Sample records for draft integrated science

  1. 76 FR 65722 - Notification of Two Public Teleconferences; Clean Air Scientific Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-24

    ... EPA's Integrated Science Assessment for Lead (First External Review Draft, May 2011) and EPA's draft... Science Assessment for Lead (First External Review Draft, May 2011) should be directed to Dr. Ellen... Integrated Science Assessment for Lead (First External Review Draft, May 2011) and EPA's draft Near-Road NO 2...

  2. 76 FR 26284 - Draft Integrated Science Assessment for Lead (Pb)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9302-5; Docket ID No. EPA-HQ-ORD-2011-0051] Draft Integrated... the availability of a document titled, ``First External Review Draft Integrated Science Assessment for Lead'' (EPA/600/R-10/075A). This draft document was prepared by the National Center for Environmental...

  3. 76 FR 60820 - Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... Science Assessment for Ozone and Related Photochemical Oxidants AGENCY: Environmental Protection Agency... Review Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants'' (EPA/600/R-10... standards (NAAQS) for ozone. EPA is releasing this draft document to seek review by the Clean Air Scientific...

  4. Integrated Science Assessment (ISA) for Lead (First External Review Draft, May 2011)

    EPA Science Inventory

    EPA announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) was made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science and will ...

  5. Integrated Science Assessment (ISA) for Lead (Second External Review Draft, Mar 2012)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) has been made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science...

  6. Integrated Science Assessment (ISA) for Lead (Third External Review Draft, Nov 2012)

    EPA Science Inventory

    EPA announced that the Third External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) was made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science and will ...

  7. Integrated Science Assessment (ISA) of Ozone and Related Photochemical Oxidants (Second External Review Draft, Sep 2011)

    EPA Science Inventory

    EPA has released the Integrated Science Assessment of Ozone and Related Photochemical Oxidants (Second External Review Draft) for independent peer review and public review. This draft document represents a concise synthesis and evaluation of the most policy-relevant scienc...

  8. Integrated Science Assessment (ISA) of Ozone and Related Photochemical Oxidants (Third External Review Draft, Jun 2012)

    EPA Science Inventory

    EPA has released the Integrated Science Assessment of Ozone and Related Photochemical Oxidants (Third External Review Draft) for independent peer review and public review. This draft document represents a concise synthesis and evaluation of the most policy-relevant science...

  9. 76 FR 51365 - Notification of a Public Teleconference of the Clean Air Scientific Advisory Committee (CASAC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... Assessment for Lead (First External Review Draft--May 2011). DATES: The CASAC Lead Review Panel... Integrated Science Assessment for Lead (First External Review Draft--May 2011) and to provide consultative... draft letter reviewing EPA's Integrated Science Assessment for Lead (First External Review Draft--May...

  10. Integrated Science Assessment (ISA) for Carbon Monoxide (Second External Review Draft, Sep 2009)

    EPA Science Inventory

    EPA announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes was made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of t...

  11. Integrated Science Assessment (ISA) for Carbon Monoxide (First External Review Draft, Mar 2009)

    EPA Science Inventory

    EPA announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes was made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of th...

  12. Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria (Second External Review Draft, 2008)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation...

  13. Integrated Science Assessment (ISA) for Particulate Matter (First External Review Draft, Dec 2008)

    EPA Science Inventory

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Particulate Matter and related Annexes have been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and e...

  14. 76 FR 76725 - Notification of a Public Meeting of the Clean Air Scientific Advisory Committee (CASAC); Ozone...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-08

    ... and Related Photochemical Oxidants (Second External Review Draft--September 2011). DATES: The CASAC... second external review draft of the Integrated Science Assessment for Ozone and Related Photochemical... reviewed EPA's first external review draft of the Integrated Science Assessment for Ozone and Related...

  15. Integrated Science Assessment (ISA) of Ozone and Related Photochemical Oxidants (First External Review Draft, Feb 2011)

    EPA Science Inventory

    EPA announced that the First External Review Draft of the Integrated Science Assessment for Ozone and Related Photochemical Oxidants has been made available for independent peer review and public review. This draft document represents a concise synthesis and evaluation of ...

  16. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (External Review Draft, Nov 2015)

    EPA Science Inventory

    EPA announced the availability of the external review draft of the Integrated Science Assessment for Sulfur Oxides– Health Criteria for public comment and independent peer review in a November 24, 2015 Federal Register Notice. This draft document provides EPA’s evaluati...

  17. 75 FR 69078 - Workshop To Review Draft Materials for the Lead (Pb) Integrated Science Assessment (ISA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9224-7] Workshop To Review Draft Materials for the Lead (Pb) Integrated Science Assessment (ISA) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of Workshop... (NAAQS) for Lead (Pb), EPA is announcing that a workshop to evaluate initial draft materials for the Pb...

  18. Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria (First External Review Draft, 2007)

    EPA Science Inventory

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and eva...

  19. Integrated Science Assessment (ISA) for Oxides of Nitrogen and Sulfur - Environmental Criteria (Second External Review Draft, Aug 2008)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Oxides of Nitrogen and Sulfur - Environmental Criteria has been made available for independent peer review and public review. This draft ISA document represents a conci...

  20. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (First External Review Draft, Sep 2007)

    EPA Science Inventory

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluatio...

  1. Integrated Science Assessment (ISA) for Oxides of Nitrogen and Sulfur - Environmental Criteria (First External Review Draft, Dec 2007)

    EPA Science Inventory

    EPA is announcing that the First External Review Draft of the Integrated Science Assessment (ISA) for Oxides of Nitrogen and Sulfur – Environmental Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise ...

  2. Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria (First External Review Draft, 2013)

    EPA Science Inventory

    EPA is announcing the availability of the First External Review Draft of the Integrated Science Assessment for Oxides of Nitrogen – Health Criteria for public comment and independent peer review. This draft document provides EPA’s evaluation and synthesis of the most polic...

  3. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (Second External Review Draft, May 2008)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluati...

  4. 76 FR 72919 - Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... Science Assessment for Ozone and Related Photochemical Oxidants AGENCY: Environmental Protection Agency... Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants'' (EPA/600/R-10/076B... national ambient air quality standards (NAAQS) for ozone. DATES: The public comment period began on...

  5. 76 FR 17121 - Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-28

    ... Science Assessment for Ozone and Related Photochemical Oxidants AGENCY: Environmental Protection Agency... Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants'' (EPA/600/R-10/076A... ambient air quality standards (NAAQS) for ozone. DATES: The public comment period began on February 28...

  6. Integrated Science Assessment (ISA) for Oxides of Nitrogen, Oxides of Sulfur and Particulate Matter Ecological Criteria (Second External Review Draft)

    EPA Science Inventory

    This draft Integrated Science Assessment (ISA) represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision on retaining or revising the current secondary standards for NO2, SO

  7. NOAA draft scientific integrity policy: Comment period open through 20 August

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-08-01

    The National Oceanic and Atmospheric Administration (NOAA) is aiming to finalize its draft scientific integrity policy possibly by the end of the year, Larry Robinson, NOAA assistant secretary for conservation and management, indicated during a 28 July teleconference. The policy “is key to fostering an environment where science is encouraged, nurtured, respected, rewarded, and protected,” Robinson said, adding that the agency's comment period for the draft policy, which was released on 16 June, ends on 20 August. “Science underpins all that NOAA does. This policy is one piece of a broader effort to strengthen NOAA science,” Robinson said, noting that the draft “represents the first ever scientific integrity policy for NOAA. Previously, our policy only addressed research misconduct and focused on external grants. What's new about this policy is that it establishes NOAA's principles for scientific integrity, a scientific code of conduct, and a code of ethics for science supervision and management.”

  8. 78 FR 27374 - Workshop To Review Initial Draft Materials for the Nitrogen Oxides (NOX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... materials that will inform the development of the NO X Integrated Science Assessment (ISA) for health... ENVIRONMENTAL PROTECTION AGENCY [FRL-9812-6] Workshop To Review Initial Draft Materials for the Nitrogen Oxides (NO X ) Integrated Science Assessment (ISA) for Health Effects AGENCY: Environmental...

  9. Draft Plan for Development of the Integrated Science Assessment for Nitrogen Oxides - Health Criteria

    EPA Science Inventory

    EPA has announced a draft development plan for the next Integrated Science Assessment (ISA) for the health effects of nitrogen oxides (NOX) which will serve as the scientific basis for review of the primary (health-based) National Ambient Air Quality Standard for nitrogen dioxide...

  10. Integrated Science Assessment (ISA) for Particulate Matter (Second External Review Draft, Jul 2009)

    EPA Science Inventory

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Particulate Matter (PM) have been made available for independent peer review and public review. The ISA reflects the latest scientific knowledge useful in indicating the kind...

  11. EPA scientific integrity policy draft

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-08-01

    The U.S. Environmental Protection Agency (EPA) issued its draft scientific integrity policy on 5 August. The draft policy addresses scientific ethical standards, communications with the public, the use of advisory committees and peer review, and professional development. The draft policy was developed by an ad hoc group of EPA senior staff and scientists in response to a December 2010 memorandum on scientific integrity from the White House Office of Science and Technology Policy. The agency is accepting public comments on the draft through 6 September; comments should be sent to osa.staff@epa.gov. For more information, see http://www.epa.gov/stpc/pdfs/draft-scientific-integrity-policy-aug2011.pdf.

  12. 75 FR 42085 - Workshop To Review Initial Health Effects Draft Materials for the Ozone (O3

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... Materials for the Ozone (O 3 ) Integrated Science Assessment (ISA) AGENCY: Environmental Protection Agency... evaluate initial draft materials for the health effects sections of the O 3 Integrated Science Assessment... of Research and Development (ORD). The workshop will be held on August 6, 2010, in Research Triangle...

  13. Integrated Science Assessment (ISA) for Lead (Second ...

    EPA Pesticide Factsheets

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) has been made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regarding whether the current standards for Pb sufficiently protect public health and the environment. Lead (Pb) is one of six principal (or criteria) pollutants for which EPA has established NAAQS

  14. 77 FR 12579 - Notification of a Public Meeting of the Chartered Science Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ... the Chartered SAB to conduct quality reviews of a draft report on the President's requested FY 2013 budget for EPA research and a draft report on science integration at EPA; to plan for a joint meeting of... receive a briefing on ORD and sustainability science; and to discuss the scientific and technical bases...

  15. 77 FR 1932 - Notification of a Public Teleconference of the Science Advisory Board Committee on Science...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-12

    ... a draft report based on fact-finding activities conducted as part of a study of science integration... Science Advisory Board Committee on Science Integration for Decision Making AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The Environmental Protection Agency (EPA or Agency) Science...

  16. Integrated Science Assessment (ISA) for Sulfur Oxides ...

    EPA Pesticide Factsheets

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regarding whether the current standard for SO2 sufficiently protects public health. Sulfur oxides is one of six principal (or “criteria”) pollutants for which EPA has established national ambient air quality standards (NAAQS).

  17. Integrated Science Assessment (ISA) for Sulfur Oxides ...

    EPA Pesticide Factsheets

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regarding whether the current standard for SO2 sufficiently protects public health. Sulfur oxides is one of six principal (or “criteria”) pollutants for which EPA has established national ambient air quality standards (NAAQS).

  18. 76 FR 68791 - Notice of Availability for Public Comment on the Interagency Ocean Observing Committee Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... NATIONAL SCIENCE FOUNDATION Notice of Availability for Public Comment on the Interagency Ocean Observing Committee Draft Certification Criteria for Non-Federal Asset Integration Into IOOS AGENCY... eligibility for integration into the System and to ensure compliance with all applicable standards and...

  19. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (Second External Review Draft, Dec 2016)

    EPA Science Inventory

    This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of sulfur oxides. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current primar...

  20. Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria (Second External Review Draft, 2015)

    EPA Science Inventory

    This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of oxides of nitrogen. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current ...

  1. Integrated Science Assessment (ISA) for Oxides of Nitrogen, Oxides of Sulfur and Particulate Matter - Ecological Criteria (First External Review Draft, Mar 2017)

    EPA Science Inventory

    This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision on retaining or revising the current secondary standards for NO2, SO2, PM 2.5 and PM 10 since the prior re...

  2. Integrated Science Assessment (ISA) for Carbon Monoxide ...

    EPA Pesticide Factsheets

    EPA announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes was made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA's decision regarding whether the current standards for CO sufficiently protect public health and the environment. The Integrated Plan for Review of the NAAQS for CO {U.S. EPA, 2008 #8615} identifies key policy-relevant questions that provide a framework for this review of the scientific evidence. These questions frame the entire review of the NAAQS, and thus are informed by both science and policy considerations. The ISA organizes and presents the scientific evidence such that it, when considered along with findings from risk analyses and policy considerations, will help the EPA address these questions during the NAAQS review:

  3. RE:RE: Comments on the Draft US EPA Document Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS).

    EPA Pesticide Factsheets

    Letter from the Organic Arsenical Products Task Force expressing concern about aspects of the Science Advisory Board Workgroup's review of a draft document Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS) and decision not to grant more time to prepare for meeting.

  4. 78 FR 70040 - Draft Integrated Science Assessment for Nitrogen Oxides-Health Criteria

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... (NO 2 ). The Integrated Science Assessment (ISA), in conjunction with additional technical and policy... the secondary (welfare-based) NAAQS for NO 2 , in conjunction with a review of the secondary NAAQS for... called an Air Quality Criteria Document). The ISA, in conjunction with additional technical and policy...

  5. 77 FR 6796 - Notification of a Public Meeting of the Clean Air Scientific Advisory Committee (CASAC); Ozone...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ... Scientific Advisory Committee (CASAC); Ozone Review Panel AGENCY: Environmental Protection Agency (EPA... teleconference of the CASAC Ozone Review Panel to discuss its draft review of EPA's Integrated Science Assessment for Ozone and Related Photochemical Oxidants (Second External Review Draft--September 2011). DATES...

  6. 77 FR 64334 - Notification of a Public Teleconference of the Clean Air Scientific Advisory Committee (CASAC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... Air Scientific Advisory Committee (CASAC) Ozone Review Panel AGENCY: Environmental Protection Agency... teleconference of the CASAC Ozone Review Panel to discuss its draft reviews of four EPA documents: Integrated Science Assessment for Ozone and Related Photochemical Oxidants (Third External Review Draft-- June 2012...

  7. Integrated Science Assessment (ISA) for Sulfur Oxides ...

    EPA Pesticide Factsheets

    EPA announced the availability of the external review draft of the Integrated Science Assessment for Sulfur Oxides– Health Criteria for public comment and independent peer review in a November 24, 2015 Federal Register Notice. This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of sulfur oxides. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current primary (health-based) National Ambient Air Quality Standard (NAAQS) for sulfur dioxide. The Integrated Plan for Review of the Primary NAAQS for SOx U.S. 2: EPA (2007) identifies key policy-relevant questions that provide a framework for this review of the scientific evidence. These questions frame the entire review of the NAAQS, and thus are informed by both science and policy considerations. The ISA organizes and presents the scientific evidence such that, when considered along with findings from risk analyses and policy considerations, will help the EPA address these questions in completing the NAAQS review.

  8. 76 FR 64327 - Office of Oceanic and Atmospheric Research Draft Strategic Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... science integrity. Ultimately, this plan provides the framework that OAR will use to deliver significant benefits to society while working to advance NOAA's mission of science, service, and stewardship. Dated...

  9. 76 FR 21346 - Science Advisory Board Staff Office, Notification of a Public Teleconference of the Clean Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... a Public Teleconference of the Clean Air Scientific Advisory Committee (CASAC) Lead Review Panel... (CASAC) Lead Review Panel to provide consultative advice on EPA's draft Integrated Review Plan for the National Ambient Air Quality Standards for Lead (draft IRP). DATES: The public teleconference will be held...

  10. 75 FR 59716 - Draft Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ... environment. Through the IRIS Program, EPA provides the highest quality science- based human health... external review draft human health assessment titled, ``Toxicological Review of Urea: In Support of Summary... register, please indicate if you will need audio-visual equipment (e.g., laptop computer and slide...

  11. IRIS Toxicological Review for Carbon Tetrachloride ...

    EPA Pesticide Factsheets

    EPA released the draft report,Toxicological Review for Carbon Tetrachloride(Interagency Science Discussion Draft), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies and White House Offices are provided below with external peer review panel comments. EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of carbon tetrachloride that will appear on the Integrated Risk Information System (IRIS) database.

  12. Six years after the NRC review of EPA's Draft IRIS Toxicological Review of Formaldehyde: Regulatory implications of new science in evaluating formaldehyde leukemogenicity.

    PubMed

    Mundt, Kenneth A; Gentry, P Robinan; Dell, Linda D; Rodricks, Joseph V; Boffetta, Paolo

    2018-02-01

    Shortly after the International Agency for Research on Cancer (IARC) determined that formaldehyde causes leukemia, the United States Environmental Protection Agency (EPA) released its Draft IRIS Toxicological Review of Formaldehyde ("Draft IRIS Assessment"), also concluding that formaldehyde causes leukemia. Peer review of the Draft IRIS Assessment by a National Academy of Science committee noted that "causal determinations are not supported by the narrative provided in the draft" (NRC 2011). They offered recommendations for improving the Draft IRIS assessment and identified several important research gaps. Over the six years since the NRC peer review, significant new science has been published. We identify and summarize key recommendations made by NRC and map them to this new science, including extended analysis of epidemiological studies, updates of earlier occupational cohort studies, toxicological experiments using a sensitive mouse strain, mechanistic studies examining the role of exogenous versus endogenous formaldehyde in bone marrow, and several critical reviews. With few exceptions, new findings are consistently negative, and integration of all available evidence challenges the earlier conclusions that formaldehyde causes leukemia. Given formaldehyde's commercial importance, environmental ubiquity and endogenous production, accurate hazard classification and risk evaluation of whether exposure to formaldehyde from occupational, residential and consumer products causes leukemia are critical. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  13. 78 FR 2394 - Release of Draft Document Related to the Review of the National Ambient Air Quality Standards for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... technical difficulties and cannot contact you for clarification, the EPA may not be able to consider your... docket number and other identifying information (subject heading, Federal Register date and page number... information presented in the third draft Integrated Science Assessment for Lead \\2\\ and health and ecological...

  14. 76 FR 54227 - Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... found in the environment. Through the IRIS Program, EPA provides the highest quality science-based human... for the external review draft human health assessment titled, ``Toxicological Review of n-Butanol: In... will need audio-visual equipment (e.g., laptop computer and slide projector). In general, each...

  15. Workshop to Obtain Input on Draft Materials for the Integrated Science Assessment (ISA) for Sulfur Oxides (SOx): Health Criteria

    EPA Science Inventory

    As part of the review of the air quality criteria for sulfur oxides (SOX) and primary (health-based) National Ambient Air Quality Standards (NAAQS) for sulfur dioxide (SO2), EPA is announcing a teleconference workshop to evaluate preliminary draft materials ...

  16. 77 FR 22316 - Notification of a Public Teleconference of the Science Advisory Board Ecological Processes and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-13

    ...) document, ``Integrating Ecological Assessment and Decision-Making at EPA, 2011 RAF Ecological Assessment... document, ``Integrating Ecological Assessment and Decision- Making at EPA, 2011 RAF Ecological Assessment... review comments on the EPA RAF draft document ``Integrating Ecological Assessment and Decision-Making at...

  17. Review of the Draft 2014 Science Mission Directorate Science Plan

    NASA Technical Reports Server (NTRS)

    2013-01-01

    At the request of NASA's Science Mission Directorate (SMD), the National Research Council's (NRC's) Space Studies Board (SSB) initiated a study to review a draft of the SMD's 2014 Science Plan. The request for this review was made at a time when NASA is engaged in the final stages of a comprehensive, agency-wide effort to develop a new strategic plan and at a time when NASA's budget is under considerable stress. SMD's Science Plan serves to provide more detail on its four traditional science disciplines-astronomy and astrophysics, solar and space physics (also called heliophysics), planetary science, and Earth remote sensing and related activities-than is possible in the agency-wide Strategic Plan. In conducting its review of the draft Science Plan, the Committee on the Assessment of the NASA Science Mission Directorate 2014 Science Plan was charged to comment on the following specific areas: (1) Responsiveness to the NRC's guidance on key science issues and opportunities in recent NRC reports; (2) Attention to interdisciplinary aspects and overall scientific balance; (3) Identification and exposition of important opportunities for partnerships as well as education and public outreach; (4) Integration of technology development with the science program; (5) Clarity on how the plan aligns with SMD's strategic planning process; (6) General readability and clarity of presentation; and (7) Other relevant issues as determined by the committee. The main body of the report provides detailed findings and recommendations relating to the draft Science Plan. The highest-level, crosscutting issues are summarized here, and more detail is available in the main body of the report.

  18. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 8: Aerothermodynamics Automation and Robotics (A/R) systems sensors, high-temperature superconductivity

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Viewgraphs of briefings presented at the SSTAC/ARTS review of the draft Integrated Technology Plan (ITP) on aerothermodynamics, automation and robotics systems, sensors, and high-temperature superconductivity are included. Topics covered include: aerothermodynamics; aerobraking; aeroassist flight experiment; entry technology for probes and penetrators; automation and robotics; artificial intelligence; NASA telerobotics program; planetary rover program; science sensor technology; direct detector; submillimeter sensors; laser sensors; passive microwave sensing; active microwave sensing; sensor electronics; sensor optics; coolers and cryogenics; and high temperature superconductivity.

  19. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 8: Aerothermodynamics Automation and Robotics (A/R) systems sensors, high-temperature superconductivity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Viewgraphs of briefings presented at the SSTAC/ARTS review of the draft Integrated Technology Plan (ITP) on aerothermodynamics, automation and robotics systems, sensors, and high-temperature superconductivity are included. Topics covered include: aerothermodynamics; aerobraking; aeroassist flight experiment; entry technology for probes and penetrators; automation and robotics; artificial intelligence; NASA telerobotics program; planetary rover program; science sensor technology; direct detector; submillimeter sensors; laser sensors; passive microwave sensing; active microwave sensing; sensor electronics; sensor optics; coolers and cryogenics; and high temperature superconductivity.

  20. 76 FR 38650 - Draft Integrated Science Assessment for Lead

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... Science Assessment for Lead AGENCY: Environmental Protection Agency. ACTION: Notice of extension of public... Lead'' (EPA/600/R-10/075A). The original Federal Register notice announcing the public comment period... review of the National Ambient Air Quality Standards (NAAQS) for Lead. DATES: The public comment period...

  1. 76 FR 36094 - Draft NOAA Scientific Integrity Policy and Handbook; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ..., Deputy Chief Financial Officer, Office of Oceanic and Atmospheric Research, National Oceanic and... the key role of science in informing policy; Encourages scientists to publish data and findings to...

  2. 75 FR 48731 - Notice of Availability for Public Comment on the Draft Joint Subcommittee on Ocean Science and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ..., the academic community and the private sector in providing IOOS environmental information, products... Subcommittee on Ocean Science and Technology--Interagency Ocean Observation Committee Public-Private Use Policy... a 60-day public comment period for the Public-Private Use Policy mandated by the Integrated Coastal...

  3. Draft material : enhanced freight movement at domestic and international gateways

    DOT National Transportation Integrated Search

    1997-07-01

    The purpose of this report is to provide a framework for integrating the core program activities that constitute the National Science and Technology Councils (NSTCs) public-private initiative to improve freight movement at domestic and internat...

  4. 77 FR 61573 - Science Advisory Board Satellite Task Force; Availability of Draft Report and Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ...-2506-01] RIN 0648-XC276 Science Advisory Board Satellite Task Force; Availability of Draft Report and... notice on behalf of the NOAA Science Advisory Board (SAB) to announce the availability of the draft..., 2012. ADDRESSES: The Draft Report of the SATTF will be available on the NOAA Science Advisory Board Web...

  5. IRIS Toxicological Review of Ammonia (Revised External ...

    EPA Pesticide Factsheets

    In August 2013, EPA submitted a revised draft IRIS assessment of ammonia to the agency's Science Advisory Board (SAB) and posted this draft on the IRIS website. EPA had previously released a draft of the assessment for public comment, held a public meeting about the draft, and then revised it based on the comments received. The SAB CAAC-Ammonia panel will review this draft assessment. Details about the meeting dates, times, and location are available via the Federal Register Notice posted on March 25, 2014. The SAB provided information on how the public can participate in the external peer review meetings, as well as instructions about how to provide comments to the SAB in the notice. Additional information on the SAB review of ammonia is on the SAB website. Report Information: The Toxicological Review of Ammonia was originally released for a 60-day public comment period on June 8, 2012. [Federal Register Notice Jun 8, 2012] EPA revised the toxicological review in response to the public comments received. EPA has released the revised external review draft ammonia assessment and the SAB CAAC is conducting a peer review of the scientific basis supporting the assessment that will appear in the Integrated Risk Information System (IRIS) database. Information regarding the peer review can be found at the SAB review of ammonia website. EPA is undertaking an Integrated Risk Information System (IRIS) health assessment for ammonia. IRIS is an EPA database cont

  6. Integrated Science Assessment (ISA) for Oxides of Nitrogen ...

    EPA Pesticide Factsheets

    EPA is announcing the availability of the First External Review Draft of the Integrated Science Assessment for Oxides of Nitrogen – Health Criteria for public comment and independent peer review. This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of oxides of nitrogen. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current primary (health-based) national ambient air quality standards for nitrogen dioxide. The Clean Air Act (CAA) requires EPA to periodically review and revise, as appropriate, existing air quality criteria and NAAQS. The CAA also requires an independent scientific committee to review the criteria and to advise the Administrator regarding any recommended revisions to the existing criteria and standards, as may be appropriate. The Clean Air Scientific Advisory Committee (CASAC) of EPA’s Science Advisory Board serves as this independent scientific committee. The ISA is one of the four major elements of the NAAQS review process that will inform the Agency’s final decisions; other components of the process are an integrated plan highlighting the key policy-relevant issues; a risk/exposure assessment if warranted; and an advance notice of proposed rulemaking (ANPRM) reflecting the Agency’s views regarding options to retain or revise the NO2 NAAQS based on the evaluation of key information cont

  7. IRIS Toxicological Review of Carbon Tetrachloride (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of carbon tetrachloride that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and...

  8. 77 FR 5247 - Draft Integrated Science Assessment for Lead

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... to identify certain pollutants, which among other things, ``cause or contribute to air pollution... other things) with independent scientific review of EPA's air quality criteria. On February 26, 2010 (75..., are publicly available only in hard copy. Publicly available docket materials are available either...

  9. IRIS Toxicological Review of Inorganic Arsenic (Cancer) (2010 External Review Draft)

    EPA Science Inventory

    EPA's Science Advisory Board (SAB) conducted a review of the scientific basis supporting the human health cancer hazard and dose-response assessment of inorganic arsenic that will appear on the Integrated Risk Information System (IRIS) database. EPA revised the assessment and is...

  10. IRIS Toxicological Review of Bromobenzene (External Review Draft)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of Bromobenzene that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and app...

  11. IRIS Toxicological Review of Acrylamide (External Review Draft)

    EPA Science Inventory

    EPA has conducted a peer review by EPA’s Science Advisory Board (SAB) of the scientific basis supporting the human health hazard and dose-response assessment of acrylamide that once finalized will appear on the Integrated Risk Information System (IRIS) database. Peer review is m...

  12. IRIS Toxicological Review of Tetrachloroethylene (Perchloroethylene) (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of tetrachloroethylene that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and ...

  13. IRIS Toxicological Review of Nitrobenzene (External Review Draft)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessments of nitrobenzene, that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and a...

  14. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (Etbe) ...

    EPA Pesticide Factsheets

    In September 2016, the U.S. Environmental Protection Agency's (USEPA) released the draft Integrated Risk Information System (IRIS) Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE). Consistent with the 2013 IRIS Enhancements, draft IRIS assessments are released prior to external peer review for a 60-day public comment period and discussed at an upcoming public science meeting. Accordingly, the toxicological review, supplementary information, and other materials pertaining to this draft assessment are posted on this site. This material is being released for public viewing and comment prior to a public meeting, providing an opportunity for the IRIS Program to engage in early discussions with stakeholders and the public on data that may be used to identify adverse health effects and characterize exposure-response relationships.

  15. IRIS Toxicological Review for Carbon Tetrachloride (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA released the draft report,Toxicological Review for Carbon Tetrachloride(Interagency Science Discussion Draft), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Co...

  16. Career Education Resource Guide for Biology. Working Draft.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge.

    The resource guide integrates learning activities in biological science with an exploration of careers in biology or related fields. The materials are divided into seven units: tools of the scientist, basis for life, diversity (protists, plants, animals), structure and function, continuity (reproduction, development, and genetics), evolution, and…

  17. IRIS Toxicological Review of 2-Hexanone (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 2-hexanone that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and appro...

  18. IRIS Toxicological Review of Dibutyl Phthalate (DBP) (External Review Draft) 2006

    EPA Science Inventory

    The U.S. EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of dibutyl phthalate that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used cr...

  19. 77 FR 70776 - Draft Integrated Science Assessment for Lead

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-27

    ... certain pollutants which, among other things, ``cause or contribute to air pollution, which may reasonably... available only in hard copy. Publicly available docket materials are available either electronically in www.regulations.gov or in hard copy at the OEI Docket in the EPA Headquarters Docket Center. Dated: September 28...

  20. 76 FR 10893 - Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... Oxidants'' will be available primarily via the Internet on the National Center for Environmental Assessment... Administrator to identify certain pollutants which, among other things, ``cause or contribute to air pollution... Clean Air Act, is charged (among other things) with independent scientific review of EPA's air quality...

  1. IRIS Toxicological Review of Libby Amphibole Asbestos (Interagency Science Discussion Draft)

    EPA Science Inventory

    On August 25, 2011, the draft assessment of Libby Amphibole asbestos was released for external peer review and public comment. The draft assessment was revised based on peer review comments from EPA’s Science Advisory Board (SAB) and public comments. The revised draft was review...

  2. Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (2011 Interagency Science Discussion Draft)

    EPA Science Inventory

    On September 22, 2006, the draft Evaluation of the Carinogenicity of Ethylene Oxide (EPA/635/R-06/003) and the draft charge to external peer reviewers were released for external peer review and public comment. This draft was reviewed by EPA’s Science Advisory Board (SAB)...

  3. 77 FR 46755 - Notification of a Public Meeting of the Clean Air Scientific Advisory Committee (CASAC) Ozone...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-06

    ... Scientific Advisory Committee (CASAC) Ozone Review Panel AGENCY: Environmental Protection Agency (EPA... the CASAC Ozone Review Panel to conduct a peer review of EPA's Integrated Science Assessment for Ozone... Assessment for Ozone--First External Review Draft (July 2012), Welfare Risk and Exposure Assessment for Ozone...

  4. 78 FR 26026 - Draft Plan for Development of the Integrated Science Assessment for Nitrogen Oxides-Health Criteria

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-03

    ... pollutants, which among other things, ``cause or contribute to air pollution, which may reasonably be...) of the Clean Air Act, is charged (among other things) with independent scientific review of EPA's air..., such as copyrighted material, are publicly available only in hard copy. Publicly available docket...

  5. IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR BORON AND COMPOUNDS (THIRD EXTERNAL REVIEW DRAFT 2002)

    EPA Science Inventory

    The U. S. EPA has conducted a peer review of the scientific basis supporting the health hazard and dose response assessment for Boron that will appear on the Agency's online data base, the Integrated Risk Information System (IRIS). Peer Review is meant to ensure that science is u...

  6. RE: Notification of SAB Workgroup Public Meeting for the Toxicological Review of Inorganic Arsenic

    EPA Pesticide Factsheets

    Request from the Organic Arsenical Products Task Force for the Science Advisory Board to reschedule the public meeting of a workgroup to conduct a review of the draft document Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS).

  7. 77 FR 36534 - Third External Review Draft Integrated Science Assessment for Ozone and Related Photochemical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... the Internet on the National Center for Environmental Assessment's home page under the Recent... which, among other things, ``cause or contribute to air pollution which may reasonably be anticipated to... Clean Air Act, is charged (among other things) with independent scientific review of EPA's air quality...

  8. IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR 1,1,1-TRICHLOROETHANE (EXTERNAL REVIEW DRAFT)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,1,1-trichloroethane that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibl...

  9. Integrated Science Assessment (ISA) for Sulfur Oxides ...

    EPA Pesticide Factsheets

    This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of sulfur oxides. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current primary (health-based) National Ambient Air Quality Standard (NAAQS) for sulfur dioxide. The references considered for inclusion in or cited in the external review draft ISA are available at https://hero.epa.gov/hero/sulfur-oxides. The intent of the ISA, according to the CAA, is to “accurately reflect the latest scientific knowledge expected from the presence of [a] pollutant in ambient air” (U.S. Code, 1970a, 1970b). It includes an assessment of scientific research from atmospheric sciences, exposure sciences, dosimetry, mode of action, animal and human toxicology, and epidemiology. Key information and judgments formerly found in the Air Quality Criteria Documents (AQCDs) for sulfur oxides (SOx) are included; Annexes provide additional details supporting the ISA. Together, the ISA and Annexes serve to update and revise the last SOx ISA which was published in 2008.

  10. Nitrogen Oxides (NOx) Primary NAAQS REVIEW: Integrated ...

    EPA Pesticide Factsheets

    The NOx Integrated Review Plan is the first document generated as part of the National Ambient Air Quality Standards (NAAQS) review process. The Plan presents background information, the schedule for the review, the process to be used in conducting the review, and the key policy-relevant science issues that will guide the review. The integrated review plan also discusses the frameworks for the various assessment documents to be prepared by the EPA as part of the review, including an Integrated Science Assessment (ISA), and as warranted, a Risk/Exposure Assessment (REA), and a Policy Assessment (PA). The primary purpose of the NOx Integrated Review Plan is to highlight the key policy-relevant issues to be considered in the Review of the NO2 primary NAAQS. A draft of the integrated review plan will be the subject of an advisory review with the Clean Air Scientific Advisory Committee (CASAC) and made available to the public for review and comment.

  11. Sulfur Dioxide (SO2) Primary NAAQS Review: Integrated ...

    EPA Pesticide Factsheets

    The SO2 Integrated Review Plan is the first document generated as part of the National Ambient Air Quality Standards (NAAQS) review process. The Plan presents background information, the schedule for the review, the process to be used in conducting the review, and the key policy-relevant science issues that will guide the review. The integrated review plan also discusses the frameworks for the various assessment documents to be prepared by the EPA as part of the review, including an Integrated Science Assessment (ISA), and as warranted, a Risk/Exposure Assessment (REA), and a Policy Assessment (PA). The primary purpose of the SO2 Integrated Review Plan is to highlight the key policy-relevant issues to be considered in the Review of the SO2 primary NAAQS. A draft of the integrated review plan will be the subject of an advisory with the Clean Air Scientific Advisory Committee (CASAC) and made available to the public for review and comment.

  12. Redmedial Action, Decision Document, Leaseback Area, Alabama Army Ammunition Plant

    DTIC Science & Technology

    1988-02-01

    Draft Report, Environmental Science and Engineering, Inc. (ESE), 1980. o Final Report for the Alabama Army Ammunition Plant, Leaseback Area...Requirements for the GSA and Leaseback Areas at the AAAP, Draft Report. Environmental Science and Engineering, Inc.(ESE), 1980. o Alabama Army...Ammunition Plant, Feasibility Study, Draft Report, Environmental Science and Engineering, Inc. (ESE), 1986. o Environmental Survey of Alabama Army Ammunition

  13. 76 FR 20347 - Release of Draft Integrated Review Plan for the National Ambient Air Quality Standards for Lead

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... you submit. If EPA cannot read your comment due to technical difficulties and cannot contact you for... rulemaking by docket number and other identifying information (subject heading, Federal Register date and... phase for the review. This phase began with a science policy workshop to identify issues and questions...

  14. 77 FR 34039 - Draft Toxicological Review of Ammonia: In Support of the Summary Information in the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... prepared by the National Center for Environmental Assessment (NCEA) within the EPA Office of Research and... not represent and should not be construed to represent Agency policy or views. EPA's Science Advisory... database (available on the Internet at http://www.epa.gov/iris ) contains qualitative and quantitative...

  15. 76 FR 35216 - Science Advisory Board Staff Office Notification of a Public Teleconference of the Chartered...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-16

    ...The EPA Science Advisory Board (SAB) Staff Office announces a public teleconference of the chartered SAB on July 5, 2011 to conduct a quality review of a draft SAB report, Review of EPA's Draft Hydraulic Fracturing Study Plan (Quality Review Draft).

  16. IRIS Toxicological Review of Ammonia (Interagency Science ...

    EPA Pesticide Factsheets

    On June 1, 2012, the draft Toxicological Review of Ammonia and the draft charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science consultation materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Ammonia and the charge to external peer reviewers, are posted on this site. EPA is undertaking an Integrated Risk Information System (IRIS) health assessment for ammonia. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment paradigm, i.e., hazard identification and dose-response evaluation. IRIS assessments are used in combination with specific situational exposure assessment information to evaluate potential public health risk associated with environmental contaminants.

  17. IRIS Toxicological Review of Benzo[a]pyrene (Interagency ...

    EPA Pesticide Factsheets

    On August 21, 2013, the draft Toxicological Review of Benzo[a]pyrene and the draft charge to external peer reviewers were released for public review and comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science consultation materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Benzo[a]pyrene and the charge to external peer reviewers, are posted on this site. EPA is undertaking an update of the Integrated Risk Information System (IRIS) health assessment for benzo[a]pyrene (BaP). The outcome of this project is an updated Toxicological Review and IRIS Summary for BaP that will be entered into the IRIS database.

  18. Practice of Regulatory Science (Drug Development).

    PubMed

    Kawanishi, Toru

    2017-01-01

    The practice of regulatory science (RS) for drug development is described. In the course material for education in pharmaceutical sciences drafted by the RS Division of the Pharmaceutical Society of Japan, RS for pharmaceuticals is defined as the science of predicting, assessing, and judging the quality, efficacy, and safety of pharmaceutical products throughout their lifespan. RS is also described as an integrated science based on basic and applied biomedical sciences, including analytical chemistry, biochemistry, pharmacology, toxicology, genetics, biostatistics, epidemiology, and clinical trial methodology, and social sciences such as decision science, risk assessment, and communication science. The involvement of RS in drug development generally starts after the optimization of lead compounds. RS plays important roles governing pharmaceuticals during their entire life cycle management phase as well as the drug development phase.

  19. IRIS Toxicological Review of Urea (Final Report) | Science ...

    EPA Pesticide Factsheets

    EPA has finalized the Toxicological Review of Urea: in support of the Integrated Risk Information System (IRIS). Now final, this assessment may be used by EPA’s program and regional offices to inform decisions to protect human health. The draft Toxicological Review of Urea provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to Urea.

  20. Integrated Science Assessment (ISA) for Carbon Monoxide ...

    EPA Pesticide Factsheets

    EPA announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes was made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA's decision regarding whether the current standards for CO sufficiently protect public health and the environment. Section 108(a) of the Clean Air Act directs the EPA Administrator to identify certain pollutants that “cause or contribute to air pollution which may reasonably be anticipated to endanger public health or welfare” and to issue air quality criteria for them. These air quality criteria are to “accurately reflect the latest scientific knowledge useful in indicating the kind and extent of all identifiable effects on public health or welfare which may be expected from the presence of such pollutant in the ambient air….” Under section 109 of the Act, EPA is to establish national ambient air quality standards (NAAQS) for each pollutant for which EPA has issued criteria. Section 109(d) of the Act requires periodic review and, if appropriate, revision of existing air quality criteria to reflect advances in scientific knowledge on the effects of the pollutant on public health or welfare. EPA is also to revise the NAAQS, if appropriate, based on the revised air quality criteria.

  1. IRIS Toxicological Review of Ammonia (Revised External Review Draft)

    EPA Science Inventory

    In August 2013, EPA submitted a revised draft IRIS assessment of ammonia to the agency's Science Advisory Board (SAB) and posted this draft on the IRIS website. EPA had previously released a draft of the assessment for public comment, held a public meeting about the draft, and ...

  2. 76 FR 22394 - Science Advisory Board Staff Office; Notification of a Public Teleconferences of the Science...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-21

    ...The Environmental Protection Agency (EPA or Agency) Science Advisory Board (SAB) Staff Office announces two public teleconferences of the SAB Panel to discuss its draft report of the review of EPA's Draft Hydraulic Fracturing Study Plan.

  3. IRIS Toxicological Review of Acrylamide (External Review ...

    EPA Pesticide Factsheets

    EPA has conducted a peer review by EPA’s Science Advisory Board (SAB) of the scientific basis supporting the human health hazard and dose-response assessment of acrylamide that once finalized will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that the science is used credibly and appropriately in derivation of the dose-response assessments and toxicological characterization. The draft Toxicological Review of Acrylamide provides scientific support and rationale for the hazard identification and dose-response assessment pertaining to a chronic exposure to acrylamide.

  4. NOx SOx Secondary NAAQS: Integrated Review Plan ...

    EPA Pesticide Factsheets

    The NOx SOx Secondary NAAQS Integrated Review Plan is the first document generated as part of the National Ambient Air Quality Standards (NAAQS) review process. The Plan presents background information, the schedule for the review, the process to be used in conducting the review, and the key policy-relevant science issues that will guide the review. The integrated review plan also discusses the frameworks for the various assessment documents to be prepared by the EPA as part of the review, including an Integrated Science Assessment (ISA), and as warranted, a Risk/Exposure Assessment (REA), and a Policy Assessment (PA). The primary purpose of the NOx SOx Secondary NAAQS Integrated Review Plan is to highlight the key policy-relevant issues to be considered in the Review of the Oxides of Nitrogen and Oxides of Sulfur Secondary NAAQS. A draft of the integrated review plan will be the subject of an advisory review with the Clean Air Scientific Advisory Committee (CASAC) and made available to the public for review and comment.

  5. 76 FR 11456 - Science Advisory Board Staff Office; Notification of a Public Meeting of the Chartered Science...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ...) Staff Office announces a public meeting of the Chartered SAB to consider a draft report commenting on... will hold a public meeting to consider a draft report on the President's requested FY 2012 budget for... discuss the work group's draft report and reach agreement on comments to provide the EPA Administrator and...

  6. 77 FR 21772 - Notification of Two Public Teleconferences of the Science Advisory Board Biogenic Carbon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... the Panel's draft report on EPA's draft Accounting Framework for Biogenic CO2 Emissions from...'s draft report on EPA's draft Accounting Framework for Biogenic CO2 Emissions from Stationary... Radiation requested SAB review of EPA's draft accounting framework. As noticed in 76 FR 61100-61101, the SAB...

  7. EPA's 2007 Report on the Environment: Science Report (Sab Review Draft)

    EPA Science Inventory

    The EPA's 2007 Report on the Environment: Science Report (SAB Review Draft), formally known as the EPA's Report on the Environment - Technical Document, was released for public review and comment prior to the Science Advisory Board's (SAB) meeting and review held in July 2007. Co...

  8. 75 FR 62433 - Notice of Public Hearings and the Availability of a Draft Programmatic Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-08

    ... NATIONAL SCIENCE FOUNDATION Notice of Public Hearings and the Availability of a Draft Programmatic Environmental Impact Statement/Overseas Environmental Impact Statement (PEIS/OEIS) AGENCY: National Science... Seismic Research Funded by the National Science Foundation (NSF) or Conducted by the U.S. Geological...

  9. IRIS Toxicological Review of Methanol (Noncancer) (Interagency Science Discussion Draft)

    EPA Science Inventory

    On May 3, 2013, the Toxicological Review of Methanol (noncancer) (Revised External Review Draft) was posted for public review and comment. Subsequently, the draft Toxicological Review, Appendices, and draft IRIS Summary were reviewed internally by EPA and by other federal agenci...

  10. IRIS Toxicological Review of Tert-Butyl Alcohol (Tert-Butanol) ...

    EPA Pesticide Factsheets

    On April 29, 2016, the Toxicological Review of tert-Butyl Alcohol (tert-Butanol) (Public Comment Draft) was released for public comment. The draft Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and the Executive Office of the President during Step 3 (Interagency Science Consultation) before public release. As part of the IRIS process, all written interagency comments on IRIS assessments will be made publicly available. Accordingly, interagency comments with EPA's response and the interagency science consultation drafts of the IRIS Toxicological Review of tert-Butanol and charge to external peer reviewers are posted on this site. EPA is undertaking a new health assessment for t-butyl alcohol (tert-butanol) for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS and IRIS Summary of TBA that will be entered on the IRIS database. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information to evaluate potential public health risks associated with environmental contaminants. The IRIS database is relied on for the development of risk assessments, site-specific environmental decisions, and rule making.

  11. 76 FR 50729 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Chartered...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ... SAB report, Peer Review of EPA's Draft National-Scale Mercury Risk Assessment (08/04/11) Draft. DATES... SAB draft report entitled Peer Review of EPA's Draft National-Scale Mercury Risk Assessment (08/04/1...)(1)(A) of the Clean Air Act (CAA). EPA developed a draft risk assessment for mercury, entitled...

  12. 76 FR 4660 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Science...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... a Public Teleconference of the Science Advisory Board Lead Review Panel AGENCY: Environmental... a public teleconference of the SAB Lead Review Panel to discuss its draft advisory report concerning... (November 2010 Draft). DATES: The SAB Lead Review Panel will conduct a public teleconference on February 22...

  13. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5 ...

    EPA Pesticide Factsheets

    On March 10, 2016, the public comment draft Toxicological Review of Hexahydro-1,3,5-trinitro-1,3,5-triazine and the draft charge to external peer reviewers were released for public review and comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science consultation materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Hexahydro-1,3,5-trinitro-1,3,5-triazine and the charge to external peer reviewers, are posted on this site. EPA is undertaking an update of the Integrated Risk Information System (IRIS) health assessment for RDX. The outcome of this project is an updated Toxicological Review and IRIS Summary for RDX that will be entered into the IRIS database.

  14. IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (Interagency Science Consultation Draft)

    EPA Science Inventory

    On March 31, 2010, the draft IRIS Toxicological Review of Dichloromethane (Methylene Chloride) external review draft document and the charge to external peer reviewers were released for public review and comment. The draft document and the charge to external peer reviewers were r...

  15. IRIS Toxicological Review of Trimethylbenzenes (Revised External Review Draft)

    EPA Science Inventory

    In August 2013, EPA submitted a revised draft IRIS assessment of trimethylbenzenes to the agency's Science Advisory Board (SAB) and posted this draft on the IRIS website. EPA had previously released a draft of the assessment for public comment, held a public meeting about the dr...

  16. IRIS Toxicological Review of Inorganic Arsenic (Cancer) (Interagency Science Consultation Draft)

    EPA Science Inventory

    On February 19, 2010, the draft IRIS Toxicological Review of Inorganic Arsenic (Cancer) external review draft document and the charge to external peer reviewers were released for public review and comment. The draft document and the charge to external peer reviewers were reviewed...

  17. Integrated Science Assessment (ISA) for Oxides of Nitrogen ...

    EPA Pesticide Factsheets

    EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Oxides of Nitrogen and Sulfur - Environmental Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA's decision on retaining or revising the current secondary standards for NO2 and SO2. The current secondary NAAQS for SOX, set in 1973, is a 3-h average 0.5 ppm of SO2, not to be exceeded more than once per year. The secondary NOX NAAQS is identical to the primary standard set in 1971: 0.053 ppm NO2 as an annual average. These secondary standards are intended to protect against direct damage to vegetation by exposure to gas-phase NOX or SOX. Acute and chronic exposures to SO2 can have phytotoxic effects on vegetation, such as foliar injury, decreased photosynthesis and decreased growth. Similarly, exposure to sufficient concentrations of NO2, NO, PAN, and HNO3 can cause foliar injury, decreased photosynthesis and decreased growth. In addition, these gas-phase NOX may contribute to N saturation in some areas of the U.S. There is little new evidence overall for direct effects of exposure to gas-phase NOX or SOX on vegetation at current concentrations. However, there is some evidence that vegetation in regions with high concentrations of photochemical oxidants may be affected by HN

  18. IRIS Toxicological Review of Hexachloroethane (Interagency Science Consultation Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Hexachloroethane, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies a...

  19. EPA Releases Draft Policy to Reduce Animal Testing for Skin Sensitization

    EPA Pesticide Factsheets

    The document, Draft Interim Science Policy: Use of Alternative Approaches for Skin Sensitization as a Replacement for Laboratory Animal Testing, describes the science behind the non-animal alternatives that can now be used to identify skin sensitization.

  20. IRIS Toxicological Review of Trichloroethylene (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Trichloroethylene, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies ...

  1. 77 FR 76000 - Notice of Availability of Draft Report of the NOAA Research and Development Portfolio Review Task...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration (NOAA), Science Advisory... of the NOAA Science Advisory Board (SAB) to announce the availability of the draft report of the SAB... will be available on the NOAA Science Advisory Board Web site at: http://www.sab.noaa.gov/Reports/prtf...

  2. IRIS Toxicological Review of Ammonia Noncancer Inhalation ...

    EPA Pesticide Factsheets

    In September 2016, EPA finalized the IRIS assessment of Ammonia (Noncancer Inhalation). The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices before public release in June 2016. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science discussion materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Ammonia (Noncancer Inhalation) are posted on this site. Note: No major science comments were received on the Interagency Science Discussion Draft. EPA is undertaking an Integrated Risk Information System (IRIS) health assessment for ammonia. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment paradigm, i.e., hazard identification and dose-response evaluation. IRIS assessments are used in combination with specific situational exposure assessment information to evaluate potential public health risk associated with environmental contaminants.

  3. IRIS TOXICOLOGICAL REVIEW OF TETRACHLOROETHYLENE (PERCHLOROETHYLENE) (INTERAGENCY SCIENCE DISCUSSION DRAFT)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Tetrachloroethylene (Perchloroethylene), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment...

  4. IRIS Toxicological Review of Biphenyl (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Biphenyl, that was distributed to other federal agencies and the Executive Office of the President for comment during Interagency Science Discussion (IASD) (Step 6b) of the IRIS assessment development process. Interagenc...

  5. 78 FR 78063 - Appendix 4 to Draft Qualitative Risk Assessment of Risk of Activity/Food Combinations for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ...ScienceResearch/UCM334110.pdf . 2. FDA, ``Appendix 4 to Draft Qualitative Risk Assessment of Risk of....regulations.gov and at http://www.fda.gov/downloads/Food/FoodScienceResearch/RiskSafetyAssessment/UCM377408... on a Farm,'' 2013. Available at: http://www.fda.gov/downloads/Food/FoodScienceResearch/RiskSafety...

  6. IRIS Toxicological Review of Chloroprene (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Chloroprene, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Co...

  7. IRIS Toxicological Review of Hexachloroethane (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Hexachloroethane, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Pro...

  8. IRIS Toxicological Review of Pentachlorophenol (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Pentachlorophenol, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Pr...

  9. 75 FR 69475 - Notice Regarding Changed Venue for Public Hearing On a Draft Programmatic Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-12

    ... NATIONAL SCIENCE FOUNDATION Notice Regarding Changed Venue for Public Hearing On a Draft Programmatic Environmental Impact Statement/Overseas Environmental Impact Statement (PEIS) AGENCY: National Science Foundation. ACTION: Notice regarding changed venue for public hearing. SUMMARY: The National...

  10. IRIS Toxicological Review for Acrylamide (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review for Acrylamide, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process<...

  11. 78 FR 52764 - Extension of Public Comment Period Hydrogen Energy California's Integrated Gasification Combined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-26

    ... DEPARTMENT OF ENERGY Extension of Public Comment Period Hydrogen Energy California's Integrated Gasification Combined Cycle Project Preliminary Staff Assessment and Draft Environmental Impact Statement... California's Integrated Gasification Combined Cycle Project Preliminary Staff Assessment/Draft Environmental...

  12. IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Dichloromethane, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Proc...

  13. IRIS Toxicological Review of Tetrahydrofuran (THF) (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Tetrahydrofuran, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Proc...

  14. IRIS Toxicological Review of Urea (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Urea,, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. C...

  15. Producibility Engineering and Planning (PEP)

    DTIC Science & Technology

    1977-01-01

    Materiel System, May 1976. c. Cesare Raimondi, "Estimating Drafting Time - Art , Science , Guess- work", Machine Design, 7 September 1972. d. Current Wage...Comprehensive 8 16 24 32 40 86 45 70 90 80 1/ Cesare Raimondi, "Estimating Drafting Time- Art , Science , Guesswork," Machine Design, September

  16. IRIS Toxicological Review of Trichloroacetic Acid (TCA) (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Trichloroacetic Acid (TCA), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development ...

  17. 78 FR 54640 - Extension of Public Comment Period Hydrogen Energy California's Integrated Gasification Combined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... DEPARTMENT OF ENERGY Extension of Public Comment Period Hydrogen Energy California's Integrated Gasification Combined Cycle Project Preliminary Staff Assessment and Draft Environmental Impact Statement... Integrated Gasification Combined Cycle Project Preliminary Staff Assessment and Draft Environmental Impact...

  18. 75 FR 1617 - Draft Toxicological Review of Methanol: In Support of the Summary Information in the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... on the Integrated Risk Information System (IRIS)'' (EPA/635/R-09/013). The draft document was... ``Toxicological Review of Methanol: In Support of Summary Information on the Integrated Risk Information System... Toxicological Review of Methanol: In Support of the Summary Information in the Integrated Risk Information...

  19. 75 FR 69065 - Draft Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... Summary Information on the Integrated Risk Information System (IRIS) AGENCY: Environmental Protection..., ``Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk Information System (IRIS...: The draft ``Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk...

  20. 76 FR 3133 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Science...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-19

    ... document (TSD), Methods and Approaches for Deriving Numeric Criteria for Nitrogen/Phosphorus Pollution in Florida's Estuaries, Coastal Waters, and Southern Inland Flowing Waters. The draft TSD describes methods... discuss its draft report reviewing EPA's technical support document on development of numeric nutrient...

  1. IRIS Toxicological Review of Ethylene Glycol Mono-Butyl Ether (Egbe) (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA released the draft report, Toxicological Review for Ethylene Glycol Mono-Butyl Ether , that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from ot...

  2. 75 FR 1790 - Draft Guidance for Institutional Review Boards, Clinical Investigators, and Sponsors: IRB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ....gov/ScienceResearch/SpecialTopics/RunningClinicalTrials/ProposedRegulationsandDraftGuidances/default...] Draft Guidance for Institutional Review Boards, Clinical Investigators, and Sponsors: IRB Continuing Review After Clinical Investigation Approval; Availability AGENCY: Food and Drug Administration, HHS...

  3. Health Assessment Document for Diesel Emissions (External Review Draft)

    EPA Science Inventory

    This revised draft assessment of the possible health hazards from human exposure to diesel engine exhaust emissions updates two earlier drafts (1998 and 1994) that were reviewed by the Agency's Science Advisory Board (SAB) Clean Air Scientific Advisory Committee (CASAC). The curr...

  4. Health Assessment Document for Diesel Exhaust (Revised External Review Draft)

    EPA Science Inventory

    This External Review Draft version of this assessment updates three earlier drafts (1999, 1998 and 1994) that were reviewed by the Clean Air Scientific Advisory Committee (CASAC) of the Agency's Science Advisory Board (SAB). The assessment characterizes the possible human healt...

  5. Project TIMS (Teaching Integrated Math/Science)

    NASA Technical Reports Server (NTRS)

    Edwards, Leo, Jr.

    1993-01-01

    The goal of this project is to increase the scientific knowledge and appreciation bases and skills of pre-service and in-service middle school teachers, so as to impact positively on teaching, learning, and student retention. This report lists the objectives and summarizes the progress thus far. Included is the working draft of the TIMS (Teaching Integrated Math/Science) curriculum outline. Seven of the eight instructional subject-oriented modules are also included. The modules include informative materials and corresponding questions and educational activities in a textbook format. The subjects included here are the universe and stars; the sun and its place in the universe; our solar system; astronomical instruments and scientific measurements; the moon and eclipses; the earth's atmosphere: its nature and composition; and the earth: directions, time, and seasons. The module not included regards winds and circulation.

  6. IRIS Toxicological Review of Trimethylbenzenes (Interagency Science Consultation Draft)

    EPA Science Inventory

    On June 26, 2012, the draft Toxicological Review of Trimethylbenzenes and the draft charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and W...

  7. California Diploma Project Technical Report II: Alignment Study--Alignment Study of the Health Sciences and Medical Technology Draft Standards and California's Exit Level Common Core State Standards

    ERIC Educational Resources Information Center

    McGaughy, Charis; de Gonzalez, Alicia

    2012-01-01

    The California Department of Education is in the process of revising the Career and Technical Education (CTE) Model Curriculum Standards. The Educational Policy Improvement Center (EPIC) conducted an investigation of the draft version of the Health Sciences and Medical Technology Standards (Health Science). The purpose of the study is to…

  8. 75 FR 26269 - Draft Programmatic Environmental Assessment for the Integrated Public Alert and Warning Program's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ...] Draft Programmatic Environmental Assessment for the Integrated Public Alert and Warning Program's... from construction- related actions taken under the Integrated Public Alert and Warning Program (IPAWS... Order 13407, Public Alert and Warning System, by providing robust and survivable power generation, fuel...

  9. 76 FR 55390 - Guidance on Exculpatory Language in Informed Consent, Draft

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ...://www.fda.gov/ScienceResearch/SpecialTopics/RunningClinicalTrials/default.htm , is intended to assist... , http://www.hhs.gov/ohrp/newsroom/rfc/index.html , or http://www.fda.gov/ScienceResearch/SpecialTopics/RunningClinicalTrials/default.htm . III. Request for Comments OHRP and FDA are making their joint draft...

  10. IRIS Toxicological Review of 1,1,2,2-Tetrachloroethane (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of 1,1,2,2-Tetrachloroethane, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Develo...

  11. IRIS Toxicological Review of cis- & trans-1,2-Dichloroethylene (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of cis-1,2-Dichloroethylene and trans-1,2-Dichloroethylene, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the A Space-Based Point Design for Global Coherent Doppler Wind Lidar Profiling Matched to the Recent NASA/NOAA Draft Science Requirements

    NASA Technical Reports Server (NTRS)

    Kavaya, Michael J.; Emmitt, G. David; Frehlich, Rod G.; Amzajerdian, Farzin; Singh, Upendra N.

    2002-01-01

    An end-to-end point design, including lidar, orbit, scanning, atmospheric, and data processing parameters, for space-based global profiling of atmospheric wind will be presented. The point design attempts to match the recent NASA/NOAA draft science requirements for wind measurement.

  12. IRIS Toxicological Review of Hydrogen Cyanide and Cyanide Salts (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, Toxicological Review of Hydrogen Cyanide (HCN) and Cyanide Salts, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS As...

  13. 77 FR 69631 - Draft Guidance for IRBs, Clinical Investigators, and Sponsors: IRB Responsibilities for Reviewing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

    ...://www.fda.gov/ScienceResearch/SpecialTopics/RunningClinicalTrials/ProposedRegulationsandDraftGuidances...] Draft Guidance for IRBs, Clinical Investigators, and Sponsors: IRB Responsibilities for Reviewing the... IRBs, Clinical Investigators, and Sponsors: IRB Responsibilities for Reviewing the Qualifications of...

  14. IRIS Toxicological Review of Ammonia (Interagency Science Consultation Draft)

    EPA Science Inventory

    On June 1, 2012, the draft Toxicological Review of Ammonia and the draft charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House ...

  15. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (Interagency Science Consultation Draft)

    EPA Science Inventory

    In September 2016, EPA released the draft IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) for public comment and discussion. The draft assessment was reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent ...

  16. 77 FR 52024 - Notification of a Public Teleconference of the Chartered Science Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... Amphibole Asbestos and (2) an SAB draft report regarding EPA's Scientific and Technological Achievement... review of an SAB draft report reviewing EPA's Toxicological Review of Libby Amphibole Asbestos. The... entitled ``Toxicological Review of Libby Amphibole Asbestos.'' The EPA's draft assessment evaluates cancer...

  17. IRIS Toxicological Review of Tert-Butyl Alcohol (Tert-Butanol) (Interagency Science Consultation Draft)

    EPA Science Inventory

    On April 29, 2016, the Toxicological Review of tert-Butyl Alcohol (tert-Butanol) (Public Comment Draft) was released for public comment. The draft Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and the Executive Office ...

  18. IRIS Toxicological Review of Benzo[a]pyrene (Interagency Science Consultation Draft)

    EPA Science Inventory

    On August 21, 2013, the draft Toxicological Review of Benzo[a]pyrene and the draft charge to external peer reviewers were released for public review and comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offi...

  19. 75 FR 71694 - Science Advisory Board Staff Office; Notification of Two Public Quality Review Teleconferences of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... review of EPA's ``Toxicological Review of Trichloroethylene'' on December 15, 2010 and (b) a quality... of Trichloroethylene'' (October 2009), and (2) a draft report peer reviewing EPA's draft document... draft assessment entitled ``Toxicological Review of Trichloroethylene'' (October 2009). EPA's Office of...

  1. 75 FR 44805 - Central Utah Project Completion Act; Notice of Availability, Draft Environmental Assessment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... DEPARTMENT OF THE INTERIOR Central Utah Project Completion Act; Notice of Availability, Draft Environmental Assessment (Draft EA); Realignment of a Portion of the Utah Lake Drainage Basin Water Delivery System AGENCY: Office of the Assistant Secretary--Water and Science, Interior ACTION: Notice of...

  2. 75 FR 50761 - Draft Toxicological Review of Dichloromethane: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-17

    ... Toxicological Review of Dichloromethane: In Support of Summary Information on the Integrated Risk Information... Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R-10/003A). The draft... Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available primarily...

  3. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 1: Plenary Session

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Briefings from the plenary session of the conference on SSTAC/ARTS Review of the Draft Integrated Technology Plan (ITP) held on 24-28 Jun. 1991 are included. Viewgraphs from the presentations are included.

  4. IRIS Toxicological Review of Inorganic Arsenic (Cancer) ...

    EPA Pesticide Factsheets

    EPA's Science Advisory Board (SAB) conducted a review of the scientific basis supporting the human health cancer hazard and dose-response assessment of inorganic arsenic that will appear on the Integrated Risk Information System (IRIS) database. EPA revised the assessment and is now returning the assessment to the SAB and releasing the document to the public for a focused review of EPA's responses to the SAB recommendations. This draft IRIS health assessment addresses only cancer human health effects that may result from chronic exposure to this chemical.

  5. IRIS Toxicological Review of Ethylene Glycol Mono-Butyl ...

    EPA Pesticide Factsheets

    EPA released the draft report, Toxicological Review for Ethylene Glycol Mono-Butyl Ether , that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies and White House Offices are provided below with external peer review panel comments. EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of EGBE that will appear on the Integrated Risk Information System (IRIS) database.

  6. 76 FR 11240 - Human Studies Review Board (HSRB); Notification of a Public Teleconference To Review a Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-01

    ... subjects of research. The HSRB reports to the EPA Administrator through EPA's Science Advisor. 1. Topics...) Office of the Science Advisor (OSA) announces a public teleconference of the HSRB to discuss its draft... difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic...

  7. Report of Programme Commission II (Natural Sciences).

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). General Conference.

    As the first part of the report of the Programme Commission II, a summary of discussions on plans for natural sciences and their applications is presented in this document. The two agenda items are: (1) detailed consideration of the 1973-74 draft program and budget and of the 1973-78 draft medium-term outline, and (2) desirability of adopting an…

  8. 75 FR 33325 - Notice of Availability of the Draft Environmental Assessment of a Marine Geophysical Survey by...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ...., Menlo Park, CA 94025. Copies of the Draft EA are available in the USGS Menlo Park Earth Science Information Center, Building 3, Room 3128, 345 Middlefield Rd., Menlo Park, CA 94025, Telephone: (650) 329-4309; the USGS Anchorage Earth Science Information Center, Room 208, 4210 University Dr. Anchorage, AK...

  9. Exposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (Tcdd) and Related Compounds: Science Advisory Board (External Review Draft) (2000)

    EPA Science Inventory

    Dioxin Reassessment, SAB Review Draft

    The U.S. Environmental Protection Agency's (EPA) is progressing toward completion of its comprehensive reassessment of dioxin science entitled, "Exposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibe...

  10. EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (Volume 1) (Interagency Science Discussion Draft)

    EPA Science Inventory

    EPA is releasing the draft report, EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (Volume 1), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the 75 FR 7592 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Chartered...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-22

    ... concerning the EPA Science Advisory Board can be found on the SAB Web site at http://www.epa.gov/sab... reviews of three draft SAB Panel reports: (1) The SAB Drinking Water Committee's draft Review of EPA's... and all appropriate SAB Staff Office procedural policies. Background: (1) The SAB Drinking Water...

  11. Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide ...

    EPA Pesticide Factsheets

    On September 22, 2006, the draft Evaluation of the Carinogenicity of Ethylene Oxide (EPA/635/R-06/003) and the draft charge to external peer reviewers were released for external peer review and public comment. This draft was reviewed by EPA’s Science Advisory Board (SAB) and the expert panel’s final report was made available December 21, 2007. Since that time the Agency implemented the May 2009 IRIS assessment development process in which other federal agencies and the Executive Offices of the President are provided two opportunities to comment on IRIS human health assessments; Interagency Science Consultation (Step 3) prior to public comment/peer review and Interagency Science Discussion (Step 6b) following peer review. In July, 2011, the draft assessment incorporating the SAB recommendations (December 2007) was sent to other federal agencies and Executive Offices of the President as part of Step 6 of the IRIS process. Following the May 2009 process, all written comments submitted by other agencies will be made publicly available. Accordingly, the interagency comments for ethylene oxide and the interagency science discussion materials provided to the other agencies are posted on this site. Note: After further consideration EPA has decided to undertake an additional peer review of the revised draft assessment on how the Agency responded to the SAB panel recommendations (December 2007), the exposure-response modeling of epidemiologic data, including n

  12. EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and ...

    EPA Pesticide Factsheets

    EPA is releasing for external peer review and public comment an important draft document reviewing the literature on the health effects of dioxin and related compounds (also referred to as 2,3,7,8-Tetrachlorodibenzo-p-dioxin). At the request of Administrator Jackson, EPA is in the process of re-assessing the science on the effects of dioxin, a toxic chemical that is emitted by multiple sources, on the public’s health. This draft dioxin report is EPA’s response to key comments and recommendations made by the National Academy of Sciences on the Agency’s draft dioxin reassessment. This assessment has been in progress for many years and raises health issues of broad interest to scientists and policymakers across the federal family. The Agency’s draft report includes significant new analyses on potential cancer and non-cancer human health effects that may result from exposures to dioxins and includes an oral reference dose for what is considered to be the most toxic of the dioxin-like compounds. EPA’s Science

  13. Health Assessment Document for Diesel Exhaust (SAB Review Draft, July 2000), EPA/600/8-90/057e

    EPA Science Inventory

    This revised draft assessment of the possible health hazards from human exposure to diesel exhaust emissions updates three earlier drafts (1999, 1998 and 1994) that were reviewed by the Clean Air Scientific Advisory Committee (CASAC) of the Agency,s Science Advisory Board (SAB)....

  14. 75 FR 47595 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Clean Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ... Air Quality Standards--Second External Review Draft (June 2010). DATES: The teleconference will be... Standards--Second External Review Draft (June 2010). Background information on previous meetings and... Quality Standards--Second External Review Draft (June 2010) should be directed to Ms. Beth Hassett-Sipple...

  15. 75 FR 9206 - Science Advisory Board Staff Office; Notification of a Clean Air Scientific Advisory Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-01

    ...: Second External Review Draft and EPA's Policy Assessment for the Review of the Carbon Monoxide National Ambient Air Quality Standards: External Review Draft. The chartered CASAC will subsequently hold a public... National Ambient Air Quality Standards: Second External Review Draft and the Policy Assessment for the...

  16. Development of a Relative Potency Factor (RPF) Approach for Polycyclic Aromatic Hydrocarbon (PAH) Mixtures (Interagency Science Consultation Draft)

    EPA Science Inventory

    On February 26, 2010, the draft Development of a Relative Potency Factor (RPF) Approach for Polycyclic Aromatic Hydrocarbon (PAH) Mixtures document and the charge to external peer reviewers were released for external peer review and public comment. The draft document and t...

  17. 76 FR 80368 - Notification of Teleconferences of the Science Advisory Board Biogenic Carbon Emissions Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... Accounting Framework for Biogenic CO2 Emissions from Stationary Sources (September 2011). DATES: The... teleconferences to discuss draft responses to charge questions on EPA's draft Accounting Framework for Biogenic CO... (OAP) in EPA's Office of Air and Radiation requested SAB review of the draft report and accounting...

  18. Revision of Electro-Mechanical Drafting Program to Include CAD/D (Computer-Aided Drafting/Design). Final Report.

    ERIC Educational Resources Information Center

    Snyder, Nancy V.

    North Seattle Community College decided to integrate computer-aided design/drafting (CAD/D) into its Electro-Mechanical Drafting Program. This choice necessitated a redefinition of the program through new curriculum and course development. To initiate the project, a new industrial advisory council was formed. Major electronic and recruiting firms…

  19. 76 FR 30149 - Science Advisory Board Staff Office Notification of a Public Teleconference of the Chartered...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... of ballast water treatment systems; A Report by the EPA Science Advisory Board (May 2011 Draft... Board can be found on the EPA Web site at http://www.epa.gov/sab . SUPPLEMENTARY INFORMATION: The SAB... quality review of a draft report entitled Efficacy of ballast water treatment systems; a report by the EPA...

  1. IRIS Toxicological Review of Tetrachloroethylene ...

    EPA Pesticide Factsheets

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of tetrachloroethylene that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and appropriately in derivation of the toxicological characterization and dose-response assessments. This draft health assessment addresses both non-cancer and cancer human health effects that may result from chronic exposure to tetrachloroethylene (also called Perchloroethylene or Perc) . This is an update of an existing assessment posted on IRIS in 1988. This draft Toxicological Review includes a chronic Reference Concentration (RfC) and carcinogenicity assessment, which are not currently available on IRIS, as well as an update of the 1988 IRIS Reference Dose (RfD). Tetrachloroethylene is a chemical solvent that is widely used for dry cleaning of fabrics, metal degreasing, and in making some consumer products and other chemicals.

  2. Evaluation of the Carcinogenicity of Ethylene Oxide (2006 ...

    EPA Pesticide Factsheets

    EPA conducted a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of ethylene oxide (cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database. EPA is announcing a 30-day public comment period for this document. The release of this draft document is solely for the purpose of seeking public comment and for review by the EPA Science Advisory Board (SAB) via a meeting to be held later in 2006. The time and place of the SAB meeting will be announced in a separate Federal Register notice. This document has not been formally disseminated by EPA and does not represent, and should not be construed to represent, any Agency policy or determination. EPA will consider any public comments submitted in accordance with the requirements specified in the Notice of Public Comment Period when revising this draft document.

  3. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) (Interagency Science Consultation Draft)

    EPA Science Inventory

    On March 10, 2016, the public comment draft Toxicological Review of Hexahydro-1,3,5-trinitro-1,3,5-triazine and the draft charge to external peer reviewers were released for public review and comment. The Toxicological Review and charge were reviewed internally by EPA and by othe...

  4. IRIS Toxicological Review of n-Butanol (Interagency Science ...

    EPA Pesticide Factsheets

    On September 8, 2011, the Toxicological Review of n-Butanol (External Review Draft) was released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process, introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments with EPA's response and the interagency science consultation draft of the IRIS Toxicological Review of n-Butanol and the charge to external peer reviewers are posted on this site. EPA is undertaking an Integrated Risk Information System (IRIS) health assessment for n-butanol. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment paradigm, i.e., hazard identification and dose-response evaluation. IRIS assessments are used in combination with specific situational exposure assessment information to evaluate potential public health risk associated with environmental contaminants.

  5. IRIS Toxicological Review of Halogenated Platinum Salts and Platinum Compounds (External Review Draft)

    EPA Science Inventory

    EPA released the draft toxicological review for public comment under the Integrated Risk Information System (IRIS) Program. The original draft assessment (January 2009) has been archived but is available on this web page for the sake of transparency.

  6. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (Public Comment Draft)

    EPA Science Inventory

    In September 2016, the U.S. Environmental Protection Agency's (USEPA) released the draft Integrated Risk Information System (IRIS) Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE). Consistent with the 2013 IRIS Enhancements, draft IRIS assessments are released prior to e...

  7. Drafting. FasTrak Specialization Integrated Technical and Academic Competency (ITAC). Revised.

    ERIC Educational Resources Information Center

    Ohio State Dept. of Education, Columbus. Div. of Career-Technical and Adult Education.

    This document contains an introduction to the Ohio Integrated Technical and Academic Competency (ITAC) and Specialization ITAC; an overview of the drafting industry; a list acknowledging professionals who helped develop the competency list; and the comprehensive list of the professional or occupational competencies deemed essential for graduates…

  8. 75 FR 31433 - Science Advisory Board Staff Office; Notification of a Public Meeting of the SAB Lead Review Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... Lead Review Panel to provide a consultation on EPA's draft technical analyses that will be used to...-to-face meeting to provide a consultation on EPA's draft technical analyses that will be used to... buildings. In the future, EPA will also develop draft technical analyses to support the development of lead...

  9. 75 FR 65480 - Science Advisory Board Staff Office; Notification of Two Public Teleconferences of the Clean Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... Quality Standards for NOX and SOX: Second External Review Draft (September 2010) and a teleconference for... the Secondary National Ambient Air Quality Standards for NO X and SO X : Second External Review Draft... External Review Draft (September 2010) should be directed to Dr. Byran Hubbell, OAR, at (919) 541-0621 or...

  10. 18 CFR 5.25 - Applications requiring a draft NEPA document.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... include for comment draft license articles, a preliminary determination of the consistency of each fish...

  11. 18 CFR 5.25 - Applications requiring a draft NEPA document.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... include for comment draft license articles, a preliminary determination of the consistency of each fish...

  12. 18 CFR 5.24 - Applications not requiring a draft NEPA document.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... requiring a draft NEPA document. 5.24 Section 5.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... assessment issued pursuant to this paragraph must include draft license articles, a preliminary determination...

  13. 18 CFR 5.24 - Applications not requiring a draft NEPA document.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requiring a draft NEPA document. 5.24 Section 5.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... assessment issued pursuant to this paragraph must include draft license articles, a preliminary determination...

  14. Model Machine Shop for Drafting Instruction.

    ERIC Educational Resources Information Center

    Jackson, Carl R.

    The development and implementation of a two-year interdisciplinary course integrating a machine shop and drafting curriculum are described in the report. The purpose of the course is to provide a learning process in industrial drafting featuring identifiable orientation in skills that will enable the student to develop competencies that are…

  15. Ocean research plan reviewed

    NASA Astrophysics Data System (ADS)

    Zielinski, Sarah

    A draft plan setting out priorities for U.S. ocean research generally was lauded for its clear and well-articulated view in a recent report from a committee of the U.S. National Research Council (NRC) of the US. National Academies. However, the committee advised that the plan would benefit from a bold vision for the future of ocean science research, additional details, and a reorganization to include cross-cutting research.The draft "Charting the Course for Ocean Science in the United States: Research Priorities for the Next Decade" was made available for public comment in September 2006 by the U.S. National Science and Technology Council's Joint Subcommittee on Ocean Science and Technology.

  16. Conceptual designs and cost estimates of mechanical draft wet/dry and natural draft dry cooling systems using Curtiss-Wright integral fin-tube heat exchangers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haberski, R.J.; Bentz, J.C.

    1979-04-01

    This study was performed to establish a conceptual design and cost evaluation of an advanced technology mechanical draft wet/dry and natural draft dry cooling systems for large electric power plants using a high performance integral fin-tube heat transfer surface. This study was part of an overall DOE program to develop and demonstrate advanced concept cooling systems for large electric power plants. The results obtained show significant economic advantages compared to results previously published for conventional cooling systems. These advantages are due to the higher heat transfer and lower pressure loss which occur with the use of the selected multi-port integralmore » fin-tubes.« less

  17. 75 FR 6030 - EPA Science Advisory Board Staff Office Request for Nominations of Experts for the SAB Lead (Pb...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-05

    ... requesting public nominations of experts to form an SAB Ad Hoc Panel to review EPA's draft technical analyses... residential dust. OPPT is developing draft technical analyses that will be used to support: (a) Possible... that the SAB conduct a review of these draft technical analyses. The SAB was established by 42 U.S.C...

  18. IRIS Toxicological Review of Urea (Interagency Science ...

    EPA Pesticide Factsheets

    EPA is releasing the draft report, Toxicological Review of Urea,, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies and White House Offices are provided below with external peer review panel comments. The draft Toxicological Review of Urea provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to Urea.

  19. Science Goals of the U.S. Department of the Interior Southeast Climate Science Center

    USGS Publications Warehouse

    Dalton, Melinda S.

    2011-01-01

    In 2011, the U.S. Department of the Interior Southeast Climate Science Center (CSC) finalized the first draft of its goals for research needed to address the needs of natural and cultural partners for climate science in the Southeastern United States. The science themes described in this draft plan were established to address the information needs of ecoregion conservation partnerships, such as the Landscape Conservation Cooperatives (LCCs) and other regional conservation-science and resource-management partners. These themes were developed using priorities defined by partners and stakeholders in the Southeast and on a large-scale, multidisciplinary project-the Southeast Regional Assessment Project (SERAP)-developed in concert with those partners. Science products developed under these themes will provide models of potential future conditions, assessments of likely impacts, and tools that can be used to inform the conservation management decisions of LCCs and other partners. This information will be critical as managers try to anticipate and adapt to climate change. Resource managers in the Southeast are requesting this type of information, in many cases as a result of observed climate change effects. The Southeast CSC draft science plan identifies six science themes and frames the activities (tasks, with examples of recommended near-term work for each task included herein) related to each theme that are needed to achieve the objectives of the Southeast CSC.

  20. Leveraging Current Initiatives to Bring Earth and Space Science into Elementary and Early Childhood Classrooms: NGSS in the Context of the Classroom Technology Push

    NASA Astrophysics Data System (ADS)

    Pacheco-Guffrey, H. A.

    2016-12-01

    Classroom teachers face many challenges today such as new standards, the moving targets of high stakes tests and teacher evaluations, inconsistent/insufficient access to resources and evolving education policies. Science education in the K-5 context is even more complex. NGSS can be intimidating, especially to K-5 educators with little science background. High stakes science tests are slow to catch up with newly drafted state level science standards, leaving teachers unsure about what to change and when to implement updated standards. Amid all this change, many schools are also piloting new technology programs. Though exciting, tech initiatives can also be overwhelming to teachers who are already overburdened. A practical way to support teachers in science while remaining mindful of these stressors is to design and share resources that leverage other K-5 school initiatives. This is often done by integrating writing or math into science learning to meet Common Core requirements. This presentation will suggest a method for bringing Earth and space science learning into elementary / early childhood classrooms by utilizing the current push for tablet technology. The goal is to make science integration reasonable by linking it to technology programs that are in their early stages. The roles and uses of K-5 Earth and space science apps will be examined in this presentation. These apps will be linked to NGSS standards as well as to the science and engineering practices. To complement the app resources, two support frameworks will also be shared. They are designed to help educators consider new technologies in the context of their own classrooms and lessons. The SAMR Model (Puentadura, 2012) is a conceptual framework that helps teachers think critically about the means and purposes of integrating technology into existing lessons. A practical framework created by the author will also be shared. It is designed to help teachers identify and address the important logistical and curricular decision-making aspects of integrating technology into K-5 classroom science. This method provides clear applications for new technology while also bringing meaningful Earth and space science learning into K-5 classrooms.

  1. IRIS Public Science Meeting (June 2016)

    EPA Pesticide Factsheets

    This June 2016 public meeting is made available to solicit comments on the public comment draft of the IRIS Assessment of tert-Butanol. The draft document was re-opened in the docket for a 60-day public comment period closing on July 16, 2016.

  2. 75 FR 2154 - Central Utah Project Completion Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-14

    ..., Office of the Assistant Secretary-- Water and Science. ACTION: Notice of Availability, Draft Environmental Assessment (Draft EA), Wasatch County Water Efficiency Project Recycled Water Project. SUMMARY... of the Interior and the Central Utah Water Conservancy District are evaluating the impacts of the...

  3. The need for transparency and reproducibility in documenting values for regulatory decision making and evaluating causality: The example of formaldehyde.

    PubMed

    Van Landingham, Cynthia; Mundt, Kenneth A; Allen, Bruce C; Gentry, P Robinan

    2016-11-01

    Reproducibility and transparency in scientific reporting is paramount to advancing science and providing the foundation required for sound regulation. Recent examples demonstrate that pivotal scientific findings cannot be replicated, due to poor documentation or methodological bias, sparking debate across scientific and regulatory communities. However, there is general agreement that improvements in communicating and documenting research and risk assessment methods are needed. In the case of formaldehyde, the peer-review conducted by a National Academy of Sciences (NAS) Committee questioned the approaches used by the Integrated Risk Information System (IRIS) in developing draft unit risk values. Using the original data from the key study (Beane Freeman et al., 2009) and documentation provided in the draft IRIS profile, we attempted to duplicate the reported inhalation unit risk values and address the NAS Committee's questions regarding application of the appropriate dose-response model. Overall, documentation of the methods lacked sufficient detail to allow for replication of the unit risk estimates, specifically for Hodgkin lymphoma and leukemias, the key systemic endpoints selected by IRIS. The lack of apparent exposure-response relationships for selected endpoints raises the question whether quantitative analyses are appropriate for these endpoints, and if so, how results are to be interpreted. Copyright © 2016. Published by Elsevier Inc.

  4. IRIS Toxicological Review of Biphenyl (Interagency Science ...

    EPA Pesticide Factsheets

    On September 30, 2011, the draft Toxicological Review of Biphenyl and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process (May 2009), introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the IRIS Toxicological Review of Biphenyl and the charge to external peer reviewers are posted on this site. EPA is undertaking a new health assessment for biphenyl for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS and IRIS Summary of biohenyl that will be entered on the IRIS database. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information to evaluate potential public health risks associated with exposure assessment information to evaluate potential public health risks associated with environmental contaminants. The IRIS database is relied on for the development of risk ass

  5. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (Etbe) ...

    EPA Pesticide Factsheets

    In September 2016, EPA released the draft IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) for public comment and discussion. The draft assessment was reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science consultation materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Ethyl Tertiary Butyl Ether are posted on this site. EPA is undertaking an new health assessment for ethyl tertiary butyl ether (ETBE) for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS Summary of ETBE that will be entered on the IRIS database. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment process, i.e., hazard identification and dose-response evaluation. IRIS assessments are used nationally and internationally in combination with specific situational exposure assessment infor

  6. Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) (Version 2) (External Review Draft)

    EPA Science Inventory

    EPA announced the availability of the draft report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) for a 30-day public comment period. The ICLUS version 2 (v2) modeling tool furthered land change mod...

  7. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 5: Human Support

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Viewgraphs of briefings from the Space Systems and Technology Advisory Committee (SSTAC)/ARTS review of the draft integrated technology plan (ITP) on human support are included. Topics covered include: human support program; human factors; life support technology; fire safety; medical support technology; advanced refrigeration technology; EVA suit system; advanced PLSS technology; and ARC-EVA systems research program.

  8. 76 FR 57739 - Draft Toxicological Review of 1,4-Dioxane: In Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... Toxicological Review of 1,4-Dioxane: In Support of Summary Information on the Integrated Risk Information System... review draft human health assessment titled, ``Toxicological Review of 1,4-Dioxane: In Support of Summary... regarding the toxicity of 1,4-dioxane are now included in the 1,4-dioxane assessment. EPA is extending the...

  9. IRIS Toxicological Review of Biphenyl (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 30, 2011, the draft Toxicological Review of Biphenyl and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House...

  10. Effects of Climate Change on Aquatic Invasive Species and ...

    EPA Pesticide Factsheets

    This draft report reviews available literature on climate change effects on aquatic invasive species (AIS) and examines state level AIS management activities. This draft report assesses the state of the science of climate change effects on AIS and examines state level AIS management activities.

  11. IRIS Toxicological Review of Acrylonitrile (Interagency Science Consultation Draft)

    EPA Science Inventory

    On June 30, 2011, the draft Toxicological Review of Acrylonitrile and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House...

  12. 76 FR 50759 - National Science Board; Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ... NATIONAL SCIENCE FOUNDATION National Science Board; Sunshine Act Meeting The National Science Board's Task Force on Merit Review, pursuant to NSF regulations (45 CFR Part 614), the National Science....T. SUBJECT MATTER: Discussion of proposed revisions to the draft principles and review criteria...

  13. Earth science information: Planning for the integration and use of global change information

    NASA Technical Reports Server (NTRS)

    Lousma, Jack R.

    1992-01-01

    The Consortium for International Earth Science Information Network (CIESIN) was founded in 1989 as a non-profit corporation dedicated to facilitating access to, use and understanding of global change information worldwide. The Consortium was created to cooperate and coordinate with organizations and researchers throughout the global change community to further access the most advanced technology, the latest scientific research, and the best information available for critical environmental decision making. CIESIN study efforts are guided by Congressional mandates to 'convene key present and potential users to assess the need for investment in integration of earth science information,' to 'outline the desirable pattern of interaction with the scientific and policy community,' and to 'develop recommendations and draft plans to achieve the appropriate level of effort in the use of earth science data for research and public policy purposes.' In addition, CIESIN is tasked by NASA to develop a data center that would extend the benefits of Earth Observing System (EOS) to the users of global change information related to human dimensions issues. For FY 1991, CIESIN focused on two main objectives. The first addressed the identification of information needs of global change research and non-research user groups worldwide. The second focused on an evaluation of the most efficient mechanisms for making this information available in usable forms.

  14. The health sciences librarian in medical education: a vital pathways project task force.

    PubMed

    Schwartz, Diane G; Blobaum, Paul M; Shipman, Jean P; Markwell, Linda Garr; Marshall, Joanne Gard

    2009-10-01

    The Medical Education Task Force of the Task Force on Vital Pathways for Hospital Librarians reviewed current and future roles of health sciences librarians in medical education at the graduate and undergraduate levels and worked with national organizations to integrate library services, education, and staff into the requirements for training medical students and residents. Standards for medical education accreditation programs were studied, and a literature search was conducted on the topic of the role of the health sciences librarian in medical education. Expectations for library and information services in current standards were documented, and a draft standard prepared. A comprehensive bibliography on the role of the health sciences librarian in medical education was completed, and an analysis of the services provided by health sciences librarians was created. An essential role and responsibility of the health sciences librarian will be to provide the health care professional with the skills needed to access, manage, and use library and information resources effectively. Validation and recognition of the health sciences librarian's contributions to medical education by accrediting agencies will be critical. The opportunity lies in health sciences librarians embracing the diverse roles that can be served in this vital activity, regardless of accrediting agency mandates.

  15. IRIS TOXICOLOGICAL REVIEW OF HEXAVALENT CHROMIUM (INTERAGENCY SCIENCE CONSULTATION DRAFT)

    EPA Science Inventory

    On Septemeber 30, 2010, the draft Toxicological Review of Hexavalent Chromium and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agenc...

  16. IRIS Toxicological Review of Libby Amphibole Asbestos (Interagency Science Consultation Draft)

    EPA Science Inventory

    On August 25, 2011, the draft Toxicological Review of Libby Amphibole Asbestos and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies an...

  17. IRIS Toxicological Review of 1,4-Dioxane (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 9, 2011, the Toxicological Review of 1,4-Dioxane (with inhalation update) (External Review Draft) was posted for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House...

  18. IRIS Toxicological Review of n-Butanol (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 8, 2011, the Toxicological Review of n-Butanol (External Review Draft) was released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public re...

  19. IRIS Toxicological Review of Vanadium Pentoxide (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 30, 2011, the draft Toxicological Review of Vanadium Pentoxide and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and W...

  20. Teacher Professional Develpment That Meets 21st Century Science Education Standards

    NASA Astrophysics Data System (ADS)

    van der Veen, Wil E.; Roelofsen Moody, T.

    2011-01-01

    The National Academies are working with several other groups to develop new National Science Education Standards, with the intention that they will be adopted by all states. It is critical that the science education community uses these new standards when planning teacher professional development and understands the potential implementation challenges. As a first step in developing these new standards, the National Research Council (NRC) recently published a draft Framework for Science Education. This framework describes the major scientific ideas and practices that all students should be familiar with by the end of high school. Following recommendations from the NRC Report "Taking Science to School” (NRC, 2007), it emphasizes the importance of integrating science practices with the learning of science content. These same recommendations influenced the recently revised New Jersey Science Education Standards. Thus, the revised New Jersey standards can be valuable as a case study for curriculum developers and professional development providers. While collaborating with the New Jersey Department of Education on the development of these revised science standards, we identified two critical needs for successful implementation. First, we found that many currently used science activities must be adapted to meet the revised standards and that new activities must be developed. Second, teacher professional development is needed to model the integration of science practices with the learning of science content. With support from the National Space Grant Foundation we developed a week-long Astronomy Institute, which was presented in the summers of 2009 and 2010. We will briefly describe our professional development model and how it helped teachers to bridge the gap between the standards and their current classroom practice. We will provide examples of astronomy activities that were either adapted or developed to meet the new standards. Finally, we will briefly discuss the evaluation results.

  1. 75 FR 67149 - Request for Public Comment on the Draft 2010 National Nanotechnology Initiative Strategic Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-01

    ... Nanotechnology Initiative Strategic Plan AGENCY: White House Office of Science and Technology Policy. ACTION... Nanotechnology Initiative (NNI) Strategic Plan. The draft plan is posted at http://strategy.nano.gov . Comments... information. Overview: The National Nanotechnology Initiative (NNI) Strategic Plan is the framework that...

  2. Air Quality Criteria for Ozone and Related Photochemical Oxidants (First External Review Draft)

    EPA Science Inventory

    This first external review draft of the Air Quality Criteria for Ozone and Related Photochemical Oxidants (Ozone Criteria Document) is being released in January 2005 for public comment and for review by EPA's Clean A...

  3. 75 FR 56104 - Science Advisory Board Staff Office; Notification of Public Teleconferences of the Mountaintop...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... Public Teleconferences of the Mountaintop Mining Panel AGENCY: Environmental Protection Agency (EPA... teleconferences of the SAB Mountaintop Mining Panel to discuss the Panel's draft reports. DATES: A public... that the SAB Mountaintop Mining Panel will hold a public teleconference to discuss its draft reports...

  4. 75 FR 19971 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Clean Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... Quality Standards--First External Review Draft (March 2010). DATES: The teleconference will be held on May... assessment documents titled Particulate Matter Urban-Focused Visibility Assessment: Second External Review Draft (January 2010) and Quantitative Health Risk Assessment for Particulate Matter: Second External...

  5. 78 FR 2685 - Central Utah Project Completion Act; East Hobble Creek Restoration Project Draft Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... to fish passage, and enhancement of the existing water supply. Public Disclosure Before including... for Water and Science, Interior. ACTION: Notice of availability. SUMMARY: The draft environmental... Environmental Assessment are available for inspection at: Central Utah Water Conservancy District, 355 West...

  6. 76 FR 61100 - Notification of a Public Meeting of the Science Advisory Board Biogenic Carbon Emissions Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ... demonstrated expertise in forestry, agriculture, measurement and carbon accounting methodologies, land use... draft Accounting Framework for Biogenic CO 2 Emissions from Stationary Sources (September 2011). DATES... review EPA's draft Accounting Framework for Biogenic CO 2 Emissions from Stationary Sources (September...

  7. IRIS Toxicological Review of 1,4-Dioxane (with Inhalation Update) (Interagency Science Discussion Draft)

    EPA Science Inventory

    On September 9, 2011, the Toxicological Review of 1,4-Dioxane (inhalation) (External Review Draft) was posted for external peer review and public comment. Subsequently, the Toxicological Review and IRIS Summary were reviewed internally by EPA and by other federal agencies and Exe...

  8. 76 FR 10896 - Science Advisory Board Staff Office; Request for Nominations; CASAC Mercury Review Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... the emissions of hazardous air pollutants (HAPs) released from coal-burning electric generating units...-based standard for reducing HAP emissions. EPA is developing a draft risk assessment for mercury, entitled Technical Support Document: National- Scale Mercury Risk Assessment. This draft assessment...

  9. 78 FR 25702 - Notice of Availability of a Draft Programmatic Environmental Assessment for Fisheries Research...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-02

    ... Availability of a Draft Programmatic Environmental Assessment for Fisheries Research Conducted and Funded by... Research Conducted and Funded by the Southwest Fisheries Science Center (SWFSC).'' Publication of this... cumulative impacts of conducting and funding fisheries and ecosystem research along the U.S. West Coast...

  10. 75 FR 16106 - Draft Toxicological Review of Dichloromethane: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... science-based human health assessments to support the Agency's regulatory activities. The IRIS database... for the external review draft human health assessment titled, ``Toxicological Review of... developing human health assessments for inclusion in the IRIS database. The purpose of the listening session...

  11. 77 FR 5797 - Draft Toxicological Review of Vanadium Pentoxide: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-06

    ... Office of Research and Development. EPA is releasing this draft assessment for the purposes of public... health assessment program that evaluates quantitative and qualitative risk information on effects that..., EPA provides the highest quality science- based human health assessments to support the Agency's...

  12. Promoting Pre-college Science Education

    NASA Astrophysics Data System (ADS)

    Taylor, P. L.; Lee, R. L.

    2000-10-01

    The Fusion Education Program, with continued support from DOE, has strengthened its interactions with educators in promoting pre-college science education for students. Projects aggressively pursued this year include an on-site, college credited, laboratory-based 10-day educator workshop on plasma and fusion science; completion of `Starpower', a fusion power plant simulation on interactive CD; expansion of scientist visits to classrooms; broadened participation in an internet-based science olympiad; and enhancements to the tours of the DIII-D Facility. In the workshop, twelve teachers used bench top devices to explore basic plasma physics. Also included were radiation experiments, computer aided drafting, techniques to integrate fusion science and technology in the classroom, and visits to a University Physics lab and the San Diego Supercomputer Center. Our ``Scientist in a Classroom'' program reached more than 2200 students at 20 schools. Our `Starpower' CD allows a range of interactive learning from the effects of electric and magnetic fields on charged particles to operation of a Tokamak-based power plant. Continuing tours of the DIII-D facility were attended by more than 800 students this past year.

  13. IRIS Toxicological Review of Urea (External Review Draft) ...

    EPA Pesticide Factsheets

    EPA conducted a peer review and public comment of the scientific basis of a draft report supporting the human health hazard and dose-response assessment of Urea that when finalized will appear on the Integrated Risk Information System (IRIS) database. The draft Toxicological Review of Urea provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to Urea.

  14. ED20. Crisis or Opportunity? Earth and Space Science Education at the State and National Levels

    NASA Astrophysics Data System (ADS)

    Brett, J. M.

    2011-12-01

    Scientists and researchers, those often in oversight positions and often control of the purse strings, have historically not been kind to the Earth Systems Science (ESS) discipline. This is puzzling to those of us who are ESS educators because we know that to appreciate how our planet works it is necessary to integrate and apply all the disciplines of science. With our amazing technologies and the increasing demands of a growing population we are dramatically changing our home planet. Perhaps a crisis? As the last century ended we found ESS in the same minor league position it was in when the 20th Century started. During the review period of what was to become the National Science Education Standards (NSES) draft after draft, no matter what color the cover was, seemed to ignore, omit, or severely limit ESS topics in meteorology and oceanography. Once published the NSES became the basis for the science standards in many states with what many said were critical gaps. In the years following 1996 different groups have worked to correct the omissions they found by developing guides...Ocean Literacy: Essential Principles of Ocean Science K-12 and Climate Literacy: The Essential Principals of Climate Science. An observer on the side might have considered each effort one of lobbying to get attention, funding and materials. Each effort was clearly interested in making an impact where it mattered...in the classroom. Now our Opportunity! The NAS process for developing "A Framework for K-12 Science Education" presented ESS educators with a real opportunity and we can proudly say we made our voices heard. And while there is great enthusiasm for the framework and the Chapter 7 Earth and Space we face critically important work to bring real Earth Space Science Education into the K-12 classroom. The possibility of the standards to be developed from the Framework becoming Common Core for the majority of states following the course of ELA and mathematics requires that those who previously guarded their territory collaborate.

  15. Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide ...

    EPA Pesticide Factsheets

    In December 2016, EPA finalized its Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide. EPA’s evaluation was reviewed internally by EPA and by other federal agencies and White House Offices in October 2016, before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science discussion materials provided to other agencies, including interagency review drafts of the EPA’s Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide, are posted on this site. Note: No major science comments were received on the Interagency Science Discussion Draft. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science consultation materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Ammonia and the charge to external peer reviewers, are posted on this site.

  16. IRIS Toxicological Review of Benzo[a]pyrene (Public Comment Draft)

    EPA Science Inventory

    EPA is developing an Integrated Risk Information System (IRIS) assessment of benzo[a]pyrene and has released the draft assessment for public comment and external peer review. When final, the assessment will appear on the IRIS database.

  17. RE: Request for Correction - SAB Workgroup Review of Draft IRIS Assessment for Inorganic Arsenic

    EPA Pesticide Factsheets

    Request from Lynn Bergeson for the correction of information in the draft EPA document Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS).

  18. Connectivity of Streams and Wetlands to Downstream Waters: A Review and Synthesis of the Scientific Evidence (External Review Draft)

    EPA Science Inventory

    The Environmental Protection Agency – through the independent Scientific Advisory Board (SAB) - is soliciting public comment on a new draft science report titled: Connectivity of Streams and Wetlands to Downstream Waters. A public docket has been opened to receive com...

  19. 76 FR 36143 - Central Utah Project Completion Act: Availability of Draft Environmental Assessment; Block Notice...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... DEPARTMENT OF THE INTERIOR Central Utah Project Completion Act: Availability of Draft Environmental Assessment; Block Notice 1A, Heber Sub-Area Irrigation to M&I Water Conversion, Wasatch County, UT AGENCY: Department of the Interior, Office of the Assistant Secretary-- Water and Science. ACTION: Notice...

  20. 77 FR 47067 - Notification of Two Public Quality Review Teleconferences of the Chartered Science Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-07

    ... Assessment in Environmental Decision- Making'' (EPA-SAB-08-002). Background information about this advisory... ecological assessment action plan and (2) an SAB draft review report on EPA's accounting framework for... ``SAB Review (7-26-12 Draft) of EPA's Accounting Framework for Biogenic CO 2 Emissions from Stationary...

  1. 78 FR 68459 - Medical Device Development Tools; Draft Guidance for Industry, Tool Developers, and Food and Drug...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-14

    ... Radiological Health (CDRH) for qualification of medical device development tools (MDDT) for use in device.... Background The draft guidance describes the framework and process for the voluntary CDRH qualification of... science; and (4) more quickly and more clearly communicate with CDRH stakeholders about important advances...

  2. 77 FR 52022 - Notification of a Joint Public Teleconference of the Chartered Science Advisory Board and Board...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... Counselors (BOSC) to discuss a draft report providing advice on implementation of Office of Research and... discuss a draft report providing advice on implementation of ORD's new strategic directions for research... report. Additional information about SAB and BOSC advice on implementing ORD strategic research...

  3. 76 FR 54463 - Notification of a Joint Public Teleconference of the Chartered Science Advisory Board and Board...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... Scientific Counselors (BOSC) to discuss a draft report providing advice on Office of Research and Development... discuss a draft report providing advice on Office of Research and Development's (ORD's) new strategic... advisory report. Additional information about SAB and BOSC advice on new ORD strategic research directions...

  4. 76 FR 60825 - Draft Toxicological Review of Vanadium Pentoxide: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ...) within the EPA Office of Research and Development (ORD). EPA is releasing this draft assessment solely... quantitative and qualitative risk information on effects that may result from exposure to chemical substances found in the environment. Through the IRIS Program, EPA provides the highest quality science- based...

  5. 76 FR 17434 - Receipt of Application for an Endangered Species Act Incidental Take Permit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-29

    ... science about the delivery of wood into fish habitat. The NMFS conducted the third review through its Northwest Fisheries Science Center (Science Center) in Seattle, Washington. The Science Center review found... would be available following the provisions of the draft Lewis County HCP. Specifically, the Science...

  6. Development of the First Guideline for Professional Conduct in Medical Practice in Iran.

    PubMed

    Saeedi Tehrani, Saeedeh; Nayeri, Fatemeh; Parsapoor, Alireza; Jafarian, Ali; Labaf, Ali; Mirzazadeh, Azim; Emadi Kouchak, Hamid; Shahi, Farhad; Ghasemzadeh, Nazafarin; Asghari, Fariba

    2017-01-01

    Professional behavior is first learned at the university. One of the necessary considerations in maintaining the professional environment of the university is establishing a set of codes for the behavior of physicians and medical students. This paper describes the process of developing the professional code of conduct in Tehran University of Medical Sciences, Tehran, Iran. A review of Iranian and international literature was performed to develop the first draft of the guideline. In sessions of group discussion by the authors, the articles of the draft were evaluated for relevancy, clarity, and lack of repetition. The draft was sent for evaluation to all participants, including the medical faculty members, residents, and medical students, four times and necessary corrections were made according to the comments received. The final guideline included 76 behavior codes in 6 categories, including altruism, honor and integrity, responsibility, respect, justice, and excellence. The codes of the guideline cover the physicians' commitments in the physician-patient, physician-colleague, and instructor-student relationships in order to improve the quality of the services. The Islamic and Iranian culture were taken into consideration in developing the guideline. Accordance with the administrative and educational conditions of the universities was ensured in developing the guideline and its acceptance was ensured through extensive surveys. Thus, it is expected that this guideline will be very effective in enhancing professional commitment in medical universities.

  7. IRIS Toxicological Review of Urea (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review and public comment of the scientific basis of a draft report supporting the human health hazard and dose-response assessment of Urea that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  8. Connectivity of Streams and Wetlands to Downstream Waters ...

    EPA Pesticide Factsheets

    The Environmental Protection Agency – through the independent Scientific Advisory Board (SAB) - is soliciting public comment on a new draft science report titled: Connectivity of Streams and Wetlands to Downstream Waters. A public docket has been opened to receive comments and those comments received by November 6, 2013, will be provided to the SAB Panel for its consideration in advance of their December 16- 18, 2013 meeting. Comments received after November 6, 2013, will be marked late and cannot be guaranteed to be provided to the Panel in advance of their meeting. This draft science report presents a review and synthesis of relevant peer reviewed scientific literature that will inform an upcoming joint USEPA/ Army Corps of Engineers rulemaking to enhance protection of the chemical, physical, and biological integrity of our nation’s waters by clarifying Clean Water Act (CWA) jurisdiction. Recent decisions of the Supreme Court have underscored the need for EPA and the public to better understand the connectivity or isolation of streams and wetlands relative to larger water bodies such as rivers, lakes, estuaries, and oceans, and to use that understanding to underpin regulatory actions and increase certainty among various CWA stakeholders. This report, when finalized, will provide the scientific basis needed to clarify CWA jurisdiction, including a description of the factors that influence connectivity and the mechanisms by which connecte

  9. Draft Plan for Characterizing Commercial Data Products in Support of Earth Science Research

    NASA Technical Reports Server (NTRS)

    Ryan, Robert E.; Terrie, Greg; Berglund, Judith

    2006-01-01

    This presentation introduces a draft plan for characterizing commercial data products for Earth science research. The general approach to the commercial product verification and validation includes focused selection of a readily available commercial remote sensing products that support Earth science research. Ongoing product verification and characterization will question whether the product meets specifications and will examine its fundamental properties, potential and limitations. Validation will encourage product evaluation for specific science research and applications. Specific commercial products included in the characterization plan include high-spatial-resolution multispectral (HSMS) imagery and LIDAR data products. Future efforts in this process will include briefing NASA headquarters and modifying plans based on feedback, increased engagement with the science community and refinement of details, coordination with commercial vendors and The Joint Agency Commercial Imagery Evaluation (JACIE) for HSMS satellite acquisitions, acquiring waveform LIDAR data and performing verification and validation.

  10. IRIS Toxicological Review of Dichloromethane (Methylene ...

    EPA Pesticide Factsheets

    On March 31, 2010, the draft IRIS Toxicological Review of Dichloromethane (Methylene Chloride) external review draft document and the charge to external peer reviewers were released for public review and comment. The draft document and the charge to external peer reviewers were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process, introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the Toxicological Review of Dichloromethane (Methylene Chloride) and the charge to external peer reviewers are posted on this site. The draft Toxicological Review of Dichloromethane provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to dichloromethane.

  11. 78 FR 35940 - Content of Premarket Submissions for Management of Cybersecurity in Medical Devices; Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ...The Food and Drug Administration (FDA) is announcing the availability of the draft guidance entitled ``Content of Premarket Submissions for Management of Cybersecurity in Medical Devices.'' This guidance identifies cybersecurity issues that manufacturers should consider in preparing premarket submissions for medical devices in order to maintain information confidentiality, integrity, and availability. This draft guidance is not final nor is it in effect at this time.

  12. Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (Revised August 2014 External Review Draft) (SAB Review Draft)

    EPA Science Inventory

    EPA is seeking peer review of the scientific basis supporting the human health hazard and dose-response assessment of ethylene oxide (cancer) that will appear in the Integrated Risk Information System (IRIS) database.

  13. Openness Versus Obstruction: The Importance of Protecting Open Data and Transparency, While Guarding Against Obstruction and Interference

    NASA Astrophysics Data System (ADS)

    Rosenthal, S.; Kurtz, L.

    2017-12-01

    Open data plays an important role in facilitating scientific progress and developing sound public policies. However, sometimes important scientific initiatives can be subverted by those seeking to politicize science and attack scientists. There is a critical distinction between data openness, and forcing scientists to live in a fishbowl by demanding disclosure of traditionally confidential materials, such as peer review correspondence or preliminary drafts. The former is intended to promote scientific advances (which may well involve criticisms and disagreements), while the latter is an attempt to chill and disrupt research. Agenda-driven groups have sought to obtain scientists' private emails, preliminary drafts, and peer critiques - which may include technical jargon and "what if" debates that can easily be taken out of context - in an effort to intimidate researchers and disrupt their work. Fostering true transparency requires an understanding of what should be shared to advance scientific research, including disclosing information that might expose potential biases (such as funding information), while also protecting the candid debate, open collaboration, and academic freedom that is integral to the scientific process.

  14. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 3: Space power and thermal management

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Viewgraphs of briefings from the SSTAC/ARTS review of the draft integrated technology plan on thermal power and thermal management are presented. Topics covered include: space energy conversion research and technology; space photovoltaic energy conversion; chemical energy conversion and storage; thermal energy conversion; power management; thermal management; space nuclear power; high capacity power; surface power and thermal management; space platforms power and thermal management; and project SELENE.

  15. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 3: Space power and thermal management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Viewgraphs of briefings from the SSTAC/ARTS review of the draft integrated technology plan on thermal power and thermal management are presented. Topics covered include: space energy conversion research and technology; space photovoltaic energy conversion; chemical energy conversion and storage; thermal energy conversion; power management; thermal management; space nuclear power; high capacity power; surface power and thermal management; space platforms power and thermal management; and project SELENE.

  16. 76 FR 39103 - Science Advisory Board Staff Office Notification of a Public Teleconference of the Air Monitoring...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-05

    ... draft plans for Photochemical Assessment Monitoring Stations (PAMS) Network Re-engineering. DATES: A... information concerning the EPA CASAC can be found at the EPA CASAC Web site at http://www.epa.gov/casac . Any inquiry regarding EPA's draft plans for PAMS Network Re-engineering should be directed to Mr. Kevin...

  17. A Thesaurus for Information Technology and Education. Occasional Paper ITE/6/86.

    ERIC Educational Resources Information Center

    Lewis, R.

    Prepared for use by the Information Technology and Education (ITE) Programme of the Economic and Social Science Research Council (ESRC), this draft document is based on the 1984 EUDISED (European Documentation and Information System for Education) Thesaurus for Information Processing. This draft is a modified thesaurus which aims to keep as close…

  18. 78 FR 24693 - Draft Qualitative Risk Assessment of Risk of Activity/Food Combinations for Activities (Outside...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-26

    ... Analysis and Risk-Based Preventive Controls for Human Food'' (the proposed preventive controls rule) and... Farm.'' The purpose of the draft RA is to provide a science-based risk analysis of those activity/food... Food, Drug, and Cosmetic Act for hazard analysis and risk-based preventive controls (the proposed...

  19. Addressing Needs of Rural Health Care Providers via Distance Learning. Draft.

    ERIC Educational Resources Information Center

    Adeyemi, Gloria; And Others

    This document describes a distance learning program designed to meet the needs of rural health care providers. The program allows students to complete an Associate of Applied Science (AS) in the Meramec Physical Therapist Assistant (PTA) program through St. Louis Community College (SLCC). The first section of the document provides a draft of the…

  20. 78 FR 44117 - Notice of a Public Comment Period on the Draft IRIS Carcinogenicity Assessment for Ethylene Oxide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... Assessment (NCEA) within the EPA Office of Research and Development (ORD). The 45-day public comment period... anticipates will be undertaken by the Science Advisory Board. EPA is releasing this draft carcinogenicity... Research and Development (ORD). The public has been provided an opportunity to comment on a previous...

  1. The health sciences librarian in medical education: a vital pathways project task force

    PubMed Central

    Schwartz, Diane G.; Blobaum, Paul M.; Shipman, Jean P.; Markwell, Linda Garr; Marshall, Joanne Gard

    2009-01-01

    Objectives: The Medical Education Task Force of the Task Force on Vital Pathways for Hospital Librarians reviewed current and future roles of health sciences librarians in medical education at the graduate and undergraduate levels and worked with national organizations to integrate library services, education, and staff into the requirements for training medical students and residents. Methods: Standards for medical education accreditation programs were studied, and a literature search was conducted on the topic of the role of the health sciences librarian in medical education. Results: Expectations for library and information services in current standards were documented, and a draft standard prepared. A comprehensive bibliography on the role of the health sciences librarian in medical education was completed, and an analysis of the services provided by health sciences librarians was created. Conclusion: An essential role and responsibility of the health sciences librarian will be to provide the health care professional with the skills needed to access, manage, and use library and information resources effectively. Validation and recognition of the health sciences librarian's contributions to medical education by accrediting agencies will be critical. The opportunity lies in health sciences librarians embracing the diverse roles that can be served in this vital activity, regardless of accrediting agency mandates. PMID:19851492

  2. Earth Science: It's All about the Processes

    ERIC Educational Resources Information Center

    King, Chris

    2013-01-01

    Readers of the draft new English primary science curriculum (DfE, 2012) might be concerned to see that there is much more detail on the Earth science content than previously in the United Kingdom. In this article, Chris King, a professor of Earth Science Education at Keele University and Director of the Earth Science Education Unit (ESEU),…

  3. Integration of Cognitive Skills as a Cross-Cutting Theme Into the Undergraduate Medical Curriculum at Tehran University of Medical Sciences.

    PubMed

    Soltani, Akbar; Allaa, Maryam; Moosapour, Hamideh; Aletaha, Azadeh; Shahrtash, Farzaneh; Monajemi, Alireza; Arastoo, Tohid; Ahmadinejad, Maryam; Mirzazadeh, Azim; Khabaz Mafinejad, Mahboobeh

    2017-01-01

    Nowadays, improvement of thinking skills of students is one of the universally supported aims in the majority of medical schools. This study aims to design longitudinal theme of reasoning, problem-solving and decision-making into the undergraduate medical curriculum at Tehran University of Medical Sciences (TUMS). A participatory approach was applied to design the curriculum during 2009-2011. The project was conducted by the contribution of representatives of both basic and clinical faculty members, students and graduates at Tehran University of Medical Sciences. The first step toward integrating cognitive skills into the curriculum was to assemble a taskforce of different faculty and students, including a wide variety of fields with multidisciplinary expertise using nonprobability sampling and the snowball method. Several meetings with the contribution of experts and some medical students were held to generate the draft of expected outcomes. Subsequently, the taskforce also determined what content would fit best into each phase of the program and what teaching and assessment methods would be more appropriate for each outcome. After a pilot curriculum with a small group of second-year medical students, we implemented this program for all first-year students since 2011 at TUMS. Based on findings, the teaching of four areas, including scientific and critical thinking skills (Basic sciences), problem-solving and reasoning (Pathophysiology), evidence-based medicine (Clerkship), and clinical decision-making (Internship) were considered in the form of a longitudinal theme. The results of this study could be utilized as a useful pattern for integration of psycho-social subjects into the medical curriculum.

  4. Science, Policy, and Peer Review

    NASA Astrophysics Data System (ADS)

    Kennedy, D.

    2006-12-01

    These are intense times at the convergence between science and public policy. Because issues like climate change, stem cell research and environmental protection are being contested in choppy political water, political interests are being deployed to challenge science and researchers, and also to generate pseudo- scientific claims made in the interest of particular policy ends. In a number of cases reported in Science, administration officials have silenced their own employees, or withheld data selectively from draft reports. Added to that challenge to integrity, there is a new statutory environment that adds some complexity of its own. Beginning with the Data Quality Act, more familiarly the "Shelby Amendment," research results with significant economic impacts through regulation are now available through the Freedom of Information Act. Its successor, the Data Quality Act -- which opens a route of challenge to information released by government or gathered by others and used in advice or regulation has exposed scientists not only to having their primary data reanalyzed for the purposes of others, but to charges of research misconduct. These influences have made journal peer review more challenging in several ways, and I will outline some case examples.

  5. 78 FR 43870 - Hydrogen Energy California's Integrated Gasification Combined Cycle Project; Preliminary Staff...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... Combined Cycle Project; Preliminary Staff Assessment and Draft Environmental Impact Statement AGENCY... Combined Cycle Project Preliminary Staff Assessment/Draft Environmental Impact Statement (PSA/DEIS) (DOE... Gasification Combined Cycle Project, which would be designed, constructed, and operated by HECA, LLC. HECA's...

  6. Deadline extended for public comment on IOOS' Draft Plan for Data Management and Communications Component

    NASA Astrophysics Data System (ADS)

    The U.S. Integrated ocean Observing System (IOOS) is encouraging public comment on the draft plan for its Data Management and communications (DMAC) component. The deadline for receipt of comments has been extended to 18 November 2003.

  7. 78 FR 69462 - National Nanotechnology Initiative Strategic Plan; National Science and Technology Council...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... OFFICE OF SCIENCE AND TECHNOLOGY POLICY OFFICE National Nanotechnology Initiative Strategic Plan; National Science and Technology Council; National Nanotechnology Coordination Office AGENCY: Executive... Nanotechnology Initiative (NNI) Strategic Plan. The draft plan will be posted at www.nano.gov/2014strategy...

  8. 76 FR 7199 - Science Advisory Board Staff Office; Notification of a Public Meeting of the Science Advisory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-09

    ...The Environmental Protection Agency (EPA or Agency) Science Advisory Board (SAB) Staff Office announces a public face-to-face meeting of the SAB Panel to conduct an independent review of EPA's Draft Hydraulic Fracturing Study Plan.

  9. The Next Generation of Science Standards: Implications for Biology Education

    ERIC Educational Resources Information Center

    Bybee, Rodger W.

    2012-01-01

    The release of A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas (NRC, 2012) provides the basis for the next generation of science standards. This article first describes that foundation for the life sciences; it then presents a draft standard for natural selection and evolution. Finally, there is a…

  10. NASA Airborne Astronomy Ambassadors (AAA)

    NASA Astrophysics Data System (ADS)

    Backman, D. E.; Harman, P. K.; Clark, C.

    2016-12-01

    NASA's Airborne Astronomy Ambassadors (AAA) is a three-part professional development (PD) program for high school physics and astronomy teachers. The AAA experience consists of: (1) blended-learning professional development composed of webinars, asynchronous content learning, and a series of hands-on workshops (2) a STEM immersion experience at NASA Armstrong Flight Research Center's B703 science research aircraft facility in Palmdale, California, and (3) ongoing participation in the AAA community of practice (CoP) connecting participants with astrophysics and planetary science Subject Matter Experts (SMEs). The SETI Institute (SI) is partnering with school districts in Santa Clara and Los Angeles Counties during the AAA program's "incubation" period, calendar years 2016 through 2018. AAAs will be selected by the school districts based on criteria developed during spring 2016 focus group meetings led by the program's external evaluator, WestEd.. Teachers with 3+ years teaching experience who are assigned to teach at least 2 sections in any combination of the high school courses Physics (non-AP), Physics of the Universe (California integrated model), Astronomy, or Earth & Space Sciences are eligible. Partner districts will select at least 48 eligible applicants with SI oversight. WestEd will randomly assign selected AAAs to group A or group B. Group A will complete PD in January - June of 2017 and then participate in SOFIA science flights during fall 2017 (SOFIA Cycle 5). Group B will act as a control during the 2017-18 school year. Group B will then complete PD in January - June of 2018 and participate in SOFIA science flights in fall 2018 (Cycle 6). Under the current plan, opportunities for additional districts to seek AAA partnerships with SI will be offered in 2018 or 2019. A nominal two-week AAA curriculum component will be developed by SI for classroom delivery that will be aligned with selected California Draft Science Framework Disciplinary Core Ideas, Crosscutting Concepts, and Science and Engineering Practices. (The California Draft Framework in turn is aligned with NGSS). The AAA program will demonstrate student gains in standards-based student learning, measure changes in student attitudes towards STEM, and observe & record Ambassadors' implementation of curricular changes.

  11. NANOTECHNOLOGY WHITE PAPER | Science Inventory | US ...

    EPA Pesticide Factsheets

    Nanotechnology is the science of manipulating materials at the atomic and molecular level to develop new or enhanced materials and products. In December 2004, EPA’s Science Policy Council created a cross-Agency workgroup to identify and describe the issues EPA must address to ensure protection of human health and the environment as this new technology is developed. The draft white paper on nanotechnology is the product of the workgroup. The draft white paper describes the technology, and provides a discussion of the potential environmental benefits of nanotechnology and its applications that can foster sustainable use of resources. Risk management issues and the Agency’s statutory mandates are outlined, followed by an extensive discussion of risk assessment issues. The paper identifies research needs for both environmental applications and implications of nanotechnology and concludes with recommendations on next steps for addressing science policy issues and research needs. Supplemental information is provided in a number of appendices. The Agency will use the white paper to address research needs and risk assessment issues concerning nanotechnology. The draft white paper will undergo independent expert review, which will be conducted in the February time frame. All public comments received by January 31, 2006 will be submitted to the external review panel for their consideration. Comments received beyond that time will be considered by EPA. Follo

  12. IRIS Toxicological Review of Inorganic Arsenic (Cancer) ...

    EPA Pesticide Factsheets

    On February 19, 2010, the draft IRIS Toxicological Review of Inorganic Arsenic (Cancer) external review draft document and the charge to external peer reviewers were released for public review and comment. The draft document and the charge to external peer reviewers were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process, introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the Toxicological Review of Inorganic Arsenic and the charge to external peer reviewers are posted on this site. This draft IRIS health assessment addresses only cancer human health effects that may result from chronic exposure to this chemical. An assessment of noncancer health effects of inorganic arsenic will be released for external peer review and public comment at a later date.

  13. Drafting.

    ERIC Educational Resources Information Center

    Hughes, Larry R.

    This guide to teaching drafting, one in a series of instructional materials for junior high industrial arts education, is designed to assist teachers as they plan and implement new courses of study and as they make revisions and improvements in existing courses in order to integrate classroom learning with real-life experiences. This drafting…

  14. Integrated Computer-Aided Drafting Instruction (ICADI).

    ERIC Educational Resources Information Center

    Chen, C. Y.; McCampbell, David H.

    Until recently, computer-aided drafting and design (CAD) systems were almost exclusively operated on mainframes or minicomputers and their cost prohibited many schools from offering CAD instruction. Today, many powerful personal computers are capable of performing the high-speed calculation and analysis required by the CAD application; however,…

  15. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 6: Controls and guidance

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Viewgraphs of briefings from the Space Systems and Technology Advisory Committee (SSTAC)/ARTS review of the draft Integrated Technology Plan (ITP) on controls and guidance are included. Topics covered include: strategic avionics technology planning and bridging programs; avionics technology plan; vehicle health management; spacecraft guidance research; autonomous rendezvous and docking; autonomous landing; computational control; fiberoptic rotation sensors; precision instrument and telescope pointing; microsensors and microinstruments; micro guidance and control initiative; and earth-orbiting platforms controls-structures interaction.

  16. 75 FR 71702 - Science Advisory Board Staff Office; Request for Nominations of Experts for Review of EPA's Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... Nominations of Experts for Review of EPA's Draft Technical Report Pertaining to Uranium and Thorium In-Situ... expectation is that In-Situ Leach Recovery (ISL/ISR) operations will be the most common type of new uranium... pertaining to Uranium In-Situ Leach Recovery--Post-Closure Stability Monitoring can be found at the following...

  17. Integrated Science Assessment (ISA) for Oxides of Nitrogen ...

    EPA Pesticide Factsheets

    This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision on retaining or revising the current secondary standards for NO2, SO2, PM 2.5 and PM 10 since the prior release of the assessment. The intent of the ISA, according to the CAA, is to “accurately reflect the latest scientific knowledge expected from the presence of [a] pollutant in ambient air” (U.S. Code, 1970a, 1970b). It includes scientific research from atmospheric sciences, exposure and deposition, biogeochemistry, hydrology, soil science, marine science, plant physiology, animal physiology, and ecology conducted at multiple scales (e.g., population, community, ecosystem, landscape levels). Key information and judgments formerly found in the Air Quality Criteria Documents (AQCDs) for oxides of nitrogen, oxides of nitrogen and particulate matter for ecological effects are included; Appendixes provide additional details supporting the ISA. Together, the ISA and Appendixes serve to update and revise the last oxides of nitrogen and oxides of sulfur ISA which was published in 2008 and the ecological portion of the last particulate matter ISA, which was published in 2009.

  18. IRIS Toxicological Review of Tert-Butyl Alcohol (Tert-Butanol) (Public Comment Draft)

    EPA Science Inventory

    EPA is developing an Integrated Risk Information System (IRIS) assessment of tert-butyl Alcohol (tert-butanol) and has released the public comment draft assessment for public comment and external peer review. When final, the assessment will appear on the IRIS databa...

  19. 78 FR 40199 - Draft Spent Fuel Storage and Transportation Interim Staff Guidance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0140] Draft Spent Fuel Storage and Transportation Interim... Spent Fuel Storage and Transportation Interim Staff Guidance No. 24 (SFST-ISG-24), Revision 0, ``The Use of a Demonstration Program as Confirmation of Integrity for Continued Storage of High Burnup Fuel...

  20. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) (Public Comment Draft)

    EPA Science Inventory

    EPA is developing an Integrated Risk Information System (IRIS) assessment of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and has released the draft assessment for public comment. When final, the assessment will appear on the IRIS database.

  1. Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (Revised July 2013 External Review Draft) (Public Comment Draft)

    EPA Science Inventory

    EPA is initiating a public comment period prior to peer review of the scientific basis supporting the human health hazard and dose-response assessment of ethylene oxide (cancer) that will appear in the Integrated Risk Information System (IRIS) database.

  2. 77 FR 52025 - Notification of a Public Teleconference of the Science Advisory Board; Exposure and Human Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... Science Advisory Board; Exposure and Human Health Committee AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The Environmental Protection Agency (EPA) Science Advisory Board (SAB) Staff... draft report concerning EPA's application of computational toxicology (CompTox) data in risk assessment...

  3. 77 FR 41185 - Notification of Public Teleconferences of the Science Advisory Board Animal Feeding Operations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-12

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9699-7] Notification of Public Teleconferences of the Science...). ACTION: Notice. SUMMARY: The Environmental Protection Agency (EPA or Agency) Science Advisory Board (SAB... Panel (AFO Panel) to discuss additional EPA data and the Panel's draft advisory report regarding EPA...

  4. 75 FR 54628 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Science...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... a Public Teleconference of the Science Advisory Board; Polycyclic Aromatic Hydrocarbon (PAH... Hydrocarbon (PAH) Mixtures Review Panel to discuss its draft report on EPA's Development of a Relative Potency Factor (RPF) Approach for Polycyclic Aromatic Hydrocarbon (PAH) Mixtures. DATES: The SAB PAH Mixtures...

  5. 78 FR 53144 - Request for Nominations of Experts To Augment the Science Advisory Board Chemical Assessment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-28

    ... Science Advisory Board Chemical Assessment Advisory Committee for the Review of the EPA's Draft... Ethylene Oxide AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The EPA Science... policies. The National Center for Environmental Assessment (NCEA) in the EPA's Office of Research and...

  6. Report of the Integrated Program Planning Activity for the DOE Fusion Energy Sciences Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2000-12-01

    This report of the Integrated Program Planning Activity (IPPA) has been prepared in response to a recommendation by the Secretary of Energy Advisory Board that, ''Given the complex nature of the fusion effort, an integrated program planning process is an absolute necessity.'' We, therefore, undertook this activity in order to integrate the various elements of the program, to improve communication and performance accountability across the program, and to show the inter-connectedness and inter-dependency of the diverse parts of the national fusion energy sciences program. This report is based on the September 1999 Fusion Energy Sciences Advisory Committee's (FESAC) report ''Prioritiesmore » and Balance within the Fusion Energy Sciences Program''. In its December 5,2000, letter to the Director of the Office of Science, the FESAC has reaffirmed the validity of the September 1999 report and stated that the IPPA presents a framework and process to guide the achievement of the 5-year goals listed in the 1999 report. The National Research Council's (NRC) Fusion Assessment Committee draft final report ''An Assessment of the Department of Energy's Office of Fusion Energy Sciences Program'', reviewing the quality of the science in the program, was made available after the IPPA report had been completed. The IPPA report is, nevertheless, consistent with the recommendations in the NRC report. In addition to program goals and the related 5-year, 10-year, and 15-year objectives, this report elaborates on the scientific issues associated with each of these objectives. The report also makes clear the relationships among the various program elements, and cites these relationships as the reason why integrated program planning is essential. In particular, while focusing on the science conducted by the program, the report addresses the important balances between the science and energy goals of the program, between the MFE and IFE approaches, and between the domestic and international aspects of the program. The report also outlines a process for establishing a database for the fusion research program that will indicate how each research element fits into the overall program. This database will also include near-term milestones associated with each research element, and will facilitate assessments of the balance within the program at different levels. The Office of Fusion Energy Sciences plans to begin assembling and using the database in the Spring of 2001 as we receive proposals from our laboratories and begin to prepare our budget proposal for Fiscal Year 2003.« less

  7. 78 FR 79706 - Office of the Assistant Secretary-Water and Science; Draft Environmental Assessment of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ...The Department of the Interior (Department), the Utah Reclamation Mitigation and Conservation Commission (Mitigation Commission), and the Central Utah Water Conservancy District (CUWCD), as joint leads, are evaluating the impacts of a proposed increase in operation, maintenance and replacement activities associated with the Wasatch County Water Efficiency Project (WCWEP) and have prepared a Draft Environmental Assessment.

  8. Incorporating CAD Instruction into the Drafting Curriculum.

    ERIC Educational Resources Information Center

    Yuen, Steve Chi-Yin

    1990-01-01

    If education is to meet the challenged posed by the U.S. productivity crisis and the large number of computer-assisted design (CAD) workstations forecast as necessary in the future, schools must integrate CAD into the drafting curriculum and become aggressive in providing CAD training. Teachers need to maintain close contact with local industries…

  9. Draft Guidelines for State and Areawide Water Quality Management Program Development.

    ERIC Educational Resources Information Center

    Environmental Protection Agency, Washington, DC.

    This document discusses the draft guidelines formulated by the Environmental Protection Agency (EPA) to assist the states in establishing a management program to integrate water quality and other resource management decisions. These guidelines are pfovided so that the long range goals of the Federal Water Pollution Control Act Amendments of 1972…

  10. Surface transportation weather decision support requirements : operational concept description : advanced-integrated decision support using weather information for surface transportation decisions makers : draft version 2.0

    DOT National Transportation Integrated Search

    2000-07-14

    This is a draft document for the Surface Transportation Weather Decision Support Requirements (STWDSR) project. The STWDSR project is being conducted for the FHWAs Office of Transportation Operations (HOTO) Road Weather Management Program by Mitre...

  11. 75 FR 68333 - Notice of Availability of a Draft Programmatic Environmental Impact Statement (PEIS) for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-05

    ... YTC as well as significant but mitigable impacts to water resources at YTC. At PCMS, cumulative... assets to promote more effective training and force management. The Draft PEIS evaluates the... support integrated training with ground units. Land acquisition is not being considered as part of this...

  12. 75 FR 30395 - Stakeholder Input; National Pollutant Discharge Elimination System (NPDES) Permit Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-01

    ..., 2005 draft Peak Flows Policy. This draft Policy attempted to clarify EPA's interpretation that the... treatment plants that are recombined with the flows from the secondary treatment units prior to discharge... peak flow as part of an SSO rulemaking to allow for a holistic and integrated approach to reducing SSOs...

  13. 76 FR 18552 - Seeking Public Comment on Two Draft Chapters of the National Health Security Strategy Biennial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... Plan (BIP). This document is intended to describe the priority activities to occur during fiscal years.... The target audience for the BIP is the Nation (individuals, families, communities including all... the draft BIP document which address (1) Strategic Objective 4, Foster Integrated, Scalable Health...

  14. 76 FR 6784 - Science Advisory Board Staff Office; Notification of Two Public Teleconferences of the Science...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-08

    ... Two Public Teleconferences of the Science Advisory Board Dioxin Review Panel AGENCY: Environmental... two public teleconferences of the SAB Dioxin Review Panel to discuss its draft advisory report concerning EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments, External...

  15. 76 FR 12732 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9277-5] Science Advisory Board Staff Office; Notification of... Protection Agency (EPA). ACTION: Notice. SUMMARY: The Environmental Protection Agency (EPA or Agency) Science... inquiry regarding EPA's draft monitoring documents for NO X and SO X should be directed to Dr. Richard...

  16. 77 FR 56202 - Notification of an External Peer Review Meeting for the Draft Framework for Human Health Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... the Science Advisor announces that Versar, Inc., a contractor to the EPA, will convene an independent...: Julie Fitzpatrick, Office of the Science Advisor, Mail Code 8105-R, U.S. Environmental Protection Agency... recommendations presented in the National Research Council's report Science and Decisions: Advancing Risk...

  17. A Critical Review of the Massachusetts Next Generation Science and Technology/Engineering Standards. Policy Brief

    ERIC Educational Resources Information Center

    Metzenberg, Stan

    2015-01-01

    Stan Metzenberg offers a critical analysis of the draft "Massachusetts Science and Technology/Engineering Standards," which are for pre-Kindergarten to Grade 8 and introductory high school courses. Metzenberg claims that the document reveals significant, unacceptable gaps in science content, as well as some notable errors and…

  18. Occupationally Related Science. Draft Curriculum 1986-87.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Div. of Occupational Education Programs.

    To prepare occupational students for employment, a basic understanding of scientific knowledge and the processes of science that have been applied in the development of tools, machines, instruments, and technological techniques or processes should be taught. When a second unit of science was included for all high school students in the New York…

  19. [Common law, civil law: thinking about the tools of the judge in bioethics].

    PubMed

    Baudouin, Jean-Louis

    2006-01-01

    Civilian and common law judges differ substantially in their approach to the resolution of issues concerning bioethics and health sciences. Whereas the civilian judge will first take into account the legislative source, his common law counterpart will most probably first look at judicial precedents for guidance. In both systems, however, the legislative drafting technique differs substantially and has a direct impact on judicial interpretation of the law. Both systems also differ in the way that judicial decisions are drafted and rendered. In the common law tradition, judges draft their own opinion, leaving the possibility of dissent which, in turn, helps to better illustrate contentious issues and may have an influence on social awareness of difficult problems. Finally, in bioethics, legislation should be preferred if only for a question of social legitimacy, since decisions are then taken by elected representatives. However, this type of legislation should be subject to periodical review to better adapt its rules to the evolution of science and society.

  20. Technical Subjects. Mathematics. Science. Curriculum RP-27.

    ERIC Educational Resources Information Center

    Ontario Dept. of Education, Toronto.

    GRADES OR AGES: Grades 9-12. SUBJECT MATTER: Technical subjects and special mathematics and science courses for technical students. Technical subjects include air conditioning, auto mechanics, carpentry, drafting, applied electronics, masonry, painting, plumbing, service station operation, welding, and woodworking. ORGANIZATION AND PHYSICAL…

  1. 75 FR 4043 - Science Advisory Board; Draft Report of the NOAA Science Advisory Board Oceans and Health Working...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-26

    ...: January 20, 2010. Mark E. Brown, Chief Financial Officer, Office of Oceanic and Atmospheric Research... decide to entertain: (1) What are NOAA's unique and important scientific roles in addressing ocean health...

  2. Speculations on the Growth of Ethnobotanical Nomenclature

    ERIC Educational Resources Information Center

    Berlin, Brent

    1972-01-01

    Earlier draft of this paper prepared with the fellowship support of the Center for Advanced Study in the Behavioral Sciences and a grant from the National Science Foundation, and distributed as Working Paper No. 39, Language-Behavior Research Laboratory (March 1971). (VM)

  3. IRIS Toxicological Review of Formaldehyde (Inhalation) ...

    EPA Pesticide Factsheets

    UPDATE EPA is currently revising its Integrated Risk Information System (IRIS) assessment of formaldehyde to address the 2011 NAS peer review recommendations. This assessment addresses both noncancer and cancer human health effects that are relevant to assessing the risks from chronic inhalation exposure to formaldehyde. To facilitate discussion of several scientific issues pertinent to the assessment, EPA convened a state-of-the-science workshop on April 30 and May 1, 2014. This workshop focused on the following three themes: Evidence pertaining to the influence of formaldehyde that is produced endogenously (by the body during normal biological processes) on the toxicity of inhaled formaldehyde, and implications for the health assessment; Mechanistic evidence relevant to formaldehyde inhalation exposure and lymphohematopoietic cancers (leukemia and lymphomas); and Epidemiological research examining the potential association between formaldehyde exposure and lymphohematopoietic cancers (leukemia and lymphomas). June 2010: EPA is conducting an independent expert peer review by the National Academy of Sciences and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Formaldehyde-Inhalation that when finalized will appear on the Integrated Risk Information System (IRIS) database. This draft IRIS health assessment addresses both noncancer and cancer human health effects that may result from chronic inhal

  4. 77 FR 12836 - Draft Toxicological Review of Biphenyl: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... prepared by the National Center for Environmental Assessment (NCEA) within the EPA Office of Research and... comments and/or provide written comments at the meeting regarding the draft assessment under review. Space... the Recent Additions and Publications menus at http://www.epa.gov/ncea . A limited number of paper...

  5. 78 FR 57624 - Availability of a Draft Integrated Feasibility Report (Feasibility Study/Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ... Restoration Study, Los Angeles County, CA, for review and comment. The study evaluates alternatives for the... physical processes such as a more natural hydrologic and hydraulic regime that reconnects the river to... on November 28, 2008 (73 FR 72455). DATES: The Draft IFR is available for a 45-day review period from...

  6. 76 FR 38387 - Draft Toxicological Review of Acrylonitrile: In Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... session is to allow all interested parties to present scientific and technical comments on draft IRIS... should also submit written comments during the public comment period using the detailed and established... period begins June 30, 2011, and ends August 29, 2011. Comments should be in writing and must be received...

  7. 78 FR 26343 - Exelon Generation Company, LLC; Notice of Application Accepted for Filing, Soliciting Motions To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-06

    ... prior registration, using the eComment system at http://www.ferc.gov/docs-filing/ecomment.asp . You must... plant is integral with the dam and is composed of 13 turbine-generator units, draft tubes, and.... Water flowing through the turbines is discharged via the draft tubes into the tailrace immediately...

  8. 33 CFR Appendix A to Part 230 - Processing Corps NEPA Documents

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Appendix A to Part 230 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA Pt. 230, App. A Appendix A to Part 230—Processing... integrating the draft EIS or EA and draft FONSI (as appropriate), or a separate NEPA document and circulate it...

  9. 33 CFR Appendix A to Part 230 - Processing Corps NEPA Documents

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Appendix A to Part 230 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA Pt. 230, App. A Appendix A to Part 230—Processing... integrating the draft EIS or EA and draft FONSI (as appropriate), or a separate NEPA document and circulate it...

  10. 33 CFR Appendix A to Part 230 - Processing Corps NEPA Documents

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Appendix A to Part 230 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA Pt. 230, App. A Appendix A to Part 230—Processing... integrating the draft EIS or EA and draft FONSI (as appropriate), or a separate NEPA document and circulate it...

  11. 33 CFR Appendix A to Part 230 - Processing Corps NEPA Documents

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Appendix A to Part 230 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA Pt. 230, App. A Appendix A to Part 230—Processing... integrating the draft EIS or EA and draft FONSI (as appropriate), or a separate NEPA document and circulate it...

  12. 'Candidatus Phytoplasma phoenicium' associated with almond witches'-broom disease: from draft genome to genetic diversity among strain populations.

    PubMed

    Quaglino, Fabio; Kube, Michael; Jawhari, Maan; Abou-Jawdah, Yusuf; Siewert, Christin; Choueiri, Elia; Sobh, Hana; Casati, Paola; Tedeschi, Rosemarie; Lova, Marina Molino; Alma, Alberto; Bianco, Piero Attilio

    2015-07-30

    Almond witches'-broom (AlmWB), a devastating disease of almond, peach and nectarine in Lebanon, is associated with 'Candidatus Phytoplasma phoenicium'. In the present study, we generated a draft genome sequence of 'Ca. P. phoenicium' strain SA213, representative of phytoplasma strain populations from different host plants, and determined the genetic diversity among phytoplasma strain populations by phylogenetic analyses of 16S rRNA, groEL, tufB and inmp gene sequences. Sequence-based typing and phylogenetic analysis of the gene inmp, coding an integral membrane protein, distinguished AlmWB-associated phytoplasma strains originating from diverse host plants, whereas their 16S rRNA, tufB and groEL genes shared 100 % sequence identity. Moreover, dN/dS analysis indicated positive selection acting on inmp gene. Additionally, the analysis of 'Ca. P. phoenicium' draft genome revealed the presence of integral membrane proteins and effector-like proteins and potential candidates for interaction with hosts. One of the integral membrane proteins was predicted as BI-1, an inhibitor of apoptosis-promoting Bax factor. Bioinformatics analyses revealed the presence of putative BI-1 in draft and complete genomes of other 'Ca. Phytoplasma' species. The genetic diversity within 'Ca. P. phoenicium' strain populations in Lebanon suggested that AlmWB disease could be associated with phytoplasma strains derived from the adaptation of an original strain to diverse hosts. Moreover, the identification of a putative inhibitor of apoptosis-promoting Bax factor (BI-1) in 'Ca. P. phoenicium' draft genome and within genomes of other 'Ca. Phytoplasma' species suggested its potential role as a phytoplasma fitness-increasing factor by modification of the host-defense response.

  13. 75 FR 71701 - Science Advisory Board Staff Office; Request for Nominations of Experts for the Review of a Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... fluctuation in microbial populations. The EPA Office of the Science Advisor's Risk Assessment Forum has.... Kathryn Gallagher, Executive Director, Risk Assessment Forum, Office of the Science Advisor US EPA, Mail... person or organization may nominate qualified individuals in the areas of expertise described above for...

  14. 76 FR 10342 - Availability of Fiscal Years 2011-2016 Draft Strategic Plan and Request for Public Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... ">[email protected] hq.doe.gov . Michael Holland, Office of the Under Secretary for Science at (202) 586-0505, or e-mail [email protected]science.doe.gov . SUPPLEMENTARY INFORMATION: The DOE was established in... clear goals for DOE's four main business lines: nuclear security, environmental clean-up, science and...

  15. 78 FR 3824 - Draft Qualitative Risk Assessment of Risk of Activity/Food Combinations for Activities (Outside...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... available electronically at http://www.regulations.gov and at http://www.fda.gov/Food/ScienceResearch.... Available at: http://www.fda.gov/Food/ScienceResearch/ResearchAreas/RiskAssessmentSafetyAssessment/default...) Conducted in a Facility Co-Located on a Farm,'' 2012. Available at: http://www.fda.gov/ScienceResearch...

  16. IRIS Toxicological Review of Dichloromethane (Methylene ...

    EPA Pesticide Factsheets

    EPA is releasing the draft report, Toxicological Review of Dichloromethane, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies and White House Offices are provided below with external peer review panel comments. The draft Toxicological Review of Dichloromethane provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to dichloromethane.

  17. 75 FR 30825 - Draft Toxicological Review of Formaldehyde in Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... session is to allow all interested parties to present scientific and technical comments on draft IRIS..., they should also submit written comments at least 5 working days before the meeting date announced on... August 31, 2010. Comments should be in writing and must be received by EPA by August 31, 2010. The...

  18. 76 FR 60827 - Draft Toxicological Review of Biphenyl: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... to present scientific and technical comments on draft IRIS health assessments to EPA and other... would like EPA to share their comments with the external peer reviewers, they should also submit written..., and ends November 29, 2011. Comments should be in writing and must be received by EPA by November 29...

  19. Preliminary Steps Towards Integrating Climate and Land Use (ICLUS): the Development of Land-Use Scenarios Consistent with Climate Change Emissions Storylines (2008, External Review Draft)

    EPA Science Inventory

    This report was prepared by the Global Change Research Program (GCRP) in the National Center for Environmental Assessment (NCEA) of the Office of Research and Development (ORD) at the U.S. Environmental Protection Agency (EPA). This draft report is a description of the methods u...

  20. Integrating Clinical Practice Guidelines into Daily Practice: Impact of an Interactive Workshop on Drafting of a Written Action Plan for Asthma Patients

    ERIC Educational Resources Information Center

    Labelle, Martin; Beaulieu, Michele; Renzi, Paolo; Rahme, Elham; Thivierge, Robert L.

    2004-01-01

    Introduction: Written action plans (WAPs) are instructions that enable asthmatics to manage their condition appropriately and are recommended by current asthma clinical practice guidelines (CPGs). However, general practitioners (GPs) rarely draft WAPs for their patients. An interactive, case-based workshop for asthma, combined with an objective…

  1. USSR Report, Science and Technology Policy.

    DTIC Science & Technology

    1987-05-22

    aspect of scientific communication. It is well known that the history of science abounds in debates which are connected with factual, theoretical, and...community on the given question. The study of the forms of debate in the history of science clearly demonstrates the nature of the scientific community as...interdisciplinary research in the history of science . The plan of the State Commission for the Electrification of Russia, which was drafted in 1920 on

  2. Reflections on nursing practice science: the nature, the structure, and the foundation of nursing sciences.

    PubMed

    Orem, Dorothea E; Taylor, Susan G

    2011-01-01

    In preparation for the self-care deficit nursing theory conference to be held in Ulm, Germany in 2004, Dorothea Orem and I reflected on the development of nursing science. Orem drafted this paper which I edited. The International Orem Society is sharing this paper with Nursing Science Quarterly as presented to the conference as a memorial to Orem and her work.

  3. Earth & Space Science in the Next Generation Science Standards: Promise, Challenge, and Future Actions. (Invited)

    NASA Astrophysics Data System (ADS)

    Pyle, E. J.

    2013-12-01

    The Next Generation Science Standards (NGSS) are a step forward in ensuring that future generations of students become scientifically literate. The NGSS document builds from the National Science Education Standards (1996) and the National Assessment of Educational Progress (NAEP) science framework of 2005. Design teams for the Curriculum Framework for K-12 Science Education were to outline the essential content necessary for students' science literacy, considering the foundational knowledge and the structure of each discipline in the context of learning progressions. Once draft standards were developed, two issues emerged from their review: (a) the continual need to prune 'cherished ideas' within the content, such that only essential ideas were represented, and (b) the potential for prior conceptions of Science & Engineering Practices (SEP) and cross-cutting concepts (CCC) to limit overly constrain performance expectations. With the release of the NGSS, several challenges are emerging for geoscience education. First, the traditional emphasis of Earth science in middle school has been augmented by new standards for high school that require major syntheses of concepts. Second, the integration of SEPs into performance expectations places an increased burden on teachers and curriculum developers to organize instruction around the nature of inquiry in the geosciences. Third, work is needed to define CCCs in Earth contexts, such that the unique structure of the geosciences is best represented. To ensure that the Earth & Space Science standards are implemented through grade 12, two supporting structures must be developed. In the past, many curricular materials claimed that they adhered to the NSES, but in some cases this match was a simple word match or checklist that bore only superficial resemblance to the standards. The structure of the performance expectations is of sufficient sophistication to ensure that adherence to the standards more than a casual exercise. Claims of match must be supported not just by disciplinary core ideas, but also by SEPs and CCCs. Such a structured approach to Earth science instruction also requires specialized approaches to teacher preparation and professional development. Many teachers of Earth science are underprepared, and an examination of how Earth science teachers are prepared and supported to use to new curricular materials is also warranted. This presentation will (a) compare the structure of the NGSS and NSES for Earth & Space Science, (b) discuss the review of the NGSS drafts with respect to the intent of the Curriculum Framework, (c) provide definition to the particular challenges to instruction offered by the NGSS beyond prior instructional experience, and (d) define and reinforce concepts of what it means for curricula, instructional materials, and teacher preparation and professional development to be considered 'aligned' with the NGSS.

  4. Toward Integration: From Quantitative Biology to Mathbio-Biomath?

    PubMed Central

    de Pillis, Lisette; Findley, Ann; Joplin, Karl; Pelesko, John; Nelson, Karen; Thompson, Katerina; Usher, David; Watkins, Joseph

    2010-01-01

    In response to the call of BIO2010 for integrating quantitative skills into undergraduate biology education, 30 Howard Hughes Medical Institute (HHMI) Program Directors at the 2006 HHMI Program Directors Meeting established a consortium to investigate, implement, develop, and disseminate best practices resulting from the integration of math and biology. With the assistance of an HHMI-funded mini-grant, led by Karl Joplin of East Tennessee State University, and support in institutional HHMI grants at Emory and University of Delaware, these institutions held a series of summer institutes and workshops to document progress toward and address the challenges of implementing a more quantitative approach to undergraduate biology education. This report summarizes the results of the four summer institutes (2007–2010). The group developed four draft white papers, a wiki site, and a listserv. One major outcome of these meetings is this issue of CBE—Life Sciences Education, which resulted from proposals at our 2008 meeting and a January 2009 planning session. Many of the papers in this issue emerged from or were influenced by these meetings. PMID:20810946

  5. Trans- and Interdisciplinarity in K-14 Climate Change Education: Trends Emerging from Recent Reports by the National Research Council

    NASA Astrophysics Data System (ADS)

    Storksdieck, M.

    2012-12-01

    A recent report by the National Research Council placed climate change or climate science education deeply into the curriculum of K-12 science education in the US (A Framework for K-12 Science Education). The NRC Framework is currently being translated into the Next Generation Science Standards (NGSS), an effort by 26 states, representing 57% of the US school-aged population, under the leadership of the educational nonprofit Achieve. A first draft version of the NGSS was made available to public audiences in June of 2012, and a revised draft will be available for a second round of reviews in later November of 2012; the final version of the NGSS which will likely feature climate change and climate science as part of Earth Systems Science, but also embedded in other areas of the science curriculum, is expected to be released in the spring of 2013. It has already become apparent, though, that successful implementation of the new standards down into effective classroom-based instruction will require a deep analysis of current and likely future barriers and opportunities for engaging K-14 students in climate change education. A recently released report on an NRC workshop conducted in 2011 summarizes these discussions (Climate Change Education in Formal Settings, K-14: A Workshop Summary). The proceedings of the workshop highlight the need to think in trans- or interdisciplinary ways about educating children in primary, secondary and early post-secondary education. This report builds on a 2010 workshop that addressed how to best reach general audiences on the issue of climate change education, particularly if the desired outcome is seen as building adaptive capacity in children and adults alike. This workshop was summarized in a report entitled Climate Change Education: Goals, Audiences, and Strategies. Opportunities for engaging students in trans- or interdisciplinary exploration of climate science or climate change-related topics, while available to K-12 students, abound in undergraduate education and informal learning. This presentation will feature a variety of cases in which climate is being addressed this way, and discuss principles that one can extract from such diverse examples as an integrated undergraduate minor; a youth-oriented show and related activities for schools provided by an educational non-profit; Green Schools and other specialty initiatives at the K-12 level that integrate education around climate and energy challenges, or programs in nature and science centers that address climate issues from a stewardship perspective, addressing actions children can take as part of the educational activities themselves. Principles that have guided various successful efforts to implement trans-and interdisciplinary climate education include orientation towards local and community action; relevance to learners; commitment by leadership and staff; institutional and organizational freedom to experiment and cooperate; opportunities to explore underlying natural and social science phenomena through hands-on and active learning; and commitment to excellence and scientific "truth". The session will close with a reflection on the merits of infusing climate change throughout the learning trajectory of a child, adolescent or young adult.

  6. Tanks Focus Area Site Needs Assessment - FY 2001

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Allen, Robert W.; Josephson, Gary B.; Westsik, Joseph H.

    2001-04-30

    The TFA uses a systematic process for developing its annual program that draws from the tanks science and technology development needs expressed by the five DOE tank waste sites. TFA's annual program development process is iterative and involves the following steps: Collection of site needs; Needs analysis; Development of technical responses and initial prioritization; Refinement of the program for the next fiscal year; Formulation of the Corporate Review Budget (CRB); Preparation of Program Execution Guidance (PEG) for the next FY Revision of the Multiyear Program Plan (MYPP). This document describes the outcomes of the first phase of this process, frommore » collection of site needs to the initial prioritization of technical activities. The TFA received site needs in October - December 2000. A total of 170 site needs were received, an increase of 30 over the previous year. The needs were analyzed and integrated, where appropriate. Sixty-six distinct technical responses were drafted and prioritized. In addition, seven strategic tasks were approved to compete for available funding in FY 2002 and FY 2003. Draft technical responses were prepared and provided to the TFA Site Representatives and the TFA User Steering Group (USG) for their review and comment. These responses were discussed at a March 15, 2001, meeting where the TFA Management Team established the priority listing in preparation for input to the DOE Office of Science and Technology (OST) budget process. At the time of publication of this document, the TFA continues to finalize technical responses as directed by the TFA Management Team and clarify the intended work scopes for FY 2002 and FY 2003.« less

  7. Draft genome sequence of Lactobacillus mali KCTC 3596.

    PubMed

    Kim, Dong-Wook; Choi, Sang-Haeng; Kang, Aram; Nam, Seong-Hyeuk; Kim, Dae-Soo; Kim, Ryong Nam; Kim, Aeri; Park, Hong-Seog

    2011-09-01

    We announce the draft genome sequence of the type strain Lactobacillus mali KCTC 3596 (2,652,969 bp, with a G+C content of 36.0%), which is one of the most prevalent lactic acid bacteria present during the manufacturing process of apple juice. The genome consists of 122 large contigs (>100 bp). All of the contigs were assembled by Newbler Assembler 2.3 (454 Life Science). Copyright © 2011, American Society for Microbiology. All Rights Reserved.

  8. EPA's Science Plan for Activities Related to Dioxins in the ...

    EPA Pesticide Factsheets

    The U.S. Environmental Protection Agency is currently addressing several issues related to dioxins and dioxin-like chemicals in the environment. These include the comprehensive human health and exposure assessment for dioxin, commonly called the dioxin reassessment and a review of dioxin soil clean-up levels currently in use across the United States. To move forward with both of these efforts, as well as other dioxin related activities, a plan with interim milestones has been developed and it is outlined below. EPA’sExposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin(TCDD) and Related Compounds; Response to NAS and Completion of Dioxin Reassessment 1. EPA will release a draft report that responds to the recommendations and comments included in the National Academy of Sciences’ (NAS) 2006 review of EPA’s 2003 draft dioxin reassessment. UPDATED May 21, 2010: The draft response to comments report titled EPA’s Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (External Review Draft) (“Draft Dioxin Reanalysis”) was completed and released for public review and comment on May 21, 2010. EPA’s National Center for Environment Assessment (NCEA) in the Office of Research and Development, will prepare a limited response to key comments and recommendations in the NAS report (draft response to comments report). The draft response will focus on dose-response

  9. 77 FR 64335 - Notification of a Public Teleconference of the Science Advisory Board; Perchlorate Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... Science Advisory Board; Perchlorate Advisory Panel AGENCY: Environmental Protection Agency (EPA). ACTION... announces two public teleconferences of the SAB Perchlorate Advisory Panel to discuss its revised draft... Epidemiological Evidence to Develop a Maximum Contaminant Level Goal (MCLG) for Perchlorate. DATES: The public...

  10. 77 FR 18808 - Notification of Two Public Teleconferences of the Science Advisory Board; Libby Amphibole...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... Science Advisory Board; Libby Amphibole Asbestos Review Panel AGENCY: Environmental Protection Agency (EPA...) Staff Office announces two public teleconferences of the SAB Libby Amphibole Asbestos Panel to discuss the Panel's draft review report of EPA's Toxicological Review of Libby Amphibole Asbestos (August 2011...

  11. 76 FR 54228 - Draft Toxicological Review of Acrylonitrile: In Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... Toxicological Review of Acrylonitrile: In Support of Summary Information on the Integrated Risk Information... Acrylonitrile: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R... Acrylonitrile: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available...

  12. 78 FR 56271 - FY 2014-2020 Draft VA Strategic Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-12

    ... and access to benefits and services through integration within VA and with our partners; and... integration within VA and with our partners; and developing our workforce with the skills, tools, and... program to coordination and integration across programs and organizations, measuring performance by the...

  13. Partnering for science: proceedings of the USGS Workshop on Citizen Science

    USGS Publications Warehouse

    Hines, Megan; Benson, Abigail; Govoni, David; Masaki, Derek; Poore, Barbara; Simpson, Annie; Tessler, Steven

    2013-01-01

    What U.S. Geological Survey (USGS) programs use citizen science? How can projects be best designed while meeting policy requirements? What are the most effective volunteer recruitment methods? What data should be collected to ensure validation and how should data be stored? What standard protocols are most easily used by volunteers? Can data from multiple projects be integrated to support new research or existing science questions? To help answer these and other questions, the USGS Community of Data Integration (CDI) supported the development of the Citizen Science Working Group (CSWG) in August 2011 and funded the working group’s proposal to hold a USGS Citizen Science Workshop in fiscal year 2012. The stated goals for our workshop were: raise awareness of programs and projects in the USGS that incorporate citizen science, create a community of practice for the sharing of knowledge and experiences, provide a forum to discuss the challenges of—and opportunities for—incorporating citizen science into USGS projects, and educate and support scientists and managers whose projects may benefit from public participation in science.To meet these goals, the workshop brought together 50 attendees (see appendix A for participant details) representing the USGS, partners, and external citizen science practitioners from diverse backgrounds (including scientists, managers, project coordinators, and technical developers, for example) to discuss these topics at the Denver Federal Center in Colorado on September 11–12, 2012. Over two and a half days, attendees participated in four major plenary sessions (Citizen Science Policy and Challenges, Engaging the Public in Scientific Research, Data Collection and Management, and Technology and Tools) comprised of 25 invited presentations and followed by structured discussions for each session designed to address both prepared and ad hoc "big questions." A number of important community support and infrastructure needs were identified from the sessions and discussions, and a subteam was formed to draft a strategic vision statement to guide and prioritize future USGS efforts to support the citizen science community. Attendees also brainstormed proposal ideas for the fiscal year 2013 CDI request for proposals: one possible venue to support the execution of the vision.

  14. 75 FR 69064 - Draft Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the Integrated Risk... of Hexavalent Chromium: In Support of Summary Information on the Integrated Risk Information System... ``Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the Integrated Risk...

  15. IRIS Toxicological Review of Trichloroacetic Acid (TCA) ...

    EPA Pesticide Factsheets

    EPA is releasing the draft report, Toxicological Review of Trichloroacetic Acid (TCA), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies and White House Offices are provided below with external peer review panel comments. The draft Toxicological Review of Trichloroacetic Acid provides scientific support and rationale for the hazard identification and dose-response assessment pertaining to chronic exposure to trichloroacetic acid.

  16. Everybody wants it done but nobody wants to do it: an exploration of the barrier and enablers of critical components towards creating a clinical pathway for anxiety and depression in cancer.

    PubMed

    Rankin, Nicole M; Butow, Phyllis N; Thein, Thida; Robinson, Tracy; Shaw, Joanne M; Price, Melanie A; Clover, Kerrie; Shaw, Tim; Grimison, Peter

    2015-01-22

    This study aimed to explore barriers to and enablers for future implementation of a draft clinical pathway for anxiety and depression in cancer patients in the Australian context. Health professionals reviewed a draft clinical pathway and participated in qualitative interviews about the delivery of psychosocial care in their setting, individual components of the draft pathway, and barriers and enablers for its future implementation. Five interrelated themes were identified: ownership; resources and responsibility; education and training; patient reluctance; and integration with health services beyond oncology. The five themes were perceived as both barriers and enablers and provide a basis for an implementation plan that includes strategies to overcome barriers. The next steps are to design and deliver the clinical pathway with specific implementation strategies that address team ownership, endorsement by leaders, education and training modules designed for health professionals and patients and identify ways to integrate the pathway into existing cancer services.

  17. 76 FR 57033 - Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System..., ``Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System...-Butanol: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available...

  18. 77 FR 4584 - Sunshine Act Meetings; National Science Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-30

    ... of a National Academy of Sciences/National Research Council study CPP Task Force on Unsolicited Mid... and December 13 meeting minutes Discussion of the MS Task Force draft report CSB Task Force on Data... Task Force Closing Remarks From the Chairman Committee on Audit and Oversight (A&O) Open Session: 4-4...

  19. Interactive Learning through Web-Mediated Peer Review of Student Science Reports

    ERIC Educational Resources Information Center

    Trautmann, Nancy M.

    2009-01-01

    Two studies analyzed impacts of writing and receiving web-mediated peer reviews on revision of research reports by undergraduate science students. After conducting toxicology experiments, 77 students posted draft reports and exchanged double-blind reviews. The first study randomly assigned students to four groups representing full, partial, or no…

  20. Structural Science Laboratory Supplement. High-Technology Training Module.

    ERIC Educational Resources Information Center

    Luthens, Roger

    This module, a laboratory supplement on the theory of bending and properties of sections, is part of a first-year, postsecondary structural science technical support course for architectural drafting and design. The first part of this two-part supplement is directed at the instructor and includes the following sections: program objectives; course…

  1. Environmental Science Conference for State Supervisors of Science (Portland State University, Portland, Oregon, May 1-5, 1970).

    ERIC Educational Resources Information Center

    Portland State Univ., OR.

    The Conference report reviewed the status of man's environment and drafted guidelines for state education agencies to use for developing state programs related to environmental education. The six featured speakers and topics were: Kessler Cannon--"Report of the Governor's Committee on Natural Resources;" Dr. Harry…

  2. EPA's Report on the Environment (ROE) 2014 Draft

    EPA Science Inventory

    In the news

    EPA's Blog - It all starts with ScienceEPA's ...

  3. 76 FR 30193 - National Fish, Wildlife, and Plants Climate Adaptation Strategy; Notice of Intent: Request for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... principles and science-based practices--for reducing the negative impacts of climate change on fish, wildlife... develop a draft Strategy. The adverse impacts of climate change transcend political and administrative... climate change. This Strategy will provide a unified approach--reflecting shared principles and science...

  4. Developing young adults' representational competence through infographic-based science news reporting

    NASA Astrophysics Data System (ADS)

    Gebre, Engida H.; Polman, Joseph L.

    2016-12-01

    This study presents descriptive analysis of young adults' use of multiple representations in the context of science news reporting. Across one semester, 71 high school students, in a socioeconomically diverse suburban secondary school in Midwestern United States, participated in activities of researching science topics of their choice and producing infographic-based science news for possible online publication. An external editor reviewed their draft infographics and provided comments for subsequent revision. Students also provided peer feedback to the draft version of infographics using an online commentary tool. We analysed the nature of representations students used as well as the comments from peer and the editor feedback. Results showed both students' capabilities and challenges in learning with representations in this context. Students frequently rely on using certain kinds of representations that are depictive in nature, and supporting their progress towards using more abstract representations requires special attention and identifying learning gaps. Results also showed that students were able to determine representational adequacy in the context of providing peer feedback. The study has implication for research and instruction using infographics as expressive tools to support learning.

  5. DOD Information Technology Standard Guidance (ITSG) Version 3.1

    DTIC Science & Technology

    1997-04-07

    from NGSBs later (e.g., OSFs Motif specification became the basis for IEEE 1295 . 1). Most consortia specifications are available now, do not overlap...Illumination) CIM Center for Information Management (DISA) CINC Conumnder in Chief CIS CASE Integration Services CJCS Chairman of the Joint Chiefs of...Compound Text Encoding CUA Common User Access DAC Discretionary Access Controls DAD Draft Addendum (ISO) DAM Draft Amendment (ISO) DAP Document

  6. Progress on the HUPO Draft Human Proteome: 2017 Metrics of the Human Proteome Project.

    PubMed

    Omenn, Gilbert S; Lane, Lydie; Lundberg, Emma K; Overall, Christopher M; Deutsch, Eric W

    2017-12-01

    The Human Proteome Organization (HUPO) Human Proteome Project (HPP) continues to make progress on its two overall goals: (1) completing the protein parts list, with an annual update of the HUPO draft human proteome, and (2) making proteomics an integrated complement to genomics and transcriptomics throughout biomedical and life sciences research. neXtProt version 2017-01-23 has 17 008 confident protein identifications (Protein Existence [PE] level 1) that are compliant with the HPP Guidelines v2.1 ( https://hupo.org/Guidelines ), up from 13 664 in 2012-12 and 16 518 in 2016-04. Remaining to be found by mass spectrometry and other methods are 2579 "missing proteins" (PE2+3+4), down from 2949 in 2016. PeptideAtlas 2017-01 has 15 173 canonical proteins, accounting for nearly all of the 15 290 PE1 proteins based on MS data. These resources have extensive data on PTMs, single amino acid variants, and splice isoforms. The Human Protein Atlas v16 has 10 492 highly curated protein entries with tissue and subcellular spatial localization of proteins and transcript expression. Organ-specific popular protein lists have been generated for broad use in quantitative targeted proteomics using SRM-MS or DIA-SWATH-MS studies of biology and disease.

  7. IRIS Toxicological Review of Urea (Interagency Science ...

    EPA Pesticide Factsheets

    On September 28, 2010, the Toxicological Review of Urea and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process, introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the IRIS Toxicological Review of Urea and the charge to external peer reviewers are posted on this site. The draft Toxicological Review of Urea provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to Urea.

  8. The Fourth National Climate Assessment: Progress and Next Steps

    NASA Astrophysics Data System (ADS)

    Reidmiller, D.; Lewis, K.; Reeves, K.

    2017-12-01

    The Global Change Research Act of 1990 mandates the production of a quadrennial National Climate Assessment (NCA) that integrates, evaluates, and interprets global change science. The NCA analyzes observed and projected trends in global change and evaluates related impacts across a range of sectors and regions in the United States. The fourth assessment, NCA4, is currently under development by nearly 300 Federal and non-Federal experts and is expected to be available for public comment in Fall 2017 and released in late 2018. NCA4 is a key component of the US Global Change Research Program's Sustained Assessment process, which aims to advance the science of global change and provide authoritative, relevant information for decision makers. This talk will highlight the progress of NCA4, including an overview of the current draft of the assessment and advances since the third NCA, released in 2014. It will highlight the Climate Science Special Report, an essential component of NCA4, as well as provide insight into the public engagement process-including opportunities to participate-and identify scientific inputs and tools critical to its development, such as the 2nd State of the Carbon Cycle Report and USGCRP's new scenario products website.

  9. The integration of environmental geology methods and concepts within the framework of a regional administration; the case of the Comunidad Valenciana, Spain

    NASA Astrophysics Data System (ADS)

    Aurenheimer, C.

    The process of transfer of jurisdictions on environmental matters from the central administration to an autonomous regional government is described. The main approaches taken by different autonomous regions in Spain, to deal with the problems of setting up an environmental administrative organization are also briefly commented here. Finally, the specific structure of the environmental administration in the Comunidad Valenciana and the main guidelines of its environmental policies are explained. It is concluded that earth science can provide a very useful basis for the drafting of these policies in the region, because of the specific nature of the problems to be dealt with, related mainly to water management, soil conservation, land occupation, natural hazards and preservation of natural areas.

  10. IRIS Toxicological Review of Benzo[a]pyrene (Interagency ...

    EPA Pesticide Factsheets

    In January 2017, EPA finalized the IRIS assessment of Benzo[a]pyrene. The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science discussion materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Benzo[a]pyrene are posted on this site. EPA is undertaking an update of the Integrated Risk Information System (IRIS) health assessment for benzo[a]pyrene (BaP). The outcome of this project is an updated Toxicological Review and IRIS Summary for BaP that will be entered into the IRIS database.

  11. Integrated Model of Teacher Preparation: An Alternate Representation

    ERIC Educational Resources Information Center

    Gafoor K., Abdul

    2011-01-01

    The paper proposes an integrated model of pre-service preparation of teachers by incorporating the principles of critical and constructive approach to teacher education. The paper is an attempt to share the draft of the model with the national audience of teacher educators. The model proposed is integrated, among other things, in that in addition…

  12. 76 FR 69736 - Draft Toxicological Review of Vanadium Pentoxide: In Support of Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-09

    ... Toxicological Review of Vanadium Pentoxide: In Support of Summary Information on the Integrated Risk Information..., ``Toxicological Review of Vanadium Pentoxide: In Support of Summary Information on the Integrated Risk Information... Vanadium Pentoxide: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is...

  13. 76 FR 71029 - Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System... Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R-11/081A). On September 15, 2011, the... ``Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System...

  14. Next generation science standards available for comment

    NASA Astrophysics Data System (ADS)

    Asher, Pranoti

    2012-05-01

    The first public draft of the Next Generation Science Standards (NGSS) is now available for public comment. Feedback on the standards is sought from people who have a stake in science education, including individuals in the K-12, higher education, business, and research communities. Development of NGSS is a state-led effort to define the content and practices students need to learn from kindergarten through high school. NGSS will be based on the U.S. National Research Council's reportFramework for K-12 Science Education.

  15. Report of Programme Commission II (Natural Sciences), Annex - Recommendations.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). General Conference.

    As the second part of the report of the Programme Commission II, a summary of recommendations on plans for natural sciences and their applications is presented in this document. Resolutions and budgetary appropriations are two major concerns in the document. The topics are related to the 1973-74 draft program and budget, the 1973-78 draft…

  16. Evaluation of the East Asia and Pacific Summer Institutes Program: Final Report. Revised Draft. GS-10F-0086K

    ERIC Educational Resources Information Center

    Martinez, Alina; Neishi, Kristen; Parsad, Amanda; Whittaker, Karla; Epstein, Carter

    2012-01-01

    Students in science and engineering (S&E) are preparing for careers in fields where international partnerships are increasingly important to advancing knowledge and discoveries. It has been over a decade since the National Science Board (NSB) highlighted the importance of international collaboration and called for increased government…

  17. A Study Guide on Holography (Draft). Test Edition. AAAS Study Guides on Contemporary Problems.

    ERIC Educational Resources Information Center

    Jeong, Tung H.

    This is one of several study guides on contemporary problems produced by the American Association for the Advancement of Science with support of the National Science Foundation. The primary purpose of this guide is to provide a student with sufficient practical and technical information to begin independently practicing holography, with occasional…

  18. Ecology and Human Values: A Course of Study. (Working Draft).

    ERIC Educational Resources Information Center

    Wisconsin State Dept. of Public Instruction, Madison.

    This interdisciplinary course is designed for senior year high school students in social studies and/or science. Its main thrust is the investigation of human values as they relate to the environment, although rooted in the natural sciences as a means of understanding the complexities inherent in the environment. Use is made of the case study…

  19. CHARACTERISTICS OF THE TECHNICAL EDUCATION STUDENT.

    ERIC Educational Resources Information Center

    MILLER, AARON J.

    THE POST-HIGH SCHOOL TRAINEE SHOULD BE A HIGH SCHOOL GRADUATE OR THE EQUIVALENT. A FAIR DEGREE OF PROFICIENCY IN MATHEMATICS AND SCIENCE IS REQUIRED. IT IS REASONABLE TO EXPECT THE COMPLETION OF 2 YEARS OF HIGH SCHOOL MATHEMATICS AND 1 YEAR OF HIGH SCHOOL SCIENCE. SOME BACKGROUND IN DRAFTING AND SHOP IS DESIRABLE. THE STUDENT SHOULD BE AVERAGE OR…

  20. 75 FR 72843 - National Science Board; Sunshine Act Meetings; Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-26

    .... Electronic Distribution of Initial Chapter Drafts for Board Review. Update on Graphic Design Review of State... Education for Sustainability (SEES), Dr. Timothy Killeen. Approval of Minutes. Chairman's Report. Director's...

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Montellano, B.O. de

    This report describes later stages of a program to develop culturally relevant science and math programs for Hispanic students. Part of this effort was follow-up with 17 teachers who participated in early stages of the program. Response was not very good. Included with the report is a first draft effort for curriculum materials which could be used as is in such a teaching effort. Several of the participating teachers were invited to a writing workshop, where lesson plans were drafted, and critiqued and following rework are listed in this publication. Further work needs to be completed and is ongoing.

  2. IRIS Toxicological Review of 1,1,2,2-Tetrachloroethane ...

    EPA Pesticide Factsheets

    EPA is releasing the draft report, Toxicological Review of 1,1,2,2-Tetrachloroethane, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies and White House Offices are provided below with external peer review panel comments. The draft Toxicological Review of 1,1,2,2-Tetrachloroethane provides scientific support and rationale for the hazard and dose-response assessment pertaining to subchronic and chronic exposure to 1,1,2,2-Tetrachloroethane.

  3. Knowledge-based systems in Japan

    NASA Technical Reports Server (NTRS)

    Feigenbaum, Edward; Engelmore, Robert S.; Friedland, Peter E.; Johnson, Bruce B.; Nii, H. Penny; Schorr, Herbert; Shrobe, Howard

    1994-01-01

    This report summarizes a study of the state-of-the-art in knowledge-based systems technology in Japan, organized by the Japanese Technology Evaluation Center (JTEC) under the sponsorship of the National Science Foundation and the Advanced Research Projects Agency. The panel visited 19 Japanese sites in March 1992. Based on these site visits plus other interactions with Japanese organizations, both before and after the site visits, the panel prepared a draft final report. JTEC sent the draft to the host organizations for their review. The final report was published in May 1993.

  4. 77 FR 65364 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... Economic Impact, Governance and Regulatory Process goals, objectives and strategies initially drafted on... and threats on science and data and ecosystem based fishery management. No formal actions will be...

  5. AGU Panel meets on career topics

    NASA Astrophysics Data System (ADS)

    Hollister, Charles

    Graduate students and their career opportunities in ocean and earth sciences were the focus of the Education and Human Resources (E & HR) Committee meeting held at the 1982 AGU Fall Meeting in San Francisco. A standing committee of AGU, the E & HR committee is responsible for matters concerning education in earth, ocean, and planetary sciences from precollege through graduate programs, including career guidance, academic preparation, student recruitment, and manpower supply and demand.At the meeting a draft of the AGU-sponsored Careers in Oceanography booklet by committee chairman C. Hollister was thoroughly discussed and a new draft will emerge soon for final approval. The booklet is designed to complement the Careers in Geophysics booklet recently published by AGU; the booklets contain information about planning a career, job opportunities, educational requirements, and a synopsis of where the prospective student might apply.

  6. Computer-Integrated Manufacturing Technology. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Lakeland Tech Prep Consortium, Kirtland, OH.

    This tech prep competency profile for computer-integrated manufacturing technology begins with definitions for four occupations: manufacturing technician, quality technician, mechanical engineering technician, and computer-assisted design/drafting (CADD) technician. A chart lists competencies by unit and indicates whether entire or partial unit is…

  7. 76 FR 31507 - Domestic Licensing of Source Material-Amendments/Integrated Safety Analysis

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-01

    ... Licensing of Source Material--Amendments/Integrated Safety Analysis AGENCY: Nuclear Regulatory Commission... rule announced the availability of a draft regulatory analysis for public comment. This document... in Section XI, ``Regulatory Analysis.'' The correct ADAMS accession number is ML102380243. DATES: The...

  8. Career Profiles- Drawing Controller Kelvin Siu- Operations Engineering Branch

    NASA Image and Video Library

    2016-06-23

    The Drawing Control group provides project support in the form of drafting services, drawing version management, and drawing archival. The office provides drafting services through creation of new drawings and sketches, or integration of red-lines. They maintain physical and electronic storage of flight vehicle drawings, and archive all sketches for the AFRC community. This office is the controlling organization for all Armstrong drawing formats and maintains the drawing numbering system for flight vehicle projects.

  9. Geological science needs studied

    NASA Astrophysics Data System (ADS)

    The Geological Sciences Board of the National Academy of Science is conducting a study of the trends, needs, and priorities of the geological sciences for the 1980s. Many organizations and individuals already have been contacted regarding this task; however, in order to ensure that the forthcoming report is based broadly on ideas from the scientific community, the Geological Sciences Board solicits the thoughts of AGU members about the substance of the study. Please send your questions and comments by early this fall to William Dickinson, chairman of the Geological Sciences Board, National Academy of Sciences, Room 69, 2101 Constitution Ave., N.W., Washington, D.C. 20418. A draft report is expected in January 1983.

  10. Course Goals in Social Science, Grades K-12. Critique Draft.

    ERIC Educational Resources Information Center

    Multnomah County Intermediate Education District, Portland, OR.

    This document on course goals in the social sciences is one part of a critique series dealing with the development and evaluation of course goals in six subject matter areas for grades K-12. The series provides an initial pool of course-level goals that are expected to be of considerable value in assisting educators with goal definition related to…

  11. Maryland State Department of Education: Analysis of the Voluntary State Curriculum (VSC) in Science Grades Pre-K-8

    ERIC Educational Resources Information Center

    Achieve, Inc., 2005

    2005-01-01

    In response to a proposal request from the state, Achieve reviewed the draft of Maryland's Pre-K-8 Voluntary State Curriculum (VSC) in Science (dated May 2004). This preliminary report summarizes their findings and also reflects the discussion that followed their presentation to representatives of the Maryland State Department of Education on…

  12. 75 FR 33615 - Draft EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (EPA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-14

    ... the IRIS Program, EPA provides the highest quality science-based human health assessments to support... comments included in the National Academy of Sciences (NAS) 2006 report. In addition, it includes new analyses on potential human effects that may result from exposure to 2,3,7,8- tetrachlorodibenzo-p-dioxin...

  13. 78 FR 72873 - Availability of 2014-2018 Draft Strategic Plan and Request for Public Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... energy, environmental, and nuclear security of the United States; promoting scientific and technological innovation in support of that mission; sponsoring basic research in the physical sciences; [[Page 72874

  14. Relocating anti-racist science: the 1950 UNESCO Statement on Race and economic development in the global South.

    PubMed

    Gil-Riaño, Sebastián

    2018-06-01

    This essay revisits the drafting of the first UNESCO Statement on Race (1950) in order to reorient historical understandings of mid-twentieth-century anti-racism and science. Historians of science have primarily interpreted the UNESCO statements as an oppositional project led by anti-racist scientists from the North Atlantic and concerned with dismantling racial typologies, replacing them with population-based conceptions of human variation. Instead of focusing on what anti-racist scientists opposed, this article highlights the futures they imagined and the applied social-science projects that anti-racist science drew from and facilitated. The scientific experts who participated in drafting the first UNESCO Statement on Race played important roles in late colonial, post-colonial and international projects designed to modernize, assimilate and improve so-called backward communities - typically indigenous or Afro-descendent groups in the global South. Such connections between anti-racist science and the developmental imaginaries of the late colonial period indicate that the transition from fixed racial typologies to sociocultural and psychological conceptualizations of human diversity legitimated the flourishing of modernization discourses in the Cold War era. In this transition to an economic-development paradigm, 'race' did not vanish so much as fragment into a series of finely tuned and ostensibly anti-racist conceptions that offered a moral incentive for scientific elites to intervene in the ways of life of those deemed primitive.

  15. Surface transportation weather decision support requirements : advanced-integrated decision support using weather information for surface transportation decisions makers : draft (truncated*) version 1.0

    DOT National Transportation Integrated Search

    1997-09-19

    This report gives an overview of the National Intelligent Transportation Infrastructure Initiative (NITI). NITI refers to the integrated electronics, communications, and hardware and software elements that are available to support Intelligent Transpo...

  16. IRIS Toxicological Review of Tetrahydrofuran (THF) ...

    EPA Pesticide Factsheets

    EPA is releasing the draft report, Toxicological Review of Tetrahydrofuran, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies and White House Offices are provided below with external peer review panel comments. EPA is undertaking an Integrated Risk Information System (IRIS) health assessment for tetrahydrofuran. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment paradigm, i.e., hazard identification and dose-response evaluation. IRIS assessments are used in combination with specific situational exposure assessment information to evaluate potential public health risk associated with environmental contaminants.

  17. The Evolving Florida Science Standards for K-12 Geocience - An Overview, Journey, Trials, and Tribulations

    NASA Astrophysics Data System (ADS)

    Ruscher, P. H.

    2008-05-01

    Introduction This paper will discuss the process that went into the development of new teacher standards for Florida's K-12 science benchmarks over 2007-2008. Florida developed its first set of science standards at about the same time that the National Science Education Standards debuted, in the mid-1990s, and the two documents produced had little in common with other, particularly with regard to controversial issue of evolution, and was also quite weak in the treatment of earth/space (or geoscience) content expectations. The process created panels of Framers and Writers (with much overlap) and led to the creation of a draft set of documents in the fall of 2007 after much electronic and face-to-face collaboration at several meetings. The public was then invited to comment on the draft, and the comments came fast and furious (some really were, in fact, furious). But most were highly complementary, and external professional reviewers lauded the changes from Florida's existing "mile-wide, inch-deep" standards to a much more reasonable core group of standards. Over a 60-day period, over 20,000 individual comments were submitted, and over 100,000 numerical ratings (on a 5 point scale) were entered. In January 2008, these comments were reviewed and that culminated in a final draft of the standards, presented to the State Department of Education and its Commissioner, in late January. The process became fraught with political pressures late, however, as anti-evolutionists led an assault on some aspects of the Life Sciences standards, which had repercussions in particular related to fossil evidence in the Earth/Space Science standards, The talk will summarize the process of evolution that this forced the standards to undergo. Nature of Science There is an expanded section of Nature of Science benchmarks and standards that are based on over twenty years of research in science education that cut across all standard areas (life, physical, and earth/space). This body of knowledge exists at all levels from kindergarten to 12th grade, and serves to assure that science is inquiry-based, if not directly experientially-based, encourages laboratory and field work in science, and serves to elevate science teaching. Impacts on the Florida Science FCAT (Florida Comprehensive Assessment Test) will also be discussed. Geoscience Components Our efforts concentrated on all aspects of Earth/Space Science, including astronomy, cosmology, hydrology, geology, climatology, meteorology, and oceanography (and various other sub-disciplines one could name). We include societal impacts such as the impact of the space program on Florida, disaster mitigation and preparation, and resource utilization. Linkages to physical and life sciences are explicit, allowing for the creation of new crosscutting curricula that might provide interesting new challenges for implementers at the district (e.g., county) level.

  18. Yucca Mountain nuclear waste repository prompts heated congressional hearing

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-11-01

    Although the final report of the Blue Ribbon Commission on America's Nuclear Future is not expected until January 2012, the tentative conclusions of the commission's draft report were dissected during a recent joint hearing by two subcommittees of the House of Representatives' Committee on Science, Space, and Technology. Among the more heated issues debated at the hearing was the fate of the stalled Yucca Mountain nuclear waste repository in Nevada. The Blue Ribbon Commission's (BRC) draft report includes recommendations for managing nuclear waste and for developing one or more permanent deep geological repositories and interim storage facilities, but the report does not address the future of Yucca Mountain. The BRC charter indicates that the commission is to "conduct a comprehensive review of policies for managing the back end of the nuclear fuel cycle." However, the draft report states that the commission was not asked to consider, and therefore did not address, several key issues. "We have not rendered an opinion on the suitability of the Yucca Mountain site or on the request to withdraw the license application for Yucca Mountain," the draft report states.

  19. 75 FR 28074 - Advisory Committee on Reactor Safeguards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ..., 2009, (74 FR 52829-52830). Wednesday, June 9, 2010, Conference Room T2-B1, Two White Flint North... Regulatory Guide (RG) 1.216, ``Containment Structural Integrity Evaluation for Internal Pressure Loadings... representatives of the NRC staff regarding draft final RG 1.216, ``Containment Structural Integrity Evaluation for...

  20. RE: Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System -- Comments Submitted for Review by the SAB Workgroup

    EPA Pesticide Factsheets

    Submission of comments by the Organic Arsenical Products Task Force on the draft document Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS).

  1. Dan Goldin Presentation: Pathway to the Future

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the "Path to the Future" presentation held at NASA's Langley Center on March 31, 1999, NASA's Administrator Daniel S. Goldin outlined the future direction and strategies of NASA in relation to the general space exploration enterprise. NASA's Vision, Future System Characteristics, Evolutions of Engineering, and Revolutionary Changes are the four main topics of the presentation. In part one, the Administrator talks in detail about NASA's vision in relation to the NASA Strategic Activities that are Space Science, Earth Science, Human Exploration, and Aeronautics & Space Transportation. Topics discussed in this section include: space science for the 21st century, flying in mars atmosphere (mars plane), exploring new worlds, interplanetary internets, earth observation and measurements, distributed information-system-in-the-sky, science enabling understanding and application, space station, microgravity, science and exploration strategies, human mars mission, advance space transportation program, general aviation revitalization, and reusable launch vehicles. In part two, he briefly talks about the future system characteristics. He discusses major system characteristics like resiliencey, self-sufficiency, high distribution, ultra-efficiency, and autonomy and the necessity to overcome any distance, time, and extreme environment barriers. Part three of Mr. Goldin's talk deals with engineering evolution, mainly evolution in the Computer Aided Design (CAD)/Computer Aided Engineering (CAE) systems. These systems include computer aided drafting, computerized solid models, virtual product development (VPD) systems, networked VPD systems, and knowledge enriched networked VPD systems. In part four, the last part, the Administrator talks about the need for revolutionary changes in communication and networking areas of a system. According to the administrator, the four major areas that need cultural changes in the creativity process are human-centered computing, an infrastructure for distributed collaboration, rapid synthesis and simulation tools, and life-cycle integration and validation. Mr. Goldin concludes his presentation with the following maxim "Collaborate, Integrate, Innovate or Stagnate and Evaporate." He also answers some questions after the presentation.

  2. 75 FR 32763 - Science Advisory Board Staff Office; Notification of a Public Meeting of the Clean Air Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ...The Environmental Protection Agency (EPA) Science Advisory Board (SAB) Staff Office announces a public meeting on July 26-27, 2010 of the Clean Air Scientific Advisory Particulate Matter Review Panel (Panel) to review EPA's forthcoming Policy Assessment for the Review of Particulate Matter National Ambient Air Quality Standards-- Second External Review Draft (June 2010).

  3. Reading, readability, and legibility research: implications for notification letters.

    PubMed

    Zimmerman, D E

    1993-01-01

    This article defines communication science and then briefly describes three research areas relevant to worker notifications: (1) receiving of notification messages, (2) reading and understanding of notification messages, and (3) influences or effects of notification messages on workers. Next, the article focuses on the reading and legibility research relevant to worker notifications and then provides 16 guidelines for drafting worker notifications. Finally, the article suggests evaluating draft notifications by using one or more of the following: skilled editorial reviews, readability scoring, Cloze techniques, signal stopping techniques, in-depth personal interviews, focus groups, and usability testing.

  4. Draft genome sequence of Dethiobacter alkaliphilus strain AHT1T, a gram-positive sulfidogenic polyextremophile

    DOE PAGES

    Melton, Emily Denise; Sorokin, Dimitry Y.; Overmars, Lex; ...

    2017-09-21

    Dethiobacter alkaliphilus strain AHT1 T is an anaerobic, sulfidogenic, moderately salt-tolerant alkaliphilic chemolithotroph isolated from hypersaline soda lake sediments in northeastern Mongolia. It is thus a Gram-positive bacterium with low GC content, within the phylum Firmicutes. We report its draft genome sequence, which consists of 34 contigs with a total sequence length of 3.12 Mbp. D. alkaliphilus strain AHT1 T was sequenced by the Joint Genome Institute (JGI) as part of the Community Science Program due to its relevance to bioremediation and biotechnological applications.

  5. Draft genome sequence of Dethiobacter alkaliphilus strain AHT1T, a gram-positive sulfidogenic polyextremophile

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Melton, Emily Denise; Sorokin, Dimitry Y.; Overmars, Lex

    Dethiobacter alkaliphilus strain AHT1 T is an anaerobic, sulfidogenic, moderately salt-tolerant alkaliphilic chemolithotroph isolated from hypersaline soda lake sediments in northeastern Mongolia. It is thus a Gram-positive bacterium with low GC content, within the phylum Firmicutes. We report its draft genome sequence, which consists of 34 contigs with a total sequence length of 3.12 Mbp. D. alkaliphilus strain AHT1 T was sequenced by the Joint Genome Institute (JGI) as part of the Community Science Program due to its relevance to bioremediation and biotechnological applications.

  6. IRIS Toxicological Review of Libby Amphibole Asbestos ...

    EPA Pesticide Factsheets

    On August 25, 2011, the draft Toxicological Review of Libby Amphibole Asbestos and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process (May 2009), introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the IRIS Toxicological Review of Libby Amphibole Asbestos and the charge to external peer reviewers are posted on this site. The project supports OSWER and Region 8 site clean-up and related risk management initiatives at this Superfund site. As with all IRIS assessments, the draft document will undergo agency review, OMB/interagency review and independent external peer review before being included on the IRIS data base.

  7. IRIS Toxicological Review of 1,4-Dioxane (with Inhalation ...

    EPA Pesticide Factsheets

    On September 9, 2011, the Toxicological Review of 1,4-Dioxane (inhalation) (External Review Draft) was posted for external peer review and public comment. Subsequently, the Toxicological Review and IRIS Summary were reviewed internally by EPA and by other federal agencies and Executive Office of the President before final public release. Based on the 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and the Executive Office of the President will be made publicly available. Accordingly, interagency comments with EPA's response and the interagency science discussion draft of the IRIS Toxicological Review of 1,4-dioxane (with inhalation update) and the draft IRIS Summary are posted on this site. The Toxicological Review of 1,4-dioxane provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to 1,4-dioxane.

  8. FRAMEWORK FOR CUMULATIVE RISK ASSESSMENT (EXTERNAL REVIEW DRAFT)

    EPA Science Inventory

    Several reports have highlighted the importance of understanding the accumulation of risks from multiple environmental stressors. These include the National Research Councils 1994 report Science and Judgment in Risk Assessment and the 1997 report by the Presidential/Congressional...

  9. FRAMEWORK FOR CUMULATIVE RISK ASSESSMENT (REVIEW DRAFT)

    EPA Science Inventory

    Several reports have highlighted the importance of understanding the accumulation of risks from multiple environmental stressors. These include the National Research Council's 1994 report Science and Judgment in Risk Assessment and the 1997 report by the Presidential/Cong...

  10. Implementation Options For the Solar System Exploration Survey's "Jupiter Polar Orbiter with Probes" Mission

    NASA Astrophysics Data System (ADS)

    Spilker, T. R.

    2002-09-01

    In July of this year the National Academy of Science released a draft of its report, "New Frontiers in the Solar System: An Integrated Exploration Strategy," briefly describing the current state of solar system planetary science and the most important science objectives for the next decade (2003-2013). It includes a prioritized list of five mission concepts that might be flown as part of NASA's fledgling New Frontiers Program; each "concept" is more a list of science or measurement objectives than a full mission concept, since it does not specify implementation details in most cases. Number three on that list is the "Jupiter Polar Orbiter with Probes" ("JPOP") mission. This mission concept combines the strengths of previously described or proposed Jupiter missions into a single mission, and gains from the synergies of some of the newly-combined investigations. The primary science objectives are: 1. Determine if Jupiter has a central core 2. Determine the deep abundance of water (and other volatiles) 3. Measure Jupiter's deep winds 4. Determine the structure of Jupiter's dynamo magnetic field 5. Sample in situ Jupiter's polar magnetosphere This paper examines some of the implementation options for a JPOP mission, and gives relative advantages and disadvantages. Given the New Frontier Program's maximum cost to NASA of \\650M, plus an approx. \\120M cap on international contributions, implementing the full range of JPOP science objectives in a single New Frontiers mission may be challenging. This work was performed at the Jet Propulsion Laboratory / California Institute of Technology, under contract with the National Aeronautics and Space Administration.

  11. I-880 Integrated Corridor Management Concept of Operation : Final Submittal: Concept of Operations for the I-880 Corridor in Oakland, California

    DOT National Transportation Integrated Search

    2008-03-31

    This report describes the draft Concept of Operations that has been developed for the Integrated Corridor Mobility (ICM) program by the I-880 corridor team. The I-880 corridor team has defined this Concept of Operations (ConOps) based on two primary ...

  12. Rapid rise predicted for geologist salaries

    NASA Astrophysics Data System (ADS)

    The number of geologists entering the earth science profession and their average salary will increase faster than for other natural and physical sciences during the next 2 decades, according to A.G. Unklesbay, executive director of the American Geological Institute (AGI). He is drafting for the National Academy of Sciences' Geological Sciences Board (Eos, 62, p. 107, March 17) a chapter on manpower needs in geology.‘AGI studies trends in geoscience education, and our records show that majors have doubled in the decade 1971-1980,’ Unklesbay said. ‘These studies are ongoing and the data for 1981 show this trend continuing.’

  13. Guidelines for Preparing Economic Analysis (2010, revised 2014)

    EPA Pesticide Factsheets

    The Guidelines for Preparing Economic Analyses: External Review Draft have been prepared for review by the EPA Science Advisory Board and are part of a continuing effort by the U.S. EPA to develop improved economic guidance to support decision making.

  14. 78 FR 15012 - Request for Nominations of Experts for a Science Advisory Board Panel To Review EPA's Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-08

    ... expertise in stream ecology or wetland ecology, particularly with respect to freshwater stream-wetland... address http://yosemite.epa.gov/sab/sabproduct.nsf/Web/ethics?OpenDocument . The approved policy under...

  15. Earth Science Literacy: Building Community Consensus

    NASA Astrophysics Data System (ADS)

    Wysession, M.; Ladue, N.; Budd, D.; Campbell, K.; Conklin, M.; Lewis, G.; Raynolds, R.; Ridky, R.; Ross, R.; Taber, J.; Tewksbury, B.; Tuddenham, P.

    2008-12-01

    During 2008, the Earth Sciences Literacy Initiative (ESLI) constructed a framework of earth science "Big Ideas" and "Supporting Concepts". Following the examples of recent literacy efforts in the ocean, atmosphere and climate research communities, ESLI has distilled the fundamental understandings of the earth science community into a document that all members of the community will be able to refer to when working with educators, policy-makers, the press and members of the general public. This document is currently in draft form for review and will be published for public distribution in 2009. ESLI began with the construction of an organizing committee of a dozen people who represent a wide array of earth science backgrounds. This group then organized and ran two workshops in 2008: a 2-week online content workshop and a 3-day intensive writing workshop. For both workshops, participants were chosen so as to cover the full breadth of earth science related to the solid earth, surficial processes, and fresh-water hydrology. The asynchronous online workshop included 350 scientists and educators participating from around the world and was a powerful way to gather ideas and information while retaining a written record of all interactions. The writing workshop included 35 scientists, educators and agency representatives to codify the extensive input of the online workshop. Since September, 2008, drafts of the ESLI literacy framework have been circulated through many different channels to make sure that the document accurately reflects the current understandings of earth scientists and to ensure that it is widely accepted and adopted by the earth science communities.

  16. SEARCH: Study of Environmental Arctic Change—A System-scale, Cross-disciplinary Arctic Research Program

    NASA Astrophysics Data System (ADS)

    Wiggins, H. V.; Eicken, H.; Fox, S. E.

    2012-12-01

    SEARCH is an interdisciplinary and interagency program that works with academic and government agency scientists to plan, conduct, and synthesize studies of arctic change. The vision of SEARCH is to provide scientific understanding of arctic environmental change to help society understand and respond to a rapidly changing Arctic. Towards this end, SEARCH: 1. Generates and synthesizes research findings and promotes arctic science and scientific discovery across disciplines and among agencies. 2. Identifies emerging issues in arctic environmental change. 3. Provides information resources to arctic stakeholders, policy-makers, and the public to help them respond to arctic environmental change. 4. Coordinates with national arctic science programs integral to SEARCH goals. 5. Facilitates research activities across local-to-global scales with stakeholder concerns incorporated from the start of the planning process. 6. Represents the U.S. arctic environmental change science community in international and global change research initiatives. Specific current activities include: Arctic Observing Network (AON) - coordinating a system of atmospheric, land- and ocean-based environmental monitoring capabilities that will significantly advance our observations of arctic environmental conditions. Arctic Sea Ice Outlook ¬- an international effort that provides monthly summer reports synthesizing community estimates of the expected sea ice minimum. Sea Ice for Walrus Outlook - a resource for Alaska Native subsistence hunters, coastal communities, and others that provides weekly reports with information on sea ice conditions relevant to walrus in Alaska waters. In April, the SEARCH Science Steering Committee (SSC) released a set of draft 5-year goals and objectives for review by the broader arctic science community. The goals and objectives will direct the SEARCH program in the next five years. The draft SEARCH goals focus on four areas: ice-diminished Arctic Ocean, warming permafrost, land ice and sea level, and societal and policy implications. Together, the goals will provide significant insight into arctic system change as a whole. The SEARCH SSC will release the goals in their revised form and then work closely with agency representatives to implement the goals through research opportunities and community activities. SEARCH is guided by a Science Steering Committee and several panels and working groups, with broad representation of the research community. SEARCH is sponsored by eight U.S. agencies, including: the National Science Foundation (NSF), the National Oceanic and Atmospheric Administration (NOAA), the National Aeronautics and Space Administration (NASA), the Department of Defense (DOD), the Department of Energy (DOE), the Department of the Interior (DOI), the Smithsonian Institution, and the U.S. Department of Agriculture (USDA). The U.S. Arctic Research Commission participates as an agency observer. For further information, please visit the website: http://www.arcus.org/search or contact: Helen V. Wiggins: helen@arcus.org, SEARCH Project Office, Arctic Research Consortium of the U.S. (ARCUS).

  17. IRIS Toxicological Review of Propionaldehyde (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of propionaldehyde that will appear on the Integrated Risk Information System (IRIS) database.

  18. IRIS Toxicological Review of Trimethylbenzenes (Interagency Science Discussion Draft)

    EPA Science Inventory

    In September 2016, EPA finalized the IRIS assessment of Trimethylbenzenes. The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices before public release in June 2016. Consistent with the May 2009 IRIS assessment development pr...

  19. 75 FR 54146 - Science Advisory Board Staff Office; Notification of a Public Meeting of the Clean Air Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ... guidance document, and pilot monitoring study can be directed to Mr. Nealson Watkins at 919-541-5522 or watkins[email protected] . Availability of Meeting Materials: The EPA draft guidance documents are posted...

  20. 75 FR 57521 - Networking and Information Technology Research and Development (NITRD) Program: Draft NITRD 2010...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... NATIONAL SCIENCE FOUNDATION Networking and Information Technology Research and Development (NITRD...) for Networking and Information Technology Research and Development (NITRD). ACTION: Notice, request.... SUMMARY: With this notice, the National Coordination Office for Networking and Information Technology...

  1. 75 FR 55360 - Networking and Information Technology Research and Development (NITRD) Program: Draft NITRD 2010...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... NATIONAL SCIENCE FOUNDATION Networking and Information Technology Research and Development (NITRD... Information Technology Research and Development (NITRD). ACTION: Notice, request for public comment. FOR..., the National Coordination Office for Networking and Information Technology Research and Development...

  2. Decision Support Framework (DSF) (Formerly Decision Support Platform)

    EPA Science Inventory

    The Science Advisory Board (SAB) provided several comments on the draft Ecosystem Services Research Program's (ESRP's) Multi-Year Plan (MYP). This presentation provides a response to comments related to the decision support framework (DSF) part of Long-Term Goal 1. The comments...

  3. Grading Written Work: An Integral Part of Writing Workshop Practice

    ERIC Educational Resources Information Center

    Robbins, Kristen

    2011-01-01

    This article chronicles how the process of reviewing and grading student written work became an integral part of a middle school teacher's writing workshop practice. In addition to discussing how reading student work can bring educators back to the heart of the profession (including the belief that spending time with drafts can reap more rewards…

  4. IRIS Toxicological Review of Chloroprene (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of chloroprene that will appear on the Integrated Risk Information System (IRIS) database.

  5. IRIS Toxicological Review of Chloroprene (2000 External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of chloroprene that will appear on the Integrated Risk Information System (IRIS) database.

  6. IRIS Toxicological Review of Trimethylbenzenes (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of trimethylbenzenes that will appear in the Integrated Risk Information System (IRIS) database.

  7. IRIS Toxicological Review of Ammonia (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of ammonia that will appear in the Integrated Risk Information System (IRIS) database.

  8. IRIS Toxicological Review of Pentachlorophenol (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of pentachlorophenol that will appear in the Integrated Risk Information System (IRIS) database.

  9. Operational Draft Regional Guidebook for the Rapid Assessment of Wetlands in the North Slope Region of Alaska

    DTIC Science & Technology

    2017-08-31

    U.S. Department of Agriculture – Natural Resources Conservation Service (USDA-NRCS); Richard Darden, USACE Alaska District; and representatives from...Slope Science Initiative USDA-NRCS U.S. Department of Agriculture – Natural Resources Conservation Service USDOI-BLM U.S. Department of the Interior... Agriculture , Forest Service, Pacific Southwest Research Station. Reddy, K. R., and R. D. DeLaune. 2008. Biogeochemistry of wetlands: Science and

  10. Supporting Research and Technology Activities for a Microwave Observing Program to Search for Extraterrestrial Intelligence

    NASA Technical Reports Server (NTRS)

    Tarter, Jill; Backus, Peter

    1995-01-01

    Curriculum materials based on the search for extraterrestrial intelligence (SETI) were developed for grades 3 through 9 science classes. The project was supported in part by NASA. Six teacher's guides, plus ancillary visuals, addressing topics in astronomy, biology, chemistry, geosciences, and physics as well as mathematics, social sciences, and language arts, were designed by a team of teachers, scientists. curriculum developers, and artists. First drafts were piloted by 10 design team teachers; revised drafts were field tested by 109 teachers in 30 states. Extensive feedback from these teachers and their students and reviews by scientists were used to revise materials prior to submission to the publisher. The field test teachers overall ranking of all guides (data from individual lesson feedback forms) was 431 on a one low to five high scale; 85% found the content appropriate to course and grade level and 75% indicated they had no reservations about using the materials again or recommending them to colleagues. The ratio of liked to disliked student responses (from 1305 student letters) was 70:30. Most recommendations from the teachers, students, and science reviewers were incorporated in the final versions for the guides, published by Libraries Unlimited/Teacher Ideas Press, 1995.

  11. IRIS Assessment Plan for Chloroform (Scoping and Problem Formulation Materials)

    EPA Science Inventory

    In September 2017, EPA released the draft IRIS Assessment Plan (IAP) for Chloroform for public review and comment. ...

  12. IRIS Assessment Plan for Chloroform (Scoping and Problem Formulation Materials)

    EPA Science Inventory

    In September 2017, EPA released the draft IRIS Assessment Plan (IAP) for Chloroform for public review and comment. Th...

  13. IRIS Toxicological Review of Trichloroethylene (Interagency Science Consultation Draft)

    EPA Science Inventory

    On November 3, 2009, the Toxicological Review of Trichloroethylene and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White Hous...

  14. IRIS Toxicological Review of Formaldehyde (Interagency Science Consultation Draft)

    EPA Science Inventory

    On June 2, 2010, the Toxicological Review of Formaldehyde and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices...

  15. Draft Benzene Case Study Review - Second Prospective Report Study Science Advisory Board Review, March 2008

    EPA Pesticide Factsheets

    EPA developed a methodology for estimating the health benefits of benzene reductions and has applied it in a metropolitan-scale case study of the benefits of CAA controls on benzene emissions to accompany the main 812 analysis.

  16. IRIS Assessment Plan for Ethylbenzene (Scoping and Problem Formulation Materials)

    EPA Science Inventory

    In September 2017, EPA released the draft IRIS Assessment Plan (IAP) for Ethylbenzene for public review and comment. ...

  17. Community Solutions for Stormwater Management: A Guide for Voluntary Long-Term Planning

    EPA Pesticide Factsheets

    This draft guide describes how to develop a comprehensive long-term community stormwater plan that integrates stormwater management with communities’ broader plans for economic development, infrastructure investment and environmental compliance.

  18. IRIS Toxicological Review of Biphenyl (External Review Draft) (September 2011)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of biphenyl that will appear in the Integrated Risk Information System (IRIS) database.

  19. Annual Plan - Fiscal Year 2009

    EPA Pesticide Factsheets

    Includes Strategic Plan Update and Draft Plans for Oversight of the American Recovery and Reinvestment Act of 2009 Based Upon the Enterprise Risk Management Integrated Framework Model Developed by the Committee of Sponsoring Orgs of the Treadway Commission

  20. IRIS Toxicological Review of n-Butanol (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of n-butanol that will appear in the Integrated Risk Information System (IRIS) database.

  1. Japan's patent issues relating to life science therapeutic inventions.

    PubMed

    Tessensohn, John A

    2014-09-01

    Japan has made 'innovation in science and technology' as one of its central pillars to ensure high growth in its next stage of economic development and its life sciences market which hosts regenerative medicine was proclaimed to be 'the best market in the world right now.' Although life science therapeutic inventions are patentable subject matter under Japanese patent law, there are nuanced obviousness and enablement challenges under Japanese patent law that can be surmounted in view of some encouraging Japanese court developments in fostering a pro-patent applicant environment in the life sciences therapeutic patent field. Nevertheless, great care must be taken when drafting and prosecuting such patent applications in the world's second most important life sciences therapeutic market.

  2. Health Assessment Document for Diesel Exhaust (Revised ...

    EPA Pesticide Factsheets

    This External Review Draft version of this assessment updates three earlier drafts (1999, 1998 and 1994) that were reviewed by the Clean Air Scientific Advisory Committee (CASAC) of the Agency's Science Advisory Board (SAB). The assessment characterizes the possible human health hazards and related exposure-response aspects of those hazards related to environmental exposure to diesel exhaust. The final assessment will incorporate peer review comments provided by the CASAC in 2000 and will take acount of public comments received during the public review period. This is a health hazard assessment. The purpose of the assessment is to identify the key health hazards associated with environmental exposure to diesel exhaust. Information from earlier draft versions of this assessment were used to support EPA regulatory decision making about emission controls for On Road Heavy Duty Diesel Engines and Off Road Diesel Engine Emissions. Also information from the assessment contributes to a nationwide analysis of air toxics to determine the highest public health priorities for future air pollution control programs.

  3. Defense Acquisitions Acronyms and Terms

    DTIC Science & Technology

    2012-12-01

    Computer-Aided Design CADD Computer-Aided Design and Drafting CAE Component Acquisition Executive; Computer-Aided Engineering CAIV Cost As an...Radiation to Ordnance HFE Human Factors Engineering HHA Health Hazard Assessment HNA Host-Nation Approval HNS Host-Nation Support HOL High -Order...Engineering Change Proposal VHSIC Very High Speed Integrated Circuit VLSI Very Large Scale Integration VOC Volatile Organic Compound W WAN Wide

  4. Scientific Uses and Directions of SPDF Data Services

    NASA Technical Reports Server (NTRS)

    Fung, Shing

    2007-01-01

    From a science user's perspective, the multi-mission data and orbit services of NASA's Space Physics Data Facility (SPDF) project perform as a working and highly functional heliophysics virtual observatory. CDAWeb enables plots, listings and file downloads for current data across the boundaries of missions and instrument types (and now including data from THEMIS and STEREO), VSPO access to a wide range of distributed data sources. SSCWeb, Helioweb and our 3D Animated Orbit Viewer (TIPSOD) provide position data and query logic for most missions currently-important to heliophysics science. OMNIWeb with its new extension to 1- and 5- minute resolution provides interplanetary parameters at the Earth's bow shock as a unique value-added data product. To enable easier integrated use of our capabilities by developers and by the emerging heliophysics VxOs, our data and services are available through webservices-based APls as well as through our direct user interfaces. SPDF has also now developed draft descriptions of its holdings in SPASE-compliant XML In addition to showcasing recent enhancements to SPDF capabilities, we will use these systems and our experience in developing them: to demonstrate a few typical science use cases; to discuss key scope and design issues among users, service providers and end data providers; and to identify key areas where existing capabilities and effective interface design are still inadequate to meet community needs.

  5. Improved motors for utility applications: Volume 6, Squirrel-cage rotor analysis: Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Griffith, J.W.; McCoy, R.M.

    1986-11-01

    An analysis of squirrel cage induction motor rotors was undertaken in response to an Industry Assessment Study finding 10% of motor failures to be rotor related. The analysis focuses on evaluating rotor design life. The evaluation combines state-of-the-art electromagnetic, thermal, and structural solution techniques into an integrated analysis and presents a simple summary. Finite element techniques are central tools in the analysis. The analysis is applied to a specific forced draft fan drive design. Fans as a category of application have a higher failure rate than other categories of power station auxiliary motor applications. Forced-draft fan drives are one ofmore » the major fan drives which accelerate a relatively high value of rotor load inertia. Various starting and operating conditions are studied for this forced-draft fan drive motor including a representative application duty cycle.« less

  6. IRIS Toxicological Review of Benzo[a]pyrene (External Review Draft)

    EPA Science Inventory

    The IRIS Toxicological Review of Benzo[a]pyrene was released for external peer review in September 2014. The EPA’s Science Advisory Board’s (SAB) Chemical Assessment Advisory Committee (CAAC) conducted a peer review of the scientific basis supporting the benzo[a]pyrene assessmen...

  7. IRIS Toxicological Review of Ammonia Noncancer Inhalation (Interagency Science Discussion Draft)

    EPA Science Inventory

    In September 2016, EPA finalized the IRIS assessment of Ammonia (Noncancer Inhalation). The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices before public release in June 2016. Consistent with the May 2009 IRIS assessment d...

  8. IRIS Toxicological Review of Urea (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 28, 2010, the Toxicological Review of Urea and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Of...

  9. IRIS Toxicological Review of 2-Hexanone (Interagency Science Discussion Draft)

    EPA Science Inventory

    On September 25, 2009, the IRIS Summary and Toxicological Review of 2-hexanone was finalized and loaded onto the IRIS database. The Toxicological Review of 2-hexanone was reviewed internally by EPA, by other federal agencies and White House Offices, by expert external peer revie...

  10. IRIS Toxicological Review of Benzo[a]pyrene (Interagency Science Discussion Draft)

    EPA Science Inventory

    In January 2017, EPA finalized the IRIS assessment of Benzo[a]pyrene. The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written...

  11. 75 FR 43981 - Science Advisory Board Staff Office; Notification of Rescheduling of Teleconference of the SAB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... Rescheduling of Teleconference of the SAB Trichloroethylene Review Panel AGENCY: Environmental Protection... rescheduling of a public teleconference of the SAB Trichloroethylene Review Panel. The teleconference... draft review report on EPA's Toxicological Review of Trichloroethylene in Support of Summary Information...

  12. 76 FR 31973 - Draft WaterSMART Strategic Implementation Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... best available science to understand the impacts of climate change on water supplies; and provide... and time. It is increasingly recognized that water is the primary means through which climate change... environment, and will identify adaptive measures needed to address climate change and future demands. Within...

  13. A Century of Being Prepared

    ERIC Educational Resources Information Center

    Ridley, Rob

    2007-01-01

    No matter the subject--be it math, science, language, art, health, drama, music, the industrial arts, business, drafting or others--experiential and environmental connections can be made. By its very definition, experiential education can provide the perfect conduit for developing knowledge about such subjects. In Ontario, there are school boards…

  14. Reference Dose for Methylmercury (External Review Draft)

    EPA Science Inventory

    In 1997, U.S. EPA issued the Mercury Study Report to Congress (MSRC). Among the assessments in the MSRC was a state-of-the-science evaluation of the health effects of methylmercury. There has been considerable discussion within the scientific community regarding the level of e...

  15. 76 FR 61092 - Notice of Intent To Prepare a Supplement to the Draft Environmental Impact Statement for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ... (SEL) re: 1[micro]Pa\\2\\-sec. The USFWS and the DoN collaborated to form the Marbled Murrelet Science... Administrative/Construction Field Office, an Inert Storage building, a Rigging Shop, and a Refit Support Facility...

  16. Engineering, global health, and inclusive innovation: focus on partnership, system strengthening, and local impact for SDGs.

    PubMed

    Clifford, Katie L; Zaman, Muhammad H

    2016-01-01

    The recent drafting of the Sustainable Development Goals challenges the research community to rethink the traditional approach to global health and provides the opportunity for science, technology, engineering, and mathematical (STEM) disciplines, particularly engineering, to demonstrate their benefit to the field. Higher education offers a platform for engineering to intersect with global health research through interdisciplinary partnerships among international universities that provide excellence in education, attract nontraditional STEM students, and foster a sense of innovation. However, a traditional lack of engineering-global health collaborations, as well as limited faculty and inadequate STEM research funding in low-income countries, has stifled progress. Still, the impact of higher education on development efforts holds great potential. This value will be realized in low-income countries through strengthening local capacity, supporting innovation through educational initiatives, and encouraging the inclusion of women and minorities in STEM programs. Current international university-level partnerships are working towards integrating engineering into global health research and strengthening STEM innovation among universities in low-income countries, but more can be done. Global health research informs sustainable development, and through integrating engineering into research efforts through university partnerships, we can accelerate progress and work towards a healthier future for all.

  17. IRIS Toxicological Review of Hexachloroethane (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of hexachloroethane that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  18. Silicon Valley Smart Corridor : draft evaluation strategy

    DOT National Transportation Integrated Search

    2000-06-05

    This document outlines the strategy for evaluating the integrated freeway, arterial, and incident management system known as the Silicon Valley Smart Corridor (SVSC). Centered in San Jose, California, the SVSC is one of approximately 65 deployments o...

  19. IRIS Toxicological Review of Libby Amphibole Asbestos (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of Libby Amphibole Asbestos that will appear in the Integrated Risk Information System (IRIS) database.

  20. IRIS Toxicological Review of Hydrogen Cyanide (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of hydrogen cyanide and cyanide salts that will appear on the Integrated Risk Information System (IRIS) database.

  1. Bundle Security Protocol for ION

    NASA Technical Reports Server (NTRS)

    Burleigh, Scott C.; Birrane, Edward J.; Krupiarz, Christopher

    2011-01-01

    This software implements bundle authentication, conforming to the Delay-Tolerant Networking (DTN) Internet Draft on Bundle Security Protocol (BSP), for the Interplanetary Overlay Network (ION) implementation of DTN. This is the only implementation of BSP that is integrated with ION.

  2. Endogenous hepadnaviruses, bornaviruses and circoviruses in snakes

    PubMed Central

    Gilbert, C.; Meik, J. M.; Dashevsky, D.; Card, D. C.; Castoe, T. A.; Schaack, S.

    2014-01-01

    We report the discovery of endogenous viral elements (EVEs) from Hepadnaviridae, Bornaviridae and Circoviridae in the speckled rattlesnake, Crotalus mitchellii, the first viperid snake for which a draft whole genome sequence assembly is available. Analysis of the draft assembly reveals genome fragments from the three virus families were inserted into the genome of this snake over the past 50 Myr. Cross-species PCR screening of orthologous loci and computational scanning of the python and king cobra genomes reveals that circoviruses integrated most recently (within the last approx. 10 Myr), whereas bornaviruses and hepadnaviruses integrated at least approximately 13 and approximately 50 Ma, respectively. This is, to our knowledge, the first report of circo-, borna- and hepadnaviruses in snakes and the first characterization of non-retroviral EVEs in non-avian reptiles. Our study provides a window into the historical dynamics of viruses in these host lineages and shows that their evolution involved multiple host-switches between mammals and reptiles. PMID:25080342

  3. Influence of the Runner Gap on the Flow Field in the Draft Tube of a Low Head Turbine

    NASA Astrophysics Data System (ADS)

    Junginger, Bernd; Riedelbauch, Stefan

    2016-11-01

    The gap flow of axial turbines is usually neglected in the design process of hydraulic machines, although it can lead to a stabilization of the draft tube flow. Though, this negligence of the gap can falsify the flow field in the draft tube. Presented in this paper are simulations of an axial propeller turbine operated at Δγ = Δγ BEP with Q > Qbep . Simulations of four gap sizes, using a mesh with about 15 million elements for the entire machine, are performed. Additionally, two turbulence models are applied, the k-ω-SST and the SAS-SST model. At the evaluated operating point a full load vortex develops. Depending on the turbulence model the developing vortex rope can either arise from the hub in a straight shape or in a shape resembling a corkscrew. Integral quantities such as head and torque are compared with experimental model test results performed in the laboratory of the Institute. Flow field simulation results are evaluated for different gap widths. Furthermore, the impact of the gap flow respectively the gap size can be observed in velocity profiles evaluated at different positions downstream the runner until to the end of the draft tube cone. Moreover, the pressure signals recorded at the beginning of the draft tube cone are also affected by the gap flow.

  4. How to Write Your First Research Paper

    PubMed Central

    Kallestinova, Elena D.

    2011-01-01

    Writing a research manuscript is an intimidating process for many novice writers in the sciences. One of the stumbling blocks is the beginning of the process and creating the first draft. This paper presents guidelines on how to initiate the writing process and draft each section of a research manuscript. The paper discusses seven rules that allow the writer to prepare a well-structured and comprehensive manuscript for a publication submission. In addition, the author lists different strategies for successful revision. Each of those strategies represents a step in the revision process and should help the writer improve the quality of the manuscript. The paper could be considered a brief manual for publication. PMID:21966034

  5. How to write your first research paper.

    PubMed

    Kallestinova, Elena D

    2011-09-01

    Writing a research manuscript is an intimidating process for many novice writers in the sciences. One of the stumbling blocks is the beginning of the process and creating the first draft. This paper presents guidelines on how to initiate the writing process and draft each section of a research manuscript. The paper discusses seven rules that allow the writer to prepare a well-structured and comprehensive manuscript for a publication submission. In addition, the author lists different strategies for successful revision. Each of those strategies represents a step in the revision process and should help the writer improve the quality of the manuscript. The paper could be considered a brief manual for publication. Copyright © 2011.

  6. A physical map of the bovine genome

    PubMed Central

    Snelling, Warren M; Chiu, Readman; Schein, Jacqueline E; Hobbs, Matthew; Abbey, Colette A; Adelson, David L; Aerts, Jan; Bennett, Gary L; Bosdet, Ian E; Boussaha, Mekki; Brauning, Rudiger; Caetano, Alexandre R; Costa, Marcos M; Crawford, Allan M; Dalrymple, Brian P; Eggen, André; Everts-van der Wind, Annelie; Floriot, Sandrine; Gautier, Mathieu; Gill, Clare A; Green, Ronnie D; Holt, Robert; Jann, Oliver; Jones, Steven JM; Kappes, Steven M; Keele, John W; de Jong, Pieter J; Larkin, Denis M; Lewin, Harris A; McEwan, John C; McKay, Stephanie; Marra, Marco A; Mathewson, Carrie A; Matukumalli, Lakshmi K; Moore, Stephen S; Murdoch, Brenda; Nicholas, Frank W; Osoegawa, Kazutoyo; Roy, Alice; Salih, Hanni; Schibler, Laurent; Schnabel, Robert D; Silveri, Licia; Skow, Loren C; Smith, Timothy PL; Sonstegard, Tad S; Taylor, Jeremy F; Tellam, Ross; Van Tassell, Curtis P; Williams, John L; Womack, James E; Wye, Natasja H; Yang, George; Zhao, Shaying

    2007-01-01

    Background Cattle are important agriculturally and relevant as a model organism. Previously described genetic and radiation hybrid (RH) maps of the bovine genome have been used to identify genomic regions and genes affecting specific traits. Application of these maps to identify influential genetic polymorphisms will be enhanced by integration with each other and with bacterial artificial chromosome (BAC) libraries. The BAC libraries and clone maps are essential for the hybrid clone-by-clone/whole-genome shotgun sequencing approach taken by the bovine genome sequencing project. Results A bovine BAC map was constructed with HindIII restriction digest fragments of 290,797 BAC clones from animals of three different breeds. Comparative mapping of 422,522 BAC end sequences assisted with BAC map ordering and assembly. Genotypes and pedigree from two genetic maps and marker scores from three whole-genome RH panels were consolidated on a 17,254-marker composite map. Sequence similarity allowed integrating the BAC and composite maps with the bovine draft assembly (Btau3.1), establishing a comprehensive resource describing the bovine genome. Agreement between the marker and BAC maps and the draft assembly is high, although discrepancies exist. The composite and BAC maps are more similar than either is to the draft assembly. Conclusion Further refinement of the maps and greater integration into the genome assembly process may contribute to a high quality assembly. The maps provide resources to associate phenotypic variation with underlying genomic variation, and are crucial resources for understanding the biology underpinning this important ruminant species so closely associated with humans. PMID:17697342

  7. IRIS Toxicological Review of cis- & trans-1,2-Dichloroethylene (Interagency Science Consultation Draft)

    EPA Science Inventory

    On September 24, 2009, the Toxicological Review of cis- and trans-1,2-dichloroethylene and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal ag...

  8. IRIS Toxicological Review of Tert-Butyl Alcohol (Tert-Butanol) (External Review Draft)

    EPA Science Inventory

    The IRIS Toxicological Review of tert-Butyl Alcohol (tert-Butanol) was released for external peer review in June 2017. EPA’s Science Advisory Board’s (SAB) Chemical Assessment Advisory Committee (CAAC) will conduct a peer review of the scientific basis supporting ...

  9. IRIS Toxicological Review of 1,2,3-trichloropropane (Interagency Science Discussion Draft)

    EPA Science Inventory

    On September 30, 2009, the IRIS Summary and Toxicological Review of 1,2,3-trichloropropane (TCP) was finalized and loaded onto the IRIS database. The Toxicological Review of TCP was reviewed internally by EPA, by other federal agencies and White House Offices, by expert external...

  10. 75 FR 16108 - Science Advisory Board Staff Office; Notification of a Public Teleconference and Public Meeting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... Information System (IRIS) is an electronic database containing descriptive and quantitative toxicological... Office of Research and Development (ORD). In 2001, ORD developed a draft IRIS Toxicological Assessment..., the National Research Council (NRC) was requested to provide a scientific consultation on key...

  11. Marine Ecology Research Resource Units Grades 7-9. Draft.

    ERIC Educational Resources Information Center

    Contra Costa County Dept. of Education, Pleasant Hill, CA.

    Project Marine Ecology Research (MER) is an ecological unit designed to involve secondary students in the study of the marine biome. The teachers are also involved with MER through inservice participation and materials preparation. The unit is designed to be incorporated within the existing science curriculum. Specifically, the activities concern…

  12. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (External Review Draft)

    EPA Science Inventory

    The IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) was released for external peer review in June 2017. EPA’s Science Advisory Board’s (SAB) Chemical Assessment Advisory Committee (CAAC) will conduct a peer review of the scientific basis supporting the ETB...

  13. Genome sequence of a Providencia stuartii strain isolated from Lucilia sericata salivary glands

    USDA-ARS?s Scientific Manuscript database

    We present the draft genome sequence of a Providencia stuartii strain derived from salivary glands of larval Lucilia sericata; a common blow fly important to forensic, medical and veterinary science. The genome sequence will help dissect coinfections involving Providencia stuartii and Proteus mirab...

  14. Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide (2016 Interagency Science Discussion Draft)

    EPA Science Inventory

    In December 2016, EPA finalized its Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide. EPA’s evaluation was reviewed internally by EPA and by other federal agencies and White House Offices in October 2016, before public release. Consistent with the May 2009 IRIS asse...

  15. IRIS Assessment Plan for Nitrate and Nitrite (Scoping and Problem Formulation Materials)

    EPA Science Inventory

    In September 2017, EPA released the draft IRIS Assessment Plan (IAP) for Nitrate and Nitrite for public review and comment. This document was discussed at an EPA Science Advisory Board (SAB) Chemical Assessment Advisory Committee (CAAC) meeting on September 27-28, 2017....

  16. Solar tower enhanced natural draft dry cooling tower

    NASA Astrophysics Data System (ADS)

    Yang, Huiqiang; Xu, Yan; Acosta-Iborra, Alberto; Santana, Domingo

    2017-06-01

    Concentrating Solar Power (CSP) plants are located in desert areas where the Direct Normal Irradiance (DNI) value is very high. Since water resource is scarcely available, mechanical draft cooing technology is commonly used, with power consumption of mechanical fans being approximately 2% of the total power generated. Today, there is only one solar power plant (Khi Solar One in South Africa) uses a condenser installed in a Natural Draft Cooling (NDC) tower that avoids the windage loss of water occurring in wet cooling towers. Although, Khi Solar One is a cavity receiver power tower, the receivers can be hung onto the NDC tower. This paper looks at a novel integration of a NDC tower into an external molten salt receiver of a solar power plant, which is one of a largest commercial molten salt tower in China, with 100MWe power capacity. In this configuration study, the NDC tower surrounds the concrete tower of the receiver concentrically. In this way, the receiver concrete tower is the central support of the NDC tower, which consists of cable networks that are fixed to the concrete tower and suspended at a certain height over the floor. The cable networks support the shell of the NDC tower. To perform a preliminary analysis of the behavior of this novel configuration, two cases of numerical simulation in three dimensional (3D) models have been solved using the commercial Computational Fluid Dynamics (CFD) code, ANSYS Fluent 6.3. The results show that the integration of the NDC tower into an external central receiver tower is feasible. Additionally, the total heat transfer rate is not reduced but slightly increases when the molten salt receiver is in operation because of the additional natural draft induced by the high temperature of the receiver.

  17. REVIEW OF DRAFT REVISED BLUE BOOK ON ESTIMATING ...

    EPA Pesticide Factsheets

    In 1994, EPA published a report, referred to as the “Blue Book,” which lays out EPA’s current methodology for quantitatively estimating radiogenic cancer risks. A follow-on report made minor adjustments to the previous estimates and presented a partial analysis of the uncertainties in the numerical estimates. In 2006, the National Research Council of the National Academy of Sciences released a report on the health risks from exposure to low levels of ionizing radiation. Cosponsored by the EPA and several other Federal agencies, Health Risks from Exposure to Low Levels of Ionizing Radiation BEIR VII Phase 2 (BEIR VII) primarily addresses cancer and genetic risks from low doses of low-LET radiation. In the draft White Paper: Modifying EPA Radiation Risk Models Based on BEIR VII (White Paper), ORIA proposed changes in EPA’s methodology for estimating radiogenic cancers, based on the contents of BEIR VII and some ancillary information. For the most part, it proposed to adopt the models and methodology recommended in BEIR VII; however, certain modifications and expansions are considered to be desirable or necessary for EPA’s purposes. EPA sought advice from the Agency’s Science Advisory Board on the application of BEIR VII and on issues relating to these modifications and expansions in the Advisory on EPA’s Draft White Paper: Modifying EPA Radiation Risk Models Based on BEIR VII (record # 83044). The SAB issued its Advisory on Jan. 31, 2008 (EPA-SAB-08-

  18. IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Dichloromethane that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  19. IRIS Toxicological Review of Tetrahydrofuran (THF) (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of tetrahydrofuran (THF) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  20. IRIS Toxicological Review of Trichloroethylene (TCE) (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Trichloroethylene (TCE) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  1. IRIS Toxicological Review of Cerium Oxide and Cerium Compounds (External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of cerium oxide and cerium compounds that will appear on the Integrated Risk Information System (IRIS) database.

  2. A Survey of CAD/CAM Technology Applications in the U.S. Shipbuilding Industry

    DTIC Science & Technology

    1984-01-01

    operation for drafting. Computer Aided Engineering (CAE) analysis is used primarily to determine the validity of design characteristics and produc- tion...include time standard generation, sea trial analysis , and group Systems integration While no systems surveyed Aided Design (CAD) is the technology... analysis . is the largest problem involving software packages. are truly integrated, many are interfaced. Computer most interfaced category with links

  3. Comments on the Draft U.S. EPA Document Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the Integrated Risk Information System (IRIS)

    EPA Pesticide Factsheets

    The Organic Arsenical Products Task Force (OAPTF) hereby submits the appended list of materials from the scientific literature on inorganic arsenic for inclusion in the U.S. Environmental Protection Agency's (EPA) docket maintained in support of the Summary Information on the Integrated Risk Information System (IRIS) Report (Report)

  4. a New Animation of Subduction Processes for Undergraduates

    NASA Astrophysics Data System (ADS)

    Stern, R. J.; Lieu, W. K.; Mantey, A.; Ward, A.; Todd, F.; Farrar, E.; Sean, M.; Windler, J.

    2015-12-01

    The subduction of oceanic lithosphere beneath convergent plate margins is a fundamental plate tectonic concept and an important Earth process. It is responsible for some of Earth's most dangerous natural hazards including earthquakes and volcanic eruptions but also produced the continental crust and important mineral deposits. A range of geoscientific efforts including NSF MARGINS and GeoPRISMS initiatives have advanced our understanding of subduction zone processes. In spite the importance of subduction zones and our advancing understanding of how these function, there are few animations that clearly explain the subduction process to non-expert audiences. This deficiency reflects the disparate expertises between geoscientists who know the science but have weak animation skills and digital artists and animators who have strong skills in showing objects in motion but are not experts in natural processes like plate tectonics. This transdisciplinary gap can and should be bridged. With a small grant from NSF (DUE-1444954) we set about to generate a realistic subduction zone animation aimed at the university undergraduate audience by first working within our university to rough out a draft animation and then contract a professional to use this to construct the final version. UTD Geosciences faculty (Stern) and graduate student (Lieu) teamed up with faculty from UTD School of Arts, Technology, and Emerging Communication (ATEC)(Farrar, Fechter, and McComber) to identify and recruit talented ATEC undergraduate students (Mantey, Ward) to work on the project. Geoscientists assembled a storyboard and met weekly with ATEC undergraduates to generate a first draft of the animation, which guided development of an accompanying narrative. The draft animation with voice-over was then handed off to professional animator Windler (Archistration CG) to generate the final animation. We plan to show both the student-generated draft version and the final animation during our presentation. The final animation will be freely available via the internet and will also be used as a supplement for McGraw-Hill textbooks in oceanography, physical geology, Earth science, geography, historical geology, natural hazards, and natural resources.

  5. IRIS Toxicological Review of Methanol (External Review Draft, 2013)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of methanol (non-cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  6. IRIS Toxicological Review of Trichloroacetic Acid (TCA) (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Trichloroacetic acid (TCA) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  7. 76 FR 11216 - Notice of Public Meetings for the Draft Environmental Impact Statement for Land Acquisition and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-01

    ... full integration of MEB-sized Aviation Combat Element operations and both air- and ground-delivered...-scale MEB Exercise conducted twice per year for 24 continuous days each. Current levels of proficiency...

  8. IRIS Toxicological Review of 1,1,2,2-Tetrachloroethane (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,1,2,2-tetrachloroethane that will appear on the Integrated Risk Information System (IRIS) database.

  9. IRIS Toxicological Review of Cis-& Trans-1,2-Dichloroethylene (External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of cis- and trans-1,2-dichloroethylene that will appear in the Integrated Risk Information System (IRIS) database.

  10. IRIS Toxicological Review of Formaldehyde (Inhalation) (External Review Draft 2010)

    EPA Science Inventory

    UPDATE EPA is currently revising its Integrated Risk Information System (IRIS) assessment of formaldehyde to address the 2011 NAS peer review recommendations. This assessment addresses both noncancer and cancer human health effects that are relevant to assessing ...

  11. IRIS Toxicological Review of Beryllium and Compounds (2008 External Review Draft)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of Beryllium that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  12. Evaluation of the Carcinogenicity of Ethylene Oxide (2006 External Review Draft)

    EPA Science Inventory

    EPA conducted a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of ethylene oxide (cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  13. IRIS Toxicological Review of Ethylene Glycol Mono-Butyl Ether (Egbe) (External Review Draft)

    EPA Science Inventory

    EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of ethylene glycol monobutyl ether that will appear on the Integrated Risk Information System (IRIS) database.

  14. Ready to put metadata on the post-2015 development agenda? Linking data publications to responsible innovation and science diplomacy.

    PubMed

    Özdemir, Vural; Kolker, Eugene; Hotez, Peter J; Mohin, Sophie; Prainsack, Barbara; Wynne, Brian; Vayena, Effy; Coşkun, Yavuz; Dereli, Türkay; Huzair, Farah; Borda-Rodriguez, Alexander; Bragazzi, Nicola Luigi; Faris, Jack; Ramesar, Raj; Wonkam, Ambroise; Dandara, Collet; Nair, Bipin; Llerena, Adrián; Kılıç, Koray; Jain, Rekha; Reddy, Panga Jaipal; Gollapalli, Kishore; Srivastava, Sanjeeva; Kickbusch, Ilona

    2014-01-01

    Metadata refer to descriptions about data or as some put it, "data about data." Metadata capture what happens on the backstage of science, on the trajectory from study conception, design, funding, implementation, and analysis to reporting. Definitions of metadata vary, but they can include the context information surrounding the practice of science, or data generated as one uses a technology, including transactional information about the user. As the pursuit of knowledge broadens in the 21(st) century from traditional "science of whats" (data) to include "science of hows" (metadata), we analyze the ways in which metadata serve as a catalyst for responsible and open innovation, and by extension, science diplomacy. In 2015, the United Nations Millennium Development Goals (MDGs) will formally come to an end. Therefore, we propose that metadata, as an ingredient of responsible innovation, can help achieve the Sustainable Development Goals (SDGs) on the post-2015 agenda. Such responsible innovation, as a collective learning process, has become a key component, for example, of the European Union's 80 billion Euro Horizon 2020 R&D Program from 2014-2020. Looking ahead, OMICS: A Journal of Integrative Biology, is launching an initiative for a multi-omics metadata checklist that is flexible yet comprehensive, and will enable more complete utilization of single and multi-omics data sets through data harmonization and greater visibility and accessibility. The generation of metadata that shed light on how omics research is carried out, by whom and under what circumstances, will create an "intervention space" for integration of science with its socio-technical context. This will go a long way to addressing responsible innovation for a fairer and more transparent society. If we believe in science, then such reflexive qualities and commitments attained by availability of omics metadata are preconditions for a robust and socially attuned science, which can then remain broadly respected, independent, and responsibly innovative. "In Sierra Leone, we have not too much electricity. The lights will come on once in a week, and the rest of the month, dark[ness]. So I made my own battery to power light in people's houses." Kelvin Doe (Global Minimum, 2012) MIT Visiting Young Innovator Cambridge, USA, and Sierra Leone "An important function of the (Global) R&D Observatory will be to provide support and training to build capacity in the collection and analysis of R&D flows, and how to link them to the product pipeline." World Health Organization (2013) Draft Working Paper on a Global Health R&D Observatory.

  15. Collection of Arctic Ocean Data from US Navy Submarines on the New SCICEX Program

    NASA Astrophysics Data System (ADS)

    Smethie, W. M.; Sambrotto, R.; Boyd, T.; Richter-Menge, J.; Corbett, J.

    2011-12-01

    The SCICEX submarine Arctic science program originated in the 1990s when six dedicated science cruises were conducted in the Arctic Ocean aboard US Navy Sturgeon class submarines. After the cold war era Sturgeon class submarines were retired, several Science Accommodation cruises, for which a few days for scientific measurements were added to planned submarine transits through the Arctic Ocean, were carried out when opportunities arose. Renewed interest in conducting further Science Accommodation cruises on a regular basis to better document and understand how the Arctic Ocean responds to climate change resulted in publication of a scientific plan in 2010 (http://www.arctic.gov/publications/scicex_plan.pdf). In the spring of 2011 testing of data collection and water sampling methods aboard newer Virginia and Seawolf class submarines on transit from a Navy ice camp in the Beaufort Sea, was conducted in order to develop protocols and evaluate techniques. Ice draft measurements were also taken in the vicinity of the ice camp and near the North Pole to evaluate new data collection systems. This evaluation will include a comparison of the ice draft data with a comprehensive set of in situ ice thickness measurements taken near the ice camp. Under-ice submarine-launched eXpendable Condutivity Temperature Depth (XCTD) probes were deployed from the USS Connecticut (SSN-22), a Seawolf class submarine, and the resulting profiles compared to CTD casts from the APLIS ice station and historical profiles. Water samples were collected through the hull for measurements of tritium, helium isotopes, oxygen isotopes, chlorofluorocarbons, sulfur hexafluoride, nutrients, dissolved organic carbon, bacterioplankton, phytoplankton and particulates levels. These samples were returned to Lamont-Doherty Earth Observatory and were in the process of being measured at the time this abstract was written. Measurements completed at this time indicate good samples can be collected for CFC-12, nutrients and biological and inorganic particulates. Measurements of the other samples will be completed and reported on at the meeting. Early results indicate that both of the submarine types evaluated are capable of reliably collecting important information on water temperature, salinity, tracers, chemistry, and biology and ice draft.

  16. A student guide to proofreading and writing in science.

    PubMed

    Hyatt, Jon-Philippe K; Bienenstock, Elisa Jayne; Tilan, Jason U

    2017-09-01

    Scientific writing requires a distinct style and tone, whether the writing is intended for an undergraduate assignment or publication in a peer-reviewed journal. From the first to the final draft, scientific writing is an iterative process requiring practice, substantial feedback from peers and instructors, and comprehensive proofreading on the part of the writer. Teaching writing or proofreading is not common in university settings. Here, we present a collection of common undergraduate student writing mistakes and put forth suggestions for corrections as a first step toward proofreading and enhancing readability in subsequent draft versions. Additionally, we propose specific strategies pertaining to word choice, structure, and approach to make products more fluid and focused for an appropriate target audience. Copyright © 2017 the American Physiological Society.

  17. Design Drafting. COM-LINK. Competency Based Vocational Curricula with Basic Skills and Academic Linkages.

    ERIC Educational Resources Information Center

    Sharkey, Jeff

    This competency-based module uses the Ocean County (New Jersey) Vocational-Technical Schools curriculum-infused model for infusing basic skills instruction into vocational education. The model demonstrates the relationship of vocational skills to communication, mathematics, and science. The document begins with a philosophy statement; preface; a…

  18. Unit: Tuning in With Our Senses, Inspection Set, National Trial Print.

    ERIC Educational Resources Information Center

    Australian Science Education Project, Toorak, Victoria.

    A preliminary version of this trial draft of a unit prepared for Australian secondary science students was previously announced as ED 049 931 under the short title of "Messengers." The teachers' guide is an overprinted version of the students' booklet, and lists objectives for each section of the materials, indicates possible teaching…

  19. 77 FR 53908 - Winter Use Plan, Supplemental Draft Environmental Impact Statement, Yellowstone National Park

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... whether to use their daily allocation of transportation events for snowmobiles or snowcoaches, but no more than 50 daily transportation events could come from snowmobiles. OSV use would continue to be 100..., Associate Director, Natural Resource Stewardship and Science National Park Service. [FR Doc. 2012-21829...

  20. 76 FR 17649 - Science Advisory Board Staff Office; Request for Nominations; SAB Mercury Review Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-30

    ... responding to an EPA request for peer review of a March 2011 draft risk assessment for mercury, entitled Technical Support Document: National-Scale Mercury Risk Assessment Supporting the Appropriate and Necessary... a proposed rule concerning regulation of hazardous air pollutants (HAPs) released from coal-burning...

  1. Drafting and Acting on Feedback Supports Student Learning when Writing Essay Assignments

    ERIC Educational Resources Information Center

    Freestone, Nicholas

    2009-01-01

    A diverse student population is a relatively recent feature of the higher education system in the United Kingdom. Consequently, it may be thought that more "traditional" types of assessment based around essay writing skills for science undergraduates may be of decreasing value and relevance to contemporary students. This article…

  2. A Draft Science Management Plan for Returned Samples from Mars: Recommendations from the International Mars Architecture for the Return of Samples (iMARS) Phase II Working Group

    NASA Astrophysics Data System (ADS)

    Haltigin, T.; Lange, C.; Mugnuolo, R.; Smith, C.

    2018-04-01

    This paper summarizes the findings and recommendations of the International Mars Architecture for the Return of Samples (iMARS) Phase II Working Group, an international team comprising 38 members from 16 countries and agencies.

  3. Notification of SAB Workgroup Public Meeting for the Toxicological Review of Inorganic Arsenic

    EPA Pesticide Factsheets

    Organic Arsenical Products Task Force (OAPTF), a group of registrants of pesticide products that contain monosodium methanearsonate (MSMA), to request that the Science Advisory Board (SAB) reschedule the public meeting of a workgroup to conduct a review of the draft document entitled Toxicological Review of Inorganic Arsenic

  4. The Effects of Mountaintop Mines and Valley Fills on Aquatic Ecosystems of the Central Appalachian Coalfields (External Review Draft)

    EPA Science Inventory

    This report assesses the state of the science on the environmental impacts of mountaintop mines and valley fills (MTM-VF) on streams in the Central Appalachian Coalfields. Our review focused on the aquatic impacts of mountaintop removal coal mining, which, as its name suggests, ...

  5. 78 FR 51719 - Draft Toxicological Review of Benzo[a]pyrene: In Support of the Summary Information in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... Environmental Assessment (NCEA) within the EPA Office of Research and Development (ORD). EPA is releasing this... Program is a human health assessment program that evaluates quantitative and qualitative risk information... IRIS Program, EPA provides the highest quality science-based human health assessments to support the...

  6. 75 FR 7477 - Draft Toxicological Review of Inorganic Arsenic: In Support of the Summary Information on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... Environmental Assessment (NCEA) within the EPA's Office of Research and Development (ORD). The Toxicological Review of Inorganic Arsenic was submitted to the EPA's Science Advisory Board (SAB) for external peer... IRIS IRIS is a human health assessment program that evaluates quantitative and qualitative risk...

  7. Federal global change data plan reviewed

    NASA Astrophysics Data System (ADS)

    Simarski, Lynn Teo

    1992-02-01

    Scientists and data managers are grappling with an unprecedented challenge: how to handle the explosion of data being produced by global change research. The federal government is developing a plan to manage data among the various federal agencies that participate in the U.S. Global Change Research Program. From January 22 to 24, some 80 scientists, data managers, and officials from federal agencies, universities, laboratories, and other institutions met in Washington, D.C. to critique the draft plan. New observational tools are expected to increase the flow of global change data to ever more massive proportions, while all the data now available is not catalogued properly. Even now, if a researcher does manage to find appropriate data, it may not be documented sufficiently to use. “These practical difficulties are especially acute for global change researchers, who need to search for data and information very broadly across scientific disciplines and sometimes decades after the data were archived,” explains the draft plan by the Committee on Earth and Environmental Sciences of the Office of Science and Technology Policy.

  8. Sequence-based Network Completion Reveals the Integrality of Missing Reactions in Metabolic Networks*

    PubMed Central

    Krumholz, Elias W.; Libourel, Igor G. L.

    2015-01-01

    Genome-scale metabolic models are central in connecting genotypes to metabolic phenotypes. However, even for well studied organisms, such as Escherichia coli, draft networks do not contain a complete biochemical network. Missing reactions are referred to as gaps. These gaps need to be filled to enable functional analysis, and gap-filling choices influence model predictions. To investigate whether functional networks existed where all gap-filling reactions were supported by sequence similarity to annotated enzymes, four draft networks were supplemented with all reactions from the Model SEED database for which minimal sequence similarity was found in their genomes. Quadratic programming revealed that the number of reactions that could partake in a gap-filling solution was vast: 3,270 in the case of E. coli, where 72% of the metabolites in the draft network could connect a gap-filling solution. Nonetheless, no network could be completed without the inclusion of orphaned enzymes, suggesting that parts of the biochemistry integral to biomass precursor formation are uncharacterized. However, many gap-filling reactions were well determined, and the resulting networks showed improved prediction of gene essentiality compared with networks generated through canonical gap filling. In addition, gene essentiality predictions that were sensitive to poorly determined gap-filling reactions were of poor quality, suggesting that damage to the network structure resulting from the inclusion of erroneous gap-filling reactions may be predictable. PMID:26041773

  9. The science writing tool

    NASA Astrophysics Data System (ADS)

    Schuhart, Arthur L.

    This is a two-part dissertation. The primary part is the text of a science-based composition rhetoric and reader called The Science Writing Tool. This textbook has seven chapters dealing with topics in Science Rhetoric. Each chapter includes a variety of examples of science writing, discussion questions, writing assignments, and instructional resources. The purpose of this text is to introduce lower-division college science majors to the role that rhetoric and communication plays in the conduct of Science, and how these skills contribute to a successful career in Science. The text is designed as a "tool kit," for use by an instructor constructing a science-based composition course or a writing-intensive Science course. The second part of this part of this dissertation reports on student reactions to draft portions of The Science Writing Tool text. In this report, students of English Composition II at Northern Virginia Community College-Annandale were surveyed about their attitudes toward course materials and topics included. The findings were used to revise and expand The Science Writing Tool.

  10. The Quantum Leap in Special Education: New Information and Communication Technologies. Their Impact upon Educational Opportunities for Disabled People, Focussing on How Integration in the Ordinary Educational System Can Be Facilitated. Draft Document.

    ERIC Educational Resources Information Center

    Kristiansen, Rolf

    This paper suggests means of merging educational ideas with new information and communication technologies to aid individuals with disabilities. New technologies discussed include microtechnology and integrated circuits, high speed processing and retrieval of information, and light-weight equipment, among others. New technologies can be used as…

  11. IRIS Toxicological Review of 1,4-Dioxane (External Review Draft, 2009)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of 1,4-dioxane that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  12. Computer-Integrated Manufacturing Technology. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Lakeland Tech Prep Consortium, Kirtland, OH.

    This tech prep competency profile covers these occupations: manufacturing technician, computer-assisted design and drafting (CADD) technician, quality technician, and mechanical technician. Section 1 provides occupation definitions. Section 2 lists development committee members. Section 3 provides the leveling codes---abbreviations for grade level…

  13. IRIS Toxicological Review of Methanol (Non-Cancer) (External Review Draft; April 2011)

    EPA Science Inventory

    EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of methanol (non-cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

  14. Drafting and acting on feedback supports student learning when writing essay assignments.

    PubMed

    Freestone, Nicholas

    2009-06-01

    A diverse student population is a relatively recent feature of the higher education system in the United Kingdom. Consequently, it may be thought that more "traditional" types of assessment based around essay writing skills for science undergraduates may be of decreasing value and relevance to contemporary students. This article describes a study in which the process of feedback on, and associated redrafting of, an essay was closely supervised to improve essay writing skills and subsequent exam performance. The results of this study show that students can significantly improve their learning and academic performance, as assessed by final examination mark, by a process that more closely mimics a "real-world" situation of review and redrafting. Additionally, the data show that students benefit from feedback only when this is used appropriately by the student. The article also discusses the continuing importance and relevance of essay writing skills so that writing, and acting upon feedback to do with that writing, remains an integral part of the process of learning.

  15. It's Time to Develop a New "Draft Test Protocol" for a Mars Sample Return Mission (or Two…).

    PubMed

    Rummel, John D; Kminek, Gerhard

    2018-04-01

    The last time NASA envisioned a sample return mission from Mars, the development of a protocol to support the analysis of the samples in a containment facility resulted in a "Draft Test Protocol" that outlined required preparations "for the safe receiving, handling, testing, distributing, and archiving of martian materials here on Earth" (Rummel et al., 2002 ). This document comprised a specific protocol to be used to conduct a biohazard test for a returned martian sample, following the recommendations of the Space Studies Board of the US National Academy of Sciences. Given the planned launch of a sample-collecting and sample-caching rover (Mars 2020) in 2 years' time, and with a sample return planned for the end of the next decade, it is time to revisit the Draft Test Protocol to develop a sample analysis and biohazard test plan to meet the needs of these future missions. Key Words: Biohazard detection-Mars sample analysis-Sample receiving facility-Protocol-New analytical techniques-Robotic sample handling. Astrobiology 18, 377-380.

  16. Ethics in health sciences librarianship.

    PubMed Central

    Hurych, J M; Glenn, A C

    1987-01-01

    Against a background of discussion about drafting of an ethical code for librarians and a review of articles confronting ethical issues in librarianship, the authors surveyed the 150 institutional members of the Health Science Librarians of Illinois (HSLI) regarding their perceptions of ethical concerns. Among the issues addressed in the survey are library organization, personnel policies, and professional competency, along with the traditional concerns of professional versus personal values, privacy and confidentiality, access to materials, and materials selection criteria in a health sciences context. Based on a 60% response rate, survey results indicate widespread agreement on some issues and a conspicuous lack of consensus on others. Further research is suggested in order to assess the need for a separate ethical code for health sciences librarians. PMID:3450346

  17. Weather information for surface transportation : a white paper on needs, issues and actions : draft (revised)

    DOT National Transportation Integrated Search

    1998-05-15

    This White Paper focuses on the needs of surface transportation decisions for better support by weather information, integrated with other information in the ITS. Findings are included from a special team workshop and feedback from conference present...

  18. 76 FR 19095 - Pesticide Program Dialogue Committee; Notice of Public Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-06

    ... EPA Administrator on issues associated with pesticide regulatory development and reform initiatives... Program Dialogue Committee (PPDC) is scheduled for April 20-21, 2011. A draft agenda is under development that will include Integrated Pest Management, Pollinator Protection, Children/Worker Risk Policy...

  19. Endogenous hepadnaviruses, bornaviruses and circoviruses in snakes.

    PubMed

    Gilbert, C; Meik, J M; Dashevsky, D; Card, D C; Castoe, T A; Schaack, S

    2014-09-22

    We report the discovery of endogenous viral elements (EVEs) from Hepadnaviridae, Bornaviridae and Circoviridae in the speckled rattlesnake, Crotalus mitchellii, the first viperid snake for which a draft whole genome sequence assembly is available. Analysis of the draft assembly reveals genome fragments from the three virus families were inserted into the genome of this snake over the past 50 Myr. Cross-species PCR screening of orthologous loci and computational scanning of the python and king cobra genomes reveals that circoviruses integrated most recently (within the last approx. 10 Myr), whereas bornaviruses and hepadnaviruses integrated at least approximately 13 and approximately 50 Ma, respectively. This is, to our knowledge, the first report of circo-, borna- and hepadnaviruses in snakes and the first characterization of non-retroviral EVEs in non-avian reptiles. Our study provides a window into the historical dynamics of viruses in these host lineages and shows that their evolution involved multiple host-switches between mammals and reptiles. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  20. Digital pathology: DICOM-conform draft, testbed, and first results.

    PubMed

    Zwönitzer, Ralf; Kalinski, Thomas; Hofmann, Harald; Roessner, Albert; Bernarding, Johannes

    2007-09-01

    Hospital information systems are state of the art nowadays. Therefore, Digital Pathology, also labelled as Virtual Microscopy, has gained increased attention. Triggered by radiology, standardized information models and workflows were world-wide defined based on DICOM. However, DICOM-conform integration of Digital Pathology into existing clinical information systems imposes new problems requiring specific solutions concerning the huge amount of data as well as the special structure of the data to be managed, transferred, and stored. We implemented a testbed to realize and evaluate the workflow of digitized slides from acquisition to archiving. The experiences led to the draft of a DICOM-conform information model that accounted for extensions, definitions, and technical requirements necessary to integrate digital pathology in a hospital-wide DICOM environment. Slides were digitized, compressed, and could be viewed remotely. Real-time transfer of the huge amount of data was optimized using streaming techniques. Compared to a recent discussion in the DICOM Working Group for Digital Pathology (WG26) our experiences led to a preference of a JPEG2000/JPIP-based streaming of the whole slide image. The results showed that digital pathology is feasible but strong efforts by users and vendors are still necessary to integrate Digital Pathology into existing information systems.

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