Sample records for dol generic solution

  1. 77 FR 70825 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; DOL Generic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-27

    ... for OMB Review; Comment Request; DOL Generic Solution for Customer Satisfaction Surveys and Conference... request (ICR) titled, ``DOL Generic Solution for Customer Satisfaction Surveys and Conference Evaluations...). SUPPLEMENTARY INFORMATION: The DOL periodically conducts customer satisfaction surveys and conference...

  2. 77 FR 55506 - Office of the Assistant Secretary for Administration and Management; Agency Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... Customer Satisfaction Surveys and Conference Evaluations ACTION: Notice. SUMMARY: The Department of Labor... periodically conducts customer satisfaction surveys and conference evaluations that help assess Departmental... of Collection: DOL Generic Solution for Customer Satisfaction Surveys and Conference Evaluations. OMB...

  3. 77 FR 55505 - Office of the Assistant Secretary for Administration and Management; Agency Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... Management. Type of Review: Extension without change of a currently approved collection. Title of Collection... DEPARTMENT OF LABOR Office of the Assistant Secretary for Administration and Management; Agency Information Collection Activities; Extension Without Change; Comment Request; DOL Generic Solution for...

  4. 76 FR 22920 - Agency Information Collection Activities: Proposed Collection; Comment Request; DOL Generic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-25

    ... requirements or power calculations that justify the proposed sample size, the expected response rate, methods... Collection; Comment Request; DOL Generic Clearance for the Collection of Qualitative Feedback on Agency... of Qualitative Feedback on Agency Service Delivery'' to the Office of Management and Budget (OMB) for...

  5. Calcium Solubility In Zeolite Synthetic-Apatite Mixtures

    NASA Technical Reports Server (NTRS)

    Beiersdorfer, R.; Ming, D. W.

    1999-01-01

    Life support systems at a lunar or martian outpost will require the ability to produce food growing in 1) treated lunar or martian regolith; 2) a synthetic soil, or 3) some combination of both. Zeoponic soil, composed of NH4 (-) and K-exchanged clinoptilolite (Cp) and synthetic apatite (Ap), can provide slow-release fertilization via dissolution and ion-exchange. Equilibrium studies indicate that KNH4, P, and Mg are available to plants at sufficient levels, however, Ca is deficient. Ca availability can be increased by adding a second Ca-bearing mineral: calcite (Cal); dolomite (Dol); or wollastonite (Wol). Additions of Cal, Dol, and Wol systematically change the concentrations of Ca and P in solution. Cal has the greatest effect, Dol the least, and Wol is intermediate.

  6. Recycling of dolichyl monophosphate to the cytoplasmic leaflet of the endoplasmic reticulum after the cleavage of dolichyl pyrophosphate on the lumenal monolayer.

    PubMed

    Rush, Jeffrey S; Gao, Ningguo; Lehrman, Mark A; Waechter, Charles J

    2008-02-15

    During protein N-glycosylation, dolichyl pyrophosphate (Dol-P-P) is discharged in the lumenal monolayer of the endoplasmic reticulum (ER). Dol-P-P is then cleaved to Dol-P by Dol-P-P phosphatase (DPPase). Studies with the yeast mutant cwh8Delta, lacking DPPase activity, indicate that recycling of Dol-P produced by DPPase contributes significantly to the pool of Dol-P utilized for lipid intermediate biosynthesis on the cytoplasmic leaflet. Whether Dol-P formed in the lumen diffuses directly back to the cytoplasmic leaflet or is first dephosphorylated to dolichol has not been determined. Incubation of sealed ER vesicles from calf brain with acetyl-Asn-Tyr-Thr-NH(2), an N-glycosylatable peptide, to generate Dol-P-P in the lumenal monolayer produced corresponding increases in the rates of Man-P-Dol, Glc-P-Dol, and GlcNAc-P-P-Dol synthesis in the absence of CTP. No changes in dolichol kinase activity were observed. When streptolysin-O permeabilized CHO cells were incubated with an acceptor peptide, N-glycopeptide synthesis, requiring multiple cycles of the dolichol pathway, occurred in the absence of CTP. The results obtained with sealed microsomes and CHO cells indicate that Dol-P, formed from Dol-P-P, returns to the cytoplasmic leaflet where it can be reutilized for lipid intermediate biosynthesis, and dolichol kinase is not required for recycling. It is possible that the flip-flopping of the carrier lipid is mediated by a flippase, which would provide a mechanism for the recycling of Dol-P derived from Man-P-Dol-mediated reactions in N-, O-, and C-mannosylation of proteins, GPI anchor assembly, and the three Glc-P-Dol-mediated reactions in Glc(3)Man(9)GlcNAc(2)-P-P-Dol (DLO) biosynthesis.

  7. Calcium Solubility and Cation Exchange Properties in Zeoponic Soil

    NASA Technical Reports Server (NTRS)

    Beiersdorfer, Raymond E.

    1999-01-01

    An important aspect of a regenerative life support system at a Lunar or Martian outpost is the ability to produce food. Essential plant nutrients, as well as a solid support substrate, can be provided by: (1) treated Lunar or Martian regolith; (2) a synthetic soil or (3) some combination of both. A synthetic soil composed of ammonium- and potassium-saturated chinoptlolite (a zeolite mineral) and apatite, can provide slow-release fertilization of plants via dissolution and ion-exchange reactions. Previous equilibrium studies (Beiersdorfer, 1997) on mixtures of synthetic hydroxyapatite and saturated-clinoptilolite indicate that the concentrations of macro-nutrients such as ammonium, phosphorous, potassium, magnesium, and calcium are a function of the ratio of chinoptilolite to apatite in the sample and to the ratio of potassium to ammonium on the exchange sites in the clinoptilolite. Potassium, ammonium, phosphorous, and magnesium are available to plants at sufficient levels. However, calcium is deficient, due to the high degree of calcium adsorption by the clinoptilolite. Based on a series of batch-equilibration experiments, this calcium deficiency can be reduced by (1) treating the clinoptilolite with CaNO3 or (2) adding a second Ca-bearing mineral (calcite, dolomite or wollastonite) to the soil. Treating the Cp with CaNO3 results in increased Ca in solution, decreased P in solution and decreased NH4 in solution. Concentrations of K were not effected by the CaNO3 treatment. Additions of Cal, Dol and Wol changed the concentrations of Ca and P in solution in a systematic fashion. Cal has the greatest effect, Dol the least and Wol is intermediate. The changes are consistent with changes expected for a common ion effect with Ca. Higher concentrations of Ca in solution with added Cal, Dol or Wol do not result in changes in K or NH4 concentrations.

  8. Ovarian control of nectar collection in the honey bee (Apis mellifera).

    PubMed

    Siegel, Adam J; Freedman, Colin; Page, Robert E

    2012-01-01

    Honey bees are a model system for the study of division of labor. Worker bees demonstrate a foraging division of labor (DOL) by biasing collection towards carbohydrates (nectar) or protein (pollen). The Reproductive ground-plan hypothesis of Amdam et al. proposes that foraging DOL is regulated by the networks that controlled foraging behavior during the reproductive life cycle of honey bee ancestors. Here we test a proposed mechanism through which the ovary of the facultatively sterile worker impacts foraging bias. The proposed mechanism suggests that the ovary has a regulatory effect on sucrose sensitivity, and sucrose sensitivity impacts nectar loading. We tested this mechanism by measuring worker ovary size (ovariole number), sucrose sensitivity, and sucrose solution load size collected from a rate-controlled artificial feeder. We found a significant interaction between ovariole number and sucrose sensitivity on sucrose solution load size when using low concentration nectar. This supports our proposed mechanism. As nectar and pollen loading are not independent, a mechanism impacting nectar load size would also impact pollen load size.

  9. 29 CFR 2.33 - Responsibilities of DOL, DOL social service providers and State and local governments...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... beneficiary on the basis of religion or religious belief. This requirement does not preclude DOL, DOL social... of Labor GENERAL REGULATIONS Equal Treatment in Department of Labor Programs for Religious Organizations; Protection of Religious Liberty of Department of Labor Social Service Providers and Beneficiaries...

  10. 29 CFR 2.33 - Responsibilities of DOL, DOL social service providers and State and local governments...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... beneficiary on the basis of religion or religious belief. This requirement does not preclude DOL, DOL social... of Labor GENERAL REGULATIONS Equal Treatment in Department of Labor Programs for Religious Organizations; Protection of Religious Liberty of Department of Labor Social Service Providers and Beneficiaries...

  11. 29 CFR 2.33 - Responsibilities of DOL, DOL social service providers and State and local governments...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... beneficiary on the basis of religion or religious belief. This requirement does not preclude DOL, DOL social... of Labor GENERAL REGULATIONS Equal Treatment in Department of Labor Programs for Religious Organizations; Protection of Religious Liberty of Department of Labor Social Service Providers and Beneficiaries...

  12. 29 CFR 2.33 - Responsibilities of DOL, DOL social service providers and State and local governments...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... beneficiary on the basis of religion or religious belief. This requirement does not preclude DOL, DOL social... of Labor GENERAL REGULATIONS Equal Treatment in Department of Labor Programs for Religious Organizations; Protection of Religious Liberty of Department of Labor Social Service Providers and Beneficiaries...

  13. 29 CFR 2.33 - Responsibilities of DOL, DOL social service providers and State and local governments...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... beneficiary on the basis of religion or religious belief. This requirement does not preclude DOL, DOL social... religion in a manner consistent with the Establishment Clause of the First Amendment to the Constitution... their views and to exercise their right to religious freedom. Additionally, subject to reasonable and...

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Su, Liang; Ferrandon, Magali; Barton, John L.

    The identification and development of conductive electrolytes with high concentrations of redox active species is key to realizing energy-dense nonaqueous flow batteries. Herein, we explore the use of ether solvents (1,3-dioxolane (DOL), 1,2-dimethoxyethane (DME), diethylene glycol dimethyl ether (DEGDME), and tetraethylene glycol dimethyl ether (TEGDME)) as the basis for redox electrolytes containing a lithium ion supporting salt (LiBF4 or LiTFSI) and 2,5-di-tert-butyl-1,4-bis(2-methoxyethoxy)benzene (DBBB) as an active material. An automated high-throughput platform is employed to screen various electrolyte compositions by measuring solution conductivity and solute solubility as a function of solvent and salt type, component concentration, and temperature. Subsequently, the electrochemicalmore » and transport properties of select redox electrolytes are characterized by cyclic voltammetry using glassy carbon disk electrodes and by linear sweep voltammetry using carbon fiber ultramicroelectrodes. In general, improvements in electrolyte conductivity and solute solubility are observed with ether-based formulations as compared to previously reported propylene carbonate (PC)-based formulations. In particular, the addition of DOL to a DME-based electrolyte increases the conductivity and decreases the temperature for solubilization at high LiTFSI and DBBB concentrations. The redox behavior of DBBB remains consistent across the range of concentrations tested while the diffusion coefficient scales with changes in solution viscosity.« less

  15. Sequence identity and antigenic cross-reactivity of white face hornet venom allergen, also a hyaluronidase, with other proteins.

    PubMed

    Lu, G; Kochoumian, L; King, T P

    1995-03-03

    White face hornet (Dolichovespula maculata) venom has three known protein allergens which induce IgE response in susceptible people. They are antigen 5, phospholipase A1, and hyaluronidase, also known as Dol m 5, 1, and 2, respectively. We have cloned Dol m 2, a protein of 331 residues. When expressed in bacteria, a mixture of recombinant Dol m 2 and its fragments was obtained. The fragments were apparently generated by proteolysis of a Met-Met bond at residue 122, as they were not observed for a Dol m 2 mutant with a Leu-Met bond. Dol m 2 has 56% sequence identity with the honey bee venom allergen hyaluronidase and 27% identity with PH-20, a human sperm protein with hyaluronidase activity. A common feature of hornet venom allergens is their sequence identity with other proteins in our environment. We showed previously the sequence identity of Dol m 5 with a plant protein and a mammalian testis protein and of Dol m 1 with mammalian lipases. In BALB/c mice, Dol m 2 and bee hyaluronidase showed cross-reactivity at both antibody and T cell levels. These findings are relevant to some patients' multiple sensitivity to hornet and bee stings.

  16. 48 CFR 2901.105-3 - Copies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Office Web Page, http://www.gpo.gov/. Requests should reference the DOLAR as chapter 29 of title 48. The... information on DOL may be obtained on the Internet at www.dol.gov. Other DOL procurement policy documents...

  17. 48 CFR 2901.105-3 - Copies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Office Web Page, http://www.gpo.gov/. Requests should reference the DOLAR as chapter 29 of title 48. The... information on DOL may be obtained on the Internet at www.dol.gov. Other DOL procurement policy documents...

  18. 48 CFR 2901.105-3 - Copies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Office Web Page, http://www.gpo.gov/. Requests should reference the DOLAR as chapter 29 of title 48. The... information on DOL may be obtained on the Internet at www.dol.gov. Other DOL procurement policy documents...

  19. 48 CFR 2901.105-3 - Copies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Office Web Page, http://www.gpo.gov/. Requests should reference the DOLAR as chapter 29 of title 48. The... information on DOL may be obtained on the Internet at www.dol.gov. Other DOL procurement policy documents...

  20. 48 CFR 2901.105-3 - Copies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Office Web Page, http://www.gpo.gov/. Requests should reference the DOLAR as chapter 29 of title 48. The... information on DOL may be obtained on the Internet at www.dol.gov. Other DOL procurement policy documents...

  1. Ovarian Control of Nectar Collection in the Honey Bee (Apis mellifera)

    PubMed Central

    Siegel, Adam J.; Freedman, Colin; Page, Robert E.

    2012-01-01

    Honey bees are a model system for the study of division of labor. Worker bees demonstrate a foraging division of labor (DOL) by biasing collection towards carbohydrates (nectar) or protein (pollen). The Reproductive ground-plan hypothesis of Amdam et al. proposes that foraging DOL is regulated by the networks that controlled foraging behavior during the reproductive life cycle of honey bee ancestors. Here we test a proposed mechanism through which the ovary of the facultatively sterile worker impacts foraging bias. The proposed mechanism suggests that the ovary has a regulatory effect on sucrose sensitivity, and sucrose sensitivity impacts nectar loading. We tested this mechanism by measuring worker ovary size (ovariole number), sucrose sensitivity, and sucrose solution load size collected from a rate-controlled artificial feeder. We found a significant interaction between ovariole number and sucrose sensitivity on sucrose solution load size when using low concentration nectar. This supports our proposed mechanism. As nectar and pollen loading are not independent, a mechanism impacting nectar load size would also impact pollen load size. PMID:22558073

  2. 77 FR 74880 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    .... SUMMARY: The Department of Labor (DOL) is submitting the Employment and Training Administration (ETA... this request to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA... submission of responses. Agency: DOL-ETA. Title of Collection: Reemployment Demonstration Grants and Projects...

  3. 78 FR 31581 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Registered...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ...: The Department of Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored... of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and... electronic submission of responses. Agency: DOL-ETA. Title of Collection: Registered Apprenticeship College...

  4. 77 FR 55227 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Veterans...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-07

    ... Department of Labor (DOL) is submitting the Employment and Training Administration (ETA sponsored information... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room... electronic submission of responses. Agency: DOL-ETA. Title of Collection: Veterans Retraining Assistance...

  5. 78 FR 52214 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Derricks...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information... Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room 10235, 725...., permitting electronic submission of responses. Agency: DOL-OSHA. Title of Collection: Derricks Standard. OMB...

  6. The Value of a Community College Education: A Preliminary Report.

    ERIC Educational Resources Information Center

    Coperthwaite, Corby A.

    This document summarizes findings from an analysis of participants in Connecticut community college occupational programs conducted by the Department of Labor (DOL). The community colleges provided the DOL with files containing the social security numbers of all occupational program participants for an academic year. DOL then matched these files…

  7. 29 CFR 14.3 - DOL Classification Review Committee.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true DOL Classification Review Committee. 14.3 Section 14.3 Labor... Classification Review Committee. A DOL Classification Review Committee is hereby established. (a) Composition of... under the Freedom of Information Act, 5 U.S.C. 552, when a proposed denial is based on classification...

  8. 78 FR 25476 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Benzene...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Department of Labor (DOL) will submit the Occupational Safety and Health Administration (OSHA) sponsored... Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room 10235, 725... submission of responses. Agency: DOL-OSHA. Title of Collection: Benzene Standard. OMB Control Number: 1218...

  9. 77 FR 36296 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Cadmium in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ... Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room... submission of responses. Agency: DOL-OSHA. Title of Collection: Cadmium in Construction Standard. OMB Control...

  10. 77 FR 45689 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; The 1,2...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room..., e.g., permitting electronic submission of responses. Agency: DOL-OSHA. Title of Collection: The 1,2...

  11. 77 FR 36295 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Cadmium in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ... Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room... submission of responses. Agency: DOL-OSHA. Title of Collection: Cadmium in General Industry Standard. OMB...

  12. 76 FR 6634 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... the Frances Perkins Building ACTION: Notice. SUMMARY: The Department of Labor (DOL) hereby announces... by Non-DOL Agencies in the Frances Perkins Building,'' to the Office of Management and Budget (OMB... Application for Use of Public Space by Non-DOL Agencies in the Frances Perkins Building, Form DL1-6062B, that...

  13. 20 CFR 666.130 - Under what conditions may a State or DOL request revisions to the State negotiated levels of...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... request revisions to the State negotiated levels of performance? 666.130 Section 666.130 Employees... a State or DOL request revisions to the State negotiated levels of performance? (a) The DOL guidelines describe when and under what circumstances a Governor may request revisions to negotiated levels...

  14. 20 CFR 666.130 - Under what conditions may a State or DOL request revisions to the State negotiated levels of...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... request revisions to the State negotiated levels of performance? 666.130 Section 666.130 Employees... a State or DOL request revisions to the State negotiated levels of performance? (a) The DOL guidelines describe when and under what circumstances a Governor may request revisions to negotiated levels...

  15. Right ventricular involution: What can we learn from nature's model of compensated hypertrophy?

    PubMed

    Bowen, Megan E; Liu, Xiaoqing; Sundwall, Peter M; Drakos, Stavros G; Li, Dean Y; Selzman, Craig H; McKellar, Stephen H

    2018-05-01

    Right ventricular (RV) failure (RVF) is a vexing problem facing patients with various disease processes and carries a high mortality. RVF is a poorly understood phenomenon with limited treatment options. In mammalian fetal circulation, the right ventricle is the systemic ventricle. In neonates, however, the left ventricle assumes that role and gradually thickens compared with the right ventricle. This process, known as right ventricular involution (RVI), is poorly understood. We sought to define the time course and identify mechanisms involved in RVI. Wild-type mice were bred and sacrificed on day of life (DOL) 1, 4, 8, 16, and 30 to evaluate left ventricular (LV) and RV wall thickness and apoptosis. A terminal deoxynucleotidyl transferase nick-end labeling assay and RNA sequencing were performed to measure changes during RVI. Morphometric analysis demonstrated the changes in RV and LV wall thickness occurring between DOL 1 and DOL 16 (RV:LV, 0.53:0.44; P = .03). In addition, apoptosis was most active early, with the highest percentage of apoptotic cells on DOL 1 (1.0%) and a significant decrease by DOL 30 (0.23%) (P = .02). Similarly, expression of the proapoptotic genes BCL2l11 and Pawr were increased at DOL 1, and the antiapoptotic genes Nol3 and Naip2 were significantly increased at DOL 30. RVI is a misnomer, but significant changes occur early (by DOL 16) in neonatal mouse hearts. Apoptosis plays a role in RVI, but whether manipulation of apoptotic pathways can prevent or reverse RVI is unknown and warrants further investigation. Copyright © 2017 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

  16. Experimental determination of the solubility product of dolomite at 50-253 °C

    NASA Astrophysics Data System (ADS)

    Bénézeth, Pascale; Berninger, Ulf-Niklas; Bovet, Nicolas; Schott, Jacques; Oelkers, Eric H.

    2018-03-01

    The 'dolomite problem', the scarcity of present-day dolomite formation near the Earth's surface, has attracted much attention over the past century. Solving this problem requires having reliable data on the stability and kinetics of formation of this mineral. Toward this goal, the solubility of natural dolomite (CaMg(CO3)2) has been measured from 50 to 253 °C in 0.1 mol/kg NaCl solutions using a hydrogen electrode concentration cell (HECC). The obtained apparent solubility products (Kapp-sp-dol), for the reaction: CaMg(CO3)2 = Ca2+ + Mg2+ + 2CO32-, were extrapolated to infinite dilution to generate the solubility product constants for this reaction (Ksp°-dol). The derived equilibrium constants were fit and can be accurately described by log10Ksp°-dol = a + b/T (K) + cT (K) where a = 17.502, b = -4220.119 and c = -0.0689. This equation and its first and second derivatives with respect to T were used together with corresponding aqueous species properties to calculate the revised standard state thermodynamic properties of dolomite at 25 °C and 1 bar, yielding a Gibbs energy of formation (Δf G298.15∘) equal to -2160.9 ± 2 kJ/mol, (log10Ksp°-dol = -17.19 ± 0.3); an enthalpy of formation (Δf H298.15∘) of -2323.1 ± 2 kJ/mol, an entropy (S298.15∘) of 156.9 ± 2 J/mol/K and heat capacity (Cp298.15∘) of 154.2 ± 2 J/mol/K (uncertainties are 3σ). The dolomite solubility product derived in this study is nearly identical to that computed using SUPCRT92 (Johnson et al., 1992) at 200 °C, but about one order of magnitude higher at 50 and 25 °C, suggesting that dolomite may be somewhat less stable than previously assumed at ambient temperatures.

  17. Implications of a new case law on the Deprivation of Liberty Safeguards.

    PubMed

    Shah, Ajit

    2010-10-01

    The Deprivation of Liberty Safeguards (DOLS), introduced into the Mental Capacity Act 2005 (MCA), were implemented in April 2009. Recent case law established several principles: the Mental Health Act (MHA) has primacy over the MCA and it is not appropriate for professionals to pick and choose which Act to use; the eligibility assessors for DOLS need to consider whether a hospital would detain the patient under the MHA. The eligibility assessors for DOLS need to apply a 'but for' test, whereby consideration would need to be given to the need for detention in hospital if it were not for the physical illness, and if the only reason for detention in hospital was the need for treatment of the physical disorder then detention under DOLS would be appropriate. This judgement clarifies that individuals with mental disorders who only require treatment in hospital for physical disorders should be detained under DOLS. The implications of this judgement are discussed in this paper.

  18. Examining extrinsic factors that influence product acceptance: a review.

    PubMed

    Li, X E; Jervis, S M; Drake, M A

    2015-05-01

    Drivers of liking (DOL) studies are useful for product development to formulate acceptable products; however, DOL alone are insufficient for understanding why a product is purchased and repurchased, which is ultimately the indication of a successful product. Ultimately sensory attributes drive product success (that is, repeat and continued purchase). However, ignoring the importance of extrinsic factors may neglect the vital product attributes responsible for the initial purchase, which may in turn, affect repeat purchase. The perception of sensory attributes assessed by DOL is mitigated by external perceptions of quality. If the sensory attributes do not deliver based upon the quality cues, the product will not be acceptable. Four key extrinsic factors that affect DOL are the perceived satiety, brand and labeling, price, and the emotional impact to decision making. In order to more thoroughly understand what the DOL for a product is, these 4 product cues should be considered in conjunction with sensory attribute perception to gain a holistic understanding of product acceptance. © 2015 Institute of Food Technologists®

  19. Purification and characterization of a polyisoprenyl phosphate phosphatase from pig brain. Possible dual specificity.

    PubMed

    Frank, D W; Waechter, C J

    1998-05-08

    Microsomal fractions from pig and calf brain catalyze the enzymatic dephosphorylation of endogenous and exogenous dolichyl monophosphate (Dol-P) (Sumbilla, C. A., and Waechter, C. J. (1985) Methods Enzymol. 111, 471-482). The Dol-P phosphatase (EC 3.1.3.51) has been solubilized by extracting pig brain microsomes with the nonionic detergent Nonidet P-40 and purified approximately 1,107-fold by a combination of anion exchange chromatography, polyethylene glycol fractionation, dye-ligand chromatography, and wheat germ agglutinin affinity chromatography. Treatment of the enzyme with neuraminidase prevented binding to wheat germ agglutinin-Sepharose, indicating the presence of one or more N-acetylneuraminyl residues per molecule of enzyme. When the highly purified polyisoprenyl phosphate phosphatase was analyzed by SDS-polyacrylamide gel electrophoresis, a major 33-kDa polypeptide was observed. Enzymatic dephosphorylation of Dol-P by the purified phosphatase was 1) optimal at pH 7; 2) potently inhibited by F-, orthovanadate, and Zn2+ > Co2+ > Mn2+ but unaffected by Mg2+; 3) exhibited an approximate Km for C95-Dol-P of 45 microM; and 4) was sensitive to N-ethylmaleimide, phenylglyoxal, and diethylpyrocarbonate. The pig brain phosphatase did not dephosphorylate glucose 6-phosphate, mannose 6-phosphate, 5'-AMP, or p-nitrophenylphosphate, but it dephosphorylated dioleoyl-phosphatidic acid at initial rates similar to those determined for Dol-P. Based on the virtually identical sensitivity of Dol-P and phosphatidic acid dephosphorylation by the highly purified enzyme to N-ethylmaleimide, F-, phenylglyoxal, and diethylpyrocarbonate, both substrates appear to be hydrolyzed by a single enzyme with an apparent dual specificity. This is the first report of the purification of a neutral Dol-P phosphatase from mammalian tissues. Although the enzyme is Mg2+-independent and capable of dephosphorylating Dol-P and PA, several enzymological properties distinguish this lipid phosphomonoesterase from PAP2.

  20. Department of Labor. Challenges in Ensuring Workforce Development and Worker Protection. Testimony before the Subcommittee on Human Resources, Committee on Government Reform and Oversight, House of Representatives.

    ERIC Educational Resources Information Center

    Joyner, Carlotta C.

    In Fiscal Year 1997, the U.S. Department of Labor (DOL) has an estimated budget of $34.4 billion and is authorized 16,614 full-time-equivalent staff-years. DOL's many programs fall into two major categories: enhancing workers' skills through job training and ensuring worker protection. The DOL's work force development mission is being challenged…

  1. Modeling of Dolichol Mass Spectra Isotopic Envelopes as a Tool to Monitor Isoprenoid Biosynthesis.

    PubMed

    Jozwiak, Adam; Lipko, Agata; Kania, Magdalena; Danikiewicz, Witold; Surmacz, Liliana; Witek, Agnieszka; Wojcik, Jacek; Zdanowski, Konrad; Pączkowski, Cezary; Chojnacki, Tadeusz; Poznanski, Jaroslaw; Swiezewska, Ewa

    2017-06-01

    The cooperation of the mevalonate (MVA) and methylerythritol phosphate (MEP) pathways, operating in parallel in plants to generate isoprenoid precursors, has been studied extensively. Elucidation of the isoprenoid metabolic pathways is indispensable for the rational design of plant and microbial systems for the production of industrially valuable terpenoids. Here, we describe a new method, based on numerical modeling of mass spectra of metabolically labeled dolichols (Dols), designed to quantitatively follow the cooperation of MVA and MEP reprogrammed upon osmotic stress (sorbitol treatment) in Arabidopsis ( Arabidopsis thaliana ). The contribution of the MEP pathway increased significantly (reaching 100%) exclusively for the dominating Dols, while for long-chain Dols, the relative input of the MEP and MVA pathways remained unchanged, suggesting divergent sites of synthesis for dominating and long-chain Dols. The analysis of numerically modeled Dol mass spectra is a novel method to follow modulation of the concomitant activity of isoprenoid-generating pathways in plant cells; additionally, it suggests an exchange of isoprenoid intermediates between plastids and peroxisomes. © 2017 American Society of Plant Biologists. All Rights Reserved.

  2. Modeling of Dolichol Mass Spectra Isotopic Envelopes as a Tool to Monitor Isoprenoid Biosynthesis1[OPEN

    PubMed Central

    Kania, Magdalena; Witek, Agnieszka; Wojcik, Jacek; Zdanowski, Konrad; Pączkowski, Cezary; Chojnacki, Tadeusz; Poznanski, Jaroslaw

    2017-01-01

    The cooperation of the mevalonate (MVA) and methylerythritol phosphate (MEP) pathways, operating in parallel in plants to generate isoprenoid precursors, has been studied extensively. Elucidation of the isoprenoid metabolic pathways is indispensable for the rational design of plant and microbial systems for the production of industrially valuable terpenoids. Here, we describe a new method, based on numerical modeling of mass spectra of metabolically labeled dolichols (Dols), designed to quantitatively follow the cooperation of MVA and MEP reprogrammed upon osmotic stress (sorbitol treatment) in Arabidopsis (Arabidopsis thaliana). The contribution of the MEP pathway increased significantly (reaching 100%) exclusively for the dominating Dols, while for long-chain Dols, the relative input of the MEP and MVA pathways remained unchanged, suggesting divergent sites of synthesis for dominating and long-chain Dols. The analysis of numerically modeled Dol mass spectra is a novel method to follow modulation of the concomitant activity of isoprenoid-generating pathways in plant cells; additionally, it suggests an exchange of isoprenoid intermediates between plastids and peroxisomes. PMID:28385729

  3. SLS Trade Study 0058: Day of Launch (DOL) Wind Biasing

    NASA Technical Reports Server (NTRS)

    Decker, Ryan K.; Duffin, Paul; Hill, Ashley; Beck, Roger; Dukeman, Greg

    2014-01-01

    SLS heritage hardware and legacy designs have shown load exceedances at several locations during Design Analysis Cycles (DAC): MPCV Z bending moments; ICPS Electro-Mechanical Actuator (EMA) loads; Core Stage loads just downstream of Booster forward interface. SLS Buffet Loads Mitigation Task Team (BLMTT) tasked to study issue. Identified low frequency buffet load responses are a function of the vehicle's total angle of attack (AlphaTotal). SLS DOL Wind Biasing Trade team to analyze DOL wind biasing methods to limit maximum AlphaTotal in the M0.8 - 2.0 altitude region for EM-1 and EM-2 missions through investigating: Trajectory design process; Wind wavelength filtering options; Launch availability; DOL process to achieve shorter processing/uplink timeline. Trade Team consisted of personnel supporting SLS, MPCV, GSDO programs.

  4. Crushed and Injected Buprenorphine Tablets: Characteristics of Princeps and Generic Solutions

    PubMed Central

    Bouquié, Régis; Wainstein, Laura; Pilet, Paul; Mussini, Jean-Marie; Deslandes, Guillaume; Clouet, Johann; Dailly, Eric; Jolliet, Pascale; Victorri-Vigneau, Caroline

    2014-01-01

    Self-injection of high-dose buprenorphine is responsible for well-described complications. In 2011, we have been alerted by unusual but serious cutaneous complication among injection buprenorphine users. A prospective data collection identified 30 cases of necrotic cutaneous lesions after injection of filtered buprenorphine solution, among which 25 cases occurred following injection of buprenorphine generics. The main goal of our study was to put forward particularities that could explain the cutaneous complications, by qualitatively and quantitatively confronting particles present in Subutex and generics solutions. We used the same protocol that injected-buprenorphine users: generic or subutex tablets were crushed in sterile water and filtered through 2 filters commonly used (cotton-pad and sterifilt). Solutions were analyzed by laser granulometry, flow cytometry and scanning electron microscopy. We have highlighted the wide variation of the quantity and the size of the particles present in solution between the two drugs after cotton-pad filtration. The proportion of particles <10 µm is systematically higher in the generic solutions than with Subutex. All of the insoluble particles found in generic solutions contain silica, whereas non- organic element was to be identified in the insoluble particles of Subutex. One skin biopsy obtained from one patient who developed a necrotic lesion after intravenous injection of filtrated solution of buprenorphine generic, shows non-organic elements. Identification of particles in situ enables us to confirm the presence of silica in the biopsy. Actually the monitoring of patient receiving generic of buprenorphine must be strengthened. PMID:25474108

  5. Does daily kangaroo care provide sustained pain and stress relief in preterm infants?

    PubMed

    Mitchell, A J; Yates, C C; Williams, D K; Chang, J Y; Hall, R Whit

    2013-01-01

    1. Determine whether stress in preterm infants, measured with salivary cortisol, decreases after five days of Kangaroo Care (KC) compared to five days of Standard Care (SC). 2. To determine whether kangaroo care provides sustainable pain relief beyond the period of skin-to-skin holding. Preterm infants (n = 38) born at 27-30 weeks gestational age were randomized to either the KC or the SC group and received the allocated intervention starting on day of life (DOL) five and continuing for five days. Salivary cortisol was collected on DOL five and again on DOL ten. Differences were analyzed using repeated measures ANOVA and t tests. Pain during nasal suctioning over five days was assessed using the Premature Infant Pain Profile (PIPP). 1. Adequate saliva samples for salivary cortisol were collected for 13 KC infants and 11 SC infants. There was no main effect of group (p = 0.49), but there was a significant main effect of age (DOL five versus DOL ten), with salivary cortisol levels decreasing in both groups (p = 0.02). 2. Pain scores for both groups (n = 38) indicted mild to moderate pain during suctioning, with no significant difference in pain scores between groups. 1. KC did not affect salivary cortisol levels in preterm neonates, but levels in both the KC and SC groups decreased over time from DOL five to ten. Salivary cortisol may vary with age of infant. 2. Infants experience pain during routine suctioning and may require pain management.

  6. 20 CFR 670.995 - What DOL equal opportunity and nondiscrimination regulations apply to Job Corps?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TRAINING ADMINISTRATION, DEPARTMENT OF LABOR THE JOB CORPS UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Administrative and Management Provisions § 670.995 What DOL equal opportunity and nondiscrimination regulations...

  7. Effect of fluid flux on the width of contact metamorphic aureoles: evidence from Silver Star, Montana

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Foote, M.V.; Frost, B.R.; Angevine, C.L.

    1985-01-01

    Contact metamorphism of Paleozoic carbonate-rich sediments by the Boulder Batholith near Silver Star, Montana has resulted in the formation of the following six metamorphic zones: (1) calcite (cc) - dolomite (dol) - quartz (q) - phlogopite (phl) +/- kspar (ksp); (b) cc - dol - tremolite (tr) - q - ksp; (c) cc - dol - tr - diopside (di) - phl; (d) cc - dol - di - forsterite (fo) - phl; (e) cc - dol - fo, and cc - di - fo; and (f) cc - fo - periclase +/- dol. The presence of periclase in themore » highest zone indicates that these rocks crystallized in the presence of a water-rich fluid. Calculations of reaction progress indicate that between zone e and zone f, 4.5 rock-volumes of water had to be introduced. Comparison of the aureole at Silver Star with other contact aureoles studied around the Boulder Batholith shows a distinct correlation between the width of the aureole and the inferred fluid flux. The Boulder and Marysville aureoles are internally buffered throughout and have a width (measured to the tremolite-in isograd) of up to 1.5 km, while the Black Butte aureole, which has largely external control of the fluid, has a width of approximately 80 meters. Silver Star, which is intermediate in behavior, has an aureole width of approximately 250 meters. The indicates that in environments of low fluid flux heat is transported largely by conduction, while in environments of low fluid flux most of the heat is transported upward by convective flow, resulting in correspondingly narrower aureoles.« less

  8. Characterization of dolichol and dolichyl phosphate phosphatase from soya beans (Glycine max).

    PubMed Central

    Ravi, K; Rip, J W; Carroll, K K

    1983-01-01

    A series of polyprenols, ranging in length from 15 to 22 isoprene units, has been isolated from soya beans (Glycine max) and purified by high-pressure liquid chromatography. N.m.r., i.r. and mass spectra of the compounds indicated that they are alpha-saturated polyprenols of the dolichol type. The amount present in dry seeds was about 9 mg/100 g, whereas dolichyl phosphate (Dol-P) was present only in trace amounts. Dol-P phosphatase activity was detected in the microsomal fraction of 5-day-old germinating soya-bean cotyledons. The Dol-P phosphatase activity was linear with respect to time and protein concentration and exhibited a broad pH optimum (pH 7-9). Triton X-100 was necessary for significant enzyme activity. Enzyme activity was slightly enhanced by EDTA, whereas dithiothreitol was without effect. An apparent Km of 5 microM was determined for Dol-P. Bivalent metal ions were not required for enzyme activity. A number of phosphorylated compounds tested as enzyme substrates (including a number of nucleoside phosphates, glucose 6-phosphate, sodium beta-glycerophosphate and Na4P2O7) did not compete with [1-3H]Dol-P as substrate. A number of phospholipids were also tested for their ability to act as Dol-P phosphatase substrates. At 1 mM concentration, phosphatidylcholine, phosphatidylethanolamine, phosphatidic acid and lysophosphatidic acid each inhibited enzymic activity. However, at 0.1 mM concentration, phosphatidylcholine and phosphatidylethanolamine were slightly stimulatory, whereas phosphatidic acid and lysophosphatidic acid were still inhibitory. Phosphatidic acid showed competitive inhibition. PMID:6311165

  9. Optical fiber-mediated photosynthesis for enhanced subsurface oxygen delivery.

    PubMed

    Lanzarini-Lopes, Mariana; Delgado, Anca G; Guo, Yuanming; Dahlen, Paul; Westerhoff, Paul

    2018-03-01

    Remediation of polluted groundwater often requires oxygen delivery into subsurface to sustain aerobic bacteria. Air sparging or injection of oxygen containing solutions (e.g., hydrogen peroxide) into the subsurface are common. In this study visible light was delivered into the subsurface using radially emitting optical fibers. Phototrophic organisms grew near the optical fiber in a saturated sand column. When applying light in on-off cycles, dissolved oxygen (DO) varied from super saturation levels of >15 mg DO/L in presence of light to under-saturation (<5 mg DO/L) in absence of light. Non-photosynthetic bacteria dominated at longer radial distances from the fiber, presumably supported by soluble microbial products produced by the photosynthetic microorganisms. The dissolved oxygen variations alter redox condition changes in response to light demonstrate the potential to biologically deliver oxygen into the subsurface and support a diverse microbial community. The ability to deliver oxygen and modulate redox conditions on diurnal cycles using solar light may provide a sustainable, long term strategy for increasing dissolved oxygen levels in subsurface environments and maintaining diverse biological communities. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. 20 CFR 670.994 - How does Job Corps resolve disputes between DOL and other Federal Agencies?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ADMINISTRATION, DEPARTMENT OF LABOR THE JOB CORPS UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Administrative and Management Provisions § 670.994 How does Job Corps resolve disputes between DOL and other Federal...

  11. 78 FR 25478 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Walking...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room... information technology, [[Page 25479

  12. 77 FR 38659 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... (DOL) will submit the Occupational Safety and Health Administration (OSHA) sponsored information... submission of responses. Agency: DOL-OSHA. Title of Collection: Occupational Safety and Health Administration... for OMB Review; Comment Request; Occupational Safety and Health Administration Strategic Partnership...

  13. 42 CFR 82.11 - For which claims under EEOICPA will NIOSH conduct a dose reconstruction?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... covered employee with cancer under DOL regulations at 20 CFR 30.210(b), subject to the limitation and... seeking compensation for a specified cancer, as determined by DOL under 20 CFR 30.210(a), do not require...

  14. 42 CFR 82.11 - For which claims under EEOICPA will NIOSH conduct a dose reconstruction?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... covered employee with cancer under DOL regulations at 20 CFR 30.210(b), subject to the limitation and... seeking compensation for a specified cancer, as determined by DOL under 20 CFR 30.210(a), do not require...

  15. 42 CFR 82.11 - For which claims under EEOICPA will NIOSH conduct a dose reconstruction?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... covered employee with cancer under DOL regulations at 20 CFR 30.210(b), subject to the limitation and... seeking compensation for a specified cancer, as determined by DOL under 20 CFR 30.210(a), do not require...

  16. 42 CFR 82.11 - For which claims under EEOICPA will NIOSH conduct a dose reconstruction?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... covered employee with cancer under DOL regulations at 20 CFR 30.210(b), subject to the limitation and... seeking compensation for a specified cancer, as determined by DOL under 20 CFR 30.210(a), do not require...

  17. 42 CFR 82.11 - For which claims under EEOICPA will NIOSH conduct a dose reconstruction?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... covered employee with cancer under DOL regulations at 20 CFR 30.210(b), subject to the limitation and... seeking compensation for a specified cancer, as determined by DOL under 20 CFR 30.210(a), do not require...

  18. Analysis and metabolic engineering of lipid-linked oligosaccharides in glycosylation-deficient CHO cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jones, Meredith B., E-mail: mbauman7@jhu.edu; Tomiya, Noboru, E-mail: ntomiya1@jhu.edu; Betenbaugh, Michael J., E-mail: beten@jhu.edu

    2010-04-23

    Glycosylation-deficient Chinese Hamster Ovary (CHO) cell lines can be used to expand our understanding of N-glycosylation pathways and to study Congenital Disorders of Glycosylation, diseases caused by defects in the synthesis of N-glycans. The mammalian N-glycosylation pathway involves the step-wise assembly of sugars onto a dolichol phosphate (P-Dol) carrier, forming a lipid-linked oligosaccharide (LLO), followed by the transfer of the completed oligosaccharide onto the protein of interest. In order to better understand how deficiencies in this pathway affect the availability of the completed LLO donor for use in N-glycosylation, we used a non-radioactive, HPLC-based assay to examine the intermediates inmore » the LLO synthesis pathway for CHO-K1 cells and for three different glycosylation-deficient CHO cell lines. B4-2-1 cells, which have a mutation in the dolichol phosphate-mannose synthase (DPM2) gene, accumulated LLO with the structure Man{sub 5}GlcNAc{sub 2}-P-P-Dol, while MI8-5 cells, which lack glucosyltransferase I (ALG6) activity, accumulated Man{sub 9}GlcNAc{sub 2}-P-P-Dol. CHO-K1 and MI5-4 cells both produced primarily the complete LLO, Glc{sub 3}Man{sub 9}GlcNAc{sub 2}-P-P-Dol, though the relative quantity was lower in MI5-4. MI5-4 cells have reduced hexokinase activity which could affect the availability of many of the substrates required for LLO synthesis and, consequently, impair production of the final LLO donor. Increasing hexokinase activity by overexpressing hexokinase II in MI5-4 caused a decrease in the relative quantities of the incomplete LLO intermediates from Man{sub 5}GlcNAc{sub 2}-PP-Dol through Glc{sub 1}Man{sub 9}GlcNAc{sub 2}-PP-Dol, and an increase in the relative quantity of the final LLO donor, Glc{sub 3}Man{sub 9}GlcNAc{sub 2}-P-P-Dol. This study suggests that metabolic engineering may be a useful strategy for improving LLO availability for use in N-glycosylation.« less

  19. 77 FR 23278 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Workforce...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... (ETA) sponsored information collection request (ICR) titled, ``Workforce Investment Streamlined... this request to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA... electronic submission of responses. Agency: DOL-ETA. Title of Collection: Workforce Investment Streamlined...

  20. 77 FR 71449 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Benefit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... (ETA) sponsored information collection request (ICR) titled, ``Benefit Accuracy Measurement Program... of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and... submission of responses. Agency: DOL-ETA. Title of Collection: Benefit Accuracy Measurement Program. OMB...

  1. 42 CFR 81.1 - Purpose and Authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... (a) The purpose of this regulation is to establish guidelines DOL will apply to adjudicate cancer claims for covered employees seeking compensation for cancer, other than as members of the Special Exposure Cohort seeking compensation for a specified cancer. To award a claim, DOL must first determine...

  2. 42 CFR 81.1 - Purpose and Authority.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... (a) The purpose of this regulation is to establish guidelines DOL will apply to adjudicate cancer claims for covered employees seeking compensation for cancer, other than as members of the Special Exposure Cohort seeking compensation for a specified cancer. To award a claim, DOL must first determine...

  3. 78 FR 17233 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Process...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    ... ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled, ``Process Safety Management of...., permitting electronic submission of responses. Agency: DOL-OSHA. Title of Collection: Process Safety...

  4. 78 FR 78385 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... pertaining to noise exposure-monitoring and audiometric testing. The Occupational Safety and Health Act... submission of responses. Agency: DOL-OSHA. Title of Collection: Occupational Noise Exposure Standard. OMB...

  5. 78 FR 7456 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Hexavalent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... submit the Occupational Safety and Health Administration (OSHA) sponsored information collection request... of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and..., e.g., permitting electronic submission of responses. Agency: DOL-OSHA. Title of Collection...

  6. 78 FR 19313 - Office of the Secretary

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... Department of Labor (DOL) will submit the Occupational Safety and Health Administration (OSHA) sponsored... request to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office... Standard at 29 CFR 1910.269 address safety procedures for the use of electrical protective equipment and...

  7. 76 FR 15224 - Reducing Regulatory Burden; Retrospective Review Under E.O. 13563

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... Department's Regulations Portal at http://www.dol.gov/regulations/regreview.htm . All comments will be.... The Department recognizes the knowledge of programs and their implementing regulations that exists... portal specifically designed to capture your input and suggestions, http://www.dol.gov/regulations...

  8. 29 CFR 2.30 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...; Protection of Religious Liberty of Department of Labor Social Service Providers and Beneficiaries § 2.30 Purpose. The purpose of the regulations in this subpart is to ensure that DOL-supported social service... to establish clearly the permissible uses to which DOL support for social service programs may be put...

  9. 29 CFR 2.30 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; Protection of Religious Liberty of Department of Labor Social Service Providers and Beneficiaries § 2.30 Purpose. The purpose of the regulations in this subpart is to ensure that DOL-supported social service... to establish clearly the permissible uses to which DOL support for social service programs may be put...

  10. 29 CFR 2.31 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... (b) The term social service program means a program that is administered or supported by the Federal... violence. (c) The term DOL means the U.S. Department of Labor. (d) The term DOL-supported social service... Organizations; Protection of Religious Liberty of Department of Labor Social Service Providers and Beneficiaries...

  11. 42 CFR 81.1 - Purpose and Authority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... (a) The purpose of this regulation is to establish guidelines DOL will apply to adjudicate cancer claims for covered employees seeking compensation for cancer, other than as members of the Special Exposure Cohort seeking compensation for a specified cancer. To award a claim, DOL must first determine...

  12. 42 CFR 81.1 - Purpose and Authority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... (a) The purpose of this regulation is to establish guidelines DOL will apply to adjudicate cancer claims for covered employees seeking compensation for cancer, other than as members of the Special Exposure Cohort seeking compensation for a specified cancer. To award a claim, DOL must first determine...

  13. 42 CFR 81.1 - Purpose and Authority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... (a) The purpose of this regulation is to establish guidelines DOL will apply to adjudicate cancer claims for covered employees seeking compensation for cancer, other than as members of the Special Exposure Cohort seeking compensation for a specified cancer. To award a claim, DOL must first determine...

  14. Development of a Climatology of Vertically Complete Wind Profiles from Doppler Radar Wind Profiler Systems

    NASA Technical Reports Server (NTRS)

    Barbre, Robert E., Jr.

    2015-01-01

    This paper describes in detail the QC and splicing methodology for KSC's 50- and 915-MHz DRWP measurements that generates an extensive archive of vertically complete profiles from 0.20-18.45 km. The concurrent POR from each archive extends from April 2000 to December 2009. MSFC NE applies separate but similar QC processes to each of the 50- and 915-MHz DRWP archives. DRWP literature and data examination provide the basis for developing and applying the automated and manual QC processes on both archives. Depending on the month, the QC'ed 50- and 915-MHz DRWP archives retain 52-65% and 16-30% of the possible data, respectively. The 50- and 915-MHz DRWP QC archives retain 84-91% and 85-95%, respectively, of all the available data provided that data exist in the non- QC'ed archives. Next, MSFC NE applies an algorithm to splice concurrent measurements from both DRWP sources. Last, MSFC NE generates a composite profile from the (up to) five available spliced profiles to effectively characterize boundary layer winds and to utilize all possible 915-MHz DRWP measurements at each timestamp. During a given month, roughly 23,000-32,000 complete profiles exist from 0.25-18.45 km from the composite profiles' archive, and approximately 5,000- 27,000 complete profiles exist from an archive utilizing an individual 915-MHz DRWP. One can extract a variety of profile combinations (pairs, triplets, etc.) from this sample for a given application. The sample of vertically complete DRWP wind measurements not only gives launch vehicle customers greater confidence in loads and trajectory assessments versus using balloon output, but also provides flexibility to simulate different DOL situations across applicable altitudes. In addition to increasing sample size and providing more flexibility for DOL simulations in the vehicle design phase, the spliced DRWP database provides any upcoming launch vehicle program with the capability to utilize DRWP profiles on DOL to compute vehicle steering commands, provided the program applies the procedures that this report describes to new DRWP data on DOL. Decker et al. (2015) details how SLS is proposing to use DRWP data and splicing techniques on DOL. Although automation could enhance the current DOL 50-MHz DRWP QC process and could streamline any future DOL 915-MHz DRWP QC and splicing process, the DOL community would still require manual intervention to ensure that the vehicle only uses valid profiles. If a program desires to use high spatial resolution profiles, then the algorithm could randomly add high-frequency components to the DRWP profiles. The spliced DRWP database provides lots of flexibility in how one performs DOL simulations, and the algorithms that this report provides will assist the aerospace and atmospheric communities that are interested in utilizing the DRWP.

  15. 29 CFR 96.51 - Purpose and scope of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Resolution § 96.51 Purpose and scope of subpart. This subpart prescribes standards for resolution of audit.... In cases where these standards conflict with statutes or other DOL regulations, the latter shall be controlling. The DOL Office of Inspector General (OIG) is available to assist agencies in the audit resolution...

  16. 78 FR 15740 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... of Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored information... Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room 10235, 725 17th...). SUPPLEMENTARY INFORMATION: Information collected on the Occupational Code Assignment Form (Form ETA-741) is...

  17. 77 FR 19036 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Labor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ..., 2012, the Department of Labor (DOL) will submit the Employment and Training Administration (ETA... Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room 10235... services through ETA 9002 reports and for Veterans' Employment and Training Services (VETS)- funded labor...

  18. 77 FR 58581 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Claims and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-21

    ... of Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored Information... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room.... 3507(a)(1)(D). SUPPLEMENTARY INFORMATION: Form ETA-5159 provides important program information on...

  19. 29 CFR 2.35 - Effect of DOL support on Title VII employment nondiscrimination requirements and on other...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... statutes. A religious organization's exemption from the Federal prohibition on employment discrimination on..., however, were established through Federal statutes containing independent statutory provisions requiring... appropriate DOL program official or with the Civil Rights Center, U.S. Department of Labor, 200 Constitution...

  20. 29 CFR 2.35 - Effect of DOL support on Title VII employment nondiscrimination requirements and on other...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... statutes. A religious organization's exemption from the Federal prohibition on employment discrimination on..., however, were established through Federal statutes containing independent statutory provisions requiring... appropriate DOL program official or with the Civil Rights Center, U.S. Department of Labor, 200 Constitution...

  1. 29 CFR 502.6 - Cooperation with DOL officials.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Cooperation with DOL officials. 502.6 Section 502.6 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED UNDER SECTION 218 OF THE...

  2. 29 CFR 14.10 - Mandatory review for declassification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Labor Office of the Secretary of Labor SECURITY REGULATIONS Review of Classified Information § 14.10... information originally classified by the DOL when it had such authority, i.e., before December 1, 1978... apply to information originated by other agencies and merely held in possession of the DOL. Requests for...

  3. 77 FR 65715 - Agency Information Collection Activities; Submissions for OMB Review; Comment Request; H-2A...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-30

    ... Prevailing Wage Determination ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting four... Certification Program, and Application for Prevailing Wage Determination. DATES: Submit comments on or before... DOL is submitting has been assigned ICR Reference Number 201210-1205-002, Application for Prevailing...

  4. 29 CFR 14.10 - Mandatory review for declassification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Labor Office of the Secretary of Labor SECURITY REGULATIONS Review of Classified Information § 14.10... information originally classified by the DOL when it had such authority, i.e., before December 1, 1978... apply to information originated by other agencies and merely held in possession of the DOL. Requests for...

  5. 29 CFR 35.17 - Age distinctions in DOL regulations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Age distinctions in DOL regulations. 35.17 Section 35.17 Labor Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF LABOR Standards for Determining Age...

  6. 29 CFR 35.17 - Age distinctions in DOL regulations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Age distinctions in DOL regulations. 35.17 Section 35.17 Labor Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF LABOR Standards for Determining Age...

  7. 29 CFR 35.17 - Age distinctions in DOL regulations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Age distinctions in DOL regulations. 35.17 Section 35.17 Labor Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF LABOR Standards for Determining Age...

  8. 29 CFR 35.17 - Age distinctions in DOL regulations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Age distinctions in DOL regulations. 35.17 Section 35.17 Labor Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF LABOR Standards for Determining Age...

  9. 29 CFR 35.17 - Age distinctions in DOL regulations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Age distinctions in DOL regulations. 35.17 Section 35.17 Labor Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF LABOR Standards for Determining Age...

  10. 77 FR 38832 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Marine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ...: On June 29, 2012, the Department of Labor (DOL) will submit the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled, ``Marine Terminals and Longshoring... request to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office...

  11. 77 FR 65414 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Lead in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room... occupational exposure to lead. Employers must monitor exposure to lead, provide medical surveillance, train...

  12. 77 FR 31878 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Blasting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    .... SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled, ``Blasting Operations and Use of... this request to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA...

  13. 77 FR 20435 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... for OMB Review; Comment Request; Occupational Safety and Health State Plans ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA... submission of responses. Agency: DOL-OSHA. Title of Collection: Occupational Safety and Health State Plans...

  14. 75 FR 68396 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Labor (DOL))-Match...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-05

    ... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA 2010-0052] Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Department of Labor (DOL))--Match Number 1003 AGENCY: Social Security... as shown above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection...

  15. 78 FR 67199 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Resource...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... of Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored information... Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room 10235, 725 17th...(a)(1)(D). SUPPLEMENTARY INFORMATION: This ICR seeks to extend PRA authorization for the ETA to...

  16. 77 FR 27485 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Experience...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-10

    ... Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored information... Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room 10235... INFORMATION: The Experience Rating Report (Form ETA-204) provides data to the ETA for the study of seasonality...

  17. 78 FR 71665 - Office of the Assistant Secretary for Administration and Management; Agency Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... DEPARTMENT OF LABOR Office of the Assistant Secretary for Administration and Management; Agency Information Collection Activities; Comment Request; Application for Use of Public Space by Non-DOL Agencies in..., ``Application for Use of Public Space by Non-DOL Agencies in the Frances Perkins Building.'' This comment...

  18. 48 CFR 522.805 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OFCCP regional office. A list of these offices can be found at http://www.dol.gov/esa/contacts/ofccp/ofcpkeyp.htm. (c) The EEO poster required by FAR 22.805(b) can be found at: http://www.dol.gov/esa/regs... contracting officer shall advise contractors to complete the Employer Information Report (EEO-1) at http://www...

  19. 29 CFR 95.52 - Financial reporting.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the status of funds for all nonconstruction projects or programs. DOL may, however, have the option of..., except that a final SF-269 or SF-269A shall be required at the completion of the project when the SF-270...) DOL shall determine the frequency of the Financial Status Report for each project or program...

  20. 76 FR 21041 - Information about the DOL Notification Process for Worker Abandonment, or Termination for Cause...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-14

    ... employment, or was terminated for cause before the end of the work contract period. DATES: This Notice is... employment fails to report for work at the regularly scheduled time for 5 consecutive work days without... DEPARTMENT OF LABOR Employment and Training Administration Information about the DOL Notification...

  1. 78 FR 69450 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Presence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ...: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA... the safety system, or a point-of-operation injury occurs. Occupational Safety and Health Act sections... or courier to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL- OSHA...

  2. 78 FR 71666 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Cranes and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ...: On November 29, 2013, the Department of Labor (DOL) will submit the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) revision titled, ``Cranes and Derricks in... to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL- OSHA, Office of...

  3. 77 FR 65415 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Lead in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room... associated with occupational exposure to lead. Employers must monitor exposure to lead, provide medical...

  4. 77 FR 17097 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; The 13...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ... of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... Institute for Occupational Safety and Health. This information collection is subject to the PRA. A Federal... Information and Regulatory Affairs, Attention: OMB Desk Officer for DOL-OSHA, Office of Management and Budget...

  5. 77 FR 56232 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Temporary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room... mandatory for covered employers to report to the local public health officer the name and address of any...

  6. 77 FR 24756 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Labor (DOL))-Match...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA 2011-0084] Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Department of Labor (DOL))--Match Number 1003 AGENCY: Social Security... above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988...

  7. 77 FR 24757 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Labor (DOL))-Match...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA 2011-0083] Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Department of Labor (DOL))--Match Number 1015 AGENCY: Social Security... regarding protections for such persons. The Privacy Act, as amended, regulates the use of computer matching...

  8. 29 CFR 95.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to make the property usable for the purpose for which it was acquired. Other charges, such as the... required work of the award have been completed by the recipient and DOL. (h) Commercial organization means... project or program costs not borne by DOL. (k) Date of completion means the date on which all work under...

  9. 75 FR 8402 - Child Labor, Forced Labor, and Forced or Indentured Child Labor in the Production of Goods in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ...). Based on DOL research and information submitted by the public, DOL issued an initial determination on... should be provided. If primary sources are utilized, such as research studies, interviews, direct observations, or other sources of quantitative or qualitative data, details on the research or data-gathering...

  10. 75 FR 58443 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Form 5500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ..., http://www.reginfo.gov/public/do/PRAMain or by contacting Michel Smyth by telephone at 202-693-4129 (this is not a toll-free number) or sending an email to DOL_PRA_PUBLIC@dol.gov . Submit comments about this request to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for the...

  11. Workforce Investment Act: Interim Report on Status of Spending and States' Available Funds. Report to Congressional Requesters.

    ERIC Educational Resources Information Center

    Nilsen, Sigurd R.

    A study assessed whether the Department of Labor's (DOL's) information on states' Workforce Investment Act of 1998 (WIA) spending was a true reflection of states' available funds. The most recent available spending data from DOL and the 50 states were analyzed. Interviews were conducted with state workforce officials in nine states, local…

  12. 76 FR 68015 - Federal Acquisition Regulation; Notification of Employee Rights Under the National Labor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ... Relations Act poster to subcontracts at all tiers that exceed $10,000. D. Comments on FAR Clause 52.222-40... contractors and subcontractors are required to use the DOL poster or have permission to create a company-specific poster, as long as the latter meets the DOL's size, form, and content requirements. Response: The...

  13. 20 CFR 410.591 - Eligibility for services and supplies under part C of title IV of the act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Payment of... DOL regulations covering the time period in which the miner must file with DOL for these benefits are published at 20 CFR part 725. (Sec. 411, Federal Coal Mine Health and Safety Act of 1969, as amended; 85...

  14. Tracking Antibody Distribution with Near-Infrared Fluorescent Dyes: Impact of Dye Structure and Degree of Labeling on Plasma Clearance.

    PubMed

    Cilliers, Cornelius; Nessler, Ian; Christodolu, Nikolas; Thurber, Greg M

    2017-05-01

    Monoclonal antibodies labeled with near-infrared (NIR) fluorophores have potential use in disease detection, intraoperative imaging, and pharmacokinetic characterization of therapeutic antibodies in both the preclinical and clinical setting. Recent work has shown conjugation of NIR fluorophores to antibodies can potentially alter antibody disposition at a sufficiently high degree of labeling (DoL); however, other reports show minimal impact after labeling with NIR fluorophores. In this work, we label two clinically approved antibodies, Herceptin (trastuzumab) and Avastin (bevacizumab), with NIR dyes IRDye 800CW (800CW) or Alexa Fluor 680 (AF680), at 1.2 and 0.3 dyes/antibody and examine the impact of fluorophore conjugation on antibody plasma clearance and tissue distribution. At 0.3 DoL, AF680 conjugates exhibited similar clearance to unlabeled antibody over 17 days while 800CW conjugates diverged after 4 days, suggesting AF680 is a more suitable choice for long-term pharmacokinetic studies. At the 1.2 DoL, 800CW conjugates cleared faster than unlabeled antibodies after several hours, in agreement with other published reports. The tissue biodistribution for bevacizumab-800CW and -AF680 conjugates agreed well with literature reported biodistributions using radiolabels. However, the greater tissue autofluorescence at 680 nm resulted in limited detection above background at low (∼2 mg/kg) doses and 0.3 DoL for AF680, indicating that 800CW is more appropriate for short-term biodistribution measurements and intraoperative imaging. Overall, our work shows a DoL of 0.3 or less for non-site-specifically labeled antibodies (with a Poisson distribution) is ideal for limiting the impact of NIR fluorophores on antibody pharmacokinetics.

  15. Early Caffeine Prophylaxis and Risk of Failure of Initial Continuous Positive Airway Pressure in Very Low Birth Weight Infants.

    PubMed

    Patel, Ravi M; Zimmerman, Kanecia; Carlton, David P; Clark, Reese; Benjamin, Daniel K; Smith, P Brian

    2017-11-01

    To test the hypothesis that early caffeine treatment on the day of birth, compared with later treatment in very low birth weight (VLBW, <1500 g) infants receiving continuous positive airway pressure (CPAP) therapy, is associated with a decreased risk of CPAP failure in the first week of life. Multicenter, observational cohort study in 366 US neonatal intensive care units. We evaluated inborn, VLBW infants discharged from 2000 to 2014, who received only CPAP therapy without surfactant treatment on day of life (DOL) 0, had a 5-minute Apgar ≥3, and received caffeine in the first week of life. We used multivariable conditional logistic regression to compare the risk of CPAP failure, defined as invasive mechanical ventilation or surfactant therapy on DOL 1-6, by timing of caffeine treatment as either early (initiation on DOL 0) or routine (initiation on DOL 1-6). We identified 11 133 infants; 4528 (41%) received early caffeine and 6605 (59%) received routine caffeine. Median gestational age was lower in the early caffeine group, 29 weeks (25th, 75th percentiles; 28, 30) vs the routine caffeine group, 30 weeks (29, 31); P < 0.001. The incidence of CPAP failure on DOL 1-6 was similar between the early and routine caffeine groups: 22% vs 21%; adjusted OR = 1.05 (95% CI: 0.93, 1.18). Early caffeine treatment on the day of birth was not associated with a decreased risk of CPAP failure in the first week of life for VLBW infants initially treated with CPAP. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Fermentation Enhancement of Methanogenic Archaea Consortia from an Illinois Basin Coalbed via DOL Emulsion Nutrition

    PubMed Central

    Xiao, Dong; Peng, Su-Ping; Wang, En-Yuan

    2015-01-01

    Microbially enhanced coalbed methane technology must be used to increase the methane content in mining and generate secondary biogenic gas. In this technology, the metabolic processes of methanogenic consortia are the basis for the production of biomethane from some of the organic compounds in coal. Thus, culture nutrition plays an important role in remediating the nutritional deficiency of a coal seam. To enhance the methane production rates for microorganism consortia, different types of nutrition solutions were examined in this study. Emulsion nutrition solutions containing a novel nutritional supplement, called dystrophy optional modification latex, increased the methane yield for methanogenic consortia. This new nutritional supplement can help methanogenic consortia form an enhanced anaerobic environment, optimize the microbial balance in the consortia, and improve the methane biosynthesis rate. PMID:25884952

  17. The Saccharomyces cerevisiae DPM1 gene encoding dolichol-phosphate-mannose synthase is able to complement a glycosylation-defective mammalian cell line.

    PubMed Central

    Beck, P J; Orlean, P; Albright, C; Robbins, P W; Gething, M J; Sambrook, J F

    1990-01-01

    The Saccharomyces cerevisiae DPM1 gene product, dolichol-phosphate-mannose (Dol-P-Man) synthase, is involved in the coupled processes of synthesis and membrane translocation of Dol-P-Man. Dol-P-Man is the lipid-linked sugar donor of the last four mannose residues that are added to the core oligosaccharide transferred to protein during N-linked glycosylation in the endoplasmic reticulum. We present evidence that the S. cerevisiae gene DPM1, when stably transfected into a mutant Chinese hamster ovary cell line, B4-2-1, is able to correct the glycosylation defect of the cells. Evidence for complementation includes (i) fluorescence-activated cell sorter analysis of differential lectin binding to cell surface glycoproteins, (ii) restoration of Dol-P-Man synthase enzymatic activity in crude cell lysates, (iii) isolation and high-performance liquid chromatography fractionation of the lipid-linked oligosaccharides synthesized in the transfected and control cell lines, and (iv) the restoration of endoglycosidase H sensitivity to the oligosaccharides transferred to a specific glycoprotein synthesized in the DPM1 CHO transfectants. Indirect immunofluorescence with a primary antibody directed against the DPM1 protein shows a reticular staining pattern of protein localization in transfected hamster and monkey cell lines. Images PMID:2201896

  18. The U.S. Department of Labor's Tractor and Machinery Certification Program: management styles and perceptions held by community stakeholders and instructors.

    PubMed

    Jepsen, S D

    2012-07-01

    A mixed-mode, descriptive study was conducted on the U.S. Department of Labor's (DOL) Tractor and Machinery Certification Program. Legislated by the Fair Labors Standards Act, the Hazardous Occupations Order in Agriculture (HOOA) was enacted in 1968 as a public policy measure to reduce the number of injuries to youth on farms. An educational exemption allows youth 14 and 15 years of age to work for hire after they successfully complete a training program. In the 40+ years since the legislation went into effect prescribing such training exemptions, deficiencies and variations have occurred in the quality of the educational program and the system by which agencies certify young people. To gain a better understanding of the DOL Tractor and Machinery Certification program, community stakeholders were asked to identify management practices, curriculum resources, and perceptions of the DOL program. The study design used qualitative data from 49 agricultural representatives participating in regional focus groups and quantitative data from 330 community instructors responding to an electronic-formatted questionnaire (representing a 70.7% response rate) in an effort to answer the question: "What is the current status of the DOL Tractor and Machinery Certification program in the United States?" The findings revealed that 55.2% of the instructors taught a qualifying DOL program. Of these, the certification was administered through an Extension or 4-H program (68.7%), an agricultural education program (24.7%), or as a combination of Extension and agricultural education (6.0%). Course instructors believed the training was beneficial to students and had opportunity to attract more students than currently enrolled These instructors placed a higher value on standardized teaching materials than on standardized testing procedures; they also supported the need for additional teaching aids, which included hands-on activities, videotapes, student workbooks, and DVDs. Study participants did not believe the program should be offered in its entirety as a self-study program but suggested that portions of the training could be offered in that manner The local instructors identified four primary issues that would increase the effectiveness of the DOL Tractor and Machinery Certification program: community awareness, employer support, access to teaching resources, and enforcement of the legislation.

  19. Palliative care clinicians' knowledge of the law regarding the use of the Deprivation of Liberty Safeguards (DoLS).

    PubMed

    Barry, Caroline; Spathis, Anna; Treaddell, Sarah; Carding, Sally; Barclay, Stephen

    2017-04-24

    To examine palliative care clinicians' level of knowledge of the law regarding the use of the Deprivation of Liberty Safeguards (DoLS). Regional postal survey of palliative care clinicians working in hospices in the East of England, undertaken in April 2015. Clinicians' level of knowledge was assessed by their response to 7 factual questions. Data regarding self-reported levels of confidence in applying the Safeguards was collected, alongside information regarding the number of times they had used DoLS in practice. A free-text section invited additional comments from participants. There were 47 responses from 14 different organisations; a response rate of 68%. Respondents included consultants, specialty and associate specialists, registrars, nurses and social workers. Higher self-reported confidence and training in the use of DoLS was associated with higher factual knowledge. Consultants had the highest level of knowledge, training and experience. Doctors of other grades, nurses and social workers recorded less knowledge and experience and scored lower in the knowledge sections. The free-text comments revealed difficulty applying the Safeguards in practice, particularly among the consultant responses, based around several themes: insufficient guidance on how to use the Safeguards, process after death, uncertainty as to relevance to palliative care and delays in assessments. Clinicians working in palliative care have good levels of knowledge of the DoLS. Despite this concerns were raised, particularly by consultants; uncertainty as to when they should be used and the relevance of the Safeguards in clinical practice. Further guidance should be given to clinicians working in this specialty to ensure that clinical practice is both lawful and in the patients' best interests. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  20. Supporting Employers in the Reserve Operational Forces Era: Are Changes Needed to Reservists’ Employment Rights Legislation, Policies, or Programs?

    DTIC Science & Technology

    2013-01-01

    hostile work environment. Here, the root cause of the controversy was the lack of statutory USERRA Overview 25 language specifically protecting... language with that of similar antidiscrimination laws (Pub. L. 112-56). Such revision was recommended by DOL in a 2010 report to Congress (DOL, 2011...with more than 2,000 employees) revealed that, due to the small proportion of the employee base they constitute, canine handlers and motorcycle patrol

  1. Factors that affect the postnatal increase in superior mesenteric artery blood flow velocity in very low birth weight preterm infants.

    PubMed

    Havranek, Thomas; Miladinovic, Branko; Wadhawan, Rajan; Carver, Jane D

    2012-04-15

    To identify factors related to the postnatal increase in superior mesenteric artery blood flow velocity (SMA BFV). SMA BFV was measured in 35 infants (birth weight 1047±246 g) on day of life (DOL) 1, 3, 5, 7 10 and 14. Latent curve modeling (LCM) was used to measure the longitudinal change in BFV for each subject, and the correlation between changes in BFV and baseline values. Non-parametric correlations were calculated between BFV and variables previously reported to be related to SMA BFV. There was significant variability in SMA BFV on DOL 1, a significant increase from DOL 1-14, and significant variability in the postnatal increase. Infants with higher enteral feeding volumes had greater increases, while infants receiving positive pressure ventilation or hyperalimentation had lower increases. Several clinical factors affect the postnatal increase in SMA BFV. The use of LCM is useful in longitudinal studies of very low birth weight (VLBW) infants, who are clinically and demographically heterogeneous.

  2. Adolescent occupational fatalities in North Carolina (1990-2008): an investigation of child labor and OSHA violations and enforcement.

    PubMed

    Rauscher, Kimberly; Runyan, Carol

    2012-01-01

    This study investigated adolescent worker fatalities involving violations of the child labor laws and/or Occupational Safety and Health Administration (OSHA) standards, as well as the enforcement activity involved in each case. Medical examiner records were used to identify work-related deaths among adolescents ages 11-17 between 1990 and 2008 and child labor violations. Investigations from state and federal Departments of Labor (DOL) were used to determine inspection activity, identify OSHA violations, and confirm child labor violations. Fifty-two percent of cases involved one or more child labor violations. Nine cases were investigated by either the U.S. or North Carolina DOL; among them, four had child labor violations. Eleven cases were investigated by the North Carolina DOL and all involved OSHA violations. Significant child labor and OSHA violations exist in adolescent worker fatalities in North Carolina, and gaps exist in enforcement at both the federal and state level, signaling needed improvements in the protection of adolescent workers.

  3. Neoproterozoic Stromatolites and Microphytolites of the Spitsbergen Archipelago

    NASA Astrophysics Data System (ADS)

    Anisimov, Artem; Anisimova, Svetlana; Kosteva, Natalia

    2017-04-01

    The Svalbard archipelago is located in the extreme North-West of the Barents Sea. On the archipelago in the framework of large-scale exploration of the continental shelf exploration work carried out by employees of the Polar Marine Geological Expedition (PMGE). The authors were further explored and tested the Neoproterozoic sections of the Groups Veteranen, Akademikarbreen and Polarisbreen on the East and West banks of the Sorgfjorden (the Northern part of the Ny Friesland Peninsula) and in the moraine of the glacier Duner. The rocks carbonate-terrigenous Veteranen Group (upper Riphean) is set in the rocky outcrops on the Western and Eastern banks of Sorgfjorden and in ice-dressed rocks of the Bay. The Group consists of four Formations (bottom to top): Kortbreen, Kingbreen, Glasgowbreen and Oxfordbreen. The rocks carbonate-terrigenous Akademikarbreen Group (upper Riphean) have a lower areal distribution than the breed Veteranen Group in the project area is established only in the southern part of the Bay, in the valleys Kluftdalen, Rivnedalen and small-unnamed streams, as well as on the plateau Fleinfjellet and Vidarfjellet. The Groups consists of four formation (bottom to top): Grusdievbreen, Svanbergfjellet, Draken and Backlundtoppen. According to previous researchers, limestone in Kingbreen Formation (Veteranen Group) met with radial-rayed Microphytolites group Radiosus. And in light grey, cream, pink and red limestones of the Academikarbreen Group, in the Svanbergfjellet Formation defined columnar branching Stromatolites Inzeria djejimi Raab., Gymnosolen aff. ramsayi Steinm. Stromatolites of Conophyton miloradovichi Raab. in the dolomites of the overlying sediments Draken and Backlundtoppen Formations contain Vendian the bubbles Microphytolites Vesicularites bothrydioformis Krasnop. In carbonate rocks of the Akademikerbreen Group were confirmed by the finds of Neoproterozoic microbial entities identified by previous researchers, and identified new locations of columnar Stromatolites of the Conophyton garganicus Kor., columnar Stromatolites of the group Anabaria sp., Inseria chunnbergica Gol, Balcalia mariinica Dol., Lenia jacutica Dol., dome-columnar Stromatolites Tinnia patomica Dol. and formation Stromatolites Stratifera baracunica Dol. In the few carbonate interbeds of the Veteranen Group were found concentric layered Microphytolites of Osagia genuses. Upper Riphean sections of the Spitsbergen archipelago based on the paleontological and lithological-facial characteristics are correlated confidently with complex of Phytolites of the Riphean stratotype of the southern Urals of Russia. The results of the new biostratigraphic data can be used for paleogeographic reconstruction and recovery lithofacies of the Neoproterozoic of Spitsbergen. In future studies it is desirable to conduct mapping of fossil organogenic structures, setting their length, width, length, relationship with host sediments. This may have importance both for the solution of fundamental questions of evolution of life on Earth, and in the search of minerals such as manganese, cobalt, phosphorite, oil, natural gas.

  4. Computations of ideal and real gas high altitude plume flows

    NASA Technical Reports Server (NTRS)

    Feiereisen, William J.; Venkatapathy, Ethiraj

    1988-01-01

    In the present work, complete flow fields around generic space vehicles in supersonic and hypersonic flight regimes are studied numerically. Numerical simulation is performed with a flux-split, time asymptotic viscous flow solver that incorporates a generalized equilibrium chemistry model. Solutions to generic problems at various altitude and flight conditions show the complexity of the flow, the equilibrium chemical dissociation and its effect on the overall flow field. Viscous ideal gas solutions are compared against equilibrium gas solutions to illustrate the effect of equilibrium chemistry. Improved solution accuracy is achieved through adaptive grid refinement.

  5. EARLY VERSUS LATE MRI IN ASPHYXIATED NEWBORNS TREATED WITH HYPOTHERMIA

    PubMed Central

    Wintermark, Pia; Hansen, Anne; Soul, Janet; Labrecque, Michelle; Robertson, Richard L.; Warfield, Simon K.

    2012-01-01

    Objective The purposes of this feasibility study are to assess: (1) the potential utility of early brain magnetic resonance imaging (MRI) in asphyxiated newborns treated with hypothermia; (2) whether early MRI predicts later brain injury observed in these newborns after hypothermia is completed; and (3) whether early MRI indicators of brain injury in these newborns represent reversible changes. Patients and Methods All consecutive asphyxiated term newborns meeting the criteria for therapeutic hypothermia were enrolled prospectively. Each of them underwent 1–2 “early” MRI scans while receiving hypothermia, on day of life (DOL) 1 and DOL 2–3, and also 1–2 “late” MRI scans on DOL 8–13 and at 1 month of age. Results Thirty-seven MRI scans were obtained in twelve asphyxiated neonates treated with induced hypothermia. Four newborns did develop MRI evidence of brain injury, already visible on early MRI scans. The remaining eight newborns did not develop significant MRI evidence of brain injury on any of the MRI scans. In addition, two patients displayed unexpected findings on early MRIs, leading to early termination of hypothermia treatment. Conclusions MRI scans obtained on DOL 2–3 during hypothermia seem to predict later brain injuries in asphyxiated newborns in this feasibility study. Brain injuries identified during this early time appear to represent irreversible changes. Early MRI scans might also be useful to demonstrate unexpected findings not related to hypoxic-ischemic encephalopathy, which could potentially be exacerbated by induced hypothermia. Additional studies with larger numbers of patients will be useful to more definitively confirm these results. PMID:20688865

  6. DOLICHOL PHOSPHATE MANNOSE SYNTHASE1 Mediates the Biogenesis of Isoprenyl-Linked Glycans and Influences Development, Stress Response, and Ammonium Hypersensitivity in Arabidopsis[W

    PubMed Central

    Jadid, Nurul; Mialoundama, Alexis Samba; Heintz, Dimitri; Ayoub, Daniel; Erhardt, Mathieu; Mutterer, Jérôme; Meyer, Denise; Alioua, Abdelmalek; Van Dorsselaer, Alain; Rahier, Alain; Camara, Bilal; Bouvier, Florence

    2011-01-01

    The most abundant posttranslational modification in nature is the attachment of preassembled high-mannose-type glycans, which determines the fate and localization of the modified protein and modulates the biological functions of glycosylphosphatidylinositol-anchored and N-glycosylated proteins. In eukaryotes, all mannose residues attached to glycoproteins from the luminal side of the endoplasmic reticulum (ER) derive from the polyprenyl monosaccharide carrier, dolichol P-mannose (Dol-P-Man), which is flipped across the ER membrane to the lumen. We show that in plants, Dol-P-Man is synthesized when Dol-P-Man synthase1 (DPMS1), the catalytic core, interacts with two binding proteins, DPMS2 and DPMS3, that may serve as membrane anchors for DPMS1 or provide catalytic assistance. This configuration is reminiscent of that observed in mammals but is distinct from the single DPMS protein catalyzing Dol-P-Man biosynthesis in bakers’ yeast and protozoan parasites. Overexpression of DPMS1 in Arabidopsis thaliana results in disorganized stem morphology and vascular bundle arrangements, wrinkled seed coat, and constitutive ER stress response. Loss-of-function mutations and RNA interference–mediated reduction of DPMS1 expression in Arabidopsis also caused a wrinkled seed coat phenotype and most remarkably enhanced hypersensitivity to ammonium that was manifested by extensive chlorosis and a strong reduction of root growth. Collectively, these data reveal a previously unsuspected role of the prenyl-linked carrier pathway for plant development and physiology that may help integrate several aspects of candidate susceptibility genes to ammonium stress. PMID:21558543

  7. Generic Hypersonic Inlet Module Analysis

    NASA Technical Reports Server (NTRS)

    Cockrell, Chares E., Jr.; Huebner, Lawrence D.

    2004-01-01

    A computational study associated with an internal inlet drag analysis was performed for a generic hypersonic inlet module. The purpose of this study was to determine the feasibility of computing the internal drag force for a generic scramjet engine module using computational methods. The computational study consisted of obtaining two-dimensional (2D) and three-dimensional (3D) computational fluid dynamics (CFD) solutions using the Euler and parabolized Navier-Stokes (PNS) equations. The solution accuracy was assessed by comparisons with experimental pitot pressure data. The CFD analysis indicates that the 3D PNS solutions show the best agreement with experimental pitot pressure data. The internal inlet drag analysis consisted of obtaining drag force predictions based on experimental data and 3D CFD solutions. A comparative assessment of each of the drag prediction methods is made and the sensitivity of CFD drag values to computational procedures is documented. The analysis indicates that the CFD drag predictions are highly sensitive to the computational procedure used.

  8. Long-term Stability of Vancomycin Hydrochloride in Glucose 5% Polyolefin Bags: The Brand Name Versus a Generic Product.

    PubMed

    Huvelle, Sophie; Godet, Marie; Hecq, Jean-Daniel; Gillet, Patricia; Jamart, Jacques; Galanti, Laurence M

    2016-01-01

    The objectives of this study were to determine if the preparation of vancomycin hydrochloride in advance of infusion could improve the quality of the drug, time management of drug delivery, cost savings of drug delivery, and to investigate the long-term stability of vancomycin hydrochloride (brand name Vancocin®) infusion in glucose 5% polyolefin bags versus the generic (Vancomycine®) at 5°C ± 3°C. Five bags of each infusion 1 g/100 mL vancomycin hydrochloride in 5% glucose (Vancocin ® and Vancomycine®) were stored up to 57 days at 5°C ± 3°C. A visual inspection and pH measurement were performed periodically during the storage, and the concentrations were measured by high-performance liquid chromatography-diode array detection. No color change or precipitation in the solution was observed throughout the study period. As recommended by the U.S. Food and Drug Administration, the lower confidence limit at 95% of the concentration for the solutions remained superior to 90% of the initial concentration up to 43 days for the brand vancomycin (Vancocin®) infusion (96% ± 2%) and up to 57 days for the generic (Vancomycine®) (95% ± 4%). The solutions prepared either from brand or generic vancomycin hydrochloride were chemically stable more than one month (43 days for the brand and 57 days for the generic solution) and could be prepared in advance in a centralized intravenous additive service facility. Copyright© by International Journal of Pharmaceutical Compounding, Inc.

  9. Professionally exempt nurses & the fee basis of payment.

    PubMed

    Bernard, Lucian J

    2003-09-01

    Within the home health industry, per-visit pay has long been used by agencies to compensate nurses. This "fee-based" system of compensation has been subject to scrutiny by the Department of Labor (DOL), which claims that this is not an appropriate method to compensate professional nurses who would qualify as "exempt" employees under the Fair Labor Standards Act. Recent court decisions have disagreed with the DOL's position on the issue, but home health agencies need to be careful about employee compensation statutes at both the federal and state level so as not to open themselves up to potentially devastating penalties.

  10. Comparative cost evaluation of brand name and generic ophthalmology medications in Ontario.

    PubMed

    Popovic, Marko; Chan, Clara; Lattanzio, Nisha; El-Defrawy, Sherif; Schlenker, Matthew B

    2018-04-01

    Medication cost for the same indication can vary considerably and can affect patient compliance. In this comparative cost analysis of commonly prescribed ophthalmology medications, the differences in cost between generic and brand name medications as well as different medications within an individual drug class were evaluated. Eye preparations from the Ontario Drug Benefit Formulary were identified, and further agents commonly prescribed by ophthalmologists were included. The standardized prescription drug cost, which includes the cost of the medication, mark-up, and dispensing cost, was provided by Ontario Shoppers Drug Mart stores in July 2016 for 103 common medications using typical dosages and durations. Based on medication class, the highest and lowest cost medications were antiallergy agents (Zaditor [ketotifen], Vasocon [naphazoline]), antibiotic ophthalmic solutions (Vigamox [moxifloxacin], generic ciprofloxacin), oral antibiotics (Cipro [ciprofloxacin], generic cephalexin), antibiotic ophthalmic ointments (generic erythromycin, Tobrex [tobramycin]), antiviral treatment (Valtrex [oral valacyclovir], Viroptic [topical trifluridine]), blepharitis treatment (Zithromax [oral azithromycin], generic oral tetracycline), beta-adrenergic inhibitors (Timoptic [topical timolol], generic topical timolol), topical prostaglandin analogues (Xalatan [latanoprost], generic travoprost), oral carbonic anhydrase inhibitors (methazolamide, acetazolamide), topical carbonic anhydrase solutions (Trusopt preservative-free [dorzolamide], Azopt [brinzolamide]), topical alpha-adrenergic agonists (Alphagan [brimonidine], generic brimonidine), topical muscarinic agonists (Isopto carpine [pilocarpine], Diocarpine [pilocarpine]), topical combination glaucoma agents (Cosopt [dorzolamide-timolol], generic dorzolamide-timolol), topical lubricants (Lacri-lube, Isopto tears), topical nonsteroidal anti-inflammatory drugs (Acuvail [ketorolac], Ilevro [nepafenac]), and steroids (Durezol [difluprednate], Pred mild [prednisolone]). Substantial cost differences exist between ophthalmology medications of the same class. We encourage ophthalmologists to be aware of the associated costs of the medications they prescribe and to use this information in their decision making. Copyright © 2018 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  11. Development of Multi-physics (Multiphase CFD + MCNP) simulation for generic solution vessel power calculation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Seung Jun; Buechler, Cynthia Eileen

    The current study aims to predict the steady state power of a generic solution vessel and to develop a corresponding heat transfer coefficient correlation for a Moly99 production facility by conducting a fully coupled multi-physics simulation. A prediction of steady state power for the current application is inherently interconnected between thermal hydraulic characteristics (i.e. Multiphase computational fluid dynamics solved by ANSYS-Fluent 17.2) and the corresponding neutronic behavior (i.e. particle transport solved by MCNP6.2) in the solution vessel. Thus, the development of a coupling methodology is vital to understand the system behavior at a variety of system design and postulated operatingmore » scenarios. In this study, we report on the k-effective (keff) calculation for the baseline solution vessel configuration with a selected solution concentration using MCNP K-code modeling. The associated correlation of thermal properties (e.g. density, viscosity, thermal conductivity, specific heat) at the selected solution concentration are developed based on existing experimental measurements in the open literature. The numerical coupling methodology between multiphase CFD and MCNP is successfully demonstrated, and the detailed coupling procedure is documented. In addition, improved coupling methods capturing realistic physics in the solution vessel thermal-neutronic dynamics are proposed and tested further (i.e. dynamic height adjustment, mull-cell approach). As a key outcome of the current study, a multi-physics coupling methodology between MCFD and MCNP is demonstrated and tested for four different operating conditions. Those different operating conditions are determined based on the neutron source strength at a fixed geometry condition. The steady state powers for the generic solution vessel at various operating conditions are reported, and a generalized correlation of the heat transfer coefficient for the current application is discussed. The assessment of multi-physics methodology and preliminary results from various coupled calculations (power prediction and heat transfer coefficient) can be further utilized for the system code validation and generic solution vessel design improvement.« less

  12. Potential Unintended Consequences of a Conservative Management Strategy for Patent Ductus Arteriosus.

    PubMed

    Elhoff, Justin J; Ebeling, Myla; Hulsey, Thomas C; Atz, Andrew M

    2016-01-01

    A recent review supports a strategy of deferring treatment of patent ductus arteriosus (PDA) in the preterm neonate until at least the second week after birth. In light of previous suggestion that later initiation of treatment may be less efficacious for closing PDAs it is reasonable to question if delayed treatment may be less effective. We conducted a single center retrospective review of a neonatal intensive care unit database of infants ≤37 weeks gestation with the diagnosis of PDA and treated with indomethacin from 1999 to 2007. We determined gestational age (GA), timing of indomethacin initiation, and status of the PDA at hospital discharge. Treatment failure was defined as neonates requiring further intervention to close their PDA or those who died without echo-proven PDA closure. Of the 341 infants meeting the study criteria, 77 (23%) had defined treatment failure. The failure group had a younger median GA of 25 weeks (interquartile range [IQR], 24-26) vs. 28 weeks (IQR, 26-30) for the successful group (P < .0001). The failure group had a median treatment initiation on day of life (DOL) 4 (IQR, 1-8) compared with DOL 3 (IQR, 1-6) for those in the successful group (P = .15). Taken as a whole, infants treated after DOL 5 were significantly more likely to have treatment failure (30.1% vs. 19.3% for those treated DOL 1-5, P = .03). Our study confirms that younger GA at birth is correlated with increased likelihood of failed PDA closure. We also show a trend indicating that later initiation of treatment may decrease the chances of successfully closing a PDA. Future examination of PDA management should consider the potential unintended consequences that may accompany a delayed treatment strategy. © 2015 Wiley Periodicals, Inc.

  13. Sustained hyperoxia-induced NF-κB activation improves survival and preserves lung development in neonatal mice

    PubMed Central

    McKenna, Sarah; Michaelis, Katherine A.; Agboke, Fadeke; Liu, Thanh; Han, Kristie; Yang, Guang; Dennery, Phyllis A.

    2014-01-01

    Oxygen toxicity contributes to the pathogenesis of bronchopulmonary dysplasia (BPD). Neonatal mice exposed to hyperoxia develop a simplified lung structure that resembles BPD. Sustained activation of the transcription factor NF-κB and increased expression of protective target genes attenuate hyperoxia-induced mortality in adults. However, the effect of enhancing hyperoxia-induced NF-κB activity on lung injury and development in neonatal animals is unknown. We performed this study to determine whether sustained NF-κB activation, mediated through IκBβ overexpression, preserves lung development in neonatal animals exposed to hyperoxia. Newborn wild-type (WT) and IκBβ-overexpressing (AKBI) mice were exposed to hyperoxia (>95%) or room air from day of life (DOL) 0–14, after which all animals were kept in room air. Survival curves were generated through DOL 14. Lung development was assessed using radial alveolar count (RAC) and mean linear intercept (MLI) at DOL 3 and 28 and pulmonary vessel density at DOL 28. Lung tissue was collected, and NF-κB activity was assessed using Western blot for IκB degradation and NF-κB nuclear translocation. WT mice demonstrated 80% mortality through 14 days of exposure. In contrast, AKBI mice demonstrated 60% survival. Decreased RAC, increased MLI, and pulmonary vessel density caused by hyperoxia in WT mice were significantly attenuated in AKBI mice. These findings were associated with early and sustained NF-κB activation and expression of cytoprotective target genes, including vascular endothelial growth factor receptor 2. We conclude that sustained hyperoxia-induced NF-κB activation improves neonatal survival and preserves lung development. Potentiating early NF-κB activity after hyperoxic exposure may represent a therapeutic intervention to prevent BPD. PMID:24748603

  14. Generic medicines: solutions for a sustainable drug market?

    PubMed

    Dylst, Pieter; Vulto, Arnold; Godman, Brian; Simoens, Steven

    2013-10-01

    Generic medicines offer equally high-quality treatment as originator medicines do at much lower prices. As such, they represent a considerable opportunity for authorities to obtain substantial savings. At the moment, the pharmaceutical landscape is changing and many pharmaceutical companies have altered their development and commercial strategies, combining both originator and generic divisions. In spite of this, the generic medicines industry is currently facing a number of challenges: delayed market access; the limited price differential with originator medicines; the continuous downwards pressure on prices; and the negative perception regarding generic medicines held by some key stakeholder groups. This could jeopardize the long-term sustainability of the generic manufacturing industry. Therefore, governments must focus on demand-side policies, alongside policies to accelerate market access, as the generic medicines industry will only be able to deliver competitive and sustainable prices if they are ensured a high volume. In the future, the generic medicines industry will increasingly look to biosimilars and generic versions of orphan drugs to expand their business.

  15. The physical properties of generic latanoprost ophthalmic solutions are not identical.

    PubMed

    Kolko, Miriam; Koch Jensen, Peter

    2017-06-01

    To compare various characteristics of Xalatan ® and five generic latanoprost ophthalmic solutions. Drop size, volume, pH values, buffer capacity, viscosity, hardness of bottles and costs were determined. Drop sizes were measured in triplicates by micropipettes, and the number of drops counted in three separate bottles of each generic product was determined. pH values were measured in triplicates by a calibrated pH meter. Buffer capacity was exploited by titrating known quantities of strong base into 2.5 ml of each brand and interpolated to neutral pH. Kinematic viscosity was determined by linear regression of timed gravity flow from a vertical syringe through a 21-G cannula. The hardness of the bottles was evaluated by gradually increasing tension on a hook placed around each bottle until a drop was expelled reading the tension on an attached spring scale. Drop sizes and the number of drops in the bottles varied significantly between the generic drugs. The control value of pH in the brand version (Xalatan ® ) was markedly lower compared to the generic latanoprost products. Titration of Xalatan ® to neutrality required substantially more NaOH compared to the generic latanoprost products. Finally, the viscosity revealed a significant variability between brands. Remarkable differences were found in bottle shapes, bottle hardness and costs of the latanoprost generics. Generic latanoprost eye drops should not be considered identical to the original brand version as regards to drop size, volumes, pH values, buffer capacity, viscosity, hardness of bottles and costs. It is likely that these issues affect compliance and intraocular pressure (IOP)-lowering effect. Therefore, re-evaluation of the requirements for introducing generic eye drops seems reasonable. © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  16. Experimentally determined biomediated Sr partition coefficient for dolomite: Significance and implication for natural dolomite

    NASA Astrophysics Data System (ADS)

    Sánchez-Román, Mónica; McKenzie, Judith A.; de Luca Rebello Wagener, Angela; Romanek, Christopher S.; Sánchez-Navas, Antonio; Vasconcelos, Crisógono

    2011-02-01

    Two strains of moderately halophilic bacteria were grown in aerobic culture experiments containing gel medium to determine the Sr partition coefficient between dolomite and the medium from which it precipitates at 15 to 45 °C. The results demonstrate that Sr incorporation in dolomite does occur not by the substitution of Ca, but rather by Mg. They also suggest that Sr partitioning between the culture medium and the minerals is better described by the Nernst equation ( DSrdol = Sr dol/Sr bmi), instead of the Henderson and Kracek equation ( DSrdol = (Sr/Ca) dol/(Sr/Ca) solution. The maximum value for DSrdol occurs at 15 °C in cultures with and without sulfate, while the minimum values occur at 35 °C, where the bacteria exhibit optimal growth. For experiments at 25, 35 and 45 °C, we observed that DSrdol values are greater in cultures with sulfate than in cultures without sulfate, whereas DSrdol values are smaller in cultures with sulfate than in cultures without sulfate at 15 °C. Together, our observations suggest that DSrdol is apparently related to microbial activity, temperature and sulfate concentration, regardless of the convention used to assess the DSrdol. These results have implications for the interpretation of depositional environments of ancient dolomite. The results of our culture experiments show that higher Sr concentrations in ancient dolomite could reflect microbial mediated primary precipitation. In contrast, previous interpretations concluded that high Sr concentrations in ancient dolomites are an indication of secondary replacement of aragonite, which incorporates high Sr concentrations in its crystal lattice, reflecting a diagenetic process.

  17. A high performance lithium–sulfur battery enabled by a fish-scale porous carbon/sulfur composite and symmetric fluorinated diethoxyethane electrolyte

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gao, Mengyao; Su, ChiCheung; He, Meinan

    A high performance lithium–sulfur (Li–S) battery comprising a symmetric fluorinated diethoxyethane electrolyte coupled with a fish-scale porous carbon/S composite electrode was demonstrated. 1,2-Bis(1,1,2,2-tetrafluoroethoxy)ethane (TFEE) was first studied as a new electrolyte solvent for Li–S chemistry. When co-mixed with 1,3-dioxolane (DOL), the DOL/TFEE electrolyte suppressed the polysulfide dissolution and shuttling reaction. Lastly, when coupled with a fish-scale porous carbon/S composite electrode, the Li–S cell exhibited a significantly high capacity retention of 99.5% per cycle for 100 cycles, which is far superior to the reported numerous systems.

  18. A high performance lithium–sulfur battery enabled by a fish-scale porous carbon/sulfur composite and symmetric fluorinated diethoxyethane electrolyte

    DOE PAGES

    Gao, Mengyao; Su, ChiCheung; He, Meinan; ...

    2017-03-07

    A high performance lithium–sulfur (Li–S) battery comprising a symmetric fluorinated diethoxyethane electrolyte coupled with a fish-scale porous carbon/S composite electrode was demonstrated. 1,2-Bis(1,1,2,2-tetrafluoroethoxy)ethane (TFEE) was first studied as a new electrolyte solvent for Li–S chemistry. When co-mixed with 1,3-dioxolane (DOL), the DOL/TFEE electrolyte suppressed the polysulfide dissolution and shuttling reaction. Lastly, when coupled with a fish-scale porous carbon/S composite electrode, the Li–S cell exhibited a significantly high capacity retention of 99.5% per cycle for 100 cycles, which is far superior to the reported numerous systems.

  19. Generic Wing-Body Aerodynamics Data Base

    NASA Technical Reports Server (NTRS)

    Holst, Terry L.; Olsen, Thomas H.; Kwak, Dochan (Technical Monitor)

    2001-01-01

    The wing-body aerodynamics data base consists of a series of CFD (Computational Fluid Dynamics) simulations about a generic wing body configuration consisting of a ogive-circular-cylinder fuselage and a simple symmetric wing mid-mounted on the fuselage. Solutions have been obtained for Nonlinear Potential (P), Euler (E) and Navier-Stokes (N) solvers over a range of subsonic and transonic Mach numbers and angles of attack. In addition, each solution has been computed on a series of grids, coarse, medium and fine to permit an assessment of grid refinement errors.

  20. Use of Flexible Body Coupled Loads in Assessment of Day of Launch Flight Loads

    NASA Technical Reports Server (NTRS)

    Starr, Brett R.; Yunis, Isam; Olds, Aaron D.

    2011-01-01

    A Day of Launch flight loads assessment technique that determines running loads calculated from flexible body coupled loads was developed for the Ares I-X Flight Test Vehicle. The technique was developed to quantify DOL flight loads in terms of structural load components rather than the typically used q-alpha metric to provide more insight into the DOL loads. In this technique, running loads in the primary structure are determined from the combination of quasi-static aerodynamic loads and dynamic loads. The aerodynamic loads are calculated as a function of time using trajectory parameters passed from the DOL trajectory simulation and are combined with precalculated dynamic loads using a load combination equation. The potential change in aerodynamic load due to wind variability during the countdown is included in the load combination. In the event of a load limit exceedance, the technique allows the identification of what load component is exceeded, a quantification of how much the load limit is exceeded, and where on the vehicle the exceedance occurs. This technique was used to clear the Ares I-X FTV for launch on October 28, 2009. This paper describes the use of coupled loads in the Ares I-X flight loads assessment and summarizes the Ares I-X load assessment results.

  1. "We are survivors and not a virus:" Content analysis of media reporting on Ebola survivors in Liberia.

    PubMed

    Mayrhuber, Elisabeth Anne-Sophie; Niederkrotenthaler, Thomas; Kutalek, Ruth

    2017-08-01

    The Ebola virus disease epidemic between 2013 and 2016 in West Africa was unprecedented. It resulted in approximately 28.000 cases and 10.000 Ebola survivors. Many survivors face social, economic and health-related predicaments and media reporting is crucially important in infectious disease outbreaks. However, there is little research on reporting of the social situation of Ebola survivors in Liberia. The study used a mixed methods approach and analysed media reports from the Liberian Daily Observer (DOL), a daily newspaper available online in English. We were interested to know how the situation of Ebola survivors was portrayed; in what way issues such as stigma and discrimination were addressed; and which stigma reduction interventions were covered and how. We included all articles on the situation of Ebola survivors in the quantitative and in-depth qualitative analysis published between April 2014 and March 2016. The DOL published 148 articles that portrayed the social situation of Ebola survivors between the 24 months observation period. In these articles, Ebola survivors were often defined beyond biological terms, reflecting on a broader social definition of survivorship. Survivorship was associated with challenges such as suffering from after-effects, social and economic consequences and psychological distress. Almost 50% of the articles explicitly mentioned stigmatisation in their reporting on Ebola survivors. This was contextualised in untrustworthiness towards international responses and the local health care system and inconclusive knowledge on cures and transmission routes. In the majority of DOL articles stigma reduction and engaging survivors in the response was reported as crucially important. Reporting in the DOL was educational-didactical and well-balanced in terms of disseminating available medical knowledge and reflecting the social situation of Ebola survivors. While the articles contextualised factors contributing to stigmatisation throughout the reporting, journalistic scrutiny regarding effectiveness of interventions by government and NGOs was missing.

  2. Confirmatory/release survey of the property at 71 Pearce Avenue (Former EAD Building) in Tonawanda, New York

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Salame-Alfie, A.; Alibozek, R.

    1995-12-31

    EAD Metallurgical, Inc., operated a facility in Tonawanda, New York, in which it utilized Americium 241 (Am-241) for the production of foil sources for use in smoke detectors. EAD was in operation between 1977 and 1983. By 1983, the company started losing money, and decided to relocate to Mexico. Before closing down its Tonawanda operation, however, it was required by the New York State Department of Labor (DOL) to decontaminate its facility to limits specified by DOL. No records of discharges to the sewer system were kept during this decontamination effort. Unsuccessful decontamination efforts by several EAD employees and contractorsmore » left the building contaminated, in particular the concrete floors and walls. To determine the scope of work for the decontamination project, staff from the New York State Departments of Health (DOH) and Environmental Conservation (DEC) conducted a Characterization Survey of the facility in 1993. This survey identified contamination levels of Am-241 in excess of release limits throughout the building, in the soil outside the facility, in pipes for sewage and interior drainage, and in an 8 x 8 x 11 foot sump pit in the building. DOH issued a request for proposals in early 1994 for the decontamination and subsequent decommissioning of the former EAD building, and NES/IES Inc. (NES) was awarded the contract to perform the remediation. DOH`s assignment was to provide an on-site presence to insure the completion of all agreed upon tasks, according to the terms of the contract and work plans submitted by NES. Additionally, the DOH staff acted as a liaison between NES, DOH, DEC and DOL central offices to review, comment and approve all changes or modifications to NES`s approach to the decontamination efforts. The assigned staff was also responsible for conducting confirmatory sampling and surveys of all areas deemed releasable to DOL and DEC criteria by NES.« less

  3. "We are survivors and not a virus:" Content analysis of media reporting on Ebola survivors in Liberia

    PubMed Central

    Mayrhuber, Elisabeth Anne-Sophie; Niederkrotenthaler, Thomas

    2017-01-01

    Background The Ebola virus disease epidemic between 2013 and 2016 in West Africa was unprecedented. It resulted in approximately 28.000 cases and 10.000 Ebola survivors. Many survivors face social, economic and health-related predicaments and media reporting is crucially important in infectious disease outbreaks. However, there is little research on reporting of the social situation of Ebola survivors in Liberia. Methods The study used a mixed methods approach and analysed media reports from the Liberian Daily Observer (DOL), a daily newspaper available online in English. We were interested to know how the situation of Ebola survivors was portrayed; in what way issues such as stigma and discrimination were addressed; and which stigma reduction interventions were covered and how. We included all articles on the situation of Ebola survivors in the quantitative and in-depth qualitative analysis published between April 2014 and March 2016. Results The DOL published 148 articles that portrayed the social situation of Ebola survivors between the 24 months observation period. In these articles, Ebola survivors were often defined beyond biological terms, reflecting on a broader social definition of survivorship. Survivorship was associated with challenges such as suffering from after-effects, social and economic consequences and psychological distress. Almost 50% of the articles explicitly mentioned stigmatisation in their reporting on Ebola survivors. This was contextualised in untrustworthiness towards international responses and the local health care system and inconclusive knowledge on cures and transmission routes. In the majority of DOL articles stigma reduction and engaging survivors in the response was reported as crucially important. Discussion Reporting in the DOL was educational-didactical and well-balanced in terms of disseminating available medical knowledge and reflecting the social situation of Ebola survivors. While the articles contextualised factors contributing to stigmatisation throughout the reporting, journalistic scrutiny regarding effectiveness of interventions by government and NGOs was missing. PMID:28837554

  4. Oxygen Isotope and Microtextural Evidence for Fluctuations in Fluid Pressure During Contact Metamorphism, Alta Aureole, Utah, USA

    NASA Astrophysics Data System (ADS)

    Bowman, J. R.; Valley, J. W.; Kita, N.

    2006-12-01

    Thin section-scale textures record a detailed history of prograde and retrograde reactions in the periclase (Per) zone of the Alta Stock aureole. New ion microprobe (SIMS) measurements (10 micron spot, ±0.2 permil, 1sd) of the oxygen isotope compositions of the carbonates preserving these textures provide evidence for at least two cycles of oscillation of fluid pressure (Pfl) between lithostatic (PL) and hydrostatic (Phyd) conditions during evolution of the inner aureole. Infiltration of water-rich fluids during prograde metamorphism converted dolomite (Dol) to Per + calcite (Cal) marble and caused significant 18O/16O depletion in the Dol protolith (Initial δ18O (Cal) > +25 permil), producing Cal with δ18O values of +11 permil. The SIMS values approximate oxygen isotope exchange equilibrium with the Alta stock, indicating that infiltrating fluids were likely magmatic. Exsolution of fluid from the crystallizing magma, coupled with geothermometry from the periclase zone marbles, requires Pfl> PL. Horizontally-oriented expansion cracks filled with brucite (Br) extend from Br pseudomorphs after periclase, and cut retrograde Dol that partially to completely rims the Br pseudomorphs. This earlier retrograde Dol is significantly depleted in 18O/16O relative to matrix Cal, with δ18O of +5 to +7.1 permil. These lower δ18O values indicate that meteoric water infiltrated into the Per marbles during cooling and resulting partial back reaction of Per + Cal to Dol, prior to the hydration of the remaining Per to Br. Influx of meteoric water requires sufficient increase in permeability to permit surface- derived meteoric water to penetrate to the estimated 4.5 km depth of this structural level of the Alta aureole, and suggests a resulting decrease in Pfl to hydrostatic pressure conditions. The horizontally-oriented expansion cracks associated with the Br pseudomorphs indicate that sub-vertical expansion accompanied hydration of Per to Br, requiring that Pfl increase again to values equal to and even slightly in excess of PL. Subsequent formation of a second generation of sub-vertical Dol veins with very low δ18O values (-1.9 to +1.2 permil) indicates another stage of infiltration involving even greater amounts of meteoric water, and a return to hydrostatic Pflconditions. Hence the detailed microtextures in the Per zone marbles, and their δ18O values, measureable with the spatial resolution capability of the ion microprobe, record a history of fluctuating fluid pressure between lithostatic and hydrostatic conditions in the inner Alta aureole. Such fluctuations should not be surprising. Contact metamorphic environments are characterized by strong spatial and temporal gradients in temperature, and a number of thermally-dependent factors (e.g., compaction, crystallization, reaction-generated porosity, thermally-controlled expansion and contraction) would then interact dynamically as sealing and cracking mechanisms to both increase and decrease permeability. Further, transient increases in fluid pressure would be expected from production of volatiles by metamorphic reactions and from multiple pulses of magmatic fluid produced during the assembly of an igneous intrusion.

  5. Charged rotating black holes in Einstein-Maxwell-Chern-Simons theory with a negative cosmological constant

    NASA Astrophysics Data System (ADS)

    Blázquez-Salcedo, Jose Luis; Kunz, Jutta; Navarro-Lérida, Francisco; Radu, Eugen

    2017-03-01

    We consider rotating black hole solutions in five-dimensional Einstein-Maxwell-Chern-Simons theory with a negative cosmological constant and a generic value of the Chern-Simons coupling constant λ . Using both analytical and numerical techniques, we focus on cohomogeneity-1 configurations, with two equal-magnitude angular momenta, which approach at infinity a globally anti-de Sitter background. We find that the generic solutions share a number of basic properties with the known Cvetič, Lü, and Pope black holes which have λ =1 . New features occur as well; for example, when the Chern-Simons coupling constant exceeds a critical value, the solutions are no longer uniquely determined by their global charges. Moreover, the black holes possess radial excitations which can be labelled by the node number of the magnetic gauge potential function. Solutions with small values of λ possess other distinct features. For instance, the extremal black holes there form two disconnected branches, while not all near-horizon solutions are associated with global solutions.

  6. 48 CFR 2942.1502 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ADMINISTRATION AND AUDIT SERVICES Contractor Performance Information 2942.1502 Policy. DOL contracting officers are required to use or interface with the Past Performance Information Retrieval System (PPIRS), and...

  7. 48 CFR 2942.1502 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ADMINISTRATION AND AUDIT SERVICES Contractor Performance Information 2942.1502 Policy. DOL contracting officers are required to use or interface with the Past Performance Information Retrieval System (PPIRS), and...

  8. 48 CFR 2942.1502 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ADMINISTRATION AND AUDIT SERVICES Contractor Performance Information 2942.1502 Policy. DOL contracting officers are required to use or interface with the Past Performance Information Retrieval System (PPIRS), and...

  9. 48 CFR 2942.1502 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ADMINISTRATION AND AUDIT SERVICES Contractor Performance Information 2942.1502 Policy. DOL contracting officers are required to use or interface with the Past Performance Information Retrieval System (PPIRS), and...

  10. 48 CFR 2942.1502 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ADMINISTRATION AND AUDIT SERVICES Contractor Performance Information 2942.1502 Policy. DOL contracting officers are required to use or interface with the Past Performance Information Retrieval System (PPIRS), and...

  11. Ineffective higher derivative black hole hair

    NASA Astrophysics Data System (ADS)

    Goldstein, Kevin; Mashiyane, James Junior

    2018-01-01

    Inspired by the possibility that the Schwarzschild black hole may not be the unique spherically symmetric vacuum solution to generalizations of general relativity, we consider black holes in pure fourth order higher derivative gravity treated as an effective theory. Such solutions may be of interest in addressing the issue of higher derivative hair or during the later stages of black hole evaporation. Non-Schwarzschild solutions have been studied but we have put earlier results on a firmer footing by finding a systematic asymptotic expansion for the black holes and matching them with known numerical solutions obtained by integrating out from the near-horizon region. These asymptotic expansions can be cast in the form of trans-series expansions which we conjecture will be a generic feature of non-Schwarzschild higher derivative black holes. Excitingly we find a new branch of solutions with lower free energy than the Schwarzschild solution, but as found in earlier work, solutions only seem to exist for black holes with large curvatures, meaning that one should not generically neglect even higher derivative corrections. This suggests that one effectively recovers the nonhair theorems in this context.

  12. Mercury in coals and fly ashes from Republika and Bobov dol thermoelectric power plants

    USGS Publications Warehouse

    Kostova, I.; Vassileva, C.; Hower, J.; Mastalerz, Maria; Vassilev, S.; Nikolova, N.

    2011-01-01

    Feed coal and y ash samples were collected at Republika and Bobov Dol thermoelectric power plants (TPPs). The y ashes (FAs) were collected fromthree rows of the hot-side electrostatic precipitators (ESPs) array. Each sam- ple was wet-screened at 100, 200, 325 and 500 mesh. The coals and y ashes were characterized with regard to their petrological and chemical composition (including mercury content) and to their surface area properties. The calculated enrichment factor (EF) shows that the Hg concentrations in the bulk coal samples from Republika and Bobov Dol TPPs are 2.19 and 1.41, respectively. In some coal size fractions the EF can be up to 4 times higher than the Clarke value. The calculated EF for fly ashes shows that the Hg concentrations in the bulk samples studied are lower (between 0.03 and 0.32) than the Clarke value. The most enriched in Hg are the fly ashes from the 3rd ESP row of Republika TPP. The Hg distribution in bulk FAs taken from dierent rows of the electrostatic precipitators of both TPPs studied shows well established tendency of gradual increase in the Hg content from the 1st to the 2nd and 3rd ESP rows. The correlation between Hg content and surface area, mesopore and micropore volume of y ashes was also done in the present investigation.

  13. 29 CFR 95.71 - Closeout procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-PROFIT ORGANIZATIONS, AND WITH COMMERCIAL ORGANIZATIONS, FOREIGN GOVERNMENTS, ORGANIZATIONS UNDER THE... recipient shall promptly refund any balances of unobligated cash that DOL has advanced or paid and that is...

  14. Solitons and black holes in non-Abelian Einstein-Born-Infeld theory

    NASA Astrophysics Data System (ADS)

    Dyadichev, V. V.; Gal'tsov, D. V.

    2000-08-01

    Recently it was shown that the Born-Infeld modification of the quadratic Yang-Mills action gives rise to classical particle-like solutions in the flat space which have a striking similarity with the Bartnik-McKinnon solutions obtained within the gravity coupled Yang-Mills theory. We show that both families of solutions are continuously related within the framework of the Einstein-Born-Infeld theory via interpolating sequences of parameters. We also investigate an internal structure of the associated black holes and find that the Born-Infeld non-linearity changes drastically the black hole interior typical for the usual quadratic Yang-Mills theory. In the latter case a generic solution exhibits violent metric oscillations near the singularity. In the Born-Infeld case the generic interior solution is smooth, the metric tends to the standard Schwarzschild type singularity, and we did not observe internal horizons. Smoothing of the `violent' EYM singularity may be interpreted as a result of non-gravitational quantum effects.

  15. Predictors of generic substitution: The role of psychological, sociodemographic, and contextual factors.

    PubMed

    Drozdowska, Aleksandra; Hermanowski, Tomasz

    2016-01-01

    Escalating pharmaceutical costs have become a global challenge for both governments and patients. Generic substitution is one way of decreasing these costs. The aim of this study was to investigate factors associated with patients' choice between generic drugs and innovator drugs. The survey was conducted in June 2013, 1000 people from across Poland were chosen as a representative population sample. The outcome (a preference for generics/a preference for innovator pharmaceuticals/no preference) was modeled by multinomial logistic regression, adjusted for several variables describing patients' sensitivity to selected generic features (price, brand, and country of origin), to third-party opinions about generics (information on generics in the mass media, opinions of health professionals (i.e. physicians, pharmacists), relatives/friends), as well as patients' personal experiences and income per household. The results supported the predictive capacity of most independent variables (except for patient sensitivity to the country of origin and to the information on generics in the mass media), denoting patients' preferences toward generic substitution. Patient sensitivity to recommendations by physicians, generic brand, and household income were the strongest predictors of the choice between generic and innovator pharmaceuticals (P < 0.001). The probability of choosing generics over innovator drugs was significantly higher among respondents with the lowest income levels, in those who were indifferent to generic brand or their physician's opinion, as well as in respondents who were sensitive to recommendations by pharmacists or attached a greater value to a past experience with generics (their own experience or that of relatives/friends). In consideration of the foregoing, awareness-raising campaigns may be recommended, supported by a variety of systemic solutions and tools to encourage generic substitution. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Licensing of Generic Medicines: Are There Any Challenges Left? A Pharmaceutical Regulatory Perspective.

    PubMed

    Borg, John Joseph; Tomasi, Paolo; Pani, Luca; Aislaitner, George; Pirozynski, Michal; Leufkens, Hubert; Melchiorri, Daniela

    2014-01-01

    When an innovative product (innovator) is not covered anymore by intellectual property rights, cheaper equivalent medicinal products (generic products) may be marketed and used in clinical practice. The regulation of generic products is well-established, and is primarily based on standard rules for quality, therapeutic equivalence requirements (the latter in most instances proven through a bioequivalence study), and safety data for the innovator. The extensive experience from bringing generic products to the market over the last decades allows the conclusion that they are well-accepted and provide a useful alternative option for cost-effective pharmacotherapy. While supporting this conclusion, there are a number of issues to be considered during the assessment of a generic product application. Six scenarios are described in total, from an efficacy and a safety perspective, where potential concerns with the current regulatory standards could arise in the approval of generic products. We also propose solutions to these scenarios in order to foster debate on these issues.

  17. 20 CFR 703.2 - Forms.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Insurance Carrier's Agreement and Undertaking. (5) LS-276 Application for Security Deposit Determination. (6... OWCP district offices and on the Internet at http://www.dol.gov/esa/owcp/dlhwc/lsforms.htm. ...

  18. 20 CFR 703.2 - Forms.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Insurance Carrier's Agreement and Undertaking. (5) LS-276 Application for Security Deposit Determination. (6... OWCP district offices and on the Internet at http://www.dol.gov/esa/owcp/dlhwc/lsforms.htm. ...

  19. 20 CFR 703.2 - Forms.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Insurance Carrier's Agreement and Undertaking. (5) LS-276 Application for Security Deposit Determination. (6... OWCP district offices and on the Internet at http://www.dol.gov/esa/owcp/dlhwc/lsforms.htm. ...

  20. GERICOS: A Generic Framework for the Development of On-Board Software

    NASA Astrophysics Data System (ADS)

    Plasson, P.; Cuomo, C.; Gabriel, G.; Gauthier, N.; Gueguen, L.; Malac-Allain, L.

    2016-08-01

    This paper presents an overview of the GERICOS framework (GEneRIC Onboard Software), its architecture, its various layers and its future evolutions. The GERICOS framework, developed and qualified by LESIA, offers a set of generic, reusable and customizable software components for the rapid development of payload flight software. The GERICOS framework has a layered structure. The first layer (GERICOS::CORE) implements the concept of active objects and forms an abstraction layer over the top of real-time kernels. The second layer (GERICOS::BLOCKS) offers a set of reusable software components for building flight software based on generic solutions to recurrent functionalities. The third layer (GERICOS::DRIVERS) implements software drivers for several COTS IP cores of the LEON processor ecosystem.

  1. 48 CFR 2901.201-1 - Maintenance of the FAR.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of the Division of Acquisition Management Services (DAMS), an organization within the Office of... Acquisition Council (CAAC). DAMS will be responsible for coordination with all interested DOL elements...

  2. 48 CFR 2901.602-1 - Authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and Responsibilities 2901.602-1... officers may be available for review on the Internet at http://www.dol.gov/oasam/grants/prgms.htm. To...

  3. a Generic Probabilistic Model and a Hierarchical Solution for Sensor Localization in Noisy and Restricted Conditions

    NASA Astrophysics Data System (ADS)

    Ji, S.; Yuan, X.

    2016-06-01

    A generic probabilistic model, under fundamental Bayes' rule and Markov assumption, is introduced to integrate the process of mobile platform localization with optical sensors. And based on it, three relative independent solutions, bundle adjustment, Kalman filtering and particle filtering are deduced under different and additional restrictions. We want to prove that first, Kalman filtering, may be a better initial-value supplier for bundle adjustment than traditional relative orientation in irregular strips and networks or failed tie-point extraction. Second, in high noisy conditions, particle filtering can act as a bridge for gap binding when a large number of gross errors fail a Kalman filtering or a bundle adjustment. Third, both filtering methods, which help reduce the error propagation and eliminate gross errors, guarantee a global and static bundle adjustment, who requires the strictest initial values and control conditions. The main innovation is about the integrated processing of stochastic errors and gross errors in sensor observations, and the integration of the three most used solutions, bundle adjustment, Kalman filtering and particle filtering into a generic probabilistic localization model. The tests in noisy and restricted situations are designed and examined to prove them.

  4. 29 CFR 502.2 - Coordination of intake between DOL agencies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED UNDER...) regarding contractual H-2A labor standards between the employer and the employee will be immediately...

  5. 48 CFR 1422.1003-4 - Administrative limitations, variations, tolerances and exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Service Contract Act of 1965, as Amended 1422.1003-4 Administrative limitations, variations, tolerances... Contract Act and exemptions directly to DOL, Administrator of the Wage and Hour Division. ...

  6. 20 CFR 638.200 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contractor that runs a center under an agreement or contract with DOL. Center review board means the group at... firearms and ammunition; explosives and incendiaries; knives with blades longer than 2” (two inches...

  7. 20 CFR 638.200 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... contractor that runs a center under an agreement or contract with DOL. Center review board means the group at... firearms and ammunition; explosives and incendiaries; knives with blades longer than 2” (two inches...

  8. 20 CFR 638.200 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... contractor that runs a center under an agreement or contract with DOL. Center review board means the group at... firearms and ammunition; explosives and incendiaries; knives with blades longer than 2” (two inches...

  9. 20 CFR 658.424 - Federal hearings.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the complaints will be handled more expeditiously in this fashion. (d) At the DOL Administrative Law... conducted pursuant to this part, but rules or principles designed to assure production of the most credible...

  10. Exact solution of the XXX Gaudin model with generic open boundaries

    NASA Astrophysics Data System (ADS)

    Hao, Kun; Cao, Junpeng; Yang, Tao; Yang, Wen-Li

    2015-03-01

    The XXX Gaudin model with generic integrable open boundaries specified by the most general non-diagonal reflecting matrices is studied. Besides the inhomogeneous parameters, the associated Gaudin operators have six free parameters which break the U(1) -symmetry. With the help of the off-diagonal Bethe ansatz, we successfully obtained the eigenvalues of these Gaudin operators and the corresponding Bethe ansatz equations.

  11. 20 CFR 703.2 - Forms.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Insurance Carrier's Agreement and Undertaking. (5) LS-276 Application for Security Deposit Determination. (6... Internet at http://www.dol.gov/owcp/dlhwc. [70 FR 43233, July 26, 2005, as amended at 77 FR 37286, June 21...

  12. 20 CFR 703.2 - Forms.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Insurance Carrier's Agreement and Undertaking. (5) LS-276 Application for Security Deposit Determination. (6... Internet at http://www.dol.gov/owcp/dlhwc. [70 FR 43233, July 26, 2005, as amended at 77 FR 37286, June 21...

  13. 42 CFR 81.12 - Procedure to update NIOSH-IREP.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...., National Academy of Sciences), (4) DOL, (5) Public comment. (c) NIOSH will submit substantive changes to... materials and providing public comment in the notice announcing the Advisory Board meeting, published in the...

  14. 20 CFR 658.425 - Decision of DOL Administrative Law Judge.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Job Service Complaint System Federal Js Complaint... jursidiction to consider the validity or constitutionality of JS regulations or of the Federal statutes under...

  15. Brain Perfusion In Asphyxiated Newborns Treated with Therapeutic Hypothermia

    PubMed Central

    Wintermark, Pia; Hansen, Anne; Gregas, Matthew C.; Soul, Janet; Labrecque, Michelle; Robertson, Richard L.; Warfield, Simon K.

    2012-01-01

    Background and Purpose Induced hypothermia is thought to work partly by mitigating reperfusion injury in asphyxiated term newborns. The purpose of this study is to assess brain perfusion in the first week of life in these newborns. Patients and Methods In this prospective cohort study, magnetic resonance imaging (MRI) and perfusion imaging by arterial spin labeling (ASL-PI) was used to assess brain perfusion in these newborns. We measured regional cerebral blood flow values on 1–2 MRIs obtained during the first week of life and compared them to values obtained in control term newborns. The same or later MRI scans were obtained to define the extent of brain injury. Results Eighteen asphyxiated and four control term newborns were enrolled; eleven asphyxiated newborns were treated with hypothermia. Those developing brain injury despite being treated with induced hypothermia usually displayed hypoperfusion on day of life (DOL) 1, and then hyperperfusion on DOL 2–3 in brain areas subsequently exhibiting injury. Asphyxiated newborns not treated with hypothermia who developed brain injury also displayed hyperperfusion on DOL 1–6 in brain areas displaying injury. Conclusions Our data show that ASL-PI may be useful for identifying asphyxiated newborns at risk of developing brain injury, whether or not hypothermia is administered. Since hypothermia for 72 hours may not prevent brain injury when hyperperfusion is found early in the course of neonatal hypoxic-ischemic encephalopathy, such newborns may be candidates for adjustments in their hypothermia therapy or for adjunctive neuroprotective therapies. PMID:21979494

  16. Qualitative analysis of Kantowski-Sachs metric in a generic class of f(R) models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leon, Genly; Roque, Armando A., E-mail: genly.leon@ucv.cl, E-mail: arestrada@ucf.edu.cu

    2014-05-01

    In this paper we investigate, from the dynamical systems perspective, the evolution of a Kantowski-Sachs metric in a generic class of f(R) models. We present conditions (i.e., differentiability conditions, existence of minima, monotony intervals, etc.) for a free input function related to the f(R), that guarantee the asymptotic stability of well-motivated physical solutions, specially, self-accelerated solutions, allowing to describe both inflationary- and late-time acceleration stages of the cosmic evolution. We discuss which f(R) theories allows for a cosmic evolution with an acceptable matter era, in correspondence to the modern cosmological paradigm. We find a very rich behavior, and amongst othersmore » the universe can result in isotropized solutions with observables in agreement with observations, such as de Sitter, quintessence-like, or phantom solutions. Additionally, we find that a cosmological bounce and turnaround are realized in a part of the parameter-space as a consequence of the metric choice.« less

  17. Thiolated graphene - a new platform for anchoring CdSe quantum dots for hybrid heterostructures

    NASA Astrophysics Data System (ADS)

    Debgupta, Joyashish; Pillai, Vijayamohanan K.

    2013-04-01

    Effective organization of small CdSe quantum dots on graphene sheets has been achieved by a simple solution exchange with thiol terminated graphene prepared by diazonium salt chemistry. This generic methodology of CdSe QD attachment to any graphene surface has remarkable implications in designing hybrid heterostructures.Effective organization of small CdSe quantum dots on graphene sheets has been achieved by a simple solution exchange with thiol terminated graphene prepared by diazonium salt chemistry. This generic methodology of CdSe QD attachment to any graphene surface has remarkable implications in designing hybrid heterostructures. Electronic supplementary information (ESI) available. See DOI: 10.1039/c3nr00363a

  18. Alternative Fuels Data Center

    Science.gov Websites

    Conference on Weights and Measures has established equivalent measures. Until the DOL standardizes measurements, a gasoline gallon equivalent is equal to 5.66 pounds (lbs.) of CNG and a diesel gallon equivalent

  19. 78 FR 25477 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Trade Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Federal agencies, and to improve the effectiveness of job training programs. This ICR requests minor... of Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored information...

  20. Geochemistry of the 2012-2013 Tolbachik Fissure eruption (Kamchatka, Russia)

    NASA Astrophysics Data System (ADS)

    Volynets, Anna; Melnikov, Dmitry; Belousov, Alexander; Belousova, Marina; Yakushev, Anton

    2014-05-01

    From November 27th, 2012, until the beginning of September 2013, a fissure eruption at the southern slope of Ploskiy Tolbachik volcano, Kamchatka, produced more than 0.52 km3 of lava (Dvigalo et al., 2014) and covered the area about 36 km2. The eruption was named as "The Institute of Volcanology and Seismology 50th Anniversary Fissure Tolbachik Eruption" (FTE-50). This is a manifestation of the ongoing high activity in Tolbachinskiy Dol (monogenetic zone around Ploskiy Tolbachik stratovolcano), which already produced in Holocene a lava field, covering more than 900 km2. FTE-50 lasted 9 months and exhibited some peculiar features, allowing us to distinguish it as a unique for Tolbachinskiy Dol: seismic activity only in the low energy class during 5 month prior to eruption (Kugaenko et al., 2013), the unusually high discharge rate at the beginning of the eruption (about 400 m3/sec), specific geochemical composition of the erupted lava. The eruption started from two vents, named after eminent Russian volcanologists as Menyailov (upper) and Naboko (lower) vents, and after three days all activity concentrated in the lower (Naboko) vent. All products of FTE-50 are richer in alkalis and TiO2 than previously studied lavas of Tolbachinskiy Dol. After the drastic change in composition at the beginning of the eruption, associated with the shift of the eruption center from the Menyailov to Naboko vent, when silica content dropped up to 2 wt.%, the composition remained practically constant until at least May 2013. Lavas of the Menyailov Vent are more acid than any of the earlier erupted rocks of the monogenetic zone (SiO2 up to 55.35 wt.%). Lavas of the Naboko Vent, at silica content close to the Southern Vent of the Great Fissure Tolbachik Eruption (1975-76) and other alumina-rich basaltic andesites of the Dol (52.5 wt.% in average in Naboko vent lavas vs. 51.8 wt.% in high-Al lavas from Tolb.Dol), have lowered concentrations of Al2O3 (16.3 wt.% vs. 17.1 wt/%), CaO (7.5 wt.% vs. 9 wt.%), MgO (4.1 wt.% vs. 5.5 wt.%). Trace elements distribution in the FTE-50 lavas allows us to suppose that they are genetically connected to the sources of the Southern Vent of GFTE and other high-Al basalts. FTE-50 products are also similar to some of the high-K rocks of Ploskie Sopki massif (Churikova, 1993) and to the underlying Studyonaya river plateau basaltic andesites (unpublished own data) erupted 262 Ka ago (Calkins et al., 2004), and fit their evolution trends, but differ from them by several elements, most prominently by higher Ti content. The basaltic trachyandesites of FTE-50 have higher REE, Y, Nb, Hf, Zr, Ta, Ti than all previously studied GFTE rocks; Nb, Ta, Ti in them are also higher than in high-K volcanic rocks of Ploskie Sopki massif.

  1. 78 FR 61397 - Stand Down Grant Requests; Extension of Availability of Funds

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... training, counseling, and placement services (including job readiness and literacy and skills training) to... Training (DVET) for your state. You will find address and contact information for DVET(s) at http://www.dol...

  2. 29 CFR 501.1 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administration (ETA). The issuance and denial of labor certification under 8 U.S.C. 1188 has been delegated by the Secretary to ETA, an agency within the U.S. Department of Labor (the Department or DOL), who in...

  3. 20 CFR 670.120 - What definitions apply to this part?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... agency, or a contractor that runs a center under an agreement or contract with DOL. Civilian conservation... incendiaries; (3) Knives with blades longer than 2 inches; (4) Homemade weapons; (5) All other weapons and...

  4. 20 CFR 670.120 - What definitions apply to this part?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... agency, or a contractor that runs a center under an agreement or contract with DOL. Civilian conservation... incendiaries; (3) Knives with blades longer than 2 inches; (4) Homemade weapons; (5) All other weapons and...

  5. 20 CFR 670.120 - What definitions apply to this part?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... agency, or a contractor that runs a center under an agreement or contract with DOL. Civilian conservation... incendiaries; (3) Knives with blades longer than 2 inches; (4) Homemade weapons; (5) All other weapons and...

  6. 20 CFR 670.120 - What definitions apply to this part?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... agency, or a contractor that runs a center under an agreement or contract with DOL. Civilian conservation... incendiaries; (3) Knives with blades longer than 2 inches; (4) Homemade weapons; (5) All other weapons and...

  7. 20 CFR 670.120 - What definitions apply to this part?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... agency, or a contractor that runs a center under an agreement or contract with DOL. Civilian conservation... incendiaries; (3) Knives with blades longer than 2 inches; (4) Homemade weapons; (5) All other weapons and...

  8. 48 CFR 522.805 - Procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .../ofcpkeyp.htm. (c) The EEO poster required by FAR 22.805(b) can be found at: http://www.dol.gov/esa/regs/compliance/posters/pdf/eeopost.pdf. In addition to providing this poster to each non-exempt contractor, the...

  9. 48 CFR 522.805 - Procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .../ofcpkeyp.htm. (c) The EEO poster required by FAR 22.805(b) can be found at: http://www.dol.gov/esa/regs/compliance/posters/pdf/eeopost.pdf. In addition to providing this poster to each non-exempt contractor, the...

  10. 48 CFR 522.805 - Procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .../ofcpkeyp.htm. (c) The EEO poster required by FAR 22.805(b) can be found at: http://www.dol.gov/esa/regs/compliance/posters/pdf/eeopost.pdf. In addition to providing this poster to each non-exempt contractor, the...

  11. 48 CFR 522.805 - Procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .../ofcpkeyp.htm. (c) The EEO poster required by FAR 22.805(b) can be found at: http://www.dol.gov/esa/regs/compliance/posters/pdf/eeopost.pdf. In addition to providing this poster to each non-exempt contractor, the...

  12. 75 FR 60249 - Federal Acquisition Regulation; Equal Opportunity for Veterans

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... Secretary of Labor (see http://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm . (b) The Act requires... ). 22.1307 [Amended] 0 9. Amend section 22.1307 by removing the words ``Special Disabled Veterans...

  13. Capitalizing on Federal Agencies' Intentions To Protect Youth Working in Agriculture.

    PubMed

    Murphy, Dennis J

    2017-01-01

    Nearly 750,000 youth work on farms across the United States. The U.S. Department of Labor's (U.S. DOL) Fair Labor Standards Act (FLSA) Hazardous Occupations Orders for Agriculture (HOOA) applies to approximately 37% of these youth. The HOOA regulations had not been updated since their inception in the late 1960s and the early 1970s. An attempt by U.S. DOL to update the regulations in 2011 was met with fierce opposition by the agricultural community, and the proposed updated regulations were withdrawn. One impactful outcome of these two events was a rededication by USDA and the farm community to address agricultural youth farm safety through education rather than through regulation. An agriculturally based National Steering Committee has developed consensus Belief Statements and Guiding Principles to proactively influence agricultural youth safety. In this case, USDA was clearly a 'sphere of influence' for youth agricultural safety.

  14. [The effect of tobacco prices on consumption: a time series data analysis for Mexico].

    PubMed

    Olivera-Chávez, Rosa Itandehui; Cermeño-Bazán, Rodolfo; de Miera-Juárez, Belén Sáenz; Jiménez-Ruiz, Jorge Alberto; Reynales-Shigematsu, Luz Myriam

    2010-01-01

    To estimate the price elasticity of the demand for cigarettes in Mexico based on data sources and a methodology different from the ones used in previous studies on the topic. Quarterly time series of consumption, income and price for the time period 1994 to 2005 were used. A long-run demand model was estimated using Ordinary Least Squares (OLS) and the existence of a cointegration relationship was investigated. Also, a model using Dinamic Ordinary Least Squares (DOLS) was estimated to correct for potential endogeneity of independent variables and autocorrelation of the residuals. DOLS estimates showed that a 10% increase in cigarette prices could reduce consumption in 2.5% (p<0.05) and increase government revenue in 16.11%. The results confirmed the effectiveness of taxes as an instrument for tobacco control in Mexico. An increase in taxes can be used to increase cigarette prices and therefore to reduce consumption and increase government revenue.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bena, Iosif; Kraus, Per; Warner, Nicholas P.

    We construct the most generic three-charge, three-dipole-charge, BPS black-ring solutions in a Taub-NUT background. These solutions depend on seven charges and six moduli, and interpolate between a four-dimensional black hole and a five-dimensional black ring. They are also instrumental in determining the correct microscopic description of the five-dimensional BPS black rings.

  16. Kmonodium, a Program for the Numerical Solution of the One-Dimensional Schrodinger Equation

    ERIC Educational Resources Information Center

    Angeli, Celestino; Borini, Stefano; Cimiraglia, Renzo

    2005-01-01

    A very simple strategy for the solution of the Schrodinger equation of a particle moving in one dimension subjected to a generic potential is presented. This strategy is implemented in a computer program called Kmonodium, which is free and distributed under the General Public License (GPL).

  17. The differences between the branded and generic medicines using solid dosage forms: In-vitro dissolution testing

    PubMed Central

    Al Ameri, Mubarak Nasser; Nayuni, Nanda; Anil Kumar, K.G.; Perrett, David; Tucker, Arthur; Johnston, Atholl

    2011-01-01

    Introduction Dissolution is the amount of substance that goes into solution per unit time under standardised conditions of liquid/solid interface, solvent composition and temperature. Dissolution is one of the most important tools to predict the in-vivo bioavailability and in some cases to determine bioequivalence and assure interchangeability. Aim To compare the differences in dissolution behaviour of solid dosage forms between innovators (reference products) and their generic counterparts (tested products). Methods Four replicates for each batch of 37 tested medicines was carried out using A PT-DT70 dissolution tester from Pharma Test. A total of 13 branded medicines and 24 generic counterparts were obtained locally and internationally to detect any differences in their dissolution behaviour. They were tested according to the British Pharmacopeia, European Pharmacopeia and the US Pharmacopeia with the rate of dissolution determined by ultra-violet Spectrophotometery. Results Most tested medicines complied with the pharmacopoeial specifications and achieved 85% dissolution in 60 min. However, some generic medicines showed significant differences in dissolution rate at 60 and 120 min. Many generic medicines showed a slower dissolution rate than their branded counterparts such as the generic forms of omeprazole 20 mg. Some showed an incomplete dissolution such as the generic form of nifedipine 10 mg. Other generics showed faster dissolution rate than their branded counterpart such as the generic forms of meloxicam 15 mg. Moreover, some generics from different batches of the same manufacturer showed significant differences in their dissolution rate such as the generic forms of meloxicam 7.5 mg. Nevertheless, some generic medicines violated the EMA and the FDA guidelines for industry when they failed to achieve 85% dissolution at 60 min, such as the generic form of diclofenac sodium 50 mg. Conclusion Most medicines in this study complied with the pharmacopeial limits. However, some generics dissolved differently than their branded counterparts. This can clearly question the interchangeability between the branded and its generic counterpart or even among generics. PMID:25755988

  18. Pulsed plane wave analytic solutions for generic shapes and the validation of Maxwell's equations solvers

    NASA Technical Reports Server (NTRS)

    Yarrow, Maurice; Vastano, John A.; Lomax, Harvard

    1992-01-01

    Generic shapes are subjected to pulsed plane waves of arbitrary shape. The resulting scattered electromagnetic fields are determined analytically. These fields are then computed efficiently at field locations for which numerically determined EM fields are required. Of particular interest are the pulsed waveform shapes typically utilized by radar systems. The results can be used to validate the accuracy of finite difference time domain Maxwell's equations solvers. A two-dimensional solver which is second- and fourth-order accurate in space and fourth-order accurate in time is examined. Dielectric media properties are modeled by a ramping technique which simplifies the associated gridding of body shapes. The attributes of the ramping technique are evaluated by comparison with the analytic solutions.

  19. Asymptotically flat, stable black hole solutions in Einstein-Yang-Mills-Chern-Simons theory.

    PubMed

    Brihaye, Yves; Radu, Eugen; Tchrakian, D H

    2011-02-18

    We construct finite mass, asymptotically flat black hole solutions in d=5 Einstein-Yang-Mills-Chern-Simons theory. Our results indicate the existence of a second order phase transition between Reissner-Nordström solutions and the non-Abelian black holes which generically are thermodynamically preferred. Some of the non-Abelian configurations are also stable under linear, spherically symmetric perturbations.

  20. Teaching Thermodynamics of Ideal Solutions: An Entropy-Based Approach to Help Students Better Understand and Appreciate the Subtleties of Solution Models

    ERIC Educational Resources Information Center

    Tomba, J. Pablo

    2015-01-01

    The thermodynamic formalism of ideal solutions is developed in most of the textbooks postulating a form for the chemical potential of a generic component, which is adapted from the thermodynamics of ideal gas mixtures. From this basis, the rest of useful thermodynamic properties can be derived straightforwardly without further hypothesis. Although…

  1. 42 CFR 82.4 - How Will DOL Use the Results of the NIOSH Dose Reconstructions?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... reconstruction results together with information on cancer diagnosis and other personal information provided to... probability that the cancer of the covered employee was caused by radiation exposure at a covered facility of...

  2. 42 CFR 82.4 - How Will DOL Use the Results of the NIOSH Dose Reconstructions?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... reconstruction results together with information on cancer diagnosis and other personal information provided to... probability that the cancer of the covered employee was caused by radiation exposure at a covered facility of...

  3. 76 FR 35915 - Proposed Information Collection Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... DEPARTMENT OF LABOR Office of Disability Employment Policy Proposed Information Collection Request... Disability Employment Policy (ODEP) of the Department of Labor (DOL) is soliciting comments concerning the... of Disability Employment Policy Disability Employment Initiative (DEI). A copy of the proposed...

  4. 76 FR 5403 - Office of the Secretary

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission for OMB Review; Comment Request; Regulations Containing Procedures for Handling of Retaliation Complaints ACTION: Notice. SUMMARY: The Department of Labor (DOL) hereby announces the submission of the...

  5. 42 CFR 82.4 - How Will DOL Use the Results of the NIOSH Dose Reconstructions?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... reconstruction results together with information on cancer diagnosis and other personal information provided to... probability that the cancer of the covered employee was caused by radiation exposure at a covered facility of...

  6. 42 CFR 82.4 - How Will DOL Use the Results of the NIOSH Dose Reconstructions?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... reconstruction results together with information on cancer diagnosis and other personal information provided to... probability that the cancer of the covered employee was caused by radiation exposure at a covered facility of...

  7. 42 CFR 82.4 - How Will DOL Use the Results of the NIOSH Dose Reconstructions?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... reconstruction results together with information on cancer diagnosis and other personal information provided to... probability that the cancer of the covered employee was caused by radiation exposure at a covered facility of...

  8. 20 CFR 667.170 - What responsibility review does the Department conduct for awards made under WIA title I...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... consider the organization's history with regard to the management of other grants, including DOL grants... fashion. (b) This responsibility review is independent of the competitive process. Applicants which are...

  9. CAP waveform estimation from the measured electrical bioimpedance values: Patient's heart rate variability analysis.

    PubMed

    Krivoshei, A; Uuetoa, H; Min, M; Annus, P; Uuetoa, T; Lamp, J

    2015-08-01

    The paper presents analysis of the generic transfer function (TF) between Electrical Bioimpedance (EBI) measured non-invasively on the wrist and Central Aortic Pressure (CAP) invasively measured at the aortic root. Influence of the Heart Rate (HR) variations on the generic TF and on reconstructed CAP waveforms is investigated. The HR variation analysis is provided on a single patient data to exclude inter-patient influences at the current research stage. A new approach for the generic TF estimating from a data ensemble is presented as well. Moreover, an influence of the cardiac period beginning point selection is analyzed and empirically optimal solution for its selection is proposed.

  10. Analyzing generic and branded substitution patterns in the Netherlands using prescription data.

    PubMed

    Pechlivanoglou, Petros; van der Veen, Willem Jan; Bos, Jens H; Postma, Maarten J

    2011-04-27

    As in other societies, pharmaceutical expenditures in the Netherlands are rising every year. As a consequence, needs for cost control are often expressed. One possible solution for cost control could come through increasing generic substitution by pharmacists. We aim to analyse the extent and nature of substitution in recent years and estimate the likelihood of generic or branded substitution in Dutch pharmacies in relation to various characteristics. We utilized a linked prescription dataset originating from a general practitioner (GP) and a pharmacy database, both from the northern Netherlands. We selected specific drugs of interest, containing about 55,000 prescriptions from 15 different classes. We used a crossed generalized linear mixed model to estimate the effects that certain patient and pharmacy characteristics as well as timing have on the likelihood that a prescription will eventually be substituted by the pharmacist. Generic substitution occurred at 25% of the branded prescriptions. Generic substitution was more likely to occur earlier in time after patent expiry and to patients that were older and more experienced in their drug use. Individually owned pharmacies had a lower probability of generic substitution compared to chain pharmacies. Oppositely, branded substitution occurred in 10% of generic prescriptions and was positively related to the patients' experience in branded use. Individually owned pharmacies were more likely to substitute a generic drug to a branded compared to other pharmacies. Antidepressant and PPI prescriptions were less prone to generic and more prone to branded substitution. Analysis of prescription substitution by the pharmacist revealed strong relations between substitution and patient experience on drug use, pharmacy status and timing. These findings can be utilised to design further strategies to enhance generic substitution.

  11. 76 FR 30970 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Standard on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ...: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health... Officer for the Department of Labor, Occupational Safety and Health Administration (OSHA), Office of... submission of responses. [[Page 30971

  12. 42 CFR 83.2 - How will DOL use the designations established under the procedures in this part?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES PROCEDURES FOR... for a qualified member of the Cohort with a specified cancer, pursuant to the procedures set forth in...

  13. 42 CFR 83.2 - How will DOL use the designations established under the procedures in this part?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES PROCEDURES FOR... for a qualified member of the Cohort with a specified cancer, pursuant to the procedures set forth in...

  14. 42 CFR 83.2 - How will DOL use the designations established under the procedures in this part?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES PROCEDURES FOR... for a qualified member of the Cohort with a specified cancer, pursuant to the procedures set forth in...

  15. 42 CFR 83.2 - How will DOL use the designations established under the procedures in this part?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES PROCEDURES FOR... for a qualified member of the Cohort with a specified cancer, pursuant to the procedures set forth in...

  16. 42 CFR 83.2 - How will DOL use the designations established under the procedures in this part?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES PROCEDURES FOR... for a qualified member of the Cohort with a specified cancer, pursuant to the procedures set forth in...

  17. 75 FR 3709 - Notice of Intent To Conduct Restoration Planning (Pursuant to 15 CFR 990.44)-Discharge of Oil...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ... Administration (``NOAA''); the United States Department of the Interior (``DOl''), acting through the National... restoration planning, (2) Ephemeral data, and/or (3) Information needed to design or implement anticipated...

  18. 78 FR 19315 - Office of the Secretary

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission for OMB Review; Comment Request: Multiple Worksite Report and the Report of Federal Employment and Wages ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Bureau of Labor...

  19. 77 FR 72410 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ... for OMB Review; Comment Request; Unemployment Insurance Title XII Advances and Voluntary Repayment..., ``Unemployment Insurance Title XII Advances and Voluntary Repayment Process,'' to the Office of Management and... submission of responses. Agency: DOL-ETA. [[Page 72411

  20. 29 CFR 2.35 - Effect of DOL support on Title VII employment nondiscrimination requirements and on other...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; Protection of Religious Liberty of Department of Labor Social Service Providers and Beneficiaries § 2.35... impairments may access this telephone number via TTY by calling the toll-free Federal Information Relay...

  1. 29 CFR 2.35 - Effect of DOL support on Title VII employment nondiscrimination requirements and on other...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...; Protection of Religious Liberty of Department of Labor Social Service Providers and Beneficiaries § 2.35... impairments may access this telephone number via TTY by calling the toll-free Federal Information Relay...

  2. Computational study of generic hypersonic vehicle flow fields

    NASA Technical Reports Server (NTRS)

    Narayan, Johnny R.

    1994-01-01

    The geometric data of the generic hypersonic vehicle configuration included body definitions and preliminary grids for the forebody (nose cone excluded), midsection (propulsion system excluded), and afterbody sections. This data was to be augmented by the nose section geometry (blunt conical section mated with the noncircular cross section of the forebody initial plane) along with a grid and a detailed supersonic combustion ramjet (scramjet) geometry (inlet and combustor) which should be merged with the nozzle portion of the afterbody geometry. The solutions were to be obtained by using a Navier-Stokes (NS) code such as TUFF for the nose portion, a parabolized Navier-Stokes (PNS) solver such as the UPS and STUFF codes for the forebody, a NS solver with finite rate hydrogen-air chemistry capability such as TUFF and SPARK for the scramjet and a suitable solver (NS or PNS) for the afterbody and external nozzle flows. The numerical simulation of the hypersonic propulsion system for the generic hypersonic vehicle is the major focus of this entire work. Supersonic combustion ramjet is such a propulsion system, hence the main thrust of the present task has been to establish a solution procedure for the scramjet flow. The scramjet flow is compressible, turbulent, and reacting. The fuel used is hydrogen and the combustion process proceeds at a finite rate. As a result, the solution procedure must be capable of addressing such flows.

  3. Bethe states of the trigonometric SU(3) spin chain with generic open boundaries

    NASA Astrophysics Data System (ADS)

    Sun, Pei; Xin, Zhirong; Qiao, Yi; Wen, Fakai; Hao, Kun; Cao, Junpeng; Li, Guang-Liang; Yang, Tao; Yang, Wen-Li; Shi, Kangjie

    2018-06-01

    By combining the algebraic Bethe ansatz and the off-diagonal Bethe ansatz, we investigate the trigonometric SU (3) model with generic open boundaries. The eigenvalues of the transfer matrix are given in terms of an inhomogeneous T - Q relation, and the corresponding eigenstates are expressed in terms of nested Bethe-type eigenstates which have well-defined homogeneous limit. This exact solution provides a basis for further analyzing the thermodynamic properties and correlation functions of the anisotropic models associated with higher rank algebras.

  4. Scattering transform for nonstationary Schroedinger equation with bidimensionally perturbed N-soliton potential

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boiti, M.; Pempinelli, F.; Pogrebkov, A. K.

    2006-12-15

    In the framework of the extended resolvent approach the direct and inverse scattering problems for the nonstationary Schroedinger equation with a potential being a perturbation of the N-soliton potential by means of a generic bidimensional smooth function decaying at large spaces are introduced and investigated. The initial value problem of the Kadomtsev-Petviashvili I equation for a solution describing N wave solitons on a generic smooth decaying background is then linearized, giving the time evolution of the spectral data.

  5. Composite structural materials

    NASA Technical Reports Server (NTRS)

    Loewy, R.; Wiberley, S. E.

    1986-01-01

    Overall emphasis is on basic long-term research in the following categories: constituent materials, composite materials, generic structural elements, processing science technology; and maintaining long-term structural integrity. Research in basic composition, characteristics, and processing science of composite materials and their constituents is balanced against the mechanics, conceptual design, fabrication, and testing of generic structural elements typical of aerospace vehicles so as to encourage the discovery of unusual solutions to present and future problems. Detailed descriptions of the progress achieved in the various component parts of this comprehensive program are presented.

  6. 78 FR 16856 - Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... Savings Plan Activity Reports by the Executive Director. a. Monthly Participant Activity Report. b. Monthly Investment Report. c. Legislative Report. 3. Shareholder Actions. 4. Demographics Report. 5. Audit Reports and DOL Presentation. Parts Closed to the Public 1. Security. CONTACT PERSON FOR MORE INFORMATION...

  7. 20 CFR 655.715 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Employment Standards Administration, DOL. Employed, employed by the employer, or employment relationship means the employment relationship as determined under the common law, under which the key determinant is... * * *. [A]ll of the incidents of the relationship must be assessed and weighed with no one factor being...

  8. 77 FR 34410 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Prohibited...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission... Separate Accounts ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Employee Benefits Security Administration (EBSA) sponsored information collection request (ICR) titled, ``Prohibited...

  9. 77 FR 21108 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Disability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-09

    ... for OMB Review; Comment Request; Disability Employment Initiative Evaluation ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Office of Disability Employment Policy (ODEP) sponsored information collection request (ICR) proposal titled, ``Disability Employment Initiative...

  10. 77 FR 65414 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; 1,3...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... collection requirements is to protect employees from the adverse health effects associated with occupational... respirator; establish medical surveillance programs to monitor employee health; and to provide employees with... Labor (DOL) is submitting the Occupational [[Page 65415

  11. Parallel-vector solution of large-scale structural analysis problems on supercomputers

    NASA Technical Reports Server (NTRS)

    Storaasli, Olaf O.; Nguyen, Duc T.; Agarwal, Tarun K.

    1989-01-01

    A direct linear equation solution method based on the Choleski factorization procedure is presented which exploits both parallel and vector features of supercomputers. The new equation solver is described, and its performance is evaluated by solving structural analysis problems on three high-performance computers. The method has been implemented using Force, a generic parallel FORTRAN language.

  12. Highly Accurate Beam Torsion Solutions Using the p-Version Finite Element Method

    NASA Technical Reports Server (NTRS)

    Smith, James P.

    1996-01-01

    A new treatment of the classical beam torsion boundary value problem is applied. Using the p-version finite element method with shape functions based on Legendre polynomials, torsion solutions for generic cross-sections comprised of isotropic materials are developed. Element shape functions for quadrilateral and triangular elements are discussed, and numerical examples are provided.

  13. Generic Drugs - Decreasing Costs and Room for Increased Number of Kidney Transplantations.

    PubMed

    Spasovski, Goce

    2015-01-01

    Kidney transplantation is the best treatment option in comparison to dialysis, although patients are obliged to receive life-long medical treatment with immunosuppressive drugs (ISDs) for prevention of the graft rejection. Such immunosuppressive treatment may be costly and associated with multiple adverse effects. Since costs are viewed as one of the major constraints for the increasing number of transplantation, the use of generic ISDs may decrease the overall cost of transplantation and raise the possibility for its further development. An ideal ISD should have the security margin between toxic and therapeutic dose, and prevent development of acute or chronic rejection of the transplanted kidney. This is particularly important for drugs with a "narrow therapeutical index" (NTI), where small differences in dose or concentration lead to dose and concentration-dependent, serious therapeutic failures and/or adverse drug reactions. The NTI generic drug is approved if within 90%-112% of the area under the curve of the original product the pharmacokinetics fulfills the strict criteria of pharmaceutical equivalence and bioequivalence. Every generic has to be proven to be bioequivalent to the innovator product, and not to other generic products because of the possible generic "drift". Thus, the generic ISDs may be economically attractive, but theoretically, they may pose a risk to transplant patients. Such risks may be reduced if a long-term clinical studies showing cost-effectiveness of generic ISDs in de novo and prevalent transplant patients for every new generic ISD are performed. In conclusion, the increased number of solid organ transplantation goes in line with the increased health care expenditure for ISDs. The generic immunosuppressants could be a possible solution if safely substituted for innovator products or other generic drug of choice. The substantial cost reduction needs to be redirected into organ donation initiatives so that more patients can benefit from the further increase in transplantation.

  14. Comparing Generic Drug Markets in Europe and the United States: Prices, Volumes, and Spending.

    PubMed

    Wouters, Olivier J; Kanavos, Panos G; McKEE, Martin

    2017-09-01

    Policy Points: Our study indicates that there are opportunities for cost savings in generic drug markets in Europe and the United States. Regulators should make it easier for generic drugs to reach the market. Regulators and payers should apply measures to stimulate price competition among generic drugmakers and to increase generic drug use. To meaningfully evaluate policy options, it is important to analyze historical context and understand why similar initiatives failed previously. Rising drug prices are putting pressure on health care budgets. Policymakers are assessing how they can save money through generic drugs. We compared generic drug prices and market shares in 13 European countries, using data from 2013, to assess the amount of variation that exists between countries. To place these results in context, we reviewed evidence from recent studies on the prices and use of generics in Europe and the United States. We also surveyed peer-reviewed studies, gray literature, and books published since 2000 to (1) outline existing generic drug policies in European countries and the United States; (2) identify ways to increase generic drug use and to promote price competition among generic drug companies; and (3) explore barriers to implementing reform of generic drug policies, using a historical example from the United States as a case study. The prices and market shares of generics vary widely across Europe. For example, prices charged by manufacturers in Switzerland are, on average, more than 2.5 times those in Germany and more than 6 times those in the United Kingdom, based on the results of a commonly used price index. The proportion of prescriptions filled with generics ranges from 17% in Switzerland to 83% in the United Kingdom. By comparison, the United States has historically had low generic drug prices and high rates of generic drug use (84% in 2013), but has in recent years experienced sharp price increases for some off-patent products. There are policy solutions to address issues in Europe and the United States, such as streamlining the generic drug approval process and requiring generic prescribing and substitution where such policies are not yet in place. The history of substitution laws in the United States provides insights into the economic, political, and cultural issues influencing the adoption of generic drug policies. Governments should apply coherent supply- and demand-side policies in generic drug markets. An immediate priority is to convince more physicians, pharmacists, and patients that generic drugs are bioequivalent to branded products. Special-interest groups continue to obstruct reform in Europe and the United States. © 2017 The Authors The Milbank Quarterly published by Wiley Periodicals, Inc. on behalf of The Millbank Memorial Fund.

  15. 48 CFR 22.608 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Walsh-Healey Public Contracts Act 22.608 Procedures. (a) Award. When a contract subject to the Act is awarded, the contracting officer, in accordance with... to the contractor DOL publication WH-1313, Notice to Employees Working on Government Contracts. (b...

  16. 29 CFR 95.21 - Standards for financial management systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS, AND WITH COMMERCIAL ORGANIZATIONS, FOREIGN GOVERNMENTS... the Federal Government guarantees or insures the repayment of money borrowed by the recipient, DOL, at... prescribed in 31 CFR part 223, “Surety Companies Doing Business with the United States.” ...

  17. 78 FR 77717 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Default...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission... Account Plans ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Employee Benefits Security Administration (EBSA) sponsored information collection request (ICR) titled, ``Default Investment...

  18. 75 FR 33203 - Funding Formula for Grants to States

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ... as Social Security numbers, birth dates, and medical data. Docket: To read or download submissions or... Local Area Unemployment Statistics (LAUS), both of which are compiled by DOL's Bureau of Labor Statistics. Specifies how each State's basic JVSG allocation is calculated. Identifies the procedures...

  19. 77 FR 12327 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ... Labor (DOL) is submitting the Occupational Safety and Health Administration sponsored information... Information and Regulatory Affairs, Attn: OMB Desk Officer for the Department of Labor, Occupational Safety... information technology, e.g., permitting electronic submission of responses. Agency: Occupational Safety and...

  20. 76 FR 5211 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Grantee...

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    .... Agency: Occupational Safety and Health Administration (OSHA). Title of Collection: Grantee Quarterly... Department of Labor (DOL) hereby announces the submission of the Occupational Safety and Health... Health Administration (OSHA), Office of Management and Budget, Room 10235, Washington, DC 20503...

  1. 78 FR 24437 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

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    ... of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored..., Occupational Safety and Health Administration (OSHA), Office of Management and Budget, Room 10235, Washington... submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Title of Collection...

  3. 20 CFR 632.34 - Program income.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Program income. 632.34 Section 632.34 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN... carry out the program, notwithstanding the expiration of DOL financial assistance for that program. (c...

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  5. International Inspiration

    ERIC Educational Resources Information Center

    Finkel, Ed

    2017-01-01

    As the U.S. Department of Labor (DOL) expands its Registered Apprenticeship College Consortium (RACC) among community colleges and employer partners, those involved are looking to countries like Germany and Switzerland for inspiration. In some cases, that has meant partnering with companies from those countries, which have had more comprehensive…

  6. 29 CFR 95.41 - Recipient responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Procurement Standards § 95.41 Recipient responsibilities. The standards contained in this section do not... the responsible authority, without recourse to DOL, regarding the settlement and satisfaction of all contractual and administrative issues arising out of procurements entered into in support of an award or other...

  7. 76 FR 60531 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Employee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ... for OMB Review; Comment Request; Employee Retirement Income Security Act Prohibited Transaction Exemption 86-128 ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Employee Benefits Security Administration sponsored information collection request (ICR) titled, ``Employee Retirement Income...

  8. 76 FR 56814 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Enhanced...

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    2011-09-14

    ... for OMB Review; Comment Request; Enhanced Traditional Jobs Demonstration ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored and proposed information collection request (ICR) titled, ``Enhanced Traditional Jobs Demonstration,'' to the...

  9. 77 FR 44288 - Agency Information Collection Activities; Submission for OMB Review; Comment Request: Definition...

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  10. 77 FR 35063 - Whistleblower Protection Advisory Committee

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  11. 48 CFR 2901.603-3 - Appointment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... all warrants above the micro-purchase threshold. In addition, appointments may be made for specific... functions. (a) Purchase Cards (micro-purchase threshold). Purchase cardholders will be appointed in accordance with the DOL Guidelines for Purchase Card Use and the Agency/Office procedures approved by the HCA...

  12. 78 FR 7815 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Gamma...

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    2013-02-04

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  14. Demonstration Assessment of Light-Emitting Diode Parking Structure Lighting at U.S. Department of Labor Headquarters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kinzey, Bruce R.; Myer, Michael

    2013-03-01

    This report documents a solid-state lighting (SSL) technology demonstration at the parking structure of the U.S. Department of Labor (DOL) Headquarters in Washington, DC, in which light-emitting diode (LED) luminaires were substituted for the incumbent high-pressure sodium (HPS) luminaires and evaluated for relative light quantity and performance. The demonstration results show energy savings of 52% from the initial conversion of HPS to the LED product. These savings were increased to 88% by using occupancy sensor controls that were ultimately set to reduce power to 10% of high state operation after a time delay of 2.5 minutes. Because of the relativelymore » high cost of the LED luminaires at their time of purchase for this project (2010), the simple payback periods were 6.5 years and 4.9 years for retrofit and new construction scenarios, respectively. Staff at DOL Headquarters reported high satisfaction with the operation of the LED product.« less

  15. Recent results on output feedback problems

    NASA Technical Reports Server (NTRS)

    Byrnes, C. I.

    1980-01-01

    Given a real linear system sigma = (A, B, C) with m inputs, p outputs and degree n, the problem of generic pole placement by output feedback is studied, which is to compute the constant C(m,p) such that the inequality C(m,p) not less than n is necessary and sufficient for generically positioning the poles of the generic linear system by constant output feedback. A constant C prime (m,p) is determined, which gives a sufficient condition for generic pole placement and which, to the best of the author's knowledge, is at least as good an estimate of C(m,p) as any in the literature. Some results on the construction of solutions in case mp = n are announced, based on the degree formula of Brockett and Byrnes and the Galois theory. In particular, a question raised by Anderson, Bose, and Jury, on the existence of a rational procedure for computing the feedback law from the desired characteristic polynomial is answered.

  16. Numerical analysis of tangential slot blowing on a generic chined forebody

    NASA Technical Reports Server (NTRS)

    Agosta, Roxana M.

    1994-01-01

    A numerical study is performed to investigate the effects of tangential slot blowing on a generic chined forebody. The Reynolds-averaged, thin-layer, Navier-Stokes equations are solved to obtain the high-angle-of-attack viscous flow field about a generic chined forebody. Tangential slot blowing is investigated as a means of forebody flow control to generate side force and yawing moment on the forebody. The effects of jet mass flow ratios, angle of attack, and blowing slot location in the axial and circumferential directions are studied. The computed results are compared with available wind tunnel experimental data. The solutions with and without blowing are also analyzed using helicity density contours, surface flow patterns, and off-surface instantaneous streamlines. The results of this analysis provide details of the flow field about the generic chined forebody, as well as show that tangential slot blowing can be used as a means of forebody flow control to generate side force and yawing moment.

  17. Linearization instability for generic gravity in AdS spacetime

    NASA Astrophysics Data System (ADS)

    Altas, Emel; Tekin, Bayram

    2018-01-01

    In general relativity, perturbation theory about a background solution fails if the background spacetime has a Killing symmetry and a compact spacelike Cauchy surface. This failure, dubbed as linearization instability, shows itself as non-integrability of the perturbative infinitesimal deformation to a finite deformation of the background. Namely, the linearized field equations have spurious solutions which cannot be obtained from the linearization of exact solutions. In practice, one can show the failure of the linear perturbation theory by showing that a certain quadratic (integral) constraint on the linearized solutions is not satisfied. For non-compact Cauchy surfaces, the situation is different and for example, Minkowski space having a non-compact Cauchy surface, is linearization stable. Here we study, the linearization instability in generic metric theories of gravity where Einstein's theory is modified with additional curvature terms. We show that, unlike the case of general relativity, for modified theories even in the non-compact Cauchy surface cases, there are some theories which show linearization instability about their anti-de Sitter backgrounds. Recent D dimensional critical and three dimensional chiral gravity theories are two such examples. This observation sheds light on the paradoxical behavior of vanishing conserved charges (mass, angular momenta) for non-vacuum solutions, such as black holes, in these theories.

  18. Absence of Critical Points of Solutions to the Helmholtz Equation in 3D

    NASA Astrophysics Data System (ADS)

    Alberti, Giovanni S.

    2016-11-01

    The focus of this paper is to show the absence of critical points for the solutions to the Helmholtz equation in a bounded domain {Ωsubset{R}3} , given by { div(a nabla u_{ω}g)-ω qu_{ω}g=0&quad{in Ω,} u_{ω}g=g quad{on partialΩ.} We prove that for an admissible g there exists a finite set of frequencies K in a given interval and an open cover {overline{Ω}=\\cup_{ωin K} Ω_{ω}} such that {|nabla u_{ω}g(x)| > 0} for every {ωin K} and {xinΩ_{ω}} . The set K is explicitly constructed. If the spectrum of this problem is simple, which is true for a generic domain {Ω} , the admissibility condition on g is a generic property.

  19. Computational Investigation of Tangential Slot Blowing on a Generic Chined Forebody

    NASA Technical Reports Server (NTRS)

    Agosta-Greenman, Roxana M.; Gee, Ken; Cummings, Russell M.; Schiff, Lewis B.

    1995-01-01

    The effect of tangential slot blowing on the flowfield about a generic chined forebody at high angles of attack is investigated numerically using solutions of the thin-layer, Reynolds-averaged, Navier-Stokes equations. The effects of jet mass now ratios, angle of attack, and blowing slot location in the axial and circumferential directions are studied. The computed results compare well with available wind-tunnel experimental data. Computational results show that for a given mass now rate, the yawing moments generated by slot blowing increase as the body angle of attack increases. It is observed that greater changes in the yawing moments are produced by a slot located closest to the lip of the nose. Also, computational solutions show that inboard blowing across the top surface is more effective at generating yawing moments than blowing outboard from the bottom surface.

  20. 76 FR 81982 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored information... Administration (ETA), Office of Management and Budget, Room 10235, Washington, DC 20503, Telephone: (202) 395... Insurance statutory and regulatory requirements, ETA 581 provides quarterly data on State agencies' volume...

  1. 76 FR 35472 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Application...

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  2. 48 CFR 2903.101-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... (DOL) hereby announces the submission of the Occupational Safety and Health Administration (OSHA... Officer for the Department of Labor, Occupational Safety and Health Administration (OSHA), Office of... electronic submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Title of...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    Federal Register 2010, 2011, 2012, 2013, 2014

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  7. 77 FR 22805 - Scientific Integrity: Statement of Policy

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... 2009, the President articulated six principles federal agencies should follow to preserve and promote... production of leading economic indicators, evaluation of programs funded by DOL, protection of the health and... principles, we are soliciting public comments. Your input is important to us. To facilitate receipt of the...

  8. 75 FR 82577 - Federal Acquisition Regulation; Payrolls and Basic Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-30

    .... This revision implements a Department of Labor rule that protects the privacy of workers. DATES... of Labor's (DOL's) final rule, Protecting the Privacy of Workers: Labor Standards Provisions... increased risk of privacy violations. The public comment period closed on August 16, 2010. No comments were...

  9. 77 FR 4365 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Vehicle...

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ...: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health... the Department of Labor, Occupational Safety and Health Administration, Office of Management and.... Agency: Occupational Safety and Health Administration. Title of Collection: Vehicle-Mounted Elevating and...

  10. 42 CFR 81.20 - Required use of NIOSH-IREP.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... for estimating probability of causation for covered employees seeking compensation for cancer under EEOICPA, other than as members of the Special Exposure Cohort seeking compensation for a specified cancer. (b) DOL is required to use NIOSH-IREP to estimate probability of causation for all cancers, as...

  11. Building Capacity: Creating Curriculum Pathways

    ERIC Educational Resources Information Center

    Richie, D.

    2016-01-01

    The nation has made an unprecedented investment in community colleges to simultaneously increase college completion and stimulate economic recovery. One of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (U.S. DOL). Beginning October…

  12. 78 FR 67196 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission for OMB Review; Comment Request; Annual Refiling Survey ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Bureau of Labor Statistics (BLS) sponsored information collection request...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission for OMB Review; Comment Request; Regulations Governing the Administration of the Longshore and Harbor Workers' Compensation Act ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Office...

  14. 77 FR 5060 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Bloodborne...

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored..., Occupational Safety and Health Administration (OSHA), Office of Management and Budget, Room 10235, Washington... electronic submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Title of...

  15. 77 FR 5278 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Commercial...

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored..., Occupational Safety and Health Administration (OSHA), Office of Management and Budget, Room 10235, Washington... submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Title of Collection...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    ..., Occupational Safety and Health Administration (OSHA), Office of Management and Budget, Room 10235, Washington... Department of Labor (DOL) hereby announces the submission of the Occupational Safety and Health... Health Administration (OSHA). Type of Review: Extension without change of currently approved collection...

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  18. 75 FR 67768 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Baseline...

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Type of Review: New...: The Department of Labor (DOL) hereby announces submission of the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR), ``Baseline Safety and Health Practices...

  19. 78 FR 16538 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Standard on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    .... SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled, ``Standard on 4,4'-Methylenedianiline in...'-Methylenedianiline (MDA) in Construction protects workers from adverse health effects associated with occupational...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Title of Collection...: The Department of Labor (DOL) hereby announces the submission of the Occupational Safety and Health... Health Administration (OSHA), Office of Management and Budget, Room 10235, Washington, DC 20503...

  1. 75 FR 81660 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Logging...

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    ..., Attn: OMB Desk Officer for the Department of Labor, Occupational Safety and Health Administration (OSHA...., permitting electronic submission of responses. Agency: Occupational Safety and Health Administration (OSHA... of Labor (DOL) hereby announces the submission of the Occupational Safety and Health Administration...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... electronic submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Title of... Department of Labor (DOL) hereby announces the submission of the Occupational Safety and Health... Health Administration (OSHA), Office of Management and Budget, Room 10235, Washington, DC 20503...

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  7. 48 CFR 2917.504-70 - Signature authority and internal procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... The Economy Act 2917.504-70 Signature authority and internal procedures. (a) A DOL contracting officer, HCA, Agency Head, or another official designated by the Assistant Secretary for Administration and... the signing of all new Federal Interagency Agreements and deleting expired agreements. (c) Agencies...

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    2010-11-30

    ... for OMB Review; Comment Request; Job Corps Enrollee Allotment Determination ACTION: Notice. SUMMARY: The Department of Labor (DOL) hereby announces the submission of the Employment and Training Administration (ETA) sponsored information collection request (ICR) titled, ``Job Corps Enrollee Allotment...

  10. 42 CFR 81.20 - Required use of NIOSH-IREP.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... for estimating probability of causation for covered employees seeking compensation for cancer under EEOICPA, other than as members of the Special Exposure Cohort seeking compensation for a specified cancer. (b) DOL is required to use NIOSH-IREP to estimate probability of causation for all cancers, as...

  11. 42 CFR 81.20 - Required use of NIOSH-IREP.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... for estimating probability of causation for covered employees seeking compensation for cancer under EEOICPA, other than as members of the Special Exposure Cohort seeking compensation for a specified cancer. (b) DOL is required to use NIOSH-IREP to estimate probability of causation for all cancers, as...

  12. 42 CFR 81.20 - Required use of NIOSH-IREP.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... for estimating probability of causation for covered employees seeking compensation for cancer under EEOICPA, other than as members of the Special Exposure Cohort seeking compensation for a specified cancer. (b) DOL is required to use NIOSH-IREP to estimate probability of causation for all cancers, as...

  13. 48 CFR 2901.603-70 - Responsibility of other government personnel.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... buying process, and execution of the contract rests with the contracting officer. (b) Personnel... obligation. However, DOL personnel who must use the contracting process to accomplish their programs must... and open competition are satisfied to the maximum extent practicable. Sole source purchases may only...

  14. Geochronology, geochemistry and isotope tracing of the Oligocene magmatism of the Buchim-Damjan-Borov Dol ore district: Implications for timing, duration and source of the magmatism

    NASA Astrophysics Data System (ADS)

    Lehmann, St.; Barcikowski, J.; von Quadt, A.; Gallhofer, D.; Peytcheva, I.; Heinrich, C. A.; Serafimovski, T.

    2013-11-01

    Timing, source and magmatic evolution of the intrusions in the Buchim-Damjan-Borov Dol ore district of the Former Yugoslav Republic of Macedonia (F.Y.R.O.M.) have been studied. They intrude the Circum Rhodope Unit close to the contact with the Vardar Zone and are a part of the Late Eocene-Oligocene Macedonian Rhodope-North Aegean belt. The magmatism at Buchim-Damjan-Borov Dol occurred between 24.04 ± 0.77 and 24.51 ± 0.89 Ma, as indicated by chemical-annealing (CA)-LA ICP-MS zircon dating. Major element, trace and rare earth element analyses have been performed on the various intrusive rocks. All ore bearing magmas were classified as trachyandesitic, except the youngest intrusion which is not associated with mineralization; the Black Hill locality (24.04 ± 0.77 Ma) shows a trachytic composition. The distribution of the trace elements, enrichment of large ion lithophile elements (LILE) and depletion in high field strength elements (HFSE), indicates subduction-related magmatism; most of the magmas follow a calc-alkaline fractionation trend with shoshonitic affinities; additionally, Sr/Y (10 to 90) and La/Yb values show some similarities to adakite-like magmas. Sr and Nd isotope ratios (Sri = 0.70658 to 0.70740 and Ndi = 0.512425-0.512497) show that the magmatic products were slightly contaminated by continental crust material, e.g., the Variscan/Cadomian basement. In the Late Eocene-Oligocene belt the magmatism between 29 and 35 Ma is dominated by crustal melting with an increase in the mantle contribution between 20 and 27 Ma. We suggest the following scenario for the magmatic history of the Buchim-Damjan-Borov Dol ore district: a slab rollback of an oceanic slab located further to the SW which led to extensional and compressional features in upper levels of the continental crust. In the middle to upper crust three consecutive crystallization stages occurred at variable depths as indicated by amphibole zonation. Mixing of newly formed crust with mantle-like affinities and continental crust material in variable degrees during the ascent of the magma can explain all geochemical characteristics. The magma crystallized as dykes or stocks near the Earth's surface (> 1 km) after its final emplacement and contemporaneous hydrothermal activity led to different mineralization styles depending on the lithology of the host rocks.

  15. N-terminal pro-brain natriuretic peptide as a useful predictor of early surgery in neonates with congenital heart diseases: a prospective observational study.

    PubMed

    Makimura, Mika; Koga, Hiroshi

    2014-01-01

    Pediatric studies have found a correlation between the clinical heart failure score and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels. However, the clinical usefulness of this marker remains unclear in neonates. At hospitals without pediatric cardiologists, neonatologists or general pediatricians must judge whether surgery is indicated and transfer patients to a specialized hospital in a timely fashion as required. Thus, we tested the hypothesis that increased NT-proBNP levels predict short-term outcomes in neonates with congenital heart diseases (CHDs) and are thus a useful tool for evaluating clinical status and guiding treatment. Subjects were term or near-term newborns (≥36 weeks' gestation) with CHDs confined to left-to-right shunt lesions. Clinical parameters and NT-proBNP levels were measured on the first 7, 14, 21, and 28 days of life (DOL). We divided patients into a surgical (n = 7) and a conservative-treatment group (n = 21), and then compared clinical variables and outcomes between the groups. In the surgical group, NT-proBNP levels had a tendency to increase during the first 14 postnatal days and were significantly greater than in the conservative-treatment group on 7 DOL [median (range), 13,983 pg/mL (4,732-26,524) vs. 1,954 pg/mL (671-10,881); p = 0.0028] and on 14 DOL [29,274 pg/mL (14,006-33,740) vs. 2,050 pg/mL (1,304-9,250); p = 0.0055]. In contrast, NT-proBNP levels tended to decrease sequentially in the conservative-treatment group. The values of additional markers, such as mean NT-proBNP level on 7 and 14 DOLs (M7-14) and NT-proBNP level on 14 DOL minus that on 7 DOL (Δ7-14), were both significantly greater in the surgical group than in the conservative-treatment group. To examine the usability of M7-14 and Δ7-14 when the difference and mean cut-off levels were set at 10,000 and 3,000 pg/mL, respectively, the sensitivity and specificity were both 100 %. In neonates who had CHDs with left-to-right shunt, analysis of the association between clinical variables and short-term outcomes showed that NT-proBNP, especially M7-14 and Δ7-14, is a useful predictor of early surgery.

  16. Holistic Context-Sensitivity for Run-Time Optimization of Flexible Manufacturing Systems.

    PubMed

    Scholze, Sebastian; Barata, Jose; Stokic, Dragan

    2017-02-24

    Highly flexible manufacturing systems require continuous run-time (self-) optimization of processes with respect to diverse parameters, e.g., efficiency, availability, energy consumption etc. A promising approach for achieving (self-) optimization in manufacturing systems is the usage of the context sensitivity approach based on data streaming from high amount of sensors and other data sources. Cyber-physical systems play an important role as sources of information to achieve context sensitivity. Cyber-physical systems can be seen as complex intelligent sensors providing data needed to identify the current context under which the manufacturing system is operating. In this paper, it is demonstrated how context sensitivity can be used to realize a holistic solution for (self-) optimization of discrete flexible manufacturing systems, by making use of cyber-physical systems integrated in manufacturing systems/processes. A generic approach for context sensitivity, based on self-learning algorithms, is proposed aiming at a various manufacturing systems. The new solution encompasses run-time context extractor and optimizer. Based on the self-learning module both context extraction and optimizer are continuously learning and improving their performance. The solution is following Service Oriented Architecture principles. The generic solution is developed and then applied to two very different manufacturing processes.

  17. Holistic Context-Sensitivity for Run-Time Optimization of Flexible Manufacturing Systems

    PubMed Central

    Scholze, Sebastian; Barata, Jose; Stokic, Dragan

    2017-01-01

    Highly flexible manufacturing systems require continuous run-time (self-) optimization of processes with respect to diverse parameters, e.g., efficiency, availability, energy consumption etc. A promising approach for achieving (self-) optimization in manufacturing systems is the usage of the context sensitivity approach based on data streaming from high amount of sensors and other data sources. Cyber-physical systems play an important role as sources of information to achieve context sensitivity. Cyber-physical systems can be seen as complex intelligent sensors providing data needed to identify the current context under which the manufacturing system is operating. In this paper, it is demonstrated how context sensitivity can be used to realize a holistic solution for (self-) optimization of discrete flexible manufacturing systems, by making use of cyber-physical systems integrated in manufacturing systems/processes. A generic approach for context sensitivity, based on self-learning algorithms, is proposed aiming at a various manufacturing systems. The new solution encompasses run-time context extractor and optimizer. Based on the self-learning module both context extraction and optimizer are continuously learning and improving their performance. The solution is following Service Oriented Architecture principles. The generic solution is developed and then applied to two very different manufacturing processes. PMID:28245564

  18. Evasion of No-Hair Theorems and Novel Black-Hole Solutions in Gauss-Bonnet Theories

    NASA Astrophysics Data System (ADS)

    Antoniou, G.; Bakopoulos, A.; Kanti, P.

    2018-03-01

    We consider a general Einstein-scalar-Gauss-Bonnet theory with a coupling function f (ϕ ) . We demonstrate that black-hole solutions appear as a generic feature of this theory since a regular horizon and an asymptotically flat solution may be easily constructed under mild assumptions for f (ϕ ). We show that the existing no-hair theorems are easily evaded, and a large number of regular black-hole solutions with scalar hair are then presented for a plethora of coupling functions f (ϕ ).

  19. Evasion of No-Hair Theorems and Novel Black-Hole Solutions in Gauss-Bonnet Theories.

    PubMed

    Antoniou, G; Bakopoulos, A; Kanti, P

    2018-03-30

    We consider a general Einstein-scalar-Gauss-Bonnet theory with a coupling function f(ϕ). We demonstrate that black-hole solutions appear as a generic feature of this theory since a regular horizon and an asymptotically flat solution may be easily constructed under mild assumptions for f(ϕ). We show that the existing no-hair theorems are easily evaded, and a large number of regular black-hole solutions with scalar hair are then presented for a plethora of coupling functions f(ϕ).

  20. Selective Transfer Machine for Personalized Facial Action Unit Detection

    PubMed Central

    Chu, Wen-Sheng; De la Torre, Fernando; Cohn, Jeffery F.

    2014-01-01

    Automatic facial action unit (AFA) detection from video is a long-standing problem in facial expression analysis. Most approaches emphasize choices of features and classifiers. They neglect individual differences in target persons. People vary markedly in facial morphology (e.g., heavy versus delicate brows, smooth versus deeply etched wrinkles) and behavior. Individual differences can dramatically influence how well generic classifiers generalize to previously unseen persons. While a possible solution would be to train person-specific classifiers, that often is neither feasible nor theoretically compelling. The alternative that we propose is to personalize a generic classifier in an unsupervised manner (no additional labels for the test subjects are required). We introduce a transductive learning method, which we refer to Selective Transfer Machine (STM), to personalize a generic classifier by attenuating person-specific biases. STM achieves this effect by simultaneously learning a classifier and re-weighting the training samples that are most relevant to the test subject. To evaluate the effectiveness of STM, we compared STM to generic classifiers and to cross-domain learning methods in three major databases: CK+ [20], GEMEP-FERA [32] and RU-FACS [2]. STM outperformed generic classifiers in all. PMID:25242877

  1. Generic evolution of mixing in heterogeneous media

    NASA Astrophysics Data System (ADS)

    De Dreuzy, J.; Carrera, J.; Dentz, M.; Le Borgne, T.

    2011-12-01

    Mixing in heterogeneous media results from the competition bewteen flow fluctuations and local scale diffusion. Flow fluctuations quickly create concentration contrasts and thus heterogeneity of the concentration field, which is slowly homogenized by local scale diffusion. Mixing first deviates from Gaussian mixing, which represents the potential mixing induced by spreading before approaching it. This deviation fundamentally expresses the evolution of the interaction between spreading and local scale diffusion. We characterize it by the ratio γ of the non-Gaussian to the Gaussian mixing states. We define the Gaussian mixing state as the integrated squared concentration of the Gaussian plume that has the same longitudinal dispersion as the real plume. The non-Gaussian mixing state is the difference between the overall mixing state defined as the integrated squared concentration and the Gaussian mixing state. The main advantage of this definition is to use the full knowledge previously acquired on dispersion for characterizing mixing even when the solute concentration field is highly non Gaussian. Using high precision numerical simulations, we show that γ quickly increases, peaks and slowly decreases. γ can be derived from two scales characterizing spreading and local mixing, at least for large flux-weighted solute injection conditions into classically log-normal Gaussian correlated permeability fields. The spreading scale is directly related to the longitudinal dispersion. The local mixing scale is the largest scale over which solute concentrations can be considered locally uniform. More generally, beyond the characteristics of its maximum, γ turns out to have a highly generic scaling form. Its fast increase and slow decrease depend neither on the heterogeneity level, nor on the ratio of diffusion to advection, nor on the injection conditions. They might even not depend on the particularities of the flow fields as the same generic features also prevail for Taylor dispersion. This generic characterization of mixing can offer new ways to set up transport equations that honor not only advection and spreading (dispersion), but also mixing.

  2. 76 FR 44979 - Section 5309 Discretionary Bus and Bus Facilities Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    .... The Department of Labor (DOL) will make social communication technologies and training available to... veterans and military service families. This announcement is available on the FTA's Web site, on the Veterans Transportation and Community Living initiative Web page at: http://www.fta.dot.gov/veterans . FTA...

  3. 29 CFR 71.15 - Training.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Training. 71.15 Section 71.15 Labor Office of the Secretary... § 71.15 Training. All DOL systems managers, disclosure officers, and employees with responsibilities under the Privacy Act shall periodically attend training offered by the Department on the Privacy Act. ...

  4. 76 FR 17153 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-28

    ... for OMB Review; Comment Request; Proposed Evaluation of the Aging Worker Initiative Grants ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the proposed Employment and Training [[Page... Aging Worker Initiative Grants,'' to the Office of Management and Budget (OMB) for review and approval...

  5. 76 FR 44047 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Workforce...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... of Labor (DOL) is submitting the revised Employment and Training Administration (ETA) sponsored... Training Administration (ETA), Office of Management and Budget, Room 10235, Washington, DC 20503, Telephone... Investment Act Title I programs. Applications are submitted to the ETA National Office on behalf of states...

  6. 78 FR 68096 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Quick...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-13

    ... Training Administration (ETA) sponsored information collection request (ICR) titled, ``Quick Turnaround... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL- ETA, Office of Management and Budget, Room... authority for the ETA to conduct quick turnaround surveys on Workforce Investment Act (WIA) related issues...

  7. 78 FR 50448 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Income and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ... (ETA) sponsored information collection request (ICR) titled, ``Income and Eligibility Verification... this request to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA..., the ETA issued a final rule regarding the Confidentiality and Disclosure of State Unemployment...

  8. 78 FR 6132 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Petition...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... and Training Administration (ETA) sponsored information collection request (ICR) revision titled... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room... certification of eligibility to apply for adjustment assistance. Versions of Form ETA-9042, Petition for Trade...

  9. 78 FR 68864 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Veterans...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-15

    ... (ETA) sponsored information collection request (ICR) titled, ``Veterans Retraining Assistance... Officer for DOL- ETA, Office of Management and Budget, Room 10235, 725 17th Street NW., Washington, DC...(a)(1)(D). SUPPLEMENTARY INFORMATION: This ICR seeks continued PRA authorization for the ETA to...

  10. 78 FR 68095 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; American...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-13

    ...) is submitting the Employment and Training Administration (ETA) sponsored information collection... Officer for DOL-ETA, Office of Management and Budget, Room 10235, 725 17th Street NW., Washington, DC... INFORMATION: The ICR seeks continued PRA authorization for the ETA to conduct the American Recovery and...

  11. 78 FR 76656 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-18

    ... to provide the OSHA, National Institute for Occupational Safety and Health, affected workers, and... Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information... Occupational Safety and Health Act authorizes this information collection. See 29 U.S.C. 651, 655, and 657...

  12. 76 FR 32988 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Grain...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information..., Occupational Safety and Health Administration (OSHA), Office of Management and Budget, Room 10235, Washington... directed toward assuring the safety of workers in grain handling through development of a housekeeping plan...

  13. 78 FR 36276 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Regulations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... Complaints ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) revision titled... Budget (OMB) for review and approval for use in accordance with the Paperwork Reduction Act (PRA) of 1995...

  14. 76 FR 5402 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Standard on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... (DOL) hereby announces the submission of the Occupational Safety and Health Administration (OSHA..., Attn: OMB Desk Officer for the Department of Labor, Occupational Safety and Health Administration (OSHA... electronic submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Title of...

  15. 78 FR 13897 - Final Revision and Publication of the 2012 Form M-1, Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-01

    ... DEPARTMENT OF LABOR Employee Benefits Security Administration RIN 1210-AB51 Final Revision and Publication of the 2012 Form M-1, Notice AGENCY: Employee Benefits Security Administration, Department of... Security Administration's (EBSA) Web site at www.dol.gov/ebsa . The revised form is substantively different...

  16. 77 FR 38322 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Training...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... Department of Labor (DOL) is submitting the Mine Safety and Health Administration sponsored information... significant safety regulations affecting this industry sector. Training informs miners of safety and health... production demands; and increased demand for contractors who may be less familiar with the dangers on mine...

  17. 77 FR 36576 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission for OMB Review; Comment Request; Notice of Termination, Suspension, Reduction, or Increase in Benefit Payments ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Office of Workers...

  18. 29 CFR 42.5 - Policy review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... policies of OSHA, ESA and the United States Employment Service (USES), and the Office of the Solicitor and... complaints under, and to detect promptly violations of, any of the protective statutes. (2) The expedited... State agency of violations or complaints discovered by or reported to DOL agencies or appropriate State...

  19. 77 FR 67834 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ... for OMB Review; Comment Request; Health Insurance Claim Form ACTION: Notice. SUMMARY: The Department... information collection request (ICR) revision titled, ``Health Insurance Claim Form,'' (Form OWCP-1500) to the... submission of responses. Agency: DOL-OWCP. Title of Collection: Health Insurance Claim Form. OMB Control...

  20. 42 CFR 81.22 - General guidelines for use of NIOSH-IREP.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES GUIDELINES FOR DETERMINING PROBABILITY OF CAUSATION... Probability of Causation § 81.22 General guidelines for use of NIOSH-IREP. DOL will use procedures specified in the NIOSH-IREP Operating Guide to calculate probability of causation estimates under EEOICPA. The...

  1. Gateway's Horizon: A Center of Excellence

    ERIC Educational Resources Information Center

    Herring, Jayne; Colony, Lee

    2007-01-01

    This article describes Gateway Technical College's Horizon Center for Transportation Technology, located in Kenosha, Wisconsin, which was the product of collaboration with business and industry, community support and a U.S. Department of Labor (DOL) grant. The center, which opened this fall, is a prime example of a sustainable community…

  2. 48 CFR 22.805 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... National Preaward Registry via the Internet at http://www.dol-esa.gov/preaward/; (ii) The projected award date is within 24 months of the proposed contractor's Notice of Compliance completion date in the... the OFCCP regional office at least 30 days before the proposed award date. (7) Within 15 days of the...

  3. 75 FR 5499 - Claims for Compensation; Death Gratuity Under the Federal Employees' Compensation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ... for Compensation; Death Gratuity Under the Federal Employees' Compensation Act AGENCY: Office of... Labor (DOL) published an interim final rule in order to administer the death gratuity created by section... provides a death gratuity payment to eligible survivors of federal employees and non-appropriated fund...

  4. 78 FR 7457 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... request (ICR) titled, ``International Training Application,'' to the Office of Management and Budget (OMB... for OMB Review; Comment Request; International Training Application ACTION: Notice. SUMMARY: The... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-BLS, Office of Management and Budget, Room...

  5. 75 FR 61177 - Agency Information Collection Activities; Submission for OMB Review; Comment Request for Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... Federal Employees' Compensation Act ACTION: Notice. SUMMARY: The Department of Labor (DOL) hereby... Workers' Compensation Programs titled, ``Contractor Survey under Federal Employees' Compensation Act,'' to the Office of Management and Budget (OMB) for review and approval in accordance with the Paperwork...

  6. 42 CFR 82.27 - How can claimants obtain reviews of their NIOSH dose reconstruction results by NIOSH?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES METHODS FOR CONDUCTING DOSE RECONSTRUCTION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION..., the methods employed in the review, and the review findings to the claimant, DOL, and DOE. ...

  7. 48 CFR 522.804-2 - Construction.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Construction. 522.804-2... Construction. Goals for the employment of minorities and women in the construction industry are established by... Construction Contractors.” This guide can be accessed at http://www.dol.gov/esa/ofccp/TAguides/ctaguide.htm...

  8. 48 CFR 522.804-2 - Construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Construction. 522.804-2... Construction. Goals for the employment of minorities and women in the construction industry are established by... Construction Contractors.” This guide can be accessed at http://www.dol.gov/esa/ofccp/TAguides/ctaguide.htm...

  9. 48 CFR 522.804-2 - Construction.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Construction. 522.804-2... Construction. Goals for the employment of minorities and women in the construction industry are established by... Construction Contractors.” This guide can be accessed at http://www.dol.gov/esa/ofccp/TAguides/ctaguide.htm...

  10. 48 CFR 522.804-2 - Construction.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Construction. 522.804-2... Construction. Goals for the employment of minorities and women in the construction industry are established by... Construction Contractors.” This guide can be accessed at http://www.dol.gov/esa/ofccp/TAguides/ctaguide.htm...

  11. 48 CFR 522.804-2 - Construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Construction. 522.804-2... Construction. Goals for the employment of minorities and women in the construction industry are established by... Construction Contractors.” This guide can be accessed at http://www.dol.gov/esa/ofccp/TAguides/ctaguide.htm...

  12. 77 FR 73683 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Escape and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-11

    ... for OMB Review; Comment Request; Escape and Evacuation Plans for Surface Coal Mines and Surface Facilities and Surface Work Areas of Underground Coal Mines ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Mine safety and Health Administration (MSHA) sponsored information collection...

  13. 77 FR 37440 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Mine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... for OMB Review; Comment Request; Mine Mapping and Records of Opening, Closing, and Reopening of Mines ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Mine Safety and Health Administration (MSHA) sponsored information collection request (ICR) titled, ``Mine Mapping and Records of...

  14. 20 CFR 655.1317 - Revocation of approved labor certifications.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... revocation under § 655.117(a), the CO will notify the employer, by means normally ensuring next-day delivery... labor certifications. (a) Basis for DOL revocation. The CO, in consultation with the Administrator, OFLC... CO finds that issuance of the temporary agricultural labor certification was not justified due to a...

  15. 20 CFR 655.164 - Denied certification.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... means normally assuring next-day delivery and a copy, if appropriate, to the employer's agent or... (fax), or other means normally assuring next day delivery, a written request to the Chief ALJ of DOL (giving the address) and simultaneously serve a copy on the CO. The notice will also state that the...

  16. 20 CFR 655.164 - Denied certification.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... means normally assuring next-day delivery and a copy, if appropriate, to the employer's agent or... (fax), or other means normally assuring next day delivery, a written request to the Chief ALJ of DOL (giving the address) and simultaneously serve a copy on the CO. The notice will also state that the...

  17. 20 CFR 655.1317 - Revocation of approved labor certifications.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... revocation under § 655.117(a), the CO will notify the employer, by means normally ensuring next-day delivery... labor certifications. (a) Basis for DOL revocation. The CO, in consultation with the Administrator, OFLC... CO finds that issuance of the temporary agricultural labor certification was not justified due to a...

  18. Building Capacity: Expanding Student Support Services

    ERIC Educational Resources Information Center

    Kirby, C. L.

    2016-01-01

    The nation has made an unprecedented investment in community colleges to simultaneously increase college completion and stimulate economic recovery. One of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (U.S.DOL). Beginning October 2011,…

  19. Building Capacity: Creating and Leveraging Partnerships

    ERIC Educational Resources Information Center

    Richie, D.

    2016-01-01

    The nation has made an unprecedented investment in community colleges to simultaneously increase college completion and stimulate economic recovery. One of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (U.S.DOL). Beginning October 2011,…

  20. 75 FR 57062 - Proposed Collection of Information; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... procedures. The delegation includes specific terms and conditions and is subject to the terms and conditions set forth in the ``Standard Operating Procedures for Delegated Government-Owned Real Property'' ``SOP... Administration and Management (OASAM) operates the FPB under a 2003 delegation from GSA; the existing GSA-DOL...

  1. 78 FR 8022 - Reorganization and Delegation of Authority; Technical Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... 20210, olms-public@dol.gov , (202) 693-0123 (this is not a toll-free number), (800) 877-8339 (TTY/TDD... administrative enforcement framework. Further, Secretary's Order No. 02-2012, 77 FR 69378, also delegated... of agency organization, procedure, or practice'' from proposed rulemaking (i.e., notice-and-comment...

  2. 29 CFR 71.15 - Training.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Training. 71.15 Section 71.15 Labor Office of the Secretary of Labor PROTECTION OF INDIVIDUAL PRIVACY AND ACCESS TO RECORDS UNDER THE PRIVACY ACT OF 1974 General § 71.15 Training. All DOL systems managers, disclosure officers, and employees with responsibilities...

  3. 29 CFR 71.15 - Training.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Training. 71.15 Section 71.15 Labor Office of the Secretary of Labor PROTECTION OF INDIVIDUAL PRIVACY AND ACCESS TO RECORDS UNDER THE PRIVACY ACT OF 1974 General § 71.15 Training. All DOL systems managers, disclosure officers, and employees with responsibilities...

  4. 29 CFR 71.15 - Training.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Training. 71.15 Section 71.15 Labor Office of the Secretary of Labor PROTECTION OF INDIVIDUAL PRIVACY AND ACCESS TO RECORDS UNDER THE PRIVACY ACT OF 1974 General § 71.15 Training. All DOL systems managers, disclosure officers, and employees with responsibilities...

  5. 29 CFR 71.15 - Training.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Training. 71.15 Section 71.15 Labor Office of the Secretary of Labor PROTECTION OF INDIVIDUAL PRIVACY AND ACCESS TO RECORDS UNDER THE PRIVACY ACT OF 1974 General § 71.15 Training. All DOL systems managers, disclosure officers, and employees with responsibilities...

  6. 76 FR 81983 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Cognitive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... Statistics (BLS). Title of Collection: Cognitive and Psychological Research. OMB Control Number: 1220-0141... Department of Labor (DOL) is submitting the Bureau of Labor Statistics (BLS) sponsored information collection... Statistics (BLS), Office of Management and Budget, Room 10235, Washington, DC 20503, Telephone: (202) 395...

  7. 78 FR 31579 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Petition...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... for OMB Review; Comment Request; Petition for Finding Under Employee Retirement Income Security Act ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Employee Benefits Security... Employee Retirement Income Security Act Section 3(40),'' to the Office of Management and Budget (OMB) for...

  8. 77 FR 37954 - Revision of Form FHWA-1273

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-25

    ... inclusion in contract requirements between the New Jersey DOT and the contractor. FHWA Response: Form FHWA... Comments by Section Section I. General The Wyoming DOT recommended that FHWA either mandate the inclusion... social security numbers in Section IV.3. FHWA Response 2: On December 19, 2008, DOL issued a final rule...

  9. 78 FR 77497 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-23

    ... Training Requirements ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled... Occupational Safety and Health Act authorizes this information collection. See 29 U.S.C. 651 and 657. This...

  10. 76 FR 67225 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Standard on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information... Regulatory Affairs, Attn: OMB Desk Officer for the Department of Labor, Occupational Safety and Health... Health Administration (OSHA). Title of Collection: Standard on Slings. OMB Control Number: 1218-0223...

  11. 77 FR 5277 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ..., Attn: OMB Desk Officer for the Department of Labor, Occupational Safety and Health Administration (OSHA... submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Title of Collection... ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health...

  12. 76 FR 5613 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Storage and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-01

    ...: The Department of Labor (DOL) hereby announces the submission of the Occupational Safety and Health... Health Administration (OSHA), Office of Management and Budget, Room 10235, Washington, DC 20503... Health Administration (OSHA). Title of Collection: Storage and Handling of Anhydrous Ammonia. OMB Control...

  13. 76 FR 45297 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Design of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-28

    ... Department of Labor, Occupational Safety and Health Administration (OSHA), Office of Management and Budget... submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Title of Collection.... SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration...

  14. 78 FR 78386 - Agency Information Collection Activities; Submission for OMB Review; Comment Request: Definition...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) revision... NRTL Program. The Occupational Safety and Health Act authorizes the information collection provisions... Desk Officer for DOL- OSHA, Office of Management and Budget, Room 10235, 725 17th Street NW...

  15. 78 FR 77496 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Student...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-23

    ... (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information... maintain PRA authorization for the Student Data Form, Form OSHA-182. The Occupational Safety and Health Act... education in occupational safety and health for Federal and State compliance officers, OSHA professionals...

  16. 78 FR 23785 - Agency Information Collection Activities; Submission for OMB Review; Comment Request: Standard on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-22

    ...: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled, ``Standard on 4,4...-OSHA, Office of Management and Budget, Room 10235, 725 17th Street NW., Washington, DC 20503, Fax: 202...

  17. 75 FR 81662 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Affordable...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    .... SUMMARY: The Department of Labor (DOL) hereby announces the submission of the Employee Benefits Security... coverage for group health plans and health insurance issuers offering group or individual health insurance... health insurance issuer offering group or individual health insurance coverage generally must not rescind...

  18. Presentation at DOL [Department of Labor] Conference on Aging.

    ERIC Educational Resources Information Center

    St. John, A. P.

    This document addresses the issue of the aging American workforce by describing the current demographics of the Chrysler Corporation workforce, reviewing Chrysler's future projections, and discussing some of the changes being implemented by Chrysler to accommodate the aging Chrysler active and retiree population. It compares average ages of hourly…

  19. 75 FR 62571 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; American...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission... Industries Grants Information Collection ACTION: Notice. SUMMARY: The Department of Labor (DOL) hereby...), Public Law 104-13, 44 U.S.C. chapter 35. DATES: Submit comments on or before November 12, 2010. ADDRESSES...

  20. 29 CFR 95.33 - Federally-owned and exempt property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... in accordance with E.O. 12821, “Improving Mathematics and Science Education in Support of the National Education Goals.”) Appropriate instructions shall be issued to the recipient by DOL. (b) Exempt... Labor Office of the Secretary of Labor GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION...

  1. 29 CFR 95.33 - Federally-owned and exempt property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... in accordance with E.O. 12821, “Improving Mathematics and Science Education in Support of the National Education Goals.”) Appropriate instructions shall be issued to the recipient by DOL. (b) Exempt... Labor Office of the Secretary of Labor GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION...

  2. 29 CFR 95.33 - Federally-owned and exempt property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... in accordance with E.O. 12821, “Improving Mathematics and Science Education in Support of the National Education Goals.”) Appropriate instructions shall be issued to the recipient by DOL. (b) Exempt... Labor Office of the Secretary of Labor GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION...

  3. 29 CFR 95.33 - Federally-owned and exempt property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... in accordance with E.O. 12821, “Improving Mathematics and Science Education in Support of the National Education Goals.”) Appropriate instructions shall be issued to the recipient by DOL. (b) Exempt... Labor Office of the Secretary of Labor GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION...

  4. 29 CFR 95.33 - Federally-owned and exempt property.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... in accordance with E.O. 12821, “Improving Mathematics and Science Education in Support of the National Education Goals.”) Appropriate instructions shall be issued to the recipient by DOL. (b) Exempt... Labor Office of the Secretary of Labor GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION...

  5. 78 FR 64536 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Claim for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-29

    ... the War Hazards Compensation Act ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission...) revision titled, ``Claim for Reimbursement of Benefit Payments and Claims Expense under the War Hazards...

  6. 77 FR 71196 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Jobs for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-29

    ... for OMB Review; Comment Request; Jobs for Veterans State Grants Reports ACTION: Notice. SUMMARY: On November 30, 2012, the Department of Labor (DOL) will submit the Veterans' Employment and Training Service (VETS) sponsored information collection request (ICR) revision titled, ``Jobs for Veterans State Grants...

  7. 75 FR 74082 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Job Corps...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... obtain information about student training for placement of students in jobs, further education or... for OMB Review; Comment Request; Job Corps Placement and Assistance Record ACTION: Notice. SUMMARY: The Department of Labor (DOL) hereby announces the submission of the Employment and Training...

  8. 78 FR 67198 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Job Corps...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... for OMB Review; Comment Request; Job Corps Application Data ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored information collection request (ICR) titled, ``Job Corps Application Data,'' to the Office of Management and Budget (OMB...

  9. 78 FR 13383 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Standard...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

    ... for OMB Review; Comment Request; Standard Job Corps Contractor Information Gathering ACTION: Notice... Contractor Information Gathering,'' to the Office of Management and Budget (OMB) for review and approval for... submission of responses. Agency: DOL-ETA. Title of Collection: Standard Job Corps Contractor Information...

  10. 76 FR 82321 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... for OMB Review; Comment Request; Notice of Controversion of Right to Compensation ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Office of Workers' Compensation Programs (OWCP) sponsored information collection request (ICR) titled, Notice of Controversion of Right to Compensation...

  11. 76 FR 44960 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Report on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... for OMB Review; Comment Request; Report on Current Employment Statistics ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the revised Bureau of Labor Statistics (BLS) sponsored information collection request (ICR) titled, ``Report on Current Employment Statistics,'' to the Office of Management and...

  12. Does GastroPlus Support Similarity and Dissimilarity Factors of in vitro-in vivo Prediction in Biowaiver Studies? A Lower Strength Amlodipine As a Model Drug.

    PubMed

    Naser Zaid, Abdel; Shraim, Naser; Radwan, Asmaa; Jaradat, Nidal; Hirzallah, Samah; Issa, Ibrahim; Khraim, Aya

    2018-05-23

    Many generic pharmaceutical products are currently available on the market place worldwide. Recently, there is a growing concern on the quality and efficacy of generic products. However, health care professionals such as physicians and pharmacists are in difficult situations to choose among alternatives. The aim of this study is to assess the effectiveness of the in silico technique (Gastro Plus ® ) in the biowaiver study and whether similarity and dissimilarity factors ( f 2 and f 1 respectively) are effective in this regard. The concentration of amlodipine in the sample was calculated by comparing the absorbance of the sample with that of a previously prepared amlodipine standard solution using validated HPLC method. The dissolution profile for each product (brand and generics) was constructed. The similarity ( f2) and dissimilarity ( f 1 ) factors were calculated for the generic product according to equation 1 and 2. GastroPlus™ software (version 9.0, Simulations Plus Inc., Lancaster, CA, USA) was used to predict the absorption profiles of amlodipine from the generic product Amlovasc ® and the reference Norvasc ® . These results may provide a rationale for the interchangeability between the RLD and generic version based on in vitro release profiles in silico technique especially in a lower strength dose drug. © Georg Thieme Verlag KG Stuttgart · New York.

  13. Determination of an Optimal Control Strategy for a Generic Surface Vehicle

    DTIC Science & Technology

    2014-06-18

    paragraphs uses the numerical procedure in MATLAB’s BVP (bvp4c) algorithm using the continuation method. The goal is to find a solution to the set of...solution. Solving the BVP problem using bvp4c requires an initial guess for the solution. Note that the algorithm is very sensitive to the particular...form of the initial guess. The quality of the initial guess is paramount in convergence speed of the BVP algorithm and often determines if the

  14. Parallel artificial liquid membrane extraction as an efficient tool for removal of phospholipids from human plasma.

    PubMed

    Ask, Kristine Skoglund; Bardakci, Turgay; Parmer, Marthe Petrine; Halvorsen, Trine Grønhaug; Øiestad, Elisabeth Leere; Pedersen-Bjergaard, Stig; Gjelstad, Astrid

    2016-09-10

    Generic Parallel Artificial Liquid Membrane Extraction (PALME) methods for non-polar basic and non-polar acidic drugs from human plasma were investigated with respect to phospholipid removal. In both cases, extractions in 96-well format were performed from plasma (125μL), through 4μL organic solvent used as supported liquid membranes (SLMs), and into 50μL aqueous acceptor solutions. The acceptor solutions were subsequently analysed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) using in-source fragmentation and monitoring the m/z 184→184 transition for investigation of phosphatidylcholines (PC), sphingomyelins (SM), and lysophosphatidylcholines (Lyso-PC). In both generic methods, no phospholipids were detected in the acceptor solutions. Thus, PALME appeared to be highly efficient for phospholipid removal. To further support this, qualitative (post-column infusion) and quantitative matrix effects were investigated with fluoxetine, fluvoxamine, and quetiapine as model analytes. No signs of matrix effects were observed. Finally, PALME was evaluated for the aforementioned drug substances, and data were in accordance with European Medicines Agency (EMA) guidelines. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Strong Cosmic Censorship

    NASA Astrophysics Data System (ADS)

    Isenberg, James

    2017-01-01

    The Hawking-Penrose theorems tell us that solutions of Einstein's equations are generally singular, in the sense of the incompleteness of causal geodesics (the paths of physical observers). These singularities might be marked by the blowup of curvature and therefore crushing tidal forces, or by the breakdown of physical determinism. Penrose has conjectured (in his `Strong Cosmic Censorship Conjecture`) that it is generically unbounded curvature that causes singularities, rather than causal breakdown. The verification that ``AVTD behavior'' (marked by the domination of time derivatives over space derivatives) is generically present in a family of solutions has proven to be a useful tool for studying model versions of Strong Cosmic Censorship in that family. I discuss some of the history of Strong Cosmic Censorship, and then discuss what is known about AVTD behavior and Strong Cosmic Censorship in families of solutions defined by varying degrees of isometry, and discuss recent results which we believe will extend this knowledge and provide new support for Strong Cosmic Censorship. I also comment on some of the recent work on ``Weak Null Singularities'', and how this relates to Strong Cosmic Censorship.

  16. 21 CFR 314.440 - Addresses for applications and abbreviated applications.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... mail code for the Office of Generic Drugs is HFD-600, the mail codes for the Divisions of Chemistry I... leukapheresis; (3) Blood component processing solutions and shelf life extenders; and (4) Oxygen carriers. [50...

  17. 21 CFR 314.440 - Addresses for applications and abbreviated applications.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... mail code for the Office of Generic Drugs is HFD-600, the mail codes for the Divisions of Chemistry I... leukapheresis; (3) Blood component processing solutions and shelf life extenders; and (4) Oxygen carriers. [50...

  18. 21 CFR 314.440 - Addresses for applications and abbreviated applications.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... mail code for the Office of Generic Drugs is HFD-600, the mail codes for the Divisions of Chemistry I... leukapheresis; (3) Blood component processing solutions and shelf life extenders; and (4) Oxygen carriers. [50...

  19. 21 CFR 314.440 - Addresses for applications and abbreviated applications.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... mail code for the Office of Generic Drugs is HFD-600, the mail codes for the Divisions of Chemistry I... leukapheresis; (3) Blood component processing solutions and shelf life extenders; and (4) Oxygen carriers. [50...

  20. A new class of asymptotically non-chaotic vacuum singularities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klinger, Paul, E-mail: paul.klinger@univie.ac.at

    2015-12-15

    The BKL conjecture, stated in the 1960s and early 1970s by Belinski, Khalatnikov and Lifschitz, proposes a detailed description of the generic asymptotic dynamics of spacetimes as they approach a spacelike singularity. It predicts complicated chaotic behaviour in the generic case, but simpler non-chaotic one in cases with symmetry assumptions or certain kinds of matter fields. Here we construct a new class of four-dimensional vacuum spacetimes containing spacelike singularities which show non-chaotic behaviour. In contrast with previous constructions, no symmetry assumptions are made. Rather, the metric is decomposed in Iwasawa variables and conditions on the asymptotic evolution of some ofmore » them are imposed. The constructed solutions contain five free functions of all space coordinates, two of which are constrained by inequalities. We investigate continuous and discrete isometries and compare the solutions to previous constructions. Finally, we give the asymptotic behaviour of the metric components and curvature.« less

  1. Load-Flow in Multiphase Distribution Networks: Existence, Uniqueness, Non-Singularity, and Linear Models

    DOE PAGES

    Bernstein, Andrey; Wang, Cong; Dall'Anese, Emiliano; ...

    2018-01-01

    This paper considers unbalanced multiphase distribution systems with generic topology and different load models, and extends the Z-bus iterative load-flow algorithm based on a fixed-point interpretation of the AC load-flow equations. Explicit conditions for existence and uniqueness of load-flow solutions are presented. These conditions also guarantee convergence of the load-flow algorithm to the unique solution. The proposed methodology is applicable to generic systems featuring (i) wye connections; (ii) ungrounded delta connections; (iii) a combination of wye-connected and delta-connected sources/loads; and, (iv) a combination of line-to-line and line-to-grounded-neutral devices at the secondary of distribution transformers. Further, a sufficient condition for themore » non-singularity of the load-flow Jacobian is proposed. Finally, linear load-flow models are derived, and their approximation accuracy is analyzed. Theoretical results are corroborated through experiments on IEEE test feeders.« less

  2. Load-Flow in Multiphase Distribution Networks: Existence, Uniqueness, Non-Singularity, and Linear Models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bernstein, Andrey; Wang, Cong; Dall'Anese, Emiliano

    This paper considers unbalanced multiphase distribution systems with generic topology and different load models, and extends the Z-bus iterative load-flow algorithm based on a fixed-point interpretation of the AC load-flow equations. Explicit conditions for existence and uniqueness of load-flow solutions are presented. These conditions also guarantee convergence of the load-flow algorithm to the unique solution. The proposed methodology is applicable to generic systems featuring (i) wye connections; (ii) ungrounded delta connections; (iii) a combination of wye-connected and delta-connected sources/loads; and, (iv) a combination of line-to-line and line-to-grounded-neutral devices at the secondary of distribution transformers. Further, a sufficient condition for themore » non-singularity of the load-flow Jacobian is proposed. Finally, linear load-flow models are derived, and their approximation accuracy is analyzed. Theoretical results are corroborated through experiments on IEEE test feeders.« less

  3. Solar system constraints on disformal gravity theories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ip, Hiu Yan; Schmidt, Fabian; Sakstein, Jeremy, E-mail: iphys@mpa-garching.mpg.de, E-mail: jeremy.sakstein@port.ac.uk, E-mail: fabians@mpa-garching.mpg.de

    Disformal theories of gravity are scalar-tensor theories where the scalar couples derivatively to matter via the Jordan frame metric. These models have recently attracted interest in the cosmological context since they admit accelerating solutions. We derive the solution for a static isolated mass in generic disformal gravity theories and transform it into the parameterised post-Newtonian form. This allows us to investigate constraints placed on such theories by local tests of gravity. The tightest constraints come from preferred-frame effects due to the motion of the Solar System with respect to the evolving cosmological background field. The constraints we obtain improve uponmore » the previous solar system constraints by two orders of magnitude, and constrain the scale of the disformal coupling for generic models to ℳ ∼> 100 eV. These constraints render all disformal effects irrelevant for cosmology.« less

  4. Generic mission planning concepts for space astronomy missions

    NASA Technical Reports Server (NTRS)

    Guffin, O. T.; Onken, J. F.

    1993-01-01

    The past two decades have seen the rapid development of space astronomy, both manned and unmanned, and the concurrent proliferation of the operational concepts and software that have been produced to support each individual project. Having been involved in four of these missions since the '70's and three yet to fly in the present decade, the authors believe it is time to step back and evaluate this body of experience from a macro-systems point of view to determine the potential for generic mission planning concepts that could be applied to future missions. This paper presents an organized evaluation of astronomy mission planning functions, functional flows, iteration cycles, replanning activities, and the requirements that drive individual concepts to specific solutions. The conclusions drawn from this exercise are then used to propose a generic concept that could support multiple missions.

  5. Continuations of the nonlinear Schrödinger equation beyond the singularity

    NASA Astrophysics Data System (ADS)

    Fibich, G.; Klein, M.

    2011-07-01

    We present four continuations of the critical nonlinear Schrödinger equation (NLS) beyond the singularity: (1) a sub-threshold power continuation, (2) a shrinking-hole continuation for ring-type solutions, (3) a vanishing nonlinear-damping continuation and (4) a complex Ginzburg-Landau (CGL) continuation. Using asymptotic analysis, we explicitly calculate the limiting solutions beyond the singularity. These calculations show that for generic initial data that lead to a loglog collapse, the sub-threshold power limit is a Bourgain-Wang solution, both before and after the singularity, and the vanishing nonlinear-damping and CGL limits are a loglog solution before the singularity, and have an infinite-velocity expanding core after the singularity. Our results suggest that all NLS continuations share the universal feature that after the singularity time Tc, the phase of the singular core is only determined up to multiplication by eiθ. As a result, interactions between post-collapse beams (filaments) become chaotic. We also show that when the continuation model leads to a point singularity and preserves the NLS invariance under the transformation t → -t and ψ → ψ*, the singular core of the weak solution is symmetric with respect to Tc. Therefore, the sub-threshold power and the shrinking-hole continuations are symmetric with respect to Tc, but continuations which are based on perturbations of the NLS equation are generically asymmetric.

  6. A black hole with torsion in 5D Lovelock gravity

    NASA Astrophysics Data System (ADS)

    Cvetković, B.; Simić, D.

    2018-03-01

    We analyze static spherically symmetric solutions of five dimensional (5D) Lovelock gravity in the first order formulation. In the Riemannian sector, when torsion vanishes, the Boulware–Deser black hole represents a unique static spherically symmetric black hole solution for the generic choice of the Lagrangian parameters. We show that a special choice of the Lagrangian parameters, different from the Lovelock Chern–Simons gravity, leads to the existence of a static black hole solution with torsion, the metric of which is asymptotically anti-de Sitter (AdS). We calculate the conserved charges and thermodynamical quantities of this black hole solution.

  7. Oscillating and static universes from a single barotropic fluid

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kehayias, John; Scherrer, Robert J.

    We consider cosmological solutions to general relativity with a single barotropic fluid, where the pressure is a general function of the density, p=f(ρ). We derive conditions for static and oscillating solutions and provide examples, extending earlier work to these simpler and more general single-fluid cosmologies. Generically we expect such solutions to suffer from instabilities, through effects such as quantum fluctuations or tunneling to zero size. We also find a classical instability (“no-go” theorem) for oscillating solutions of a single barotropic perfect fluid due to a necessarily negative squared sound speed.

  8. Oscillating and static universes from a single barotropic fluid

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kehayias, John; Scherrer, Robert J., E-mail: john.kehayias@vanderbilt.edu, E-mail: robert.scherrer@vanderbilt.edu

    We consider cosmological solutions to general relativity with a single barotropic fluid, where the pressure is a general function of the density, p = f(ρ). We derive conditions for static and oscillating solutions and provide examples, extending earlier work to these simpler and more general single-fluid cosmologies. Generically we expect such solutions to suffer from instabilities, through effects such as quantum fluctuations or tunneling to zero size. We also find a classical instability (''no-go'' theorem) for oscillating solutions of a single barotropic perfect fluid due to a necessarily negative squared sound speed.

  9. 78 FR 50447 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Cleanup...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ... for OMB Review; Comment Request; Cleanup Program for Accumulations of Coal and Float Coal Dusts, Loose Coal, and Other Combustibles ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the... (ICR) proposal; titled, ``Cleanup Program for Accumulations of Coal and Float Coal Dusts, Loose Coal...

  10. Grants to Faith-Based Organizations, Fiscal Year 2004

    ERIC Educational Resources Information Center

    The White House, 2005

    2005-01-01

    The data included in this report reflects a review of 151 Federally administered programs at six Federal agencies (HHS, HUD, ED, DOL, DOJ, and USDA), and 17 program areas at USAID. It includes only those programs that utilize competitively awarded grants for which faith-based and community organizations (FBCOs) were eligible to apply and…

  11. 75 FR 71513 - Senior Community Service Employment Program; Notice of Proposed Rulemaking, Additional Indicator...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ... to the current measures of employment retention and customer satisfaction. DOL intends for the new...) Retention in unsubsidized employment for 1 year; (2) satisfaction of the participants, employers, and their... unsubsidized employment for 1 year; and (2) the satisfaction of participants, employers and their host agencies...

  12. 77 FR 57156 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Safety...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ... used to prevent the fall of roof, face, and rib. Advancements in technology of roof and rock bolts and... information technology, e.g., permitting electronic submission of responses. Agency: DOL-MSHA. Title of... Control Number: 1219-0121. Affected Public: Private Sector--businesses or other for profits. Total...

  13. 42 CFR 82.27 - How can claimants obtain reviews of their NIOSH dose reconstruction results by NIOSH?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... METHODS FOR CONDUCTING DOSE RECONSTRUCTION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION... estimated in the completed dose reconstructions; or (2) NIOSH changes a scientific element underlying dose..., the methods employed in the review, and the review findings to the claimant, DOL, and DOE. ...

  14. 42 CFR 82.27 - How can claimants obtain reviews of their NIOSH dose reconstruction results by NIOSH?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... METHODS FOR CONDUCTING DOSE RECONSTRUCTION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION... estimated in the completed dose reconstructions; or (2) NIOSH changes a scientific element underlying dose..., the methods employed in the review, and the review findings to the claimant, DOL, and DOE. ...

  15. 42 CFR 82.27 - How can claimants obtain reviews of their NIOSH dose reconstruction results by NIOSH?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... METHODS FOR CONDUCTING DOSE RECONSTRUCTION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION... estimated in the completed dose reconstructions; or (2) NIOSH changes a scientific element underlying dose..., the methods employed in the review, and the review findings to the claimant, DOL, and DOE. ...

  16. 42 CFR 82.27 - How can claimants obtain reviews of their NIOSH dose reconstruction results by NIOSH?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... METHODS FOR CONDUCTING DOSE RECONSTRUCTION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION... estimated in the completed dose reconstructions; or (2) NIOSH changes a scientific element underlying dose..., the methods employed in the review, and the review findings to the claimant, DOL, and DOE. ...

  17. 20 CFR 655.1292 - Authority of ETA-OFLC.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Authority of ETA-OFLC. 655.1292 Section 655... Employment in the United States (H-2A Workers) § 655.1292 Authority of ETA-OFLC. Temporary agricultural labor... Department of Labor's (the Department or DOL) Employment & Training Administration (ETA), who, in turn, may...

  18. 77 FR 71634 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Employment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ... Training Administration (ETA) sponsored information collection request (ICR) titled, ``Employment and Training Administration Financial Report,'' (Forms ETA-9130, ETA-9130-A, and ETA-9130-B) to the Office of... Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room 10235, 725 17th...

  19. The Quantum Opportunity Program Demonstration: Final Impacts

    ERIC Educational Resources Information Center

    Schirm, Allen; Stuart, Elizabeth; McKie, Allison

    2006-01-01

    From July 1995 through September 2001, the U.S. Department of Labor (DOL) and the Ford Foundation (Ford) operated a demonstration of the Quantum Opportunity Program (QOP). QOP offered intensive and comprehensive services to help at-risk youth graduate from high school and enroll in postsecondary education or training. QOP was mainly an…

  20. 77 FR 71635 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ... of Applications and Grants for Self Employment Assistance Program,'' to the Office of Management and... for OMB Review; Comment Request; State Administration of Applications and Grants for Self Employment... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room...

  1. 77 FR 38657 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Hazardous...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    .... SUMMARY: On June 30, 2012, the Department of Labor (DOL) will submit the Occupational Safety and Health... the safety and health hazards associated with hazardous waste operations and emergency response to... adequate compliance with the Standard's safety and health provisions. An employer's failure to collect and...

  2. 78 FR 52803 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Additional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-26

    ... Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled... Paperwork Reduction Act (PRA) of 1995 (44 U.S.C. 3501 et seq.). DATES: Submit comments on or before... Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-OSHA, Office of Management and Budget, Room...

  3. 42 CFR 81.24 - Guidelines for leukemia.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Guidelines for leukemia. 81.24 Section 81.24 Public... Causation § 81.24 Guidelines for leukemia. (a) For claims involving leukemia, DOL will calculate one or more probability of causation estimates from up to three of the four alternate leukemia risk models included in...

  4. 42 CFR 81.25 - Guidelines for claims including two or more primary cancers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... cancers. 81.25 Section 81.25 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Estimate Probability of Causation § 81.25 Guidelines for claims including two or more primary cancers. For claims including two or more primary cancers, DOL will use NIOSH-IREP to calculate the estimated...

  5. 78 FR 36596 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Death Gratuity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... for OMB Review; Comment Request; Death Gratuity ACTION: Notice. SUMMARY: The Department of Labor (DOL... request (ICR) revision titled, ``Death Gratuity,'' to the Office of Management and Budget (OMB) for review... (FECA) by establishing a FECA death gratuity benefit of up to $100,000 for eligible beneficiaries of...

  6. 78 FR 64979 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... and Notice of Law Enforcement Officer's Death ACTION: Notice. SUMMARY: The Department of Labor (DOL... Notice of Law Enforcement Officer's Death,'' to the Office of Management and Budget (OMB) for review and... Law Enforcement Officer's Death, Form (CA-722), when seeking Federal Employees' Compensation Act (5 U...

  7. 20 CFR 655.185 - Job service complaint system; enforcement of work contracts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Job service complaint system; enforcement of... Job service complaint system; enforcement of work contracts. (a) Filing with DOL. Complaints arising under this subpart must be filed through the Job Service Complaint System, as described in 20 CFR part...

  8. 77 FR 46523 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Prohibited...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ... by Index and Model-Driven Funds ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting...) titled, ``Prohibited Transaction Class Exemption for Cross-Trades of Securities by Index and Model-Driven... and Model-Driven Funds permits cross-trades of securities between index and model-driven funds managed...

  9. 42 CFR 81.24 - Guidelines for leukemia.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Guidelines for leukemia. 81.24 Section 81.24 Public... Causation § 81.24 Guidelines for leukemia. (a) For claims involving leukemia, DOL will calculate one or more probability of causation estimates from up to three of the four alternate leukemia risk models included in...

  10. 78 FR 45972 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; High...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... Coal Mines ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Mine Safety and... Continuous Mining Machines Standards for Underground Coal Mines,'' to the Office of Management and Budget... continuous mining machines (HVCMM) in underground coal mines by requiring records of testing, examination and...

  11. 20 CFR 655.141 - Notice of deficiency.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... day delivery a written request to the Chief ALJ of DOL and simultaneously serve a copy on the CO. The... § 655.141 Notice of deficiency. (a) Notification timeline. If the CO determines the Application for... meet the requirements set forth in this subpart, the CO will notify the employer within 7 calendar days...

  12. 20 CFR 655.141 - Notice of deficiency.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... day delivery a written request to the Chief ALJ of DOL and simultaneously serve a copy on the CO. The... § 655.141 Notice of deficiency. (a) Notification timeline. If the CO determines the Application for... meet the requirements set forth in this subpart, the CO will notify the employer within 7 calendar days...

  13. 20 CFR 655.165 - Partial certification.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... certification. The CO may issue a partial certification, reducing either the period of need or the number of H-2A workers being requested or both for certification, based upon information the CO receives during... delivery a written request to the Chief ALJ of DOL (giving the address) and simultaneously serve a copy on...

  14. 20 CFR 655.165 - Partial certification.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... certification. The CO may issue a partial certification, reducing either the period of need or the number of H-2A workers being requested or both for certification, based upon information the CO receives during... delivery a written request to the Chief ALJ of DOL (giving the address) and simultaneously serve a copy on...

  15. Upskilling the Aerospace Workforce in Washington. Scaling Change: Air Washington Consortium

    ERIC Educational Resources Information Center

    Bragg, D. D.

    2016-01-01

    Several federal grants prioritized the role of community colleges in education and training in recent years, and one of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (DOL). Beginning October 2011, these $2 billion capacity-building…

  16. 42 CFR 81.25 - Guidelines for claims including two or more primary cancers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... cancers. 81.25 Section 81.25 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Estimate Probability of Causation § 81.25 Guidelines for claims including two or more primary cancers. For claims including two or more primary cancers, DOL will use NIOSH-IREP to calculate the estimated...

  17. Expanding Student Support Services. Scaling Change: MoHealthWINs Consortium

    ERIC Educational Resources Information Center

    Kirby, C. L.

    2016-01-01

    Several federal grants prioritized the role of community colleges in education and training in recent years, and one of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (DOL). Beginning October 2011, these $2 billion capacity-building…

  18. 76 FR 31364 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Fire Brigades

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... for OMB Review; Comment Request; Fire Brigades ACTION: Notice. SUMMARY: The Department of Labor (DOL... collection request (ICR) titled, ``Fire Brigades,'' to the Office of Management and Budget (OMB) for review... by e-mail at [email protected] . SUPPLEMENTARY INFORMATION: The Fire Brigade Standard codified...

  19. 76 FR 68219 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... for OMB Review; Comment Request; Impact Evaluation of the YouthBuild Program ACTION: Notice. SUMMARY... proposal for a new information collection titled, ``Impact Evaluation of the YouthBuild Program,'' to the... support of an impact evaluation of the YouthBuild Program. Specifically, the DOL seeks to conduct a census...

  20. 42 CFR 81.24 - Guidelines for leukemia.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Guidelines for leukemia. 81.24 Section 81.24 Public... Causation § 81.24 Guidelines for leukemia. (a) For claims involving leukemia, DOL will calculate one or more probability of causation estimates from up to three of the four alternate leukemia risk models included in...

  1. 42 CFR 81.24 - Guidelines for leukemia.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Guidelines for leukemia. 81.24 Section 81.24 Public... Causation § 81.24 Guidelines for leukemia. (a) For claims involving leukemia, DOL will calculate one or more probability of causation estimates from up to three of the four alternate leukemia risk models included in...

  2. 42 CFR 81.24 - Guidelines for leukemia.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Guidelines for leukemia. 81.24 Section 81.24 Public... Causation § 81.24 Guidelines for leukemia. (a) For claims involving leukemia, DOL will calculate one or more probability of causation estimates from up to three of the four alternate leukemia risk models included in...

  3. 78 FR 69448 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Crawler...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    .... SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled, ``Crawler, Locomotive, and Truck Cranes... must be generated. Occupational Safety and Health Act sections 6(b)(7), 29 U.S.C. 655(b)(7), and 8(c...

  4. 77 FR 16265 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Permit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ... Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored... . SUPPLEMENTARY INFORMATION: Under the authority granted by the Occupational Safety and Health Act, 29 U.S.C. 651 et seq., the OSHA published at 29 CFR 1910.146 a safety standard for general industry regulating...

  5. 78 FR 77715 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Access to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    .... SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled, ``Access to Employee Exposure and Medical... Occupational Safety and Health Act authorizes this information collection. See 29 U.S.C. 651, 655, and 657...

  6. 76 FR 30973 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... Fitness ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Mine Safety and Health... Program and Man Hoist Operators Physical Fitness,'' to the Office of Management and Budget (OMB) for... Fitness. OMB Control Number: 1219-0127. Affected Public: Private Sector--Businesses or other for-profits...

  7. 29 CFR 35.24 - Designation of responsible employee.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Designation of responsible employee. 35.24 Section 35.24 Labor Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF LABOR Duties of DOL Recipients § 35.24...

  8. 42 CFR 81.6 - Use of radiation dose information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Use of radiation dose information. 81.6 Section 81... Probability of Causation § 81.6 Use of radiation dose information. Determining probability of causation will require the use of radiation dose information provided to DOL by the National Institute for Occupational...

  9. 42 CFR 81.6 - Use of radiation dose information.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Use of radiation dose information. 81.6 Section 81... Probability of Causation § 81.6 Use of radiation dose information. Determining probability of causation will require the use of radiation dose information provided to DOL by the National Institute for Occupational...

  10. 42 CFR 81.6 - Use of radiation dose information.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Use of radiation dose information. 81.6 Section 81... Probability of Causation § 81.6 Use of radiation dose information. Determining probability of causation will require the use of radiation dose information provided to DOL by the National Institute for Occupational...

  11. 42 CFR 81.6 - Use of radiation dose information.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Use of radiation dose information. 81.6 Section 81... Probability of Causation § 81.6 Use of radiation dose information. Determining probability of causation will require the use of radiation dose information provided to DOL by the National Institute for Occupational...

  12. 75 FR 3911 - Advisory Board on Radiation and Worker Health (ABRWH or Advisory Board), National Institute for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-25

    ...: The Advisory Board was established under the Energy Employees Occupational Illness Compensation... employees at any Department of Energy facility who were exposed to radiation but for whom it is not feasible... Labor (DOL) Program Update; Department of Energy (DOE) Program Update; OCAS Science Update; Special...

  13. 78 FR 29778 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... for OMB Review; Comment Request; Notification of Employee Rights Under Federal Labor Laws ACTION... their rights as employees under Federal labor laws. Regulations 29 CFR 471.11 provides for DOL to accept... Federal Labor Laws,'' to the Office of Management and Budget (OMB) for review and approval for continued...

  14. 75 FR 67120 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Senior...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-01

    ... DEPARTMENT OF LABOR Office of the Secretary Agency Information Collection Activities; Submission... System ACTION: Notice. SUMMARY: The Department of Labor (DOL) hereby announces submission of the... Act of 1995 (PRA), Public Law 104-13, 44 U.S.C. chapter 35. DATES: Submit comments on or before...

  15. Comments on: "Perinatal toxicity of cyfluthrin in Mice: developmental and behavioral effects" by Soni et al, which is accepted in Human & Experimental Toxicology (DOl: 10.1177/0960327110391386)

    EPA Science Inventory

    Soni and colleagues recently reported that perinatal maternal exposure to cyfluthrin, a pyrethroid insecticide, caused fetal malformations and behavioral changes in offspring, including skeletal malformations and alterations in righting reflexes and locomotion (Soni et al., 2011)...

  16. The Sky's the Limit: Integrating Geospatial Tools with Pre-College Youth Education

    ERIC Educational Resources Information Center

    McGee, John; Kirwan, Jeff

    2010-01-01

    Geospatial tools, which include global positioning systems (GPS), geographic information systems (GIS), and remote sensing, are increasingly driving a variety of applications. Local governments and private industry are embracing these tools, and the public is beginning to demand geospatial services. The U.S. Department of Labor (DOL) reported that…

  17. 20 CFR 667.500 - What procedures apply to the resolution of findings arising from audits, investigations...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., monitoring and oversight reviews? (a) Resolution of subrecipient-level findings. (1) The Governor is... recipient level OMB Circular A-133 audits. (2) The Secretary uses the DOL audit resolution process... (including OMB Circular A-133 audits) of subrecipients. (2) A State must utilize the audit resolution, debt...

  18. 76 FR 33786 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Steel Erection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... hazards and that they are notified that building materials, components, steel structures, and fall... for OMB Review; Comment Request; Steel Erection ACTION: Notice. SUMMARY: The Department of Labor (DOL... collection request (ICR) titled, ``Steel Erection (29 CFR part 1926, subpart R),'' to the Office of...

  19. 77 FR 2760 - Proposed Information Collection Request (ICR) for the Mining Voice in the Workplace Survey...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... DEPARTMENT OF LABOR Proposed Information Collection Request (ICR) for the Mining Voice in the...)(A)]. This program helps to ensure that required data can be provided in the desired format...' voice in mining workplaces under the jurisdiction of DOL's Mine Safety and Health Administration (MSHA...

  20. 76 FR 59165 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Attestation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... at Locations in the State of Alaska ACTION: Notice. SUMMARY: The Department of Labor (DOL) is...) titled, ``Attestation by Employers Using Crewmembers for Longshore Activities at Locations in the State... Crewmembers for Longshore Activities at Locations in the State of Alaska. OMB Control Number: 1205-0352...

  1. 77 FR 23281 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; O*Net Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... design, human resources functions and workforce investment efforts. The data collection methodology... collection request (ICR) titled, ``O*Net Data Collection Program,'' to the Office of Management and Budget... Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA, Office of Management and Budget, Room 10235...

  2. 77 FR 44675 - Agency Information Collection Activities; Submission for OMB Review; Comment Request: Site Visit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ... Reinvestment Act Funded Grants; Job Training Evaluations ACTION: Notice. SUMMARY: The Department of Labor (DOL... Act funded Grants; Job Training Evaluations,'' to the Office of Management and Budget (OMB) for review... Green Jobs training programs. The overall aim of these evaluations is to determine the extent to which...

  3. 76 FR 4377 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Affordable...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ... Extension of Dependent Coverage ACTION: Notice. SUMMARY: The Department of Labor (DOL) hereby announces the... Coverage,'' to the Office of Management and Budget (OMB) for review and approval for continued use in... an enrollment opportunity to individuals whose coverage ended, or who were denied coverage (or were...

  4. 75 FR 1087 - Submission for OMB Review: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-08

    ... DEPARTMENT OF LABOR Office of the Secretary Submission for OMB Review: Comment Request January 4, 2010. The Department of Labor (DOL) hereby announces the submission of the following public information collection request (ICR) to the Office of Management and Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act of...

  5. 42 CFR 81.25 - Guidelines for claims including two or more primary cancers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... cancers. 81.25 Section 81.25 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Estimate Probability of Causation § 81.25 Guidelines for claims including two or more primary cancers. For claims including two or more primary cancers, DOL will use NIOSH-IREP to calculate the estimated...

  6. 42 CFR 81.25 - Guidelines for claims including two or more primary cancers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... cancers. 81.25 Section 81.25 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Estimate Probability of Causation § 81.25 Guidelines for claims including two or more primary cancers. For claims including two or more primary cancers, DOL will use NIOSH-IREP to calculate the estimated...

  7. 42 CFR 81.25 - Guidelines for claims including two or more primary cancers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... cancers. 81.25 Section 81.25 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Estimate Probability of Causation § 81.25 Guidelines for claims including two or more primary cancers. For claims including two or more primary cancers, DOL will use NIOSH-IREP to calculate the estimated...

  8. 29 CFR 14.20 - Dissemination to individuals and firms outside the executive branch.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... individual basis. (b) Secret and Confidential information. Subject to the restrictions below, Secret or Confidential information may be furnished to an individual or firm outside the executive branch if the action... the appropriate DOL clearance, or at least clearance for the same or higher classification for another...

  9. Generic legislation of new psychoactive drugs.

    PubMed

    van Amsterdam, Jan; Nutt, David; van den Brink, Wim

    2013-03-01

    New psychoactive drugs (NPDs, new psychoactive substances) enter the market all the time. However, it takes several months to ban these NPDs and immediate action is generally not possible. Several European countries and drug enforcement officers insist on a faster procedure to ban NPDs. Introduction of generic legislation, in which clusters of psychotropic drugs are banned in advance, has been mentioned as a possible solution. Here we discuss the pros and cons of such an approach. First, generic legislation could unintentionally increase the expenditures of enforcement, black market practices, administrative burden and health risks for users. Second, it may have a negative impact on research and the development of new treatments. Third, due to the complexity of generic legislation, problems in the enforcement are anticipated due to lack of knowledge about the chemical nomenclature. Finally, various legal options are already available to ban the use, sale and trade of NPDs. We therefore conclude that the currently used scientific benefit-risk evaluation should be continued to limit the adverse health effects of NPDs. Only in emergency cases, where fatal incidents (may) occur, should this approach be overruled.

  10. Mathematical Analysis of a Coarsening Model with Local Interactions

    NASA Astrophysics Data System (ADS)

    Helmers, Michael; Niethammer, Barbara; Velázquez, Juan J. L.

    2016-10-01

    We consider particles on a one-dimensional lattice whose evolution is governed by nearest-neighbor interactions where particles that have reached size zero are removed from the system. Concentrating on configurations with infinitely many particles, we prove existence of solutions under a reasonable density assumption on the initial data and show that the vanishing of particles and the localized interactions can lead to non-uniqueness. Moreover, we provide a rigorous upper coarsening estimate and discuss generic statistical properties as well as some non-generic behavior of the evolution by means of heuristic arguments and numerical observations.

  11. Vacuum solutions admitting a geodesic null congruence with shear proportional to expansion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kupeli, A.H.

    Algebraically general, nontwisting solutions for the vacuum to vacuum generalized Kerr--Schild (GKS) transformation are obtained. These solutions admit a geodesic null congruence with shear proportional to expansion. In the Newman--Penrose formalism, if l/sup ..mu../ is chosen to be the null vector of the GKS transformation, this property is stated as sigma = arho and Da = 0. It is assumed that a is a constant, and the background is chosen as a pp-wave solution. For generic values of a, the GKS metrics consist of the Kasner solutions. For a = +- (1 +- (2)/sup 1/2/), there are solutions with lessmore » symmetries including special cases of the Kota--Perjes and Lukacs solutions.« less

  12. Analysis of Near Simultaneous Jimsphere and AMPS High Resolution Wind Profiles

    NASA Technical Reports Server (NTRS)

    Adelfang, S. I.

    2003-01-01

    The high-resolution wind profile of the Automated Meteorological Profiling System (HRAMPS) is the proposed replacement for the Jimsphere measurement system used to support NASA Shuttle launches from the Eastern Test Range (ETR). Samples of twenty-six ETR near simultaneous Jimsphere and HRAMPS wind profiles were obtained for Shuttle program HRAMPS certification studies. Shuttle systems engineering certification is to ensure that spacecraft and launch vehicle systems performance and safety evaluations for each launch (derived from flight simulations with Jimsphere wind profile data bases) retain their validity when HRAMPS profiles are used on day-of-launch (DOL) in trajectory and loads simulations to support the commit-to-launch decision. This paper describes a statistical analysis of the near simultaneous profiles. In principle the differences between a Jimsphere profile and an HRAMPS profile should be attributed to tracking technology (radar versus GPS tracking of a Jimsphere flight element) and the method for derivation of wind vectors from the raw tracking data. In reality, it is not technically feasible to track the same Jimsphere balloon with the two systems. The aluminized Mylar surface of the standard Jimsphere flight element facilitates radar tracking, but it interferes with HRAMPS during simultaneous tracking. Suspending a radar reflector from an HRAMPS flight element (Jimsphere without aluminized coating) does not produce satisfactory Jimsphere profiles because of intermittent radar returns. Thus, differences between the Jimsphere and HRAMPS profiles are also attributed to differences in the trajectories of separate flight elements. Because of small sample size and a test period limited to one winter season, test measurements during extreme high winds aloft could not have been expected and did not occur. It is during the highest winds that the largest differences between Jimsphere and HRAMPS would occur because the distance between flight elements would be larger. Jimsphere radar tracking noise increases as a function of balloon displacement downrange. The Jimsphere data processing compensates for tracking signal/noise degradation by increasing the smoothing interval. The Jimsphere wind profile effective resolution is a function of downrange distance and altitude, whereas the effective resolution of the HRAMPS should be independent of those variables. The procedure used for editing Jimsphere spikes in Shuttle DOL profiles was not implemented for the Jimsphere profile measurements during the AMPS field tests. For this analysis a code was developed that essentially mimics DOL Jimsphere spike editing. Jimsphere profiles have somewhat more noise in the wavelength range less than 200m defined as the noise floor. No differences between Jimsphere and HRAMPS wind profile pairs have been found that would support denial of HRAMPS certification for application in Shuttle DOL applications. The reliability of the HRAMPS system, which is an important certification issue, is not addressed in this study.

  13. A multilayered water column in the Ediacaran Yangtze platform? Insights from carbonate and organic matter paired δ13C

    NASA Astrophysics Data System (ADS)

    Ader, M.; Macouin, M.; Trindade, R. I. F.; Hadrien, M.-H.; Yang, Z.; Sun, Z.; Besse, J.

    2009-10-01

    Large carbon isotope fluctuations have been systematically reported for Ediacaran carbonate rocks, the meaning of which remains controversial. In order to better understand the mechanisms behind such variations, we present new paired δ13C data on carbonates ( δ13C carb) and their associated organic matter ( δ13C org) from a shelf-margin section (Yangjiaping) of the Doushantuo Formation. In this section, the Doushantuo Formation starts with cap dolostones presenting δ13C carb values around - 5‰ and δ13C org values between - 30.3 and - 27.6‰. Up-section, phased variations in δ13C carb and δ13C org describe positive and negative excursions, while their difference (Δ 13C dol-org = δ13C carb - δ13C org) remains around + 29.2‰. These new data allow the first reconstruction of lateral variations of δ13C carb, δ13C org and Δ 13C carb-org for a shelf-to-basin cross-section of the Yangtze platform (South China) after integration with results reported previously for two other sections. Across the Yangtze platform, the isotope signals reveal strong lateral heterogeneities, with complex variations of δ13C carb and Δ 13C dol-org in the inner-shelf section, phased variations in the shelf-margin section with positive δ13C carb and Δ 13C dol-org close to 29‰, and dominantly negative δ13C carb with δ13C org as low as - 35‰ in the basin. These variations are incompatible with the idea that the δ13C carb can systematically be used as a proxy of ocean surface waters. Assuming that δ13C carb are acquired in bottom waters and/or upper sediments, we show that the heterogeneous δ13C carb and Δ 13C dol-org are compatible with a stratified water column composed of up to three layers: (i) an oxic surface layer, where dissolved inorganic carbon (DIC) is probably in isotope equilibrium with the atmosphere; (ii) an intermediate euxinic layer with a lower δ13C DIC due to organic matter oxidation by ongoing sulphate reduction; (iii) a bottom euxinic layer that seems to be restricted to the inner-shelf lagoonal facies, lacking sulphate, containing methane and with a higher δ13C DIC due to DIC production by methanogenesis. If our model holds true, it suggests that not only negative but also positive Ediacaran carbon isotope excursions may reflect ocean stratification, the positive excursion possibly recording a sulphate-free methanogenic layer at the bottom of restricted basins.

  14. News on Seeking Gaia's Astrometric Core Solution with AGIS

    NASA Astrophysics Data System (ADS)

    Lammers, U.; Lindegren, L.

    We report on recent new developments around the Astrometric Global Iterative Solution system. This includes the availability of an efficient Conjugate Gradient solver and the Generic Astrometric Calibration scheme that had been proposed a while ago. The number of primary stars to be included in the core solution is now believed to be significantly higher than the 100 Million that served as baseline until now. Cloud computing services are being studied as a possible cost-effective alternative to running AGIS on dedicated computing hardware at ESAC during the operational phase.

  15. Explicit solutions for exit-only radioactive decay chains

    NASA Astrophysics Data System (ADS)

    Yuan, Ding; Kernan, Warnick

    2007-05-01

    In this study, we extended Bateman's [Proc. Cambridge Philos. Soc. 15, 423 (1910)] original work for solving radioactive decay chains and explicitly derived analytic solutions for generic exit-only radioactive decay problems under given initial conditions. Instead of using the conventional Laplace transform for solving Bateman's equations, we used a much simpler algebraic approach. Finally, we discuss methods of breaking down certain classes of large decay chains into collections of simpler chains for easy handling.

  16. Determination of Static and Dynamic Stability Derivatives Using Beggar

    DTIC Science & Technology

    2008-03-01

    applies a symmetric Gauss - Seidel method , which solves the generic equation [A]x = b for x by dividing [A] into [A] = ([D][L])[U ] (2.68) 37 where D is...oscillations. Convergence studies on each of these parameters were performed to ensure both convergence and solution independence. Roll stability derivatives...aerodynamic stability parame- ters made dynamic solutions more difficult to compute and less reliable, but modern methods and resources are making this process

  17. 78 FR 67196 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Worker...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... employees at least the Federal minimum wage for all hours worked and overtime premium pay of time and one-half the regular rate of pay for all hours worked over forty (40) in a workweek. However, the FLSA...: The Department of Labor (DOL) is submitting the Wage and Hour Division (WHD) sponsored information...

  18. 21st Century Accountability: Perkins III and WIA. Information Paper 1002.

    ERIC Educational Resources Information Center

    Stevens, David W.

    The passage of the Carl D. Perkins Vocational and Applied Technology Education Amendments of 1998 (Perkins III) and the Workforce Investment Act of 1998 (WIA) marked a new era in the performance accountability partnership among the states, the U.S. Department of Education, and the U.S. Department of Labor (DOL). Evaluation of vocational education…

  19. 20 CFR 655.501 - Overview of responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... attestation process. Within DOL, the Employment and Training Administration (ETA) shall have responsibility... other than in the State of Alaska shall, as the first step, submit an attestation on Form ETA 9033, as described in § 655.510 of this part, to ETA at the address set forth at § 655.510(b) of this part. If ETA...

  20. 20 CFR 1.6 - How were many of OWCP's current functions administered in the past?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., DEPARTMENT OF LABOR ORGANIZATION AND PROCEDURES PERFORMANCE OF FUNCTIONS § 1.6 How were many of OWCP's... shall deem appropriate, authorizing the performance of any of his functions by any other officer, agency, or employee of the DOL. (b) In 1972, two separate organizational units were established within the...

  1. 42 CFR 81.5 - Use of personal and medical information.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... claimants under DOL regulations 20 CFR part 30: (a) Year of birth (b) Cancer diagnosis (by ICD-9 code) for primary and secondary cancers (c) Date of cancer diagnosis (d) Gender (e) Race/ethnicity (if the claim is for skin cancer or a secondary cancer for which skin cancer is a likely primary cancer) (f) Smoking...

  2. 42 CFR 81.21 - Cancers requiring the use of NIOSH-IREP.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Cancers requiring the use of NIOSH-IREP. 81.21... Probability of Causation § 81.21 Cancers requiring the use of NIOSH-IREP. (a) DOL will calculate probability of causation for all cancers, except chronic lymphocytic leukemia as provided under § 81.30, using...

  3. 20 CFR 703.202 - Identification of significant gaps in State guaranty fund coverage for LHWCA obligations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... RELATED STATUTES INSURANCE REGULATIONS Insurance Carrier Security Deposit Requirements § 703.202... amount of a carrier's required security deposit, the Office will consider the extent to which a State... Internet at http://www.dol.gov/esa/owcp/dlhwc/lstable.htm. These findings will indicate the extent of any...

  4. 77 FR 74879 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Explosive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ... Underground Gassy Mines ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Mine Safety... Materials and Blasting Units in Metal and Nonmetal Underground Gassy Mines,'' to the Office of Management... blasting capacity for some metal and nonmetal gassy mines, 30 CFR 57.22606(a) outlines the procedures for a...

  5. 77 FR 51827 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Ground...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ... for OMB Review; Comment Request; Ground Control Plans for Surface Coal Mines and Surface Work Areas of Underground Coal Mines ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Mine Safety... Control Plans for Surface Coal Mines and Surface Work Areas of Underground Coal Mines,'' to the Office of...

  6. 42 CFR 81.5 - Use of personal and medical information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... claimants under DOL regulations 20 CFR part 30: (a) Year of birth (b) Cancer diagnosis (by ICD-9 code) for primary and secondary cancers (c) Date of cancer diagnosis (d) Gender (e) Race/ethnicity (if the claim is for skin cancer or a secondary cancer for which skin cancer is a likely primary cancer) (f) Smoking...

  7. 42 CFR 81.21 - Cancers requiring the use of NIOSH-IREP.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Cancers requiring the use of NIOSH-IREP. 81.21... Probability of Causation § 81.21 Cancers requiring the use of NIOSH-IREP. (a) DOL will calculate probability of causation for all cancers, except chronic lymphocytic leukemia as provided under § 81.30, using...

  8. 76 FR 18254 - Proposed Information Collection Request (ICR) for the Family Medical Leave Act (FMLA) Employee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... WHD to determine how those policies affect the work-life balance of workers and the productivity and work flow of employers. The study enables DOL to shape future regulatory options, craft interpretive... Family and Medical Leave. The final report on this survey, titled ``A Workable Balance: Report to...

  9. 76 FR 61115 - Notice of Publication of 2011 Update to The Department of Labor's List of Goods From Countries...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ... Trafficking Victims Protection Reauthorization Act (TVPRA) of 2005. FOR FURTHER INFORMATION CONTACT: Director, Office of Child Labor, Forced Labor, and Human Trafficking, Bureau of International Labor Affairs, U.S...: http://www.dol.gov/ilab/programs/ocft/tvpra.htm . ILAB's Office of Child Labor, Forced Labor, and Human...

  10. Transforming College Practices and Student Experiences to Advance STEM Education. Scaling Change: National STEM Consortium

    ERIC Educational Resources Information Center

    Richie, D.

    2016-01-01

    Several federal grants prioritized the role of community colleges in education and training in recent years, and one of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (DOL). Beginning October 2011, these $2 billion capacity-building…

  11. 45 CFR 147.140 - Preservation of right to maintain existing coverage.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... Subject to paragraphs (f) and (g)(2) of this section, if a group health plan (including a group health... to be a grandfathered health plan. (2) Disclosure of grandfather status—(i) To maintain status as a... Labor at 1-866-444-3272 or www.dol.gov/ebsa/healthreform. This Web site has a table summarizing which...

  12. Digital and Online Learning in Vocational Education and Training in Serbia: A Case Study

    ERIC Educational Resources Information Center

    Brolpito, Alessandro; Lightfoot, Michael; Radišic, Jelena; Šcepanovic, Danijela

    2016-01-01

    This case study aims to identify relevant policies and practices for digital and online learning (DOL) in vocational education and training (VET) in Serbia, with a focus on initial VET (IVET). The study was commissioned by the European Training Foundation (ETF) with the following specific objectives: (1) gather information and analyse DOL…

  13. 29 CFR Appendix A to Part 35 - Age Distinctions in Statutes Affecting Financial Assistance Administered by DOL

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... waived by the Secretary, * * * in the case of an individual with a disability.” 20 CFR 670.400. 3. Indian... for the purpose of developing and implementing techniques and approaches, and demonstrating the..., provides that notwithstanding other provisions pertaining to payments in the case of deceased persons, if...

  14. 29 CFR Appendix A to Part 35 - Age Distinctions in Statutes Affecting Financial Assistance Administered by DOL

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... waived by the Secretary, * * * in the case of an individual with a disability.” 20 CFR 670.400. 3. Indian... for the purpose of developing and implementing techniques and approaches, and demonstrating the..., provides that notwithstanding other provisions pertaining to payments in the case of deceased persons, if...

  15. 29 CFR Appendix A to Part 35 - Age Distinctions in Statutes Affecting Financial Assistance Administered by DOL

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... waived by the Secretary, * * * in the case of an individual with a disability.” 20 CFR 670.400. 3. Indian... for the purpose of developing and implementing techniques and approaches, and demonstrating the..., provides that notwithstanding other provisions pertaining to payments in the case of deceased persons, if...

  16. 29 CFR Appendix A to Part 35 - Age Distinctions in Statutes Affecting Financial Assistance Administered by DOL

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... waived by the Secretary, * * * in the case of an individual with a disability.” 20 CFR 670.400. 3. Indian... for the purpose of developing and implementing techniques and approaches, and demonstrating the..., provides that notwithstanding other provisions pertaining to payments in the case of deceased persons, if...

  17. 76 FR 60532 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Miner's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ... Employment History ACTION: Notice. SUMMARY: The Department of Labor (DOL) is submitting the Office of Workers... Benefits Under the Black Lung Benefits Act and Employment History,'' to the Office of Management and Budget..., complete the Employment History (Form CM-911a) to list the coal miner's work history. This information...

  18. 29 CFR 14.22 - Availability of classified information to persons not employed by the Department of Labor.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Officer. (b) Access to Top Secret material. Access to Top Secret Information within the primary organizational units of the DOL by employees of other Federal agencies must be approved in advance by the Top Secret Control Officer of the primary organizational unit. (c) Access to Secret and Confidential...

  19. Catalogue of Workforce Information Sources: Decision Making Assistance for Regional Economic Development. U.S. Department of Labor, Employment and Training Administration

    ERIC Educational Resources Information Center

    US Department of Labor, 2009

    2009-01-01

    In early 2006, The U.S. Department of Labor (DOL), Employment and Training Administration (ETA) began an initiative called Workforce Innovation in Regional Economic Development (WIRED) to help regions create competitive conditions, integrate economic and workforce development activities, and demonstrate that talent development can successfully…

  20. 78 FR 70070 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... DOL released EBSA Field Assistance Bulletin (FAB) 2013-01 concerning the new disclosure requirements mandated by MAP-21 provisions. The FAB addresses a need for interim guidance pending the adoption of regulations or other guidance under ERISA section 101(f), as amended by the MAP-21. The FAB sets forth...

  1. 78 FR 31596 - Workforce Investment Act of 1998 (WIA); Notice of Incentive Funding Availability Based on Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ...The Department of Labor (DOL), in collaboration with the Department of Education (ED), announces that 15 States are eligible to apply for Workforce Investment Act (WIA) (Pub. L. 105-220, 29 U.S.C. 2801 et seq.) incentive grant awards authorized by section 503 of the WIA.

  2. Population Structure of Island-Associated Dolphins: Evidence from Photo-Identification of Common Bottlenose Dolphins (Tursiops truncatus) in the Main Hawaiian Islands

    DTIC Science & Technology

    2009-04-01

    primarily deep-water species ap- pear to exhibit high levels of fidelity to the islands, including rough-toothed dol- phins ( Steno bredanensis), and...and association patterns in a deep-water dolphin: Rough- toothed dolphins ( Steno bredanensis) in the Hawaiian Archipelago. Marine Mammal Science 24:535

  3. 77 FR 35058 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Pilot...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... for OMB Review; Comment Request; Pilot Surveys of Employee Voice in the Coal Mining Industry ACTION... the Coal Mining Industry,'' to the Office of Management and Budget (OMB) for review and approval for...' voice in mining workplaces under the jurisdiction of the MSHA. The DOL working definition for voice in...

  4. 77 FR 14831 - Agency Information Collection Activities; Submission for OMB Emergency Review: Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... any Federal or State job training program within the previous 180 days; and, the application must be... not and is not enrolled in a Federal or state job training program within 180 days of the application.... SUMMARY: The Department of Labor (DOL) has submitted the Employment and Training Administration (ETA...

  5. 78 FR 72716 - Proposed Extension of the Information Collections Pertaining to Special Employment Under the Fair...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... operations. See 29 CFR 530.101. Consistent with FLSA sections 11(d) and 14(c), the DOL's Wage and Hour... on the form. Frequency: On occasion. Total Burden Cost (capital/startup): $0. Total Burden Cost (operation/maintenance): $1,554. Dated: November 26, 2013. Mary Ziegler, Director, Division of Regulations...

  6. 77 FR 27796 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Statement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-11

    ... of Labor (DOL) is submitting the Office of RUN FRFMWorkers' Compensation Programs (OWCP) sponsored... work-related injury. A Federal employee can sustain a work-related injury, for which he or she is... create a legal liability for some third party to pay damages for the same injury. When this occurs, the...

  7. 42 CFR 81.5 - Use of personal and medical information.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... claimants under DOL regulations 20 CFR part 30: (a) Year of birth (b) Cancer diagnosis (by ICD-9 code) for primary and secondary cancers (c) Date of cancer diagnosis (d) Gender (e) Race/ethnicity (if the claim is for skin cancer or a secondary cancer for which skin cancer is a likely primary cancer) (f) Smoking...

  8. 42 CFR 81.5 - Use of personal and medical information.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... claimants under DOL regulations 20 CFR part 30: (a) Year of birth (b) Cancer diagnosis (by ICD-9 code) for primary and secondary cancers (c) Date of cancer diagnosis (d) Gender (e) Race/ethnicity (if the claim is for skin cancer or a secondary cancer for which skin cancer is a likely primary cancer) (f) Smoking...

  9. 42 CFR 81.5 - Use of personal and medical information.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... claimants under DOL regulations 20 CFR part 30: (a) Year of birth (b) Cancer diagnosis (by ICD-9 code) for primary and secondary cancers (c) Date of cancer diagnosis (d) Gender (e) Race/ethnicity (if the claim is for skin cancer or a secondary cancer for which skin cancer is a likely primary cancer) (f) Smoking...

  10. 20 CFR 667.170 - What responsibility review does the Department conduct for awards made under WIA title I...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... effective cash management or cost controls resulting in excess cash on hand; (11) Failure to ensure that a... consider the organization's history with regard to the management of other grants, including DOL grants... management system as required by Federal regulations; (4) Willful obstruction of the audit process; (5...

  11. Hydrogen and advanced aerospace materials

    NASA Technical Reports Server (NTRS)

    Nelson, Howard G.

    1988-01-01

    The hydrogen embrittlement is briefly reviewed and discussed in terms of specific structural materials considered for use on a generic, hydrogen-fueled, hypersonic aerospace vehicle. A few unusual hydrogen-material incompatibility concerns are identified and some solution methodologies are discussed that could potentially lessen these concerns.

  12. The Full Kostant-Toda Hierarchy on the Positive Flag Variety

    NASA Astrophysics Data System (ADS)

    Kodama, Yuji; Williams, Lauren

    2015-04-01

    We study some geometric and combinatorial aspects of the solution to the full Kostant-Toda (f-KT) hierarchy, when the initial data is given by an arbitrary point on the totally non-negative (tnn) flag variety of . The f-KT flows on the tnn flag variety are complete, and we show that their asymptotics are completely determined by the cell decomposition of the tnn flag variety given by Rietsch (Total positivity and real flag varieties. Ph.D. Thesis, Massachusetts Institute of Technology, Cambridge, 1998). Our results represent the first results on the asymptotics of the f-KT hierarchy (and even the f-KT lattice); moreover, our results are not confined to the generic flow, but cover non-generic flows as well. We define the f-KT flow on the weight space via the moment map, and show that the closure of each f-KT flow forms an interesting convex polytope which we call a Bruhat interval polytope. In particular, the Bruhat interval polytope for the generic flow is the permutohedron of the symmetric group . We also prove analogous results for the full symmetric Toda hierarchy, by mapping our f-KT solutions to those of the full symmetric Toda hierarchy. In the appendix we show that Bruhat interval polytopes are generalized permutohedra, in the sense of Postnikov (Int. Math. Res. Not. IMRN (6):1026-1106, 2009).

  13. Relationships between healthcare and research records.

    PubMed

    Duwe, Helmut

    2004-01-01

    The ultimate end-point of healthcare and health-related life sciences, more or less as regulatory idea, is the prevention and cure of diseases, considering the fate of individual patients as well as the challenge of providing sufficient care for all. However, all undertakings stand under the "proviso of rightness of action". The movement of evidence-based medicine has triggered a renaissance of systematic self-assurance of best practise. The systematic utilization of healthcare records and research study recordings in an inter-linked manner provides a better enabling environment to improve evidence. Good e-health must contribute to accumulate inter-generation clinical experience. Qualified research should ensure methodological strictness via gold standards like controlled, randomised and masked trials. Building information systems for e-health as well as for e-science bears as a special focus the mutual cross-fertilization of these application domains. Analysing a variety of building blocks shows that both areas can benefit from generic solution pattern, keeping in mind that each domain has distinguished knowledge realms. Generic patterns as well as distinguished special features are illustrated by analysing state of the art solutions plus some experimental approaches, as there are: the generic part of the HL7 V3 RIM, the RCRIM work, laboratory information handling, vital sign standardization efforts, like ECG information models.Finally, the precision of the usage of the ubiquitous term "metadata" is taken as example of an open issue.

  14. A generic implementation of replica exchange with solute tempering (REST2) algorithm in NAMD for complex biophysical simulations

    NASA Astrophysics Data System (ADS)

    Jo, Sunhwan; Jiang, Wei

    2015-12-01

    Replica Exchange with Solute Tempering (REST2) is a powerful sampling enhancement algorithm of molecular dynamics (MD) in that it needs significantly smaller number of replicas but achieves higher sampling efficiency relative to standard temperature exchange algorithm. In this paper, we extend the applicability of REST2 for quantitative biophysical simulations through a robust and generic implementation in greatly scalable MD software NAMD. The rescaling procedure of force field parameters controlling REST2 "hot region" is implemented into NAMD at the source code level. A user can conveniently select hot region through VMD and write the selection information into a PDB file. The rescaling keyword/parameter is written in NAMD Tcl script interface that enables an on-the-fly simulation parameter change. Our implementation of REST2 is within communication-enabled Tcl script built on top of Charm++, thus communication overhead of an exchange attempt is vanishingly small. Such a generic implementation facilitates seamless cooperation between REST2 and other modules of NAMD to provide enhanced sampling for complex biomolecular simulations. Three challenging applications including native REST2 simulation for peptide folding-unfolding transition, free energy perturbation/REST2 for absolute binding affinity of protein-ligand complex and umbrella sampling/REST2 Hamiltonian exchange for free energy landscape calculation were carried out on IBM Blue Gene/Q supercomputer to demonstrate efficacy of REST2 based on the present implementation.

  15. An Aerodynamic Analysis of a Spinning Missile with Dithering Canards

    NASA Technical Reports Server (NTRS)

    Meakin, Robert L.; Nygaard, Tor A.

    2003-01-01

    A generic spinning missile with dithering canards is used to demonstrate the utility of an overset structured grid approach for simulating the aerodynamics of rolling airframe missile systems. The approach is used to generate a modest aerodynamic database for the generic missile. The database is populated with solutions to the Euler and Navier-Stokes equations. It is used to evaluate grid resolution requirements for accurate prediction of instantaneous missile loads and the relative aerodynamic significance of angle-of-attack, canard pitching sequence, viscous effects, and roll-rate effects. A novel analytical method for inter- and extrapolation of database results is also given.

  16. 0-6766 : a generic mode choice model applicable for small and medium-sized MPOs : [project summary].

    DOT National Transportation Integrated Search

    2013-12-01

    Due to the projected population growth increase : in Texas and the continued increase in total : motorized vehicle miles traveled in Texas, the : Texas Department of Transportation (TxDOT) is : interested in examining multimodal solutions to : aid in...

  17. A generic method for the determination of acrylamide in thermally processed foods.

    PubMed

    Gökmen, Vural; Senyuva, Hamide Z

    2006-07-07

    A generic sample preparation method for the determination of acrylamide in foods was developed. The method entails extraction with methanol, purification with Carrez I and II solutions, evaporation and solvent change to water, and cleanup with Oasis HLB solid-phase extraction (SPE) cartridge. The final extract was analyzed by liquid chromatography-mass spectrometry (LC-MS) for quantitation. The chromatographic separation was performed on ODS-3 column using the isocratic mixture of 0.01 mM acetic acid in 0.2% aqueous solution of formic acid at a flow rate of 0.6 ml/min at 25 degrees C. The recoveries of acrylamide from potato chips, biscuits and coffee ranged between 92.8 and 101.5% with relative standard deviations of 4.1% or less. The limit of detection (LOD) and the limit of quantitation (LOQ) were 2 ng/g and 6 ng/g in the basis of signal to noise ratios of 3:1 and 9:1, respectively.

  18. Eliminating the η-problem in SUGRA hybrid inflation with vector backreaction

    NASA Astrophysics Data System (ADS)

    Dimopoulos, Konstantinos; Lazarides, George; Wagstaff, Jacques M.

    2012-02-01

    It is shown that, when the inflaton field modulates the gauge kinetic function of the gauge fields in supergravity realisations of inflation, the dynamic backreaction leads to a new inflationary attractor solution, in which the inflaton's variation suffers additional impedance. As a result, slow-roll inflation can naturally occur along directions of the scalar potential which would be too steep and curved to support it otherwise. This provides a generic solution to the infamous eta-problem of inflation in supergravity. Moreover, it is shown that, in the new inflationary attractor, the spectral index of the generated curvature perturbations is kept mildly red despite eta of order unity. The above findings are applied to a model of hybrid inflation in supergravity with a generic Kähler potential. The spectral index of the generated curvature perturbations is found to be 0.97-0.98, in excellent agreement with observations. The gauge field can play the role of the vector curvaton after inflation but observable statistical anisotropy requires substantial tuning of the gauge coupling.

  19. Selective Transfer Machine for Personalized Facial Expression Analysis

    PubMed Central

    Chu, Wen-Sheng; De la Torre, Fernando; Cohn, Jeffrey F.

    2017-01-01

    Automatic facial action unit (AU) and expression detection from videos is a long-standing problem. The problem is challenging in part because classifiers must generalize to previously unknown subjects that differ markedly in behavior and facial morphology (e.g., heavy versus delicate brows, smooth versus deeply etched wrinkles) from those on which the classifiers are trained. While some progress has been achieved through improvements in choices of features and classifiers, the challenge occasioned by individual differences among people remains. Person-specific classifiers would be a possible solution but for a paucity of training data. Sufficient training data for person-specific classifiers typically is unavailable. This paper addresses the problem of how to personalize a generic classifier without additional labels from the test subject. We propose a transductive learning method, which we refer as a Selective Transfer Machine (STM), to personalize a generic classifier by attenuating person-specific mismatches. STM achieves this effect by simultaneously learning a classifier and re-weighting the training samples that are most relevant to the test subject. We compared STM to both generic classifiers and cross-domain learning methods on four benchmarks: CK+ [44], GEMEP-FERA [67], RU-FACS [4] and GFT [57]. STM outperformed generic classifiers in all. PMID:28113267

  20. Spontaneous symmetry breaking in active droplets provides a generic route to motility

    PubMed Central

    Tjhung, Elsen; Marenduzzo, Davide; Cates, Michael E.

    2012-01-01

    We explore a generic mechanism whereby a droplet of active matter acquires motility by the spontaneous breakdown of a discrete symmetry. The model we study offers a simple representation of a “cell extract” comprising, e.g., a droplet of actomyosin solution. (Such extracts are used experimentally to model the cytoskeleton). Actomyosin is an active gel whose polarity describes the mean sense of alignment of actin fibres. In the absence of polymerization and depolymerization processes (‘treadmilling’), the gel’s dynamics arises solely from the contractile motion of myosin motors; this should be unchanged when polarity is inverted. Our results suggest that motility can arise in the absence of treadmilling, by spontaneous symmetry breaking (SSB) of polarity inversion symmetry. Adapting our model to wall-bound cells in two dimensions, we find that as wall friction is reduced, treadmilling-induced motility falls but SSB-mediated motility rises. The latter might therefore be crucial in three dimensions where frictional forces are likely to be modest. At a supracellular level, the same generic mechanism can impart motility to aggregates of nonmotile but active bacteria; we show that SSB in this (extensile) case leads generically to rotational as well as translational motion. PMID:22797894

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