Sample records for dr research reactors

  1. Advanced Instrumentation and Control Methods for Small and Medium Reactors with IRIS Demonstration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J. Wesley Hines; Belle R. Upadhyaya; J. Michael Doster

    2011-05-31

    Development and deployment of small-scale nuclear power reactors and their maintenance, monitoring, and control are part of the mission under the Small Modular Reactor (SMR) program. The objectives of this NERI-consortium research project are to investigate, develop, and validate advanced methods for sensing, controlling, monitoring, diagnosis, and prognosis of these reactors, and to demonstrate the methods with application to one of the proposed integral pressurized water reactors (IPWR). For this project, the IPWR design by Westinghouse, the International Reactor Secure and Innovative (IRIS), has been used to demonstrate the techniques developed under this project. The research focuses on three topicalmore » areas with the following objectives. Objective 1 - Develop and apply simulation capabilities and sensitivity/uncertainty analysis methods to address sensor deployment analysis and small grid stability issues. Objective 2 - Develop and test an autonomous and fault-tolerant control architecture and apply to the IRIS system and an experimental flow control loop, with extensions to multiple reactor modules, nuclear desalination, and optimal sensor placement strategy. Objective 3 - Develop and test an integrated monitoring, diagnosis, and prognosis system for SMRs using the IRIS as a test platform, and integrate process and equipment monitoring (PEM) and process and equipment prognostics (PEP) toolboxes. The research tasks are focused on meeting the unique needs of reactors that may be deployed to remote locations or to developing countries with limited support infrastructure. These applications will require smaller, robust reactor designs with advanced technologies for sensors, instrumentation, and control. An excellent overview of SMRs is described in an article by Ingersoll (2009). The article refers to these as deliberately small reactors. Most of these have modular characteristics, with multiple units deployed at the same plant site. Additionally, the topics focus on meeting two of the eight needs outlined in the recently published 'Technology Roadmap on Instrumentation, Control, and Human-Machine Interface (ICHMI) to Support DOE Advanced Nuclear Energy Programs' which was created 'to provide a systematic path forward for the integration of new ICHMI technologies in both near-term and future nuclear power plants and the reinvigoration of the U.S. nuclear ICHMI community and capabilities.' The research consortium is led by The University of Tennessee (UT) and is focused on three interrelated topics: Topic 1 (simulator development and measurement sensitivity analysis) is led by Dr. Mike Doster with Dr. Paul Turinsky of North Carolina State University (NCSU). Topic 2 (multivariate autonomous control of modular reactors) is led by Dr. Belle Upadhyaya of the University of Tennessee (UT) and Dr. Robert Edwards of Penn State University (PSU). Topic 3 (monitoring, diagnostics, and prognostics system development) is led by Dr. Wes Hines of UT. Additionally, South Carolina State University (SCSU, Dr. Ken Lewis) participated in this research through summer interns, visiting faculty, and on-campus research projects identified throughout the grant period. Lastly, Westinghouse Science and Technology Center (Dr. Mario Carelli) was a no-cost collaborator and provided design information related to the IRIS demonstration platform and defining needs that may be common to other SMR designs. The results of this research are reported in a six-volume Final Report (including the Executive Summary, Volume 1). Volumes 2 through 6 of the report describe in detail the research and development under the topical areas. This volume serves to introduce the overall NERI-C project and to summarize the key results. Section 2 provides a summary of the significant contributions of this project. A list of all the publications under this project is also given in Section 2. Section 3 provides a brief summary of each of the five volumes (2-6) of the report. The contributions of SCSU are described in Section 4, including a summary of undergraduate research experience. The project management organizational chart is provided as Figure 1. Appendices A, B, and C contain the reports on the summer research performed at the University of Tennessee by undergraduate students from South Carolina State University.« less

  2. Energy Innovation Hubs: A Home for Scientific Collaboration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chu, Steven

    Secretary Chu will host a live, streaming Q&A session with the directors of the Energy Innovation Hubs on Tuesday, March 6, at 2:15 p.m. EST. The directors will be available for questions regarding their teams' work and the future of American energy. Ask your questions in the comments below, or submit them on Facebook, Twitter (@energy), or send an e-mail to newmedia@hq.doe.gov, prior or during the live event. Dr. Hank Foley is the director of the Greater Philadelphia Innovation Cluster for Energy-Efficient Buildings, which is pioneering new data intensive techniques for designing and operating energy efficient buildings, including advanced computermore » modeling. Dr. Douglas Kothe is the director of the Consortium for Advanced Simulation of Light Water Reactors, which uses powerful supercomputers to create "virtual" reactors that will help improve the safety and performance of both existing and new nuclear reactors. Dr. Nathan Lewis is the director of the Joint Center for Artificial Photosynthesis, which focuses on how to produce fuels from sunlight, water, and carbon dioxide. The Energy Innovation Hubs are major integrated research centers, with researchers from many different institutions and technical backgrounds. Each hub is focused on a specific high priority goal, rapidly accelerating scientific discoveries and shortening the path from laboratory innovation to technological development and commercial deployment of critical energy technologies. Ask your questions in the comments below, or submit them on Facebook, Twitter (@energy), or send an e-mail to newmedia@energy.gov, prior or during the live event. The Energy Innovation Hubs are major integrated research centers, with researchers from many different institutions and technical backgrounds. Each Hub is focused on a specific high priority goal, rapidly accelerating scientific discoveries and shortening the path from laboratory innovation to technological development and commercial deployment of critical energy technologies. Dr. Hank Holey is the director of the Greater Philadelphia Innovation Cluster for Energy-Efficient Buildings, which is pioneering new data intensive techniques for designing and operating energy efficient buildings, including advanced computer modeling. Dr. Douglas Kothe is the director of the Modeling and Simulation for Nuclear Reactors Hub, which uses powerful supercomputers to create "virtual" reactors that will help improve the safety and performance of both existing and new nuclear reactors. Dr. Nathan Lewis is the director of the Joint Center for Artificial Photosynthesis Hub, which focuses on how to produce biofuels from sunlight, water, and carbon dioxide.« less

  3. Energy Innovation Hubs: A Home for Scientific Collaboration

    ScienceCinema

    Chu, Steven

    2017-12-11

    Secretary Chu will host a live, streaming Q&A session with the directors of the Energy Innovation Hubs on Tuesday, March 6, at 2:15 p.m. EST. The directors will be available for questions regarding their teams' work and the future of American energy. Ask your questions in the comments below, or submit them on Facebook, Twitter (@energy), or send an e-mail to newmedia@hq.doe.gov, prior or during the live event. Dr. Hank Foley is the director of the Greater Philadelphia Innovation Cluster for Energy-Efficient Buildings, which is pioneering new data intensive techniques for designing and operating energy efficient buildings, including advanced computer modeling. Dr. Douglas Kothe is the director of the Consortium for Advanced Simulation of Light Water Reactors, which uses powerful supercomputers to create "virtual" reactors that will help improve the safety and performance of both existing and new nuclear reactors. Dr. Nathan Lewis is the director of the Joint Center for Artificial Photosynthesis, which focuses on how to produce fuels from sunlight, water, and carbon dioxide. The Energy Innovation Hubs are major integrated research centers, with researchers from many different institutions and technical backgrounds. Each hub is focused on a specific high priority goal, rapidly accelerating scientific discoveries and shortening the path from laboratory innovation to technological development and commercial deployment of critical energy technologies. Ask your questions in the comments below, or submit them on Facebook, Twitter (@energy), or send an e-mail to newmedia@energy.gov, prior or during the live event. The Energy Innovation Hubs are major integrated research centers, with researchers from many different institutions and technical backgrounds. Each Hub is focused on a specific high priority goal, rapidly accelerating scientific discoveries and shortening the path from laboratory innovation to technological development and commercial deployment of critical energy technologies. Dr. Hank Holey is the director of the Greater Philadelphia Innovation Cluster for Energy-Efficient Buildings, which is pioneering new data intensive techniques for designing and operating energy efficient buildings, including advanced computer modeling. Dr. Douglas Kothe is the director of the Modeling and Simulation for Nuclear Reactors Hub, which uses powerful supercomputers to create "virtual" reactors that will help improve the safety and performance of both existing and new nuclear reactors. Dr. Nathan Lewis is the director of the Joint Center for Artificial Photosynthesis Hub, which focuses on how to produce biofuels from sunlight, water, and carbon dioxide.

  4. Thermal-Hydraulic Design of a Fluoride High-Temperature Demonstration Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carbajo, Juan J; Qualls, A L

    2016-01-01

    INTRODUCTION The Fluoride High-Temperature Reactor (FHR) named the Demonstration Reactor (DR) is a novel reactor concept using molten salt coolant and TRIstructural ISOtropic (TRISO) fuel that is being developed at Oak Ridge National Laboratory (ORNL). The objective of the FHR DR is to advance the technology readiness level of FHRs. The FHR DR will demonstrate technologies needed to close remaining gaps to commercial viability. The FHR DR has a thermal power of 100 MWt, very similar to the SmAHTR, another FHR ORNL concept (Refs. 1 and 2) with a power of 125 MWt. The FHR DR is also a smallmore » version of the Advanced High Temperature Reactor (AHTR), with a power of 3400 MWt, cooled by a molten salt and also being developed at ORNL (Ref. 3). The FHR DR combines three existing technologies: (1) high-temperature, low-pressure molten salt coolant, (2) high-temperature coated-particle TRISO fuel, (3) and passive decay heat cooling systems by using Direct Reactor Auxiliary Cooling Systems (DRACS). This paper presents FHR DR thermal-hydraulic design calculations.« less

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qualls, A. L.; Brown, Nicholas R.; Betzler, Benjamin R.

    The fluoride salt-cooled high-temperature reactor (FHR) demonstration reactor (DR) is a concept for a salt-cooled reactor with 100 megawatts of thermal output (MWt). It would use tristructural-isotropic (TRISO) particle fuel within prismatic graphite blocks. FLiBe (2 LiF-BeF 2) is the reference primary coolant. The FHR DR is designed to be small, simple, and affordable. Development of the FHR DR is a necessary intermediate step to enable near-term commercial FHRs. Lower risk technologies are purposely included in the initial FHR DR design to ensure that the reactor can be built, licensed, and operated within an acceptable budget and schedule. These technologiesmore » include TRISO particle fuel, replaceable core structural material, the use of that same material for the primary and intermediate loops, and tube-and-shell primary-to-intermediate heat exchangers. Several preconceptual and conceptual design efforts that have been conducted on FHR concepts bear a significant influence on the FHR DR design. Specific designs include the Oak Ridge National Laboratory (ORNL) advanced high-temperature reactor (AHTR) with 3400/1500 MWt/megawatts of electric output (MWe), as well as a 125 MWt small modular AHTR (SmAHTR) from ORNL. Other important examples are the Mk1 pebble bed FHR (PB-FHR) concept from the University of California, Berkeley (UCB), and an FHR test reactor design developed at the Massachusetts Institute of Technology (MIT). The MIT FHR test reactor is based on a prismatic fuel platform and is directly relevant to the present FHR DR design effort. These FHR concepts are based on reasonable assumptions for credible commercial prototypes. The FHR DR concept also directly benefits from the operating experience of the Molten Salt Reactor Experiment (MSRE), as well as the detailed design efforts for a large molten salt reactor concept and its breeder variant, the Molten Salt Breeder Reactor. The FHR DR technology is most representative of the 3400 MWt AHTR concept, and it will demonstrate key operational features of that design. The FHR DR will be closely scaled to the SmAHTR concept in power and flows, so any technologies demonstrated will be directly applicable to a reactor concept of that size. The FHR DR is not a commercial prototype design, but rather a DR that serves a cost and risk mitigation function for a later commercial prototype. It is expected to have a limited operational lifetime compared to a commercial plant. It is designed to be a low-cost reactor compared to more mature advanced prototype DRs. A primary reason to build the FHR DR is to learn about salt reactor technologies and demonstrate solutions to remaining technical gaps.« less

  6. Preconceptual design of a fluoride high temperature salt-cooled engineering demonstration reactor: Motivation and overview

    DOE PAGES

    Qualls, A. Louis; Betzler, Benjamin R.; Brown, Nicholas R.; ...

    2016-12-21

    Engineering demonstration reactors are nuclear reactors built to establish proof of concept for technology options that have never been built. Examples of engineering demonstration reactors include Peach Bottom 1 for high temperature gas-cooled reactors (HTGRs) and Experimental Breeder Reactor-II (EBR-II) for sodium-cooled fast reactors. Historically, engineering demonstrations have played a vital role in advancing the technology readiness level of reactor technologies. Our paper details a preconceptual design for a fluoride salt-cooled engineering demonstration reactor. The fluoride salt-cooled high-temperature reactor (FHR) demonstration reactor (DR) is a concept for a salt-cooled reactor with 100 megawatts of thermal output (MWt). It would usemore » tristructural-isotropic (TRISO) particle fuel within prismatic graphite blocks. FLiBe (2 7LiF-BeF2) is the reference primary coolant. The FHR DR is designed to be small, simple, and affordable. Development of the FHR DR is a necessary intermediate step to enable near-term commercial FHRs. The design philosophy of the FHR DR was focused on safety, near-term deployment, and flexibility. Lower risk technologies are purposely included in the initial FHR DR design to ensure that the reactor can be built, licensed, and operated as an engineering demonstration with minimal risk and cost. These technologies include TRISO particle fuel, replaceable core structures, and consistent structural material selection for core structures and the primary and intermediate loops, and tube-and-shell primary-to-intermediate heat exchangers. Important capabilities to be demonstrated by building and operating the FHR DR include fabrication and operation of high temperature reactors; heat exchanger performance (including passive decay heat removal); pump performance; and reactivity control; salt chemistry control to maximize vessel life; tritium management; core design methodologies; salt procurement, handling, maintenance and ultimate disposal. It is recognized that non-nuclear separate and integral test efforts (e.g., heated salt loops or loops using simulant fluids) are necessary to develop the technologies that will be demonstrated in the FHR DR.« less

  7. Preconceptual design of a fluoride high temperature salt-cooled engineering demonstration reactor: Motivation and overview

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qualls, A. Louis; Betzler, Benjamin R.; Brown, Nicholas R.

    Engineering demonstration reactors are nuclear reactors built to establish proof of concept for technology options that have never been built. Examples of engineering demonstration reactors include Peach Bottom 1 for high temperature gas-cooled reactors (HTGRs) and Experimental Breeder Reactor-II (EBR-II) for sodium-cooled fast reactors. Historically, engineering demonstrations have played a vital role in advancing the technology readiness level of reactor technologies. Our paper details a preconceptual design for a fluoride salt-cooled engineering demonstration reactor. The fluoride salt-cooled high-temperature reactor (FHR) demonstration reactor (DR) is a concept for a salt-cooled reactor with 100 megawatts of thermal output (MWt). It would usemore » tristructural-isotropic (TRISO) particle fuel within prismatic graphite blocks. FLiBe (2 7LiF-BeF2) is the reference primary coolant. The FHR DR is designed to be small, simple, and affordable. Development of the FHR DR is a necessary intermediate step to enable near-term commercial FHRs. The design philosophy of the FHR DR was focused on safety, near-term deployment, and flexibility. Lower risk technologies are purposely included in the initial FHR DR design to ensure that the reactor can be built, licensed, and operated as an engineering demonstration with minimal risk and cost. These technologies include TRISO particle fuel, replaceable core structures, and consistent structural material selection for core structures and the primary and intermediate loops, and tube-and-shell primary-to-intermediate heat exchangers. Important capabilities to be demonstrated by building and operating the FHR DR include fabrication and operation of high temperature reactors; heat exchanger performance (including passive decay heat removal); pump performance; and reactivity control; salt chemistry control to maximize vessel life; tritium management; core design methodologies; salt procurement, handling, maintenance and ultimate disposal. It is recognized that non-nuclear separate and integral test efforts (e.g., heated salt loops or loops using simulant fluids) are necessary to develop the technologies that will be demonstrated in the FHR DR.« less

  8. Core Design Characteristics of the Fluoride Salt-Cooled High Temperature Demonstration Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Nicholas R; Qualls, A L; Betzler, Benjamin R

    2016-01-01

    Fluoride salt-cooled high temperature reactors (FHRs) are a promising reactor technology option with significant knowledge gaps to implementation. One potential approach to address those technology gaps is via a small-scale demonstration reactor with the goal of increasing the technology readiness level (TRL) of the overall system for the longer term. The objective of this paper is to outline a notional concept for such a system, and to address how the proposed concept would advance the TRL of FHR concepts. Development of the proposed FHR Demonstration Reactor (DR) will enable commercial FHR deployment through disruptive and rapid technology development and demonstration.more » The FHR DR will close remaining gaps to commercial viability. Lower risk technologies are included in the initial FHR DR design to ensure that the reactor can be built, licensed, and operated within an acceptable budget and schedule. Important capabilities that will be demonstrated by building and operating the FHR DR include core design methodologies; fabrication and operation of high temperature reactors; salt procurement, handling, maintenance, and ultimate disposal; salt chemistry control to maximize vessel life; tritium management; heat exchanger performance; pump performance; and reactivity control. The FHR DR is considered part of a broader set of FHR technology development and demonstration efforts, some of which are already underway. Nonreactor test efforts (e.g., heated salt loops or loops using simulant fluids) can demonstrate many technologies necessary for commercial deployment of FHRs. The FHR DR, however, fulfills a crucial role in FHR technology development by advancing the technical maturity and readiness level of the system as a whole.« less

  9. Final report, PT IP-535-C: Test of smaller VSR`s in DR reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vaughn, A.D.

    1963-04-17

    Because of rod-sticking problems at DR Reactor, a knuckle rod of B Reactor design was installed in vertical safety channel number 28. The substitute VSR, which has a smaller diameter than the original DR rod, has been tested for its operational feasibility including both drop time and reactivity effect. The reactivity effect of the rod was estimated by comparison of the reactivity transient caused by insertion of the specific B-type rod after scramming into the pile, with similar transients caused by normal vertical safety rod in an adjacent channel. This document lists the indicated relative control strength of the rodmore » as an empirical basis for future safety calculations. Results indicate that the B-type knuckel rod in DR reactor is about 80% as strong as a normal DR vertical safety rod if used in equivalent flux distribution and location; this makes it reasonable to assume that the local control strength of the B-type knuckel rod is 98 {mu}b.« less

  10. DR Reactor VSR channel damage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kempf, F.J.; Rawlins, J.K.

    1961-10-30

    On July 11, 1961 the Ball 3X System at DR Reactor was inadventently tripped. All vertical safety rods dropped and all channels were filled with balls. This report has the twofold purpose of documenting borescope observations of ten vertical rod channels at DR Reactor and recording the estimated extent of graphite damage resulting from the above incident. Channel damage data are presented on appended drawings. With suitable notations, the tracings of these drawings may be revised to reflect any future graphite damage. All vertical rod channels at DR Reactor were visually examined with a closed circuit television system during ballmore » removal efforts. Typical photographs of trapped balls and ledges, as viewed on the television monitor, are shown. Photographs of typical graphite damage, obtained through the borescope are also included in this report. 3 refs., 8 figs., 1 tab.« less

  11. SNAP (Space Nuclear Auxiliary Power) reactor overview. Final report, June 1982-December 1983

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Voss, S.S.

    1984-08-01

    The SNAP reactor programs are outlined in this report. A summary of the program is included along with a technical outline of the SER, S2DR, SNAP 10A/SNAPSHOT, S8ER, and S8DR reactor systems. Specifications of the designs, the design logic and a conclusion outlining some of the program weaknesses are given.

  12. Leak-Before-Break: Further developments in regulatory policies and supporting research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilkowski, G.M.; Chao, K.-S.

    1990-02-01

    The fourth in a series of international Leak-Before-Break (LBB) Seminars supported in part by the US Nuclear Regulatory Commission was held at the National Central Library in Taipei, Taiwan on May 11 and 12, 1989. The seminar updated the international polices and supporting research on LBB. Attendees included representatives from regulatory agencies, electric utilities, nuclear power plant fabricators, research organizations, and academic institutions. Regulatory policy was the subject of presentations by Mr. G. Arlotto (US NRC, USA) Dr. B. Jarman (AECB, Canada), Dr.P. Milella (ENEA-DISP, Italy), Dr. C. Faidy (EDF/Septen, France ), and Dr. K. Takumi (NUPEC, Japan). A papermore » by Mr. K. Wichman and Mr. A. Lee of the US NRC Office of Nuclear Reactor Regulation is included as background material to these proceedings; it discusses the history and status of LBB applications in US nuclear power plants. In addition, several papers on the supporting research programs described regulatory policy or industry standards for flaw evaluations, e.g., the ASME Section XI code procedures. Supporting research programs were reviewed on the first and second day by several participants from Taiwan, US, Japan, Canada, Italy, and France. Each individual paper has been cataloged separately.« less

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koch, Len; Agnew, Harold

    Dr. Harold Agnew, retired director of Los Alamos National Laboratory and one of 49 people present on December 2, 1942 when the world’s first man-made controlled nuclear chain reaction was achieved with the CP-1 reactor, and Dr. Len Koch, one of Argonne’s earliest staff members and a designer of EBR-I, the first liquid metal-cooled fast reactor, spoke about their early work during “The Dawn of the Nuclear Age”, a Director’s Special Symposium held as one of the events to commemorate the 70th anniversary year of CP-1 achieving criticality. The symposium was moderated by Dr. Charles Till, a retired Argonne associatemore » laboratory director who led Argonne’s nuclear engineering programs throughout the 1980’s and ‘90’s. Dr. Agnew painted a vivid picture of the challenges and rewards of working in Enrico Fermi’s group under strict security conditions and the complete faith all in the group had in Fermi’s analyses. He stated that no one ever doubted that CP-1 would achieve criticality, and when the moment came, those present acknowledged the accomplishment with little more than a subdued toast of chianti from a bottle provided by reactor physicist Eugene Wigner. This experimental work on nuclear reactors was continued in the Chicago area and led first by Fermi and then Walter Zinn, another member of Fermi’s CP-1 group, resulting in the formal establishment of Argonne National Laboratory on July 1, 1946. Dr. Koch described how much he enjoyed working at Argonne through the 1950’s and ‘60’s and contributing to many of the research “firsts” that Argonne achieved in the nuclear energy field and led to the foundation of the commercial nuclear power generation industry. His reminiscences about all that was achieved with EBR-I and how that work then led into Argonne’s design, building, and operation of EBR-II as a full demonstration of a fast reactor power plant brought Argonne’s nuclear energy legacy to life for everyone in the auditorium. These engaging presentations prompted a number of questions from the audience, which showed its appreciation for both speakers by ending the symposium with a standing ovation.« less

  14. CP-1 70th Anniversary Symposium

    ScienceCinema

    Len Koch; Harold Agnew

    2017-12-09

    Dr. Harold Agnew, retired director of Los Alamos National Laboratory and one of 49 people present on December 2, 1942 when the world’s first man-made controlled nuclear chain reaction was achieved with the CP-1 reactor, and Dr. Len Koch, one of Argonne’s earliest staff members and a designer of EBR-I, the first liquid metal-cooled fast reactor, spoke about their early work during “The Dawn of the Nuclear Age”, a Director’s Special Symposium held as one of the events to commemorate the 70th anniversary year of CP-1 achieving criticality. The symposium was moderated by Dr. Charles Till, a retired Argonne associate laboratory director who led Argonne’s nuclear engineering programs throughout the 1980’s and ‘90’s. Dr. Agnew painted a vivid picture of the challenges and rewards of working in Enrico Fermi’s group under strict security conditions and the complete faith all in the group had in Fermi’s analyses. He stated that no one ever doubted that CP-1 would achieve criticality, and when the moment came, those present acknowledged the accomplishment with little more than a subdued toast of chianti from a bottle provided by reactor physicist Eugene Wigner. This experimental work on nuclear reactors was continued in the Chicago area and led first by Fermi and then Walter Zinn, another member of Fermi’s CP-1 group, resulting in the formal establishment of Argonne National Laboratory on July 1, 1946. Dr. Koch described how much he enjoyed working at Argonne through the 1950’s and ‘60’s and contributing to many of the research “firsts” that Argonne achieved in the nuclear energy field and led to the foundation of the commercial nuclear power generation industry. His reminiscences about all that was achieved with EBR-I and how that work then led into Argonne’s design, building, and operation of EBR-II as a full demonstration of a fast reactor power plant brought Argonne’s nuclear energy legacy to life for everyone in the auditorium. These engaging presentations prompted a number of questions from the audience, which showed its appreciation for both speakers by ending the symposium with a standing ovation.

  15. Nuclear Reactor Physics

    NASA Astrophysics Data System (ADS)

    Stacey, Weston M.

    2001-02-01

    An authoritative textbook and up-to-date professional's guide to basic and advanced principles and practices Nuclear reactors now account for a significant portion of the electrical power generated worldwide. At the same time, the past few decades have seen an ever-increasing number of industrial, medical, military, and research applications for nuclear reactors. Nuclear reactor physics is the core discipline of nuclear engineering, and as the first comprehensive textbook and reference on basic and advanced nuclear reactor physics to appear in a quarter century, this book fills a large gap in the professional literature. Nuclear Reactor Physics is a textbook for students new to the subject, for others who need a basic understanding of how nuclear reactors work, as well as for those who are, or wish to become, specialists in nuclear reactor physics and reactor physics computations. It is also a valuable resource for engineers responsible for the operation of nuclear reactors. Dr. Weston Stacey begins with clear presentations of the basic physical principles, nuclear data, and computational methodology needed to understand both the static and dynamic behaviors of nuclear reactors. This is followed by in-depth discussions of advanced concepts, including extensive treatment of neutron transport computational methods. As an aid to comprehension and quick mastery of computational skills, he provides numerous examples illustrating step-by-step procedures for performing the calculations described and chapter-end problems. Nuclear Reactor Physics is a useful textbook and working reference. It is an excellent self-teaching guide for research scientists, engineers, and technicians involved in industrial, research, and military applications of nuclear reactors, as well as government regulators who wish to increase their understanding of nuclear reactors.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Craig, D.F.

    The division was formed in 1946 at the suggestion of Dr. Eugene P. Wigner to attack the problem of the distortion of graphite in the early reactors due to exposure to reactor neutrons, and the consequent radiation damage. It was called the Metallurgy Division and assembled the metallurgical and solid state physics activities of the time which were not directly related to nuclear weapons production. William A. Johnson, a Westinghouse employee, was named Division Director in 1946. In 1949 he was replaced by John H Frye Jr. when the Division consisted of 45 people. He was director during most ofmore » what is called the Reactor Project Years until 1973 and his retirement. During this period the Division evolved into three organizational areas: basic research, applied research in nuclear reactor materials, and reactor programs directly related to a specific reactor(s) being designed or built. The Division (Metals and Ceramics) consisted of 204 staff members in 1973 when James R. Weir, Jr., became Director. This was the period of the oil embargo, the formation of the Energy Research and Development Administration (ERDA) by combining the Atomic Energy Commission (AEC) with the Office of Coal Research, and subsequent formation of the Department of Energy (DOE). The diversification process continued when James O. Stiegler became Director in 1984, partially as a result of the pressure of legislation encouraging the national laboratories to work with U.S. industries on their problems. During that time the Division staff grew from 265 to 330. Douglas F. Craig became Director in 1992.« less

  17. 74. ARAII. Dr. William Zinn of combustion engineering company and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    74. ARA-II. Dr. William Zinn of combustion engineering company and others at controls of SL-1. August 8, 1959. Ineel photo no. 59-4109. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  18. Research and Development of Multiphysics Models in Support of the Conversion of the High Flux Isotope Reactor to Low Enriched Uranium Fuel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bodey, Isaac T.; Curtis, Franklin G.; Arimilli, Rao V.

    The findings presented in this report are results of a five year effort led by the RRD Division of the ORNL, which is focused on research and development toward the conversion of the High Flux Isotope Reactor (HFIR) fuel from high-enriched uranium (HEU) to low-enriched uranium (LEU). This report focuses on the tasks accomplished by the University of Tennessee Knoxville (UTK) team from the Department of Mechanical, Aerospace, and Biomedical Engineering (MABE) that provided expert support in multiphysics modeling of complex problems associated with the LEU conversion of the HFIR reactor. The COMSOL software was used as the main computationalmore » modeling tool, whereas Solidworks was also used in support of computer-aided-design (CAD) modeling of the proposed LEU fuel design. The UTK research has been governed by a statement of work (SOW), which was updated annually to clearly define the specific tasks reported herein. Ph.D. student Isaac T. Bodey has focused on heat transfer and fluid flow modeling issues and has been aided by his major professor Dr. Rao V. Arimilli. Ph.D. student Franklin G. Curtis has been focusing on modeling the fluid-structure interaction (FSI) phenomena caused by the mechanical forces acting on the fuel plates, which in turn affect the fluid flow in between the fuel plates, and ultimately the heat transfer, is also affected by the FSI changes. Franklin Curtis has been aided by his major professor Dr. Kivanc Ekici. M.Sc. student Adam R. Travis has focused two major areas of research: (1) on accurate CAD modeling of the proposed LEU plate design, and (2) reduction of the model complexity and dimensionality through interdimensional coupling of the fluid flow and heat transfer for the HFIR plate geometry. Adam Travis is also aided by his major professor, Dr. Kivanc Ekici. We must note that the UTK team, and particularly the graduate students, have been in very close collaboration with Dr. James D. Freels (ORNL technical monitor and mentor) and have benefited greatly from his leadership and expertise in COMSOL modeling of complex physical phenomena. Both UTK and ORNL teams have used COMSOL releases 3.4 through 5.0 inclusive (with particular emphasis on 3.5a, 4.3a, 4.3b, and 4.4) for most of the work described in this report, except where stated otherwise. Just as in the performance of the research, each of the respective sections has been originally authored by respective authors. Therefore, the reader will observe a contrast in writing style throughout this document.« less

  19. An Approach for Assessing Development and Deployment Risks in the DOE Fuel Cycle Options Evaluation and Screening Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gehin, Jess C; Oakley, Brian; Worrall, Andrew

    2015-01-01

    Abstract One of the key objectives of the U.S. Department of Energy (DOE) Nuclear Energy R&D Roadmap is the development of sustainable nuclear fuel cycles that can improve natural resource utilization and provide solutions to the management of nuclear wastes. Recently, an evaluation and screening (E&S) of fuel cycle systems has been conducted to identify those options that provide the best opportunities for obtaining such improvements and also to identify the required research and development activities that can support the development of advanced fuel cycle options. In order to evaluate and screen the E&S study included nine criteria including Developmentmore » and Deployment Risk (D&DR). More specifically, this criterion was represented by the following metrics: Development time, development cost, deployment cost from prototypic validation to first-of-a-kind commercial, compatibility with the existing infrastructure, existence of regulations for the fuel cycle and familiarity with licensing, and existence of market incentives and/or barriers to commercial implementation of fuel cycle processes. Given the comprehensive nature of the study, a systematic approach was needed to determine metric data for the D&DR criterion, and is presented here. As would be expected, the Evaluation Group representing the once-through use of uranium in thermal reactors is always the highest ranked fuel cycle Evaluation Group for this D&DR criterion. Evaluation Groups that consist of once-through fuel cycles that use existing reactor types are consistently ranked very high. The highest ranked limited and continuous recycle fuel cycle Evaluation Groups are those that recycle Pu in thermal reactors. The lowest ranked fuel cycles are predominately continuous recycle single stage and multi-stage fuel cycles that involve TRU and/or U-233 recycle.« less

  20. LCRE and SNAP 50-DR-1 programs. Engineering progress report, October 1, 1962--December 31, 1962

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Declassified 5 Sep 1973. Information is presented concerning LCRE specifications, reactor kinetics, fuel elements, primary coolant circuit, secondary coolant circuit, materials development, and fabrication; and SNAP50-DR- 1 specifications, primary pump, and materials development. (DCC)

  1. Biological Investigation of the Stimulated Flapping Motions of the Moth, Manduca sexta

    DTIC Science & Technology

    2011-03-01

    the sites of toxic chemical spills or damaged nuclear reactors (Alexander, 2002). Dr. Mark Reeder, Editor-in-Chief of the International Journal...Process The overall objective of research, using bio -inspired technology and techniques, is to develop clear scientific understanding about some of...it in a small container and submerging it in a bucket of ice for approximately 15 minutes, until the moth was unresponsive to stimulation.  Under

  2. Laser Assisted CVD Growth of A1N and GaN

    DTIC Science & Technology

    1990-08-31

    additional cost sharing. RESEARCH FACILITIES The york is being performed in the Howard University Laser Laboratory. This is a free-standing buildinq...would be used to optimize computer models of the laser induced CVD reactor. FACILITIES AND EQUIPMENT - ADDITIONAL COST SHARING This year Howard ... University has provided $45,000 for the purchase of an excimer laser to be shared by Dr. Crye for the diode laser probe experiments and another Assistant

  3. Biotechnica 󈨙 International Congress for Biotechnology Held in Hannover, Germany, D.R. on 8-10 October 1985,

    DTIC Science & Technology

    1986-02-27

    Cross flow Filtration gelfiltratoi- Sjir.N dvng flttration filtration - Partition ad rlipon - - P trec pilaton Figure I. Downstream processing of...transformation the Nuclear Research Center, Jilich, into the L-amino acid is achieved in an West Germany. Until now the degrading enzyme reactor. This time...Some enzymatic processes can be car- of a hydrolase is the use of a peptidase tied out on a practical scale only in to produce peptides. One route to

  4. Mission Specialist (MS) Ride with tool tray on middeck

    NASA Image and Video Library

    1983-06-24

    STS007-12-536 (18-24 June 1983) --- Astronaut Sally K. Ride, STS-7 mission specialist, displays the array of tools at her disposal on the mid deck of the Earth-orbiting Space Shuttle Challenger. Dr. Ride is positioned near the monodisperse latex reactor (MLR) experiment. They cylinder near her elbow is the actual reactor and the device next to it at right frame edge is the MRL apparatus container. Dr. Ride and four other astronauts are sharing duties aboard the reusable spacecraft for a six-day space mission full of “firsts.” This photograph was made with a 35mm camera. It was among the visuals used by crewmembers at their post-flight press conference.

  5. Dissociative Recombination of FeO(+) with Electrons: Implications for Plasma Layers in the Ionosphere.

    PubMed

    Bones, D L; Plane, J M C; Feng, W

    2016-03-10

    The dissociative recombination (DR) of FeO(+) ions with electrons has been studied in a flowing afterglow reactor. FeO(+) was generated by the pulsed laser ablation of a solid Fe target, and then entrained in an Ar(+) ion/electron plasma where the absolute electron density was measured using a Langmuir probe. A kinetic model describing gas-phase chemistry and diffusion to the reactor walls was fitted to the experimental data, yielding a DR rate coefficient at 298 K of k(FeO(+) + e(-)) = (5.5 ± 1.0) × 10(-7) cm(3) molecule(-1) s(-1), where the quoted uncertainty is at the 2σ level. Fe(+) ions in the lower thermosphere are oxidized by O3 to FeO(+), and this DR reaction is shown to provide a more important route for neutralizing Fe(+) below 110 km than the radiative/dielectronic recombination of Fe(+) with electrons. The experimental system was first validated by measuring two other DR reaction rate coefficients: k(O2(+) + e(-)) = (2.0 ± 0.4) × 10(-7) and k(N2O(+) + e(-)) = (3.3 ± 0.8) × 10(-7) cm(3) molecule(-1) s(-1), which are in good agreement with the recent literature.

  6. The Endurance Bioenergy Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Laible, Philip; Michaund, Matt

    2012-07-03

    Argonne biophysicist Dr. Philip Laible and Air Force Major Matt Michaud talks about he endurance bioenergy reactor—a device that contains bacteria that can convert energy from the sun into fuel molecules.

  7. Preliminary Multiphysics Analyses of HFIR LEU Fuel Conversion using COMSOL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Freels, James D; Bodey, Isaac T; Arimilli, Rao V

    The research documented herein was performed by several individuals across multiple organizations. We have previously acknowledged our funding for the project, but another common thread among the authors of this document, and hence the research performed, is the analysis tool COMSOL. The research has been divided into categories to allow the COMSOL analysis to be performed independently to the extent possible. As will be seen herein, the research has progressed to the point where it is expected that next year (2011) a large fraction of the research will require collaboration of our efforts as we progress almost exclusively into three-dimensionalmore » (3D) analysis. To the extent possible, we have tried to segregate the development effort into two-dimensional (2D) analysis in order to arrive at techniques and methodology that can be extended to 3D models in a timely manner. The Research Reactors Division (RRD) of ORNL has contracted with the University of Tennessee, Knoxville (UTK) Mechanical, Aerospace and Biomedical Engineering Department (MABE) to perform a significant fraction of this research. This group has been chosen due to their expertise and long-term commitment in using COMSOL and also because the participating students are able to work onsite on a part-time basis due to the close proximity of UTK with the ORNL campus. The UTK research has been governed by a statement of work (SOW) which clearly defines the specific tasks reported herein on the perspective areas of research. Ph.D. student Isaac T. Bodey has focused on heat transfer, fluid flow, modeling, and meshing issues and has been aided by his major professor Dr. Rao V. Arimilli and is the primary contributor to Section 2 of this report. Ph.D student Franklin G. Curtis has been focusing exclusively on fluid-structure interaction (FSI) due to the mechanical forces acting on the plate caused by the flow and has also been aided by his major professor Dr. Kivanc Ekici and is the primary contributor to Section 4 of this report. The HFIR LEU conversion project has also obtained the services of Dr. Prashant K. Jain of the Reactor & Nuclear Systems Division (RNSD) of ORNL. Prashant has quickly adapted to the COMSOL tools and has been focusing on thermal-structure interaction (TSI) issues and development of alternative 3D model approaches that could yield faster-running solutions. Prashant is the primary contributor to Section 5 of the report. And finally, while incorporating findings from all members of the COMSOL team (i.e., the team) and contributing as the senior COMSOL leader and advocate, Dr. James D. Freels has focused on the 3D model development, cluster deployment, and has contributed primarily to Section 3 and overall integration of this report. The team has migrated to the current release of COMSOL at version 4.1 for all the work described in this report, except where stated otherwise. Just as in the performance of the research, each of the respective sections has been originally authored by the respective authors. Therefore, the reader will observe a contrast in writing style throughout this document.« less

  8. Nuclear Rocket Technology Conference

    NASA Technical Reports Server (NTRS)

    1966-01-01

    The Lewis Research Center has a strong interest in nuclear rocket propulsion and provides active support of the graphite reactor program in such nonnuclear areas as cryogenics, two-phase flow, propellant heating, fluid systems, heat transfer, nozzle cooling, nozzle design, pumps, turbines, and startup and control problems. A parallel effort has also been expended to evaluate the engineering feasibility of a nuclear rocket reactor using tungsten-matrix fuel elements and water as the moderator. Both of these efforts have resulted in significant contributions to nuclear rocket technology. Many successful static firings of nuclear rockets have been made with graphite-core reactors. Sufficient information has also been accumulated to permit a reasonable Judgment as to the feasibility of the tungsten water-moderated reactor concept. We therefore consider that this technoIogy conference on the nuclear rocket work that has been sponsored by the Lewis Research Center is timely. The conference has been prepared by NASA personnel, but the information presented includes substantial contributions from both NASA and AEC contractors. The conference excludes from consideration the many possible mission requirements for nuclear rockets. Also excluded is the direct comparison of nuclear rocket types with each other or with other modes of propulsion. The graphite reactor support work presented on the first day of the conference was partly inspired through a close cooperative effort between the Cleveland extension of the Space Nuclear Propulsion Office (headed by Robert W. Schroeder) and the Lewis Research Center. Much of this effort was supervised by Mr. John C. Sanders, chairman for the first day of the conference, and by Mr. Hugh M. Henneberry. The tungsten water-moderated reactor concept was initiated at Lewis by Mr. Frank E. Rom and his coworkers. The supervision of the recent engineering studies has been shared by Mr. Samuel J. Kaufman, chairman for the second day of the conference, and Mr. Roy V. Humble. Dr. John C. Eward served as general chairman for the conference.

  9. ITER Status and Plans

    NASA Astrophysics Data System (ADS)

    Greenfield, Charles M.

    2017-10-01

    The US Burning Plasma Organization is pleased to welcome Dr. Bernard Bigot, who will give an update on progress in the ITER Project. Dr. Bigot took over as Director General of the ITER Organization in early 2015 following a distinguished career that included serving as Chairman and CEO of the French Alternative Energies and Atomic Energy Commission and as High Commissioner for ITER in France. During his tenure at ITER the project has moved into high gear, with rapid progress evident on the construction site and preparation of a staged schedule and a research plan leading from where we are today through all the way to full DT operation. In an unprecedented international effort, seven partners ``China, the European Union, India, Japan, Korea, Russia and the United States'' have pooled their financial and scientific resources to build the biggest fusion reactor in history. ITER will open the way to the next step: a demonstration fusion power plant. All DPP attendees are welcome to attend this ITER town meeting.

  10. Analog to digital converter system for temperature monitoring -- B, C, D, DR, F, and H reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ballowe, J.W.

    1961-03-23

    This document discusses a proposal that certain presently installed reactor process water outlet temperature data logging equipment in subject reactors to be replaced with new functionally simplified equipment of a more adequate design. The primary purpose of the proposed installation is to replace existing equipment which is obsolete and in three reactors is worn out to the point where the equipment is out of service frequently for periods of time up to 8 hours or more. The new equipment will provide reliable process tube temperature information for use in the functions of reactor control and product accountability. Based upon anticipatedmore » incremental production gains resulting from use of the new equipment, the amortization period for the project is calculated at 2.7 years.« less

  11. Axisymmetric MHD-stable Mirror as a Neutron Source and a Fusion Reactor

    ScienceCinema

    Dr. Dmitri Ryutov

    2018-04-17

    Dr. Ryutov discusses the concept of axisymmetric mirrors and presents an overview of current experiments and theories. Particular attention is paid to MHD stabilization and the advantages and disadvantages of using mirrors. Future work is identified and further discussed.

  12. Epitaxial Garnet Investigation; Technical Report, Foreign Travel

    DTIC Science & Technology

    1988-10-25

    Pure yttrium iron garnet (YIG) films are grown on GGG substrates by * liquid phase epitaxy ( LPE ) in production lots. In addition, one or two...epitaxial garnet films for Philips Dr. Krumme * Dr. Doormann 3-6-87 Thomson - CSF Research Center, Orsay, France Dr. J. P. Castera Dr. P. L. Meunier all...research physicists who grow, characterize, Dr. J. Y. Beguin or use epitaxial garnet films for Thomson CSF. Dr. J. L. Rolland Dr. P. Friez The

  13. Systems 2020

    DTIC Science & Technology

    2012-03-22

    USC Team Members: SERC Research Council Dr. Abhi Deshmukh , Purdue Dr. Michael Griffin. U. Alabama-Huntsville Dr. Barry Horowitz, U. Virginia Dr...Areas ................................................. 34 3.2.1 Affordability, Agility, and Resilience (Barry Boehm and Abhi Deshmukh , Leads...statement was reinterpreted to involve the SERC Research Council (Drs. Deshmukh , Griffin, Horowitz, Rouse, and Wade, with Dr. Boehm as chair) in defining

  14. Phalanx. Volume 47, Number 1

    DTIC Science & Technology

    2014-03-01

    for OR Analysts Dr. Jim Morris Overview of Academic Research Opportunities for OR Analysts Dr. Daniel Behringer September 21, 2012 Prize Winners...In Operations Research: Experiences and Perspectives Dr. Jim Morris and Major Brady Vaira (USAF) November 30, 2012 How Does Industry Use OR to...X X Ms. Lynda Liptak Applied Research Associates Publishing With MORS X X X X X Dr. Jim Morris US Air Force Operations Research in

  15. A Community College President--What's That? Forum 45.

    ERIC Educational Resources Information Center

    Cosand, Joseph P.; And Others

    This document compiles the Forum 45 major address and the responses of three reactors. Dr. Cosand's paper seeks to define what constitutes a top quality community college president. There are many styles of presidential leadership; however, the possibility of a president's providing strong and enlightened leadership depends on his effectiveness in…

  16. Wernher von Braun

    NASA Image and Video Library

    1966-06-21

    Dr. Joseph Randall, a laser expert at Marshall Space Flight Center (MSFC), explains one of the projects he is working on to a group composed of Federal Republic of Germany and MSFC officials. From left are: Dr. Randall; Minister for Scientific Research of Federal Republic of Germany, Dr. Gerhard Stolenberg; Director of MSFC Astrionics Lab, Dr. Walter Haeusserman; Head of Space Research Federal Republic of Germany, Max Mayer; MSFC Director Dr. von Braun; MSFC Deputy Director Dr. Elberhard Rees.

  17. SIAM Data Mining Brings It’ to Annual Meeting

    DTIC Science & Technology

    2017-02-24

    address space) languages. Jose Moreira and Manoj Kumar from IBM presented the Graph Programming Interface (GPI) as well as a proposal for a common...Samsi (MIT), Dr. Manoj Kumar (IBM Research), Dr. Michel Kinsy (Boston University), and Dr. Shashank Yellapantula (GE Global Research). Dr. Gadepally...and Dr. Samsi discussed advances in data management technologies [22–25], and Dr. Kumar presented a brief overview of a graph-based API IBM is

  18. Genomics, molecular imaging, bioinformatics, and bio-nano-info integration are synergistic components of translational medicine and personalized healthcare research.

    PubMed

    Yang, Jack Y; Yang, Mary Qu; Arabnia, Hamid R; Deng, Youping

    2008-09-16

    Supported by National Science Foundation (NSF), International Society of Intelligent Biological Medicine (ISIBM), International Journal of Computational Biology and Drug Design and International Journal of Functional Informatics and Personalized Medicine, IEEE 7th Bioinformatics and Bioengineering attracted more than 600 papers and 500 researchers and medical doctors. It was the only synergistic inter/multidisciplinary IEEE conference with 24 Keynote Lectures, 7 Tutorials, 5 Cutting-Edge Research Workshops and 32 Scientific Sessions including 11 Special Research Interest Sessions that were designed dynamically at Harvard in response to the current research trends and advances. The committee was very grateful for the IEEE Plenary Keynote Lectures given by: Dr. A. Keith Dunker (Indiana), Dr. Jun Liu (Harvard), Dr. Brian Athey (Michigan), Dr. Mark Borodovsky (Georgia Tech and President of ISIBM), Dr. Hamid Arabnia (Georgia and Vice-President of ISIBM), Dr. Ruzena Bajcsy (Berkeley and Member of United States National Academy of Engineering and Member of United States Institute of Medicine of the National Academies), Dr. Mary Yang (United States National Institutes of Health and Oak Ridge, DOE), Dr. Chih-Ming Ho (UCLA and Member of United States National Academy of Engineering and Academician of Academia Sinica), Dr. Andy Baxevanis (United States National Institutes of Health), Dr. Arif Ghafoor (Purdue), Dr. John Quackenbush (Harvard), Dr. Eric Jakobsson (UIUC), Dr. Vladimir Uversky (Indiana), Dr. Laura Elnitski (United States National Institutes of Health) and other world-class scientific leaders. The Harvard meeting was a large academic event 100% full-sponsored by IEEE financially and academically. After a rigorous peer-review process, the committee selected 27 high-quality research papers from 600 submissions. The committee is grateful for contributions from keynote speakers Dr. Russ Altman (IEEE BIBM conference keynote lecturer on combining simulation and machine learning to recognize function in 4D), Dr. Mary Qu Yang (IEEE BIBM workshop keynote lecturer on new initiatives of detecting microscopic disease using machine learning and molecular biology, http://ieeexplore.ieee.org/servlet/opac?punumber=4425386) and Dr. Jack Y. Yang (IEEE BIBM workshop keynote lecturer on data mining and knowledge discovery in translational medicine) from the first IEEE Computer Society BioInformatics and BioMedicine (IEEE BIBM) international conference and workshops, November 2-4, 2007, Silicon Valley, California, USA.

  19. Genomics, molecular imaging, bioinformatics, and bio-nano-info integration are synergistic components of translational medicine and personalized healthcare research

    PubMed Central

    2008-01-01

    Supported by National Science Foundation (NSF), International Society of Intelligent Biological Medicine (ISIBM), International Journal of Computational Biology and Drug Design and International Journal of Functional Informatics and Personalized Medicine, IEEE 7th Bioinformatics and Bioengineering attracted more than 600 papers and 500 researchers and medical doctors. It was the only synergistic inter/multidisciplinary IEEE conference with 24 Keynote Lectures, 7 Tutorials, 5 Cutting-Edge Research Workshops and 32 Scientific Sessions including 11 Special Research Interest Sessions that were designed dynamically at Harvard in response to the current research trends and advances. The committee was very grateful for the IEEE Plenary Keynote Lectures given by: Dr. A. Keith Dunker (Indiana), Dr. Jun Liu (Harvard), Dr. Brian Athey (Michigan), Dr. Mark Borodovsky (Georgia Tech and President of ISIBM), Dr. Hamid Arabnia (Georgia and Vice-President of ISIBM), Dr. Ruzena Bajcsy (Berkeley and Member of United States National Academy of Engineering and Member of United States Institute of Medicine of the National Academies), Dr. Mary Yang (United States National Institutes of Health and Oak Ridge, DOE), Dr. Chih-Ming Ho (UCLA and Member of United States National Academy of Engineering and Academician of Academia Sinica), Dr. Andy Baxevanis (United States National Institutes of Health), Dr. Arif Ghafoor (Purdue), Dr. John Quackenbush (Harvard), Dr. Eric Jakobsson (UIUC), Dr. Vladimir Uversky (Indiana), Dr. Laura Elnitski (United States National Institutes of Health) and other world-class scientific leaders. The Harvard meeting was a large academic event 100% full-sponsored by IEEE financially and academically. After a rigorous peer-review process, the committee selected 27 high-quality research papers from 600 submissions. The committee is grateful for contributions from keynote speakers Dr. Russ Altman (IEEE BIBM conference keynote lecturer on combining simulation and machine learning to recognize function in 4D), Dr. Mary Qu Yang (IEEE BIBM workshop keynote lecturer on new initiatives of detecting microscopic disease using machine learning and molecular biology, http://ieeexplore.ieee.org/servlet/opac?punumber=4425386) and Dr. Jack Y. Yang (IEEE BIBM workshop keynote lecturer on data mining and knowledge discovery in translational medicine) from the first IEEE Computer Society BioInformatics and BioMedicine (IEEE BIBM) international conference and workshops, November 2-4, 2007, Silicon Valley, California, USA. PMID:18831773

  20. Understanding anthocyanin: Researcher and educator Dr. Ron Wrolstad

    USDA-ARS?s Scientific Manuscript database

    This invited presentation is in honor of Dr. Ronald E. Wrolstad (Distinguished Professor Emeritus), recipient of the 2017 ACS AGFD Advancement of the Application of Agricultural and Food Chemistry Award. The talk will be a brief overview of Dr. Ronald E. Wrolstad’s research program and career; Dr. W...

  1. Canadian Rheumatology Association Meeting, The Westin Ottawa, Ottawa, Ontario, Canada, February 8-11, 2017.

    PubMed

    Silverman, Earl D

    2017-05-01

    The 72nd Annual Meeting of The Canadian Rheumatology Association (CRA) was held at The Westin Ottawa, Ottawa, Ontario, Canada, February 8-11, 2017. The program consisted of presentations covering original research, symposia, awards, and lectures. Highlights of the meeting include the following 2017 award winners: Dr. Vinod Chandran, Young Investigator; Dr. Jacques P. Brown, Distinguished Investigator; Dr. David Robinson, Teacher-Educator; Dr. Michel Zummer, Distinguished Rheumatologist; Ms. Rebecca Gole, Best Abstract on SLE Research by a Trainee - Ian Watson Award; Ms. Bailey Russell, Best Abstract on Clinical or Epidemiology Research by a Trainee - Phil Rosen Award; Dr. Sahil Koppikar and Dr. Henry Averns, Practice Reflection Award; Dr. Shirine Usmani, Best Abstract on Basic Science Research by a Trainee; Ms. Carol Dou, Best Abstract for Research by an Undergraduate Student; Dr. Dania Basodan, Best Abstract on Research by a Rheumatology Resident; Dr. Claire Barber, Best Abstract on Adult Research by Young Faculty; Ms. Audrea Chen, Best Abstract by a Medical Student; Dr. Kun Huang, Best Abstract by a Post-Graduate Resident; and Dr. Ryan Lewinson, Best Abstract by a Post-Graduate Research Trainee. Lectures and other events included a Keynote Lecture by Jonathon Fowles: Exercise is Medicine: Is Exercise a Good or Bad Thing for People with Arthritis?; State of the Art Lecture by Matthew Warman: Insights into Bone Biology and Therapeutics Gleaned from the Sustained Investigation of Rare Diseases; Dunlop-Dottridge Lecture by Allen Steere: Lyme Disease: A New Problem for Rheumatologists in Canada; and the Great Debate: Be it Resolved that the Least Expensive Treatment Should be Chosen. Switch, Switch, Switch! Arguing for: Jonathan Chan and Antonio Avina, and against: Marinka Twilt and Glen Hazlewood. Topics such as rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, Sjögren syndrome, psoriatic arthritis, spondyloarthritis, vasculitis, osteoarthritis, fibromyalgia, pediatric rheumatology, and their respective diagnoses, treatments, and outcomes are reflected in the abstracts, which we are pleased to publish in this issue of The Journal .

  2. Index of Oral Histories Relating to Naval Research and Development

    DTIC Science & Technology

    1985-01-01

    Repositories: NWC, DTNSRDC, NHC Individuals mentioned: Amlie, Dr. Thomas S. LaBerge , Dr. Walter McLean, Dr. William B. Parsons, RADM William S. Smith...future of R&D in the Navy. Repositories: NWC, DTNSRDC, NHC Individuals mentioned: Bennett, Dr. Ira Hollingsworth, Dr. Guilford L. LaBerge , Dr. Walter...DTNSRDC, NHC Individuals mentioned: Hunter, Dr. Hugh LaBerge . Dr. Walter McLean, Dr. William B. Brode, Dr. Wallace C. Sage, Dr. Bruce Wilson, Dr. Haskell

  3. 2K09 and thereafter : the coming era of integrative bioinformatics, systems biology and intelligent computing for functional genomics and personalized medicine research.

    PubMed

    Yang, Jack Y; Niemierko, Andrzej; Bajcsy, Ruzena; Xu, Dong; Athey, Brian D; Zhang, Aidong; Ersoy, Okan K; Li, Guo-Zheng; Borodovsky, Mark; Zhang, Joe C; Arabnia, Hamid R; Deng, Youping; Dunker, A Keith; Liu, Yunlong; Ghafoor, Arif

    2010-12-01

    Significant interest exists in establishing synergistic research in bioinformatics, systems biology and intelligent computing. Supported by the United States National Science Foundation (NSF), International Society of Intelligent Biological Medicine (http://www.ISIBM.org), International Journal of Computational Biology and Drug Design (IJCBDD) and International Journal of Functional Informatics and Personalized Medicine, the ISIBM International Joint Conferences on Bioinformatics, Systems Biology and Intelligent Computing (ISIBM IJCBS 2009) attracted more than 300 papers and 400 researchers and medical doctors world-wide. It was the only inter/multidisciplinary conference aimed to promote synergistic research and education in bioinformatics, systems biology and intelligent computing. The conference committee was very grateful for the valuable advice and suggestions from honorary chairs, steering committee members and scientific leaders including Dr. Michael S. Waterman (USC, Member of United States National Academy of Sciences), Dr. Chih-Ming Ho (UCLA, Member of United States National Academy of Engineering and Academician of Academia Sinica), Dr. Wing H. Wong (Stanford, Member of United States National Academy of Sciences), Dr. Ruzena Bajcsy (UC Berkeley, Member of United States National Academy of Engineering and Member of United States Institute of Medicine of the National Academies), Dr. Mary Qu Yang (United States National Institutes of Health and Oak Ridge, DOE), Dr. Andrzej Niemierko (Harvard), Dr. A. Keith Dunker (Indiana), Dr. Brian D. Athey (Michigan), Dr. Weida Tong (FDA, United States Department of Health and Human Services), Dr. Cathy H. Wu (Georgetown), Dr. Dong Xu (Missouri), Drs. Arif Ghafoor and Okan K Ersoy (Purdue), Dr. Mark Borodovsky (Georgia Tech, President of ISIBM), Dr. Hamid R. Arabnia (UGA, Vice-President of ISIBM), and other scientific leaders. The committee presented the 2009 ISIBM Outstanding Achievement Awards to Dr. Joydeep Ghosh (UT Austin), Dr. Aidong Zhang (Buffalo) and Dr. Zhi-Hua Zhou (Nanjing) for their significant contributions to the field of intelligent biological medicine.

  4. 2K09 and thereafter : the coming era of integrative bioinformatics, systems biology and intelligent computing for functional genomics and personalized medicine research

    PubMed Central

    2010-01-01

    Significant interest exists in establishing synergistic research in bioinformatics, systems biology and intelligent computing. Supported by the United States National Science Foundation (NSF), International Society of Intelligent Biological Medicine (http://www.ISIBM.org), International Journal of Computational Biology and Drug Design (IJCBDD) and International Journal of Functional Informatics and Personalized Medicine, the ISIBM International Joint Conferences on Bioinformatics, Systems Biology and Intelligent Computing (ISIBM IJCBS 2009) attracted more than 300 papers and 400 researchers and medical doctors world-wide. It was the only inter/multidisciplinary conference aimed to promote synergistic research and education in bioinformatics, systems biology and intelligent computing. The conference committee was very grateful for the valuable advice and suggestions from honorary chairs, steering committee members and scientific leaders including Dr. Michael S. Waterman (USC, Member of United States National Academy of Sciences), Dr. Chih-Ming Ho (UCLA, Member of United States National Academy of Engineering and Academician of Academia Sinica), Dr. Wing H. Wong (Stanford, Member of United States National Academy of Sciences), Dr. Ruzena Bajcsy (UC Berkeley, Member of United States National Academy of Engineering and Member of United States Institute of Medicine of the National Academies), Dr. Mary Qu Yang (United States National Institutes of Health and Oak Ridge, DOE), Dr. Andrzej Niemierko (Harvard), Dr. A. Keith Dunker (Indiana), Dr. Brian D. Athey (Michigan), Dr. Weida Tong (FDA, United States Department of Health and Human Services), Dr. Cathy H. Wu (Georgetown), Dr. Dong Xu (Missouri), Drs. Arif Ghafoor and Okan K Ersoy (Purdue), Dr. Mark Borodovsky (Georgia Tech, President of ISIBM), Dr. Hamid R. Arabnia (UGA, Vice-President of ISIBM), and other scientific leaders. The committee presented the 2009 ISIBM Outstanding Achievement Awards to Dr. Joydeep Ghosh (UT Austin), Dr. Aidong Zhang (Buffalo) and Dr. Zhi-Hua Zhou (Nanjing) for their significant contributions to the field of intelligent biological medicine. PMID:21143775

  5. Dr. Irene Sänger-Bredt, a life for astronautics

    NASA Astrophysics Data System (ADS)

    Zaganescu, Nicolae-Florin

    2004-12-01

    Irene Bredt (b.1911 at Bonn) obtained her Doctorate in Physics in 1937; in the same year she became a scientific researcher at the German Research Center for Aviation at Trauen, led by Prof. Dr. Eugen Sänger. Soon, the young but efficient Dr. Irene Bredt became the first assistant of Dr. Sänger, who married her (1951). During 1973-1978, Dr. Bredt was in correspondence with Prof. Dr. Nikolae-Florin Zaganescu and helped him to familiarize the Romanian readers with Prof. Sänger's life and achievements. As for Dr. Bredt's life, she specified three main periods of her activity: 1937-1942, when she was researcher in charge of thermodynamic problems of liquid-fuelled rocket engines at Trauen 1942-1945, when she was Senior Researcher in charge of Ramjet in flight performances at Ainring, and also coauthored the Top Secret Technical report entitled 'A Rocket Engine for a Long-Range Bomber', which was finished in 1941 but edited only in 1944 the post world war II period, when she was Scientific Advisor or Director at various civil and military research institutes, universities, etc. Dr. Irene Sänger-Bredt helped her husband to develop many scientific theories like Ramjet thermodynamic theory, and photon rocket theory and also in establishing IAF and IAA. In 1970, Dr. Irene Sänger-Bredt was honored with 'Hermann Oberth Gold Medal' for her impressive scientific activity.

  6. Antenna Development for Multifunctional Armor Applications Using Embedded Spin-Torque Nano-Oscillator (STNO) as a Microwave Detector

    DTIC Science & Technology

    2011-08-09

    Elena Bankowski (Research Engineer) & Mr. Steven Zielinski (Engineer). •Oakland University Research Team: Dr. Andrei Slavin (Chair, Physics...Dr. Grace Bochenek, the Chief Scientist Dr. Dave Gorsich and GVSS Associate Director Mr. Steve Knott for their support of this innovative research

  7. Nanoscience and Technology at the Air Force Research Laboratory (AFRL)

    DTIC Science & Technology

    2005-05-01

    AIR FORCE RESEARCH LABORATORY ( AFRL ) Dr. Richard A. Vaia Dr. Daniel Miracle Dr. Thomas Cruse Air Force Research ...Technology At The Air Force Research Laboratory ( AFRL ) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...98) Prescribed by ANSI Std Z39-18 AFRL NST Overview 2 AIR FORCE RESEARCH LABORATORY VISION We defend

  8. Nanoscience and Technology at the Air Force Research Laboratory (AFRL)

    DTIC Science & Technology

    2005-02-01

    AIR FORCE RESEARCH LABORATORY ( AFRL ) Dr. Richard A. Vaia Dr. Daniel Miracle Dr. Thomas Cruse Air Force Research ...Technology At The Air Force Research Laboratory ( AFRL ) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...98) Prescribed by ANSI Std Z39-18 AFRL NST Overview 2 AIR FORCE RESEARCH LABORATORY VISION We defend

  9. Identifying the Experimental and Theoretical Effective Characteristics of Nonaligned Anisotropic Metamaterials

    DTIC Science & Technology

    2015-06-18

    nanorods, while the second demonstrated long and skinny nanorods. This is demosntrated in Figure 20. The University of Dayton research group asked Dr...here and in other research carried out with this methodology. 5.4 Simulations 5.4.1 Experimental results. All of the simulations carried out in this...samples that Dr. Sarangan and Dr. Shah of the University of Dayton presented to Dr. Marciniak’s research group . The samples consisted of silver tilted

  10. 75 FR 47646 - Idaho State University; Notice of Issuance of Director's Decision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ... detector from the reactor core. In the petition Dr. Crawford states that this was cited as an Apparent... detector. The personnel roof access hatch was also addressed in Rev. 3 and Rev. 4 of the Physical Security... procedures to wear protective clothing to routinely remove the activated startup channel detector from the...

  11. US Air Force 1989 Research Initiation Program. Volume 4.

    DTIC Science & Technology

    1992-06-25

    Kentucky University Specialty: Mechanical Engineering Svecialty: Analytical Chemistry 760-7MG-079 and 210-IOMG-095 Dr. Thomas Lalk Texas A&M University...Base) Dr. Peter Armendarez Mr. William Newbold (GSRP) Brescia College University of Florida Secialty: Physical Chemistry Specialty: Aerospace...Research Dr. Roger Bunting Dr. Steven Trogdon Illinois State University University of Minnesota-Duluth Specialty: Inorganic Chemistry Specialty

  12. Additional Analysis of the ESTCP Discrimination Study Data at Camp Sibert, Alabama. Project 200504: Practical Discrimination Strategies for Application to Live Sites

    DTIC Science & Technology

    2008-10-20

    Dr. Stephen Billings Dr. Leonard Pasion Sky Research, Inc) Laurens Beran UBC-GIF Approved for public release; distribution...Sites 5. FUNDING NUMBERS Contract # W912HQ-05-C-0018 6. AUTHOR(S) Dr. Stephen Billings, Dr. Leonard Pasion (Sky Research, Inc.) Laurens Beran...representative of the test datasets. ESTCP MM-0504: Additional Analysis of Camp Sibert Data Sky Research Inc October 2008 References [1] L.R. Pasion , N

  13. Second Order Non-Linear Optical Polyphosphazenes. Proceedings of Symposium on Non-Linear Optics, ACS Meeting, Held in Boston, Massachusetts 1990

    DTIC Science & Technology

    1990-03-23

    Paciorek Dr. William B. Moniz Ultrasystems Defense and Space, Inc. Code 6120 16775 Von Karman Avenue Naval Research Laboratory Irvine, CA 92714 Washington...413h004 Dr. Les H. Sperling Dr. Richard S. Stein Materials Research Center #32 Polymer Research Institute Lehigh University University of Massachusetts

  14. Dr. Ted Trimble: Why I Do Cancer Research

    Cancer.gov

    In a video, Dr. Ted Trimble talks about the importance of cancer research. World Cancer Research Day commemorates the important role research and cancer researchers play in reducing the global burden of cancer.

  15. Recent results on the neutron irradiation of ITER candidate copper alloys irradiated in DR-3 at 250{degrees}C to 0.3 dpa

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Edwards, D.J.; Singh, B.N.; Toft, P.

    1997-04-01

    Tensile specimens of CuCrZr and CuNiBe alloys were given various heat treatments corresponding to solution anneal, prime-ageing and bonding thermal treatment with additional specimens re-aged and given a reactor bakeout treatment at 350{degrees}C for 100 h. CuAl-25 was also heat treated to simulate the effects of a bonding thermal cycle on the material. A number of heat treated specimens were neutron irradiated at 250{degrees}C to a dose level of {approximately}0.3 dpa in the DR-3 reactor as Riso. The main effect of the bonding thermal cycle heat treatment was a slight decrease in strength of CuCrZr and CuNiBe alloys. The strengthmore » of CuAl-25, on the other hand, remained almost unaltered. The post irradiation tests at 250{degrees}C showed a severe loss of ductility in the case of the CuNiBe alloy. The irradiated CuAl-25 and CuCrZr specimens exhibited a reasonable amount of uniform elongation, with CuCrZr possessing a lower strength.« less

  16. 50th Anniversary Celebration: 46th Sagamore Army Materials Research Conference on Advances and Needs in Multi-Spectral Transparent Materials Technology

    DTIC Science & Technology

    2008-09-01

    68 (4), 883–887. Li, C-W.; Yamanishi, J. Ceram. Eng. Sci. Proc. 1989, 10, 632–645. Li, J.-G.; Ikegami , T .; Lee, J.-H.; Mori, T .; J. Am. Ceram. Soc...and Opening Remarks Dr. Allen Grum Associate Director for Science and Technology (S& T ), ARL The Impact of Research on Soldier Protection Ms. Jill...Crystal Systems, Dr. Chandra Khattak 3. MSI, Dr. Les Bowen 4. TA& T , Dr. Larry Fehrenbacher 5. CeraNova, Dr. Marina Pascucci Session IV

  17. ARC-2010-ACD10-0066-001

    NASA Image and Video Library

    2010-04-09

    Netherlands Memorandum of Record (MOR) agreement signing and visit to the NASA Ames Research Center, Mofffett Field, California. At the table are left to right, Dr. Scott Sanford, NASA Ames, Dr Alexander Tielens, former NASA Civil Servant and former SOFIA Project Scientist, Dr Andrew Mattioda, NASA Ames, Dr. Louis B.J.Vertegaal, Director of Physical Sciences, Chemistry, and Advanced Chemical Technologies for Sustainability, of the Netherlands Organisation for Scientific Research (NWO)

  18. The research contributions of Dr. Paul Van Deusen

    Treesearch

    Thomas B. Lynch; Francis A. Roesch; John Paul McTague; Jeffrey H. Gove; Gregory A. Reams; Aaron R. Weiskittel

    2015-01-01

    Dr. Paul Van Deusen’s recent passing concluded a rich 30+-year research career dedicated to development and implementation of quantitative methods for forestry and natural resources. Since the early part of his career as a biometrician with the USDA Forest Service Southern Research Station in the 1980s-1990s and continuing with his later employment at NCASI, Dr. Van...

  19. A Solvable Self-Similar Model of the Sausage Instability in a Resistive Z-Pinch

    DTIC Science & Technology

    1989-09-20

    Ithaca, NY 14853 Dr. V. Nardi Dr. John C. Riordan Stevens Institute of Technology Physics International Co. Hoboken, NJ 07803 2700 Merced Street Dr...92122 Dr. Rick B. Spielman Dr. Frank C. Young Sandia National Laboratories Naval Research Laboratory P.O. Box 5800 Code 4770.1 Albuquerque, NM 87115

  20. Feature Extraction and Classification of Magnetic and EMI Data, San Luis Obispo, CA

    DTIC Science & Technology

    2010-07-01

    Stephen Billings Dr. Len Pasion Dr. Nicolas Lhomme Kevin Kingdon Jon Jacobson Sky Research, Inc. Dr. Douglas Oldenburg Dr. Lin Ping Song...Discrimination Strategies for Application to Live Sites W912HQ-05-C-0018 ESTCP 0504Dr. Stephen Billings, Dr. Len Pasion , Dr. Nicolas Lhomme, Kevin...e.g. Hart et al., 2001; Collins et al., 2001; Pasion & Oldenburg, 2001; Zhang et al., 2003a, 2003b; Billings, 2004). The most promising discrimination

  1. Solid Propellant Combustion Mechanism Research 1975-1980.

    DTIC Science & Technology

    1980-04-01

    Roberto Office of Naval Research 1 AFSC Western Office Andrews AFB, Code DLFP 1030 East Green Street Washington, DC 20334 Pasadena, CA 91106 Attn: Mr...Office Atmospheric Sciences 495 Summer Street Bolling Air Force Base Boston, MA 02210 Washington, DC 20332 Attn: Dr. L. Peebles Dr. A. Wood Air Force... Bolling Air Force Base San Francisco, CA 94102 Washington, DC 20332 Attn: Dr. P. A. Miller Attn: Dr. L. H. Caveny F Defense-Technical Information 12 Anal

  2. RDHWT/MARIAH II Hypersonic Wind Tunnel Research Program

    DTIC Science & Technology

    2008-09-01

    Diagnostics Dr. Gary Brown – Gas Dynamics Dr. Ihab Girgis – Modeling Dr. Dennis Mansfield – Experimental Ring Technical Services Dr. Leon Ring – Systems...wind tunnel (MSHWT) with Mach 8 to 15, true -temperature flight test capabilities. This research program was initiated in fiscal year (FY) 1998 and is...Force test capabilities that exist today. Performance goals of the MSHWT are true temperature, Mach 8 to 15, dynamic pressure of 500 to 2000 psf (24 to

  3. Texas Heart Institute

    MedlinePlus

    ... International Symposium on Stem Cell Therapy and Cardiovascular Innovations in Madrid this month. Dr. Martin and his ... lab’s researchers. THI's Director of Electrophysiology Clinical Research & Innovations Dr. Mehdi Razavi and researchers at Rice University ...

  4. 2011 Presidential Early Career Awards for Scientists and Engineers: the PECASE Awards Ceremony

    ScienceCinema

    Poneman, Daniel

    2018-05-31

    The winners for 2011 of the DOE PECASE Awards were recognized in a ceremony held August 01, 2012. Dr. Bill Brinkman, Director of the Office of Science introduced the main speaker, DOE Deputy Secretary Daniel B. Poneman. Leaders from across the Department and the fields of energy research and technology presented the 2011 winners. They are: Dr. Stanley Atcitty (SNL); Dr. Jeffrey W. Banks (LLNL); Dr. Amy J. Clarke (LANL); Derek R. Gaston (INL); Dr. Christopher Hirata (California Institute of Technology); Dr. Heileen Hsu-Kim (Duke University); Dr. Thomas Francisco (Jaramillo Stanford University); Dr.Pablo Jarillo-Herrero (MIT); Dr. Peter Mueller (ANL); Dr. Daniel B. Sinars (SNL); Dr. Jesse Thaler (MIT); and Dr. Heather Whitley (LLNL).

  5. 2011 Presidential Early Career Awards for Scientists and Engineers: the PECASE Awards Ceremony

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Poneman, Daniel

    2012-08-01

    The winners for 2011 of the DOE PECASE Awards were recognized in a ceremony held August 01, 2012. Dr. Bill Brinkman, Director of the Office of Science introduced the main speaker, DOE Deputy Secretary Daniel B. Poneman. Leaders from across the Department and the fields of energy research and technology presented the 2011 winners. They are: Dr. Stanley Atcitty (SNL); Dr. Jeffrey W. Banks (LLNL); Dr. Amy J. Clarke (LANL); Derek R. Gaston (INL); Dr. Christopher Hirata (California Institute of Technology); Dr. Heileen Hsu-Kim (Duke University); Dr. Thomas Francisco (Jaramillo Stanford University); Dr.Pablo Jarillo-Herrero (MIT); Dr. Peter Mueller (ANL); Dr.more » Daniel B. Sinars (SNL); Dr. Jesse Thaler (MIT); and Dr. Heather Whitley (LLNL).« less

  6. Technial Programme Committee

    NASA Astrophysics Data System (ADS)

    2014-06-01

    Chairpersons Dr Dinesh Sathyamoorthy, Science & Technology Research Institute for Defence (STRIDE), Ministry of Defence, Malaysia Associate Professor Sr Dr Abdul Rashid Mohamed Shariff, Universiti Putra Malaysia (UPM), Malaysia Dr Ahmad Fikri Abdullah, Universiti Putra Malaysia (UPM), Malaysia Dr Farrah Melissa Muharram, Universiti Putra Malaysia (UPM), Malaysia Members Professor Dr Li Jing, Beijing Normal University, China Professor Dr Iyyanki Muralikrishna, Administrative Staff College of India (ASCI), India Professor Dr Alias Abdul Rahman, Universiti Teknologi Malaysia (UTM), Malaysia Professor Dr Ismat Mohamed El Hassan, King Saud University, Saudi Arabia Professor Dr George Miliaresis, Open University of Cyprus, Cyprus Professor Dr Christine Pohl, Universiti Teknologi Malaysia (UTM), Malaysia Professor Dr Mahender Kotha, Goa University, India Associate Professor Dr Paolo Gamba, University of Pavia, Italy Associate Professor Dr Behara Seshadri Daya Sagar, Indian Statistical Institute (ISI), India Associate Professor Sr Ranjit Singh, Infrastructure University Kuala Lumpur (IUKL), Malaysia Associate Professor Dr Abdul Nasir Matori, Universiti Teknologi Petronas (UTP), Malaysia Associate Dr Lucian Dragut, West University of Timişoara, Romania Associate Professor Dr Saied Pirasteh, Islamic Azad University, Iran Associate Professor Dr Peter Yuen, Cranfield University, United Kingdom Associate Professor Dr Lim Hwee San, Universiti Sains Malaysia (USM), Malaysia Associate Professor Dr Wayan Suparta, Universiti Kebangsaan Malaysia (UKM), Malaysia Associate Professor Dr Tuong Thuy Vu, The University of Nottingham Malaysia Campus, Malaysia Associate Professor Dr Maged Mahmoud Marghany, Universiti Teknologi Malaysia (UTM), Malaysia Associate Professor Dr Rami Al-Ruzouq, University of Sharjah, UAE Associate Professor Dr Biswajeet Pradhan, Universiti Putra Malaysia (UPM), Malaysia Associate Professor Dr Helmi Zulhaidi Mohd Shafri, Universiti Putra Malaysia (UPM), Malaysia Associate Professor Dr Benny Peter, Universiti Teknologi Malaysia (UTM), Malaysia Associate Professor Dr Norzailawati Mohd Nor, International Islamic University Malaysia (IIUM), Malaysia Dr Josée Lévesque, Defence Research and Development Canada (DRDC), Canada Dr Ali Ariapour, Islamic Azad University, Iran Dr Zulkiflee Abd Latif, Universiti Teknologi MARA (UiTM), Malaysia Dr Lim Tien Sze, Multimedia University (MMU), Malaysia Dr Ruzinoor Che Mat, Universiti Utara Malaysia (UUM), Malaysia Dr Eran Sadek Said Md Sadek, Universiti Teknologi MARA (UiTM), Malaysia Dr Siti Khairunniza Bejo, Universiti Putra Malaysia (UPM) Dr Ramin Nourqolipour, National Organization of Forest, Range and Watershed Manage Sr Mohktar Azizi Mohd Din, Universiti Malaya Col (Rt) Frederic Hernoust, Magelli Marzieh Mokarram, University of Isf Mohd Fadhil Abuhan, Royal Malaysian Police, Malaysia

  7. Like Father, Like Doctor

    ERIC Educational Resources Information Center

    Henderson, Nancy

    2008-01-01

    In this article, the author profiles Dr. Jack Kessler, chair of the Department of Neurology at Northwestern University Feinberg School of Medicine. Dr. Jack Kessler is a renowned stem cell expert and researcher. For years, Dr. Kessler had been researching ways to repair damage to the nervous system. It was not until his own daughter became…

  8. Antenna Development for Multifunctional Armor Applications Using Embedded Spin-Torque Nano-Oscillator (STNO) as a Microwave Detector

    DTIC Science & Technology

    2011-08-01

    Thomas Meitzler (Team Leader, Research Engineer), Dr. Elena Bankowski (Research Engineer) & Mr. Steven Zielinski (Engineer). •Oakland University...our experiments. •We would like to thank TARDEC Director Dr. Grace Bochenek, the Chief Scientist Dr. Dave Gorsich and GVSS Associate Director Mr. Steve

  9. Extremophiles and Space Exploration

    NASA Technical Reports Server (NTRS)

    Paulino Lima, Ivan Glaucio

    2016-01-01

    In this presentation, Dr. Paulino Lima will give a brief introduction of the Universities Space Research Association, and an overview of Dr. Lynn Rothschild's research projects at NASA Ames with emphasis on his research projects.

  10. Approximating Multivariate Normal Orthant Probabilities Using the Clark Algorithm.

    DTIC Science & Technology

    1987-07-15

    Kent Eaton Army Research Institute Dr. Hans Crombag 5001 Eisenhower Avenue University of Leyden Alexandria, VA 22333 Education Research Center...Boerhaavelaan 2 Dr. John M. Eddins 2334 EN Leyden University of Illinois The NETHERLANDS 252 Engineering Research Laboratory Mr. Timothy Davey 103 South...Education and Training Ms. Kathleen Moreno Naval Air Station Navy Personnel R&D Center Pensacola, FL 32508 Code 62 San Diego, CA 92152-6800 Dr. Gary Marco

  11. Naval Health Research Center 1985 Annual Report

    DTIC Science & Technology

    1985-01-01

    research. While much of our earlier work addressed organizational issues within the shote -based health care delivery sytem, more recent efforts have focused...Laboratory, Groton, Connecticut, cn the Neurometric Program. Dr. Naitoh met with Dr. Charles Winget of NASA Amen Rasearch Center for a research consultation...lag in commercial aircrews. Collaborators on the project include LT COL R. Curtis Graeber from NASA -Ames, Dr. Hans-Martin Wegmann from the West German

  12. Scientometric Analysis and Mapping of Scientific Articles on Diabetic Retinopathy.

    PubMed

    Ramin, Shahrokh; Gharebaghi, Reza; Heidary, Fatemeh

    2015-01-01

    Diabetic retinopathy (DR) is the major cause of blindness among the working-age population globally. No systematic research has been previously performed to analyze the research published on DR, despite the need for it. This study aimed to analyze the scientific production on DR to draw overall roadmap of future research strategic planning in this field. A bibliometric method was used to obtain a view on the scientific production about DR by the data extracted from the Institute for Scientific Information (ISI). Articles about DR published in 1993-2013 were analyzed to obtain a view of the topic's structure, history, and to document relationships. The trends in the most influential publications and authors were analyzed. Most highly cited articles addressed epidemiologic and translational research topics in this field. During the past 3 years, there has been a trend toward biomarker discovery and more molecular translational research. Areas such as gene therapy and micro-RNAs are also among the recent hot topics. Through analyzing the characteristics of papers and the trends in scientific production, we performed the first scientometric report on DR. Most influential articles have addressed epidemiology and translational research subjects in this field, which reflects that globally, the earlier diagnosis and treatment of this devastating disease still has the highest global priority.

  13. Chesapeake Bay Study. Supplement A. Problem Identification. Supplement B. Public Involvement. Supplement C. The Chesapeake Bay Hydraulic Model.

    DTIC Science & Technology

    1984-09-01

    1968-71 Dr. Francis S. L. Williamson, 1971-75 Dr. J. Kevin Sullivan, 1975-83 Dr. David L. Correll, 1983-84 B-I...BASIC RESEARCH (cont’d) SMITHSONIAN INSTITUTION Dr. I. Eugene Wallen, 1968-71 Dr. Francis S. L. Williamson, 1971-75 Dr. 3. Kevin Sullivan, 1975-83 Dr...MSX merical fishino and recrea- by increased distributions of waer sources fromsaltitru- the B E P predicted oysters tion industries and for the

  14. DNA Double-strand Breaks Induced byFractionated Neutron Beam Irradiation for Boron Neutron Capture Therapy.

    PubMed

    Kinashi, Yuko; Yokomizo, Natsuya; Takahashi, Sentaro

    2017-04-01

    To use the 53BP1 foci assay to detect DNA double-strand breaks induced by fractionated neutron beam irradiation of normal cells. The Kyoto University Research Reactor heavy-water facility and gamma-ray irradiation system were used as experimental radiation sources. After fixation of Chinese Hamster Ovary cells with 3.6% formalin, immunofluorescence staining was performed. Number and size of foci were analyzed using ImageJ software. Fractionated neutron irradiation induced 25% fewer 53BP1 foci than single irradiation at the same dose. By contrast, gamma irradiation induced 30% fewer 53BP1 foci than single irradiation at the same dose. Fractionated neutron irradiation induced larger foci than gamma irradiation, raising the possibility that persistent unrepaired DNA damage was amplified due to the high linear energy transfer component in the neutron beam. Unrepaired cluster DNA damage was more prevalent after fractionated neutron irradiation than after gamma irradiation. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  15. Trends in Retinal Damage Thresholds from 100-Millisecond Near-Infrared Laser Radiation Exposures: A Study at 1,110, 1,130, 1,150, and 1,319 nm

    DTIC Science & Technology

    2009-01-01

    Ste B-100 Directed Energy Bioeffects Division San Antonio, TX 78228 Optical Radiation Branch 2624 Louis Bauer Dr. Brooks City-Base, TX...S) Air Force Research Laboratory Human Effectiveness Directorate Directed Energy Bioeffects Division Optical Radiation Branch 2624 Louis Bauer Dr...Research Laboratory, 711th HPW, Optical Radiation Branch, 2624 Louis Bauer Dr., Brooks City-Base, Texas 78231 3Northrop Grumman, 4241 Woodcock Dr. Ste. B

  16. The American Journal of Cardiology and Journal of Periodontology editors' consensus: periodontitis and atherosclerotic cardiovascular disease.

    PubMed

    Friedewald, Vincent E; Kornman, Kenneth S; Beck, James D; Genco, Robert; Goldfine, Allison; Libby, Peter; Offenbacher, Steven; Ridker, Paul M; Van Dyke, Thomas E; Roberts, William C

    2009-07-01

    This Editors' Consensus is supported by an educational grant from Colgate-Palmolive, Inc., New York, New York, and is based on a meeting of the authors held in Boston, Massachusetts, on January 9, 2009. Dr. Friedewald has received honoraria for speaking from Novartis, East Hanover, New Jersey. Dr. Kornman is a full-time employee and shareholder of Interleukin Genetics, Waltham, Massachusetts, which owns patents on genetic biomarkers for chronic inflammatory diseases. Dr. Genco is a consultant to Merck, Whitehouse Station, New Jersey. Dr. Ridker has received research support from AstraZeneca, Wilmington, Delaware; Novartis; Pfizer, New York, New York; Roche, Nutley, New Jersey; Sanofi-Aventis, Bridgewater, New Jersey; and Abbott Laboratories, Abbott Park, Illinois. Dr. Ridker has received non-financial research support from Amgen, Thousand Oaks, California. Dr. Ridker is a co-inventor on patents held by Brigham and Women's Hospital that relate to the use of inflammatory biomarkers in cardiovascular disease. Dr. Ridker is a research consultant for Schering-Plough, Kenilworth, New Jersey; Sanofi-Aventis; AstraZeneca; Isis, Carlsbad, California; Novartis; and Vascular Biogenics, Tel Aviv, Israel. Dr. Van Dyke is a co-inventor on patents held by Boston University, Boston, Massachusetts, that relate to inflammation control, including consulting fees. Dr. Roberts has received honoraria for speaking from Merck, Schering-Plough, AstraZeneca, and Novartis. All other individuals in a position to control content disclosed no relevant financial relationships.

  17. capr-contact us | Center for Cancer Research

    Cancer.gov

    CAPR Contacts: Dr. Shyam Sharan, Director; Dr. Zoe Weaver Ohler, Preclinical Team Leader; Dr. Serguei Kozlov, Technology Optimization Team Leader; Ken Miller, Project Manager; Chris Hester, Administrative Assistant

  18. Sesquinaries, Magnetics and Atmospheres: Studies of the Terrestrial Moons and Exoplanets

    DTIC Science & Technology

    2016-12-01

    support provided by Red Sky Research, LLC. Computational support was provided by the NASA Ames Mission Design Division (Code RD) for research...Systems Branch (Code SST), NASA Ames Research Center, provided supercomputer access and computational resources for the work in Chapter 5. I owe a...huge debt of gratitude to Dr. Pete Worden, Dr. Steve Zornetzer, Dr. Alan Weston ( NASA ), and Col. Carol Welsch, Lt. Col Joe Nance and Lt. Col Brian

  19. Summary of Symposium on Cloud Systems, Hurricanes and TRMM: Celebration of Dr. Joanne Simpson's Career, The First Fifty Years

    NASA Technical Reports Server (NTRS)

    Tao, W.-K.; Adler, R.; Braun, S.; Einaudi, F.; Ferrier, B.; Halverson, J.; Heymsfield, G.; Kummerow, C.; Negri, A.; Kakar, R.; hide

    2000-01-01

    A symposium celebrating the first 50 years of Dr. Joanne Simpson's career took place at the NASA/Goddard Space Flight Center from December 1 - 3, 1999. This symposium consisted of presentations that focused on: historical and personal points of view concerning Dr. Simpson's research career, her interactions with the American Meteorological Society, and her leadership in TRMM; scientific interactions with Dr. Simpson that influenced personal research; research related to observations and modeling of clouds, cloud systems and hurricanes; and research related to the Tropical Rainfall Measuring Mission (TRMM). There were a total of 36 presentations and 103 participants from the US, Japan and Australia. The specific presentations during the symposium are summarized in this paper.

  20. Annotated Bibliography of Dr Salmani Nodoushan's Research on Education and Language Teaching

    ERIC Educational Resources Information Center

    Etemadfar Kashani, Abbas Ali

    2016-01-01

    This is an annotated bibliography of the research conducted on education and language teaching and assessment by Dr. Mohammad Ali Salmani Nodoushan in the past 25 years. This bibliography is a precise picture of the current state of education and language teaching and assessment in Iran. Dr. Salmani Nodoushan is the most distinguished Iranian…

  1. Relative Ball 3X-VSR reactivity strength DR reactor. Interim Report of PT IP-126-C

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simpson, D.E.

    1959-06-01

    Prior to this experiment, no measurements of Ball 3X effectiveness had been performed for any of the older 2004-tube Hanford piles, and calculations concerning total control requirements were made assuming the vertical safety system strength equal to the strength of the B, D, F vertical safety rods. With current and projected enrichment loadings, the vertical control system was calculated to be inadequate to satisfy the total control criteria at all times, resulting in the necessity to provide supplementary control in the form of horizontal rods or temporary process tube poison. Because of the larger ball channels at DR, the Ballmore » 3X system is stronger than at the other 29-VSR piles. Therefore, the potential relaxation of total control limits was greater for DR should an experiment show the Ball 3X strength to be significantly greater than the B, D, F VSR strength. PT-IP-126-C authorized an experiment to determine the Ball 3X effectiveness at DR Pile by measurement of the relative strength of a VSR and a column of 3X balls in the same channel. The experiment was performed in March, 1958, and on the strength of favorable results a supplement to the PT was prepared to authorize the same test at one of the other 29-VSR piles. This supplement has not been approved; therefore, the results of the DR test are being reported separately in this document.« less

  2. Catalytic Oxidation of Vanillyl Alcohol Using FeMCM-41 Nanoporous Tubular Reactor

    NASA Astrophysics Data System (ADS)

    Elamathi, P.; Kolli, Murali Krishna; Chandrasekar, G.

    Iron containing nanoporous MCM-41 (FeMCM-41) with different Si/Fe ratios of 50, 100 and 150 was synthesized by hydrothermal synthesis process. The materials obtained from hydrothermal synthesis were characterized by various physico chemical techniques such as XRD, N2 adsorption, DR UV-vis, EPR and FTIR spectroscopy. XRD analyses of FeMCM-41 materials confirmed the presence of well-ordered crystalline structure. N2 isotherm of FeMCM-41 materials showed type IV adsorption isotherm. EPR and DR UV-vis analysis of FeMCM-41 samples indicates the presence of high tetrahedral coordination at the Si/Fe ratios of 100 and 150. The catalytic performance of FeMCM-41 nano tubular reactor was tested in the liquid phase oxidation of vanillyl alcohol into vanillin using H2O2 (50wt% in water). The reaction products were analyzed by gas chromatography in DB-5 capillary column with flame ionization detector. The products were confirmed by 1H NMR, 13C NMR and LC-Mass spectroscopy. The maximum conversion of vanillyl alcohol (85%) and selectivity towards vanillin (82%) were observed using the catalyst FeMCM-41(100) in 30min at 60∘C. The influence of reaction temperature, reaction time, reactants molar ratio, Si/Fe ratio and amount of catalyst were investigated.

  3. Computerized Biophysical Data Acquisition System for Motion Sickness Studies.

    DTIC Science & Technology

    1984-12-01

    biofeedback in Autogenic Feedback Training (AFT). Dr. Patricia Cowings of 1- 1 NASA-Ames Research Center has also successfully used AFT in her studies (7...analysis can be completed. Summary of Current Knowledge Researchers have approached the problem of motion sick- ness in several ways. One approach is to...that the technique is not "black magic" (17). Despite apparent successes by Dr. Levy and others, notably Dr. Patricia Cowings of the NASA-Ames Research

  4. Energy-Efficient High-Performance Routers

    DTIC Science & Technology

    2012-02-01

    award, the PI Dr. Sartaj Sahni, AFRL research scientist Dr. Gunasekaran Seetharaman, and University of Florida Ph.D. student Ms. Tania Banerjee...Sartaj Sahni, AFRL research scientist Dr. Gunasekaran Seetharaman, and University of Florida Ph.D. student Ms. Tania Banerjee-Mishra...Searching and Shift Redundancy Architecture, IJSSC, 40, 1, Jan 2005, 245-253. PC-DUOS+: A TCAM Architecture for Packet Classifiers Tania Banerjee

  5. Prostate Cancer Research Training in Health Disparities for Minority Undergraduates

    DTIC Science & Technology

    2014-04-01

    dentistry , one is already in a graduate program, and one more is in the process of applying to dental school. Two of our interns now hold research...23  Research Ethics   Dr. C. Freund     Introduction to  Biostatistics   Mr. Tan Ding     Digital Library   Ms. A. Whitehead  Informatics  Dr. F. Barnes...Training  Mr. Cedric Harville  Introduction to  Biostatistics   Dr. Vincent Agboto   Mentors’ Laboratory  Management of Cancer   Dr. L. Dent

  6. Dr. von Braun With Management Team

    NASA Technical Reports Server (NTRS)

    1961-01-01

    Dr. von Braun is shown in this photograph, which was probably taken in the early 1960s, with members of his management team. Pictured from left to right are, Werner Kuers, Director of the Manufacturing Engineering Division; Dr. Walter Haeussermarn, Director of the Astrionics Division; Dr. William Mrazek, Propulsion and Vehicle Engineering Division; Dr. von Braun; Dieter Grau, Director of the Quality Assurance Division; Dr. Oswald Lange, Director of the Saturn Systems Office; and Erich Neubert , Associate Deputy Director for Research and Development.

  7. Quantum Chemical Investigations of the Mechanism of Cationic Polymerization.

    DTIC Science & Technology

    1980-10-15

    of Naval Research I Code 260 Code AFRPL MKPA Arlingon, VA 22217 Edwards AFB, CA 93523 Attn: Mr. D. Siegel Attn: Dr. F. Roberto Office of Naval...495 Summer Street Bolling Air Force BaseBoston, MA 02210 Washington, DC 20332 Attn: Dr. L. Peebles Dr. A. Wood Air Force Office of 1~Scientific...Research 4 Office of Naval Research 1 Directorate of Aero- San Francisco Area Office space Sciences One HaITidie Plaza Suite 601 Bolling Air Force Base San

  8. ARC-2010-AC00-0168-9-Edit

    NASA Image and Video Library

    2000-11-03

    The Honorable George P. Schultz during a Visit and tour of Ames Research Center. Shown here from left to right are in the background Bill Berry, Ames Deputy Director, Dr. Tom Edwards, Chief, Aviation Systems Division, Front row, Dr. Sidney Drell, Staford University, former U S Secretary of State George Schultz, Dr Richard Haines, Senior Research Csientist, FFC at the Future Flight Central Simulator facility.

  9. Binaural Processing of Multiple Sound Sources

    DTIC Science & Technology

    2016-08-18

    Sound Source Localization Identification, and Sound Source Localization When Listeners Move. The CI research was also supported by an NIH grant...8217Cochlear Implant Performance in Realistic Listening Environments,’ Dr. Michael Dorman, Principal Investigator, Dr. William Yost unpaid advisor. The other... Listeners Move. The CI research was also supported by an NIH grant (“Cochlear Implant Performance in Realistic Listening Environments,” Dr. Michael Dorman

  10. Postdoctoral Fellow | Center for Cancer Research

    Cancer.gov

    A postdoctoral research position is available in the laboratory of Dr. Natasha Caplen in the Genetics Branch, National Cancer Institute, Center for Cancer Research. Dr. Caplen’s Laboratory conducts multidisciplinary and interdisciplinary research that uses RNAi and other DNA or RNA-based functional genomic technologies to interrogate specific aspects of the genetic,

  11. A TRIBUTE TO DR. WILLIAM PENN WATKINSON

    EPA Science Inventory

    Dr. William Penn Watkinson (known to colleagues as "Penn") of EPA¿s health research lab (National Health and Environmental Research Laboratory) of Research Triangle Park, North Carolina, died Wednesday, December 13 after a battle with lung cancer. He was a member of the Pulmonar...

  12. Threshold Tear Strength of some Molecular Networks.

    DTIC Science & Technology

    1981-04-03

    Attn: Dr. F. Roberto Office of Naval Research 1 AFSC Western Office Andrews AFB, Code DLFP 1030 East Green Street Washington, DC 20334 Pasadena, CA...of Chemical & Office Atmospheric Sciences 495 Summer Street Bolling Air Force Base Boston, MA 02210 Washington, DC 20332 Attn: Dr. L. Peebles Dr. A...Plaza Suite 601 Bolling Air Force Base San Francisco, CA 94102 Washington, DC 20332 Attn: Dr. P. A. Miller Attn: Dr. L. H. Caveny Defense Technical

  13. United States Air Force Summer Faculty Research Program - Management Report - 1985.

    DTIC Science & Technology

    1985-12-01

    Properties and Processing of a Dr. Vernon R. Allen Perfluorinated Polyalkylene Linked Polyimide 4 Quantifying Experience in the Cost Dr. Jihad A. Alsadek...Dr. Terrill D. Smith Compounds 127 Studies on Combustion of Liquid Fuel Dr. Siavash H. Sohrab Sprays in Stagnation Flows 128 Monitoring Environmental...Trafton Various Dinitrotoluenes and the Synthesis of Azo Compounds . 125 e 0 Ka 140 A Comparison of Measured and Calculated Dr. Larry Vardiman

  14. United States Air Force Research Initiation Program for 1988. Volume 2

    DTIC Science & Technology

    1990-04-01

    Specialty: Modeling and Simulation ENGINEERING AND SERVICES CENTER (Tyndall Air Force Base) Dr. Wayne A. Charlie Dr. Peter Jeffers (1987) Colorado State...Michael Sydor University of New Hampshire University of Minnesota Specialty: Systems Modeling & Controls Specialty: Optics, Material Science Dr. John...9MG-025 4 Modeling and Simulation on Micro- Dr. Joseph J. Feeley (1987) computers, 1989 760-7MG-070 5 Two Dimensional MHD Simulation of Dr. Manuel A

  15. Long Cycle Life Secondary Lithium Cells Utilizing Tetrahydrofuran.

    DTIC Science & Technology

    1984-04-01

    Rosenwasser) Code RD-I Washington, D.C. 20360 Washington, D.C. 20380 Naval Civil Engineering Laboratory 1 Dean William Tolles Attn: Dr. R. W. Drisko...Ocean Systems Center 11 apel Street San Diego, California 92152 wton, Massachusetts 02158 Dr. J. J. Auborn Dr. Adam Heller Bell Laboratories Bell...University Research Triangle Park, NC 27709 Evanston, Illinois 60201 Dr. William Ayers Dr. Aaron Fletcher ECD Inc. Naval Weapons Center P.O. Box 5357 Code

  16. Meet EPA Exposure Scientist and National Program Director Dr. Tina Bahadori

    EPA Pesticide Factsheets

    Dr. Tina Bahadori leads EPA's Chemical Safety for Sustainability research program. She is an exposure scientist with extensive expertise developing and managing research programs that integrate exposure with health sciences.

  17. Low Temperature Pulsed Plasma Deposition. Part 1. A New Technique for Thin Film Deposition with Complete Gas Dissociation.

    DTIC Science & Technology

    1988-04-12

    Res. Minneapolis Dr P Klocek Texas Instruments, Dallas Dr D N Lewis Naval Research Lab Dr S Musikant General Electric Co, Philadelphia Dr D Perry US...by utilising only a small fraction of the available reactants. Not only is this wasteful, limiting the method to reactants that are comparatively

  18. ARC Accomplishments and Collaborations Pursuing Challenges with Vision and Focus

    DTIC Science & Technology

    2010-05-10

    Navistar Defense LLC – Dr. Joe Lin, Eaton – Dr. Young Jae Kim, GM Hybrid Powertrain Eng. – Dr. Bin Wu, Mercedes - Benz Hybrid LLC – Dr. Vasilios Tsourapas...Fellows: 3 SAE, 4 ASME, 1 AAAS,1 IACM, 3 IEEE • 8 external Research and Educational Awards • 8 University Awards • 2 Young Scientists/Young Innovator

  19. S8DR shield examination

    NASA Technical Reports Server (NTRS)

    Mason, D. G.; Mccurnin, W. R.

    1973-01-01

    The SNAP 8 developmental reactor lithium hydride shield was examined after being irradiated for over 7000 hours at relatively low temperature. A crack was located in the seam weld of the containment vessel, probably the result of hot short cracking under thermal stress. The LiH was visually examined at two locations and its appearance was typical of low temperature irradiated LiH. The adherence of the chrome oxide emittance coating was found to be excellent.

  20. Globalization and the Diplomacy of Science

    ERIC Educational Resources Information Center

    Makhema, Joseph

    2010-01-01

    The closing keynote address given by Dr. Joseph Makhema highlights the important issues that need to be understood in international research collaborations. Dr. Makhema uses his extensive experience in international research collaborations to illustrate the various challenges that collaborating partners in international research may face. He…

  1. PREFACE: XX International School on Nuclear Physics, Neutron Physics and Applications (Varna2013)

    NASA Astrophysics Data System (ADS)

    Stoyanov, Chavdar; Dimitrova, Sevdalina

    2014-09-01

    The present volume contains the lectures and short talks given at the XX International School on Nuclear Physics, Neutron Physics and Applications. The School was held from 16-22 September 2013 in 'Club Hotel Bolero' located in 'Golden Sands' (Zlatni Pyasaci) Resort Complex on the Black Sea coast, near Varna, Bulgaria. The School was organized by the Institute for Nuclear Research and Nuclear Energy of Bulgarian Academy of Sciences. Co-organizer of the School was the Bulgarian Nuclear Regulatory Agency and the Bogoliubov Laboratory of Theoretical Physics of Joint Institute for Nuclear Research - Dubna. Financial support was also provided by the Bulgarian Ministry of Education and Science. According to the long-standing tradition the School has been held every second year since 1973. The School's program has been restructured according to our enlarged new international links and today it is more similar to an international conference than to a classical nuclear physics school. This new image attracts many young scientists and students from around the world. This year, 2013, we had the pleasure to welcome more than sixty distinguished scientists as lecturers. Additionally, twenty young colleagues received the opportunity to present a short contribution. Ninety-four participants altogether enjoyed the scientific presentations and discussions as well as the relaxing atmosphere at the beach and during the pleasant evenings. The program of the School ranged from latest results in fundamental areas such as nuclear structure and reactions to the hot issues of application of nuclear methods, reactor physics and nuclear safety. The main topics have been the following: Nuclear excitations at various energies. Nuclei at high angular moments and temperature. Structure and reactions far from stability. Symmetries and collective phenomena. Methods for lifetime measurements. Astrophysical aspects of nuclear structure. Neutron nuclear physics. Nuclear data. Advanced methods in nuclear waste treatment. Nuclear methods for applications. A special session in honor of the late Mario Stoitsov, was also part of the program. Many colleagues of Mario from all over the world came to Varna to pay tribute to this prominent scientist and loyal friend. Several colleagues contributed to the organization of the School. We would like to thank them and especially the Scientific Secretary of the School Dr Elena Stefanova and the members of the Organizing Committee Dr Dimitar Tarpanov and Peter Zivkov for their cordiality and high level assistance. We are also grateful to Dr Jacek Dobaczewski, who reached out to the collaborators of Mario Stoitsov on behalf of the conference. Sofia, 20 March 2014 Co-chair persons of the Organizing Committee Prof Dr Sc Ch Stoyanov Prof Dr Sc S Dimitrova Details of the committees are available in the PDF.

  2. Air and Space Power Journal. Volume 30, Number 2, Summer 2016

    DTIC Science & Technology

    2016-01-01

    Nicholas J. Thomas, USAF, PE Features Thinking beyond the Books ❙ 15 Sociological Biases of Our Military Institutions Ben Zweibelson Institutional ...Retired Editor, Strategic Studies Quarterly Air Force Research Institute Dr. Grant T. Hammond USAF Center for Strategy and Technology Dr. Dale L...Hayden Air Force Research Institute Col S. Clinton Hinote Military Fellow Council on Foreign Relations Dr. Thomas Hughes USAF School of Advanced Air and

  3. Draft environmental impact statement siting, construction, and operation of New Production Reactor capacity. Volume 4, Appendices D-R

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1991-04-01

    This Environmental Impact Statement (EIS) assesses the potential environmental impacts, both on a broad programmatic level and on a project-specific level, concerning a proposed action to provide new tritium production capacity to meet the nation`s nuclear defense requirements well into the 21st century. A capacity equivalent to that of about a 3,000-megawatt (thermal) heavy-water reactor was assumed as a reference basis for analysis in this EIS; this is the approximate capacity of the existing production reactors at DOE`s Savannah River Site near Aiken, South Carolina. The EIS programmatic alternatives address Departmental decisions to be made on whether to build newmore » production facilities, whether to build one or more complexes, what size production capacity to provide, and when to provide this capacity. Project-specific impacts for siting, constructing, and operating new production reactor capacity are assessed for three alternative sites: the Hanford Site near Richland, Washington; the Idaho National Engineering Laboratory near Idaho Falls, Idaho; and the Savannah River Site. For each site, the impacts of three reactor technologies (and supporting facilities) are assessed: a heavy-water reactor, a light-water reactor, and a modular high-temperature gas-cooled reactor. Impacts of the no-action alternative also are assessed. The EIS evaluates impacts related to air quality; noise levels; surface water, groundwater, and wetlands; land use; recreation; visual environment; biotic resources; historical, archaeological, and cultural resources; socioeconomics; transportation; waste management; and human health and safety. The EIS describes in detail the potential radioactive releases from new production reactors and support facilities and assesses the potential doses to workers and the general public. This volume contains 15 appendices.« less

  4. Sarilumab for the treatment of rheumatoid arthritis.

    PubMed

    Cooper, Simon

    2016-01-01

    Simon Cooper has >18 years of global experience in the pharmaceutical industry. He joined Sanofi in July 2014 as the Vice President, Global Project Head. In his current position at Sanofi, Dr Cooper is responsible for the clinical development of sarilumab and the worldwide submission in rheumatoid arthritis. He joined Sanofi after serving as the Global Program Medical Director at Novartis since 2012. In this role, Dr Cooper acted as the clinical lead for secukinumab psoriasis submission. Prior to Novartis, Dr Cooper held various posts at Human Genome Sciences, USA, including Executive Director of Clinical Research, Senior Director of Clinical Research and Director of Clinical Research. During his tenure at Human Genome Sciences, USA, Dr Cooper was involved in the submission of belimumab leading to its approval for SLE, and was responsible for its subsequent clinical development program. Dr Cooper has also previously held positions at MedImmune Ltd, UK, Roche, Napp Pharmaceutical Research Ltd, Wyeth Research and Medeval Ltd. In these roles, his responsibilities ranged from medical oversight of clinical trials to medical support for commercial, medical affairs and business development. He received a Bachelor of Medicine and Bachelor of Surgery from University of Newcastle upon Tyne Medical School.

  5. Demand Response Advanced Controls Framework and Assessment of Enabling Technology Costs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Potter, Jennifer; Cappers, Peter

    The Demand Response Advanced Controls Framework and Assessment of Enabling Technology Costs research describe a variety of DR opportunities and the various bulk power system services they can provide. The bulk power system services are mapped to a generalized taxonomy of DR “service types”, which allows us to discuss DR opportunities and bulk power system services in fewer yet broader categories that share similar technological requirements which mainly drive DR enablement costs. The research presents a framework for the costs to automate DR and provides descriptions of the various elements that drive enablement costs. The report introduces the various DRmore » enabling technologies and end-uses, identifies the various services that each can provide to the grid and provides the cost assessment for each enabling technology. In addition to a report, this research includes a Demand Response Advanced Controls Database and User Manual. They are intended to provide users with the data that underlies this research and instructions for how to use that database more effectively and efficiently.« less

  6. 78 FR 12092 - John V. Scalera; Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ... from both Dr. C. and Dr. M. Tr. 259-64. According to Respondent, Dr. C. is an orthopedic surgeon who... professional practice or research.''). \\14\\ It is also noted that Respondent has not been convicted of an...

  7. 1000424

    NASA Image and Video Library

    2010-03-16

    L TO R: DR. FRANCIS CHIARAMONTE, PROGRAM EXECUTIVE FOR PHYSICAL SCIENCES, ISS RESEARCH PROJECT, NASA HEADQUARTERS; DR. RAYMOND CLINTON, ACTING MANAGER FOR SCIENCE AND MISSION SYSTEMS OFFICE, NASA MARSHALL; DR. FRANK SZOFRAN, MICROGRAVITY MATERIALS SCIENCE PROJECT MANAGER AND DISCIPLINE SCIENTIST MATERIALS AND PROCESSES LABORATORY AT MSFC.

  8. Validation of Biomarkers for Prostate Cancer Prognosis

    DTIC Science & Technology

    2013-10-01

    prostate cancer research community for testing candidate biomarkers. Groups using the resource include Dr. Jeremy Squire, Dr. Gustavo Ayala, and Dr...Ferrari, Javier Hernandez , Antonio Hurtado-Coll, Kyle Kuchinsky, Janet Liew, Rosario Mendez-Meza, Elizabeth Smith, Imelda Tenggarra, Xiaotun Zhang

  9. Sharon Savage Appointed DCEG Clinical Director

    Cancer.gov

    Dr. Sharon Savage has been named as the new Clinical Director for DCEG, responsible for patient safety, research integrity, and responsible stewardship of research funding for all DCEG clinical activities. Learn more about Dr. Savage’s appointment

  10. Environmental Impact Research Program: Visual Resources Assessment Procedure for US Army Corps of Engineers

    DTIC Science & Technology

    1988-03-01

    32264. Technical Monitors were Dr. John Bushman and Mr. David P. Buelow, OCE, and Mr. Dave Mathis, Water Resources Support Center, Fort Belvoir, Va. The...Manager for EIRP was Dr. Roger T. Saucier. Dr. John Harrison was Chief, EL. The report was written by Dr. Smardon, Dr. Palmer, Mr. Knopf, Ms. Grinde...Riverfront area will continue. Historic Mill District projects and establishment of the Riverside Parkway System will further unify S the Riverfront

  11. High Performance Embedded Computing Software Initiative (HPEC-SI)

    DTIC Science & Technology

    2004-08-20

    models , methodologies, and standards i i i i i i i i i l i i i i l , l i , Slide-5 www.hpec-si.org MITRE AFRLMIT Lincoln...Linderman AFRL Dr. Richard Games MITRE Mr. John Grosh OSD Mr. Bob Graybill DARPA/ITO Dr. Keith Bromley SPAWAR Dr. Mark Richards GTRI Dr. Jeremy Kepner...Capt. Bergmann AFRL Dr. Tony Skjellum MPISoft ... Advanced Research Mr. Bob Graybill DARPA • Partnership with ODUSD(S&T), Government Labs, FFRDCs

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Samios,N.P.

    The ninth evaluation of the RIKEN BNL Research Center (RBRC) took place on Nov. 17-18, 2008, at Brookhaven National Laboratory. The members of the Scientific Review Committee (SRC) were Dr. Dr. Wit Busza (Chair), Dr. Miklos Gyulassy, Dr. Akira Masaike, Dr. Richard Milner, Dr. Alfred Mueller, and Dr. Akira Ukawa. We are pleased that Dr. Yasushige Yano, the Director of the Nishina Institute of RIKEN, Japan participated in this meeting both in informing the committee of the activities of the Nishina Institute and the role of RBRC and as an observer of this review. In order to illustrate the breadthmore » and scope of the RBRC program, each member of the Center made a presentation on his/her research efforts. This encompassed three major areas of investigation, theoretical, experimental and computational physics. In addition the committee met privately with the fellows and postdocs to ascertain their opinions and concerns. Although the main purpose of this review is a report to RIKEN Management (Dr. Ryoji Noyori, RIKEN President) on the health, scientific value, management and future prospects of the Center, the RBRC management felt that a compendium of the scientific presentations are of sufficient quality and interest that they warrant a wider distribution. Therefore we have made this compilation and present it to the community for its information and enlightenment.« less

  13. Study of Vibrational Energy Transfer at a Surface by a Time-of-Flight Method.

    DTIC Science & Technology

    1983-07-31

    82174* - *-. L7 .i.&. I- I OD(D SOI x O 1 6/81 INIT DISTRIBUTION LIST July 31, 1983 No. Copies No. Copies Dr. L.V. Schmidt 1 Dr. F. Roberto 1 Assistant...of Scientific Dr. A.L. Slafkosky 1Research Scientific Advisor Directorate of Aerospace Sciences Commandant of the Marine Corps Bolling Air Force Base...Research Research Code 432 Directorate of Chemical Sciences Arlington, VA 22217 Bolling Air Force Base Washington, D.C. 20332Mr. David SiegelI Office of

  14. Dr. Stefan Ambs: Increasing Diversity in Cancer Research: One Lab at a Time

    Cancer.gov

    As part of the series “Increasing Diversity in Cancer Research,” CRCHD interviewed Dr. Stefan Ambs, an investigator at NCI’s Center for Cancer Research, who is using novel approaches to discover gene differences in the tumors of African American patients.

  15. Responsiveness of a Neuromuscular Recovery Scale for Spinal Cord Injury: Inpatient and Outpatient Rehabilitation

    DTIC Science & Technology

    2013-10-01

    Velozo’s research focus is on the development of functional outcome measures using Rasch measurement theory. Dr. Velozo’s research team has...functional outcome measures using Rasch measurement theory. Dr. Velozo’s research team has developed computerized adaptive measurement of physical

  16. Interdisciplinary Research Training in Breast Cancer

    DTIC Science & Technology

    2006-07-01

    McCorkle and Knobf, the study was published in Journal of Medical Internet Research . • Dr. LaCoursiere had begun an ongoing collaboration with Dr...patients’ self-reported attitudes about the Internet. Journal of Medical Internet Research , 7(3), e22. • LaCoursiere, S. P., & Sarkar, M. (2004

  17. Review of Two-Stage FEL Research at KMS Fusion.

    DTIC Science & Technology

    1983-01-21

    vi ty Research and Engineering Technical Library (3 copies) NST. Station, MS 39529 Information Office Library Branch The Pentagon Naval Explosive ...Shafer Associates, Inc. Office of Naval Research 10 Lakeside Office Park Arlington, VA 22217 Wakefield, MA 01880 Dr. Don Prosnitz Dr. T. C. Marshall

  18. Metastasis Research Society VII International Congress (Part II). 7-10 October 1998, San Diego, CA, USA.

    PubMed

    Chambers, A F

    1999-02-01

    The Metastasis Research Society (MRS) has held its International Congress every two years since 1986, and alternates between European and North American meeting venues. The next MRS International Congress will be held in London, UK in the year 2000, and will be hosted by the current MRS President, Dr. Suzanne Eccles (Institute of Cancer Research, Sutton, UK). Dr. Eccles took over from the out-going President, Dr. William Stetler-Stevenson (National Institutes of Health, Bethesda, MD, USA), at the San Diego meeting. Information on joining the Metastasis Research Society, which includes a subscription to the Society's journal, Clinical and Experimental Metastasis, can be obtained from Dr. Eccles (suzan@icr.ac.uk) or from the newly-elected Secretary/Treasurer Dr. Danny Welch (Hershey, PA, USA; drw9@psu.edu). The meeting was organized by Darwin Medical Communications Ltd (Gill Heaton, Oxford, UK), who have placed the full program on the meeting web site (http:@www.sparks.co.uk/mrs). It is envisaged that full abstracts of all the presentations will be placed on the Metastasis Research Society web site, which is currently under construction. Corporate sponsors for the San Diego meeting included Agouron Pharmaceuticals, Becton Dickinson & Co, Zeneca Pharma SA, Schering AG, AntiCancer Inc, Oncogene Research Products, Daiichi Seiyaku Co Ltd and Novartis Pharma AG.

  19. Interview with Janet Woodcock.

    PubMed

    Woodcock, Janet

    2010-09-01

    Dr Janet Woodcock is the Director of the US FDA's Center for Drug Evaluation and Research. Dr Woodcock has held various positions within the FDA's Office of the Commissioner from October 2003 until 1 April 2008, as Deputy Commissioner and Chief Medical Officer, Deputy Commissioner for Operations and Chief Operating Officer and Director of the Critical Path Programs. She oversaw scientific and medical regulatory operations for the FDA. Dr Woodcock served as Director of the Center for Drug Evaluation and Research at the FDA from 1994 to 2005. She previously served in other positions at the FDA, including Director of the Office of Therapeutics Research and Review and Acting Deputy Director of the Center for Biologics Evaluation and Research. Dr Woodcock received her MD from Northwestern Medical School (IL, USA), and completed further training and held teaching appointments at the Pennsylvania State University (PA, USA) and the University of California in San Francisco (CA, USA). She joined the FDA in 1986.

  20. Drug-resistant tuberculosis clinical trials: proposed core research definitions in adults.

    PubMed

    Furin, J; Alirol, E; Allen, E; Fielding, K; Merle, C; Abubakar, I; Andersen, J; Davies, G; Dheda, K; Diacon, A; Dooley, K E; Dravnice, G; Eisenach, K; Everitt, D; Ferstenberg, D; Goolam-Mahomed, A; Grobusch, M P; Gupta, R; Harausz, E; Harrington, M; Horsburgh, C R; Lienhardt, C; McNeeley, D; Mitnick, C D; Nachman, S; Nahid, P; Nunn, A J; Phillips, P; Rodriguez, C; Shah, S; Wells, C; Thomas-Nyang'wa, B; du Cros, P

    2016-03-01

    Drug-resistant tuberculosis (DR-TB) is a growing public health problem, and for the first time in decades, new drugs for the treatment of this disease have been developed. These new drugs have prompted strengthened efforts in DR-TB clinical trials research, and there are now multiple ongoing and planned DR-TB clinical trials. To facilitate comparability and maximise policy impact, a common set of core research definitions is needed, and this paper presents a core set of efficacy and safety definitions as well as other important considerations in DR-TB clinical trials work. To elaborate these definitions, a search of clinical trials registries, published manuscripts and conference proceedings was undertaken to identify groups conducting trials of new regimens for the treatment of DR-TB. Individuals from these groups developed the core set of definitions presented here. Further work is needed to validate and assess the utility of these definitions but they represent an important first step to ensure there is comparability in clinical trials on multidrug-resistant TB.

  1. Healthcare reform in the Middle East and the USA.

    PubMed

    Younis, Mustafa Z

    2017-01-01

    Mustafa Z Younis speaks to Laura Dormer, Commissioning Editor: Dr Mustafa Z Younis is an internationally recognized scholar and was a member of the Executive Committee of the International Society for Research of Healthcare Financial Management. Dr Younis has authored and published over 200 articles, abstracts and presentations in refereed journals and meetings, and has presented at national and international conferences. Dr Younis has administrative experience as Senior Adviser for the President at Zirve University, Turkey and as Chair of the Department of Health Policy and Management at Florida International University (FL, USA) where he led the accreditation efforts for the Healthcare Management Program. Dr Younis has a history of playing visible roles on the editorial boards of journals as Chief Editor, Guest Editor and Editorial board member of leading journals such as Journal of International Medical Research, Journal of Health Care Finance, Inquiry, Journal of Health and Human Services Administration, Journal of Public Budgeting, Accounting and Financial Management. Dr Younis is a frequent speaker for both academic and professional audiences. His talks often feature his latest research and work in progress as well as cross-industry trends and strategy implications. He has provided workshops and presentation for wide organizations. His research and findings applied to for-profit, non-profit settings, and government. Dr Younis has consulted with several organizations on healthcare finance, and economics. Dr Younis is often invited to speak about the challenges in the healthcare industry and other related topics to health economics, finance, and research. He has presented topics such as, healthcare reform, ownership structure, profitability, unit cost, payment system and efficiency in management, at a variety of forums and conferences in Europe, Asia and Middle East.

  2. Research in Energetic Compounds.

    DTIC Science & Technology

    1980-01-01

    Copies No. Copies Dr. L.V. Schmidt 1 [r. F. Roberto Assistant Secretary of the Navy Code AFRPL HKPA (R,E, and S) Room 5E 731 Edwards AF6, CA 93523...Force Office of Sciertific Dr. Richard S. Miller 10 Research Office of Naval Research Directorate of Chemical Sciences Arlington, VA 22217 Bolling Air

  3. Dr. Dinah Singer: Increasing Diversity in Cancer Research: One Lab at a Time

    Cancer.gov

    As part of the series “Increasing Diversity in Cancer Research,” CRCHD spoke with Dr. Dinah Singer, Director of NCI’s Division of Cancer Biology, about training and mentorship, and the role it plays in attracting and retaining students and investigators underrepresented in cancer research.

  4. The Logic of the Theoretical and Practical Products of Design Research

    ERIC Educational Resources Information Center

    Easterday, Matthew W.; Rees Lewis, Daniel G.; Gerber, Elizabeth M.

    2016-01-01

    Design research (DR) promises to simultaneously solve practical problems of education and develop theory to guide future interventions. However, educational DR remains paradigmatically underdeveloped, making it difficult to train new researchers, to agree upon what makes a theoretical contribution, and to promise clear outputs to funders--all of…

  5. Adult Brain and Spine Tumor Research - Facebook Live Event

    Cancer.gov

    Chief, Dr. Mark Gilbert and Senior Investigator, Dr. Terri Armstrong, of the NCI Center for Cancer Research, Neuro-Oncology Branch, will be joined by moderator and Chief Executive Officer, David Arons of the National Brain Tumor Society led a discussion on adult brain and spine tumor research and treatment.

  6. Adult Brain and Spine Tumor Research and Development

    Cancer.gov

    Chief, Dr. Mark Gilbert and Senior Investigator, Dr. Terri Armstrong, of the NCI Center for Cancer Research, Neuro-Oncology Branch, will be joined by moderator and Chief Executive Officer, David Arons of the National Brain Tumor Society led a discussion on adult brain and spine tumor research and treatment.

  7. Discussion-preliminary review of the safety aspects of the crossunder line, Project CG-884. Volume 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jones, S.S.

    1960-12-19

    In order to reduce both charge-discharge shutdown time and the number of manhours of radiation exposure, Project CGI-884 is being completed at the B, D, DR, F and R Reactors. This consists essentially of installing a large drain line at the bottom of one rear reactor riser. This drain line passes to a control valve and then to the effluent line beyond the downcomer. This system by-passes the crossover downcomer part of the effluent system and eliminates the need for intermittent rear crossheader valving during reactor charge-discharge procedures. Two aspects of this system have been considered, its basic design requirements,more » and operating restrictions to ensure adequate process tube cooling. Because of the complexity of the reactor flow system approximate solutions were used to compare different methods or degrees of operation and establish limits. Despite these approximations, there was sufficient difference in the case results to justify the specific conclusions presented in this report. This report should serve the dual purpose of providing design requirements for the crossunder and also providing the technical criteria necessary for the operating standards for the use of this new system.« less

  8. A Comparison of the Effects of Random Versus Fixed Order of Item Presentation Via the Computer

    DTIC Science & Technology

    1989-02-01

    Copies) Dr. Hans Crombag Dr. Stephen Dunbar University of Leyden Lindquist Center Education Research Center for Measurement Boerhaavelaan 2 University of...Iowa 2334 EN Leyden Iowa City, IA 52242 The NETHERLANDS Dr. James A. Earles Dr. Timothy Davey Air Force Human Resources Lab Educational Testing...Montague 4401 Ford Avenue NPRDC Code 13 P.O. Box 16268 San Diego, CA 92152-6800 Alexandria, VA 22302-0268 Ms. Kathleen Moreno Dr..William L. Maloy

  9. Guidon-Watch: A Graphic Interface for Viewing a Knowledge-Based System.

    DTIC Science & Technology

    1985-08-01

    Research Center Department of the Navy University of Illinois Boerhaavelaan 2 Washington, DO 20350-1000 Department of Cmpuer Science2334 EN Leyden 1304...Dr. William L. Maloy 270 Crown Street Pittsburgh, PA 15213 Chief of Naval Education New Haven, CT 06510 and Training Dr. Kathleen IaPiana Naval Air...Mclean, VA 22102 1250 West 6th Street Campus Box 345 San Diego, CA 92101 Boulder, CO 8D302 Dr. Aan M. lesgoldlearning M.D Center Dr. Kathleen McKeown Dr

  10. Effects of Whole and Partial Body Exposure to Dry Heat on Certain Performance Measures.

    DTIC Science & Technology

    1981-05-01

    Robert Bachert who assisted with the statistical analyses; and he acknowledges the support of the Lite Mr. George C. Frost for his advice on the...of the study and interpretation of data: Dr. Arthur L Dudycha, Dr. Barry H. Kantowitz, Dr. N. M. Downie, Dr. Ernest J. McCormick, and Dr. Robert D...D., Summers, W. C., & Smedley , D. C., November 1974, Evaluation of a water- cooled helmet liner (AMRL-TR-74-135). Aerospace Medical Research

  11. Successful Education Research: Guidelines for Getting Going, Getting Funded and Getting Published

    ERIC Educational Resources Information Center

    Deacon, Roger; Parker, Ben

    2009-01-01

    As part of the Teacher Education Research and Development Programme (TEP), a project focusing on "Stimulation of practice-based teacher education research", was undertaken by Dr. Roger Deacon and Dr. Ben Parker, in conjunction with the Centre for Education Policy Development (CEPD). As part of the project, a set of research guidelines…

  12. A life with horses: it's been a great ride!

    PubMed

    Antczak, Douglas F

    2012-07-15

    In 2010 Doug Antczak was the recipient of the Distinguished Veterinary Immunologist Award of the Veterinary Immunology Committee of the International Union of Immunological Societies. Dr. Antczak is the Dorothy Havemeyer McConville Professor of Equine Medicine at the Baker Institute for Animal Health in the College of Veterinary Medicine at Cornell University. His research focuses on immunological and genetic aspects of the fetal-maternal relationship in the horse. This includes studies of major histocompatibility complex (MHC) genes and molecules, the regulation of their expression in the placenta, the composition and function of uterine lymphocytes, and alterations in maternal immune reactivity during pregnancy. For this research Dr. Antczak developed a herd of purpose-bred horses selected for homozygosity at the MHC. These horses are a unique genetic resource in equine immunology. During his career Dr. Antczak has mentored over 20 graduate students and post-doctoral fellows, many of whom have gone on to independent careers in immunology research. Dr. Antczak has made contributions to equine immunology, genetics, and reproduction, and collaborated widely with scientists in each of these disciplines. Through his relationship with the Havemeyer Foundation, Dr. Antczak has been a catalyst for cooperative research through a series of Havemeyer Foundation Workshops initiated over 25 years ago. Since 1995 he has been a principal participant in the international Horse Genome Project collaboration furthering his equine immunology research through genomic applications. In 2009 Dr. Antczak was inducted into the University of Kentucky's Equine Research Hall of Fame. Copyright © 2012 Elsevier B.V. All rights reserved.

  13. At NCI, Supporting the Best Science

    Cancer.gov

    Yesterday, at the AACR annual meeting, Dr. Doug Lowy spoke directly to the research community about his goals as NCI Acting Director. Dr. Lowy said that he plans to continue many of the programs launched by his predecessor, Dr. Harold Varmus, and to sharp

  14. Maximizing the Prospects for Progress Against Cancer

    Cancer.gov

    The 2018 American Society of Clinical Oncology annual meeting featured numerous, potentially practice changing research findings, according to NCI Director Dr. Norman Sharpless. In this Cancer Currents post, Dr. Sharpless discusses the rapid pace of progress in cancer research.

  15. Veterinary Research Manpower Development for Defense

    DTIC Science & Technology

    2008-09-01

    Geographic Risk Factors for Disease Transmission between Livestock and Elephants in Chitwan, Nepal Philip Gerwin V’11 Dr. Mann The Role of...loss for the farmer, but also has negative impact on livelihoods. Using the Rose Bengal Agglutination Test, this study tested 163 goats to determine...and Mycobacterium avium in captive elephants in Nepal Trainee: Tierra Wilson Mentors: Dr. Gretchen Kaufman, Dr. Jean Mukherjee and Dr. Donna

  16. Twenty years of Medicare and Medicaid: Covered populations, use of benefits, and program expenditures

    PubMed Central

    Gornick, Marian; Greenberg, Jay N.; Eggers, Paul W.; Dobson, Allen

    1985-01-01

    Marian Gornick is Director, Division of Beneficiary Studies, in the Office of Research, Health Care Financing Administration. She has been involved in research studies relating to Medicare and Medicaid since the programs were first implemented. Jay N. Greenberg is on the faculty of the Heller Graduate School, Brandeis University. Dr. Greenberg serves as the Associate Director for Research of the school's Health Policy Center. Paul W. Eggers is Chief, Program Evaluation Branch, in the Office of Research, Health Care Financing Administration (HCFA). Dr. Eggers’ research activities involve the evaluation of the impact of HCFA programs on the beneficiaries. Allen Dobson is Director, Office of Research, Health Care Financing Administration. Dr. Dobson is responsible for directing the planning and development of the Agency's research agenda. PMID:10311371

  17. 78 FR 26811 - Dow Chemical Company, Dow TRIGA Research Reactor; License Renewal for the Dow Chemical TRIGA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... Research Reactor; License Renewal for the Dow Chemical TRIGA Research Reactor; Supplemental Information and... 20, 2012 (77 FR 42771), ``License Renewal for the Dow Chemical TRIGA Research Reactor,'' to inform... Chemical Company which would authorize continued operation of the Dow TRIGA Research Reactor. The notice...

  18. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    ScienceCinema

    Goyal, Amit [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2018-04-27

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy 100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

  19. Directory of Aircraft Survivability Specialists and Their Affiliations

    DTIC Science & Technology

    1980-12-01

    AnalysisOps Research WILLIAMS RESEARCH CORP 2280 West Maple Rd Walled Lake, MT 48088 SCHNYDER, Sidney A. (313) 624-5200 Gas turbine droneSupervisor of...AAWP-3 (513) 255-5076 reduction PELTON , Dr. Edward AV 785-5076 Radar cross section AFWAL/AAWP-3 (513) 255-5076 Reduction technology SANDERSON, Dr...Aberdeen Proving Gd, MD 21005 AV 927-3902 AV 283-4643 (804) 878-3902 (301) 278-4643 PELTON , Dr. Edward PARKER, Preston L. AFWAL/AAWP-3 AD/SESS Air

  20. Application of Component Scoring to a Complicated Cognitive Domain

    DTIC Science & Technology

    1985-05-15

    Command (N-5) NAS Pensacola, FL 32508 Dr. John M. Eddins S..""*University of IllinoisDr. Hans Crombag 252 Engineering Research University of Leyden ...Laboratory Education Research Center 103 South Mathews Street Boerhaavelaan 2 Urbana, IL 61801 2334 EN Leyden The NETHERLANDS V.- University of Illinois...Naval Air Station Pensacola, FL 32508 Ms. Kathleen Moreno Navy Personnel R&D Center Dr. Gary Marco Code 62 Stop 31-E San Diego, CA 92152 Educational

  1. Influence of p53 status on the effects of boron neutron capture therapy in glioblastoma.

    PubMed

    Seki, Keiko; Kinashi, Yuko; Takahashi, Sentaro

    2015-01-01

    The tumor suppressor gene p53 is mutated in glioblastoma. We studied the relationship between the p53 gene and the biological effects of boron neutron capture therapy (BNCT). The human glioblastoma cells; A172, expressing wild-type p53, and T98G, with mutant p53, were irradiated by the Kyoto University Research Reactor (KUR). The biological effects after neutron irradiation were evaluated by the cell killing effect, 53BP1 foci assay and apoptosis induction. The survival-fraction data revealed that A172 was more radiosensitive than T98G, but the difference was reduced when boronophenylalanine (BPA) was present. Both cell lines exhibited similar numbers of foci, suggesting that the initial levels of DNA damage did not depend on p53 function. Detection of apoptosis revealed a lower rate of apoptosis in the T98G. BNCT causes cell death in glioblastoma cells, regardless of p53 mutation status. In T98G cells, cell killing and apoptosis occurred effectively following BNCT. Copyright© 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  2. Special Issue on Global Health Disparities Focus on Cancer.

    PubMed

    Lee, Haeok

    2016-01-01

    Haeok Lee, PhD, RN, FAAN who is a Korean-American nurse scientist, received her doctor al degree from the Nursing Physiology Department, College of Nursing, University of California, San Francisco (UCSF), in 1993, and her post doctor al training from College of Medicine, UCSF. Dr. Lee worked at Case Western Reserve University and University of Colorado Health Sciences Center. She has worked at the UMass Boston since 2008. Dr. Lee has established a long-term commitment to minority health, especially Asian American Pacific Islanders, as a community leader, community health educator, and community researcher, and all these services have become a foundation for her community-based participatory research. Dr. Lee's research addresses current health problems framed in the context of social, political, and economic settings, and her studies have improved racial and ethnic data and developed national health policies to address health disparities in hepatitis B virus (HBV) infections and liver cancer among minorities. Dr. Lee's research, which is noteworthy for its theoretical base, is clearly filling the gap. Especially, Dr. Lee's research is beginning to have a favorable impact on national and international health policies and continuing education programs directed toward the global elimination of cervical and liver cancer-related health disparities in underserved and understudied populations.

  3. ARC-2010-ACD10-0066-004

    NASA Image and Video Library

    2010-04-09

    Netherlands Memorandum of Record (MOR) agreement signing the NASA Ames Research Center, Mofffett Field, California. Signing the MOR are on left Dr. Louis B.J.Vertegaal, Director of Physical Sciences, Chemistry, and Advanced Chemical Technologies for Sustainability, of the Netherlands Organisation for Scientific Research (NWO) and on right Dr. S. Pete Worden, Director NASA Ames Research Center

  4. Automotive Research Center

    Science.gov Websites

    7, 2018, LA Times) Dr. Jason Siegel to chair IEEE Technical Committee on Automotive Controls (Feb 2018, IEEE) Dr. Anna Stefanopoulou on research of sustainable vehicle technologies (Jan 24, 2018, WEMU ) Stefanopoulou plenary at IEEE 56th CDC (Jan 17, 2018, ME) ARC Researchers at IEEE 56th Conf. Decision and

  5. Joint conference of iMEC 2015 (2nd International Manufacturing Engineering Conference & APCOMS 2015 (3rd Asia-Pacific Conference on Manufacturing Systems)

    NASA Astrophysics Data System (ADS)

    2016-02-01

    The iMEC 2015 is the second International Manufacturing Engineering Conference organized by the Faculty of Manufacturing, Universiti Malaysia Pahang (UMP), held from 12-14th November 2015 in Kuala Lumpur, Malaysia, with a theme "Materials, Manufacturing and Systems for Tomorrow". For the first time, iMEC is organized together with 3rd Asia- Pacific Conference on Manufacturing System (APCOMS 2015) which owned by Fakulti Teknologi Industri, Institut Teknologi Bandung (ITB), Indonesia. This is an extended collaboration between UMP and ITB to intensify knowledge sharing and experiences between higher learning institutions. This conference (iMEC & APCOMS 2015) is a platform for knowledge exchange and the growth of ideas, particularly in manufacturing engineering. The conference aims to bring researchers, academics, scientists, students, engineers and practitioners from around the world together to present their latest findings, ideas, developments and applications related to manufacturing engineering and other related research areas. With rapid advancements in manufacturing engineering, iMEC is an appropriate medium for the associated community to keep pace with the changes. In 2015, the conference theme is “Materials, Manufacturing and Systems for Tomorrow” which reflects the acceleration of knowledge and technology in global manufacturing. The papers in these proceedings are examples of the work presented at the conference. They represent the tip of the iceberg, as the conference attracted over 200 abstracts from Malaysia, Indonesia, Japan, United Kingdom, Australia, India, Bangladesh, South Africa, Turkey and Morocco and 151 full papers were accepted in these proceedings. The conference was run in four parallel sessions with 160 presenters sharing their latest finding in the areas of manufacturing process, systems, advanced materials and automation. The first keynote presentation was given by Prof. B. S. Murthy (IIT, Madras) on "Nanomaterials with Exceptional Properties Synthesized through Top Down Approach”, which was warmly welcomed by an eager and highly motivated audience. The second keynote speaker was Prof. Ir. Dradjad Irianto (ITB, Indonesia) on “Collaborative Manufacturing for Small-medium Enterprises”. The organizers are very grateful to them for supporting the conference and sharing their latest research results with the conference participants. The conference organizers would like to express our sincere gratitude and thanks to the honorary chairman Prof. Dato, Dr. Daing Nasir Ibrahim and Prof. Dr. Wan Azhar Wan Yusoff and organizing committee members of iMEC2015, Assoc. Prof. Dr. A.K. Prasada Rao (chairman), Dr. Ing. Mohd Azmir Mohd Azhari (co-chairman), and all committee members Assoc. Prof. Dr. Ahmad Razlan Yusoff, Assoc. Prof. Dr. Ismed Iskandar, Dr Noraini Mohd Razali, Dr Muhammed Nafis Osman Zahid, Dr Noor Mazni Ismail, Dr Izwan Ismail, Dr Zamzuri Hamedon, Dr Faiz Mohd Turan, Ms Suraya Sulaiman and secretariat Miss Zuryaty, Mrs Wan Norshihah, Mr. Mohd Khairulnazri and Mr Rafilah and also a million thanks to the steering committee from APCOMS Prof. Dr. Kadarsyah Suryadi, Prof. Dr. Bermawi, P. Iskandar, Prof. Dr. Abdul Hakim Halim, Prof. Dr. Dradjad Irianto, Dr. TMA Ari Samadhi, Ir. I Made Dana Tangkas and APCOMS organizing committee Prof. Dr. Abdul Hakim Halim (chair), Dr. Rachmawati Wangsaputra (co-chair) and other committee members Dr. Iwan Inrawan Wiratmadja, Dr. Anas Ma'ruf, Dr. Sukoyo and Dr. Wisnu Aribowo. The editorial board are indebted to all of the reviewers who were willing to spend their precious time in reviewing the papers. Thanks also to all who contributed direct or indirectly in making this conference a success, especially Mr. Mohd Khairulnazri in helping the editors complete the proceedings. Dr. Zamzuri Hamedon Editor in-chief iMEC & APCOMS 2015 Associate Editors 1. Assoc. Prof. Dr. A.K. Prasada Rao 2. Assoc. Prof. Dr. Ahmad Razlan Yusoff 3. Dr. Ing. Mohd Azmir Mohd Azhari 4. Dr. Muhammed Nafis Osman Zahid 5. Dr. Faiz Mohd Turan

  6. The history of Patuxent: America’s wildlife research story

    USGS Publications Warehouse

    Perry, Matthew C.

    2017-01-18

    This report, based on a symposium held on October 13, 2011, at the National Wildlife Visitor Center at the Patuxent Research Refuge in Laurel, MD, documents the history of the Patuxent Research Refuge and the Patuxent Wildlife Research Center, collectively known as Patuxent. The symposium was one of the many activities occurring at that time to celebrate the 75th anniversary of the creation of the Patuxent Research Refuge in 1936. The Patuxent Wildlife Research Center is located at the refuge, and the research center director, Dr. Gregory J. Smith, with great enthusiasm, personally supervised all aspects of the celebration. The symposium was coordinated by Dr. Matthew C. Perry, the editor of this report, with Dr. Smith’s strong support. The refuge and the research center have been essentially synonymous for the almost 80 years of their history.

  7. Antennas and Electromagnetics Instrumentation for Research and Education

    DTIC Science & Technology

    2016-06-01

    Antennas and Electromagnetics Instrumentation for Research and Education The objective of this proposal is to enhance the instrumentation of FIU’s... ElectroMagnetics Lab (EMLab) directed by Dr. Georgakopoulos and create a state-of-the art lab that will support the following: (a) Dr. Georgakopoulos...funded research on reconfigurable antennas and wireless power transfer, (b) other research on advanced electromagnetic technologies that support

  8. LDRD 2013 Annual Report: Laboratory Directed Research and Development Program Activities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bookless, W.

    This LDRD project establishes a research program led by Jingguang Chen, who has started a new position as a Joint Appointee between BNL and Columbia University as of FY2013. Under this project, Dr. Chen will establish a new program in catalysis science at BNL and Columbia University. The LDRD program will provide initial research funding to start research at both BNL and Columbia. At BNL, Dr. Chen will initiate laboratory research, including hiring research staff, and will collaborate with the existing BNL catalysis and electrocatalysis research groups. At Columbia, a subcontract to Dr. Chen will provide startup funding for hismore » laboratory research, including initial graduate student costs. The research efforts will be linked under a common Catalysis Program in Sustainable Fuels. The overall impact of this project will be to strengthen the BNL catalysis science program through new linked research thrusts and the addition of an internationally distinguished catalysis scientist.« less

  9. Performance Envelopes and Optimal Appropriateness Measurement.

    DTIC Science & Technology

    1984-12-01

    20370 Dr. Hans Crombag University of Leyden Mr. Raymond E. Christal Education Research Center AFHRL/MOE Boerhaavelaan 2 Brooks AFB, TX 78235 2334 EN... Leyden The NETHERLANDS Dr. Norman Cliff Department of Psychology CTB/McGraw-Hill Library Univ. of So. California 2500 Garden Road University Park...Psychology Dr William Montague University of Western Australia NPRDC Code 13 Nedlands W.A. 6009 San Diego, CA 92152 AUSTRALIA Ms. Kathleen Moreno Dr

  10. Evaporation from Sand

    DTIC Science & Technology

    1992-04-01

    Instituuts Advies R2ad PML Prof. dr. U.A.Th. Brinkanl~ 36. Direactur van het Medisch Biologisch Laboratorium TNO Prof.Dr. W.R.F. Notten 37. Directeur...Grootsdialige Rampenbestrijdcing Ministerie van Binnenlandsc Zaken Drs. H. Evers 9. Adviseur van het Prins Maurits Laboratorium TWO Prot. Dr. J.M. van...Rossum, 10. Adyisew, van het Prins Maurits Laboratorium TWO Chernisdie Research Prof.Dr. G. Dijkstra 11. H~ur. NBC DMKIJOMAT/KIO Ir. AAM. Slagveer 12

  11. Making Aggressive Prostate Cancer Quiescent by Abrogating Cholesterol Esterification

    DTIC Science & Technology

    2016-10-01

    team has been assembled , with expertise in spectroscopic imaging & nanomedicine (Dr. J. X. Cheng, PI), biochemistry (Dr. X. Liu, co-PI), and prostate...was approved in 2004 as the first- line cytotoxic chemotherapy owing to a modest increase in overall survival compared to mitoxantrone. Since 2010...interdisciplinary research team has been assembled , with expertise in spectroscopic imaging & nanomedicine (Dr. J. X. Cheng, PI), biochemistry (Dr. X. Liu, co-PI

  12. Low Prevalence of HIV Infection in Djibouti - Has the AIDS Epidemic Come to a Stop at the Horn of Africa?

    DTIC Science & Technology

    1989-01-01

    Abbatte’ Ministre de la Sante ernmost part of the Horn of Africa. Its inhabitants publique : Dr Albert; WHO, Djibouti: Dr Wassef; H6pital belong to...Research Unit No. 3, FPO, New York, NY entreprise : Dr Said; Cabinet Medical: Dr Rodier" and Mr 09527-1600, USA. Adel; Dispensaire de Randa: Dr Qufz&k...41 at the Service Medical Inter- entreprise , at the Nation- hospital patients with a disease compatible with al Army Health Centre, at the Service

  13. Analytical Representations of Blast Damage for Several Types of Targets

    DTIC Science & Technology

    1978-10-01

    Office Box 195 Washington, D.C. Oak Ridge, Tennessee 37830 Mr. Eugene Kopf (1) Dr. Richard Garwin (1) Defense Advanced Research Projects IBM Fellow...Ridge National Laboratory Center for Planning & Research, Inc. Post Office Box X 750 Welch Road Oak Ridge, Tennessee 37830 Palo Alto, California 94304 Dr...Dr. Conrad V. Chester(i Oak Ridge National Laboratory Building 450C-S, Roan S-24o0 Post Office Box E O •k Ridge, Tennessee 37830 Institute for Defense

  14. Threshold Tear Strength of Elastomers.

    DTIC Science & Technology

    1982-04-01

    O 0 0 C~j C-J C7,) 0DY 122 DISTRIBUTION LIST No. Cooes No. Cooies Dr. L.V. Schmidt I Dr. F. Roberto 1 ’Assistant Secretary of the Navy Code AFRPL MKPA...Research Scientific Advisor Directorate of Aerospace Sciences Commandant of the Marine Corps Bolling Air Force Base Code RD-i Washington, D.C. 20332...Directorate of Chemical Sciences Arlington, VA 22217 Bolling Air Force Base Washington, D.C. 20332 Mr. David Siegel D Office of Naval Research Dr. John S

  15. Directory of Researchers for Manpower, Personnel, Training, and Human Factors

    DTIC Science & Technology

    1998-03-01

    Cambridge, MA Bohres, G Naval Surface Warfare Center - Dahlgren Div 904-234-4184 Panama City, FL DSN:436-4184 Bowers, Clint A Dr Univ of Central...Research 703-696-4318 Arlington, VA DSN:426-4318 Clevenger, J Evans and Sutherland Computer Corp 801-588-1518 Salt Lake City, UT Clingerman, B Space and...Drew W. CAPT Bergondy, M Bilazarian, P Bowers, Clint A Dr Bradley, S Breaux, R Mr Burke, J Burns, Christopher M Mr Burns, J Cannon-Bowers, Janis A Dr

  16. Publishing Your Music Education Research: A Seminar for Future Authors--A Summary of the 2009 Ohio Music Education Association Research Forum Presented By Dr. Wendy Sims

    ERIC Educational Resources Information Center

    Schatt, Matthew D.

    2009-01-01

    The Ohio Music Education Association (OMEA) Research Committee annually hosts a Graduate Research Forum in conjunction with the OMEA's Professional Development Conference. In 2009, the guest speaker was Dr. Wendy Sims, Director of Music Education at the University of Missouri--Columbia and Editor of the Journal of Research in Music Education. An…

  17. REACTOR PHYSICS MODELING OF SPENT RESEARCH REACTOR FUEL FOR TECHNICAL NUCLEAR FORENSICS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nichols, T.; Beals, D.; Sternat, M.

    2011-07-18

    Technical nuclear forensics (TNF) refers to the collection, analysis and evaluation of pre- and post-detonation radiological or nuclear materials, devices, and/or debris. TNF is an integral component, complementing traditional forensics and investigative work, to help enable the attribution of discovered radiological or nuclear material. Research is needed to improve the capabilities of TNF. One research area of interest is determining the isotopic signatures of research reactors. Research reactors are a potential source of both radiological and nuclear material. Research reactors are often the least safeguarded type of reactor; they vary greatly in size, fuel type, enrichment, power, and burn-up. Manymore » research reactors are fueled with highly-enriched uranium (HEU), up to {approx}93% {sup 235}U, which could potentially be used as weapons material. All of them have significant amounts of radiological material with which a radioactive dispersal device (RDD) could be built. Therefore, the ability to attribute if material originated from or was produced in a specific research reactor is an important tool in providing for the security of the United States. Currently there are approximately 237 operating research reactors worldwide, another 12 are in temporary shutdown and 224 research reactors are reported as shut down. Little is currently known about the isotopic signatures of spent research reactor fuel. An effort is underway at Savannah River National Laboratory (SRNL) to analyze spent research reactor fuel to determine these signatures. Computer models, using reactor physics codes, are being compared to the measured analytes in the spent fuel. This allows for improving the reactor physics codes in modeling research reactors for the purpose of nuclear forensics. Currently the Oak Ridge Research reactor (ORR) is being modeled and fuel samples are being analyzed for comparison. Samples of an ORR spent fuel assembly were taken by SRNL for analytical and radiochemical analysis. The fuel assembly was modeled using MONTEBURNS(MCNP5/ ORIGEN2.2) and MCNPX/CINDER90. The results from the models have been compared to each other and to the measured data.« less

  18. PREFACE: National Seminar on Current Trends in Materials Science (CTMS-2011)

    NASA Astrophysics Data System (ADS)

    Jayakrishnan, R.; Vijayakumar, K. P.; Unnikrishnan, N. V.

    2013-05-01

    India is going through an era of many changes in its higher education system. Emphasis is being given to research and development initiatives at Universities and colleges. The teaching community is faced with the challenge of coping with both regular academic activities and research initiatives. The teaching faculties need to keep in step with the momentous research output being generated globally. To mold young talent that will be sought after, teachers need to undertake challenging initiatives. Research in emerging areas like nanotechnology, meta materials, functional materials and structures is being pursued vigorously in Universities and colleges in the state of Kerala. Awareness of the impact of integrating teaching and research in basic science has inspired the teaching faculty. The number of seminars and conferences is not commensurate with the amount of research being conducted in this state. The state lags behind in the number of institutes with state of the art facilities and human resource with cutting edge knowledge. The national seminar on Current Trends in Materials Science (CTMS-2011) is organized by the Department of Physics, Christian College, Chengannur. It is a continuation of the initiatives of the Department to bridge the haitus between teaching and research. Current Trends in Materials Science (CTMS-2007) was successfully conducted with over 80 research paper presentations and participation of delegates from the states of Karnataka, Andhrapradesh, Tamilnadu and Kerala. CTMS-2011 is a sequel envisaged to serve as an effective platform for teachers to interact with eminent scientists and share their knowledge and experience. Papers were invited from the subject area comprising glasses and ceramics, crystal growth, nanotechnology, semiconductors thin films and polymers. We are delighted that after a peer review process of the papers we have selected ten of the best papers presented at the seminar for publication in IOP Conference Series: Materials Science and Engineering. This initiative is in pursuit of the vision of the department to establish itself as a part of the global scientific community. The department is striving to establish itself as a centre of excellence in teaching and research. We sincerely hope that the papers published in this journal will contribute to the advancement of knowledge in the respective fields. We present this volume of papers to the scientific community for their valuable feedback by way of suggestions and collaborative research. Acknowledgment The Department of Physics, Christian College Chengannur acknowledges the efforts of Dr Jacob George who was inspirational in organizing this seminar. His vision and perseverance made it possible for us to organize this event. The seminar was graciously funded by University Grants Commission (UGC), New Delhi, India and Kerala State Council for Science Technology and Environment (KSCSTE), Thiruvananthapuram, Kerala, India. The department wishes to thank both organizations for their support for the event. The management of the college provided great assistance by providing all the infrastructural help required for the event. The department is weighed in gratitude for this gesture and encouragement. Ammini Solar Pvt. Ltd, and Hind High Vacuum Pvt. Ltd, sponsored the best paper award and best poster award respectively. We thank them for this token of their support for the event. The event will be remembered for the participants who arrived from various parts India and the students who made it memorable. The Department acknowledges the efforts of the 2010-2012 and 2009-2011post graduate students who ran the show behind the scenes. National Advisory Board Professor (Dr) K L Chopra (Padamshree) (Former Director, Indian Institute of Technology, Kharagpur) Professor A K Barua (Padamshree) Project Director, MNES/DST project on a-Si Solar cell Professor C Vijayan IIT, Madras Dr M K Jayaraj, Cochin University of Science and technology Dr P Kurian, S B College, Chengannaserry Dr Daisy Philip, Mar Ivanous College,Thiruvananthapuram Local Organizing Committee Patron: Rt Rev Dr Zacharias Mar Theophillus Saffragan Metropolitan Chairman: Dr Jacob George, Principal Vice Chairman: Professor Beena Racheal Thomas, HOD Convenor: Dr Vinoy Thomas Joint Convenor: Dr Sunila Abraham Dr Ligi Cherian, Sri Hysen Thomas, Sri A Abraham, Dr Tiju Joseph Mthew, Smt Agee Susan, Dr Ajit Verghese George, Dr Johnson Baby, Sri Lalu Varghese, Sri Biji Abraham Editorial Committee Editor: Dr R Jayakrishnan Editorial Consultants: Professor K P Vijayakumar, Department of Physics, CUSAT, Cochin, India Professor N V Unnikrishnan, Director, SPAP, MG University, Kottayam, India

  19. Institute for Advanced Materials at University of Louisville

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sunkara, Mahendra; Sumaneskara, Gamini; Starr, Thomas L

    2009-10-29

    In this project, a university-wide, academic center has been established entitled Institute for Advanced Materials and Renewable Energy. In this institute, a comprehensive materials characterization facility has been established by co-locating several existing characterization equipment and acquiring several state of the art instrumentation such as field emission transmission electron microscope, scanning electron microscope, high resolution X-ray diffractometer, Particle Size Distribution/Zeta Potential measurement system, and Ultra-microtome for TEM specimen. In addition, a renewable energy conversion and storage research facility was also established by acquiring instrumentation such as UV-Vis absorption spectroscopy, Atomic Layer Deposition reactor, Solar light simulator, oxygen-free glove box, potentiostat/galvanostatsmore » and other miscellaneous items. The institute is staffed with three full-time staff members (one senior research technologist, a senior PhD level research scientist and a junior research scientist) to enable proper use of the techniques. About thirty faculty, fifty graduate students and several researchers access the facilities on a routine basis. Several industry R&D organizations (SudChemie, Optical Dynamics and Hexion) utilize the facility. The established Institute for Advanced Materials at UofL has three main objectives: (a) enable a focused research effort leading to the rapid discovery of new materials and processes for advancing alternate energy conversion and storage technologies; (b) enable offering of several laboratory courses on advanced materials science and engineering; and (c) develop university-industry partnerships based on the advanced materials research. The Institute's efforts were guided by an advisory board comprising eminent researchers from outside KY. Initial research efforts were focused on the discovery of new materials and processes for solar cells and Li ion battery electrodes. Initial sets of results helped PIs to secure a successful EPSCoR cluster implementation grant by teaming with additional researchers from UK. In addition to research efforts, the project enabled several other outcomes: (a) helped recruit a junior faculty member (Dr. Moises Carreon) and establish a lab focused on meso-porous materials toward separation and catalysis; (b) enabled offering of three new, graduate level courses (Materials characterization using spectroscopy and microscopy; Electron and x-ray diffraction; and renewable energy systems); and (c) mentoring of a junior faculty members (Dr. Gerold Willing).« less

  20. Then & Now: Research Pays Off for All Americans / Dr. Virginia Apgar: Keeping Score at Baby's First Cry | NIH ...

    MedlinePlus

    ... Elizabeth Wilcox, Archives & Special Collections, Columbia University Health Sciences Library Dr. Apgar's advice to mothers is summarized in ... more about Dr. Apgar through the Profiles in Science program of the National Library of Medicine and through the NLM exhibit Changing ...

  1. Mobility Research and Development (Briefing charts)

    DTIC Science & Technology

    2016-03-17

    Mobility Research & Development Dr. Paramsothy Jayakumar, STE, Analytics Tank Automotive Research, Development and Engineering Center Research...Mobility Model (NRMM) • Dr. M. G. Bekker of TARDEC is the “Father of Terrain-Vehicle Systems ” • NRMM was developed in 1960-70 by TARDEC and ERDC...Blocks: Scaled Experiments Particle Image Velocimetry Pressure – Sinkage Test Direct Shear Test Simulations Single Wheel Test Plate width = 50 mm

  2. Manuel Stein's Five Decades of Structural Mechanics Contributions (1944-1988)

    NASA Technical Reports Server (NTRS)

    Mikulas, Martin M.; Card, Michael F.; Peterson, Jim P.; Starnes, James H., Jr.

    1998-01-01

    Manuel Stein went to work for NACA (National Advisory Committee for Aeronautics) in 1944 and left in 1988. His research contributions spanned five decades of extremely defining times for the aerospace industry. Problems arising from the analysis and design of efficient thin plate and shell aerospace structures have stimulated research over the past half century. The primary structural technology drivers during Dr. Stein's career included 1940's aluminum aircraft, 1950's jet aircraft, 1960's launch vehicles and advanced spacecraft, 1970's reusable launch vehicles and commercial aircraft, and 1980's composite aircraft. Dr. Stein's research was driven by these areas and he made lasting contributions for each. Dr. Stein's research can be characterized by a judicious mixture of physical insight into the problem, understanding of the basic mechanisms, mathematical modeling of the observed phenomena, and extraordinary analytical and numerical solution methodologies of the resulting mathematical models. This paper summarizes Dr. Stein's life and his contributions to the technical community.

  3. Operational Intelligence and Operational Design: Thinking about Operational Art

    DTIC Science & Technology

    2011-06-01

    undersigned certify that this thesis meets masters-level standards of research, argumentation, and expression. DR. HAROLD R . WINTON (Date) DR...Studies (SAASS) to study and think about matters important to our national security. I will be forever grateful to Dr. Harold R . Winton, my thesis...thankful for the assistance of Mrs. Sandhya Malladi and Dr. Mary Ruwell. To the faculty and staff of SAASS, thank you for your commitment to our

  4. Effects of Temperature and Environment on Creep Behavior of an Oxide-Oxide Ceramic Matrix Composite

    DTIC Science & Technology

    2007-03-01

    Zelina, Dr. Ruth Sikorski, and Dr. Ron Kerans, whose sponsorship made my research possible; Dr. Robert Canfield and Dr. Som Soni, for their membership...on my thesis committee and discerning comments; Lt Joseph Broeckert, Lt Christina Falcone, Capt Christine Ladrido, and LT Robert Salvia, whose...Society for Testing and Materials (1997). 54. Raymer , D.P. Aircraft Design: A Conceptual Approach, 3rd Edition. Reston, VA: American Institute of

  5. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goyal, Amit

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grainmore » supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy 100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.« less

  6. Genetic engineering of a mouse: Dr. Frank Ruddle and somatic cell genetics.

    PubMed

    Jones, Dennis

    2011-06-01

    Genetic engineering is the process of modifying an organism's genetic composition by adding foreign genes to produce desired traits or evaluate function. Dr. Jon W. Gordon and Sterling Professor Emeritus at Yale Dr. Frank H. Ruddle were pioneers in mammalian gene transfer research. Their research resulted in production of the first transgenic animals, which contained foreign DNA that was passed on to offspring. Transgenic mice have revolutionized biology, medicine, and biotechnology in the 21st century. In brief, this review revisits their creation of transgenic mice and discusses a few evolving applications of their transgenic technology used in biomedical research.

  7. Research Area 3: Mathematics (3.1 Modeling of Complex Systems)

    DTIC Science & Technology

    2017-10-31

    RESEARCH AREA 3: MATHEMATICS (3.1 Modeling of Complex Systems). Proposal should be directed to Dr. John Lavery The views, opinions and/or findings...so designated by other documentation. 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS (ES) U.S. Army Research Office P.O. Box 12211 Research ...Title: RESEARCH AREA 3: MATHEMATICS (3.1 Modeling of Complex Systems). Proposal should be directed to Dr. John Lavery Report Term: 0-Other Email

  8. Eastern Europe Research Reactor Initiative nuclear education and training courses - Current activities and future challenges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snoj, L.; Sklenka, L.; Rataj, J.

    2012-07-01

    The Eastern Europe Research Reactor Initiative was established in January 2008 to enhance cooperation between the Research Reactors in Eastern Europe. It covers three areas of research reactor utilisation: irradiation of materials and fuel, radioisotope production, neutron beam experiments, education and training. In the field of education and training an EERRI training course was developed. The training programme has been elaborated with the purpose to assist IAEA Member States, which consider building a research reactor (RR) as a first step to develop nuclear competence and infrastructure in the Country. The major strength of the reactor is utilisation of three differentmore » research reactors and a lot of practical exercises. Due to high level of adaptability, the course can be tailored to specific needs of institutions with limited or no access to research reactors. (authors)« less

  9. An interview with Peter H. Buschang.

    PubMed

    Buschang, Peter H; dos Santos-Pinto, Ary; Araújo, Eustáquio; Ribeiro, Gerson Luiz Ulema; Jacob, Helder Baldi; Gandini Júnior, Luiz Gonzaga

    2014-01-01

    Dr. Peter Buschang is regent professor and director of orthodontic research. He has been at Texas A&M University Baylor College of Dentistry since 1988. Dr. Buschang received his PhD in 1980 from the University of Texas at Austin; he spent 3 years as a NIDR postdoctoral fellow at the University of Connecticut, and five years as a FRSQ scholar at the University of Montreal. Every year, Dr. Buschang teaches in 16 different courses, 7 of which he directs. In addition to more than 100 lecture hours per year, he spends hundreds of hours mentoring students. For his teaching efforts, Dr. Buschang was awarded the Robert E. Gaylord Award of Excellence in Orthodontic education in 1992, 1998, 2004, and 2010. He also gives 1-2 day evidence-based CE courses throughout the world. The residents he has taught recently honored him by pledging to fund the Peter H. Buschang Endowed Professorship of Orthodontics. His research interests pertain to craniofacial growth and assessment of treatment effects. Dr. Buschang has been funded regularly over the years by the Medical Research Council of Canada, Fonds de le Recherche en Santé du Québec, the NIH, and the American Association of Orthodontics Foundation. He has mentored over 140 Master's and PhD students, and 49 dental students. Dr. Buschang has published over 250 peer-reviewed articles, 15 book chapters and 198 abstracts. He has given over 150 invited talks and lectures in 14 different countries. For his work with the American Board of Orthodontics, Dr. Buschang was awarded the Earl E. and Wilma S. Shepard Award. Dr. Buschang is the only non-orthodontist ever to have been made an honorary member of both the American Association of Orthodontics (2005) and the Edward H. Angle Society of Orthodontics (2009), the two most prestigious orthodontic groups.

  10. PREFACE: The 3rd ISESCO International Workshop and Conference On Nanotechnology 2012 (IWCN2012)

    NASA Astrophysics Data System (ADS)

    Umar, Akrajas Ali; Yahaya, Muhammad; Mat Salleh, Muhamad

    2013-04-01

    The ISESCO Conference on Nanomaterials and Applications (IWCN2012) is one of a series of nanotechnology seminars organized by ISESCO, Malaysian Solid State Science and Technology Society (MASS), the Universiti Kebangsaan Malaysia. IWCN2012 is the third seminar, following IWCN2007 and IWCN2010, held in the Universiti Kebangsaaan Malaysia, Bangi Malaysia from 5-7 December 2012. The conference was attended by more than 250 participants from 15 countries, including 150 students. The conference and workshop provided a forum for researchers and students, policymakers and other professionals especially from the ISESCO Member States to exchange information, enhance understanding and more importantly to engage in the development of new nanoscience and nanotechnology research in multidisciplinary areas in physics, chemistry and biology. Together with the conference, the third Meeting of the ISESCO Expert Panel on Nanotechnology was held to chart the future activities in Nanoscience and Nanotechnology in ISESCO member countries. The objective of the conference is to communicate and discuss recent progress in nanoscience and nanotechnology research and its potential applications in future economic growth. The main focus for the present activity is on energy and environment. The conference received 105 papers in total and 50 of them were selected to be considered for publication in Journal of Physics: Conference Series. However, finally, after undergoing vigorous and thorough revisions by respected editors and reviewers in the fields, 29 papers were accepted. This volume covers the follwing topics: Nanomaterials Synthesis and Characterization Nanomaterials for Energy and Catalysis Nanoelectronics, Sensors and MEMS Devices Nanophotonics We are indebted to all the keynote speakers, invited speakers, participant and authors for their contribution to this event. Their contribution has led to the success of this conference. We are also very grateful for the time, effort and unwavering support dedicated by all the referees. Their tireless work has helped guarantee the high scientific level of this series. Many thanks are also addressed to the ISESCO, COMSATS, MASS, UKM and FST for their financial support. Logistics support provided by IMEN and MNA is also much appreciated. We realized that this volume would never have materialized without the hard work of Ms Siti Khatijah Md Saad who helped the editorial secretariat in many ways communicating with the authors and reviewers and checking and typesetting the papers in the final stage. Finally, great appreciation is addressed to all who have worked hard and given support ensuring that the conference was a success. Editors Associate Professor Dr Akrajas Ali Umar Professor Dr Muhamad Mat Salleh Professor Dato' Dr Muhammad Yahaya IWCN 2012 Organizing Committee International Advisory Board Professor Dato' Dr Muhammad Yahaya (UKM, Malaysia) Dr Faiq Bilal (ISESCO, Morocco) Professor Dr Michael Graetzel (Switzerland) Professor Dr Muhamad Rasat (Malaysia) Prof Dr Masbah R T Siregar (Indonesia) Associate Professor Dr Munetaka Oyama (Japan) Professor Dr Ismat Shah (USA) Professor Dr Muhamad Mat Salleh (Malaysia) Chairman Associate Professor Dr Mohammad Kassim Co-Chairman Dr Mohammad Hafizuddin Haji Jumali Secretary Dr Lorna Jeffry Minggu Treasurer Dr Sharina Abu Hanifah Committee Members Associate Professor Dr Mohd Azmi Abd Hamid Associate Professor Dr Akrajas Ali Umar Dr Zahari Ibarahim Dr Rozidawati Awang Dr Farah Hannan Anuar Secretariat Dr Khuzaimah Mohd Firdauz Ismail Izura Izzuddin Nor Huwaida Janil Jamil Siti Khatijah Md Saad Noor Razinah Rahmat Mark Lee Wun Fui Ng Kim Hang Lee Thian Khoon Law Kung Pui Choong Yan Yi

  11. Utilizing Biomarker Signature Pairs To Develop Gene Therapeutic Viral Delivery Platforms For Treating Prostate Cancer

    Cancer.gov

    Dr. Tamaro Hudson is currently an Assistant Professor at Howard University in the Department of Pharmacology and holds an appointment as a Health Research Specialist at the Washington VA Medical Center. Dr. Hudson received his Bachelor of Science from Iowa State University in Biology in 1994 and went on to receive a Master of Science in Preventive Medicine from Ohio State University in 2007. Afterwards, he received a Ph.D. from Ohio State University in 2002 where he focused on evaluating the functional differences among isothiocyanates in the rat esophageal tumor model. Following his Ph.D., Dr. Hudson was selected to complete a prestigious Cancer Prevention Fellowship Program at the National Institute of Health, National Cancer Institute, where he focused on utilizing in vitro and in vivo cancer models to assess the biological activity of bioactive compounds on prostate cancer molecular pathways. Concurrently, he completed a Master of Public Health degree from George Washington University in 2003 where he focused on assessing the degree of agreement between a food frequency questionnaire and a 4-day food record as it related to dietary fiber intake. Upon completion of his MPH and Fellowship, he was recruited by Howard University Cancer Center in 2007 as an Assistant Professor. Since joining the Howard faculty, Dr. Hudson has integrated his research focus by identifying novel signature biomarkers – that could have a significant impact on both the diagnosis and targeted treatment of prostate cancer – with the evaluation of new chemopreventive strategies, which have been evaluated in Phase I and Phase II clinical trials. Dr. Hudson received the first five-year VA-HBCU Research, Scientist, and Training grant that focuses on developing a biomarker-based risk prediction model for prostate cancer. Dr. Hudson serves on several Howard University committees and has many peer-reviewed publications. Dr. Hudson's research interests continue to expand as he tries to build collaborations across broad disciplines to make an impact in translational research.  

  12. Modeling Incorrect Responses to Multiple-Choice Items with Multilinear Formula Score Theory.

    DTIC Science & Technology

    1987-08-01

    Eisenhower Avenue University of Leyden Alexandria, VA 22333 Education Research Center Boerhaavelaan 2 Dr. John M. Eddins 2334 EN Leyden University of...22302-0268 Dr. William Montague NPRDC Code 13 Dr. William L. Maloy San Diego, CA 92152-6800 Chief of Naval Education and Training Ms. Kathleen Moreno

  13. When Diversity Training Isn’t Enough: The Case for Inclusive Leadership

    DTIC Science & Technology

    2013-08-06

    professionals with disabilities . Professional Psychology: Research and Practice, 40, 201–205. Day, R., & Allen, T. D. (2004). The relationship between...DIRECTORATE OF RESEARCH DEVELOPMENT AND STRATEGIC INITIATIVES Dr. Richard Oliver Hope Human Relations Research Center Directed by Dr. Daniel P. McDonald...believes diversity leads to increased conflict and decreased cohesion. Indeed, research over the past several decades has often been contradictory. On

  14. Modeling Item Responses When Different Subjects Employ Different Solution Strategies.

    DTIC Science & Technology

    1987-10-01

    Crombag Dr. Stephen Dunbar University of Leyden Lindquist Center Education Research l-enter for Measurement Boerhaavelaan 2 University of Iowa 2334 EN... Leyden Iowa City, IA 52242 The NEFHlPLANDS Dr. James A. F.arles Mr. Iimothy Davey Air Force Human Resources Lab iJniversity of Illinois Brooks AFB, TX...Education and Training Dr. William Montague Naval Air Station NPRDC Code 13 Pensacola, fL 32508 San Diego, CA 92152-6800 Dr. Gary Marco Ms. Kathleen Moreno

  15. United States Air Force Summer Faculty Research Program. 1985 Technical Report. Volume 2.

    DTIC Science & Technology

    1985-12-01

    Voluntary Hand Grip Torque for Dr. Samuel Adams Circular Electrical Connectors 3 Properties and Processing of a Dr. Vernon R. Allen Perfluorinated ...Neutral Particle Beam at Low Energies in the Mark I Aerospace Chamber 126 Preparation of Non-Flammable Model Dr. Terrill D. Smith Compounds 127 Studies on...Synthesis of Azo Compounds F xi 140 A Comparison of Measured and Calculated Dr. Larry Vardiman Attenuation of 28 GHZ Beacon Signals in Three California

  16. Tapered Wiggler Analysis of High Gain Free Electron Laser Oscillators.

    DTIC Science & Technology

    1987-12-12

    Vladislav Bevc Livermore, CA 94550 Synergy Research Institute P.O. Box 561 Dr. H. Brandt San Ramon , CA 94583 Department of the Army Harry Diamond...800 N. Quincy Street 3011 Malibu Canyon Road Arlington, VA 22217 Malibu, CA 90265 Dr. B. Robinson Dr. Antonio Sanchez Boeing Aerospace Company...Walsh, Jr. Dr. R. Whitefield Bell Laboratories 15260 Dickens Ave. 600 Mountain Avenue San Jose , CA 95124 Room I-D 332 Murray Hill, NJ 07974 Ms

  17. United States Air Force Summer Faculty Research Program 1989. Program Technical Report. Volume 2

    DTIC Science & Technology

    1989-12-01

    of an Osmotically Dr. Juin Yu Driven Thermal Transfer Cycle 114 The Influence of Viscoelastically Dr. Lawrence Zavodney Damped Members on the Dynamic...Hormones Effect Upon Dr. Rex Moyer Chlamydomonas Phototaxis 166 Influence of Radio Frequency Dr. Raymond Quock Radiation on Psychotropic Drug Effects 167...systems do not cover. Therefore, the use of SHG for creating coherent light at twice the frequency of an- other laser is one way to extend the range

  18. USAF/SCEEE Summer Faculty Research Program (1982). Research Reports. Volume 2.

    DTIC Science & Technology

    1982-10-01

    Engineering (802) 658-3330 Assigned: RADC/Griffiss Dr. Milton J. Alexander Degree: D.B.A., Management , 1968 Professor Specialty: Management ...Information Auburn University Systems, Operational Management Department Research Auburn, AL 36830 Assigned: LMC (205) 826-4730 Dr. Gary L. Allen Degree: Ph.D...Ph.D., Industrial Professor Engineering, 1951 Oklahoma State University Specialty: Project Management , Industrial Engineering & Management Dept

  19. Disparities in Intratumoral Steroidogenesis

    DTIC Science & Technology

    2017-12-01

    was a Health Disparity Prostate Cancer Research Award originally to Dr. Keith Solomon at Boston Children’s Hospital. In 2015, Dr. Solomon lost the rest... Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for Public Release; Distribution Unlimited The...AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 11. SPONSOR

  20. Advanced Test Reactor National Scientific User Facility (ATR NSUF) Monthly Report November 2014

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soelberg, Renae

    2014-11-01

    Advanced Test Reactor National Scientific User Facility (ATR NSUF) Monthly Report November 2014 Highlights Rory Kennedy and Sarah Robertson attended the American Nuclear Society Winter Meeting and Nuclear Technology Expo in Anaheim, California, Nov. 10-13. ATR NSUF exhibited at the technology expo where hundreds of meeting participants had an opportunity to learn more about ATR NSUF. Dr. Kennedy briefed the Nuclear Engineering Department Heads Organization (NEDHO) on the workings of the ATR NSUF. • Rory Kennedy, James Cole and Dan Ogden participated in a reactor instrumentation discussion with Jean-Francois Villard and Christopher Destouches of CEA and several members of themore » INL staff. • ATR NSUF received approval from the NE-20 office to start planning the annual Users Meeting. The meeting will be held at INL, June 22-25. • Mike Worley, director of the Office of Innovative Nuclear Research (NE-42), visited INL Nov. 4-5. Milestones Completed • Recommendations for the Summer Rapid Turnaround Experiment awards were submitted to DOE-HQ Nov. 12 (Level 2 milestone due Nov. 30). Major Accomplishments/Activities • The University of California, Santa Barbara 2 experiment was unloaded from the GE-2000 at HFEF. The experiment specimen packs will be removed and shipped to ORNL for PIE. • The Terrani experiment, one of three FY 2014 new awards, was completed utilizing the Advanced Photon Source MRCAT beamline. The experiment investigated the chemical state of Ag and Pd in SiC shell of irradiated TRISO particles via X-ray Absorption Fine Structure (XAFS) spectroscopy. Upcoming Meetings/Events • The ATR NSUF program review meeting will be held Dec. 9-10 at L’Enfant Plaza. In addition to NSUF staff and users, NE-4, NE-5 and NE-7 representatives will attend the meeting. Awarded Research Projects Boise State University Rapid Turnaround Experiments (14-485 and 14-486) Nanoindentation and TEM work on the T91, HT9, HCM12A and 9Cr ODS specimens has been completed at CAES by Boise State PI Janelle Wharry and Cory Dolph. PI Corey Dolph returned in early November to complete their research by performing nanoindentation on unirradiated specimens that will be used as a baseline for their research.« less

  1. Proceedings of the seminar on Leak-Before-Break: Progress in regulatory policies and supporting research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kashima, K.; Wilkowski, G.M.

    1988-03-01

    The third in a series of international Leak-Before-Break (LBB) Seminars supported in part by the US Nuclear Regulatory Commission was held at TEPCO Hall in the Tokyo Electric Power Company's (TEPCO) Electric Power Museum on May 14 and 15, 1987. The seminar updated the international policies and supporting research on LBB. Attendees included representatives from regulatory agencies, electric utility representatives, fabricators of nuclear power plants, research organizations, and university professors. Regulatory policy was the subject of presentations by Mr. G. Arlotto (US NRC, USA), Dr. H. Schultz (GRS, W. Germany), Dr. P. Milella (ENEA-DISP, Italy), Dr. C. Faidy, P. Jamet,more » and S. Bhandari (EDF/Septen, CEA/CEN, and Framatome, France), and Mr. T. Fukuzawa (MITI, Japan). Dr. F. Nilsson presented revised nondestructive inspection requirements relative to LBB in Sweden. In addition, several papers on the supporting research programs discussed regulatory policy. Questions following the presentations of the papers focused on the impact of various LBB policies or the impact of research findings. Supporting research programs were reviewed on the first and second day by several participants from the US, Japan, Germany, Canada, Italy, Sweden, England, and France.« less

  2. Energetic Azido Compounds

    DTIC Science & Technology

    1980-03-28

    Dr. F. Roberto Lt. S. Clift Naval Weapons Center 3 Mr. ;. Geisler Chi•a Lakre, CA 93555 4a Attn: Dr. A. Amsrer, Code 385 U.S. Army Research Office I...Research Naval: Weapons Center 1 Directorate of Chemical Sciences China Lake, CA 93555 Bolling Air Force Base Attn: Mr. H. Richter, Code 3858

  3. 78 FR 58575 - Review of Experiments for Research Reactors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-24

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0219] Review of Experiments for Research Reactors AGENCY... Commission (NRC) is withdrawing Regulatory Guide (RG) 2.4, ``Review of Experiments for Research Reactors... withdrawing RG 2.4, ``Review of Experiments for Research Reactors,'' (ADAMS Accession No. ML003740131) because...

  4. Human radiation studies: Remembering the early years. Oral history of radiologist Earl R. Miller, M.D., August 9 and 17, 1994

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-06-01

    Dr. Earl R. Miller was interviewed by representatives of US DOE Office of Human Radiation Research (OHRE). The interview covers Dr. Miller`s involvement with the Manhattan Engineer District, with total body irradiation, and heavy-ion therapy. Dr. Miller`s remembrances include wartime work on radiation exposure, Joe Hamilton, Neutron Therapy research, means of obtaining isotopes, consent forms, infinite laminograms, invention of a baby holder to alleviate exposure of radiological technicians in diagnostic procedures involving infants, and several personages.

  5. Summary of ORSphere critical and reactor physics measurements

    NASA Astrophysics Data System (ADS)

    Marshall, Margaret A.; Bess, John D.

    2017-09-01

    In the early 1970s Dr. John T. Mihalczo (team leader), J.J. Lynn, and J.R. Taylor performed experiments at the Oak Ridge Critical Experiments Facility (ORCEF) with highly enriched uranium (HEU) metal (called Oak Ridge Alloy or ORALLOY) to recreate GODIVA I results with greater accuracy than those performed at Los Alamos National Laboratory in the 1950s. The purpose of the Oak Ridge ORALLOY Sphere (ORSphere) experiments was to estimate the unreflected and unmoderated critical mass of an idealized sphere of uranium metal corrected to a density, purity, and enrichment such that it could be compared with the GODIVA I experiments. This critical configuration has been evaluated. Preliminary results were presented at ND2013. Since then, the evaluation was finalized and judged to be an acceptable benchmark experiment for the International Criticality Safety Benchmark Experiment Project (ICSBEP). Additionally, reactor physics measurements were performed to determine surface button worths, central void worth, delayed neutron fraction, prompt neutron decay constant, fission density and neutron importance. These measurements have been evaluated and found to be acceptable experiments and are discussed in full detail in the International Handbook of Evaluated Reactor Physics Benchmark Experiments. The purpose of this paper is to summarize all the evaluated critical and reactor physics measurements evaluations.

  6. Nuclear Reactors. Revised.

    ERIC Educational Resources Information Center

    Hogerton, John F.

    This publication is one of a series of information booklets for the general public published by the United States Atomic Energy Commission. Among the topics discussed are: How Reactors Work; Reactor Design; Research, Teaching, and Materials Testing; Reactors (Research, Teaching and Materials); Production Reactors; Reactors for Electric Power…

  7. Research Program of a Super Fast Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Oka, Yoshiaki; Ishiwatari, Yuki; Liu, Jie

    2006-07-01

    Research program of a supercritical-pressure light water cooled fast reactor (Super Fast Reactor) is funded by MEXT (Ministry of Education, Culture, Sports, Science and Technology) in December 2005 as one of the research programs of Japanese NERI (Nuclear Energy Research Initiative). It consists of three programs. (1) development of Super Fast Reactor concept; (2) thermal-hydraulic experiments; (3) material developments. The purpose of the concept development is to pursue the advantage of high power density of fast reactor over thermal reactors to achieve economic competitiveness of fast reactor for its deployment without waiting for exhausting uranium resources. Design goal is notmore » breeding, but maximizing reactor power by using plutonium from spent LWR fuel. MOX will be the fuel of the Super Fast Reactor. Thermal-hydraulic experiments will be conducted with HCFC22 (Hydro chlorofluorocarbons) heat transfer loop of Kyushu University and supercritical water loop at JAEA. Heat transfer data including effect of grid spacers will be taken. The critical flow and condensation of supercritical fluid will be studied. The materials research includes the development and testing of austenitic stainless steel cladding from the experience of PNC1520 for LMFBR. Material for thermal insulation will be tested. SCWR (Supercritical-Water Cooled Reactor) of GIF (Generation-4 International Forum) includes both thermal and fast reactors. The research of the Super Fast Reactor will enhance SCWR research and the data base. The research period will be until March 2010. (authors)« less

  8. Genetics in Diabetic Retinopathy: Current Concepts and New Insights

    PubMed Central

    Simó-Servat, Olga; Hernández, Cristina; Simó, Rafael

    2013-01-01

    There is emerging evidence which indicates the essential role of genetic factors in the development of diabetic retinopathy (DR). In this regard it should be highlighted that genetic factors account for 25-50% of the risk of developing DR. Therefore, the use of genetic analysis to identify those diabetic patients most prone to developing DR might be useful in designing a more individualized treatment. In this regard, there are three main research strategies: candidate gene studies, linkage studies and Genome-Wide Association Studies (GWAS). In the candidate gene approach, several genes encoding proteins closely related to DR development have been analyzed. The linkage studies analyze shared alleles among family members with DR under the assumption that these predispose to a more aggressive development of DR. Finally, Genome-Wide Association Studies (GWAS) are a new tool involving a massive evaluation of single nucleotide polymorphisms (SNP) in large samples. In this review the available information using these three methodologies is critically analyzed. A genetic approach in order to identify new candidates in the pathogenesis of DR would permit us to design more targeted therapeutic strategies in order to decrease this devastating complication of diabetes. Basic researchers, ophthalmologists, diabetologists and geneticists should work together in order to gain new insights into this issue. PMID:24403848

  9. [Pharmacologists in the camps in the Third Reich--part second].

    PubMed

    Labuzek, Krzysztof; Prusek, Katarzyna; Gonciarz, Maciej; Okopień, Boguslaw

    2013-10-01

    SS Hygiene Institute provided adequate funding for research on the treatment of mycobacterial infections, and two scientists who became famous in the subject were Dr. Waldemar Hoven (KL Buchenwald) and Dr. Kurt Heissmeyer (KL Neuengamme). They conducted researches not only on adult prisoners, but also on the Jewish children. Studies of tuberculosis were also conducted under the auspices of the German Medical Association by Dr. Rudolf Brachtel. In turn, Dr. Klaus Schilling dealt with the treatment and immunoprophylaxis of malaria. He tested such substances, as pyramidon, aspirin, quinine and atebrin on more than 1200 prisoners. These sulfonamide-derived drugs, were also studied by prof. Karl Gebhardt and Dr. Fritz Fischer. They assessed the efficacy of these drugs in the treatment of "dirty" wounds incurred by German soldiers. Dr. Heinrich Schutz, Karl Babor and Waldemar Wolter they were enthusiasts in so-called biochemical therapy, based on the use of substances of natural origin, such as salt. After termination of War, during the Nuremberg Trials, many of them evaded responsibility, they were running medical practices, some were publishing. However, despite those facts, trials of Nazi war criminals were not result less, they opened world's eyes for the necessity of clarifying rudiments of human subject research, they gave foundations to define records like The Convention for the Protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine or Good Clinical Practice.

  10. Special issue dedicated in memory of Dr. Edward H. Ahrens, Jr.

    PubMed

    Ahrens, Edward H

    2002-01-01

    This special issue of the "Cardiovascular Drug Reviews" is dedicated in memory of Dr. Edward H. Ahrens, Jr., who died on Dec. 9th, 2000 at the Princeton Medical Center in New Jersey at the age of 85. Dr. Ahrens was the Director of the Lipid Metabolism Laboratory at the Rockefeller University. Dr. Alexander Scriabine conceived the idea for the issue at the special memorial symposium held at the Rockefeller University on Feb. 05, 2002 under the auspices of The New York Lipid and Vascular Biology Research Club. Dr. Ahrens was the first president of the club. He started this club with Drs. Howard Eder and DeWitt Goodman. Dr. Eder thought that it would be a fitting attribute to honor one of the founding fathers of the club by hosting a memorial symposium. I, as the President of the club for that academic year, had no hesitation in accepting the proposal. This year will be the 40th anniversary of the club and its continued success provides a glimpse of the fine legacy left behind by Dr. Ahrens. Dr. Ahrens also played a pivotal role in the establishment of the Journal of Lipid Research. This is the 43rd year of the journal and in this commemorative issue we are reproducing a review he wrote for the 25th anniversary of the journal. I was never personally acquainted with Dr. Ahrens. However, I am honored that I got this opportunity to pay tribute to a great scientist whose work has contributed immensely to the progress of lipid research. He was a person who touched many lives and still continues to do so. My involvement in the remembrance of Dr. Ahrens shows that science not only impacts your contemporaries but also generations that follow you. Scientific research is a journey where you can leave your trails behind and be remembered for your work long after your departure from this world. Dr. Ahrens contributed immensely to the understanding of cholesterol metabolism. In the early stages of his career he showed that phospholipids solubilize fat in the blood. Now we know that a monolayer of phospholipids surrounds the neutral lipid core of cholesterol esters and triglycerides in lipoproteins. This monolayer contains proteins, called apolipoproteins, which play a major role in lipoprotein catabolism. Lipoproteins are the major vehicles that transport triglycerides and cholesterol in the plasma. He also described a new form of primary biliary cirrhosis characterized by the presence of xanthomas and hyperlipidemia with normal translucent plasma. Subsequently, his group at the Rockefeller Institute developed methods for the separation of lipids using silicic acid columns, isolated highly unsaturated long chain fish oil fatty acids using gas-liquid chromatography, standardized techniques to study sterol metabolism, and introduced the concept of using beta-sitosterolemia as an internal marker for cholesterol balance studies. These studies revealed that individuals show a reproducible response to a given regimen when studied over time. In contrast, different individuals may respond differently to the same regimen. Throughout his career, Dr. Ahrens championed metabolic studies in humans and has passionately argued for the continuation of such investigations. Dr. Ahrens also left behind trails of "graduates." Several of them are currently prominent scientists in their own fields. In this issue, Drs. Davignon and Samuel share their feelings for him in the form of "Remembrance" and "Curriculum Vitae." Dr. Salen has submitted a preview of his research progress towards the understanding of sitosterolemia. Dr. Hudgins and associates have acknowledged the efforts of Dr. Ahrens in binding LDL apheresis technique to the United States of America and have previewed the use of this procedure in the treatment of hypercholesterolemic patients. The contributions of these and other graduates will keep his legacy alive for a long time to come. We are truly grateful for this opportunity to pay homage to such a distinguished scientist.

  11. A Nonparametric Multidimensional IRT Approach with Applications to Ability Estimation and Test Bias.

    DTIC Science & Technology

    1988-04-01

    VA 22314 800 N. Quincy Street Attn: TC Arlington, VA 22217-5000 (12 Copies) Dr. Hans Crombag Dr. Stephen Dunbar University of Leyden Lindquist...CenterEducation Research Center for Measurement Boerhaavelaan 2 University of Iowa 2334 EN Leyden Iowa City, IA 52242 The NETHERLANDS Dr. James A. Earles Mr...William Montague Naval Air Station NPRDC Code 13 Pensacola, FL 32508 San Diego, CA 92152-6800 Dr. Gary Marco Ms. Kathleen Moreno Stop 31-E Navy Personnel R

  12. Physical Properties of Polymers (Ultrastructure Processing of Polymers)

    DTIC Science & Technology

    1982-09-30

    vinyl benzene Network-Diluent Systems". 17. J . Appl. Polym. Sci. 28, 219-224 (1983) (with R. Vukovic and W.J. MacKnight) "Compatibility of Some...Temperature of Polymer Networks by Dil uents". 23. J . Appl. Polym. Sci. 28, 1379-1389 (1983) (with R. Vukovic , V. Kuresevic, N. Segudovic, and W.J...AFOSR 80-0101 IV. DATES: 1 January 1980 - 30 September 1982 V. SENIOR RESEARCH PERSONNEL*: Dr. C. Crosby Dr. G. ten Brinke Dr. T. Ellis Dr. R. Vukovic

  13. Ultrastructure Processing and Characterization of Polymers

    DTIC Science & Technology

    1988-01-01

    Eur. Polym. J . 24, 123-127 (1988) (with R. Vukovic , G. Bogdanic, V. Kuresevic, and W.J. MacKnight) "Miscibility and Phase Behavior in Poly (2,6...Month, Day) |I5 fAGE U d FINAL FROM TO j -"_ 16. SUPPLEMENTARY NOTATION 17. COSATI CODES 18. SUBJECT TERMS (Continue on reverse if necessary and...Lee Dr. J . Obrzut Dr. D. Rice Dr. J . Schlenoff Dr. J . Shim V. JUNIOR RESEARCH PERSONNEL: M. Bishop R. Gregorius M. Lux J . Machado M. Masse R

  14. The SME (Structure-Mapping Engine) User’s Manual (SME Version 2E)

    DTIC Science & Technology

    1988-12-30

    It is prior to this step that one might want to think about wether to modify any system parameters (e.g., print the match hypotheses, print only the...Wshington, DC 20390 Department of Psychology Carnegie-Mellon University Dr. Judith Orsanu Schenley Park Dr. Harold P. O’Neil, Jr. Basic Research Office...Pinker Baltimore, MD 21201 Department of Psychology ElO-018 Dr. Judith W. Segal MIT Dr. J. Wesley Regian OERI Cambridge, MA 02139 AFHRL/IDI 556 New

  15. BUILDING THE FORCE OF THE FUTURE: A NEW CALL TO ATTRACT, HIRE AND RETAIN THE BEST AND BRIGHTEST TO AIR FORCE CIVIL SERVICE

    DTIC Science & Technology

    2015-10-25

    Graduation Requirements Advisors: Dr . Gregory F. Intoccia and Dr . Patricia Lessane Maxwell Air Force Base, Alabama 25 October 2015 DISTRIBUTION A...support while I was diverting much of my free time and attention to this graduate program. I appreciate my research advisors Dr . Greg Intoccia and Dr ...underutilized USAJOBS, the federal government job search engine, as compare to LinkedIn , Career Builders and Monster. Only 8.8 percent of the

  16. A Non-Linear Finite Element Model for the Determination of Elastic and Thermal Properties of Nanocomposites

    DTIC Science & Technology

    2009-04-01

    individuals who helped me in many ways throughout my research and thesis writing process. First and foremost, my sincere thanks go to my advisor, Dr... go to Professor John Akin who helped me in the technical areas of Finite Element programming. Thank you for your time and efforts beyond the...classroom. Thank you to Dr. Enrique Barrera and Dr. Jun Lou for serving on my thesis committee. Many thanks go to Dr. Jan Hewitt as well for volunteering

  17. Connecting High-Impact Practices, Scholarly and Creative Teaching, and Faculty Development: An Interview with Dr. Aaron Thompson

    ERIC Educational Resources Information Center

    Morin, Courtnie; Stanley, Candace

    2017-01-01

    Building upon Kuh's (2008) research on high-impact educational practices, the authors interviewed Dr. Aaron Thompson to discuss effective implementation of these teaching and learning initiatives and the advancement of faculty development programming to support them. Dr. Thompson is the Interim President of Kentucky State University and Council on…

  18. Computer Simulation of the Effect of Pretreatment with Reversible Acetylcholinesterase Inhibitors on the Protection Against Soman Poisoning

    DTIC Science & Technology

    1993-12-01

    dr. U.A. Th. Brinkmnan 31* Directeur van het Medisch Biologisch Laboratorium TNO Prof. dr. W.R.F. Notten 32 PML-TNO, Directeur; daarna reserve 33 PML...Generaal Personeel Ministerie van Defensie 8* Adviseur van het Prins Maurits Laboratorium TNO Chemnische Research Prof. dr. G. Dijkstra 9* lid van de

  19. Back-of-the-Envelope Problems.

    DTIC Science & Technology

    1987-07-01

    S D This researh was ’rdd by the Office of Naval Research with Ccntract N00014-5-K-0095. i roiect NR e67-544. Approved for public release...NY 10027 Dr Gary Aston-Jones Dr. R. Darrell Bock Dr. Patricia A. Butler Deot. of Biology , N.Y.U. University of Chicago, NORC OERI 10C9 Main Bldg

  20. Identification of Components or Fractions Associated with Adverse Changes in Freeze Dried Chicken and Pork during Storage

    DTIC Science & Technology

    1978-06-01

    Products Util- ization and Marketing Research Laboratory, Richard B. Russcll Agricultural Research Center, Agricultural Research Service, United States...was to determine the effect of the salt phosphate treatment on rehydration. Dr. Arthur J. Mercuri, Chief, Animal Products Utilization and Marketing ... Research Laboratory served as Project Lj.ader, with Fir. A. A. Klose and Dr. W. E. Townsend, Frincipal investigators, and Ms. Brenda Lyon, Technician

  1. [Instituto de Investigaciones Clinicas "Dr. Américo Negrette": 55 years of excellent research versus global economic recession].

    PubMed

    Valero Cedeño, Nereida Josefina

    2014-12-01

    The Instituto de Investigaciones Clínicas "Dr. Américo Negrette" belongs to the Faculty of Medicine at University of Zulia in Maracaibo, Zulia State, Venezuela. It was created on December 4, 1959 by Dr. Américo Negrette. Today, with 55 years of existence, the Institute seeks to fulfill the mission that characterizes it, based on the values instilled by its founder and maintained by subsequent generations, whose research projects are implemented through seven research sections: Biochemistry, Hematologic Research, Neuropharmacology and Neuroscience, Immunology and Cell Biology, Clinical Neurochemistry, Parasitology and Virology. The research originated in these laboratories have become national and international points of reference, despite the current economic situation with budget deficits that put at risk the quality and originality of their projects with negative consequences on the productivity and applications for health population, reasons of biomedical research.

  2. Celebrating 40 Years of the Midwest Nursing Research Society.

    PubMed

    Hershberger, Patricia E; Wynd, Christine A; Glass, Laurie K; O'Connell, Karen M; Fitzpatrick, Joyce J; Bergstrom, Nancy; Lusk, Sally Lechlitner

    2017-05-01

    The Midwest Nursing Research Society (MNRS) recently held its 40th annual conference and celebrated four decades of nursing research in the Midwest. MNRS continues to be one of the largest nursing research societies in the United States. Over the years, a vast majority of programmatic initiatives included education and tangible support for novice and experienced nurse researchers. In this article, the background for development of MNRS is reviewed with examination of driving forces that led to its creation. Three past presidents, Dr. Joyce Fitzpatrick, the first President of MNRS (1980-1981); Dr. Nancy Bergstrom, the eighth President (1993-1995); and Dr. Sally Lusk, the 14th President (2005-2007), discuss challenges, opportunities, and the exceptional progress made toward fostering excellence in nursing research for the Midwest and contributing to nursing science on a national and global scale. Lessons from the past as well as opportunities for the future are addressed.

  3. New knowledge network evaluation method for design rationale management

    NASA Astrophysics Data System (ADS)

    Jing, Shikai; Zhan, Hongfei; Liu, Jihong; Wang, Kuan; Jiang, Hao; Zhou, Jingtao

    2015-01-01

    Current design rationale (DR) systems have not demonstrated the value of the approach in practice since little attention is put to the evaluation method of DR knowledge. To systematize knowledge management process for future computer-aided DR applications, a prerequisite is to provide the measure for the DR knowledge. In this paper, a new knowledge network evaluation method for DR management is presented. The method characterizes the DR knowledge value from four perspectives, namely, the design rationale structure scale, association knowledge and reasoning ability, degree of design justification support and degree of knowledge representation conciseness. The DR knowledge comprehensive value is also measured by the proposed method. To validate the proposed method, different style of DR knowledge network and the performance of the proposed measure are discussed. The evaluation method has been applied in two realistic design cases and compared with the structural measures. The research proposes the DR knowledge evaluation method which can provide object metric and selection basis for the DR knowledge reuse during the product design process. In addition, the method is proved to be more effective guidance and support for the application and management of DR knowledge.

  4. Measuring Equilibrium Binding Affinity of Biological Macromolecules in Solution by Thermophoresis

    DTIC Science & Technology

    2015-05-18

    SECURITY CLASSIFICATION OF: The primary research focus of the San Diego State University (SDSU) Structural Biochemistry Laboratory led by Dr. Tom...U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 Biochemistry , Biophysics, Fluorescence, IkappaB Kinase...University (SDSU) Structural Biochemistry Laboratory led by Dr. Tom Huxford is to understand how the assembly of macromolecular complexes gives rise

  5. A Successful Application of Latent Trait Theory to Tailored Achievement Testing.

    DTIC Science & Technology

    1980-02-01

    strategy for achieve- ment test batteries (Research Report 77-6). Minneapolis: University of Minnesota, Department of Psychology , Psychometric Methods...trait models to tailored testing (Research Report 79-1). Columbia: Uni- versity of Missouri, Department of Educational Psychology , 1979. Lord, F. M. A... Psychology Psychometric Research Group Kawauchi, Sendai 980 Educational Testing Service JAPAN Princeton, NJ 08541 Dr. Edwin Shirkey 1 Dr. Kikui

  6. Modeling the Acoustic Channel for Simulation Studies

    DTIC Science & Technology

    2012-09-30

    Michele Zorzi (PI), Prof. Gianfranco Pierobon (co-PI), Dr. Paolo Casari (post-doctoral researchers ) and Dr. Beatrice Tomasi (PhD student until 12/31...2011 and then post-doctoral researcher ), Mr. Daniele Munaretto (PhD student ), Mr. Giovanni Toso (engineer) and Mr. Matteo Lazzarin (MS student ...approach, are reported in [TWC2012]. DISSEMINATION ACTIVITIES The results obtained in the conducted reseach have been disseminated to the research

  7. 2016 AMS Mario J. Molina Symposium

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Renyi

    A named symposium to honor Dr. Mario J. Molina was held 10–14 January 2016, as part of the 96th American Meteorological Society (AMS) Annual Meeting in New Orleans, Louisiana. Dr. Molina first demonstrated that industrially produced chlorofluorocarbons (CFCs) decompose in the stratosphere and release chlorine atoms, leading to catalytic ozone destruction. His research in stratospheric chemistry was instrumental to the establishment of the 1987 United Nations Montreal Protocol to ban ozone-depleting substances worldwide. Dr. Molina’s contributions to preserving the planet Earth not only save the atmospheric ozone layer, but also protect the climate by reducing the emissions of greenhouse gases.more » He was awarded the 1995 Nobel Prize in Chemistry for his pioneering research in understanding the stratospheric ozone loss mechanism. In 2013, President Barack Obama announced Dr. Molina as a recipient of the Presidential Medal of Freedom. The 2016 AMS Molina Symposium honored Dr. Molina’s distinguished contributions to research related to atmospheric chemistry. The symposium contained an integrated theme related to atmospheric chemistry, climate, and policy. Dr. Molina delivered a keynote speech at the Symposium. The conference included invited keynote speeches and invited and contributed oral and poster sessions, and a banquet was held on Tuesday January 12, 2016. The symposium covered all aspects of atmospheric chemistry, with topics including (1) Stratospheric chemistry, (2) Tropospheric chemistry, (3) Aerosol nucleation, growth, and transformation, (4) Aerosol properties, (5) Megacity air pollution, and (6) Atmospheric chemistry laboratory, field, and modeling studies. This DOE project supported 14 scientists, including graduate students, post docs, junior research scientists, and non-tenured assistant professors to attend this symposium.« less

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, James H.

    Abstract In 1994 the Department of Energy established the DOE Chair of Excellence Professorship in Environmental Disciplines Program. In 2004, the Massie Chair of Excellence Professor at Howard University transitioned from Dr. Edward Martin to Dr. James H. Johnson, Jr. At the time of his appointment Dr. Johnson served as professor of civil engineering and Dean of the College of Engineering, Architecture and Computer Sciences. Program activities under Dr. Johnson were in the following areas: • Increase the institution’s capacity to conduct scientific research and technical investigations at the cutting-edge. • Promote interactions, collaborations and partnerships between the private sector,more » Federal agencies, majority research institutes and other HBCUs. • Assist other HBCUs in reaching parity in engineering and related fields. • Mentor young investigators and be a role model for students.« less

  9. The Manifest and Latent Functions of Differential Response in Child Welfare

    ERIC Educational Resources Information Center

    Ji, Daniel; Sullivan, Richard

    2016-01-01

    Although previous research has explored the efficacy of differential response (DR) programs in child welfare, there have been no studies to date about coding decisions between designations by child protection service agencies. Research has explored client satisfaction with DR as well as rates of recidivism and removal/placement but with limited…

  10. Static Scheduler for Hard Real-Time Tasks on Multiprocessor Systems

    DTIC Science & Technology

    1992-09-01

    Foundation of Computer Science, 1980 . [SIM83] Simons, B., "Multiprocessor Scheduling of Unit-Time Jobs with Arbitrary Release Times and Deadlines", SIAM...Research Office Attn: Dr. David Hislop P. O. Box 12211 Research Triangle Park, NC 27709-2211 31. Persistent Data Systems 75 W. Chapel Ridge Road Attn: Dr

  11. College Student Experiences Questionnaire: Norms for the Fourth Edition

    ERIC Educational Resources Information Center

    Gonyea, Robert M.; Kish, Kelly A.; Kuh, George D.; Muthiah, Richard N.; Thomas, Auden D.

    2003-01-01

    The College Student Experiences Questionnaire (CSEQ) was developed by UCLA Professor Emeritus Dr. C. Robert Pace in the 1970s. First administered by Dr. Pace in 1979, the CSEQ Research Program formally moved its operations to Indiana University's Center for Postsecondary Research and Planning in 1994, under the direction of Chancellor's Professor…

  12. Architecting Human Operator Trust in Automation to Improve System Effectiveness in Multiple Unmanned Aerial Vehicles (UAV) Control

    DTIC Science & Technology

    2009-03-01

    like to extend our appreciation to our research sponsor Dr. Janet Miller from the Air Force Research Labs, and her colleague Dr. Cheryl Batchelor, for...for single-operator control of multiple UAVs. Drs. Brian Tsou, Lamar Warfield , Justin Estepp and Benjamin Knott , meanwhile, contributed to our

  13. Dr. Robert G. Heath: a controversial figure in the history of deep brain stimulation.

    PubMed

    O'Neal, Christen M; Baker, Cordell M; Glenn, Chad A; Conner, Andrew K; Sughrue, Michael E

    2017-09-01

    The history of psychosurgery is filled with tales of researchers pushing the boundaries of science and ethics. These stories often create a dark historical framework for some of the most important medical and surgical advancements. Dr. Robert G. Heath, a board-certified neurologist, psychiatrist, and psychoanalyst, holds a debated position within this framework and is most notably remembered for his research on schizophrenia. Dr. Heath was one of the first physicians to implant electrodes in deep cortical structures as a psychosurgical intervention. He used electrical stimulation in an attempt to cure patients with schizophrenia and as a method of conversion therapy in a homosexual man. This research was highly controversial, even prior to the implementation of current ethics standards for clinical research and often goes unmentioned within the historical narrative of deep brain stimulation (DBS). While distinction between the modern practice of DBS and its controversial origins is necessary, it is important to examine Dr. Heath's work as it allows for reflection on current neurosurgical practices and questioning the ethical implication of these advancements.

  14. Proceedings of the Annual Conference: Rehabilitation Research and Training Centers of the National Institute of Handicapped Research. Meeting the Opportunities of the National Institute of Handicapped Research (4th, Washington, D.C., May 5-7, 1980). Special Edition.

    ERIC Educational Resources Information Center

    Informer, 1980

    1980-01-01

    Keynoted by Dr. Margaret J. Giannini, Director of the National Institute of Handicapped Research (NIHR), these conference proceedings focus on present concerns and future issues facing the NIHR and researchers and trainers in the field of rehabilitation of the handicapped. In her address, Dr. Giannini outlines priorities for the NIHR for the next…

  15. Founders hope new venture-capital fund will spur medical, biotechnology research

    PubMed Central

    Gray, Charlotte

    1995-01-01

    Lack of a coherent industrial strategy and venture capital have hindered scientific researchers in Canada, but the Canadian Medical Discoveries Fund (CMDF) Inc. hopes to change that. Under the leadership of Dr. Henry Friesen, president of the Medical Research Council of Canada, and Dr. Calvin Stiller, head of the multiorgan transplant unit at University Hospital, London, Ont., the new fund proposes to invest in promising medical and biotechnology research companies in Canada. The research council's peerreview system gives the new fund scientific credibility.

  16. Characteristics and Dose Levels for Spent Reactor Fuels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coates, Cameron W

    2007-01-01

    Current guidance considers highly radioactive special nuclear materials to be those materials that, unshielded, emit a radiation dose [rate] measured at 1 m which exceeds 100 rem/h. Smaller, less massive fuel assemblies from research reactors can present a challenge from the point of view of self protection because of their size (lower dose, easier to handle) and the desirability of higher enrichments; however, a follow-on study to cross-compare dose trends of research reactors and power reactors was deemed useful to confirm/verify these trends. This paper summarizes the characteristics and dose levels of spent reactor fuels for both research reactors andmore » power reactors and extends previous studies aimed at quantifying expected dose rates from research reactor fuels worldwide.« less

  17. International Intercomparison Exercise for Nuclear Accident Dosimetry at the DAF Using GODIVA-IV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hickman, David; Hudson, Becka

    The Nuclear Criticality Safety Program operated under the direction of Dr. Jerry McKamy completed the first NNSA Nuclear Accident Dosimetry exercise on May 27, 2016. Participants in the exercise were from Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Sandia National Laboratory (SNL), Savanah River Site (SRS), Pacific Northwest National Laboratory (PNNL), US Navy, the Atomic Weapons Establishment (United Kingdom) under the auspices of JOWOG 30, and the Institute for Radiological Protection and Nuclear Safety (France) by special invitation and NCSP memorandum of understanding. This exercise was the culmination of a series of Integral Experiment Requests (IER) thatmore » included the establishment of the Nuclear Criticality Experimental Research Center, (NCERC) the startup of the Godiva Reactor (IER-194), the establishment of a the Nuclear Accident Dosimetry Laboratory (NAD LAB) in Mercury, NV, and the determination of reference dosimetry values for the mixed neutron and photon radiation field of Godiva within NCERC.« less

  18. Mass Spectrometric Thermal Decomposition and Ultraviolet Irradiation Studies of Some Azido and Nitrato Polymeric Binders.

    DTIC Science & Technology

    1982-09-01

    Edwards AFB, CA 93523 Attn: Mr. D. Siegel Attn: Dr. F. Roberto Office of Naval Research 1 AFSC Western Office Andrews AFB, Code DLFP 1030 East Green...Office space Sciences One Hallidie Plaza Suite 601 Bolling Air Force Base San Francisco, CA 94102 Washing.on, DC 20332 Attn: Dr. P. A. Miller Attn: Dr

  19. RT 164: Design and Development Tools for the Systems Engineering Experience Accelerator - Part 3

    DTIC Science & Technology

    2017-04-29

    Investigator: Dr. Jon Wade, Stevens Institute of Technology Co-Principal Investigator: Dr. Doug Bodner, Georgia Institute of Technology Research Team...Defense Acquisition University: Yvette Rodriguez Georgia Institute of Technology : Jing Liu Stevens Institute of Technology : Dr. Richard Turner...Stevens Institute of Technology : Peizhu Zhang Sponsor: Office of the DASD (Systems Engineering) Report No. SERC-2017-TR-107

  20. Cyber Flag: A Realistic Cyberspace Training Construct

    DTIC Science & Technology

    2008-03-27

    sincere appreciation to my research committee, Dr Mark Kanko, Dr Bob Bills , and Dr Rick Raines, as well as my faculty advisor, Major Paul Williams ...Graduate School of Engineering and Management Air Force Institute of Technology Air University Air Education and Training Command In Partial... Williams , Ph.D. (Chairman) date ___________//SIGNED//________________ 22 Jan 08 Mark A. Kanko, Ph.D. (Member) date

  1. Enrico Fermi Awards Ceremony for Dr. Mildred S. Dresselhaus and Dr. Burton Richter, May 2012 (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

    ScienceCinema

    Chu, Steven [Dept. of Energy (DOE), Washington DC (United States)

    2018-06-12

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadership as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.

  2. Human radiation studies: Remembering the early years: Oral history of health physicist Karl Z. Morgan, Ph.D., conducted January 7, 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-06-01

    This report provided a transcript of an interview of Dr. Karl. Z. Morgan by representatives of the DOE Office of Human Radiation Experiments. Dr. Morgan was selected for this interview because of his research for the Manhattan Project at the Metallurgical Laboratory in Chicago and his work at the Oak Ridge National Laboratory (ORNL). The oral history covers Dr. Morgan`s work as a pioneer in the field of Health Physics, his research at ORNL and his work since he retired from ORNL.

  3. CDAC Student Report: Summary of LLNL Internship

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Herriman, Jane E.

    Multiple objectives motivated me to apply for an internship at LLNL: I wanted to experience the work environment at a national lab, to learn about research and job opportunities at LLNL in particular, and to gain greater experience with code development, particularly within the realm of high performance computing (HPC). This summer I was selected to participate in LLNL's Computational Chemistry and Material Science Summer Institute (CCMS). CCMS is a 10 week program hosted by the Quantum Simulations group leader, Dr. Eric Schwegler. CCMS connects graduate students to mentors at LLNL involved in similar re- search and provides weekly seminarsmore » on a broad array of topics from within chemistry and materials science. Dr. Xavier Andrade and Dr. Erik Draeger served as my co-mentors over the summer, and Dr. Andrade continues to mentor me now that CCMS has concluded. Dr. Andrade is a member of the Quantum Simulations group within the Physical and Life Sciences at LLNL, and Dr. Draeger leads the HPC group within the Center for Applied Scientific Computing (CASC). The two have worked together to develop Qb@ll, an open-source first principles molecular dynamics code that was the platform for my summer research project.« less

  4. Model-based optimal design of active cool thermal energy storage for maximal life-cycle cost saving from demand management in commercial buildings

    DOE PAGES

    Cui, Borui; Gao, Dian-ce; Xiao, Fu; ...

    2016-12-23

    This article provides a method in comprehensive evaluation of cost-saving potential of active cool thermal energy storage (CTES) integrated with HVAC system for demand management in non-residential building. The active storage is beneficial by shifting peak demand for peak load management (PLM) as well as providing longer duration and larger capacity of demand response (DR). In this research, a model-based optimal design method using genetic algorithm is developed to optimize the capacity of active CTES aiming for maximizing the life-cycle cost saving concerning capital cost associated with storage capacity as well as incentives from both fast DR and PLM. Inmore » the method, the active CTES operates under a fast DR control strategy during DR events while under the storage-priority operation mode to shift peak demand during normal days. The optimal storage capacities, maximum annual net cost saving and corresponding power reduction set-points during DR event are obtained by using the proposed optimal design method. Lastly, this research provides guidance in comprehensive evaluation of cost-saving potential of CTES integrated with HVAC system for building demand management including both fast DR and PLM.« less

  5. Model-based optimal design of active cool thermal energy storage for maximal life-cycle cost saving from demand management in commercial buildings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cui, Borui; Gao, Dian-ce; Xiao, Fu

    This article provides a method in comprehensive evaluation of cost-saving potential of active cool thermal energy storage (CTES) integrated with HVAC system for demand management in non-residential building. The active storage is beneficial by shifting peak demand for peak load management (PLM) as well as providing longer duration and larger capacity of demand response (DR). In this research, a model-based optimal design method using genetic algorithm is developed to optimize the capacity of active CTES aiming for maximizing the life-cycle cost saving concerning capital cost associated with storage capacity as well as incentives from both fast DR and PLM. Inmore » the method, the active CTES operates under a fast DR control strategy during DR events while under the storage-priority operation mode to shift peak demand during normal days. The optimal storage capacities, maximum annual net cost saving and corresponding power reduction set-points during DR event are obtained by using the proposed optimal design method. Lastly, this research provides guidance in comprehensive evaluation of cost-saving potential of CTES integrated with HVAC system for building demand management including both fast DR and PLM.« less

  6. Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

    ScienceCinema

    Moniz, Ernest; Dehmer, Patricia

    2018-05-04

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of the research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.

  7. Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moniz, Ernest; Dehmer, Patricia

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of themore » research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.« less

  8. 50 Years of renal physiology from one man and the perfused tubule: Maurice B. Burg.

    PubMed

    Hamilton, Kirk L; Moore, Antoni B

    2016-08-01

    Technical advancements in research techniques in science are made in slow increments. Even so, large advances from insight and hard work of an individual with a single technique can have astonishing ramifications. Here, we examine the impact of Dr. Maurice B. Burg and the isolated perfused renal tubule technique and celebrate the 50th anniversary of the publication by Dr. Burg and his colleagues of their landmark paper in the American Journal of Physiology in 1966. In this study, we have taken a scientific visualization approach to study the scientific contributions of Dr. Burg and the isolated perfused tubule preparation as determining research impact by the number of research students, postdoctoral fellows, visiting scientists, and national and international collaborators. Additionally, we have examined the research collaborations (first and second generation scientists), established the migrational visualization of the first generation scientists who worked directly with Dr. Burg, quantified the metrics indices, identified and quantified the network of coauthorship of the first generation scientists with their second generation links, and determined the citations analyses of outputs of Dr. Burg and/or his first generation collaborators as coauthors. We also review the major advances in kidney physiology that have been made with the isolated perfused tubule technique. Finally, we are all waiting for the discoveries that the isolated perfused preparation technique will bring during the next 50 years. Copyright © 2016 the American Physiological Society.

  9. Exploiting Auxiliary Information about Examinees in the Estimation of Item Parameters.

    DTIC Science & Technology

    1986-05-01

    Research. The author is grateful to Kathleen Sheehan and Martha Stocking for their comments and suggestions. a, • ... Am -. ,** . Exploiting...Research Laboratory Dr. Hans Crombag 103 South Mathews Street University of Leyden Urbana, IL 61801 Education Research Center Boerhaavelaan 2 Dr. Susan...Embretson 23-4 EN Leyden University of Kansas The NETHERLANDS Psychology Department Lawrence, KS 66045 CTR/McGraw-Hill Library 2500 Garden Road ERIC

  10. Forecasting Climate-Induced Ecosystem Changes on Army Installations

    DTIC Science & Technology

    2011-10-01

    W. Hargrove Construction Engineering Research Laboratory (CERL) US Army Engineer Research and Development Center 2902 Newmark Dr. Champaign, IL...unless so designated by other authorized documents. DESTROY THIS REPORT WHEN NO LONGER NEEDED. DO NOT RETURN IT TO THE ORIGINATOR. ERDC/CERL TR-11-36...35 ERDC/CERL TR-11-36 v Preface This study was conducted for Dr. Jeffrey Holland, Director of the Engineer Research and Development

  11. Knowledge Acquisition for Expert Systems in Construction

    DTIC Science & Technology

    1988-12-01

    following scientific personnel have been closely involved in the execution of this research : Dr R J Allwood Mr A E Bryman Mr C N Cooper Dr J Cullen Mr...alternative methods and should use them flexibly as the position unfolds. This approach has been advocated by other researchers (eg Cordingley - see Diaper...currently engaged in research into methods of knowledge acquisition for expert systems. Although their original focus was on construction industry

  12. Everything is connected: social determinants of pediatric health and disease.

    PubMed

    Tarazi, Carine; Skeer, Margie; Fiscella, Kevin; Dean, Stephanie; Dammann, Olaf

    2016-01-01

    Carine Tarazi, MA, is an Assistant Editor for Pediatric Research in Boston, Massachusetts, USA. Margie Skeer, ScD, MPH, MSW, served as a Guest Editor for this special issue. Dr. Skeer is Assistant Professor of Public Health and Community Medicine at Tufts University. Her research focuses on adolescent substance misuse and sexual risk prevention, both from epidemiologic and intervention-development perspectives. Kevin Fiscella, MD, MPH, served as a Guest Editor for this special issue. Dr. Fiscella is Tenured Professor of Family Medicine, Public Health Sciences and Community Health at the University of Rochester Medical Center. Dr. Fiscella's research focuses on health and health care disparities, particularly practical strategies to improve health equity. Stephanie Dean, MBA, is Managing Editor of Pediatric Research and is based out of editorial office in The Woodlands, Texas. Olaf Dammann, MD, served as a Guest Editor for this special issue. Dr. Dammann is a Professor of Public Health and Community Medicine, Pediatrics, and Ophthalmology at Tufts University School of Medicine in Boston, Massachusetts, USA, as well as Professor of Perinatal Neuroepidemiology at Hannover Medical School, Hannover, Germany. His research interests include the elucidation of risk factors for brain damage and retinopathy in preterm newborns, the theory of risk and causation in biomedical and public health research, and the development of computational chronic disease models.

  13. Twelve Scientific Specialists of the Peenemuende Team

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Twelve scientific specialists of the Peenemuende team at the front of Building 4488, Redstone Arsenal, Huntsville, Alabama. They led the Army's space efforts at ABMA before transfer of the team to National Aeronautic and Space Administration (NASA), George C. Marshall Space Flight Center (MSFC). (Left to right) Dr. Ernst Stuhlinger, Director, Research Projects Office; Dr. Helmut Hoelzer, Director, Computation Laboratory: Karl L. Heimburg, Director, Test Laboratory; Dr. Ernst Geissler, Director, Aeroballistics Laboratory; Erich W. Neubert, Director, Systems Analysis Reliability Laboratory; Dr. Walter Haeussermarn, Director, Guidance and Control Laboratory; Dr. Wernher von Braun, Director Development Operations Division; William A. Mrazek, Director, Structures and Mechanics Laboratory; Hans Hueter, Director, System Support Equipment Laboratory;Eberhard Rees, Deputy Director, Development Operations Division; Dr. Kurt Debus, Director Missile Firing Laboratory; Hans H. Maus, Director, Fabrication and Assembly Engineering Laboratory

  14. Origin of Marshall Space Flight Center (MSFC)

    NASA Image and Video Library

    2004-04-15

    Twelve scientific specialists of the Peenemuende team at the front of Building 4488, Redstone Arsenal, Huntsville, Alabama. They led the Army's space efforts at ABMA before transfer of the team to National Aeronautic and Space Administration (NASA), George C. Marshall Space Flight Center (MSFC). (Left to right) Dr. Ernst Stuhlinger, Director, Research Projects Office; Dr. Helmut Hoelzer, Director, Computation Laboratory: Karl L. Heimburg, Director, Test Laboratory; Dr. Ernst Geissler, Director, Aeroballistics Laboratory; Erich W. Neubert, Director, Systems Analysis Reliability Laboratory; Dr. Walter Haeussermarn, Director, Guidance and Control Laboratory; Dr. Wernher von Braun, Director Development Operations Division; William A. Mrazek, Director, Structures and Mechanics Laboratory; Hans Hueter, Director, System Support Equipment Laboratory;Eberhard Rees, Deputy Director, Development Operations Division; Dr. Kurt Debus, Director Missile Firing Laboratory; Hans H. Maus, Director, Fabrication and Assembly Engineering Laboratory

  15. Social Environmental Influences on the Development and Resolution of Alcohol Problems

    PubMed Central

    McCrady, Barbara S.; Zucker, Robert A.; Molina, Brooke S. G.; Ammon, Lyndsay; Ames, Genevieve M.; Longabaugh, Richard

    2006-01-01

    This article summarizes the proceedings of a symposium presented at the 2005 Annual Meeting of the Research Society on Alcoholism, Santa Barbara, California, June 25–30. The overall goal of the symposium was to consider the broad impact of the social environment on the development of and successful or unsuccessful resolution of drinking problems. The presentations addressed multiple social environmental influences including: the influence of children on parents (Dr. Zucker), the influence of peers and parents on adolescents (Dr. Molina), the influence of family members on adult drinking (Dr. McCrady), the influence of adult peers/friends (Dr. Kaskutas), and the influence of the occupational environment (Dr. Ames). Dr. Longabaugh, the symposium discussant, addressed models for understanding the relationships between social influences and drinking problems. PMID:16573588

  16. Bruce Thompson: Adventures and advances in ultrasonic backscatter

    NASA Astrophysics Data System (ADS)

    Margetan, Frank J.

    2012-05-01

    Over the course of his professional career Dr. R. Bruce Thompson published several hundred articles on non-destructive evaluation, the majority dealing with topics in ultrasonics. One longtime research interest of Dr. Thompson, with applications both to microstructure characterization and defect detection, was backscattered grain noise in metals. Over a 20 year period he led a revolving team of staff members and graduate students investigating various aspects of ultrasonic backscatter. As a member of that team I had the privilege of working along side Dr. Thompson for many years, serving as a sort of Dr. Watson to Bruce's Sherlock Holmes. This article discusses Dr. Thompson's general approaches to modeling backscatter, the research topics he chose to explore to systematically elucidate a better understanding of the phenomena, and the many contributions to the field achieved under his leadership. The backscatter work began in earnest around 1990, motivated by a need to improve inspections of aircraft engine components. At that time Dr. Thompson launched two research efforts. The first led to the heuristic Independent Scatterer Model which could be used to estimate the average grain noise level that would be seen in any given ultrasonic inspection. There the contribution from the microstructure was contained in a measureable parameter known as the Figure-of-Merit or FOM. The second research effort, spearheaded by Dr. Jim Rose, led to a formal relationship between FOM and details of the metal microstructure. The combination of the Independent Scattering Model and Rose's formalism provided a powerful tool for investigating backscatter in metals. In this article model developments are briefly reviewed and several illustrative applications are discussed. These include: the determination of grain size and shape from ultrasonic backscatter; grain noise variability in engine-titanium billets and forgings; and the design of ultrasonic inspection systems to improve defect-signal-to-grain-noise ratios.

  17. Multiplying Electrons With Diamond

    NASA Technical Reports Server (NTRS)

    2003-01-01

    As researchers in the Space Communications Division of NASA s Glenn Research Center in 1992, Dr. Gerald Mearini, Dr. Isay Krainsky, and Dr. James Dayton made a secondary electron emission discovery that became the foundation for Mearini s company, GENVAC AeroSpace Corporation. Even after Mearini departed Glenn, then known as Lewis Research Center, his contact with NASA remained strong as he was awarded Small Business Innovation Research (SBIR) contracts to further develop his work. Mearini s work for NASA began with the investigation of diamond as a material for the suppression of secondary electron emissions. The results of his research were the opposite of what was expected diamond proved to be an excellent emitter rather than absorber. Mearini, Krainsky, and Dayton discovered that laboratory-grown diamond films can produce up to 45 electrons from a single incident electron. Having built an electron multiplier prototype at NASA, Mearini decided to start his own company to develop diamond structures usable in electron beam devices.

  18. An Automated Detection System for Microaneurysms That Is Effective across Different Racial Groups.

    PubMed

    Saleh, George Michael; Wawrzynski, James; Caputo, Silvestro; Peto, Tunde; Al Turk, Lutfiah Ismail; Wang, Su; Hu, Yin; Da Cruz, Lyndon; Smith, Phil; Tang, Hongying Lilian

    2016-01-01

    Patients without diabetic retinopathy (DR) represent a large proportion of the caseload seen by the DR screening service so reliable recognition of the absence of DR in digital fundus images (DFIs) is a prime focus of automated DR screening research. We investigate the use of a novel automated DR detection algorithm to assess retinal DFIs for absence of DR. A retrospective, masked, and controlled image-based study was undertaken. 17,850 DFIs of patients from six different countries were assessed for DR by the automated system and by human graders. The system's performance was compared across DFIs from the different countries/racial groups. The sensitivities for detection of DR by the automated system were Kenya 92.8%, Botswana 90.1%, Norway 93.5%, Mongolia 91.3%, China 91.9%, and UK 90.1%. The specificities were Kenya 82.7%, Botswana 83.2%, Norway 81.3%, Mongolia 82.5%, China 83.0%, and UK 79%. There was little variability in the calculated sensitivities and specificities across the six different countries involved in the study. These data suggest the possible scalability of an automated DR detection platform that enables rapid identification of patients without DR across a wide range of races.

  19. NORSAR Basic Seismological Research

    DTIC Science & Technology

    1990-11-29

    AZ 85721 Prof. Christopher H. Scholz Dr. William Wortman Lamont-Doherty Geological Observatory Mission Research Corporation of Columbia University 735...Reston, VA 22091 Mr. William J. Best Prof. Robert W. Clayton 907 Westwood Drive Seismological Laboratory Vienna, VA 22180 Division of Geological...Planetary Sciences California Institute of Technology Pasadena, CA 91125 Dr. N. Biswas Prof. F. A. Dahlen Geophysical Institute Geological and Geophysical

  20. 78 FR 24197 - Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ...; NY050002; OH030003). IN 46268-1054. 66330 Arysta Life Science North America, LLC, 15401 Weston Parkway... (ME090004) Bayer CropScience LP, 2 T.W. Alexander Dr., P.O. Box 12014, Research Triangle Park, NC 27709. 432 Bayer Environmental Science, 2 T.W. Alexander Dr., P.O. Box 12014, Research Triangle Park, NC 27709. 675...

  1. American Graduate Schools of Education. A View from Abroad.

    ERIC Educational Resources Information Center

    Judge, Harry G.

    Dr. Harry G. Judge of Oxford University, England, was asked by the Ford Foundation to conduct a series of visits to American research universities and their schools of education. His purpose was to investigate the role of the school of education in the research university, particularly at the graduate level. Dr. Judge visited ten universities and…

  2. Validity of electronic diet recording nutrient estimates compared to dietitian analysis of diet records: A randomized controlled trial

    USDA-ARS?s Scientific Manuscript database

    Background: Dietary intake assessment with diet records (DR) is a standard research and practice tool in nutrition. Manual entry and analysis of DR is time-consuming and expensive. New electronic tools for diet entry by clients and research participants may reduce the cost and effort of nutrient int...

  3. A Critical Appraisal of Issues in Differential Response: Moving the Field Forward

    ERIC Educational Resources Information Center

    Winokur, Marc A.; Gabel, George

    2013-01-01

    This reaction article highlights areas of agreement and disagreement with the study conducted by Hughes, Rycus, Saunders-Adams, Hughes, and Hughes on the current state of research and practice in differential response (DR). Overall, we agree with several of the arguments put forth by Hughes et al. regarding the limitations of DR research and the…

  4. Highly Inventive Explorer of Creativity: An Interview with John Baer

    ERIC Educational Resources Information Center

    Henshon, Suzanna E.

    2009-01-01

    Dr. John Baer is a Professor in the Department of Teacher Education at Rider University. Dr. Baer has published 10 books and scores of research articles and book chapters on creativity, cooperative learning, and other educational psychology topics. His research on the development of creativity and his teaching have both won national awards,…

  5. Spring Research Festival Features Visit from FCPS Superintendent | Poster

    Cancer.gov

    One of the highlights of the 19th annual Spring Research Festival (SRF), held May 4–7, was a visit from Terry Alban, Ph.D., superintendent of Frederick County Public Schools (FCPS), and Mike Markoe, deputy superintendent, FCPS. They toured the event on May 7, talking to researchers and students about their posters. “Dr. Alban was very interested in hearing what the Werner H. Kirsten students were presenting at their posters,” said Andrea Frydl, public affairs specialist, Office of Scientific Operations, NCI at Frederick. “Many WHK students are also FCPS students, some of whom Dr. Alban and Dr. Markoe knew personally.” Alban tweeted (@FCPSMDSuper) photos and information about four of the students whose posters she visited during the tour.

  6. Tough on Crime? Pfizer and the CIHR

    PubMed Central

    Evans, Robert G.

    2010-01-01

    The appointment of Dr. Bernard Prigent, vice-president and medical director of Pfizer Canada, to the Governing Council of the Canadian Institutes of Health Research, outraged many Canadian health researchers. Pfizer has been a “habitual offender,” persistently engaging in illegal and corrupt marketing practices, bribing physicians and suppressing adverse trial results. Since 2002 the company and its subsidiaries have been assessed $3 billion in criminal convictions, civil penalties and jury awards. The $2.3-billion settlement in September 2009 – a month before Dr. Prigent's appointment – set a new record for both criminal fines and total penalties. A link with Pfizer might well advance the commercialization of Canadian research – unhindered by law or morality. Is that now the only mandate, Dr. Beaudet? PMID:21532766

  7. Answering Questions from Oceanography Texts: Learner, Task and Text Characteristics.

    DTIC Science & Technology

    1987-09-15

    1 275-290. ’S.= Stowe, K. (1983). S , 2nd edition. New York, NY: John Wiley & Sons. ’?o.,i ’S= .. ’S.’ .5.% .5.% r. ** - ’, .* . . . % S 9.. . 9...94305 O Dr. Ed Aiken Leo Seltracchi Dr. John S. Brown " Navy Personnel R&D Center U. S. Nuclear Regulatory Comm. XEROX Palo Alto Research Center " San...iego, CA 92152-6800 Washington, OC 20555 3333 Coyote Hill Road Palo Alto, CA 94304 Or. John R. Anderson Dr. Mark H. Bickhard Dr. Ann Brown Department

  8. Wernher von Braun

    NASA Image and Video Library

    1965-05-25

    This image depicts the tension in the Launch Control Center of the Launch Complex 37 at Cape Canaveral, Florida, during the SA-8 on May 25, 1965. Pointing, center is Dr. Kurt Debus, Director, Launch Operations Directorate, MSFC. To the right is Dr. Hans Gruene, Deputy Director, Launch Operations Directorate, MSFC; Dr. von Braun, Director, Marshall Space Flight Center (MSFC); and leaning, Dr. Eberhard Rees, Director, Deputy Director for Research and Development, MSFC. The SA-8 mission, with a Saturn I launch vehicle, made the first night launch and deployed Pegasus II, micrometeoroid detection satellite.

  9. MSeqDR: A Centralized Knowledge Repository and Bioinformatics Web Resource to Facilitate Genomic Investigations in Mitochondrial Disease.

    PubMed

    Shen, Lishuang; Diroma, Maria Angela; Gonzalez, Michael; Navarro-Gomez, Daniel; Leipzig, Jeremy; Lott, Marie T; van Oven, Mannis; Wallace, Douglas C; Muraresku, Colleen Clarke; Zolkipli-Cunningham, Zarazuela; Chinnery, Patrick F; Attimonelli, Marcella; Zuchner, Stephan; Falk, Marni J; Gai, Xiaowu

    2016-06-01

    MSeqDR is the Mitochondrial Disease Sequence Data Resource, a centralized and comprehensive genome and phenome bioinformatics resource built by the mitochondrial disease community to facilitate clinical diagnosis and research investigations of individual patient phenotypes, genomes, genes, and variants. A central Web portal (https://mseqdr.org) integrates community knowledge from expert-curated databases with genomic and phenotype data shared by clinicians and researchers. MSeqDR also functions as a centralized application server for Web-based tools to analyze data across both mitochondrial and nuclear DNA, including investigator-driven whole exome or genome dataset analyses through MSeqDR-Genesis. MSeqDR-GBrowse genome browser supports interactive genomic data exploration and visualization with custom tracks relevant to mtDNA variation and mitochondrial disease. MSeqDR-LSDB is a locus-specific database that currently manages 178 mitochondrial diseases, 1,363 genes associated with mitochondrial biology or disease, and 3,711 pathogenic variants in those genes. MSeqDR Disease Portal allows hierarchical tree-style disease exploration to evaluate their unique descriptions, phenotypes, and causative variants. Automated genomic data submission tools are provided that capture ClinVar compliant variant annotations. PhenoTips will be used for phenotypic data submission on deidentified patients using human phenotype ontology terminology. The development of a dynamic informed patient consent process to guide data access is underway to realize the full potential of these resources. © 2016 WILEY PERIODICALS, INC.

  10. MSeqDR: A Centralized Knowledge Repository and Bioinformatics Web Resource to Facilitate Genomic Investigations in Mitochondrial Disease

    PubMed Central

    Shen, Lishuang; Diroma, Maria Angela; Gonzalez, Michael; Navarro-Gomez, Daniel; Leipzig, Jeremy; Lott, Marie T.; van Oven, Mannis; Wallace, Douglas C.; Muraresku, Colleen Clarke; Zolkipli-Cunningham, Zarazuela; Chinnery, Patrick F.; Attimonelli, Marcella; Zuchner, Stephan

    2016-01-01

    MSeqDR is the Mitochondrial Disease Sequence Data Resource, a centralized and comprehensive genome and phenome bioinformatics resource built by the mitochondrial disease community to facilitate clinical diagnosis and research investigations of individual patient phenotypes, genomes, genes, and variants. A central Web portal (https://mseqdr.org) integrates community knowledge from expert-curated databases with genomic and phenotype data shared by clinicians and researchers. MSeqDR also functions as a centralized application server for Web-based tools to analyze data across both mitochondrial and nuclear DNA, including investigator-driven whole exome or genome dataset analyses through MSeqDR-Genesis. MSeqDR-GBrowse supports interactive genomic data exploration and visualization with custom tracks relevant to mtDNA variation and disease. MSeqDR-LSDB is a locus specific database that currently manages 178 mitochondrial diseases, 1,363 genes associated with mitochondrial biology or disease, and 3,711 pathogenic variants in those genes. MSeqDR Disease Portal allows hierarchical tree-style disease exploration to evaluate their unique descriptions, phenotypes, and causative variants. Automated genomic data submission tools are provided that capture ClinVar-compliant variant annotations. PhenoTips is used for phenotypic data submission on de-identified patients using human phenotype ontology terminology. Development of a dynamic informed patient consent process to guide data access is underway to realize the full potential of these resources. PMID:26919060

  11. Learning about Gaucher Disease

    MedlinePlus

    ... Links for Patient Care Education All About the Human Genome Project Fact Sheets Genetic Education Resources for Teachers ... at the Medical Genetics Branch of the National Human Genome Research Institute by Dr. Ellen Sidransky. Dr. Sidransky ...

  12. Costs to Automate Demand Response - Taxonomy and Results from Field Studies and Programs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Piette, Mary A.; Schetrit, Oren; Kiliccote, Sila

    During the past decade, the technology to automate demand response (DR) in buildings and industrial facilities has advanced significantly. Automation allows rapid, repeatable, reliable operation. This study focuses on costs for DR automation in commercial buildings with some discussion on residential buildings and industrial facilities. DR automation technology relies on numerous components, including communication systems, hardware and software gateways, standards-based messaging protocols, controls and integration platforms, and measurement and telemetry systems. This report compares cost data from several DR automation programs and pilot projects, evaluates trends in the cost per unit of DR and kilowatts (kW) available from automated systems,more » and applies a standard naming convention and classification or taxonomy for system elements. Median costs for the 56 installed automated DR systems studied here are about $200/kW. The deviation around this median is large with costs in some cases being an order of magnitude great or less than the median. This wide range is a result of variations in system age, size of load reduction, sophistication, and type of equipment included in cost analysis. The costs to automate fast DR systems for ancillary services are not fully analyzed in this report because additional research is needed to determine the total cost to install, operate, and maintain these systems. However, recent research suggests that they could be developed at costs similar to those of existing hot-summer DR automation systems. This report considers installation and configuration costs and does include the costs of owning and operating DR automation systems. Future analysis of the latter costs should include the costs to the building or facility manager costs as well as utility or third party program manager cost.« less

  13. 2014 Sensorimotor Risk Standing Review Panel

    NASA Technical Reports Server (NTRS)

    Steinberg, Susan

    2014-01-01

    The Sensorimotor Risk Standing Review Panel (from here on referred to as the SRP) met on December 17 - 18, 2014 in Houston, TX to review the current status of the Risk of Impaired Control of Spacecraft, Associated Systems and Immediate Vehicle Egress due to Vestibular/Sensorimotor Alteration Associated with Space Flight (Sensorimotor Risk) in the Integrated Research Plan (IRP). During the meeting, the SRP received an in-depth briefing of the current status of the Sensorimotor Risk from Dr. Jacob Bloomberg, the Human Research Program (HRP) Sensorimotor Discipline Lead Scientist and Dr. Millard Reschke, the Chief Scientist of the Neuroscience Laboratories at the NASA Johnson Space Center (JSC). The SRP was impressed with the information that Dr. Bloomberg and Dr. Reschke presented and think that the in-person meeting (instead of WebEx/teleconference) allowed for more interactive and thoughtful conversations.

  14. Stability Analysis of Plates and Shells

    NASA Technical Reports Server (NTRS)

    Knight, Norman F., Jr. (Compiler); Nemeth, Michael P. (Compiler)

    1998-01-01

    This special publication contains the papers presented at the special sessions honoring Dr. Manuel Stein during the 38th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference held in Kissimmee, Florida, Apdl 7-10, 1997. This volume, and the SDM special sessions, are dedicated to the memory of Dr. Manuel Stein, a major pioneer in structural mechanics, plate and shell buckling, and composite structures. Many of the papers presented are the work of Manny's colleagues and co-workers and are a result, directly or indirectly, of his influence. Dr. Stein earned his Ph.D. in Engineering Mechanics from Virginia Polytechnic Institute and State University in 1958. He worked in the Structural Mechanics Branch at the NASA Langley Research Center from 1943 until 1989. Following his retirement, Dr. Stein continued his involvement with NASA as a Distinguished Research Associate.

  15. Commentary: the role of epidemiologists in funding biomedical education and research.

    PubMed

    Perry, Melissa J

    2016-09-01

    Melissa Perry served as the president of the American College of Epidemiology from September 2014 to September 2015. This is a written version of her Presidential Address at the 2015 Annual Meeting. Her speech was inspired by a 2014 Wall Street Journal commentary by Dr. Ferric Fang of the Washington University School of Medicine and Dr. Arturo Casadevall of the Albert Einstein College of Medicine of Yeshiva University. They likened the process of submitting a research proposal to the National Institutes of Health to playing the Powerball lottery. In her speech, Dr. Perry argued for the urgent need for epidemiology researchers to reach out to policymakers and the public in support of our field to ensure the continuation of research projects that can help improve the health of citizens everywhere. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Which is riskier: windmills or reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cromie, W.J.

    1980-03-01

    In 1978, Dr. Herbert Inhaber, a scientist employed by the Atomic Energy Board of Canada, published an evaluation of the health hazards of different energy systems entitled Risk of Energy Production. He concluded that natural gas and nuclear systems are safer than coal- and oil-fired power plants, hydroelectricity, various forms of solar energy, windmills, methanol (wood alcohol), and other nonconventional energy sources. The report and its conclusions drew widespread criticism, particularly from Dr. John P. Holdren, professor of energy and resources, University of California at Berkeley. Holdren and five colleagues wrote a stinging 232-page critique of the Inhaber report. Themore » Council for the Advancement of Science Writing, a nonprofit educational organization of writers and scientists, invited the two to debate the issue in front of an audience of science reporters. The confrontation took place at CASW's 17th Annual New Horizons in Science Briefing in Palo Alto, Calif., on Nov. 5, 1979. An edited transcript of the debate is presented here.« less

  17. Discovery of heavy hydrogen and heavy water. Internal report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saylor, C.P.

    1983-10-01

    This report is a brief account prepared by request of Walter Weinstein for Dr. C. P. Saylor some years prior to his death in April 1982. It has been carefully reviewed by several present and former staff members, including former NBS scientis, Dr. F. G. Brickwedde, who participated with Dr. Harold C. Urey and others in the experiments and events described by Saylor. In his review Dr. Brickwedde, now Evans Pugh Research Professor of Physics emeritus at Pennsylvania State University, stated that 'Dr. Saylor's paper covers an important part of the history of the discovery of deuterium that is notmore » so well known ... and contains information important for the chemical historian.« less

  18. Committee for International Conference on Mechanical Engineering Research (ICMER 2011)

    NASA Astrophysics Data System (ADS)

    Yusoff, Ahmad Razlan Bin

    2012-09-01

    Scientific Advisory Committee: 1) Prof. Dr. Ahmad Kamal Ariffin (UKM) 2) Prof. Dr. Hj. Rosli Abu Bakar (UMP) 3) Prof. Dr. Hanafi Ismail (USM) 4) Prof. Ir. Dr. Mohd Jailani Mohd Nor (MoHE) 5) Prof. Dr. Zahari Taha (UMP) 6) Prof. Dr. Masjuki Haji Hassan 7) Prof. Ir. Dr. Ramesh Singh (UNITEN) 8) Prof. Dr. Razali Ayob (UTEM) 9) Prof. Dr. Wan Khairuddin (UTM) 10) Prof. Dr. Sulaiman Hj. Hasan (UTHM) 11) Prof. Dr. Zuraidah Mohd. Zain (UniMAP) 12) Prof. Dr. Horizon Gitano (USM) 13) Prof. Dr. K.V Sharma (UMP) 14) Prof. Dr. Shahrani Anuar (UMP) 15) Assoc. Prof. Dr. Abd Rashid Abd. Aziz (UTP) 16) Assoc. Prof. Dr. Aidy Ali (UPM) 17) Assoc. Prof. Dr. Saidur Rahman (UM) 18) Assoc. Prof. Dr. Md Abdul Maleque (UIA) Organizing Committee Chairman: Prof. Dr. Hj. Rosli Abu Bakar Co-Chair: Prof. Dr. Zahari Taha Co-Chair: Prof. Ir. Dr. Jailani Salihon Secretary: Dr. Rizalman Mamat Committee on Keynote Speaker 1) Kumaran Kadirgama (Chair) 2) Prof. Dr. K.V. Sharma 3) Haji Amirruddin Abdul Kadir 4) Miminorazeansuhaila Loman 5) Mohd Akramin Mohd Romlay Technical Committee (Peer Review & Proceedings) 1) Dr. Abdul Adam Abdullah (Chair) 2) Dr. Ahmad Razlan Yusoff 3) Mohd Yusof Taib 4) Dr. Md. Mustafizur Rahman 5) Dr. Hjh. Yusnita Rahayu 6) Dr. Gigih Priyandoko 7) Dr. Agung Sudrajad 8) Muhammad Hatifi Mansor 9) Mohd Fadzil Abdul Rahim Technical Committee (Panels & Session Chairs) 1) Dr. Mahadzir Ishak (Chair) 2) Prof. Dr. Shahrani Anuar 3) Dr. Maisara Mohyeldin Gasim Mohamed 4) Muhammad Ammar Nik Mu'tasim 5) Ahmad Basirul Subha bin Alias Technical Committee (Journal Publication) 1) Dr. Ahmad Razlan bin Yusoff (Chair) 2) Mohd Yusof Taib 3) Dr. Mahadzir Ishak 4) Dr. Abdul Adam Abdullah 5) Hj. Amirruddin Abdul Kadir 6) Hadi Abdul Salaam Bureau of Publicity & Website 1) Dr. Muhamad Arifpin Mansor (Chair) 2) Amir Abdul Razak 3) Idris Mat Sahat 4) Prof. Dr. Hj. Rosli Abu Bakar 5) Muhamad Zuhairi Sulaiman 6) Dr. Sugeng Ariyono 7) Asnul Hadi Ahmad 8) Mohd Tarmizy Che Kar 9) Mohd Padzly Radzi Bureau of Special Task & Poster 1) Lee Giok Chui (Chair) 2) Mohd Fadzil Abdul Rahim 3) Che Ku Eddy Nizwan 4) Hazami Che Hussain 5) Mohd Fazli Ismail 6) Mahdhir Mohd Yusof 7) Mohd Padzly Radzi 8) Rahimah Che Ramli Secretariats 1) Ir. Ahmad Rasdan Ismail (Chair) 2) Mohd Shahri Mohd Akhir 3) Luqman Hakim Ahmad Shah 4) Juliawati Alias 5) Nurazima Ismail 6) Mohamad Faizal Mohamed Zahri 7) Raja Allen Jordan Izzuddin Shah 8) Rosidah Mohd Norsat 9) Norshalawati Mat Yusof 10) Zainab Daud 11) Nur Sufiah Jamaludin 12) Azslinda Ibrahim 13) Nurul Azreen Zainal Abidin 14) Nurul Ashikin Mohd Khalil 15) Mohd Zaki Mohd Ali

  19. Army-UNL Center for Trauma Mechanics

    DTIC Science & Technology

    2011-03-07

    Jung Yul Lim, Dr. Joseph A. Turner, Dr. Florin Bobaru, Dr. Mehrdad Negahban University of Nebraska Research Grants & Contracts 303 Administration...none) 1. Matthew Nienaber,* Jeong Soon Lee,* Ruqiang Feng, Jung Yul Lim. Impulsive pressurization of neuronal cells for traumatic brain injury study...Toronto, Canada, October 16-18, 2010. 11. Jeong Soon Lee, Matthew Nienaber, Ruqiang Feng, Jung Yul Lim. Impulsive pressurization of neuronal cells for

  20. Conference report on the Indo Global Summit on Head and Neck Oncology (IGSHNO 2017-BMCON-IV), 24–26 February 2017, Jaipur, India

    PubMed Central

    Soni, Tej Prakash; Gupta, Anil K; Sharma, Lalit M; Singhal, Pawan; Yadav, Dinesh; Bansal, Umesh

    2017-01-01

    ‘The multidisciplinary approach: expanding treatment horizons for head and neck cancer’ was the major theme of the Indo Global Summit on Head and Neck Oncology (IGSHNO 2017-BMCON-IV). The meeting, held in Jaipur (Rajasthan, India) from 24 to 26 February 2017, assembled 600 participants from India and worldwide. It was organised by the Bhagwan Mahaveer Cancer Hospital and Research Centre (BMCHRC), Jaipur. BMCHRC Jaipur is one of the largest superspeciality oncology research and treatment centres in north India. The vision of BMCHRC has been to foster collaboration between oncologists, encouraging dialogue in an open forum that improves the care and outcomes of patients with cancer using the latest advances in cancer treatment. IGSHNO 2017 was part of this aim and vision. The organising team, including Dr Anil Gupta (Organising Secretary), Dr Lalit Mohan Sharma (Organising Secretary), Dr Pawan Singhal (Chairperson, scientific programme), Dr Tej Prakash Soni (Treasurer, Organising Secretary, Radiotherapy workshop), Dr Umesh Bansal and Dr Dinesh Yadav (Joint Organising Secretary), Dr Anjum Khan (Organising Secretary, Palliative care workshop), Dr Gaurav Pal Singh (Organising Secretary, Dental and prosthodontics workshop) and Dr (Maj Gen) SC Pareek (Medical Director, BMCHRC, Jaipur, India) worked hard for the previous 6 months to make this conference a successful academic event. IGSHNO 2017, held over three days, is a chance for oncologists from different parts of India to come together and discuss ongoing research, recent announcements and introduce new developments in head and neck cancer. It consisted of 51 lectures, seven debates, 10 panel discussions, oral paper presentations, e-poster sessions, a quiz for postgraduate students, a live surgery workshop, a prosthodentics workshop for dentists, a radiotherapy contouring workshop for radiation oncologists, a pain and palliative care workshop and a meet the expert session—all focusing on the multidisciplinary treatment of head and neck cancer. Special highlights from IGSHNO 2017 included the radiotherapy contouring workshop, the live surgery workshop by internationally renowned head and neck oncosurgeons, the dental and prosthodontics workshop and the pain and palliative care workshop. PMID:28626489

  1. Conference report on the Indo Global Summit on Head and Neck Oncology (IGSHNO 2017-BMCON-IV), 24-26 February 2017, Jaipur, India.

    PubMed

    Soni, Tej Prakash; Gupta, Anil K; Sharma, Lalit M; Singhal, Pawan; Yadav, Dinesh; Bansal, Umesh

    2017-01-01

    'The multidisciplinary approach: expanding treatment horizons for head and neck cancer' was the major theme of the Indo Global Summit on Head and Neck Oncology (IGSHNO 2017-BMCON-IV). The meeting, held in Jaipur (Rajasthan, India) from 24 to 26 February 2017, assembled 600 participants from India and worldwide. It was organised by the Bhagwan Mahaveer Cancer Hospital and Research Centre (BMCHRC), Jaipur. BMCHRC Jaipur is one of the largest superspeciality oncology research and treatment centres in north India. The vision of BMCHRC has been to foster collaboration between oncologists, encouraging dialogue in an open forum that improves the care and outcomes of patients with cancer using the latest advances in cancer treatment. IGSHNO 2017 was part of this aim and vision. The organising team, including Dr Anil Gupta (Organising Secretary), Dr Lalit Mohan Sharma (Organising Secretary), Dr Pawan Singhal (Chairperson, scientific programme), Dr Tej Prakash Soni (Treasurer, Organising Secretary, Radiotherapy workshop), Dr Umesh Bansal and Dr Dinesh Yadav (Joint Organising Secretary), Dr Anjum Khan (Organising Secretary, Palliative care workshop), Dr Gaurav Pal Singh (Organising Secretary, Dental and prosthodontics workshop) and Dr (Maj Gen) SC Pareek (Medical Director, BMCHRC, Jaipur, India) worked hard for the previous 6 months to make this conference a successful academic event. IGSHNO 2017, held over three days, is a chance for oncologists from different parts of India to come together and discuss ongoing research, recent announcements and introduce new developments in head and neck cancer. It consisted of 51 lectures, seven debates, 10 panel discussions, oral paper presentations, e-poster sessions, a quiz for postgraduate students, a live surgery workshop, a prosthodentics workshop for dentists, a radiotherapy contouring workshop for radiation oncologists, a pain and palliative care workshop and a meet the expert session-all focusing on the multidisciplinary treatment of head and neck cancer. Special highlights from IGSHNO 2017 included the radiotherapy contouring workshop, the live surgery workshop by internationally renowned head and neck oncosurgeons, the dental and prosthodontics workshop and the pain and palliative care workshop.

  2. Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death.

    PubMed

    Milutinovic, Snezana; Kashyap, Arun K; Yanagi, Teruki; Wimer, Carina; Zhou, Sihong; O'Neil, Ryann; Kurtzman, Aaron L; Faynboym, Alexsandr; Xu, Li; Hannum, Charles H; Diaz, Paul W; Matsuzawa, Shu-ichi; Horowitz, Michael; Horowitz, Lawrence; Bhatt, Ramesh R; Reed, John C

    2016-01-01

    Death receptors of the TNF family are found on the surface of most cancer cells and their activation typically kills cancer cells through the stimulation of the extrinsic apoptotic pathway. The endogenous ligand for death receptors 4 and 5 (DR4 and DR5) is TNF-related apoptosis-inducing ligand, TRAIL (Apo2L). As most untransformed cells are not susceptible to TRAIL-induced apoptosis, death receptor activators have emerged as promising cancer therapeutic agents. One strategy to stimulate death receptors in cancer patients is to use soluble human recombinant TRAIL protein, but this agent has limitations of a short half-life and decoy receptor sequestration. Another strategy that attempted to evade decoy receptor sequestration and to provide improved pharmacokinetic properties was to generate DR4 or DR5 agonist antibodies. The resulting monoclonal agonist antibodies overcame the limitations of short half-life and avoided decoy receptor sequestration, but are limited by activating only one of the two death receptors. Here, we describe a DR4 and DR5 dual agonist produced using Surrobody technology that activates both DR4 and DR5 to induce apoptotic death of cancer cells in vitro and in vivo and also avoids decoy receptor sequestration. This fully human anti-DR4/DR5 Surrobody displays superior potency to DR4- and DR5-specific antibodies, even when combined with TRAIL-sensitizing proapoptotic agents. Moreover, cancer cells were less likely to acquire resistance to Surrobody than either anti-DR4 or anti-DR5 monospecific antibodies. Taken together, Surrobody shows promising preclinical proapoptotic activity against cancer cells, meriting further exploration of its potential as a novel cancer therapeutic agent. ©2015 American Association for Cancer Research.

  3. Application of Electronic Meeting Systems to Military Organizations

    DTIC Science & Technology

    1989-06-21

    June 1989. Bibliography 24. Gray, P., Vogel, D.R., Beauclair , R. "A Typology for Group Decision Support System Research," European Journal of Operations...3, 1984. 7. Beauclair , R.A., "An Experimental Study of the Effects of Specific GDSS Applica- tions on Small Group Decision Making," University of...Vogel, D.R., Beauclair , R. "A Typology for Group Decision Support System Research," European Journal of Operations Research, forthcoming 60. Grohowski

  4. Respiratory medicine and research at McGill University: A historical perspective

    PubMed Central

    Martin, James G; Schwartzman, Kevin

    2015-01-01

    The history of respiratory medicine and research at McGill University (Montreal, Quebec) is tightly linked with the growth of academic medicine within its teaching hospitals. Dr Jonathan Meakins, a McGill medical graduate, was recruited to the Royal Victoria Hospital in 1924; as McGill’s first full-time clinical professor and Physician-in-Chief at the Royal Victoria Hospital. His focus on respiratory medicine led to the publication of his first book, Respiratory Function in Disease, in 1925. Meakins moved clinical laboratories from the Department of Pathology and placed them within the hospital. As such, he was responsible for the development of hospital-based research. Dr Ronald Christie was recruited as a postdoctoral fellow by Meakins in the early 1930s. After his fellowship, he returned to Britain but came back to McGill from St Bartholomew’s Hospital (London, United Kingdom) to become Chair of the Department of Medicine in 1955; he occupied the post for 10 years. He published extensively on the mechanical properties of the lung in common diseases such as emphysema and heart failure. Dr David Bates was among Dr Christie’s notable recruits; Bates in turn, recruited Drs Maurice McGregor, Margaret Becklake, William Thurlbeck, Joseph Milic-Emili, Nicholas Anthonisen, Charles Bryan and Peter Macklem. Bates published extensively in the area of respiratory physiology and, with Macklem and Christie, coauthored the book Respiratory Function in Disease, which integrated physiology into the analysis of disease. Dr JA Peter Paré joined the attending staff of the Royal Victoria Hospital and the Royal Edward Laurentian Hospital in 1949. A consummate clinician and teacher, he worked closely with Dr Robert Fraser, the Chair of Radiology, to write the reference text Diagnosis of Diseases of the Chest. This was a sentinel contribution in its focus on radiographic findings as the foundation for a systematic approach to diagnosis, and the correlation of these findings with pathological and clinical observations. Dr Margaret Becklake immigrated to Montreal from South Africa in 1957. Her research focused on occupational lung disease. She established the respiratory epidemiology research unit at McGill. She was renowned for her insistence on the importance of a clearly stated, relevant research question and for her clarity and insight. Dr William Thurlbeck, another South African, had developed an interest in emphysema and chronic bronchitis and applied a structure-function approach in collaboration with Peter Macklem and other respirologists. As chief of the Royal Victoria autopsy service, he used pathological specimens to develop a semiquantitative grading system of gross emphysema severity. He promoted the use of morphometry to quantify structural abnormalities. Dr James Hogg studied the functional consequences of pathological processes for lung function during his PhD studies under the joint supervision of Drs Macklem and Thurlbeck. His contributions to understanding the structural basis for chronic obstructive pulmonary disease (COPD) are numerous, reflecting his transdisciplinary knowledge of respiratory pathology and physiology. He trained other outstanding investigators such as Peter Paré Jr, with whom he founded the Pulmonary Research Laboratory in St Paul’s Hospital in Vancouver (British Columbia) in 1977. A signal event in the evolution of respiratory research at McGill was the construction of the Meakins-Christie Laboratories in 1972. These laboratories were directed by Dr Peter Macklem, a trainee of Dr Becklake’s. The research within the laboratory initially focused on respiratory mechanics, gas distribution within the lung and the contribution of airways of different sizes to the overall mechanical behaviour of the lungs. The effects of cigarette smoking on lung dysfunction, mechanisms of possible loss of lung elastic recoil in asthma and control of bronchomotor tone were all additional areas of active investigation. Dr Macklem pioneered the study of the physiological consequences of small airway pathology. Dr Joseph Milic-Emili succeeded Dr Macklem as director of the Meakins-Christie Laboratories in 1979. Milic-Emili was renowned for his work on ventilation distribution and the assessment of pleural pressure. He led the development of convenient tools for the assessment of respiratory drive. He clarified the physiological basis for carbon dioxide retention in patients with COPD placed on high inspired oxygen concentrations. Another area that captured many investigators’ attention in the 1980s was the notion of respiratory failure as a consequence of respiratory muscle fatigue. Dr Charalambos (‘Charis’) Roussos made seminal contributions in this field. These studies triggered a long-lasting interest in respiratory muscle training, in rehabilitation, and in noninvasive mechanical ventilation for acute and chronic respiratory failure. Dr Ludwig Engel obtained his PhD under the supervision of Peter Macklem and established himself in the area of ventilation distribution in health and in bronchoconstriction and the mechanics of breathing in asthma; he trained many investigators including one of the authors, Dr Jim Martin, who succeeded Milic-Emili as director of the Meakins Christie Laboratories from 1993 to 2008. Dr Martin developed small animal models of allergic asthma, and adopted a recruitment strategy that diversified the research programs at the Meakins Christie Laboratories. Dr Manuel Cosio built on earlier work with Macklem and Hogg in his development of key structure-function studies of COPD. He was instrumental in recruiting a new generation of young investigators with interests in sleep medicine and neuromuscular diseases. The 1970s and 1980s also witnessed the emergence of a topnotch respiratory division at the Montreal General Hospital, in large part reflecting the leadership of Dr Neil Colman, later a lead author of the revised Fraser and Paré textbook. At the Montreal General, areas of particular clinical strength and investigation included asthma, occupational and immunological lung diseases. In 1989, the Meakins Christie Laboratories relocated to its current site on Rue St Urbain, adjacent to the Montreal Chest Institute. Dr Qutayba Hamid, on faculty at the Brompton Hospital, joined the Meakins-Christie Labs in 1994. In addition to an outstanding career in the area of the immunopathology of human asthma, he broadened the array of techniques routinely applied at the labs and has ably led the Meakins-Christie Labs from 2008 to the present. The Meakins Christie Laboratories have had a remarkable track record that continues to this day. The basis for its enduring success is not immediately clear but it has almost certainly been linked to the balance of MD and PhD scientists that brought perspective and rigour. The diverse disciplines and research programs also facilitated adaptation to changing external research priorities. The late 1990s and the early 21st century also saw the flourishing of the Respiratory Epidemiology Unit, under the leadership of Drs Pierre Ernst, Dick Menzies and Jean Bourbeau. It moved from McGill University to the Montreal Chest Institute in 2004. This paved the way for expanded clinical and translational research programs in COPD, tuberculosis, asthma, respiratory sleep disorders and other pulmonary diseases. The faculty now comprises respiratory clinician-researchers and PhD scientists with expertise in epidemiological methods and biostatistics. Respiratory physiology and medicine at McGill benefitted from a strong start through the influence of Meakins and Christie, and a tight linkage between clinical observation and physiological research. The subsequent recruitment of talented and creative faculty members with absolute dedication to academic medicine continued the legacy. No matter how significant the scientific contributions of the individuals themselves, their most important impact resulted from the training of a large cohort of other gifted physicians and graduate students. Some of these are further described in the accompanying full-length online article. PMID:25664457

  5. Introducing NASA's Solar System Exploration Research Virtual Institute

    NASA Astrophysics Data System (ADS)

    Pendleton, Yvonne

    The Solar System Exploration Research Virtual Institute (SSERVI) is focused on the Moon, near Earth asteroids, and the moons of Mars. Comprised of competitively selected teams across the U.S., a growing number of international partnerships around the world, and a small central office located at NASA Ames Research Center, the institute advances collaborative research to bridge science and exploration goals. As a virtual institute, SSERVI brings unique skills and collaborative technologies for enhancing collaborative research between geographically disparate teams. SSERVI is jointly funded through the NASA Science Mission Directorate and the NASA Human Exploration and Operations Mission Directorate. Current U.S. teams include: Dr. Jennifer L. Heldmann, NASA Ames Research Center, Moffett Field, CA; Dr. William Farrell, NASA Goddard Space Flight Center, Greenbelt, MD; Prof. Carlé Pieters, Brown University, Providence, RI; Prof. Daniel Britt, University of Central Florida, Orlando, FL; Prof. Timothy Glotch, Stony Brook University, Stony Brook, NY; Dr. Mihaly Horanyi, University of Colorado, Boulder, CO; Dr. Ben Bussey, Johns Hopkins Univ. Applied Physics Laboratory, Laurel, MD; Dr. David A. Kring, Lunar and Planetary Institute, Houston, TX; and Dr. William Bottke, Southwest Research Institute, Boulder, CO. Interested in becoming part of SSERVI? SSERVI Cooperative Agreement Notice (CAN) awards are staggered every 2.5-3yrs, with award periods of five-years per team. SSERVI encourages those who wish to join the institute in the future to engage current teams and international partners regarding potential collaboration, and to participate in focus groups or current team activities now. Joining hand in hand with international partners is a winning strategy for raising the tide of Solar System science around the world. Non-U.S. science organizations can propose to become either Associate or Affiliate members on a no-exchange-of-funds basis. Current international partners include: Canada, Germany, Israel, Netherlands, Saudi Arabia, South Korea, and the United Kingdom. Discussions are ongoing to bring several more partners into the fold. These partnerships have impacted lunar science in a number of ways, resulting in such efforts and groups as the Pan-European Lunar Science Consortium and the Canadian Sudbury Field School. For more information visit sservi.nasa.gov

  6. NASA Graduate Student Researchers Program (GSRP)

    NASA Technical Reports Server (NTRS)

    Freeman, Frederick G.

    1998-01-01

    The primary area of research that Dr. Prinzel conducted was concerned with the effects of automation on the ability to perform various tasks which simulated those performed in an airplane cockpit. While automation is generally considered to be a positive addition to the cockpit, it also has some negative effects. The primary negative effect is related to the decrease in the number of tasks the pilot needs to perform. Having less to do can actually result in a decreased ability to be aware of and react to ongoing events, some of which may be critical to flight operations. The research was concerned with the ability of adaptive automation using psychophysiological measures, specifically brain waves (i.e. EEG), to control the degree to which tasks are automated as a function of the subject's level of alertness. Dr. Prinzel conducted and participated in the running of a number of experiments that examined adaptive automation in conjunction with the MultiAttribute Task Battery. Since there has been very little research conducted in this area, experiments needed to be conducted which established basic parameters for future research. The experiments that Dr. Prinzel was involved with examined the optimum number and location of electrode sites for recording EEG, the types of tasks which could readily be automated, the number of tasks which could be controlled by the adaptive automation system, and various EEG recording parameters which affect system functioning. A secondary area in which Dr. Prinzel conducted research concerned performance on vigiliance tasks. This research, while not initially directly related to adaptive automation, does have implication for such systems. Vigilance requires long term monitoring which often leads to the kind of negative effects seen when automation is introduced into a work environment. A third area of research in which Dr. Prinzel conducted research was concerned with gender differences in cognitive functioning and how that related to strategies for performing various tasks.

  7. Selected Publications by the NCI Director

    Cancer.gov

    Dr. Norman Sharpless's written work on cancer research appears in many leading scientific journals, as well as a variety of other publications. This page lists some of the articles published by Dr. Sharpless since becoming NCI director.

  8. Our Universe

    NASA Astrophysics Data System (ADS)

    Stern, Alan

    2001-03-01

    The Universe in which we live is unimaginably vast and ancient, with countless star systems, galaxies, and extraordinary phenomena such as black holes, dark matter, and gamma ray bursts. What phenomena remain mysteries, even to seasoned scientists? Our Universe is a fascinating collection of essays by some of the world's foremost astrophysicists. Some are theorists, some computational modelers, some observers, but all offer their insights into the most cutting-edge, difficult, and curious aspects of astrophysics. Compiled, the essays describe more than the latest techniques and findings. Each of the ten contributors offers a more personal perspective on their work, revealing what motivates them and how their careers and lives have been shaped by their desire to understand our universe. S. Alan Stern is Director of the Department of Space Studies at Southwest Research Institute in Boulder, Colorado. He is a planetary scientist and astrophysicist with both observational and theoretical interests. Stern is an avid pilot and a principal investigator in NASA's planetary research program, and he was selected to be a NASA space shuttle mission specialist finalist. He is the author of more than 100 papers and popular articles. His most recent book is Pluto & Charon (Wiley, 1997). Contributors: Dr. John Huchra, Harvard University Dr. Esther Hu, University of Hawaii, Honolulu Dr. John Mather, NASA Goddard Space Flight Center Dr. Nick Gnedin, University of Colorado, Boulder Dr. Doug Richstone, University of Michigan, Ann Arbor Dr. Bohdan Paczynski, Princeton University, NJ Dr. Megan Donahue, Space Telescope Science Institute, Baltimore, MD Dr. Jerry Ostriker, Princeton University, New Jersey G. Bothun, University of Oregon, Eugene

  9. Savannah River Ecology Laboratory. Annual technical progress report of ecological research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, M.H.

    1996-07-31

    The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA). The overall mission of the Laboratory is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under a contract with the U.S. Department of Energy (DOE) at the Savannah River Site (SRS) near Aiken, South Carolina. Significant accomplishments were made during the past year in the areas of research, education and service. The Laboratory`s research mission was fulfilled with the publication of two books and 143 journal articles andmore » book chapters by faculty, technical and students, and visiting scientists. An additional three books and about 80 journal articles currently are in press. Faculty, technician and students presented 193 lectures, scientific presentations, and posters to colleges and universities, including minority institutions. Dr. J Vaun McArthur organized and conducted the Third Annual SREL Symposium on the Environment: New Concepts in Strewn Ecology: An Integrative Approach. Dr. Michael Newman conducted a 5-day course titled Quantitative Methods in Ecotoxicology, and Dr. Brian Teppen of The Advanced Analytical Center for Environmental Sciences (AACES) taught a 3-day short course titled Introduction to Molecular Modeling of Environmental Systems. Dr. I. Lehr Brisbin co-hosted a meeting of the Crocodile Special Interest Group. Dr. Rebecca Sharitz attended four symposia in Japan during May and June 1996 and conducted meetings of the Executive Committee and Board of the International Association for Ecology (ENTECOL).« less

  10. Screening for depression with Centre for Epidemiological Studies Depression Scale Revised and its implication for consultation-liaison psychiatry practice among cancer subjects: a perspective from a developing country.

    PubMed

    Olagunju, Andrew T; Aina, Olatunji F; Fadipe, Babatunde

    2013-08-01

    Co-morbidity of depressive symptomatology is a common indication for use of mental health services in oncology. In this regard, screening instruments are useful for prompt identification of mental disorders in cancer. This study is set to evaluate the diagnostic validity of Centre for Epidemiological Studies Depression Scale Revised (CES-DR) for depression screening in cancer. The CES-DR and the Schedule for Clinical Assessment in Neuropsychiatry (SCAN) were administered by the researchers on 200 attendees of a Nigerian hospital with histological diagnoses of cancer. Subsequently, the diagnostic validity of CES-DR was compared with SCAN. Ninety-eight (49.0%) participants had significant depressive symptomatology (CES-DR scores of ≥ 16) as against the diagnosis of depression in 55 (27.5%) participants following SCAN interview. Furthermore, of these 55 (27.5%) depressed participants, two (3.6%) participants had CES-DR scores <16 (non-cases). The Cronbach's alpha reliability of CES-DR was 0.86, and sensitivity and specificity of CES-DR were 96.4% and 68.7%, respectively, whereas positive and negative predictive values of CES-DR were found to be 0.54 and 0.98, respectively, in this study. The average administration time of CES-DR was 6 (± 2) min, and an inter-rater reliability of 93.7% was observed. The CES-DR was found in this study to be a useful tool for screening for depression in cancer but with diagnostic limitation when compared with SCAN. The development as well as popularization of screening instrument(s) with improved diagnostic and administration property for prompt identification of mental disorders to improve consultation-liaison psychiatry services in cancer care is recommended. Furthermore, replication of similar research is warranted. Copyright © 2012 John Wiley & Sons, Ltd.

  11. MISSION AND COMMUNITY: THE AIR FORCE SOLUTION TO FUNDING BOTH

    DTIC Science & Technology

    2016-10-10

    1954-2014 (Reprinted from David Coleman research outlining military personnel numbers) Budget- Based Strategy How installations are shaped, sized...Jensen A Research Report Submitted to the Faculty In Partial Fulfillment of the Graduation Requirements Advisors: Dr. Marcia Ledlow and Dr. Brett...Morris Maxwell Air Force Base , Alabama October 2016 DISTRIBUTION A. Approved for public release: distribution unlimited. i Disclaimer The

  12. Microgravity

    NASA Image and Video Library

    1998-09-30

    Dr. Jan Rogers (left) and Larry Savage (foreground) of the Science Directorate at NASA's Marshall Space Flight Center (MSFC) are joined by Dr. Richard Weber (center) and April Hixon of Containerless Research Inc. of Evanston, Ill., in conducting an experiment run of the Electrostatic Levitator (ESL) using insulating materials. Materials researchers use unique capabilities of the facility to levitate and study the properties of various materials important in manufacturing processes.

  13. Immunology in Pittsburgh.

    PubMed

    Finn, Olivera J; Salter, Russell D

    2006-01-01

    The University of Pittsburgh School of Medicine has a long tradition of excellence in immunology research and training. Faculty, students, and postdoctoral fellows walk through hallways that are pictorial reminders of the days when Dr. Jonas Salk worked here to develop the polio vaccine, or when Dr. Niels Jerne chaired the Microbiology Department and worked on perfecting the Jerne Plaque Assay for antibody-producing cells. Colleagues and postdoctoral fellows of Professor Salk are still on the faculty of the University of Pittsburgh Medical School as are graduate students of Professor Jerne. A modern research building, the 17 story high Biomedical Science Tower, is a vivid reminder of the day when Dr. Thomas Starzl arrived in Pittsburgh and started building the most prominent solid-organ-transplant program in the world. The immunology research that developed around the problem of graft rejection and tolerance induction trained numerous outstanding students and fellows. Almost 20 yr ago, the University of Pittsburgh founded the University of Pittsburgh Cancer Institute (UPCI) with the renowned immunologist Dr. Ronald Herberman at its helm. This started a number of new research initiatives in cancer immunology and immunotherapy. A large number of outstanding young investigators, as well as several well-established tumor immunologists, were recruited to Pittsburgh at that time.

  14. Stress Exposure, Food Intake, and Emotional State

    PubMed Central

    Ulrich-Lai, Yvonne M.; Fulton, Stephanie; Wilson, Mark; Petrovich, Gorica; Rinaman, Linda

    2016-01-01

    This manuscript summarizes the proceedings of the symposium entitled, “Stress, Palatable Food and Reward”, that was chaired by Drs. Linda Rinaman and Yvonne Ulrich-Lai at the 2014 Neurobiology of Stress Workshop held in Cincinnati, OH. This symposium comprised research presentations by four neuroscientists whose work focuses on the biological bases for complex interactions among stress, food intake and emotion. First, Dr. Ulrich-Lai describes her rodent research exploring mechanisms by which the rewarding properties of sweet palatable foods confer stress relief. Second, Dr. Stephanie Fulton discusses her work in which excessive, long-term intake of dietary lipids, as well as their subsequent withdrawal, promotes stress-related outcomes in mice. Third, Dr. Mark Wilson describes his group’s research examining the effects of social hierarchy-related stress on food intake and diet choice in group-housed female rhesus macaques, and compared the data from monkeys to results obtained in analogous work using rodents. Lastly, Dr. Gorica Petrovich discusses her research program that is aimed at defining cortical–amygdalar–hypothalamic circuitry responsible for curbing food intake during emotional threat (i.e., fear anticipation) in rats. Their collective results reveal the complexity of physiological and behavioral interactions that link stress, food intake and emotional state, and suggest new avenues of research to probe the impact of genetic, metabolic, social, experiential, and environmental factors. PMID:26303312

  15. Stress exposure, food intake and emotional state.

    PubMed

    Ulrich-Lai, Yvonne M; Fulton, Stephanie; Wilson, Mark; Petrovich, Gorica; Rinaman, Linda

    2015-01-01

    This manuscript summarizes the proceedings of the symposium entitled, "Stress, Palatable Food and Reward", that was chaired by Drs. Linda Rinaman and Yvonne Ulrich-Lai at the 2014 Neurobiology of Stress Workshop held in Cincinnati, OH. This symposium comprised research presentations by four neuroscientists whose work focuses on the biological bases for complex interactions among stress, food intake and emotion. First, Dr Ulrich-Lai describes her rodent research exploring mechanisms by which the rewarding properties of sweet palatable foods confer stress relief. Second, Dr Stephanie Fulton discusses her work in which excessive, long-term intake of dietary lipids, as well as their subsequent withdrawal, promotes stress-related outcomes in mice. Third, Dr Mark Wilson describes his group's research examining the effects of social hierarchy-related stress on food intake and diet choice in group-housed female rhesus macaques, and compared the data from monkeys to results obtained in analogous work using rodents. Finally, Dr Gorica Petrovich discusses her research program that is aimed at defining cortical-amygdalar-hypothalamic circuitry responsible for curbing food intake during emotional threat (i.e. fear anticipation) in rats. Their collective results reveal the complexity of physiological and behavioral interactions that link stress, food intake and emotional state, and suggest new avenues of research to probe the impact of genetic, metabolic, social, experiential and environmental factors on these interactions.

  16. Summary of ORSphere Critical and Reactor Physics Measurements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marshall, Margaret A.; Bess, John D.

    In the early 1970s Dr. John T. Mihalczo (team leader), J. J. Lynn, and J. R. Taylor performed experiments at the Oak Ridge Critical Experiments Facility (ORCEF) with highly enriched uranium (HEU) metal (called Oak Ridge Alloy or ORALLOY) to recreate GODIVA I results with greater accuracy than those performed at Los Alamos National Laboratory in the 1950s. The purpose of the Oak Ridge ORALLOY Sphere (ORSphere) experiments was to estimate the unreflected and unmoderated critical mass of an idealized sphere of uranium metal corrected to a density, purity, and enrichment such that it could be compared with the GODIVAmore » I experiments. This critical configuration has been evaluated. Preliminary results were presented at ND2013. Since then, the evaluation was finalized and judged to be an acceptable benchmark experiment for the International Criticality Safety Benchmark Experiment Project (ICSBEP). Additionally, reactor physics measurements were performed to determine surface button worths, central void worth, delayed neutron fraction, prompt neutron decay constant, fission density and neutron importance. These measurements have been evaluated and found to be acceptable experiments and are discussed in full detail in the International Handbook of Evaluated Reactor Physics Benchmark Experiments. The purpose of this paper is summary summarize all the critical and reactor physics measurements evaluations and, when possible, to compare them to GODIVA experiment results.« less

  17. 15 years on the Editorial Board of PEPTIDES.

    PubMed

    Debeljuk, Luciano

    2015-10-01

    In this article, part of an issue of PEPTIDES celebrating the many years of dedication of Dr. A.J. Kastin as Editor-in-Chief of the journal, I describe how I first met him and how our friendship and collaboration developed. In 1970 I joined Dr. A.V. Schally's team at the Endocrine and Polypeptide Laboratories of Tulane University and the V.A. Hospital and it was at that time that I met Dr. Kastin for the first time. In 1984 I joined Dr. Schally's team for the second time and I began publishing part of my research findings in PEPTIDES. Afterward many more results from the research work were also published in PEPTIDES. I became a member of the Editorial Board of the same journal in 1999. It was going to be a very interesting experience. Some of my observations as a reviewer for PEPTIDES are described in the present article. Finally, I expressed my warmest congratulations to Dr. A.J. Kastin for the outstanding job that he carried out as Editor-in-Chief of PEPTIDES. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. The Oviduct and Serous Cancer Risk Assessment

    DTIC Science & Technology

    2016-10-01

    Career development for Dr. Xian (collaborator in the first year). Dr. Xian has recently obtained a Teal award stemming in part from opportunities...created during this collaboration. 3) Career development for Brooke Howitt at BWH. Dr. Howitt is a young faculty member at BWH who was involved in...carcinogenesis. She is currently applying for funding to expand her protected time for ovarian cancer research. 4) Career development for visiting

  19. The South Carolina Collaborative Undergraduate HBCU Student Summer Training Program

    DTIC Science & Technology

    2014-03-01

    Trial Perceptions in a Predominantly African American Sample in South Carolina Ms. Jasmine Fox SC State University Dr. Victoria Findlay NIH/NCI...145 146 147 148 149 150 151 Jasmine Fox Mentor: Dr. Victoria Findlay Funding Source: NIH/NCI P20 South Carolina Cancer...Presentations and Honors GRE Status Graduate School Admission Ms. Jasmine Fox SC State University Mentor: Dr. Victoria Findlay Research Project: MiR

  20. W.E. Henry Symposium compendium: The importance of magnetism in physics and material science

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carwell, H.

    This compendium contains papers presented at the W. E. Henry Symposium, The Importance of Magnetism in Physics and Material Science. The one-day symposium was conducted to recognize the achievements of Dr. Warren Elliot Henry as educator, scientist, and inventor in a career spanning almost 70 years. Dr. Henry, who is 88 years old, attended the symposium. Nobel Laureate, Dr. Glenn Seaborg, a friend and colleague for over 40 years, attended the event and shared his personal reminiscences. Dr. Seaborg is Associate Director-At-Large at the Lawrence Berkeley National Laboratory. The Compendium begins with three papers which demonstrate the ongoing importance ofmore » magnetism in physics and material science. Other contributions cover the highlights of Dr. Henry`s career as a researcher, educator, and inventor. Colleagues and former students share insights on the impact of Dr. Henry`s research in the field of magnetism, low temperature physics, and solid state physics; his influence on students as an educator; and his character, intellect and ingenuity, and passion for learning and teaching. They share a glimpse of the environment and times that molded him as a man, and the circumstances under which he made his great achievements despite the many challenges he faced.« less

  1. Learning to REDUCE: A Reduced Electricity Consumption Prediction Ensemble

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aman, Saima; Chelmis, Charalampos; Prasanna, Viktor

    Utilities use Demand Response (DR) to balance supply and demand in the electric grid by involving customers in efforts to reduce electricity consumption during peak periods. To implement and adapt DR under dynamically changing conditions of the grid, reliable prediction of reduced consumption is critical. However, despite the wealth of research on electricity consumption prediction and DR being long in practice, the problem of reduced consumption prediction remains largely un-addressed. In this paper, we identify unique computational challenges associated with the prediction of reduced consumption and contrast this to that of normal consumption and DR baseline prediction.We propose a novelmore » ensemble model that leverages different sequences of daily electricity consumption on DR event days as well as contextual attributes for reduced consumption prediction. We demonstrate the success of our model on a large, real-world, high resolution dataset from a university microgrid comprising of over 950 DR events across a diverse set of 32 buildings. Our model achieves an average error of 13.5%, an 8.8% improvement over the baseline. Our work is particularly relevant for buildings where electricity consumption is not tied to strict schedules. Our results and insights should prove useful to the researchers and practitioners working in the sustainable energy domain.« less

  2. Illinois Institute of Technology Report: IITB52 Antifoamer for Alternative Salt Processes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lambert, D.P.

    2001-06-27

    The attached report is a summary of the work performed by Dr. Darsh Wasan, Dr. Alex Nikolov, and their researchers at the Illinois Institute of Technology (IIT) during FY01. IIT developed the IITB52 antifoam for SRTC in FY00 to minimize the foam produced during precipitation, washing and concentration of cesium and potassium tetraphenyl borate precipitate. The IITB52 antifoam has been very successful during continuous processing (prototypical of plant operation). However, there were several key issues where SRTC needed the experience and knowledge of IIT to resolve. As a result a subcontract was set up with Dr. Wasan and Dr. Alexmore » Nikolov during FY01. This subcontract requested IIT to perform the basic research necessary to understand the foaming mechanism and explain the effectiveness of the IITB52 antifoam agent in the Small Tank Tetraphenylborate Process (STTP).« less

  3. Medicinal Cannabis in California: An Interview with Igor Grant, MD.

    PubMed

    Piomelli, Daniele; Grant, Igor

    2016-01-01

    Dr. Igor Grant, MD, is distinguished professor and chair of psychiatry and director of the HIV Neurobehavioral Research Program and the Center for Medicinal Cannabis Research at the University of California, San Diego. Dr. Grant is a neuropsychiatrist who graduated from the University of British Columbia School of Medicine (1966), and received specialty training in psychiatry at the University of Pennsylvania (1967-1971), and additional training in neurology at the Institute of Neurology (1980-1981), London, U.K. Dr. Grant's academic interests focus on the effects of various diseases on brain and behavior, with an emphasis on translational studies in HIV, and drugs of abuse. He has contributed to ∼700 scholarly publications and is principal investigator of several NIH studies, including an NIDA P50 (Translational Methamphetamine AIDS Research Center-TMARC), and is codirector of the HIV Neurobehavioral Research Center (HNRC).

  4. Strengthening IAEA Safeguards for Research Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reid, Bruce D.; Anzelon, George A.; Budlong-Sylvester, Kory

    During their December 10-11, 2013, workshop in Grenoble France, which focused on the history and future of safeguarding research reactors, the United States, France and the United Kingdom (UK) agreed to conduct a joint study exploring ways to strengthen the IAEA’s safeguards approach for declared research reactors. This decision was prompted by concerns about: 1) historical cases of non-compliance involving misuse (including the use of non-nuclear materials for production of neutron generators for weapons) and diversion that were discovered, in many cases, long after the violations took place and as part of broader pattern of undeclared activities in half amore » dozen countries; 2) the fact that, under the Safeguards Criteria, the IAEA inspects some reactors (e.g., those with power levels under 25 MWt) less than once per year; 3) the long-standing precedent of States using heavy water research reactors (HWRR) to produce plutonium for weapons programs; 4) the use of HEU fuel in some research reactors; and 5) various technical characteristics common to some types of research reactors that could provide an opportunity for potential proliferators to misuse the facility or divert material with low probability of detection by the IAEA. In some research reactors it is difficult to detect diversion or undeclared irradiation. In addition, infrastructure associated with research reactors could pose a safeguards challenge. To strengthen the effectiveness of safeguards at the State level, this paper advocates that the IAEA consider ways to focus additional attention and broaden its safeguards toolbox for research reactors. This increase in focus on the research reactors could begin with the recognition that the research reactor (of any size) could be a common path element on a large number of technically plausible pathways that must be considered when performing acquisition pathway analysis (APA) for developing a State Level Approach (SLA) and Annual Implementation Plan (AIP). To broaden the IAEA safeguards toolbox, the study recommends that the Agency consider closing potential gaps in safeguards coverage by, among other things: 1) adapting its safeguards measures based on a case-by-case assessment; 2) using more frequent and expanded/enhanced mailbox declarations (ideally with remote transmission of the data to IAEA Headquarters in Vienna) coupled with short-notice or unannounced inspections; 3) putting more emphasis on the collection and analysis of environmental samples at hot cells and waste storage tanks; 4) taking Safeguards by Design into account for the construction of new research reactors and best practices for existing research reactors; 5) utilizing fully all legal authorities to enhance inspection access (including a strengthened and continuing DIV process); and 6) utilizing new approaches to improve auditing activities, verify reactor operating data history, and track/monitor the movement and storage of spent fuel.« less

  5. Evaluation of nuclear facility decommissioning projects. Summary report: North Carolina State University Research and Training Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Link, B.W.; Miller, R.L.

    1983-08-01

    This document summarizes information from the decommissioning of the NCSUR-3 (R-3), a 10 KWt university research and training reactor. The decommissioning data were placed in a computerized information retrieval/manipulation system which permits future utilization of this information in pre-decommissioning activities with other university reactors of similar design. The information is presented both in some detail in its computer output form and also as a manually assembled summarization which highlights the more significant aspects of the decommissioning project. Decommissioning data from a generic study, NUREG/CR 1756, Technology, Safety and Costs of Decommissioning Nuclear Research and Test Reactors, and the decommissioning ofmore » the Ames Laboratory Research Reactor (ALRR), a 5 MWt research reactor, is also included for comparison.« less

  6. Supply of enriched uranium for research reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mueller, H.

    1997-08-01

    Since the RERTR-meeting In Newport/USA in 1990 the author delivered a series of papers in connection with the fuel cycle for research reactors dealing with its front-end. In these papers the author underlined the need for unified specifications for enriched uranium metal suitable for the production of fuel elements and made proposals with regard to the re-use of in Europe reprocessed highly enriched uranium. With regard to the fuel cycle of research reactors the research reactor community was since 1989 more concentrating on the problems of its back-end since the USA stopped the acceptance of spent research reactor fuel onmore » December 31, 1988. Now, since it is apparent that these back-end problem have been solved by AEA`s ability to reprocess and the preparedness of the USA to again accept physically spent research reactor fuel the author is focusing with this paper again on the front-end of the fuel cycle on the question whether there is at all a safe supply of low and high enriched uranium for research reactors in the future.« less

  7. Metal Mesh Fabrication and Testing for Infrared Astronomy and ISO Science Programs; ISO GO Data Analysis and LWS Instrument Team Activities

    NASA Technical Reports Server (NTRS)

    Smith, Howard A.; Oliversen, Ronald J. (Technical Monitor)

    2001-01-01

    This research program addresses astrophysics research with the Infrared Space Observatory's Long Wavelength Spectrometer (ISO-LWS), including efforts to supply ISO-LWS with superior metal mesh filters. This grant has, over the years, enabled Dr. Smith in his role as a Co-Investigator on the satellite, the PI (Principal Investigator) on the Extragalactic Science Team, and a member of the Calibration and performance working groups. The emphasis of the budget in this proposal is in support of Dr. Smith's Infrared Space Observatory research. This program began (under a different grant number) while Dr. Smith was at the Smithsonian's National Air and Space Museum, and was transferred to SAO with a change in number. While Dr. Smith was a visiting Discipline Scientist at NASA HQ the program was in abeyance, but it has resumed in full since his return to SAO. The Infrared Space Observatory mission was launched in November, 1996, and since then has successfully completed its planned lifetime mission. Data are currently being calibrated to the 2% level.

  8. Latin America multidisciplinary research on heat shock proteins and cell stress: proceedings of the first conference of the Latin America Chapter of the Cell Stress Society International.

    PubMed

    Bausero, María A

    2015-09-01

    The First Conference of the Latin America Chapter of the Cell Stress Society International (CSSI) organized by CSSI was held in Montevideo, Uruguay, on March 11-14, 2014. The Latin America Chapter of the CSSI (LAC-CSSI) was established at the Workshop on the Molecular Biology of the Stress Response, Porto Alegre, Brazil, May 2012. The chapter's first meeting took place in the beautiful city of Montevideo and was chaired by the first (LAC-CSSI) elected president Professor María Bausero. Forty-two invited speakers presented their work to more than 100 scientists. The first day of the conference was dedicated to an introductory program for students, young investigators, and participants new to the field of molecular chaperones and the stress response. These seminars were held in the Pasteur Institute of Montevideo and the Faculty of Sciences of the University of the Republic. These institutions were carefully selected to give foreign participants a broad view of the diversity of students and institutions doing research in Uruguay, as well as an opportunity for direct interaction with our scientists and students. Invited speakers for the seminar series were Dr. Wolfgang Schumann, Dr. Cristina Bonorino, Dr. Antonio De Maio, Dr. Ian Brown, Dr. Rafael Radi, Dr. Daniel Ciocca, and Dr. Celia Quijano. The remaining days of the conference took place at the Sheraton Hotel in Montevideo, and the scientific sessions are discussed below.

  9. Developmental considerations for substance use interventions from middle school through college.

    PubMed

    D'Amico, Elizabeth J; Ellickson, Phyllis L; Wagner, Eric F; Turrisi, Rob; Fromme, Kim; Ghosh-Dastidar, Bonnie; Longshore, Douglas L; McCaffrey, Daniel F; Montgomery, Marilyn J; Schonlau, Matthias; Wright, Dale

    2005-03-01

    This article summarizes a symposium organized by Dr. Elizabeth D'Amico and presented at the 2004 Annual Meeting of the Research Society on Alcoholism in Vancouver, Canada. The four presentations illustrate the importance of creating substance use interventions that are developmentally appropriate for youth. They represent innovative approaches to working with preteens, teenagers, and young adults. Dr. D'Amico's paper describes her research on the development of a voluntary brief intervention targeting alcohol use among middle school students. Findings indicated that by using school and community input, she was able to obtain a diverse a sample of youth across grades, sex, ethnicity, and substance use status. Dr. Ellickson's paper describes her research on Project ALERT, a school-based prevention program for middle school youth. Her findings indicate that Project ALERT worked for students at all levels of risk (low, moderate, and high) and for all students combined. Dr. Wagner's Teen Intervention Project was a randomized clinical trial to test the efficacy of a standardized Student Assistance Program for treating middle and high school students with alcohol and other drug problems. The study provided a unique opportunity to begin to examine how development may impact response to an alcohol or other drug intervention. Dr. Turrisi's paper examined processes underlying the nature of the effects of a parent intervention on college student drinking tendencies. Findings suggested that the parent intervention seems to have its impact on student drinking by reducing the influence of negative communications and decreasing the susceptibility of influences from closest friends. Dr. Kim Fromme provided concluding remarks.

  10. Experiences in utilization of research reactors in Yugoslavia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Copic, M.; Gabrovsek, Z.; Pop-Jordanov, J.

    1971-06-15

    The nuclear institutes in Yugoslavia possess three research reactors. Since 1958, two heavy-water reactors have been in operation at the 'Boris Kidric' Institute, a zero-power reactor RB and a 6. 5-MW reactor RA. At the Jozef Stefan Institute, a 250-kW TRIGA Mark II reactor has been operating since 1966. All reactors are equipped with the necessary experimental facilities. The main activities based on these reactors are: (1) fundamental research in solid-state and nuclear physics; (2) R and D activities related to nuclear power program; and (3) radioisotope production. In fundamental physics, inelastic neutron scattering and diffraction phenomena are studied bymore » means of the neutron beam tubes and applied to investigations of the structures of solids and liquids. Valuable results are also obtained in n - γ reaction studies. Experiments connected with the fuel -element development program, owing to the characteristics of the existing reactors, are limited to determination of the fuel element parameters, to studies on the purity of uranium, and to a small number of capsule irradiations. All three reactors are also used for the verification of different methods applied in the analysis of power reactors, particularly concerning neutron flux distributions, the optimization of reactor core configurations and the shielding effects. An appreciable irradiation space in the reactors is reserved for isotope production. Fruitful international co-operation has been established in all these activities, on the basis of either bilateral or multilateral arrangements. The paper gives a critical analysis of the utilization of research reactors in a developing country such as Yugoslavia. The investments in and the operational costs of research reactors are compared with the benefits obtained in different areas of reactor application. The impact on the general scientific, technological and educational level in the country is also considered. In particular, an attempt is made ro envisage the role of research reactors in the promotion of nuclear power programs in relation to the size of the program, the competence of domestic industries and the degree of independence where fuel supply is concerned. (author)« less

  11. Dielectronic recombination experiments at the storage rings: From the present CSR to the future HIAF

    NASA Astrophysics Data System (ADS)

    Huang, Z. K.; Wen, W. Q.; Xu, X.; Wang, H. B.; Dou, L. J.; Chuai, X. Y.; Zhu, X. L.; Zhao, D. M.; Li, J.; Ma, X. M.; Mao, L. J.; Yang, J. C.; Yuan, Y. J.; Xu, W. Q.; Xie, L. Y.; Xu, T. H.; Yao, K.; Dong, C. Z.; Zhu, L. F.; Ma, X.

    2017-10-01

    Dielectronic recombination (DR) experiments of highly charged ions at the storage rings have been developed as a precision spectroscopic tool to investigate the atomic structure as well as nuclear properties of stable and unstable nuclei. The DR experiment on lithium-like argon ions was successfully performed at main Cooler Storage Ring (CSRm) at Heavy Ion Research Facility in Lanzhou (HIRFL) accelerator complex. The DR experiments on heavy highly charged ions and even radioactive ions are currently under preparation at the experimental Cooler Storage Ring (CSRe) at HIRFL. The current status of DR experiments at the CSRm and the preparation of the DR experiments at the CSRe are presented. In addition, an overview of DR experiments by employing an electron cooler and a separated ultra-cold electron target at the upcoming High Intensity heavy ion Accelerator Facility (HIAF) will be given.

  12. Qualitative Student Models,

    DTIC Science & Technology

    1986-05-01

    University of Leyden AFOSR Baltimore, MD 21204 Education Research Center Bol g Boerhaavelaan 2 asolling ADCDr. Davida Charney 2334 EN Leyden Washington, DC...Kotovsky Dr. Charles Lewis Washington, DC 20002Department of Psychology Faculteit Sociale Wetenschappen Dr. Kathleen McKeownCommunity College of

  13. Grantee Spotlight: Rafael E. Guerrero-Preston, Dr.P.H., M.P.H.

    Cancer.gov

    Dr. Rafael E. Guerrero-Preston, an NCI/CRCHD K01 grantee, presented findings from his research on epigenomic biomarkers to improve head and neck cancer early detection and clinical management, and reduce survival disparities.

  14. Dr. Michael DeBakey "is a magician of the heart…"

    MedlinePlus

    ... Dr. DeBakey with NLM's David Nash and admiring students from the Michael E. DeBakey High School for ... medical research as the means of discovering improved methods of diagnosis, treatment, prevention, and cure. As far ...

  15. Blog Posts by the NCI Director Dr. Norman Sharpless

    Cancer.gov

    NCI Director Dr. Norman Sharpless writes posts regularly for NCI's Cancer Currents Blog that highlight his vision for NCI, meetings with and partnerships in the cancer community, and strategic and scientific initiatives to advance cancer research and care.

  16. Medical Research Pays Off for All Americans

    MedlinePlus

    ... the "March of Dimes." It helped develop two vaccines. The first, by Dr. Jonas Salk at the University of Pittsburgh, in 1955, and the second, in 1962, by Dr. Albert Sabin, at the Cincinnati Children's Hospital Medical Center – have ...

  17. United States Air Force Summer Faculty Research Program (1984). Program Management Report.

    DTIC Science & Technology

    1984-12-01

    6 Two-Color Refractometry for Dr. John D. R. Bahng Astronomical Geodesy 7 Long Wavelength infrared Emissions Dr. James C. Baird from a Recomnining...hardware, and conducting the experiment. 4 114 , -. ., -. . . . . . . . - ... . . .. . . . . . . . . . . . . . . . . . . TWO-ODLOR REFRACTOMETRY FOR

  18. The Children's Inn at NIH - Three Stories | NIH MedlinePlus the Magazine

    MedlinePlus

    ... in the school environment." Dr. Brian Brooks—The Team Co-Leader Dr. Brian Brooks uses a puppet ... much experience with." He coordinates a multi-disciplinary team of researchers, geneticists, nurses, counselors, and patients' families— ...

  19. Grantee Spotlight: Dr. Meena Jaggi - Investigating Curcumin (Turmeric) as HPV Repressor for Native A

    Cancer.gov

    Dr. Meena Jaggi’s research, funded by an NCI/CRCHD U01 grant, involves the use of curcumin (commonly known as turmeric) to inhibit human papillomavirus (HPV) infection among Native American (NA) women.

  20. Solution Techniques for Large Eigenvalue Problems in Structural Dynamics.

    DTIC Science & Technology

    1979-06-01

    Pasadena, California 91109 Washington, D.C. 20553 Professor Paul M. Naghdi National Academy of Sciences University of California National Research...Engineering Washington, D.C. 20064 : S oProfessor Burt Paul University of Pennsylvania Dr. Samuel B. Batdorf Towns School of Civil and University of...Universities (Con’t) Dr. V. K. Varadan Professor V. H. Neubert Ohio State University Research Foundation Pennsylvania State University Department of

  1. Methods for Evaluating Mammography Imaging Techniques

    DTIC Science & Technology

    1999-06-01

    Distribution Unlimited 12b. DIS5TRIBUTION CODE 13. ABSTRACT (Maximum 200 words) This Department of Defense Breast Cancer Research Program Career...Development Award is enabling Dr. Rütter to develop bio’statistical methods for breast cancer research. Dr. Rutter is focusing on methods for...evaluating the accuracy of breast cancer screening. This four year program includes advanced training in the epidemiology of breast cancer , training in

  2. Corneal Protection for Burn Patients

    DTIC Science & Technology

    2012-07-01

    Massachusetts General Hospital (by Professor Kochevar’s group) and the US Army Institute for Surgical Research (USISR) (by Dr. Johnson s group...carried at the Massachusetts General Hospital (by Professor Kochevar’s group) and the US Army Institute for Surgical Research (USISR) (by Dr...inverted microscopy system. This OCT system utilized a 120 nm bandwidth superluminensent diode source centered at 855 nm to provide an axial

  3. Maniac Talk - Dr. Jack Kaye

    NASA Image and Video Library

    2014-07-23

    Jack Kaye Maniac Lecture, July 23, 2014 Dr. Jack Kaye, Associate Director for Research at NASA Headquarters presented a Maniac Talk entitled, "An Unlikely but Rewarding Journey--From Quantum Chemistry to Earth Science Research Program Leadership." Jack took stock of his 30+ years at NASA, noting the people, opportunities, lessons learned, and choices that helped him get to where he is today and accomplish what he have.

  4. Generalizing Automated Assessment of Small Unit Tactical Decision Making

    DTIC Science & Technology

    2013-12-01

    stottlerhenke.com, presnell@stottlerhenke.com James Lunsford Decisive-Point, LLC Kansas City, MO jim@decisive-point.com Marshell G. Cobb US Army...engineer for Electronic Arts and Stormfront Studios. Dr. Marshell G. Cobb. In his current position with the US Army Research Institute (ARI), Dr...Lunsford Decisive-Point, LLC Kansas City, MO jim@decisive-point.com Marshell G. Cobb US Army Research Institute Ft. Benning, GA

  5. Oversight hearings on P. L. 93-577, ERDA Plan and Program. Hearings before the Subcommittee on Energy Research, Development and Demonstration of the Committee on Science and Technology, U. S. House of Representatives, Ninety-Fourth Congress, Second Session

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1976-01-01

    The purpose of the hearings was to examine the comprehensive plan and program for dealing with energy that ERDA submitted to Congress on June 30, 1975. Included as an appendix to these hearings is the October 1975 report of the Office of Technology Assessment (OTA) entitled, ''An Analysis of the ERDA Plan and Program'' (for abstract of this report, see EAPA 2:79). Testifying on Jan. 22 was the director of OTA, Emilio Q. Daddario, and chairmen of various task groups that assisted in the ERDA analysis, namely: Dr. John Gibbons, Conservation; Dr. Paul Craig, Overview Panel; Dr. Alvin Weinberg, Nuclear;more » Dr. Stanford S. Penner, Environmental and Health; and Dr. Jerry Grey, Solar; also present, and participating in the question and answer portion was Lionel Johns, head of the energy projects and programs in OTA. Testifying at the Jan. 23 hearings were experts presenting environmental, scientific, and engineering viewpoints, namely: Dr. Donald McDonald, director of the environmental studies program at Dartmouth College; Dr. Reginald Vachon, Auburn University, representing the American Society of Mechanical Engineers; and Dr. Thomas Lee, General Electric Co., representing the Inst. of Electrical and Electronics Engineers. The final hearings on Jan. 29 included the testimony of Dr. Robert W. Fri, Deputy Administrator, ERDA, and that of each of five assistant administrators: Dr. John Teem, Solar, Geothermal, and Advanced Energy Systems; Dr. Austin Heller, Conservation; Dr. Richard W. Roberts, Nuclear Energy; Dr. Roger W. A. LeGassie, Planning and Analysis; and Dr. James Liverman, Environment and Safety. (LMT)« less

  6. Communication and Decision Making in Cancer Care: Setting Research Priorities for Decision Support/Patients’ Decision Aids

    PubMed Central

    Barnato, Amber E.; Llewellyn-Thomas, Hilary A.; Peters, Ellen M.; Siminoff, Laura; Collins, E. Dale; Barry, Michael J.

    2013-01-01

    The following is a summary report from a special symposium, entitled “Translating Research into Practice: Setting a Research Agenda for Clinical Decision Tools in Cancer Prevention, Early Detection, and Treatment”, that was held on October 23, 2005 in San Francisco at the Annual Meeting of the Society for Medical Decision Making (SMDM). The symposium was designed to answer the question: “What are the top two research priorities in the field of patients’ cancer-related decision aids?” After introductory remarks by Dr. Barry, each of four panelists–Drs. Hilary Llewellyn-Thomas, Ellen Peters, Laura Siminoff, and Dale Collins–addressed the question and provided their rationale during prepared remarks. The moderator, Dr. Michael Barry, then facilitated a discussion between the panelists, with input from the audience, to further explore and add to the various proposed research questions. Finally, Dr. Amber Barnato conducted a simple vote count (see Table 1) to prioritize the panelists’ and the audience’s recommendations. PMID:17873249

  7. Human radiation studies: Remembering the early years. Oral history of biochemist John Randolph Totter, Ph.D., January 23, 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-09-01

    This document is a transcript of an interview of Dr. John Randolph Tottler by representatives of the US DOE Office of Human Radiation Experiments. Dr. Tottler was selected for this interview because of his career with the Atomic Energy Commission Division of Biology and Medicine (DBM), particularly as its director from 1967 to 1972. After a short biographical sketch Dr. Tottler discusses his remembrances on a wide range topics including nucleic acid and leukemia research at Oak Ridge, AEC biochemistry training in South America, DBM`s research focus on radiation effects, early leadership of DBM, relations with the US Public Healthmore » Service, controversies on low-level radiation, iodine from fallout, on John Gofman, and Project Plowshare, funding for AEC Research Programs and for international research, testicular irradiation of prisoners in Washington State and Oregon, Plutonium injections, ethics of government radiation research, and opinions of public misperceptions about radiation and cancer.« less

  8. Digital Tools for Cancer Prevention: Extending Reach and Engagement

    Cancer.gov

    Judith (Jodi) Prochaska, PhD, MPH, is Associate Professor of Medicine with the Stanford Prevention Research Center and a member of the Stanford Cancer Institute. Dr. Prochaska is a Principal Investigator on multiple research awards from the National Institutes of Health and the State of California Tobacco-Related Disease Research Program. Her research program is leveraging technology (e.g., web, text, social media) to bring tobacco cessation treatment into novel settings and to populations with high smoking prevalence. With attention to medical education and clinical practice, Dr. Prochaska has disseminated tobacco treatment curricula as part of Rx for Change (http://rxforchange.ucsf.edu). She has authored 175 peer-reviewed publications, serves on the Editorial Board of JAMA Internal Medicine, and is on the advisory board for Optum’s Quit for Life Tobacco Quitline. Dr. Prochaska is President of the Society for Research on Nicotine and Tobacco (SRNT), the international scientific society aimed at stimulating the generation and dissemination of new knowledge concerning nicotine and tobacco from bench to bedside and through to health policy.

  9. Application of Regional Arrays in Seismic Verification Research

    DTIC Science & Technology

    1990-08-31

    Hill, MA 02167 P.O. Box 1620 La Jolla, CA 92038-1620 Dr. Richard LaCoss Prof. William Menke MIT-Lincoln Laboratory L amront-Doherty -- dogical b ser t...LWH of Columbia University Hanscom AFB, MA 01731-5000 Palisades, NY 10964 3 Dr. Lorraine Wolf GLILWH Hanscom AFB, MA 01731-5000 Dr. William Wortman... William J. Best Prof. Robert W. Clayton 907 Westwood Drive Seismological Laboratory Vienna, VA 22180 Division of Geological & Planetary Sciences

  10. Regional Anesthesia and Valproate Sodium for the Prevention of Chronic Post Amputation Pain

    DTIC Science & Technology

    2016-10-01

    our Clinical Research Coordinator (CRC), Veda Byrd, unfortunately left Duke for family reasons. After her departure, we activated separate existing...was held with Mary McDuffie, Veda Byrd, Dr John Hsia, and Dr Thomas Buchheit. New data collection points and protocol language were discussed...Thomas Buchheit, Dr Thomas Van de Ven, Veda Byrd, Rachel Morales, Kelly Kiser, Nancy Kwon, Peter Bedocs, and Mary McDuffie. The advantages of whole

  11. Corneal Protection for Burn Patients

    DTIC Science & Technology

    2012-07-01

    for Surgical Research (USISR) (by Dr. Johnson’s group). This report covers results from Dr. Kochevar’s lab and Dr. Johnson is submitting an separate...system utilized a 120 nm bandwidth superluminensent diode source centered at 855 nm to provide an axial resolution of approximately 3 µm. A pair of...from a cw KTP laser , as reported previously. A weighed portion (~1 mg) was used to measure the collagenase degradation as described above and the

  12. Conference on the Neurobiology of Learning and Memory (3rd)

    DTIC Science & Technology

    1988-09-23

    TREATMENT IN PARADOXICAL SLEEP I. Portell-Cortes, DEPRIVATION PLATFORMS IN RATS . Norpdo-Bernal Area do Psicobiologia Dept. de Psicologia do la Salut Univ...of California Irvine, CA 92717 Irvine, CA 92717 Dr. Robert W. Doty Dr. David Easton Center for Brain Research School of Social Sciences Univ. of...Ignacio Morgado-Bernal Dr. Georges Moroz Area de Psicobiologia CNS Development Psicologia do la Salud CIBA-GEIGY Corp. Univ. Autonoma do Barcelona DEV

  13. Remarks on the physiological effects of defoliation on sugar maple and some impacts on syrup production

    Treesearch

    Philip M. Wargo

    1991-01-01

    The information I am going to present today is a conglomeration of some of the research on the effects of defoliation that has been done on sugar maple and oak. It involves work done by Drs. David Houston, Johnson Parker, Robert Gregory and me. Dr. Houston, a plant pathologist, and Dr. Parker, a plant physiologist, work with the USDA Forest Service in Hamden, Ct.; Dr....

  14. Improving causal inference with a doubly robust estimator that combines propensity score stratification and weighting.

    PubMed

    Linden, Ariel

    2017-08-01

    When a randomized controlled trial is not feasible, health researchers typically use observational data and rely on statistical methods to adjust for confounding when estimating treatment effects. These methods generally fall into 3 categories: (1) estimators based on a model for the outcome using conventional regression adjustment; (2) weighted estimators based on the propensity score (ie, a model for the treatment assignment); and (3) "doubly robust" (DR) estimators that model both the outcome and propensity score within the same framework. In this paper, we introduce a new DR estimator that utilizes marginal mean weighting through stratification (MMWS) as the basis for weighted adjustment. This estimator may prove more accurate than treatment effect estimators because MMWS has been shown to be more accurate than other models when the propensity score is misspecified. We therefore compare the performance of this new estimator to other commonly used treatment effects estimators. Monte Carlo simulation is used to compare the DR-MMWS estimator to regression adjustment, 2 weighted estimators based on the propensity score and 2 other DR methods. To assess performance under varied conditions, we vary the level of misspecification of the propensity score model as well as misspecify the outcome model. Overall, DR estimators generally outperform methods that model one or the other components (eg, propensity score or outcome). The DR-MMWS estimator outperforms all other estimators when both the propensity score and outcome models are misspecified and performs equally as well as other DR estimators when only the propensity score is misspecified. Health researchers should consider using DR-MMWS as the principal evaluation strategy in observational studies, as this estimator appears to outperform other estimators in its class. © 2017 John Wiley & Sons, Ltd.

  15. Slow Decomposition of Silicone Rubber.

    DTIC Science & Technology

    1982-09-01

    6i 0 20 0 0 -c CA soa ,~ I -- 00 N - C,,l I 21. DYN 6181 DISTRIBUTION LIST No. Cooies No. Cooies Dr. L.V. Schmidt 1 Or. F. Roberto 1 Assistant...Scientific Dr. A.L. Slafkosky 1 Research Scientific Advisor Directorate of Aerosoace Sciences Commandant of the Marine Corps Bolling Air Force Base Code...Research Research Code 413 Directorate of Chemical Sciences Arlington, VA 22217 Bolling Air Force Base Washington, D.C. 20332 M r . Da v id S i e g e lD r J

  16. Dr. Marco Marra: Pioneer and Visionary in Cancer Genomics Research | Office of Cancer Genomics

    Cancer.gov

    Dr. Marco Marra is a highly distinguished genomics and bioinformatics researcher. He is the Director of Canada’s Michael Smith Genome Sciences Centre at the BC Cancer Agency and holds a faculty position at the University of British Columbia. The Centre is a state-of-the-art sequencing facility in Vancouver, Canada, with a major focus on the study of cancers.  Many of their research projects are undertaken in collaborations with other Canadian and international institutions.

  17. Photon-Enhanced Electron Attachment Processes in Discharge-Opening Switches.

    DTIC Science & Technology

    1987-02-01

    period from 15 August 1983 through Auget 4 By: M. J. Rossi, H. Helm, and D. C. Lorents MAY 2 699 Prepared for: U.S. ARMY RESEARCH OFFICE P.O. Box 12211...A.. - .. Research Triangle Park, NC 27709 Attention: Dr. R. Gunther and Dr. D. Skatrud Contract No. DAAG29-83-K-01 13 SRI Project PYU-6261 Approved...iDENTIFICATION NUMBER ORGANIZATION (if applicable) J.S. Army Research office [________A -X e3 Ot-03 SC. ADDRESS (City, State. and ZIP Code) 10 SOURCE OF

  18. Light Visor

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Seasonal Affective Disorder is a form of depression brought on by reduced light. For some people, this can lead to clinical depression. NASA has conducted research in light therapy and employs it to help astronauts adjust internal rhythms during orbital flight. Dr. George Brainard, a medical researcher and NASA consultant, has developed a portable light therapy device, which is commercially available. The Light Visor allows continuous light therapy and can be powered by either batteries or electricity. Dr. Brainard continues to research various aspects of light therapy.

  19. Accident Source Terms for Pressurized Water Reactors with High-Burnup Cores Calculated using MELCOR 1.8.5.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gauntt, Randall O.; Goldmann, Andrew; Kalinich, Donald A.

    2016-12-01

    In this study, risk-significant pressurized-water reactor severe accident sequences are examined using MELCOR 1.8.5 to explore the range of fission product releases to the reactor containment building. Advances in the understanding of fission product release and transport behavior and severe accident progression are used to render best estimate analyses of selected accident sequences. Particular emphasis is placed on estimating the effects of high fuel burnup in contrast with low burnup on fission product releases to the containment. Supporting this emphasis, recent data available on fission product release from high-burnup (HBU) fuel from the French VERCOR project are used in thismore » study. The results of these analyses are treated as samples from a population of accident sequences in order to employ approximate order statistics characterization of the results. These trends and tendencies are then compared to the NUREG-1465 alternative source term prescription used today for regulatory applications. In general, greater differences are observed between the state-of-the-art calculations for either HBU or low-burnup (LBU) fuel and the NUREG-1465 containment release fractions than exist between HBU and LBU release fractions. Current analyses suggest that retention of fission products within the vessel and the reactor coolant system (RCS) are greater than contemplated in the NUREG-1465 prescription, and that, overall, release fractions to the containment are therefore lower across the board in the present analyses than suggested in NUREG-1465. The decreased volatility of Cs 2 MoO 4 compared to CsI or CsOH increases the predicted RCS retention of cesium, and as a result, cesium and iodine do not follow identical behaviors with respect to distribution among vessel, RCS, and containment. With respect to the regulatory alternative source term, greater differences are observed between the NUREG-1465 prescription and both HBU and LBU predictions than exist between HBU and LBU analyses. Additionally, current analyses suggest that the NUREG-1465 release fractions are conservative by about a factor of 2 in terms of release fractions and that release durations for in-vessel and late in-vessel release periods are in fact longer than the NUREG-1465 durations. It is currently planned that a subsequent report will further characterize these results using more refined statistical methods, permitting a more precise reformulation of the NUREG-1465 alternative source term for both LBU and HBU fuels, with the most important finding being that the NUREG-1465 formula appears to embody significant conservatism compared to current best-estimate analyses. ACKNOWLEDGEMENTS This work was supported by the United States Nuclear Regulatory Commission, Office of Nuclear Regulatory Research. The authors would like to thank Dr. Ian Gauld and Dr. Germina Ilas, of Oak Ridge National Laboratory, for their contributions to this work. In addition to development of core fission product inventory and decay heat information for use in MELCOR models, their insights related to fuel management practices and resulting effects on spatial distribution of fission products in the core was instrumental in completion of our work.« less

  20. Emigration dynamics in South Asia, IOM / UNFPA workshop, 2-3 September 1996, IOM headquarters, Geneva, Switzerland.

    PubMed

    Appleyard, R

    1996-01-01

    This paper describes the six research monographs that were presented at the Emigration Dynamic Workshops in South Asia in September 1996. Research reports were presented by Associate Professor Nasra Shah on an overview of emigration dynamics, Dr. Godfrey Gunatilleke on the role of networks and community structures in migration from Sri Lanka, Dr. Raisul Awal Mahmood on illegal migration from Bangladesh to Singapore, Kuala Lumpur, Bangkok, and Delhi due to desperate poverty, Dr. Farooq-i-Azam on high and low labor-sending migration districts in Pakistan, Dr. Mahendra K. Premi on the impact of internal Indian migration on international migration, and Dr. P.R. Gopinathan Nair on emigration from Kerala, India, to the Middle East. Representatives of South Asian governments discussed the implications of the research findings. Pakistan's representative urged cooperation and joint strategies among labor-sending countries. He cautioned that income and remittance estimates were unstable and unrealistic for inclusion in economic development plans. The Indian representative noted that, although Indian emigration is low, it is highly visible in the press. He agreed with the suggestion for greater cooperation between sending countries. The Bangladesh representative stated that the country needed to locate new markets for Bangladeshi emigrants, to guarantee the rights of emigrant workers, and to prevent trafficking in illegal migrant workers. Three major topics were discussed in the workshop session on the implementation of programs based on research findings. Workshop participants recommended updated information on migration trends, updated information on labor markets in receiving countries, formal and regular policy dialogue between sending countries, and promotion of continuing research by the International Organization on Migration.

  1. Fabrication and investigation of MnFe2O4/MWCNTs nanocomposite by hydrothermal technique and adsorption of cationic and anionic dyes

    NASA Astrophysics Data System (ADS)

    Kafshgari, Leila Asadi; Ghorbani, Mohsen; Azizi, Asghar

    2017-10-01

    In present study, MnFe2O4/MWCNT nanocomposite synthesized using the hydrothermal technique and has been used for removal of DR16 and Y40 dyes from aqueous solutions. The characteristics results of FTIR, XRD, FESEM and TEM indicated that the nanoadsorbent was successfully fabricated. Magnetic sensitivity results demonstrated that the nanoparticles with saturation magnetization (Ms) value of 8.93 emu g-1 would have a fast magnetic response. The performance of adsorption was investigated in a batch reactor employing parameters expected to affect the maximum adsorption capacity (qm) such as pH, contact time, initial dye concentration and temperature. The highest sorption capacities of DR16 and Y40 after 300 min at 328 K were found to be 607.79 mg/g and 280 mg/g at pH of 2 and 6, respectively. The adsorption behavior over the time was assessed through pseudo-first, pseudo-second and Weber-Morris intra particle diffusion models. It was found that the pseudo-second order model gave the best agreement to the experimental data. Adsorbate-adsorbent interactions as a function of temperature was evaluated by Langmuir, Freundlich, Temkin and Sips isotherm models from which Sips isotherm had the highest consistency with the experimental data. Thermodynamic parameters including ΔG°, ΔS° and ΔH° were determined over the temperature range of 298-328 K. The results revealed that the adsorption reaction of DR16 onto MnFe2O4/MWCNT was spontaneous and exothermic, whilst the sorption process of Y40 was spontaneous and endothermic. In addition, activation energy values implied that the removal process of DR16 and Y40 was physical in nature.

  2. Prostate Cancer Research Training in Health Disparities for Minority Undergraduates

    DTIC Science & Technology

    2015-06-01

    to school of dentistry , one is already in a graduate program, and one more is in the process of applying to dental school. Two of our interns now...L. Stewart  Cell Study  Thursday  May 23  Research Ethics   Dr. C. Freund   Introduction to  Biostatistics   Mr. Tan Ding   Digital Library   Ms. A...Training  Mr. Cedric Harville  Introduction to  Biostatistics   Dr. Vincent Agboto   Mentors’ Laboratory  Management of Cancer   Dr. L. Dent

  3. A Student of History: Perspectives on the Contributions of Estelle Brodman

    PubMed Central

    McClure, Lucretia W.

    2008-01-01

    Purpose: This paper is a reflection on the contributions of Estelle Brodman, PhD, as a historian through her publications and activities in the areas of medical history and history of medical librarianship. Methods: The publication record of Dr. Brodman was reviewed to identify the resources most relevant to the history of medicine and history of medical librarianship. Brief Description: As a historian, Dr. Brodman used manuscript collections to carry out original research. Publications resulting from her research and historical activities influenced her library colleagues to embrace history and brought new information to historians, scholars, and students. Dr. Brodman was the driving force behind the development of the Medical Library Association's oral history program. PMID:18654654

  4. Dr. John J. Stephens, Jr., metallurgist extraordinaire.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hosking, Floyd Michael

    The organizers of the Dr. John J. Stephens, Jr. Memorial Symposium: Deformation and Interfacial Phenomena in Advanced High-Temperature Materials are honoring the memory of Dr. Stephens and his many technical contributions that were accomplished over a relatively brief twenty year career. His research spanned the areas of creep and deformation of metals, dispersion-strengthened alloys and their properties, metal matrix composite materials, processing and properties of refractory metals, joining of ceramic-ceramic and metal-ceramic systems, active braze alloy development, and mechanical modeling of soldered and brazed assemblies. The purpose of this presentation is to highlight his research and engineering accomplishments, particularly duringmore » his professional career at Sandia National Laboratories in Albuquerque, NM.« less

  5. Dr. Kenneth Sudduth: A giant pioneering precision agriculture

    USDA-ARS?s Scientific Manuscript database

    Dr. Ken Sudduth is nationally and internationally recognized for his precision agriculture research and leadership, especially in the areas of soil sensing and assessment of spatial variability for site-specific management. His many noteworthy contributions include novel techniques and methodology f...

  6. Differential Dengue Tropism & Neutralization: Potential Mechanisms of Pathogenesis

    DTIC Science & Technology

    2006-01-04

    Dr. Guillermo Comach and Dr. Daria Camacho, Laboratorio Regional de Diagnostico e Investigacion del Dengue y otras Enfermedades Virales, Centro de... Enfermedades Virales, Centro de Investigaciones Biomedicas de la Universidad de Carabobo (LARDIDEV/BIOMED- UC), Maracay, Venezuela. 4Naval Medical Research

  7. Oxygen and Metastasis: A Conversation with Dr. Nick Restifo

    Cancer.gov

    Dr. Nick Restifo, a senior investigator in NCI’s Center for Cancer Research, discusses his recently published study finding that Oxygen, a molecule necessary for life, paradoxically aids cancer metastasis to the lung by impairing cancer-killing immune cells.

  8. Meet EPA Scientist Maureen R. Gwinn, M.S. Ph.D. DABT

    EPA Pesticide Factsheets

    EPA biologist Dr. Maureen Gwinn works on human health hazard assessments for the Agency's IRIS program. Dr. Gwinn currently serves as the Associate Program Director for Community Health in EPA's Sustainable and Healthy Communities national research program

  9. On Learning Maps

    DTIC Science & Technology

    1975-09-01

    Director, Office of Manpower Utilizatic Headquarters, Marine Corps (Code MPU ) MCB (Building 2009) Quantico, VA 22134 1 Dr. A.L. Slafkosky...National Defence HQ Ottawa, Canada K1A OK 2 1 Dr. Alma E. Lantz University of Denver Denver Research Institute Industrial Economics Division

  10. We are Not Hard-to-Reach: Community Competent Research to Address Racial Tobacco-Related Disparities

    Cancer.gov

    Dr. Webb Hooper is Associate Director for Cancer Disparities Research and Director of the Office of Cancer Disparities Research in the Case Comprehensive Cancer Center at Case Western Reserve University. She is also Professor of Oncology, Family Medicine & Community Health and Psychological Sciences. Dr. Webb Hooper is a licensed clinical health psychologist whose research interests are in chronic illness prevention and cancer risk behaviors, with an emphasis on minority health and racial/ethnic disparities. Much of her research focuses on tobacco use and weight management interventions, the development of culturally specific approaches, and understanding relationships between behavior change and race/ethnicity, cultural variables, modifiable risk factors, and the biological stress response. Dr. Webb Hooper has received international recognition for her contributions to nicotine and tobacco research, and is a leader in the field of cancer health disparities. Her research goal is to make a significant public health impact by reducing the prevalence of cancer and cancer health disparities in high-risk populations. Her long-term goal is to help eliminate disparities in chronic diseases. Dr. Webb Hooper’s research has been funded with over $9 million dollars by the National Cancer Institute (NCI), American Cancer Society (ACS), CVS Health Foundation, and the Florida Department of Health James and Esther King Biomedical Research Program.  In addition, Dr. Webb Hooper serves on committees for the NIH, several peer-reviewed journal editorial boards, is an Associate Editor of the Ethnicity & Disease Journal, and is Co-Chair of the Health Disparities Network of the Society for Research on Nicotine and Tobacco. WebEx When it's time, join the meeting. Meeting number (access code):  857 862 211 Meeting password:  Colloqu1@ Join by phone 1-650-479-3207 Call-in toll number (US/Canada) Can't join the meeting? IMPORTANT NOTICE:  Please note that this WebEx service allows audio and other information sent during the session to be recorded, which may be discoverable in a legal matter. By joining this session, you automatically consent to such recordings. If you do not consent to being recorded, discuss your concerns with the host or do not join the session.

  11. From Skeptic to Vital Partner in Massage Therapy Research: an Interview with Mark Hyman Rapaport, MD.

    PubMed

    Kennedy, Ann Blair

    2018-06-01

    Mark Hyman Rapaport, MD is a highly accomplished researcher, academician, and clinician. Dr. Rapaport has more than 180 publications, and his main research interests include biologic genesis of anxiety disorders, as well as immunity abnormalities and depression in mood disorders. His research investigating massage therapy has included study of inflammatory biomarkers, cancer related fatigue, and generalized anxiety disorder. He has created a successful partnership with the Atlanta School of Massage for the implementation of his research inquiry. Dr. Rapaport discusses with us a wide range of topics on massage therapy, including from where his inspiration for research comes.

  12. United States comparative costs and absenteeism of diabetic ophthalmic conditions.

    PubMed

    Brook, Richard A; Kleinman, Nathan L; Patel, Sunil; Smeeding, Jim E; Beren, Ian A; Turpcu, Adam

    2015-06-01

    This retrospective cohort study examined the impact of diabetic macular edema (DME), diabetic retinopathy (DR), or diabetes on annual health benefit costs and absenteeism in US employees. Claims data from 2001 to 2012 was extracted from the Human Capital Management Services Group Research Reference Database on annual direct/indirect health benefit costs and absences for employees aged ≥ 18 years. Employees with DME, DR, or diabetes were identified by International Classification of Diseases, Ninth Revision, Clinical Modification codes. Employees were divided into two groups, drivers or nondrivers, and examined in separate analyses. For drivers and nondrivers, the DME, DR, and diabetes cohorts were compared with their respective control groups (without diabetes). Two-part regression models controlled for demographics and job-related characteristics. A total of 39,702 driver and 426,549 nondriver employees were identified as having ≥ 1 year's continuous health plan enrollment. Direct medical costs for drivers with DME, DR, or diabetes were $6470, $8021, and $5102, respectively (>2.8 times higher and statistically significant compared with driver controls). Nondrivers with DME and DR incurred significantly higher sick leave and short-term disability costs compared with the nondrivers with diabetes and nondriver controls. In drivers with DME, the majority of days of absence were for short- and long-term disability (12.41 and 11.43 days, respectively). In drivers with DR, the majority of days of absence were for short-term disability (10.70 days). In nondrivers with DME and nondrivers with DR, the majority of days of absence were for sick leave (5.74 and 4.93 days, respectively) and short-term disability (5.08 and 4.93 days, respectively). DME and DR are associated with substantial direct medical cost and absenteeism in this real-world sample of medically insured employees. This research highlights the negative impact of DME and DR on annual costs and absenteeism and may assist employers in assessing the impact of these conditions on employees.

  13. Dr John McLennan MD (Aberdeen), FRCP (Lond) (1801-1874) and the Medical School of Bombay that failed.

    PubMed

    Pandya, Sunil K

    2017-01-01

    In 1826, Dr John McLennan was asked by Governor Mounstuart Elphinstone of Bombay to set up the first school to teach modern medicine to Indian citizens. He was expected to create textbooks on a variety of subjects in local languages and teach medicine to poorly educated students in their native tongues. Despite his valiant efforts, the school was deemed a failure and was abolished by the Government in 1832. Sir Robert Grant, appointed Governor of Bombay in 1835, analysed records pertaining to this medical school and concluded that the school failed since Dr McLennan was not provided the assistance he needed and as his suggestions for access to a hospital to teach medicine were not heeded. Dr McLennan provided able support to Dr Charles Morehead on his appointment as Principal and Professor of Medicine at the newly created Grant Medical College in Bombay in 1845. Dr Morehead dedicated his classic 'Clinical researches on diseases in India' to Dr McLennan. Dr McLennan headed the Board of Examiners created to assess the competence of the first batch of medical students emerging from this College. The system of evaluation set up by him remains admirable. Dr McLennan retired from service as Physician-General, full of honours.

  14. Therapeutic indications and other use-case-driven updates in the drug ontology: anti-malarials, anti-hypertensives, opioid analgesics, and a large term request.

    PubMed

    Hogan, William R; Hanna, Josh; Hicks, Amanda; Amirova, Samira; Bramblett, Baxter; Diller, Matthew; Enderez, Rodel; Modzelewski, Timothy; Vasconcelos, Mirela; Delcher, Chris

    2017-03-03

    The Drug Ontology (DrOn) is an OWL2-based representation of drug products and their ingredients, mechanisms of action, strengths, and dose forms. We originally created DrOn for use cases in comparative effectiveness research, primarily to identify historically complete sets of United States National Drug Codes (NDCs) that represent packaged drug products, by the ingredient(s), mechanism(s) of action, and so on contained in those products. Although we had designed DrOn from the outset to carefully distinguish those entities that have a therapeutic indication from those entities that have a molecular mechanism of action, we had not previously represented in DrOn any particular therapeutic indication. In this work, we add therapeutic indications for three research use cases: resistant hypertension, malaria, and opioid abuse research. We also added mechanisms of action for opioid analgesics and added 108 classes representing drug products in response to a large term request from the Program for Resistance, Immunology, Surveillance and Modeling of Malaria in Uganda (PRISM) project. The net result is a new version of DrOn, current to May 2016, that represents three major therapeutic classes of drugs and six new mechanisms of action. A therapeutic indication of a drug product is represented as a therapeutic function in DrOn. Adverse effects of drug products, as well as other therapeutic uses for which the drug product was not designed are dispositions. Our work provides a framework for representing additional therapeutic indications, adverse effects, and uses of drug products beyond their design. Our work also validated our past modeling decisions for specific types of mechanisms of action, namely effects mediated via receptor and/or enzyme binding. DrOn is available at: http://purl.obolibrary.org/obo/dron.owl . A smaller version without NDCs is available at: http://purl.obolibrary.org/obo/dron/dron-lite.owl.

  15. Origin of Marshall Space Flight Center (MSFC)

    NASA Image and Video Library

    1950-01-01

    Five pioneers pose with scale models of their missiles they created in the 1950s. From left to right: Dr. Ernst Stuhlinger, a member of the original German rocket team who directed the Research Projects Office, Army Ballistic Missile Agency (ABMA); Major General Holger Toftoy, who consolidated U.S. missile and rocketry development; Professor Herman Oberth, a rocket pioneer and Dr. von Braun's mentor; Dr. Wernher von Braun, Director, Development Operation Division, ABMA; and Dr. Robert Lusser, who served as assistant director for Reliability Engineering for ABMA. This photographis was taken February 1, 1956 by Hank Walker and appeared in February 27, 1956 issue of Life magazine.

  16. Li-Fraumeni syndrome: Discovery and future challenges - Joseph Fraumeni Symposium

    Cancer.gov

    In May 2014, NCI’s Division of Cancer Epidemiology and Genetics (DCEG) hosted Cancer Epidemiology: From Pedigrees to Populations, a scientific symposium honoring 50 years of visionary leadership by Dr. Joseph F. Fraumeni, Jr., the founding Director of DCEG. In this video, Dr. Stephen Chanock of NCI provides opening remarks. Dr. David Schottenfeld of the University of Michigan moderates a session on the search for cancer susceptibility genes. Dr. Louise Strong of University of Texas MD Anderson Cancer Center speaks about the discovery and future challenges of Li-Fraumeni syndrome research. For more information on this symposium, visit http://dceg.cancer.gov/news-events/Fraumeni-symposium-speakers.

  17. Five Pioneers with Scale Models of Their Missiles

    NASA Technical Reports Server (NTRS)

    1950-01-01

    Five pioneers pose with scale models of their missiles they created in the 1950s. From left to right: Dr. Ernst Stuhlinger, a member of the original German rocket team who directed the Research Projects Office, Army Ballistic Missile Agency (ABMA); Major General Holger Toftoy, who consolidated U.S. missile and rocketry development; Professor Herman Oberth, a rocket pioneer and Dr. von Braun's mentor; Dr. Wernher von Braun, Director, Development Operation Division, ABMA; and Dr. Robert Lusser, who served as assistant director for Reliability Engineering for ABMA. This photographis was taken February 1, 1956 by Hank Walker and appeared in February 27, 1956 issue of Life magazine.

  18. [What is the link between the sister of the "Titanic" and the history of medicine in Palestine?].

    PubMed

    Greenberg, Zalman

    2006-06-01

    On 21st November 1916, the Royal Navy Hospital ship 'Britannic' (the sister ship of the 'Titanic') was torpedoed near the island of Kea in the Aegean Sea. Captain Dr. John Cropper, aged 52, was one of 30 people who drowned of the 1100 on board. Dr. Cropper was born in 1864, at Guisborough, England. He obtained his medical degree from Cambridge University in 1891. After his marriage to Anne Ellen Walker in 1895, the Church Missionary Society sent him on a medical mission to Palestine. Dr. Cropper stayed in Palestine for about 10 years working in Acre, Nablus, Ramallah and Jerusalem. He published his experiences in 35 articles and letters in English medical periodicals, more than anyone else did in Palestine at that time. In those publications, he described various operations that he carried out and observations on infectious diseases, most of which were the first descriptions from that remote and unhealthy country. His prominent research was in the field of malaria - the most common and important disease in Palestine during that period. It was less than two years after Grassi's discovery of the role of Anopheles mosquitoes as the vector of human malaria that Dr. Cropper carried out surveys of larval and adult mosquitoes in correlation with malarial distribution in Palestine. Dr. Cropper was the first who routinely examined slides microscopically in Palestine and correctly diagnosed the type of malaria. Dr. Cropper was also the first in Palestine to suggest antimalarial measures aimed directly at the mosquito vector and paid attention to ecological aspects such as breeding places and the daily behavior of adult mosquitoes. Dr. Cropper noted the common antimalarial measurements of that time, such as covering of wells, planting of Eucalyptus trees to drain swamps and the routine use of quinine as a preventive medicine, but he wrote that those measures were not effective under the local conditions. He suggested that the only effective measures must be aimed against the larval mosquitoes and he recommended the use of a sulphur compound in order to destroy the larvae. Only many years later were those observations recognized as being correct. In our local public scientific memory, we remember early researchers such as Dr. Hillel Jaffe, Prof. Peter Muehlens, Prof. Israel Kligler, Prof. Gideon Mer, Dr. Zvi Saliternik and many others. Dr. Cropper preceded all of them. The comprehensive contributions of this English doctor to the medical research in Palestine should not be forgotten.

  19. GLOBAL CHANGE RESEARCH NEWS #16: POTENTIAL HEALTH IMPACTS OF CLIMATE VARIABILITY AND CHANGE FOR THE UNITED STATES, EXECUTIVE SUMMARY OF THE REPORT OF THE HEALTH SECTOR OF THE U.S. NATIONAL ASSESSMENT

    EPA Science Inventory

    The health sector assessment was sponsored by and conducted in partnership with EPA's Global Change Research Program. The report was produced by a Health Sector Work Group, co-chaired by Dr. Jonathan Patz (Johns Hopkins University) and Dr. Michael McGeehin (CDC), and this report ...

  20. NASA Mission: Encouraging the Pursuit of STEM Excellence

    NASA Technical Reports Server (NTRS)

    Lizcano, Maricela

    2015-01-01

    In this presentation, Dr. Maricela Lizcano will discuss her academic career path at UTPA that directed her to earn a PhD in Mechanical Engineering. Dr. Lizcano will also discuss her research area at NASA Glenn Research Center (NASA-GRC) and the various educational and career opportunities available at NASA. Her experiences, challenges, and goals will serve to both advise and encourage UTRGV students to pursue a STEM career.

  1. Bioremediation Approaches for Treating Low Concentrations of N-Nitrosodimethylamine in Groundwater

    DTIC Science & Technology

    2008-10-01

    OCTOBER 2008 Dr. Paul Hatzinger Shaw Environmental, Inc. Dr. Jalal Hawari Biotechnology Research Institute National Research Council, Canada...N-NITROSODIMETHYLAMINE (NDMA) IN GROUNDWATER W912-HQ-05-C-0041 NA ER-1456 NA NA Hatzinger, Paul B., Ph.D. Hawari, Jalal, Ph.D. Shaw Environmental, Inc...Leeson. 2007. US Environmental Protection Agency (USEPA) National Association of Remedial Project Managers (NARPM) Training Course. 2007. DoD’s

  2. Advanced Methods of Approximate Reasoning

    DTIC Science & Technology

    1990-11-30

    about Knowledge and Action. Technical Note 191, Menlo Park, California: SRI International. 1980 . 20 [26] N.J. Nilsson. Probabilistic logic. Artificial...reasoning. Artificial Intelligence, 13:81-132, 1980 . S[30 R. Reiter. On close world data bases. In H. Gallaire and J. Minker, editors, Logic and Data...specially grateful to Dr. Abraham Waksman of the Air Force Office of Scientific Research and Dr. David Hislop of the Army Research Office for their

  3. Basil A. Pruitt Jr. MD and the US Army Institute for Surgical Research: Five Decades of Science, Clinical Care, Mentorship, and Leadership.

    PubMed

    Stewart, Ronald M

    2017-08-24

    Over the past half century Dr. Basil A. Pruitt, Jr., a great citizen, surgeon, innovator, mentor and leader, transformed our world through his dogged commitment to science and service to humanity. Dr. Pruitt's contribution lives on in the work of the US Army Institute of Surgical Research and the surgeons, physicians and scientists he shaped and inspired.

  4. Case-based Influence in Conflict Management

    DTIC Science & Technology

    2014-10-31

    AFRL-OSR-VA-TR-2014-0337 CASE-BASED INFLUENCE IN CONFLICT MANAGEMENT Robert Axelrod ARTIS RESEARCH & RISK MODELING Final Report 10/31/2014...FA9550-10-1-0373 Dr. Robert Axelrod - PI Dr. Richard Davis- PD ARTIS Research & Risk Modeling ARTIS 5741 Canyon Ridge North Cave Creek, AZ 85331-9318...analysis of the timing of cyber conflict that quickly received attention from over 30 countries. 3 1 Axelrod , Final Report and Publications Final

  5. Air and Space Power Journal. Volume 29, Number 4. July-August 2015

    DTIC Science & Technology

    2015-08-01

    Afghanistan, and Pakistan. It is incredibly difficult to prevent these attacks when the most explicit strategies are reactive ex post facto military...Editor, Strategic Studies Quarterly Air Force Research Institute Dr. Grant T. Hammond USAF Center for Strategy and Technology Dr. Dale L. Hayden Air Force...of War Studies at King’s College London, researches nonproliferation, terrorism, and US security policy. He observes that deterrence strategies

  6. Annual Progress Report, January 1, 1969 through December 31, 1969.

    DTIC Science & Technology

    1970-02-01

    or extended. E. The Role of CAI in Curriculum Revision I The Intermediate Science Curriculum Study (ISCS)* (Dr. Ernest Burkman, i Director and Dr David...Educational Research, FSU. Henry T. Lippert , Ed.D., 1967, Education, University of Illinois, Research Associate in the CAI Center and Assistant...Walter Dick, and Henry T Lippert , Tech Report 3, Florida State University, Tallahassee, 1968 "A Systematic Investigation of Three Facets of Programmed

  7. Armed Forces Institute of Pathology Becomes CDC Registered Testing Site for Human Swine Influenza

    DTIC Science & Technology

    2010-01-01

    naval officer and pathologist during his nearly three decades of military service. Adrien Ravizee, research associate, is pipetting cells used to...grow influenza virus to new flasks and plates, so the cells can be infected with influenza virus as Dr. Sue Cross, virologist, left and Dr...Izadjoo said. “The collection can be used for validating improved diagnostic swine flu assays.” Dr. Sue Cross, a virologist, used cell cultures

  8. Frequency-Difference Source Localization and Blind Deconvolution in Shallow Ocean Environments

    DTIC Science & Technology

    2014-09-30

    investigations were recorded as part of the KAM11 experiment and were provided for this research effort by Dr. Heechun Song of Scripps Institution of...kHz ≤ f ≤ 20 kHz, could not. Based on this simulation success, suitable broadband experimental measurements were sought, and Dr. Song of SIO...PROJECTS This project currently uses acoustic array recordings of sounds that propagated through the ocean. In FY14, Dr. Heechun Song of SIO

  9. Preparation and Analysis of Samples for the Third Round Robin Verification Exercise

    DTIC Science & Technology

    1992-07-01

    Hooge 34 Lid instituuts Advies Raad PML Prof. dr. U.A. Th. Brinkman 35 Directeur van het Medisch Biologisch Laboratorium TNO Proft dr. W.R.F. Notten 36...1991 werd uitgevoerd, heeft het Prins Maurits Laboratorium TNO de monsters aangemaakt die bestonden uit rubber, verf en beton. Deze materialen, die...Maurits Laboratorium TNO Chemische Research Prof. dr. G. Dijksrra 10 HBur. NBC-DMKIJOMATIKIO In. A.A.M. Slagveer 11 Lid van de Contact Cominissie NBC

  10. Proceedings of Damping 󈨟, Held in San Diego, California on 13 - 15 February 1991. Volume 2

    DTIC Science & Technology

    1991-08-01

    Efficiency CBC* Dr. L. H. Sperling , J. J. Fay, and Dr. D. A. Thomas The Thermorheologically Complex Material CBD* Lt. Col. Ronald L. Bagley SESSION CC...Andrew S. Bicos. and J. S. Fechter The Need for Passive Damping in Feedback Controlled Flexible Struc- GBB tures Dr. Andreas von Flotow and D. W. Vos...Vibration Research, Southampton, England (R.C. Drew) Lehigh University, Bethlehem, Pennsylvania (L. Sperling ) MrS Corporation, Minneapolis, Minnesota

  11. Complex Information Coordination Performance: Differential Changes in Working Memory Contributions Following Training. Cognitive Components of Information Coordination

    DTIC Science & Technology

    1993-06-30

    UNIVERSITY DEPARTMENT OF PSYCHOLOGY EDUCATION BUILDING TALLAHASSEE FL 32306 W LAFAYETTE IN 47907 DR NEIL DORANS DR RODNEY COCKING EDUCATIONAL TESTING SERVICE...DR LORRAINE D EYDE PSYCHOLOGY DEPARTMENT US OFFICE OF PERSONNEL MGMT IOWA STATE UNIVERSITY OFFICE OF PERSONNEL RESEARCH AMES IA 50010 AND DEVELOP...judgments were performed under the added cognitive load of the coordination task. Method Subjects A total of eighty subjects were tested , with one

  12. Remedial Investigation of Contaminant Mobility at Naval Weapons Station, Concord, California.

    DTIC Science & Technology

    1986-01-01

    about benthic invertebrates and zooplankton pre- sented in Section 3.5.9.3 was obtained from a much more dispersed and incom- plete literature, which is...Encyclopedia of Marine Invertebrates , T. F. H. Publica- tions Inc., Ltd. White, H. H. 1979. "Effects of Dinoflagellate Bioluminescence on the Inges- tion Rates...Biologist, for the evaluation of wetland functional values; Dr. J. D. Lunz, Research Marine Biologist, Dr. D. R. Kendall, Aquatic Biologist, and Dr. T. J

  13. United States Air Force Summer Faculty Research Program, 1988. Program Technical Report. Volume 4

    DTIC Science & Technology

    1988-12-01

    Professor SDecialty: Gas Phase Ion-Molecule Chem. Dept. of Chemistry Assigned: Air Force Geophysics Lab. Louisiana State University Choppin Hall...For Lucid Dr. Darin DeForest 55 Pre-Sort Processor Phase Distortion Dr. Paul Dingman Evaluation 56 A PROLOG Natural Language Front End Dr. Hugh...analysis in the electron impact mode. The column used was 25m x 0.25am ID bonded phase FSOT capillary column (#952525 Alltech and Associates), coated with

  14. 77 FR 16868 - Quality Verification for Plate-Type Uranium-Aluminum Fuel Elements for Use in Research and Test...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... Fuel Elements for Use in Research and Test Reactors AGENCY: Nuclear Regulatory Commission. ACTION... Plate-Type Uranium-Aluminum Fuel Elements for Use in Research and Test Reactors.'' This guide describes... plate-type uranium-aluminum fuel elements used in research and test reactors (RTRs). DATES: Submit...

  15. NOAA Photo Library - Meet the Photographers/Dr. James P. McVey

    Science.gov Websites

    research cruises and expeditions as a diver and biologist which required him to learn the life histories artificial reef studies in Hawaiian waters. Dr. McVey has served on the World Aquaculture Society Board of

  16. Research into Queueing Network Theory.

    DTIC Science & Technology

    1977-09-01

    and Zeigler, B. (1975) "Equilibrium properties of arbitrarily interconnected queueing netowrks ," Tech. Report 75-4, Computer and Communication...Associate. The project was extremely fortunate to secure the services of Dr. Wendel. Dr. Wendel was a project member for one month in the summer of

  17. Interview: interview with P Jeffrey Conn. Interview by Hannah Coaker.

    PubMed

    Conn, P Jeffrey

    2013-09-01

    Dr Conn is the Lee E Limbird Professor of Pharmacology at Vanderbilt University and Director of the Vanderbilt Center for Neuroscience Drug Discovery (VCNDD). Dr Conn received a PhD in Pharmacology from Vanderbilt in 1986 and pursued postdoctoral studies at Yale University. He served as a professor of Pharmacology at Emory University from 1988 to 2000, before moving to Merck and Co. (PA, USA) as head of the Department of Neuroscience. Dr Conn moved to Vanderbilt University in 2003 where he is the founding director of the VCNDD, with a primary mission of facilitating translation of recent advances in basic science to novel therapeutics. The VCNDD consists of approximately 100 full-time scientists and has advanced novel molecules from four major programs as development candidates for clinical testing with industry partners. Dr Conn has served in editorial positions with multiple international journals and has served the scientific advisory boards of multiple foundations and companies. He has received numerous awards based on the impact of his basic and translational research. Dr Conn's current research is focused on development of novel treatment strategies for schizophrenia, Parkinson's disease and other serious brain disorders. Interview conducted by Hannah Coaker, Assistant Commissioning Editor.

  18. The RERTR Program status and progress

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Travelli, A.

    1995-12-01

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. The major events, findings, and activities of 1995 are reviewed after a brief summary of the results which the RERTR Program had achieved by the end of 1994. The revelation that Iraq was on the verge of developing a nuclear weapon at the time of the Gulf War, and that it was planning to do so by extracting HEU from the fuel of its research reactors, has given new impetus and urgency to the RERTR commitment of eliminating HEU use in research and test reactors worldwide.more » Development of advanced LEU research reactor fuels is scheduled to begin in October 1995. The Russian RERTR program, which aims to develop and demonstrate within the next five years the technical means needed to convert Russian-supplied research reactors to LEU fuels, is now in operation. A Statement of Intent was signed by high US and Chinese officials, endorsing cooperative activities between the RERTR program and Chinese laboratories involved in similar activities. Joint studies of LEU technical feasibility were completed for the SAFARI-I reactor in South Africa and for the ANS reactor in the US. A new study has been initiated for the FRM-II reactor in Germany. Significant progress was made on several aspects of producing {sup 99}Mo from fission targets utilizing LEU instead of HEU. A cooperation agreements is in place with the Indonesian BATAN. The first prototypical irradiation of an LEU metal-foil target for {sup 99}Mo production was accomplished in Indonesia. The TR-2 reactor, in Turkey, began conversion. SAPHIR, in Switzerland, was shut down. LEU fuel fabrication has begun for the conversion of two more US reactors. Twelve foreign reactors and nine domestic reactors have been fully converted. Approximately 60 % of the work required to eliminate the use of HEU in US-supplied research reactors has been accomplished.« less

  19. 75 FR 70042 - In the Matter of All Power Reactor Licensees and Research Reactor Licensees Who Transport Spent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... NUCLEAR REGULATORY COMMISSION [Docket Nos (Redacted), License Nos (Redacted), EA (Redacted); NRC- 2010-0351] In the Matter of All Power Reactor Licensees and Research Reactor Licensees Who Transport Spent Nuclear Fuel; Order Modifying License (Effective Immediately) I. The licensees identified in...

  20. 75 FR 79423 - In the Matter of All Power Reactor Licensees and Research Reactor Licensees Who Transport Spent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... NUCLEAR REGULATORY COMMISSION [Docket Nos. (Redacted), License Nos.: (Redacted), EA (Redacted); NRC- 2010-0351] In the Matter of All Power Reactor Licensees and Research Reactor Licensees Who Transport Spent Nuclear Fuel; Order Modifying License (Effective Immediately) I The licensees identified in...

  1. Direct assays of radiation-induced DNA base lesions in mammalian cells: Technical progress report, July 1, 1986--December 1, 1988

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wheeler, K.T. Jr.

    1988-01-01

    Our cesium irradiator was installed in April 1987 and has the capability of irradiating DNA solutions, cells and animals at dose rates from >60 Gy/min to <10/sup /minus/2/ Gy/min. By early summer all of the dosimetry and set-ups were established to perform this research. In may 1987, Dr. Krystyna Lesiak left to return to the National Institutes of Health. However, she has remained a collaborator over the past 1/1/2/ years. She has synthesized a large lot of ..cap alpha..-deoxyadenosine, isolated a large batch of both the R and S isomer of cyclodeoxyadenosine and has capped the ..cap alpha..-deoxyadenonsine for usemore » in a DNA synthesizer that uses phosphoramidite chemistry. In November 1987, Dr. Andrzej Surowiec joined our unit as a Visiting Research Assistant Professor. Dr. Surowiec has a MS degree in electrical engineering and did his Ph.D. in Biophysics studying the conductivity of DNA in dilute solution. He has been performing the helix-coil transition experiments. In November 1987, Dr. Steven Swarts also joined our unit as a Postdoctoral Fellow. He received his Ph.D. from Oakland University under Dr. Michael Sevilla with whom we have a collaboration studying the induction of base damage in hydrated DNA. Dr. Swarts has a strong background in spectroscopy and, therefore, was a key individual for determination of the limitations of the HPLC assays and the establishment of a GC/MS capability equivalent to Dr. M. Dizdaroglu at the National Bureau of Standards. 9 refs., 1 tab.« less

  2. Measuring financial well-being in cancer prevention research: Results from the Money-Health Connection Study

    Cancer.gov

    Dr. Reginald Tucker-Seeley joined the faculty at the University of Southern California (USC) Leonard Davis School of Gerontology in June 2017. Prior to joining USC, Dr. Tucker-Seeley was an Assistant Professor at the Dana-Farber Cancer Institute (DFCI) and the Harvard T.H. Chan School of Public Health (HSPH). He completed master and doctoral degrees at HSPH and a postdoctoral fellowship in cancer prevention and control at HSPH and DFCI. Dr. Tucker-Seeley’s research focuses primarily on social determinants of health, such as the association between the neighborhood environment and health behavior; and on individual-level socioeconomic determinants of multi-morbidity, mortality, self-rated health, and health self-efficacy. His current work focuses on financial well-being across the cancer continuum, from prevention to end-of-life care. He has received R21 and K01 grants from the National Cancer Institute (NCI) to develop measures of financial well-being at two points along the cancer continuum: prevention and following diagnosis. He was also funded by the Academy Health/Aetna Foundation Scholars in Residence Fellowship Program to develop measures of neighborhood economic well-being. Dr. Tucker-Seeley’s research has been published in journals such as the American Journal of Public Health, Preventive Medicine, Journal of National Cancer Institute, Cancer Causes and Control, and the American Journal of Preventive Medicine. Dr. Tucker-Seeley is also committed to community service that targets the elimination of health disparities. He served for three years on the Rhode Island Commission for Health Advocacy and Equity. Based on his experience on this Commission, Dr. Tucker-Seeley developed a new course at HSPH called “Measuring and Reporting Health Disparities;” and in 2016, he received the HSPH teaching award for this course.

  3. The origins of the modern pain clinic at the Mayo Clinic.

    PubMed

    Weingarten, Toby N; Martin, David P; Bacon, Douglas R

    2011-07-01

    In the 1970s the practice of pain management evolved from the isolated anesthesiologist practicing pain "on the side" to a multi-disciplinary model. The impetus behind this change remains obscure. To understand how this national trend occurred locally and to examine national institutional challenges which should be reflected at the Mayo Clinic that stimulated the establishment of a modern academic pain practice, we interviewed appropriate staff members and reviewed relevant departmental meeting notes. Following the 1959 departure of Dr. John Lundy from Mayo, Dr. Robert Jones became the primary practitioner of pain procedures in addition to his anesthesiology practice. In 1973, close to his retirement, Jones wrote a letter to the department chairman, Dr. Richard Theye, expressing frustration because this divided practice hindered patient care, education, and research opportunities. In 1974 Dr. Lee Nauss joined Mayo upon residency completion at Virginia Mason where he received training in regional anesthesia and met Dr. John Bonica. Nauss introduced epidural steroid injections, which became in such great demand that other anesthesiologists needed to cover his rooms. Within two months, Theye asked Nauss to create a stand-alone pain clinic. Nauss recruited Dr. Tony Wang and opened the clinic that year. This pain clinic increased patient access, improved resident education, allowed for the establishment of a fellowship program, and produced ground-breaking research (e.g., the human administration of intrathecal morphine). The establishment of the pain clinic addressed the deficiencies of a mixed pain and anesthesia practice. The pain specialist could now focus attention on and provide better access for pain patients, keep current with clinical practice, engage in research, and educate future pain specialists.

  4. A computer-based feedback only intervention with and without a moderation skills component.

    PubMed

    Weaver, Cameron C; Leffingwell, Thad R; Lombardi, Nathaniel J; Claborn, Kasey R; Miller, Mary E; Martens, Matthew P

    2014-01-01

    Research on the efficacy of computer-delivered feedback-only interventions (FOIs) for college alcohol misuse has been mixed. Limitations to these FOIs include participant engagement and variation in the use of a moderation skills component. The current investigation sought to address these limitations using a novel computer-delivered FOI, the Drinkers Assessment and Feedback Tool for College Students (DrAFT-CS). Heavy drinking college students (N=176) were randomly assigned to DrAFT-CS, DrAFT-CS plus moderation skills (DrAFT-CS+), moderation skills only (MSO), or assessment only (AO) group, and were assessed at 1-month follow-up (N=157). Participants in the DrAFT-CS and DrAFT-CS+groups reported significantly lower estimated blood alcohol concentrations (eBACs) on typical heaviest drinking day than participants in the AO group. The data also supported the incorporation of a moderation skills component within FOIs, such that participants in DrAFT-CS+group reported significantly fewer drinks per week and drinks per heaviest drinking occasion than participants in the AO group. © 2013.

  5. A computer-based feedback only intervention with and without a moderation skills component

    PubMed Central

    Weaver, Cameron C.; Leffingwell, Thad R.; Lombardi, Nathaniel J.; Claborn, Kasey R.; Miller, Mary E.; Martens, Matthew P.

    2014-01-01

    Research on the efficacy of computer-delivered feedback-only interventions (FOIs) for college alcohol misuse has been mixed. Limitations to these FOIs include participant engagement and variation in the use of a moderation skills component. The current investigation sought to address these limitations using a novel computer-delivered FOI, the Drinkers Assessment and Feedback Tool for College Students (DrAFT-CS). Heavy drinking college students (N = 176) were randomly assigned to DrAFT-CS, DrAFT-CS plus moderation skills (DrAFT-CS+), moderation skills only (MSO), or assessment only (AO) group, and were assessed at 1-month follow-up (N = 157). Participants in the DrAFT-CS and DrAFT-CS + groups reported significantly lower estimated blood alcohol concentrations (eBACs) on typical heaviest drinking day than participants in the AO group. The data also supported the incorporation of a moderation skills component within FOIs, such that participants in DrAFT-CS + group reported significantly fewer drinks per week and drinks per heaviest drinking occasion than participants in the AO group. PMID:24041748

  6. The life and contribution of Dr. Ronald Gitelman: a pioneer of modern chiropractic science.

    PubMed

    Vernon, Howard

    2013-03-01

    The life and contribution to chiropractic science of Dr. Ronald Gitelman is reviewed. Sources for this article included review of the notes prepared by Dr. Joseph Keating in his "biography" of the Canadian Memorial Chiropractic College (CMCC); review of the important articles published by Dr. Gitelman; review of the important projects undertaken by him along with various colleagues; notes from reminiscences obtained from many of these colleagues and discussions with his family. Dr. Gitelman's academic career spanned from 1963 to the late 1980's. During that time, he made foundational contributions to the development of chiropractic science including: developing the Archives (1974), the first collection of scientific articles supporting chiropractic science (which was subsequently published as the Chiropractic Archives Research Collection (CRAC)); delivering one of the few chiropractic papers at the seminal NINCDS conference (1975) and, developing the collaboration between CMCC and Dr. Kirkaldy-Willis at the University of Saskatoon (1976). He practiced in Toronto from 1961 to 2007. Dr. Gitelman was a pioneer in the development of chiropractic science. He died on October 7, 2012.

  7. Beyond 2012: Why the World Won't End A Discussion with Dr. David Morrison

    NASA Image and Video Library

    2012-12-18

    Dr. David Morrison, Astrobiologist and Senior Scientist at NASA Ames Research Center, addresses several theories that the world will end or face some kind of cosmic cataclysm on Friday December 21, 2012. Also known as the Doomsday Prophecy.

  8. 78 FR 68825 - Strategic Environmental Research and Development Program, Scientific Advisory Board; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-15

    ... (RC-2434)--FY14 Re-Brief, Dr. Jeffrey Foster, Northern Seed Dispersal Networks and Novel Arizona.... Sediments, and Biological Receptors. 1:25 p.m 14 ER03-025 (ER-2428)--FY14 New Start, Dr. Danny Reible, Texas...

  9. Computing and Systems Applied in Support of Coordinated Energy, Environmental, and Climate Planning

    EPA Science Inventory

    This talk focuses on how Dr. Loughlin is applying Computing and Systems models, tools and methods to more fully understand the linkages among energy systems, environmental quality, and climate change. Dr. Loughlin will highlight recent and ongoing research activities, including: ...

  10. All in the Family: The Sister Study

    MedlinePlus

    ... cohort of women. We are committed to enrolling women from all backgrounds, occupations, races, ethnicities and regions. Dr. Anna Nápoles-Springer, ... at the grassroots level, to enroll ethnic minority women, since historically we ... in research," says Dr. Nápoles-Springer. "Only by participating can ...

  11. A Civilian/Military Trauma Institute: National Trauma Research Coordinating Center

    DTIC Science & Technology

    2011-10-01

    Rebuttals, Q&A Salon A Craniofacial Trauma LtCol Cecila Schmalbach 1540-1550 Speaker: Dr. Manuel Lopez Title: OIF: Perspective of H&N Surgeon in...Intubation Endoscope. Station 10 Video Laryngoscope Dr. (Maj) Elvin Cruz , Staff Anesthesiologist, Wilford Hall Medical Center Practice video

  12. Photographer: Digital Telepresence: Dr Murial Ross's Virtual Reality Application for Neuroscience

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Photographer: Digital Telepresence: Dr Murial Ross's Virtual Reality Application for Neuroscience Research Biocomputation. To study human disorders of balance and space motion sickness. Shown here is a 3D reconstruction of a nerve ending in inner ear, nature's wiring of balance organs.

  13. World oil outlook. Hearings before the Committee on Energy and Natural Resources, United States Senate, One Hundredth Congress, First Session, January 22 and March 11, 1987

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1987-01-01

    Dr. James E. Akins, Ambassador to Saudi Arabia, James R. Schlesinger of the Georgetown Center for Strategic and International Studies, Dr. Daniel Dreyfus of the Gas Research Institute, Dr. Scott Jones of Chase Econometrics, Inc., and Dr. John H. Lichtblau of the Petroleum Industry Research Foundation were the principal witnesses at a hearing held to review the potential for another oil crisis due to reduced domestic production and exploration and a diminished capability in both areas. Statements made by several senators reviewed the dangers of depending upon Middle East oil imports and the threat of an energy problem more seriousmore » than those of 1973 and 1979. Of primary concern was the need to retain a healthy domestic petroleum industry in the wake of fluctuating prices and restrengthening of OPEC as a cartel. Additional material submitted by Americans for Energy Independence follows the two-day testimony of the 16 witnesses.« less

  14. History of the Kolff Laboratory turbine driven electrohydraulic artificial heart.

    PubMed

    Topaz, S R; Flinders, T; Topaz, H A; Jones, D

    1998-11-01

    The concept of an electrically powered total artificial heart has been pursued by Dr. Kolff and his associates since the 1960s. Since the 1980s these efforts have been concentrated upon the development of the electrohydraulic total artificial heart, a turbine pump powered by a brushless DC motor. Dr. Kolff realized the benefits of pulsatile flow and device response to Starling's Law, and these concepts have formed the basis of subsequent design decisions. Design iterations have both solved existing problems and exposed new challenges. The current device design is greatly improved over early attempts due to the incorporation of technologies that have recently become available as the result of progress in the fields of materials and electronics and due to the lessons learned over many years of research under the guidance of Dr. Kolff. This article describes, from its inception, the last major research project of Dr. Kolff prior to his retirement. The discussion centers around development, problems and their solutions, and the reasoning for given solutions.

  15. Consensus Statement on Research Definitions for Drug-Resistant Tuberculosis in Children.

    PubMed

    Seddon, James A; Perez-Velez, Carlos M; Schaaf, H Simon; Furin, Jennifer J; Marais, Ben J; Tebruegge, Marc; Detjen, Anne; Hesseling, Anneke C; Shah, Sarita; Adams, Lisa V; Starke, Jeffrey R; Swaminathan, Soumya; Becerra, Mercedes C

    2013-06-01

    Few children with drug-resistant (DR) tuberculosis (TB) are identified, diagnosed, and given an appropriate treatment. The few studies that have described this vulnerable population have used inconsistent definitions. The World Health Organization (WHO) definitions used for adults with DR-TB and for children with drug-susceptible TB are not always appropriate for children with DR-TB. The Sentinel Project on Pediatric Drug-Resistant Tuberculosis was formed in 2011 as a network of experts and stakeholders in childhood DR-TB. An early priority was to establish standardized definitions for key parameters in order to facilitate study comparisons and the development of an evidence base to guide future clinical management. This consensus statement proposes standardized definitions to be used in research. In particular, it suggests consistent terminology, as well as definitions for measures of exposure, drug resistance testing, previous episodes and treatment, certainty of diagnosis, site and severity of disease, adverse events, and treatment outcome. © The Author 2013. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weiss, Charles J.; Das, Partha Pratim; Higgins, Deanna LM

    Nickel complexes were prepared with diphosphine ligands that contain pendant amines, and these complexes catalytically oxidize primary and secondary alcohols to their respective aldehydes and ketones. Kinetic and mechanistic studies of these prospective electrocatalysts were performed to understand what influences the catalytic activity. For the oxidation of diphenylmethanol, the catalytic rates were determined to be dependent on the concentration of both the catalyst and the alcohol. The catalytic rates were found to be independent of the concentration of base and oxidant. The incorporation of pendant amines to the phosphine ligand results in substantial increases in the rate of alcohol oxidationmore » with more electron-donating substituents on the pendant amine exhibiting the fastest rates. We thank Dr. John C. Linehan, Dr. Elliott B. Hulley, Dr. Jonathan M. Darmon, and Dr. Elizabeth L. Tyson for helpful discussions. Research by CJW, PD, DLM, and AMA was supported by the US Department of Energy, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Research by MLH was supported as part of the Center for Molecular Electrocatalysis, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Basic Energy Sciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle.« less

  17. Steady state and LOCA analysis of Kartini reactor using RELAP5/SCDAP code: The role of passive system

    NASA Astrophysics Data System (ADS)

    Antariksawan, Anhar R.; Wahyono, Puradwi I.; Taxwim

    2018-02-01

    Safety is the priority for nuclear installations, including research reactors. On the other hand, many studies have been done to validate the applicability of nuclear power plant based best estimate computer codes to the research reactor. This study aims to assess the applicability of the RELAP5/SCDAP code to Kartini research reactor. The model development, steady state and transient due to LOCA calculations have been conducted by using RELAP5/SCDAP. The calculation results are compared with available measurements data from Kartini research reactor. The results show that the RELAP5/SCDAP model steady state calculation agrees quite well with the available measurement data. While, in the case of LOCA transient simulations, the model could result in reasonable physical phenomena during the transient showing the characteristics and performances of the reactor against the LOCA transient. The role of siphon breaker hole and natural circulation in the reactor tank as passive system was important to keep reactor in safe condition. It concludes that the RELAP/SCDAP could be use as one of the tool to analyse the thermal-hydraulic safety of Kartini reactor. However, further assessment to improve the model is still needed.

  18. Interview with Janet Woodcock: progress on the FDA's critical path initiative.

    PubMed

    Woodcock, Janet

    2009-12-01

    Janet Woodcock is the Director of the US FDA's Center for Drug Evaluation and Research. Dr Woodcock has held various positions within the FDA's Office of the Commissioner from October 2003 until 1 April, 2008, as Deputy Commissioner and Chief Medical Officer, Deputy Commissioner for Operations and Chief Operating Officer and Director of the Critical Path Programs. She oversaw scientific and medical regulatory operations for the FDA. Dr Woodcock served as Director of the Center for Drug Evaluation and Research at the FDA from 1994 to 2005. She previously served in other positions at the FDA including Director of the Office of Therapeutics Research and Review and Acting Deputy Director of the Center for Biologics Evaluation and Research. Dr Woodcock received her MD from Northwestern Medical School (IL, USA), and completed further training and held teaching appointments at the Pennsylvania State University (PA, USA)and the University of California in San Francisco (CA, USA). She joined the FDA in 1986.

  19. Developing Nationally Competitive NASA Research Capability in West Virginia

    NASA Technical Reports Server (NTRS)

    Calzonetti, Frank J.

    1997-01-01

    In May, 1995 West Virginia EPSCOR was awarded $150,000 to support activities to develop research capabilities in West Virginia in support of the National Aeronautics and Space Administration (NASA). These funds were used to support three projects: 1) Information Processing and the Earth Observing System, directed by Dr. Stuart Tewksbury of West Virginia University; 2) Development of Optical Materials for Atmospheric Sensing Experiments, directed by Dr. Nancy Giles of West Virginia University; and 3) Development of Doppler Global Velocimeter (DGV) for Aeronautical and Combustion Studies, directed by Dr. John Kuhlman of West Virginia University. The funding provides the means to develop capability in each of these areas. This report summarizes the technical accomplishments in each project supported under this award.

  20. Mechanical Properties of Infrared Transmitting Materials

    DTIC Science & Technology

    1978-01-01

    Sea Systems Command Dr. Roy Rice, Naval Research Laboratory Dr. E. T. Salkovitz, Office of Naval Research Mr. George sorkin. Naval Sea Systems...speeds of the combatants, missile velocities are generally below Mach 4 at sea level, and below Mach 7 at 60,000 feet. From the discussion in...Table III.2 presents typical data for sea level and 11,000 m altitude (bottom of the stratosphere) and a variety of Mach numbers. The viscosity

  1. USAF Summer Faculty Research Program. 1980. Research Reports. Volume II.

    DTIC Science & Technology

    1980-10-01

    Radiation Damage Profiles and Annealing Dr. Samuel C. Ling Effects of 120 keV Sulfur Implants in GaAs 45 Finite Element Modeling of Elastic-Plastic Dr...described more fully in a later section. II. OBJECTIVES: Laboratory management is acutely aware of the shortcomings of the current informational processes...are fixed, there are only two modes of heat trans- fer - radiation and conduction. At the low temperatures necessary for superconductivity, radiation

  2. Spectroscopic Analysis of PbO Chemiluminescence.

    DTIC Science & Technology

    1981-12-01

    laser theory and spectroscopy . I wish to thank Dr. Steve Davis for providing some of the equipment used in this research and Dr. E. A. Dorko, my...is due to the Air Force’s interest in chemical lasers . Knowledge gained from this research will provide the Air Force Weapons Laboratory with data...which will indicate possible directions to follow in chemical laser development. I personally chose this thesis topic because of a keen interest in both

  3. Shortwave Hyperspectral Observations During MAGIC Final Campaign Summary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McBride, P. J.; Marshak, A.; Yang, W.

    The Marine ARM GPCI1 Investigation of Clouds (MAGIC) field campaign was initiated to improve our understanding of low-level marine clouds that have a significant influence on the Earth’s climate. The campaign was conducted using an ARM mobile facility deployed on a commercial ship traveling between Honolulu, Hawaii, and Los Angeles, California, from October 2012 to September 2013. The solar spectral flux radiometer (SSFR) was deployed on July 6, 2013, through the end of the campaign. The SSFR was calibrated and installed by Warren Gore of NASA Ames Research Center, and the data is and will be analyzed by Drs. Alexandermore » Marshak and Weidong Yang of NASA Goddard Space Flight Center, Dr. Samuel LeBlanc of NASA Ames Research Center, Dr. Sebastian Schmidt of the University of Colorado-Boulder, and Dr. Patrick McBride of Atmospheric & Space Technology Research Associates in Boulder, Colorado.« less

  4. Models for Multidimensional Tests and Hierarchically Structured Training Materials.

    DTIC Science & Technology

    1985-05-01

    NAVOP 01B7 Washington, DC 20370 Dr. Hans Crombag University of Leyden Mr. Raymond E. Christal Education Research Center AFHRL/MOE Boerhaavelaan 2 Brooks...AFB, TX 78235 2334 EN Leyden The NETHERLANDS Dr. Norman Cliff Department of Psychology CTB/McGraw-Hill Library Univ. of So. Californ.a 2500 Garden Road...Diego, CA 92152 A[USTRALIA Ms. Kathleen Moreno Dr. William L. Maloy (02) Navy Personnel R&D Center Chief of Naval Education Code 62 and Training San Diego

  5. Diffusion and Equilibrium Swelling of Macromolecular Networks by Their Linear Homologs.

    DTIC Science & Technology

    1982-10-01

    C/ . 29 OYN 6/81 DISTRIBUTION LIST No. Copies No. Copies Dr. L.V. Schmtdt 1 Dr. F. Roberto 1 Assistant Secretary of the Navy Code AFRPL MKPA (RE, and...Scientific Advisor Directorate of Aerospace Sciences Commandant of the Marine Corps Bolling Air Force Base Code RD-1 Washington, D.C. 20332 Washington...Directorate of Chemical Sciences Arlington VA 22217 Bolling Air Force Base t VWashington, D.C. 20332 Mr. David Siegel Office of Naval Research Dr. John S

  6. United States Air Force Summer Faculty Research Program 1989. Program Technical Report. Volume 1

    DTIC Science & Technology

    1989-12-01

    Amy Miller Transition-Metal Compounds ; Reactions of Iron and Iron Carbonyl Anions 59 Acidities of Iron Hydride and Various Dr. Thomas Miller...Transition-Metal Compounds ; Reactions of Iron and Iron Carbonyl Anions (Same Report as Dr. Amy Miller) 60 C02(4.3pm) Vibrational Temperatures and Dr. Henry...Release. Table VIII gives data on the the two alloy systems, Pd/Al and Ni/Al. It also gives some properties of the compound , Pd/Hz. A brief description of

  7. European Science Notes Information Bulletin (ESNIB) Reports on Current European/Middle Eastern Science

    DTIC Science & Technology

    1988-12-01

    Buckingham’s Work ............... David Felt 3 The underwater acoustics research currently being pursued by Dr. Michael Buckingham and his col- league...to the US ASW community. Dr. Stanfield was an exchange scientist at the Naval Air De- While at MIT Dr. Buckingham , in addition to his re- velopment...Theoretical Acoustics Group partments. As a result of one such collaboration he pub- lished a paper ( Buckingham and Chi-fang, 1987) with During my visit I

  8. Corneal Protection for Burn Patients

    DTIC Science & Technology

    2013-07-01

    Army Institute for Surgical Research (USISR) (by Dr. Johnson s group). This report covers results from Dr. Kochevar s lab and Dr. Johnson is...superluminensent diode source centered at 855 nm to provide an axial resolution of approximately 3 pm. A pair of galvanometric mirrors coupled to a Ziess...Bengal in PBS for 5 min, then exposed to 0, 5 or 50 J/cm2 532 nm light from a cw KTP laser , as reported previously. A weighed portion (—1 mg) was used

  9. Final Report on A. R. A. P.’s Model for the Atmospheric Marine Environment

    DTIC Science & Technology

    1982-01-01

    Around Airports," NASA CR-2752, prepared by A.R.A.P. for Marshall Space Center. 25. Brost , R.A. and Wyngaard, N.C., 1978: "A Model Study of the...FRANCE DR. R. A. BROST NCAR P.O. BOX 3000 BOULDER, CO 80307 JOHNS HOPKINS UNIV. APPLIED PHYSICS LAB R.E. GIBSON LIBRARY JOHNS HOPKINS ROAD...RESEARCH LABS BOULDER, CO 80303 DR. GEORGE L. HELLOR GEOPHYSICAL FLUID DYNAMICS LAE PRINCETON, NJ 08540 DR. TETSUJI YAMADA LOS ALAMOS NATIONAL LAB

  10. KSC-04PD-1985

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Principal Albert Sye, astronaut Leland Melvin, Dr. Julian Earls and KSC Deputy Director Dr. Woodrow Whitlow Jr. share the stage at Ronald E. McNair High School in Atlanta, a NASA Explorer School. Dr. Earls is director of the NASA Glenn Research Center. He joined Dr. Whitlow on a visit to the school to share the vision for space exploration with the next generation of explorers. Whitlow talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space. Dr. Earls discussed the future and the vision for space, plus the NASA careers needed to meet the vision. Melvin talked about the importance of teamwork and what it takes for mission success.

  11. Sweetened beverages and health: current state of scientific understandings.

    PubMed

    Rippe, James M; Saltzman, Edward

    2013-09-01

    This article summarizes the presentations from the "Sweetened Beverages and Health: Current State of Scientific Understandings" symposium held at the ASN Annual Meeting in Boston, MA on April 23, 2013. The metabolic and health effects of sugar-sweetened beverages were discussed from a variety of points of view by 5 different presenters. Dr. David Allison drew a distinction between conjecture and proof related to sweetened beverages and obesity. Dr. Richard Mattes discussed differences between solid and liquid calories. Dr. Miguel Alonso-Alonso reviewed potential contributions of functional neuroimaging, particularly as they relate to whether sugar is potentially "addictive." Dr. Kimber Stanhope discussed work related to experiments comparing fructose to glucose. Dr. James Rippe presented evidence from randomized controlled trials from his research organization showing no differences among high-fructose corn syrup, sucrose, glucose, or fructose at normal human consumption amounts.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    Digital instrumentation and controls system technique is being introduced in new constructed research reactor or life extension of older research reactor. Digital systems are easy to change and optimize but the validated process for them is required. Also, to reduce project risk or cost, we have to make it sure that configuration and control functions is right before the commissioning phase on research reactor. For this purpose, simulators have been widely used in developing control systems in automotive and aerospace industries. In these literatures, however, very few of these can be found regarding test on the control system of researchmore » reactor with simulator. Therefore, this paper proposes a simulation platform to verify the performance of RRS (Reactor Regulating System) for research reactor. This simulation platform consists of the reactor simulation model and the interface module. This simulation platform is applied to I and C upgrade project of TRIGA reactor, and many problems of RRS configuration were found and solved. And it proved that the dynamic performance testing based on simulator enables significant time saving and improves economics and quality for RRS in the system test phase. (authors)« less

  13. Traffic Flow Management and Optimization

    NASA Technical Reports Server (NTRS)

    Rios, Joseph Lucio

    2014-01-01

    This talk will present an overview of Traffic Flow Management (TFM) research at NASA Ames Research Center. Dr. Rios will focus on his work developing a large-scale, parallel approach to solving traffic flow management problems in the national airspace. In support of this talk, Dr. Rios will provide some background on operational aspects of TFM as well a discussion of some of the tools needed to perform such work including a high-fidelity airspace simulator. Current, on-going research related to TFM data services in the national airspace system and general aviation will also be presented.

  14. Effects of Granular Control on Customers’ Perspective and Behavior with Automated Demand Response Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schetrit, Oren; Kim, Joyce; Yin, Rongxin

    2014-08-01

    Automated demand response (Auto-DR) is expected to close the loop between buildings and the grid by providing machine-to-machine communications to curtail loads without the need for human intervention. Hence, it can offer more reliable and repeatable demand response results to the grid than the manual approach and make demand response participation a hassle-free experience for customers. However, many building operators misunderstand Auto-DR and are afraid of losing control over their building operation. To ease the transition from manual to Auto-DR, we designed and implemented granular control of Auto-DR systems so that building operators could modify or opt out of individualmore » load-shed strategies whenever they wanted. This paper reports the research findings from this effort demonstrated through a field study in large commercial buildings located in New York City. We focused on (1) understanding how providing granular control affects building operators’ perspective on Auto-DR, and (2) evaluating the usefulness of granular control by examining their interaction with the Auto-DR user interface during test events. Through trend log analysis, interviews, and surveys, we found that: (1) the opt-out capability during Auto-DR events can remove the feeling of being forced into load curtailments and increase their willingness to adopt Auto-DR; (2) being able to modify individual load-shed strategies allows flexible Auto-DR participation that meets the building’s changing operational requirements; (3) a clear display of automation strategies helps building operators easily identify how Auto-DR is functioning and can build trust in Auto-DR systems.« less

  15. Global Prevalence and Major Risk Factors of Diabetic Retinopathy

    PubMed Central

    Yau, Joanne W.Y.; Rogers, Sophie L.; Kawasaki, Ryo; Lamoureux, Ecosse L.; Kowalski, Jonathan W.; Bek, Toke; Chen, Shih-Jen; Dekker, Jacqueline M.; Fletcher, Astrid; Grauslund, Jakob; Haffner, Steven; Hamman, Richard F.; Ikram, M. Kamran; Kayama, Takamasa; Klein, Barbara E.K.; Klein, Ronald; Krishnaiah, Sannapaneni; Mayurasakorn, Korapat; O’Hare, Joseph P.; Orchard, Trevor J.; Porta, Massimo; Rema, Mohan; Roy, Monique S.; Sharma, Tarun; Shaw, Jonathan; Taylor, Hugh; Tielsch, James M.; Varma, Rohit; Wang, Jie Jin; Wang, Ningli; West, Sheila; Xu, Liang; Yasuda, Miho; Zhang, Xinzhi; Mitchell, Paul; Wong, Tien Y.

    2012-01-01

    OBJECTIVE To examine the global prevalence and major risk factors for diabetic retinopathy (DR) and vision-threatening diabetic retinopathy (VTDR) among people with diabetes. RESEARCH DESIGN AND METHODS A pooled analysis using individual participant data from population-based studies around the world was performed. A systematic literature review was conducted to identify all population-based studies in general populations or individuals with diabetes who had ascertained DR from retinal photographs. Studies provided data for DR end points, including any DR, proliferative DR, diabetic macular edema, and VTDR, and also major systemic risk factors. Pooled prevalence estimates were directly age-standardized to the 2010 World Diabetes Population aged 20–79 years. RESULTS A total of 35 studies (1980–2008) provided data from 22,896 individuals with diabetes. The overall prevalence was 34.6% (95% CI 34.5–34.8) for any DR, 6.96% (6.87–7.04) for proliferative DR, 6.81% (6.74–6.89) for diabetic macular edema, and 10.2% (10.1–10.3) for VTDR. All DR prevalence end points increased with diabetes duration, hemoglobin A1c, and blood pressure levels and were higher in people with type 1 compared with type 2 diabetes. CONCLUSIONS There are approximately 93 million people with DR, 17 million with proliferative DR, 21 million with diabetic macular edema, and 28 million with VTDR worldwide. Longer diabetes duration and poorer glycemic and blood pressure control are strongly associated with DR. These data highlight the substantial worldwide public health burden of DR and the importance of modifiable risk factors in its occurrence. This study is limited by data pooled from studies at different time points, with different methodologies and population characteristics. PMID:22301125

  16. Influence of auxochrome group in disperse dyes bearing azo groups as chromophore center in the biotransformation and molecular docking prediction by reductase enzyme: Implications and assessment for environmental toxicity of xenobiotics.

    PubMed

    Franco, Jefferson Honorio; da Silva, Bianca F; Dias, Elisangela Franciscon G; de Castro, Alexandre A; Ramalho, Teodorico C; Zanoni, Maria Valnice Boldrin

    2018-05-21

    Synthetic azo dyes have increasingly become a matter of great concern as a result of the genotoxic and mutagenic potential of the products derived from azo dye biotransformation. This work evaluates the manner in which reducing enzymes produced by Escherichia coli (E. coli) act on three disperse dyes bearing azo groups, namely Disperse Red 73 (DR 73), Disperse Red 78 (DR 78), and Disperse Red 167 (DR 167). UV-Vis spectrophotometry, high-performance liquid chromatography with diode array detector (HPLC-DAD), and liquid chromatography mass spectrometry (LC-MS/MS) were applied towards the identification of the main products. Seven days of incubation of the azo dyes with the tested enzymes yielded a completely bleached solution. 3-4-Aminophenyl-ethyl-amino-propanitrile was detected following the biotransformation of both DR 73 and DR 78. 4-Nitroaniline and 2-chloro-4-nitroaniline were detected upon the biotransformation of DR 73 and DR 78, respectively. The main products derived from the biotransformation of DR 167 were dimethyl 3,3'-3-acetamido-4-aminophenyl-azanedyl-dipropanoate and 2-chloro-4-nitroaniline. The results imply that DR 73 lost the CN - substituent during the biotransformation. Furthermore, theoretical calculations were also carried out aiming at evaluating the interaction and reactivity of these compounds with DNA. Taken together, the results indicate that DR 73, DR 78, and DR 167 pose health risks and serious threats to both human beings and the environment at large as their biotransformation produces harmful compounds such as amines, which have been widely condemned by the International Agency for Research on Cancer. Copyright © 2018. Published by Elsevier Inc.

  17. 75 FR 27368 - Aerotest Operations, Inc., Aerotest Radiography and Research Reactor; Notice of Consideration of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ...., Aerotest Radiography and Research Reactor; Notice of Consideration of Approval of Transfer and Conforming Amendment, Opportunity for a Hearing, and Order Imposing Procedures for Access to Sensitive Unclassified Non... Manager, Research and Test Reactors Licensing Branch, Division of Policy and Rulemaking, Office of Nuclear...

  18. A Potential NASA Research Reactor to Support NTR Development

    NASA Technical Reports Server (NTRS)

    Eades, Michael; Gerrish, Harold; Hardin, Leroy

    2013-01-01

    In support of efforts for research into the design and development of a man rated Nuclear Thermal Rocket (NTR) engine, the National Aeronautics and Space Administration (NASA), Marshall Space Flight Center (MSFC), is evaluating the potential for building a Nuclear Regulatory Commission (NRC) licensed research reactor. The proposed reactor would be licensed by NASA and operated jointly by NASA and university partners. The purpose of this reactor would be to perform further research into the technologies and systems needed for a successful NTR project and promote nuclear training and education.

  19. The Research of Dr. Joanne Simpson: Fifty Years Investigating Hurricanes, Tropical Clouds and Cloud Systems

    NASA Technical Reports Server (NTRS)

    Tao, W. -K.; Halverson, J.; Adler, R.; Garstang, M.; Houze, R., Jr.; LeMone, M.; Pielke, R., Sr.; Woodley, W.; O'C.Starr, David (Technical Monitor)

    2001-01-01

    This AMS Meteorological Monographs is dedicated to Dr. Joanne Simpson for her many pioneering research efforts in tropical meteorology during her fifty-year career. Dr. Simpson's major areas of scientific research involved the "hot tower" hypothesis and its role in hurricanes, structure and maintenance of trade winds, air-sea interaction, and observations and the mechanism for hurricanes and waterspouts. She was also a pioneer in cloud modeling with the first one-dimensional model and had the first cumulus model on a computer. She also played a major role in planning and leading observational experiments on convective cloud systems. The launch of the Tropical Rainfall Measuring Mission (TRMM) satellite, a joint U.S.-Japan project, in November of 1997 made it possible for quantitative measurements of tropical rainfall to be obtained on a continuous basis over the entire global tropics. Dr. Simpson was the TRAM Project Scientist from 1986 until its launch in 1997. Her efforts during this crucial period ensured that the mission was both well planned scientifically and well engineered as well as within budget. In this paper, Dr. J. Simpson's nine specific accomplishments during her fifty-year career: (1) hot tower hypothesis, (2) hurricanes, (3) airflow and clouds over heated islands, (4) cloud models, (5) trade winds and their role in cumulus development, (6) air-sea interaction, (7) cloud-cloud interactions and mergers, (8) waterspouts, and (9) TRMM science, will be described and discussed.

  20. RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis.

    PubMed

    Brünker, Peter; Wartha, Katharina; Friess, Thomas; Grau-Richards, Sandra; Waldhauer, Inja; Koller, Claudia Ferrara; Weiser, Barbara; Majety, Meher; Runza, Valeria; Niu, Huifeng; Packman, Kathryn; Feng, Ningping; Daouti, Sherif; Hosse, Ralf J; Mössner, Ekkehard; Weber, Thomas G; Herting, Frank; Scheuer, Werner; Sade, Hadassah; Shao, Cuiying; Liu, Bin; Wang, Peng; Xu, Gary; Vega-Harring, Suzana; Klein, Christian; Bosslet, Klaus; Umaña, Pablo

    2016-05-01

    Dysregulated cellular apoptosis and resistance to cell death are hallmarks of neoplastic initiation and disease progression. Therefore, the development of agents that overcome apoptosis dysregulation in tumor cells is an attractive therapeutic approach. Activation of the extrinsic apoptotic pathway is strongly dependent on death receptor (DR) hyperclustering on the cell surface. However, strategies to activate DR5 or DR4 through agonistic antibodies have had only limited clinical success. To pursue an alternative approach for tumor-targeted induction of apoptosis, we engineered a bispecific antibody (BsAb), which simultaneously targets fibroblast-activation protein (FAP) on cancer-associated fibroblasts in tumor stroma and DR5 on tumor cells. We hypothesized that bivalent binding to both FAP and DR5 leads to avidity-driven hyperclustering of DR5 and subsequently strong induction of apoptosis in tumor cells but not in normal cells. Here, we show that RG7386, an optimized FAP-DR5 BsAb, triggers potent tumor cell apoptosis in vitro and in vivo in preclinical tumor models with FAP-positive stroma. RG7386 antitumor efficacy was strictly FAP dependent, was independent of FcR cross-linking, and was superior to conventional DR5 antibodies. In combination with irinotecan or doxorubicin, FAP-DR5 treatment resulted in substantial tumor regression in patient-derived xenograft models. FAP-DR5 also demonstrated single-agent activity against FAP-expressing malignant cells, due to cross-binding of FAP and DR5 across tumor cells. Taken together, these data demonstrate that RG7386, a novel and potent antitumor agent in both mono- and combination therapies, overcomes limitations of previous DR5 antibodies and represents a promising approach to conquer tumor-associated resistance to apoptosis. Mol Cancer Ther; 15(5); 946-57. ©2016 AACR. ©2016 American Association for Cancer Research.

  1. The Thoc1 Ribonucleoprotein as a Novel Biomarker for Prostate Cancer Treatment Assignment

    DTIC Science & Technology

    2015-10-01

    REPORT NUMBER Health Research Inc. and Roswell Park Cancer Institute Elm & Carlton Streets Buffalo, NY 14263-0001 9. SPONSORING / MONITORING AGENCY...Synergistic Idea Development Award in collaboration with Dr. James Mohler (Partnering PI, Roswell Park Cancer Institute). Dr. Mohler will be

  2. ARC-2008-ACD08-0175-004

    NASA Image and Video Library

    2008-08-07

    Dr Aubrey de Grey presents a Director's Colloquium to the NASA Ames Research Center staff entitled 'Prospects for defeating aging altogether' Dr. de Grey is a British bomedical gerontologist educated at Cambridge University in the UK. A video of the presentation is currently available at the NASA Ames Library.

  3. ARC-2008-ACD08-0175-006

    NASA Image and Video Library

    2008-08-07

    Dr Aubrey de Grey presents a Director's Colloquium to the NASA Ames Research Center staff entitled 'Prospects for defeating aging altogether' Dr. de Grey is a British bomedical gerontologist educated at Cambridge University in the UK. A video of the presentation is currently available at the NASA Ames Library.

  4. ARC-2008-ACD08-0175-009

    NASA Image and Video Library

    2008-08-07

    Dr Aubrey de Grey presents a Director's Colloquium to the NASA Ames Research Center staff entitled 'Prospects for defeating aging altogether' Dr. de Grey is a British bomedical gerontologist educated at Cambridge University in the UK. A video of the presentation is currently available at the NASA Ames Library.

  5. ARC-2008-ACD08-0175-007

    NASA Image and Video Library

    2008-08-07

    Dr Aubrey de Grey presents a Director's Colloquium to the NASA Ames Research Center staff entitled 'Prospects for defeating aging altogether' Dr. de Grey is a British bomedical gerontologist educated at Cambridge University in the UK. A video of the presentation is currently available at the NASA Ames Library.

  6. Transgenic Rat Models for Breast Cancer Research

    DTIC Science & Technology

    1996-10-01

    colleagues, Dr. Henry Pitot , an expert in hepatocarcinogenesis, and Dr. Michael Gould, an expert in breast cancer. Through our initial attempts at...974-978. 29. Dragan, Y.P. and H.C. Pitot . 1992. The role of the stages of initiation and promotion in phenotypic diversity during hepatocarcinogenesis

  7. Diabetic Retinopathy in the Asia-Pacific.

    PubMed

    Chua, Jacqueline; Lim, Claire Xin Ying; Wong, Tien Yin; Sabanayagam, Charumathi

    2018-01-01

    Diabetic retinopathy (DR), the most common complication of diabetes mellitus, is the leading cause of new cases of blindness in middle-aged and elderly in the Asia-Pacific. It has been estimated that 51% of all those with blindness due to DR globally (n = 424,400) and 56% of those with visual impairment due to DR (2.1 million) come from the Asia-Pacific. Prevalence of DR among those with diabetes ranged from 10% in India to 43% in Indonesia within the Asia-Pacific. Awareness of DR among persons with diabetes ranged from 28% to 84%. Most common modifiable risk factors for DR in the Asia-Pacific were hyperglycemia, blood pressure, dyslipidemia, and obesity. Implementation of systematic screening programs for DR and advancement in telemedicine screening methods have increased patient coverage and cost-effectiveness, though there are still numerous factors impeding screening uptake in the low-middle income regions of the Asia-Pacific. Management and treatment of DR in the Asia-Pacific is mainly limited to traditional laser retinopexy, but it is suboptimal despite new clinical approaches such as use of intravitreal anti.vascular endothelial growth factor and steroids due to limited resources. Further research and data are required to structure a more cost-effective public healthcare program and more awareness-building initiatives to increase the effectiveness of DR screening programs. Copyright 2017 Asia-Pacific Academy of Ophthalmology.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Progress is reported on fundamental research in: crystal physics, reactions at metal surfaces, spectroscopy of ionic media, structure of metals, theory of alloying, physical properties, sintering, deformation of crystalline solids, x ray diffraction, metallurgy of superconducting materials, and electron microscope studies. Long-randge applied research studies were conducted for: zirconium metallurgy, materials compatibility, solid reactions, fuel element development, mechanical properties, non-destructive testing, and high-temperature materials. Reactor development support work was carried out for: gas-cooled reactor program, molten-salt reactor, high-flux isotope reactor, space-power program, thorium-utilization program, advanced-test reactor, Army Package Power Reactor, Enrico Fermi fast-breeder reactor, and water desalination program. Other programmore » activities, for which research was conducted, included: thermonuclear project, transuraniunn program, and post-irradiation examination laboratory. Separate abstracts were prepared for 30 sections of the report. (B.O.G.)« less

  9. Integrated Decision-Making Tool to Develop Spent Fuel Strategies for Research Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beatty, Randy L; Harrison, Thomas J

    IAEA Member States operating or having previously operated a Research Reactor are responsible for the safe and sustainable management and disposal of associated radioactive waste, including research reactor spent nuclear fuel (RRSNF). This includes the safe disposal of RRSNF or the corresponding equivalent waste returned after spent fuel reprocessing. One key challenge to developing general recommendations lies in the diversity of spent fuel types, locations and national/regional circumstances rather than mass or volume alone. This is especially true given that RRSNF inventories are relatively small, and research reactors are rarely operated at a high power level or duration typical ofmore » commercial power plants. Presently, many countries lack an effective long-term policy for managing RRSNF. This paper presents results of the International Atomic Energy Agency (IAEA) Coordinated Research Project (CRP) #T33001 on Options and Technologies for Managing the Back End of the Research Reactor Nuclear Fuel Cycle which includes an Integrated Decision Making Tool called BRIDE (Back-end Research reactor Integrated Decision Evaluation). This is a multi-attribute decision-making tool that combines the Total Estimated Cost of each life-cycle scenario with Non-economic factors such as public acceptance, technical maturity etc and ranks optional back-end scenarios specific to member states situations in order to develop a specific member state strategic plan with a preferred or recommended option for managing spent fuel from Research Reactors.« less

  10. Comparison of Actual Costs to Integrate Commercial Buildings with the Grid

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Piette, Mary Ann; Black, Doug; Yin, Rongxin

    During the past decade, the technology to automate demand response (DR) in buildings and industrial facilities has advanced significantly. Automation allows rapid, repeatable, reliable operation. This study focuses on costs for DR automation in commercial buildings with some discussion on residential buildings and industrial facilities. DR automation technology relies on numerous components, including communication systems, hardware and software gateways, standards-based messaging protocols, controls and integration platforms, and measurement and telemetry systems. This paper discusses the impact factors that contribute to the costs of automated DR systems, with a focus on OpenADR 1.0 and 2.0 systems. In addition, this report comparesmore » cost data from several DR automation programs and pilot projects, evaluates trends in the cost per unit of DR and kilowatts (kW) available from automated systems, and applies a standard naming convention and classification or taxonomy for system elements. In summary, median costs for the 56 installed automated DR systems studied here are about $200/kW. The deviation around this median is large with costs in some cases being an order of magnitude greater or less than median. Costs to automate fast DR systems for ancillary services are not fully analyzed in this report because additional research is needed to determine the total such costs.« less

  11. Citation analysis of Canadian psycho-oncology and supportive care researchers.

    PubMed

    Hack, Thomas F; Crooks, Dauna; Plohman, James; Kepron, Emma

    2014-02-01

    The purpose of this study was to conduct a historical review of psycho-oncology and supportive care research in Canada using citation analysis and to review the clinical impact of the research conducted by the most highly cited researchers. The lifetime journal publication records of 109 psycho-oncology and supportive care researchers in Canada were subject to citation analysis using the Scopus database, based on citations since 1996 of articles deemed relevant to psychosocial oncology and supportive care, excluding self-citations. Three primary types of analysis were performed for each individual: the number of citations for each journal publication, a summative citation count of all published articles, and the Scopus h-index. The top 20 psycho-oncology/supportive care researchers for each of five citation categories are presented: the number of citations for all publications; the number of citations for first-authored publications; the most highly cited first-authored publications; the Scopus h-index for all publications; and the Scopus h-index for first-authored publications. The three most highly cited Canadian psycho-oncology researchers are Dr. Kerry Courneya (University of Alberta), Dr. Lesley Degner, (University of Manitoba), and Dr. Harvey Chochinov (University of Manitoba). Citation analysis is useful for examining the research performance of psycho-oncology and supportive care researchers and identifying leaders among them.

  12. Monolithic Integrated Radiation Sensor Using Stimulated Luminescence From Alumina

    NASA Technical Reports Server (NTRS)

    McKeever, S. W. S.; Yukihara, E. G.; Stoebe, T. G.; Chen, T.-C.

    2005-01-01

    The project goal was to design and test a monolithic integrated device for radiation sensing, using optically stimulated luminescence (OSL) from Al2O3:C. The device would consist of GaN/InGaN-based components epitaxially grown on each side of a A12O3:C substrate. Radiation energy stored in the substrate would be stimulated by visible emission from a GaN light-emitting diode (LED) grown on one side of the device, and the OSL emission from the substrate (in the blue region of the spectrum) would be detected by the InGaN pi-n diode grown on the other side of the substrate. The primary application of the device would be in space radiation environments. Thus, two major research thrusts were launched during this project. Firstly, research at Oklahoma State University (Dr. Stephen W.S. McKeever and Dr. E.G. Yukihara) concentrated on characterization of the OSL properties of Al2O3:C in radiation fields typical of those experienced in low-Earth orbit. Secondly, research at the University of Washington (Co-Is, Dr. T.G. Stoebe and Dr. T. Chen) focused of device development and GaN/InGaN epitaxial growth. While progress in each line of research has been substantial, the ultimate goal (that of producing a working prototype device) has not yet been reached. We detail the research progress and identify outstanding issues in this paper.

  13. Study of Tungsten effect on CFETR performance

    NASA Astrophysics Data System (ADS)

    Shi, Shengyu; Xiang Gao Collaboration; Guoqiang Li Collaboration; Nan Shi Collaboration; Vincent Chan Collaboration; Xiang Jian Collaboration

    2017-10-01

    An integrated modeling workflow using OMFIT/TGYRO is constructed to evaluate W impurity effects on China Fusion Engineering Test Reactor (CFETR) performance. Self-consistent modeling of tungsten(W) core density profile, accounting for turbulence and neoclassical transport, is performed based on the CFETR steady-state scenario developed by D.Zhao (ZhaoDeng, APS, 2016). It's found that the fusion performance degraded in a limited level with increasing W concentration. The main challenge arises in sustainment of H-mode with significant W radiation. Assuming the power threshold of H-L back transition is approximately the same as that of L-H transition, using the scaling law of Takizuka (Takizuka etc, Plasma Phys. Control. Fusion, 2004), it is found that the fractional W concentration should not exceed 3e-5 to stay in H-mode for CFETR phase I. A future step is to connect this requirement to W wall erosion modeling. We are grateful to Dr. Emiliano Fable and Dr. Thomas Pütterich and Ms. Emily Belli for very helpful discussions and comments. We also would like to express our thanks to all the members of the CFETR Physics Group, and we appreciate the General Atomic Theory Group for permission to use the OMFIT framework and GA code suite, and for their valuable technical support. Numerical computations were performed on the ShenMa High Performance Computing Cluster in the Institute of Plasma Physics, Chinese Academy of Sciences. This work was mainly supported by the National Magnetic Confinement Fusion Research Program of China (Grant Nos. 2014GB110001, 2014GB110002, 2014GB110003) and supported in part by the National ITER Plans Program of China (Grant Nos. 2013GB106001, 2013GB111002, 2015GB110001).

  14. [Fiftieth anniversary of the Medical Movement in Mexico (1964-1965)].

    PubMed

    Treviño-Becerra, Alejandro; García-Manzo, Norberto Treviño; Mota-Hernández, Felipe; Gutiérrez-Samperio, César; Cano-Valle, Fernando

    This Symposium highlights the recognition that this year reaches half a century of the Medical Movement (1964-1965), and 27 years of publishing the book titled, "Documental Memories and Reflections" ("Crónica Documental y Reflexiones") edited by the Faculty of Medicine of the UNAM, at that time directed by the prestigious Dr. Fernando Cano Valle. Our President Dr. Graue indicated that Dr. Alejandro Treviño-Becerra assumed the coordination of this session with the commitment to be published in the Medical Gazette of Mexico for current and future generations. The Academic participants were: Norberto Treviño García-Manzo, president of the Academy in 1988. Dr. Felipe Mota Hernández was the Recording Secretary of the Mexican Medical Alliance ("Alianza de Médicos Mexicanos"). Now he is the Dean of the Children's Hospital of Mexico "Federico Gómez". Dr. Cesar Gutiérrez Samperio, surgeon at IMSS and professor at Medicine School, University of Queretaro until a year ago. Dr. Fernando Cano Valle, former Head of the Medical Faculty, UNAM, presently a researcher in Medicine and Human Rights in the Institute for Juridical Research, UNAM. I quote the Academic Treviño Zapata: "I believe that it will be difficult to bring again the conditions and circumstances that made possible the vigorous realization of the Medical Movement, the enthusiastic and hopeful creation of the Mexican Medical Alliance, and the promising start and progress of the integration of the national medical union."

  15. SIDD: A Semantically Integrated Database towards a Global View of Human Disease

    PubMed Central

    Cheng, Liang; Wang, Guohua; Li, Jie; Zhang, Tianjiao; Xu, Peigang; Wang, Yadong

    2013-01-01

    Background A number of databases have been developed to collect disease-related molecular, phenotypic and environmental features (DR-MPEs), such as genes, non-coding RNAs, genetic variations, drugs, phenotypes and environmental factors. However, each of current databases focused on only one or two DR-MPEs. There is an urgent demand to develop an integrated database, which can establish semantic associations among disease-related databases and link them to provide a global view of human disease at the biological level. This database, once developed, will facilitate researchers to query various DR-MPEs through disease, and investigate disease mechanisms from different types of data. Methodology To establish an integrated disease-associated database, disease vocabularies used in different databases are mapped to Disease Ontology (DO) through semantic match. 4,284 and 4,186 disease terms from Medical Subject Headings (MeSH) and Online Mendelian Inheritance in Man (OMIM) respectively are mapped to DO. Then, the relationships between DR-MPEs and diseases are extracted and merged from different source databases for reducing the data redundancy. Conclusions A semantically integrated disease-associated database (SIDD) is developed, which integrates 18 disease-associated databases, for researchers to browse multiple types of DR-MPEs in a view. A web interface allows easy navigation for querying information through browsing a disease ontology tree or searching a disease term. Furthermore, a network visualization tool using Cytoscape Web plugin has been implemented in SIDD. It enhances the SIDD usage when viewing the relationships between diseases and DR-MPEs. The current version of SIDD (Jul 2013) documents 4,465,131 entries relating to 139,365 DR-MPEs, and to 3,824 human diseases. The database can be freely accessed from: http://mlg.hit.edu.cn/SIDD. PMID:24146757

  16. NCEA Scientists - Past and Present

    EPA Science Inventory

    Les Grant

    Photo of Dr. Les Grant

    Dr. Les Grant, Director of EPA's National Center for Environmental Assessment's Research Triangle Park Divisi...

  17. Approximation for Bayesian Ability Estimation.

    DTIC Science & Technology

    1987-02-18

    Leyden Air Force Human Resources Lab Education Research Center Brooks AFB, TX 78235 Boerhaavelsan 2 2334 EN Leyden Dr. kent Eaton The NETHERLANDS Army...Box 16268 Alexandria, VA 22302-0266 Ms. Kathleen Moreno Navy Personnel R&D Ce nter Dr. William L. Maloy Code 62 Chief of Naval Education San Diego

  18. NCI and the Chinese National Cancer Center pursue new collaborations in cancer research

    Cancer.gov

    CGH Director, Dr. Ted Trimble, and East Asia Program Director, Dr. Ann Chao, traveled to Beijing with Mr. Matthew Brown from the Department of Health and Human Services Office of Global Affairs to attend the Joint Meeting of the NCC and the U.S. NCI.

  19. Mapping International Cancer Activities – Global Cancer Project Map Launch

    Cancer.gov

    CGH’s Dr. Sudha Sivaram, Dr. Makeda Williams, and Ms. Kalina Duncan have partnered with Drs. Ami Bhatt and Franklin Huang at Global Oncology, Inc. (GO) to develop the Global Cancer Project Map - a web-based tool designed to facilitate cancer research and control activity planning.

  20. Dr. Israel Cuellar (1946-2008)

    ERIC Educational Resources Information Center

    Zamarripa, Manuel X.

    2009-01-01

    On September 7th, 2008, the mental health field lost a trailblazing researcher and clinician as he lost his battle with amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig's disease. Dr. Israel Cuellar made significant contributions to the study of acculturation including its importance in delivering appropriate mental health…

  1. 76 FR 66072 - Albert Ronald Cioffi: Debarment Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... unapproved drug derived from Botulinum Toxin Type A (TRI-toxin), sold by Toxin Research International (TRI... they were receiving an unapproved version of Botulinum Toxin Type A. Instead, Dr. Cioffi told patients... Florida, and elsewhere, Dr. Cioffi did misbrand a drug, namely Botulinum Toxin Type A distributed by TRI...

  2. Different Weather

    ERIC Educational Resources Information Center

    Stephens, Jonathan

    2007-01-01

    This article is a response to Rhoda Bernard's (2005) article, "Making Music, Making Selves". The author first met Dr. Bernard several years ago in the UK, at an international music education research conference at the University of Exeter. Without realising he was in the audience, Dr. Bernard cited his 1995 article "Artist or Teacher?" as an early…

  3. The life and legacy of Dr. Lee Baldwin

    USDA-ARS?s Scientific Manuscript database

    This paper outlines the life and legacy of the late Dr. Ransom L. Baldwin, V. The purpose was to highlight the impact his teaching and research had on the international energy and protein metabolism communities at their fourth international conference. The paper will be presented at the outset of ...

  4. Obituary: Herbert Gursky, 1930-2006

    NASA Astrophysics Data System (ADS)

    Doschek, George; Dahlburg, Jill

    2007-12-01

    Dr. Herbert Gursky, Acting Associate Director of Research for the Naval Research Laboratory's (NRL's) Systems Directorate, and formerly Superintendent of the Space Science Division and Chief Scientist of the E. O. Hulburt Center for Space Research. Dr. Gursky died following a long illness on late Friday afternoon, December 1, 2006. Dr. Gursky was a great friend, valued colleague, and distinguished researcher who will be missed greatly. Dr. Gursky was born in Bronx, New York, on May 27, 1930. He was educated in secondary schools in Miami, Florida, and received a Bachelor's Degree from the University of Florida in 1951. He did graduate work in physics at Vanderbilt University (Master's degree in 1953) and Princeton University (Doctorate degree in 1959). His first professional position was at Columbia University as an instructor in the Physics Department from 1958 to 1961. In 1961, he joined American Science and Engineering, Inc. (AS&E) in Cambridge, Massachusetts, as a senior scientist and rose to the position of Vice President, Space Research in 1967. In 1973 he joined the Smithsonian Astrophysical Observatory (SAO) as a supervisory astrophysicist. In 1974, Dr. Gursky was appointed Professor in the Practice of Astronomy at Harvard University and in 1976 was named Associate Director of the Center for Astrophysics for the Division of Optical and Infrared Astronomy. In 1981, Dr. Gursky joined NRL as Superintendent of its Space Science Division and Chief Scientist of the E. O. Hulburt Center for Space Research. He moved to the position of Acting Associate Director of Research for NRL's Systems Directorate in 2006. Dr. Gursky's primary research interests were in the area of X-ray astronomy. He published more than 100 articles in this area and edited two books on the subject. Before arriving at NRL, he was the principal investigator for NASA-sponsored space programs on the Astronomical Netherlands Satellite (ANS) and the High Energy Astrophysics Observatory (HEAO)-1 satellite, and a co-investigator on numerous other rocket and satellite experiments. At AS&E, Dr. Gursky managed research activities encompassing solar physics and magnetospheric research, and at SAO, he managed programs of ground-based astronomy and infrared astronomy. At SAO, he oversaw the completion of the Multiple Mirror Telescope, a joint program of SAO and the University of Arizona, comprising a 4.5-meter (equivalent) telescope of novel design that is situated at Mount Hopkins in Arizona. Dr. Gursky's work at NRL involved direction of a broad-ranging research effort involving about fifty Ph.D. scientists conducting investigations in the areas of high-energy astronomy, solar physics, solar terrestrial effects and atmospheric science. NRL is the corporate research laboratory for the Navy and has the responsibility for assuring that future Navy systems take full advantage of all available technology and scientific understandings. Dr. Gursky had the ability to distill and seize the most important nuggets from any research program and envision its application to a variety of new problems and directions. In numerous areas of atmospheric, solar and space science technology, Dr. Gursky recognized key scientific issues and their potential DoD applications. In solar physics, he spurred the development of semi-empirical modeling to predict solar storms that has been successfully transitioned to operational systems. He also supported participation in all NASA and other agency Sun-Earth connection orbiting space programs which resulted in a succession of spectacularly successful experiments in solar physics such as the high resolution rocket spectrograph and its flight on the NASA Spacelab 2, the Solar Ultraviolet Spectral Irradiance Monitor (SUSIM) on the NASA Upper Atmosphere Research Satellite, the Bragg crystal spectrometer solar flare experiment on the Japanese Yohkoh spacecraft, and the Large Angle and Spectrometric Coronagraph Experiment (LASCO) and extreme ultraviolet imaging telescope (EIT) on the ESA/NASA Solar and Heliospheric Observatory. These experiments have shed considerable light on how solar activity affects the near-Earth environment with many potential space weather applications. In high-energy astronomy, Dr. Gursky made many contributions. He provided scientific oversight for the Advanced Research and Global Observation Satellite (ARGOS) Space Test Program spacecraft that contained five NRL instruments: the Unconventional Stellar Aspect (USA) experiment, the Global Imaging Monitor of the Ionosphere (GIMI), the High Resolution Airglow/Aurora Spectroscopy (HIRAAS) experiment, the Extreme Ultraviolet Imaging Photometer (EUVIP), and the Coherent Electromagnetic Radio Tomography (CERTO) instrument. He continued his interest in X-ray astronomy with the USA experiment, which obtained observations of many celestial sources such as galactic binary X-ray sources and pulsars. Always with an eye toward applications, Dr. Gursky was interested in using X-ray sources, specifically X-ray pulsars, as precise clocks to provide spacecraft with autonomous timing and navigation. Dr. Gursky also supported research in gamma ray astrophysics, such as the development of NRL's Oriented Scintillation Spectrometer Experiment (OSSE) for the NASA Compton Gamma Ray Observatory (CGRO) satellite, and analysis of solar flare gamma ray spectra obtained from the NASA Solar Maximum Mission. In atmospheric science, Dr. Gursky particularly encouraged practical applications of basic research. He recognized the importance of remote sensing for space weather, which resulted in the development at NRL of operational ultraviolet sensors on Defense Meteorological Satellite Program (DMSP) spacecraft that are now providing environmental data products to the Air Force Space Weather Agency. He initiated a program in middle atmosphere research that has been enormously successful and has spawned numerous experimental and theoretical advances, such as the Middle Atmosphere High Resolution Spectrograph Investigation (MAHRSI) to measure trace constituents in the middle atmosphere such as the hydroxyl radical (OH). Dr. Gursky supported the development of theoretical middle atmosphere models such as the Mountain Wave Forecast Model that was used to predict flight conditions for allied aircraft during operations Southern Watch, Enduring Freedom, and Iraqi Freedom, which has been a boon to stratospheric flight operations over mountainous terrain. He also supported the HIRAAS experiment on ARGOS. Dr. Gursky provided outstanding leadership in the continued development of the United States space program. Under his stewardship, the NRL Space Science Division substantially expanded its leadership role in understanding the space environment and its effects on military and civilian systems. The Laboratory and the world are now witnessing the newest results of his scientific acumen and sound decision-making as exemplified in the very recent successful completions and launches of these major Space Science Division instruments: Delivery of GLAST LAT (September 2006): Delivery of the collaborative NRL Large Area Telescope (LAT) for the NASA Gamma Ray Large Area Space Telescope (GLAST) satellite integration; when deployed, GLAST will measure the most energetic processes in the universe — from X-ray bursts, black holes, neutron stars, and solar flares — and has the potential to discover previously unknown relics of the Big Bang; Launch of SOLAR-B (September 2006): The Japan Aerospace Exploration Agency's Hinode (Japanese for Sunrise, formerly known as SOLAR-B) launched September 23 carrying NRL's collaborative Extreme-ultraviolet Imaging Spectrometer (EIS), which achieved first light on October 28. EIS is now observing emission lines produced by highly ionized elements in the solar coronal and upper transition region of the Sun's atmosphere. Space Science Division scientists expect much exciting science concerning the coupling of solar activity to the near-Earth space environment to be produced by the EIS instrument; and, Launch of STEREO (October 2006): NASA's Solar Terrestrial Relations Observatory (STEREO) launched 25 October, carrying the collaborative NRL Sun-Earth Connection Coronal and Heliospheric Investigation (SECCHI) instruments suite, which is currently successfully functioning in the pre-commissioning phase. The instruments onboard STEREO's twin spacecraft will make observations to help NRL researchers construct the first-ever three-dimensional views of coronal mass ejections, vital data — in complement with the long-operational NRL-built NASA LASCO — for understanding how the Sun creates space weather Perhaps Dr. Gursky's most personal research successes were as a member of the group that made the discovery of cosmic X-ray sources in 1961, his work with sounding rockets that culminated in the optical identification of the bright X-ray source Scorpius X1 in 1966, his work on clusters of galaxies and the diffuse X-ray background from the Uhuru Satellite and the discovery of X-ray bursters on the ANS satellite.

  5. KSC-94PC-0901

    NASA Image and Video Library

    1994-07-20

    KENNEDY SPACE CENTER, FLA. -- Dr. Irene Duhart Long is the director, Biomedical Operations and Research Office, at the Kennedy Space Center effective July 24, 1994. She is responsible for the program management of the center's aerospace and occupational medicine, life sciences research, environmental health programs and the operations management of the life sciences support facilities. Dr. Long also is responsible for providing the coordinating medical, environmental monitoring and environmental health support to launch and landing activities and day-to-day institutional functions.

  6. A System Approach to Adaptive Multi-Modal Sensor Designs

    DTIC Science & Technology

    2010-02-01

    afosr.af.mil> Prepared for Air Force Office of Scientific Research under Award FA9550-08-1-0199 February 2010 The City College of New York...York, NY 10031 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) Dr. Douglas Cochran AFOSR Air ...RIT. We would also like to thank Dr. Erik Blasch at the Air Force Research Laboratory (AFRL/RYAA) for his collaboration when our PhD student Mr

  7. A Stress Analysis of Circular Cylindrical Shell Intersections, Including the Influences of Reinforcement, Cyclic Plasticity and Fatigue.

    DTIC Science & Technology

    1980-12-01

    Professor Paul M. Naghdi National Academy of Sciences University of California National Research Council Department of Mechanical Engineering Ship Hull...Angeles, California 90024 Department of Mechanical Engineering Washington, D.C. 20064 Professor Burt Paul University of Pennsylvania Dr. Samuel B...78u4 74 -6 19 Universities (Con’t) Universities (Con’t) Dr. V. K. Varadan Professor V. H. Neubert Ohio State University Research Foundation Pennsylvania

  8. Phoenix, a High-Performance UNIX with an Emphasis on Dynamic Modification, Real-Time Response and Survivability

    DTIC Science & Technology

    1990-01-12

    Communications COM-28, (April 1980 ) 425-432. [6] Munch-Anderson, B. and T.U. Zahle, Scheduling According to Job Priority With Prevention of Deadlock and...Interconnection, IEEE Transactions on Communications COM-28, (April 1980 ) 425-432. (4] Cook, R.P., StarMod, A Language for Distributed Programming...Research Triangle Park, NC 27709-2211 Attention: Dr. David W. Hislop * Electronics Division 51 Dr. David W. Hislop Electronics Division U. S. Army Research

  9. Electrochemistry and Spectroelectrochemistry of Polynuclear Zinc Phthalocyanines: Formation of Mixed Valence Cation Radical Species.

    DTIC Science & Technology

    1988-02-25

    No. No. Copies Cpe Office of Naval Research 2 Dr. David You.)g Attn: Code 1113 Code 334 800 N. Quinc’ Street NORDA Arlington, Virginia 22217-5000 NSTL...Naval Surface Weapons Center Chapel Hill, North Carolina 27514 Silver Spring, Maryland 20910 Or. R. A. Marcus Dr. Michael J. Weaver Department of...Microprocessor model 340 spectrometer. Cyclic and dif, rential pulse voltammetry were performed with a Princeton Applied Research (PARC) model 174A

  10. Meeting Jentschke

    ScienceCinema

    None

    2018-05-18

    After an introduction about the latest research and news at CERN, the DG W. Jentschke speaks about future management of CERN with two new general managers, who will be in charge for the next 5 years: Dr. J.B. Adams who will focus on the administration of CERN and also the construction of buildings and equipment, and Dr. L. Van Hove who will be responsible for research activities. The DG speaks about expected changes, shared services, different divisions and their leaders, etc.

  11. Dr. Hugh L. Dryden - portrait

    NASA Technical Reports Server (NTRS)

    1959-01-01

    Dr. Hugh Latimer Dryden, had many titles after his name in his lifetime. In 1949 he became the director of the National Advisory Committee for Aeronautics (NACA). Dr. Dryden received many accolades and awards both during his life and after his death, but the greatest and most appropriate honor came on March 26, 1976, when NASA renamed the NASA Flight Research Center as the NASA Hugh L. Dryden Flight Research Center. At the dedication ceremony NASA Administrator James C. Fletcher stated: 'in 1924, when the fastest racing planes did well to fly at 280 m.p.h., Dryden was already probing the transonic range of . . . flight. Later in the 1920s, he sought to develop methods of accurately measuring . . . turbulence in wind tunnels. In 1938 he was the first American to deliver the Wright Brothers lecture. His 'Turbulence and the Boundary Layer' became a classic summary on the subject. It is most fitting that this Flight Research Center, with its unique and highly specialized capability for solving aerospace problems, should memorialize the genius of Hugh Dryden.' Dr. Dryden was initially an aerodynamicist with the National Bureau of Standards. He did important early work in high-speed aerodynamics. In 1947 he became the director of aeronautical research for the NACA (a predecessor of the National Aeronautics and Space Administration). Two years later, he became NACA's director, a position he held until 1958 when he became deputy administrator of NASA.

  12. Commentary: taking a deep breath before reflecting on differential response.

    PubMed

    Merkel-Holguin, Lisa; Bross, Donald C

    2015-01-01

    Although there are certainly limitations to each and every research and evaluation project in child welfare, as with other fields of study, understanding DR as a CPS reform has been fostered through many thoughtful and rigorous studies that have employed random control trial evaluation designs. For each assumption addressed in this commentary, we have raised a few questions. For all interested in CPS reform, other questions arise because child protection and child welfare professionals are trying to encourage more scientific ways of thinking as a means of engendering improvements: 1. Has the research on DR spotlighted the inadequacy of CPS interventions, either AR or IR? A high percentage of CPS responses are short-term. Is it reasonable to expect significant differences between AR and IR families and improvements in the CPS population, given that families often present with problems characterized as intractable but the intensity of the CPS response, coupled with limited service availability and accessibility, may not be sufficient to meet family needs? 2. Has the DR research, which has mainly focused on AR families, also highlighted the glaring absence of quality research in what is effective in producing positive outcomes for families that receive traditional child abuse and neglect investigations? 3. Does the implementation of DR move the CPS field ahead in terms of making better triage decisions, identifying especially those that require CPS involvement as compared to those who will benefit from but might not absolutely need intervention? Is 'triage' an explicit assumption of the DR innovation? Is it an implicit assumption of DR, however defined? If triage is not part of the research, does the ability of child protection to respond both differentially and also correctly to cases needing most, some, or no attention remain unknown? Until there is a reliable and valid way for determining for which families services are most urgently needed, are many reforms in CPS at risk of not producing the outcomes desired? 4. Are there other unintended consequences of either accepting or rejecting DR that might not have been considered? Our current perspective is to state the obvious and point out that rarely are scientifically or "evidence-based" changes in practice achieved or discredited in a decade or two, much more a scant few years. Breathing deeply from time to time, and even pausing for reflection once in awhile, are useful habits for taking on long-range and difficult human endeavors.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chu, Steven

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadershipmore » as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.« less

  14. Successes and Challenges of Vaccines to Prevent HPV-associated Cancers

    Cancer.gov

    Dr. John T. Schiller received his bachelor’s degree in Molecular Biology from the University of Wisconsin, Madison in 1975, and his master’s and PhD degrees in Microbiology from the University of Washington, Seattle, in 1978 and 1982, respectively. He is currently a NIH Distinguished Investigator and Section Chief in the Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, Bethesda, MD. In his 35 years at the NCI, Dr. Schiller has studied various aspects of papillomavirus molecular biology, immunology, and epidemiology The laboratory headed by Dr. Schiller and Dr. Lowy led in the discovery, characterization, and clinical testing of virus-like particle (VLP) vaccines to prevent the HPV infections that cause cervical and other cancers. They have facilitated technology transfer to potential HPV vaccine manufactures in developing countries and provided leadership in promoting global public health issues related to the implementation of HPV vaccination. They have received numerous awards for this work including the 2007 Sabin Gold Medal Award, the 2014 National Medal of Technology and Innovation, and the 2017 Lasker~DeBakey Clinical Medical Research Award. Dr. Schiller’s current interests include basic studies of papillomavirus virion assembly and infection, the development of 2 generation HPV vaccines, and vaccines and therapies for other infectious diseases and cancers.  

  15. "Can HIV be eradicated from an infected individual?" Piot, Ho and scientific community meet at 4th Retroviral Conference.

    PubMed

    Macinnis R

    1997-01-01

    More than 2300 medical and scientific professionals attended the 4th Conference on Retroviruses and Opportunistic Infection held in Washington, DC, during January 22-26, 1997, to discuss the latest information on treatment for HIV/AIDS and opportunistic infections. The keynote speakers were Dr. David Ho, a researcher at the Aaron Diamond AIDS Institute, and Dr. Peter Piot, Director of UNAIDS. Dr. Ho told the audience that reasons exist to be hopeful about prolonging the life of people with AIDS even though HIV has not yet been eliminated from any infected individual. He urged the media to carefully and accurately portray HIV/AIDS, and stressed that there is no cure for AIDS and that safer sex practices should be maintained in order to prevent the sexual transmission of HIV. In his address, Dr. Piot considered how HIV/AIDS treatment and care options translate to the reality of developing countries in which 90% of all HIV/AIDS cases reside. Recognizing researchers' accomplishments in developing treatment therapies against HIV/AIDS, Piot urged them to focus upon the development of preventive technology, including microbicides, vaccines, and a way to prevent mother-to-fetus HIV transmission. Dr. Piot also discussed a proposed UNAIDS plan to make advanced therapies against HIV/AIDS available in developing countries.

  16. A portrait of prefrontal lobotomy performed at the Royal Prince Alfred Hospital in Sydney by Dr Rex Money.

    PubMed

    White, Richard T; McGee-Collett, Martin

    2016-10-01

    The objective of this article is to provide a portrait of prefrontal lobotomy performed at the Royal Prince Alfred Hospital, Sydney by the Head of Neurosurgery Dr Rex Money and to describe Dr Money's role in the promotion of psychosurgery in Sydney. We draw attention to an oral presentation by Dr Rex Money in 1951, a journal article written by Money, archival information held at the Royal Prince Alfred Hospital, including Dr Money's accounts of his travels and his reports regarding neurosurgery - both internationally and in Australia. Dr Rex Money performed a series of 13 prefrontal lobotomies between 1945 and 1951, and presented the theoretical basis for his series, his operative procedures and the outcomes at the annual meeting of its medical officers' association. Notwithstanding various deficiencies in his clinical research, Money's descriptions give a relatively comprehensive account of one of the first series of prefrontal lobotomies performed in Australia. The current article also describes Dr Money's contributions to the promotion of psychosurgery in Sydney, and illustrates the participation of a senior neurosurgeon and of a major Sydney teaching hospital during the psychosurgery saga. © The Royal Australian and New Zealand College of Psychiatrists 2016.

  17. UPR/Mayaguez High Energy Physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mendez, Hector

    This year the University of Puerto Rico at Mayaguez (UPRM) High Energy Physics (HEP) group continued with the ongoing research program outlined in the grant proposal. The program is centered on the Compact Muon Solenoid (CMS) experiment at the proton-proton (pp) collisions at the Large Hadron Collider (LHC) at CERN in Geneva, Switzerland. The main research focus is on data analysis and on the preparation for the High Luminosity (HL) LHC or experiment detector upgrade. The physics data analysis included Higgs Doublet Search and measurement of the (1) Λ 0 b branching fraction, (2) B meson mass, and (3) hyperonmore » θ - b lifetime. The detector upgrade included work on the preparations for the Forward Pixel (FPIX) detector Silicon Sensor Testing in a production run at Fermilab. In addition, the group has taken responsibilities on the Software Release through our former research associate Dr. Eric Brownson who acted until last December as a Level Two Offline Manager for the CMS Upgrade. In support of the CMS data analysis activities carried out locally, the UPRM group has built and maintains an excellent Tier3 analysis center in Mayaguez. This allowed us to analyze large data samples and to continue the development of algorithms for the upgrade tracking robustness we started several years ago, and we plan to resume in the near future. This project involves computer simulation of the radiation damage to be suffered at the higher luminosities of the upgraded LHC. This year we continued to serve as a source of outstanding students for the field of high energy physics. Three of our graduate students finished their MS work in May, 2014, Their theses research were on data analysis of heavy quark b-physics. All of them are currently enrolled at Ph.D. physics program across the nation. One of them (Hector Moreno) at New Mexico University (Hector Moreno), one at University of New Hampshire (Sandra Santiesteban) and one at University of Puerto Rico-Rio Piedras (Carlos Malca). The students H. Moreno and C. Malca has been directly supervised by Dr. Mendez and S. Santiesteban supervised by Dr. Ramirez. During the last 13 years, our group have graduated 23 MS students on experimental High Energy Physics data analysis and applied hardware techniques. Most of the students have been supported by DOE grants, included this grant. Since 2001, Dr. Mendez have directly supervised eleven students, Dr. Ramirez three students and the former PI (Dr. Lopez) nine students. These theses work are fully documented in the group web page (http://charma.uprm.edu). The High Energy Physics group at Mayaguez is small and presently consists of three Physics faculty members, the Senior Investigators Dr. Hector Mendez (Professor) and Dr. Juan Eduardo Ramirez (Professor), and Dr. Sudhir Malik who was just hired in July 2014. Dr. Ramirez is in charge of the UPRM Tier-3 computing and will be building the network bandwidth infrastructure for the campus, while Dr. Mendez will continues his effort in finishing the heavy quark physics data analysis and moving to work on SUSY analysis for the 2015 data. Our last grant application in 2012 was awarded only for 2013-2014. As a result our postdoc position was lost last month of March. Since then, we have hired Dr. Malik as a new faculty in order to reinforce the group and to continue our efforts with the CMS experiment. Our plan is to hire another junior faculty in the next two years to strengthen the HEP group even further. Dr. Mendez continues with QuarkNet activities involving an ever larger group of high school physics teachers from all around Puerto Rico.« less

  18. Magnetic Earth Ionosphere Resonant Frequencies

    NASA Technical Reports Server (NTRS)

    Spaniol, Craig

    1994-01-01

    The Community College Division is pleased to report progress of NASA funded research at West Virginia State College. During this reporting period, the project research group has continued with activities to develop instrumentation capability designed to monitor resonant cavity frequencies in the atmospheric region between the Earth's surface and the ionosphere. In addition, the project's principal investigator, Dr. Craig Spaniol, and NASA technical officer, Dr. John Sutton, have written and published technical papers intended to expand the scientific and technical framework needed for project research. This research continues to provide an excellent example of government and education working together to provide significant research in the college environment. This cooperative effort has provided many students with technical project work which compliments their education.

  19. 75 FR 11375 - Revision of Fee Schedules; Fee Recovery for FY 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... Spent Fuel Storage/Reactor Decommissioning..... 2.7 0.2 0.2 Test and Research Reactors 0.2 0.0 0.0 Fuel... categories of licenses. The FY 2009 fee is also shown for comparative purposes. Table V--Rebaselined Annual...) Spent Fuel Storage/Reactor 122,000 143,000 Decommissioning Test and Research Reactors (Non-power 87,600...

  20. Safety Issues at the DOE Test and Research Reactors. A Report to the U.S. Department of Energy.

    ERIC Educational Resources Information Center

    National Academy of Sciences - National Research Council, Washington, DC. Commission on Physical Sciences, Mathematics, and Resources.

    This report provides an assessment of safety issues at the Department of Energy (DOE) test and research reactors. Part A identifies six safety issues of the reactors. These issues include the safety design philosophy, the conduct of safety reviews, the performance of probabilistic risk assessments, the reliance on reactor operators, the fragmented…

  1. Bibliography of Doctor Chul Park

    NASA Technical Reports Server (NTRS)

    Gochberg, Lawrence A.; Venkatapathy, Ethiraj; Park, Chul

    1995-01-01

    This document contains a comprehensive bibliography of the published works, and a short biography, of Dr. Chul Park. The contents of this bibliography were compiled primarily from the NASA RECON data base. The RECON citations have been modified to appear in a uniform format with all other listed citations . These other citations were located by computer searches in the INSPEC, NTIS, COMPENDEX, and Chemical Abstracts data bases, as well as through the cooperation of Dr. Chul Park, and his associates in the Reacting Flow Environments Branch at NASA Ames Research Center. All citations are presented in an approximate reverse chronological order from the present date. This work was created to honor the occasion of Dr. Chul Park's retirement on December 14, 1994, after 27 years of distinguished government service at the NASA Ames Research Center.

  2. Ethnic Differences in the Prevalence of Diabetic Retinopathy in Persons With Diabetes When First Presenting at a Diabetes Clinic in South Africa

    PubMed Central

    Thomas, Rebecca L.; Distiller, Larry; Luzio, Stephen D.; Chowdhury, Sharmistha Roy; Melville, Vanessa J.; Kramer, Brian; Owens, David R.

    2013-01-01

    OBJECTIVE To describe the prevalence and associated risk factors for diabetic retinopathy (DR) within a multiethnic population at presentation to a diabetes clinic in South Africa. RESEARCH DESIGN AND METHODS Retinal photography was conducted using a nonmydriatic digital camera without mydriasis and graded by one of three senior graders. Logistic regression analyses were used to assess the association between any DR, referable DR, and clinical risk factors. RESULTS A total of 1,537 persons with type 1 and 3,978 with type 2 diabetes were included. Prevalence of any DR in type 1 diabetes was 35.2% (background DR 26% and referable DR 9.2%) and in type 2 diabetes was 20.5% (14.1 and 6.4%, respectively). In type 1 diabetes, there was an increased risk of any DR in Asian Indians, whereas the risk of referable DR was increased for indigenous Africans compared with Caucasians. In type 2 diabetes, the risk was increased for all non-Caucasians compared with Caucasians. Longer duration of diabetes and elevated HbA1c were independently associated with any and referable DR in both type 1 and type 2 diabetes, with the addition of hypertension and smoking in type 1 diabetes when adjusted for age at diagnosis of diabetes, sex, and ethnicity. CONCLUSIONS The prevalence of DR in this population from South Africa was similar to that reported globally; however, ethnic differences were observed. Increasing duration of diabetes and poor glycemic control were the strongest risk factors associated with any and referable DR in both type 1 and type 2 diabetes. PMID:23033236

  3. The medical ethics of the 'father of gynaecology', Dr J Marion Sims.

    PubMed Central

    Ojanuga, D

    1993-01-01

    Vesico-vaginal fistula (VVF) was a common ailment among American women in the 19th century. Prior to that time, no successful surgery had been developed for the cure of this condition until Dr J Marion Sims perfected a successful surgical technique in 1849. Dr Sims used female slaves as research subjects over a four-year period of experimentation (1845-1849). This paper discusses the controversy surrounding his use of powerless women and whether his actions were acceptable during that historical period. PMID:8459435

  4. Dr. Kenneth Plotkins Myriad Contribution to the National Aeronautics and Space Administrations Supersonic Mission

    NASA Technical Reports Server (NTRS)

    Haering, Edward A.

    2017-01-01

    The world as a whole and NASA in particular, owes a large debt of gratitude to Dr. Kenneth Plotkin for his decades of service in the field of sonic boom research and advancement of quiet supersonic transportation. This presentation will highlight the contributions of Dr. Plotkin to a myriad of NASA projects. One of the largest efforts was the assembly and continual improvement of sonic boom propagation software tools, collectively called PCBoom, which allowed the analysis of real and imagined vehicles from Mach cutoff conditions to the hypersonic.

  5. Reflections on a life in biomedicine: leading change.

    PubMed

    Nabel, Elizabeth G

    2013-09-01

    Dr. Elizabeth Nabel delivered the following presentation as the Lee E. Farr Lecturer on May 7, 2013, which served as the culmination of the annual Student Research Day at Yale School of Medicine. Dr. Nabel is President of the Brigham and Women's Hospital in Boston, Massachusetts, and Professor of Medicine at Harvard Medical School. Her lecture to Yale medical students portrayed her own personal and professional journey through medicine as a series of opportunities. Dr. Nabel focused on the roles and responsibilities of physicians to recognize need and to make change through focused advocacy.

  6. VII International Congress of Engineering Physics

    NASA Astrophysics Data System (ADS)

    2015-01-01

    In the frame of the fortieth anniversary celebration of the Universidad Autónoma Metropolitana and the Physics Engineering career, the Division of Basic Science and Engineering and its Departments organized the "VII International Congress of Physics Engineering". The Congress was held from 24 to 28 November 2014 in Mexico City, Mexico. This congress is the first of its type in Latin America, and because of its international character, it gathers experts on physics engineering from Mexico and all over the globe. Since 1999, this event has shown research, articles, projects, technological developments and vanguard scientists. These activities aim to spread, promote, and share the knowledge of Physics Engineering. The topics of the Congress were: • Renewable energies engineering • Materials technology • Nanotechnology • Medical physics • Educational physics engineering • Nuclear engineering • High precision instrumentation • Atmospheric physics • Optical engineering • Physics history • Acoustics This event integrates lectures on top trending topics with pre-congress workshops, which are given by recognized scientists with an outstanding academic record. The lectures and workshops allow the exchange of experiences, and create and strengthen research networks. The Congress also encourages professional mobility among all universities and research centres from all countries. CIIF2014 Organizing and Editorial Committee Dr. Ernesto Rodrigo Vázquez Cerón Universidad Autónoma Metropolitana - Azcapotzalco ervc@correo.azc.uam.mx Dr. Luis Enrique Noreña Franco Universidad Autónoma Metropolitana - Azcapotzalco lnf@correo.azc.uam.mx Dr. Alberto Rubio Ponce Universidad Autónoma Metropolitana - Azcapotzalco arp@correo.azc.uam.mx Dr. Óscar Olvera Neria Universidad Autónoma Metropolitana - Azcapotzalco oon@correo.azc.uam.mx Professor Jaime Granados Samaniego Universidad Autónoma Metropolitana - Azcapotzalco jgs@correo.azc.uam.mx Dr. Roberto Tito Hernández López Universidad Autónoma Metropolitana - Azcapotzalco hlrt@correo.azc.uam.mx Dr. Anatolio Martínez Jiménez Universidad Autónoma Metropolitana - Azcapotzalco amartinez@correo.azc.uam.mx Dr. Eusebio Guzmán Serrano Universidad Autónoma Metropolitana - Azcapotzalco gse@correo.azc.uam.mx

  7. Collected Papers in Structural Mechanics Honoring Dr. James H. Starnes, Jr.

    NASA Technical Reports Server (NTRS)

    Knight, Norman F., Jr. (Compiler); Nemeth, Michael P. (Compiler); Malone, John B. (Compiler)

    2006-01-01

    This special publication contains a collection of structural mechanics papers honoring Dr. James H. Starnes, Jr. presented at the 46th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference held in Austin, Texas, April 18-21, 2005. Contributors to this publication represent a small number of those influenced by Dr. Starnes' technical leadership, his technical prowess and diversity, and his technical breath and depth in engineering mechanics. These papers cover some of the research areas Dr. Starnes investigated, which included buckling, postbuckling, and collapse of structures; composite structural mechanics, residual strength and damage tolerance of metallic and composite structures; and aircraft structural design, certification and verification. He actively pursued technical understanding and clarity, championed technical excellence, and modeled humility and perseverance.

  8. 2016 Research Outreach Program report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Hye Young; Kim, Yangkyu

    2016-10-13

    This paper is the research activity report for 4 weeks in LANL. Under the guidance of Dr. Lee, who performs nuclear physics research at LANSCE, LANL, I studied the Low Energy NZ (LENZ) setup and how to use the LENZ. First, I studied the LENZ chamber and Si detectors, and worked on detector calibrations, using the computer software, ROOT (CERN developed data analysis tool) and EXCEL (Microsoft office software). I also performed the calibration experiments that measure alpha particles emitted from a Th-229 source by using a S1-type detector (Si detector). And with Dr. Lee, we checked the result.

  9. Coupled Research in Ocean Acoustics and Signal Processing for the Next Generation of Underwater Acoustic Communication Systems

    DTIC Science & Technology

    2016-08-05

    JPAnalytics LLC CC: DCMA Boston DTIC Director, NRL Progress Report #8 Coupled Research in Ocean Acoustics and Signal Processing for the Next...Generation of Underwater Acoustic Communication Systems Principal Investigator’s Name: Dr. James Preisig Period Covered By Report: 1/20/2016 to 4/19/2016...Technical work this period has spanned two areas. The first of these is VHF Acoustics . During this time period, the Principle Investigator worked with Dr

  10. Development of a Space Flight Prototype Doppler Asymmetric Spatial Heterodyne (DASH) Spectrometer for the Measurement of Upper Atmospheric Winds

    DTIC Science & Technology

    2011-10-31

    required for space flight. Dr. John Hughes and Dr. Abas Sivjee of Embry-Riddle Aeronautical University in Daytona FL and all the staff at the HAARP ...Laboratory, was conducted at the High Frequency Active Auroral Research Program ( HAARP ) facility in Alaska. ARROW was shipped to Anchorage AK from...the Naval Research Laboratory in Washington DC and was delivered, installed, and run at the HAARP facility by ARTEP Inc. personnel. The field

  11. Ancient Earth, Alien Earths Event

    NASA Image and Video Library

    2014-08-20

    Dr. Shawn Domagal-Goldman, Research Space Scientist, NASA Goddard Space Flight Center, speaks on a panel at the “Ancient Earth, Alien Earths” Event at NASA Headquarters in Washington, DC Wednesday, August 20, 2014. The event was sponsored by NASA, the National Science Foundation (NSF), and the Smithsonian Institution and was moderated by Dr. David H. Grinspoon, Senior Scientist at the Planetary Science Institute. Six scientists discussed how research on early Earth could help guide our search for habitable planets orbiting other stars. Photo Credit: (NASA/Aubrey Gemignani)

  12. Hearings Before the Select Committee on Nutrition and Human Needs of the United States Senate, Ninety-Second Congress, First Session on Nutrition and Human Needs. Part 10--Micronutrient Supplements for School Lunch Program. Hearings Held Washington, D.C., December 7, 1971.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Select Committee on Nutrition and Human Needs.

    Contents of these hearings include the statement and testimony of the following witnesses: (1) Alan Young, Research Administrator, Research and Development Division, A. H. Robins Co.; Chairman, Board of Directors, Vitamin Information Bureau; (2) Dr. Joseph M. White, Nutritional and Medical Consultant, Miles Laboratories; (3) Dr. George Briggs,…

  13. Proceedings of the Meeting of the Coastal Engineering Research Board (56th) Held in Newport, Oregon on 9-11 June 1992

    DTIC Science & Technology

    1993-07-01

    conducts research in wave-structure struction productivity, interaction, rubble-mound structure behavior, and ocean wave measurement systems . He teaches ...North Bend, OR Dr. William G. McDougal , Oregon State Court Reporter University, Corvallis, OR Ms. Dale N. Milford, Certi-Comp Court Dr. William J...first mental problems as they arose. Generally briefly review our R&D system , particularly these problems are outside the scope of the portions dealing

  14. Proceedings of the NATO Radiological Human Response Subject Matter Expert Review Meeting, 26 June 2008, Albuquerque, New Mexico, United States of America

    DTIC Science & Technology

    2009-08-01

    the proposed general casualty estimation process. The next two briefings described the technical details of the development and content of the...Forces Radiobiological Research Institute (AFRRI) Dr. Gene McClellan, Applied Research Associates (ARA) COL John Mercier, AFRRI Dr. Kyle Millage...marrow damage occurs; lethality ranges from LD50/60 to LD99/60; death occurs within 3.5 to 6 weeks with the radiation injury alone but is accelerated

  15. VIDEO: Dr. Henry Rodriguez - Proteogenomics in Cancer Medicine | Office of Cancer Clinical Proteomics Research

    Cancer.gov

    Dr. Henry Rodriguez, director of the Office of Cancer Clinical Proteomics Research (OCCPR) at NCI, speaks with ecancer television at WIN 2017 about the translation of the proteins expressed in a patient's tumor into a map for druggable targets. By combining genomic and proteomic information (proteogenomics), leading scientists are gaining new insights into ways to detect and treat cancer due to a more complete and unified understanding of complex biological processes.

  16. ONRASIA Scientific Information Bulletin. Volume 17, Number 2, Apr-Jun 1992

    DTIC Science & Technology

    1992-06-01

    the Physics Division, Research 7. K Yagi, H . Onuki , S. Sugiyama, Department. Dr. Rehn received his andT. Yamazaki,BunkyoKenkyu 40(5) B.A. in physics at...Pittsburgh in 1962. Aftercomplet- 8. T. Saito, K Katori, M. Nishi, and ing his thesis research in nuclear H . Onuki , Rev. Sci. Instru. 60, 2303...quadrupole resonance studies of para (1989); T. Saito, K Katori, and H . Onuki , dichlorobenzene and related mate- Physica Scripta 41,783 (1990). rials, Dr. Rchn

  17. Bringing Gravity to Space

    NASA Technical Reports Server (NTRS)

    Norsk, P.; Shelhamer, M.

    2016-01-01

    This panel will present NASA's plans for ongoing and future research to define the requirements for Artificial Gravity (AG) as a countermeasure against the negative health effects of long-duration weightlessness. AG could mitigate the gravity-sensitive effects of spaceflight across a host of physiological systems. Bringing gravity to space could mitigate the sensorimotor and neuro-vestibular disturbances induced by G-transitions upon reaching a planetary body, and the cardiovascular deconditioning and musculoskeletal weakness induced by weightlessness. Of particular interest for AG during deep-space missions is mitigation of the Visual Impairment Intracranial Pressure (VIIP) syndrome that the majority of astronauts exhibit in space to varying degrees, and which presumably is associated with weightlessness-induced fluid shift from lower to upper body segments. AG could be very effective for reversing the fluid shift and thus help prevent VIIP. The first presentation by Dr. Charles will summarize some of the ground-based and (very little) space-based research that has been conducted on AG by the various space programs. Dr. Paloski will address the use of AG during deep-space exploration-class missions and describe the different AG scenarios such as intra-vehicular, part-of-vehicle, or whole-vehicle centrifugations. Dr. Clement will discuss currently planned NASA research as well as how to coordinate future activities among NASA's international partners. Dr. Barr will describe some possible future plans for using space- and ground-based partial-G analogs to define the relationship between physiological responses and G levels between 0 and 1. Finally, Dr. Stenger will summarize how the human cardiovascular system could benefit from intermittent short-radius centrifugations during long-duration missions.

  18. Quantitative Image Recovery From Measured Blind Backscattered Data Using a Globally Convergent Inverse Method

    DTIC Science & Technology

    2012-01-01

    research interests include in- 794 verse problems related to superresolution imaging and metamaterial design. 795 Dr. Fiddy is a Fellow of the Optical...verse problems related to superresolution imaging and metamaterial design. 795 Dr. Fiddy is a Fellow of the Optical Society of America, the IOP, and The

  19. Todd G. Deutsch | NREL

    Science.gov Websites

    page. Research Interests Solar energy conversion to hydrogen fuel via PEC water splitting III-V ://orcid.org/0000-0001-6577-1226 Dr. Deutsch has been studying photoelectrochemical (PEC) water splitting since semiconductor water-splitting systems under the joint guidance of Dr. Turner and Prof. Carl A. Koval in the

  20. Low Power Monolayer MoS2 Transistors for RF Applications

    DTIC Science & Technology

    2015-03-24

    techniques. Some of this was done in-house, while others were done in collaboration with Dr. Madan Dubey’s team at the Army Research Laboratories...quality. In our work we have used a combination of room temperature and low temperature Raman and PL mapping (collaboration with Dr Madan Dubey’s lab

  1. Severity Levels and Symptoms Complexes for Acute Radiation Sickness -- Description and Quantification

    DTIC Science & Technology

    1985-11-30

    of military task performance levels. This effort was performed under the guidance and direction of DNA staff members Dr. David Auton and Dr. Robert W...INC ATTN: J HOWE ATTN: S SHRIER HORIZONS TECHNOLOGY, INC S-CUBEDATTN: B PYATT ATTN: J PALMER I:T RESEARCH INSTITUTE SCIENCE APPLICATIONS INTL CORP

  2. Medical Training Aid

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Dr. Steven S. Saliterman developed his Dynacath Critical Care Patient Simulator as a training system for medical personnel involved in critical care management and hemodynamic monitoring. The system incorporates NASA simulation technology and allows hospitals and medical manufacturers to conduct training away from the patient's bedside. Dr. Saliterman was formerly employed by Ames Research Center and Johnson Space Center.

  3. Acquisition of Thermal Gravimetric Analyzer and Differential Scanning Calorimeter for Enhancing Science and Engineering Education and DOD-relevant research at Miami University

    DTIC Science & Technology

    2014-11-07

    of novel papers TGA Student project; synthesis. Moringa Seed Extract for novel coagulant for water treatment Biopolymer...Reason for Use Dr. Justin Saul Keratin hydro_gel for novel adsorbent DSC Senior Design; synthesis. Education Dr. Jason Moringa Seed Extract for novel

  4. Vance Berger, PhD | Division of Cancer Prevention

    Cancer.gov

    Dr. Vance Berger completed his PhD in statistics at Rutgers University in 1995, and then began working at the FDA. This is where he developed his research focus on biases and threats to the validity of medical studies, especially clinical trials. In 1999, Dr. Berger joined the NCI, and has remained ever since. |

  5. Improving College Students English Learning with Dr. Eye Android Mid

    ERIC Educational Resources Information Center

    Yang, Ju Yin; Che, Pei-Chun

    2015-01-01

    This paper investigates college students' English language learning through use of Dr. Eye Android handheld mobile Internet device (MID). Compared to related studies, students' English learning using MIDs has not been evaluated and fully understood in the field of higher education. Quantitatively, the researchers used TOEIC pretest and posttest to…

  6. Advanced Digital Communication Research.

    DTIC Science & Technology

    1985-07-01

    w-. r-7 -. .-. ,- - ; -" -r w- ,’, V" vr . V --. w-- . - -.’ ; U - ’- ’ ’’ . e ’ " . r. " - ’. -°~1 8 " * Scholtz, R.A., "Pseudonoise...Jet Propulsion Laboratory. Dr. Robert McEliece, California Institute of Technology. Dr. Seymour Stein, SCPE, Inc. 9 PM: Cinema Treats from the USC

  7. Asad Umar, DVM, PhD | Division of Cancer Prevention

    Cancer.gov

    Dr. Asad Umar received his PhD in Biochemistry and Immunology at the Johns Hopkins University in Baltimore, MD, in 1993. He conducted his postdoctoral training in the laboratories of Patricia Gearhart in Baltimore, MD and Thomas Kunkel at the National Institutes of Environmental Health Sciences in Research Triangle Park, NC. Dr. |

  8. Dr. Anna Stefanopoulou as Panelist and Presenter at SAE 2016

    Science.gov Websites

    Government/Industry Meeting ARC Automotive Research Center Home Page HOME PAGE ABOUT ARC â Government Partners Industry Partners Visit Us NEWS & EVENTS ▼ Events Calendar Annual Program Review Government/Industry Meeting On January 20th 2016, Dr. Anna Stefanopoulou, ARC Director and Professor of

  9. Talking with Mel Levine

    ERIC Educational Resources Information Center

    Prescott, Jennifer

    2005-01-01

    In his third book, "Ready or Not, Here Life Comes" (Simon & Shuster, 2005), pediatrician and brain researcher Dr. Mel Levine talks about the rising number of "start-up adults"--students who emerge from high school or college to find themselves woefully unprepared for the realities of a career. This article presents an interview with Dr. Levine…

  10. 10 CFR 55.5 - Communications.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Nuclear Regulatory Commission, Washington, DC 20555-0001. The guidance discusses, among other topics, the.... (b)(1) Except for test and research reactor facilities, the Director, Office of Nuclear Reactor... involving a test and research reactor facility licensed under 10 CFR part 50 and any related inquiry...

  11. 10 CFR 55.5 - Communications.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Nuclear Regulatory Commission, Washington, DC 20555-0001. The guidance discusses, among other topics, the.... (b)(1) Except for test and research reactor facilities, the Director, Office of Nuclear Reactor... involving a test and research reactor facility licensed under 10 CFR part 50 and any related inquiry...

  12. Second Opinion Reviews for Cancer Diagnoses in Anatomic Pathology: A Comprehensive Cancer Center's Experience.

    PubMed

    Strosberg, Carolina; Gibbs, Julie; Braswell, Diana; Leslie, Ronni R; Messina, Jane; Centeno, Barbara A; Coppola, Domenico

    2018-05-01

    The objective of this study was to define the rates of discrepancy between outside pathological diagnoses and secondary reviews. We assessed the rates of discordance between outside diagnoses and secondary reviews, categorizing by organ site and minor or major (affecting patient care) discordances. A total of 9,289 consecutive surgical pathology (SP) and cytopathology (CP) cases reviewed in 2015 were identified. For 8,191 outside SP cases reviewed, the overall discordance rate (DR) was 14.2% (2.2% major, 12.0% minor). Specifically, neuropathology had the highest DR (10.9%), cutaneous and breast the lowest (1.1% each). Among 1,098 CP cases, the total DR was 13.7% (3.0% major, 10.7% minor). The majority of CP cases (1,066) were non-gynecological and had a total DR of 13.4% (2.7% major, 10.7% minor). While major DR was low, certain subspecialties had high DRs. This project can help identify areas where focused education could help improve pathological diagnostic accuracy for cancer. Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  13. A Challenging Time in the History of Lamaze International: An Interview With Francine Nichols

    PubMed Central

    Zwelling, Elaine

    2006-01-01

    Dr. Francine Nichols—President of Lamaze International from 1988 to 1991 (when the organization was known as “the American Society for Psychoprophylaxis in Obstetrics” or “ASPO/Lamaze”) and the founding editor of The Journal of Perinatal Education in 1990—is a woman with many skills that have contributed to her success throughout her career. Dr. Nichols is a knowledgeable leader in maternal-newborn nursing, a respected nurse and childbirth educator, a researcher, and an author. However, these skills were not the abilities she relied upon the most to lead the Lamaze organization through a challenging period in the 1980s; rather, Dr. Nichols's tenacity, business savvy, and willingness to face controversy helped guide Lamaze International back on track so that it was able to grow into the strong organization it remains today. This interview took place by telephone on June 12, 2006, when Dr. Nichols was in Washington, D.C., for the summer to coordinate the National Institute of Nursing Research's Summer Genetics Institute, a doctoral-level course cosponsored by Georgetown University. PMID:17768430

  14. A challenging time in the history of lamaze international: an interview with francine nichols.

    PubMed

    Zwelling, Elaine

    2006-01-01

    Dr. Francine Nichols-President of Lamaze International from 1988 to 1991 (when the organization was known as "the American Society for Psychoprophylaxis in Obstetrics" or "ASPO/Lamaze") and the founding editor of The Journal of Perinatal Education in 1990-is a woman with many skills that have contributed to her success throughout her career. Dr. Nichols is a knowledgeable leader in maternal-newborn nursing, a respected nurse and childbirth educator, a researcher, and an author. However, these skills were not the abilities she relied upon the most to lead the Lamaze organization through a challenging period in the 1980s; rather, Dr. Nichols's tenacity, business savvy, and willingness to face controversy helped guide Lamaze International back on track so that it was able to grow into the strong organization it remains today. This interview took place by telephone on June 12, 2006, when Dr. Nichols was in Washington, D.C., for the summer to coordinate the National Institute of Nursing Research's Summer Genetics Institute, a doctoral-level course cosponsored by Georgetown University.

  15. Closeout Report: Experimental High Energy Physics Group at the University of South Alabama

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jenkins, Charles M; Godang, Romulus

    The High Energy Physics group at the University of South Alabama has been supported by this research grant (DE-FG02-96ER40970) since 1996. One researcher, Dr. Merrill Jenkins, has been supported on this grant during this time worked on fixed target experiments at the Fermi National Accelerator Laboratory, west of Chicago, Illinois. These experiments have been E-705, E-771, E-871 (HyperCP) and E-921 (CKM) before it was canceled for budgetary reasons. After the cancellation of CKM, Dr. Jenkins joined the Compact Muon Solenoid (CMS) experiment as an associate member via the High Energy Physics Group at the Florida State University. A second, recentlymore » tenured faculty member, Dr. Romulus Godang joined the group in 2009 and has been supported by this grant since then. Dr. Godang is working on the BaBaR experiment at SLAC and has joined the Belle-II experiment located in Japan at KEK. According to the instructions sent to us by our grant monitor, we are to concentrate on the activities over the last three years in this closeout report.« less

  16. IEA-R1 Nuclear Research Reactor: 58 Years of Operating Experience and Utilization for Research, Teaching and Radioisotopes Production

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cardenas, Jose Patricio Nahuel; Filho, Tufic Madi; Saxena, Rajendra

    IEA-R1 research reactor at the Instituto de Pesquisas Energeticas e Nucleares (Nuclear and Energy Research Institute) IPEN, Sao Paulo, Brazil is the largest power research reactor in Brazil, with a maximum power rating of 5 MWth. It is being used for basic and applied research in the nuclear and neutron related sciences, for the production of radioisotopes for medical and industrial applications, and for providing services of neutron activation analysis, real time neutron radiography, and neutron transmutation doping of silicon. IEA-R1 is a swimming pool reactor, with light water as the coolant and moderator, and graphite and beryllium as reflectors.more » The reactor was commissioned on September 16, 1957 and achieved its first criticality. It is currently operating at 4.5 MWth with a 60-hour cycle per week. In the early sixties, IPEN produced {sup 131}I, {sup 32}P, {sup 198}Au, {sup 24}Na, {sup 35}S, {sup 51}Cr and labeled compounds for medical use. During the past several years, a concerted effort has been made in order to upgrade the reactor power to 5 MWth through refurbishment and modernization programs. One of the reasons for this decision was to produce {sup 99}Mo at IPEN. The reactor cycle will be gradually increased to 120 hours per week continuous operation. It is anticipated that these programs will assure the safe and sustainable operation of the IEA-R1 reactor for several more years, to produce important primary radioisotopes {sup 99}Mo, {sup 125}I, {sup 131}I, {sup 153}Sm and {sup 192}Ir. Currently, all aspects of dealing with fuel element fabrication, fuel transportation, isotope processing, and spent fuel storage are handled by IPEN at the site. The reactor modernization program is slated for completion by 2015. This paper describes 58 years of operating experience and utilization of the IEA-R1 research reactor for research, teaching and radioisotopes production. (authors)« less

  17. Jim Starnes' Contributions to Residual Strength Analysis Methods for Metallic Structures

    NASA Technical Reports Server (NTRS)

    Young, Richard D.; Rose, Cheryl A.; Harris, Charles E.

    2005-01-01

    A summary of advances in residual strength analyses methods for metallic structures that were realized under the leadership of Dr. James H. Starnes, Jr., is presented. The majority of research led by Dr. Starnes in this area was conducted in the 1990's under the NASA Airframe Structural Integrity Program (NASIP). Dr. Starnes, respectfully referred to herein as Jim, had a passion for studying complex response phenomena and dedicated a significant amount of research effort toward advancing damage tolerance and residual strength analysis methods for metallic structures. Jim's efforts were focused on understanding damage propagation in built-up fuselage structure with widespread fatigue damage, with the goal of ensuring safety in the aging international commercial transport fleet. Jim's major contributions in this research area were in identifying the effects of combined internal pressure and mechanical loads, and geometric nonlinearity, on the response of built-up structures with damage. Analytical and experimental technical results are presented to demonstrate the breadth and rigor of the research conducted in this technical area. Technical results presented herein are drawn exclusively from papers where Jim was a co-author.

  18. Report to the Nuclear energy Research Advisory Committee (NERAC) Subcommittee on "Long-Term Isotope Research and Productions Plan" - Responses to Questions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ammoniums

    1999-07-01

    This report presents responses to two series of questions that were raised by a subcommittee of the Nuclear Energy Research Advisory Committee (NERAC) that has been charged with producing a ''Long-Term Isotope Research and Production Plan.'' The NERAC subcommittee is chaired by Dr. Richard Reba, and the Hanford Site Visit team, which comprises a subset of the subcommittee members, is chaired by Dr. Thomas Ruth. The first set of questions raised by the subcommittee on isotope production at the Hanford Site was received from Dr. Ruth on May 10, 1999, and the second set was received from him on Julymore » 5, 1999. Responses to the first set of questions were prepared as part of a June 1999 report entitled ''Isotope Production at the Hanford Site in Richland, Washington'' (PNNL 1999a). The responses to these questions are summarized in this document, with frequent references to the June 1999 report for additional details. Responses to the second set of questions from the NERAC subcommittee are presented in this document for the first time.« less

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stanislaus, Shirvel; Manweiler, Robert; Koetke, Donald

    This report summarizes the research carried out by the faculty, staff and students of Valparaiso University (VU) during the 30-year period from 1986 to 2015 using funds provided by the Medium Energy Nuclear Physics program of the Department of Energy (DOE). Three faculty members led the VU research group during the lifetime of the research grant. The three principal investigators responsible for the research were: Dr. Donald Koetke (1986 – 2007), Dr. Robert Manweiler (2008 – 2010), and Dr. Shirvel Stanislaus (2011 – 2015). During this period we participated and contributed to the progress of the following experiments: 1. Themore » MEGA Experiment at Los Alamos National Laboratory (LAMPF E969). 2. The Crystal Ball Experiment at Brookhaven National Laboratory (BNL/AGS E906, E913). 3. The NuSea Experiment at Fermilab (FNAL E866). 4. The TWIST Experiment at TRIUMF (TRIUMF E614). 5. The STAR Experiment at RHIC. 6. The nEDM Experiment at Oak Ridge National Laboratory. In the following sections we briefly describe the goals of the above experiments and the contributions made by the Valparaiso University personnel towards the progress of each project.« less

  20. Interview with Dr Ghassan K Abou-Alfa.

    PubMed

    Abou-Alfa, G K

    2016-11-01

    Ghassan K Abou-Alfa joined the Gastrointestinal Oncology Service at Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College in New York back in 2001. Dr Abou-Alfa specializes in the treatment of gastrointestinal malignancies. Dr Abou-Alfa received his medical degree from the American University of Beirut, Lebanon, and completed his post-doctoral training at Yale University School of Medicine. His research is dedicated to finding novel therapies and improving the effectiveness of the current therapies for hepatocellular carcinoma, cholangiocarcinoma and gallbladder cancer, while continuing to understand the basic mechanisms of the diseases and its therapy. Dr Abou-Alfa has invested several years in helping develop multi-tyrosine kinases and more immune-modulator therapies. Dr Abou-Alfa has many publications in the field. He led on many occasions international teams of investigators. Dr Abou-Alfa serves as the chair of the National Cancer Institute (NCI) Task Force for Hepatobiliary Cancers and the chair of the AIDS Malignancy Consortium (AMC) Non-AIDS Defining Malignancies (NADC) Liver/GI Task Force. Dr Abou-Alfa also co-chairs the hepatobiliary cancers subgroup of the Alliance cooperative group, and is a cadre member of both the gastrointestinal cancers and pharmacogenomics and population pharmacology committees. Dr Abou-Alfa who has lectured worldwide on the subject on gastrointestinal malignancies, is also a strong advocate for raising awareness and support for improving the outcome of patients with this disease, and enhancing oncologic education worldwide.

  1. Final Scientific/Technical Report, DE-FG02-06ER64171, Integrated Nucleic Acid System for In-Field Monitoring of Microbial Community Dynamics and Metabolic Activity – Subproject to Co-PI Eric E. Roden

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eric E. Roden

    2009-07-08

    This report summarizes research conducted in conjunction with a project entitled “Integrated Nucleic Acid System for In-Field Monitoring of Microbial Community Dynamics and Metabolic Activity”, which was funded through the Integrative Studies Element of the former NABIR Program (now the Environmental Remediation Sciences Program) within the Office of Biological and Environmental Research. Dr. Darrell Chandler (originally at Argonne National Laboratory, now with Akonni Biosystems) was the overall PI/PD for the project. The overall project goals were to (1) apply a model iron-reducer and sulfate-reducer microarray and instrumentation systems to sediment and groundwater samples from the Scheibe et al. FRC Areamore » 2 field site, UMTRA sediments, and other DOE contaminated sites; (2) continue development and expansion of a 16S rRNA/rDNA¬-targeted probe suite for microbial community dynamics as new sequences are obtained from DOE-relevant sites; and (3) address the fundamental molecular biology and analytical chemistry associated with the extraction, purification and analysis of functional genes and mRNA in environmental samples. Work on the UW subproject focused on conducting detailed batch and semicontinuous culture reactor experiments with uranium-contaminated FRC Area 2 sediment. The reactor experiments were designed to provide coherent geochemical and microbiological data in support of microarray analyses of microbial communities in Area 2 sediments undergoing biostimulation with ethanol. A total of four major experiments were conducted (one batch and three semicontinuous culture), three of which (the batch and two semicontinuous culture) provided samples for DNA microarray analysis. A variety of other molecular analyses (clone libraries, 16S PhyloChip, RT-PCR, and T-RFLP) were conducted on parallel samples from the various experiments in order to provide independent information on microbial community response to biostimulation.« less

  2. Evaluation of nuclear-facility decommissioning projects. Summary report: Ames Laboratory Research Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Link, B.W.; Miller, R.L.

    1983-07-01

    This document summarizes the available information concerning the decommissioning of the Ames Laboratory Research Reactor (ALRR), a five-megawatt heavy water moderated and cooled research reactor. The data were placed in a computerized information retrieval/manipulation system which permits its future utilization for purposes of comparative analysis. This information is presented both in detail in its computer output form and also as a manually assembled summarization which highlights the more important aspects of the decommissioning program. Some comparative information with reference to generic decommissioning data extracted from NUREG/CR 1756, Technology, Safety and Costs of Decommissioning Nuclear Research and Test Reactors, is included.

  3. Quantity and management of spent fuel from prototype and research reactors in Germany

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dorr, Sabine; Bollingerfehr, Wilhelm; Filbert, Wolfgang

    Within the scope of an R and D project (project identification number FKZ 02 S 8679) sponsored by BMBF (Federal Ministry of Education and Research), the current state of storage and management of fuel elements from prototype and research reactors was established, and an approach for their future storage/management was developed. The spent fuels from prototype and research reactors in Germany that require disposal were specified and were described in regard to their repository-relevant characteristics. As there are currently no casks licensed for disposal in Germany, descriptions of casks that were considered to be suitable were provided. Based on themore » information provided on the spent fuel from prototype and research reactors and the potential casks, a technical disposal concept was developed. In this context, concepts to integrate the spent fuel from prototype and research reactors into existing disposal concepts for spent fuel from German nuclear power plants and for waste from reprocessing were developed for salt and clay formations. (authors)« less

  4. Assessment of Nuclear Fuels using Radiographic Thickness Measurement Method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Muhammad Abir; Fahima Islam; Hyoung Koo Lee

    2014-11-01

    The Convert branch of the National Nuclear Security Administration (NNSA) Global Threat Reduction Initiative (GTRI) focuses on the development of high uranium density fuels for research and test reactors for nonproliferation. This fuel is aimed to convert low density high enriched uranium (HEU) based fuel to high density low enriched uranium (LEU) based fuel for high performance research reactors (HPRR). There are five U.S. reactors that fall under the HPRR category, including: the Massachusetts Institute of Technology Reactor (MITR), the National Bureau of Standards Reactor (NBSR), the Missouri University Research Reactor (UMRR), the Advanced Test Reactor (ATR), and the Highmore » Flux Isotope Reactor (HFIR). U-Mo alloy fuel phase in the form of either monolithic or dispersion foil type fuels, such as ATR Full-size In center flux trap Position (AFIP) and Reduced Enrichment for Research and Test Reactor (RERTR), are being designed for this purpose. The fabrication process1 of RERTR is susceptible to introducing a variety of fuel defects. A dependable quality control method is required during fabrication of RERTR miniplates to maintain the allowable design tolerances, therefore evaluating and analytically verifying the fabricated miniplates for maintaining quality standards as well as safety. The purpose of this work is to analyze the thickness of the fabricated RERTR-12 miniplates using non-destructive technique to meet the fuel plate specification for RERTR fuel to be used in the ATR.« less

  5. Current and anticipated uses of thermal hydraulic codes at the Japan Atomic Energy Research Institute

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Akimoto, Hajime; Kukita; Ohnuki, Akira

    1997-07-01

    The Japan Atomic Energy Research Institute (JAERI) is conducting several research programs related to thermal-hydraulic and neutronic behavior of light water reactors (LWRs). These include LWR safety research projects, which are conducted in accordance with the Nuclear Safety Commission`s research plan, and reactor engineering projects for the development of innovative reactor designs or core/fuel designs. Thermal-hydraulic and neutronic codes are used for various purposes including experimental analysis, nuclear power plant (NPP) safety analysis, and design assessment.

  6. 10 CFR 55.5 - Communications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... Nuclear Regulatory Commission, Washington, DC 20555-0001. The guidance discusses, among other topics, the.... (b)(1) Except for test and research reactor facilities, the Director, Office of Nuclear Reactor... this part involving a test and research reactor facility licensed under 10 CFR part 50 and any related...

  7. The present situations and perspectives on utilization of research reactors in Thailand

    NASA Astrophysics Data System (ADS)

    Chongkum, Somporn

    2002-01-01

    The Thai Research Reactor 1/Modification 1, a TRIGA Mark III reactor, went critical on November 7, 1977. It has been playing a central role in the development of both Office of Atomic Energy for Peace (OAEP) and nuclear application in Thailand. It has a maximum power of 2 MW (thermal) at steady state and a pulsing capacity of 2000 MW. The highest thermal neutron flux at a central thimber is 1×10 13 n/cm 2/s, which is extensively utilized for radioisotope production, neutron activation analysis and neutron beam experiments, i.e. neutron scattering, prompt gamma analysis and neutron radiography. Following the nuclear technological development, the OAEP is in the process of establishing the Ongkharak Nuclear Research Center (ONRC). The center is being built in Nakhon Nayok province, 60 km northeast of Bangkok. The centerpiece of the ONRC is a multipurpose 10 MW TRIGA research reactor. Facilities are included for the production of radioisotopes for medicine, industry and agriculture, neutron transmutation doping of silicon, and neutron capture therapy. The neutron beam facilities will also be utilized for applied research and technology development as well as training in reactor operations, performance of experiments and reactor physics. This paper describes a recent program of utilization as well as a new research reactor for enlarging the perspectives of its utilization in the future.

  8. Importance of holographic light in the emerging field of mind-body healing

    NASA Astrophysics Data System (ADS)

    Booth, Roberta

    2000-10-01

    Healing with color has been researched and documented worldwide for centuries. Every single part of the brain and every cell in the body is effected by light. Chinese and Russian scientists demonstrated that the acupuncture meridians transmit light. Dr. Peter Mandel, German chiropractic physician and acupuncturist, states that the acupuncture points are especially sensitive to electromagnetic waves within the spectrum of visible light and microwave energy, and all cells constantly emit and absorb small pockets of electromagnetic radiation or light, called biophotons. The harmony or disharmony of cells has been documented. Kirlian photography, to photography the aura was invented by Russians Semyon and Valentina Kirlian. Photo therapy and light research are being practiced worldwide. In the United States, Dr. Jacob Lieberman has written an influential book Light Medicine of the Future. In 1992 the first Light Years Ahead conference was held. (#5 1996) Dr. Brian Breiling and Dr. Lee Hartley brought together experts in the field to discuss the many potentials of light therapy. My present research in this area has focused on narrow band frequencies through the use of holography. Its therapeutic applications of color healing in this research are both critical and fundamental. My current work, The Chakras, seven reflection holograms on silver halide, relate to the wheels of light described in the earliest recorded Indian history. I will discus the chakras, this ancient metaphysical system under the new light of popular western metaphors and visionary art, how the chakras relate to the seven colors of the rainbow, the electromagnetic waves, and the connection to color holography in healing light therapy. I will be citing concurrent research in color healing, and the important areas of research that are necessary to have significant impact on future directions. Holography in the future will constitute a major frontier in discovery.

  9. Low-power lead-cooled fast reactor loaded with MOX-fuel

    NASA Astrophysics Data System (ADS)

    Sitdikov, E. R.; Terekhova, A. M.

    2017-01-01

    Fast reactor for the purpose of implementation of research, education of undergraduate and doctoral students in handling innovative fast reactors and training specialists for atomic research centers and nuclear power plants (BRUTs) was considered. Hard neutron spectrum achieved in the fast reactor with compact core and lead coolant. Possibility of prompt neutron runaway of the reactor is excluded due to the low reactivity margin which is less than the effective fraction of delayed neutrons. The possibility of using MOX fuel in the BRUTs reactor was examined. The effect of Keff growth connected with replacement of natural lead coolant to 208Pb coolant was evaluated. The calculations and reactor core model were performed using the Serpent Monte Carlo code.

  10. Human radiation studies: Remembering the early years: Oral history of physician James S. Robertson, M.D., Ph.D., conducted January 20, 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-09-01

    This report is a transcript of in interview of Dr. James S. Robertson by representatives of the DOE Office of Human Radiation Experiments. Dr. Robertson was chosen for this interview because of his research at Brookhaven National Laboratory, especially on Boron Neutron Capture Therapy (BNCT); his work at the United States Naval Defense Laboratory; and his work at the Atomic Energy Commission. After a brief biographical sketch Dr. Robertson discusses research on human subjects at Berkeley, his contributions to the beginnings of Neutron Capture Therapy at Brookhaven, his participation with the Brookhaven Human Use Committee, his involvement in the studymore » of the effects of Castle Bravo event on the Marshallese, and his work with the Naval Radiological Defense Laboratory.« less

  11. Assessment of Diabetic Retinopathy Using Nonmydriatic Ultra-Widefield Scanning Laser Ophthalmoscopy (Optomap) Compared With ETDRS 7-Field Stereo Photography

    PubMed Central

    Kernt, Marcus; Hadi, Indrawati; Pinter, Florian; Seidensticker, Florian; Hirneiss, Christoph; Haritoglou, Christos; Kampik, Anselm; Ulbig, Michael W.; Neubauer, Aljoscha S.

    2012-01-01

    OBJECTIVE To compare the diagnostic properties of a nonmydriatic 200° ultra-widefield scanning laser ophthalmoscope (SLO) versus mydriatic Early Treatment of Diabetic Retinopathy Study (ETDRS) 7-field photography for diabetic retinopathy (DR) screening. RESEARCH DESIGN AND METHODS A consecutive series of 212 eyes of 141 patients with different levels of DR were examined. Grading of DR and clinically significant macular edema (CSME) from mydriatic ETDRS 7-field stereo photography was compared with grading obtained by Optomap Panoramic 200 SLO images. All SLO scans were performed through an undilated pupil, and no additional clinical information was used for evaluation of all images by the two independent, masked, expert graders. RESULTS Twenty-two eyes from ETDRS 7-field photography and 12 eyes from Optomap were not gradable by at least one grader because of poor image quality. A total of 144 eyes were analyzed regarding DR level and 155 eyes regarding CSME. For ETDRS 7-field photography, 22 eyes (18 for grader 2) had no or mild DR (ETDRS levels ≤ 20) and 117 eyes (111 for grader 2) had no CSME. A highly substantial agreement between both Optomap DR and CSME grading and ETDRS 7-field photography existed with κ = 0.79 for DR and 0.73 for CSME for grader 1, and κ = 0.77 (DR) and 0.77 (CSME) for grader 2. CONCLUSIONS Determination of CSME and grading of DR level from Optomap Panoramic 200 nonmydriatic images show a positive correlation with mydriatic ETDRS 7-field stereo photography. Both techniques are of sufficient quality to assess DR and CSME. Optomap Panoramic 200 images cover a larger retinal area and therefore may offer additional diagnostic properties. PMID:22912430

  12. PREFACE: Plasma Physics by Laser and Applications 2013 Conference (PPLA2013)

    NASA Astrophysics Data System (ADS)

    Nassisi, V.; Giulietti, D.; Torrisi, L.; Delle Side, D.

    2014-04-01

    The ''Plasma Physics by Laser and Applications'' Conference (PPLA 2013) is a biennial meeting in which the National teams involved in Laser-Plasma Interaction at high intensities communicate their late results comparing with the colleagues from the most important European Laser Facilities. The sixth appointment has been organized in Lecce, Italy, from 2 to 4 October 2013 at the Rector Palace of the University of Salento. Surprising results obtained by laser-matter interaction at high intensities, as well as, non-equilibrium plasma generation, laser-plasma acceleration and related secondary sources, diagnostic methodologies and applications based on lasers and plasma pulses have transferred to researchers the enthusiasm to perform experiments ad maiora. The plasma generated by powerful laser pulses produces high kinetic particles and energetic photons that may be employed in different fields, from medicine to microelectronics, from engineering to nuclear fusion, from chemistry to environment. A relevant interest concerns the understanding of the fundamental physical phenomena, the employed lasers, plasma diagnostics and their consequent applications. For this reason we need continuous updates, meetings and expertise exchanges in this field in order to follow the evolution and disclose information, that has been done this year in Lecce, discussing and comparing the experiences gained in various international laboratories. The conference duration, although limited to just 3 days, permitted to highlight important aspects of the research in the aforementioned fields, giving discussion opportunities about the activities of researchers of high international prestige. The program consisted of 10 invited talks, 17 oral talks and 17 poster contributions for a total of 44 communications. The presented themes covered different areas and, far from being exhaustive gave updates, stimulating useful scientific discussions. The Organizers belong to three Italian Universities, Professor V Nassisi of Salento University, Professor D Giulietti of Pisa University and Professor L Torrisi of Messina University. The Scientific Committee was constituted by colleagues coming from different European laboratories: Dr F Belloni from European Commission, Bruxell, Belgium; Professor M Borghesi from the Queens University of Belfast, United Kingdom; Professor L Calcagno from Catania University, Italy; Professor D Giulietti from Pisa University, Italy; Dr J Krása from Academy of Science of Czech Republic, Prague; Professor V Malka from Laboratoire d'Optique Appliquée, Palaiseau, France; Professor V Nassisi from Salento University, Italy; Professor L Palladino from L'Aquila University, Italy; Professor L Torrisi from Messina University, Italy; Professor Ullschmied from Academy of Science of Czech Republic, Prague; Professor J Wolowski from Institute of Plasma Physics and Laser Microfusion of Warsaw, Poland and Dr J. Badziak from Institute of Plasma Physics and Laser Microfusion of Warsaw, Poland. The Local Organizing team was composed by: Dr G Buccolieri, Dr D Delle Side, Dr F Paladini and Dr L Velardi from Salento University and Dr M Cutroneo from Messina University. The Scientific secretariat was coordinated by Dr D. Dell'Anna from Salento University. The Topics discussed in the conference were: ·Laser-Matter interactions; ·Laser ion sources; ·Electron beam generation; ·Physics of non-equilibrium plasmas; ·Theoretical models in plasmas; ·Photons and particles emission from pulsed plasmas; ·Ion acceleration from plasma; ·Fs laser pulses; ·Pulsed laser deposition; ·Applications of laser beams and pulsed plasmas; ·Techniques of characterization of plasmas. The colleagues attending the conference were about 80. The Chairmen and Presidents of the different Conference sessions were: Professor V Nassisi, Professor D Giulietti, Professor L Torrisi, Professor M Borghesi, Dr K Rohlena (ASCR of Prague, Czech Republic), Professor D Neely (RAL, Oxon, UK), Dr J Ullschmied (ASCR, Prague, Czech Republic), Professor S Ratynskaia (Royal Institute of Technology, Stockholm, Sweden), Dr J. Krása, Dr J. Badziak. The award Leos Laska, a Czech colleague which gave in its country relevant contributions to development of the experimental activities in these research fields, has been proposed in memory to his work and to stimulate the interest of young researchers in this important sector. The Scientific Committee conferred the prize to Dr Mariapompea Cutroneo, PhD in Physics of Messina University, for her activity in the field of new methodologies related to the ion acceleration in laser-generated plasma. The widespread success of the event suggests we will meet again, next 2015, in another South Italy venue, as wonderful and welcoming as Lecce was. Vincenzo Nassisi, Danilo Giulietti, Lorenzo Torrisi and Domenico Delle Side

  13. Irradiation Tests Supporting LEU Conversion of Very High Power Research Reactors in the US

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woolstenhulme, N. E.; Cole, J. I.; Glagolenko, I.

    The US fuel development team is developing a high density uranium-molybdenum alloy monolithic fuel to enable conversion of five high-power research reactors. Previous irradiation tests have demonstrated promising behavior for this fuel design. A series of future irradiation tests will enable selection of final fuel fabrication process and provide data to qualify the fuel at moderately-high power conditions for use in three of these five reactors. The remaining two reactors, namely the Advanced Test Reactor and High Flux Isotope Reactor, require additional irradiation tests to develop and demonstrate the fuel’s performance with even higher power conditions, complex design features, andmore » other unique conditions. This paper reviews the program’s current irradiation testing plans for these moderately-high irradiation conditions and presents conceptual testing strategies to illustrate how subsequent irradiation tests will build upon this initial data package to enable conversion of these two very-high power research reactors.« less

  14. 10 CFR 171.3 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... holding an operating license for a power reactor, test reactor or research reactor issued under part 50 of... authorizes operation of a power reactor. The regulations in this part also apply to any person holding a...

  15. KSC-04PD-1998

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. (From left) Dr. Julian Earls, director of NASA Glenn Research Center, astronaut Leland Melvin, Sara Thompson, team lead, and KSC Deputy Director Dr. Woodrow Whitlow Jr. pose for a photo at Ronald E. McNair High School in Atlanta, a NASA Explorer School, after a presentation. Dr. Whitlow visited the school to share The vision for space exploration with the next generation of explorers. Whitlow talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space. Dr. Earls discussed the future and the vision for space, plus the NASA careers needed to meet the vision. Melvin talked about the importance of teamwork and what it takes for mission success.

  16. KSC-04PD-1994

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. From left, Sarah Copelin-Wood, chair of the Board of Education, astronaut Leland Melvin, Dr. Julian Earls, Dr. Woodrow Whitlow Jr. and a school board member pose for photos after a presentation to students at Ronald E. McNair High School in Atlanta, a NASA Explorer School. Dr. Earls is director of NASA Glenn Research Center. During their visit to the school, Whitlow talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space. Dr. Earls discussed the future and the vision for space, plus the NASA careers needed to meet the vision. Melvin talked about the importance of teamwork and what it takes for mission success.

  17. Mitochondrial Disease Sequence Data Resource (MSeqDR): a global grass-roots consortium to facilitate deposition, curation, annotation, and integrated analysis of genomic data for the mitochondrial disease clinical and research communities.

    PubMed

    Falk, Marni J; Shen, Lishuang; Gonzalez, Michael; Leipzig, Jeremy; Lott, Marie T; Stassen, Alphons P M; Diroma, Maria Angela; Navarro-Gomez, Daniel; Yeske, Philip; Bai, Renkui; Boles, Richard G; Brilhante, Virginia; Ralph, David; DaRe, Jeana T; Shelton, Robert; Terry, Sharon F; Zhang, Zhe; Copeland, William C; van Oven, Mannis; Prokisch, Holger; Wallace, Douglas C; Attimonelli, Marcella; Krotoski, Danuta; Zuchner, Stephan; Gai, Xiaowu

    2015-03-01

    Success rates for genomic analyses of highly heterogeneous disorders can be greatly improved if a large cohort of patient data is assembled to enhance collective capabilities for accurate sequence variant annotation, analysis, and interpretation. Indeed, molecular diagnostics requires the establishment of robust data resources to enable data sharing that informs accurate understanding of genes, variants, and phenotypes. The "Mitochondrial Disease Sequence Data Resource (MSeqDR) Consortium" is a grass-roots effort facilitated by the United Mitochondrial Disease Foundation to identify and prioritize specific genomic data analysis needs of the global mitochondrial disease clinical and research community. A central Web portal (https://mseqdr.org) facilitates the coherent compilation, organization, annotation, and analysis of sequence data from both nuclear and mitochondrial genomes of individuals and families with suspected mitochondrial disease. This Web portal provides users with a flexible and expandable suite of resources to enable variant-, gene-, and exome-level sequence analysis in a secure, Web-based, and user-friendly fashion. Users can also elect to share data with other MSeqDR Consortium members, or even the general public, either by custom annotation tracks or through the use of a convenient distributed annotation system (DAS) mechanism. A range of data visualization and analysis tools are provided to facilitate user interrogation and understanding of genomic, and ultimately phenotypic, data of relevance to mitochondrial biology and disease. Currently available tools for nuclear and mitochondrial gene analyses include an MSeqDR GBrowse instance that hosts optimized mitochondrial disease and mitochondrial DNA (mtDNA) specific annotation tracks, as well as an MSeqDR locus-specific database (LSDB) that curates variant data on more than 1300 genes that have been implicated in mitochondrial disease and/or encode mitochondria-localized proteins. MSeqDR is integrated with a diverse array of mtDNA data analysis tools that are both freestanding and incorporated into an online exome-level dataset curation and analysis resource (GEM.app) that is being optimized to support needs of the MSeqDR community. In addition, MSeqDR supports mitochondrial disease phenotyping and ontology tools, and provides variant pathogenicity assessment features that enable community review, feedback, and integration with the public ClinVar variant annotation resource. A centralized Web-based informed consent process is being developed, with implementation of a Global Unique Identifier (GUID) system to integrate data deposited on a given individual from different sources. Community-based data deposition into MSeqDR has already begun. Future efforts will enhance capabilities to incorporate phenotypic data that enhance genomic data analyses. MSeqDR will fill the existing void in bioinformatics tools and centralized knowledge that are necessary to enable efficient nuclear and mtDNA genomic data interpretation by a range of shareholders across both clinical diagnostic and research settings. Ultimately, MSeqDR is focused on empowering the global mitochondrial disease community to better define and explore mitochondrial diseases. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Mitochondrial Disease Sequence Data Resource (MSeqDR): A global grass-roots consortium to facilitate deposition, curation, annotation, and integrated analysis of genomic data for the mitochondrial disease clinical and research communities

    PubMed Central

    Falk, Marni J.; Shen, Lishuang; Gonzalez, Michael; Leipzig, Jeremy; Lott, Marie T.; Stassen, Alphons P.M.; Diroma, Maria Angela; Navarro-Gomez, Daniel; Yeske, Philip; Bai, Renkui; Boles, Richard G.; Brilhante, Virginia; Ralph, David; DaRe, Jeana T.; Shelton, Robert; Terry, Sharon; Zhang, Zhe; Copeland, William C.; van Oven, Mannis; Prokisch, Holger; Wallace, Douglas C.; Attimonelli, Marcella; Krotoski, Danuta; Zuchner, Stephan; Gai, Xiaowu

    2014-01-01

    Success rates for genomic analyses of highly heterogeneous disorders can be greatly improved if a large cohort of patient data is assembled to enhance collective capabilities for accurate sequence variant annotation, analysis, and interpretation. Indeed, molecular diagnostics requires the establishment of robust data resources to enable data sharing that informs accurate understanding of genes, variants, and phenotypes. The “Mitochondrial Disease Sequence Data Resource (MSeqDR) Consortium” is a grass-roots effort facilitated by the United Mitochondrial Disease Foundation to identify and prioritize specific genomic data analysis needs of the global mitochondrial disease clinical and research community. A central Web portal (https://mseqdr.org) facilitates the coherent compilation, organization, annotation, and analysis of sequence data from both nuclear and mitochondrial genomes of individuals and families with suspected mitochondrial disease. This Web portal provides users with a flexible and expandable suite of resources to enable variant-, gene-, and exome-level sequence analysis in a secure, Web-based, and user-friendly fashion. Users can also elect to share data with other MSeqDR Consortium members, or even the general public, either by custom annotation tracks or through use of a convenient distributed annotation system (DAS) mechanism. A range of data visualization and analysis tools are provided to facilitate user interrogation and understanding of genomic, and ultimately phenotypic, data of relevance to mitochondrial biology and disease. Currently available tools for nuclear and mitochondrial gene analyses include an MSeqDR GBrowse instance that hosts optimized mitochondrial disease and mitochondrial DNA (mtDNA) specific annotation tracks, as well as an MSeqDR locus-specific database (LSDB) that curates variant data on more than 1,300 genes that have been implicated in mitochondrial disease and/or encode mitochondria-localized proteins. MSeqDR is integrated with a diverse array of mtDNA data analysis tools that are both freestanding and incorporated into an online exome-level dataset curation and analysis resource (GEM.app) that is being optimized to support needs of the MSeqDR community. In addition, MSeqDR supports mitochondrial disease phenotyping and ontology tools, and provides variant pathogenicity assessment features that enable community review, feedback, and integration with the public ClinVar variant annotation resource. A centralized Web-based informed consent process is being developed, with implementation of a Global Unique Identifier (GUID) system to integrate data deposited on a given individual from different sources. Community-based data deposition into MSeqDR has already begun. Future efforts will enhance capabilities to incorporate phenotypic data that enhance genomic data analyses. MSeqDR will fill the existing void in bioinformatics tools and centralized knowledge that are necessary to enable efficient nuclear and mtDNA genomic data interpretation by a range of shareholders across both clinical diagnostic and research settings. Ultimately, MSeqDR is focused on empowering the global mitochondrial disease community to better define and explore mitochondrial disease. PMID:25542617

  19. 78 FR 29121 - Strategic Environmental Research and Development Program, Scientific Advisory Board; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... Director. 9:25 a.m Resource Dr. John Hall, Conservation and Resource Climate Change Conservation and Overview. Climate Change, Program Manager. 9:35 a.m 13 RC01-001 (RC- Dr. Curt Storlazzi, 2334): The Impact U.S. Geological of Sea-Level Rise Survey, Santa and Climate Change Cruz, CA. on Department of...

  20. It Really Is All about the Child: An Interview with Dr. Edward Hallowell

    ERIC Educational Resources Information Center

    Peters, Dane L.

    2012-01-01

    In a decade when brain research has helped people understand learning difficulties in children, and people have seen increased media attention on the use of medications to treat attention deficit/hyperactivity disorder (ADHD) in children and adults, Dr. Edward (Ned) Hallowell has worked tirelessly to educate the medical profession, parents,…

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