77 FR 48177 - Fuel Oil Systems for Emergency Power Supplies

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-13

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0159] Fuel Oil Systems for Emergency Power Supplies AGENCY: Nuclear Regulatory Commission. ACTION: Draft regulatory guide; extension of comment period. SUMMARY: On... Regulatory Guide, DG- 1282, ``Fuel Oil Systems for Emergency Power Supplies,'' in the Federal Register for a...

76 FR 11288 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-01

... Guide, DG-7008, ``Leakage Tests on Packages for Shipment of Radioactive Materials.'' FOR FURTHER... regulatory guide (DG), entitled, ``Leakage Tests on Packages for Shipment of Radioactive Materials'' is... Radioactive and Nonnuclear Hazardous Materials, N14, Subcommittee of the American National Standards Institute...

Application of USNRC NUREG/CR-6661 and draft DG-1108 to evolutionary and advanced reactor designs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang 'Apollo', Chen

2006-07-01

For the seismic design of evolutionary and advanced nuclear reactor power plants, there are definite financial advantages in the application of USNRC NUREG/CR-6661 and draft Regulatory Guide DG-1108. NUREG/CR-6661, 'Benchmark Program for the Evaluation of Methods to Analyze Non-Classically Damped Coupled Systems', was by Brookhaven National Laboratory (BNL) for the USNRC, and Draft Regulatory Guide DG-1108 is the proposed revision to the current Regulatory Guide (RG) 1.92, Revision 1, 'Combining Modal Responses and Spatial Components in Seismic Response Analysis'. The draft Regulatory Guide DG-1108 is available at http://members.cox.net/apolloconsulting, which also provides a link to the USNRC ADAMS site to searchmore » for NUREG/CR-6661 in text file or image file. The draft Regulatory Guide DG-1108 removes unnecessary conservatism in the modal combinations for closely spaced modes in seismic response spectrum analysis. Its application will be very helpful in coupled seismic analysis for structures and heavy equipment to reduce seismic responses and in piping system seismic design. In the NUREG/CR-6661 benchmark program, which investigated coupled seismic analysis of structures and equipment or piping systems with different damping values, three of the four participants applied the complex mode solution method to handle different damping values for structures, equipment, and piping systems. The fourth participant applied the classical normal mode method with equivalent weighted damping values to handle differences in structural, equipment, and piping system damping values. Coupled analysis will reduce the equipment responses when equipment, or piping system and structure are in or close to resonance. However, this reduction in responses occurs only if the realistic DG-1108 modal response combination method is applied, because closely spaced modes will be produced when structure and equipment or piping systems are in or close to resonance. Otherwise, the conservatism in the current Regulatory Guide 1.92, Revision 1, will overshadow the advantage of coupled analysis. All four participants applied the realistic modal combination method of DG-1108. Consequently, more realistic and reduced responses were obtained. (authors)« less

76 FR 14108 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-15

..., Revision 1, ``Control of Preheat Temperature for Welding of Low-Alloy Steel.'' FOR FURTHER INFORMATION... for Welding of Low-Alloy Steel,'' was issued with a temporary identification as Draft Regulatory Guide... implementing regulatory requirements related to the control of welding for low-alloy steel components during...

76 FR 24538 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... Guide, DG-1264, ``Thermal Overload Protection for Electric Motors On Motor- Operated Valves.'' FOR FURTHER INFORMATION CONTACT: Darrell Murdock, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001, telephone: 301-251- 7629 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I...

78 FR 37848 - ASME Code Cases Not Approved for Use

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-24

...The U.S. Nuclear Regulatory Commission (NRC) is issuing for public comment draft regulatory guide (DG), DG-1233, ``ASME Code Cases not Approved for Use.'' This regulatory guide lists the American Society of Mechanical Engineers (ASME) Code Cases that the NRC has determined not to be acceptable for use on a generic basis.

75 FR 81675 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-28

... Fuel Cycle Facilities.'' FOR FURTHER INFORMATION CONTACT: Mekonen M. Bayssie, Regulatory Guide... Materials in Liquid and Gaseous Effluents from Nuclear Fuel Cycle Facilities,'' was published as Draft... guidance is applicable to nuclear fuel cycle facilities, with the exception of uranium milling facilities...

75 FR 35508 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-22

... Systems and Networks,'' requires licensees to develop cyber-security plans and programs to protect critical digital assets, including digital safety systems, from malicious cyber attacks. Regulatory Guide 5.71, ``Cyber Security Programs for Nuclear Facilities,'' provides guidance to meet the requirements of...

75 FR 11574 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-11

... agency's ``Regulatory Guide'' series. This series was developed to describe and make available to the... protection during plant operation and maintenance activities. For plants that have a design basis that... coatings be qualified and capable of surviving a design-basis accident without adversely affecting safety...

76 FR 55137 - Monitoring the Effectiveness of Maintenance at Nuclear Power Plants

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-06

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0212] Monitoring the Effectiveness of Maintenance at... comment draft regulatory guide (DG) DG-1278, ``Monitoring the Effectiveness of Maintenance at Nuclear Power Plants.'' This guide endorses Revision 4A to Nuclear Management and Resources Council (NUMARC) 93...

76 FR 10917 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-28

... in the agency's ``Regulatory Guide'' series. This series was developed to describe and make available... connection assemblies can perform their safety functions during and after a design-basis event. Title 10 of... Reprocessing Plants,'' Criterion III, ``Design Control,'' requires, in part, that test programs used to verify...

75 FR 16516 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-01

...: R.A. Jervey, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001, telephone: (301) 251...'' series. This series was developed to describe and make available to the public such information as.... Although a time limit is given, comments and suggestions in connection with items for inclusion in guides...

76 FR 82323 - Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-30

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0296] Design, Inspection, and Testing Criteria for Air... for public comment draft regulatory guide (DG), DG-1274, ``Design, Inspection, and Testing Criteria... Systems in Light-Water-Cooled Nuclear Power Plants.'' This guide applies to the design, inspection, and...

76 FR 30280 - Public Meeting To Discuss the Proposed Rule on Enhanced Weapons, Firearms Background Checks, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-25

... Proposed Rule on Enhanced Weapons, Firearms Background Checks, and Security Event Notifications AGENCY... the proposed enhanced weapons rule, the two draft regulatory guides, and the draft weapons safety.... No formal comments on the proposed enhanced weapons rule or the draft guidance documents will be...

77 FR 14047 - Guidance for Decommissioning Planning During Operations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

...)-4014, ``Decommissioning Planning During Operations.'' This action is necessary to correct the NRC's... NUCLEAR REGULATORY COMMISSION [NRC-2011-0286] Guidance for Decommissioning Planning During Operations AGENCY: Nuclear Regulatory Commission. ACTION: Draft regulatory guide; correction. SUMMARY: The U...

75 FR 36445 - Draft Regulatory Guide, DG-4018, “Constraint on Releases of Airborne Radioactive Materials To the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-25

... Releases of Airborne Radioactive Materials To the Environment for Licensees Other Than Power Reactors... Regulatory Guide (DG)-4018, ``Constraint on Releases of Airborne Radioactive Materials to the Environment for..., ``Constraint on Releases of Airborne Radioactive Materials to the Environment for Licensees Other than Power...

77 FR 75198 - Standard Format and Content for Post-Shutdown Decommissioning Activities Report

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

...The U.S. Nuclear Regulatory Commission (NRC) is issuing for public comment draft regulatory guide (DG), DG-1272, ``Standard Format and Content for Post-shutdown Decommissioning Activities Report.'' This guide describes a method that the NRC staff considers acceptable for use in complying with the Commission's requirements regarding the submission of a post-shutdown decommissioning activities report (PSDAR).

77 FR 56239 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Regulatory...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... Draft Final Revision 1 to Regulatory Guide 1.163, ``Performance-Based Containment Leak-Test Program... inconvenience. If attending this meeting, please enter through the One White Flint North building, 11555...

77 FR 60478 - Control of Ferrite Content in Stainless Steel Weld Metal

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

...The U.S. Nuclear Regulatory Commission (NRC or the Commission) is issuing for public comment draft regulatory guide (DG), DG-1279, ``Control of Ferrite Content in Stainless Steel Weld Metal.'' This guide describes a method that the NRC staff considers acceptable for controlling ferrite content in stainless steel weld metal. Revision 4 updates the guide to remove references to outdated standards and to remove an appendix that has been incorporated into relevant specifications.

76 FR 50274 - Terrestrial Environmental Studies for Nuclear Power Stations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-12

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0182] Terrestrial Environmental Studies for Nuclear Power... draft regulatory guide (DG), DG-4016, ``Terrestrial Environmental Studies for Nuclear Power Stations... environmental studies and analyses supporting licensing decisions for nuclear power reactors. DATES: Submit...

75 FR 29785 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-27

... Guide, DG-1248, ``Nuclear Power Plant Simulation Facilities for Use in Operator Training, License..., ``Nuclear Power Plant Simulation Facilities for Use in Operator Training, License Examinations, and... or acceptance of a nuclear power plant simulation facility for use in operator and senior operator...

76 FR 77431 - Decommissioning Planning During Operations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

... (DG) DG-4014, ``Decommissioning Planning During Operations.'' This guide describes a method that the.... The draft regulatory guide entitled, ``Decommissioning Planning During Operations,'' is temporarily..., 40, 50, 70, and 72 RIN 3150-AI55 [NRC-2011-0286; NRC-2008-0030] Decommissioning Planning During...

76 FR 2425 - Draft Regulatory Guide: Reissuance and Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-13

... posted on the NRC website and on the Federal rulemaking website Regulations.gov . Because your comments... publicly disclosed. Federal Rulemaking Website: Go to http://www.regulations.gov and search for [email protected] . The Regulatory Analysis is available electronically under ADAMS Accession Number...

75 FR 13599 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-22

... Guide, DG-8040, ``Health Physics Surveys During Enriched Uranium-235 Processing and Fuel Fabrication... it deal specifically with the following aspects of an acceptable occupational health physics program that are closely related to surveys: (1) The number and qualification of the health physics staff, (2...

75 FR 58444 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-24

... Guide, DG-1244, ``Availability of Electric Power Sources.'' FOR FURTHER INFORMATION CONTACT: Satish..., ``Availability of Electric Power Sources'' temporarily identified by its task number, DG- 1244, which should be... Commission (NRC) considers acceptable when the available electric power sources are less than the number of...

76 FR 65753 - Monitoring the Effectiveness of Maintenance at Nuclear Power Plants

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-24

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0212] Monitoring the Effectiveness of Maintenance at...) re-issued Draft Regulatory Guide, DG-1278, ``Monitoring the Effectiveness of Maintenance at Nuclear... Revision 4A to Nuclear Management and Resources Council (NUMARC) 93-01, ``Industry Guideline for Monitoring...

77 FR 15812 - Initial Test Program of Condensate and Feedwater Systems for Light-Water Reactors

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-16

... comments received on or before this date. Although a time limit is given, comments and suggestions in... guides are encouraged at any time. ADDRESSES: You may access information and comment submissions related... Information The NRC is issuing for public comment a draft guide in the NRC's ``Regulatory Guide'' series. This...

75 FR 62610 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Plant...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

...: Draft Regulatory Guide DG-1237, ``Guidance on Making Changes to Emergency Plans for Nuclear Power Reactors,'' Interim Staff Guidance (ISG) NSIR/DPR-ISG-01, ``Emergency Planning for Nuclear Power Plants... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS...

77 FR 50720 - Test Documentation for Digital Computer Software Used in Safety Systems of Nuclear Power Plants

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-22

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0195] Test Documentation for Digital Computer Software...) is issuing for public comment draft regulatory guide (DG), DG-1207, ``Test Documentation for Digital... practices for test documentation for software and computer systems as described in the Institute of...

76 FR 44049 - Guidance for Fuel Cycle Facility Change Processes

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-22

... NUCLEAR REGULATORY COMMISSION [NRC-2009-0262] Guidance for Fuel Cycle Facility Change Processes...-issued Draft Regulatory Guide, DG- 3037, ``Guidance for Fuel Cycle Facility Change Processes'' in the...-3037 from August 12, 2011 to September 16, 2011. DG-3037 describes the types of changes for fuel cycle...

77 FR 36014 - Initial Test Program of Emergency Core Cooling Systems for Boiling-Water Reactors

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0134] Initial Test Program of Emergency Core Cooling... for public comment draft regulatory guide (DG), DG-1277, ``Initial Test Program of Emergency Core... acceptable to implement with regard to initial testing features of emergency core cooling systems (ECCSs) for...

76 FR 59448 - Draft Regulatory Guide; Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-26

... consideration only for comments received on or before this date. Although a time limit is given, comments and... published guides are encouraged at any time. ADDRESSES: Please include Docket ID NRC-2011-0224 in the... document using the following methods: NRC's Public Document Room (PDR): The public may examine and have...

75 FR 54918 - Draft Regulatory Guide, DG-1247, “Design-Basis Hurricane and Hurricane Missiles for Nuclear Power...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-09

... that the staff uses in evaluating specific problems or postulated accidents, and data that the staff... turbine missiles. NUREG/CR 7004 is the technical basis for regulatory guidance on design-basis hurricane... hurricane wind speeds for new nuclear power plants. [[Page 54919

77 FR 50722 - Software Unit Testing for Digital Computer Software Used in Safety Systems of Nuclear Power Plants

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-22

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0195] Software Unit Testing for Digital Computer Software...) is issuing for public comment draft regulatory guide (DG), DG-1208, ``Software Unit Testing for Digital Computer Software used in Safety Systems of Nuclear Power Plants.'' The DG-1208 is proposed...

78 FR 55117 - Ultimate Heat Sink for Nuclear Power Plants; Draft Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-09

... applicants may use to implement general design criteria (GDC) that are applicable to the ultimate heat sink... only for comments received on or before this date. Although a time limit is given, comments and... published guides are encouraged at any time. ADDRESSES: You may submit comment by any of the following...

76 FR 5215 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-28

... Compliance with Packaging Requirements for Shipment and Receipt of Radioactive Material,'' is temporarily... Code of Federal Regulations, Part 71, ``Packaging and Transportation of Radioactive Material'' (10 CFR... Compliance with Packaging Requirements for Shipments of Radioactive Materials,'' as an acceptable process for...

75 FR 62893 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-13

... for using portland cement grout to protect prestressing steel from corrosion. The prestressing tendon system of a prestressed concrete containment structure is a principal strength element of the structure... of the structure depends on the functional reliability of the structure's principal strength elements...

75 FR 33853 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-15

... performance or condition of structures, systems, or components * * * in a manner sufficient to provide reasonable assurance that these structures, systems, and components * * * are capable of fulfilling their... Management System (ADAMS). Comments would be most helpful if received by August 13, 2010. Comments received...

76 FR 59173 - Standard Format and Content of License Applications for Conventional Uranium Mills

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-23

...On May 30, 2008 (73 FR 31152), the U.S. Nuclear Regulatory Commission (NRC) published for public comment a notice of issuance and availability of Draft Regulatory Guide (DG)-3024, ``Standard Format and Content of License Applications for Conventional Uranium Mills.'' DG- 3024 was a proposed Revision 2 of Regulatory Guide (RG) 3.5. However, upon further consideration the NRC has decided not to revise RG 3.5 at this time. For this reason, DG-3024 will be withdrawn. The comment period closed on August 4, 2008, and 6 comments were received. The comments received will be considered and incorporated as appropriate if the NRC decides to revise RG 3.5 in the future.

75 FR 36698 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-28

... information based on the likelihood of pipe breaks of different sizes. The rule would divide all coolant... to and including a ``transition break size,'' and breaks larger than the transition size up to the largest pipe in the reactor coolant system. Selection of the transition size was based upon pipe break...

75 FR 28074 - Advisory Committee on Reactor Safeguards

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-19

..., 2009, (74 FR 52829-52830). Wednesday, June 9, 2010, Conference Room T2-B1, Two White Flint North... Regulatory Guide (RG) 1.216, ``Containment Structural Integrity Evaluation for Internal Pressure Loadings... representatives of the NRC staff regarding draft final RG 1.216, ``Containment Structural Integrity Evaluation for...

75 FR 41241 - Draft Regulatory Guide; Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-15

...: (301) 251-7404 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The U.S... analysis and testing applicable to Emergency Core Cooling System (ECCS) strainer performance and debris... provides text and image files of NRC's public documents. If you do not have access to ADAMS or if there are...

76 FR 4390 - Draft Regulatory Guide: Comment Period Extension and Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-25

....'' This Federal Register notice stated that electronic copies of DG-1229 were available in the NRC's Agencywide Documents Access and Management System (ADAMS) ( http://www.nrc.gov/reading-rm/adams.html ), under... Documents Access and Management System (ADAMS): Publicly available documents created or received at the NRC...

75 FR 5630 - Draft Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-03

... specific parts of the NRC's regulations, techniques that the staff uses in evaluating specific problems or postulated accidents, and data that the staff needs in its review of applications for permits and licenses... in license applications and for monitoring and reporting effluent data by licensees. The guidance is...

75 FR 61321 - Domestic Licensing of Production and Utilization Facilities; Updates to Incorporation by...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-05

... electronic reading room at http://www.nrc.gov/reading-rm/adams.html . From this page, the public can gain... Regulatory Guides dated April 2009. The NRC's electronic reading room contains later versions of these Draft... in the training provided to examiners. Computer-based training, through the use of animations...

76 FR 27924 - Draft Regulatory Guide, Guidance for ITAAC Closure

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-13

... received on or before this date. Although a time limit is given, comments and suggestions in connection... are encouraged at any time. ADDRESSES: Please include Docket ID NRC-2011-0102 in the subject line of... comments to: RADB at 301-492-3446. You can access publicly available documents related to this notice using...

76 FR 41527 - Draft Regulatory Guide: Re-Issuance and Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-14

... and methods that are acceptable to the NRC staff for implementing specific parts of the NRC's..., and fabrication of mixed-oxide fuel or fuel assemblies. DG-3037 provides guidance on how to meet the... publicly disclosed. You may submit comments by any one of the following methods: Federal Rulemaking Web...

Drafting Fundamentals. Drafting Module 1. Instructor's Guide.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This Missouri Vocational Instruction Management System instructor's drafting guide has been keyed to the drafting competency profile developed by state industry and education professionals. The guide contains a cross-reference table of instructional materials. Ten units cover drafting fundamentals: (1) introduction to drafting; (2) general safety;…

77 FR 70484 - Preoperational Testing of Onsite Electric Power Systems To Verify Proper Load Group Assignments...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-26

... publicly available documents online in the NRC Library at http://www.nrc.gov/reading-rm/adams.html . To... reproduce them. NRC's PDR: You may examine and purchase copies of public documents at the NRC's PDR, Room O1... that the staff needs in its review of applications for permits and licenses. The draft regulatory guide...

76 FR 10908 - Draft Guidance for Industry on Medication Guides-Distribution Requirements and Inclusion of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-28

...] Draft Guidance for Industry on Medication Guides--Distribution Requirements and Inclusion of Medication... a draft guidance for industry entitled ``Medication Guides--Distribution Requirements and Inclusion... Inclusion of Medication Guides in Risk Evaluation and Mitigation Strategies (REMS).'' This draft guidance is...

Computer Assisted Drafting (CNC) Drawings. Drafting Module 6. Instructor's Guide.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This Missouri Vocational Instruction Management System instructor's drafting guide has been keyed to the drafting competency profile developed by state industry and education professionals. This unit contains information on computer-assisted drafting drawings. The guide contains a cross-reference table of instructional materials and 20 worksheets.…

78 FR 66940 - Regulatory Requirements for Hearing Aid Devices and Personal Sound Amplification Products; Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-D-1295] Regulatory Requirements for Hearing Aid Devices and Personal Sound Amplification Products; Draft Guidance for... draft guidance entitled ``Regulatory Requirements for Hearing Aid Devices and Personal Sound...

Mechnical Drawing/Drafting Curriculum Guide.

ERIC Educational Resources Information Center

Gregory, Margaret R.; Benson, Robert T.

This curriculum guide consists of materials for teaching a course in mechanical drawing and drafting. Addressed in the individual units of the guide are the following topics: the nature and scope of drawing and drafting, visualization and spatial relationships, drafting tools and materials, linework, freehand lettering, geometric construction,…

Articulated Instruction Objectives Guide for Drafting. Final Document for Articulation of Drafting.

ERIC Educational Resources Information Center

Henderson, Wm. Edward, Jr.

Intended for use in competency-based and criterion-referenced vocational programs, this articulated, performance-based instruction objectives guide for Drafting I is designed for reference use in the articulation of drafting programs at the secondary and postsecondary levels. It consists of a description of the development of the guide, 14…

Curriculum Guide for Drafting Communication in Technology Education.

ERIC Educational Resources Information Center

Connecticut Industrial Technology Association.

Consistent with the principles of the Connecticut Common Core of Learning, this competency-based curriculum guide for drafting provides a reference guide for educators to research and prepare for teaching the field of drafting communications. The guide contains 44 units in three levels. The introductory level covers the following topics:…

40 CFR 124.204 - What must I do as the Director of the regulatory agency to prepare a draft standardized permit?

Code of Federal Regulations, 2011 CFR

2011-07-01

... regulatory agency to prepare a draft standardized permit? 124.204 Section 124.204 Protection of Environment... agency to prepare a draft standardized permit? (a) You must review the Notice of Intent and supporting... protection of human health and the environment. (c) You must prepare your draft permit decision within 120...

40 CFR 124.204 - What must I do as the Director of the regulatory agency to prepare a draft standardized permit?

Code of Federal Regulations, 2014 CFR

2014-07-01

... regulatory agency to prepare a draft standardized permit? 124.204 Section 124.204 Protection of Environment... agency to prepare a draft standardized permit? (a) You must review the Notice of Intent and supporting... protection of human health and the environment. (c) You must prepare your draft permit decision within 120...

40 CFR 124.204 - What must I do as the Director of the regulatory agency to prepare a draft standardized permit?

Code of Federal Regulations, 2012 CFR

2012-07-01

... regulatory agency to prepare a draft standardized permit? 124.204 Section 124.204 Protection of Environment... agency to prepare a draft standardized permit? (a) You must review the Notice of Intent and supporting... protection of human health and the environment. (c) You must prepare your draft permit decision within 120...

40 CFR 124.204 - What must I do as the Director of the regulatory agency to prepare a draft standardized permit?

Code of Federal Regulations, 2013 CFR

2013-07-01

... regulatory agency to prepare a draft standardized permit? 124.204 Section 124.204 Protection of Environment... agency to prepare a draft standardized permit? (a) You must review the Notice of Intent and supporting... protection of human health and the environment. (c) You must prepare your draft permit decision within 120...

40 CFR 124.204 - What must I do as the Director of the regulatory agency to prepare a draft standardized permit?

Code of Federal Regulations, 2010 CFR

2010-07-01

... regulatory agency to prepare a draft standardized permit? 124.204 Section 124.204 Protection of Environment... agency to prepare a draft standardized permit? (a) You must review the Notice of Intent and supporting... protection of human health and the environment. (c) You must prepare your draft permit decision within 120...

77 FR 64562 - Draft Emergency Preparedness Frequently Asked Questions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-22

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0248] Draft Emergency Preparedness Frequently Asked... Nuclear Regulatory Commission. Mark Thaggard, Deputy Director for Emergency Preparedness, Division of... comment. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC) is making available for comment Emergency...

76 FR 57767 - Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-16

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0204] Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for Operating Reactors AGENCY: Nuclear Regulatory Commission... FR 54507), that requested public comment on Draft NRC Generic Letter 2011- XX: Seismic Risk...

76 FR 70768 - Common-Cause Failure Analysis in Event and Condition Assessment: Guidance and Research, Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-15

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0254] Common-Cause Failure Analysis in Event and Condition Assessment: Guidance and Research, Draft Report for Comment; Correction AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG; request for comment; correction. SUMMARY: This document corrects a notice appearing...

76 FR 58311 - Draft License Renewal Interim Staff Guidance LR-ISG-2011-05; Ongoing Review of Operating Experience

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-20

... nuclear power plants. In response to a request from the Nuclear Energy Institute (NEI), the NRC is... NUCLEAR REGULATORY COMMISSION [NRC-2011-0191] Draft License Renewal Interim Staff Guidance LR-ISG-2011-05; Ongoing Review of Operating Experience AGENCY: Nuclear Regulatory Commission. ACTION: Draft...

Comparative Genomics as a Foundation for Evo-Devo Studies in Birds.

PubMed

Grayson, Phil; Sin, Simon Y W; Sackton, Timothy B; Edwards, Scott V

2017-01-01

Developmental genomics is a rapidly growing field, and high-quality genomes are a useful foundation for comparative developmental studies. A high-quality genome forms an essential reference onto which the data from numerous assays and experiments, including ChIP-seq, ATAC-seq, and RNA-seq, can be mapped. A genome also streamlines and simplifies the development of primers used to amplify putative regulatory regions for enhancer screens, cDNA probes for in situ hybridization, microRNAs (miRNAs) or short hairpin RNAs (shRNA) for RNA interference (RNAi) knockdowns, mRNAs for misexpression studies, and even guide RNAs (gRNAs) for CRISPR knockouts. Finally, much can be gleaned from comparative genomics alone, including the identification of highly conserved putative regulatory regions. This chapter provides an overview of laboratory and bioinformatics protocols for DNA extraction, library preparation, library quantification, and genome assembly, from fresh or frozen tissue to a draft avian genome. Generating a high-quality draft genome can provide a developmental research group with excellent resources for their study organism, opening the doors to many additional assays and experiments.

78 FR 75579 - License Renewal Application for Grand Gulf Nuclear Station, Unit 1

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-12

... NUCLEAR REGULATORY COMMISSION [Docket No. 50-416; NRC-2011-0262] License Renewal Application for Grand Gulf Nuclear Station, Unit 1 AGENCY: Nuclear Regulatory Commission. ACTION: Draft supplemental....S. Nuclear Regulatory Commission (NRC) is issuing for public comment a draft, plant-specific...

76 FR 61402 - Draft Nuclear Regulatory Commission Fiscal Year 2012-2016 Strategic Plan

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-04

... waste. The draft Strategic Plan also describes the agency's Organizational Excellence Objectives of Openness, Regulatory Effectiveness, and Operational Excellence, which characterize the manner in which the...

76 FR 50500 - Request for Comments on the Draft Policy Statement on Volume Reduction and Low-Level Radioactive...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-15

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0183] Request for Comments on the Draft Policy Statement on Volume Reduction and Low-Level Radioactive Waste Management AGENCY: Nuclear Regulatory Commission. ACTION: Request for public comment. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC) is revising its...

75 FR 39577 - Draft Supplemental Environmental Impact Statement on the Issuance of Annual Regulations...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-09

... timing of the general regulatory process. (2) Frequency of review and adoption of duck regulatory packages. Duck regulatory packages are the set of framework regulations that apply to the general duck... limits), and closed. In the draft SEIS, we present two alternatives regarding how frequently duck...

A State Articulated Instructional Objectives Guide for Occupational Education Programs. State Pilot Model for Drafting (Graphic Communications). Part I--Basic. Part II--Specialty Programs. Section A (Mechanical Drafting and Design). Section B (Architectural Drafting and Design).

ERIC Educational Resources Information Center

North Carolina State Dept. of Community Colleges, Raleigh.

A two-part articulation instructional objective guide for drafting (graphic communications) is provided. Part I contains summary information on seven blocks (courses) of instruction. They are as follow: introduction; basic technical drafting; problem solving in graphics; reproduction processes; freehand drawing and sketching; graphics composition;…

Drug interactions evaluation: An integrated part of risk assessment of therapeutics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Lei; Reynolds, Kellie S.; Zhao, Ping

2010-03-01

Pharmacokinetic drug interactions can lead to serious adverse events or decreased drug efficacy. The evaluation of a new molecular entity's (NME's) drug-drug interaction potential is an integral part of risk assessment during drug development and regulatory review. Alteration of activities of enzymes or transporters involved in the absorption, distribution, metabolism, or excretion of a new molecular entity by concomitant drugs may alter drug exposure, which can impact response (safety or efficacy). The recent Food and Drug Administration (FDA) draft drug interaction guidance ( (http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm072101.pdf)) highlights the methodologies and criteria that may be used to guide drug interaction evaluation by industrymore » and regulatory agencies and to construct informative labeling for health practitioner and patients. In addition, the Food and Drug Administration established a 'Drug Development and Drug Interactions' website to provide up-to-date information regarding evaluation of drug interactions ( (http://www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/DrugInteractionsLabeling/ucm080499.htm)). This review summarizes key elements in the FDA drug interaction guidance and new scientific developments that can guide the evaluation of drug-drug interactions during the drug development process.« less

78 FR 33862 - Draft Emergency Preparedness Frequently Asked Questions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0113] Draft Emergency Preparedness Frequently Asked... Commission. William Gott, Acting Deputy Director for Emergency Preparedness, Division of Preparedness and... comment. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC) is making available for comment Emergency...

10 CFR 51.71 - Draft environmental impact statement-contents.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Draft environmental impact statement-contents. 51.71 Section 51.71 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations...

[Task sharing with radiotherapy technicians in image-guided radiotherapy].

PubMed

Diaz, O; Lorchel, F; Revault, C; Mornex, F

2013-10-01

The development of accelerators with on-board imaging systems now allows better target volumes reset at the time of irradiation (image-guided radiotherapy [IGRT]). However, these technological advances in the control of repositioning led to a multiplication of tasks for each actor in radiotherapy and increase the time available for the treatment, whether for radiotherapy technicians or radiation oncologists. As there is currently no explicit regulatory framework governing the use of IGRT, some institutional experiments show that a transfer is possible between radiation oncologists and radiotherapy technicians for on-line verification of image positioning. Initial training for every technical and drafting procedures within institutions will improve audit quality by reducing interindividual variability. Copyright © 2013. Published by Elsevier SAS.

Articulated, Performance-Based Instruction Guide for Drafting II. Final Document. Revised.

ERIC Educational Resources Information Center

Henderson, William Edward, Jr.

Developed during a project designed to provide continuous, performance-based vocational training at the secondary and postsecondary levels, this instructional guide is intended to help teachers implement a laterally and vertically articulated secondary level drafting II program. Introductory materials include a description of Drafting II,…

Computer Aided Drafting. Instructor's Guide.

ERIC Educational Resources Information Center

Henry, Michael A.

This guide is intended for use in introducing students to the operation and applications of computer-aided drafting (CAD) systems. The following topics are covered in the individual lessons: understanding CAD (CAD versus traditional manual drafting and care of software and hardware); using the components of a CAD system (primary and other input…

78 FR 52570 - Draft Emergency Preparedness Frequently Asked Questions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-23

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0197] Draft Emergency Preparedness Frequently Asked... comment. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC) is making available for comment Emergency Preparedness (EP) frequently asked questions (EPFAQs) No. 2013-004, No. 2013-006, and No. 2013-007. These...

75 FR 6064 - Draft Emergency Action Level Frequently Asked Questions; Request for Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-05

... provide clarification of endorsed Nuclear Energy Institute (NEI) guidance related to the development of... NUCLEAR REGULATORY COMMISSION [NRC-2010-0034] Draft Emergency Action Level Frequently Asked Questions; Request for Comment AGENCY: Nuclear Regulatory Commission. ACTION: Notice of availability and...

Drafting Lab Management Guide.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. Instructional Materials Lab.

This manual was developed to guide drafting instructors and vocational supervisors in sequencing laboratory instruction and controlling the flow of work for a 2-year machine trades training program. The first part of the guide provides information on program management (program description, safety concerns, academic issues, implementation…

Advanced Technical Drafting (Industrial Arts) Curriculum Guide. Bulletin 1751.

ERIC Educational Resources Information Center

Louisiana State Dept. of Education, Baton Rouge. Div. of Vocational Education.

This curriculum guide contains materials for a 17-unit course in advanced technical drafting, a followup to the basic technical drafting course in the industrial arts curriculum for grades 10-12. It is intended for use by industrial arts teachers, supervisors, counselors, administrators, and teacher educators. A three-page course overview provides…

Computer-Aided Drafting. Education for Technology Employment.

ERIC Educational Resources Information Center

Northern Illinois Univ., De Kalb. Dept. of Technology.

This computer-aided drafting (CAD) curriculum was developed to provide drafting instructors in Illinois with a useful guide for relating an important new technological advance to the vocational classroom. The competency-based learning activity guides are written to be used with any CAD system being used at the secondary and postsecondary levels.…

Introduction to Production/Manufacturing Drafting. Drafting Module 8. Instructor's Guide.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This module, 1 of 10 in the Drafting curriculum guide developed in Missouri, contains 3 units of study that include some or all of the following components: performance objectives, lesson plans, information sheets, transparency masters, handouts, assignment sheets, job sheets, a unit test, and answers to the unit test. Special instructions on…

77 FR 16270 - Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0070] Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft..., ``Updated Aging Management Criteria for PWR Reactor Vessel Internal Components.'' This draft LR-ISG revises...

75 FR 47856 - Draft Emergency Action Level Frequently Asked Questions; Request for Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-09

... provide clarification of guidance submitted by the Nuclear Energy Institute (NEI) and endorsed by the NRC... NUCLEAR REGULATORY COMMISSION [NRC-2010-0273] Draft Emergency Action Level Frequently Asked Questions; Request for Comment AGENCY: Nuclear Regulatory Commission. ACTION: Notice of availability and...

10 CFR 51.85 - Draft environmental impact statement-rulemaking.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Draft environmental impact statement-rulemaking. 51.85 Section 51.85 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR... Implementing Section 102(2) Draft Environmental Impact Statements-Rulemaking § 51.85 Draft environmental impact...

10 CFR 51.85 - Draft environmental impact statement-rulemaking.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Draft environmental impact statement-rulemaking. 51.85 Section 51.85 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR... Implementing Section 102(2) Draft Environmental Impact Statements-Rulemaking § 51.85 Draft environmental impact...

10 CFR 51.85 - Draft environmental impact statement-rulemaking.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Draft environmental impact statement-rulemaking. 51.85 Section 51.85 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR... Implementing Section 102(2) Draft Environmental Impact Statements-Rulemaking § 51.85 Draft environmental impact...

10 CFR 51.85 - Draft environmental impact statement-rulemaking.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Draft environmental impact statement-rulemaking. 51.85 Section 51.85 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR... Implementing Section 102(2) Draft Environmental Impact Statements-Rulemaking § 51.85 Draft environmental impact...

General Mission Analysis Tool (GMAT) User's Guide (Draft)

NASA Technical Reports Server (NTRS)

Hughes, Steven P.

2007-01-01

4The General Mission Analysis Tool (GMAT) is a space trajectory optimization and mission analysis system. This document is a draft of the users guide for the tool. Included in the guide is information about Configuring Objects/Resources, Object Fields: Quick Look-up Tables, and Commands and Events.

Mechanical Drafting. Student Learning Guides.

ERIC Educational Resources Information Center

Ridge Vocational-Technical Center, Winter Haven, FL.

These four learning guides are self-instructional packets for four tasks identified as essential for performance on an entry-level job in mechanical drafting. Each guide is based on a terminal performance objective (task) and 2-4 enabling objectives. For each enabling objective, some or all of these materials may be presented: learning steps…

76 FR 69294 - Proposed Generic Communication Draft Generic Letter on Seismic Risk Evaluations for Operating...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-08

.... Nuclear Regulatory Commission (NRC) published for public comment Draft Generic Letter 2011-XX: Seismic... comment Draft Generic Letter 2011-XX: Seismic Risk Evaluations for Operating Reactors to inform addressees...

77 FR 60418 - Town of Stuyvesant, New York and Albany Engineering Corporation; Notice of Availability of Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2696-033-NY] Town of Stuyvesant, New York and Albany Engineering Corporation; Notice of Availability of Draft Environmental Assessment In accordance with the National Environmental Policy Act of 1969 and the Federal Energy Regulatory...

75 FR 5355 - Notice of Extension of Comment Period for NUREG-1934, Nuclear Power Plant Fire Modeling...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-02

..., Nuclear Power Plant Fire Modeling Application Guide (NPP FIRE MAG), Draft Report for Comment AGENCY... 1019195), Nuclear Power Plant Fire Modeling Application Guide (NPP FIRE MAG), Draft Report for Comment... Plant Fire Modeling Application Guide (NPP FIRE MAG)'' is available electronically under ADAMS Accession...

76 FR 77855 - Detroit Edison Company; Notice of Availability of Errata Sheet for the Draft Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-14

... NUCLEAR REGULATORY COMMISSION [Docket No. 52-033; NRC-2008-0566] Detroit Edison Company; Notice of Availability of Errata Sheet for the Draft Environmental Impact Statement for a Combined License for Unit 3 at the Enrico Fermi Atomic Power Plant Site Notice is hereby given that the U.S. Nuclear Regulatory...

76 FR 66998 - Detroit Edison Company; Notice of Availability of Draft Environmental Impact Statement for a...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-28

... NUCLEAR REGULATORY COMMISSION [Docket No. 52-033; NRC-2008-0566] Detroit Edison Company; Notice of Availability of Draft Environmental Impact Statement for a Combined License for Unit 3 at the Enrico Fermi Atomic Power Plant Site Notice is hereby given that the U.S. Nuclear Regulatory Commission (NRC) [[Page...

75 FR 12230 - Idaho Power Company, Idaho; Notice of Availability of Draft Environmental Impact Statement for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-15

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 503-048] Idaho Power Company, Idaho; Notice of Availability of Draft Environmental Impact Statement for the Swan Falls Project March 5, 2010. In accordance with the National Environmental Policy Act of 1969 and the Federal Energy Regulatory Commission's (Commission or FERC's)...

75 FR 29588 - Office of New Reactors: Proposed NUREG-0800; Standard Review Plan Section 13.6.6, Draft Revision...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-26

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0184] Office of New Reactors: Proposed NUREG-0800; Standard Review Plan Section 13.6.6, Draft Revision 0 on Cyber Security Plan AGENCY: Nuclear Regulatory... Plants,'' on a proposed Standard Review Plan (SRP) Section 13.6.6 on ``Cyber Security Plan'' (Agencywide...

Turf and Lawn Management: A Course in Agricultural Education. Curriculum Guide. Preliminary Draft.

ERIC Educational Resources Information Center

Mercer, R. J., Ed.

The curriculum guide (preliminary draft) is a result of the revision of the total South Carolina agricultural education curriculum; the scope of the turf and lawn management industry and its direct and indirect employment opportunities provide ample reasons for such a course offering in South Carolina high schools. The guide presents objectives,…

77 FR 33489 - Draft Offender Tracking System Standard

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-06

... Tracking System Standard AGENCY: National Institute of Justice. ACTION: Notice of Draft Offender Tracking System Standard, Selection and Application Guide, and Certification Program Requirements. SUMMARY: In an...) A draft standard entitled, ``Offender Tracking System Standard'' (2) a draft companion document...

Competency Reference for Computer Assisted Drafting.

ERIC Educational Resources Information Center

Oregon State Dept. of Education, Salem. Div. of Vocational Technical Education.

This guide, developed in Oregon, lists competencies essential for students in computer-assisted drafting (CAD). Competencies are organized in eight categories: computer hardware, file usage and manipulation, basic drafting techniques, mechanical drafting, specialty disciplines, three dimensional drawing/design, plotting/printing, and advanced CAD.…

Regulatory Forum Opinion Piece: Review of FDA Draft Guidance Testicular Toxicity-Evaluation during Drug Development Guidance for Industry.

PubMed

Hukkanen, Renee R; Halpern, Wendy G; Vidal, Justin D

2016-10-01

In July 2015, the U.S. Food and Drug Administration (FDA) posted a new draft guidance entitled "Testicular Toxicity: Evaluation during Drug Development Guidance for Industry," with a 90-day public comment period. As the nonclinical assessment of testicular toxicity often relies on the expert interpretation of pathology affecting the male reproductive tract, this draft guidance is considered directly relevant to the toxicologic pathology community. Therefore, a working group was formed through the Scientific and Regulatory Policy Committee of the Society of Toxicologic Pathologists (STPs) to provide a detailed review of the draft guidance. Specific comments on the guidance were submitted to the FDA by the STP. The draft guidance and all comments received are currently under review with the FDA. This commentary provides a summary of the components of the draft guidance and the comments submitted by the STP with acknowledgment of different perspectives reflected in comments from other respondents. © The Author(s) 2016.

18 CFR 5.25 - Applications requiring a draft NEPA document.

Code of Federal Regulations, 2010 CFR

2010-04-01

... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... include for comment draft license articles, a preliminary determination of the consistency of each fish...

18 CFR 5.25 - Applications requiring a draft NEPA document.

Code of Federal Regulations, 2011 CFR

2011-04-01

... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... include for comment draft license articles, a preliminary determination of the consistency of each fish...

Design/Drafting (Graphic Communications). Industrial Arts, Senior High--Level II. North Dakota Senior High Industrial Arts Curriculum Guides.

ERIC Educational Resources Information Center

Poehls, Eddie; And Others

This course guide for a design/drafting course is one of four developed for the graphic communications area in the North Dakota senior high industrial arts education program. (Eight other guides are available for two other areas of Industrial Arts--energy/power and production.) Part 1 provides such introductory information as a definition and…

CBT Pilot Program Instructional Guide. Basic Drafting Skills Curriculum Delivered through CAD Workstations and Artificial Intelligence Software.

ERIC Educational Resources Information Center

Smith, Richard J.; Sauer, Mardelle A.

This guide is intended to assist teachers in using computer-aided design (CAD) workstations and artificial intelligence software to teach basic drafting skills. The guide outlines a 7-unit shell program that may also be used as a generic authoring system capable of supporting computer-based training (CBT) in other subject areas. The first section…

18 CFR 5.24 - Applications not requiring a draft NEPA document.

Code of Federal Regulations, 2011 CFR

2011-04-01

... requiring a draft NEPA document. 5.24 Section 5.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... assessment issued pursuant to this paragraph must include draft license articles, a preliminary determination...

18 CFR 5.24 - Applications not requiring a draft NEPA document.

Code of Federal Regulations, 2010 CFR

2010-04-01

... requiring a draft NEPA document. 5.24 Section 5.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... assessment issued pursuant to this paragraph must include draft license articles, a preliminary determination...

78 FR 11654 - Draft Guidance for Industry and Food and Drug Administration Staff; Providing Information About...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-19

...] Draft Guidance for Industry and Food and Drug Administration Staff; Providing Information About... Guidance for Industry and Food and Drug Administration Staff: Providing Information About Pediatric Uses of...ComplianceRegulatoryInformation/default.htm . To receive ``Draft Guidance for Industry and Food and Drug...

78 FR 17943 - Draft Program-Specific Guidance About Fixed Gauge Licenses

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-25

... is requesting public comment on draft NUREG-1556, Volume 4, Revision 1, ``Consolidated Guidance About... sensitive information, and changes in regulatory policies and practices. This document is intended for use...-415- 4737, or by email to [email protected] . The draft NUREG-1556, Volume 4, Revision 1, is...

Mechanical Drafting Curriculum Guide. Michigan Trade and Industrial Education.

ERIC Educational Resources Information Center

Michigan State Univ., East Lansing. Coll. of Agriculture and Natural Resources Education Inst.

This task-based curriculum guide is intended to help secondary teachers provide relevant training for an entry-level job in mechanical drafting. Introductory materials include background information on trade and industrial education and program goals and safety information. Descriptions follow of the construction trades program, vocational…

Architectural Drafting: Commercial Applications. Teacher Guide.

ERIC Educational Resources Information Center

Whitney, Terry A.

This curriculum guide contains the technical information and tasks necessary for a student (who has already completed basic drafting) to be employed as an architectural drafter trainee. The curriculum is written in terms of student performance using measurable objectives, technical information, tasks developed to accomplish those objectives, and…

75 FR 45130 - Draft Compliance Policy Guide Sec. 690.800 Salmonella

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-02

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0378] Draft Compliance Policy Guide Sec. 690.800 Salmonella in Animal Feed; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the...

76 FR 52355 - NUREG-1482, Revision 2, “Guidelines for Inservice Testing at Nuclear Power Plants, Draft Report...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-22

... Testing at Nuclear Power Plants, Draft Report for Comment'' AGENCY: Nuclear Regulatory Commission. ACTION... Testing at Nuclear Power Plants, Draft Report for Comment,'' and subtitled ``Inservice Testing of Pumps and Valves, and Inservice Examination and Testing of Dynamic Restraints (Snubbers) at Nuclear Power...

77 FR 5281 - State-of-the-Art Reactor Consequence Analyses Reports

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-02

... Analyses Reports AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG; public meeting and request for... release of Draft NUREG-1935, ``State-of-the-Art Reactor Consequence Analyses (SOARCA) Report,'' for public comment. The purpose of Draft NUREG-1935 is to report a pilot study of best estimate analyses of the...

78 FR 38026 - Alabama Power, Inc.; Supplement to Notice of Availability of the Draft Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-25

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 349-173] Alabama Power, Inc.; Supplement to Notice of Availability of the Draft Environmental Impact Statement for the Martin Dam... Impact Statement (draft EIS) for the Martin Dam Hydroelectric Project No. 349- 173 (Martin Dam Project...

Orientation, Sketching, Mechanical Drawing, Drafting--Basic: 9253.01.

ERIC Educational Resources Information Center

Dade County Public Schools, Miami, FL.

The course introduces the student to the drafting trade, freehand sketching, and basic mechanical drawing. The course has no prerequisites and will guide the student into drafting concepts and serve as a foundation for further study in vocational drafting. Requiring a total of 45 class hours, eight hours are utilized in orientation, 15 hours are…

Compensatory Mitigation Rule Draft Environmental Assessment

EPA Pesticide Factsheets

Draft Compensatory Mitigation Rule intended to promote regulatory efficiency by establishing standards and criteria that would apply to compensatory mitigation required for DA permits issued under Section 404 of the Clean Water Act.

Industrial Arts Curriculum Guide in Basic Technical Drafting. Bulletin No. 1686.

ERIC Educational Resources Information Center

Louisiana State Dept. of Education, Baton Rouge. Div. of Vocational Education.

This curriculum guide contains operational guidelines to help local administrators, teacher educators, and industrial arts teachers in the State of Louisiana determine the extent to which their technical drafting courses are meeting the needs of the youth they serve. It consists of a discussion of course prerequisites, goals, content, and…

78 FR 20326 - Draft Compliance Policy Guide Sec. 100.250 Food Facility Registration-Human and Animal Food...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-04

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-D-0126] Draft Compliance Policy Guide Sec. 100.250 Food Facility Registration--Human and Animal Food; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug...

75 FR 66769 - Draft Compliance Policy Guide Sec. 690.800 Salmonella

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-29

...] Draft Compliance Policy Guide Sec. 690.800 Salmonella in Animal Feed; Availability; Extension of Comment... that are adulterated due to the presence of Salmonella. The Agency is taking this action in response to... action against animal feed or feed ingredients that are adulterated due to the presence of Salmonella...

75 FR 27838 - Notice of Availability of Draft NUREG-1800, Revision 2; “Standard Review Plan for Review of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-18

... Draft NUREG-1801, Revision 2; ``Generic Aging Lessons Learned (GALL) Report'' AGENCY: Nuclear Regulatory... Applications for Nuclear Power Plants ''and draft NUREG-1801, ``Generic Aging Lessons Learned (GALL) Report... Power Plants'' (SRP-LR); and the revised NUREG-1801, ``Generic Aging Lessons Learned (GALL) Report'' for...

A Guide for Planning Drafting and Design Technology Programs. Section III, Data Collection and Analysis.

ERIC Educational Resources Information Center

1971

This document, the second of three related reports, constitutes the data collection and analysis section of the study designed to provide information for preparing a planning guide for drafting and design technology programs. The curriculum survey instrument mailed to 26 schools, contained questions regarding: (1) length of semesters, (2)…

[European Blood Alliance (EBA) and EuroNet TMS: what challenges for the transfusion of tomorrow?].

PubMed

Folléa, G; de Wit, J; Rouger, P

2011-04-01

The primary mission of the European Blood Alliance (EBA) is to contribute to the safety and efficiency of the supply of blood products, cells and tissues, in developing an active network of blood establishments in Europe (25 countries). Its strategic objectives are to improve performance (through working groups and projects funded by the European Union), to engage in regulatory affairs (particularly at the European Commission level) to promote best practices and to facilitate a network to collect and share knowledge and experiences. The main objective of EuroNet TMS, combining the blood scientific societies from more than 30 countries in Europe, is to update and publish regularly, intended for policymakers, a White Book on the transfusion chain from donor to patient and probable or possible changes in the coming 5 years. Since 2008, EBA and EuroNet TMS actively collaborate on the drafting of the 2nd edition to be published in 2011. The two presidents jointly drafted the final chapter outlining the major issues of transfusion for tomorrow, summarized thereafter. Transfusion will still be useful for a long time and for reasons of safety and ethics the voluntary and unpaid donations, with non-profit blood establishments, will remain, the cornerstone of the supply of blood products. This renders crucial the continuous improvement of donor management and optimal blood use. On the regulatory side, after 5 years of implementation, EU directives must be independently evaluated and the Blood Guide of the Council of Europe should gradually become a regulatory standard. Finally, if a competition should be introduced for the blood products, it should be strictly regulated to prevent any threat to the security of their supply and quality for patients. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

Pipe Drafting with CAD. Teacher Edition.

ERIC Educational Resources Information Center

Smithson, Buddy

This teacher's guide contains nine units of instruction for a course on computer-assisted pipe drafting. The course covers the following topics: introduction to pipe drafting with CAD (computer-assisted design); flow diagrams; pipe and pipe components; valves; piping plans and elevations; isometrics; equipment fabrication drawings; piping design…

78 FR 72122 - Draft Emergency Preparedness Frequently Asked Questions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-02

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0262] Draft Emergency Preparedness Frequently Asked... of guidance documents related to the development and maintenance of emergency preparedness program... the interpretation or applicability of emergency preparedness guidance issued or endorsed by the NRC...

77 FR 25504 - Draft Emergency Preparedness Frequently Asked Questions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-30

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0098] Draft Emergency Preparedness Frequently Asked... comment Emergency Preparedness (EP) frequently asked questions (EPFAQs). These EPFAQs will be used to... Emergency Preparedness Frequently Asked Questions is available electronically under ADAMS Accession Number...

T & I--Drafting, Reading the Architect's Scale. Kit No. 16. Instructor's Manual [and] Student Learning Activity Guide.

ERIC Educational Resources Information Center

Jones, Philip

An instructor's manual and student activity guide on reading the architect's scale and the metric scale are provided in this set of prevocational education materials which focuses on the vocational area of trade and industry (drafting). (This set of materials is one of ninety-two prevocational education sets arranged around a cluster of seven…

Secondary School Curriculum Guide. Music, Grades 7-9. Draft Copy.

ERIC Educational Resources Information Center

Rogers, Arnold R., Ed.; And Others

This draft curriculum guide is for use in grades 7-9 and covers six levels of musical competence. The levels included for study in this 3 year program are: 1) general music, in which the student learns about rythm, tempo, and beat patterns, note and rest values, time signatures, and some musical terms; 2) musical forms, elements of music, score…

77 FR 66650 - Proposed Revisions to Radiation Protection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-06

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0268] Proposed Revisions to Radiation Protection AGENCY: Nuclear Regulatory Commission. ACTION: Standard review plan-draft section revision; request for comment. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC or the Commission) is revising the following sections...

Mountain Plains Learning Experience Guide: Drafting. Course: Basic Drawing. Revised Edition.

ERIC Educational Resources Information Center

Wetterling, C.; Wheatley, J.

One of two individualized courses included in a drafting curriculum, this course is designed to develop the fundamental skills of drafting using mechanical instruments. The course is comprised of thirteen units: (1) Mechanical Drawing, (2) Lettering, (3) Geometric Construction, (4) Shape Description, (5) Multiview Projection and Drawing…

78 FR 47410 - General Management Plan, Draft Environmental Impact Statement, Gateway National Recreation Area...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-05

...] General Management Plan, Draft Environmental Impact Statement, Gateway National Recreation Area, New... (NPS) is releasing a Draft Environmental Impact Statement (DEIS) for the General Management Plan (GMP... alternatives to guide the management of the site over the next 20 years. The NPS preferred alternative...

78 FR 53792 - Draft Guidance for Reciprocity

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-30

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0186] Draft Guidance for Reciprocity AGENCY: Nuclear... Commission (NRC) is revising its licensing guidance for reciprocity. The NRC is requesting public comment on... Work in Agreement State Jurisdiction (Reciprocity).'' The document has been updated from the previous...

Repair boundary for parent tube indications within the upper joint zone of hybrid expansion joint (HEJ) sleeved tubes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cullen, W.K.; Keating, R.F.

1997-02-01

In the Spring and Fall of 1994, and the Spring of 1995, crack-like indications were found in the upper hybrid expansion joint (HEJ) region of Steam Generator (S/G) tubes which had been sleeved using Westinghouse HEJ sleeves. As a result of these findings, analytic and test evaluations were performed to assess the effect of the degradation on the structural, and leakage, integrity of the sleeve/tube joint relative to the requirements of the United States Nuclear Regulatory Commission`s (NRC) draft Regulatory Guide (RG) 1.121. The results of these evaluations demonstrated that tubes with implied or known crack-like circumferential parent tube indicationsmore » (PTIs) located 1.1 inches or farther below the bottom of the hardroll upper transition, have sufficient, and significant, integrity relative to the requirements of RG 1.121. Thus, the purpose of this report is to provide background information related to the justification of the modified tube repair boundary.« less

DEVELOPMENT OF HFE SECTIONS OF DG-1145.

DOE Office of Scientific and Technical Information (OSTI.GOV)

HIGGINS,J.C.; OHARA, J.M.; BONGARRA, J.

2007-03-26

For the licensing of the current fleet of commercial nuclear power plants (NPPs), the Nuclear Regulatory Commission (NRC) used two key documents, NUREG-0800 and Regulatory Guide (RG) 1.70. RG 1.70 provided guidance to applicants on the contents needed in their Safety Analysis Reports (SARs) submitted as part of their application to construct or operate an NPP. NUREG-0800, the NRC Standard Review Plan (SRP), provides guidance to the NRR staff reviewers on performing their safety reviews of these applications. As part of the preparation for a new wave of improved NPP designs the NRC is in the process of updating themore » SRP and is also developing a new RG designated as draft RG or DG-1145, ''Combined License Applications for Nuclear Power Plants (LWR Edition).'' This will eventually become RG 1.206 and will take the place of RG 1.70. This will provide guidance for combined license (COL) applicants, as well as for other 10CFR Part 52 variations that are permitted.« less

Interpretation of aged sorption studies for pesticides and their use in European Union regulatory leaching assessments.

PubMed

Beulke, Sabine; van Beinum, Wendy; Suddaby, Laura

2015-04-01

First-tier regulatory exposure assessments for pesticides assume that pesticide sorption is instantaneous and fully reversible. In European Union (EU) regulatory guidance, an increase in sorption over time ("aged sorption") can be considered at the higher tier to refine predicted environmental concentrations in groundwater. Research commissioned by the UK Chemicals Regulation Directorate (CRD), funded by the Department for Environment Food & Rural Affairs (Defra), formed the basis of a draft regulatory guidance document proposing 1) a protocol on how to measure aged sorption of parent compounds in laboratory studies, 2) procedures to fit kinetic models to the experimental data, 3) criteria to test the reliability of the parameters, and 4) procedures for use of the parameters in the groundwater exposure assessment. The draft guidance was revised after feedback from stakeholders and testing of the guidance was performed against real data sets by an independent consultancy. The Chemicals Regulation Directorate submitted the revised document to the European Food Safety Authority (EFSA) for scrutiny. This article gives an overview of the draft guidance and explains the reasoning behind the recommendations made. 2015 Crown Copyright; Published 2015 SETAC.

76 FR 31507 - Domestic Licensing of Source Material-Amendments/Integrated Safety Analysis

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-01

... Licensing of Source Material--Amendments/Integrated Safety Analysis AGENCY: Nuclear Regulatory Commission... rule announced the availability of a draft regulatory analysis for public comment. This document... in Section XI, ``Regulatory Analysis.'' The correct ADAMS accession number is ML102380243. DATES: The...

Learning to Read and Write the Drafting Way. Field Test Copy.

ERIC Educational Resources Information Center

California State Dept. of Education, Sacramento. Div. of Vocational Education.

This volume comprises instructional techniques that are designed for use with drafting students who demonstrate a need for additional instruction in the areas of reading, writing, math, and verbal and visual communication. Included in the guide are the following teacher-developed instructional techniques: a drafting crossword puzzle, tool bingo, a…

78 FR 18674 - Invitation for Public Comment on Draft DOT Research, Development and Technology Strategic Plan...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-27

...-0002] Invitation for Public Comment on Draft DOT Research, Development and Technology Strategic Plan... for public comment on its draft strategic plan, U.S. Department of Transportation, Research, Development and Technology Strategic Plan FY 2013-2018. The new five-year strategic plan will guide the...

ICLUS Tools and Datasets (Version 1.2) and User's Manual: Arcgis Tools and Datasets for Modeling US Housing Density (External Review Draft)

EPA Science Inventory

This draft Geographic Information System (GIS) tool can be used to generate scenarios of housing-density changes and calculate impervious surface cover for the conterminous United States. A draft User’s Guide accompanies the tool. This product distributes the population project...

77 FR 58416 - Comparative Environmental Evaluation of Alternatives for Handling Low-Level Radioactive Waste...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-20

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0218] Comparative Environmental Evaluation of Alternatives... public comment the Draft Comparative Environmental Evaluation of Alternatives for Handling Low-Level.... Availability of Documents ADAMS Accession No. Document title ML12256A965 Draft Comparative Environmental...

10 CFR 51.71 - Draft environmental impact statement-contents.

Code of Federal Regulations, 2014 CFR

2014-01-01

... proposed action involving nuclear power reactors (e.g., alternative energy sources) is intended to assist... 10 Energy 2 2014-01-01 2014-01-01 false Draft environmental impact statement-contents. 51.71 Section 51.71 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR...

76 FR 63565 - Event Reporting Guidelines

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-13

...-2011-0237] Event Reporting Guidelines AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG... comments on Draft NUREG-1022, Revision 3, ``Event Reporting Guidelines: 10 CFR 50.72 and 50.73''. The NUREG-1022 contains guidelines that the NRC staff considers acceptable for use in meeting the event reporting...

Regulatory assessment of reproductive toxicology data.

PubMed

Davidson, Elizabeth

2013-01-01

This chapter outlines a regulator's personal approach to the assessment of reproductive toxicology data in the context of the assessment of the overall nonclinical data package for pharmaceutical agents. Using as a framework the International Conference on Harmonisation Common Technical Document headings, guidance is provided on the expectations of regulators for the presentation and discussion of the data by the applicant to facilitate the risk assessment process. Consideration is given to the use of reproductive toxicology data in the assessment process for both clinical trial applications (CTAs) and marketing authorization applications (MAAs). Suggestions for some guiding principles in drafting of the various product information documents (for example the Investigator's Brochure (IB) for CTAs and the Nonclinical Overview and Summary of Product Characteristics for MAAs) are included.

Implementation of 10 CFR 20.1406 Through Life Cycle Planning for Decommissioning

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Donnell, E.; Ott, W.R.

2008-01-15

The focus of this paper is on a regulatory guide (draft guide DG-4012) being developed by the Office of Nuclear Regulatory Research for the implementation of 10 CFR 20.1406. The draft guide was published in the Federal Register on July 31, 2007 for a 90 day public comment period. Besides being available in the Federal Register, it is also available electronically in NRC's agency data management system (ADAMS). The accession number is ML0712100110. 10 CFR 20.1406 requires license applicants, other than renewals, after August 20, 1997, '..to describe in the application how facility design and procedures for operation will minimize,more » to the extent practicable, contamination of the facility and the environment, facilitate eventual decommissioning, and minimize to the extent practicable, the generation of radioactive waste'. The intent of the regulation is to diminish the occurrence and severity of 'legacy sites' by taking measures that will reduce and control contamination and facilitate eventual decommissioning. 10 CFR 20.1406 is significant because it applies to all new facilities and in the very near future (perhaps as soon as the fall of 2007), the U.S. Nuclear Regulatory Commission (NRC) anticipates receiving one or more license applications for new nuclear power plants. The regulatory guide is intended to facilitate that licensing by providing suggestions of things an applicant can do to minimize contamination of the facility and the environment, minimize generation of waste, and to facilitate decommissioning. Over 100 different kinds of activities are covered by license applications submitted to the NRC. They do not all reflect the same potential for contamination of a facility and the environment, or for the generation of radioactive waste. Therefore, an applicant should use sound judgment to evaluate the potential for contamination and the consequences of such contamination in deciding on the extent to which this guide applies to any given facility or activity. Factors which may enter into this decision include form (e.g., dry solids, liquids, gases), inventory, and environmental mobility of unintended releases. The bulk of the guidance presented in the guide will consist of specific design considerations drawn from nuclear industry experience and lessons learned from decommissioning. These design suggestions provide examples of measures which can be combined to support a contaminant management philosophy for a new facility. The principles embodied in this philosophy are threefold: (1) prevention of unintended release, (2) early detection if there is unintended release of radioactive contamination, and (3) prompt and aggressive clean-up should there be an unintended release of radioactive contamination. If the guiding principles are followed through the use of 'good' engineering and science, as well as careful attention to operational practices, it should result in meeting the requirements of 10 CFR 20.1406. All this should be considered in the context of the life cycle of the facility from the early planning stages through the final plans for decommissioning and waste disposal. Some of the mechanisms which can be employed for life cycle planning are described further in the Discussion section. In summary: The principles of the guide are threefold: prevention, early detection, and prompt response. If these guiding principles are followed through the use of 'good' engineering and science, as well as careful attention to operational practices, it should result in meeting the requirements of 10 CFR 20 In summary, the thrust of this guide is for an applicant to use technically sound engineering judgment and a practical risk-informed approach to achieve the objectives of 10 CFR 20.1406. This approach should consider the materials and processes involved (e.g., solids, liquids, gases) and focus on: (1) the relative significance of potential contamination; (2) areas most susceptible to leaks; and (3) the appropriate level of consideration to prevention and control of contamination that should be incorporated in facility design. Since the applicability of the guidance is a facility-by-facility decision, early consultation with the NRC is strongly suggested.« less

77 FR 24722 - Draft Guidance for Industry: Assessing the Effects of Significant Manufacturing Process Changes...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-25

...] Draft Guidance for Industry: Assessing the Effects of Significant Manufacturing Process Changes... Substances, Including Food Ingredients That Are Color Additives; Availability AGENCY: Food and Drug... Manufacturing Process Changes, Including Emerging Technologies, on the Safety and Regulatory Status of Food...

10 CFR 51.71 - Draft environmental impact statement-contents.

Code of Federal Regulations, 2013 CFR

2013-01-01

... involving nuclear power reactors (e.g., alternative energy sources) is intended to assist the NRC in meeting... 10 Energy 2 2013-01-01 2013-01-01 false Draft environmental impact statement-contents. 51.71 Section 51.71 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR...

10 CFR 51.71 - Draft environmental impact statement-contents.

Code of Federal Regulations, 2012 CFR

2012-01-01

... involving nuclear power reactors (e.g., alternative energy sources) is intended to assist the NRC in meeting... 10 Energy 2 2012-01-01 2012-01-01 false Draft environmental impact statement-contents. 51.71 Section 51.71 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR...

78 FR 45983 - Acceptability of Corrective Action Programs for Fuel Cycle Facilities

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-30

... Programs for Fuel Cycle Facilities AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG; withdrawal... withdrawing draft NUREG-2154, ``Acceptability of Corrective Action Programs for Fuel Cycle Facilities,'' based... determine whether a submittal for a Corrective Action Program (CAP), voluntarily submitted by fuel cycle...

78 FR 55765 - Compensatory and Alternative Regulatory Measures for Nuclear Power Plant Fire Protection (CARMEN...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-11

... Nuclear Power Plant Fire Protection (CARMEN-FIRE) AGENCY: Nuclear Regulatory Commission. ACTION: Draft..., ``Compensatory and Alternative Regulatory Measures for Nuclear Power Plant Fire Protection (CARMEN-FIRE).'' In... integral part of NRC-approved fire protection programs. However, compensatory measures are not expected to...

78 FR 45573 - Compensatory and Alternative Regulatory Measures for Nuclear Power Plant Fire Protection (CARMEN...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-29

... Nuclear Power Plant Fire Protection (CARMEN-FIRE) AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Nuclear Power Plant Fire Protection (CARMEN-FIRE), Draft Report for Comment.'' DATES: Comments on this... CONTACT: Felix Gonzalez, Fire Research Branch, Division of Risk Analysis, Office of Nuclear Regulatory...

76 FR 189 - Final Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-03

.../reading-rm/doc-collections/ . In addition, regulatory guides are available for inspection at the NRC's... NUCLEAR REGULATORY COMMISSION [NRC-2010-0265] Final Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide 3...

75 FR 6065 - Dominion Energy Kewaunee, Inc.; Kewaunee Power Station; Notice of Availability of the Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-05

... Kewaunee County, Wisconsin, on the west-central shore of Lake Michigan. Possible alternatives to the proposed action (license renewal) include no action and reasonable alternative energy sources. The draft... NUCLEAR REGULATORY COMMISSION [Docket No. 50-305; NRC-2010-0041] Dominion Energy Kewaunee, Inc...

76 FR 1149 - Eagle Crest Energy Company; Notice of Availability of the Draft Environmental Impact Statement...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-07

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13123-002--California] Eagle Crest Energy Company; Notice of Availability of the Draft Environmental Impact Statement for the Eagle Mountain Pumped Storage Hydroelectric Project and Notice of Public Meetings December 23, 2010. In...

78 FR 33447 - Draft Applications for Sealed Source and Device Evaluation and Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-04

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0104] Draft Applications for Sealed Source and Device... for sealed source and device evaluation and registration. The NRC is requesting public comment on... for Sealed Source and Device Evaluation and Registration.'' The document has been updated from the...

77 FR 39695 - Idaho Power Company; Notice of Availability of Draft Environmental Assessment

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project Nos. 1975-102 and 2061-086] Idaho Power Company; Notice of Availability of Draft Environmental Assessment In accordance with the... Falls, and Elmore Counties, Idaho. Both projects occupy lands managed by the Bureau of Land Management...

Sequencing and De novo Draft Assemblies of the Fathead Minnow (Pimphales promelas)Reference Genome

EPA Science Inventory

This study was undertaken to develop genome-scale resources for the fathead minnow (Pimphales promelas) an important model organism widely used in both aquatic ecotoxicology research and in regulatory toxicity testing. We report on the first sequencing and two draft assemblies fo...

78 FR 35630 - Martin Dam Hydroelectric Project; Notice of Availability of the Draft Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-13

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 349-173] Martin Dam Hydroelectric Project; Notice of Availability of the Draft Environmental Impact Statement for the Martin Dam... the Martin Dam Hydroelectric Project (FERC No. 349), located on the Tallapoosa River in Tallapoosa...

76 FR 20657 - Wells Hydroelectric Project; Notice of Availability of the Draft Environmental Impact Statement...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2149-152] Wells Hydroelectric Project; Notice of Availability of the Draft Environmental Impact Statement for the Wells... of Energy Projects has reviewed the application for license for the Wells Hydroelectric Project (FERC...

76 FR 58543 - Draft Policy Statement on Volume Reduction and Low-Level Radioactive Waste Management

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-21

...-Level Radioactive Waste Management AGENCY: Nuclear Regulatory Commission. ACTION: Reopening of comment... for public comment a draft Policy Statement on Volume Reduction and Low-Level Radioactive Waste Management that updates the 1981 Policy Statement on Low-Level Waste Volume Reduction. The revised Policy...

10 CFR 51.73 - Request for comments on draft environmental impact statement.

Code of Federal Regulations, 2012 CFR

2012-01-01

... environmental impact statement distributed in accordance with § 51.74, and each news release provided pursuant... 10 Energy 2 2012-01-01 2012-01-01 false Request for comments on draft environmental impact statement. 51.73 Section 51.73 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION...

10 CFR 51.73 - Request for comments on draft environmental impact statement.

Code of Federal Regulations, 2011 CFR

2011-01-01

... environmental impact statement distributed in accordance with § 51.74, and each news release provided pursuant... 10 Energy 2 2011-01-01 2011-01-01 false Request for comments on draft environmental impact statement. 51.73 Section 51.73 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION...

10 CFR 51.73 - Request for comments on draft environmental impact statement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... environmental impact statement distributed in accordance with § 51.74, and each news release provided pursuant... 10 Energy 2 2010-01-01 2010-01-01 false Request for comments on draft environmental impact statement. 51.73 Section 51.73 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION...

10 CFR 51.73 - Request for comments on draft environmental impact statement.

Code of Federal Regulations, 2014 CFR

2014-01-01

... environmental impact statement distributed in accordance with § 51.74, and each news release provided pursuant... 10 Energy 2 2014-01-01 2014-01-01 false Request for comments on draft environmental impact statement. 51.73 Section 51.73 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION...

10 CFR 51.73 - Request for comments on draft environmental impact statement.

Code of Federal Regulations, 2013 CFR

2013-01-01

... environmental impact statement distributed in accordance with § 51.74, and each news release provided pursuant... 10 Energy 2 2013-01-01 2013-01-01 false Request for comments on draft environmental impact statement. 51.73 Section 51.73 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION...

78 FR 40199 - Draft Spent Fuel Storage and Transportation Interim Staff Guidance

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0140] Draft Spent Fuel Storage and Transportation Interim... Spent Fuel Storage and Transportation Interim Staff Guidance No. 24 (SFST-ISG-24), Revision 0, ``The Use of a Demonstration Program as Confirmation of Integrity for Continued Storage of High Burnup Fuel...

78 FR 11903 - Acceptability of Corrective Action Programs for Fuel Cycle Facilities

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-20

... Cycle Facilities AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG; request for public comment... ``Acceptability of Corrective Action Programs for Fuel Cycle Facilities.'' The draft NUREG provides guidance to... a fuel cycle facility is acceptable. DATES: Comments may be submitted by April 22, 2013. Comments...

75 FR 16106 - Draft Toxicological Review of Dichloromethane: In Support of Summary Information on the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

... science-based human health assessments to support the Agency's regulatory activities. The IRIS database... for the external review draft human health assessment titled, ``Toxicological Review of... developing human health assessments for inclusion in the IRIS database. The purpose of the listening session...

75 FR 6377 - Onyx Specialty Papers, Inc.; Notice of Availability of Draft Environmental Assessment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-09

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2985-006] Onyx Specialty Papers, Inc.; Notice of Availability of Draft Environmental Assessment February 2, 2010. In accordance... lieu of paper. The Commission strongly encourages electronic filings. See 18 CFR 385.2001(a)(1)(iii...

The Civil Aviation Sector in Lebanon. Part 1; Institutional Reforms

NASA Technical Reports Server (NTRS)

Baaj, M. Hadi

2002-01-01

Civil aviation is one of the key contributors to a successful economic system. This has been recognized within Lebanon, which is undertaking developing a new civil aviation strategy encompassing a program of organizational reform, coordinated internationally, to meet the challenges of the new century. Such strategy is vital, as it will provide a coherent vision for the sector, compliment the extensive investments deployed by Lebanon in its aviation infrastructure, and guide future planning and investments. The proposed Civil Aviation Strategy for Lebanon has two major components: (1) institutional reform aiming at creating effective overall legal and regulatory frameworks in-line with current international best practice; and (2) implementation of liberalization measures and open skies policy. This paper aims to: (1) present Lebanon's current institutional arrangements; (2) review the institutional arrangements in key select countries (in order to define current trends in best institutional practice); (3) discuss the proposed institutional reform (which are at the basis of Lebanon's Draft Civil Aviation Reform Law) while showing that they conform with the identified best institutional trends; and (4) outline an implementation plan. The Draft Law has been approved by the Council of Ministers and now awaits Parliamentary endorsement.

Cohort Default Rate Guide.

ERIC Educational Resources Information Center

Department of Education, Washington, DC. Default Management Div.

This guide is designed to assist schools with their Federal Family Education Loan Program (FFEL) and the William D. Ford Federal Direct Loan (Direct Loan) Program cohort default rate. The guide is a reference tool in understanding cohort default rates and processes. This guide incorporates two former guides, the "Draft Cohort Default Rate…

21 CFR 26.6 - Equivalence assessment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS... draft programs for assessing the equivalence of the respective regulatory systems in terms of quality... inspection reports), joint training, and joint inspections for the purpose of assessing regulatory systems...

76 FR 67764 - Common-Cause Failure Analysis in Event and Condition Assessment: Guidance and Research, Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-02

...: Song-Hua Shen, Division of Risk Analysis, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001; telephone: (301) 251- 7571, email: Song-Hua.Shen@nrc.gov...

76 FR 14953 - Notice of Availability of Draft Environmental Impact Statement for the Proposed Honolulu Seawater...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-18

... DEPARTMENT OF DEFENSE Department of the Army, Corps of Engineers Notice of Availability of Draft Environmental Impact Statement for the Proposed Honolulu Seawater Air Conditioning Project, Honolulu, HI AGENCY... District; Regulatory Branch (CEPOH-EC-R); Building 230; Fort Shafter, HI 96858-5440. Comments may also be...

76 FR 54502 - Energy Northwest, Columbia Generating Station; Notice of Availability of Draft Supplement 47 to...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-01

..., Washington. Possible alternatives to the proposed action (license renewal) include no action and reasonable alternative energy sources. Any interested party may submit comments on the draft supplement to the GEIS for... NUCLEAR REGULATORY COMMISSION [Docket Number 50-397; NRC-2010-0029] Energy Northwest, Columbia...

75 FR 6070 - Notice of Public Meeting on the International Atomic Energy Agency Basic Safety Standards Version...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-05

... Energy Agency Basic Safety Standards Version 3.0, Draft Safety Requirements DS379 AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Public Meeting on the International Atomic Energy Agency Basic... development of U.S. Government comments on this International Atomic Energy Agency (IAEA) draft General Safety...

78 FR 36767 - Red River Hydro LLC; Notice of Availability of Draft Environmental Assessment

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-19

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13160-004] Red River Hydro... Projects has reviewed Red River Hydro LLC's application for an original license for the Overton Lock and... assessment (draft EA). The project would be located on the Red River in Rapides Parish, Louisiana, at an...

78 FR 54655 - Center for Devices and Radiological Health: Draft Standard Operating Procedure for Level 1...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... Devices and Radiological Health's (CDRH's or the Center's) draft process to clarify and more quickly inform stakeholders when CDRH has changed its expectations relating to, or otherwise has new scientific... scientific information changes CDRH's regulatory thinking, it has been challenging for the Center to...

REFINE WETLAND REGULATORY PROGRAM

EPA Science Inventory

The Tribes will work toward refining a regulatory program by taking a draft wetland conservation code with permitting incorporated to TEB for review. Progress will then proceed in developing a permit tracking system that will track both Tribal and fee land sites within reservati...

A Legislative Reform for the Food Safety System of China: A Regulatory Paradigm Shift and Collaborative Governance.

PubMed

Han, Yonghong

2015-01-01

After describing the historical development of China's food safety system from the perspectives of legislation and administration, this article discusses progress in its food law (The Draft Amendments to Food Safety Law). As a further legislative reform for China's food safety system, the Draft Amendments to the Food Safety Law contain innovative institutional designs and manifest a regulatory paradigm shift from government-centered governance to collaborative governance. However, the Draft Amendments face challenges in their implementation. This article argues that developing collaborative governance for food safety in China can be a solution to these challenges. Based on theoretical and empirical studies of collaborative governance, this article proposes that the institutional design of collaborative governance should focus on providing obligations for administrative agencies in the process of food safety rule-making and standard-setting, increasing the independence of nongovernmental organizations, and building two-way electronic platforms for public participation.

Regulatory assessment with regulatory flexibility analysis : draft regulatory evaluation - Notice of Proposed Rulemaking -- Pipeline Safety : safety standards for increasing the maximum allowable operating pressure for natural gas transmission pipelines.

DOT National Transportation Integrated Search

2008-02-01

The Pipeline and Hazardous Materials Safety Administration (PHMSA) is proposing changes to the Federal pipeline safety regulations in 49 CFR Part 192, which cover the transportation of natural gas by pipeline. Specifically, PHMSA proposes allowing na...

Regulatory assessment with regulatory flexibility analysis and paperwork reduction act analysis : draft regulatory evaluation : Notice of Proposed Rulemaking -- Pipeline Safety : Polyamide-11 (PA-11) plastic pipe design pressures

DOT National Transportation Integrated Search

2007-06-01

The Pipeline and Hazardous Materials Safety Administration (PHMSA) is proposing changes to the Federal pipeline safety regulations in 49 CFR Part 192, which cover the transportation of natural gas by pipeline. Specifically, PHMSA is proposing to chan...

A good chew or good riddance--how to move forward in the regulation of khat consumption.

PubMed

Klein, Axel; Metaal, Pien

2010-12-01

To review the status of khat, the most recent plant based psychoactive substance to reach a global market, and consider policy making processes in general and the framework of drug control in particular. Desk review of literature on khat and wider drug policy processes. The risk assessment and classification of psychoactive drugs is a contested arena where political, economic and moral agendas collide, leaving countries that have banned khat, with significant social costs. To best manage the risks arising from the increasing availability of khat it is therefore suggested to draft a regulatory framework with clear objectives and guiding principles. Given that medical risks of khat use are modest, the objective of the regulatory framework should be the protection of consumers and community. This is best achieved by establishing processes for the quality control of khat imports, and by regulating access and availability. It should therefore not be considered as a drug to be controlled but as a licit substance that needs to be regulated. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

78 FR 69139 - Physical Security-Design Certification and Operating Reactors

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-18

... scheduled to close on October 30, 2013. The Nuclear Energy Institute (NEI) submitted a letter on October 9... NUCLEAR REGULATORY COMMISSION [NRC-2013-0225] Physical Security--Design Certification and Operating Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Standard review plan--draft section...

76 FR 47612 - NextEra Energy Seabrook, LLC; Notice of Availability of Draft Supplement 46 to the Generic...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-05

... Hampshire. Possible alternatives to the proposed action (license renewal) include no action and reasonable alternative energy sources. Any interested party may submit comments on the draft supplement to the GEIS for... NUCLEAR REGULATORY COMMISSION [NRC-2010-0206; Docket No. 50-443] NextEra Energy Seabrook, LLC...

76 FR 38676 - Gulf of Mexico (GOM), Outer Continental Shelf (OCS), Central Planning Area (CPA), Oil and Gas...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-01

... September 2008. SUPPLEMENTARY INFORMATION: BOEMRE developed the Draft SEIS for CPA Lease Sale 216/222 to consider new information made available since completion of the Multisale EIS and 2009-2012 SEIS, including information concerning the Deepwater Horizon event and spill and new regulatory requirements. This Draft SEIS...

75 FR 26220 - Public Utility District No. 1 of Snohomish County, WA; Notice of Availability of Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2157-188] Public Utility District No. 1 of Snohomish County, WA; Notice of Availability of Draft Environmental Assessment May 4... Hydroelectric Project (FERC Project No. 2157-188), located on the Sultan River 20 miles east of the city of...

76 FR 60937 - Draft License Renewal Interim Staff Guidance LR-ISG-2011-02; Aging Management Program for Steam...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

...-2011-02; Aging Management Program for Steam Generators AGENCY: Nuclear Regulatory Commission. ACTION... License Renewal Interim Staff Guidance (LR-ISG), LR-ISG-2011-02, ``Aging Management Program for Steam... using Revision 3 of NEI 97-06 to manage steam generator aging. The Draft LR-ISG revises the NRC staff's...

76 FR 38212 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-29

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0275] Notice of Issuance of Regulatory Guide AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Revision 1 of Regulatory Guide (RG) 1.179, ``Standard Format [[Page 38213

77 FR 66483 - Public Comment on the Draft Federal Urban Design Element and the Draft Update to the Federal...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-05

... NCPC review required by law. The new Federal Urban Design Element provides policies that will guide the... Historic Features Element will be available online at http://www.ncpc.gov/compplan not later than November...

Architectural Drafting. Curriculum Development. Bulletin 1779.

ERIC Educational Resources Information Center

Eppler, Thomas

This teaching guide is designed to aid high school vocational education teachers in teaching a course in architectural drafting for students who plan to become architects, interior designers and decorators, architectural draftspersons, landscape engineers, building contractors, building estimators, real estate persons or appraisers, and others.…

78 FR 19541 - Proposed Revision to Design of Structures, Components, Equipment and Systems

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-01

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0041] Proposed Revision to Design of Structures, Components, Equipment and Systems AGENCY: Nuclear Regulatory Commission. ACTION: Standard review plan-draft..., ``Design of Structures, Components, Equipment, and Systems;'' and the request for comment on NUREG-0800...

75 FR 1830 - Final Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-13

... review of applications for permits and licenses. RG 5.71, ``Cyber Security Programs for Nuclear... NUCLEAR REGULATORY COMMISSION [NRC-2010-0009] Final Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide...

The 1993-94 Educational Software Preview Guide.

ERIC Educational Resources Information Center

Best, Anita, Ed.; Mathis, Judi, Ed.

This guide lists favorably reviewed, commercially available, microcomputer software for instructional use in preschool through grade 12. The guide is organized by the following curriculum areas: art; business education; computers; health; instructional tools, including authoring systems, computer assisted drafting (CAD), classroom management,…

76 FR 31382 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-31

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0287] Notice of Issuance of Regulatory Guide AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide 8.2, Revision 1, ``Administrative Practices in Radiation Surveys and Monitoring.'' FOR FURTHER INFORMATION...

Influence of upstream disturbance on the draft-tube flow of Francis turbine under part-load conditions

NASA Astrophysics Data System (ADS)

Chen, Ting; Zheng, Xianghao; Zhang, Yu-ning; Li, Shengcai

2018-02-01

Owing to the part-load operations for the enhancement of grid flexibility, the Francis turbine often suffers from severe low-frequency and large-amplitude hydraulic instability, which is mostly pertinent to the highly unsteady swirling vortex rope in the draft tube. The influence of disturbances in the upstream (e.g., large-scale vortex structures in the spiral casing) on the draft-tube vortex flow is not well understood yet. In the present paper, the influence of the upstream disturbances on the vortical flow in the draft tube is studied based on the vortex identification method and the analysis of several important parameters (e.g., the swirl number and the velocity profile). For a small guide vane opening (representing the part-load condition), the vortices triggered in the spiral casing propagate downstream and significantly affect the swirling vortex-rope precession in the draft tube, leading to the changes of the intensity and the processional frequency of the swirling vortex rope. When the guide vane opening approaches the optimum one (representing the full-load condition), the upstream disturbance becomes weaker and thus its influences on the downstream flow are very limited.

Drafting.

ERIC Educational Resources Information Center

Hughes, Larry R.

This guide to teaching drafting, one in a series of instructional materials for junior high industrial arts education, is designed to assist teachers as they plan and implement new courses of study and as they make revisions and improvements in existing courses in order to integrate classroom learning with real-life experiences. This drafting…

Energy Efficiency for Architectural Drafting Instructors.

ERIC Educational Resources Information Center

Scharmann, Larry, Ed.

Intended primarily but not solely for use at the postsecondary level, this curriculum guide contains five units on energy efficiency that were designed to be incorporated into an existing program in architectural drafting. The following topics are examined: energy conservation awareness (residential energy use and audit procedures); residential…

Radiological Defense. Planning and Operations Guide. Revised.

ERIC Educational Resources Information Center

Office of Civil Defense (DOD), Washington, DC.

This guide is a reprint of published and draft materials from the Federal Civil Defense Guide. This guide is intended to assist the student in planning, developing, implementing and operating a local, county, or state radiological defense (RADEF) system. The state and local radiological defense program objectives are to create an effective and…

77 FR 74882 - STP Nuclear Operating Company, South Texas Project; Notice of Availability of Draft Supplement 48...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-18

... NUCLEAR REGULATORY COMMISSION [Docket Nos.: 50-498 and 50-499; NRC-2010-0375] STP Nuclear Operating Company, South Texas Project; Notice of Availability of Draft Supplement 48 to the Generic Environmental Impact Statement for License Renewal of Nuclear Plants and Public Meetings for the License Renewal of South Texas Project Notice is hereby...

77 FR 23513 - Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-19

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0070] Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft...-ISG), LR-ISG-2011-04, ``Updated Aging Management Criteria for PWR Reactor Vessel Internal Components...

Evaluating existing access opportunities for disabled persons at remote shoreline recreation sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bley, M.R.; Kearns, M.T.

1995-12-31

Draft guidelines for providing outdoor recreation access opportunities for disabled persons have been recommended by the Recreation Access Advisory Committee and in the Universal Access to Outdoor Recreation: A Design Guide. The Federal Energy Regulatory Commission requires applicants for new hydropower licenses to consider access opportunities for disabled persons at existing hydropower projects. A process for evaluating existing access opportunities for disabled persons at remote shoreline recreation sites at hydropower projects is described. The process includes five steps: (1) preparing a preliminary map of existing recreation sites; (2) data collection in the field; (3) evaluating compliance of existing facilities; (4)more » feasibility of enhancing existing facilities; and (5) designing enhancements. The process will be refined when final standards and processes are approved by the appropriate agencies and organizations.« less

A GUIDE FOR USE IN DEVELOPING TRAINING PROGRAMS IN DRAFTING AND DESIGN TECHNOLOGY.

ERIC Educational Resources Information Center

Mississippi State Dept. of Education, Jackson.

INITIAL COURSE OUTLINES WERE PREPARED BY INSTRUCTORS. INDIVIDUAL COURSES WERE THEN EXPANDED AND COORDINATED WITH OTHER COURSES. THE CURRICULUM LABORATORY STAFF REORGANIZED AND EDITED THE MATERIAL. A COMMITTEE OF INDUSTRIAL REPRESENTATIVES REVIEWED AND PERSONALLY ENDORSED IT AS BEING APPROPRIATE AND ADEQUATE FOR TRAINING DRAFTING AND DESIGN…

Illinois Occupational Skill Standards: Mechanical Drafting Cluster.

ERIC Educational Resources Information Center

Illinois Occupational Skill Standards and Credentialing Council, Carbondale.

This document, which is intended as a guide for work force preparation program providers, details the Illinois occupational skill standards for programs preparing students for employment in occupations in the mechanical drafting cluster. The document begins with a brief overview of the Illinois perspective on occupational skill standards and…

Learning to Verbally & Visually Communicate the Drafting Way.

ERIC Educational Resources Information Center

California State Dept. of Education, Sacramento. Div. of Vocational Education.

This guide contains instructional techniques that were developed for teachers of industrial education students who demonstrate a need for additional instruction in verbal/visual communication. They were written by industrial education teachers with a particular emphasis on drafting. In order to help teachers to identify those students who require…

BASINS and WEPP Climate Assessment Tools (CAT): Case Study Guide to Potential Applications (External Review Draft)

EPA Science Inventory

This draft report supports application of two recently developed water modeling tools, the BASINS and WEPP climate assessment tools. The report presents a series of short case studies designed to illustrate the capabilities of these tools for conducting scenario based assessments...

Illinois Occupational Skill Standards: Architectural Drafting Cluster.

ERIC Educational Resources Information Center

Illinois Occupational Skill Standards and Credentialing Council, Carbondale.

This document, which is intended as a guide for work force preparation program providers, details the Illinois occupational skill standards for programs preparing students for employment in occupations in the architectural drafting cluster. The document begins with a brief overview of the Illinois perspective on occupational skill standards and…

Arizona watershed framework in the Verde River watershed

Treesearch

Ren Northrup

2000-01-01

The Arizona Department of Environmental Quality, Water Quality Division drafted a six-step approach to guide its staff and local participants in developing and implementing watershed management plans. From January 1999 through June 2000, the draft Arizona Statewide Watershed Framework will be tested in Arizona's Verde River watershed. This concept proofing...

75 FR 43528 - Seeking Public Comment on Draft National Health Security Strategy Biennial Implementation Plan

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Seeking Public Comment on Draft National Health Security Strategy Biennial Implementation Plan AGENCY: Department of Health and Human... Interim Implementation Guide for the National Health Security Strategy of the United States of America...

77 FR 33253 - Regulatory Guide 8.33, Quality Management Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-05

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0126] Regulatory Guide 8.33, Quality Management Program... Regulatory Commission (NRC or Commission) is withdrawing Regulatory Guide (RG) 8.33, ``Quality Management... Quality Management Program was deleted from the regulations as part of an overall revision in 2002 of the...

76 FR 2726 - Withdrawal of Regulatory Guide 1.154

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-14

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0010] Withdrawal of Regulatory Guide 1.154 AGENCY: Nuclear Regulatory Commission. ACTION: Withdrawal of Regulatory Guide 1.154, ``Format and Content of Plant-Specific Pressurized Thermal Shock Safety Analysis Reports for Pressurized Water Reactors.'' FOR FURTHER INFORMATION CONTACT: Mekonen M. Bayssie,...

76 FR 24539 - Final Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0181] Final Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide (RG) 3.67, ``Standard Format and Content for Emergency Plans for Fuel Cycle and Materials Facilities.'' FOR FURTHER INFORMATION CONTACT: Kevin M. Ramse...

Asbestos Training Curriculum Project. [Draft Copy.

ERIC Educational Resources Information Center

Sharman, Ron

This package contains two types of asbestos training materials: (1) an instructor's guide for "Asbestos in the Home: A Homeowner's Course"; and (2) "Asbestos Abatement Certification: Small-Scale Worker Student Manual," a 16-hour course, with instructor's guide. The instructor's guide for the 6-hour homeowner's course contains…

76 FR 74831 - Aging Management of Stainless Steel Structures and Components in Treated Borated Water

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-01

... exposed to treated borated water. In response to a request from the Nuclear Energy Institute (NEI), the... NUCLEAR REGULATORY COMMISSION [NRC-2011-0256] Aging Management of Stainless Steel Structures and Components in Treated Borated Water AGENCY: Nuclear Regulatory Commission. ACTION: Draft interim staff...

78 FR 68101 - Environmental Issues Associated With New Reactors and Specific Environmental Guidance for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-13

... October 15, 2013. The Nuclear Energy Institute (NEI) submitted a letter on September 17, 2013 (Agencywide... NUCLEAR REGULATORY COMMISSION [NRC-2013-0212: NRC-2013-0211] Environmental Issues Associated With... AGENCY: Nuclear Regulatory Commission. ACTION: Draft interim staff guidance; re-opening of comment period...

A Study Guide on Holography (Draft). Test Edition. AAAS Study Guides on Contemporary Problems.

ERIC Educational Resources Information Center

Jeong, Tung H.

This is one of several study guides on contemporary problems produced by the American Association for the Advancement of Science with support of the National Science Foundation. The primary purpose of this guide is to provide a student with sufficient practical and technical information to begin independently practicing holography, with occasional…

75 FR 66398 - Notice of Availability of the Draft Supplement 45 to the Generic Environmental Impact Statement...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-28

... NUCLEAR REGULATORY COMMISSION [Docket Nos. 50-272, 50-311, and 50-354; NRC-2009-0390 and NRC-2009- 0391] Notice of Availability of the Draft Supplement 45 to the Generic Environmental Impact Statement for License Renewal of Nuclear Plants, and Public Meetings for the License Renewal of Hope Creek Generating Station and Salem Nuclear Generating...

Community Solutions for Stormwater Management: A Guide for Voluntary Long-Term Planning

EPA Pesticide Factsheets

This draft guide describes how to develop a comprehensive long-term community stormwater plan that integrates stormwater management with communities’ broader plans for economic development, infrastructure investment and environmental compliance.

Graphic Communications. Curriculum Guide.

ERIC Educational Resources Information Center

North Dakota State Board for Vocational Education, Bismarck.

This guide provides the basic foundation to develop a one-semester course based on the cluster concept, graphic communications. One of a set of six guides for an industrial arts curriculum at the junior high school level, it suggests exploratory experiences designed to (1) develop an awareness and understanding of the drafting and graphic arts…

Drafting and Design Technology Curriculum Guide.

ERIC Educational Resources Information Center

Idaho State Dept. of Education, Boise. Div. of Vocational Education.

This document provides lists of tasks, performance objectives, and enabling objectives for 1,800 hours of postsecondary instruction or 900 hours of secondary instruction in the drafting and design technology program. Following a list of tasks and an explanation of the program, the bulk of the document consists of 25 modules, each of which is a…

Military Curricula for Vocational & Technical Education. Drafting I, 6-3.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This outline of instruction, instructor guide, and student job sheets for a secondary-postsecondary-level course in Drafting I are one of a number of military-developed curriculum packages selected for adaptation to vocational instruction and curriculum development in a civilian setting. Purpose stated for the sixty-three-hour course is to teach…

Licensing Process | NREL

Science.gov Websites

Agreement After the company and NREL agree on license financial terms, NREL will draft a license agreement Group Licensing Guide and Sample License. 4. Negotiate License Language After a draft agreement has been created, NREL can tailor many of the license provisions to ensure an agreement that works for all parties

ICLUS Tools and Datasets (Version 1.2) and User's Manual ...

EPA Pesticide Factsheets

This draft Geographic Information System (GIS) tool can be used to generate scenarios of housing-density changes and calculate impervious surface cover for the conterminous United States. A draft User’s Guide accompanies the tool. This product distributes the population projections and creates land use data described in the 2009 EPA report

77 FR 36573 - DRAFT General Management Plan and Draft Environmental Impact Statement, Fort Matanzas National...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-19

... Statement (EIS) for the General Management Plan (GMP) for Fort Matanzas National Monument (Monument... EIS/GMP describes the NPS preferred alternative--Alternative B--to guide the management of the... prescriptions to ensure protection, access and enjoyment of the Monument's resources. An up-to-date GMP is...

76 FR 71044 - International Conference on Harmonisation; E2B(R3) Electronic Transmission of Individual Case...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0720...; Draft Guidance on Implementation; Data Elements and Message Specification; Appendix on Backwards and...): Implementation Guide--Data Elements and Message Specification'' (the draft E2B(R3) implementation guidance) and...

Evolution of modern approaches to express uncertainty in measurement

NASA Astrophysics Data System (ADS)

Kacker, Raghu; Sommer, Klaus-Dieter; Kessel, Rüdiger

2007-12-01

An object of this paper is to discuss the logical development of the concept of uncertainty in measurement and the methods for its quantification from the classical error analysis to the modern approaches based on the Guide to the Expression of Uncertainty in Measurement (GUM). We review authoritative literature on error analysis and then discuss its limitations which motivated the experts from the International Committee for Weights and Measures (CIPM), the International Bureau of Weights and Measures (BIPM) and various national metrology institutes to develop specific recommendations which form the basis of the GUM. We discuss the new concepts introduced by the GUM and their merits and limitations. The limitations of the GUM led the BIPM Joint Committee on Guides in Metrology to develop an alternative approach—the draft Supplement 1 to the GUM (draft GUM-S1). We discuss the draft GUM-S1 and its merits and limitations. We hope this discussion will lead to a more effective use of the GUM and the draft GUM-S1 and stimulate investigations leading to further improvements in the methods to quantify uncertainty in measurement.

Draft user's guide for UDOT mechanistic-empirical pavement design.

DOT National Transportation Integrated Search

2009-10-01

Validation of the new AASHTO Mechanistic-Empirical Pavement Design Guides (MEPDG) nationally calibrated pavement distress and smoothness prediction models when applied under Utah conditions, and local calibration of the new hot-mix asphalt (HMA) p...

Two low coverage bird genomes and a comparison of reference-guided versus de novo genome assemblies.

PubMed

Card, Daren C; Schield, Drew R; Reyes-Velasco, Jacobo; Fujita, Matthew K; Andrew, Audra L; Oyler-McCance, Sara J; Fike, Jennifer A; Tomback, Diana F; Ruggiero, Robert P; Castoe, Todd A

2014-01-01

As a greater number and diversity of high-quality vertebrate reference genomes become available, it is increasingly feasible to use these references to guide new draft assemblies for related species. Reference-guided assembly approaches may substantially increase the contiguity and completeness of a new genome using only low levels of genome coverage that might otherwise be insufficient for de novo genome assembly. We used low-coverage (∼3.5-5.5x) Illumina paired-end sequencing to assemble draft genomes of two bird species (the Gunnison Sage-Grouse, Centrocercus minimus, and the Clark's Nutcracker, Nucifraga columbiana). We used these data to estimate de novo genome assemblies and reference-guided assemblies, and compared the information content and completeness of these assemblies by comparing CEGMA gene set representation, repeat element content, simple sequence repeat content, and GC isochore structure among assemblies. Our results demonstrate that even lower-coverage genome sequencing projects are capable of producing informative and useful genomic resources, particularly through the use of reference-guided assemblies.

Two low coverage bird genomes and a comparison of reference-guided versus de novo genome assemblies

USGS Publications Warehouse

Card, Daren C.; Schield, Drew R.; Reyes-Velasco, Jacobo; Fujita, Matthre K.; Andrew, Audra L.; Oyler-McCance, Sara J.; Fike, Jennifer A.; Tomback, Diana F.; Ruggiero, Robert P.; Castoe, Todd A.

2014-01-01

As a greater number and diversity of high-quality vertebrate reference genomes become available, it is increasingly feasible to use these references to guide new draft assemblies for related species. Reference-guided assembly approaches may substantially increase the contiguity and completeness of a new genome using only low levels of genome coverage that might otherwise be insufficient for de novo genome assembly. We used low-coverage (~3.5–5.5x) Illumina paired-end sequencing to assemble draft genomes of two bird species (the Gunnison Sage-Grouse, Centrocercus minimus, and the Clark's Nutcracker, Nucifraga columbiana). We used these data to estimate de novo genome assemblies and reference-guided assemblies, and compared the information content and completeness of these assemblies by comparing CEGMA gene set representation, repeat element content, simple sequence repeat content, and GC isochore structure among assemblies. Our results demonstrate that even lower-coverage genome sequencing projects are capable of producing informative and useful genomic resources, particularly through the use of reference-guided assemblies.

76 FR 28102 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-13

... Analysis, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555... agency's ``Regulatory Guide'' series. This series was developed to describe and make available to the... guide. Licensees should identify how chosen approaches and methods (whether they are quantitative or...

75 FR 20868 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-21

...: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide 1.68.2... Water-Cooled Nuclear Power Plants.'' FOR FURTHER INFORMATION CONTACT: Mark P. Orr, Regulatory Guide... Shutdown Capability for Water-Cooled Nuclear Power Plants,'' was issued with a temporary identification as...

75 FR 37842 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-30

... INFORMATION CONTACT: R. A. Jervey, Regulatory Guide Development Branch, Division of Engineering, Office of...) 251-7404 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The U.S. Nuclear..., Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc...

76 FR 35137 - Vulnerability and Threat Information for Facilities Storing Spent Nuclear Fuel and High-Level...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-16

... High-Level Radioactive Waste AGENCY: U.S. Nuclear Regulatory Commission. ACTION: Public meeting... Nuclear Fuel, High-Level Radioactive Waste, and Reactor-Related Greater Than Class C Waste,'' and 73... Spent Nuclear Fuel (SNF) and High-Level Radioactive Waste (HLW) storage facilities. The draft regulatory...

78 FR 29392 - Embedded Digital Devices in Safety-Related Systems, Systems Important to Safety, and Items Relied...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-20

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0098] Embedded Digital Devices in Safety-Related Systems... (NRC) is issuing for public comment Draft Regulatory Issue Summary (RIS) 2013-XX, ``Embedded Digital... requirements for the quality and reliability of basic components with embedded digital devices. DATES: Submit...

77 FR 18176 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-27

... environmental assessment (EA) was prepared for Framework 47 that describes the proposed action and other.... Copies of Framework 47, the draft EA, its Regulatory Impact Review (RIR), and the Initial Regulatory.... The Framework 47 EA/ RIR/IRFA are also accessible via the Internet at http://www.nefmc.org/nemulti...

Pulpwood Harvesting: A Curriculum Guide. Preliminary Draft 1973.

ERIC Educational Resources Information Center

Mercer, R. J., Ed.

A brief introductory section contains the rationale for the course, the curriculum framework, a curriculum paradigm which indicates the approximate time ranges for each section, and notes on use of the guide. The guide itself is divided into units and subunits covering the following areas: Orientation to Pulpwood Harvesting; Tree Identification;…

Weight of evidence approaches for the identification of endocrine disrupting properties of chemicals: Review and recommendations for EU regulatory application.

PubMed

Gross, Melanie; Green, Richard M; Weltje, Lennart; Wheeler, James R

2017-12-01

A Weight-of-evidence (WoE) evaluation should be applied in assessing all the available data for the identification of endocrine disrupting (ED) properties of chemicals. The European Commission draft acts specifying criteria under the biocidal products and plant protection products regulations require that WoE is implemented for the assessment of such products. However, only some general considerations and principles of how a WoE should be conducted are provided. This paper reviews WoE approaches to distil key recommendations specifically for the evaluation of potential ED properties of chemicals. In a manner, which is consistent with existing, published WoE frameworks, the WoE evaluation of ED properties can be divided into four phases: 1) Definition of causal questions and data gathering and selection, 2) Review of individual studies, 3) Data integration and evaluation, and 4) Drawing conclusions based on inferences. Recommendations are made on how to conduct each phase robustly and transparently to help guide the WoE evaluation of potential endocrine disrupting properties of chemicals within a European regulatory context. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Farewell TID-14844; hello SECY-92-127

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lahti, G.P.; Johnson, W.J.

This year, 1992, marks the 50th anniversary of the first sustained nuclear reaction in the pile at the University of Chicago's Stagg Field. But it also marks the 30th anniversary of the publication of TID-14844, which has served as the design-basis source term for radiological assessments supporting the licensing of nuclear power plants in the United States since its inception. The conservative TID-14844 model assumes that 100% of the noble gases and 50% of the iodines are instantaneously released to the containment and are available for leakage to the environment. TID-14844 is formally embodied in the US Nuclear Regulatory Commission'smore » (NRC's) regulations in parts 10CFR100 (siting) and 10CFR50 (review of control room habitability, postaccident shielding and sampling systems). It is also embodied in a host of NRC Regulatory Guides and NUREG reports that address off-site consequences of releases of radioactivity, equipment qualification, and other postaccident radiological concerns. On April 20, 1992, the NRC staff presented to the NRC commissioners the draft Revised Accident Source Terms for Light-Water Nuclear Power Plants.' This effort is documented in SECY-92-127 and provides the first official position of the NRC in this matter.« less

75 FR 33361 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-11

... staff needs in its review of applications for permits and licenses. Revision 4 of Regulatory Guide 1.28... (Design and Construction).'' Proposed RG 1.28, Revision 4, extends the scope of the NRC's endorsement to...: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide 1.28...

Mechanical Design Technology--Modified. (Computer Assisted Drafting, Computer Aided Design). Curriculum Grant 84/85.

ERIC Educational Resources Information Center

Schoolcraft Coll., Livonia, MI.

This document is a curriculum guide for a program in mechanical design technology (computer-assisted drafting and design developed at Schoolcraft College, Livonia, Michigan). The program helps students to acquire the skills of drafters and to interact with electronic equipment, with the option of becoming efficient in the computer-aided…

75 FR 36715 - Final Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-28

... INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC or Commission) is issuing a revision..., Chief, Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear Regulatory...

75 FR 43208 - Withdrawal of Regulatory Guide 5.17

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-23

... Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555.... Introduction The U.S. Nuclear Regulatory Commission (NRC) is withdrawing Regulatory Guide 5.17, ``Truck... Development Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc. 2010-18077 Filed...

ITS enhanced bus rapid transit. Research and deployment program. [Draft for comment

DOT National Transportation Integrated Search

2000-02-01

The purpose of this guide is to provide a resource on worldwide transportation libraries and information centers for domestic and international professionals in the highway transportation field. This guide, Volume 1, is part of a multi-volume set of ...

Guide for curing of Portland cement concrete pavements : volume II.

DOT National Transportation Integrated Search

2006-08-01

Information on the current state of knowledge of curing hydraulic-cement concrete and on current curing practice : was gathered by means of a literature review and a review of current standard guidance. From this information, a : draft guide for curi...

77 FR 55480 - Draft Compliance Policy Guide Sec. 690.150 on Labeling and Marketing of Nutritional Products...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-10

... for Use To Diagnose, Cure, Mitigate, Treat, or Prevent Disease in Dogs and Cats; Availability AGENCY..., Treat, or Prevent Disease in Dogs and Cats.'' This draft CPG is intended to provide guidance to FDA... marketing of dog and cat food products that are labeled and/or marketed as intending to diagnose, cure...

75 FR 70044 - Withdrawal of Regulatory Guide 1.39

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-16

...: Hector L. Rodriguez-Luccioni, Regulatory Guide Development Branch, Division of Engineering, Office of...-251-7685 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The... N. Ridgely, Acting Chief, Regulatory Guide Development Branch, Division of Engineering, Office of...

75 FR 12804 - Withdrawal of Regulatory Guide 8.6

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0103] Withdrawal of Regulatory Guide 8.6 AGENCY: Nuclear...[uuml]ller Counters.'' FOR FURTHER INFORMATION CONTACT: Harriet Karagiannis, U.S. Nuclear Regulatory... . SUPPLEMENTARY INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC) is withdrawing...

[Draft of Guidelines for Human Body Dissection for Clinical Anatomy Education and Research and commentary].

PubMed

Shichinohe, Toshiaki; Kondo, Satoshi; Ide, Chizuka; Higuchi, Norio; Aiso, Sadakazu; Sakai, Tatsuo; Matsumura, George; Yoshida, Kazunari; Kobayashi, Eiji; Tatsumi, Haruyuki; Yaginuma, Hiroyuki; Hishikawa, Shuji; Sugimoto, Maki; Izawa, Yoshimitsu; Imanishi, Nobuaki

2011-07-01

This article analyses the Draft of Guidelines for Human Body Dissection for Clinical Anatomy Education and Research drawn by the Study Group for Future Training Systems of Surgical Skills and Procedures established by the Fiscal Year 2010 research program of the Ministry of Health, Labor and Welfare. The purpose of the Draft of Guidelines is: First, to lay out the required basic guidelines for human cadaver usage to allow medical and dental faculty to conduct clinical education and research in accordance with existing regulations. Second, the guidelines are expected to give physicians a regulatory framework to carry out cadaver training in accordance with the current legal framework. This article explains the Draft of Guidelines in detail, outlines the future of cadaver training, and describes issues which must still be solved.

[Draft of guidelines for human body dissection for clinical anatomy education and research and commentary].

PubMed

Shichinohe, Toshiaki; Kondo, Satoshi; Ide, Chizuka; Higuchi, Norio; Aiso, Sadakazu; Sakai, Tatsuo; Matsumura, George; Yoshida, Kazunari; Kobayashi, Eiji; Tatsumi, Haruyuki; Yaginuma, Hiroyuki; Hishikawa, Shuji; Sugimoto, Maki; Izawa, Yoshimitsu; Imanishi, Nobuaki

2011-06-01

This article analyses the Draft of Guidelines for Human Body Dissection for Clinical Anatomy Education and Research drawn by the Study Group for Future Training Systems of Surgical Skills and Procedures established by the Fiscal Year 2010 research program of the Ministry of Health, Labor and Welfare. The purpose of the Draft of Guidelines is: First, to lay out the required basic guidelines for human cadaver usage to allow medical and dental faculty to conduct clinical education and research in accordance with existing regulations. Second, the guidelines are expected to give physicians a regulatory framework to carry out cadaver training in accordance with the current legal framework. This article explains the Draft of Guidelines in detail, outlines the future of cadaver training, and describes issues which must still be solved.

Two Low Coverage Bird Genomes and a Comparison of Reference-Guided versus De Novo Genome Assemblies

PubMed Central

Card, Daren C.; Schield, Drew R.; Reyes-Velasco, Jacobo; Fujita, Matthew K.; Andrew, Audra L.; Oyler-McCance, Sara J.; Fike, Jennifer A.; Tomback, Diana F.; Ruggiero, Robert P.; Castoe, Todd A.

2014-01-01

As a greater number and diversity of high-quality vertebrate reference genomes become available, it is increasingly feasible to use these references to guide new draft assemblies for related species. Reference-guided assembly approaches may substantially increase the contiguity and completeness of a new genome using only low levels of genome coverage that might otherwise be insufficient for de novo genome assembly. We used low-coverage (∼3.5–5.5x) Illumina paired-end sequencing to assemble draft genomes of two bird species (the Gunnison Sage-Grouse, Centrocercus minimus, and the Clark's Nutcracker, Nucifraga columbiana). We used these data to estimate de novo genome assemblies and reference-guided assemblies, and compared the information content and completeness of these assemblies by comparing CEGMA gene set representation, repeat element content, simple sequence repeat content, and GC isochore structure among assemblies. Our results demonstrate that even lower-coverage genome sequencing projects are capable of producing informative and useful genomic resources, particularly through the use of reference-guided assemblies. PMID:25192061

Social Marketing. A Guide. First Draft.

ERIC Educational Resources Information Center

Rosenau, Fred S.

This introductory guide to nonprofit social marketing provides marketing techniques and guidelines in seven chapters. Topics covered include a general discussion of social marketing, with several definitions; market research, including factors to be considered in planning a marketing strategy, forces for and against educational changes, cluster…

Developing and Pretesting a Text Messaging Program for Health Behavior Change: Recommended Steps.

PubMed

Abroms, Lorien C; Whittaker, Robyn; Free, Caroline; Mendel Van Alstyne, Judith; Schindler-Ruwisch, Jennifer M

2015-12-21

A growing body of evidence demonstrates that text messaging-based programs (short message service [SMS]) on mobile phones can help people modify health behaviors. Most of these programs have consisted of automated and sometimes interactive text messages that guide a person through the process of behavior change. This paper provides guidance on how to develop text messaging programs aimed at changing health behaviors. Based on their collective experience in designing, developing, and evaluating text messaging programs and a review of the literature, the authors drafted the guide. One author initially drafted the guide and the others provided input and review. Steps for developing a text messaging program include conducting formative research for insights into the target audience and health behavior, designing the text messaging program, pretesting the text messaging program concept and messages, and revising the text messaging program. The steps outlined in this guide may help in the development of SMS-based behavior change programs.

Planning, Management and Evaluation: Realizing PIC Potential. Private Industry Council Guide. Working Draft.

ERIC Educational Resources Information Center

National Alliance of Business, Inc., Washington, DC.

This Planning, Management, and Evaluation (PME) guide was developed by the National Alliance of Business as part of its program of management assistance for Private Industry Councils (PICs). The guide is a tool which PICs can use to improve their capability to plan, manage, and evaluate the programs which they administer, and to establish locally…

KWOC (Key-Word-Out-of-Context) Index of US Nuclear Regulatory Commission Regulatory Guide Series

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jennings, S.D.

1990-04-01

To meet the objectives of the program funded by the Department of Energy (DOE)-Nuclear Energy (NE) Technology Support Programs, the Performance Assurance Project Office (PAPO) administers a Performance Assurance Information Program that collects, compiles, and distributes program-related information, reports, and publications for the benefit of the DOE-NE program participants. THE KWOC Index of US Nuclear Regulatory Commission Regulatory Guide Series'' is prepared as an aid in searching for specific topics in the US Nuclear Regulatory Commission, Regulatory Guide Series.

Numerical Investigation of the Flow Structure in a Kaplan Draft Tube at Part Load

NASA Astrophysics Data System (ADS)

Maddahian, R.; Cervantes, M. J.; Sotoudeh, N.

2016-11-01

This research presents numerical simulation of the unsteady flow field inside the draft tube of a Kaplan turbine at part load condition. Due to curvature of streamlines, the ordinary two-equations turbulence models fail to predict the flow features. Therefore, a modification of the Shear Stress Transport (SST-SAS) model is utilized to approximate the turbulent stresses. A guide vane, complete runner and draft tube are considered to insure the real boundary conditions at the draft tube inlet. The outlet boundary is assumed to discharge into the atmosphere. The obtained pressure fluctuations inside the draft tube are in good agreement with available experimental data. In order to further investigate the RVR formation and its movement, the λ2 criterion, relating the position of the vortex core and strength to the second largest Eigen value of the velocity gradient tensor, is employed. The method used for vortex identification shows the flow structure and vortex motion inside the draft tube accurately.

Proposed Activities to Address Regulatory Gaps and Challenges for Licensing Advanced Reactors Using Seismic Isolation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coleman, Justin Leigh; Kammerer, Annie M.; Whittaker, Andrew S.

Over the last decade, particularly since implementation of the certified design regulatory approaches outlined in 10 CFR 52, “Licenses, Certifications, and Approvals for Nuclear Power Plants,” interest has been increasing in the use of seismic isolation (SI) technology to support seismic safety in nuclear facilities. In 2009, the United States (U.S.) Nuclear Regulatory Commission (NRC) initiated research activities to develop new guidance targeted at isolated facilities because SI is being considered for nuclear power plants in the U.S. One product of that research, which was developed around a risk-informed regulatory approach, is a draft NRC NUREG series (NUREG/CR) report thatmore » investigates and discusses considerations for use of SI in otherwise traditionally founded large light water reactors (LWRs). A coordinated effort led to new provisions for SI of LWRs in the American Society of Civil Engineers standard ASCE/SEI 4-16, “Seismic Analysis of Safety Related Nuclear Structures.” The risk-informed design philosophy that underpinned development of the technical basis for these documents led to a set of proposed performance objectives and acceptance criteria intended to serve as the foundation for future NRC guidance on the use of SI and related technology. Although the guidance provided in the draft SI NUREG/CR report and ASCE/SEI 4 16 provides a sound basis for further development of nuclear power plant designs incorporating SI, these initial documents were focused on surface-founded or near-surface-founded LWRs and were, necessarily, limited in scope. For example, there is limited information in both the draft NUREG/CR report and ASCE/SEI 4-16 related to nonlinear analysis of soil-structure systems for deeply-embedded reactors, the isolation of components, and the use of vertical isolation systems. Also not included in the draft SI NUREG/CR report are special considerations for licensing of isolated facilities using the certified design approach in 10 CFR 52 and a detailed discussion of seismic probabilistic risk assessments for isolated facilities.« less

Career Education Resource Guide for Biology. Working Draft.

ERIC Educational Resources Information Center

Louisiana State Dept. of Education, Baton Rouge.

The resource guide integrates learning activities in biological science with an exploration of careers in biology or related fields. The materials are divided into seven units: tools of the scientist, basis for life, diversity (protists, plants, animals), structure and function, continuity (reproduction, development, and genetics), evolution, and…

VoCATS User Guide. [Draft.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh. Div. of Vocational Education Services.

This guide focuses on use of the North Carolina Vocational Competency Achievement Tracking System (VoCATS)-designated software in the instructional management process. (VoCATS is a competency-based, computer-based instructional management system that allows the collection of data on student performance achievement prior to, during, and following…

A Guide for Equipping Industrial Arts Facilities.

ERIC Educational Resources Information Center

American Industrial Arts Association, Washington, DC. Equipment Guide Committee.

A guide for planning new and revising existing industrial arts facilities which gives a listing of tools and equipment recommended for each of the major areas of instruction (automotive and power mechanics, ceramics, drafting, electronics, elementary, general shop, graphic arts, metalworking, plastics, and woodworking). General descriptions and…

Ottawa County Writing Process Model for PPO Assessments.

ERIC Educational Resources Information Center

Ottawa County Office of Education, OH.

This guide outlines the writing procedures for English Composition Pupil Performance Objective (PPO) assessments and tests. Procedures for both students and teachers are included for the prewriting, first draft writing, and revising/rewriting sessions. A brief guide to evaluation procedures and intervention strategies is also provided. (MM)

78 FR 53791 - Draft Program-Specific Guidance About Irradiator Licenses

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-30

... CONTACT: Tomas Herrera, Office of Federal and State Materials and Environmental Management Programs; U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001; telephone: 301-415- 7138; email: Tomas.Herrera...

NRC ARDC Guidance Support Status Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holbrook, Mark R.

This report provides a summary that reflects the progress and status of proposed regulatory design criteria for advanced non-light water reactor (LWR) designs in accordance with the Level 3 milestone M3AT-17IN2001013 in work package AT-17IN200101. These criteria have been designated as advanced reactor design criteria (ARDC) and they provide guidance to future applicants for addressing the general design criteria (GDC) that are currently applied specifically to LWR designs. This report provides a summary of Phase 2 activities related to the various tasks associated with ARDC development and the subsequent development of ARDC regulatory guidance for sodium fast reactor (SFR) andmore » modular high-temperature gas-cooled reactor (HTGR) designs. Status Report Organization: Section 2 discusses the origin of the GDC and their application to LWRs. Section 3 addresses the objective of this initiative and how it benefits the advanced non-LWR reactor vendors. Section 4 discusses the scope and structure of the initiative. Section 5 provides background on the U.S. Department of Energy (DOE) ARDC team’s original development of the proposed ARDC that were submitted to the NRC for consideration. Section 6 provides a summary of recent ARDC Phase 2 activities. Appendices A through E document the DOE ARDC team’s public comments on various sections of the NRC’s draft regulatory guide DG–1330, “Guidance for Developing Principal Design Criteria for Non-Light Water Reactors.”« less

77 FR 65364 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-26

... Economic Impact, Governance and Regulatory Process goals, objectives and strategies initially drafted on... and threats on science and data and ecosystem based fishery management. No formal actions will be...

Premise to Implement a Grading System to Evaluate the Sanitary Level in Food Service Establishments in Milan, Italy

PubMed Central

Razzini, Katia

2015-01-01

The regulatory framework of the official controls on food safety, the criteria and methods from the planning of interventions in the field of official control to the management of information flows, and the standards described in the operation manual of the local competent authorities drafted by the Lombardy Region (2011) were evaluated. A questionnaire consisting of n. 10 questions with multiple answers draft in partnership with EPAM (the Association of Provincial Public Retail and catering businesses in Milan) to n. 107 Food service establishments of Milan shows that 92% of managers approve the introduction of a grading system. The regulatory framework is planned to support the implementation of risk assignment, unfortunately the attribution of risk category of retail and catering businesses is still different among regions. PMID:27800403

Guide Book for Curriculum Development and Adaptation. Draft.

ERIC Educational Resources Information Center

United Nations Educational, Scientific and Cultural Organization, Bangkok (Thailand). Principal Regional Office for Asia and the Pacific.

This guide was developed as a cooperative initiative by UNESCO member countries to provide information about the process of development and adaptation of a flexible, competency-based curriculum, especially in vocational education. The guidebook outlines an exemplar process of education organized in 11 stages of design and development based on…

A GUIDE FOR EQUIPPING INDUSTRIAL ARTS FACILITIES.

ERIC Educational Resources Information Center

American Industrial Arts Association, Washington, DC. Equipment Guide Committee.

SCHOOL ARCHITECTS, ADMINISTRATORS, PLANNERS, AND INDUSTRIAL ARTS SUPERVISORS AND TEACHERS MAY USE THIS GUIDE IN PLANNING, REVISING, AND EVALUATING FACILITIES. IN THE FIRST PART, HAND TOOLS, MACHINES, AND GENERAL EQUIPMENT ARE LISTED FOR (1) AUTO AND POWER MECHANICS, (2) CERAMICS, (3) DRAFTING, (4) ELECTRICITY-ELECTRONICS, (5) ELEMENTARY, (6)…

Ornamental Horticulture. A Curriculum Guide. Preliminary Draft.

ERIC Educational Resources Information Center

South Carolina State Dept. of Education, Columbia. Agricultural Education Section.

Developed as part of a larger project to revise the total agricultural education curriculum in South Carolina, this curriculum guide for a 2-year ornamental horticulture course contains six functional units, each with several sub-units, and six horizontal supportive units. Each unit includes behavioral objectives, learning activities, topic…

Patient Preferences in Regulatory Benefit-Risk Assessments: A US Perspective.

PubMed

Johnson, F Reed; Zhou, Mo

Demands for greater transparency in US regulatory assessments of benefits and risks, together with growing interest in engaging patients in Food and Drug Administration regulatory decision making, have resulted in several recent regulatory developments. Although Food and Drug Administration's Center for Drug Evaluation and Research (CDER) and Center for Devices and Radiological Health (CDRH) have established patient-engagement initiatives, CDRH has proposed guidelines for considering quantitative data on patients' benefit-risk perspectives, while CDER has focused on a more qualitative approach. We summarize two significant studies that were developed in collaboration and consultation with CDER and CDRH. CDER encouraged a patient advocacy group to propose draft guidance on engaging patient and caregiver stakeholders in regulatory decision making for Duchenne muscular dystrophy. CDRH sponsored a discrete-choice experiment case study to quantify obese respondents' perspectives on "meaningful benefits." CDRH and CDER issued draft guidance in May and June 2015, respectively, on including patient-preference data in regulatory submissions. Both organizations face challenges. CDER is working on integrating qualitative data into existing evidence-based review processes and is exploring options for therapeutic areas not included on a priority list. CDRH has adopted an approach that requires patient-preference data to satisfy standards of valid scientific evidence. Although that strategy could facilitate integrating patient perspectives directly with clinical data on benefits and harms, generating such data requires building capacity. Copyright © 2016 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Flow separation in a straight draft tube, particle image velocimetry

NASA Astrophysics Data System (ADS)

Duquesne, P.; Maciel, Y.; Ciocan, G. D.; Deschênes, C.

2014-03-01

As part of the BulbT project, led by the Consortium on Hydraulic Machines and the LAMH (Hydraulic Machine Laboratory of Laval University), the efficiency and power break off in a bulb turbine has been investigated. Previous investigations correlated the break off to draft tube losses. Tuft visualizations confirmed the emergence of a flow separation zone at the wall of the diffuser. Opening the guide vanes tends to extend the recirculation zone. The flow separations were investigated with two-dimensional and two-component particle image velocimetry (PIV) measurements designed based on the information collected from tuft visualizations. Investigations were done for a high opening blade angle with a N11 of 170 rpm, at best efficiency point and at two points with a higher Q11. The second operating point is inside the efficiency curve break off and the last operating point corresponds to a lower efficiency and a larger recirculation region in the draft tube. The PIV measurements were made near the wall with two cameras in order to capture two measurement planes simultaneously. The instantaneous velocity fields were acquired at eight different planes. Two planes located near the bottom wall were parallel to the generatrix of the conical part of the diffuser, while two other bottom planes diverged more from the draft tube axis than the cone generatrix. The last four planes were located on the draft tube side and diverged more from the draft tube axis than the cone generatrix. By combining the results from the various planes, the separation zone is characterized using pseudo-streamlines of the mean velocity fields, maps of the Reynolds stresses and maps of the reverse-flow parameter. The analysis provides an estimation of the separation zone size, shape and unsteady character, and their evolution with the guide vanes opening.

Probabilistic pipe fracture evaluations for leak-rate-detection applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rahman, S.; Ghadiali, N.; Paul, D.

1995-04-01

Regulatory Guide 1.45, {open_quotes}Reactor Coolant Pressure Boundary Leakage Detection Systems,{close_quotes} was published by the U.S. Nuclear Regulatory Commission (NRC) in May 1973, and provides guidance on leak detection methods and system requirements for Light Water Reactors. Additionally, leak detection limits are specified in plant Technical Specifications and are different for Boiling Water Reactors (BWRs) and Pressurized Water Reactors (PWRs). These leak detection limits are also used in leak-before-break evaluations performed in accordance with Draft Standard Review Plan, Section 3.6.3, {open_quotes}Leak Before Break Evaluation Procedures{close_quotes} where a margin of 10 on the leak detection limit is used in determining the crackmore » size considered in subsequent fracture analyses. This study was requested by the NRC to: (1) evaluate the conditional failure probability for BWR and PWR piping for pipes that were leaking at the allowable leak detection limit, and (2) evaluate the margin of 10 to determine if it was unnecessarily large. A probabilistic approach was undertaken to conduct fracture evaluations of circumferentially cracked pipes for leak-rate-detection applications. Sixteen nuclear piping systems in BWR and PWR plants were analyzed to evaluate conditional failure probability and effects of crack-morphology variability on the current margins used in leak rate detection for leak-before-break.« less

75 FR 43207 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-23

... INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC) is issuing a revision to an existing.... Jervey, Acting Chief, Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear...

75 FR 7481 - Meeting of the Secretary's Advisory Committee on Human Research Protections

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-19

... regulatory harmonization issues through the Clinical Trials Transformation Initiative and the International..., SACHRP, prior to the close of business Thursday, March 4, 2010. Information about SACHRP and the draft...

76 FR 66311 - Draft Documents To Support Submission of an Electronic Common Technical Document; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-26

.../DevelopmentApprovalProcess/FormsSubmissionRequirements/ElectronicSubmissions/ucm253101.htm , http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/default.htm , or http...

Experimental investigation of the draft tube inlet flow of a bulb turbine

NASA Astrophysics Data System (ADS)

Vuillemard, J.; Aeschlimann, V.; Fraser, R.; Lemay, S.; Deschênes, C.

2014-03-01

In the BulbT project framework, a bulb turbine model was studied with a strongly diverging draft tube. At high discharge, flow separation occurs in the draft tube correlated to significant efficiency and power drops. In this context, a focus was put on the draft tube inlet flow conditions. Actually, a precise inlet flow velocity field is required for comparison and validation purposes with CFD simulation. This paper presents different laser Doppler velocimetry (LDV) measurements at the draft tube inlet and their analysis. The LDV was setup to measure the axial and circumferential velocity on a radius under the runner and a diameter under the hub. A method was developed to perform indirect measurement of the mean radial velocity component. Five operating conditions were studied to correlate the inlet flow to the separation in the draft tube. Mean velocities, fluctuations and frequencies allowed characterizing the flow. Using this experimental database, the flow structure was characterized. Phase averaged velocities based on the runner position allowed detecting the runner blade wakes. The velocity gradients induced by the blade tip vortices were captured. The guide vane wakes was also detected at the draft tube inlet. The recirculation in the hub wake was observed.

Mathematics Curriculum Guide for Spanish-Speaking Students, Levels E, F. Field Test. Working Draft = Guia didactica de matematicas, Niveles E, F. Edicion Experimental.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The curriculum guide for mathematics instruction in the bilingual education program of the Chicago public schools is designed to assist teachers in the instruction of limited-English-speaking students in their native language. The guide outlines, for each of two levels, lessons on absolute and relative values of numbers, whole number operations,…

Agile Multi-Function Arrays

DTIC Science & Technology

2007-07-01

been put into place to guide the standards process. 6. If the balloting results in 75% approval then the draft standard is sub- mitted to the IEEE-SA...as functionality and timeliness. Such a design process presumably guided the design for the AMRFC test bed. The multifunction apertures for...Integrated Topside should be guided by the same design process. Engaging in a spiral design process will lead to the most effective selection of research

Draft versus finished sequence data for DNA and protein diagnostic signature development

PubMed Central

Gardner, Shea N.; Lam, Marisa W.; Smith, Jason R.; Torres, Clinton L.; Slezak, Tom R.

2005-01-01

Sequencing pathogen genomes is costly, demanding careful allocation of limited sequencing resources. We built a computational Sequencing Analysis Pipeline (SAP) to guide decisions regarding the amount of genomic sequencing necessary to develop high-quality diagnostic DNA and protein signatures. SAP uses simulations to estimate the number of target genomes and close phylogenetic relatives (near neighbors or NNs) to sequence. We use SAP to assess whether draft data are sufficient or finished sequencing is required using Marburg and variola virus sequences. Simulations indicate that intermediate to high-quality draft with error rates of 10−3–10−5 (∼8× coverage) of target organisms is suitable for DNA signature prediction. Low-quality draft with error rates of ∼1% (3× to 6× coverage) of target isolates is inadequate for DNA signature prediction, although low-quality draft of NNs is sufficient, as long as the target genomes are of high quality. For protein signature prediction, sequencing errors in target genomes substantially reduce the detection of amino acid sequence conservation, even if the draft is of high quality. In summary, high-quality draft of target and low-quality draft of NNs appears to be a cost-effective investment for DNA signature prediction, but may lead to underestimation of predicted protein signatures. PMID:16243783

Head losses prediction and analysis in a bulb turbine draft tube under different operating conditions using unsteady simulations

NASA Astrophysics Data System (ADS)

Wilhelm, S.; Balarac, G.; Métais, O.; Ségoufin, C.

2016-11-01

Flow prediction in a bulb turbine draft tube is conducted for two operating points using Unsteady RANS (URANS) simulations and Large Eddy Simulations (LES). The inlet boundary condition of the draft tube calculation is a rotating two dimensional velocity profile exported from a RANS guide vane- runner calculation. Numerical results are compared with experimental data in order to validate the flow field and head losses prediction. Velocity profiles prediction is improved with LES in the center of the draft tube compared to URANS results. Moreover, more complex flow structures are obtained with LES. A local analysis of the predicted flow field using the energy balance in the draft tube is then introduced in order to detect the hydrodynamic instabilities responsible for head losses in the draft tube. In particular, the production of turbulent kinetic energy next to the draft tube wall and in the central vortex structure is found to be responsible for a large part of the mean kinetic energy dissipation in the draft tube and thus for head losses. This analysis is used in order to understand the differences in head losses for different operating points. The numerical methodology could then be improved thanks to an in-depth understanding of the local flow topology.

Regulatory decision with EPA/NRC/DOE/State Session (Panel)

DOE Office of Scientific and Technical Information (OSTI.GOV)

O`Donnell, E.

1995-12-31

This panel will cover the Nuclear Regulatory Commission`s (NRC) proposed radiation limits in the Branch Technical Position on Low-Level Radioactive Waste Performance Assessment and the Environmental Protection Agency`s (EPA) draft regulation in Part 193. Representatives from NRC and EPA will discuss the inconsistencies in these two regulations. DOE and state representatives will discuss their perspective on how these regulations will affect low-level radioactive waste performance assessments.

Multi-Ethnic Guide, An Introduction. Working Draft.

ERIC Educational Resources Information Center

Kepler, Mary, Comp.

This developmental guide was written to help children and teachers gain an understanding and respect for all ethnic groups and learn to appreciate the strengths inherent in their differences as well as in their similarities. The introductory lessons deal with the total child: first helping him to gain a better insight into himself, then studying…

Energy Efficient Homes and Small Buildings. Vocational Education, Industrial Arts Curriculum Guide. Bulletin 1698.

ERIC Educational Resources Information Center

Louisiana State Dept. of Education, Baton Rouge. Div. of Vocational Education.

This curriculum guide provides high school carpentry, construction, or drafting course teachers with material related to retrofitting a building for energy conservation. Section 1 discusses how design and construction methods affect energy use. Section 2 focuses on care and maintenance of energy efficient buildings. In addition to informative…

Resources for Ensuring Quality School-to-Work Opportunities for Young Women. Draft.

ERIC Educational Resources Information Center

Wider Opportunities for Women, Inc., Washington, DC.

This annotated bibliography lists 49 resources for ensuring high quality school-to-work opportunities for young women. These resources are grouped into 10 categories: print material for middle and high school girls; videos for middle and high school girls; administrator/school guides; curriculum guides/resources for teachers; resources for…

76 FR 35431 - Draft National Pollutant Discharge Elimination System (NPDES) General Permit for Stormwater...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-17

...: Table 1--Entities Potentially Regulated by This Permit North American Examples of affected Industry... intend the preceding table to be exhaustive, but provides it as a guide for readers regarding entities.../wastetech/guide/construction/index.cfm . B. Extension of Comment Period EPA is extending the deadline for...

Work-Based Learning: A Resource Guide for Change. Test Draft.

ERIC Educational Resources Information Center

Hudson River Center for Program Development, Glenmont, NY.

This resource guide is intended to provide New York schools, business/industry, and others with resources to develop work-based learning strategies and components. Section 1 examines the scope, foundation, categories, and operation of work-based learning. Section 2 presents detailed information about the following forms of work-based learning:…

Birds: A Study Guide for the Fourth Grade. Alaska Sea Week Curriculum Series. Draft.

ERIC Educational Resources Information Center

King, James G.; King, Mary Lou

Southeast Alaska's birds and wetlands are the subject of this elementary school teacher's guide and student workbook. Included are classroom activities and field investigations which address: (1) bird identification, habitats, adaptation, and conservation; and (2) the inhabitants, ecology and value of estuaries. Workbook activities involve the…

The Estuary Guide. Level 3: High School. Draft.

ERIC Educational Resources Information Center

Alexander, Glen; And Others

Estuaries are marine systems that serve as nurseries for animals, links in the migratory pathways, and habitat for a complex community of organisms. This curriculum guide intended for use at the high school level seeks to teach what estuaries are; provide opportunities to practice decision-making that affects estuaries; and encourage students to…

Energy Gain. Teacher's Guide and Student Guide. Net Energy Unit. Draft.

ERIC Educational Resources Information Center

McLeod, Richard J.

This module focuses on gains and losses of energy as society processes resources for energy production. It particularly focuses on the end point of energy conversion and addresses decisions which society must make concerning benefits and costs of various energy production methods and generating facilities. One class period is needed to implement…

A Plan to the Future in Home Economics Education. Draft Curriculum.

ERIC Educational Resources Information Center

Ruckes, Nina Tiglio; Mongillo, Michael

This curriculum guide was prepared to help Connecticut high schools offer an opportunity to disadvantaged high school students who are interested in home economics education to earn some college credit toward a degree in dietetic technology. The curriculum guide includes an overview of the course with a course description, recommended textbooks,…

Consumer Education Curriculum Guide for Adults. Draft.

ERIC Educational Resources Information Center

Clemson Univ., SC. Vocational Education Media Center.

The consumer education for adults guide, part of a consumer and homemaking education unit, was developed in a curriculum workshop at Winthrop College in June 1972. It was written in reference to a norm grouping. The concepts presented are: family life cycle, life style, the consumer in the economy, spending plan, consumer credit, financing…

Draft of the Martin Peña Initative Plan

EPA Pesticide Factsheets

This action plan is being developed so that EPA Region 2 can implement a strategy that focuses its programs and regulatory authorities in activities that comprehensively address the environmental issues affecting the Martin Pena communities.

75 FR 76729 - Market Access Agreement

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-09

... falls below pre-established financial performance thresholds. The draft amendment (MAA Amendment) is... System banks and the Funding Corporation that establishes certain financial performance criteria. Under... Agreement). FOR FURTHER INFORMATION CONTACT: Chris Wilson, Financial Analyst, Office of Regulatory Policy...

76 FR 8314 - Implementation Guidance for Distribution of Source Material to Exempt Persons and to General...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-14

....S. Nuclear Regulatory Commission, Washington, DC 20555-0001, telephone: 301-415-0694, e-mail: Lisa... Accession Number for the draft Part 40 implementation guidance. FOR FURTHER INFORMATION CONTACT: Lisa...

78 FR 58574 - Maintenance, Testing, and Replacement of Vented Lead-Acid Storage Batteries for Nuclear Power Plants

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-24

... time that a document is referenced. Revision 3 of Regulatory Guide 1.129 is available in ADAMS under...-251-7455; email: [email protected] . Both of the Office of Nuclear Regulatory Research, U.S... NRC is issuing a revision to an existing guide in the NRC's ``Regulatory Guide'' series. This series...

78 FR 57916 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-20

... Relating to Amendments to the Discovery Guide Used in Customer Arbitration Proceedings, as Modified by... update the Discovery Guide (``Guide'') used in customer arbitration proceedings.\\1\\ According to FINRA, the Guide supplements the discovery rules contained in the FINRA Code of Arbitration Procedure for...

77 FR 36017 - Regulatory Guide 7.3, Procedures for Picking Up and Receiving Packages of Radioactive Material

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

... Receiving Packages of Radioactive Material AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Guide (RG) 7.3, ``Procedures for Picking Up and Receiving Packages of Radioactive Material.'' The guide..., ``Administrative Guide for Verifying Compliance with Packaging Requirements for Shipment and Receipt of Radioactive...

77 FR 26521 - Withdrawal of Notice of Intent To Prepare a Joint Draft Supplemental Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-04

... conditions), the regulatory constraints and mitigation requirements for unavoidable impacts to coral reefs..., habitat surveys, and wave response modeling. The public may request copies of reports. The public will be...

Transportation. Teacher's Guide and Student Guide. Net Energy Unit. Draft.

ERIC Educational Resources Information Center

Treagust, David F.

This module is intended to increase the students' comprehension of costs, in terms of money and in energy, involved in various modes of transportation. Four main inquiries are covered in the module: (1) money saved by car pooling to school; (2) reductions in fuel consumption possible without car pooling; (3) comparisons of inter-city and urban…

Agricultural Sales and Services. A Curriculum Guide. Preliminary Draft.

ERIC Educational Resources Information Center

South Carolina State Dept. of Education, Columbia. Agricultural Education Section.

This guide outlines what should be taught to provide training for high school students in agricultural sales and services, and to some degree how and with what resources. The general framework of this 1-year course outline is presented as a problemsolving approach wherein objectives spell out the expected outcomes. After an introductory section on…

A Guide for Developing a Business Plan for Charter Schools.

ERIC Educational Resources Information Center

Charter Friends National Network, St. Paul, MN.

This guide may be used by charter school operators in developing a business plan that can be used as a management tool in individual schools and in preparing applications for charters, renewals, and grants and loans. A sound business plan must reflect the school's ideas, assets, and needs clearly and succinctly. Drafting a business plan begins…

Presenter's Guide to Perspectives (Law-Related Education). Draft.

ERIC Educational Resources Information Center

Pratt, Robert B.

This document is the presenter's guide to SO 008 871. The document is the result of three and one-half years of effort to improve social studies in the secondary schools in Iowa. Perspectives, part one of the two-part series, presents information and background to aid in the reform, innovation, and evaluation of social studies programs. This…

76 FR 70169 - Draft Supplement 2 to Final Environmental Statement Related to the Operation of Watts Bar Nuclear...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-10

... this page, the public can gain entry into ADAMS, which provides text and image files of the NRC's... the Nuclear Regulatory Commission. Stephen J. Campbell, Chief, Watts Bar Special Projects Branch...

Proceedings of the Joint Logistics Commanders Joint Policy Coordinating Group on Computer Resource Management; Computer Software Management Software Workshop, 2-5 April 1979.

DTIC Science & Technology

1979-08-21

Appendix s - Outline and Draft Material for Proposed Triservice Interim Guideline on Application of Software Acceptance Criteria....... 269 Appendix 9...AND DRAFT MATERIAL FOR PROPOSED TRISERVICE INTERIM GUIDELINE ON APPLICATION OF SOFTWARE ACCEPTANCE CRITERIA I I INTRODUCTION The purpose of this guide...contract item (CPCI) (code) 5. CPCI test plan 6. CPCI test procedures 7. CPCI test report 8. Handbooks and manuals. Al though additional material does

75 FR 9626 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-03

... maintain variables and systems that can affect the fission process, the integrity of the reactor core, the... on some other defined basis. GDC 24 requires that interconnection of the protection and control..., Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc...

75 FR 45171 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-02

... Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555...-3040. This guide describes some engineering practices and methods generally considered by the NRC to be... they reflect the latest general engineering approaches that are acceptable to the NRC staff. If future...

Guida Didattica per l'Insegnamento della Matematica. Livelli G, H = Mathematics Curriculum Guide for Italian-Speaking Students, Levels G and H. Working Draft.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The curriculum guide is for levels G and H of the mathematics segment of Chicago's bilingual education program for limited-English-speaking native Italian-speaking students. It includes specific instructional objectives and worksheets for teaching the mathematical concepts of place value, whole numbers, rational numbers, measurement, geometry, and…

Sea Animals: A Study Guide for the First Grade. Alaska Sea Week Curriculum Series. Draft.

ERIC Educational Resources Information Center

Barr, Nancy

Over 40 activities dealing with marine animals comprise this guide for first-grade teachers. By combining meaningful time at the beach with appropriate classroom work, first graders should be able to learn about the habitats, lives, characteristics, and names of some common ocean invertebrates, fish, and mammals. In addition to the lesson plans…

A New Concept: Use of Negotiations in the Hazardous Waste Facility Permitting Process in New Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, G.J.; Rose, W.M.; Domenici, P.V.

This paper describes a unique negotiation process leading to authorization of the U.S. Department of Energy (DOE) to manage and dispose remote-handled (RH) transuranic (TRU) mixed wastes at the Waste Isolation Pilot Plant (WIPP). The negotiation process involved multiple entities and individuals brought together under authority of the New Mexico Environment Department (NMED) to discuss and resolve technical and facility operational issues flowing from an NMED-issued hazardous waste facility Draft Permit. The novel negotiation process resulted in numerous substantive changes to the Draft Permit, which were ultimately memorialised in a 'Draft Permit as Changed'. This paper discusses various aspects ofmore » the negotiation process, including events leading to the negotiations, regulatory basis for the negotiations, negotiation participants, and benefits of the process. (authors)« less

77 FR 55877 - Initial Test Program of Condensate and Feedwater Systems for Light-Water Reactors

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-11

...-492- 3668; email: [email protected] . NRC's Agencywide Documents Access and Management System... Systems for Light-Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide; issuance... Systems for Boiling Water Reactor Power Plants.'' This regulatory guide is being revised to: (1) Expand...

77 FR 64564 - Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-22

...-Basis Hurricane and Hurricane Missiles AGENCY: Nuclear Regulatory Commission. ACTION: Proposed interim...-ISG-024, ``Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles....221, ``Design-Basis Hurricane and Hurricane Missiles for Nuclear Power Plants.'' DATES: Submit...

78 FR 36278 - Fuel Oil Systems for Emergency Power Supplies

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-17

... this notice (if that document is available in ADAMS) is provided the first time that a document is..., Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001... issuing a revision to an existing guide in the NRC's ``Regulatory Guide'' series. This series was...

75 FR 16525 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-01

... CONTACT: Mekonen M. Bayssie, Regulatory Guide Development Branch, Division of Engineering, Office of...) 251-7489 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The U.S..., Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc. 2010-7391 Filed 3-31-10; 8:45 am...

The development of a guideline implementability tool (GUIDE-IT): a qualitative study of family physician perspectives

PubMed Central

2014-01-01

Background The potential of clinical practice guidelines has not been realized due to inconsistent adoption in clinical practice. Optimising intrinsic characteristics of guidelines (e.g., its wording and format) that are associated with uptake (as perceived by their end users) may have potential. Using findings from a realist review on guideline uptake and consultation with experts in guideline development, we designed a conceptual version of a future tool called Guideline Implementability Tool (GUIDE-IT). The tool will aim to involve family physicians in the guideline development process by providing a process to assess draft guideline recommendations. This feedback will then be given back to developers to consider when finalizing the recommendations. As guideline characteristics are best assessed by end-users, the objectives of the current study were to explore how family physicians perceive guideline implementability, and to determine what components should comprise the final GUIDE-IT prototype. Methods We conducted a qualitative study with family physicians inToronto, Ontario. Two experienced investigators conducted one-hour interviews with family physicians using a semi-structured interview guide to 1) elicit feedback on perceptions on guideline implementability; 2) to generate a discussion in response to three draft recommendations; and 3) to provide feedback on the conceptual GUIDE-IT. Sessions were audio taped and transcribed verbatim. Data collection and analysis were guided by content analyses. Results 20 family physicians participated. They perceived guideline uptake according to facilitators and barriers across 6 categories of guideline implementability (format, content, language, usability, development, and the practice environment). Participants’ feedback on 3 draft guideline recommendations were grouped according to guideline perception, cognition, and agreement. When asked to comment on GUIDE-IT, most respondents believed that the tool would be useful, but urged to involve “regular” or community family physicians in the process, and suggested that an online system would be the most efficient way to deliver it. Conclusions Our study identified facilitators and barriers of guideline implementability from the perspective of community and academic family physicians that will be used to build our GUIDE-IT prototype. Our findings build on current knowledge by showing that family physicians perceive guideline uptake mostly according to factors that are in the control of guideline developers. PMID:24476491

Model competencies in regulatory therapeutic product assessment: Health Canada's good review guiding principles as a reviewing community's code of intellectual conduct.

PubMed

Lim, Robyn R

2007-08-01

This article describes some work from the Therapeutic Products Directorate of Health Canada regarding Good Review Practices (GRP). Background information is provided on the Therapeutic Products Directorate (TPD) and its regulatory activities regarding drug and medical device assessment in both the pre- and post-market setting. The TPD Good Review Guiding Principles (GRGP) are described which include a Definition of a Good Therapeutic Product Regulatory Review, Ten Hallmarks of a Good Therapeutic Product Regulatory Review and Ten Precepts. Analysis of the guiding principles discusses possible linkages between the guiding principles and intellectual virtues. Through this analysis an hypothesis is developed that the guiding principles outline a code of intellectual conduct for Health Canada's reviewers of evidence for efficacy, safety, manufacturing quality and benefit-risk regarding therapeutic products. Opportunities to advance therapeutic product regulatory review as a scientific discipline in its own right and to acknowledge that these reviewers constitute a specific community of practice are discussed. Integration of intellectual and ethical approaches across therapeutic product review sectors is also suggested.

78 FR 37261 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-20

... Change Relating to Amendments to the Discovery Guide Used in Customer Arbitration Proceedings June 13... Discovery Guide (``Guide'') used in customer arbitration proceedings to provide general guidance on electronic discovery (``e-discovery'') issues and product cases and to clarify the existing provision...

77 FR 18872 - Availability of Electric Power Sources

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-28

... the first time that document is referenced. Revision 1 of Regulatory Guide 1.93 is available.... Introduction The NRC is issuing a revision to an existing guide in the NRC's ``Regulatory Guide'' series. This series was developed to describe and make available to the public information such as methods that are...

75 FR 16202 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

..., Revision 2, ``An Acceptable Model and Related Statistical Methods for the Analysis of Fuel Densification.... Introduction The U.S. Nuclear Regulatory Commission (NRC) is issuing a revision to an existing guide in the... nuclear power reactors. To meet these objectives, the guide describes statistical methods related to...

Regulatory Acceptance of Alternative Methods in the Development and Approval of Pharmaceuticals.

PubMed

Beken, Sonja; Kasper, Peter; van der Laan, Jan-Willem

Animal studies may be carried out to support first administration of a new medicinal product to either humans or the target animal species, or before performing clinical trials in even larger populations, or before marketing authorisation, or to control quality during production. Ethical and animal welfare considerations require that animal use is limited as much as possible. Directive 2010/63/EU on the protection of animals used for scientific purposes unambiguously fosters the application of the principle of the 3Rs when considering the choice of methods to be used.As such, today, the 3Rs are embedded in the relevant regulatory guidance both at the European (European Medicines Agency (EMA)) and (Veterinary) International Conference on Harmonization ((V)ICH) levels. With respect to non-clinical testing requirements for human medicinal products, reduction and replacement of animal testing has been achieved by the regulatory acceptance of new in vitro methods, either as pivotal, supportive or exploratory mechanistic studies. Whilst replacement of animal studies remains the ultimate goal, approaches aimed at reducing or refining animal studies have also been routinely implemented in regulatory guidelines, where applicable. The chapter provides an overview of the implementation of 3Rs in the drafting of non-clinical testing guidelines for human medicinal products at the level of the ICH. In addition, the revision of the ICH S2 guideline on genotoxicity testing and data interpretation for pharmaceuticals intended for human use is discussed as a case study.In October 2010, the EMA established a Joint ad hoc Expert Group (JEG 3Rs) with the mandate to improve and foster the application of 3Rs principles to the regulatory testing of medicinal products throughout their lifecycle. As such, a Guideline on regulatory acceptance of 3R testing approaches was drafted that defines regulatory acceptance and provides guidance on the scientific and technical criteria for regulatory acceptance of 3R testing approaches, including a process for collection of real-life data (safe harbour). Pathways for regulatory acceptance of 3R testing approaches are depicted and a new procedure for submission and evaluation of a proposal for regulatory acceptance of 3R testing approaches is described.

Six years after the NRC review of EPA's Draft IRIS Toxicological Review of Formaldehyde: Regulatory implications of new science in evaluating formaldehyde leukemogenicity.

PubMed

Mundt, Kenneth A; Gentry, P Robinan; Dell, Linda D; Rodricks, Joseph V; Boffetta, Paolo

2018-02-01

Shortly after the International Agency for Research on Cancer (IARC) determined that formaldehyde causes leukemia, the United States Environmental Protection Agency (EPA) released its Draft IRIS Toxicological Review of Formaldehyde ("Draft IRIS Assessment"), also concluding that formaldehyde causes leukemia. Peer review of the Draft IRIS Assessment by a National Academy of Science committee noted that "causal determinations are not supported by the narrative provided in the draft" (NRC 2011). They offered recommendations for improving the Draft IRIS assessment and identified several important research gaps. Over the six years since the NRC peer review, significant new science has been published. We identify and summarize key recommendations made by NRC and map them to this new science, including extended analysis of epidemiological studies, updates of earlier occupational cohort studies, toxicological experiments using a sensitive mouse strain, mechanistic studies examining the role of exogenous versus endogenous formaldehyde in bone marrow, and several critical reviews. With few exceptions, new findings are consistently negative, and integration of all available evidence challenges the earlier conclusions that formaldehyde causes leukemia. Given formaldehyde's commercial importance, environmental ubiquity and endogenous production, accurate hazard classification and risk evaluation of whether exposure to formaldehyde from occupational, residential and consumer products causes leukemia are critical. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

77 FR 67678 - Content Specifications and Shielding Evaluations for Type B Transportation Packages

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-13

...The U.S. Nuclear Regulatory Commission (NRC or the Commission) is issuing for public comment Draft Regulatory Issue Summary (RIS) 2012-XX, ``Content Specifications and Shielding Evaluations for Type B Transportation Packages.'' This RIS clarifies the NRC's use of staff guidance in NUREG-1609, ``Standard Review Plan for Transport Packages for Radioactive Material,'' for the review of content specifications and shielding evaluations included in the Certificates of Compliance (CoC) and safety analysis reports (SARs) for Type B transportation packages.

78 FR 45167 - Notification of Submission to the Secretary of Agriculture; Pesticides, Agricultural Worker...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-26

... Notification of Submission to the Secretary of Agriculture; Pesticides, Agricultural Worker Protection Standard... of Agriculture. SUMMARY: This document notifies the public as required by the Federal Insecticide... United States Department of Agriculture (USDA) a draft regulatory document concerning Pesticides...

76 FR 19095 - Pesticide Program Dialogue Committee; Notice of Public Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-06

... EPA Administrator on issues associated with pesticide regulatory development and reform initiatives... Program Dialogue Committee (PPDC) is scheduled for April 20-21, 2011. A draft agenda is under development that will include Integrated Pest Management, Pollinator Protection, Children/Worker Risk Policy...

21 CFR 10.95 - Participation in outside standard-setting activities.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., professional societies, and academic institutions. (4) An FDA employee appointed as the liaison representative... associations, professional societies, and academic institutions. (5) An FDA employee appointed as the liaison... validation of analytical methods for regulatory use, drafting uniform laws and regulations, and the...

77 FR 33253 - Regulatory Guide 8.24, Revision 2, Health Physics Surveys During Enriched Uranium-235 Processing...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-05

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0115] Regulatory Guide 8.24, Revision 2, Health Physics..., ``Health Physics Surveys During Enriched Uranium-235 Processing and Fuel Fabrication'' was issued with a... specifically with the following aspects of an acceptable occupational health physics program that are closely...

78 FR 35330 - Initial Test Programs for Water-Cooled Nuclear Power Plants

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-12

... this notice is provided the first time that a document is referenced. Revision 4 of Regulatory Guide 1... FURTHER INFORMATION CONTACT: Mark Orr, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory... Guide'' series. This series was developed to describe and make available to the public information such...

76 FR 63541 - Design-Basis Hurricane and Hurricane Missiles for Nuclear Power Plants

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-13

... Hurricane Missiles for Nuclear Power Plants AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide... regulatory guide, (RG) 1.221, ``Design-Basis Hurricane and Hurricane Missiles for Nuclear Power Plants... missiles that a nuclear power plant should be designed to withstand to prevent undue risk to the health and...

75 FR 45172 - Withdrawal of Regulatory Guides 3.44 and 3.49

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-02

... Format and Content for the Safety Analysis Report for an Independent Spent Fuel Storage Installation... on the format and content of the safety analysis report that is required as part of an application to...: Nuclear Regulatory Commission. ACTION: Withdrawal of Regulatory Guide 3.44, ``Standard Format and Content...

Thermal overload protection for electric motors on safety-related motor-operated valves: Generic Issue II. E. 6. 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rothberg, O.

1988-06-01

NRC regulatory positions, as stated in Regulatory Guide 1.106, Revision 1, have been identified by the Office for Analysis and Evaluation of Operational Data (AEOD) as potential contributors to valve motor burnout. AEOD is particularly concerned about the allowed policy of bypassing thermal overload devices during normal or accident conditions. Regulatory Guide 1.106 favors compromising the function of thermal overload devices in favor of completing the safety-related action of valves. The purpose of this study was to determine if the guidance contained in Regulatory Guide 1.106 is appropriate and, if not, to recommend the necessary changes. This report describes thermalmore » overload devices commonly used to protect safety-related valve operator motors. The regulatory guidelines stated in Regulatory Guide 1.106 along with the limitations of thermal overload protection are discussed. Supplements and alternatives to thermal overload protection are also described. Findings and conclusions of several AEOD reports are discussed. Information obtained from the standard review plan, standard technical specifications, technical specifications from representative plants, and several papers are cited.« less

Regulatory issues with multiplicity in drug approval: Principles and controversies in a changing landscape.

PubMed

Benda, Norbert; Brandt, Andreas

2018-01-01

Recently, new draft guidelines on multiplicity issues in clinical trials have been issued by European Medicine Agency (EMA) and Food and Drug Administration (FDA), respectively. Multiplicity is an issue in clinical trials, if the probability of a false-positive decision is increased by insufficiently accounting for testing multiple hypotheses. We outline the regulatory principles related to multiplicity issues in confirmatory clinical trials intended to support a marketing authorization application in the EU, describe the reasons for an increasing complexity regarding multiple hypotheses testing and discuss the specific multiplicity issues emerging within the regulatory context and being relevant for drug approval.

Career Development Exemplary Project. The First Draft of a Curriculum Guide for Grade Nine.

ERIC Educational Resources Information Center

Ailer, Audrey J.; And Others

The guide represents an effort to implement the first phase of an exploration of careers curriculum designed to provide in-depth exploration of jobs previously surveyed by students in the seventh and eighth grade career awareness phase of the program. The following three units are included for each of 11 subject areas: an awareness unit, 4 to 9…

Draft Declaration of Guiding Principles on the Use of Satellite Broadcasting for the Free Flow of Information, The Spread of Education and Greater Cultural Exchange.

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Paris (France).

Recognizing that communications satellites are capable of broadcasting programs for individual or community reception, and that the Universal Declaration of Human Rights proclaims that everyone has the right to receive and impart information through any media regardless of frontiers, the following guiding principles are proclaimed: (1) Satellite…

75 FR 22674 - U.S. Department of State Advisory Committee on Private International Law Study Group Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-29

... Intellectual Property (IP) The Department of State, Office of the Legal Adviser, Private International Law and... rights in intellectual property, as well as possible future work in UNCITRAL on an IP licensing guide.../689), as well as the draft text of the IP supplement to the Guide (A/CN.9/700 and Add. 1-7) that will...

Curriculum Guide for Italian Language Arts. Literature Levels AB = Guida alla Lettura della Lingua Italiana Letteratura Ciclo A & B. Working Draft.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

A curriculum and teaching guide for introductory literature appreciation in the Chicago public schools is an orientation for the bilingual teacher of Italian students. Concepts such as rhyme and personification are developed for the teacher. For each of the two levels included, the section begins with a list of specific performance objectives,…

Curriculum Guide for Spanish Language Arts, Level D. Working Draft = Guia para la ensenanza de las artes del lenguaje espanol, nivel D. Edicion experimental.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The curriculum guide for teachers of Spanish language arts for native Spanish-speaking primary students in the Chicago public schools' bilingual education program is introduced by a section outlining the program and defining the areas to be emphasized in the program: word attack, comprehension skills, study skills, and literature appreciation.…

Curriculum Guide for Spanish Language Arts, Level E. Working Draft = Guia para la ensenanza de las artes del lenguaje espanol, nivel E. Edicion experimental.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The curriculum guide for teachers of Spanish language arts for native Spanish-speaking primary students in the Chicago public schools' bilingual education program is introduced by a section outlining the program and defining the areas to be emphasized in the program: word attack, comprehension skills, study skills, and literature appreciation.…

[International trend of guidance for nanomaterial risk assessment].

PubMed

Hirose, Akihiko

2013-01-01

In the past few years, several kinds of opinions or recommendations on the nanomaterial safety assessment have been published from international or national bodies. Among the reports, the first practical guidance of risk assessment from the regulatory body was published from the European Food Safety Authorities in May 2011, which included the determination of exposure scenario and toxicity testing strategy. In October 2011, European Commission (EC) adopted the definition of "nanomaterial" for regulation. And more recently, Scientific Committee on Consumer Safety of EC released guidance for assessment of nanomaterials in cosmetics in June 2012. A series of activities in EU marks an important step towards realistic safety assessment of nanomaterials. On the other hand, the US FDA announced a draft guidance for industry in June 2011, and then published draft guidance documents for both "Cosmetic Products" and "Food Ingredients and Food Contact Substances" in April 2012. These draft documents do not restrictedly define the physical properties of nanomaterials, but when manufacturing changes alter the dimensions, properties, or effects of an FDA-regulated product, the products are treated as new products. Such international movements indicate that most of nanomaterials with any new properties would be assessed or regulated as new products by most of national authorities in near future, although the approaches are still case by case basis. We will introduce such current international activities and consideration points for regulatory risk assessment.

Guiding College Students to Develop Academic Self-Regulatory Skills

ERIC Educational Resources Information Center

Chen, Pin-Hwa

2011-01-01

This study aimed to explore the efficaciousness of a guiding model for Taiwanese college students employed to develop their academic self-regulatory skills. Twenty-eight undergraduates in a university in southern Taiwan were recruited as participants. The participants received training on the proposed guiding model and were asked to take their own…

77 FR 37717 - Electrical Cable Test Results and Analysis During Fire Exposure

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-22

... Fire Exposure AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG; request for comment. SUMMARY...-2128, ``Electrical Cable Test Results and Analysis during Fire Exposure (ELECTRA-FIRE), A Consolidation of the Three Major Fire-Induced Circuit and Cable Failure Experiments Performed between 2001 and 2011...

76 FR 81998 - Methodology for Low Power/Shutdown Fire PRA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-29

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0295] Methodology for Low Power/Shutdown Fire PRA AGENCY..., ``Methodology for Low Power/Shutdown Fire PRA--Draft Report for Comment.'' DATES: Submit comments by March 01... risk assessment (PRA) method for quantitatively analyzing fire risk in commercial nuclear power plants...

10 CFR 51.91 - Final environmental impact statement-contents.

Code of Federal Regulations, 2011 CFR

2011-01-01

... comment is discussed individually in the text of the statement. (3) If changes in the draft environmental... 10 Energy 2 2011-01-01 2011-01-01 false Final environmental impact statement-contents. 51.91 Section 51.91 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR...

78 FR 40474 - Environmental Impact Statements; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-05

..., Draft EIS, USA, TX, Implementation of Energy, Water, and Solid Waste Sustainability Initiatives at Fort... Land Management (BLM) has adopted the Federal Energy Regulatory Commission's FEIS 20100001, filed 01/07.... 20130197, Final EIS, USACE, FL, Everglades Agricultural Area A- 1 Shallow Flow Equalization Basin, Review...

78 FR 1574 - Regulatory Agenda

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

... Infusion Pumps. 281 Requirements for the 0910-AG59 Testing and Reporting of Tobacco Product Constituents... Use Devices: Issuance of Draft Special Controls Guidance for Infusion Pumps Legal Authority: 21 U.S.C... proposing to amend the classification of infusion pumps from class II (performance standards) to class II...

CRYPTOSPORIDIUM LOG INACTIVATION CALCULATION METHODS

EPA Science Inventory

Appendix O of the Surface Water Treatment Rule (SWTR) Guidance Manual introduces the CeffT10 (i.e., reaction zone outlet C value and T10 time) method for calculating ozone CT value and Giardia and virus log inactivation. The LT2ESWTR Pre-proposal Draft Regulatory Language for St...

76 FR 14108 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-15

..., telephone (301) 251-7569 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The U.S.... Thomas H. Boyce, Chief, Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear...

75 FR 69458 - Notice of Draft NIJ Law Enforcement Duty Holster Selection and Application Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

... and organizations, research, development and scientific communities, and all other stakeholders and... consideration are directed to the following Web site: http://www.justnet.org . DATES: Comments must be received...

75 FR 44284 - Notice of Draft NIJ Criminal Justice Restraints Selection and Application Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-28

...: Comments must be received on or before August 27, 2010. FOR FURTHER INFORMATION CONTACT: Casandra Robinson... casandra.robinson@usdoj.gov . Kristina Rose, Acting Director, National Institute of Justice. [FR Doc. 2010...

Mathematics Curriculum Guide for Spanish-Speaking Students, Levels A, B, C, D, Field Test. Working Draft = Guia didactica de Matematicas, Niveles A, B, C, D. Edicion Experimental.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The introductory level curriculum guide for bilingual education for Spanish-speaking children in the Chicago public schools is divided into four difficulty levels and is designed to facilitate acquisition of mathematical concepts by presenting them in the children's native language. At each level, the concepts covered include the meaning of…

Curriculum Guide for Spanish Language Arts, Elementary Level L. Field Test, Working Draft = Guia para la ensenanza de las artes del lenguaje espanol, nivel elemental intermedio L. Edicion experimental.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The curriculum guide for teachers of Spanish language arts for native Spanish-speaking students in the Chicago public schools' bilingual education program is introduced by a section outlining the program and defining the areas to be emphasized in the program: word attack, comprehension skills, study skills, and literature appreciation. Sections…

Curriculum Guide for Spanish Language Arts, Elementary Level N. Field Test, Working Draft = Guia para la ensenanza de las artes del lenguaje espanol, nivel elemental adelantado N. Edicion experimental.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The curriculum guide for teachers of Spanish language arts for native Spanish-speaking students in the Chicago public schools' bilingual education program is introduced by a section outlining the program and defining the areas to be emphasized in the program: word attack, comprehension skills, study skills, and literature appreciation. Sections…

Curriculum Guide for Spanish Language Arts, Elementary Level M. Field Test, Working Draft = Guia para la ensenanza de las artes del lenguaje espanol, nivel elemental adelantado M. Edicion experimental.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The curriculum guide for teachers of Spanish language arts for native Spanish-speaking students in the Chicago public schools' bilingual education program is introduced by a section outlining the program and defining the areas to be emphasized in the program: word attack, comprehension skills, study skills, and literature appreciation. Sections…

Writing from Personal Experience: How To Turn Your Life into Salable Prose.

ERIC Educational Resources Information Center

Kelton, Nancy Davidoff

Through the guide's 39 chapters, a person can learn how to write his or her life, and how to prepare, submit, and sell the story. The guide offers advice on: ideas--how to spot them, enjoy them, and jot them down; first drafts and the value in simply telling the story and revising later; establishing a writing routine and keeping it; the hows and…

78 FR 73898 - Operator Licensing Examination Standards for Power Reactors

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-09

... Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG; request for comment. SUMMARY: The U.S..., Revision 10, ``Operator Licensing Examination Standards for Power Reactors.'' DATES: Submit comments [email protected] . Both of the Office of New Reactors; or Timothy Kolb, Office of Nuclear Reactor Regulation, U...

76 FR 73720 - Knowledge and Abilities Catalog for Nuclear Power Plant Operators: Westinghouse AP1000...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0272] Knowledge and Abilities Catalog for Nuclear Power...) is issuing for public comment a draft NUREG, NUREG-2103, Revision 0, ``Knowledge and Abilities Catalog for Nuclear Power Plant Operators: Westinghouse AP1000 Pressurized-Water Reactors. DATES: Submit...

77 FR 3009 - Knowledge and Abilities Catalog for Nuclear Power Plant Operators: Advanced Boiling Water Reactors

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-20

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0010] Knowledge and Abilities Catalog for Nuclear Power... comment a draft NUREG, NUREG-2104, Revision 0, ``Knowledge and Abilities Catalog for Nuclear Power Plant... developed using this Catalog along with the Operator Licensing Examination Standards for Power Reactors...

78 FR 63219 - International Conference on Harmonisation; Draft Guidance on Elemental Impurities; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-23

... appropriate limits for impurities, and emphasizes control of supply chains and risk assessments. It is... expectations for test requirements and regulatory filings, and a global policy for limiting elemental... written comments to the Division of Dockets Management (HFA-305), Food and Drug Administration, 5630...

76 FR 39998 - Semiannual Regulatory Agenda, Spring 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-07

.... It would change the definition of high-risk animal, which will change the types of animals eligible..., subject to the availability of appropriated funds, receive payments for certified citrus nursery stock... 3271 Environmental Impact Statement. Comment Period End 03/23/04 Notice of Availability of Draft 07/17...

77 FR 77117 - Proposed Revision 0 on Access Authorization-Operational Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-31

...--Operational Program AGENCY: Nuclear Regulatory Commission. ACTION: Standard review plan-draft section revision... public comment on NUREG-0800, ``Standard Review Plan for the Review of Safety Analysis Reports for... seeks comments on the new Section 13.6.4 of the Standard Review Plan (SRP) concerning implementation of...

77 FR 64834 - Computational Fluid Dynamics Best Practice Guidelines for Dry Cask Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0250] Computational Fluid Dynamics Best Practice... public comments on draft NUREG-2152, ``Computational Fluid Dynamics Best Practice Guidelines for Dry Cask... System (ADAMS): You may access publicly-available documents online in the NRC Library at http://www.nrc...

76 FR 5582 - Whitestone Power and Communications; Notice of Intent To File License Application, Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-01

... Communications. e. Name of Project: Whitestone Poncelet RISEC Project.\\1\\ \\1\\ The project was named the... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13305-001] Whitestone Power and Communications; Notice of Intent To File License Application, Filing of Draft Application, Request...

10 CFR 7.21 - Cost of duplication of documents.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Cost of duplication of documents. 7.21 Section 7.21 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.21 Cost of duplication of documents. Copies of the records, reports, transcripts, minutes, appendices, working papers, drafts, studies, agenda, or other...

10 CFR 7.21 - Cost of duplication of documents.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Cost of duplication of documents. 7.21 Section 7.21 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.21 Cost of duplication of documents. Copies of the records, reports, transcripts, minutes, appendices, working papers, drafts, studies, agenda, or other...

10 CFR 7.21 - Cost of duplication of documents.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Cost of duplication of documents. 7.21 Section 7.21 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.21 Cost of duplication of documents. Copies of the records, reports, transcripts, minutes, appendices, working papers, drafts, studies, agenda, or other...

77 FR 62269 - Draft Tribal Protocol Manual and Scoping for Proposed Policy Statement

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-12

.... The NRC is committed to an open and collaborative regulatory environment in the development of its... NRC also seeks suggestions on the development of the proposed tribal consultation policy statement... uranium recovery development and new nuclear reactor construction has resulted in a significant increase...

10 CFR 7.21 - Cost of duplication of documents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Cost of duplication of documents. 7.21 Section 7.21 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.21 Cost of duplication of documents. Copies of the records, reports, transcripts, minutes, appendices, working papers, drafts, studies, agenda, or other...

10 CFR 7.21 - Cost of duplication of documents.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Cost of duplication of documents. 7.21 Section 7.21 Energy NUCLEAR REGULATORY COMMISSION ADVISORY COMMITTEES § 7.21 Cost of duplication of documents. Copies of the records, reports, transcripts, minutes, appendices, working papers, drafts, studies, agenda, or other...

78 FR 36698 - Microbiology Devices; Reclassification of Nucleic Acid-Based Systems for Mycobacterium tuberculosis

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-19

... specimens from class III (premarket approval) into class II (special controls). FDA is also issuing the draft special controls guideline entitled ``Class II Special Controls Guideline: Nucleic Acid-Based In... regulatory controls needed to provide reasonable assurance of their safety and effectiveness. The three...

78 FR 48504 - Proposed Revisions to Maintenance Rule Standard Review Plan

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

... Review Plan AGENCY: Nuclear Regulatory Commission. ACTION: Standard review plan-draft section revision... Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants: LWR Edition,'' Section 17... and Management System (ADAMS): You may access publicly available documents online in the NRC Library...

78 FR 41434 - Proposed Revisions to Design of Structures, Components, Equipment and Systems

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-10

..., Components, Equipment and Systems AGENCY: Nuclear Regulatory Commission. ACTION: Standard review plan-draft... Systems, Piping Components and their Associated Supports,'' of NUREG-0800, ``Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants: LWR Edition.'' DATES: Submit comments by...

78 FR 310 - Draft Revision of Guidance for Industry on Providing Regulatory Submissions in Electronic Format...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-03

...ApprovalProcess/FormsSubmissionRequirements/ElectronicSubmissions/ucm253101.htm , http://www.regulations.../Drugs/DevelopmentApprovalProcess/FormsSubmissionRequirements/ElectronicSubmissions/ucm253101.htm , http...), in a format that FDA can process, review, and archive. Currently, the Agency can process, review, and...

Unsteady numerical simulation of the flow in the U9 Kaplan turbine model

NASA Astrophysics Data System (ADS)

Javadi, Ardalan; Nilsson, Håkan

2014-03-01

The Reynolds-averaged Navier-Stokes equations with the RNG k-ε turbulence model closure are utilized to simulate the unsteady turbulent flow throughout the whole flow passage of the U9 Kaplan turbine model. The U9 Kaplan turbine model comprises 20 stationary guide vanes and 6 rotating blades (696.3 RPM), working at best efficiency load (0.71 m3/s). The computations are conducted using a general finite volume method, using the OpenFOAM CFD code. A dynamic mesh is used together with a sliding GGI interface to include the effect of the rotating runner. The clearance is included in the guide vane. The hub and tip clearances are also included in the runner. An analysis is conducted of the unsteady behavior of the flow field, the pressure fluctuation in the draft tube, and the coherent structures of the flow. The tangential and axial velocity distributions at three sections in the draft tube are compared against LDV measurements. The numerical result is in reasonable agreement with the experimental data, and the important flow physics close to the hub in the draft tube is captured. The hub and tip vortices and an on-axis forced vortex are captured. The numerical results show that the frequency of the forced vortex in 1/5 of the runner rotation.

Perspective for the development of companion diagnostics and regulatory landscape to encourage personalized medicine in Japan.

PubMed

Tazawa, Yoshiaki

2016-01-01

On July 1st, 2013, the Ministry of Health, Labor and Welfare (MHLW) issued an official notification regarding the co-development of companion diagnostics (CDx) with a drug which requires any exclusive diagnostic test or medical device to predict efficacy or adverse reactions to the drug. The main frame and contents in the MHLW's notification are quite similar to the summaries in the final guidance issued by the US Food and Drug Administration (FDA) on August 6th, 2014 Guidance for Industry and Food and Drug Administration Staff (In Vitro Companion Diagnostic Devices, [2014] ), and these recommend industries to develop, study and submit CDx and the corresponding drug contemporaneously as much as possible. Following the MHLW's notification, the Pharmaceutical and Medical Device Agency (PMDA) notified on December 26th, 2013, "the technical guidance for co-development of CDx and the drug" that mentioned the regulatory requirements for clinical trial of the drug and CDx as well as analytical validity of CDx required for the trials. These official notifications from the Ministry and the Agency may be useful for pharmaceutical and diagnostics makers to understand how they should co-develop and validate CDx for clinical trials and regulatory submission. However, since the most anticipated technologies such as the next generation sequencer (NGS) are more complex and its medical risks could be high level, the existing regulatory system focusing on only diagnostics reagents and devices that are developed and manufactured by in vitro diagnostics (IVD) makers may be no longer suitable for the characteristics of CDx for the future.As an increase of clinical needs for multiple biomarkers assay by DNA sequencer, on November 19th, 2013, the FDA cleared 510 K for NGS and its universal kit. On October 3rd, 2014, moreover, the agency notified two drafts of guidance (Anticipated Details of the Draft Guidance for Industry, Food and Drug Administration Staff, and Clinical Laboratory in Framework for Regulatory Oversight of Laboratory Developed Tests (LDTs), [2014]; Anticipated Details of the Draft Guidance for Industry, Food and Drug Administration Staff, and Clinical Laboratory in FDA Notification and Medical Device Reporting for Laboratory Developed Tests (LDT), [2014]) for oversight of laboratory developed tests (LDTs) with medium or high medical risks. These FDA's strategic decisions and new regulatory frameworks may allow the clinical laboratories to develop and perform more easily NGS-based CDx under the certification of Clinical Laboratory Improvement Amendments (CLIA). However, neither law nor regulated quality management system similar to the CLIA exists in Japan. To effectively validate LDTs and NGS for medical practice, Japan should learn more the current regulatory changes and initiatives in the US, as well as to reform the regulatory frameworks and create any regulated quality management system for clinical laboratory testing to be reimbursed.

75 FR 32834 - U.S. Department of State Advisory Committee on Private International Law Study Group Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-09

... Intellectual Property (IP) The Department of State, Office of the Legal Adviser, Private International Law and... IP licensing guide. The meeting will take place on Thursday, June 17, 2010 from 2:30 p.m. to 4 p.m... in New York (A/CN.9/689), as well as the draft text of the IP supplement to the Guide (A/CN.9/700 and...

Curriculum Guide for Spanish Language Arts, Elementary Level G. Field Test, Working Draft = Guia para la ensenanza de las artes del lenguaje expanol, nivel elemental primario G. Edicion experimental.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The curriculum guide for teachers of Spanish language arts for native Spanish-speaking primary students in the Chicago public schools' bilingual education program is introduced by a section outlining the program and defining the areas to be emphasized in the program: word attack, comprehension skills, study skills, and literature appreciation.…

Curriculum Guide for Spanish Language Arts, Elementary Level H. Field Test, Working Draft = Guia para la ensenanza de las artes del lenguaje espanol, nivel elemental primario H. Edicion experimental.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The curriculum guide for teachers of Spanish language arts for native Spanish-speaking primary students in the Chicago public schools' bilingual education program is introduced by a section outlining the program and defining the areas to be emphasized in the program: word attack, comprehension skills, study skills, and literature appreciation.…

Mathematics Curriculum Guide for Serbocroatian-Speaking Students, Levels A, B, C, Field Test. Working Draft = Uputstvo Za Planiranje Nastave Matematike Za Ucenike koji Govore Srpskohrvatski Jezik, Stepeni A, B, C.

ERIC Educational Resources Information Center

Chicago Board of Education, IL. Dept. of Curriculum.

The introductory level curriculum guide for bilingual education for Serbocroatian-speaking children in the Chicago public schools is divided into three difficulty levels and is designed to facilitate acquisition of mathematical concepts by presenting them in the children's native language. At each level, the concepts covered include the meaning of…

76 FR 35922 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-20

... CONTACT: Harriet Karagiannis, Regulatory Guide Development Branch, Division of Engineering, Office of... direct the use of individual monitoring devices. In addition, 10 CFR part 34, ``Licenses for Industrial Radiography and Radiation Safety Requirements for Industrial Radiographic Operations,'' includes a specific...

77 FR 40921 - Communication With Transport Vehicles

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-11

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0163] Communication With Transport Vehicles AGENCY... Transport Vehicles,'' published in May 1975. The guide is being withdrawn because it is outdated due to... withdrawing Regulatory Guide 5.32, revision 1, ``Communication with Transport Vehicles,'' published in May...

Guide for health professionals addressing oral care for individuals in oncological treatment based on scientific evidence.

PubMed

Carvalho, Caroline Gomes; Medeiros-Filho, João Batista; Ferreira, Meire Coelho

2018-02-22

Oncological treatment can cause changes in the oral cavity compromising oral functions. The aim of the study was, based on a systematic review, to draft a guide directed at the team of health professionals involved in the oral care of oncological patients. A systematic search of the literature was performed for articles published between 2000 and April 2017. Searches were made of electronic databases and hand search. The inclusion criteria were systematic reviews of randomized clinical trials (RCTs) and RCTs published in English, involving pediatric and adult oncological patients and focused on the prevention and treatment of oral complications as well as studies addressing the maintenance of oral health. Among the 1237 studies identified, 129 were pre-selected and 54 were selected to form the basis for the clinical guide. The studies analyzed stress the need for oral assessments as well as preventive and curative actions prior to oncological treatment. To minimize the severity of oral problems, the studies emphasize daily oral care, the treatment of xerostomia with saliva substitute and hydration, and low-level laser therapy, nystatin, acyclovir, respectively, for the prevention and treatment of oral mucositis, oral candidiasis, and infection by herpes simplex virus. Thus, the guide produced addresses oral assessments and professional and home care before, during, and after oncological treatment. The guide drafted has the function of assisting health professionals involved in the oral care of patients with cancer, enabling the prevention or treatment of oral complications stemming from oncological treatment.

78 FR 47272 - Monsanto Co.; Availability of Plant Pest Risk Assessment and Environmental Assessment for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-05

... prepared a draft EA in which we present two alternatives based on our analysis of data submitted by... your comment to Docket No. APHIS-2012-0020, Regulatory Analysis and Development, PPD, APHIS, Station 3A... CONTACT: Dr. Rebecca Stankiewicz Gabel, Chief, Biotechnology Environmental Analysis Branch, Environmental...

76 FR 57006 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; NRC Regulation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

... amended its regulations to include jurisdiction over discrete sources of radium-226, accelerator-produced radioactive materials, and discrete sources of naturally occurring radioactive material, as required by the... those discrete sources of radium-226 under military control that are subject to NRC regulation, as...

78 FR 31922 - National Environmental Justice Advisory Council; Notification of Public Teleconference Meeting...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-28

... draft Technical Guidance for Assessing Environmental Justice in Regulatory Analysis. There will be a... public comment period, or to submit written public comments, is also Noon, Monday, June 10, 2013. DATES... like to be put on the list to provide public comment, and whether you are submitting written comments...

78 FR 16849 - Fall Creek Hydro, LLC, Oregon; Notice of Availability of Draft Environmental Assessment

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-19

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [ Project No. 12778-004] Fall Creek... Office of Energy Projects has reviewed the application for an original license to construct the Fall...-megawatt project would be located on Fall Creek in Lane County, Oregon, near the towns of Springfield and...

77 FR 27055 - National and Governmental Advisory Committees to the U.S. Representative to the Commission for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-08

... authorized under Articles 17 and 18 of the North American Agreement on Environmental Cooperation (NAAEC... strategic, scientific, technological, regulatory, and economic issues related to implementation and further... addressing the draft Guidelines for Submissions on Enforcement Matters under Articles 14 and 15 of the NAAEC...

76 FR 34007 - Draft Regulatory Basis for a Potential Rulemaking on Spent Nuclear Fuel Reprocessing Facilities

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-10

... processes are more akin to fuel cycle processes. This framework was established in the 1970's to license the... nuclear power globally and close the nuclear fuel cycle through reprocessing spent fuel and deploying fast... Accounting;'' and a Nuclear Energy Institute white [[Page 34009

78 FR 56621 - Draft Waste Confidence Generic Environmental Impact Statement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-13

.../public-involve/public-meetings/index.cfm no later than 10 days prior to the meetings. Dated at Rockville... licensed life for operation and prior to ultimate disposal (proposed Waste Confidence rule). The NRC staff... confirming receipt, then contact us at 301-415-1677. Fax comments to: Secretary, U.S. Nuclear Regulatory...

76 FR 75551 - Draft Guidance for Industry on Regulatory Classification of Pharmaceutical Co-Crystals; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-02

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0800... AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA... Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, rm. 2201, Silver Spring, MD...

76 FR 18212 - FPL Energy Maine Hydro LLC; Madison Paper Industries; Merimil Limited Partnership; Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2615-037] FPL Energy Maine Hydro LLC; Madison Paper Industries; Merimil Limited Partnership; Notice of Availability of Draft... paper-filed. To paper-file, mail an original and seven copies to: Kimberly D. Bose, Secretary, Federal...

77 FR 21782 - International Conference on Harmonisation; Draft Guidance for Industry on E2C(R2) Periodic...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

... electronic submission of individual case safety reports to regulatory authorities, automated data mining... Safety Data Management: Periodic Safety Update Reports for Marketed Drugs'' (E2C guidance) and ``Addendum to E2C Clinical Safety Data Management: Periodic Safety Update Reports for Marketed Drugs'' (addendum...

76 FR 18750 - Ocean Renewable Power Company, LLC; Notice of Change in Docket Number

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 12680-003; Project No. 12711-003] Ocean Renewable Power Company, LLC; Notice of Change in Docket Number On July 24, 2009, Ocean Renewable Power Company, LLC (ORPC) filed a draft hydrokinetic pilot license application (DLA) for the...

78 FR 663 - Decommissioning Planning During Operations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-04

...] Decommissioning Planning During Operations AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide..., ``Decommissioning Planning During Operations.'' The guide describes a method that the NRC staff considers acceptable for use by holders of licenses in complying with the NRC's Decommissioning Planning Rule (DPR) (76 FR...

Supporting Research and Technology Activities for a Microwave Observing Program to Search for Extraterrestrial Intelligence

NASA Technical Reports Server (NTRS)

Tarter, Jill; Backus, Peter

1995-01-01

Curriculum materials based on the search for extraterrestrial intelligence (SETI) were developed for grades 3 through 9 science classes. The project was supported in part by NASA. Six teacher's guides, plus ancillary visuals, addressing topics in astronomy, biology, chemistry, geosciences, and physics as well as mathematics, social sciences, and language arts, were designed by a team of teachers, scientists. curriculum developers, and artists. First drafts were piloted by 10 design team teachers; revised drafts were field tested by 109 teachers in 30 states. Extensive feedback from these teachers and their students and reviews by scientists were used to revise materials prior to submission to the publisher. The field test teachers overall ranking of all guides (data from individual lesson feedback forms) was 431 on a one low to five high scale; 85% found the content appropriate to course and grade level and 75% indicated they had no reservations about using the materials again or recommending them to colleagues. The ratio of liked to disliked student responses (from 1305 student letters) was 70:30. Most recommendations from the teachers, students, and science reviewers were incorporated in the final versions for the guides, published by Libraries Unlimited/Teacher Ideas Press, 1995.

Development of a hydro kinetic river turbine with simulation and operational measurement results in comparison

NASA Astrophysics Data System (ADS)

Ruopp, A.; Ruprecht, A.; Riedelbauch, S.; Arnaud, G.; Hamad, I.

2014-03-01

The development of a hydro-kinetic prototype was shown including the compound structure, guide vanes, runner blades and a draft tube section with a steeply sloping, short spoiler. The design process of the hydrodynamic layout was split into three major steps. First the compound and the draft tube section was designed and the best operating point was identified using porous media as replacement for the guide vane and runner section (step one). The best operating point and the volume flux as well as the pressure drop was identified and used for the design of the guide vane section and the runner section. Both were designed and simulated independently (step two). In step three, all parts were merged in stationary simulation runs detecting peak power and operational bandwidth. In addition, the full scale demonstrator was installed in August 2010 and measured in the St. Lawrence River in Quebec supporting the average inflow velocity using ADCP (Acoustic Doppler Current Profiler) and the generator power output over the variable rotational speed. Simulation data and measurements are in good agreement. Thus, the presented approach is a suitable way in designing a hydro kinetic turbine.

75 FR 79049 - Final Regulatory Guide: Issuance, Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-17

... (RG) 5.80, ``Pressure-Sensitive and Tamper-Indicating Device Seals for Material Control and Accounting... and licenses. Regulatory Guide 5.80, ``Pressure-Sensitive and Tamper-Indicating Device Seals for... and Use of Pressure-Sensitive Seals on Containers for Onsite Storage of Special Nuclear Material...

75 FR 62436 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-08

... Power Plants,'' includes in its scope safety- related structures, systems, and components (SSCs) that... monitor the effectiveness of maintenance for protective coatings within its scope (as discrete systems or... and Management System (ADAMS) under Accession No. ML102230359. Electronic copies of Regulatory Guide 1...

75 FR 54921 - Withdrawal of Regulatory Guides 1.38, 1.94, and 1.116

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-09

....116, ``Quality Assurance Requirements for Installation, Inspection, and Testing of Mechanical....116, ``Quality Assurance Requirements for Installation, Inspection, and Testing of Mechanical Equipment and Systems,'' dated May 1977. Regulatory Guide 1.38 endorses the American Society of Mechanical...

77 FR 18871 - Administrative Guide for Verifying Compliance With Packaging Requirements for Shipment and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-28

... Packaging Requirements for Shipment and Receipt of Radioactive Material AGENCY: Nuclear Regulatory... with Packaging Requirements for Shipment and Receipt of Radioactive Material.'' This regulatory guide... for transporting licensed material under 10 CFR part 71, ``Packaging and Transportation of Radioactive...

Health Assessment Document for Diesel Exhaust (Revised ...

EPA Pesticide Factsheets

This External Review Draft version of this assessment updates three earlier drafts (1999, 1998 and 1994) that were reviewed by the Clean Air Scientific Advisory Committee (CASAC) of the Agency's Science Advisory Board (SAB). The assessment characterizes the possible human health hazards and related exposure-response aspects of those hazards related to environmental exposure to diesel exhaust. The final assessment will incorporate peer review comments provided by the CASAC in 2000 and will take acount of public comments received during the public review period. This is a health hazard assessment. The purpose of the assessment is to identify the key health hazards associated with environmental exposure to diesel exhaust. Information from earlier draft versions of this assessment were used to support EPA regulatory decision making about emission controls for On Road Heavy Duty Diesel Engines and Off Road Diesel Engine Emissions. Also information from the assessment contributes to a nationwide analysis of air toxics to determine the highest public health priorities for future air pollution control programs.

78 FR 64030 - Monitoring Criteria and Methods To Calculate Occupational Radiation Doses

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0234] Monitoring Criteria and Methods To Calculate... regulatory guide (DG), DG-8031, ``Monitoring Criteria and Methods to Calculate Occupational Radiation Doses.'' This guide describes methods that the NRC staff considers acceptable for licensees to use to determine...

76 FR 46856 - Qualification of Connection Assemblies for Nuclear Power Plants

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-03

... Power Plants AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide; issuance. SUMMARY: The U.S..., ``Qualification of Connection Assemblies for Nuclear Power Plants.'' This guide describes a method that the NRC... in nuclear power plants. The environmental qualification helps ensure that connection assemblies can...

76 FR 65541 - Assuring the Availability of Funds for Decommissioning Nuclear Reactors

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-21

... NUCLEAR REGULATORY COMMISSION [NRC-2009-0263] Assuring the Availability of Funds for Decommissioning Nuclear Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide; issuance. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC or Commission) is issuing a revision to Regulatory...

[The federal participation law : New requirements for needs assessment with special emphasis on medical rehabilitation services].

PubMed

Schubert, Michael; Schian, Marcus; Viehmeier, Sarah

2016-09-01

The federal participation law (Bundesteilhabegesetz - BTHG) is one of the largest efforts in the last 15 years to reform the legal participation rights of people with disabilities. In particular, a number of enhancements are planned in the overall benefits law in Part 1 of Book IX in the Social Code (Sozialgesetzbuch - SGB), which applies to all rehabilitation carriers including general provisions and standards for needs assessment. This paper deals with the implications of these provisions and interacting standards, based on the draft bill of April 2016.The discussion takes place against the background of the regulatory objectives formulated in the ministerial draft itself, jurisprudential expertise on the effects of the current legal norms of the SGB IX as well as relevant professional political developments and statements by various stakeholders.The analysis shows a clear political commitment to increase the requirements for needs assessment in the overall law of the SGB IX and to express these more effectively. The draft bill seeks not only to modify procedures subsequent to the application for rehabilitation benefits, but also to precisely set out provisions on instruments for needs assessment in a new § 13. Common principles for these instruments of needs assessment should increase the cooperation, coordination and convergence among rehabilitation carriers.Nevertheless, with regard to the proposed regulatory texts, there is doubt that the objectives set by the draft bill itself will be achieved. For example, the required common principles for needs assessment are to be agreed upon based on the existing special legislation for the different rehabilitation carriers, without the SGB IX setting its own binding standards or framework principles. In addition, it lacks clear legal guidelines for the professional practice to make use of the bio-psycho-social model of the WHO and the ICF in the process of needs assessment. As a consequence the ICF cannot serve as a legally standardized reference point.

Best Practices for Controlling Lead and Copper Release

EPA Science Inventory

Presentation draft, covering summary of current state-of-the-art knowledge for the best treatment strategies for minimizing lead release and controlling copper release. The presentation is intended to aid with compliance with the Lead and Copper Rule, but also provide a guide to...

75 FR 78268 - Draft NIJ Selection and Application Guide to Ballistic-Resistant Body Armor for Law Enforcement...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-15

... INFORMATION CONTACT: Casandra Robinson, by telephone at 202-305-2596 [Note: this is not a toll-free telephone number], or by e- mail at casandra.robinson@usdoj.gov . Dr. John H. Laub, Director, National Institute of...

75 FR 6737 - FPL Energy Duane Arnold, LLC; Notice of Availability of the Draft Supplement 42 to the Generic...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

... NUCLEAR REGULATORY COMMISSION [Docket No. 50-331; NRC-2010-0048] FPL Energy Duane Arnold, LLC... License Renewal of Nuclear Plants, and Public Meeting for the License Renewal of Duane Arnold Energy... of operation for Duane Arnold Energy Center (DAEC). DAEC is located near Cedar Rapids, Iowa...

75 FR 20008 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-16

... copy of the draft supporting statement may be viewed free of charge at the NRC Public Document Room... and search for Docket No. NRC-2010-0153. Mail comments to NRC Clearance Officer, Tremaine Donnell (T-5.... Nuclear Regulatory Commission, Washington, DC 20555-0001, by telephone at 301- 415-6258, or by e-mail to...

75 FR 82413 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-30

... technology? A copy of the draft supporting statement may be viewed free of charge at the NRC Public Document... and search for Docket No. NRC-2010-0347. Mail comments to NRC Clearance Officer, Tremaine Donnell (T-5.... Nuclear Regulatory Commission, Washington, DC 20555-0001, by telephone at 301- 415-6258, or by e-mail to...

75 FR 44816 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-29

... copy of the draft supporting statement may be viewed free of charge at the NRC Public Document Room... and search for Docket No. NRC-2010-0261. Mail comments to NRC Clearance Officer, Tremaine Donnell (T-5.... Nuclear Regulatory Commission, Washington, DC 20555-0001, by telephone at 301-415-6258, or by e-mail to...

The U.S. draft guidance regarding population and individual bioequivalence approaches: comments by a research-based pharmaceutical company.

PubMed

Hauschke, D; Steinijans, V W

2000-10-30

Generally, the motivation for switching from average bioequivalence to population and/or individual bio-equivalence is well recognized in the light of certain limitations of the concept of average bioequivalence. However, this switch still results in unresolved issues which should be addressed before the regulatory guidance is finalized.

78 FR 46925 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Snapper-Grouper Fishery off the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-02

... preparation of a draft environmental impact statement (EIS) to an EA for Regulatory Amendment 14. FOR FURTHER... of No Significant Impact (FONSI), the EA and FONSI will be the final environmental documents required by NEPA. If the EA reveals that significant environmental impacts may be reasonably expected to...

76 FR 2924 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; Adequacy of Station...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-18

... positions. No specific action or written response is required. DATES: Comment period expires 30 days after... new requirements or staff positions. No specific action or written response is required. Background... on the operation of Class 1E loads. These degraded voltage conditions will not be detected by the...

75 FR 38958 - Declaration of Prion as a Pest under FIFRA and Amendment of EPA's Regulatory Definition of Pests...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-07

... Human Services with a copy of any draft proposed rule pertaining to a public health pesticide at least...; Notification to the Secretaries of Agriculture and Health and Human Services AGENCY: Environmental Protection Agency (EPA). ACTION: Notification to the Secretaries of Agriculture and Health and Human Services...

76 FR 40282 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; NRC Regulation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-08

... Commission (NRC) is proposing to issue a RIS that clarifies those discrete sources of radium-226 under... Officers. Intent The NRC is issuing this RIS to clarify which discrete sources of radium-226 under military... definition of byproduct material to include discrete sources of radium-226, discrete sources of naturally...

76 FR 23513 - Public and Closed Meeting To Discuss Comments on Draft Regulatory Basis for Rulemaking Revising...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-27

..., ``Security Performance (Adversary) Characteristics for Physical Security Programs for 10 CFR [Title 10 of the..., ``Physical Protection of Plants and Materials,'' that would apply during the storage of SNF at an ISFSI and... facilities licensed to store SNF through a combination of these existing security regulations and the...

77 FR 16990 - Notification of Submission to the Secretary of Agriculture of Two Draft Regulatory Documents...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-23

... and Applicability; Clarification and Availability of Test Guideline''; and the second is entitled... Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA. The Docket Facility is open from 8:30 a.m. to 4...) 305-5805. FOR FURTHER INFORMATION CONTACT: Rose Kyprianou, Field and External Affairs Division (7506P...

77 FR 24611 - Removal of Regulations Requiring 3% Withholding by Government Entities

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-25

.... Approved: April 17, 2012. Emily S. McMahon, Acting Assistant Secretary of the Treasury (Tax Policy). [FR... determined that section 553(b) of the Administrative Procedure Act (5 U.S.C. chapter 5) does not apply to... Regulatory Flexibility Act (5 U.S.C. chapter 6) does not apply. Drafting Information The principal author of...

75 FR 26956 - Draft Toxicological Review of Hexachloroethane: In Support of the Summary Information in the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-13

... science-based human health assessments to support the Agency's regulatory activities. The IRIS database... May 21, 2009, to develop human health assessments for inclusion in the IRIS database. The purpose of... if you will need audio-visual aid (e.g., lap top computer and slide projector). In general, each...

75 FR 21368 - South Carolina Electric and Gas Acting for Itself and as an Agent for South Carolina Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-23

... NUCLEAR REGULATORY COMMISSION [Docket No. 52-027 and 52-028; NRC-2008-0441] South Carolina Electric and Gas Acting for Itself and as an Agent for South Carolina Public Service Authority (Also Referred to as Santee Cooper) Notice of Availability of the Draft Environmental Impact Statement for the...

78 FR 63517 - Control of Ferrite Content in Stainless Steel Weld Metal

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

...The U.S. Nuclear Regulatory Commission (NRC) is issuing a revision to Regulatory Guide (RG) 1.31, ``Control of Ferrite Content in Stainless Steel Weld Metal.'' This guide (Revision 4) describes a method that the NRC staff considers acceptable for controlling ferrite content in stainless steel weld metal. It updates the guide to remove references to outdated standards and to remove an appendix that has been incorporated into relevant specifications.

Regulatory facility guide for Ohio

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, S.S.; Bock, R.E.; Francis, M.W.

1994-02-28

The Regulatory Facility Guide (RFG) has been developed for the DOE and contractor facilities located in the state of Ohio. It provides detailed compilations of international, federal, and state transportation-related regulations applicable to shipments originating at destined to Ohio facilities. This RFG was developed as an additional resource tool for use both by traffic managers who must ensure that transportation operations are in full compliance with all applicable regulatory requirements and by oversight personnel who must verify compliance activities.

Quality Management Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-10-01

According to {section} 35.32, Quality Management Program,'' of 10 CFR Part 35, Medical Use of Byproduct Material,'' applicants or licensees, as applicable, are required to establish a quality management (QM) program. This regulatory guide provides guidance to licensees and applicants for developing policies and procedures for the QM program. This guide does not restrict or limit the licensee from using other guidance that may be equally useful in developing a QM program, e.g., information available from the Joint Commission on Accreditation of Healthcare Organizations or the American College of Radiology. Any information collection activities mentioned in this regulatory guide aremore » contained as requirements in 10 CFR Part 35, which provides the regulatory basis for this guide. This information collection requirements in 10 CFR Part 35 have been cleared under OMB Clearance No. 3150-0010.« less

Total Quality Management Guide. A Two Volume Guide for Defense Organizations. Volume 1. Key Features of the DoD Implementation

DTIC Science & Technology

1990-02-15

XIALTM DoD 5000.51-G A * FINAL DRAFT 2/15/90 si- N ~LUM I -KY FEATRES OFTHE Do IMLEENAON TOTAL L/ De~rrn QUADefens FOREWORD Government and industry...away with all government inspectors. Rather. government oversight will change from te large scale product inspection and specifying the -how to...in class" - Set the course for the future, and - Provide a baseline for measuring progress. Benchmarking is a continuous process of comparing an

75 FR 79049 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-17

..., Division of Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission... INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC) is issuing a revision to an existing... Development Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc. 2010-31731 Filed...

Corridor-based planning tool for transportation of wind turbine components : manual guide : preliminary draft.

DOT National Transportation Integrated Search

2016-08-01

The enclosed report describes 0-6850-P1, a stand-alone planning tool that can be : used to propose a route plan for wind turbine components passing along Texas routes. : The report provides instructions on how to use the tool.

Department of Defense Intelligence Information System (DoDIIS). Instructions 2000

DTIC Science & Technology

2000-02-01

DIA, November 1993, DoDIIS Site Certifier’s Guide, SC-2610-143-93. e) DIA, June 1995, DoDIIS Security Architecture Guidance and Directions ( SAGD ), Draft...Plan S&T Scientific & Technical SAGD Security Architecture Guidance and Directions SBU Sensitive But Unclassified SCI Sensitive Compartmented

Fact Sheet: A Technical Guide to Ground-Water Model Selection at Sites Contaminated with Radioactive Substances

EPA Pesticide Factsheets

This fact sheet summarizes the findings of a report drafted by a joint Interagency Environmental Pathway Modeling Working Group. It is to be used by technical staff responsible for implementing flow and transport models to support cleanup decisions.

Revisiting Metacognition and Metaliteracy in the ACRL Framework

ERIC Educational Resources Information Center

Fulkerson, Diane M.; Ariew, Susan Andriette; Jacobson, Trudi E.

2017-01-01

In the early drafts of the "Information Literacy Framework for Higher Education," metaliteracy and metacognition contributed several guiding principles in recognition of the fact that information literacy concepts need to reflect students' roles as creators and participants in research and scholarship. The authors contend that diminution…

77 FR 24228 - Condition Monitoring Techniques for Electric Cables Used in Nuclear Power Plants

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-23

... Used in Nuclear Power Plants AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide; issuance... guide, (RG) 1.218, ``Condition Monitoring Techniques for Electric Cables Used in Nuclear Power Plants... of electric cables for nuclear power plants. RG 1.218 is not intended to be prescriptive, instead it...

77 FR 40385 - Withdrawal of Regulatory Guide 7.3; Procedures for Picking Up and Receiving Packages of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-09

... Picking Up and Receiving Packages of Radioactive Material AGENCY: Nuclear Regulatory Commission. ACTION... Receiving Packages of Radioactive Material.'' The RG is being withdrawn because it is outdated and the..., ``Administrative Guide for Verifying Compliance with Packaging Requirements for Shipment and Receipt of Radioactive...

Next generation and biosimilar monoclonal antibodies

PubMed Central

2011-01-01

The Next Generation and Biosimilar Monoclonal Antibodies: Essential Considerations Towards Regulatory Acceptance in Europe workshop, organized by the European Centre of Regulatory Affairs Freiburg (EUCRAF), was held February 3–4, 2011 in Freiburg, Germany. The workshop attracted over 100 attendees from 15 countries, including regulators from 11 agencies, who interacted over the course of two days. The speakers presented their authoritative views on monoclonal antibodies (mAbs) as attractive targets for development, the experience to date with the regulatory process for biosimilar medicinal products, the European Medicines Agency draft guideline on biosimilar mAbs, as well as key elements in the development of mAbs. Participants engaged in many lively discussions, and much speculation on the nature of the quality, non-clinical and clinical requirements for authorization of biosimilar mAbs. PMID:21487235

Clothing and Textiles II. Semester Course. Draft.

ERIC Educational Resources Information Center

Blanton, Harriet; And Others

The clothing and textiles guide for a second level semester course for grades 10-12 identifies objectives and learning experiences with basic reference to developmental tasks, needs, interests, capacities, and prior learning experiences of students. It was developed for use with students who exhibited skill and a high degree of satisfaction from…

A Comprehensive Horticulture Curriculum Guide for New Jersey Schools.

ERIC Educational Resources Information Center

Rutgers, The State Univ., New Brunswick, NJ. Cook Coll.

A horticultural core curriculum and draft copies of three horticultural cluster curricula are provided. Materials related to the curriculum development project appear first. The core curriculum is designed to provide broad initial instruction in horticulture for students in the first year of a secondary-level vocational horticulture program. The…

A Manual for Small Libraries in Alaska.

ERIC Educational Resources Information Center

Kolb, Audrey

Intended as a guide and resource for staff and volunteers in small public libraries in Alaska, this manual is divided into the following chapters: (1) "Establishing a Library," which covers the establishment by ordinance or by organization of a non-profit corporation, information on drafting bylaws, and the role and responsibilities of…

76 FR 13410 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-11

... and their culture of patient safety. This survey is designed for use in community/retail pharmacies... on Patient Safety Culture Questionnaire; (2) Pretest and modify the questionnaire as necessary; (3... interview guide will be used for each round. (2) Pretest--The draft questionnaire will be pretested with all...

They All Have Something To Say: Helping Learning Disabled Students Write.

ERIC Educational Resources Information Center

Schwartz, Shirley S.; MacArthur, Charles A.

1990-01-01

A process approach to writing instruction with learning-disabled students is presented, in which students are guided through the processes of planning, drafting, and revising text. The model emphasizes the interaction of the teacher and learner through such activities as conferences, prompting, modeling, peer collaboration, and dialogues about…

78 FR 57860 - Draft NIH Genomic Data Sharing Policy Request for Public Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-20

... underlying disease, development of statistical research methods, the study of populations origins). If so... community will be notified through appropriate communication methods (e.g., The NIH Guide for Grants and... Sharing Policy Request for Public Comments SUMMARY: The National Institutes of Health (NIH) is seeking...

LABORATORY INVOLVEMENT IN PLANNING FOR AND RESPONDING TO CONTAMINATION THREATS TO DRINKING WATER SYSTEMS

EPA Science Inventory

EPA's National Homeland Security Research Center (Office of Research and Development) and Water Protection Task Force (Office of Water) have jointly developed a draft analytical guide that may be used by laboratories to plan for and provide support to a drinking water utility...

Shemya Air Force Base, Alaska No Further Action Decision document for Hg-1. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-03-05

This document is being prepared to document that a No Further Action Decision (NFAD) document is appropriate for the Hg-1 site at Shemya Air Force Base (AFB), Alaska, under the Air Force Installation Restoration Program (IRP). The IRP is a Department of Defense (DOD) program established to identify and remediate hazardous waste problems on DOD property that result from past practices. The Alaska Department of Environmental Conservation (ADEC) draft document {open_quotes}No Further Action Criteria for DOD Military/FUD Sites{close_quotes} has been used as a guide in preparing this document. Air Force personnel have stated that the Hg-1 site may have beenmore » used to store mercury and PCB-contaminated material. The site was added to the IRP in 1987, and later that year a field investigation was conducted at the site. Soil samples were collected and analyzed for mercury, EP toxicity, polychlorinated biphenyls (PCBs), and dioxin. All concentrations of contaminants found in Area Hg-1 are below regulatory action levels for PCBs (40 CFR 761) and mercury (55 FR 30798) or below detection levels for dioxin/furans. Therefore, leaving these soils in place is acceptable.« less

Shemya Air Force Base, Alaska No Further Action Decision document for Hg-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-03-05

This document is being prepared to document that a No Further Action Decision (NFAD) document is appropriate for the Hg-1 site at Shemya Air Force Base (AFB), Alaska, under the Air Force Installation Restoration Program (IRP). The IRP is a Department of Defense (DOD) program established to identify and remediate hazardous waste problems on DOD property that result from past practices. The Alaska Department of Environmental Conservation (ADEC) draft document [open quotes]No Further Action Criteria for DOD Military/FUD Sites[close quotes] has been used as a guide in preparing this document. Air Force personnel have stated that the Hg-1 site maymore » have been used to store mercury and PCB-contaminated material. The site was added to the IRP in 1987, and later that year a field investigation was conducted at the site. Soil samples were collected and analyzed for mercury, EP toxicity, polychlorinated biphenyls (PCBs), and dioxin. All concentrations of contaminants found in Area Hg-1 are below regulatory action levels for PCBs (40 CFR 761) and mercury (55 FR 30798) or below detection levels for dioxin/furans. Therefore, leaving these soils in place is acceptable.« less

76 FR 10072 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX, Adequacy of Station...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-23

... electronic form will be posted on the NRC Web site and on the Federal Rulemaking Web site Regulations.gov... that they do not want publicly disclosed. Federal rulemaking Web site: Go to http://www.regulations.gov... through this Web site. Address questions about NRC dockets to Carol Gallagher, telephone: 301-492-3668, e...

75 FR 19969 - Science Advisory Board Staff Office; Notification of a Public Meeting of the Advisory Council on...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-16

... Office of Air and Radiation's Second Section 812 Prospective Analysis of the benefits and costs of the... review draft EPA documents prepared for the Second Section 812 Prospective Benefit-Cost Analysis of the... studies to assess benefits and costs of the EPA's regulatory actions under the Clean Air Act. The Council...

76 FR 11522 - Nuclear Innovation North America LLC; Notice of Availability of the Final Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-02

... Regulatory Commission (NRC) and the U.S. Army Corps of Engineers as a cooperating agency have published a... Licenses (COLs) at the South Texas Project Electric Generating Station Units 3 and 4: Final Report'' for the South Texas Project Electric Generating Station Units 3 and 4 COL application. The draft EIS was...

10 CFR 8.5 - Interpretation by the General Counsel of § 73.55 of this chapter; illumination and physical...

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Interpretation by the General Counsel of § 73.55 of this chapter; illumination and physical search requirements. 8.5 Section 8.5 Energy NUCLEAR REGULATORY... 0220, Draft Interim Acceptance Criteria for a Physical Security Plan for Nuclear Power Plants (March...

10 CFR 8.5 - Interpretation by the General Counsel of § 73.55 of this chapter; illumination and physical...

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Interpretation by the General Counsel of § 73.55 of this chapter; illumination and physical search requirements. 8.5 Section 8.5 Energy NUCLEAR REGULATORY... 0220, Draft Interim Acceptance Criteria for a Physical Security Plan for Nuclear Power Plants (March...

10 CFR 8.5 - Interpretation by the General Counsel of § 73.55 of this chapter; illumination and physical...

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Interpretation by the General Counsel of § 73.55 of this chapter; illumination and physical search requirements. 8.5 Section 8.5 Energy NUCLEAR REGULATORY... 0220, Draft Interim Acceptance Criteria for a Physical Security Plan for Nuclear Power Plants (March...

78 FR 40776 - Issuance of Regulatory Guide 1.124 and Regulatory Guide 1.130

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-08

... Limits and Loading Combinations for Class 1 Plate-and- Shell-Type Supports.'' There are no substantive... 1 linear-type component and piping supports, and Class 1 plate-and-shell-type component and piping... Rulemaking Web site: Go to http://www.regulations.gov and search for Docket ID NRC-2013-0141. Address...

76 FR 14107 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-15

... INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC or Commission) is issuing a revision... Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc. 2011-5967 Filed 3-14-11...

78 FR 38739 - Standard Format and Content for Post-Shutdown Decommissioning Activities Report

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-27

...The U.S. Nuclear Regulatory Commission (NRC) is issuing Revision 1 of Regulatory Guide (RG) 1.185, ``Standard Format and Content for Post-shutdown Decommissioning Activities Report.'' This guide describes a method that the NRC staff considers acceptable for use in complying with the Commission's requirements regarding the submission of a post-shutdown decommissioning activities report (PSDAR).

Regulatory perspective on remaining challenges for utilization of pharmacogenomics-guided drug developments.

PubMed

Otsubo, Yasuto; Ishiguro, Akihiro; Uyama, Yoshiaki

2013-01-01

Pharmacogenomics-guided drug development has been implemented in practice in the last decade, resulting in increased labeling of drugs with pharmacogenomic information. However, there are still many challenges remaining in utilizing this process. Here, we describe such remaining challenges from the regulatory perspective, specifically focusing on sample collection, biomarker qualification, ethnic factors, codevelopment of companion diagnostics and means to provide drugs for off-target patients. To improve the situation, it is important to strengthen international harmonization and collaboration among academia, industries and regulatory agencies, followed by the establishment of an international guideline on this topic. Communication with a regulatory agency from an early stage of drug development is also a key to success.

Principles for Promoting the Financial Sustainability of Online Programs

ERIC Educational Resources Information Center

Meyer, Katrina A.; Bruwelheide, Janis; Poulin, Russell

2009-01-01

The project described in this article was an attempt to uncover the principles of financial sustainability for online programs and to align these with a guide to managing online programs. An initial team of experienced online educators developed draft principles, which were then reviewed by an external consultant and revised; the revised…

Industrial Arts 7-9. Graphic Communications. Drafting. Graphic Arts.

ERIC Educational Resources Information Center

Manitoba Dept. of Education, Winnipeg.

This guide for industrial arts grades 7-9 provides teachers with a curriculum for the subject cluster of graphic communications. An "Overview" section presents the rationale, discusses how the content of the program is related to the developmental stages of the adolescent, describes the structure of the industrial arts program, and lists…

TMDD & MS/ETMCC guide : standard for functional level traffic management data dictionary (TMDD) and message sets for external traffic management center communications

DOT National Transportation Integrated Search

2000-01-01

These draft standards are intended to work together to provide a high level of interoperability among regional and local traffic control centers. They provide consistent names, definitions and concepts similar to spelling and parts of speech to world...

Derrick Bell's Post-"Brown" Moves toward Critical Race Theory

ERIC Educational Resources Information Center

Hughes, Sherick; Noblit, George; Cleveland, Darrell

2013-01-01

The late Professor Derrick Bell is renowned as the intellectual architect who drafted the blueprints that guided the initial development of critical race theory (CRT). Prior to the advent of CRT, Professor Bell wrote extensively on initiatives designed to improve the lives of African Americans. Among his most influential scholarship, "Serving…

Unit: Tuning in With Our Senses, Inspection Set, National Trial Print.

ERIC Educational Resources Information Center

Australian Science Education Project, Toorak, Victoria.

A preliminary version of this trial draft of a unit prepared for Australian secondary science students was previously announced as ED 049 931 under the short title of "Messengers." The teachers' guide is an overprinted version of the students' booklet, and lists objectives for each section of the materials, indicates possible teaching…

Early Childhood Standards of Quality for Prekindergarten through Second Grade.

ERIC Educational Resources Information Center

Michigan State Board of Education, Lansing.

Recognizing the value and need for quality early childhood education programs for children ages four through eight years, the Michigan State Board of Education appointed an ad hoc committee to develop standards of quality. Based on the draft developed by this committee, this standards guide is designed to assist administrators, teachers, and…

A Cable TV Guide for Educators: Uses and Provisions. Second Edition.

ERIC Educational Resources Information Center

Shafer, Jon

The primary focus of this monograph is on how school districts might involve themselves in the process of drafting cable television ordinances and granting cable franchises. An introductory section surveys the history of cable television, its educational uses, two-way capabilities, the local origination rule, and the role of the Federal…

World of Work. First Year Report, 1971-1972.

ERIC Educational Resources Information Center

Mount Pleasant Public Schools, MI.

Prepared during the first year of a 3-year pilot program, this working draft of a resource guide represents efforts to develop and field test resource units for career education, Grades 1-6. The units, which include objectives and learning activities, are clustered as follows: (1) Distribution and Marketing, (2) Agriculture-Natural Resources, (3)…

Foreign Languages Course of Study, Junior & Senior High Schools. Draft.

ERIC Educational Resources Information Center

Dade County Public Schools, Miami, FL. Div. of Elementary and Secondary Instruction.

The study guide outlining the modern foreign language courses for English speakers in Dade County's secondary schools establishes a uniform sequential program for instruction in French, German, Hebrew, Italian, and Spanish. Program expectancies are described for each level and type of course, to serve as a basis for planning appropriate…

77 FR 16854 - John Heinz National Wildlife Refuge at Tinicum, Delaware and Philadelphia Counties, PA; Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-22

... urban setting. Visitors to the refuge also participate in wildlife observation, photography, and fishing... observation and photography, and environmental education and interpretation. We will review and update the CCP... focus on providing training for teachers so they could guide field trips on refuge property. Alternative...

77 FR 33243 - Public Comment and Public Meeting on Draft Revisions to the Federal Environment Element of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-05

... Federal Environment Element of the Comprehensive Plan for the National Capital: Federal Elements AGENCY... Environment Element of the Comprehensive Plan for the National Capital: Federal Elements. The Comprehensive... required by law. The Federal Environment Element articulates policies that guide federal actions on...

Standards for School Leaders Get New Thumbs Up

ERIC Educational Resources Information Center

Olson, Lynn

2008-01-01

A coalition of education groups came together in the mid-1990s to draft model standards for school leaders that would refocus the profession on student learning. Since then, the resulting Interstate School Leaders Licensure Consortium standards have been used or adapted by more than 40 states to guide their own preparation, licensure, and…

Drafting 101, 201, 301. Industrial Arts.

ERIC Educational Resources Information Center

Manitoba Dept. of Education, Winnipeg. Div. of Vocational Education.

This curriculum guide outlines three credits of study, one credit for each of the grade levels 10, 11, and 12. Intended as an optional study area, the program provides awareness and exploration for those students who aspire to postsecondary study and introduces skills to those who wish to explore trades and technologies in employment after school.…

A Supplementary Program for Environmental Education, Industrial Arts, Grade 7-12.

ERIC Educational Resources Information Center

Warpinski, Robert

Presented in this teacher's guide for grades 7-12 are lesson plans and ideas for integrating industrial arts (drafting, woodworking, and metals) and environmental education. Each lesson originates with a fundamental concept pertaining to the environment and states, in addition, its discipline area, subject area, and problem orientation. Following…

Effects of Pump-turbine S-shaped Characteristics on Transient Behaviours: Experimental Investigation

NASA Astrophysics Data System (ADS)

Zeng, Wei; Yang, Jiandong; Hu, Jinhong; Tang, Renbo

2017-05-01

A pumped storage stations model was set up and introduced in the previous paper. In the model station, the S-shaped characteristic curves was measured at the load rejection condition with the guide vanes stalling. Load rejection tests where guide-vane closed linearly were performed to validate the effect of the S-shaped characteristics on hydraulic transients. Load rejection experiments with different guide vane closing schemes were also performed to determine a suitable scheme considering the S-shaped characteristics. The condition of one pump turbine rejecting its load after another defined as one-after-another (OAA) load rejection was performed to validate the possibility of S-induced extreme draft tube pressure.

The evolution and challenges for the international harmonization of the regulation of pharmaceutical excipients in Taiwan.

PubMed

Chang, Lin-Chau; Kang, Jaw-Jou; Gau, Churn-Shiouh

2015-12-01

Excipients, once considered an inert component, have been shown to greatly influence the characteristics of the drug product, such as quality and safety. Functionality-related characteristics of excipients could affect the performance of the drug product. Moreover, the impact of globalization has complicated the issue and made the supervision of supply chain highly important. Taiwan, a member of the Pharmaceutical Inspection Convention and Pharmaceutical Inspection Co-operation Scheme, makes efforts to harmonize with international regulations and to strengthen the protection of patients through regulatory controls. In order to improve the harmonization and the transparency of regulatory requirements, the aim of the present study was to investigate the regulatory framework and considerations of stringent regulatory authorities and to propose the draft regulatory requirements to the Taiwan Food and Drug Administration for jurisdiction. The proposal which was extensively discussed in the expert committee includes the regulatory considerations to ensure the safety and quality of the excipients and may serve as a platform to facilitate the communication with industries about the current thinking on related issues. Moreover, through the review of the recent guidelines published by the stringent regulatory authorities, the trend of the regulatory considerations was revealed and discussed. Copyright © 2015 Elsevier Inc. All rights reserved.

A guide to federal-aid programs and projects

DOT National Transportation Integrated Search

1999-05-01

This guide provides basic information about Federal-aid programs, projects, and other program characteristics. The information sheets contained in the guide provide fiscal information, statutory and regulatory references, general eligibility and back...

Runaway transient simulation of a model Kaplan turbine

NASA Astrophysics Data System (ADS)

Liu, S.; Zhou, D.; Liu, D.; Wu, Y.; Nishi, M.

2010-08-01

The runaway transient is a typical transient process of a hydro power unit, where the rotational speed of a turbine runner rapidly increases up to the runaway speed under a working head as the guide vanes cannot be closed due to some reason at the load rejection. In the present paper, the characteristics of the runaway transient of a model Kaplan turbine having ns = 479(m-kW) is simulated by using a time-dependent CFD technique where equation of rotational motion of runner, continuity equation and unsteady RANS equations with RNG k-epsilon turbulence model are solved iteratively. In the calculation, unstructured mesh is used to the whole flow passage, which consists of several sub-domains: entrance, casing, stay vanes + guide vanes, guide section, runner and draft tube. And variable speed sliding mesh technique is used to exchange interface flow information between moving part and stationary part, and three-dimensional unstructured dynamic mesh technique is also adopted to ensure mesh quality. Two cases were treated in the simulation of runaway transient characteristics after load rejection: one is the rated operating condition as the initial condition, and the other is the condition at the maximum head. Regarding the runaway speed, the experimental speed is 1.45 times the initial speed and the calculation is 1.47 times the initial for the former case. In the latter case, the experiment and the calculation are 1.67 times and 1.69 times respectively. From these results, it is recognized that satisfactorily prediction will be possible by using the present numerical method. Further, numerical results show that the swirl in the draft-tube flow becomes stronger in the latter part of the transient process so that a vortex rope will occur in the draft tube and its precession will cause the pressure fluctuations which sometimes affect the stability of hydro power system considerably.

Draft genome sequence for virulent and avirulent strains of Xanthomonas arboricola isolated from Prunus spp. in Spain.

PubMed

Garita-Cambronero, Jerson; Palacio-Bielsa, Ana; López, María M; Cubero, Jaime

2016-01-01

Xanthomonas arboricola is a species in genus Xanthomonas which is mainly comprised of plant pathogens. Among the members of this taxon, X. arboricola pv. pruni, the causal agent of bacterial spot disease of stone fruits and almond, is distributed worldwide although it is considered a quarantine pathogen in the European Union. Herein, we report the draft genome sequence, the classification, the annotation and the sequence analyses of a virulent strain, IVIA 2626.1, and an avirulent strain, CITA 44, of X. arboricola associated with Prunus spp. The draft genome sequence of IVIA 2626.1 consists of 5,027,671 bp, 4,720 protein coding genes and 50 RNA encoding genes. The draft genome sequence of strain CITA 44 consists of 4,760,482 bp, 4,250 protein coding genes and 56 RNA coding genes. Initial comparative analyses reveals differences in the presence of structural and regulatory components of the type IV pilus, the type III secretion system, the type III effectors as well as variations in the number of the type IV secretion systems. The genome sequence data for these strains will facilitate the development of molecular diagnostics protocols that differentiate virulent and avirulent strains. In addition, comparative genome analysis will provide insights into the plant-pathogen interaction during the bacterial spot disease process.

Regulatory Considerations in the Design and Manufacturing of Implantable 3D‐Printed Medical Devices

PubMed Central

Morrison, Robert J.; Kashlan, Khaled N.; Flanangan, Colleen L.; Wright, Jeanne K.; Green, Glenn E.; Hollister, Scott J.

2015-01-01

Abstract Three‐dimensional (3D) printing, or additive manufacturing, technology has rapidly penetrated the medical device industry over the past several years, and innovative groups have harnessed it to create devices with unique composition, structure, and customizability. These distinctive capabilities afforded by 3D printing have introduced new regulatory challenges. The customizability of 3D‐printed devices introduces new complexities when drafting a design control model for FDA consideration of market approval. The customizability and unique build processes of 3D‐printed medical devices pose unique challenges in meeting regulatory standards related to the manufacturing quality assurance. Consistent material powder properties and optimal printing parameters such as build orientation and laser power must be addressed and communicated to the FDA to ensure a quality build. Postprinting considerations unique to 3D‐printed devices, such as cleaning, finishing and sterilization are also discussed. In this manuscript we illustrate how such regulatory hurdles can be navigated by discussing our experience with our group's 3D‐printed bioresorbable implantable device. PMID:26243449

78 FR 37850 - Quality Assurance Program Requirements (Operations)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-24

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0021] Quality Assurance Program Requirements (Operations... Regulatory Commission (NRC) is issuing a revision to Regulatory Guide (RG) 1.33, ``Quality Assurance Program... managerial and administrative Quality Assurance (QA) controls for nuclear power plants during operations...

Glacial and Intertidal Ecology: A Study Guide for the Third Grade. Alaska Sea Week Curriculum Series. Draft.

ERIC Educational Resources Information Center

Hopson, Dan; And Others

Two marine science units comprise this manual for teachers of elementary school students. Unit 1, "Shore Communities," involves mapping exercises and other investigations of the ecology of the intertidal zone. Unit 2, "The Glacier," focuses on glacial geology and the relationship of glaciers to the marine environment. Each unit…

Use of MCAT Data in Admissions. A Guide for Medical School Admissions Officers and Faculty.

ERIC Educational Resources Information Center

Mitchell, Karen J.

A description of the standardized, multiple-choice Medical College Admission Test (MCAT) and how to use it is offered. Medical school admissions officers medical educators, college faculty members, and practicing physicians are active participants in selecting content, drafting test specifications, and authoring questions for the exam. The MCAT is…

How To Proofread and Edit Your Writing: A Guide for Student Writers.

ERIC Educational Resources Information Center

Morgan, M.C.

Proofreading can be tedious and boring, especially if it is approached as correcting errors. But proofreading is not correcting errors so much as reviewing the paper for ideas and for readability. Sometimes classmates can help a student proofread--they can help assess the draft, propose some alternative solutions, and make some choices. This paper…

DDN New User Guide. Revision.

DTIC Science & Technology

1992-10-01

5 2.1 Network Overview ................................................ 5 2.2 Network Access Methods...to TAC and ?4ini-TAC users, such as common error messages, TAC commands, and instructions for performing file tranders. Section 5 , Network Use...originally known as Interface Message Processors, or IMPs. 5 THE DEFENSE DATA NETWORK DRAFt NIC 60001, October 1992 message do not necessarily take the same

Revision Strategies for Adolescent Writers: Moving Students in the Write Direction

ERIC Educational Resources Information Center

Borgese, Jolene; Heyler, Dick; Romano, Stephanie

2011-01-01

For many secondary students, writing effectively is the most elusive of the critical literacy skills needed for college and career readiness. And for many teachers, revision is the most difficult part of the writing process to tackle. How can adolescent writers be guided to revisit their work, to identify the weaknesses in their writing drafts,…

77 FR 16058 - Willapa National Wildlife Refuge, Pacific County, WA; Record of Decision for Final Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-19

... National Wildlife Refuge System, consistent with sound principles of fish and wildlife management... implementation. Alternative 2 is the foundation of our CCP. The CCP will guide our management and administration... management issues in our Draft and Final CCP/EIS. To address these issues, we developed and evaluated three...

Grade 4: Maryland--Geography. Maryland--History of the Colonial Period.

ERIC Educational Resources Information Center

Allegany County Board of Education, Cumberland, MD.

The curriculum guide presents a working draft of the fourth grade component of a K-6 social studies program using the expanding environments approach which was developed by the Allegany County Board of Education in Maryland. The overall objective is to help teachers assist their students in gaining the understanding needed to deal with the…

The Hawaiian Monarchy: Instructional Materials/Resources for Grade 7 Social Studies. Draft.

ERIC Educational Resources Information Center

Hawaii State Dept. of Education, Honolulu. Office of Instructional Services.

Materials in this curriculum guide for a seventh grade social studies course focus on the development of the monarchy period in Hawaii's history. Following a course outline, 10 study units cover map skills, early historical background, and the reigns of the following kings and queens: Kamehameha, Liholiho, Kauikeaouli, Alexander Liholiho, Lot,…

Every Body Needs First Aid... A Manual for LEP Students [Draft] and Teacher Guide.

ERIC Educational Resources Information Center

Adachi, Patricia

The manual contains both student and teacher materials for instruction in basic physiology and first aid. The instructional materials were developed for use with limited-English-proficient high school students, but are suitable for high school first aid classes because of their simplified English and format, sequential organization, detailed table…

78 FR 13081 - Draft Environmental Impact Statement for General Management Plan, Everglades National Park, Florida

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-26

... the General Management Plan (GMP) and East Everglades Wilderness Study (EEWS) for Everglades National Park (park). After it is finalized, the GMP/EEWS will guide the management of the park over the next 20... visitor use in the Park. The GMP will provide updated management direction for the entire park. The EEWS...

Professional Development Framework for e-Learning: A Guide for Advisers and Practitioners

ERIC Educational Resources Information Center

Smith, Ros

2007-01-01

In January 2006 the Learning and Skills Development Agency (LSDA) launched its draft publication, "A Professional Development Framework for e-Learning" (ePD) for consultation with the post-16 education and training sector. In March 2006 the Learning and Skills Council funded the Learning and Skills Network (LSN) to run a pilot to…

Environmental Quality Technology Demonstration, Evaluation and Transfer Activities

DTIC Science & Technology

1996-12-02

and Appropriate Requirements) and ARAR support documentation for interim and final Installation Restoration Program (IRP) remedial actions . During the...Relevant and Appropriate Requirements (ARARs) for Fort Devens , Massachusetts. Delivered Federal Environmental Legislative Power Curve in hard copy and... Remedial Actions . Delivered revised tables for Desk Guide on Interpretation of Applicable or Relevant and Appropriate Requirements — Interim Draft

Guiding the Noticing: Using a Dramatic Performance Experience to Promote Tellability in Narrative Writing

ERIC Educational Resources Information Center

Clark, Shanetia

2012-01-01

In this article, the author describes her use of dramatic performance to promote tellability in narrative writing within a seventh and eighth grade English and language arts classroom. By experiencing dramatic performance, the students were able to actively and physically perform the writing process: brainstorming, drafting, revising, and editing.…