Science.gov

Sample records for doe review draft

  1. Implementation Plan for the Hawaii Geothermal Project Environmental Impact Statement (DOE Review Draft:)

    SciTech Connect

    1992-09-18

    The US Department of Energy (DOE) is preparing an Environmental Impact Statement (EIS) that identifies and evaluates the environmental impacts associated with the proposed Hawaii Geothermal Project (HGP), as defined by the State of Hawaii in its 1990 proposal to Congress (DBED 1990). The location of the proposed project is shown in Figure 1.1. The EIS is being prepared pursuant to the requirements of the National Environmental Policy Act of 1969 (NEPA), as implemented by the President's Council on Environmental Quality (CEQ) regulations (40 CFR Parts 1500-1508) and the DOE NEPA Implementing Procedures (10 CFR 1021), effective May 26, 1992. The State's proposal for the four-phase HGP consists of (1) exploration and testing of the geothermal resource beneath the slopes of the active Kilauea volcano on the Island of Hawaii (Big Island), (2) demonstration of deep-water power cable technology in the Alenuihaha Channel between the Big Island and Mau, (3) verification and characterization of the geothermal resource on the Big Island, and (4) construction and operation of commercial geothermal power production facilities on the Big Island, with overland and submarine transmission of electricity from the Big Island to Oahu and possibly other islands. DOE prepared appropriate NEPA documentation for separate federal actions related to Phase 1 and 2 research projects, which have been completed. This EIS will consider Phases 3 and 4, as well as reasonable alternatives to the HGP. Such alternatives include biomass coal, solar photovoltaic, wind energy, and construction and operation of commercial geothermal power production facilities on the Island of Hawaii (for exclusive use on the Big Island). In addition, the EIs will consider the reasonable alternatives among submarine cable technologies, geothermal extraction, production, and power generating technologies; pollution control technologies; overland and submarine power transmission routes; sites reasonably suited to support

  2. IRIS Toxicological Review of Mirex (2003 External Review Draft)

    EPA Science Inventory

    EPA is providing for public information a draft Toxicological Review, draft IRIS Summary, and charge to external peer reviewers for EPA's Health Assessment of Mirex. These documents are provided for public viewing during an external scientific peer review period. While EPA is not...

  3. IRIS Toxicological Review of Methanol (Noncancer) (Interagency Science Discussion Draft)

    EPA Science Inventory

    On May 3, 2013, the Toxicological Review of Methanol (noncancer) (Revised External Review Draft) was posted for public review and comment. Subsequently, the draft Toxicological Review, Appendices, and draft IRIS Summary were reviewed internally by EPA and by other federal agenci...

  4. Review the draft Title V with care

    SciTech Connect

    Romzick, P.G.; Heitz, D.R.

    1998-12-31

    The Title V permitting process is well underway for many industries and just beginning for others. Waste Management recently conducted the first in-depth reviews of draft Title V permits for some of its municipal solid waste (MSW) landfills. The Company`s comments on the draft permits were numerous. The draft permits contained some obvious as well as several less obvious errors. The results of these reviews identified a need to scrutinize carefully each and every draft permit issued to the Company`s landfills. The Company expects to require Title V permits for most of its 140 plus active landfills, due to the recently-enacted New Source Performance Standards for Municipal Solid Waste Landfills. Many issues of concern were encountered during the review. Had these issues not been identified, the facility would have had to live with an unnecessarily burdensome permit consisting of permit conditions that were more strict than the regulations required and lacking protections allowed by the law. This paper discusses many of the issues of concern identified during the draft permit review. Although many of the issues addressed in this paper are specific to MSW landfills, many of the issues are also applicable to Title V permits in general.

  5. IRIS Toxicological Review of Urea (External Review Draft) ...

    EPA Pesticide Factsheets

    EPA conducted a peer review and public comment of the scientific basis of a draft report supporting the human health hazard and dose-response assessment of Urea that when finalized will appear on the Integrated Risk Information System (IRIS) database. The draft Toxicological Review of Urea provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to Urea.

  6. IRIS Toxicological Review of Ammonia (Interagency Science Consultation Draft)

    EPA Science Inventory

    On June 1, 2012, the draft Toxicological Review of Ammonia and the draft charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House ...

  7. IRIS Toxicological Review of Trimethylbenzenes (Interagency Science Consultation Draft)

    EPA Science Inventory

    On June 26, 2012, the draft Toxicological Review of Trimethylbenzenes and the draft charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and W...

  8. IRIS Toxicological Review of Methanol (External Review Draft; December 2009)

    EPA Science Inventory

    NOTE: The IRIS Toxicological Review of Methanol (external review draft; December 2009) was released for public comment and external peer review in January 2010 (Federal Register Not...

  9. Integrated Science Assessment for Lead (Second External Review Draft)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) has been made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science...

  10. Integrated Science Assessment for Carbon Monoxide (First External Review Draft)

    EPA Science Inventory

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes have been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evalua...

  11. Integrated Science Assessment for Carbon Monoxide (Second External Review Draft)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes have been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evalu...

  12. Integrated Science Assessment for Lead (First External Review Draft)

    EPA Science Inventory

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) has been made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science ...

  13. Integrated Science Assessment for Particulate Matter (First External Review Draft)

    EPA Science Inventory

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Particulate Matter and related Annexes have been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and e...

  14. Integrated Science Assessment for Lead (Third External Review Draft)

    EPA Science Inventory

    EPA has announced that the Third External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) has been made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science ...

  15. IRIS Toxicological Review of Urea (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review and public comment of the scientific basis of a draft report supporting the human health hazard and dose-response assessment of Urea that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  16. IRIS Toxicological Review for Carbon Tetrachloride (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA released the draft report,Toxicological Review for Carbon Tetrachloride(Interagency Science Discussion Draft), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Co...

  17. IRIS Toxicological Review of Halogenated Platinum Salts and Platinum Compounds (External Review Draft)

    EPA Science Inventory

    EPA released the draft toxicological review for public comment under the Integrated Risk Information System (IRIS) Program. The original draft assessment (January 2009) has been archived but is available on this web page for the sake of transparency.

  18. IRIS Toxicological Review of Biphenyl (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 30, 2011, the draft Toxicological Review of Biphenyl and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House...

  19. IRIS Toxicological Review of Vanadium Pentoxide (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 30, 2011, the draft Toxicological Review of Vanadium Pentoxide and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and W...

  20. IRIS Toxicological Review of Acrylonitrile (Interagency Science Consultation Draft)

    EPA Science Inventory

    On June 30, 2011, the draft Toxicological Review of Acrylonitrile and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House...

  1. IRIS TOXICOLOGICAL REVIEW OF HEXAVALENT CHROMIUM (INTERAGENCY SCIENCE CONSULTATION DRAFT)

    EPA Science Inventory

    On Septemeber 30, 2010, the draft Toxicological Review of Hexavalent Chromium and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agenc...

  2. Basins 4.0 Climate Assessment Tool (Cat): Supporting Documentation and User Manual (External Review Draft)

    EPA Science Inventory

    EPA has released of the draft document solely for the purpose of pre-dissemination peer review under applicable Information Quality Guidelines (IQGs). This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agenc...

  3. Climate Change Vulnerability Assessments: Four Case Studies of Water Utility Practices (External Review Draft)

    EPA Science Inventory

    EPA has released this draft document solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy ...

  4. IRIS Toxicological Review of Trichloroethylene (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Trichloroethylene, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies ...

  5. A review of dynamics modelling of friction draft gear

    NASA Astrophysics Data System (ADS)

    Wu, Qing; Cole, Colin; Luo, Shihui; Spiryagin, Maksym

    2014-06-01

    Longer and heavier trains mean larger in-train forces and more complicated force patterns. Practical experience indicates that the development of fatigue failure of coupling systems in long heavy trains may differ from conventional understanding. The friction-type draft gears are the most widely used draft gears. The ever developing heavy haul transport environment requires further or new understanding of friction draft gear behaviour and its implications for train dynamics as well as fatigue damage of rolling stock. However, modelling of friction draft gears is a highly nonlinear question. Especially the poor predictability, repeatability and the discontinuity of friction make this task more challenging. This article reviews current techniques in dynamics modelling of friction draft gears to provide a starting point that can be used to improve existing or develop new models to achieve more accurate force amplitude and pattern predictions.

  6. IRIS Toxicological Review of Ammonia (Revised External Review Draft)

    EPA Science Inventory

    In August 2013, EPA submitted a revised draft IRIS assessment of ammonia to the agency's Science Advisory Board (SAB) and posted this draft on the IRIS website. EPA had previously released a draft of the assessment for public comment, held a public meeting about the draft, and ...

  7. IRIS Toxicological Review of Inorganic Arsenic (Cancer) (Interagency Science Consultation Draft)

    EPA Science Inventory

    On February 19, 2010, the draft IRIS Toxicological Review of Inorganic Arsenic (Cancer) external review draft document and the charge to external peer reviewers were released for public review and comment. The draft document and the charge to external peer reviewers were reviewed...

  8. Integrated Science Assessment for Particulate Matter (Second External Review Draft)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Particulate Matter (PM) have been made available for independent peer review and public review. The ISA reflects the latest scientific knowledge useful in indicating the kind...

  9. Draft safety review plan for accelerator production of tritium (APT) project

    SciTech Connect

    1997-07-01

    The purpose of this ``living`` Safety Review Plan (SRP) is to describe the products and processes that will be followed to conduct a systematic review of the Accelerator Production of Tritium (APT) Facility Preliminary Safety Analysis Report (PSAR), and subsequently to prepare a draft Safety Evaluation Report (SER) on the PSAR. This plan is prepared for and will be implemented by the APT Independent Safety Review Committee (ISRC) over the period July 1, 1997 through September 30, 1998, in accordance with provisions established in DOE-STD-1104-96. A core team of DOE, INEEL, and AMPARO Corporation engineers and scientists will prepare the initial draft SER with assistance from other ISRC team members on an as needed basis. Guidelines for preparing the draft SER are presented in Section 7 of this SRP. The PSAR reviews will focus exclusively on safety. The ever-present two-part question will be: Does the subject matter have safety significance? If so, does the APT structural, system, component, and/or process engineering design ensure an acceptable margin of safety? The APT mission, efficiency, and cost are not considerations of this plan. A more detailed discussion of the review philosophy is presented in Section 5 of this SRP.

  10. IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (Interagency Science Consultation Draft)

    EPA Science Inventory

    On March 31, 2010, the draft IRIS Toxicological Review of Dichloromethane (Methylene Chloride) external review draft document and the charge to external peer reviewers were released for public review and comment. The draft document and the charge to external peer reviewers were r...

  11. Impact assessment of draft DOE Order 5820.2B. Radioactive Waste Technical Support Program

    SciTech Connect

    1995-04-01

    The Department of Energy (DOE) has prepared a revision to DOE Order 5820.2A, entitled ``Radioactive Waste Management.`` DOE issued DOE Order 5820.2A in September 1988 and, as the title implies, it covered only radioactive waste forms. The proposed draft order, entitled ``Waste Management,`` addresses the management of both radioactive and nonradioactive waste forms. It also includes spent nuclear fuel, which DOE does not consider a waste. Waste forms covered include hazardous waste, high-level waste, transuranic (TRU) waste, low-level radioactive waste, uranium and thorium mill tailings, mixed waste, and sanitary waste. The Radioactive Waste Technical Support Program (TSP) of Leached Idaho Technologies Company (LITCO) is facilitating the revision of this order. The EM Regulatory Compliance Division (EM-331) has requested that TSP estimate the impacts and costs of compliance with the revised order. TSP requested Dames & Moore to aid in this assessment by comparing requirements in Draft Order 5820.2B to ones in DOE Order 5820.2A and other DOE orders and Federal regulations. The assessment started with a draft version of 5820.2B dated January 14, 1994. DOE has released three updated versions of the draft order since then (dated May 20, 1994; August 26, 1994; and January 23, 1995). Each time DOE revised the order, Dames and Moore updated the assessment work to reflect the text changes. This report reflects the January 23, 1995 version of the draft order.

  12. IRIS Toxicological Review of Trimethylbenzenes (Revised External Review Draft)

    EPA Science Inventory

    In August 2013, EPA submitted a revised draft IRIS assessment of trimethylbenzenes to the agency's Science Advisory Board (SAB) and posted this draft on the IRIS website. EPA had previously released a draft of the assessment for public comment, held a public meeting about the dr...

  13. 76 FR 60055 - Draft Guidance for Industry: Applications for Premarket Review of New Tobacco Products...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry: Applications for Premarket Review of New Tobacco Products; Availability; Agency Information Collection Activities; Proposed... ``Applications for Premarket Review of New Tobacco Products.'' The draft guidance is intended to assist...

  14. IRIS Toxicological Review of Libby Amphibole Asbestos (Interagency Science Discussion Draft)

    EPA Science Inventory

    On August 25, 2011, the draft assessment of Libby Amphibole asbestos was released for external peer review and public comment. The draft assessment was revised based on peer review comments from EPA’s Science Advisory Board (SAB) and public comments. The revised draft was review...

  15. 77 FR 36534 - Third External Review Draft Integrated Science Assessment for Ozone and Related Photochemical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... AGENCY Third External Review Draft Integrated Science Assessment for Ozone and Related Photochemical... External Review Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants'' (EPA/600... Standards (NAAQS) for ozone. EPA is releasing this draft document to seek review by the Clean Air...

  16. IRIS Toxicological Review of Chloroprene (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Chloroprene, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Co...

  17. IRIS Toxicological Review of Biphenyl (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Biphenyl, that was distributed to other federal agencies and the Executive Office of the President for comment during Interagency Science Discussion (IASD) (Step 6b) of the IRIS assessment development process. Interagenc...

  18. IRIS Toxicological Review for Acrylamide (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review for Acrylamide, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process<...

  19. IRIS Toxicological Review of Pentachlorophenol (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Pentachlorophenol, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Pr...

  20. IRIS Toxicological Review of Tetrahydrofuran (THF) (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Tetrahydrofuran, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Proc...

  1. IRIS TOXICOLOGICAL REVIEW OF TETRACHLOROETHYLENE (PERCHLOROETHYLENE) (INTERAGENCY SCIENCE DISCUSSION DRAFT)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Tetrachloroethylene (Perchloroethylene), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment...

  2. 78 FR 23289 - Public Review of Draft National Shoreline Data Content Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... Geological Survey Public Review of Draft National Shoreline Data Content Standard AGENCY: Department of the... Content Standard. SUMMARY: The Federal Geographic Data Committee (FGDC) is conducting a public review of the draft National Shoreline Data Content Standard. The FGDC has developed a draft National...

  3. IRIS Toxicological Review of Benzo[a]pyrene (Interagency Science Consultation Draft)

    EPA Science Inventory

    On August 21, 2013, the draft Toxicological Review of Benzo[a]pyrene and the draft charge to external peer reviewers were released for public review and comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offi...

  4. 75 FR 4067 - Release of Draft Documents Related to the Review of the National Ambient Air Quality Standards...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-26

    ... Matter Urban- Focused Visibility Assessment--Second External Review Draft. On or about January 29, 2010, OAQPS is making available for public comment a second draft assessment document titled, Quantitative Health Risk Assessment for Particulate Matter--Second External Review Draft. These two draft...

  5. Integrated Science Assessment (ISA) for Lead (Second External Review Draft, Mar 2012)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) has been made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science...

  6. Integrated Science Assessment (ISA) for Lead (Third External Review Draft, Nov 2012)

    EPA Science Inventory

    EPA announced that the Third External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) was made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science and will ...

  7. Integrated Science Assessment (ISA) for Particulate Matter (First External Review Draft, Dec 2008)

    EPA Science Inventory

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Particulate Matter and related Annexes have been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and e...

  8. Integrated Science Assessment (ISA) for Carbon Monoxide (First External Review Draft, Mar 2009)

    EPA Science Inventory

    EPA announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes was made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of th...

  9. Integrated Science Assessment (ISA) for Carbon Monoxide (Second External Review Draft, Sep 2009)

    EPA Science Inventory

    EPA announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes was made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of t...

  10. Integrated Science Assessment (ISA) of Ozone and Related Photochemical Oxidants (First External Review Draft, Feb 2011)

    EPA Science Inventory

    EPA announced that the First External Review Draft of the Integrated Science Assessment for Ozone and Related Photochemical Oxidants has been made available for independent peer review and public review. This draft document represents a concise synthesis and evaluation of ...

  11. Integrated Science Assessment (ISA) for Lead (First External Review Draft, May 2011)

    EPA Science Inventory

    EPA announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) was made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science and will ...

  12. Integrated Science Assessment (ISA) of Ozone and Related Photochemical Oxidants (Third External Review Draft, Jun 2012)

    EPA Science Inventory

    EPA has released the Integrated Science Assessment of Ozone and Related Photochemical Oxidants (Third External Review Draft) for independent peer review and public review. This draft document represents a concise synthesis and evaluation of the most policy-relevant science...

  13. Integrated Science Assessment (ISA) of Ozone and Related Photochemical Oxidants (Second External Review Draft, Sep 2011)

    EPA Science Inventory

    EPA has released the Integrated Science Assessment of Ozone and Related Photochemical Oxidants (Second External Review Draft) for independent peer review and public review. This draft document represents a concise synthesis and evaluation of the most policy-relevant scienc...

  14. IRIS Toxicological Review of Tert-Butyl Alcohol (Tert-Butanol) (Interagency Science Consultation Draft)

    EPA Science Inventory

    On April 29, 2016, the Toxicological Review of tert-Butyl Alcohol (tert-Butanol) (Public Comment Draft) was released for public comment. The draft Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and the Executive Office ...

  15. Integrated Science Assessment of Ozone and Related Photochemical Oxidants (Second External Review Draft)

    EPA Science Inventory

    EPA has released the Integrated Science Assessment of Ozone and Related Photochemical Oxidants (Second External Review Draft) for independent peer review and public review. This draft document represents a concise synthesis and evaluation of the most policy-relevant scienc...

  16. Integrated Science Assessment of Ozone and Related Photochemical Oxidants (Third External Review Draft)

    EPA Science Inventory

    EPA has released the Integrated Science Assessment of Ozone and Related Photochemical Oxidants (Third External Review Draft) for independent peer review and public review. This draft document represents a concise synthesis and evaluation of the most policy-relevant science...

  17. Integrated Science Assessment of Ozone and Related Photochemical Oxidants (First External Review Draft)

    EPA Science Inventory

    EPA announced that the First External Review Draft of the Integrated Science Assessment for Ozone and Related Photochemical Oxidants has been made available for independent peer review and public review. This draft document represents a concise synthesis and evaluation of ...

  18. Integrated Science Assessment for Oxides of Nitrogen – Health Criteria (Second External Review Draft, 2008)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation...

  19. An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios (External Review Draft)

    EPA Science Inventory

    EPA has released an external review draft entitled, An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios(External Review Draft). The public comment period and the external peer-review workshop are separate processes that provide opportunities ...

  20. Integrated Science Assessment for Oxides of Nitrogen – Health Criteria (First External Review Draft, 2007)

    EPA Science Inventory

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and eva...

  1. 78 FR 17653 - Upper Great Plains Wind Energy Draft Programmatic Environmental Impact Statement (DOE/EIS-0408)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... Wind Energy Draft Programmatic Environmental Impact Statement (DOE/EIS-0408) AGENCIES: Western Area... Service (Service), have, as joint lead agencies, prepared the Upper Great Plains Wind Energy Draft... wind energy development within Western's Upper Great Plains Customer Service Region (UGP Region),...

  2. Review of the Draft 2014 Science Mission Directorate Science Plan

    NASA Technical Reports Server (NTRS)

    2013-01-01

    At the request of NASA's Science Mission Directorate (SMD), the National Research Council's (NRC's) Space Studies Board (SSB) initiated a study to review a draft of the SMD's 2014 Science Plan. The request for this review was made at a time when NASA is engaged in the final stages of a comprehensive, agency-wide effort to develop a new strategic plan and at a time when NASA's budget is under considerable stress. SMD's Science Plan serves to provide more detail on its four traditional science disciplines-astronomy and astrophysics, solar and space physics (also called heliophysics), planetary science, and Earth remote sensing and related activities-than is possible in the agency-wide Strategic Plan. In conducting its review of the draft Science Plan, the Committee on the Assessment of the NASA Science Mission Directorate 2014 Science Plan was charged to comment on the following specific areas: (1) Responsiveness to the NRC's guidance on key science issues and opportunities in recent NRC reports; (2) Attention to interdisciplinary aspects and overall scientific balance; (3) Identification and exposition of important opportunities for partnerships as well as education and public outreach; (4) Integration of technology development with the science program; (5) Clarity on how the plan aligns with SMD's strategic planning process; (6) General readability and clarity of presentation; and (7) Other relevant issues as determined by the committee. The main body of the report provides detailed findings and recommendations relating to the draft Science Plan. The highest-level, crosscutting issues are summarized here, and more detail is available in the main body of the report.

  3. Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria (First External Review Draft, 2013)

    EPA Science Inventory

    EPA is announcing the availability of the First External Review Draft of the Integrated Science Assessment for Oxides of Nitrogen – Health Criteria for public comment and independent peer review. This draft document provides EPA’s evaluation and synthesis of the most polic...

  4. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (External Review Draft, Nov 2015)

    EPA Science Inventory

    EPA announced the availability of the external review draft of the Integrated Science Assessment for Sulfur Oxides– Health Criteria for public comment and independent peer review in a November 24, 2015 Federal Register Notice. This draft document provides EPA’s evaluati...

  5. Integrated Science Assessment for Oxides of Nitrogen – Health Criteria (First External Review Draft, 2013)

    EPA Science Inventory

    EPA is announcing the availability of the First External Review Draft of the Integrated Science Assessment for Oxides of Nitrogen – Health Criteria for public comment and independent peer review. This draft document provides EPA’s evaluation and synthesis of the most polic...

  6. 49 CFR 520.25 - External review of draft environmental impact statements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 6 2013-10-01 2013-10-01 false External review of draft environmental impact... ENVIRONMENTAL IMPACTS Procedures § 520.25 External review of draft environmental impact statements. (a... by law or special expertise with respect to the possible environmental impact involved, and from...

  7. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (Etbe) (Interagency Science Consultation Draft)

    EPA Science Inventory

    In September 2016, EPA released the draft IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) for public comment and discussion. The draft assessment was reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent ...

  8. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (Etbe) (Public Comment Draft)

    EPA Science Inventory

    In September 2016, the U.S. Environmental Protection Agency's (USEPA) released the draft Integrated Risk Information System (IRIS) Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE). Consistent with the 2013 IRIS Enhancements, draft IRIS assessments are released prior to e...

  9. 75 FR 44790 - Second Draft Document Related to the Review of the National Ambient Air Quality Standards for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... AGENCY Second Draft Document Related to the Review of the National Ambient Air Quality Standards for... Ambient Air Quality Standards--Second External Review Draft. The EPA is extending the comment period for... chapter 4 of the second draft Policy Assessment. The original comment period was to end on August 16,...

  10. 75 FR 10252 - Release of Draft Documents Related to the Review of the National Ambient Air Quality Standards...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ...--Second External Review Draft. This draft document describes the quantitative analyses that are being... results, observations, and related uncertainties associated with the quantitative analyses performed. An... primary (health-based) CO NAAQS, the Agency is conducting qualitative and quantitative...

  11. IRIS Toxicological Review of Libby Amphibole Asbestos (Interagency Science Consultation Draft)

    EPA Science Inventory

    On August 25, 2011, the draft Toxicological Review of Libby Amphibole Asbestos and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies an...

  12. IRIS Toxicological Review of 1,4-Dioxane (with Inhalation Update) (Interagency Science Discussion Draft)

    EPA Science Inventory

    On September 9, 2011, the Toxicological Review of 1,4-Dioxane (inhalation) (External Review Draft) was posted for external peer review and public comment. Subsequently, the Toxicological Review and IRIS Summary were reviewed internally by EPA and by other federal agencies and Exe...

  13. IRIS Toxicological Review of n-Butanol (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 8, 2011, the Toxicological Review of n-Butanol (External Review Draft) was released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public re...

  14. IRIS Toxicological Review of 1,4-Dioxane (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 9, 2011, the Toxicological Review of 1,4-Dioxane (with inhalation update) (External Review Draft) was posted for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House...

  15. A Screening Assessment of the Potential Impacts of Climate Change on Combined Sewer Overflow (Cso) Mitigation in the Great Lakes and New England Regions (External Review Draft)

    EPA Science Inventory

    EPA has released this draft document solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy ...

  16. IRIS Toxicological Review of Carbon Tetrachloride (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of carbon tetrachloride that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and...

  17. IRIS Toxicological Review of Nitrobenzene (External Review Draft)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessments of nitrobenzene, that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and a...

  18. IRIS Toxicological Review of Tetrachloroethylene (Perchloroethylene) (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of tetrachloroethylene that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and ...

  19. IRIS Toxicological Review of Bromobenzene (External Review Draft)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of Bromobenzene that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and app...

  20. IRIS Toxicological Review of Hexavalent Chromium (2010 External Review Draft)

    EPA Science Inventory

  1. IRIS Toxicological Review of Acrylamide (External Review Draft)

    EPA Science Inventory

    EPA has conducted a peer review by EPA’s Science Advisory Board (SAB) of the scientific basis supporting the human health hazard and dose-response assessment of acrylamide that once finalized will appear on the Integrated Risk Information System (IRIS) database. Peer review is m...

  2. IRIS Toxicological Review of 2-Hexanone (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 2-hexanone that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and appro...

  3. IRIS Toxicological Review of Libby Amphibole Asbestos (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of Libby Amphibole Asbestos that will appear in the Integrated Risk Information System (IRIS) database.

  4. IRIS Toxicological Review of Hexachloroethane (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of hexachloroethane that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  5. IRIS Toxicological Review of Trichloroacetic Acid (TCA) (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Trichloroacetic acid (TCA) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  6. IRIS Toxicological Review of Trimethylbenzenes (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of trimethylbenzenes that will appear in the Integrated Risk Information System (IRIS) database.

  7. IRIS Toxicological Review of Chloroprene (2000 External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of chloroprene that will appear on the Integrated Risk Information System (IRIS) database.

  8. IRIS Toxicological Review of Chloroprene (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of chloroprene that will appear on the Integrated Risk Information System (IRIS) database.

  9. IRIS Toxicological Review of Hydrogen Cyanide (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of hydrogen cyanide and cyanide salts that will appear on the Integrated Risk Information System (IRIS) database.

  10. IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Dichloromethane that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  11. IRIS Toxicological Review of Trichloroethylene (TCE) (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Trichloroethylene (TCE) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  12. IRIS Toxicological Review of Formaldehyde (Inhalation) (External Review Draft 2010)

    EPA Science Inventory

    UPDATE EPA is currently revising its Integrated Risk Information System (IRIS) assessment of formaldehyde to address the 2011 NAS peer review recommendations. This assessment addresses both noncancer and cancer human health effects that are relevant to assessing ...

  13. IRIS Toxicological Review of Pentachlorophenol (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of pentachlorophenol that will appear in the Integrated Risk Information System (IRIS) database.

  14. IRIS Toxicological Review of Propionaldehyde (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of propionaldehyde that will appear on the Integrated Risk Information System (IRIS) database.

  15. IRIS Toxicological Review of Tetrahydrofuran (Thf) (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of tetrahydrofuran (THF) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  16. IRIS Toxicological Review of n-Butanol (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of n-butanol that will appear in the Integrated Risk Information System (IRIS) database.

  17. IRIS Toxicological Review of Biphenyl (External Review Draft) (September 2011)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of biphenyl that will appear in the Integrated Risk Information System (IRIS) database.

  18. IRIS Toxicological Review of Ammonia (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of ammonia that will appear in the Integrated Risk Information System (IRIS) database.

  19. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (Rdx) (Interagency Science Consultation Draft)

    EPA Science Inventory

    On March 10, 2016, the public comment draft Toxicological Review of Hexahydro-1,3,5-trinitro-1,3,5-triazine and the draft charge to external peer reviewers were released for public review and comment. The Toxicological Review and charge were reviewed internally by EPA and by othe...

  20. RE: Request for Correction - SAB Workgroup Review of Draft IRIS Assessment for Inorganic Arsenic

    EPA Pesticide Factsheets

    Request from Lynn Bergeson for the correction of information in the draft EPA document Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS).

  1. Best Practices for Continuous Monitoring of Temperature and Flow in Wadeable Streams (External Review Draft)

    EPA Science Inventory

    This external review draft report is a technical "best practices" document describing sensor deployment for and data collection of continuous temperature and flow at ungaged sites in wadeable streams. This document addresses questions related to equipment needs; configuration, pl...

  2. IRIS Toxicological Review of Benzo[a]pyrene (Public Comment Draft)

    EPA Science Inventory

    EPA is developing an Integrated Risk Information System (IRIS) assessment of benzo[a]pyrene and has released the draft assessment for public comment and external peer review. When final, the assessment will appear on the IRIS database.

  3. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 1: Plenary Session

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Briefings from the plenary session of the conference on SSTAC/ARTS Review of the Draft Integrated Technology Plan (ITP) held on 24-28 Jun. 1991 are included. Viewgraphs from the presentations are included.

  4. Nanomaterial Case Studies: Nanoscale Titanium Dioxide (External Review Draft)

    EPA Science Inventory

    This draft document presents two case studies of nanoscale titanium dioxide (nano-TiO2) used (1) to remove arsenic from drinking water and (2) as an active ingredient in topical sunscreen. The draft case studies are organized around a comprehensive environmental asses...

  5. IRIS Toxicological Review of Methanol (External Review Draft, 2013)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of methanol (non-cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  6. IRIS Toxicological Review of Methanol (Noncancer) (Revised External Review Draft)

    EPA Science Inventory

    EPA is seeking additional public comment and external peer review of the scientific basis supporting the human health hazard and dose-response assessment of methanol (noncancer).

  1. Review and Update Contents of Drafting Curriculum Guides. Final Report.

    ERIC Educational Resources Information Center

    Sherrell, Eugene G.

    A study was undertaken to determine whether the curriculum guides presently being used in drafting courses have changed due to the technological developments that have occurred in industry. In addition, the survey was concerned with the extent that knowledge of geometric dimensioning and tolerancing are needed by drafters, the extent that the…

  2. 78 FR 70047 - Request for the Technical Review of 25 Draft Skin Notation Assignments and Skin Notation Profiles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... Skin Notation Assignments and Skin Notation Profiles AGENCY: National Institute for Occupational Safety... review of the draft skin notations and supporting technical documents entitled, Skin Notations Profiles, for 25 chemicals. NIOSH is requesting technical reviews of the draft Skin Notation Profiles....

  3. 75 FR 22148 - Request for the Technical Review of 22 Draft Skin Notation Assignments and Skin Notation Profiles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-27

    ... Skin Notation Assignments and Skin Notation Profiles AGENCY: National Institute for Occupational Safety... public review of the draft skin notations and support technical documents entitled ``Skin Notations Profiles, for 22 chemicals.'' NIOSH is requesting technical reviews of the draft Skin Notation Profiles....

  4. 75 FR 39253 - Release of Second Draft Document Related to the Review of the National Ambient Air Quality...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... AGENCY Release of Second Draft Document Related to the Review of the National Ambient Air Quality... Assessment for the Review of the Particulate Matter National Ambient Air Quality Standards--Second External...: http://www.epa.gov/ttn/naaqs/standards/pm/s_pm_2007_risk.html . The second draft Policy...

  5. 77 FR 51798 - First Draft Documents Related to the Review of the National Ambient Air Quality Standards for Ozone

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ... Ozone AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of extension of comment period... documents titled, Health Risk and Exposure Assessment for Ozone, First External Review Draft; Welfare Risk and Exposure Assessment for Ozone, First External Review Draft; and Policy Assessment for the...

  6. 77 FR 34039 - Draft Toxicological Review of Ammonia: In Support of the Summary Information in the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... AGENCY Draft Toxicological Review of Ammonia: In Support of the Summary Information in the Integrated... Review of Ammonia: In Support of Summary Information on the Integrated Risk Information System (IRIS... on the draft IRIS health assessment for ammonia will be held on July 12, 2012, beginning at 9...

  7. 77 FR 42495 - Release of Draft Documents Related to the Review of the National Ambient Air Quality Standards...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-19

    ... Ozone, First External Review Draft. These two draft assessment documents describe the quantitative analyses the EPA is conducting as part of the review of the national ambient air quality standards (NAAQS... NAAQS,\\3\\ the Agency is conducting quantitative assessments characterizing the: (1) Health...

  8. 75 FR 29588 - Office of New Reactors: Proposed NUREG-0800; Standard Review Plan Section 13.6.6, Draft Revision...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... NUREG-0800; Standard Review Plan Section 13.6.6, Draft Revision 0 on Cyber Security Plan AGENCY: Nuclear... Nuclear Power Plants,'' on a proposed Standard Review Plan (SRP) Section 13.6.6 on ``Cyber Security...

  9. IRIS Toxicological Review of Trichloroacetic Acid (TCA) (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Trichloroacetic Acid (TCA), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development ...

  10. IRIS Toxicological Review of Ethylene Glycol Mono-Butyl Ether (Egbe) (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA released the draft report, Toxicological Review for Ethylene Glycol Mono-Butyl Ether , that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from ot...

  11. 77 FR 34958 - Draft Guidance for Institutional Review Boards, Clinical Investigators, and Sponsors...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... may vary. To enhance human subject protections and reduce regulatory burden, FDA and the Office for Human Research Protections (OHRP) have been actively working to harmonize the Agencies' regulatory... HUMAN SERVICES Food and Drug Administration Draft Guidance for Institutional Review Boards,...

  12. IRIS Toxicological Review of 1,1,2,2-Tetrachloroethane (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of 1,1,2,2-Tetrachloroethane, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Develo...

  13. 75 FR 1790 - Draft Guidance for Institutional Review Boards, Clinical Investigators, and Sponsors: IRB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Institutional Review Boards, Clinical... Approval'' (September 1998, Office of Health Affairs, Food and Drug Administration). To enhance human subject protection and reduce regulatory burden, the Department of Health and Human Services, Office...

  14. 49 CFR 520.25 - External review of draft environmental impact statements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... jurisdiction of the Environmental Protection Agency (air or water quality, solid wastes, pesticides, radiation... 49 Transportation 6 2014-10-01 2014-10-01 false External review of draft environmental impact statements. 520.25 Section 520.25 Transportation Other Regulations Relating to Transportation...

  15. 49 CFR 520.25 - External review of draft environmental impact statements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... jurisdiction of the Environmental Protection Agency (air or water quality, solid wastes, pesticides, radiation... 49 Transportation 6 2011-10-01 2011-10-01 false External review of draft environmental impact statements. 520.25 Section 520.25 Transportation Other Regulations Relating to Transportation...

  16. 49 CFR 520.25 - External review of draft environmental impact statements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... jurisdiction of the Environmental Protection Agency (air or water quality, solid wastes, pesticides, radiation... 49 Transportation 6 2010-10-01 2010-10-01 false External review of draft environmental impact statements. 520.25 Section 520.25 Transportation Other Regulations Relating to Transportation...

  17. 49 CFR 520.25 - External review of draft environmental impact statements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... jurisdiction of the Environmental Protection Agency (air or water quality, solid wastes, pesticides, radiation... 49 Transportation 6 2012-10-01 2012-10-01 false External review of draft environmental impact statements. 520.25 Section 520.25 Transportation Other Regulations Relating to Transportation...

  18. IRIS Toxicological Review of Hydrogen Cyanide and Cyanide Salts (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Hydrogen Cyanide (HCN) and Cyanide Salts, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS As...

  19. IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Dichloromethane, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Proc...

  20. 78 FR 13686 - Draft Guidance for Industry and Review Staff on Pediatric Information Incorporated Into Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-28

    ... amended by the Food and Drug Administration Safety and Innovation Act (FDASIA), as well as FDA... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Review Staff on Pediatric...: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA)...

  1. 76 FR 80948 - Draft Guidance for Industry, Clinical Investigators, Institutional Review Boards, and Food and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ... developed to promote the initiation of clinical investigations to evaluate the medical devices under FDA's... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry, Clinical Investigators, Institutional Review Boards, and Food and Drug Administration Staff; Food and Drug Administration Decisions...

  2. 76 FR 54228 - Draft Toxicological Review of Acrylonitrile: In Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... Acrylonitrile: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R... Acrylonitrile: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available... AGENCY Draft Toxicological Review of Acrylonitrile: In Support of Summary Information on the...

  3. 75 FR 50761 - Draft Toxicological Review of Dichloromethane: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-17

    ... Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R-10/003A). The... Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available primarily... AGENCY Draft Toxicological Review of Dichloromethane: In Support of Summary Information on the...

  4. 76 FR 60825 - Draft Toxicological Review of Vanadium Pentoxide: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of..., ``Toxicological Review of Vanadium Pentoxide: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R-11/004A). The draft assessment was prepared by the National Center...

  5. Biofuels and the Environment: The First Triennial Report to Congress (External Review Draft)

    EPA Science Inventory

    The Biofuels and the Environment: The First Triennial Report to Congress (External Review Draft) (EPA/600/R-10/183A) report, prepared by the National Center for Environmental Assessment (NCEA) within EPA’s Office of Research and Development, is the first report published ...

  6. 78 FR 65980 - Notice of Availability for Public Review and Comment: Draft EPA Climate Change Adaptation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... AGENCY Notice of Availability for Public Review and Comment: Draft EPA Climate Change Adaptation... demonstrates that the climate is changing at an increasingly rapid rate, outside the range to which society has adapted in the past. Climate change can pose significant challenges to the EPA's ability to fulfill...

  7. IRIS Toxicological Review of cis- & trans-1,2-Dichloroethylene (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of cis-1,2-Dichloroethylene and trans-1,2-Dichloroethylene, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 5: Human Support

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Viewgraphs of briefings from the Space Systems and Technology Advisory Committee (SSTAC)/ARTS review of the draft integrated technology plan (ITP) on human support are included. Topics covered include: human support program; human factors; life support technology; fire safety; medical support technology; advanced refrigeration technology; EVA suit system; advanced PLSS technology; and ARC-EVA systems research program.

  8. IRIS Toxicological Review of Tert-Butyl Alcohol (Tert-Butanol) (Public Comment Draft)

    EPA Science Inventory

    EPA is developing an Integrated Risk Information System (IRIS) assessment of tert-butyl Alcohol (tert-butanol) and has released the public comment draft assessment for public comment and external peer review. When final, the assessment will appear on the IRIS databa...

  9. 75 FR 69065 - Draft Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R-10/005). The draft assessment was... Urea: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available... AGENCY Draft Toxicological Review of Urea: In Support of Summary Information on the Integrated...

  10. 77 FR 7576 - Draft Toxicological Review of 1,4-Dioxane: In Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... Support of Summary Information on the Integrated Risk Information System (IRIS)'' . The draft assessment...-Dioxane: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available... AGENCY Draft Toxicological Review of 1,4-Dioxane: In Support of Summary Information on the...

  11. Less Than Proficient A Review of the Draft Science Framework for the 2009 National Assessment of Educational Progress

    ERIC Educational Resources Information Center

    Gross, Paul R.

    2005-01-01

    The mission of this review is to appraise the new draft NAEP science framework and to determine whether it is up to snuff. This is an evaluation of the September 30, 2005, draft document, Science Framework for the 2009 National Assessment of Educational Progress (Framework), developed for the National Assessment Governing Board. The criteria is…

  12. Next Generation Risk Assessment: Incorporation of Recent Advances in Molecular, Computational, and Systems Biology (External Review Draft)

    EPA Science Inventory

    Cover of the Next Generation of Risk Assessment (External <span class=Review Draft)" vspace = "5" hspace="5" align="right" border="1" /> EPA is releasing a draft report "Next Generation Risk Assessment: I...

  13. EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (External Review Draft)

    EPA Science Inventory

  1. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 6: Controls and guidance

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Viewgraphs of briefings from the Space Systems and Technology Advisory Committee (SSTAC)/ARTS review of the draft Integrated Technology Plan (ITP) on controls and guidance are included. Topics covered include: strategic avionics technology planning and bridging programs; avionics technology plan; vehicle health management; spacecraft guidance research; autonomous rendezvous and docking; autonomous landing; computational control; fiberoptic rotation sensors; precision instrument and telescope pointing; microsensors and microinstruments; micro guidance and control initiative; and earth-orbiting platforms controls-structures interaction.

  2. Air Quality Criteria for Lead (First External Review Draft)

    EPA Science Inventory

    Background:

    The Clean Air Act mandates periodic review of the National Ambient Air Quality Standards (NAAQS) for six common air pollutants, also referred to as criteria pollutants, including lead. Under the review process, EPA's Office of Research and Development d...

  3. AIR QUALITY CRITERIA FOR LEAD (SECOND EXTERNAL REVIEW DRAFT)

    EPA Science Inventory

    The Clean Air Act mandates periodic review of the National Ambient Air Quality Standards (NAAQS) for six common air pollutants, also referred to as criteria pollutants, including lead. Under the review process, EPA's Office of Research and Development develops a criteria docu...

  4. IRIS Toxicological Review of Trimethylbenzenes (Interagency Science Discussion Draft)

    EPA Science Inventory

    In September 2016, EPA finalized the IRIS assessment of Trimethylbenzenes. The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices before public release in June 2016. Consistent with the May 2009 IRIS assessment development pr...

  5. 75 FR 9228 - Draft Guidance for Industry on Non-Inferiority Clinical Trials; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-01

    ... ``Non- Inferiority Clinical Trials.'' This draft guidance provides sponsors and review staff in the... announcing the availability of a draft guidance for industry entitled ``Non-Inferiority Clinical Trials... clinical trials. It does not create or confer any rights for or on any person and does not operate to...

  6. 78 FR 32237 - Draft Initial Comprehensive Plan and Draft Programmatic Environmental Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ... Office of the Secretary Draft Initial Comprehensive Plan and Draft Programmatic Environmental Assessment... comments. SUMMARY: In accordance with the Resources and Ecosystems Sustainability, Tourist Opportunities... Environmental Assessment (Draft PEA) for the Draft Plan. These documents are available for public review...

  7. Memoranda Associated with the Second External Review Draft of Health Risk and Exposure Assessments from the Current Review of Ozone NAAQS

    EPA Pesticide Factsheets

    EPA's Health and Environmental Impacts Division had to make corrections to some of the risk results included in earlier drafts of the Health Risk and Exposure Assessment from the current review of ozone national ambient air quality standards (NAAQS).

  8. Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (Revised August 2014 External Review Draft) (SAB Review Draft)

    EPA Science Inventory

    EPA is seeking peer review of the scientific basis supporting the human health hazard and dose-response assessment of ethylene oxide (cancer) that will appear in the Integrated Risk Information System (IRIS) database.

  9. 46 CFR 131.220 - Drafts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... stem or cutaway skeg, the keel does not extend forward or aft to the draft markings, the datum...

  10. 76 FR 53125 - Draft Toxicological Review of Libby Amphibole Asbestos: In Support of the Summary Information on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-25

    ... AGENCY Draft Toxicological Review of Libby Amphibole Asbestos: In Support of the Summary Information on... ``Toxicological Review of Libby Amphibole Asbestos: In Support of Summary Information on the Integrated Risk... IRIS health assessment for Libby Amphibole Asbestos will be held in Arlington, VA, on October 6,...

  11. 76 FR 57033 - Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... ``Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System... AGENCY Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of Public...

  12. 76 FR 54225 - Draft Toxicological Review of 1,4-Dioxane: In Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... Review of 1,4-Dioxane: In Support of Summary Information on the Integrated Risk Information System (IRIS...-Dioxane: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available... AGENCY Draft Toxicological Review of 1,4-Dioxane: In Support of Summary Information on the...

  13. 76 FR 23755 - Release of Draft Risk and Exposure Assessments and Final Integrated Review Plan for the National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-28

    ... AGENCY 40 CFR Parts 50 and 58 RIN 2060-AP38 Release of Draft Risk and Exposure Assessments and Final Integrated Review Plan for the National Ambient Air Quality Standards for Ozone AGENCY: Environmental... making available for public review the documents titled, ``Ozone National Ambient Air Quality...

  14. Problem Formulation for Human Health Risk Assessments of Pathogens in Land-Applied Biosolids (External Review Draft)

    EPA Science Inventory

    This is a draft document and as such has not been formally disseminated by the U.S. EPA; it does not represent - and should not be construed to represent - any U.S. EPA policy or determination. Under applicable information quality guidelines, the document is being released for a...

  15. The process of consensus on EMF: SAB review of the EPA draft document on EMF and cancer

    NASA Astrophysics Data System (ADS)

    Wilson, B. W.

    1992-06-01

    The EPA Draft Document on EMF and Cancers grew out of an earlier effort by EPA to track biological effects literature relative to radio-frequency (RF) exposure. Scope of the document was broadened to include extremely low frequency electric and magnetic fields prior to an announcement in 1986 that EPA would formally review the whole area of non-ionizing radiation. An extensive survey of the relevant bioeffects and epidemiologic literature was carried out, and writing on the document began in earnest on the document sometime in 1989. In its draft form, the document reviewed the literature on mechanisms of Interaction between electromagnetic fields and biological tissue, EMF epidemiologic studies, supporting evidence for carcinogenicity and research needs. In the early summer of 1990, a draft of the document was reviewed by some 22 individuals within the EPA and other government agencies. It was also sent out for external review to an additional 9 qualified scientists who had worked in the area and were familiar with EMF-related literature in epidemiology, biology, and physics. Many of the comments sent to EPA from this first review, prior to release of the draft for public comment, were strikingly similar to those resulting from the second (public) review process. Thus, it appears that much of the controversy that was later associated with the document could have been avoided had the authors been diligent in following the recommendations of the initial set of reviewers.

  16. 77 FR 76474 - Extension of Public Review and Comment Period for the Draft Programmatic Environmental Assessment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... of availability for the Draft Programmatic Environmental Assessment (PEA) for the Recycling of Scrap... that notice, the email address for submitting comments on the Draft PEA contained an error. On December... address printed in the Draft PEA was correct and now both that email address (...

  17. 77 FR 69920 - Notice of Availability for Public Review of the Draft Tier 1 Environmental Impact Statement for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... TRANSPORTATION Federal Railroad Administration Notice of Availability for Public Review of the Draft Tier 1... well as the lack of competitive and attractive travel alternatives to highway and air transportation...: Federal Railroad Administration (FRA), U.S. Department of Transportation (DOT). ACTION: Notice...

  18. 76 FR 43999 - Notice of Availability of the External Review Draft of the Guidance for Applying Quantitative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... to Develop Data-Derived Extrapolation Factors for Interspecies and Intraspecies Extrapolation... Review Draft of ``Guidance for Applying Quantitative Data to Develop Data-Derived Extrapolation Factors... and to provide information to the regulated community and other interested parties about deriving...

  19. Metabolically-Derived Human Ventilation Rates: A Revised Approach Based Upon Oxygen Consumption Rates (External Review Draft)

    EPA Science Inventory

    EPA has released a draft report entitled, Metabolically-Derived Human Ventilation Rates: A Revised Approach Based Upon Oxygen Consumption Rates, for independent external peer review and public comment. NCEA published the Exposure Factors Handbook in 1997. This comprehens...

  20. 77 FR 12836 - Draft Toxicological Review of Biphenyl: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... Biphenyl: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R... of Summary Information on the Integrated Risk Information System (IRIS)'' is available primarily via... AGENCY Draft Toxicological Review of Biphenyl: In Support of Summary Information on the Integrated...

  1. 75 FR 59716 - Draft Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ... Urea: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' [EPA/ 635/R... AGENCY Draft Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of public...

  2. 75 FR 1617 - Draft Toxicological Review of Methanol: In Support of the Summary Information in the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R-09/013). The... AGENCY Draft Toxicological Review of Methanol: In Support of the Summary Information in the Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of...

  3. 76 FR 54227 - Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ...-Butanol: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/ 635/R... Integrated Risk Information System (IRIS)'' is available primarily via the Internet on the NCEA home page... AGENCY Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated...

  4. 78 FR 63464 - Notice of Extension of the Public Comment Period on the Draft Toxicological Review of Benzo[a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ...: In Support of the Summary Information on the Integrated Risk Information System (IRIS) and the... Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R-13/138) and the draft peer review... Web site is an ``anonymous access'' system, which means EPA will not know your identity or...

  5. 76 FR 71029 - Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R-11/081A). On... Integrated Risk Information System (IRIS)'' is available primarily via the Internet on the NCEA home page... AGENCY Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated...

  6. 76 FR 60827 - Draft Toxicological Review of Biphenyl: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... Biphenyl: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/ 635/R... Integrated Risk Information System (IRIS)'' is available primarily via the Internet on the NCEA home page... AGENCY Draft Toxicological Review of Biphenyl: In Support of Summary Information on the Integrated...

  7. 76 FR 57739 - Draft Toxicological Review of 1,4-Dioxane: In Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ...-Dioxane: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R...,4-Dioxane: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is... AGENCY Draft Toxicological Review of 1,4-Dioxane: In Support of Summary Information on the...

  8. Questions to Consider When Reviewing Draft WIOA State Plans. WIOA Game Plan for Low-Income People

    ERIC Educational Resources Information Center

    Center for Law and Social Policy, Inc. (CLASP), 2016

    2016-01-01

    As states release draft Workforce Innovation and Opportunity Act (WIOA) state plans for public comment, advocates and other stakeholders have an important opportunity to improve them. The Center for Law and Social Policy (CLASP) is offering a list of questions, which is included in this document, to consider when reviewing state plans. These…

  9. 78 FR 9387 - Notice of Availability for Public Review and Comment: Draft EPA Climate Change Adaptation Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-08

    ... AGENCY Notice of Availability for Public Review and Comment: Draft EPA Climate Change Adaptation Plan... that the climate is changing at an increasingly rapid rate, outside the range to which society has adapted in the past. Climate change can pose significant challenges to the EPA's ability to fulfill...

  10. 76 FR 55384 - External Peer Review Meeting for the Draft Guidance of Applying Quantitative Data To Develop Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ... AGENCY External Peer Review Meeting for the Draft Guidance of Applying Quantitative Data To Develop Data... Protection Agency (EPA). ACTION: Notice. SUMMARY: EPA is announcing that Eastern Research Group, Inc. (ERG..., ``Guidance for Applying Quantitative Data to Develop Data-Derived Extrapolation Factors for Interspecies...

  11. 77 FR 76000 - Notice of Availability of Draft Report of the NOAA Research and Development Portfolio Review Task...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... National Oceanic and Atmospheric Administration (NOAA), Science Advisory Board RIN 0648-XC378 Notice of Availability of Draft Report of the NOAA Research and Development Portfolio Review Task Force and Request for... Administration (NOAA), Department of Commerce (DOC). ACTION: Notice of availability and request for...

  12. 75 FR 71701 - Science Advisory Board Staff Office; Request for Nominations of Experts for the Review of a Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... AGENCY Science Advisory Board Staff Office; Request for Nominations of Experts for the Review of a Draft... Protection Agency (EPA). ACTION: Notice. SUMMARY: The EPA Science Advisory Board (SAB) Staff Office is...-2098, or via e-mail at carpenter.thomas@epa.gov . General information concerning the EPA...

  13. Watershed Modeling to Assess the Sensitivity of Streamflow, Nutrient, and Sediment Loads to Potential Climate Change and Urban Development in 20 U.S. Watersheds (External Review Draft)

    EPA Science Inventory

    EPA has released for independent external peer review and public comment a draft report titled, Watershed Modeling to Assess the Sensitivity of Streamflow, Nutrient, and Sediment Loads to Potential Climate Change and Urban Development in 20 U.S. Watersheds. This is a draft...

  14. 2012 DOE Vehicle Technologies Program Annual Merit Review

    SciTech Connect

    2012-10-26

    The 2012 DOE Hydrogen Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting was held May 14-18, 2012 in Crystal City, Virginia. The review encompassed all of the work done by the Hydrogen Program and the Vehicle Technologies Program: a total of 309 individual activities were reviewed for Vehicle Technologies, by a total of 189 reviewers. A total of 1,473 individual review responses were received for the technical reviews.

  15. IRIS Toxicological Review of Benzo[a]pyrene (External Review Draft)

    EPA Science Inventory

    The IRIS Toxicological Review of Benzo[a]pyrene was released for external peer review in September 2014. The EPA’s Science Advisory Board’s (SAB) Chemical Assessment Advisory Committee (CAAC) conducted a peer review of the scientific basis supporting the benzo[a]pyrene assessmen...

  16. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 3: Space power and thermal management

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Viewgraphs of briefings from the SSTAC/ARTS review of the draft integrated technology plan on thermal power and thermal management are presented. Topics covered include: space energy conversion research and technology; space photovoltaic energy conversion; chemical energy conversion and storage; thermal energy conversion; power management; thermal management; space nuclear power; high capacity power; surface power and thermal management; space platforms power and thermal management; and project SELENE.

  17. Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (Revised July 2013 External Review Draft) (Public Comment Draft)

    EPA Science Inventory

    EPA is initiating a public comment period prior to peer review of the scientific basis supporting the human health hazard and dose-response assessment of ethylene oxide (cancer) that will appear in the Integrated Risk Information System (IRIS) database.

  18. IRIS Toxicological Review of Dibutyl Phthalate (DBP) (External Review Draft) 2006

    EPA Science Inventory

    The U.S. EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of dibutyl phthalate that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used cr...

  19. IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR 1,1,1-TRICHLOROETHANE (EXTERNAL REVIEW DRAFT)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,1,1-trichloroethane that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibl...

  20. IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR 2,2,4-TRIMETHYLPENTANE (EXTERNAL REVIEW DRAFT)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 2,2,4-trimethylpentane, also called TMP, that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that scie...

  1. IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR BORON AND COMPOUNDS (THIRD EXTERNAL REVIEW DRAFT 2002)

    EPA Science Inventory

    The U. S. EPA has conducted a peer review of the scientific basis supporting the health hazard and dose response assessment for Boron that will appear on the Agency's online data base, the Integrated Risk Information System (IRIS). Peer Review is meant to ensure that science is u...

  2. IRIS Toxicological Review of 1,2,3-Trichloropropane (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,2,3-trichloropropane (TCP) that once finalized will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that scie...

  3. A Review of the Impact of Climate Variability and Change on Aeroallergens and Their Associated Effects on Human Morbidity and Mortality in the U.S. (External Review Draft)

    EPA Science Inventory

    EPA has released for public comment a draft report entitled, A Review of the Impact of Climate Variability and Change on Aeroallergens and their Associated Effects. This draft report is a survey of the current state of scientific knowledge of the potential impacts of clim...

  4. 2015 DOE Vehicle Technologies Office Annual Merit Review

    SciTech Connect

    None, None

    2015-11-01

    The 2015 U.S. Department of Energy (DOE) Fuel Cell Technologies Office (FCTO) and Vehicle Technologies Office (VTO) Annual Merit Review and Peer Evaluation Meeting (AMR) was held June 8-12, 2015, in Arlington, Virginia. The review encompassed all of the work done by the FCTO and the VTO: 258 individual activities were reviewed for VTO, by 170 reviewers. A total of 1,095 individual review responses were received for the VTO technical reviews. The objective of the meeting was to review the accomplishments and plans for VTO over the previous 12 months, and provide an opportunity for industry, government, and academia to give inputs to DOE on the Office with a structured and formal methodology. The meeting also provided attendees with a forum for interaction and technology information transfer.

  5. 2014 DOE Vehicle Technologies Office Annual Merit Review

    SciTech Connect

    2014-11-01

    The 2014 U.S. Department of Energy (DOE) Fuel Cell Technologies Office (FCTO) and Vehicle Technologies Office (VTO) Annual Merit Review and Peer Evaluation Meeting (AMR) was held June 16-20, 2014, in Washington, DC. The review encompassed all of the work done by the FCTO and the VTO: a total of 295 individual activities were reviewed for VTO, by a total of 179 reviewers. A total of 1,354 individual review responses were received for the VTO technical reviews. The objective of the meeting was to review the accomplishments and plans for VTO over the previous 12 months, and provide an opportunity for industry, government, and academia to give inputs to DOE on the Office with a structured and formal methodology. The meeting also provided attendees with a forum for interaction and technology information transfer.

  6. 2013 DOE Vehicle Technologies Office Annual Merit Review

    SciTech Connect

    none,

    2013-10-01

    The 2013 U.S. Department of Energy (DOE) Fuel Cell Technologies Office (FCTO) and Vehicle Technologies Office (VTO) Annual Merit Review and Peer Evaluation Meeting (AMR) was held May 13-17, 2013, in Crystal City, Virginia. The review encompassed all of the work done by the FCTO and the VTO: a total of 287 individual activities were reviewed for VTO, by a total of 187 reviewers. A total of 1,382 individual review responses were received for the VTO technical reviews. The objective of the meeting was to review the accomplishments and plans for VTO over the previous 12 months, and provide an opportunity for industry, government, and academia to give inputs to DOE on the Office with a structured and formal methodology. The meeting also provided attendees with a forum for interaction and technology information transfer.

  7. 76 FR 70151 - Draft Guidance for Industry, Clinical Investigators, Institutional Review Boards, and Food and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry, Clinical Investigators... determined, despite outstanding issues, that the information provided is sufficient to justify human clinical... maintaining appropriate subject protections. Staged approval or staged approval with conditions is most...

  8. 75 FR 51838 - Public Review of Draft Coastal and Marine Ecological Classification Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... and Marine Ecological Classification Standard AGENCY: Department of the Interior, U.S. Geological Survey. ACTION: Notice; request for comments on draft Coastal and Marine Ecological Classification... Coastal and Marine Ecological Classification Standard (CMECS). CMECS provides a means of...

  9. IRIS Toxicological Review of Cis-& Trans-1,2-Dichloroethylene (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of cis- and trans-1,2-dichloroethylene that will appear in the Integrated Risk Information System (IRIS) database.

  10. IRIS Toxicological Review of Ethylene Glycol Mono-Butyl Ether (Egbe) (External Review Draft)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of ethylene glycol monobutyl ether that will appear on the Integrated Risk Information System (IRIS) database.

  11. IRIS Toxicological Review of 1,1,2,2-Tetrachloroethane (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,1,2,2-tetrachloroethane that will appear on the Integrated Risk Information System (IRIS) database.

  12. IRIS Toxicological Review of Beryllium and Compounds (2008 External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Beryllium that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  13. IRIS Toxicological Review of Cerium Oxide and Cerium Compounds (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of cerium oxide and cerium compounds that will appear on the Integrated Risk Information System (IRIS) database.

  14. 2009 DOE Vehicle Technologies Program Annual Merit Review

    SciTech Connect

    none,

    2009-10-01

    Annual Merit Review and Peer Evaluation Meeting to review the FY2008 accomplishments and FY2009 plans for the Vehicle Technologies Program, and provide an opportunity for industry, government, and academic to give inputs to DOE on the Program with a structured and formal methodology.

  15. Comments on the Draft Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System

    EPA Pesticide Factsheets

    Comments from the members of the SAB Arsenic Review Panel on the draft Toxicological Review of Inorganic Arsenic in Support of Summary Information on the Integrated Risk Information System (IRIS) document that will be review by a Work Group of the Chartered SAB.

  16. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (Etbe) (External Review Draft, 2009)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of ethyl tertiary butyl ether (ETBE) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  17. IRIS Toxicological Review of Methanol (Non-Cancer) (External Review Draft; April 2011)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of methanol (non-cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  18. IRIS Toxicological Review of 1,4-Dioxane (External Review Draft, 2009)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of 1,4-dioxane that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  19. IRIS Toxicological Review of Inorganic Arsenic (Cancer) (2010 External Review Draft)

    EPA Science Inventory

    EPA's Science Advisory Board (SAB) conducted a review of the scientific basis supporting the human health cancer hazard and dose-response assessment of inorganic arsenic that will appear on the Integrated Risk Information System (IRIS) database. EPA revised the assessment and is...

  20. Toxicological Review of Cyanobacterial Toxins: Microcystins Lr, Rr, Yr and La (External Review Draft)

    EPA Science Inventory

    The National Center for Environmental Assessment has prepared the Toxicological Reviews of Cyanobacterial Toxins: Anatoxin-a, Cylindrospermopsin and Microcystins (LR, RR, YR and LA) as a series of dose-response assessments to support the health assessment of unregulated contamina...

  1. Toxicological Review of Cyanobacterial Toxins: Anatoxin-a (External Review Draft)

    EPA Science Inventory

    The National Center for Environmental Assessment has prepared the Toxicological Reviews of Cyanobacterial Toxins: Anatoxin-a, Cylindrospermopsin and Microcystins (LR, RR, YR and LA) as a series of dose-response assessments to support the health assessment of unregulated contamina...

  2. Summary of DOE/PERF water program review.

    SciTech Connect

    Veil, J.; Gasper, J.; Puder, M.; Leath, P.; Environmental Science Division

    2006-01-31

    For many years, the U.S. Department of Energy (DOE) has supported and sponsored various types of water research relating to the oil and gas industry through its Office of Fossil Energy and its National Energy Technology Laboratory (NETL). In early 2005, the Petroleum Environmental Research Forum (PERF) submitted a proposal to DOE for funding an upcoming PERF meeting that would feature water research in the petroleum industry. PERF is a nonprofit organization created in 1986 to provide a stimulus to and a forum for the collection, exchange, and analysis of research information related to the development of technology concerning the petroleum industry, and a mechanism for establishing joint research projects in that field. Additional information on PERF can be accessed at http://www.perf.org. DOE agreed to provide funding to hold a review of its water research program in conjunction with the fall 2005 PERF meeting. Argonne National Laboratory (Argonne) was asked to coordinate and host the meeting, which was referred to as the DOE/PERF Water Program Review. The program review was held on November 1-4, 2005, in Annapolis, Maryland, at the Historic Inns of Annapolis. The purpose of the program review was to provide a forum for sharing information, reviewing current programs (especially recent unpublished research), and reviewing industry and regulatory needs regarding water use and reuse issues. PERF and DOE/NETL can use this information to plan for future water-related research projects. The water program review provided a unique opportunity in several ways. First, DOE was able to have all of the contractors currently receiving DOE funds for water research present in one room at the same time. Each contractor described his or her research and was able to learn about the research being conducted by the other researchers. Second, this forum allowed representatives of many large oil and gas companies to hear about the DOE research projects and offer their reactions to DOE

  3. Does sunlight prevent cancer? A systematic review.

    PubMed

    van der Rhee, H J; de Vries, E; Coebergh, J W W

    2006-09-01

    Accumulating evidence for beneficial effects of sunlight on several types of cancer with a high mortality rate makes it necessary to reconsider the health recommendations on sun exposure, which are now mainly based on the increased risks for skin cancer. We reviewed all published studies concerning sun exposure and cancer, excluding skin cancer. All selected studies on prostate (3 ecologic, 3 case-control and 2 cohort), breast (4 ecologic, 1 case-control and 2 cohort) and ovary cancer (2 ecologic and 1 case-control) showed a significantly inverse correlation between sunlight and mortality or incidence. Two ecologic, 1 case-control and 2 prospective studies showed an inverse relation between sunlight and colon cancer mortality; 1 case-control study found no such association. Ecologic studies on non-Hodgkin lymphoma (NHL) mortality and sunlight gave conflicting results: early studies showing mostly positive and later studies showing mostly negative correlations. Three case-control studies and 1 cohort study found a significant inverse association between the incidence of NHL and sunlight. The question of how to apply these findings to (public) health recommendations is discussed.

  4. 77 FR 69619 - Draft Recommendations of Joint Outreach Team

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

    ... Area Power Administration Draft Recommendations of Joint Outreach Team AGENCY: Western Area Power Administration, DOE. ACTION: Notice of Availability of draft recommendations of Western/DOE Joint Outreach Team... Department of Energy (DOE), is publishing the draft recommendations of the Western/DOE Joint Outreach...

  5. RE:RE: Comments on the Draft US EPA Document Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS).

    EPA Pesticide Factsheets

    Letter from the Organic Arsenical Products Task Force expressing concern about aspects of the Science Advisory Board Workgroup's review of a draft document Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS) and decision not to grant more time to prepare for meeting.

  6. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (Second External Review Draft, Dec 2016)

    EPA Science Inventory

    This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of sulfur oxides. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current primar...

  7. Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria (Second External Review Draft, 2015)

    EPA Science Inventory

    This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of oxides of nitrogen. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current ...

  8. 76 FR 67439 - External Peer Review Meeting for Draft Microbial Risk Assessment Guideline: Pathogenic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... Microorganisms With Focus on Food and Water AGENCY: Environmental Protection Agency (EPA). ACTION: Notice...: Pathogenic Microorganisms with Focus on Food and Water. EPA previously announced the release of the draft... Guideline: Pathogenic Microorganisms with Focus on Food and Water will be held on Monday, November 7,...

  9. Nanomaterial Case Study: Nanoscale Silver in Disinfectant Spray (External Review Draft)

    EPA Science Inventory

    This draft document presents a case study of engineered nanoscale silver (nano-Ag), focusing on the specific example of nano-Ag as possibly used in disinfectant sprays. This case study is organized around a comprehensive environmental assessment (CEA) framework, which combines a ...

  10. Climate Change Effects on Stream and River Biological Indicators: A Preliminary Analysis (External Review Draft)

    EPA Science Inventory

    This draft report is a preliminary assessment that describes how biological indicators are likely to respond to climate change, how well current sampling schemes may detect climate-driven changes, and how likely it is that these sampling schemes will continue to detect impairment...

  11. 75 FR 16837 - Public Review of Draft United States Thoroughfare, Landmark, and Postal Address Data Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... exchange, and data quality. The Urban and Regional Information Systems Association (URISA), in conjunction... Address Data Standard AGENCY: Department of the Interior, U.S. Geological Survey. ACTION: Notice; request for comments on draft United States Thoroughfare, Landmark, and Postal Address Data Standard...

  12. BASINS and WEPP Climate Assessment Tools (CAT): Case Study Guide to Potential Applications (External Review Draft)

    EPA Science Inventory

    This draft report supports application of two recently developed water modeling tools, the BASINS and WEPP climate assessment tools. The report presents a series of short case studies designed to illustrate the capabilities of these tools for conducting scenario based assessments...

  13. Integrated Science Assessment for Oxides of Nitrogen – Health Criteria (Second External Review Draft, 2015)

    EPA Science Inventory

    This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of oxides of nitrogen. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current ...

  14. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (Second External Review Draft)

    EPA Science Inventory

    This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of sulfur oxides. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current primar...

  15. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (External Review Draft)

    EPA Science Inventory

    This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of sulfur oxides. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current primar...

  16. 78 FR 65622 - Notice of Availability for the Draft Environmental Impact Statement and Announcement of Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... the Proposed Champlain Hudson Power Express Transmission Line Project AGENCY: U.S. Department of...) announces the availability of the ``Draft Environmental Impact Statement for the Champlain Hudson Power Express Transmission Line Project'' (DOE/EIS-0447) for public review and comment. DOE is also...

  17. Connectivity of Streams and Wetlands to Downstream Waters: A Review and Synthesis of the Scientific Evidence (External Review Draft)

    EPA Science Inventory

    The Environmental Protection Agency – through the independent Scientific Advisory Board (SAB) - is soliciting public comment on a new draft science report titled: Connectivity of Streams and Wetlands to Downstream Waters. A public docket has been opened to receive com...

  18. Multitarget stool DNA for colorectal cancer screening: A review and commentary on the United States Preventive Services Draft Guidelines

    PubMed Central

    Berger, Barry M; Levin, Bernard; Hilsden, Robert J

    2016-01-01

    Multitarget stool DNA (mt-sDNA) testing was approved for average risk colorectal cancer (CRC) screening by the United States Food and Drug Administration and thereafter reimbursed for use by the Medicare program (2014). The United States Preventive Services Task Force (USPSTF) October 2015 draft recommendation for CRC screening included mt-sDNA as an “alternative” screening test that “may be useful in select clinical circumstances”, despite its very high sensitivity for early stage CRC. The evidence supporting mt-sDNA for routine screening use is robust. The clinical efficacy of mt-sDNA as measured by sensitivity, specificity, life-years gained (LYG), and CRC deaths averted is similar to or exceeds that of the other more specifically recommended screening options included in the draft document, especially those requiring annual testing adherence. In a population with primarily irregular screening participation, tests with the highest point sensitivity and reasonable specificity are more likely to favorably impact CRC related morbidity and mortality than those depending on annual adherence. This paper reviews the evidence supporting mt-sDNA for routine screening and demonstrates, using USPSTF’s modeling data, that mt-sDNA at three-year intervals provides significant clinical net benefits and fewer complications per LYG than annual fecal immunochemical testing, high sensitivity guaiac based fecal occult blood testing and 10-year colonoscopy screening. PMID:27190584

  19. Exposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (Tcdd) and Related Compounds: Science Advisory Board (External Review Draft) (2000)

    EPA Science Inventory

    Dioxin Reassessment, SAB Review Draft

    The U.S. Environmental Protection Agency's (EPA) is progressing toward completion of its comprehensive reassessment of dioxin science entitled, "Exposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibe...

  20. Nanomaterial Case Study: A Comparison of Multiwalled Carbon Nanotube and Decabromodiphenyl Ether Flame-Retardant Coatings Applied to Upholstery Textiles (Independent Peer Review Draft)

    EPA Science Inventory

    This Independent Peer Review Draft document presents a case study of multiwalled carbon nanotubes (MWCNTs); it focuses on the specific example of MWCNTs as used in flame-retardant coatings applied to upholstery textiles. This case study is organized around the comprehensive envir...

  1. An Assessment of Decision-Making Processes: The Feasibility of Incorporating Climate Change Information into Land Protection Planning (External Review Draft)

    EPA Science Inventory

    This report was prepared by the Global Change Research Program (GCRP) in the National Center for Environmental Assessment (NCEA) of the Office of Research and Development (ORD) at the U.S. Environmental Protection Agency (EPA). This draft report is a review of decision-making pro...

  2. Drafting human ancestry: what does the Neanderthal genome tell us about hominid evolution? Commentary on Green et al. (2010).

    PubMed

    Hofreiter, Michael

    2011-02-01

    Ten years after the first draft versions of the human genome were announced, technical progress in both DNA sequencing and ancient DNA analyses has allowed a research team around Ed Green and Svante Pääbo to complete this task from infinitely more difficult hominid samples: a few pieces of bone originating from our closest, albeit extinct, relatives, the Neanderthals. Pulling the Neanderthal sequences out of a sea of contaminating environmental DNA impregnating the bones and at the same time avoiding the problems of contamination with modern human DNA is in itself a remarkable accomplishment. However, the crucial question in the long run is, what can we learn from such genomic data about hominid evolution?

  3. Review of ''Draft - Area Recommendation Report for the Crystalline Repository Project'', January 1986. [Rolesville pluton and Elk River complex

    SciTech Connect

    Butler, J.R.

    1986-03-13

    The Draft-Area Recommendation Report identifies portions of crystalline rock bodies as proposed potentially acceptable sites for consideration as repositories of high-level radioactive waste. The review is in three parts. Part I is a general summary of the main comments, written in semi-technical language and without detailed documentation or references. It includes summaries of comments on the two preliminary candidate areas for a nuclear-waste repository in North Carolina (Rolesville pluton and Elk River complex) and on the rest of the report. The following two parts are written in the technical language of a geological report and include both documentation and references for each of the points discussed: Part II - Rolesville pluton, Site SE-4; Part III - Elk River complex, Site SE-5.

  4. A national program for energy-efficient mortgages and home energy rating systems: A blueprint for action. Review draft

    SciTech Connect

    Not Available

    1992-03-01

    This Review Draft reports findings and recommendations of the National Collaborative on Home Energy Rating Systems and Mortgage Incentives for Energy Efficiency. The US Department of Energy, in cooperation with the US Department of Housing and Urban Development, formed this National Collaborative as a National Energy Strategy initiative. Participating in the Collaborative were representatives of the primary and secondary mortgage markets, builder and remodeler organizations, real estate and appraiser associations, the home energy rating system industry, utility associations, consumer and public interest groups, state and local government interest groups, and environmental organizations. The Collaborative`s purpose was to develop a voluntary national program encouraging energy efficiency in homes through mortgage incentives linked to home energy ratings.

  5. 1992 DOE/Sandia crystalline photovoltaic technology project review meeting

    SciTech Connect

    Maish, A.

    1992-07-01

    This document serves as the proceedings for the annual project review meeting held by Sandia National Laboratories` Photovoltaic Technology and Photovoltaic Evaluation Departments. It contains information supplied by organizations making presentations at the meeting, which was held July 14--15, 1992 at the Sheraton Old Town Hotel in Albuquerque, New Mexico. Overview sessions covered the Department of Energy (DOE) program, including those at Sandia and the National Renewable Energy Laboratory (NREL), and non-DOE programs, including the EPRI concentrator collector program, The Japanese crystalline silicon program, and some concentrating photovoltaic activities in Europe. Additional sessions included papers on Sandia`s Photovoltaic Device Fabrication Laboratory`s collaborative research, cell processing research, the activities of the participants in the Concentrator Initiative Program, and photovoltaic technology evaluation at Sandia and NREL.

  6. IRIS Toxicological Review of cis- & trans-1,2-Dichloroethylene (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 24, 2009, the Toxicological Review of cis- and trans-1,2-dichloroethylene and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal ag...

  7. 76 FR 77492 - Draft Guidance on Improving the Process for Preparing Efficient and Timely Environmental Reviews...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... review and keeping in mind the following basic principles: (1) NEPA encourages simple, straightforward...) NEPA reviews should coordinate and take appropriate advantage of existing documents and studies... reviews should coordinate and take appropriate advantage of existing documents and studies,...

  8. Radioactive waste isolation in salt: Peer review of the Golder Associates draft test plan for in situ testing in an exploratory shaft in salt

    SciTech Connect

    Hambley, D.F.; Mraz, D.Z.; Unterberter, R.R.; Stormont, J.C.; Neuman, S.P.; Russell, J.E.; Jacoby, C.H.; Hull, A.B.; Brady, B.H.G.; Ditmars, J.D.

    1987-01-01

    This report documents the peer review conducted by Argonne National Laboratory of a document entitled ''Draft Test Plan for In Situ Testing in an Exploratory Shaft in Salt,'' prepared for Battelle Memorial Institute's Office of Nuclear Waste Isolation by Golder Associates, Inc. In general, the peer review panelists found the test plan to be technically sound, although some deficiencies were identified. Recommendations for improving the test plan are presented in this review report. A microfiche copy of the following unpublished report is attached to the inside back cover of this report: ''Draft Test Plan for In Situ Testing in an Exploratory Shaft in Salt,'' prepared by Golder Associates, Inc., for Office of Nuclear Waste Isolation, Battelle Memorial Institute, Columbus, Ohio (March 1985).

  9. Architectural Drafting.

    ERIC Educational Resources Information Center

    Davis, Ronald; Yancey, Bruce

    Designed to be used as a supplement to a two-book course in basic drafting, these instructional materials consisting of 14 units cover the process of drawing all working drawings necessary for residential buildings. The following topics are covered in the individual units: introduction to architectural drafting, lettering and tools, site…

  10. Mechanical Drafting.

    ERIC Educational Resources Information Center

    McClain, Gerald R.

    This publication, the third in a series on drafting, is intended to strengthen students' competence in the specialized field of mechanical drafting. The text consists of instructional materials for both teacher and students, written in terms of student performance using measurable objectives. The course includes 11 units. Each instructional unit…

  11. 75 FR 57776 - Clean Water Act Section 303(d): Notice for the Public Review of the Draft Total Maximum Daily...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... notice announces the availability of EPA's Draft Chesapeake Bay (Bay) TMDL for nutrients and sediment for... held within the watershed. EPA is establishing the Draft TMDL for nutrients (nitrogen and phosphorus... standards. The pollutants that are largely responsible for impairment of the Chesapeake Bay are...

  12. 76 FR 33752 - Notice of Availability of the External Review Draft of the Guidance for Applying Quantitative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... To Develop Data-Derived Extrapolation Factors for Interspecies and Intraspecies Extrapolation AGENCY... Draft of ``Guidance for Applying Quantitative Data to Develop Data-Derived Extrapolation Factors for... information below. This draft Guidance for Data Derived Extrapolation Factors document outlines approaches...

  13. The draft FDA guideline on non-inferiority clinical trials: a critical review from European pharmaceutical industry statisticians.

    PubMed

    Huitfeldt, Bernhard; Hummel, Jürgen

    2011-01-01

    The European Federation of Statisticians in the Pharmaceutical Industry (EFSPI) engages more than 2000 statisticians through its ten national organizations. Amongst other things, EFSPI is involved in reviewing regulatory guidelines under development, including the draft FDA guideline on non-inferiority clinical trials. This review resulted in several critical comments relating to as follows: (i) the lack of one single standard for proving efficacy of new drugs implied by the guideline; (ii) the problems with the suggested 'fraction of effect to be preserved'; (iii) the formulation of the primary hypothesis in a non-inferiority trial aiming at indirectly demonstrating a new drug is superior to placebo; and (iv) the preference in the guideline for the fixed-margin method over the synthesis method in the analysis. The presumed implications of this guideline, if implemented as is, are (i) increased confusion of how efficacy could be demonstrated when placebo control is not available, (ii) more complicated communication between pharmaceutical industry and FDA because of the apparent disagreements on fundamental statistical matters, and (iii) illogical consequences in the approval process because of which order drugs are approved rather than how they fulfill the regulatory requirements. We believe that the area is not yet ready for such a prescriptive regulatory guidance and that further research and experience are required until the methodology can be finally agreed. A strategy needs to be developed by regulatory agencies together with drug industry and academia for a long term solution for this topic.

  14. 77 FR 69631 - Draft Guidance for IRBs, Clinical Investigators, and Sponsors: IRB Responsibilities for Reviewing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

    ... Responsibilities for Reviewing the Qualifications of Investigators, Adequacy of Research Sites, and the... of investigators, adequacy of research sites, and the determination of whether an investigational new... Responsibilities for Reviewing the Qualifications of Investigators, Adequacy of Research Sites, and...

  15. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 8: Aerothermodynamics Automation and Robotics (A/R) systems sensors, high-temperature superconductivity

    SciTech Connect

    Not Available

    1991-06-01

    Viewgraphs of briefings presented at the SSTAC/ARTS review of the draft Integrated Technology Plan (ITP) on aerothermodynamics, automation and robotics systems, sensors, and high-temperature superconductivity are included. Topics covered include: aerothermodynamics; aerobraking; aeroassist flight experiment; entry technology for probes and penetrators; automation and robotics; artificial intelligence; NASA telerobotics program; planetary rover program; science sensor technology; direct detector; submillimeter sensors; laser sensors; passive microwave sensing; active microwave sensing; sensor electronics; sensor optics; coolers and cryogenics; and high temperature superconductivity.

  16. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 8: Aerothermodynamics Automation and Robotics (A/R) systems sensors, high-temperature superconductivity

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Viewgraphs of briefings presented at the SSTAC/ARTS review of the draft Integrated Technology Plan (ITP) on aerothermodynamics, automation and robotics systems, sensors, and high-temperature superconductivity are included. Topics covered include: aerothermodynamics; aerobraking; aeroassist flight experiment; entry technology for probes and penetrators; automation and robotics; artificial intelligence; NASA telerobotics program; planetary rover program; science sensor technology; direct detector; submillimeter sensors; laser sensors; passive microwave sensing; active microwave sensing; sensor electronics; sensor optics; coolers and cryogenics; and high temperature superconductivity.

  17. 76 FR 36094 - Draft NOAA Scientific Integrity Policy and Handbook; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... National Oceanic and Atmospheric Administration Draft NOAA Scientific Integrity Policy and Handbook... Administration (NOAA), Department of Commerce (DOC). ACTION: Draft NOAA Scientific Integrity Policy and Handbook for Public Review. SUMMARY: NOAA's draft scientific integrity policy is available for public...

  18. Proceedings of the 1993 DOE/NREL Hydrogen Program Review

    SciTech Connect

    Not Available

    1993-08-01

    The US Department of Energy has conducted programs of research and development in hydrogen and related technologies since 1975. The current program is conducted in accordance with the DOE Hydrogen Program Plan FY 1993--FY 1997 which was published in June 1992. The plan establishes program priorities and guidance for the allocation of funding. The core program. currently under the Office of Energy Management, supports projects in the areas of hydrogen production, storage and systems research. A program review is held annually to evaluate each research project for technical quality, progress and programmatic benefit. The evaluation is conducted by a panel of technical experts. This proceedings of the Program Review conducted in May 1993 is a compilation of all research projects supported by the Hydrogen Program during FY 1993. It is produced in the anticipation that will serve as a useful technical reference for those interested in the status of hydrogen technologies. Selected papers have been indexed separately for inclusion in the Energy Science and Technology Database.

  19. IRIS Toxicological Review of Benzo[a]pyrene (Interagency Science Discussion Draft)

    EPA Science Inventory

    In January 2017, EPA finalized the IRIS assessment of Benzo[a]pyrene. The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written...

  20. IRIS Toxicological Review of Ammonia Noncancer Inhalation (Interagency Science Discussion Draft)

    EPA Science Inventory

    In September 2016, EPA finalized the IRIS assessment of Ammonia (Noncancer Inhalation). The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices before public release in June 2016. Consistent with the May 2009 IRIS assessment d...

  1. 34 CFR 222.159 - When and where does a party seek judicial review?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false When and where does a party seek judicial review? 222... Hearings and Judicial Review Under Section 8011 of the Act § 222.159 When and where does a party seek... administrative hearing proceeding under this subpart wishes to seek judicial review, the LEA or State...

  2. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (Rdx) (External Review Draft)

    EPA Science Inventory

    The IRIS Toxicological Review of Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) was released for external peer review in September 2016. The EPA’s Science Advisory Board’s (SAB) Chemical Assessment Advisory Committee (CAAC) will conduct a peer review of the scientific basis suppor...

  3. 76 FR 58311 - Draft License Renewal Interim Staff Guidance LR-ISG-2011-05; Ongoing Review of Operating Experience

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... request from the Nuclear Energy Institute (NEI), the NRC is extending the public comment period until... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY... Experience AGENCY: Nuclear Regulatory Commission. ACTION: Draft interim staff guidance; extension of...

  4. Aquatic Ecosystems, Water Quality, and Global Change: Challenges of conducting Multi-Stressor Vulnerability Assessments (External Review Draft)

    EPA Science Inventory

    This draft report investigates the issues and challenges associated with identifying, calculating, and mapping indicators of the relative vulnerability of water quality and aquatic ecosystems, across the United States, to the potential impacts of global change. Using a large set...

  5. Climate and Land Use Change Effects on Ecological Resources in Three Watersheds: A Synthesis Report (External Review Draft)

    EPA Science Inventory

    The purpose of this draft report is to provide a summary of climate change impacts to selected watersheds and recommendations for how to improve the process of conducting watershed assessments in the future.

  6. Evaluation of the Carcinogenicity of Ethylene Oxide (2006 External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of ethylene oxide (cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  7. 75 FR 69064 - Draft Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of... Summary Information on the Integrated Risk Information System (IRIS)'' is available primarily via the..., ``Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the Integrated...

  8. AIR QUALITY CRITERIA FOR LEAD, VOLUMES 1-4. (1983) FIRST EXTERNAL REVIEW DRAFT

    EPA Science Inventory

    The document evaluates and assesses scientific information on the health and welfare effects associated with exposure to various concentrations of lead in ambient air. The literature through 1983 has been reviewed thoroughly for information relevant to air quality criteria, altho...

  9. Radioactive waste isolation in salt: Peer review of the Office of Nuclear Waste Isolation's draft report on an issues hierarchy and data needs for site characterization

    SciTech Connect

    Harrison, W.; Fenster, D.F.; Ditmars, J.D.; Paddock, R.A.; Rote, D.M.; Hambley, D.F.; Seitz, M.G.; Hull, A.B.

    1986-12-01

    At the request of the Salt Repository Project (SRPO), Argonne National Laboratory conducted an independent peer review of a report by the Battelle Office of Nuclear Waste Isolation entitled ''Salt Repository Project Issues Hierarchy and Data Needs for Site Characterization (Draft).'' This report provided a logical structure for evaluating the outstanding questions (issues) related to selection and licensing of a site as a high-level waste repository. It also provided a first estimate of the information and data necessary to answer or resolve those questions. As such, this report is the first step in developing a strategy for site characterization. Microfiche copies of ''Draft Issues Hierarchy, Resolution Strategy, and Information Needs for Site Characterization and Environmental/Socioeconomic Evaluation - July, 1986'' and ''Issues Hierarchy and Data Needs for Site Characterization - February, 1985'' are included in the back pocket of this report.

  10. Review of the WIPP draft application to show compliance with EPA transuranic waste disposal standards

    SciTech Connect

    Neill, R.H.; Chaturvedi, L.; Clemo, T.M.

    1996-03-01

    The purpose of the New Mexico Environmental Evaluation Group (EEG) is to conduct an independent technical evaluation of the Waste Isolation Pilot Plant (WIPP) Project to ensure the protection of the public health and safety and the environment. The WIPP Project, located in southeastern New Mexico, is being constructed as a repository for the disposal of transuranic (TRU) radioactive wastes generated by the national defense programs. The EEG was established in 1978 with funds provided by the U.S. Department of Energy (DOE) to the State of New Mexico. Public Law 100-456, the National Defense Authorization Act, Fiscal Year 1989, Section 1433, assigned EEG to the New Mexico Institute of Mining and Technology and continued the original contract DE-AC04-79AL10752 through DOE contract DE-AC04-89AL58309. The National Defense Authorization Act for Fiscal Year 1994, Public Law 103-160, continues the authorization. EEG performs independent technical analyses of the suitability of the proposed site; the design of the repository, its planned operation, and its long-term integrity; suitability and safety of the transportation systems; suitability of the Waste Acceptance Criteria and the generator sites` compliance with them; and related subjects. These analyses include assessments of reports issued by the DOE and its contractors, other federal agencies and organizations, as they relate to the potential health, safety and environmental impacts from WIPP. Another important function of EEG is the independent environmental monitoring of background radioactivity in air, water, and soil, both on-site and off-site.

  11. 77 FR 70776 - Draft Integrated Science Assessment for Lead

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-27

    ... AGENCY Draft Integrated Science Assessment for Lead AGENCY: Environmental Protection Agency (EPA). ACTION..., ``Third External Review Draft Integrated Science Assessment for Lead'' (EPA/600/R-10/075C). The document... lead (Pb). EPA is releasing this draft document to seek review by the Clean Air Scientific...

  12. 77 FR 5247 - Draft Integrated Science Assessment for Lead

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... AGENCY Draft Integrated Science Assessment for Lead AGENCY: Environmental Protection Agency (EPA). ACTION..., ``Second External Review Draft Integrated Science Assessment for Lead'' (EPA/600/R-10/075B). The document... Review Draft Integrated Science Assessment for Lead'' will be available primarily via the Internet on...

  13. 76 FR 8741 - National Toxicology Program (NTP): Office of Liaison, Policy, and Review; Availability of Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ... at http://ntp.niehs.nih.gov/go/36051 ) that will be peer-reviewed by an NTP Technical Reports Peer... information, when available, will be posted on the NTP Web site ( http://ntp.niehs.nih.gov/go/36051 ) or may... NTP testing program is found at http://ntp.niehs.nih.gov/go/test . Attendance and Registration...

  14. 75 FR 73085 - National Toxicology Program (NTP): Office of Liaison, Policy, and Review; Availability of Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ...; available at http://ntp.niehs.nih.gov/go/36051 ) that will be peer-reviewed by an NTP Technical Reports Peer... site ( http://ntp.niehs.nih.gov/go/36051 ) or may be requested in hardcopy from the Designated Federal.../go/test . Attendance and Registration The meeting is scheduled for January 26, 2011, from 8:30...

  15. 75 FR 30825 - Draft Toxicological Review of Formaldehyde in Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... NAS peer review meetings, one or more NAS meetings may take place before the close of EPA's public... provide all public ] comments to the NAS at least 5 working days before the meeting date announced on the..., they should also submit written comments at least 5 working days before the meeting date announced...

  16. 78 FR 38315 - Registration Review; Draft Human Health and Ecological Risk Assessments; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the procedural regulations for registration review at.... The Agency has conducted a human health risk assessment for both dietary (food and drinking water) and... dietary (food and drinking water), residential and occupational exposure pathways. An addendum to the...

  17. 78 FR 27374 - Workshop To Review Initial Draft Materials for the Nitrogen Oxides (NOX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    .... SUMMARY: As part of the review of the air quality criteria for nitrogen oxides (NO X ) and primary (health-based) National Ambient Air Quality Standards (NAAQS) for nitrogen dioxide (NO 2 ), EPA is announcing a... observers on a first-come, first-served basis up to the limits of available space. DATES: The workshop...

  18. 75 FR 42085 - Workshop To Review Initial Health Effects Draft Materials for the Ozone (O3

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... of the review of the air quality criteria and National Ambient Air Quality Standard (NAAQS) for Ozone... observers on a first-come, first-served basis up to the limits of available space. DATES: The workshop will...) of the Clean Air Act requires the U.S. Environmental Protection Agency (EPA) to conduct...

  19. 75 FR 69078 - Workshop To Review Draft Materials for the Lead (Pb) Integrated Science Assessment (ISA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ...: Environmental Protection Agency (EPA). ACTION: Notice of Workshop. SUMMARY: As part of the review of the air quality criteria and National Ambient Air Quality Standards (NAAQS) for Lead (Pb), EPA is announcing that... the limits of available space. DATES: The workshop will be held on December 2 and 3, 2010 at 8...

  20. 75 FR 60454 - Draft Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-30

    ... Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of... Integrated Risk Information System (IRIS)'' is available primarily via the Internet on the NCEA home page..., ``Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the Integrated...

  1. 76 FR 20349 - Draft Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of... Chromium: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available..., ``Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the Integrated...

  2. 75 FR 73078 - Human Studies Review Board (HSRB); Notification of a Public Teleconference To Review Draft Report...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ... ``anonymous access'' system, which means EPA will not know your identity or contact information unless you... available on the Internet. I. General Information A. Does this action apply to me? This action is directed... Register document electronically through the EPA Internet under the Federal Register listings at...

  3. Human-system interface design review guideline: The development of draft revision 1 to NUREG-0700

    SciTech Connect

    O`Hara, J.; Stubler, W.; Brown, W.

    1996-03-01

    Advanced human-system interface (HSI) technologies are being developed in the commercial nuclear power industry. These HSIs may have significant implications for plant safety in that they will affect the ways in which the operator interacts with and supervises an increasingly complex system. The U.S. Nuclear Regulatory Commission (NRC) reviews the HSI aspects of nuclear plants to ensure that operator performance and reliability are supported. The NRC is developing guidance to support its review of these advanced designs. The guidance consists of an evaluation methodology and an extensive set of human factors guidelines which are used in one aspect of the evaluation. The paper describes the guidance development of the evaluation methodology and the guidelines.

  4. Uncertainty and Sensitivity Analyses Plan. Draft for Peer Review: Hanford Environmental Dose Reconstruction Project

    SciTech Connect

    Simpson, J.C.; Ramsdell, J.V. Jr.

    1993-04-01

    Hanford Environmental Dose Reconstruction (HEDR) Project staff are developing mathematical models to be used to estimate the radiation dose that individuals may have received as a result of emissions since 1944 from the US Department of Energy`s (DOE) Hanford Site near Richland, Washington. An uncertainty and sensitivity analyses plan is essential to understand and interpret the predictions from these mathematical models. This is especially true in the case of the HEDR models where the values of many parameters are unknown. This plan gives a thorough documentation of the uncertainty and hierarchical sensitivity analysis methods recommended for use on all HEDR mathematical models. The documentation includes both technical definitions and examples. In addition, an extensive demonstration of the uncertainty and sensitivity analysis process is provided using actual results from the Hanford Environmental Dose Reconstruction Integrated Codes (HEDRIC). This demonstration shows how the approaches used in the recommended plan can be adapted for all dose predictions in the HEDR Project.

  5. Request For Guidance in Drafting a SIP Deficiency Notice For Michigan's Nonattainment New Source Review Program

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  6. 34 CFR 462.10 - How does the Secretary review tests?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the Secretary review tests? 462.10 Section 462.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... SYSTEM FOR ADULT EDUCATION What Process Does the Secretary Use To Review the Suitability of Tests for...

  7. Air quality criteria for ozone and other photochemical oxidants. External Review Draft No. 2. Volume 5

    SciTech Connect

    Horstman, D.H.; Horvath, S.M.; Raub, J.A.

    1985-11-01

    Scientific information is presented and evaluated relative to the health and welfare effects associated with exposure to ozone and other photochemical oxidants. Although not intended as a complete and detailed literature review, the document covers pertinent literature through early 1985. Data on health and welfare effects are emphasized, but additional information is provided for understanding the nature of the oxidant pollution problem and for evaluating the reliability of effects data as well as their relevance to potential exposures to ozone and other oxidants at concentrations occurring in ambient air. Information is presented on the following exposure-related topics: nature, source, measurement, and concentrations of precursors to ozone and other photochemical oxidants; formation of ozone and other photochemical oxidants and their transport once formed; properties, chemistry, and measurement of ozone and other photochemical oxidants; and concentrations of ozone and other photochemical oxidants typically found in ambient air. Chapters on health and welfare effects address the toxicological effects of ozone and other oxidants; effects observed in controlled human exposures; effects observed in field and epidemiological studies; effects on vegetation seen in field and controlled exposures; effects on natural and agroecosystems; and effects on nonbiological materials observed in field and chamber studies.

  8. 76 FR 72006 - Draft Interim Staff Guidance: Evaluations of Uranium Recovery Facility Surveys of Radon and Radon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-21

    ... COMMISSION Draft Interim Staff Guidance: Evaluations of Uranium Recovery Facility Surveys of Radon and Radon... Recovery Facility Surveys of Radon and Radon Progeny in Air and Demonstrations of Compliance with 10 CFR 20... that existing guidance does not sufficiently detail how the NRC staff reviews surveys of radon...

  9. DOE Hydrogen Program: 2005 Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    Chalk, S. G.

    2005-09-01

    This report summarizes comments from the Peer Review Panel at the FY 2005 DOE Hydrogen Program Annual Merit Review, held on May 23-26, 2005, in Arlington, Virginia. The projects evaluated support the Department of Energy and President Bush's Hydrogen Initiative. The results of this merit review and peer evaluation are major inputs used by DOE to make funding decisions. Project areas include hydrogen production and delivery; hydrogen storage; fuel cells; technology validation; safety, codes and standards; education; and systems analysis.

  10. DOE Hydrogen Program: 2006 Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    Milliken, J.

    2006-09-01

    This report summarizes comments from the Peer Review Panel at the FY 2006 DOE Hydrogen Program Annual Merit Review, held on May 16-19, 2006, in Arlington, Virginia. The projects evaluated support the Department of Energy and President Bush's Hydrogen Initiative. The results of this merit review and peer evaluation are major inputs used by DOE to make funding decisions. Project areas include hydrogen production and delivery; hydrogen storage; fuel cells; technology validation; safety, codes and standards; education; and systems analysis.

  11. Complex-wide review of DOE`s management of low-level radioactive waste - progress to date

    SciTech Connect

    Letourneau, M.J.

    1995-12-31

    The Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-2 includes a recommendation that the Department of Energy (DOE) conduct a comprehensive, complex-wide review of the low-level waste issue to establish the dimensions of the low-level waste problem and to identify necessary corrective actions to address the safe disposition of past, present, and future volumes. DOE`s Implementation Plan calls for the conduct of a complex-wide review of low-level radioactive waste treatment, storage, and disposal sites to identify environmental, safety, and health vulnerabilities. The complex-wide review focuses on low-level waste disposal facilities through a site evaluation survey, reviews of existing documentation, and onsite observations. Low-level waste treatment and storage facilities will be assessed for their ability to meet waste acceptance criteria for disposal. Results from the complex-wide review will be used to form the basis for an integrated and planned set of actions to correct the identified vulnerabilities and to prompt development of new requirements for managing low-level waste.

  12. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (Rdx) (Public Comment Draft)

    EPA Science Inventory

    EPA is developing an Integrated Risk Information System (IRIS) assessment of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and has released the draft assessment for public comment. When final, the assessment will appear on the IRIS database.

  13. An Assessment of Potential Mining Impacts on Salmon Ecosystems of Bristol Bay, Alaska (Second External Review Draft)

    EPA Science Inventory

    Cover of the Second <span class=Draft of the Bristol Bay Assessment Report"> [UPDATE] In March 2014, EPA released a response to public commen...

  14. 77 FR 45357 - Draft Guidance for Industry and Food and Drug Administration Staff; Acceptance and Filing Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... and Research. This draft guidance is not final nor is it in effect at this time. DATES: Although you... Development (HFM-40), Center for Biologics Evaluation and Research, Food and Drug Administration, 1401..., Center for Biologics Evaluation and Research (HFM-17), Food and Drug Administration, 1401 Rockville...

  15. Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for Risk Assessment (External Review Draft)

    EPA Science Inventory

    This draft report provides an overview of the types of mechanisms underlying the lymphohematopoietic cancers induced by chemical agents and radiation in humans, with a primary emphasis on leukemia and leukemia-inducing agents. It focuses on how mechanistic information on human l...

  16. 75 FR 7477 - Draft Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of... Integrated Risk Information System (IRIS)'' (EPA/635/R-10/001). The draft document was prepared by the... Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System...

  17. An Assessment of Potential Mining Impacts on Salmon Ecosystems of Bristol Bay, Alaska (First External Review Draft)

    EPA Science Inventory

    Cover of the Bristol Bay, Alaska <span class=Draft Assessment Report"> [UPDATE] In March 2014, EPA released a response to public comment...

  18. Implications of Climate Change for State Bioassessment Programs and Approaches to Account for Effects (External Review Draft)

    EPA Science Inventory

    This draft report uses biological data collected by four states in wadeable rivers and streams to examine the components of state and tribal bioassessment and biomonitoring programs that may be vulnerable to climate change. The study investigates the potential to identify biologi...

  19. Integrated Science Assessment (ISA) for Oxides of Nitrogen, Oxides of Sulfur and Particulate Matter Ecological Criteria (First External Review Draft)

    EPA Science Inventory

    This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision on retaining or revising the current secondary standards for NO2, SO2, PM 2.5 and PM 10 since the prior re...

  20. Does Individual Development Account Participation Help the Poor? A Review

    ERIC Educational Resources Information Center

    Richards, Kristin V.; Thyer, Bruce A.

    2011-01-01

    Objectives: The purpose of this study is to review the current empirical research regarding the financial effects of participation in Individual Development Account (IDA) programs. Methods: Peer-reviewed outcome studies identified through electronic bibliographic databases and manual searches of article reference lists are reviewed. A total of 1…

  1. 42 CFR 137.134 - When does the 45 day review period begin?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false When does the 45 day review period begin? 137.134 Section 137.134 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH... the 45 day review period begin? The 45 day review period begins from the date the IHS receives...

  2. 42 CFR 137.134 - When does the 45 day review period begin?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false When does the 45 day review period begin? 137.134 Section 137.134 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH... the 45 day review period begin? The 45 day review period begins from the date the IHS receives...

  3. 42 CFR 137.134 - When does the 45 day review period begin?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false When does the 45 day review period begin? 137.134 Section 137.134 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH... the 45 day review period begin? The 45 day review period begins from the date the IHS receives...

  4. Review of DOE Waste Package Program. Semiannual report, October 1984-March 1985. Volume 8

    SciTech Connect

    Davis, M.S.

    1985-12-01

    A large number of technical reports on waste package component performance were reviewed over the last year in support of the NRC`s review of the Department of Energy`s (DOE`s) Environmental Assessment reports. The intent was to assess in some detail the quantity and quality of the DOE data and their relevance to the high-level waste repository site selection process. A representative selection of the reviews is presented for the salt, basalt, and tuff repository projects. Areas for future research have been outlined. 141 refs.

  5. Status of GEA review of DOE geothermal research program

    SciTech Connect

    Wright, P.M.

    1996-12-31

    The Geothermal Energy Association (GEA) will be conducting a series of workshops related to the DOE Research and Development (R&D) program, the first of which will take place tomorrow and the next day. This workshop will be focussing on drilling research and development. The objective of these workshops is to provide information and recommendations to DOE on the R&D needs and priorities of the geothermal industry. As a GEA officer, I will be conducting these workshops and it is something you might guess I am interested in. I have been interested in geothermal R&D for 20 years now.

  6. 10 CFR 712.16 - DOE security review.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... personnel security file review of an HRP candidate and HRP-certified individual upon receiving the... security file review is favorable, this information must be forwarded to the HRP certifying official. If... of the HRP process, the HRP certifying official must be notified and the security concern...

  7. 10 CFR 712.16 - DOE security review.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... personnel security file review of an HRP candidate and HRP-certified individual upon receiving the... security file review is favorable, this information must be forwarded to the HRP certifying official. If... of the HRP process, the HRP certifying official must be notified and the security concern...

  8. 10 CFR 712.16 - DOE security review.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... personnel security file review of an HRP candidate and HRP-certified individual upon receiving the... security file review is favorable, this information must be forwarded to the HRP certifying official. If... of the HRP process, the HRP certifying official must be notified and the security concern...

  9. 10 CFR 712.16 - DOE security review.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... personnel security file review of an HRP candidate and HRP-certified individual upon receiving the... security file review is favorable, this information must be forwarded to the HRP certifying official. If... of the HRP process, the HRP certifying official must be notified and the security concern...

  10. 10 CFR 712.16 - DOE security review.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... personnel security file review of an HRP candidate and HRP-certified individual upon receiving the... security file review is favorable, this information must be forwarded to the HRP certifying official. If... of the HRP process, the HRP certifying official must be notified and the security concern...

  11. A review of DOE HEPA filter component test activities

    SciTech Connect

    Slawski, J.W.; Bresson, J.F.; Scripsick, R.C.

    1997-08-01

    All HEPA filters purchased for installation in DOE nuclear facilities are required to be tested at a Filter Test Facility (FTF) prior to installation. The number of HEPA filters purchased by DOE has been reduced so much that the Hanford FTF was closed. From Fiscal Year (FY) 1992 to 1994, funding was not provided to the FTF Technical Support Group (TSG) at the Los Alamos National Laboratory. As a consequence, Round Robin Tests (RRTs), performed twice each year by the FTFs to assess constituency of test results among the FTFs, were not performed in FY 1992 and FY 1993. The Annual Reports of FTF test activities were not prepared for FY 1992 - 1995. Technical support provided to the FTFs was minimal. There is talk of closing a second FTF, and ongoing discussions as to whether DOE will continue to fund operation of the FTFs. In FY 1994, DOE Defense Programs commenced funding the TSG. RRT data for FY 1994 and 1995 have been entered into the database; the FY 1994 RRT report has been issued; and the FY 1995 RRT report is in progress. Data from semiannual reports have been retrieved and entered into the database. Standards related to HEPA filter test and procurement activities are now scheduled for issuance by FY 1996. Continuation of these activities depends on whether DOE will continue to support the HEPA filter test program. The history and activities of the FTFs and the TSG at Los Alamos have been reported at previous Air Cleaning Conferences. Data from the FY 1991 Annual Report of FTF activities was presented at the 1992 Air Cleaning Conference. Preparation of the Annual Reports was temporarily suspended in 1992. However, all of the FTF Semiannual report data have been retrieved and entered into the data base. This paper focuses primarily on the results of HEPA filter tests conducted by FTFs during FY 1992 - FY 1995, and the possible effects of the DOE program uncertainties on the quality of HEPA filters for installation at the DOE sites. 15 refs., 13 tabs.

  12. Review of Natural Phenomena Hazard (NPH) Assessments for the DOE Hanford Site

    SciTech Connect

    Snow, Robert L.; Ross, Steven B.

    2011-09-15

    The purpose of this review is to assess the need for updating Natural Phenomena Hazard (NPH) assessments for the DOE's Hanford Site, as required by DOE Order 420.1B Chapter IV, Natural Phenomena Hazards Mitigation, based on significant changes in state-of-the-art NPH assessment methodology or site-specific information. This review is an update and expansion to the September 2010 review of PNNL-19751, Review of Natural Phenomena Hazard (NPH) Assessments for the Hanford 200 Areas (Non-Seismic).

  13. Proceedings of the 1995 U.S. DOE hydrogen program review, Volume 1

    SciTech Connect

    1995-09-01

    This document containes reports from the proceedings of the 1995 U.S. DOE hydrogen program review. Reports are organized under the topics of systems analysis, utilization, storage, and production. This volume, Volume I, contains the reports concerned with systems analysis and utilization. Individual reports were processed separately for the DOE data bases.

  14. 77 FR 8890 - Clarks River National Wildlife Refuge, KY; Draft Comprehensive Conservation Plan and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... availability of a draft comprehensive conservation plan and environmental assessment (Draft CCP/EA) for Clarks... review and comment. In this Draft CCP/EA, we describe the alternative we propose to use to manage this... receive your written comments by March 16, 2012. ADDRESSES: You may obtain a copy of the Draft CCP/EA...

  15. 76 FR 72919 - Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... AGENCY Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants AGENCY..., ``Second External Review Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants... review of the national ambient air quality standards (NAAQS) for ozone. DATES: The public comment...

  16. 76 FR 17121 - Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-28

    ... AGENCY Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants AGENCY..., ``First External Review Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants... review of the national ambient air quality standards (NAAQS) for ozone. DATES: The public comment...

  17. How does obesity affect the endocrine system? A narrative review.

    PubMed

    Poddar, M; Chetty, Y; Chetty, V T

    2017-03-15

    Obesity is a chronic, relapsing medical condition that results from an imbalance of energy expenditure and consumption. It is a leading cause of preventable illness, disability and premature death. The causes of obesity are multifactorial and include behavioural, socioeconomic, genetic, environmental and psychosocial factors. Rarely are endocrine diseases, e.g., hypothyroidism or Cushing's syndrome, the cause of obesity. What is less understood is how obesity affects the endocrine system. In this review, we will discuss the impact of obesity on multiple endocrine systems, including the hypothalamic-pituitary axis, changes in vitamin D homeostasis, gender steroids and thyroid hormones. We will also examine the renin angiotensin aldosterone system and insulin pathophysiology associated with obesity. We will provide a general overview of the biochemical changes that can be seen in patients with obesity, review possible aetiologies of these changes and briefly consider current guidelines on their management. This review will not discuss endocrine causes of obesity.

  18. Assessment of documentation requirements under DOE 5481. 1, Safety Analysis and Review System (SARS)

    SciTech Connect

    Browne, E.T.

    1981-03-01

    This report assesses the requirements of DOE Order 5481.1, Safety Analysis and Review System for DOE Operations (SARS) in regard to maintaining SARS documentation. Under SARS, all pertinent details of the entire safety analysis and review process for each DOE operation are to be traceable from the initial identification of a hazard. This report is intended to provide assistance in identifying the points in the SARS cycle at which documentation is required, what type of documentation is most appropriate, and where it ultimately should be maintained.

  19. Does Incubation Enhance Problem Solving? A Meta-Analytic Review

    ERIC Educational Resources Information Center

    Sio, Ut Na; Ormerod, Thomas C.

    2009-01-01

    A meta-analytic review of empirical studies that have investigated incubation effects on problem solving is reported. Although some researchers have reported increased solution rates after an incubation period (i.e., a period of time in which a problem is set aside prior to further attempts to solve), others have failed to find effects. The…

  20. Does Being Overweight Impede Academic Attainment? A Systematic Review

    ERIC Educational Resources Information Center

    Caird, Jennifer; Kavanagh, Josephine; O'Mara-Eves, Alison; Oliver, Kathryn; Oliver, Sandy; Stansfield, Claire; Thomas, James

    2014-01-01

    Objectives: To examine evidence from studies exploring the relationship between childhood obesity and educational attainment. Design: A systematic review of secondary analyses and observational studies published in English after 1997 examining attainment as measured by grade point average or other validated measure, in children aged 6 to 16 years,…

  1. Social capital and health: Does egalitarianism matter? A literature review

    PubMed Central

    Islam, M Kamrul; Merlo, Juan; Kawachi, Ichiro; Lindström, Martin; Gerdtham, Ulf-G

    2006-01-01

    The aim of the paper is to critically review the notion of social capital and review empirical literature on the association between social capital and health across countries. The methodology used for the review includes a systematic search on electronic databases for peer-reviewed published literature. We categorize studies according to level of analysis (single and multilevel) and examine whether studies reveal a significant health impact of individual and area level social capital. We compare the study conclusions according to the country's degrees of economic egalitarianism. Regardless of study design, our findings indicate that a positive association (fixed effect) exists between social capital and better health irrespective of countries degree of egalitarianism. However, we find that the between-area variance (random effect) in health tends to be lower in more egalitarian countries than in less egalitarian countries. Our tentative conclusion is that an association between social capital and health at the individual level is robust with respect to the degree of egalitarianism within a country. Area level or contextual social capital may be less salient in egalitarian countries in explaining health differences across places. PMID:16597324

  2. 2010 DOE Hydrogen Program Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    none,

    2010-12-01

    This report summarizes comments from the Peer Review Panel at the 2010 DOE Hydrogen Program Annual Merit Review, held on June 7-11, 2010, in Washington, DC. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; education; and systems analysis.

  3. 2011 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    none,

    2011-09-01

    This report summarizes comments from the Peer Review Panel at the 2011 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on May 9-13, 2011, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; education; market transformation; and systems analysis.

  4. DOE Hydrogen Program: 2010 Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    Not Available

    2010-12-01

    This document summarizes the comments provided by peer reviewers on hydrogen and fuel cell projects presented at the FY 2010 U.S. Department of Energy (DOE) Hydrogen Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting (AMR), held June 7-11, 2010 in Washington, D.C.

  5. 2013 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    none,

    2013-10-01

    This report summarizes comments from the Peer Review Panel at the 2013 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on May 13-17, 2013, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; market transformation; and systems analysis.

  6. 2012 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    none,

    2012-09-01

    This report summarizes comments from the Peer Review Panel at the 2012 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on May 14-18, 2012, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; education; market transformation; and systems analysis.

  7. 2008 DOE Hydrogen Program Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    none,

    2008-06-13

    This report summarizes comments from the Peer Review Panel at the 2008 DOE Hydrogen Program Annual Merit Review, held on June 9-13, 2008, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; technology validation; safety, codes, and standards; education; systems analysis; and manufacturing.

  8. 2014 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    none,

    2014-10-01

    This report summarizes comments from the Peer Review Panel at the 2014 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on June 16-20, 2014, in Washington, DC. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; market transformation; and systems analysis.

  9. 34 CFR 86.101 - What review of IHE drug prevention programs does the Secretary conduct?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false What review of IHE drug prevention programs does the Secretary conduct? 86.101 Section 86.101 Education Office of the Secretary, Department of Education DRUG AND ALCOHOL ABUSE PREVENTION Institutions of Higher Education § 86.101 What review of IHE drug...

  10. 34 CFR 86.101 - What review of IHE drug prevention programs does the Secretary conduct?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false What review of IHE drug prevention programs does the Secretary conduct? 86.101 Section 86.101 Education Office of the Secretary, Department of Education DRUG AND ALCOHOL ABUSE PREVENTION Institutions of Higher Education § 86.101 What review of IHE drug...

  11. 34 CFR 86.101 - What review of IHE drug prevention programs does the Secretary conduct?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false What review of IHE drug prevention programs does the Secretary conduct? 86.101 Section 86.101 Education Office of the Secretary, Department of Education DRUG AND ALCOHOL ABUSE PREVENTION Institutions of Higher Education § 86.101 What review of IHE drug...

  12. 34 CFR 86.101 - What review of IHE drug prevention programs does the Secretary conduct?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What review of IHE drug prevention programs does the Secretary conduct? 86.101 Section 86.101 Education Office of the Secretary, Department of Education DRUG AND ALCOHOL ABUSE PREVENTION Institutions of Higher Education § 86.101 What review of IHE drug...

  13. 34 CFR 86.101 - What review of IHE drug prevention programs does the Secretary conduct?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false What review of IHE drug prevention programs does the Secretary conduct? 86.101 Section 86.101 Education Office of the Secretary, Department of Education DRUG AND ALCOHOL ABUSE PREVENTION Institutions of Higher Education § 86.101 What review of IHE drug...

  14. 2009 DOE Hydrogen Program Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    Satyapal, S.

    2009-10-01

    This report summarizes comments from the Peer Review Panel at the 2009 DOE Hydrogen Program Annual Merit Review, held on May 18-22, 2009, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; education; safety, codes, and standards; technology validation; systems analysis; and manufacturing R&D.

  15. 2015 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    none,

    2015-10-01

    This report summarizes comments from the Peer Review Panel at the 2015 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on June 8-12, 2015, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; market transformation; and systems analysis.

  16. 1990 DOE/SANDIA crystalline photovoltaic technology project review meeting

    SciTech Connect

    Ruby, D.S.

    1990-07-01

    This document serves as the proceedings for the annual project review meeting held by Sandia's Photovoltaic Cell Research Division and Photovoltaic Technology Division. It contains information supplied by each organization making a presentation at the meeting, which was held August 7 through 9, 1990 at the Sheraton Hotel in Albuquerque, New Mexico. Sessions were held to discuss national photovoltaic programs, one-sun crystalline silicon cell research, concentrator silicon cell research, concentrator 3-5 cell research, and concentrating collector development.

  17. DOE Hydrogen Program: 2007 Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    Milliken, J.

    2007-09-01

    This report summarizes comments from the Peer Review Panel at the FY 2007 DOE Hydrogen Program Annual Merit Review, held on May 14-18, 2007, in Washington, D.C. The projects evaluated support the Department of Energy and President Bush's Hydrogen Initiative. The results of this merit review and peer evaluation are major inputs used by DOE to make funding decisions. Project areas include hydrogen production and delivery; hydrogen storage; fuel cells; technology validation; safety, codes and standards; education; and systems analysis.

  18. 76 FR 10893 - Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... AGENCY Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants AGENCY... review draft of a document titled, ``First External Review Draft Integrated Science Assessment for Ozone... review of the national ambient air quality standards (NAAQS) for ozone. EPA is releasing this...

  19. Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (2011 Interagency Science Discussion Draft)

    EPA Science Inventory

    On September 22, 2006, the draft Evaluation of the Carinogenicity of Ethylene Oxide (EPA/635/R-06/003) and the draft charge to external peer reviewers were released for external peer review and public comment. This draft was reviewed by EPA’s Science Advisory Board (SAB)...

  20. Peer-review study of the draft handbook for human-reliability analysis with emphasis on nuclear-power-plant applications, NUREG/CR-1278

    SciTech Connect

    Brune, R. L.; Weinstein, M.; Fitzwater, M. E.

    1983-01-01

    This report describes a peer review of the draft Handbook for Human Reliability Analysis with Emphasis on Nuclear Power Plant Applications, NUREG/CR-1278. The purpose of the study was to determine to what extent peers agree with the human behavior models and estimates of human error probabilities (HEPs) contained in the Handbook. Twenty-nine human factors experts participated in the study. Twenty of the participants were Americans; nine were from other countries. The peers performed human reliability analyses of a variety of human performance scenarios describing operator activities in nuclear power plant settings. They also answered questionnaires pertaining to the contents and application of the Handbook. An analysis of peer solutions to the human reliability analysis problems and peer responses to the questionnaire was performed. Recommendations regarding the format and contents of the Handbook were developed from the study findings.

  1. Does narrative information bias individual's decision making? A systematic review.

    PubMed

    Winterbottom, Anna; Bekker, Hilary L; Conner, Mark; Mooney, Andrew

    2008-12-01

    Including narratives in health-care interventions is increasingly popular. However, narrative information may bias individual's decision making, resulting in patients making poorer decisions. This systematic review synthesises the evidence about the persuasiveness of narrative information on individuals' decision making. Seventeen studies met the review criteria; 41% of studies employed first person narration, 59% third person. Narrative information influenced decision making more than the provision of no additional information and/or statistically based information in approximately a third of the studies (5/17); studies employing first person narratives were twice as likely to find an effect. There was some evidence that narrative information encouraged the use of heuristic rather than systematic processing. However, there was little consistency in the methods employed and the narratives' content to provide evidence on why narratives affect the decision process and outcome, whether narratives facilitate or bias decision making, and/or whether narratives affect the quality of the decision being made. Until evidence is provided on why and how narratives influence decision making, the use of narratives in interventions to facilitate medical decision making should be treated cautiously.

  2. Accelerating Cleanup: Focus on 2006. Discussion draft

    SciTech Connect

    1997-06-01

    This executive summary addresses the activities associated with the National Transuranic (TRU) Program managed by the Carlsbad Area Office (CAO). The CAO programmatically reports to the Assistant Secretary for Environmental Management and receives administrative support through the Albuquerque Operations Office. The mission of the Carlsbad Area Office (CAO) is to protect human health and the environment by opening and operating the Waste Isolation Pilot Plant for site disposal of TRU waste and by establishing an effective system for management of TRU waste from generation to disposal. It includes personnel assigned to the CAO, the Waste Isolation Pilot Plant (WIPP) site operations, and other activities associated with the National TRU Program. The CAO develops and directs implementation of the program, while the DOE Headquarters establishes policy and guidelines. The CAO assesses compliance with the program guidance, as well as the commonality of activities and assumptions among all the sites. Since the development of the February 28, 1997, database used to develop this Discussion Draft, the opening of the WIPP facility for receipt of Contact Handled waste has been delayed from November 1997 to May 1998. This slippage is significant enough to require a change in the milestones and volumes included in the documents to be reviewed by our stakeholders. Changes have been incorporated into this Discussion Draft and its supporting Project Baseline Summaries (PBSs).

  3. Why does carbon dioxide resurfacing work? A review.

    PubMed

    Ross, E V; McKinlay, J R; Anderson, R R

    1999-04-01

    Despite the unquestionable efficacy of carbon dioxide laser skin resurfacing, mechanisms for cosmetic enhancement remain poorly characterized. Histological studies have provided some insight into the cascade of events from initial laser impact to final skin rejuvenation. However, there are few comprehensive studies of gross and microscopic wound healing. Additionally, the literature is fragmented; excellent individual articles appear in journals from widely disparate disciplines. For example, some reports relevant to laser skin resurfacing are "sequestered" in the engineering literature. This article is intended to update the physician on laser skin resurfacing based on the broadest review of the current literature. It proceeds from a discussion of initial laser-tissue interactions, such as collagen denaturation, to examination of long-term biological sequelae. At some cost to scientific rigor, mathematical models describing laser-tissue interactions are not presented.

  4. Review article: dexmedetomidine: does it have potential in palliative medicine?

    PubMed

    Prommer, Eric

    2011-06-01

    Dexmedetomidine, is a α( 2) adrenergic agonist approved by the Food and Drug administration for sedation and analgesia. A highly potent α(2) adrenergic agonist, it has quick onset of action, with peak effects within 1 hour of administration. It is metabolized in the liver and eliminated in the urine as a glucuronide. Dexmedetomidine is a substrate and inhibitor of cytochrome oxidase 2D6, but clinical evidence of significant drug interactions is lacking. Clinical trials suggest efficacy for the treatment of delirium in the intensive care unit setting with efficacy comparable to haloperidol and benzodiazepines. Dexmedetomidine also has an opioid-sparing action and can act to enhance analgesia. The purpose of this article is to review the pharmacodynamics and pharmacology of dexmedetomidine, and examine its potential use in the palliative care population, especially with regard to the management of delirium.

  5. Does gamification increase engagement with online programs? A systematic review

    PubMed Central

    Looyestyn, Jemma; Kernot, Jocelyn; Boshoff, Kobie; Ryan, Jillian; Edney, Sarah; Maher, Carol

    2017-01-01

    Background Engagement in online programs is difficult to maintain. Gamification is the recent trend that offers to increase engagement through the inclusion of game-like features like points and badges, in non-game contexts. This review will answer the following question, ‘Are gamification strategies effective in increasing engagement in online programs?’ Method Eight databases (Web of Science, PsycINFO, Medline, INSPEC, ERIC, Cochrane Library, Business Source Complete and ACM Digital Library) were searched from 2010 to the 28th of October 2015 using a comprehensive search strategy. Eligibility criteria was based on the PICOS format, where “population” included adults, “intervention” involved an online program or smart phone application that included at least one gamification feature. “Comparator” was a control group, “outcomes” included engagement and “downstream” outcomes which occurred as a result of engagement; and “study design” included experimental studies from peer-reviewed sources. Effect sizes (Cohens d and 95% confidence intervals) were also calculated. Results 1017 studies were identified from database searches following the removal of duplicates, of which 15 met the inclusion criteria. The studies involved a total of 10,499 participants, and were commonly undertaken in tertiary education contexts. Engagement metrics included time spent (n = 5), volume of contributions (n = 11) and occasions visited to the software (n = 4); as well as downstream behaviours such as performance (n = 4) and healthy behaviours (n = 1). Effect sizes typically ranged from medium to large in direct engagement and downstream behaviours, with 12 out of 15 studies finding positive significant effects in favour of gamification. Conclusion Gamification is effective in increasing engagement in online programs. Key recommendations for future research into gamification are provided. In particular, rigorous study designs are required to fully examine

  6. DOE High Performance Computing Operational Review (HPCOR): Enabling Data-Driven Scientific Discovery at HPC Facilities

    SciTech Connect

    Gerber, Richard; Allcock, William; Beggio, Chris; Campbell, Stuart; Cherry, Andrew; Cholia, Shreyas; Dart, Eli; England, Clay; Fahey, Tim; Foertter, Fernanda; Goldstone, Robin; Hick, Jason; Karelitz, David; Kelly, Kaki; Monroe, Laura; Prabhat,; Skinner, David; White, Julia

    2014-10-17

    U.S. Department of Energy (DOE) High Performance Computing (HPC) facilities are on the verge of a paradigm shift in the way they deliver systems and services to science and engineering teams. Research projects are producing a wide variety of data at unprecedented scale and level of complexity, with community-specific services that are part of the data collection and analysis workflow. On June 18-19, 2014 representatives from six DOE HPC centers met in Oakland, CA at the DOE High Performance Operational Review (HPCOR) to discuss how they can best provide facilities and services to enable large-scale data-driven scientific discovery at the DOE national laboratories. The report contains findings from that review.

  7. Does incubation enhance problem solving? A meta-analytic review.

    PubMed

    Sio, Ut Na; Ormerod, Thomas C

    2009-01-01

    A meta-analytic review of empirical studies that have investigated incubation effects on problem solving is reported. Although some researchers have reported increased solution rates after an incubation period (i.e., a period of time in which a problem is set aside prior to further attempts to solve), others have failed to find effects. The analysis examined the contributions of moderators such as problem type, presence of solution-relevant or misleading cues, and lengths of preparation and incubation periods to incubation effect sizes. The authors identified a positive incubation effect, with divergent thinking tasks benefiting more than linguistic and visual insight tasks from incubation. Longer preparation periods gave a greater incubation effect, whereas filling an incubation period with high cognitive demand tasks gave a smaller incubation effect. Surprisingly, low cognitive demand tasks yielded a stronger incubation effect than did rest during an incubation period when solving linguistic insight problems. The existence of multiple types of incubation effect provides evidence for differential invocation of knowledge-based vs. strategic solution processes across different classes of problem, and it suggests that the conditions under which incubation can be used as a practical technique for enhancing problem solving must be designed with care.

  8. Does yoga engender fitness in older adults? A critical review.

    PubMed

    Roland, Kaitlyn P; Jakobi, Jennifer M; Jones, Gareth R

    2011-01-01

    Interest in yoga is growing, especially among older adults. This review critically summarizes the current literature to investigate whether physical fitness and function benefits are engendered through the practice of yoga in older adults. A comprehensive search yielded 507 studies; 10 studies with 544 participants (69.6 ± 6.3 yr, 71% female) were included. Large variability in yoga styles and measurement outcomes make it challenging to interpret results across studies. Studies reported moderate improvements for gait (ES = 0.54, 0.80), balance (ES = 0.25-1.61), upper/lower body flexibility (ES = 0.25, 0.70), lower body strength (ES = 0.51), and weight loss (ES = 0.73, 0.99).Yoga may engender improvements in some components of fitness in older adults. However, more evidence is needed to determine its effectiveness as an alternative exercise to promote fitness in older adults. Further investigation into yoga as an exercise activity for older adults is warranted.

  9. Does exercise reduce brain oxidative stress? A systematic review.

    PubMed

    Camiletti-Moirón, D; Aparicio, V A; Aranda, P; Radak, Z

    2013-08-01

    The aim of the present systematic review was to investigate the influence of different exercise programs on brain oxidative stress. A search of the literature was conducted up to 1 December 2012 across five databases: PUBMED, SCOPUS, SPORTS DISCUS, Web of Science, and The Cochrane Library. The search strategy used in the electronic databases mentioned was established as: (swim* OR exercise OR training) AND ("oxidative stress" AND brain) for each database. A methodological quality assessment valuation/estimation was additionally carried out in the final sample of studies. Of 1553 potentially eligible papers, 19 were included after inclusion and exclusion criteria. The methodological quality assessment showed a total score in the Quality Index between 40% and 80%, with a mean quality of 56.8%. Overall, regular moderate aerobic exercise appears to promote antioxidant capacity on brain. In contrast, anaerobic or high-intensity exercise, aerobic-exhausted exercise, or the combination of both types of training could deteriorate the antioxidant response. Future investigations should be focused on establishing a standardized exercise protocol, depending on the exercise metabolism wanted to test, which could enhance the objective knowledge in this topic.

  10. Cause of Death in “John Doe & Jane Doe”: A 5 year review

    PubMed Central

    Dasari, Harish; Singh, Amandeep

    2014-01-01

    Sometimes the opinion regarding the cause of death in “John Doe or Jane Doe” i.e. on unknown dead bodies is a test of ability of the forensic expert and on many occasions it yields little or no results. Here the identification of the body as such poses problems; rest aside the opinion regarding the cause/ manner of death. The present 5yr study was undertaken in the Department of Forensic Medicine & Toxicology, Government Medical College & Hospital, Chandigarh to find the patterns of cause of death in unknown dead bodies, as very little literature is available with regard to John Doe or Jane Doe cases as a group, in India. Unidentified bodies comprised 4 % of the total 3165 cases brought for post-mortem examination to the department. Maximum cases belonged to the age group 41 - 50 years, 30 %. Majority of the opinions regarding the cause of death were given as “no definite opinion” (31%), followed by “cranio-cerebral damage” (30 %) and coronary insufficiency/ Cardiac disease/ aortic aneurysm rupture, (8.9%). Following measures should be undertaken to increase the chances of getting these unknown bodies identified and thereby increasing the chances of arriving at a definite cause of death: drafting of additional legislation for the management of unidentified dead bodies along with streamlining of work on the part of police, use of active investigation and modern investigative techniques, fixing the accountability of the police. Internet based sites of the police like ZIPNET (Zonal Integrated Police Networking) in Northern India, should also be used. PMID:25302219

  11. Does ultrasongraphy predict intraoperative findings at cholecystectomy? An institutional review

    PubMed Central

    Stogryn, Shannon; Metcalfe, Jennifer; Vergis, Ashley; Hardy, Krista

    2016-01-01

    Background Ultrasonography (US) is the mainstay of biliary tract imaging, but few recent studies have tested its ability to diagnose acute cholecystitis (AC). Our objective was to determine how well a US diagnosis of AC correlates with the intraoperative diagnosis. We hypothesize that US underestimates this diagnosis, potentially leading to unexpected findings in the operating room (OR). Methods This retrospective review included all patients admitted to the acute care surgical service of a tertiary hospital in 2011 with suspected biliary pathology who underwent US and subsequent cholecystectomy. We determined the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of US using the intraoperative diagnosis as the gold standard. Further analysis identified which US findings were most predictive of an intraoperative diagnosis of AC. We used a recursive partitioning method with random forests to identify unique combinations of US findings that, together, are most predictive of AC. Results In total, 254 patients underwent US for biliary symptoms; 152 had AC diagnosed, and 143 (94%) of them underwent emergency surgery (median time to OR 23.03 hr). Ultrasonography predicted intraoperative findings with a sensitivity of 73.2%, specificity of 85.5% and PPV of 93.7%. The NPV (52.0%) was quite low. The US indicators most predictive of AC were a thick wall, a positive sonographic Murphy sign and cholelithiasis. Recursive partitioning demonstrated that a positive sonographic Murphy sign is highly predictive of intraoperative AC. Conclusion Ultrasonography is highly sensitive and specific for diagnosing AC. The poor NPV confirms our hypothesis that US can underestimate AC. PMID:26574703

  12. Mercury study report to Congress. Volume 4. Health effects of mercury and mercury compounds. Sab review draft

    SciTech Connect

    Schoeny, R.

    1996-06-01

    This volume of the draft Mercury Study Report to Congress summarizes the available information on human health effects and animal data for hazard identification and dose-response assessment for three forms of mercury: elemental mercury, mercury chloride (inorganic mercury), and methylmercury (organic mercury). Effects are summarized by endpoint. The risk assessment evaluates carcinogenicity, mutagenicity, developmental toxicity and general systemic toxicity of these chemical species of mercury. Toxicokinetics (absorption, distribution, metabolism and excretion) are described for each of the three mercury species. PBPK models are described, but not applied in risk assessment. Reference doses are calculated for inorganic and methylmercury; a reference concentration for inhaled elemental mercury is provided. A quantitiative analysis of factors contributing to variability and uncertainty in the methylmercury RfD is provided in an appendix. Interations and sensitive populations are described.

  13. Comprehensive Summary and Analysis of Oral and Written Scoping Comments on the Hawaii Geothermal Project EIS (DOE Review Draft)

    SciTech Connect

    1992-09-18

    This report contains summaries of the oral and written comments received during the scoping process for the Hawaii Geothermal Project (HGP) Environmental Impact Statement (EIS). Oral comments were presented during public scoping meetings; written comments were solicited at the public scoping meetings and in the ''Advance Notice of Intent'' and ''Notice of Intent'' (published in the ''Federal Register'') to prepare the HGP EIS. This comprehensive summary of scoping inputs provides an overview of the issues that have been suggested for inclusion in the HGP EIS.

  14. Geothermal Program Review VII: proceedings. DOE Research and Development for the Geothermal Marketplace

    SciTech Connect

    Not Available

    1989-01-01

    Each year the Geothermal Technology Division of the US Department of Energy conducts an indepth review of its entire geothermal R and D program. The 2--3 day conference serves several purposes: a status report on current R and D activities, an assessment of progress and problems, a review of management issues, and a technology transfer opportunity between DOE and the US geothermal industry. This year's conference, Program Review 7, was held in San Francisco on March 21--23, 1989. As indicated by its title, ''DOE Research and Development for the Geothermal Marketplace'', Program Review 7 emphasized developing technologies, concepts, and innovations having potential for commercial application in the foreseeable future. Program Review 7 was comprised of eight sessions including an opening session and a special presentation on the ''Role of Geothermal Energy in Minimizing Global Environmental Problems.'' The five technical sessions covered GTD-sponsored R and D in the areas of hydrothermal (two sessions), hot dry rock, geopressured, and magma. Presentations were made by the relevant field researchers, and sessions were chaired by the appropriate DOE Operations Office Geothermal Program Manager. The technical papers and commentary of invited speakers contained in these Proceedings have been compiled in the order in which they were presented at Program Review 7.

  15. Proceedings of the 5. DOE review of laboratory programs for women

    SciTech Connect

    1996-12-31

    The Fifth DOE Review of Laboratory Programs for Women was held at Brookhaven National Laboratory, May 6--8, 1996, and was co-sponsored by Princeton Plasma Physics Laboratory. The 1996 Review was organized as a Professional Workshop, that is, there were Invited Talks, plus Oral and Poster Presentations from the participants. These sessions were organized around the Focus Topics selected for the Review. The Focus Topics were: school-lab programs, college programs, positive image of women, cultural audits, employee development, employee mentoring, networking, dependent care, and alternate work schedules. On Monday evening, Toni Joseph gave an informal talk to the participants. She stressed the importance of submitting the Action Items for the respective facilities, and assured them that they would be looked at by the Office of Energy Research. On Tuesday morning, the DOE Points-of-Contact (POC) presented an overview of the past Reviews to give some background on the present DOE Review, and discussed plans for the future. The Review concluded with Focus Sessions, one for each Focus Topic. Each of these sessions was charged with producing a report on the session topic. The Focus Group Reports are included in the Proceedings, along with abstracts to the invited talks, oral presentations and poster presentations.

  16. 76 FR 60820 - Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... AGENCY Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants AGENCY... titled, ``Second External Review Draft Integrated Science Assessment for Ozone and Related Photochemical... ambient air quality standards (NAAQS) for ozone. EPA is releasing this draft document to seek review...

  17. Proceedings of the 1995 U.S. DOE hydrogen program review. Volume II

    SciTech Connect

    1995-09-01

    The 1995 US DOE Hydrogen Program Review was held April 18-21, 1995 in Coral Gables, FL. Volume II of the Proceedings contains 8 papers presented under the subject of hydrogen storage and 17 papers presented on hydrogen production. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  18. Teaching Religion in Public Schools: Review of Warren A. Nord, "Does God Make a Difference?"

    ERIC Educational Resources Information Center

    Feinberg, Walter

    2013-01-01

    In this review of Warren Nord's "Does God Make a Difference? Taking Religion Seriously in Our Schools and Universities," Walter Feinberg provides a detailed analysis of Nord's argument that the study of religion should be constitutionally mandated as a corrective to the overwhelmingly secular course of study offered in…

  19. Review of DOE Planned Change Request for Shielded Containers for Remote-Handled Transuranic Waste

    EPA Pesticide Factsheets

    This report summarizes SC&A's review of the planned change request (PCR) submitted by DOE to EPA proposing the disposal of some remote-handled (RH) transuranic (TRU) waste in shielded containers on the floor of the disposal rooms at WIPP

  20. DOE Lab-Wide Review of Fermilab May 19-20, 1987

    SciTech Connect

    Green, Dan

    1987-05-01

    This book is submitted as a written adjunct to the Annual DOE Lab-Wide Review of Fermilab, scheduled this year for May 19, 20, 1987. In it are described the functions and activities of the various laboratory areas plus statements of plans and goals for the coming year.

  1. Does Cardiopulmonary Resuscitation Cause Rib Fractures in Children? A Systematic Review

    ERIC Educational Resources Information Center

    Maguire, Sabine; Mann, Mala; John, Nia; Ellaway, Bev; Sibert, Jo R.; Kemp, Alison M.

    2006-01-01

    Background: There is a diagnostic dilemma when a child presents with rib fractures after cardiopulmonary resuscitation (CPR) where child abuse is suspected as the cause of collapse. We have performed a systematic review to establish the evidence base for the following questions: (i) Does cardiopulmonary resuscitation cause rib fractures in…

  2. 78 FR 55694 - Draft Research Report: Investigation of Ground Water Contamination Near Pavillion, Wyoming

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Draft Research Report: Investigation of Ground Water Contamination Near Pavillion, Wyoming AGENCY... review of the draft research report titled, ``Investigation of Ground Water Contamination near...

  3. ICLUS Tools and Datasets (Version 1.2) and User's Manual: Arcgis Tools and Datasets for Modeling US Housing Density (External Review Draft)

    EPA Science Inventory

    This draft Geographic Information System (GIS) tool can be used to generate scenarios of housing-density changes and calculate impervious surface cover for the conterminous United States. A draft User’s Guide accompanies the tool. This product distributes the population project...

  4. General Drafting. Technical Manual.

    ERIC Educational Resources Information Center

    Department of the Army, Washington, DC.

    The manual provides instructional guidance and reference material in the principles and procedures of general drafting and constitutes the primary study text for personnel in drafting as a military occupational specialty. Included is information on drafting equipment and its use; line weights, conventions and formats; lettering; engineering charts…

  5. DOE FreedomCAR and vehicle technologies program advanced power electronic and electrical machines annual review report

    SciTech Connect

    Olszewski, Mitch

    2006-10-11

    This report is a summary of the Review Panel at the FY06 DOE FreedomCAR and Vehicle Technologies (FCVT) Annual Review of Advanced Power Electronics and Electric Machine (APEEM) research activities held on August 15-17, 2006.

  6. Draft audit report, human factors engineering control room design review: Saint Lucie Nuclear Power Plant, Unit No. 2

    SciTech Connect

    Peterson, L.R.; Lappa, D.A.; Moore, J.W.

    1981-09-03

    A human factors engineering preliminary design review of the Saint Lucie Unit 2 control room was performed at the site on August 3 through August 7, 1981. This design review was carried out by a team from the Human Factors Engineering Branch, Division of Human Factors Safety. This report was prepared on the basis of the HFEB's review of the applicant's Preliminary Design Assessment and the human factors engineering design review/audit performed at the site. The review team included human factors consultants from BioTechnology, Inc., Falls Church, Virginia, and from Lawrence Livermore National Laboratory (University of California), Livermore, California.

  7. Modelling polymer draft gears

    NASA Astrophysics Data System (ADS)

    Wu, Qing; Yang, Xiangjian; Cole, Colin; Luo, Shihui

    2016-09-01

    This paper developed a new and simple approach to model polymer draft gears. Two types of polymer draft gears were modelled and compared with experimental data. Impact characteristics, in-train characteristics and frequency responses of these polymer draft gears were studied and compared with those of a friction draft gear. The impact simulations show that polymer draft gears can withstand higher impact speeds than the friction draft gear. Longitudinal train dynamics simulations show that polymer draft gears have significantly longer deflections than friction draft gears in normal train operations. The maximum draft gear working velocities are lower than 0.2 m/s, which are significantly lower than the impact velocities during shunting operations. Draft gears' in-train characteristics are similar to their static characteristics but are very different from their impact characteristics; this conclusion has also been reached from frequency response simulations. An analysis of gangway bridge plate failures was also conducted and it was found that they were caused by coupler angling behaviour and long draft gear deflections.

  8. Does thimerosal or other mercury exposure increase the risk for autism? A review of current literature.

    PubMed

    Schultz, Stephen T

    2010-01-01

    This report reviews current literature regarding the association of the pharmaceutical preservative thimerosal and other mercury exposures with the risk for autism. The evidence presented here does not support a causal association between autism and mercury exposure from the preservative thimerosal. The risk for autism from other mercury exposures such as from dental amalgam restorations or environmental mercury release into the atmosphere is ambiguous. Since mercury is a known neurotoxin, more research should be done to ensure that mercury exposure from any source does not contribute to autism.

  9. The mathematical review system: does reviewer status play a role in the citation process?

    PubMed Central

    2010-01-01

    This paper revisits an aspect of citation theory (i.e., citer motivation) with respect to the Mathematical Review system and the reviewer’s role in mathematics. We focus on a set of journal articles (369) published in Singularity Theory (1974–2003), the mathematicians who wrote editorial reviews for these articles, and the number of citations each reviewed article received within a 5 year period. Our research hypothesis is that the cognitive authority of a high status reviewer plays a positive role in how well a new article is received and cited by others. Bibliometric evidence points to the contrary: Singularity Theorists of lower status (junior researchers) have reviewed slightly more well-cited articles (2–5 citations, excluding author self-citations) than their higher status counterparts (senior researchers). One explanation for this result is that lower status researchers may have been asked to review ‘trendy’ or more accessible parts of mathematics, which are easier to use and cite. We offer further explanations and discuss a number of implications for a theory of citation in mathematics. This research opens the door for comparisons to other editorial review systems, such as book reviews written in the social sciences or humanities. PMID:20543874

  10. 25 CFR 30.113 - How does the Secretary review and approve an alternative definition of AYP?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Approval of Alternative Definition § 30.113 How does the Secretary review and approve an alternative definition of AYP? (a) The tribal... 25 Indians 1 2010-04-01 2010-04-01 false How does the Secretary review and approve an...

  11. Draft Scientific Report Connectivity of Streams and Wetlands to Downstream Waters: A Review and Synthesis of the Scientific Evidence

    EPA Pesticide Factsheets

    Synthesizes peer-reviewed scientific literature on the biological, chemical, and hydrologic connectivity of waters and the effects that small streams, wetlands, and open waters have on larger downstream waters such as rivers, lakes, estuaries, and oceans.

  12. 75 FR 71702 - Science Advisory Board Staff Office; Request for Nominations of Experts for Review of EPA's Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... Board (SAB) Staff Office is requesting public nominations for technical experts to augment the SAB's... protection. ] The SAB Staff Office will form an expert panel by augmenting the RAC to review the EPA's...

  13. Draft environmental assessment: Swisher County site, Texas. Nuclear Waste Policy Act (Section 112). [Contains Glossary

    SciTech Connect

    Not Available

    1984-12-01

    In February 1983, the US Department of Energy (DOE) identified a location in Swisher County, Texas, as one of nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. The potentially acceptable site was subsequently narrowed to an area of 9 square miles. To determine their suitability, the Swisher site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for Nuclear Waste Repositories. These evaluations are reported in this draft environmental assessment (EA), which is being issued for public review and comment. The DOE findings and determinations that are based on these evaluations are preliminary and subject to public review and comment. A final EA will be prepared after considering the comments received. On the basis of the evaluations contained in this draft EA, the DOE has found that the Swisher site is not disqualified under the guidelines. The site is contained in the Permian Basin, which is one of five distinct geohydrologic settings considered for the first repository. This setting contains one other potentially acceptable site - the Deaf Smith site. Although the Swisher site appears to be suitable for site characterization, the DOE has concluded that the Deaf Smith site is the preferred site in the Permian Basin and is proposing to nominate the Deaf Smith site rather than the Swisher site as one of the five sites suitable for characterization.

  14. REVIEW OF REMOTE SENSING TECHNOLOGIES AND DATA FOR DOE-EM APPLICATIONS

    SciTech Connect

    M.A. Ebadian, Ph.D

    1999-01-01

    Various governmental agencies and private companies throughout the world are involved in remote sensing activities. Remote sensing is a technology used for the purpose of monitoring the earth's environment, keeping track of the earth's resources, and for agricultural vegetation monitoring, among other things. There is a vast number of remote sensing technologies and data already commercially available for different applications (e.g., environmental, agricultural, and so on). Many entities are actively conducting research to generate new technologies and data (e.g., NASA). In addition, some of DOE's offices and programs have engaged in collection and analysis of remote sensing data. It is likely that some of these technologies and data could be useful for characterization and monitoring of EM's sites. Florida International University's Hemispheric Center for Environmental Technology (FIU-HCET) has reviewed remote sensing technologies and data that are currently available or in an advanced research state. The review focused on the technologies and data applicable to the environmental field. DOE has over 800 national laboratories and sites dispersed throughout the United States. involved in some current and past remote sensing projects. FIU-HCET personnel have searched governmental agency databases (e.g., DOE, NASA), the Internet, and library resources to obtain information about these technologies and generated a user-friendly database. This review km also produced an inventory and will be available on the Internet and on a CD-ROM that can be distributed to individuals or entities requesting information on remote sensing technologies and data for environmental applications. This database contains information regarding each technology, such as type of sensor, applications, and technical specifications (e.g., resolution). To the best of FIU-HCET's knowledge, a database of this type and with this level of detail does not exist within DOE. With the amount of remote

  15. DOE methods for evaluating environmental and waste management samples

    SciTech Connect

    Goheen, S.C.; McCulloch, M.; Thomas, B.L.; Riley, R.G.; Sklarew, D.S.; Mong, G.M.; Fadeff, S.K.

    1994-10-01

    DOE Methods for Evaluating Environmental and Waste Management Samples (DOE Methods) is a resource intended to support sampling and analytical activities for the evaluation of environmental and waste management samples from U.S. Department of Energy (DOE) sites. DOE Methods is the result of extensive cooperation from all DOE analytical laboratories. All of these laboratories have contributed key information and provided technical reviews as well as significant moral support leading to the success of this document. DOE Methods is designed to encompass methods for collecting representative samples and for determining the radioisotope activity and organic and inorganic composition of a sample. These determinations will aid in defining the type and breadth of contamination and thus determine the extent of environmental restoration or waste management actions needed, as defined by the DOE, the U.S. Environmental Protection Agency, or others. The development of DOE Methods is supported by the Analytical Services Division of DOE. Unique methods or methods consolidated from similar procedures in the DOE Procedures Database are selected for potential inclusion in this document. Initial selection is based largely on DOE needs and procedure applicability and completeness. Methods appearing in this document are one of two types, {open_quotes}Draft{close_quotes} or {open_quotes}Verified{close_quotes}. {open_quotes}Draft{close_quotes} methods that have been reviewed internally and show potential for eventual verification are included in this document, but they have not been reviewed externally, and their precision and bias may not be known. {open_quotes}Verified{close_quotes} methods in DOE Methods have been reviewed by volunteers from various DOE sites and private corporations. These methods have delineated measures of precision and accuracy.

  16. Draft air deflecting device

    SciTech Connect

    Riley, J.E.

    1982-05-18

    A draft air deflecting device is mountable proximate to a window contained in a firebox and serves as a conduit which directs draft air across the inner surface of the window prior to its supporting combustion of the fuel in the firebox. In this respect , the draft air deflecting device is formed as a box which communicates with draft air holes located in the firebox and which includes a forwardly extending lip serving to define a nozzle for both increasing the velocity and directing the incoming draft air across the firebox window. The incoming draft air is thus utilized to cool and to prevent soot, creosote and other particulates from accumulating on the window.

  17. 78 FR 2396 - Draft Research Report: Investigation of Ground Water Contamination Near Pavillion, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... AGENCY Draft Research Report: Investigation of Ground Water Contamination Near Pavillion, WY AGENCY... announcing an extension to the public comment period for the external review of the draft research report titled, ``Investigation of Ground Water Contamination near Pavillion, Wyoming.'' The draft...

  18. 76 FR 38650 - Draft Integrated Science Assessment for Lead

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... AGENCY Draft Integrated Science Assessment for Lead AGENCY: Environmental Protection Agency. ACTION... Draft Integrated Science Assessment for Lead'' (EPA/600/R-10/075A). The original Federal Register notice... Development as part of the review of the National Ambient Air Quality Standards (NAAQS) for Lead. DATES:...

  19. 78 FR 15955 - Draft Guidance for Industry and Review Staff on Formal Dispute Resolution: Appeals Above the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ... review, CDER and CBER make a wide variety of scientific and procedural decisions that are critical to a... be precedent setting, it is critical that there be procedures in place to encourage open, prompt... represent the Agency's current thinking on formal dispute resolution regarding appeals above the...

  20. 76 FR 21736 - Draft Toxicological Review of Methanol (Non-Cancer) in Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ... Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of... Information on the Integrated Risk Information System (IRIS)'' is available primarily via the Internet on the... Review of Methanol (Non-Cancer): In Support of Summary Information on the Integrated Risk...

  1. Development of a Relative Potency Factor (Rpf) Approach for Polycyclic Aromatic Hydrocarbon (PAH) Mixtures (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of polycyclic aromatic hydrocarbon (PAH) mixtures that when finalized will appear on the Integrated Risk Information System (IRIS) database. ...

  2. The Effects of Mountaintop Mines and Valley Fills on Aquatic Ecosystems of the Central Appalachian Coalfields (External Review Draft)

    EPA Science Inventory

    This report assesses the state of the science on the environmental impacts of mountaintop mines and valley fills (MTM-VF) on streams in the Central Appalachian Coalfields. Our review focused on the aquatic impacts of mountaintop removal coal mining, which, as its name suggests, ...

  3. Assessment of the Potential Impacts of Hydraulic Fracturing for Oil and Gas on Drinking Water Resources (External Review Draft)

    EPA Science Inventory

    This assessment provides a review and synthesis of available scientific literature and data to assess the potential for hydraulic fracturing for oil and gas to impact the quality or quantity of drinking water resources, and identifies factors affecting the frequency or severity o...

  4. Sage-Grouse Lek Guideline Review Report

    SciTech Connect

    John Reisenauer

    2011-05-01

    On April 21, 2011, an Idaho National Laboratory (INL) Land Use Committee meeting was convened to support a Department of Energy Idaho Operations Office (DOE-ID) unofficial request to obtain Land Use Committee comments pertaining to the proposed Sage-Grouse Breeding Habitat Regulations. Two documents were provided from DOE-ID pertaining to the proposed regulations: “Guidelines for INL Site Activities within Sage-grouse Breeding Habitat” and “Guidelines for New Infrastructure Development and Future Activities on the INL Site.” The INL Land Use Committee agreed to conduct this unofficial review in the spirit of collaboration between DOE-ID and the INL Land Use Committee. However, through this cursory review, significant concerns were raised regarding the guidelines, INL financial obligations, and the draft Candidate Conservation Agreement, which was not part of the requested review but is referred to by the guideline. Therefore, it is the position of the INL Land Use Committee, based on the issues raised in its cursory review, that DOE-ID request INL (through contractual channels) to conduct a formal review of the draft Candidate Conservation Agreement and guidelines. A formal review would allow ample time to thoroughly review the extensive draft regulations, identify areas of concern, and establish impacts (e.g., cost and project delays).

  5. Supplement to the Surplus Plutonium Disposition Draft Environmental Impact Statement

    SciTech Connect

    N /A

    1999-05-14

    the environmental review specified in DOE's NEPA regulations in 10 CFR 1021.216. The six reactors selected are Catawba Nuclear Station Units 1 and 2 in South Carolina McGuire Nuclear Station Units 1 and 2 in North Carolina, and North Anna Power Station Units 1 and 2 in Virginia. The Supplement describes the potential environmental impacts of using MOX fuel in these six specific reactors named in the DCS proposal as well as other program changes made since the SPD Draft EIS was published.

  6. Draft environmental assessment: Davis Canyon site, Utah. Nuclear Waste Policy Act (Section 112). [Contains glossary

    SciTech Connect

    Not Available

    1984-12-01

    In February 1983, the US Department of Energy (DOE) identified the Davis Canyon site in Utah, as one of nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. To determine their suitability, the Davis Canyon site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for Nuclear Waste Repositories. These evaluations are reported in this draft environmental assessment (EA), which is being issued for public review and comment. The DOE findings and determinations that are based on these evaluations are preliminary and subject to public review and comment. A final EA will be prepared after considering the comments received. On the basis of the evaluations reported in this draft EA, the DOE has found that the Davis Canyon site is not disqualified under the guidelines. The site is in the Paradox Basin, which is one of five distinct geohydrologic settings considered for the first repository. This setting contains one other potentially acceptable site - the Lavender Canyon site. Although the Lavender Canyon site appears to be suitable for site characterization, the DOE has concluded that the Davis Canyon site is the preferred site in the Paradox Basin. Furthermore, the DOE finds that the site is suitable for site characterization because the evidence does not support a conclusion that the site will not be able to meet each of the qualifying conditions specified in the guidelines. On the basis of these findings, the DOE is proposing to nominate the Davis Canyon site as one of five sites suitable for characterization. Having compared the Davis Canyon site with the other four sites proposed for nomination, the DOE has determined that the Davis Canyon site is not one of the three preferred sites for recommendation to the President as candidates for characterization.

  7. Proceedings of the 1998 U.S. DOE Hydrogen Program Review: Volume 2

    SciTech Connect

    1998-08-01

    This document contains technical progress reports on 42 research projects funded by the DOE Hydrogen Program in Fiscal Year 1998, in support of its mission to make hydrogen a cost-effective energy carrier for utility, building, and transportation applications. Each year, the Program conducts a rigorous review of its portfolio of projects, utilizing teams of experts to provide vital feedback on the progress of research. These proceedings serve as an important technology reference for the DOE Hydrogen Program. The papers in Volume 2 are arranged under the following topical sections: Storage and separation systems; Thermal systems; and Transportation systems. Selected papers have been indexed separately for inclusion in the Energy Science and Technology Database.

  8. Draft environmental assessment: Deaf Smith County site, Texas. Nuclear Waste Policy Act (Section 112). [Contains Glossary

    SciTech Connect

    Not Available

    1984-12-01

    In February 1983, the US Department of Energy identified a location in Deaf Smith County, Texas, as one of nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. The potentially acceptable site was subsequently narrowed to an area of 9 square miles. To determine their suitability, the Deaf Smith site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for Nuclear Waste Repositories. These evaluations are reported in this draft environmental assessment, which is being issued for public review and comment. The DOE findings and determinations that are based on these evaluations are preliminary and subject to public review and comment. A final EA will be prepared after considering the comments received. On the basis of the evaluations reported in this draft EA, the DOE has found that the Deaf Smith site is not disqualified under the guidelines. The site is in the Permian Basin, which is one of five distinct geohydrologic settings considered for the first repository. This setting contains one other potentially acceptable site - the Swisher site. Although the Swisher site appears to be suitable for site characterization, DOE has concluded that the Deaf Smith site is the preferred site. The DOE finds that the site is suitable for site characterization because the evidence does not support a conclusion that the site will not be able to meet each of the qualifying conditions specified in the guidelines. On the basis of these findings, the DOE is proposing to nominate the Deaf Smith site as one of five sites suitable for characterization. Having compared the Deaf Smith site with the other four sites proposed for nomination, the DOE has determined that the Deaf Smith site is one of the three preferred sites for recommendation to the President as candidates for characterization.

  9. A Review of Training Methods and Instructional Techniques: Implications for Behavioral Skills Training in U.S. Astronauts (DRAFT)

    NASA Technical Reports Server (NTRS)

    Hysong, Sylvia J.; Galarza, Laura; Holland, Albert W.

    2007-01-01

    Long-duration space missions (LDM) place unique physical, environmental and psychological demands on crewmembers that directly affect their ability to live and work in space. A growing body of research on crews working for extended periods in isolated, confined environments reveals the existence of psychological and performance problems in varying degrees of magnitude. The research has also demonstrated that although the environment plays a cathartic role, many of these problems are due to interpersonal frictions (Wood, Lugg, Hysong, & Harm, 1999), and affect each individual differently. Consequently, crewmembers often turn to maladaptive behaviors as coping mechanisms, resulting in decreased productivity and psychological discomfort. From this body of research, critical skills have been identified that can help a crewmember better navigate the psychological challenges of long duration space flight. Although most people lack several of these skills, most of them can be learned; thus, a training program can be designed to teach crewmembers effective leadership, teamwork, and self-care strategies that will help minimize the emergence of maladaptive behaviors. Thus, it is the purpose of this report is twofold: 1) To review the training literature to help determine the optimal instructional methods to use in delivering psychological skill training to the U.S. Astronaut Expedition Corps, and 2) To detail the structure and content of the proposed Astronaut Expedition Corps Psychological Training Program.

  10. 77 FR 46518 - Draft Resource Management Plan/General Plan Draft Environmental Impact Statement/Revised Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    .../Revised Draft Environmental Impact Report for the San Luis Reservoir State Recreation Area, Merced County... available for public review and comment the San Luis Reservoir State Recreation Area Resource Management... meeting will be held at the San Luis Reservoir State Recreation Area Headquarters, 31426 Gonzaga...

  11. Does salmon calcitonin cause cancer? A review and meta-analysis.

    PubMed

    Wells, G; Chernoff, J; Gilligan, J P; Krause, D S

    2016-01-01

    Recently an association between the use of calcitonin and cancer has been postulated. We reviewed the biological rationale and performed an additional analysis of historical data with respect to the possibility. An association cannot be excluded, but the relationship is weak and causality is unlikely. The purpose of the present study is to review the strength of association and likelihood of a causal relationship between use of calcitonin and cancer. We reviewed the evidence for this association, including the molecular signaling mechanisms of calcitonin, preclinical data, an "experiment of nature," and the results of a previous meta-analysis which showed a weak association. We performed an additional meta-analysis to incorporate the data from a novel investigational oral formulation of salmon calcitonin. Review of the literature did not identify a cellular signaling mechanism of action which might account for a causal relationship or toxicologic or postmarketing data to support the thesis. Additional clinical results incorporated into previous meta-analyses weakened but did not completely negate the possibility of association. A causal association between calcitonin use and malignancy is unlikely, as there is little biological plausibility. The preponderance of nonclinical and clinical evidence also does not favor a causal relationship.

  12. Career Directions for Drafting CAD Technicians.

    ERIC Educational Resources Information Center

    Moore, Pam

    2002-01-01

    Provides information careers for drafting/computer-assisted drafting technicians, including salaries, responsibilities, employment outlook, working conditions, skills needed, and career advancement opportunities. Lists professional drafting organizations. (JOW)

  13. Executive Summary, Hydraulic Fracturing Study - Draft Assessment 2015

    EPA Pesticide Factsheets

    In this Executive Summary of the HF Draft report, EPA highlights the reviews of scientific literature to assess the potential for hydraulic fracturing for oil and gas to change the quality or quantity of drinking water resources.

  14. 46 CFR 169.755 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... stem and upon the sternpost or rudderpost or at any place at the stern of the vessel as may be... where the keel does not extend forward or aft to the location of the draft marks, due to a raked stem...

  15. 78 FR 39253 - Notice of Extension of Comment Period for Draft Initial Comprehensive Plan and Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ...] Notice of Extension of Comment Period for Draft Initial Comprehensive Plan and Draft Environmental... Public Comment Period. SUMMARY: Pursuant to the Resources and Ecosystems Sustainability, Tourist... region and the Draft Programmatic Environmental Assessment (Draft PEA) for the Draft Plan....

  16. Nanomaterial Case Study: A Comparison of Multiwalled Carbon Nanotube and Decabromodiphenyl Ether Flame-Retardant Coatings Applied to Upholstery Textiles (External Review Draft)

    EPA Science Inventory

    The draft document is intended to be used as part of a process to identify what is known and, more importantly, what is not yet known that could be of value in assessing the broad implications of specific nanomaterials. Like previous case studies (see History/ Chronology below), ...

  17. Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) (Version 2) (External Review Draft)

    EPA Science Inventory

    EPA announced the availability of the draft report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) for a 30-day public comment period. The ICLUS version 2 (v2) modeling tool furthered land change mod...

  18. An Approach to Using Toxicogenomic Data in U.S. EPA Human Health Risk Assessments: A Dibutyl Phthalate (Dbp) Case Study (External Review Draft)

    EPA Science Inventory

    This draft report is a description of an approach to evaluate genomic data for use in risk assessment and a case study to illustrate the approach. The dibutyl phthalate (DBP) case study example focuses on male reproductive developmental effects and the qualitative application of...

  19. Human-factors control-room-design review draft audit report: Detroit Edison Company, Enrico Fermi Atomic Power Plant--Unit 2

    SciTech Connect

    Savage, J.W.

    1981-08-12

    A human factors audit of the Fermi-2 control room was conducted April 27 through May 1, 1981. This report contains the audit team findings, organized according to the draft NUREG-0700 guidelines sections. The discrepancies identified during the audit are categorized according to their severity and the required schedule for their resolution.

  20. Integrated Science Assessment (ISA) for Oxides of Nitrogen, Oxides of Sulfur and Particulate Matter - Ecological Criteria (First External Review Draft, Mar 2017)

    EPA Science Inventory

    This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision on retaining or revising the current secondary standards for NO2, SO2, PM 2.5 and PM 10 since the prior re...

  1. Vulnerability Assessments in Support of the Climate Ready Estuaries Program: A Novel Approach Using Expert Judgment, Volume I: Results for the San Francisco Estuary Partnership (External Review Draft)

    EPA Science Inventory

    As part of the Climate Ready Estuaries (CRE) program, the Global Change Research Program (GCRP) in the National Center for Environmental Assessment, Office of Research and Development at the U.S. Environmental Protection Agency has prepared this draft report exploring a new metho...

  2. AN APPROACH TO USING TOXICOGENOMIC DATA IN U.S. EPA HUMAN HEALTH RISK ASSESSMENTS: A DIBUTYL PHTHALATE (DBP) CASE STUDY (EXTERNAL REVIEW DRAFT)

    EPA Science Inventory

    This draft report is a description of an approach to evaluate genomic data for use in risk assessment and a case study to illustrate the approach. The dibutyl phthalate (DBP) case study example focuses on male reproductive developmental effects and the qualitative application of...

  3. Draft Test Guideline: Gammarid Acute Toxicity Test

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  4. Draft Test Guideline: Penaeid Acute Toxicity Test

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  5. Draft Test Guideline: Aquatic Food Chain Transfer

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  6. Draft Test Guideline: Fish Life Cycle Toxicity

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  7. Draft Test Guideline: Daphnid Chronic Toxicity Test

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  8. Draft Test Guideline: Chironomid Sediment Toxicity Test

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  9. Draft Test Guideline: Mysid Chronic Toxicity Test

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  10. Draft Test Guideline: Oyster Bioconcentration Factor (BCF)

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  11. Draft Test Guideline: Mysid Acute Toxicity Test

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  12. Draft Test Guideline: Fish Bioconcentration Factor (BCF)

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  13. 36 CFR 1260.60 - How does the NDC facilitate systematic review of records exempted at the individual record or...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... systematic review of records exempted at the individual record or file series level? 1260.60 Section 1260.60... DECLASSIFICATION OF NATIONAL SECURITY INFORMATION Systematic Declassification § 1260.60 How does the NDC facilitate systematic review of records exempted at the individual record or file series level? (a) NARA, through...

  14. 36 CFR 1260.60 - How does the NDC facilitate systematic review of records exempted at the individual record or...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... systematic review of records exempted at the individual record or file series level? 1260.60 Section 1260.60... DECLASSIFICATION OF NATIONAL SECURITY INFORMATION Systematic Declassification § 1260.60 How does the NDC facilitate systematic review of records exempted at the individual record or file series level? (a) NARA, through...

  15. 36 CFR 1260.60 - How does the NDC facilitate systematic review of records exempted at the individual record or...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... systematic review of records exempted at the individual record or file series level? 1260.60 Section 1260.60... DECLASSIFICATION OF NATIONAL SECURITY INFORMATION Systematic Declassification § 1260.60 How does the NDC facilitate systematic review of records exempted at the individual record or file series level? (a) NARA, through...

  16. Cluster: Drafting. Course: Architectural Drafting. Research Project.

    ERIC Educational Resources Information Center

    Sanford - Lee County Schools, NC.

    The sequence of 10 units is designed for use with an instructor in architectural drafting, and is also keyed to other texts. Each unit contains several task packages specifying prerequisites, rationale for learning, objectives, learning activities to be supervised by the instructor, and learning practice. The units cover: architectural lettering…

  17. Aeronautical Drafting, Drafting 3: 9257.02.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    Intended for students interested in the aircraft and missile field of engineering and drafting, the course covers fundamentals, working drawings, and auxiliary views and sections that are related to this field. Considered advanced training, a prerequisite for the course is mastery of the skills indicated in Electrical and Electronic…

  18. Does yoga therapy reduce blood pressure in patients with hypertension?: an integrative review.

    PubMed

    Okonta, Nkechi Rose

    2012-01-01

    The aim of this article was to present a evidence-based integrative research review that validates yoga therapy as an effective complementary treatment in the management of high blood pressure (BP). The article also uses the theoretical framework of Dr Hans Selye's general adaptation syndrome. Yoga researchers demonstrate that yoga works because it modulates the physiological system of the body, specifically its effect on the heart rate. This review is significant because yoga presents an effective method of treating hypertension that is nonpharmacologic and therefore there are no adverse effects and there are other valuable health benefits. Research suggests that stress is a contributing factor to high BP; hence, the use of the general adaptation syndrome and the most important attribute of yoga, that is, it is a physical and mental exercise program, that is in sync with the philosophy of holistic nursing care where one treats the whole individual and not just the disease. The review was conducted with a search of computerized databases such as OVID, Academic Search Premier, CINAHL, MEDLINE, and Health Source: Nursing/Academic edition, PsychINFO, as well as reliable Web sites such as the cdc.gov, among others. An integrative review search was conducted, and 10 studies met the inclusion criteria. They include a combination of randomized controlled trials, quasi-experimental studies, and pilot studies. Yoga therapy is a multifunctional exercise modality with numerous benefits. Not only does yoga reduce high BP but it has also been demonstrated to effectively reduce blood glucose level, cholesterol level, and body weight, major problems affecting the American society. The completed integrative review provides guidelines for nursing implementation as a complementary treatment of high BP.

  19. Carbapenem stewardship: does ertapenem affect Pseudomonas susceptibility to other carbapenems? A review of the evidence.

    PubMed

    Nicolau, David P; Carmeli, Yehuda; Crank, Christopher W; Goff, Debra A; Graber, Christopher J; Lima, Ana Lucia L; Goldstein, Ellie J C

    2012-01-01

    The group 2 carbapenems (imipenem, meropenem and, more recently, doripenem) have been a mainstay of treatment for patients with serious hospital infections caused by Pseudomonas aeruginosa, Enterobacteriaceae and other difficult-to-treat Gram-negative pathogens as well as mixed aerobic/anaerobic infections. When ertapenem, a group 1 carbapenem, was introduced, questions were raised about the potential for ertapenem to select for imipenem- and meropenem-resistant Pseudomonas. Results from ten clinical studies evaluating the effect of ertapenem use on the susceptibility of Pseudomonas to carbapenems have uniformly shown that ertapenem use does not result in decreased Pseudomonas susceptibility to these antipseudomonal carbapenems. Here we review these studies evaluating the evidence of how ertapenem use affects P. aeruginosa as well as provide considerations for ertapenem use in the context of institutional stewardship initiatives.

  20. Delegation of Authority to Review Leases of Property at Department of Energy Weapon Production Facilities Under the Department of Energy Organization Act

    EPA Pesticide Factsheets

    The purpose of this memorandum is to request that the Human Resources Staff for OSWER and OECA start the Green Border review process for the attached draft delegation of authority, which delegates the authority of the Administrator to review leases of property at Department of Energy (DOE) weapon production facilities to the Assistant Administrator for OSWER and Regional Administrators.

  1. Wackenhut Services, Incorporated: Report from the DOE Voluntary Protection Program onsite review, August 10--14, 1998

    SciTech Connect

    1999-05-01

    This report summarizes the Department of Energy Voluntary Protection Program (DOE-VPP) Review Team`s findings from the five-day onsite evaluation of Wackenhut Services, Inc. (WSI) at Savannah River Site (SRS), conducted August 10-14, 1998. The site was evaluated against the program requirements contained in US Department of Energy Voluntary Protection Program, Part 1: Program Elements to determine its success in implementing the five DOE-VPP tenets. The Team determined that WSI has met in varying degrees, all the tenets of the DOE-VPP. In every case, WSI programs and procedures exceed the level or degree necessary for compliance with existing standards, DOE Orders, and guidelines. In addition, WSI has systematically integrated their occupational safety and health (OSH) program into management and work practices at all levels. WSI`s efforts toward implementing the five major DOE-VPP tenets are summarized.

  2. Does public health advocacy seek to redress health inequities? A scoping review.

    PubMed

    Cohen, Benita E; Marshall, Shelley G

    2017-03-01

    The public health (PH) sector is ideally situated to take a lead advocacy role in catalysing and guiding multi-sectoral action to address social determinants of health inequities, but evidence suggests that PH's advocacy role has not been fully realised. The purpose of this review was to determine the extent to which the PH advocacy literature addresses the goal of reducing health and social inequities, and to increase understanding of contextual factors shaping the discourse and practice of PH advocacy. We employed scoping review methods to systematically examine and chart peer-reviewed and grey literature on PH advocacy published from January 1, 2000 to June 30, 2015. Databases and search engines used included: PubMed, CINAHL, PsycINFO, Social Sciences Citation Index, Google Scholar, Google, Google Books, ProQuest Dissertations and Theses, Grey Literature Report. A total of 183 documents were charted, and included in the final analysis. Thematic analysis was both inductive and deductive according to the objectives. Although PH advocacy to address root causes of health inequities is supported theoretically and through professional practice standards, the empirical literature does not reflect that this is occurring widely in PH practice. Tensions within the discourse were noted and multiple barriers to engaging in PH advocacy for health equity were identified, including a preoccupation with individual responsibilities for healthy lifestyles and behaviours, consistent with the emergence of neoliberal governance. If the PH sector is to fulfil its advocacy role in catalysing action to reduce health inequities, it will be necessary to address advocacy barriers at multiple levels, promote multi-sectoral efforts that implicate the state and corporations in the production of health inequities, and rally state involvement to redress these injustices.

  3. Does Carbohydrate Intake During Endurance Running Improve Performance? A Critical Review.

    PubMed

    Wilson, Patrick B

    2016-12-01

    Wilson, PB. Does carbohydrate intake during endurance running improve performance? A critical review. J Strength Cond Res 30(12): 3539-3559, 2016-Previous review articles assessing the effects of carbohydrate ingestion during prolonged exercise have not focused on running. Given the popularity of distance running and the widespread use of carbohydrate supplements, this article reviewed the evidence for carbohydrate ingestion during endurance running. The criteria for inclusion were (a) experimental studies reported in English language including a performance task, (b) moderate-to-high intensity exercise >60 minutes (intermittent excluded), and (c) carbohydrate ingestion (mouth rinsing excluded). Thirty studies were identified with 76 women and 505 men. Thirteen of the 17 studies comparing a carbohydrate beverage(s) with water or a placebo found a between-condition performance benefit with carbohydrate, although heterogeneity in protocols precludes clear generalizations about the expected effect sizes. Additional evidence suggests that (a) performance benefits are most likely to occur during events >2 hours, although several studies showed benefits for tasks lasting 90-120 minutes; (b) consuming carbohydrate beverages above ad libitum levels increases gastrointestinal discomfort without improving performance; (c) carbohydrate gels do not influence performance for events lasting 16-21 km; and (d) multiple saccharides may benefit events >2 hours if intake is ≥1.3 g·min Given that most participants were fasted young men, inferences regarding women, adolescents, older runners, and those competing in fed conditions are hampered. Future studies should address these limitations to further elucidate the role of carbohydrate ingestion during endurance running.

  4. 76 FR 10342 - Availability of Fiscal Years 2011-2016 Draft Strategic Plan and Request for Public Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Availability of Fiscal Years 2011-2016 Draft Strategic Plan and Request for Public Comment AGENCY: Department of Energy (DOE). ACTION: Notice of availability of DOE's Draft Strategic Plan and request for...

  5. Public Review Draft: A Method for Assessing Carbon Stocks, Carbon Sequestration, and Greenhouse-Gas Fluxes in Ecosystems of the United States Under Present Conditions and Future Scenarios

    USGS Publications Warehouse

    Bergamaschi, Brian A.; Bernknopf, Richard; Clow, David; Dye, Dennis; Faulkner, Stephen; Forney, William; Gleason, Robert; Hawbaker, Todd; Liu, Jinxun; Liu, Shu-Guang; Prisley, Stephen; Reed, Bradley; Reeves, Matthew; Rollins, Matthew; Sleeter, Benjamin; Sohl, Terry; Stackpoole, Sarah; Stehman, Stephen; Striegl, Robert G.; Wein, Anne; Zhu, Zhi-Liang; Zhu, Zhi-Liang

    2010-01-01

    The Energy Independence and Security Act of 2007 (EISA), Section 712, authorizes the U.S. Department of the Interior to develop a methodology and conduct an assessment of the Nation's ecosystems focusing on carbon stocks, carbon sequestration, and emissions of three greenhouse gases (GHGs): carbon dioxide, methane, and nitrous oxide. The major requirements include (1) an assessment of all ecosystems (terrestrial systems, such as forests, croplands, wetlands, shrub and grasslands; and aquatic ecosystems, such as rivers, lakes, and estuaries), (2) an estimation of annual potential capacities of ecosystems to increase carbon sequestration and reduce net GHG emissions in the context of mitigation strategies (including management and restoration activities), and (3) an evaluation of the effects of controlling processes, such as climate change, land use and land cover, and wildlfires. The purpose of this draft methodology for public review is to propose a technical plan to conduct the assessment. Within the methodology, the concepts of ecosystems, carbon pools, and GHG fluxes used for the assessment follow conventional definitions in use by major national and international assessment or inventory efforts. In order to estimate current ecosystem carbon stocks and GHG fluxes and to understand the potential capacity and effects of mitigation strategies, the method will use two time periods for the assessment: 2001 through 2010, which establishes a current ecosystem GHG baseline and will be used to validate the models; and 2011 through 2050, which will be used to assess future potential conditions based on a set of projected scenarios. The scenario framework is constructed using storylines of the Intergovernmental Panel on Climate Change (IPCC) Special Report Emission Scenarios (SRES), along with initial reference land-use and land-cover (LULC) and land-management scenarios. An additional three LULC and land-management mitigation scenarios will be constructed for each

  6. 78 FR 23926 - Extension of the Public Comment Period for the Draft Uranium Leasing Program Programmatic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Extension of the Public Comment Period for the Draft Uranium Leasing Program Programmatic Environmental...: The U.S. Department of Energy (DOE) is extending the public comment period for the Draft...

  7. Draft Genome Sequence of Erythromycin- and Oxytetracycline-Sensitive Nocardia seriolae Strain U-1 (NBRC 110359)

    PubMed Central

    Sukeda, Masaki; Shimizu, Masato; Yamane, Jin; Ohnishi, Kouhei; Oshima, Syun-ichirou

    2016-01-01

    In Japan, the emergence of macrolide- and oxytetracycline-resistant strains of Nocardia seriolae has previously been reported. Here, we describe the draft genome sequence of N. seriolae strain U-1, isolated in 2011 from a diseased yellowtail in Kagoshima Prefecture. The draft genome does not have any genes responsible for macrolide and tetracycline resistance. PMID:26798107

  8. Uranium-Bearing Evaporite Mineralization Influencing Plume Persistence. Literature Review and DOE-LM Site Surveys

    SciTech Connect

    None, None

    2016-05-01

    This report on evaporite mineralization was completed as an Ancillary Work Plan for the Applied Studies and Technology program under the U.S. Department of Energy (DOE) Office of Legacy Management (LM). This study reviews all LM sites under Title I and Title II of the Uranium Mill Tailings Radiation Control Act (UMTRCA) and one Decontamination and Decommissioning site to provide (1) a summary of which sites have evaporite deposits, (2) any available quantitative geochemical and mineralogical analyses, and (3) references to relevant reports. In this study, “evaporite” refers to any secondary mineral precipitate that occurs due to a loss of water through evaporative processes. This includes efflorescent salt crusts, where this term refers to a migration of dissolved constituents to the surface with a resulting salt crust, where “salt” can refer to any secondary precipitate, regardless of constituents. The potential for the formation of evaporites at LM sites has been identified, and may have relevance to plume persistence issues. Evaporite deposits have the potential to concentrate and store contaminants at LM sites that could later be re-released. These deposits can also provide a temporary storage mechanism for carbonate, chloride, and sulfate salts along with uranium and other contaminants of concern (COCs). Identification of sites with evaporites will be used in a new technical task plan (TTP), Persistent Secondary Contaminant Sources (PeSCS), for any proposed additional sampling and analyses. This additional study is currently under development and will focus on determining if the dissolution of evaporites has the potential to hinder natural flushing strategies and impact plume persistence. This report provides an initial literature review on evaporites followed by details for each site with identified evaporites. The final summary includes a table listing of all relevant LM sites regardless of evaporite identification.

  9. How Does the Tobacco Industry Attempt to Influence Marketing Regulations? A Systematic Review

    PubMed Central

    Savell, Emily; Gilmore, Anna B.; Fooks, Gary

    2014-01-01

    Background The Framework Convention on Tobacco Control makes a number of recommendations aimed at restricting the marketing of tobacco products. Tobacco industry political activity has been identified as an obstacle to Parties’ development and implementation of these provisions. This study systematically reviews the existing literature on tobacco industry efforts to influence marketing regulations and develops taxonomies of 1) industry strategies and tactics and 2) industry frames and arguments. Methods Searches were conducted between April-July 2011, and updated in March 2013. Articles were included if they made reference to tobacco industry efforts to influence marketing regulations; supported claims with verifiable evidence; were written in English; and concerned the period 1990–2013. 48 articles met the review criteria. Narrative synthesis was used to combine the evidence. Results 56% of articles focused on activity in North America, Europe or Australasia, the rest focusing on Asia (17%), South America, Africa or transnational activity. Six main political strategies and four main frames were identified. The tobacco industry frequently claims that the proposed policy will have negative unintended consequences, that there are legal barriers to regulation, and that the regulation is unnecessary because, for example, industry does not market to youth or adheres to a voluntary code. The industry primarily conveys these arguments through direct and indirect lobbying, the promotion of voluntary codes and alternative policies, and the formation of alliances with other industrial sectors. The majority of tactics and arguments were used in multiple jurisdictions. Conclusions Tobacco industry political activity is far more diverse than suggested by existing taxonomies of corporate political activity. Tactics and arguments are repeated across jurisdictions, suggesting that the taxonomies of industry tactics and arguments developed in this paper are generalisable to

  10. 34 CFR 462.12 - What procedures does the Secretary use to review the suitability of tests?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What procedures does the Secretary use to review the suitability of tests? 462.12 Section 462.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION...

  11. 34 CFR 462.12 - What procedures does the Secretary use to review the suitability of tests?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What procedures does the Secretary use to review the suitability of tests? 462.12 Section 462.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION...

  12. 34 CFR 462.12 - What procedures does the Secretary use to review the suitability of tests?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What procedures does the Secretary use to review the suitability of tests? 462.12 Section 462.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION...

  13. 34 CFR 462.12 - What procedures does the Secretary use to review the suitability of tests?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What procedures does the Secretary use to review the suitability of tests? 462.12 Section 462.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION...

  14. 34 CFR 462.12 - What procedures does the Secretary use to review the suitability of tests?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What procedures does the Secretary use to review the suitability of tests? 462.12 Section 462.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION...

  15. Does alcohol have any effect on male reproductive function? A review of literature.

    PubMed

    La Vignera, Sandro; Condorelli, Rosita A; Balercia, Giancarlo; Vicari, Enzo; Calogero, Aldo E

    2013-03-01

    Although alcohol is widely used, its impact on the male reproductive function is still controversial. Over the years, many studies have investigated the effects of alcohol consumption on sperm parameters and male infertility. This article reviews the main preclinical and clinical evidences. Studies conducted on the experimental animal have shown that a diet enriched with ethanol causes sperm parameter abnormalities, a number of alterations involving the reproductive tract inhibition, and reduced mouse oocyte in vitro fertilization rate. These effects were partly reversible upon discontinuation of alcohol consumption. Most of the studies evaluating the effects of alcohol in men have shown a negative impact on the sperm parameters. This has been reported to be associated with hypotestosteronemia and low-normal or elevated gonadotropin levels suggesting a combined central and testicular detrimental effect of alcohol. Nevertheless, alcohol consumption does not seem to have much effect on fertility either in in vitro fertilization programs or population-based studies. Finally, the genetic background and other concomitant, alcohol consumption-related conditions influence the degree of the testicular damage. In conclusion, alcohol consumption is associated with a deterioration of sperm parameters which may be partially reversible upon alcohol consumption discontinuation.

  16. Does Oxytocin Increase Trust in Humans? A Critical Review of Research.

    PubMed

    Nave, Gideon; Camerer, Colin; McCullough, Michael

    2015-11-01

    Behavioral neuroscientists have shown that the neuropeptide oxytocin (OT) plays a key role in social attachment and affiliation in nonhuman mammals. Inspired by this initial research, many social scientists proceeded to examine the associations of OT with trust in humans over the past decade. To conduct this work, they have (a) examined the effects of exogenous OT increase caused by intranasal administration on trusting behavior, (b) correlated individual difference measures of OT plasma levels with measures of trust, and (c) searched for genetic polymorphisms of the OT receptor gene that might be associated with trust. We discuss the different methods used by OT behavioral researchers and review evidence that links OT to trust in humans. Unfortunately, the simplest promising finding associating intranasal OT with higher trust has not replicated well. Moreover, the plasma OT evidence is flawed by how OT is measured in peripheral bodily fluids. Finally, in recent large-sample studies, researchers failed to find consistent associations of specific OT-related genetic polymorphisms and trust. We conclude that the cumulative evidence does not provide robust convergent evidence that human trust is reliably associated with OT (or caused by it). We end with constructive ideas for improving the robustness and rigor of OT research.

  17. Does Emotional Intelligence have a “Dark” Side? A Review of the Literature

    PubMed Central

    Davis, Sarah K.; Nichols, Rachel

    2016-01-01

    Emotional intelligence (EI) was once touted as the panacea for a satisfying and successful life. Consequently, there has been much emphasis on developing interventions to promote this personal resource in applied settings. Despite this, a growing body of research has begun to identify particular contexts when EI does not appear helpful and may even be deleterious to a person, or those they have contact with, suggesting a “dark” side to the construct. This paper provides a review of emergent literature to examine when, why and how trait and ability EI may contribute to negative intrapersonal (psychological ill-health; stress reactivity) and interpersonal outcomes (emotional manipulation; antisocial behavior). Negative effects were found to operate across multiple contexts (health, academic, occupational) however these were often indirect, suggesting that outcomes depend on pre-existing qualities of the person. Literature also points to the possibility of “optimal” levels of EI—both within and across EI constructs. Uneven profiles of self-perceptions (trait facets) or actual emotional skills contribute to poorer outcomes, particularly emotional awareness, and management. Moreover, individuals who possess high levels of skill but have lower self-perceptions of their abilities fare worse that those with more balanced profiles. Future research must now improve methodological and statistical practices to better capture EI in context and the negative corollary associated with high levels. PMID:27625627

  18. Why does my shoulder hurt? A review of the neuroanatomical and biochemical basis of shoulder pain.

    PubMed

    Dean, Benjamin John Floyd; Gwilym, Stephen Edward; Carr, Andrew Jonathan

    2013-11-01

    If a patient asks 'why does my shoulder hurt?' the conversation will quickly turn to scientific theory and sometimes unsubstantiated conjecture. Frequently, the clinician becomes aware of the limits of the scientific basis of their explanation, demonstrating the incompleteness of our understanding of the nature of shoulder pain. This review takes a systematic approach to help answer fundamental questions relating to shoulder pain, with a view to providing insights into future research and novel methods for treating shoulder pain. We shall explore the roles of (1) the peripheral receptors, (2) peripheral pain processing or 'nociception', (3) the spinal cord, (4) the brain, (5) the location of receptors in the shoulder and (6) the neural anatomy of the shoulder. We also consider how these factors might contribute to the variability in the clinical presentation, the diagnosis and the treatment of shoulder pain. In this way we aim to provide an overview of the component parts of the peripheral pain detection system and central pain processing mechanisms in shoulder pain that interact to produce clinical pain.

  19. Does alcohol have any effect on male reproductive function? A review of literature

    PubMed Central

    La Vignera, Sandro; Condorelli, Rosita A; Balercia, Giancarlo; Vicari, Enzo; Calogero, Aldo E

    2013-01-01

    Although alcohol is widely used, its impact on the male reproductive function is still controversial. Over the years, many studies have investigated the effects of alcohol consumption on sperm parameters and male infertility. This article reviews the main preclinical and clinical evidences. Studies conducted on the experimental animal have shown that a diet enriched with ethanol causes sperm parameter abnormalities, a number of alterations involving the reproductive tract inhibition, and reduced mouse oocyte in vitro fertilization rate. These effects were partly reversible upon discontinuation of alcohol consumption. Most of the studies evaluating the effects of alcohol in men have shown a negative impact on the sperm parameters. This has been reported to be associated with hypotestosteronemia and low–normal or elevated gonadotropin levels suggesting a combined central and testicular detrimental effect of alcohol. Nevertheless, alcohol consumption does not seem to have much effect on fertility either in in vitro fertilization programs or population-based studies. Finally, the genetic background and other concomitant, alcohol consumption-related conditions influence the degree of the testicular damage. In conclusion, alcohol consumption is associated with a deterioration of sperm parameters which may be partially reversible upon alcohol consumption discontinuation. PMID:23274392

  20. Review of processes for the release of DOE real and non-real property for reuse and recycle

    SciTech Connect

    Ranek, N.L.; Kamboj, S.; Hensley, J.; Chen, S.Y.; Blunt, D.

    1997-11-01

    This report summarizes the underlying historical and regulatory framework supporting the concept of authorizing release for restricted or unrestricted reuse or recycle of real and non-real U.S. Department of Energy (DOE) properties containing residual radioactive material. Basic radiation protection principles as recommended by the International Commission on Radiological Protection are reviewed, and international initiatives to investigate radiological clearance criteria are reported. Applicable requirements of the U.S. Nuclear Regulatory Commission, the Environmental Protection Agency, DOE, and the State of Washington are discussed. Several processes that have been developed for establishing cleanup and release criteria for real and non-real DOE property containing residual radioactive material are presented. Examples of DOE real property for which radiological cleanup criteria were established to support unrestricted release are provided. Properties discussed include Formerly Utilized Sites Remedial Action Project sites, Uranium Mill Tailings Remedial Action Project sites, the Shippingport decommissioning project, the south-middle and south-east vaults in the 317 area at Argonne National Laboratory, the Heavy Water Components Test Reactor at DOE`s Savannah River Site, the Experimental Boiling Water Reactor at Argonne National Laboratory, and the Weldon Spring site. Some examples of non-real property for which DOE sites have established criteria to support unrestricted release are also furnished. 10 figs., 4 tabs.

  1. Weldon Spring Site Remedial Action Project: Report from the DOE voluntary protection program onsite review, November 17--21, 1997

    SciTech Connect

    1998-01-28

    This report summarizes the Department of Energy Voluntary Protection Program (DOE-VPP) Review Team`s findings from the five-day onsite evaluation of the Weldon Spring Site Remedial Action Project (WSSRAP), conducted November 17--21, 1997. The site was evaluated against the program requirements contained in ``US Department of Energy Voluntary Protection Program, Part 1: Program Elements`` to determine its success in implementing the five tenets of DOE-VPP. DOE-VPP consists of three programs, with names and functions similar to those in OSHA`s VPP. These programs are STAR, MERIT, and DEMONSTRATION. The STAR program is the core of DOE-VPP. The program is aimed at truly outstanding protectors of employee safety and health. The MERIT program is a steppingstone for contractors and subcontractors that have good safety and health programs but need time and DOE guidance to achieve STAR status. The DEMONSTRATION program is rarely used; it allows DOE to recognize achievements in unusual situations about which DOE needs to learn more before determining approval requirements for the STAR status.

  2. IRIS Toxicological Review of Beryllium and Compounds (2008 ...

    EPA Pesticide Factsheets

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Beryllium that when finalized will appear on the Integrated Risk Information System (IRIS) database. An IRIS Toxicological Review of Beryllium and Compounds was published in 1988 and reassessed in 1998. The current draft (2007) only focuses on the cancer assessment and does not re-evaluate posted reference doses or reference concentrations.

  3. Caught in the Draft

    ERIC Educational Resources Information Center

    Edge, Ron

    2007-01-01

    We've all seen (in movies, newscasts, or perhaps in person) the violent effect of the downwash that occurs when a helicopter hovers over the ground. Leaves, grass, and debris are dramatically blown about. We've also sat in front of circulating room fans and felt a large draft, whereas there seems to be very little air movement behind the fan. The…

  4. Does injury compensation lead to worse health after whiplash? A systematic review.

    PubMed

    Spearing, Natalie M; Connelly, Luke B; Gargett, Susan; Sterling, Michele

    2012-06-01

    One might expect that injury compensation would leave injured parties better off than they would otherwise have been, yet many believe that compensation does more harm than good. This study systematically reviews the evidence on this "compensation hypothesis" in relation to compensable whiplash injuries. PubMed, CINAHL, EMBASE, PEDro, PsycInfo, CCTR, Lexis, and EconLit were searched from the date of their inception to April 2010 to locate longitudinal studies, published in English, comparing the health outcomes of adults exposed/not exposed to compensation-related factors. Studies concerning serious neck injuries, using claimants only, or using proxy measures of health outcomes were excluded. Eleven studies were included. These examined the effect of lawyer involvement, litigation, claim submission, or previous claims on pain and other health outcomes. Among the 16 results reported were 9 statistically significant negative associations between compensation-related factors and health outcomes. Irrespective of the compensation-related factor involved and the health outcome measured, the quality of these studies was similar to studies that did not find a significant negative association: most took some measures to address selection bias, confounding, and measurement bias, and none resolved the potential for reverse causality bias that arises in the relationship between compensation-related factors and health. Unless ambiguous causal pathways are addressed, one cannot draw conclusions from statistical associations, regardless of their statistical significance and the extent of measures to address other sources of bias. Consequently, there is no clear evidence to support the idea that compensation and its related processes lead to worse health.

  5. Clinical review: Intra-abdominal hypertension: does it influence the physiology of prone ventilation?

    PubMed

    Kirkpatrick, Andrew W; Pelosi, Paolo; De Waele, Jan J; Malbrain, Manu Lng; Ball, Chad G; Meade, Maureen O; Stelfox, Henry T; Laupland, Kevin B

    2010-01-01

    Prone ventilation (PV) is a ventilatory strategy that frequently improves oxygenation and lung mechanics in critical illness, yet does not consistently improve survival. While the exact physiologic mechanisms related to these benefits remain unproven, one major theoretical mechanism relates to reducing the abdominal encroachment upon the lungs. Concurrent to this experience is increasing recognition of the ubiquitous role of intra-abdominal hypertension (IAH) in critical illness, of the relationship between IAH and intra-abdominal volume or thus the compliance of the abdominal wall, and of the potential difference in the abdominal influences between the extrapulmonary and pulmonary forms of acute respiratory distress syndrome. The present paper reviews reported data concerning intra-abdominal pressure (IAP) in association with the use of PV to explore the potential influence of IAH. While early authors stressed the importance of gravitationally unloading the abdominal cavity to unencumber the lung bases, this admonition has not been consistently acknowledged when PV has been utilized. Basic data required to understand the role of IAP/IAH in the physiology of PV have generally not been collected and/or reported. No randomized controlled trials or meta-analyses considered IAH in design or outcome. While the act of proning itself has a variable reported effect on IAP, abundant clinical and laboratory data confirm that the thoracoabdominal cavities are intimately linked and that IAH is consistently transmitted across the diaphragm--although the transmission ratio is variable and is possibly related to the compliance of the abdominal wall. Any proning-related intervention that secondarily influences IAP/IAH is likely to greatly influence respiratory mechanics and outcomes. Further study of the role of IAP/IAH in the physiology and outcomes of PV in hypoxemic respiratory failure is thus required. Theories relating inter-relations between prone positioning and the

  6. 34 CFR 30.24 - What opportunity does the debtor receive to obtain a review of the existence or amount of a debt?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What opportunity does the debtor receive to obtain a review of the existence or amount of a debt? 30.24 Section 30.24 Education Office of the Secretary... Procedures § 30.24 What opportunity does the debtor receive to obtain a review of the existence or amount...

  7. Capsule review of the DOE research and development and field facilities

    SciTech Connect

    1980-09-01

    A description is given of the roles of DOE's headquarters, field offices, major multiprogram laboratories, Energy Technology and Mining Technology Centers, and other government-owned, contractor-operated facilities, which are located in all regions of the US. Descriptions of DOE facilities are given for multiprogram laboratories (12); program-dedicated facilities (biomedical and environmental facilities-12, fossil energy facilities-7, fusion energy facility-1, nuclear development facilities-3, physical research facilities-4, safeguards facility-1, and solar facilities-2); and Production, Testing, and Fabrication Facilities (nuclear materials production facilities-5, weapon testing and fabrication complex-8). Three appendices list DOE field and project offices; DOE field facilities by state or territory, names, addresses, and telephone numbers; DOE R and D field facilities by type, contractor names, and names of directors. (MCW)

  8. 14 CFR 1216.308 - Preparation of draft statements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... environmental impact statement in the manner provided in 40 CFR part 1502 of the CEQ Regulations and shall submit the draft statement and any attachments to the Associate Administrator for Management for NASA review prior to any formal review outside NASA. This submission shall be accompanied by a list of...

  9. 14 CFR 1216.308 - Preparation of draft statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... environmental impact statement in the manner provided in 40 CFR part 1502 of the CEQ Regulations and shall submit the draft statement and any attachments to the Associate Administrator for Management for NASA review prior to any formal review outside NASA. This submission shall be accompanied by a list of...

  10. 14 CFR 1216.308 - Preparation of draft statements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... environmental impact statement in the manner provided in 40 CFR part 1502 of the CEQ Regulations and shall submit the draft statement and any attachments to the Associate Administrator for Management for NASA review prior to any formal review outside NASA. This submission shall be accompanied by a list of...

  11. Comparative review of US Department of Energy CERCLA Federal Facility Agreements

    SciTech Connect

    Siegel, M.R.; Gephart, R.E.; Hendrickson, P.L.; Keller, J.F.; Waller, W.K.

    1989-12-01

    The purpose of this report is to present a comparison of the three FFAs executed by DOE and EPA. The report is intended to serve as a convenient reference guide for those responsible for drafting or reviewing future FFAs being considered by DOE. In addition, this report can provide the framework for the future analysis completed FFAs and aid in the assessment of the relative merits of approaches and provisions used for different sites. 13 tabs.

  12. 77 FR 43609 - Endangered and Threatened Wildlife and Plants; Incidental Take Permit Application; Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... association with implementation of a regional habitat conservation plan (HCP) in the San Luis Valley, Colorado... HCP and draft environmental assessment for review and comment by the public and Federal, Tribal, State... sanluisvalleyhcp@fws.gov . You also may send comments by facsimile to (970) 245-6933. The draft HCP and EA...

  13. 76 FR 28789 - Draft Alert Entitled “Preventing Occupational Respiratory Disease From Dampness in Office...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... HUMAN SERVICES Centers for Disease Control and Prevention Draft Alert Entitled ``Preventing Occupational... Disease Control and Prevention (CDC), announces the availability of a draft Alert entitled ``Preventing... found at: http://nioshdev.cdc.gov/niosh/docket/review/docket238/default.html . The purpose of this...

  14. A Multidisciplinary Research Team Approach to Computer-Aided Drafting (CAD) System Selection. Final Report.

    ERIC Educational Resources Information Center

    Franken, Ken; And Others

    A multidisciplinary research team was assembled to review existing computer-aided drafting (CAD) systems for the purpose of enabling staff in the Design Drafting Department at Linn Technical College (Missouri) to select the best system out of the many CAD systems in existence. During the initial stage of the evaluation project, researchers…

  15. 78 FR 26616 - Draft NOAA Five Year Research and Development Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-07

    ... NOAA Five Year Research and Development Plan AGENCY: National Oceanic and Atmospheric Administration (NOAA), Department of Commerce (DOC). ACTION: Draft NOAA Five Year Research and Development Plan for Public Review. SUMMARY: NOAA's draft Five Year Research and Development Plan is available for...

  16. 77 FR 36001 - Draft Report Assessing Rural Water Activities and Related Programs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... Bureau of Reclamation Draft Report Assessing Rural Water Activities and Related Programs AGENCY: Bureau of Reclamation, Interior. ACTION: Notice of availability. SUMMARY: The draft Rural Water Assessment Report reviews the status of the Bureau of Reclamation's rural potable water projects and its plan...

  17. Performance testing of extremity dosimeters against a draft standard

    SciTech Connect

    Harty, R.; Reece, W.D.; Hooker, C.D.; McDonald, J.C.

    1990-09-01

    The assurance of worker radiation safety is directly related to the performance of personnel dosimetry. The US Department of Energy (DOE) has long recognized this critical relationship and has addressed this issue by instituting the DOE Laboratory Accreditation Program (DOELAP) which strives to improve the quality of personnel dosimetry through performance testing, dosimetry calibration, intercomparisons, evaluations and accreditations. One area of personnel dosimetry that has not been specifically addressed by DOELAP is extremity dosimeter testing. This task was directed at assessing the problems of implementing extremity dosimeter performance testing. A series of performance tests were made based on a draft standard written by the Health Physics Society Standards Committee (HPSSC) using extremity dosimeters currently in use at DOE and DOE contractor facilities. The results of this study indicate the need to incorporate performance testing of extremity dosimetry systems into DOELAP. Based on the results of this study, recommendations are made for improvements to the draft standard. 20 refs., 6 figs., 3 tabs.

  18. Review and Hypothesis: Does Graves' Disease Develop in Non-Human Great Apes?

    PubMed Central

    Alpi, Kristine; Rapoport, Basil

    2011-01-01

    Background Graves' disease, caused by stimulatory thyrotropin receptor (TSHR) autoantibodies, has not been observed in animals. In contrast, Hashimoto's thyroiditis develops in chickens, rats, mice, dogs, and marmosets. Attempts to induce an immune response in mice to the luteinizing-hormone receptor suggested that autoantigen glycosylation was one parameter involved in breaking self-tolerance. Over evolution, TSHR glycosylation increased from three asparagine-linked-glycans (N-glycans) in fish to six N-glycans in humans and great apes. All other placental mammals lack one N-glycan in the shed TSHR A-subunit, the primary Graves' disease autoantigen. We hypothesized that (a) lesser TSHR A-subunit glycosylation reduces immunogenicity, accounting for the absence of Graves' disease in most placental mammals; (b) due to human-like A-subunit glycosylation, Graves' disease might arise in great apes. Here, we review and analyze the literature on this subject and report the results of a survey of veterinarians at primate centers and zoos in North America. Summary Previous experimental data from induced TSHR antibodies in mice support a role for A-subunit glycosylation in breaking self-tolerance. An extensive search of the great-ape literature revealed five reports of noncongenital thyroid dysfunction, four with hypothyroidism and one with hyperthyroidism. The latter was a gorilla who was treated with anti-thyroid drugs but is now deceased. Neither serum nor thyroid tissue from this gorilla were available for analysis. The survey of veterinarians revealed that none of the 979 chimpanzees in primate research centers had a diagnosis of noncongenital thyroid dysfunction and among ∼1100 great apes (gorillas, orangutans, and chimpanzees) in U.S. zoos, only three were hypothyroid, and none were hyperthyroid. Conclusions Graves' disease appears to be either very rare or does not occur in great apes based on the literature and a survey of veterinarians. Although the available data

  19. DOE EERE Standard Operating Procedure Peer Review Best Practice and Procedures

    SciTech Connect

    2009-01-18

    Objective review and advice from peers - peer review - provides managers, staff, and researchers with a powerful and effective tool for enhancing the management, relevance, effectiveness, and productivity of all of the EERE research, development

  20. Nitrogenase: A Draft Mechanism

    PubMed Central

    Hoffman, Brian M.; Lukoyanov, Dmitriy; Dean, Dennis R.; Seefeldt, Lance C.

    2013-01-01

    consideration of previous studies, imply a pathway in which (i) N2 binds at E4 with liberation of H2, (ii) N2 is promptly reduced to N2H2, (iii) the two N’s are hydrogenated alternately to form hydrazine-bound FeMo-co, and (iv) two NH3 are liberated in two further steps of reduction. This proposal identifies nitrogenase as following a ‘Prompt-Alternating (P-A)’ reaction pathway, and unifies the catalytic pathway with the LT kinetic framework. However, it does not incorporate one of the most puzzling aspects of nitrogenase catalysis: obligatory generation of H2 upon N2 binding that apparently ‘wastes’ two reducing equivalents and thus 25% of the total energy supplied by the hydrolysis of ATP. The finding that E4 stores its four accumulated reducing equivalents as two bridging hydrides, considered in the context of the organometallic chemistries of hydrides and dihydrogen, leads us to propose an answer to this puzzle. Namely, that H2 release upon N2 binding involves reductive elimination of two hydrides to yield N2 bound to doubly reduced Fe. Coupled delivery of the two available electrons and two activating protons yields cofactor-bound diazene, in keeping with the P-A scheme. This keystone completes a draft mechanism for nitrogenase that organizes the vast body of data upon which it is formulated, and is intended to serve as a basis for future experiments. PMID:23289741

  1. Persuasive System Design Does Matter: A Systematic Review of Adherence to Web-Based Interventions

    PubMed Central

    Kok, Robin N; Ossebaard, Hans C; Van Gemert-Pijnen, Julia EWC

    2012-01-01

    Background Although web-based interventions for promoting health and health-related behavior can be effective, poor adherence is a common issue that needs to be addressed. Technology as a means to communicate the content in web-based interventions has been neglected in research. Indeed, technology is often seen as a black-box, a mere tool that has no effect or value and serves only as a vehicle to deliver intervention content. In this paper we examine technology from a holistic perspective. We see it as a vital and inseparable aspect of web-based interventions to help explain and understand adherence. Objective This study aims to review the literature on web-based health interventions to investigate whether intervention characteristics and persuasive design affect adherence to a web-based intervention. Methods We conducted a systematic review of studies into web-based health interventions. Per intervention, intervention characteristics, persuasive technology elements and adherence were coded. We performed a multiple regression analysis to investigate whether these variables could predict adherence. Results We included 101 articles on 83 interventions. The typical web-based intervention is meant to be used once a week, is modular in set-up, is updated once a week, lasts for 10 weeks, includes interaction with the system and a counselor and peers on the web, includes some persuasive technology elements, and about 50% of the participants adhere to the intervention. Regarding persuasive technology, we see that primary task support elements are most commonly employed (mean 2.9 out of a possible 7.0). Dialogue support and social support are less commonly employed (mean 1.5 and 1.2 out of a possible 7.0, respectively). When comparing the interventions of the different health care areas, we find significant differences in intended usage (p = .004), setup (p < .001), updates (p < .001), frequency of interaction with a counselor (p < .001), the system (p = .003) and peers (p

  2. EPA's Review of DOE's Inventory Tracking for TRU Wastes at Waste Control Specialists

    EPA Pesticide Factsheets

    On April 9, 2014, EPA's Waste Isolation Pilot Plant (WIPP) waste characterization team visited Waste Control Specialists (WCS) to determine whether DOE was meeting EPA's waste inventory tracking requirements at 40 CFR 194.24(c)(4).

  3. How Does Student Peer Review Influence Perceptions, Engagement and Academic Outcomes? A Case Study

    ERIC Educational Resources Information Center

    Mulder, Raoul; Baik, Chi; Naylor, Ryan; Pearce, Jon

    2014-01-01

    Involving students in peer review has many pedagogical benefits, but few studies have explicitly investigated relationships between the content of peer reviews, student perceptions and assessment outcomes. We conducted a case study of peer review within a third-year undergraduate subject at a research-intensive Australian university, in which we…

  4. An Interim Report on NASA's Draft Space Technology Roadmaps

    NASA Technical Reports Server (NTRS)

    2011-01-01

    NASA has developed a set of 14 draft roadmaps to guide the development of space technologies under the leadership of the NASA Office of the Chief Technologist (OCT). Each of these roadmaps focuses on a particular technology area (TA). The roadmaps are intended to foster the development of advanced technologies and concepts that address NASA's needs and contribute to other aerospace and national needs. OCT requested that the National Research Council conduct a study to review the draft roadmaps, gather and assess relevant community input, and make recommendations and suggest priorities to inform NASA's decisions as it finalizes its roadmaps. The statement of task states that "based on the results of the community input and its own deliberations, the steering committee will prepare a brief interim report that addresses high-level issues associated with the roadmaps, such as the advisability of modifying the number or technical focus of the draft NASA roadmaps." This interim report, which does not include formal recommendations, addresses that one element of the study charge. NASA requested this interim report so that it would have the opportunity to make an early start in modifying the draft roadmaps based on feedback from the panels and steering committee. The final report will address all other tasks in the statement of task. In particular, the final report will include a prioritization of technologies, will describe in detail the prioritization process and criteria, and will include specific recommendations on a variety of topics, including many of the topics mentioned in this interim report. In developing both this interim report and the final report to come, the steering committee draws on the work of six study panels organized by technical area, loosely following the organization of the 14 roadmaps, as follows: A Panel 1: Propulsion and Power TA01 Launch Propulsion Systems TA02 In-Space Propulsion Technologies TA03 Space Power and Energy Storage Systems TA13

  5. Site characterization and hazard assessment criteria for natural phenomena hazards at DOE sites

    SciTech Connect

    Chen, J.C.; Lu, S.C.; Ueng, T.S.; Boissonnade, A.C.

    1993-09-01

    This paper briefly summarizes requirements for site characterization and hazard assessment of Natural Phenomena Hazards for compliance with DOE Order 5480.28. The site characterization criteria for NPH evaluation are provided in a draft DOE-STD-1022-XX and the assessment criteria of natural phenomena hazards are provided in draft DOE-STD-1023-XX.

  6. Drafting--Basic, Drafting--Intermediate: 9255.01.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    The course has no prerequisites, offers instruction in basic drafting room techniques and procedures, and also covers job opportunities and industrial methods in engineering. The student is introduced to and asked to perform fundamental drafting problems with working drawings, using multiview and auxiliary views and sections. The course also…

  7. A review of the safety features of 6M packagings for DOE programs

    SciTech Connect

    Not Available

    1988-12-01

    This report, prepared by a US Department of Energy (DOE) Task Force and organized for clarity into two-page modules, argues that the US Department of Transportation (DOT) Specification-6M packagings (hereafter referred to as 6M packaging, or simply 6M) merit continued DOE use and, if necessary, DOE certification. This report is designed to address the specific requirements of a Safety Analysis Report for Packaging (SARP). While not a SARP, this report constitutes a compilation of all available documentation on 6M packagings. The authors individually, and the Task Force collectively, believe their investigation provides justification for the continued use of 6M packagings because they meet criteria for quality assurance and for safety under normal and accident conditions as defined by the US Nuclear Regulatory Commission (NRC) regulations. This report may be used by DOE managers to assist in deliberations on future requirements for 6M packagings as they are required to support DOE programs. For the purpose of ready evaluation, this report includes categorical topics found in Nuclear Regulatory Guide 7.9, the topical guideline for SARPs. The format, however, will (it is hoped) pleasantly surprise customary reader expectations. For, while maintaining categorical headings and subheadings found in SARPs as a skeleton, the Task Force chose to adopt the document design principles developed by Hughes Aircraft in the 1960s, ''Sequential Thematic Organization of Publications'' (STOP). 37 figs.

  8. 78 FR 33090 - Re-Opening of the Public Comment Period for the Draft Uranium Leasing Program Programmatic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Re-Opening of the Public Comment Period for the Draft Uranium Leasing Program Programmatic Environmental...: The U.S. Department of Energy (DOE) is re-opening the public comment period for the Draft...

  9. 75 FR 4801 - Notice of Availability of the Draft Long-Term Management and Storage of Elemental Mercury...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... of Availability of the Draft Long-Term Management and Storage of Elemental Mercury Environmental... Management and Storage of Elemental Mercury Environmental Impact Statement (DOE/EIS-0423D, ``Draft Mercury... effects of storing a projected total of up to 10,000 metric tons (11,000 tons) of elemental mercury....

  10. Computer Aided Drafting. Instructor's Guide.

    ERIC Educational Resources Information Center

    Henry, Michael A.

    This guide is intended for use in introducing students to the operation and applications of computer-aided drafting (CAD) systems. The following topics are covered in the individual lessons: understanding CAD (CAD versus traditional manual drafting and care of software and hardware); using the components of a CAD system (primary and other input…

  11. Proceedings of the DOE chemical/hydrogen energy contractor review systems

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Chemical/hydrogen energy system contracts were reviewed. The review served as an effective means to (1) give all contracts an insight into the background and objectives of thirty-nine hydrogen-related tasks, (2) show the status of the studies or technical effort, (3) relate any problems that had impeded the progress, and (4) state projected solutions for resolving the identified problems.

  12. 77 FR 3770 - Draft Research Report: Investigation of Ground Water Contamination near Pavillion, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... peer review, will convene an independent panel of experts for peer review of this draft research report. Public comments submitted during the public comment period will be made available to the peer review panel for consideration in their review. An external peer review meeting will take place following...

  13. Review and Identification of DOE Laboratory Technologies for Countermine/Unexploded Ordnance Detection

    SciTech Connect

    Smith, C.M.

    2002-04-03

    Several Department of Energy (DOE) laboratories have worked and/or are working on technologies that are applicable to the detection of landmines and/or unexploded ordnance. This report is a compilation of technical summaries for many of these technologies. For additional information on any technology, appropriate points of contact are provided for each technology.

  14. Consultation draft: Site characterization plan overview, Deaf Smith County Site, Texas: Nuclear Waste Policy Act (Section 113)

    SciTech Connect

    Not Available

    1988-01-01

    The Department of Energy (DOE) is preparing a site characterization plan for the candidate site in Deaf Smith County, Texas. The DOE has provided, for information and review, a consultation draft of the plan to the State of Texas and the US Nuclear Regulatory Commission. The site characterization plan is a lengthy document that describes in considerable detail the program that will be conducted to characterize the geologic, hydrologic, and other conditions relevant to the suitability of the site for a repository. The overview presented here consists of brief summaries of important topics covered in the consultation draft of the site characterization plan; it is not a substitute for the site characterization plan. The arrangement of the overview is similar to that of the plan itself, with brief descriptions of the repository system - the site, the repository, and the waste package - preceding the discussion of the characterization program to be carried out at the Deaf Smith County site. It is intended primarily for the management staff of organizations involved in the DOE's repository program or other persons who might wish to understand the general scope of the site-characterization program, the activities to be conducted, and the facilities to be constructed rather than the technical details of site characterization. 15 figs., 1 tab.

  15. Does integrated care reduce hospital activity for patients with chronic diseases? An umbrella review of systematic reviews

    PubMed Central

    Damery, Sarah; Flanagan, Sarah; Combes, Gill

    2016-01-01

    Objective To summarise the evidence regarding the effectiveness of integrated care interventions in reducing hospital activity. Design Umbrella review of systematic reviews and meta-analyses. Setting Interventions must have delivered care crossing the boundary between at least two health and/or social care settings. Participants Adult patients with one or more chronic diseases. Data sources MEDLINE, Embase, ASSIA, PsycINFO, HMIC, CINAHL, Cochrane Library (HTA database, DARE, Cochrane Database of Systematic Reviews), EPPI-Centre, TRIP, HEED, manual screening of references. Outcome measures Any measure of hospital admission or readmission, length of stay (LoS), accident and emergency use, healthcare costs. Results 50 reviews were included. Interventions focused on case management (n=8), chronic care model (CCM) (n=9), discharge management (n=15), complex interventions (n=3), multidisciplinary teams (MDT) (n=10) and self-management (n=5). 29 reviews reported statistically significant improvements in at least one outcome. 11/21 reviews reported significantly reduced emergency admissions (15–50%); 11/24 showed significant reductions in all-cause (10–30%) or condition-specific (15–50%) readmissions; 9/16 reported LoS reductions of 1–7 days and 4/9 showed significantly lower A&E use (30–40%). 10/25 reviews reported significant cost reductions but provided little robust evidence. Effective interventions included discharge management with postdischarge support, MDT care with teams that include condition-specific expertise, specialist nurses and/or pharmacists and self-management as an adjunct to broader interventions. Interventions were most effective when targeting single conditions such as heart failure, and when care was provided in patients’ homes. Conclusions Although all outcomes showed some significant reductions, and a number of potentially effective interventions were found, interventions rarely demonstrated unequivocally positive effects. Despite the

  16. Does the engagement of clinicians and organisations in research improve healthcare performance: a three-stage review

    PubMed Central

    Boaz, Annette; Hanney, Stephen; Jones, Teresa; Soper, Bryony

    2015-01-01

    Objective There is a widely held assumption that engagement by clinicians and healthcare organisations in research improves healthcare performance at various levels, but little direct empirical evidence has previously been collated. The objective of this study was to address the question: Does research engagement (by clinicians and organisations) improve healthcare performance? Methods An hourglass-shaped review was developed, consisting of three stages: (1) a planning and mapping stage; (2) a focused review concentrating on the core question of whether or not research engagement improves healthcare performance; and (3) a wider (but less systematic) review of papers identified during the two earlier stages, focusing on mechanisms. Results Of the 33 papers included in the focused review, 28 identified improvements in health services performance. Seven out of these papers reported some improvement in health outcomes, with others reporting improved processes of care. The wider review demonstrated that mechanisms such as collaborative and action research can encourage some progress along the pathway from research engagement towards improved healthcare performance. Organisations that have deliberately integrated the research function into organisational structures demonstrate how research engagement can, among other factors, contribute to improved healthcare performance. Conclusions Current evidence suggests that there is an association between the engagement of individuals and healthcare organisations in research and improvements in healthcare performance. The mechanisms through which research engagement might improve healthcare performance overlap and rarely act in isolation, and their effectiveness often depends on the context in which they operate. PMID:26656023

  17. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on...

  18. 75 FR 81643 - Hydropower Resource Assessment at Existing Reclamation Facilities-Draft Report

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... Bureau of Reclamation Hydropower Resource Assessment at Existing Reclamation Facilities--Draft Report AGENCIES: Bureau of Reclamation, Interior. ACTION: Reopening of comment period for review of the Hydropower... committed to increasing the generation of environmentally sustainable, affordable hydropower for...

  19. 77 FR 48995 - Draft National Toxicology Program (NTP) Monograph on Developmental Effects and Pregnancy Outcomes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... during Pregnancy, prepared by the Office of Health Assessment and Translation (OHAT), DNTP. Cancer... and/or in combination therapy as reported in the peer-reviewed literature. The draft monograph...

  20. A DOE manual: DOE methods for evaluating environmental and waste management samples

    SciTech Connect

    Goheen, S.C.; Fadeff, S.K.; Sklarew, D.S.; McCulloch, M.; Mong, G.M.; Riley, R.G.; Thomas, B.L.

    1994-08-01

    DOE Methods for Evaluating Environmental and Waste Management Samples (DOE Methods) is a guidance/methods document supporting environmental restoration (ER) and waste management (WM) (collectively referred to as EM) sampling and analysis activities at US Department of Energy (DOE) sites. DOE Methods is intended to supplement existing guidance documents (e.g., the US Environmental Protection Agency`s Test Methods for Evaluating Solid Waste, SW-846), which apply to low-level or non-radioactive samples, and the complexities of waste and environmental samples encountered at DOE sites. The document contains quality assurance (QA), quality control (QC), safety, sampling, organic analysis, inorganic analysis, and radio-analytical guidance as well as sampling and analytical methods. It is updated every six months (April and October) with additional methods. As of April 1994, DOE methods contained 3 sampling and 39 analytical methods. It is anticipated that between 10 and 20 new methods will be added in October 1994. All methods are either peer reviewed and contain performance data, or are included as draft methods.

  1. Proceedings of the 1994 DOE/NREL Hydrogen Program Review, April 18--21, 1994, Livermore, California

    SciTech Connect

    Not Available

    1994-07-01

    The US Department of Energy has conducted programs of research and development in hydrogen and related technologies since 1975. The current program, conducted in accordance with the DOE Hydrogen Program Plan FY 1993--FY 1997 published in June 1992, establishes program priorities and guidance for allocating funding. The core program, currently under the Office of Energy Management, supports projects in the areas of hydrogen production, storage, and systems research. At an annual program review, each research project is evaluated by a panel of technical experts for technical quality, progress, and programmatic benefit. This Proceedings of the April 1994 Hydrogen Program Review compiles all research projects supported by the Hydrogen Program during FY 1994. For those people interested in the status of hydrogen technologies, we hope that the Proceedings will serve as a useful technical reference. Individual reports are processed separately.

  2. 76 FR 50490 - Draft Comprehensive Conservation Plan and Draft Environmental Impact Statement, Arctic National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... Fish and Wildlife Service Draft Comprehensive Conservation Plan and Draft Environmental Impact... conservation plan (CCP) and draft environmental impact statement (DEIS) for the Arctic National Wildlife Refuge... Refuge System, consistent with sound principles of fish and wildlife management, conservation,...

  3. 46 CFR 78.50-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place... of the draft marks, due to raked stem or cut—away skeg, the datum line from which the draft shal...

  4. 46 CFR 78.50-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place... of the draft marks, due to raked stem or cut—away skeg, the datum line from which the draft shal...

  5. 46 CFR 78.50-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place... of the draft marks, due to raked stem or cut—away skeg, the datum line from which the draft shal...

  6. 46 CFR 167.55-1 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or... aft to the location of the draft marks, due to a raked stem or cut away skeg, the draft must...

  7. Draft Test Guideline: Tadpole/Sediment Subchronic Toxicity Test

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  8. Draft Test Guideline: Generic Freshwater Microcosm Test, Laboratory

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  9. Draft Test Guideline: Oyster Acute Toxicity Test (Shell Deposition)

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  10. Draft Test Guideline: Site-Specific Aquatic Microcosm Test, Laboratory

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  11. Draft Test Guideline: Fish Acute Toxicity Test, Freshwater And Marine

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  12. Draft Test Guideline: Bivalve Acute Toxicity Test (Embryo Larval)

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  13. Draft Test Guideline: Whole Sediment Acute Toxicity Invertebrates, Marine

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  14. Draft Test Guideline: Aquatic Invetebrate Acute Toxicity, Test, Freshwater Daphnids

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  15. Draft Test Guideline: Fish Acute Toxicity Mitigated By Humic Acid

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  16. Draft Test Guideline: Special Considerations for Conducting Aquatic Laboratory Studies

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  17. Draft Test Guideline: Field Testing For Aquatic Organisms

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  18. Draft Test Guideline: Fish Early-Life Stage Toxicity Test

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  19. Draft Test Guideline: Whole Sediment Acute Toxicity Invertebrates, Freshwater

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  20. 76 FR 55391 - Notice of Postponement of Release of Draft NTP Monograph on Potential Developmental Effects of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ... Effects of Cancer Chemotherapy During Pregnancy and Panel Meeting To Peer Review Draft Monograph AGENCY... Developmental Effects of Cancer Chemotherapy during Pregnancy and the peer review panel meeting. Release of...