameworks. Phrase search frequencies have shown less uniformity than the search of terms. Overall, the EMA framework's documents referred to “medicinal products” and “marketing authorization(s),” the FDA documents discussed “drug(s)” or “biologic(s),” and the TGA documents referred to “biological(s).” Although high-tier documents often use different terminology they share concepts and themes. Documents originating from the same source have more conjunction in their terminology although they belong to different frameworks (i.e., Good Clinical Practice requirements based on the Declaration of Helsinki, 1964). Automated (software-based) documentary analysis should be obtained for the conceptual and relational analysis. PMID:23283551

Arc/Forearc Lengthening at Plate Triple Junctions and the Formation of Ophiolitic Soles

NASA Astrophysics Data System (ADS)

Casey, John; Dewey, John

2013-04-01

The principal enigma of large obducted ophiolite slabs is that they clearly must have been generated by some form of organized sea-floor spreading/plate-accretion, such as may be envisioned for the oceanic ridges, yet the volcanics commonly have arc affinity (Miyashiro) with boninites (high-temperature/low-pressure, high Mg and Si andesites), which are suggestive of a forearc origin. PT conditions under which boninites and metamorphic soles form and observations of modern forearc systems lead us to the conclusion that ophiolite formation is associated with overidding plate spreading centers that intersect the trench to form ridge-trench-trench of ridge-trench-tranform triple junctions. The spreading centers extend and lengthen the forearc parallel to the trench and by definition are in supra-subduction zone (SSZ) settings. Many ophiolites likewise have complexly-deformed associated mafic-ultramafic assemblages that suggest fracture zone/transform t along their frontal edges, which in turn has led to models involving the nucleation of subduction zones on fracture zones or transpressional transforms. Hitherto, arc-related sea-floor-spreading has been considered to be either pre-arc (fore-arc boninites) or post-arc (classic Karig-style back arc basins that trench-parallell split arcs). Syn-arc boninites and forearc oceanic spreading centers that involve a stable ridge/trench/trench triple or a ridge-trench-transform triple junction, the ridge being between the two upper plates, are consistent with large slab ophiolite formation in a readied obduction settting. The direction of subduction must be oblique with a different sense in the two subduction zones and the oblique subduction cannot be partitioned into trench orthogonal and parallel strike-slip components. As the ridge spreads, new oceanic lithosphere is created within the forearc, the arc and fore-arc lengthen significantly, and a syn-arc ophiolite forearc complex is generated by this mechanism. The ophiolite ages along arc-strike; a distinctive diachronous MORB-like to boninitic to arc volcanic stratigraphy develops vertically in the forearc and eruption centers progressively migrate from the forearc back to the main arc massif with time. Dikes in the ophiolite are highly oblique to the trench (as are back-arc magnetic anomalies. Boninites and high-mg andesites are generated in the fore-arc under the aqueous, low pressure/high temperature, regime at the ridge above the instantaneously developed subducting and dehydrating slab. Subducted slab refrigeration of the hanging wall ensues and accretion of MORB metabasites to the hanging wall of the subduction channel initiates. Mafic protolith garnet/two pyroxene granulites to greenschists accrete and form the inverted P and T metamorphic sole prior to obduction. Sole accretion of lithosphere begins at about 1000°C and the full retrogressive sole may be fully formed within ten to fifteen million years of accretion, at which time low grade subduction melanges accrete. Obduction of the SSZ forearc ophiolite with its subjacent metamorphic sole occurs whenever the oceanic arc attempts subduction of a stable buoyant continental or back arc margin.

An investigation of reports of Controlled Flight Toward Terrain (CFTT)

NASA Technical Reports Server (NTRS)

Porter, R. F.; Loomis, J. P.

1981-01-01

Some 258 reports from more than 23,000 documents in the files of the Aviation Safety Reporting System (ASRS) were found to be to the hazard of flight into terrain with no prior awareness by the crew of impending disaster. Examination of the reports indicate that human error was a casual factor in 64% of the incidents in which some threat of terrain conflict was experienced. Approximately two-thirds of the human errors were attributed to controllers, the most common discrepancy being a radar vector below the Minimum Vector Altitude (MVA). Errors by pilots were of a much diverse nature and include a few instances of gross deviations from their assigned altitudes. The ground proximity warning system and the minimum safe altitude warning equipment were the initial recovery factor in some 18 serious incidents and were apparently the sole warning in six reported instances which otherwise would most probably have ended in disaster.

[Limitations on Therapeutic Efforts: Much More than not Doing].

PubMed

Bernal, Diana Restrepo; Uribe, Clara Cossio

2013-03-01

The term LTE (Limitations on Therapeutic Efforts) refers to the withholding or withdrawing of medical treatment to a patient (either with or without capacity to decide) who does not clinically benefit from it. Although some countries already have legislation and official documents to formalize it, there are several reasons limiting the dissemination and acceptance of this proposal. One is the fact that physicians and health institutions consider this issue as the sole responsibility of patients; another reason is that physicians and the community in general believe the discussion refers just to elderly and terminal patients. It is necessary an academic approach on LTE from both, physicians and the community in general, to promote a sound ethical reflection so as to assist patients and their relatives in the hard task of becoming autonomous to decide and plan their futures. Copyright © 2013 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

Validity of Self-reported Sexual Behavior Among Adolescents: Where Do We Go from Here?

PubMed

DiClemente, Ralph J

2016-01-01

Adolescents have high rates of sexually transmitted infections (STIs). Adolescents consuming alcohol and using drugs have markedly greater HIV/STI risk and are a priority population for intervention. Accurate measurement of sexual risk behavior is critical for understanding individual's risk for HIV/STI, transmission dynamics of HIV/STI, and evaluating the efficacy of interventions designed reduce HIV/STI risk. However, significant challenges to accurately measuring adolescents' self-reported sexual behavior are well-documented. Recent advances in microbiology, such as the use of less invasive specimen collection for DNA assays, can assist researchers in more accurately measuring adolescents' sexual risk behavior. However, the majority of studies of adolescents' sexual risk rely solely on self-reported behavior; therefore, methods to improve the validity of adolescents' self-reported sexual behavior are needed. In addition, integrating biologic measures to complement self-reported measures are recommended, when appropriate and feasible.

Native American prehistory of the middle Savannah River Valley. A synthesis of archaeological investigations on the Savannah River Site, Aiken and Barnwell Counties, South Carolina

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sassaman, K.E.; Brooks, M.J.; Hanson, G.T.

1990-12-31

Archaeological investigations on the United States Department of Energy`s (DOE) Savannah River Site (SRS) in South Carolina span 17 years and continue today through a cooperative agreement between DOE and the South Carolina Institute of Archaeology and Anthropology (SCIAA), University of South Carolina. The Savannah River Archaeological Research Program (SRARP) of SCIAA has been and continues to be the sole archaeological consultant for DOE-SRS. This report documents technical aspects of all prehistoric archaeological research conducted by the SRARP between 1973 and 1987. Further, this report provides interpretative contexts for archaeological resources as a basis for an archaeological resource plan reportedmore » elsewhere (SRARP 1989), and as a comprehensive statement of our current understanding of Native American prehistory. 400 refs., 130 figs., 39 tabs.« less

Reflexive Research Ethics in Fetal Tissue Xenotransplantation Research

PubMed Central

Panikkar, Bindu; Smith, Natasha; Brown, Phil

2013-01-01

For biomedical research in which the only involvement of the human subject is the provision of tissue or organ samples, a blanket consent, i.e. consent to use the tissue for anything researchers wish to do, is considered by many to be adequate for legal and IRB requirements. Alternatively, a detailed informed consent provides patients or study participants with more thorough information about the research topic. We document here the beliefs and opinions of the research staff on informed consent and the discussion-based reflexive research ethics process that we employed in our fetal tissue xenotransplantion research on the impact of environmental exposures on fetal development. Reflexive research ethics entails the continued adjustment of research practice according to relational and reflexive understandings of what might be beneficent or harmful. Such reflexivity is not solely an individual endeavor, but rather a collective relationship between all actors in the research process. PMID:23074992

The County Council of the Order of Physicians in Ille et Vilaine (France) during the Second World War.

PubMed

Gentili, Marc E

2013-06-01

Initially, the examination of the archives from the Ille et Vilaine Council of the College of Physicians was based solely on the findings of Dr. George from Rennes who had helped Jews during the Occupation. Gradually I perceived that the quality of available documents permitted writing this article to show a contrasting view of this dark period in our history. This work aimed to analyze the role of the County Council (CC) of Ille et Vilaine through minutes of their meetings and to compare, year by year, directives and circulars from the Supreme Council of the Order of Physicians (SCO) sent to CC at this period. We will observe see that between the institution, acting by strictly following the orders from the "French State", and the county councils, for some at least, there was a gap that men of good will knew not to cross.

A preliminary assessment of the deep-sea Decapoda collected during the KARUBENTHOS 2015 Expedition to Guadeloupe Island.

PubMed

Poupin, Joseph; Corbari, Laure

2016-11-13

A preliminary assessment of the deep-sea Decapoda is proposed for Guadeloupe Island based solely on high definition macro photographs taken during the KARUBENTHOS 2015 Expedition to the Island (R/V Antea, 7-29 June 2015). Overall, 190 species are recognized, several of which are depicted with their fresh color for the first time. Previous records in the Lesser Antilles are documented and the geographic distribution of the species in these Islands is given. The historical contribution of the steamer Blake (1878-1879) in the Lesser Antilles is emphasized. All species inventoried during KARUBENTHOS 2015 were already reported in the western Atlantic but 34 of them are new records for the Lesser Antilles and 116 are reported for the first time from Guadeloupe Island. This preliminary inventory is estimated to include about 38% of the deep-sea Decapoda potentially occurring around Guadeloupe Island.

Water consumption in Iron Age, Roman, and Early Medieval Croatia.

PubMed

Lightfoot, E; Slaus, M; O'Connell, T C

2014-08-01

Patterns of water consumption by past human populations are rarely considered, yet drinking behavior is socially mediated and access to water sources is often socially controlled. Oxygen isotope analysis of archeological human remains is commonly used to identify migrants in the archeological record, but it can also be used to consider water itself, as this technique documents water consumption rather than migration directly. Here, we report an oxygen isotope study of humans and animals from coastal regions of Croatia in the Iron Age, Roman, and Early Medieval periods. The results show that while faunal values have little diachronic variation, the human data vary through time, and there are wide ranges of values within each period. Our interpretation is that this is not solely a result of mobility, but that human behavior can and did lead to human oxygen isotope ratios that are different from that expected from consumption of local precipitation. © 2014 Wiley Periodicals, Inc.

Congenital Partial Absence of Trapezius with Variant Pattern of Rectus Sheath.

PubMed

Tigga, Sarika Rachel; Goswami, Preeti; Khanna, Jugesh

2016-04-01

Musculocutaneous pedicled/free flaps are an essential prerequisite for reconstructive surgery. Amongst the trunk muscles commonly harvested for flaps, the trapezius and rectus abdominis provide satisfactory coverage for cranial and trunk defects. unilateral/bilateral or partial congenital absence of trapezius muscle is well documented and may result in muscular imbalances compromising posture and limb movements. During routine cadaveric dissection, we encountered a case of bilateral partial absence of occipital part of the trapezius muscle. Concurrently, the ventral abdominal musculature displayed the aponeurosis of transversus abdominis muscle solely forming the posterior wall of the rectus sheath. These conjointly occurring anomalies advocate a compensatory strengthening of the anterior wall of rectus sheath in response to the congenital absence of occipital part of the trapezius, probably to counteract the postural instability. The present study focuses on recognition of compensatory mechanisms resulting from congenital variations as identification of such processes may prevent chronic debilitating conditions.

Selections that isolate recombinant mitochondrial genomes in animals

PubMed Central

Ma, Hansong; O'Farrell, Patrick H

2015-01-01

Homologous recombination is widespread and catalyzes evolution. Nonetheless, its existence in animal mitochondrial DNA is questioned. We designed selections for recombination between co-resident mitochondrial genomes in various heteroplasmic Drosophila lines. In four experimental settings, recombinant genomes became the sole or dominant genome in the progeny. Thus, selection uncovers occurrence of homologous recombination in Drosophila mtDNA and documents its functional benefit. Double-strand breaks enhanced recombination in the germline and revealed somatic recombination. When the recombination partner was a diverged Drosophila melanogaster genome or a genome from a different species such as Drosophila yakuba, sequencing revealed long continuous stretches of exchange. In addition, the distribution of sequence polymorphisms in recombinants allowed us to map a selected trait to a particular region in the Drosophila mitochondrial genome. Thus, recombination can be harnessed to dissect function and evolution of mitochondrial genome. DOI: http://dx.doi.org/10.7554/eLife.07247.001 PMID:26237110

Infant toxicology: state of the science and considerations in evaluation of safety.

PubMed

Neal-Kluever, April; Aungst, Jason; Gu, Yan; Hatwell, Karen; Muldoon-Jacobs, Kristi; Liem, Ayesha; Ogungbesan, Adejoke; Shackelford, Mary

2014-08-01

Differences in the physiology and biological susceptibilities of adults and infants have led to growing interest in safety evaluation methods for exposures from infant formula packaging. In addition to potential physiological differences, infants aged 0-6 months may consume a sole source of food, infant formula or breast milk, and consume higher amounts of food relative to body weight compared to adults. While the duration of the exposure is short compared to the expected lifespan of the individual, it occurs during a period of important developmental processes. The purpose of this document is to (1) review key biological and exposure elements that may impact the evaluation of safety for food contact products intended for use by infants, (2) summarize the current reproductive and developmental toxicity testing protocols available, and (3) identify potential data gaps concerning this period of development. Published by Elsevier Ltd.

Statistical Tools for Designing Initial and Post-Removal UXO Characterization Surveys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pulsipher, Brent A.; Gilbert, Richard O.; Wilson, John E.

2002-09-06

The Department of Defense (DoD) is in the process of assessing and remediating closed, transferred, and transferring ranges. It is estimated that over 20 million acres of land in the United States potentially contain UXO. The release of DoD sites for public use will require high confidence that UXO is not present. This high confidence may be achieved solely from an extensive knowledge of historical site operations as documented in the conceptual site model or in combination with geophysical sensor surveys designed to have a sufficiently high probability of finding UXO contaminated zones. Many of these sites involve very largemore » geographical areas such that it is often impractical and/or cost prohibitive to perform 100% surveys of the entire site of interest. In that case, it is necessary to be explicit about the performance required of a survey that covers less than 100% of the site.« less

Virulence properties of cariogenic bacteria

PubMed Central

Kuramitsu, Howard K; Wang, Bing-Yan

2006-01-01

The importance of Streptococcus mutans in the etiology of dental caries has been well documented. However, there is growing recognition that the cariogenic potential of dental plaque may be determined by the composite interactions of the total plaque bacteria rather than solely the virulence properties of a single organism. This study will examine how the interactions of S. mutans with other biofilm constituents may influence the cariogenicity of plaque samples. In order to begin to investigate the effects of nonmutans streptococci on the cariogenic potential of S. mutans, we have examined the effects of Streptococcus gordonii on the virulence properties of the former organisms. These studies have indicated that S.gordonii can attenuate several potential virulence properties of S. mutans including bacteriocin production, genetic transformation, and biofilm formation. Therefore, modulation of the interactions between plaque bacteria might be a novel approach for attenuating dental caries initiation. PMID:16934112

Cemento-osseous dysplasia in Jamaica: review of six cases.

PubMed

Ogunsalu, C; Miles, D

2005-09-01

Six cases of cemento-osseous dysplasia (COD) of the jaw bone in Jamaicans are reviewed. Five were documented over a 15-year period (1980-1995). These include a case of florid cemento-osseous dysplasia (previously called gigantiform cementoma). Three of the initial cases were histologically diagnosed as gigantiform cementoma. There was no indication in the patient's case file whether these were familial or non-familial. The other two cases were diagnosed histologically as periapical cemento-osseous dysplasia and cementoblastoma respectively. Based on the current understanding of the nature of florid-cemento-osseous dysplasia (FLCOD), a new case was diagnosed as such solely on radiological findings. This single case of FLCOD is reported and discussed against the background of other cemento-osseous lesions. Special emphasis is placed on the radiology of COD in this paper. The confirmative role of radiology without the need for histophathology and treatment for asymptomatic FLCOD is emphasized.

Corporate influence on threshold limit values.

PubMed

Castleman, B I; Ziem, G E

1988-01-01

Investigations into the historical development of specific Threshold Limit Values (TLVs) for many substances have revealed serious shortcomings in the process followed by the American Conference of Governmental Industrial Hygienists. Unpublished corporate communications were important in developing TLVs for 104 substances; for 15 of these, the TLV documentation was based solely on such information. Efforts to obtain written copies of this unpublished material were mostly unsuccessful. Case studies on the TLV Committee's handling of lead and seven carcinogens illustrate various aspects of corporate influence and interaction with the committee. Corporate representatives listed officially as "consultants" since 1970 were given primary responsibility for developing TLVs on proprietary chemicals of the companies that employed them (Dow, DuPont). It is concluded that an ongoing international effort is needed to develop scientifically based guidelines to replace the TLVs in a climate of openness and without manipulation by vested interests.

Sequential Probability Ratio Test for Spacecraft Collision Avoidance Maneuver Decisions

NASA Technical Reports Server (NTRS)

Carpenter, J. Russell; Markley, F. Landis

2013-01-01

A document discusses sequential probability ratio tests that explicitly allow decision-makers to incorporate false alarm and missed detection risks, and are potentially less sensitive to modeling errors than a procedure that relies solely on a probability of collision threshold. Recent work on constrained Kalman filtering has suggested an approach to formulating such a test for collision avoidance maneuver decisions: a filter bank with two norm-inequality-constrained epoch-state extended Kalman filters. One filter models the null hypotheses that the miss distance is inside the combined hard body radius at the predicted time of closest approach, and one filter models the alternative hypothesis. The epoch-state filter developed for this method explicitly accounts for any process noise present in the system. The method appears to work well using a realistic example based on an upcoming, highly elliptical orbit formation flying mission.

From Index Catalogue to Gopher space: changes in our profession as reflected in the Handbook and CPHSL.

PubMed Central

Bunting, A

1994-01-01

A fifty-year review of the history of health sciences librarianship, as reflected in four editions of the Handbook of Medical Library Practice and its successor, Current Practice in Health Sciences Librarianship, illustrates the significant changes our profession has undergone. Publication in 1943 of the first edition of the Handbook marked an important milestone in the development of the Medical Library Association, as a group of dedicated volunteers documented standard practice and recorded useful data. Administration of health sciences libraries has moved from art to science. Responsibility for the development of collections is now the sole purview of professional librarians. Automation and bibliographic standards have revolutionized the methods for controlling and providing access to information resources. And, the means by which assistance is provided to library users, through the use of computer and telecommunications technology, has changed dramatically. PMID:8136754

Do Modern Spectacles Endanger Surgeons?

PubMed Central

Chong, Simon J.; Smith, Charlotte; Bialostocki, Adam; McEwan, Christopher N.

2007-01-01

Background: Despite documented cases of infectious disease transmission to medical staff via conjunctival contamination and widespread recommendation of protective eyewear use during surgical procedures, a large number of surgeons rely on their prescription spectacles as sole eye protection. Modern fashion spectacles, being of increasingly slim design, may no longer be adequate in this role. Methods: A survey was conducted among the surgeons at Waikato Hospital from December 7, 2004 to February 1, 2005, to assess current operating theater eyewear practices and attitudes. Those who wore prescription spectacles were asked to assume a standardized “operating position” from which anatomic measurements were obtained. These data were mathematically analyzed to determine the degree of palebral fissure protection conferred by their spectacles. Results: Of 71 surgical practitioners surveyed, 45.1% required prescription lenses for operating, the mean spectacle age being 2.45 years; 84.5% had experienced prior periorbital blood splashes; 2.8% had previously contracted an illness attributed to such an event; 78.8% participants routinely used eye protection, but of the 27 requiring spectacles, 68.0% used these as their sole eye protection. Chief complaints about safety glasses and facial shields were of fogging, poor comfort, inability to wear spectacles underneath, and unavailability. Our model predicted that 100%, 92.6%, 77.8%, and 0% of our population were protected by their spectacles laterally, medially, inferiorly, and superiorly, respectively. Conclusions: Prescription spectacles of contemporary styling do not provide adequate protection against conjunctival blood splash injuries. Our model predicts the design adequacy of currently available purpose-designed protective eyewear, which should be used routinely. PMID:17435558

Do modern spectacles endanger surgeons? The Waikato Eye Protection Study.

PubMed

Chong, Simon J; Smith, Charlotte; Bialostocki, Adam; McEwan, Christopher N

2007-03-01

Despite documented cases of infectious disease transmission to medical staff via conjunctival contamination and widespread recommendation of protective eyewear use during surgical procedures, a large number of surgeons rely on their prescription spectacles as sole eye protection. Modern fashion spectacles, being of increasingly slim design, may no longer be adequate in this role. A survey was conducted among the surgeons at Waikato Hospital from December 7, 2004 to February 1, 2005, to assess current operating theater eyewear practices and attitudes. Those who wore prescription spectacles were asked to assume a standardized "operating position" from which anatomic measurements were obtained. These data were mathematically analyzed to determine the degree of palebral fissure protection conferred by their spectacles. Of 71 surgical practitioners surveyed, 45.1% required prescription lenses for operating, the mean spectacle age being 2.45 years; 84.5% had experienced prior periorbital blood splashes; 2.8% had previously contracted an illness attributed to such an event; 78.8% participants routinely used eye protection, but of the 27 requiring spectacles, 68.0% used these as their sole eye protection. Chief complaints about safety glasses and facial shields were of fogging, poor comfort, inability to wear spectacles underneath, and unavailability. Our model predicted that 100%, 92.6%, 77.8%, and 0% of our population were protected by their spectacles laterally, medially, inferiorly, and superiorly, respectively. Prescription spectacles of contemporary styling do not provide adequate protection against conjunctival blood splash injuries. Our model predicts the design adequacy of currently available purpose-designed protective eyewear, which should be used routinely.

Selective skin sensitivity changes and sensory reweighting following short-duration space flight.

PubMed

Lowrey, Catherine R; Perry, Stephen D; Strzalkowski, Nicholas D J; Williams, David R; Wood, Scott J; Bent, Leah R

2014-03-15

Skin sensory input from the foot soles is coupled with vestibular input to facilitate body orientation in a gravitational environment. Anecdotal observations suggest that foot sole skin becomes hypersensitive following space flight. The veritable level of skin sensitivity and its impact on postural disequilibrium observed post space flight have not been documented. Skin sensitivity of astronauts (n = 11) was measured as vibration perception at the great toe, fifth metatarsal and heel. Frequencies targeted four classes of receptors: 3 and 25 Hz for slow-adapting (SA) receptors and 60 and 250 Hz for fast-adapting (FA) receptors. Data were collected pre- and post-space flight. We hypothesized that skin sensitivity would increase post-space flight and correlate to balance measures. Decreased skin sensitivity was found on landing day at 3 and 25 Hz on the great toe. Hypersensitivity was found for a subset of astronauts (n = 6) with significantly increased sensitivity to 250 Hz at the heel. This subset displayed a greater reduction in computerized dynamic posturography (CDP) equilibrium (EQ) scores (-54%) on landing vs. non-hypersensitive participants (-11%). Observed hyposensitivity of SA (pressure) receptors may indicate a strategy to reduce pressure input during periods of unloading. Hypersensitivity of FAs coupled with reduced EQ scores may reflect targeted sensory reweighting. Altered gravito-inertial environments reduce vestibular function in balance control which may trigger increased weighting of FAs (that signal foot contact, slips). Understanding modulations to skin sensitivity has translational implications for mitigating postural disequilibrium following space flight and for on-Earth preventative strategies for imbalance in older adults.

A locally initiated and executed measles outbreak response immunization campaign in the nylon health district, Douala Cameroon 2011.

PubMed

Sume, Gerald Etapelong; Fouda, André Arsène Bita; Kobela, Marie; Nguelé, Salomé; Emah, Irène; Atem, Peter

2013-03-16

The Cameroon health system is divided into central, intermediate and peripheral levels. Of the 43 health districts with a measles outbreak in Cameroon in 2011, only the Nylon Health District organized a documented outbreak response immunization. We present the methods and results of the response campaign solely shouldered by the district and intermediate level. The risk group, targets and neighborhoods to be vaccinated were identified after a detailed analysis of initial cases. The intermediate level defined strategies, provided logistics, capacity building and 41% of the operational budget while 59% was completed by the peripheral level. Microsoft Office Excel 2007 was used to estimate coverage rates and to draw an epidemic curve. The response immunization campaign was organized on the 14th epidemiological week, 10 weeks after the onset of the outbreak which ended 11 weeks thereafter. A total of 15867(108.5%) children aged 9-59 months were vaccinated in five health areas at a direct cost (vaccines excluded) of 71.34FCFA ($0.143) per vaccinated child. An additional 824 children aged 9-59 months were vaccinated around the residence of notified cases in neighborhoods which were not involved in the response campaign. The number of cases after the response campaign was lower than before. Once vaccines are available, prompt outbreak response campaigns can be organized at operational level to obtain commendable results instead of depending solely on international organizations or central levels. Decision makers at the intermediate and operational levels should redeploy available funds during emergencies to prevent the development of extreme public health conditions.

Deletion of the Saccharomyces cerevisiae ARO8 gene, encoding an aromatic amino acid transaminase, enhances phenylethanol production from glucose.

PubMed

Romagnoli, Gabriele; Knijnenburg, Theo A; Liti, Gianni; Louis, Edward J; Pronk, Jack T; Daran, Jean-Marc

2015-01-01

Phenylethanol has a characteristic rose-like aroma that makes it a popular ingredient in foods, beverages and cosmetics. Microbial production of phenylethanol currently relies on whole-cell bioconversion of phenylalanine with yeasts that harbour an Ehrlich pathway for phenylalanine catabolism. Complete biosynthesis of phenylethanol from a cheap carbon source, such as glucose, provides an economically attractive alternative for phenylalanine bioconversion. In this study, synthetic genetic array (SGA) screening was applied to identify genes involved in regulation of phenylethanol synthesis in Saccharomyces cerevisiae. The screen focused on transcriptional regulation of ARO10, which encodes the major decarboxylase involved in conversion of phenylpyruvate to phenylethanol. A deletion in ARO8, which encodes an aromatic amino acid transaminase, was found to underlie the transcriptional upregulation of ARO10 during growth, with ammonium sulphate as the sole nitrogen source. Physiological characterization revealed that the aro8Δ mutation led to substantial changes in the absolute and relative intracellular concentrations of amino acids. Moreover, deletion of ARO8 led to de novo production of phenylethanol during growth on a glucose synthetic medium with ammonium as the sole nitrogen source. The aro8Δ mutation also stimulated phenylethanol production when combined with other, previously documented, mutations that deregulate aromatic amino acid biosynthesis in S. cerevisiae. The resulting engineered S. cerevisiae strain produced >3 mm phenylethanol from glucose during growth on a simple synthetic medium. The strong impact of a transaminase deletion on intracellular amino acid concentrations opens new possibilities for yeast-based production of amino acid-derived products. Copyright © 2014 John Wiley & Sons, Ltd.

Sodium butyrate attenuates soybean oil-based lipid emulsion-induced increase in intestinal permeability of lipopolysaccharide by modulation of P-glycoprotein in Caco-2 cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yan, Jun-Kai; Gong, Zi-Zhen; Zhang, Tian

Down-regulation of intestinal P-glycoprotein (P-gp) by soybean oil-based lipid emulsion (SOLE) may cause elevated intestinal permeability of lipopolysaccharide (LPS) in patients with total parenteral nutrition, but the appropriate preventative treatment is currently limited. Recently, sodium butyrate (NaBut) has been demonstrated to regulate the expression of P-gp. Therefore, this study aimed to address whether treatment with NaBut could attenuate SOLE-induced increase in intestinal permeability of LPS by modulation of P-gp in vitro. Caco-2 cells were exposed to SOLE with or without NaBut. SOLE-induced down-regulation of P-gp was significantly attenuated by co-incubation with NaBut. Nuclear recruitment of FOXO 3a in response to NaButmore » was involved in P-gp regulation. Transport studies revealed that SOLE-induced increase in permeability of LPS was significantly attenuated by co-incubation with NaBut. Collectively, our results suggested that NaBut may be a potentially useful medication to prevent SOLE-induced increase in intestinal permeability of LPS. - Highlights: • Caco-2 cells were used as models for studying parenteral nutrition in vitro. • NaBut restored SOLE-induced down-regulation of P-gp in Caco-2 cells. • Regulation of P-gp by NaBut was mediated via nuclear recruitment of FOXO 3a. • NaBut modulated the permeability of LPS by P-gp function, not barrier function.« less

Effects of shoe sole hardness on plantar pressure and comfort in older people with forefoot pain.

PubMed

Lane, Tamara J; Landorf, Karl B; Bonanno, Daniel R; Raspovic, Anita; Menz, Hylton B

2014-01-01

Plantar forefoot pain is common in older people and is related to increased peak pressures under the foot during gait. Variations in the hardness of the shoe sole may therefore influence both the magnitude of loading under the foot and the perceived comfort of the shoe in this population. The aim of this investigation was to determine the effect of varying shoe sole hardness on plantar pressures and comfort in older people with forefoot pain. In-shoe plantar pressures under the forefoot, midfoot and rearfoot were recorded from 35 older people (mean age 73.2, SD 4.5 years) with current or previous forefoot pain using the pedar-X(®) system. Participants walked at their normal comfortable speed along an 8m walkway in shoes with three different levels of sole hardness: soft (Shore A25), medium (Shore A40) and hard (Shore A58). Shoe comfort was measured on a 100mm visual analogue scale. There were statistically significant differences in peak pressure of between 5% and 23% across the forefoot, midfoot and rearfoot (p<0.01). The hard-soled shoe registered the highest peak pressures and the soft-soled shoe the lowest peak pressures. However, no differences in comfort scores across the three shoe conditions were observed. These findings demonstrate that as shoe sole hardness increases, plantar pressure increases, however this does not appear to have a significant effect on shoe comfort. Crown Copyright © 2013. Published by Elsevier B.V. All rights reserved.

Do published studies of educational outreach provide documentation of potentially important characteristics?

PubMed

Van Hoof, Thomas J; Miller, Nicole E; Meehan, Thomas P

2013-01-01

Educational outreach is a common intervention used to translate research findings into practice; however, the intervention has a mixed effect on changing clinician behavior and improving patient outcomes. Based on a published set of characteristics aimed at standardizing the approach to educational outreach, the authors undertook a careful review of the literature to determine the consistency and completeness of documentation. Using a 25-item abstraction tool, the authors reviewed 68 published studies of a recent Cochrane meta-analysis to determine the extent to which educational outreach studies provide recommended documentation of important characteristics. The results indicate that studies are generally inconsistent (documentation range of 0% to 100% across characteristics) and incomplete (documentation average of 43.1% across studies) in their descriptions. Documentation shortcomings of educational outreach studies make understanding the intervention and interpreting its findings particularly challenging. The authors recommend the creation of a guideline to help improve documentation of educational outreach efforts.

E-nursing documentation as a tool for quality assurance.

PubMed

Rajkovic, Vladislav; Sustersic, Olga; Rajkovic, Uros

2006-01-01

The article presents the results of a project with which we describe the reengineering of nursing documentation. Documentation in nursing is an efficient tool for ensuring quality health care and consequently quality patient treatment along the whole clinical path. We have taken into account the nursing process and patient treatment based on Henderson theoretical model of nursing that consists of 14 basic living activities. The model of new documentation enables tracing, transparency, selectivity, monitoring and analyses. All these factors lead to improvements of a health system as well as to improved safety of patients and members of nursing teams. Thus the documentation was developed for three health care segments: secondary and tertiary level, dispensaries and community health care. The new quality introduced to the documentation process by information and communication technology is presented by a database model and a software prototype for managing documentation.

Visual Stimuli Induce Waves of Electrical Activity in Turtle Cortex

NASA Astrophysics Data System (ADS)

Prechtl, J. C.; Cohen, L. B.; Pesaran, B.; Mitra, P. P.; Kleinfeld, D.

1997-07-01

The computations involved in the processing of a visual scene invariably involve the interactions among neurons throughout all of visual cortex. One hypothesis is that the timing of neuronal activity, as well as the amplitude of activity, provides a means to encode features of objects. The experimental data from studies on cat [Gray, C. M., Konig, P., Engel, A. K. & Singer, W. (1989) Nature (London) 338, 334-337] support a view in which only synchronous (no phase lags) activity carries information about the visual scene. In contrast, theoretical studies suggest, on the one hand, the utility of multiple phases within a population of neurons as a means to encode independent visual features and, on the other hand, the likely existence of timing differences solely on the basis of network dynamics. Here we use widefield imaging in conjunction with voltage-sensitive dyes to record electrical activity from the virtually intact, unanesthetized turtle brain. Our data consist of single-trial measurements. We analyze our data in the frequency domain to isolate coherent events that lie in different frequency bands. Low frequency oscillations (<5 Hz) are seen in both ongoing activity and activity induced by visual stimuli. These oscillations propagate parallel to the afferent input. Higher frequency activity, with spectral peaks near 10 and 20 Hz, is seen solely in response to stimulation. This activity consists of plane waves and spiral-like waves, as well as more complex patterns. The plane waves have an average phase gradient of ≈ π /2 radians/mm and propagate orthogonally to the low frequency waves. Our results show that large-scale differences in neuronal timing are present and persistent during visual processing.

Visual stimuli induce waves of electrical activity in turtle cortex

PubMed Central

Prechtl, J. C.; Cohen, L. B.; Pesaran, B.; Mitra, P. P.; Kleinfeld, D.

1997-01-01

The computations involved in the processing of a visual scene invariably involve the interactions among neurons throughout all of visual cortex. One hypothesis is that the timing of neuronal activity, as well as the amplitude of activity, provides a means to encode features of objects. The experimental data from studies on cat [Gray, C. M., Konig, P., Engel, A. K. & Singer, W. (1989) Nature (London) 338, 334–337] support a view in which only synchronous (no phase lags) activity carries information about the visual scene. In contrast, theoretical studies suggest, on the one hand, the utility of multiple phases within a population of neurons as a means to encode independent visual features and, on the other hand, the likely existence of timing differences solely on the basis of network dynamics. Here we use widefield imaging in conjunction with voltage-sensitive dyes to record electrical activity from the virtually intact, unanesthetized turtle brain. Our data consist of single-trial measurements. We analyze our data in the frequency domain to isolate coherent events that lie in different frequency bands. Low frequency oscillations (<5 Hz) are seen in both ongoing activity and activity induced by visual stimuli. These oscillations propagate parallel to the afferent input. Higher frequency activity, with spectral peaks near 10 and 20 Hz, is seen solely in response to stimulation. This activity consists of plane waves and spiral-like waves, as well as more complex patterns. The plane waves have an average phase gradient of ≈π/2 radians/mm and propagate orthogonally to the low frequency waves. Our results show that large-scale differences in neuronal timing are present and persistent during visual processing. PMID:9207142

Documentation of penicillin adverse drug reactions in electronic health records: inconsistent use of allergy and intolerance labels.

PubMed

Inglis, Joshua M; Caughey, Gillian E; Smith, William; Shakib, Sepehr

2017-11-01

The majority of patients with penicillin allergy labels tolerate penicillins. Inappropriate avoidance of penicillin is associated with increased hospitalisation, infections and healthcare costs. To examine the documentation of penicillin adverse drug reactions (ADR) in a large-scale hospital-based electronic health record. Penicillin ADR were extracted from 96 708 patient records in the Enterprise Patient Administration System in South Australia. Expert criteria were used to determine consistency of ADR entry and suitability for further evaluation. Of 43 011 unique ADR reports, there were 5023 ADR to penicillins with most being entered as allergy (n = 4773, 95.0%) rather than intolerance (n = 250, 5.0%). A significant proportion did not include a reaction description (n = 1052, 20.9%). Using pre-set criteria, 10.1% of reports entered as allergy had a reaction description that was consistent with intolerance and 31.0% of the entered intolerances had descriptions consistent with allergy. Virtually all ADR (n = 4979, 99.1%) were appropriate for further evaluation by history taking or immunological testing and half (50.7%, n = 2549) had documented reactions suggesting low-risk of penicillin allergy. The frequency of penicillin allergy label in this data set is consistent with the known overdiagnosis of penicillin allergy in the hospital population. ADR documentation was poor with incomplete entries and inconsistent categorisation. The concepts of allergy and intolerance for ADR classification, whilst mechanistically valid, may not be useful at the point of ADR entry by generalist clinicians. Systematic evaluation of reported ADR is needed to improve the quality of information for future prescribers. © 2017 Royal Australasian College of Physicians.

Cold Vacuum Drying facility civil structural system design description (SYS 06)

DOE Office of Scientific and Technical Information (OSTI.GOV)

PITKOFF, C.C.

This document describes the Cold Vacuum Drying (CVD) Facility civil - structural system. This system consists of the facility structure, including the administrative and process areas. The system's primary purpose is to provide for a facility to house the CVD process and personnel and to provide a tertiary level of containment. The document provides a description of the facility and demonstrates how the design meets the various requirements imposed by the safety analysis report and the design requirements document.

Paleomagnetic Constraints From the Baoshan Area on the Deformation of the Qiangtang-Sibumasu Terrane Around the Eastern Himalayan Syntaxis

NASA Astrophysics Data System (ADS)

Li, Shihu; van Hinsbergen, Douwe J. J.; Deng, Chenglong; Advokaat, Eldert L.; Zhu, Rixiang

2018-02-01

The Sibumasu Block in SE Asia represents the eastward continuation of the Qiangtang Block. Here we report a detailed rock magnetic and paleomagnetic study on the Middle Jurassic and Paleocene rocks from northern Sibumasu, to document the crustal deformation during the India-Asia collision since the Paleocene and reconstruct the overall strike of the Qiangtang/Sibumasu elements before the India-Asia collision. Although the fold test is inconclusive based solely on our data, a positive reversal test, a positive regional fold test with previous paleomagnetic results, and a detrital origin of hematite in the red beds as indicated by scanning electron microscopy suggest that the magnetizations obtained from the Jurassic and Paleocene rocks are most likely primary, showing an 80° clockwise rotation since Paleocene. These results, together with previously published paleomagnetic data, suggest that the northern Sibumasu and northern Simao elements experienced a 60-80° clockwise rotation since Paleocene. This large clockwise rotation is also consistent with the surface GPS velocity field and NE-SW fault networks, suggesting a rotational motion of crustal material from southeastern Tibet during late Cenozoic. We infer that the large clockwise rotation is a sum of rotation in the Eocene to Middle Miocene time associated with Indochina extrusion and rotation after the Middle Miocene associated with the E-W extension in central Tibet. This suggests that the eastward motion of Tibetan crustal material along the Xianshuihe-Xiaojiang fault after Middle Miocene is transmitted to the southwest toward Myanmar. Jurassic and Cretaceous paleomagnetic results suggest that the Qiangtang/northern Sibumasu was originally a curved structure with an orientation of N60°W in Tibet and changes to N10°W in southern Sibumasu.

Changes in H reflex and neuromechanical properties of the trapezius muscle after 5 weeks of eccentric training: a randomized controlled trial.

PubMed

Vangsgaard, Steffen; Taylor, Janet L; Hansen, Ernst A; Madeleine, Pascal

2014-06-15

Trapezius muscle Hoffman (H) reflexes were obtained to investigate the neural adaptations induced by a 5-wk strength training regimen, based solely on eccentric contractions of the shoulder muscles. Twenty-nine healthy subjects were randomized into an eccentric training group (n = 15) and a reference group (n = 14). The eccentric training program consisted of nine training sessions of eccentric exercise performed over a 5-wk period. H-reflex recruitment curves, the maximal M wave (Mmax), maximal voluntary contraction (MVC) force, rate of force development (RFD), and electromyographic (EMG) voluntary activity were recorded before and after training. H reflexes were recorded from the middle part of the trapezius muscle by electrical stimulation of the C3/4 cervical nerves; Mmax was measured by electrical stimulation of the accessory nerve. Eccentric strength training resulted in significant increases in the maximal trapezius muscle H reflex (Hmax) (21.4% [5.5-37.3]; P = 0.01), MVC force (26.4% [15.0-37.7]; P < 0.01), and RFD (24.6% [3.2-46.0]; P = 0.025), while no significant changes were observed in the reference group. Mmax remained unchanged in both groups. A significant positive correlation was found between the change in MVC force and the change in EMG voluntary activity in the training group (r = 0.57; P = 0.03). These results indicate that the net excitability of the trapezius muscle H-reflex pathway increased after 5 wk of eccentric training. This is the first study to investigate and document changes in the trapezius muscle H reflex following eccentric strength training. Copyright © 2014 the American Physiological Society.

Birth outcomes among military personnel after exposure to documented open-air burn pits before and during pregnancy.

PubMed

Conlin, Ava Marie S; DeScisciolo, Connie; Sevick, Carter J; Bukowinski, Anna T; Phillips, Christopher J; Smith, Tyler C

2012-06-01

To examine birth outcomes in military women and men with potential exposure to documented open-air burn pits before and during pregnancy. Electronic data from the Department of Defense Birth and Infant Health Registry and the Defense Manpower Data Center were used to examine the prevalence of birth defects and preterm birth among infants of active-duty women and men who were deployed within a 3-mile radius of a documented open-air burn pit before or during pregnancy. In general, burn pit exposure at various times in relation to pregnancy and for differing durations was not consistently associated with an increase in birth defects or preterm birth in infants of active-duty military personnel. These analyses offer reassurance to service members that burn pit exposure is not consistently associated with these select adverse infant health outcomes.

Independent Orbiter Assessment (IOA): Assessment of the active thermal control system

NASA Technical Reports Server (NTRS)

Sinclair, S. K.

1988-01-01

The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the Active Thermal Control System (ATCS) hardware, generating draft failure modes and potential critical items. To preserve independence, this analysis was accomplished without reliance upon the results contained within the NASA FMEA/CIL documentation. The IOA results were then compared to the available NASA FMEA/CIL data. Discrepancies from the comparison were documented, and where enough information was available, recommendations for resolution of the discrepancies were made. This report documents the results of that comparison for the Orbiter ATCS hardware. The IOA product for the ATCS independent analysis consisted of 310 failure mode worksheets that resulted in 101 potential critical items (PCI) being identified. A comparison was made to the available NASA data which consisted of 252 FMEAs and 109 CIL items.

Spatial and mineralogic variation of Na-Ca alteration in Laramide porphyry systems of Arizona

NASA Astrophysics Data System (ADS)

Runyon, S.; Seedorff, E.; Barton, M. D.; Mazdab, F. K.; Lecumberri-Sanchez, P.; Steele-MacInnis, M.

2017-12-01

Na-Ca alteration is characterized by the metasomatic addition of Ca ± Na and the loss of K. Minor volumes of Na-Ca alteration in Laramide porphyry systems develops from 3 to 8 km paleodepth. Mineral assemblages, mineral compositions, hydrogen isotopes, whole-rock analyses, and reconnaissance fluid inclusion characteristics have been documented for Na-Ca alteration in Laramide porphyry systems such as Tea Cup and Sierrita. Volumetrically minor Na-Ca alteration in Laramide porphyry systems documented in this study commonly takes the form of one of three mineral assemblages: albite-epidote-chlorite, Na-plagioclase-actinolite ± epidote, and garnet- or diopside-stable Na-plagioclase-actinolite ± epidote. These different Na-Ca mineral assemblages have broad spatial relationships, from shallow albite-chlorite-epidote to deeper Na-plagioclase-actinolite within a given district. Hydrogen isotope data on Na-Ca alteration minerals shows consistently distinct δD compositions of Na-Ca alteration minerals compared to igneous minerals in a given district. Further, calculated hydrogen isotope composition of fluids in equilibrium with Na-Ca alteration minerals are consistently enriched in δD compared to magmatic-hydrothermal fluids. Whole-rock analyses show consistent losses of K and variable addition of Na and Ca across different Na-Ca alteration assemblages. Na-Ca alteration has been well documented associated with the Jurassic arc. Previous studies demonstrated through mass balance, timing and spatial relationships, isotopic, and fluid inclusion studies that Na-Ca alteration associated with the Jurassic arc likely formed from the circulation of external, highly saline, non-magmatic fluids (e.g., Battles and Barton, 1995; Dilles et al., 1995). Na-Ca alteration documented in Laramide systems is generally similar to Na-Ca alteration documented along the Jurassic arc in mineral assemblages, compositions, and timing, but the volume of Na-Ca alteration in the Laramide systems is small as compared to the voluminous Na-Ca alteration documented in systems associated with the Jurassic arc.