Sample records for draft specifications requirements

  1. 46 CFR 174.040 - Stability requirements: general.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PERTAINING TO SPECIFIC VESSEL TYPES Special Rules Pertaining to Mobile Offshore Drilling Units § 174.040... draft for navigation, towing, or drilling afloat, or at a temporary draft when changing drafts. ...

  2. 46 CFR 174.040 - Stability requirements: general.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PERTAINING TO SPECIFIC VESSEL TYPES Special Rules Pertaining to Mobile Offshore Drilling Units § 174.040... draft for navigation, towing, or drilling afloat, or at a temporary draft when changing drafts. ...

  3. 77 FR 52692 - NIST Federal Information Processing Standard (FIPS) 140-3 (Second Draft), Security Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ...-03] NIST Federal Information Processing Standard (FIPS) 140-3 (Second Draft), Security Requirements... Technology (NIST), Commerce. ACTION: Notice and Request for Comments. SUMMARY: The National Institute of Standards and Technology (NIST) seeks additional comments on specific sections of Federal Information...

  4. 77 FR 39710 - Draft Guidance for Industry on Organ-Specific Warnings: Internal Analgesic, Antipyretic, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ...] Draft Guidance for Industry on Organ-Specific Warnings: Internal Analgesic, Antipyretic, and... Warnings: Internal Analgesic, Antipyretic, and Antirheumatic Drug Products for Over-the-Counter Human Use... enforcement discretion with regard to the liver warning required in the labeling. DATES: Although you can...

  5. The Research Proposal in Biomechanical and Biological Engineering Courses

    ERIC Educational Resources Information Center

    Harrison, Roger G.; Nollert, Matthias U.; Schmidtke, David W.; Sikavitsas, Vassilios I.

    2006-01-01

    Students in four biochemical and biological engineering courses for upper-­level undergraduates and graduate students were required to write a research proposal. Breaking the requirements down into segments (such as a summary with specific aims, rough draft, and final draft) due on different dates helped make the assignment more manageable for the…

  6. Mars Sample Handling Protocol Workshop Series: Workshop 4

    NASA Technical Reports Server (NTRS)

    Race Margaret S. (Editor); DeVincenzi, Donald L. (Editor); Rummel, John D. (Editor); Acevedo, Sara E. (Editor)

    2001-01-01

    In preparation for missions to Mars that will involve the return of samples to Earth, it will be necessary to prepare for the receiving, handling, testing, distributing, and archiving of martian materials here on Earth. Previous groups and committees have studied selected aspects of sample return activities, but specific detailed protocols for the handling and testing of returned samples must still be developed. To further refine the requirements for sample hazard testing and to develop the criteria for subsequent release of sample materials from quarantine, the NASA Planetary Protection Officer convened a series of workshops in 2000-2001. The overall objective of the Workshop Series was to produce a Draft Protocol by which returned martian sample materials can be assessed for biological hazards and examined for evidence of life (extant or extinct) while safeguarding the purity of the samples from possible terrestrial contamination. This report also provides a record of the proceedings of Workshop 4, the final Workshop of the Series, which was held in Arlington, Virginia, June 5-7, 2001. During Workshop 4, the sub-groups were provided with a draft of the protocol compiled in May 2001 from the work done at prior Workshops in the Series. Then eight sub-groups were formed to discuss the following assigned topics: Review and Assess the Draft Protocol for Physical/Chemical Testing Review and Assess the Draft Protocol for Life Detection Testing Review and Assess the Draft Protocol for Biohazard Testing Environmental and Health/Monitoring and Safety Issues Requirements of the Draft Protocol for Facilities and Equipment Contingency Planning for Different Outcomes of the Draft Protocol Personnel Management Considerations in Implementation of the Draft Protocol Draft Protocol Implementation Process and Update Concepts This report provides the first complete presentation of the Draft Protocol for Mars Sample Handling to meet planetary protection needs. This Draft Protocol, which was compiled from deliberations and recommendations from earlier Workshops in the Series, represents a consensus that emerged from the discussions of all the sub-groups assembled over the course of the five Workshops of the Series. These discussions converged on a conceptual approach to sample handling, as well as on specific analytical requirements. Discussions also identified important issues requiring attention, as well as research and development needed for protocol implementation.

  7. Draft standard for color AMLCDs in U.S. military aircraft

    NASA Astrophysics Data System (ADS)

    Hopper, Darrel G.; Dolezal, William K.; Schur, Keith; Liccione, John W.

    1994-06-01

    Flight instruments have begun to use color active liquid crystal displays (AMLCDs), signaling the beginning of a significant transition from electromechanical and cathode ray tube display designs to AMLCD designs. We have the opportunity with this new technology to establish common products capable of meeting user requirements for sunlight-readable, color and gray scale-capable, high-pixel-count, flat-panel displays for weapon systems. The Wright Laboratory is leading the development of standard and specification documentation for this new generation of display modules based on requirements for U.S. military aircraft. These requirements are similar in many ways to those of both the civil aviation and automotive industries. Accordingly, commonality with these applications is incorporated, where possible, along with the requirements for all military combat applications. Industry and government organizations are involved in this process through workshops and draft review processes. Military procurement specifications for combat system applications may use this information as a source of recommended best practice for this new generation of digital flat panel displays. The draft standard will be revised based upon continuing feedback by early 1995.

  8. 77 FR 20026 - Draft Guidance for Industry: Modified Risk Tobacco Product Applications; Availability; Agency...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-03

    ... appropriate scientific and medical experts, on the design and conduct of studies required for the assessment... functions, including the design and conduct of research, the oversight of specific studies, and the... any time (see 21 CFR 10.115(g)(5)), to ensure that the Agency considers your comment on this draft...

  9. 76 FR 2924 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; Adequacy of Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ... positions. No specific action or written response is required. DATES: Comment period expires 30 days after... new requirements or staff positions. No specific action or written response is required. Background... on the operation of Class 1E loads. These degraded voltage conditions will not be detected by the...

  10. Rotor systems research aircraft predesign study. Volume 4: Preliminary draft detail specification

    NASA Technical Reports Server (NTRS)

    Miller, A. N.; Linden, A. W.

    1972-01-01

    The RSRA requirements are presented in a detail specification format. Coverage of the requirements includes the following headings: (1) aircraft characteristics, (2) general features of design and construction, (3) aerodynamics, (4) structural design criteria, (5) flight control system, (6) propulsion subsystem, and (7) secondary power and distribution subsystem.

  11. Draft Plan to Develop Non-Intrusive Load Monitoring Test Protocols

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mayhorn, Ebony T.; Sullivan, Greg P.; Petersen, Joseph M.

    2015-09-29

    This document presents a Draft Plan proposed to develop a common test protocol that can be used to evaluate the performance requirements of Non-Intrusive Load Monitoring. Development on the test protocol will be focused on providing a consistent method that can be used to quantify and compare the performance characteristics of NILM products. Elements of the protocols include specifications for appliances to be used, metrics, instrumentation, and a procedure to simulate appliance behavior during tests. In addition, three priority use cases for NILM will be identified and their performance requirements will specified.

  12. Revision strategies of deaf student writers.

    PubMed

    Livingston, S

    1989-03-01

    Deaf high school students at different schools shared second drafts of their own narratives via an electronic bulletin board after conferencing with their repective teachers. This article characterizes the kinds of questions teachers asked during the conferences and the kinds of revisions the students made between first and second drafts. Results indicate that teachers most often ask questions that require student to provide more information; yet these questions do not affect revision as much as questions which require students to rephrase specific language. Students typically either added or substituted words or phrases that showed both similarities to and differences from the revision patterns of inexperienced writers with normal hearing. In the majority of cases, trained readers rated the deaf students' revised drafts better than their first attempts, signifying the central role revision plays in the composition process.

  13. Phase 111A Crew Interface Specifications Development for Inflight Maintenance and Stowage Functions

    NASA Technical Reports Server (NTRS)

    Carl, John G.

    1973-01-01

    This report presents the findings and data products developed during the Phase IIIA Crew Interface Specification Study for Inflight Maintenance and Stowage Functions, performed by General Electric for the NASA, Johnson Space Center with a set of documentation that can be used as definitive guidelines to improve the present process of defining, controlling and managing flight crew interface requirements that are related to inflight maintenance (including assembly and servicing) and stowage functions. During the Phase IIIA contract period, the following data products were developed: 1) Projected NASA Crew Procedures/Flight Data File Development Process. 2) Inflight Maintenance Management Process Description. 3) Preliminary Draft, General Specification, Inflight Maintenance Management Requirements. 4) Inflight Maintenance Operational Process Description. 5) Preliminary Draft, General Specification, Inflight Maintenance Task and Support Requirements Analysis. 6) Suggested IFM Data Processing Reports for Logistics Management The above Inflight Maintenance data products have been developed during the Phase IIIA study after review of Space Shuttle Program Documentation, including the Level II Integrated Logistics Requirements and other DOD and NASA data relative to Payloads Accommodations and Satellite On-Orbit Servicing. These Inflight Maintenance data products were developed to be in consonance with Space Shuttle Program technical and management requirements.

  14. Mission-oriented requirements for updating MIL-H-8501: Calspan proposed structure and rationale

    NASA Technical Reports Server (NTRS)

    Chalk, C. R.; Radford, R. C.

    1985-01-01

    This report documents the effort by Arvin/Calspan Corporation to formulate a revision of MIL-H-8501A in terms of Mission-Oriented Flying Qualities Requirements for Military Rotorcraft. Emphasis is placed on development of a specification structure which will permit addressing Operational Missions and Flight Phases, Flight Regions, Classification of Required Operational Capability, Categorization of Flight Phases, and Levels of Flying Qualities. A number of definitions is established to permit addressing the rotorcraft state, flight envelopes, environments, and the conditions under which degraded flying qualities are permitted. Tentative requirements are drafted for Required Operational Capability Class 1. Also included is a Background Information and Users Guide for the draft specification structure proposed for the MIL-H-8501A revision. The report also contains a discussion of critical data gaps and attempts to prioritize these data gaps and to suggest experiments that should be performed to generate data needed to support formulation of quantitative design criteria for the additional Operational Capability Classes 2, 3, and 4.

  15. 18 CFR 5.24 - Applications not requiring a draft NEPA document.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... requiring a draft NEPA document. 5.24 Section 5.24 Conservation of Power and Water Resources FEDERAL ENERGY... APPLICATION PROCESS § 5.24 Applications not requiring a draft NEPA document. (a) If the Commission determines... environmental impact statement and that a draft environmental assessment will not be required, the Commission...

  16. 18 CFR 5.24 - Applications not requiring a draft NEPA document.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... requiring a draft NEPA document. 5.24 Section 5.24 Conservation of Power and Water Resources FEDERAL ENERGY... APPLICATION PROCESS § 5.24 Applications not requiring a draft NEPA document. (a) If the Commission determines... environmental impact statement and that a draft environmental assessment will not be required, the Commission...

  17. 18 CFR 5.24 - Applications not requiring a draft NEPA document.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... requiring a draft NEPA document. 5.24 Section 5.24 Conservation of Power and Water Resources FEDERAL ENERGY... APPLICATION PROCESS § 5.24 Applications not requiring a draft NEPA document. (a) If the Commission determines... environmental impact statement and that a draft environmental assessment will not be required, the Commission...

  18. 76 FR 10908 - Draft Guidance for Industry on Medication Guides-Distribution Requirements and Inclusion of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ...] Draft Guidance for Industry on Medication Guides--Distribution Requirements and Inclusion of Medication... a draft guidance for industry entitled ``Medication Guides--Distribution Requirements and Inclusion... Inclusion of Medication Guides in Risk Evaluation and Mitigation Strategies (REMS).'' This draft guidance is...

  19. Department of the Treasury, Internal Revenue Service: Statement in Preamble to Regulations That Cash Balance Plans Are Not Age-Discriminatory

    DTIC Science & Technology

    2001-03-21

    has any record of a draft of the regulation or the preamble being sent to the EEOC . EEOC officials had no recollection of receiving a draft of either...document. To the best of their recollection, IRS officials believe that EEOC was not made aware of the regulation or preamble. As indicated, DOL was...it issued the final regulation . Specifically, EEOC argues that ORBA ‘86 required Treasury to coordinate with EEOC before issuing regulations or

  20. 18 CFR 5.25 - Applications requiring a draft NEPA document.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY... APPLICATION PROCESS § 5.25 Applications requiring a draft NEPA document. (a) If the Commission determines that a license application will be processed with an environmental impact statement, or a draft and final...

  1. 18 CFR 5.25 - Applications requiring a draft NEPA document.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY... APPLICATION PROCESS § 5.25 Applications requiring a draft NEPA document. (a) If the Commission determines that a license application will be processed with an environmental impact statement, or a draft and final...

  2. 18 CFR 5.25 - Applications requiring a draft NEPA document.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY... APPLICATION PROCESS § 5.25 Applications requiring a draft NEPA document. (a) If the Commission determines that a license application will be processed with an environmental impact statement, or a draft and final...

  3. Mississippi Curriculum Framework for General Drafting (Program CIP: 48.0101--Drafting, General). Secondary Programs.

    ERIC Educational Resources Information Center

    Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.

    This document, which reflects Mississippi's statutory requirement that instructional programs be based on core curricula and performance-based assessment, contains outlines of the instructional units required in local instructional management plans and daily lesson plans for two secondary-level courses in drafting: drafting I and II. Presented…

  4. 77 FR 56851 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... Bioequivalence Recommendations; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... draft product-specific bioequivalence (BE) recommendations. The recommendations provide product-specific guidance on the design of BE studies to support abbreviated new drug applications (ANDAs). In the Federal...

  5. 75 FR 60129 - Draft Guidance for Industry and Investigators on Safety Reporting Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... with the new requirements in the final rule entitled ``Investigational New Drug Safety Reporting...] Draft Guidance for Industry and Investigators on Safety Reporting Requirements for Investigational New... the agency considers your comment on this draft guidance before it begins work on the final version of...

  6. 78 FR 66940 - Regulatory Requirements for Hearing Aid Devices and Personal Sound Amplification Products; Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-D-1295] Regulatory Requirements for Hearing Aid Devices and Personal Sound Amplification Products; Draft Guidance for... draft guidance entitled ``Regulatory Requirements for Hearing Aid Devices and Personal Sound...

  7. 75 FR 45677 - Draft Regulatory Guide, DG-1216,”Plant-Specific Applicability of Transition Break Size Specified...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0229] Draft Regulatory Guide, DG-1216,''Plant-Specific... Commission (NRC) is extending the public comment period for DG-1216 from August 25, 2010 to November 8, 2010... [email protected] . The Draft Regulatory Guide, DG-1216, ``Plant- Specific Applicability of...

  8. 48 CFR 22.1003-5 - Some examples of contracts covered.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CFR 4.130 for additional examples): (a) Motor pool operation, parking, taxicab, and ambulance services...) Certain specialized services requiring specific skills, such as drafting, illustrating, graphic arts..., engines, electrical motors, vehicles, and electronic, office and related business and construction...

  9. 46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  10. 46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  11. 46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  12. 46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  13. 46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  14. High Speed Digital Camera Technology Review

    NASA Technical Reports Server (NTRS)

    Clements, Sandra D.

    2009-01-01

    A High Speed Digital Camera Technology Review (HSD Review) is being conducted to evaluate the state-of-the-shelf in this rapidly progressing industry. Five HSD cameras supplied by four camera manufacturers participated in a Field Test during the Space Shuttle Discovery STS-128 launch. Each camera was also subjected to Bench Tests in the ASRC Imaging Development Laboratory. Evaluation of the data from the Field and Bench Tests is underway. Representatives from the imaging communities at NASA / KSC and the Optical Systems Group are participating as reviewers. A High Speed Digital Video Camera Draft Specification was updated to address Shuttle engineering imagery requirements based on findings from this HSD Review. This draft specification will serve as the template for a High Speed Digital Video Camera Specification to be developed for the wider OSG imaging community under OSG Task OS-33.

  15. A student guide to proofreading and writing in science.

    PubMed

    Hyatt, Jon-Philippe K; Bienenstock, Elisa Jayne; Tilan, Jason U

    2017-09-01

    Scientific writing requires a distinct style and tone, whether the writing is intended for an undergraduate assignment or publication in a peer-reviewed journal. From the first to the final draft, scientific writing is an iterative process requiring practice, substantial feedback from peers and instructors, and comprehensive proofreading on the part of the writer. Teaching writing or proofreading is not common in university settings. Here, we present a collection of common undergraduate student writing mistakes and put forth suggestions for corrections as a first step toward proofreading and enhancing readability in subsequent draft versions. Additionally, we propose specific strategies pertaining to word choice, structure, and approach to make products more fluid and focused for an appropriate target audience. Copyright © 2017 the American Physiological Society.

  16. 32 CFR 651.49 - Preliminary phase.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... data, including required studies. (3) Preparation of draft and final EISs (DEISs and FEISs), and... relationship between the timing of the preparation of environmental analyses and the tentative planning and..., preparation of a general expected schedule for future specific implementing (tiered) actions that will involve...

  17. 32 CFR 651.49 - Preliminary phase.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... data, including required studies. (3) Preparation of draft and final EISs (DEISs and FEISs), and... relationship between the timing of the preparation of environmental analyses and the tentative planning and..., preparation of a general expected schedule for future specific implementing (tiered) actions that will involve...

  18. 46 CFR 174.040 - Stability requirements: general.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... metacentric height in the upright equilibrium position for the full range of drafts, whether at the operating draft for navigation, towing, or drilling afloat, or at a temporary draft when changing drafts. ...

  19. 46 CFR 174.040 - Stability requirements: general.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... metacentric height in the upright equilibrium position for the full range of drafts, whether at the operating draft for navigation, towing, or drilling afloat, or at a temporary draft when changing drafts. ...

  20. Draft Geologic Disposal Requirements Basis for STAD Specification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ilgen, Anastasia G.; Bryan, Charles R.; Hardin, Ernest

    2015-03-25

    This document provides the basis for requirements in the current version of Performance Specification for Standardized Transportation, Aging, and Disposal Canister Systems, (FCRD-NFST-2014-0000579) that are driven by storage and geologic disposal considerations. Performance requirements for the Standardized Transportation, Aging, and Disposal (STAD) canister are given in Section 3.1 of that report. Here, the requirements are reviewed and the rationale for each provided. Note that, while FCRD-NFST-2014-0000579 provides performance specifications for other components of the STAD storage system (e.g. storage overpack, transfer and transportation casks, and others), these have no impact on the canister performance during disposal, and are not discussedmore » here.« less

  1. Guideline series: Control of volatile organic compound emissions from wood furniture manufacturing operations. Draft report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-08-01

    This draft Control Techniques Guidelines (CTG) provides necessary guidance for development of regulations to limit emissions of volatile organic compounds (VOC`s) from wood furniture finishing and cleaning operations. This guidance includes emission limits for specific wood furniture finishing steps and work pratices to reduce waste and evaporation through pollution prevention methods; these represent reasonably available control technology for wood furniture finishing and cleaning operations. This document is intended to provide State and local air pollution authorities with an information base for proceeding with their own analyses of RACT to meet statutory requirements.

  2. Evaluating Urban Resilience to Climate Change: A Multi-Sector Approach (External Review Draft)

    EPA Science Inventory

    Climate change impacts are diverse, long-term, and not easily predictable. Adapting to climate change requires making context specific and forward-looking decisions regarding a variety of climate change impacts and vulnerabilities when the future is highly uncertain. EPA scientis...

  3. 49 CFR 229.61 - Draft system.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Draft system. 229.61 Section 229.61 Transportation... TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Draft System § 229.61 Draft system. (a) A... absorbed by friction devices or draft gears that exceeds one-half inches. (5) A broken or cracked coupler...

  4. 49 CFR 229.61 - Draft system.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Draft system. 229.61 Section 229.61 Transportation... TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Draft System § 229.61 Draft system. (a) A... absorbed by friction devices or draft gears that exceeds one-half inches. (5) A broken or cracked coupler...

  5. 49 CFR 229.61 - Draft system.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Draft system. 229.61 Section 229.61 Transportation... TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Draft System § 229.61 Draft system. (a) A... absorbed by friction devices or draft gears that exceeds one-half inches. (5) A broken or cracked coupler...

  6. 18 CFR 5.24 - Applications not requiring a draft NEPA document.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... requiring a draft NEPA document. 5.24 Section 5.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... assessment issued pursuant to this paragraph must include draft license articles, a preliminary determination...

  7. 18 CFR 5.24 - Applications not requiring a draft NEPA document.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requiring a draft NEPA document. 5.24 Section 5.24 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... assessment issued pursuant to this paragraph must include draft license articles, a preliminary determination...

  8. 46 CFR 151.03-35 - Limiting draft.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Limiting draft. 151.03-35 Section 151.03-35 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Definitions § 151.03-35 Limiting draft. Maximum allowable draft to which a barge may be loaded. Limiting draft is a function of hull type and cargo specific gravity...

  9. 46 CFR 151.03-35 - Limiting draft.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Limiting draft. 151.03-35 Section 151.03-35 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Definitions § 151.03-35 Limiting draft. Maximum allowable draft to which a barge may be loaded. Limiting draft is a function of hull type and cargo specific gravity...

  10. 46 CFR 151.03-35 - Limiting draft.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Limiting draft. 151.03-35 Section 151.03-35 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Definitions § 151.03-35 Limiting draft. Maximum allowable draft to which a barge may be loaded. Limiting draft is a function of hull type and cargo specific gravity...

  11. 46 CFR 151.03-35 - Limiting draft.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Limiting draft. 151.03-35 Section 151.03-35 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Definitions § 151.03-35 Limiting draft. Maximum allowable draft to which a barge may be loaded. Limiting draft is a function of hull type and cargo specific gravity...

  12. 46 CFR 151.03-35 - Limiting draft.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Limiting draft. 151.03-35 Section 151.03-35 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Definitions § 151.03-35 Limiting draft. Maximum allowable draft to which a barge may be loaded. Limiting draft is a function of hull type and cargo specific gravity...

  13. 46 CFR 167.55-1 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Section 167.55-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Special Markings Required § 167.55-1 Draft marks and draft indicating systems. (a... are of uniform height equal to the vertical spacing between consecutive marks. (f) Draft marks must be...

  14. 46 CFR 167.55-1 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Section 167.55-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Special Markings Required § 167.55-1 Draft marks and draft indicating systems. (a... are of uniform height equal to the vertical spacing between consecutive marks. (f) Draft marks must be...

  15. 46 CFR 167.55-1 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Section 167.55-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Special Markings Required § 167.55-1 Draft marks and draft indicating systems. (a... are of uniform height equal to the vertical spacing between consecutive marks. (f) Draft marks must be...

  16. 46 CFR 167.55-1 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Section 167.55-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Special Markings Required § 167.55-1 Draft marks and draft indicating systems. (a... are of uniform height equal to the vertical spacing between consecutive marks. (f) Draft marks must be...

  17. 46 CFR 167.55-1 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 167.55-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Special Markings Required § 167.55-1 Draft marks and draft indicating systems. (a... are of uniform height equal to the vertical spacing between consecutive marks. (f) Draft marks must be...

  18. 77 FR 33489 - Draft Offender Tracking System Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... Tracking System Standard AGENCY: National Institute of Justice. ACTION: Notice of Draft Offender Tracking System Standard, Selection and Application Guide, and Certification Program Requirements. SUMMARY: In an...) A draft standard entitled, ``Offender Tracking System Standard'' (2) a draft companion document...

  19. 75 FR 54347 - Draft Guidance for Industry: Bar Code Label Requirements-Questions and Answers (Question 12...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    ...] Draft Guidance for Industry: Bar Code Label Requirements-- Questions and Answers (Question 12 Update... Administration (FDA) is announcing the availability of a draft document entitled ``Guidance for Industry: Bar... guidance provides you, manufacturers of a licensed vaccine, with advice concerning compliance with the bar...

  20. 12 CFR 516.20 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true What information must I include in my draft... What information must I include in my draft business plan? If you must submit a draft business plan... described in the savings association's draft business plan; and (d) Demonstrate how applicable requirements...

  1. 12 CFR 516.20 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 6 2012-01-01 2012-01-01 false What information must I include in my draft... What information must I include in my draft business plan? If you must submit a draft business plan... described in the savings association's draft business plan; and (d) Demonstrate how applicable requirements...

  2. 12 CFR 116.20 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false What information must I include in my draft... What information must I include in my draft business plan? If you must submit a draft business plan... described in the savings association's draft business plan; and (d) Demonstrate how applicable requirements...

  3. 12 CFR 116.20 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false What information must I include in my draft... What information must I include in my draft business plan? If you must submit a draft business plan... described in the savings association's draft business plan; and (d) Demonstrate how applicable requirements...

  4. 12 CFR 116.20 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false What information must I include in my draft... What information must I include in my draft business plan? If you must submit a draft business plan... described in the savings association's draft business plan; and (d) Demonstrate how applicable requirements...

  5. 12 CFR 516.20 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true What information must I include in my draft... What information must I include in my draft business plan? If you must submit a draft business plan... described in the savings association's draft business plan; and (d) Demonstrate how applicable requirements...

  6. 12 CFR 516.20 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false What information must I include in my draft... What information must I include in my draft business plan? If you must submit a draft business plan... described in the savings association's draft business plan; and (d) Demonstrate how applicable requirements...

  7. 76 FR 13436 - NIJ Request for Comments on Draft Vehicular Digital Multimedia Evidence Recording System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ... Comments on Draft Vehicular Digital Multimedia Evidence Recording System Certification Program Requirements for Law Enforcement and Draft Law Enforcement Vehicular Digital Multimedia Evidence Recording System... two draft documents: ``Vehicular Digital Multimedia Evidence Recording System Certification Program...

  8. A Project Provides an Opportunity: Multiple Drafts of an Introduction Require Students to Engage Deeply with the Literature

    ERIC Educational Resources Information Center

    Slade, David J.; Miller, Justin S.

    2017-01-01

    A 10 week project in the organic chemistry laboratory provided the opportunity to require students to write four drafts of an introduction. Student understanding of what a good introduction entails was transformed by their fourth draft, as evidenced by higher citation counts and the inclusion of more and better figures, which reveals greater…

  9. 14 CFR 1216.312 - Timing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... EPA notice of a NASA draft EIS. (2) Thirty days after publication of an EPA notice of a NASA final EIS. (b) When necessary to comply with other specific statutory requirements, NASA shall consult with and... the proposed action (the major decision point of § 1216.304(b)) shall be made by NASA until the later...

  10. 14 CFR 1216.312 - Timing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... EPA notice of a NASA draft EIS. (2) Thirty days after publication of an EPA notice of a NASA final EIS. (b) When necessary to comply with other specific statutory requirements, NASA shall consult with and... the proposed action (the major decision point of § 1216.304(b)) shall be made by NASA until the later...

  11. 14 CFR 1216.312 - Timing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... EPA notice of a NASA draft EIS. (2) Thirty days after publication of an EPA notice of a NASA final EIS. (b) When necessary to comply with other specific statutory requirements, NASA shall consult with and... the proposed action (the major decision point of § 1216.304(b)) shall be made by NASA until the later...

  12. Orientation, Sketching, Mechanical Drawing, Drafting--Basic: 9253.01.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    The course introduces the student to the drafting trade, freehand sketching, and basic mechanical drawing. The course has no prerequisites and will guide the student into drafting concepts and serve as a foundation for further study in vocational drafting. Requiring a total of 45 class hours, eight hours are utilized in orientation, 15 hours are…

  13. 46 CFR 167.65-40 - Draft.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Draft. 167.65-40 Section 167.65-40 Shipping COAST GUARD... Requirements § 167.65-40 Draft. The master of every nautical school ship over 50 gross tons shall, whenever leaving port, enter the maximum draft of his nautical school ship in the log book. ...

  14. 46 CFR 167.65-40 - Draft.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Draft. 167.65-40 Section 167.65-40 Shipping COAST GUARD... Requirements § 167.65-40 Draft. The master of every nautical school ship over 50 gross tons shall, whenever leaving port, enter the maximum draft of his nautical school ship in the log book. ...

  15. 46 CFR 167.65-40 - Draft.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Draft. 167.65-40 Section 167.65-40 Shipping COAST GUARD... Requirements § 167.65-40 Draft. The master of every nautical school ship over 50 gross tons shall, whenever leaving port, enter the maximum draft of his nautical school ship in the log book. ...

  16. 46 CFR 167.65-40 - Draft.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Draft. 167.65-40 Section 167.65-40 Shipping COAST GUARD... Requirements § 167.65-40 Draft. The master of every nautical school ship over 50 gross tons shall, whenever leaving port, enter the maximum draft of his nautical school ship in the log book. ...

  17. 46 CFR 167.65-40 - Draft.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Draft. 167.65-40 Section 167.65-40 Shipping COAST GUARD... Requirements § 167.65-40 Draft. The master of every nautical school ship over 50 gross tons shall, whenever leaving port, enter the maximum draft of his nautical school ship in the log book. ...

  18. Editing Tips for Technical Publications in the Joint Nuclear Weapons Publication System (JNWPS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    ALLEN, TARA S.

    2002-12-01

    These editing tips contain helpful suggestions to assist writers who are writing, editing, and publishing technical publications in the JNWPS. The suggestions clarify some of the most common writing problems and requirements of two publications used in the JNWPS: ''DOE-DTRA TP 1-1, Joint Nuclear Weapons Publications System Operating Procedures, Specifications, and Standards, and United States Government Printing Office Style Manual''. Topics include requirements for abbreviations, formats for drafts, layouts of illustrations and tables, appropriate wording for interim changes, guidance for creating a list of effective pages, how to insert and delete pages and paragraphs, referencing other technical publications, use ofmore » revision bars, requirements for safety precautions, use of hyphens, and how to place warnings, cautions, and notes. Also included are a writer's checklist, samples of draft title pages, and a section of helpful tips for the writers who use the department's desktop publishing software program, Adobe{reg_sign} FrameMaker{reg_sign}.« less

  19. One Methodology for Proving Compliance to the Commercial Crew Program (CCP) Abort Capability Requirement

    NASA Technical Reports Server (NTRS)

    Proud, Ryan; Adam, Jason

    2011-01-01

    As of Draft 4.0 of the CCT-REQ-1130 requirements document for CCP, ISS Crew Transportation and Services Requirements Document, specific language for the verification of the abort capability requirement, 3.3.1.4, was added. The abort capability requirement ensures that the CTS under dispersed conditions is always capable of aborting from a failed LV. The Integrated Aborts IPT was asked to author a memo for how this verification might be completed. The following memo dictates one way that this requirement and its verification could be met, but this is the not the only method.

  20. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  1. 40 CFR 270.135 - What must the Director include in a draft RAP?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... draft RAP? 270.135 Section 270.135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Action Plans (RAPs) Getting A Rap Approved § 270.135 What must the Director include in a draft RAP? If the Director prepares a draft RAP, it must include the: (a) Information required under § 270.110(a...

  2. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  3. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  4. 40 CFR 270.135 - What must the Director include in a draft RAP?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... draft RAP? 270.135 Section 270.135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Action Plans (RAPs) Getting A Rap Approved § 270.135 What must the Director include in a draft RAP? If the Director prepares a draft RAP, it must include the: (a) Information required under § 270.110(a...

  5. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  6. 40 CFR 270.135 - What must the Director include in a draft RAP?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... draft RAP? 270.135 Section 270.135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Action Plans (RAPs) Getting A Rap Approved § 270.135 What must the Director include in a draft RAP? If the Director prepares a draft RAP, it must include the: (a) Information required under § 270.110(a...

  7. 40 CFR 270.135 - What must the Director include in a draft RAP?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... draft RAP? 270.135 Section 270.135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Action Plans (RAPs) Getting A Rap Approved § 270.135 What must the Director include in a draft RAP? If the Director prepares a draft RAP, it must include the: (a) Information required under § 270.110(a...

  8. 40 CFR 270.135 - What must the Director include in a draft RAP?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... draft RAP? 270.135 Section 270.135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Action Plans (RAPs) Getting A Rap Approved § 270.135 What must the Director include in a draft RAP? If the Director prepares a draft RAP, it must include the: (a) Information required under § 270.110(a...

  9. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  10. 75 FR 42466 - Notice of Availability of Draft Environmental Impact Statement and Public Meeting for the AREVA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... electrical transmission line required to power the proposed EREF. On March 17, 2010, the NRC granted an... facility. Specifically, AES proposes to use gas centrifuge technology to enrich the uranium-235 isotope... centrifuge-based technology to enrich the uranium- 235 isotope found in natural uranium to concentrations up...

  11. The National Shipbuilding Research Program. Proceedings of the REAPS Technical Symposium held June 15-16, 1976 Atlanta, Georgia

    DTIC Science & Technology

    1976-06-01

    the imformation needed to perform the design funct ions, but will also provide the user with the details required to interact with other individuals...several calls of basic drafting (DRA) macros. The deck heights are constant andincluded in the coding. Al - identifies the specific frame to be retrived

  12. 78 FR 54899 - Draft Guidance for Industry on Specification of the Unique Facility Identifier System for Drug...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... 1995 (the PRA) (44 U.S.C. 3501-3520), Federal Agencies must obtain approval from the Office of... collection to OMB for approval. To comply with this requirement, FDA is publishing this notice of the... submission process functions most efficiently and effectively when the information is provided in a...

  13. 78 FR 20925 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-08

    ... Recommendations; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and...-specific bioequivalence (BE) recommendations. The recommendations provide product-specific guidance on the design of BE studies to support abbreviated new drug applications (ANDAs). In the Federal Register of...

  14. 77 FR 35688 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-14

    ... Recommendations; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and...-specific bioequivalence (BE) recommendations. The recommendations provide product-specific guidance on the design of BE studies to support abbreviated new drug applications (ANDAs). In the Federal Register of...

  15. 77 FR 16842 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... Recommendations; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and...-specific bioequivalence (BE) recommendations. The recommendations provide product-specific guidance on the design of BE studies to support abbreviated new drug applications (ANDAs). In the Federal Register of...

  16. Paperless Contract Folder’s (PCF) DoD 5015.2 Certification

    DTIC Science & Technology

    2010-06-01

    Draft Version Controls ...........................................................11 i. Electronic Routing of Purchase Request (Funding) Documents...of electronic records, version control , robust search and retrieval, and automated disposition that is compliant with legal requirements. As shown...h. Draft Version Controls Draft and versioning controls track the changes to the documents once they are saved. Draft numbers (0.1, 0.2, 0.3

  17. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false How do I make my draft materials... Preconstruction Requirements: Materials Separation Plan § 60.1070 How do I make my draft materials separation plan available to the public? (a) Distribute your draft materials separation plan to the main public libraries in...

  18. 12 CFR 390.104 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false What information must I include in my draft... Application Processing Procedures § 390.104 What information must I include in my draft business plan? If you are required to submit a draft business plan under § 309.103, your plan must: (a) Clearly and...

  19. 12 CFR 390.104 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false What information must I include in my draft... Application Processing Procedures § 390.104 What information must I include in my draft business plan? If you are required to submit a draft business plan under § 309.103, your plan must: (a) Clearly and...

  20. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false How do I make my draft materials... Preconstruction Requirements: Materials Separation Plan § 60.1070 How do I make my draft materials separation plan available to the public? (a) Distribute your draft materials separation plan to the main public libraries in...

  1. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false How do I make my draft materials... Preconstruction Requirements: Materials Separation Plan § 60.1070 How do I make my draft materials separation plan available to the public? (a) Distribute your draft materials separation plan to the main public libraries in...

  2. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false How do I make my draft materials... Preconstruction Requirements: Materials Separation Plan § 60.1070 How do I make my draft materials separation plan available to the public? (a) Distribute your draft materials separation plan to the main public libraries in...

  3. 12 CFR 390.104 - What information must I include in my draft business plan?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 5 2012-01-01 2012-01-01 false What information must I include in my draft... Application Processing Procedures § 390.104 What information must I include in my draft business plan? If you are required to submit a draft business plan under § 309.103, your plan must: (a) Clearly and...

  4. 75 FR 65293 - Draft Guidelines on Pharmacovigilance of Veterinary Medicinal Products: Electronic Standards for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ...] Draft Guidelines on Pharmacovigilance of Veterinary Medicinal Products: Electronic Standards for... Requirements for the Registration of Veterinary Medicinal Products (VICH) has developed a draft guideline titled ``Pharmacovigilance of Veterinary Medicinal Products: Electronic Standards for Transfer of Data...

  5. 78 FR 52777 - Draft Guidance for Industry on Bioequivalence Recommendations for Risperidone Injection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-26

    ...] (Formerly Docket No. 2007D-0168) Draft Guidance for Industry on Bioequivalence Recommendations for... industry entitled ``Draft Guidance on Risperidone.'' The guidance provides specific recommendations on the design of bioequivalence (BE) studies to support abbreviated new drug applications (ANDAs) for...

  6. 33 CFR 157.10a - Segregated ballast tanks, crude oil washing systems, and dedicated clean ballast tanks for...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... tanks with a total capacity to meet the draft and trim requirements in paragraph (d) of this section; or...) Segregated ballast tanks with a total capacity to meet the draft and trim requirements in paragraph (d) of... trim requirements in paragraph (d) of this section and that meet the design and equipment requirements...

  7. 33 CFR 157.10a - Segregated ballast tanks, crude oil washing systems, and dedicated clean ballast tanks for...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... tanks with a total capacity to meet the draft and trim requirements in paragraph (d) of this section; or...) Segregated ballast tanks with a total capacity to meet the draft and trim requirements in paragraph (d) of... trim requirements in paragraph (d) of this section and that meet the design and equipment requirements...

  8. 24 CFR 58.60 - Preparation and filing of environmental impact statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... ENVIRONMENTAL RESPONSIBILITIES Environmental Review Process: Procedures for Draft, Final and Supplemental... responsible entity must prepare the draft environmental impact statement (DEIS) and the final environmental... may request waivers from the time requirements specified for the draft and final EIS as prescribed in...

  9. 24 CFR 58.60 - Preparation and filing of environmental impact statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... ENVIRONMENTAL RESPONSIBILITIES Environmental Review Process: Procedures for Draft, Final and Supplemental... responsible entity must prepare the draft environmental impact statement (DEIS) and the final environmental... may request waivers from the time requirements specified for the draft and final EIS as prescribed in...

  10. 24 CFR 58.60 - Preparation and filing of environmental impact statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... ENVIRONMENTAL RESPONSIBILITIES Environmental Review Process: Procedures for Draft, Final and Supplemental... responsible entity must prepare the draft environmental impact statement (DEIS) and the final environmental... may request waivers from the time requirements specified for the draft and final EIS as prescribed in...

  11. 24 CFR 58.60 - Preparation and filing of environmental impact statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... ENVIRONMENTAL RESPONSIBILITIES Environmental Review Process: Procedures for Draft, Final and Supplemental... responsible entity must prepare the draft environmental impact statement (DEIS) and the final environmental... may request waivers from the time requirements specified for the draft and final EIS as prescribed in...

  12. 75 FR 38502 - Notice of Availability of Draft Environmental Impact Statement for the Sunridge Properties in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... require the filling of approximately 29.7 acres of waters of the United States, including wetlands. The... projects in the Sunridge Specific Plan area have been built. The Proposed Action is the construction of the... approximately 1.4 acres of waters of the U.S., including wetlands, to construct 134 houses, roadways, and other...

  13. 18 CFR 5.25 - Applications requiring a draft NEPA document.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... include for comment draft license articles, a preliminary determination of the consistency of each fish...

  14. 18 CFR 5.25 - Applications requiring a draft NEPA document.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... a draft NEPA document. 5.25 Section 5.25 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE... include for comment draft license articles, a preliminary determination of the consistency of each fish...

  15. 18 CFR 5.16 - Preliminary licensing proposal.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... proposal; and (3) Include the potential applicant's draft environmental analysis by resource area of the... draft license application which includes the contents of a license application required by § 5.18 instead of the Preliminary Licensing Proposal. A potential applicant that elects to file a draft license...

  16. 77 FR 7585 - Draft Guidance for Industry on Bioequivalence Recommendations for Rifaximin Tablets; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... (rifaximin-550). The recommendations provide specific guidance on the design of bioequivalence (BE) studies... studies to support ANDAs for rifaximin-200 (Draft Rifaximin-200 BE Recommendations). FDA is now issuing a...] Draft Guidance for Industry on Bioequivalence Recommendations for Rifaximin Tablets; Availability AGENCY...

  17. 78 FR 17943 - Draft Program-Specific Guidance About Fixed Gauge Licenses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-25

    ... is requesting public comment on draft NUREG-1556, Volume 4, Revision 1, ``Consolidated Guidance About... sensitive information, and changes in regulatory policies and practices. This document is intended for use...-415- 4737, or by email to [email protected] . The draft NUREG-1556, Volume 4, Revision 1, is...

  18. 48 CFR 1552.211-77 - Final reports.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... reports. As prescribed in 1511.011-77, insert this contract clause when a contract requires both a draft and a final report. FINAL REPORTS (SEP 2013) (a) “Draft Report”__The Contractor shall submit to the Contracting Officer's Representative __ copies of the draft final report on or before ___ (date) __ The...

  19. Centering Objects in the Workspace

    ERIC Educational Resources Information Center

    Free, Cory

    2005-01-01

    Drafters must be detail-oriented people. The objects they draw are interpreted and then built with the extreme precision required by today's manufacturers. Now that computer-aided drafting (CAD) has taken over the drafting profession, anything less than exact precision is unacceptable. In her drafting classes, the author expects her students to…

  20. Teaching Drafting 101: What Comes First?

    ERIC Educational Resources Information Center

    Carkhuff, Don

    2006-01-01

    Employers require pristine drawings that convey clarity and precision for the production of goods. Can a change in sequence of instruction be expeditious and help teachers better prepare their students for the workplace? Research suggests that combining traditional drafting and computer-aided drafting (CAD) instruction makes sense. It is analogous…

  1. 77 FR 39800 - Nondiscrimination on the Basis of Disability in Air Travel: Draft Technical Assistance Manual

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... specific learning disabilities. (Sec. 382.3). What is not considered a physical or mental impairment... Secretary 14 CFR Part 382 Nondiscrimination on the Basis of Disability in Air Travel: Draft Technical... [Docket No. DOT-OST-2012--0098] Nondiscrimination on the Basis of Disability in Air Travel: Draft...

  2. Whet Students' Appetites with Food-Related Drafting Project

    ERIC Educational Resources Information Center

    Pucillo, John M.

    2010-01-01

    Students sometimes find introductory drafting and design a boring subject. They must learn the basic skills necessary for drafting and architecture and this may require repetition in order to reinforce those skills. One way to keep students interested is to have them draw objects they encounter in their own lives instead of abstract machine parts…

  3. 10 CFR 51.75 - Draft environmental impact statement-construction permit, early site permit, or combined license.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... required. 5 The impact statement shall take account of dose commitments and health effects from fuel cycle... the site proposed. The draft environmental impact statement must not include an assessment of the... certification environmental assessment, then the draft combined license environmental impact statement shall...

  4. 10 CFR 51.75 - Draft environmental impact statement-construction permit, early site permit, or combined license.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... required. 5 The impact statement shall take account of dose commitments and health effects from fuel cycle... the site proposed. The draft environmental impact statement must not include an assessment of the... certification environmental assessment, then the draft combined license environmental impact statement shall...

  5. 10 CFR 51.75 - Draft environmental impact statement-construction permit, early site permit, or combined licesne.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... required. 5 The impact statement shall take account of dose commitments and health effects from fuel cycle... the site proposed. The draft environmental impact statement must not include an assessment of the... certification environmental assessment, then the draft combined license environmental impact statement shall...

  6. 10 CFR 51.75 - Draft environmental impact statement-construction permit, early site permit, or combined license.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... required. 5 The impact statement shall take account of dose commitments and health effects from fuel cycle... the site proposed. The draft environmental impact statement must not include an assessment of the... certification environmental assessment, then the draft combined license environmental impact statement shall...

  7. Incentivizing Multiple Revisions Improves Student Writing without Increasing Instructor Workload

    ERIC Educational Resources Information Center

    Stellmack, Mark A.; Sandidge, Rita R.; Sippl, Amy L.; Miller, Danneka J.

    2015-01-01

    Previous research has shown that when students are required to submit a draft and a revision of their writing, large proportions of students do not improve across drafts. We implemented a writing assignment in which students were permitted to submit up to four optional drafts. To encourage substantive revisions, students were awarded additional…

  8. 77 FR 37058 - Draft Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ...] Draft Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance... availability of the draft guidance entitled ``Class II Special Controls Guidance Document: Implanted Blood... blood access devices may comply with the requirement of special controls for class II devices. This...

  9. National Evaluation of Title III Implementation Supplemental Report: Exploring Approaches to Setting English Language Proficiency Performance Criteria and Monitoring English Learner Progress. Draft

    ERIC Educational Resources Information Center

    Cook, Gary; Linquanti, Robert; Chinen, Marjorie; Jung, Hyekyung

    2012-01-01

    The Elementary and Secondary Education Act (ESEA), as amended by the No Child Left Behind Act of 2001 inaugurated important changes in assessment and accountability for English Learner (EL) students. Specifically, Title III of the law required states to develop or adopt English-language proficiency (ELP) standards aligned with language demands of…

  10. Mo 99 Draft Report.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seestrom, Susan Joyce

    The Nuclear Science Advisory Committee (NSAC) 99Molybdenum ( 99Mo) Subcommittee met December 14-15, 2017 to address the charge to NSAC requesting that a fourth annual review of the National Nuclear Security Administration (NNSA) 99Mo program be performed. The Subcommittee found that the NNSA has continued to make progress over the course of the year based on the specific American Medical Isotopes Production Act of 2012 (AMIPA) requirements.

  11. It's Time to Develop a New "Draft Test Protocol" for a Mars Sample Return Mission (or Two…).

    PubMed

    Rummel, John D; Kminek, Gerhard

    2018-04-01

    The last time NASA envisioned a sample return mission from Mars, the development of a protocol to support the analysis of the samples in a containment facility resulted in a "Draft Test Protocol" that outlined required preparations "for the safe receiving, handling, testing, distributing, and archiving of martian materials here on Earth" (Rummel et al., 2002 ). This document comprised a specific protocol to be used to conduct a biohazard test for a returned martian sample, following the recommendations of the Space Studies Board of the US National Academy of Sciences. Given the planned launch of a sample-collecting and sample-caching rover (Mars 2020) in 2 years' time, and with a sample return planned for the end of the next decade, it is time to revisit the Draft Test Protocol to develop a sample analysis and biohazard test plan to meet the needs of these future missions. Key Words: Biohazard detection-Mars sample analysis-Sample receiving facility-Protocol-New analytical techniques-Robotic sample handling. Astrobiology 18, 377-380.

  12. 77 FR 39959 - Draft Guidance To Implement Requirements for the Treatment of Air Quality Monitoring Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    ... of the revised draft High Winds Guidance document, the EPA identifies example technical analyses that... identified analyses and any additional technical analyses that air agencies could use to demonstrate that the... Web site at http://www.epa.gov/ttn/analysis/exevents.htm for additional details on the draft non...

  13. 10 CFR 1021.213 - Rulemaking.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... comments, as part of the administrative record (40 CFR 1505.1(c)). (d) If an EIS is required, DOE will normally publish the draft EIS at the time it publishes the proposed rule (40 CFR 1502.5(d)). DOE will... draft EIS under § 1021.313 of this part. The draft EIS need not accompany notices of inquiry or advance...

  14. Would a Draft Save the Navy Money? A New Look.

    DTIC Science & Technology

    1983-07-01

    incentives to meet stipulated manning objectives (52,200 4YO accessions annually of whom 70 percent m be HSDGs). (4) 70 percent of draft-induced accessions...savings by as much as two- thirds at any given percentage of 4YO accessions who are draft -induced. Recall that in these calculations we assume: (a) a...percent for each percent of 4YO accession require- ments who are draft induced. Yet only about 60 percent of the Navy’s total annual HSDG accession

  15. 76 FR 71044 - International Conference on Harmonisation; E2B(R3) Electronic Transmission of Individual Case...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0720...; Draft Guidance on Implementation; Data Elements and Message Specification; Appendix on Backwards and...): Implementation Guide--Data Elements and Message Specification'' (the draft E2B(R3) implementation guidance) and...

  16. 77 FR 3777 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... Potassium (multiple RLDs) Aripiprazole Aspirin; Butalbital; Caffeine (multiple RLDs) Aspirin; Dipyridamole Aspirin; Oxycodone Aspirin; Butalbital; Caffeine; Codeine Phosphate Atovaquone Auranofin Azelaic Acid...

  17. 77 FR 31408 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ..., Washington, DC 20549-0213. Extension: Rules 17h-1T and 17h-2T, SEC File No. 270-359, OMB Control No. 3235... are approximately twenty-five new respondents per year that must draft an organizational chart... estimates that drafting the required organizational chart requires one hour and establishing a system for...

  18. Surface transportation weather decision support requirements : operational concept description : advanced-integrated decision support using weather information for surface transportation decisions makers : draft version 2.0

    DOT National Transportation Integrated Search

    2000-07-14

    This is a draft document for the Surface Transportation Weather Decision Support Requirements (STWDSR) project. The STWDSR project is being conducted for the FHWAs Office of Transportation Operations (HOTO) Road Weather Management Program by Mitre...

  19. A Space-Based Point Design for Global Coherent Doppler Wind Lidar Profiling Matched to the Recent NASA/NOAA Draft Science Requirements

    NASA Technical Reports Server (NTRS)

    Kavaya, Michael J.; Emmitt, G. David; Frehlich, Rod G.; Amzajerdian, Farzin; Singh, Upendra N.

    2002-01-01

    An end-to-end point design, including lidar, orbit, scanning, atmospheric, and data processing parameters, for space-based global profiling of atmospheric wind will be presented. The point design attempts to match the recent NASA/NOAA draft science requirements for wind measurement.

  20. 33 CFR 157.10c - Segregated ballast tanks, crude oil washing systems, and dedicated clean ballast tanks for...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... to meet the draft and trim requirements in § 157.09(b); or (2) A crude oil washing system that meets... trim requirements in § 157.09(b); or (2) Dedicated clean ballast tanks that meet the design and... meet the draft and trim requirements in § 157.09(b). (d) If the arrangement of tanks on a vessel under...

  1. 33 CFR 157.10c - Segregated ballast tanks, crude oil washing systems, and dedicated clean ballast tanks for...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to meet the draft and trim requirements in § 157.09(b); or (2) A crude oil washing system that meets... trim requirements in § 157.09(b); or (2) Dedicated clean ballast tanks that meet the design and... meet the draft and trim requirements in § 157.09(b). (d) If the arrangement of tanks on a vessel under...

  2. 78 FR 68447 - Exposure Draft-Standards for Internal Control in the Federal Government

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-14

    ... Federal Government reflect major developments in the accountability and financial management profession and emphasize specific considerations applicable to the government environment. The draft of the...

  3. Draft Environmental Impact Report/Environmental Impact Statement. Cullinan Ranch Specific Plan.

    DTIC Science & Technology

    1983-05-01

    COMMITMENTS OF RESOURCES WHICH WOULD BE INVOLVED IN THE PROPOSED ACTION SHOULD IT BE IMPLEMENTED 150 VII. GROWTH -INDUCING IMPACTS OF THE PROPOSED ACTION 151... conditions Involving soft bay mud and peat deposits, and 3) raise the surface level of the project to accnmmodate planned settlement and provide...data becomes available. These issues are indicated with an asterisk (*). 1. Growth inducement with required expansion of Infrastructure to support

  4. Cargo Movement Operations System (CMOS) Updated Draft Software Requirements Specification (Applications CSCI) Increment II

    DTIC Science & Technology

    1990-11-29

    appropriate to combine them into one paragraph. CMOS PMO ACCEPTS COY24ENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT...COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [ ] CLOSED [ ] ORIGINATOR CONTROL NUMBER: SRS1-0004...ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [ ] CLOSED [ ] ORIGINATOR CONTROL NUMBER: SRS1-0005 PROGRAM OFFICE

  5. 75 FR 50008 - Notice of Availability of a Draft Site-Specific Environmental Assessment and Notice of Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... and locations of the public hearings for this Draft SSEA. An open house session will precede the... information presented in the Draft SSEA. NSF representatives will be available during the open house sessions... an open house session from X p.m. to X p.m. A presentation and formal public comment period will be...

  6. 40 CFR 60.1080 - Where and when must I hold a public meeting on my draft materials separation plan?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... meeting on my draft materials separation plan? 60.1080 Section 60.1080 Protection of Environment... Preconstruction Requirements: Materials Separation Plan § 60.1080 Where and when must I hold a public meeting on my draft materials separation plan? (a) You must hold a public meeting and accept comments on your...

  7. 40 CFR 60.1080 - Where and when must I hold a public meeting on my draft materials separation plan?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... meeting on my draft materials separation plan? 60.1080 Section 60.1080 Protection of Environment... Preconstruction Requirements: Materials Separation Plan § 60.1080 Where and when must I hold a public meeting on my draft materials separation plan? (a) You must hold a public meeting and accept comments on your...

  8. 40 CFR 60.1080 - Where and when must I hold a public meeting on my draft materials separation plan?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... meeting on my draft materials separation plan? 60.1080 Section 60.1080 Protection of Environment... Preconstruction Requirements: Materials Separation Plan § 60.1080 Where and when must I hold a public meeting on my draft materials separation plan? (a) You must hold a public meeting and accept comments on your...

  9. 40 CFR 60.1080 - Where and when must I hold a public meeting on my draft materials separation plan?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... meeting on my draft materials separation plan? 60.1080 Section 60.1080 Protection of Environment... Preconstruction Requirements: Materials Separation Plan § 60.1080 Where and when must I hold a public meeting on my draft materials separation plan? (a) You must hold a public meeting and accept comments on your...

  10. 40 CFR 60.1080 - Where and when must I hold a public meeting on my draft materials separation plan?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... meeting on my draft materials separation plan? 60.1080 Section 60.1080 Protection of Environment... Preconstruction Requirements: Materials Separation Plan § 60.1080 Where and when must I hold a public meeting on my draft materials separation plan? (a) You must hold a public meeting and accept comments on your...

  11. Compensatory Mitigation Rule Draft Environmental Assessment

    EPA Pesticide Factsheets

    Draft Compensatory Mitigation Rule intended to promote regulatory efficiency by establishing standards and criteria that would apply to compensatory mitigation required for DA permits issued under Section 404 of the Clean Water Act.

  12. 77 FR 44699 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ..., Washington, DC 20549-0213. Extension: Rules 17h-1T and 17h-2T, SEC File No. 270-359, OMB Control No. 3235... that must draft an organizational chart required under Rule 17h-1T and establish a system for complying with the risk assessment rules. The staff estimates that drafting the required organizational chart...

  13. Optimal Draft requirement for vibratory tillage equipment using Genetic Algorithm Technique

    NASA Astrophysics Data System (ADS)

    Rao, Gowripathi; Chaudhary, Himanshu; Singh, Prem

    2018-03-01

    Agriculture is an important sector of Indian economy. Primary and secondary tillage operations are required for any land preparation process. Conventionally different tractor-drawn implements such as mouldboard plough, disc plough, subsoiler, cultivator and disc harrow, etc. are used for primary and secondary manipulations of soils. Among them, oscillatory tillage equipment is one such type which uses vibratory motion for tillage purpose. Several investigators have reported that the requirement for draft consumption in primary tillage implements is more as compared to oscillating one because they are always in contact with soil. Therefore in this paper, an attempt is made to find out the optimal parameters from the experimental data available in the literature to obtain minimum draft consumption through genetic algorithm technique.

  14. A FRAME response to the Draft Report on Alternative (Non-animal) Methods for Cosmetics Testing: Current Status and Future Prospects--2010.

    PubMed

    Balls, Michael; Clothier, Richard

    2010-10-01

    This response on behalf of FRAME to the European Commission's consultation on the five chapters of the Draft Report on Alternative (Non-animal) Methods for Cosmetics Testing: Current Status and Future Prospects--2010, is via a Comment in ATLA, rather than via the template supplied by the Commission. This is principally so that a number of general points about cosmetic ingredient testing can be made. It is concluded that the five draft chapters do not provide a credible basis for the Commission's forthcoming report to the European Parliament and the European Council on the five cosmetic ingredient safety issues for which the 7th Amendment to the Cosmetic Directive's ban on animal testing was postponed until 2013. This is mainly because there is insufficient focus in the draft chapters on the specific nature of cosmetic ingredients, their uses, their local effects and metabolism at their sites of application, and, in particular, on whether their possible absorption into the body would be likely to lead to their accumulation in target sites at levels approaching Thresholds of Toxicological Concern. Meanwhile, there continues to be uncertainty about how the provisions of the Cosmetics Directive should be applied, given the requirements of the REACH system and directives concerned with the safety of other chemicals and products. © 2010 FRAME.

  15. 78 FR 52532 - Exposure Draft-Standards for Internal Control in the Federal Government

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... developments in the accountability and financial management profession and emphasize specific considerations applicable to the government environment. The draft of the proposed changes to Standards for Internal Control...

  16. Draft Site Treatment Plan (DSTP), Volumes I and II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D`Amelio, J.

    1994-08-30

    Site Treatment Plans (STP) are required for facilities at which the DOE generates or stores mixed waste. This Draft Site Treatment Plan (DSTP) the second step in a three-phase process, identifies the currently preferred options for treating mixed waste at the Savannah River Site (SRS) or for developing treatment technologies where technologies do not exist or need modification. The DSTP reflects site-specific preferred options, developed with the state`s input and based on existing available information. To the extent possible, the DSTP identifies specific treatment facilities for treating the mixed waste and proposes schedules. Where the selection of specific treatment facilitiesmore » is not possible, schedules for alternative activities such as waste characterization and technology assessment are provided. All schedule and cost information presented is preliminary and is subject to change. The DSTP is comprised of two volumes: this Compliance Plan Volume and the Background Volume. This Compliance Plan Volume proposes overall schedules with target dates for achieving compliance with the land disposal restrictions (LDR) of RCRA and procedures for converting the target dates into milestones to be enforced under the Order. The more detailed discussion of the options contained in the Background Volume is provided for informational purposes only.« less

  17. Redmedial Action, Decision Document, Leaseback Area, Alabama Army Ammunition Plant

    DTIC Science & Technology

    1988-02-01

    Draft Report, Environmental Science and Engineering, Inc. (ESE), 1980. o Final Report for the Alabama Army Ammunition Plant, Leaseback Area...Requirements for the GSA and Leaseback Areas at the AAAP, Draft Report. Environmental Science and Engineering, Inc.(ESE), 1980. o Alabama Army...Ammunition Plant, Feasibility Study, Draft Report, Environmental Science and Engineering, Inc. (ESE), 1986. o Environmental Survey of Alabama Army Ammunition

  18. OVERVIEW OF THE DRAFT METHODOLOGY FOR CONDUCTING BIOLOGICAL EVALUATIONS OF AQUATIC LIFE CRITERIA

    EPA Science Inventory

    This presentation will provide an overview of the draft methodology used in developing biological evaluations of aquatic life criteria specifically addressing aquatic and aquatic-dependent threatened and endangered species.

  19. Do It Right! Requiring Multiple Submissions of Math and NMR Analysis Assignments in the Laboratory

    ERIC Educational Resources Information Center

    Slade, David J.

    2017-01-01

    The first-semester introductory organic chemistry laboratory has been adapted to include mini postlab assignments that students must complete correctly, through as many attempts as prove to be necessary. The use of multiple drafts of writing assignments is a standard approach to improving writing, so the system was designed to require drafts for…

  20. Defense Acquisition Review Journal. Volume 17, Number 1, Issue 53

    DTIC Science & Technology

    2010-01-01

    2010 | 1 5 0 stYle We will require you to submit your final draft of the manuscript, especially citations (endnotes instead of footnotes), in the...format specified in two specific style manuals. The ARJ follows the author (date) form of citation . We expect you to use the Publication Manual of the...a reference librarian in completing citation of government documents because standard formulas of citations may provide incomplete information in

  1. Defense AR Journal. Issue 56, Volume 17, Number 4. Measuring Programs and Progress

    DTIC Science & Technology

    2010-10-01

    5 2 3 styLe We will require you to submit your final draft of the manuscript, especially citations (endnotes instead of footnotes), in the format...specified in two specific style manuals. The ARJ follows the author (date) form of citation . We expect you to use the Publication Manual of the...reference librarian in completing citation of government documents because standard formulas of citations may provide incomplete information in reference

  2. 76 FR 57031 - Draft Harmonized Test Guidelines; Notice of Availability and Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ...EPA is announcing the availability of the draft test guidelines for Series 810--Product Performance Test Guidelines for Public Health Uses of Antimicrobial Agents, concerning specifically air, textiles, and water.

  3. Draft Maumee River Watershed Restoration Plan

    EPA Pesticide Factsheets

    A draft of the Maumee River AOC Watershed Restoration Plan was completed in January 2006. The plan was created to meet requirements for the stage II RAP as well as Ohio EPA’s and ODNR’s Watershed Coordinator Program.

  4. How Biomechanical Improvements in Running Economy Could Break the 2-hour Marathon Barrier.

    PubMed

    Hoogkamer, Wouter; Kram, Rodger; Arellano, Christopher J

    2017-09-01

    A sub-2-hour marathon requires an average velocity (5.86 m/s) that is 2.5% faster than the current world record of 02:02:57 (5.72 m/s) and could be accomplished with a 2.7% reduction in the metabolic cost of running. Although supporting body weight comprises the majority of the metabolic cost of running, targeting the costs of forward propulsion and leg swing are the most promising strategies for reducing the metabolic cost of running and thus improving marathon running performance. Here, we calculate how much time could be saved by taking advantage of unconventional drafting strategies, a consistent tailwind, a downhill course, and specific running shoe design features while staying within the current International Association of Athletic Federations regulations for record purposes. Specifically, running in shoes that are 100 g lighter along with second-half scenarios of four runners alternately leading and drafting, or a tailwind of 6.0 m/s, combined with a 42-m elevation drop could result in a time well below the 2-hour marathon barrier.

  5. An Examination of the Perceived Importance of Technical Competence in Acquisition Project Management

    DTIC Science & Technology

    1991-09-01

    Develop (First Draft) Instructions Critique (Revision) Answerability Pilot Test (Second Draft) Analysis Response Mode Revision Useability Preparation...appropriate questionnaire items. Initially, the set of questions developed for the study reflected a few shortcomings. A pilot test of the first draft among...resulted. First, feedback from the pilot test indicated a need to reduce the completion time. Because the multiple choice format required several

  6. 75 FR 22162 - Draft NIJ Duty Holster Retention Standard for Law Enforcement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-27

    ...In an effort to obtain comments from interested parties, the U.S. Department of Justice, Office of Justice Programs, National Institute of Justice will make available to the general public two draft documents: (1) A draft standard entitled, ``NIJ Duty Holster Retention Standard for Law Enforcement'' and (2) a draft companion document entitled, ``NIJ Duty Holster Retention Certification Program Requirements.'' The opportunity to provide comments on these two documents is open to industry technical representatives, law enforcement agencies and organizations, research, development and scientific communities, and all other stakeholders and interested parties. Those individuals wishing to obtain and provide comments on the draft documents under consideration are directed to the following Web site: http://www.justnet.org.

  7. Design optimization of hydraulic turbine draft tube based on CFD and DOE method

    NASA Astrophysics Data System (ADS)

    Nam, Mun chol; Dechun, Ba; Xiangji, Yue; Mingri, Jin

    2018-03-01

    In order to improve performance of the hydraulic turbine draft tube in its design process, the optimization for draft tube is performed based on multi-disciplinary collaborative design optimization platform by combining the computation fluid dynamic (CFD) and the design of experiment (DOE) in this paper. The geometrical design variables are considered as the median section in the draft tube and the cross section in its exit diffuser and objective function is to maximize the pressure recovery factor (Cp). Sample matrixes required for the shape optimization of the draft tube are generated by optimal Latin hypercube (OLH) method of the DOE technique and their performances are evaluated through computational fluid dynamic (CFD) numerical simulation. Subsequently the main effect analysis and the sensitivity analysis of the geometrical parameters of the draft tube are accomplished. Then, the design optimization of the geometrical design variables is determined using the response surface method. The optimization result of the draft tube shows a marked performance improvement over the original.

  8. Layered Electrical Product Application Protocol (AP). Draft: Initial Graphics Exchange Specification (IGES)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1994-09-01

    An application protocol is an information systems engineering view of a specific product. The view represents an agreement on the generic activities needed to design and fabricate the product, the agreement on the information needed to support those activities, and the specific constructs of a product data standard for use in transfering some or all of the information required. This applications protocol describes the data for electrical and electronic products in terms of a product description standard called the Initial Graphics Exchange Specification (IGES). More specifically, the Layered Electrical Product IGES Application Protocol (AP) specifies the mechanisms for defining andmore » exchanging computer-models and their associated data for those products which have been designed in two dimensional geometry so as to be produced as a series of layers in IGES format. The AP defines the appropriateness of the data items for describing the geometry of the various parts of a product (shape and location), the connectivity, and the processing and material characteristics. Excluded is the behavioral requirements which the product was intended to satisfy, except as those requirements have been recorded as design rules or product testing requirements.« less

  9. Draft Genome Sequences of Two Species of "Difficult-to-Identify" Human-Pathogenic Corynebacteria: Implications for Better Identification Tests.

    PubMed

    Pacheco, Luis G C; Mattos-Guaraldi, Ana L; Santos, Carolina S; Veras, Adonney A O; Guimarães, Luis C; Abreu, Vinícius; Pereira, Felipe L; Soares, Siomar C; Dorella, Fernanda A; Carvalho, Alex F; Leal, Carlos G; Figueiredo, Henrique C P; Ramos, Juliana N; Vieira, Veronica V; Farfour, Eric; Guiso, Nicole; Hirata, Raphael; Azevedo, Vasco; Silva, Artur; Ramos, Rommel T J

    2015-01-01

    Non-diphtheriae Corynebacterium species have been increasingly recognized as the causative agents of infections in humans. Differential identification of these bacteria in the clinical microbiology laboratory by the most commonly used biochemical tests is challenging, and normally requires additional molecular methods. Herein, we present the annotated draft genome sequences of two isolates of "difficult-to-identify" human-pathogenic corynebacterial species: C. xerosis and C. minutissimum. The genome sequences of ca. 2.7 Mbp, with a mean number of 2,580 protein encoding genes, were also compared with the publicly available genome sequences of strains of C. amycolatum and C. striatum. These results will aid the exploration of novel biochemical reactions to improve existing identification tests as well as the development of more accurate molecular identification methods through detection of species-specific target genes for isolate's identification or drug susceptibility profiling.

  10. 75 FR 41923 - Public Meeting on Draft Recommendations for Safely Transporting Children in Specific Situations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ...) protect the head, neck and spine of all children transported in ground ambulances. By ensuring that these... transport (newborn with Mother, multiple children, etc.). The full text of the recommendations and the draft...

  11. 78 FR 55263 - Draft Guidance for Industry on Bioequivalence Recommendations for Fluticasone Propionate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ...] Draft Guidance for Industry on Bioequivalence Recommendations for Fluticasone Propionate; Salmeterol... ``Bioequivalence Recommendations for Fluticasone Propionate; Salmeterol Xinafoate.'' The recommendations provide specific guidance on the design of bioequivalence (BE) studies to support abbreviated new drug applications...

  12. 15 CFR 923.60 - Review/approval procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE... management program are not required, OCRM will prepare draft and final environmental impact statements, in... preparation and dissemination of draft and final environmental impact statements and lengthy Federal agency...

  13. Industrial Orientation.

    ERIC Educational Resources Information Center

    Rasor, Leslie; Brooks, Valerie

    These eight modules for an industrial orientation class were developed by a project to design an interdisciplinary program of basic skills training for disadvantaged students in a Construction Technology Program (see Note). The Drafting module overviews drafting career opportunities, job markets, salaries, educational requirements, and basic…

  14. DOD Information Technology Standard Guidance (ITSG) Version 3.1

    DTIC Science & Technology

    1997-04-07

    from NGSBs later (e.g., OSFs Motif specification became the basis for IEEE 1295 . 1). Most consortia specifications are available now, do not overlap...Illumination) CIM Center for Information Management (DISA) CINC Conumnder in Chief CIS CASE Integration Services CJCS Chairman of the Joint Chiefs of...Compound Text Encoding CUA Common User Access DAC Discretionary Access Controls DAD Draft Addendum (ISO) DAM Draft Amendment (ISO) DAP Document

  15. Plant Habitat Telemetry / Command Interface and E-MIST

    NASA Technical Reports Server (NTRS)

    Walker, Uriae M.

    2013-01-01

    Plant Habitat (PH) is an experiment to be taken to the International Space Station (ISS) in 2016. It is critical that ground support computers have the ability to uplink commands to control PH, and that ISS computers have the ability to downlink PH telemetry data to ground support. This necessitates communication software that can send, receive, and process, PH specific commands and telemetry. The objective of the Plant Habitat Telemetry/ Command Interface is to provide this communication software, and to couple it with an intuitive Graphical User Interface (GUI). Initial investigation of the project objective led to the decision that code be written in C++ because of its compatibility with existing source code infrastructures and robustness. Further investigation led to a determination that multiple Ethernet packet structures would need to be created to effectively transmit data. Setting a standard for packet structures would allow us to distinguish these packets that would range from command type packets to sub categories of telemetry packets. In order to handle this range of packet types, the conclusion was made to take an object-oriented programming approach which complemented our decision to use the C++ programming language. In addition, extensive utilization of port programming concepts was required to implement the core functionality of the communication software. Also, a concrete understanding of a packet processing software was required in order to put aU the components of ISS-to-Ground Support Equipment (GSE) communication together and complete the objective. A second project discussed in this paper is Exposing Microbes to the Stratosphere (EMIST). This project exposes microbes into the stratosphere to observe how they are impacted by atmospheric effects. This paper focuses on the electrical and software expectations of the project, specifically drafting the printed circuit board, and programming the on-board sensors. The Eagle Computer-Aided Drafting (CAD) software was used to draft the E-MIST circuit. This required several component libraries to be created. Coding the sensors and obtaining sensor data involved using the Arduino Uno developmental board and coding language, and properly wiring peripheral sensors to the microcontroller (the central control unit of the experiment).

  16. 76 FR 38187 - International Conference on Harmonisation; Draft Guidance on Q11 Development and Manufacture of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ...The Food and Drug Administration (FDA) is announcing the availability of a draft guidance entitled ``Q11 Development and Manufacture of Drug Substances.'' The draft guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The draft guidance describes approaches to developing process and drug substance understanding and provides guidance on what information should be provided in certain sections of the Common Technical Document (CTD). The draft guidance is intended to harmonize the scientific and technical principles relating to the description and justification of the development and manufacturing process of drug substances (both chemical entities and biotechnological/biological entities) to enable a consistent approach for providing and evaluating this information across the three regions.

  17. IRIS Toxicological Review of Diisononyl Phthalate (Dinp) (Preliminary Assessment Materials)

    EPA Science Inventory

    In August 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for DINP to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in ...

  18. IRIS Toxicological Review of Inorganic Arsenic (Preliminary Assessment Materials)

    EPA Science Inventory

    In April 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for inorganic arsenic (iAs) to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA ...

  19. IRIS Toxicological Review of Dibutyl Phthalate (Dbp) (Preliminary Assessment Materials)

    EPA Science Inventory

    In January 2015, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for DBP to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in ...

  20. Draft Test Guideline: Site-Specific Aquatic Microcosm Test, Laboratory

    EPA Pesticide Factsheets

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  1. IRIS Toxicological Review of Diisobutyl Phthalate (Dibp) (Preliminary Assessment Materials)

    EPA Science Inventory

    In September 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for DIBP to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested ...

  2. IRIS Toxicological Review of Hexabromocyclododecane (HBCD) (Preliminary Assessment Materials)

    EPA Science Inventory

    In March 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for HBCD to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in c...

  3. Actual issues of introduction of continuous emission monitoring systems for control of negative impact of TPP to atmospheric air

    NASA Astrophysics Data System (ADS)

    Kondrateva, O. E.; Roslyakov, P. V.; Borovkova, A. M.; Loktionov, O. A.

    2017-11-01

    Over the past 3 years there have been significant changes in Russian environmental legislation related to the transition to technological regulation based on the principles of the best available technologies (BAT). These changes also imply control and accounting of the harmful impact of industrial enterprises on the environment. Therefore, a mandatory requirement for equipping automatic continuous emission monitoring systems (ACEMS) is established for all large TPPs. For a successful practical solution of the problem of introducing such systems in the whole country there is an urgent need to develop the governing regulatory document for the design and operation of systems for continuous monitoring of TPP emissions into the air, allowing within reasonable limits to unify these systems for their work with the state data fund of state environmental monitoring and make easier the process of their implementation at operating facilities for industrial enterprises. Based on the large amount of research in the field of creation of ACEMS, which conducted in National Research University “MPEI”, a draft guidance document was developed, which includes the following regulatory provisions: goals and objectives of ACEMS, the stages of their introduction rules of carrying out preliminary inspection of energy facilities, requirements to develop technical specifications, general requirements for the operation of ACEMS, requirements to the structure and elements of ACEMS, recommendations on selection of places of measuring equipment installation, rules for execution, commissioning and acceptance testing, continuous measurement method, method for determination of the current gross and specific emissions. The draft guidance document, developed by the National Research University “MPEI”, formed the basis of the Preliminary national standards PNST 187-2017 “Automatic systems for continuous control and metering of contaminants emissions from thermal electric power stations into the atmospheric air. General requirements”. [1

  4. Nanomaterial Case Study: Nanoscale Silver in Disinfectant Spray (External Review Draft)

    EPA Science Inventory

    This draft document presents a case study of engineered nanoscale silver (nano-Ag), focusing on the specific example of nano-Ag as possibly used in disinfectant sprays. This case study is organized around a comprehensive environmental assessment (CEA) framework, which combines a ...

  5. IRIS Toxicological Review of Diethyl Phthalate (DEP) (Preliminary Assessment Materials)

    EPA Science Inventory

    In March 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for DEP to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in co...

  6. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (Preliminary Assessment Materials)

    EPA Science Inventory

    In August 2013, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for ETBE to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in ...

  7. IRIS Toxicological Review of Butyl Benzyl Phthalate (Bbp) (Preliminary Assessment Materials)

    EPA Science Inventory

    In September 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for BBP to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested i...

  8. NPDES Draft Permit for Dakota Magic Casino Wastewater Treatment Facility in North Dakota

    EPA Pesticide Factsheets

    Under NPDES draft permit ND0030813, the Dakota Magic Hotel and Casino WWTF is authorized to discharge, in accordance with the requirements as contained in the provisions of this Permit, from its wastewater treatment facility to the Bois de Sioux.

  9. 40 CFR 1506.3 - Adoption.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) An agency may adopt a Federal draft or final environmental impact statement or portion thereof... are substantially the same, the agency adopting another agency's statement is not required to recirculate it except as a final statement. Otherwise the adopting agency shall treat the statement as a draft...

  10. Draft Permit & Supporting Documentation for the Cape Wind Associates, LLC, Horseshoe Shoal, Nantucket Sound (Offshore Renewable Energy Project/OCS Air Permit)

    EPA Pesticide Factsheets

    List of draft permit & supporting documentation for the Cape Wind Associates, LLC, Horseshoe Shoal, Nantucket Sound (Offshore Renewable Energy Project/OCS Air Permit: Massachusetts Plan Approval including nonattainment NSR Appendix A requirements).

  11. Telescience Testbed Pilot Program

    NASA Technical Reports Server (NTRS)

    Gallagher, Maria L. (Editor); Leiner, Barry M. (Editor)

    1988-01-01

    The Telescience Testbed Pilot Program is developing initial recommendations for requirements and design approaches for the information systems of the Space Station era. During this quarter, drafting of the final reports of the various participants was initiated. Several drafts are included in this report as the University technical reports.

  12. 77 FR 1717 - Notice of Availability; Draft Springfield Plateau Regional Restoration Plan and Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ... Resources, have written a Draft Springfield Plateau Regional Restoration Plan and Environmental Assessment... Plateau ecoregion, and an environmental assessment, as required pursuant to the National Environmental... Springfield Plateau Regional Restoration Plan and Environmental Assessment will be finalized prior to...

  13. 77 FR 66483 - Public Comment on the Draft Federal Urban Design Element and the Draft Update to the Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-05

    ... NCPC review required by law. The new Federal Urban Design Element provides policies that will guide the... Historic Features Element will be available online at http://www.ncpc.gov/compplan not later than November...

  14. Government Information Locator Service (GILS). Draft report to the Information Infrastructure Task Force

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This is a draft report on the Government Information Locator Service (GILS) to the National Information Infrastructure (NII) task force. GILS is designed to take advantage of internetworking technology known as client-server architecture which allows information to be distributed among multiple independent information servers. Two appendices are provided -- (1) A glossary of related terminology and (2) extracts from a draft GILS profile for the use of the American National Standard Information Retrieval Application Service Definition and Protocol Specification for Library Applications.

  15. Potential System Integration Issues in the Joint Multi-Role (JMR) Joint Common Architecture (JCA) Demonstration System

    DTIC Science & Technology

    2015-12-01

    the MIS System/Subsystem Specification ( SSS ), and supplementary BAA document. On June 26, 2014, the SEI provided a draft interim report of the...findings and issues. The SEI team also received July 3, 2014, versions of the MIS Stakeholder Requirements, MIS SSS , and build plan and July 17, 2014...versions of the MIS SSS together with the MIS system model. On July 14–15, 2014, the SEI presented a summary of the issues at the two contractors

  16. 77 FR 18827 - Draft Guidance for Industry on Bioequivalence Recommendations for Iron Sucrose Injection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ...] Draft Guidance for Industry on Bioequivalence Recommendations for Iron Sucrose Injection; Availability... Recommendations for Iron Sucrose.'' The recommendations provide specific guidance on the design of bioequivalence (BE) studies to support abbreviated new drug applications (ANDAs) for iron sucrose injection. DATES...

  17. 78 FR 75579 - License Renewal Application for Grand Gulf Nuclear Station, Unit 1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ... NUCLEAR REGULATORY COMMISSION [Docket No. 50-416; NRC-2011-0262] License Renewal Application for Grand Gulf Nuclear Station, Unit 1 AGENCY: Nuclear Regulatory Commission. ACTION: Draft supplemental....S. Nuclear Regulatory Commission (NRC) is issuing for public comment a draft, plant-specific...

  18. IRIS Toxicological Review of Tert-Butyl Alcohol (Tert-Butanol) (Preliminary Assessment Materials)

    EPA Science Inventory

    In August 2013, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for TBA to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in c...

  19. Regulatory Forum Opinion Piece: Review of FDA Draft Guidance Testicular Toxicity-Evaluation during Drug Development Guidance for Industry.

    PubMed

    Hukkanen, Renee R; Halpern, Wendy G; Vidal, Justin D

    2016-10-01

    In July 2015, the U.S. Food and Drug Administration (FDA) posted a new draft guidance entitled "Testicular Toxicity: Evaluation during Drug Development Guidance for Industry," with a 90-day public comment period. As the nonclinical assessment of testicular toxicity often relies on the expert interpretation of pathology affecting the male reproductive tract, this draft guidance is considered directly relevant to the toxicologic pathology community. Therefore, a working group was formed through the Scientific and Regulatory Policy Committee of the Society of Toxicologic Pathologists (STPs) to provide a detailed review of the draft guidance. Specific comments on the guidance were submitted to the FDA by the STP. The draft guidance and all comments received are currently under review with the FDA. This commentary provides a summary of the components of the draft guidance and the comments submitted by the STP with acknowledgment of different perspectives reflected in comments from other respondents. © The Author(s) 2016.

  20. 40 CFR 60.57b - Siting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...)(1)(ii) of this section. (i) The owner or operator shall distribute the preliminary draft materials... amount of waste generation anticipated for the service area. (C) The types and estimated amounts of... operator shall distribute the siting analysis and final draft materials separation plan to the principal...

  1. 40 CFR 60.57b - Siting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...)(1)(ii) of this section. (i) The owner or operator shall distribute the preliminary draft materials... amount of waste generation anticipated for the service area. (C) The types and estimated amounts of... operator shall distribute the siting analysis and final draft materials separation plan to the principal...

  2. 40 CFR 60.57b - Siting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...)(1)(ii) of this section. (i) The owner or operator shall distribute the preliminary draft materials... amount of waste generation anticipated for the service area. (C) The types and estimated amounts of... operator shall distribute the siting analysis and final draft materials separation plan to the principal...

  3. 40 CFR 60.57b - Siting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...)(1)(ii) of this section. (i) The owner or operator shall distribute the preliminary draft materials... amount of waste generation anticipated for the service area. (C) The types and estimated amounts of... operator shall distribute the siting analysis and final draft materials separation plan to the principal...

  4. 78 FR 3418 - Pesticides; Draft Guidance for Pesticide Registrants on Web-Distributed Labeling for Pesticide...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... with pesticide labeling requirements and thereby protecting human health and the environment from... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2012-0906; FRL-9374-4] Pesticides; Draft Guidance for Pesticide Registrants on Web- Distributed Labeling for Pesticide Products AGENCY: Environmental Protection...

  5. 78 FR 38092 - Notice of Availability of a Draft Environmental Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-25

    ... Environmental Assessment AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Availability of a Draft Environmental Assessment for the construction and operation of a replacement aerial tramway on... Environmental Assessment (DEA) in conformance with the requirements of the National Environmental Policy Act of...

  6. Integrated Computer-Aided Drafting Instruction (ICADI).

    ERIC Educational Resources Information Center

    Chen, C. Y.; McCampbell, David H.

    Until recently, computer-aided drafting and design (CAD) systems were almost exclusively operated on mainframes or minicomputers and their cost prohibited many schools from offering CAD instruction. Today, many powerful personal computers are capable of performing the high-speed calculation and analysis required by the CAD application; however,…

  7. Child-Resistant Packaging for E-Liquid: A Review of US State Legislation.

    PubMed

    Frey, Leslie T; Tilburg, William C

    2016-02-01

    A growing number of states have introduced or enacted legislation requiring child-resistant packaging for e-liquid containers; however, these laws involve varying terms, packaging standards, and enforcement provisions, raising concerns about their effectiveness. We evaluated bills against 4 benchmarks: broad product definitions that contemplate future developments in the market, citations to a specific packaging standard, stated penalties for violations, and express grants of authority to a state entity to enforce the packaging requirements. Our findings showed that 3 states meet all 4 benchmarks in their enacted legislation. We encourage states to consider these benchmarks when revising statutes or drafting future legislation.

  8. Child-Resistant Packaging for E-Liquid: A Review of US State Legislation

    PubMed Central

    Tilburg, William C.

    2016-01-01

    A growing number of states have introduced or enacted legislation requiring child-resistant packaging for e-liquid containers; however, these laws involve varying terms, packaging standards, and enforcement provisions, raising concerns about their effectiveness. We evaluated bills against 4 benchmarks: broad product definitions that contemplate future developments in the market, citations to a specific packaging standard, stated penalties for violations, and express grants of authority to a state entity to enforce the packaging requirements. Our findings showed that 3 states meet all 4 benchmarks in their enacted legislation. We encourage states to consider these benchmarks when revising statutes or drafting future legislation. PMID:26691114

  9. Multi-objective shape optimization of runner blade for Kaplan turbine

    NASA Astrophysics Data System (ADS)

    Semenova, A.; Chirkov, D.; Lyutov, A.; Chemy, S.; Skorospelov, V.; Pylev, I.

    2014-03-01

    Automatic runner shape optimization based on extensive CFD analysis proved to be a useful design tool in hydraulic turbomachinery. Previously the authors developed an efficient method for Francis runner optimization. It was successfully applied to the design of several runners with different specific speeds. In present work this method is extended to the task of a Kaplan runner optimization. Despite of relatively simpler blade shape, Kaplan turbines have several features, complicating the optimization problem. First, Kaplan turbines normally operate in a wide range of discharges, thus CFD analysis of each variant of the runner should be carried out for several operation points. Next, due to a high specific speed, draft tube losses have a great impact on the overall turbine efficiency, and thus should be accurately evaluated. Then, the flow in blade tip and hub clearances significantly affects the velocity profile behind the runner and draft tube behavior. All these features are accounted in the present optimization technique. Parameterization of runner blade surface using 24 geometrical parameters is described in details. For each variant of runner geometry steady state three-dimensional turbulent flow computations are carried out in the domain, including wicket gate, runner, draft tube, blade tip and hub clearances. The objectives are maximization of efficiency in best efficiency and high discharge operation points, with simultaneous minimization of cavitation area on the suction side of the blade. Multiobjective genetic algorithm is used for the solution of optimization problem, requiring the analysis of several thousands of runner variants. The method is applied to optimization of runner shape for several Kaplan turbines with different heads.

  10. CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes

    PubMed Central

    Parks, Donovan H.; Imelfort, Michael; Skennerton, Connor T.; Hugenholtz, Philip; Tyson, Gene W.

    2015-01-01

    Large-scale recovery of genomes from isolates, single cells, and metagenomic data has been made possible by advances in computational methods and substantial reductions in sequencing costs. Although this increasing breadth of draft genomes is providing key information regarding the evolutionary and functional diversity of microbial life, it has become impractical to finish all available reference genomes. Making robust biological inferences from draft genomes requires accurate estimates of their completeness and contamination. Current methods for assessing genome quality are ad hoc and generally make use of a limited number of “marker” genes conserved across all bacterial or archaeal genomes. Here we introduce CheckM, an automated method for assessing the quality of a genome using a broader set of marker genes specific to the position of a genome within a reference genome tree and information about the collocation of these genes. We demonstrate the effectiveness of CheckM using synthetic data and a wide range of isolate-, single-cell-, and metagenome-derived genomes. CheckM is shown to provide accurate estimates of genome completeness and contamination and to outperform existing approaches. Using CheckM, we identify a diverse range of errors currently impacting publicly available isolate genomes and demonstrate that genomes obtained from single cells and metagenomic data vary substantially in quality. In order to facilitate the use of draft genomes, we propose an objective measure of genome quality that can be used to select genomes suitable for specific gene- and genome-centric analyses of microbial communities. PMID:25977477

  11. CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes.

    PubMed

    Parks, Donovan H; Imelfort, Michael; Skennerton, Connor T; Hugenholtz, Philip; Tyson, Gene W

    2015-07-01

    Large-scale recovery of genomes from isolates, single cells, and metagenomic data has been made possible by advances in computational methods and substantial reductions in sequencing costs. Although this increasing breadth of draft genomes is providing key information regarding the evolutionary and functional diversity of microbial life, it has become impractical to finish all available reference genomes. Making robust biological inferences from draft genomes requires accurate estimates of their completeness and contamination. Current methods for assessing genome quality are ad hoc and generally make use of a limited number of "marker" genes conserved across all bacterial or archaeal genomes. Here we introduce CheckM, an automated method for assessing the quality of a genome using a broader set of marker genes specific to the position of a genome within a reference genome tree and information about the collocation of these genes. We demonstrate the effectiveness of CheckM using synthetic data and a wide range of isolate-, single-cell-, and metagenome-derived genomes. CheckM is shown to provide accurate estimates of genome completeness and contamination and to outperform existing approaches. Using CheckM, we identify a diverse range of errors currently impacting publicly available isolate genomes and demonstrate that genomes obtained from single cells and metagenomic data vary substantially in quality. In order to facilitate the use of draft genomes, we propose an objective measure of genome quality that can be used to select genomes suitable for specific gene- and genome-centric analyses of microbial communities. © 2015 Parks et al.; Published by Cold Spring Harbor Laboratory Press.

  12. 78 FR 46965 - Draft Guidance for Industry on Bioequivalence Recommendations for Mesalamine Rectal Suppositories...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... Recommendations for Mesalamine.'' The recommendations provide specific guidance on the design of bioequivalence... suppositories: A fasting BE study with pharmacokinetic endpoints and comparative in vitro studies (melting point...). The draft guidance, when finalized, will represent the Agency's current thinking on the design of BE...

  13. IRIS Toxicological Review of Hexavalent Chromium Part 2: Human, Toxicokinetic, and Mechanistic Studies (Preliminary Assessment Materials)

    EPA Science Inventory

    In August 2014, EPA released the second part of draft literature searches and associated search strategies, evidence tables, and exposure response arrays for Cr(VI) to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA w...

  14. Draft PRN 2006-A: Use of Antimicrobial Pesticide Products in Heating, Ventilation, Air Conditioning and Refrigeration Systems (HVAC&R)

    EPA Pesticide Factsheets

    This draft notice provides guidance to registrants of EPA-registered antimicrobial products whose labels bear general directions related to hard, non-porous or porous surfaces, but which are not but which are not specifically registered for HVAC uses.

  15. 75 FR 6018 - Environmental Management Site-Specific Advisory Board, Hanford

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-05

    ... in the Draft Tank Closure (TC) and Waste Management (WM) Environmental Impact Statement (EIS) Overview of the Draft TC and WM EIS findings by other stakeholder groups Discussion of HAB member comments on the TC and WM EIS Development of HAB advice principles Adjourn Public Participation: The meeting...

  16. IRIS Toxicological Review of Hexavalent Chromium Part 1: Experimental Animal Studies (Preliminary Assessment Materials)

    EPA Science Inventory

    In April 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for Cr(VI) to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in...

  17. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) (Preliminary Assessment Materials)

    EPA Science Inventory

    In August 2013, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for RDX to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in c...

  18. 77 FR 5415 - National Organic Program: Notice of Draft Guidance for Accredited Certifying Agents, Certified...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ... in order to be excluded from the organic certification requirements of Part 205. The NOSB recommended... handling operations that are or are not excluded from organic certification. The draft guidance proposes... excluded from certification and, therefore, must be certified organic operations. \\1\\ NOSB Recommendation...

  19. 46 CFR 61.35-3 - Required tests and checks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... heaters without water level controls) must be tested by interrupting the feed water supply. Manual reset... alarm and visible indicator must be verified. The shutdown times must be verified. (3) Fuel supply... draft loss interlock switch must be tested to ensure proper operation. The draft limit control must...

  20. Developmental Draft for Regents Chemistry Syllabus.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of General Education Curriculum Development.

    This booklet represents a developmental draft syllabus for Regents chemistry course in New York State. The introduction to the syllabus includes information about the prerequisites to the course, the teaching sequence, the laboratory procedure, the time requirement, and how to use the course for credit towards a State diploma. The syllabus is…

  1. The Cool Colors Project

    Science.gov Websites

    cool colored roofing for homes in California's 16 climates. Or, read our detailed draft report. To requirements for residential roofs in Title 24 [format: PDF]. Draft report presented at the California Energy presentation [format: PDF] summarizing this report. H. Akbari, C. Wray, T. Xu and R. Levinson. 2006. Inclusion

  2. 75 FR 18504 - International Cooperation on Harmonisation of Technical Requirements for Registration of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... Products (VICH). This draft VICH guidance document is intended to provide study design recommendations... Products; Draft Guidance for Industry on Studies to Evaluate the Metabolism and Residue Kinetics of Veterinary Drugs in Food-Producing Animals: Marker Residue Depletion Studies to Establish Product Withdrawal...

  3. Digital pathology: DICOM-conform draft, testbed, and first results.

    PubMed

    Zwönitzer, Ralf; Kalinski, Thomas; Hofmann, Harald; Roessner, Albert; Bernarding, Johannes

    2007-09-01

    Hospital information systems are state of the art nowadays. Therefore, Digital Pathology, also labelled as Virtual Microscopy, has gained increased attention. Triggered by radiology, standardized information models and workflows were world-wide defined based on DICOM. However, DICOM-conform integration of Digital Pathology into existing clinical information systems imposes new problems requiring specific solutions concerning the huge amount of data as well as the special structure of the data to be managed, transferred, and stored. We implemented a testbed to realize and evaluate the workflow of digitized slides from acquisition to archiving. The experiences led to the draft of a DICOM-conform information model that accounted for extensions, definitions, and technical requirements necessary to integrate digital pathology in a hospital-wide DICOM environment. Slides were digitized, compressed, and could be viewed remotely. Real-time transfer of the huge amount of data was optimized using streaming techniques. Compared to a recent discussion in the DICOM Working Group for Digital Pathology (WG26) our experiences led to a preference of a JPEG2000/JPIP-based streaming of the whole slide image. The results showed that digital pathology is feasible but strong efforts by users and vendors are still necessary to integrate Digital Pathology into existing information systems.

  4. Tax-exempt hospitals and community benefits: a review of state reporting requirements.

    PubMed

    Hellinger, Fred Joseph

    2009-02-01

    In June 2007 the Internal Revenue Service proposed a major overhaul of its reporting requirements for tax-exempt hospitals and released draft Form 990 (the IRS form filed by tax-exempt organizations each year). In December 2007 the IRS promulgated the final Form 990 after incorporating some of the recommendations made in the almost seven hundred public comments on the discussion draft. One recommendation adopted in the final Form 990 is the postponement until tax year 2009 (returns filed in 2010) of the requirement for hospitals to submit detailed information on the percentage of total expenses attributable to charity care, unreimbursed Medicaid costs, and community-health improvement programs (the discussion draft required this information for tax year 2007). Although the IRS will not require tax-exempt hospitals to provide detailed information about community benefits until the 2009 tax year, sixteen states have laws requiring tax-exempt hospitals to enumerate the benefits that they provide to the community. Information about the impact of these laws on the provision of community benefits (e.g., charity and uncompensated care) is examined in this study whose primary purpose is to highlight information policy makers may glean from states that have adopted community-benefit reporting laws.

  5. Draft sequencing and comparative genomics of Xylella fastidiosa strains reveal novel biological insights.

    PubMed

    Bhattacharyya, Anamitra; Stilwagen, Stephanie; Reznik, Gary; Feil, Helene; Feil, William S; Anderson, Iain; Bernal, Axel; D'Souza, Mark; Ivanova, Natalia; Kapatral, Vinayak; Larsen, Niels; Los, Tamara; Lykidis, Athanasios; Selkov, Eugene; Walunas, Theresa L; Purcell, Alexander; Edwards, Rob A; Hawkins, Trevor; Haselkorn, Robert; Overbeek, Ross; Kyrpides, Nikos C; Predki, Paul F

    2002-10-01

    Draft sequencing is a rapid and efficient method for determining the near-complete sequence of microbial genomes. Here we report a comparative analysis of one complete and two draft genome sequences of the phytopathogenic bacterium, Xylella fastidiosa, which causes serious disease in plants, including citrus, almond, and oleander. We present highlights of an in silico analysis based on a comparison of reconstructions of core biological subsystems. Cellular pathway reconstructions have been used to identify a small number of genes, which are likely to reside within the draft genomes but are not captured in the draft assembly. These represented only a small fraction of all genes and were predominantly large and small ribosomal subunit protein components. By using this approach, some of the inherent limitations of draft sequence can be significantly reduced. Despite the incomplete nature of the draft genomes, it is possible to identify several phage-related genes, which appear to be absent from the draft genomes and not the result of insufficient sequence sampling. This region may therefore identify potential host-specific functions. Based on this first functional reconstruction of a phytopathogenic microbe, we spotlight an unusual respiration machinery as a potential target for biological control. We also predicted and developed a new defined growth medium for Xylella.

  6. Draft versus finished sequence data for DNA and protein diagnostic signature development

    PubMed Central

    Gardner, Shea N.; Lam, Marisa W.; Smith, Jason R.; Torres, Clinton L.; Slezak, Tom R.

    2005-01-01

    Sequencing pathogen genomes is costly, demanding careful allocation of limited sequencing resources. We built a computational Sequencing Analysis Pipeline (SAP) to guide decisions regarding the amount of genomic sequencing necessary to develop high-quality diagnostic DNA and protein signatures. SAP uses simulations to estimate the number of target genomes and close phylogenetic relatives (near neighbors or NNs) to sequence. We use SAP to assess whether draft data are sufficient or finished sequencing is required using Marburg and variola virus sequences. Simulations indicate that intermediate to high-quality draft with error rates of 10−3–10−5 (∼8× coverage) of target organisms is suitable for DNA signature prediction. Low-quality draft with error rates of ∼1% (3× to 6× coverage) of target isolates is inadequate for DNA signature prediction, although low-quality draft of NNs is sufficient, as long as the target genomes are of high quality. For protein signature prediction, sequencing errors in target genomes substantially reduce the detection of amino acid sequence conservation, even if the draft is of high quality. In summary, high-quality draft of target and low-quality draft of NNs appears to be a cost-effective investment for DNA signature prediction, but may lead to underestimation of predicted protein signatures. PMID:16243783

  7. 78 FR 22269 - International Conference on Harmonisation; Draft Guidance on M7 Assessment and Control of DNA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ...The Food and Drug Administration (FDA) is announcing the availability of a draft guidance entitled ``M7 Assessment and Control of DNA Reactive (Mutagenic) Impurities in Pharmaceuticals to Limit Potential Carcinogenic Risk.'' The draft guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The draft guidance emphasizes considerations of both safety and quality risk management in establishing levels of mutagenic impurities that are expected to pose negligible carcinogenic risk. It outlines recommendations for assessment and control of mutagenic impurities that reside or are reasonably expected to reside in a final drug substance or product, taking into consideration the intended conditions of human use. The draft guidance is intended to provide guidance for new drug substances and new drug products during their clinical development and subsequent applications for marketing.

  8. Experimental investigation of the draft tube inlet flow of a bulb turbine

    NASA Astrophysics Data System (ADS)

    Vuillemard, J.; Aeschlimann, V.; Fraser, R.; Lemay, S.; Deschênes, C.

    2014-03-01

    In the BulbT project framework, a bulb turbine model was studied with a strongly diverging draft tube. At high discharge, flow separation occurs in the draft tube correlated to significant efficiency and power drops. In this context, a focus was put on the draft tube inlet flow conditions. Actually, a precise inlet flow velocity field is required for comparison and validation purposes with CFD simulation. This paper presents different laser Doppler velocimetry (LDV) measurements at the draft tube inlet and their analysis. The LDV was setup to measure the axial and circumferential velocity on a radius under the runner and a diameter under the hub. A method was developed to perform indirect measurement of the mean radial velocity component. Five operating conditions were studied to correlate the inlet flow to the separation in the draft tube. Mean velocities, fluctuations and frequencies allowed characterizing the flow. Using this experimental database, the flow structure was characterized. Phase averaged velocities based on the runner position allowed detecting the runner blade wakes. The velocity gradients induced by the blade tip vortices were captured. The guide vane wakes was also detected at the draft tube inlet. The recirculation in the hub wake was observed.

  9. Passenger Vessel Damage Stability Study for 1990 SOLAS Amendments. Volume 2. Appendix B

    DTIC Science & Technology

    1994-09-01

    0.1 Note: Drafts are measured at A.P. and F.P alang ship’s centertine GE SUMMARY (Bvaluated per IKO (SOLAB󈨞) Rules for Passenger Ships) Available...Drafts are measured at A.P. and F.P alang ship’s centertine 03 SUNMIRY (Nvaluated per liO (8OLA1󈨞) Rules for Passenger Ships) Available Required...156.0 ------------------------------------ i- ------------ Note: Drafts are mesured at A.P. and F.P alang ship’s center ,Irw GZ SUMMARY (2valuateG per

  10. Draft Genome Sequence of Staphylococcus aureus Strain HD1410, Isolated from a Persistent Nasal Carrier.

    PubMed

    Nurjadi, Dennis; Boutin, Sébastien; Dalpke, Alexander; Heeg, Klaus; Zanger, Philipp

    2018-05-10

    We report here the draft genome sequence of a Staphylococcus aureus strain isolated from the nares of an 18-year-old female healthy persistent-carrier individual, and it was used to investigate S. aureus -specific immune responses in colonized and noncolonized individuals. Copyright © 2018 Nurjadi et al.

  11. Draft Genome Sequence of Staphylococcus aureus Strain HD1410, Isolated from a Persistent Nasal Carrier

    PubMed Central

    Boutin, Sébastien; Dalpke, Alexander; Heeg, Klaus; Zanger, Philipp

    2018-01-01

    ABSTRACT We report here the draft genome sequence of a Staphylococcus aureus strain isolated from the nares of an 18-year-old female healthy persistent-carrier individual, and it was used to investigate S. aureus-specific immune responses in colonized and noncolonized individuals. PMID:29748411

  12. 76 FR 78670 - Draft Guidance for Industry and Food and Drug Administration Staff; Evaluation of Sex Differences...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ...] Draft Guidance for Industry and Food and Drug Administration Staff; Evaluation of Sex Differences in... entitled ``Evaluation of Sex Differences in Medical Device Clinical Studies.'' This document provides guidance on the study and evaluation of sex differences in medical device clinical trials, with a specific...

  13. 78 FR 17708 - Endangered and Threatened Wildlife and Plants; Draft Revised Supplement to the Grizzly Bear...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ...] Endangered and Threatened Wildlife and Plants; Draft Revised Supplement to the Grizzly Bear Recovery Plan... Revised Supplement to the Grizzly Bear Recovery Plan. Specifically, this supplement proposes to revise the demographic recovery criteria for the Yellowstone Ecosystem. In the lower 48 States, Grizzly bears (Ursus...

  14. 77 FR 12853 - Draft Guidances Relating to the Development of Biosimilar Products; Public Hearing; Request for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm. 6340, Silver... the review of 351(k) applications and general scientific principles in conducting comparative analyses... specific, on the scientific considerations, Q&A, and quality considerations draft guidances. For example...

  15. 76 FR 6087 - Draft Weapons Safety Assessment on the Use of Enhanced Weapons; Notice of Availability and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-03

    ... holders, and other stakeholders on a draft guidance document entitled ``Weapons Safety Assessment'' (WSA... weapons under the NRC's proposed rule titled ``Enhanced Weapons, Firearms Background Checks, and Security.... You should not include any site-specific security information in your comments. Federal rulemaking Web...

  16. 77 FR 7586 - Draft Guidance for Industry on Bioequivalence Recommendation for Nitroglycerin Metered Spray...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... though we have not requested comparative in vitro studies, in vitro studies outlined in the 2002 guidance.... The recommendations provide specific guidance on the design of bioequivalence (BE) studies to support... draft guidance for industry on the Agency's recommendations for BE studies to support ANDAs for...

  17. 78 FR 66745 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm. 2201, Silver Spring, MD...], Center for Drug Evaluation and Research (HFD-600), Food and Drug Administration, 7520 Standish Pl... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2007-D-0369...

  18. 78 FR 37230 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm. 2201, Silver Spring, MD...], Center for Drug Evaluation and Research (HFD-600), Food and Drug Administration, 7519 Standish Pl... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2007-D-0369...

  19. 77 FR 10536 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm. 2201, Silver..., Center for Drug Evaluation and Research (HFD-600), Food and Drug Administration, 7519 Standish Pl... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2007-D-0369...

  20. 77 FR 74669 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm. 2201, Silver Spring, MD...], Center for Drug Evaluation and Research (HFD-600), Food and Drug Administration, 7519 Standish Pl... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2007-D-0369...

  1. 75 FR 55797 - Draft Guidance for Industry on Chronic Hepatitis C Virus Infection: Developing Direct-Acting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-14

    ...] Draft Guidance for Industry on Chronic Hepatitis C Virus Infection: Developing Direct-Acting Antiviral... entitled ``Chronic Hepatitis C Virus Infection: Developing Direct-Acting Antiviral Agents for Treatment... antiviral agents (DAAs), defined as agents that interfere with specific steps in the hepatitis C virus (HCV...

  2. 78 FR 10620 - Draft Environmental Assessment and Preliminary Finding of No Significant Impact Concerning a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-14

    ... Engineered Atlantic Salmon; Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION... genetically engineered (GE) Atlantic salmon and a preliminary finding of no significant impact (FONSI) for... salmon and a preliminary FONSI for those specific conditions of use. Comments on the draft EA and FONSI...

  3. Draft Genome Sequence of Lactobacillus johnsonii Strain 16, Isolated from Mice.

    PubMed

    Buhnik-Rosenblau, Keren; Danin-Poleg, Yael; Elgavish, Sharona; Kashi, Yechezkel

    2015-10-08

    Here, we report the genome sequence of Lactobacillus johnsonii, a member of the gut lactobacilli. This draft genome of L. johnsonii strain 16 isolated from C57BL/6J mice enables the identification of bacterial genes responsible for host-specific gut persistence. Copyright © 2015 Buhnik-Rosenblau et al.

  4. 75 FR 6070 - Notice of Public Meeting on the International Atomic Energy Agency Basic Safety Standards Version...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-05

    ... Energy Agency Basic Safety Standards Version 3.0, Draft Safety Requirements DS379 AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Public Meeting on the International Atomic Energy Agency Basic... development of U.S. Government comments on this International Atomic Energy Agency (IAEA) draft General Safety...

  5. National Occupational Skill Standards. CADD: Computer Aided Drafting and Design.

    ERIC Educational Resources Information Center

    National Coalition for Advanced Manufacturing, Washington, DC.

    This document identifies computer-aided drafting and design (CADD) skills that companies require of training programs and future employees. The information was developed by two committees of technically knowledgeable CADD users from across the United States and validated by several hundred other CADD users. The skills are aimed at a beginner CADD…

  6. 75 FR 29350 - Draft Guidance for Industry: Questions and Answers Regarding the Reportable Food Registry as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ...] Draft Guidance for Industry: Questions and Answers Regarding the Reportable Food Registry as Established.... The agency is also seeking comments from industry on the Reportable Food Registry requirements, and... the implementation of the Reportable Food Registry on September 8, 2009, and informs industry about...

  7. 76 FR 5102 - Draft NUREG-0561, Revision 2; Physical Protection of Shipments of Irradiated Reactor Fuel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... 3150-AI64 [NRC-2010-0340] Draft NUREG-0561, Revision 2; Physical Protection of Shipments of Irradiated...-0561, ``Physical Protection of Shipments of Irradiated Reactor Fuel.'' This document provides guidance on implementing the provisions of proposed 10 CFR Part 73.37, ``Requirements for Physical Protection...

  8. 76 FR 82303 - Draft Guidance for Industry on Responding to Unsolicited Requests for Off-Label Information About...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... indication and risk information, post-marketing submission requirements) in their internet and social media... requests for off-label information, including those that firms may encounter on emerging electronic media...] Draft Guidance for Industry on Responding to Unsolicited Requests for Off-Label Information About...

  9. 78 FR 11204 - Accreditation and Reaccreditation Process for Firms Under the Third Party Review Program: Part I...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ...] Accreditation and Reaccreditation Process for Firms Under the Third Party Review Program: Part I; Draft Guidance... announcing the availability of the draft guidance entitled ``Accreditation and Reaccreditation Process for... Act), as amended by the Food and Drug Administration Safety and Innovation Act (FDASIA), requires FDA...

  10. 75 FR 30395 - Stakeholder Input; National Pollutant Discharge Elimination System (NPDES) Permit Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-01

    ..., 2005 draft Peak Flows Policy. This draft Policy attempted to clarify EPA's interpretation that the... treatment plants that are recombined with the flows from the secondary treatment units prior to discharge... peak flow as part of an SSO rulemaking to allow for a holistic and integrated approach to reducing SSOs...

  11. 78 FR 27115 - Draft Guidance for Industry on Expanded Access to Investigational Drugs for Treatment Use...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... a more transparent process by increasing awareness and knowledge of expanded access programs and the... regulations. Consistent with the goal of making expanded access processes more transparent, FDA is providing... (IRB) review and approval required for individual patient expanded access?'' In the draft guidance, FDA...

  12. 75 FR 63189 - Draft Guidance for Industry on Investigational New Drug Applications-Determining Whether Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... obtain approval from the Office of Management and Budget (OMB) for each collection of information they... information before submitting the collection to OMB for approval. To comply with this requirement, FDA is... VIII of the draft guidance, ``Process for Addressing Inquiries Concerning the Application of the IND...

  13. A Draft Protocol for Detecting Possible Biohazards in Martian Samples Returned to Earth

    NASA Technical Reports Server (NTRS)

    Viso, M.; DeVincenzi, D. L.; Race, M. S.; Schad, P. J.; Stabekis, P. D.; Acevedo, S. E.; Rummel, J. D.

    2002-01-01

    In preparation for missions to Mars that will involve the return of samples, it is necessary to prepare for the safe receiving, handling, testing, distributing, and archiving of martian materials here on Earth. Previous groups and committees have studied selected aspects of sample return activities, but a specific protocol for handling and testing of returned -=1 samples from Mars remained to be developed. To refine the requirements for Mars sample hazard testing and to develop criteria for the subsequent release of sample materials from precautionary containment, NASA Planetary Protection Officer, working in collaboration with CNES, convened a series of workshops to produce a Protocol by which returned martian sample materials could be assessed for biological hazards and examined for evidence of life (extant or extinct), while safeguarding the samples from possible terrestrial contamination. The Draft Protocol was then reviewed by an Oversight and Review Committee formed specifically for that purpose and composed of senior scientists. In order to preserve the scientific value of returned martian samples under safe conditions, while avoiding false indications of life within the samples, the Sample Receiving Facility (SRF) is required to allow handling and processing of the Mars samples to prevent their terrestrial contamination while maintaining strict biological containment. It is anticipated that samples will be able to be shipped among appropriate containment facilities wherever necessary, under procedures developed in cooperation with international appropriate institutions. The SRF will need to provide different types of laboratory environments for carrying out, beyond sample description and curation, the various aspects of the protocol: Physical/Chemical analysis, Life Detection testing, and Biohazard testing. The main principle of these tests will be described and the criteria for release will be discussed, as well as the requirements for the SRF and its personnel.

  14. What is the Value of a National Football League Draft Pick? An Analysis Based on Changes Made in the Collective Bargaining Agreement.

    PubMed

    Kraeutler, Matthew J; Carver, Trevor J; Belk, John W; McCarty, Eric C

    2018-06-01

    Kraeutler, MJ, Carver, TJ, Belk, JW, and McCarty, EC. What is the value of a National Football League draft pick? An analysis based on changes made in the collective bargaining agreement. J Strength Cond Res 32(6): 1656-1661, 2018-The purpose of this study was to analyze and compare the value of players drafted in early rounds of the National Football League (NFL) Draft since the new collective bargaining agreement began in 2011. The NFL's player statistics database and database of player contract details were searched for players drafted in the first 3 rounds of the 2011 to 2013 NFL Drafts. Performance outcomes specific to each position were divided by each player's salary to calculate a value statistic. Various demographics, NFL Combine results, and total number of games missed because of injury were also recorded for each player. These statistics were compared within each position between players selected in the first round of the NFL Draft (group A) vs. those drafted in the second or third round (group B). A total of 147 players were included (group A 35, group B 112). Overall, players in group A were significantly taller (p ≤ 0.01) and heavier (p = 0.037) than players in group B. Group B demonstrated significantly greater value statistics than group A for quarterbacks (p = 0.028), wide receivers (p ≤ 0.001), defensive tackles (p = 0.019), and cornerbacks (p ≤ 0.001). No significant differences were found between groups with regard to number of games missed because of injury. Players drafted in the second or third rounds of the NFL Draft often carry more value than those drafted in the first round. NFL teams may wish to more frequently trade down in the Draft rather than trading up.

  15. Reviewers required major changes, including rearranging the two articles, so the new title of the first paper is: HVAC and Refrigeration Experiments at Wal-Mart Experimental Supercenters in Texas and Colorado --- original title: ASHRAE Journal DRAFT article McKinney and Aurora Wal-Mart Stores, Part 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MacDonald, J Michael; Deru, Michael

    2007-01-01

    In 2005, Wal-Mart opened experimental stores in McKinney, Texas (hot climate), and Aurora, Colo. (cold climate). With these projects Wal-Mart can: * Learn how to achieve sustainability improvements; * Gain experience with the design, design process, and operations for some specific advanced technologies; * Understand energy use patterns in their stores more clearly; * Lay groundwork for better understanding of how to achieve major carbon footprint reductions; and * Measure the potential benefits of specific technologies tested.

  16. Supervisors' On-Script Feedback Comments on Drafts of Dissertations: Socialising Students into the Academic Discourse Community

    ERIC Educational Resources Information Center

    Basturkmen, Helen; East, Martin; Bitchener, John

    2014-01-01

    Supervising masters and doctoral dissertations is a key function of teaching in higher education and giving written feedback on draft sections is an essential component of this function. However, the specific types of response that supervisors give to their dissertation students' written work have received limited research interest to date. The…

  17. Nanomaterial Case Study: A Comparison of Multiwalled Carbon Nanotube and Decabromodiphenyl Ether Flame-Retardant Coatings Applied to Upholstery Textiles (Independent Peer Review Draft)

    EPA Science Inventory

    This Independent Peer Review Draft document presents a case study of multiwalled carbon nanotubes (MWCNTs); it focuses on the specific example of MWCNTs as used in flame-retardant coatings applied to upholstery textiles. This case study is organized around the comprehensive envir...

  18. 77 FR 12543 - Endangered and Threatened Wildlife and Plants; Revised Critical Habitat for Riverside Fairy Shrimp

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ...; reopening of comment period, notice of availability of draft economic analysis, and amended required... 3(5)(A)(ii) of the Act because these areas are essential for the conservation of the species but.... We also announce the availability of a draft economic analysis (DEA) of the proposed designation of...

  19. 76 FR 38676 - Gulf of Mexico (GOM), Outer Continental Shelf (OCS), Central Planning Area (CPA), Oil and Gas...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... September 2008. SUPPLEMENTARY INFORMATION: BOEMRE developed the Draft SEIS for CPA Lease Sale 216/222 to consider new information made available since completion of the Multisale EIS and 2009-2012 SEIS, including information concerning the Deepwater Horizon event and spill and new regulatory requirements. This Draft SEIS...

  20. 76 FR 14358 - Pesticides; Data Requirements for Plant-Incorporated Protectants (PIPs) and Certain Exemptions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... Exemptions for PIPs; Notification to the Secretaries of Agriculture and Health and Human Services AGENCY... to the Secretaries of Agriculture and Health and Human Services a draft proposed rule under sections... provide the Secretary of Health and Human Services with a copy of any draft proposed rule pertaining to a...

  1. 7 CFR 1794.72 - Adoption of an EIS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Adoption of an EIS. 1794.72 Section 1794.72... Adoption of an EIS. (a) Where RUS determines that an existing Federal EIS requires additional information... portion of the EIS as a part of its draft EIS. The circulation and notice provisions for a draft and final...

  2. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... location of the public libraries where the public can find your materials separation plan. Include the... separation plan available to the public? 60.1070 Section 60.1070 Protection of Environment ENVIRONMENTAL... Preconstruction Requirements: Materials Separation Plan § 60.1070 How do I make my draft materials separation plan...

  3. Another Look at the Draft Mil-Std-1540E Unit Random Vibration Test Requirements

    NASA Astrophysics Data System (ADS)

    Perl, E.; Peterson, A. J..; Davis, D.

    2012-07-01

    The draft Mil-Std-1540E has been updated to reflect lessons learned since its publication as an SMC Standard in 2008, [1], and an earlier Aerospace Corporation Technical Report released in 2006, [2]. This paper discusses the technical rationale supporting some of the unit random vibration test requirements to provide better insight into their derivation and application to programs. It is intended that these requirements be tailored for each program to reflect the customer risk profile. Several tailoring options are provided and a two phase test strategy is discussed to highlight its applicability to utilizing heritage hardware in new applications.

  4. The long-term effects of military conscription on mortality: estimates from the Vietnam-era draft lottery.

    PubMed

    Conley, Dalton; Heerwig, Jennifer

    2012-08-01

    Research on the effects of Vietnam military service suggests that Vietnam veterans experienced significantly higher mortality than the civilian population at large. These results, however, may be biased by nonrandom selection into the military if unobserved background differences between veterans and nonveterans affect mortality directly. To generate unbiased estimates of exposure to conscription on mortality, the present study compares the observed proportion of draft-eligible male decedents born 1950-1952 to the (1) expected proportion of draft-eligible male decedents given Vietnam draft-eligibility cutoffs; and (2) observed proportion of draft-eligible decedent women. The results demonstrate no effect of draft exposure on mortality, including for cause-specific death rates. When we examine population subgroups-including splits by race, educational attainment, nativity, and marital status-we find weak evidence for an interaction between education and draft eligibility. This interaction works in the opposite direction of putative education-enhancing, mortality-reducing effects of conscription that have, in the past, led to concern about a potential exclusion restriction violation in instrumental variable (IV) regression models. We suggest that previous research, which has shown that Vietnam-era veterans experienced significantly higher mortality than nonveterans, might be biased by nonrandom selection into the military and should be further investigated.

  5. The tissue microarray data exchange specification: A community-based, open source tool for sharing tissue microarray data

    PubMed Central

    Berman, Jules J; Edgerton, Mary E; Friedman, Bruce A

    2003-01-01

    Background Tissue Microarrays (TMAs) allow researchers to examine hundreds of small tissue samples on a single glass slide. The information held in a single TMA slide may easily involve Gigabytes of data. To benefit from TMA technology, the scientific community needs an open source TMA data exchange specification that will convey all of the data in a TMA experiment in a format that is understandable to both humans and computers. A data exchange specification for TMAs allows researchers to submit their data to journals and to public data repositories and to share or merge data from different laboratories. In May 2001, the Association of Pathology Informatics (API) hosted the first in a series of four workshops, co-sponsored by the National Cancer Institute, to develop an open, community-supported TMA data exchange specification. Methods A draft tissue microarray data exchange specification was developed through workshop meetings. The first workshop confirmed community support for the effort and urged the creation of an open XML-based specification. This was to evolve in steps with approval for each step coming from the stakeholders in the user community during open workshops. By the fourth workshop, held October, 2002, a set of Common Data Elements (CDEs) was established as well as a basic strategy for organizing TMA data in self-describing XML documents. Results The TMA data exchange specification is a well-formed XML document with four required sections: 1) Header, containing the specification Dublin Core identifiers, 2) Block, describing the paraffin-embedded array of tissues, 3)Slide, describing the glass slides produced from the Block, and 4) Core, containing all data related to the individual tissue samples contained in the array. Eighty CDEs, conforming to the ISO-11179 specification for data elements constitute XML tags used in the TMA data exchange specification. A set of six simple semantic rules describe the complete data exchange specification. Anyone using the data exchange specification can validate their TMA files using a software implementation written in Perl and distributed as a supplemental file with this publication. Conclusion The TMA data exchange specification is now available in a draft form with community-approved Common Data Elements and a community-approved general file format and data structure. The specification can be freely used by the scientific community. Efforts sponsored by the Association for Pathology Informatics to refine the draft TMA data exchange specification are expected to continue for at least two more years. The interested public is invited to participate in these open efforts. Information on future workshops will be posted at (API we site). PMID:12769826

  6. Secure HL7 transactions using Internet mail (Internet draft).

    PubMed

    Schadow, Gunther; Tucker, Mark; Rishel, Wes

    2002-01-01

    The document describes the applicability of the Internet standardisation efforts on secure electronic data interchange (EDI) transactions for Health Level-7 (HL7), an EDI standard for Healthcare used world-wide. The document heavily relies on the work in progress by the IETF EDIINT working group. It is in most parts a restatement of the EDIINTs requirements document and application statement 1 (AS#1) tailored to the needs of the HL7 audience. The authors tried to make the document as self consistent as possible. The goal is to give to the reader who is not a security or Internet standards expert enough foundational and detail information to enable him to build communication software that complies to the Internet standards. Even though the authors rely on and promote the respective Internet standards and drafts, they did not withstand from commenting on and criticising the work where they see upcoming problems in use with HL7 or other EDI protocols that have not been in the initial focus of the EDIINT working group. The authors make suggestions to add parameters to the specification of the MIME type for EDI messages in RFC 1767 in order to enhance functionality. The authors give use cases for a larger subset of disposition types and modifiers of message disposition notifications. One key issue where the document goes beyond the current EDIINT drafts is the concept of non-repudiation of commitment to an EDI transaction. Secure EDI transactions should be regarded as "distributed contracts," i.e. not only the sending and receiving of single messages should be non-refutable but also the connection between messages interchanges. In anticipation of this requirement HL7 usually requires a response message to be sent to acknowledge every transaction. The authors therefore have the requirement to securely couple an EDI response message to its request message. Given the current shape of RFC 1767 this is generally possible only if a response message is coupled with an MDN receipt and the combination of both signed by the responder. The document describes a protocol to bundle MDN and response that uses the MIME multi-part/related content type in RFC 2112.

  7. Nanomaterial Case Study: A Comparison of Multiwalled Carbon Nanotube and Decabromodiphenyl Ether Flame-Retardant Coatings Applied to Upholstery Textiles (External Review Draft)

    EPA Science Inventory

    The draft document is intended to be used as part of a process to identify what is known and, more importantly, what is not yet known that could be of value in assessing the broad implications of specific nanomaterials. Like previous case studies (see History/ Chronology below), ...

  8. Extensive Error in the Number of Genes Inferred from Draft Genome Assemblies

    PubMed Central

    Denton, James F.; Lugo-Martinez, Jose; Tucker, Abraham E.; Schrider, Daniel R.; Warren, Wesley C.; Hahn, Matthew W.

    2014-01-01

    Current sequencing methods produce large amounts of data, but genome assemblies based on these data are often woefully incomplete. These incomplete and error-filled assemblies result in many annotation errors, especially in the number of genes present in a genome. In this paper we investigate the magnitude of the problem, both in terms of total gene number and the number of copies of genes in specific families. To do this, we compare multiple draft assemblies against higher-quality versions of the same genomes, using several new assemblies of the chicken genome based on both traditional and next-generation sequencing technologies, as well as published draft assemblies of chimpanzee. We find that upwards of 40% of all gene families are inferred to have the wrong number of genes in draft assemblies, and that these incorrect assemblies both add and subtract genes. Using simulated genome assemblies of Drosophila melanogaster, we find that the major cause of increased gene numbers in draft genomes is the fragmentation of genes onto multiple individual contigs. Finally, we demonstrate the usefulness of RNA-Seq in improving the gene annotation of draft assemblies, largely by connecting genes that have been fragmented in the assembly process. PMID:25474019

  9. Extensive error in the number of genes inferred from draft genome assemblies.

    PubMed

    Denton, James F; Lugo-Martinez, Jose; Tucker, Abraham E; Schrider, Daniel R; Warren, Wesley C; Hahn, Matthew W

    2014-12-01

    Current sequencing methods produce large amounts of data, but genome assemblies based on these data are often woefully incomplete. These incomplete and error-filled assemblies result in many annotation errors, especially in the number of genes present in a genome. In this paper we investigate the magnitude of the problem, both in terms of total gene number and the number of copies of genes in specific families. To do this, we compare multiple draft assemblies against higher-quality versions of the same genomes, using several new assemblies of the chicken genome based on both traditional and next-generation sequencing technologies, as well as published draft assemblies of chimpanzee. We find that upwards of 40% of all gene families are inferred to have the wrong number of genes in draft assemblies, and that these incorrect assemblies both add and subtract genes. Using simulated genome assemblies of Drosophila melanogaster, we find that the major cause of increased gene numbers in draft genomes is the fragmentation of genes onto multiple individual contigs. Finally, we demonstrate the usefulness of RNA-Seq in improving the gene annotation of draft assemblies, largely by connecting genes that have been fragmented in the assembly process.

  10. 76 FR 57751 - Notice of Availability of a Draft Programmatic Environmental Impact Statement for Northern Border...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... particular place. Because this effort is programmatic in nature, the Draft PEIS does not define effects for a... the purposes of the PEIS, the Northern Border is defined as the area between the United States and... environmental quality and the government's role in protecting it. The essence of NEPA is the requirement that...

  11. 77 FR 2999 - Notice of Availability of the Draft Environmental Impact Statement and Notice of Segregation for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-20

    ... Resource Management Plan. The proposed wind turbines would be up to 262-feet-tall from the ground to the... to 415 feet. In addition to the wind turbines, the proposed project would require the construction of... the Draft EIS--an 87 wind turbine layout, a 96 wind turbine alternative, and a no-action alternative...

  12. Air Quality Criteria for Particulate Matter (Fourth External Review Draft) [revised Drafts of Chapters 7 and 8, December 2003

    EPA Science Inventory

    EPA is in the process of updating and revising, where appropriate, its Air Quality Criteria for Particulate Matter as issued in 1996 (usually referred to as the Criteria Document). Sections 108 and 109 of the Clean Air Act require that EPA carry out a periodic review an...

  13. Lumbar Spine Injury/Pathology as a Predictor of Outcomes in National Football League Athletes

    PubMed Central

    Lynch, Thomas Sean; Schroeder, Greg; Gibbs, Daniel; Chow, Ian; LaBelle, Mark; Savage, Jason W.; Patel, Alpesh; Hsu, Wellington; Nuber, Gordon W.

    2014-01-01

    Objectives: The purpose of this study is to determine if a pre-existing lumbar diagnosis such as spondylosis, a herniated lumbar disc, or spondylolysis affects a football player’s draft status or his performance and longevity in the NFL. Methods: The written medical evaluations and imaging reports of prospective professional American football athletes from 2003-2011 from one NFL franchise during the NFL combine (annual college football player evaluation prior to the NFL draft) were compiled and evaluated. All players were evaluated for a pre-existing lumbar diagnosis which were compiled from previous injury/medical records including radiographic imaging reports. Those players with a lumbar spine diagnosis and with appropriate radiograph, MRI and CT imaging were included in this study. These athletes were then matched by age, position, year, and round drafted to control draftees without a lumbar spine diagnosis. Career statistics were compiled including length of play and number of games started. Additionally, a previously established “Performance Score” was calculated for all players excluding offensive linemen. The continuous variables of each cohort were compared using a two-sided (tailed) Student’s t-test for normally distributed data. A chi-squared analysis was performed to analyze the categorical data. Statistical significance was accepted with a p < 0.05. Results: Out of a total of 2,965 athletes evaluated from the NFL combine, 414 players were identified with a pre-existing lumbar spine diagnosis. Athletes who attended the NFL combine without a lumbar spine diagnosis were significantly more likely to be drafted than those with one (74% vs. 61% respectively, p < 0.01). There was no difference between the investigational and control group with regard to round drafted, age, year drafted, or position. Overall, athletes with a lumbar spine injury compared to the control group had no difference in the number of years played (4.0 vs. 4.3 years, respectively, p = 0.13), games played (46.5 vs. 50.7, respectively, p = 0.15), games started (28.1 vs. 30.6, respectively, p = 0.39) or performance score (1.4 vs. 1.8, respectively, p = 0.3) (Figure 1). Conclusion: The data in this study suggests that a pre-existing lumbar spine diagnosis was associated with a significantly lower draft status for NFL athletes. However, the data in our study suggests that such a diagnosis did not affect a player’s career longevity or performance. Further study will be required to determine the individual effects of specific conditions on performance.

  14. [Draft of Guidelines for Human Body Dissection for Clinical Anatomy Education and Research and commentary].

    PubMed

    Shichinohe, Toshiaki; Kondo, Satoshi; Ide, Chizuka; Higuchi, Norio; Aiso, Sadakazu; Sakai, Tatsuo; Matsumura, George; Yoshida, Kazunari; Kobayashi, Eiji; Tatsumi, Haruyuki; Yaginuma, Hiroyuki; Hishikawa, Shuji; Sugimoto, Maki; Izawa, Yoshimitsu; Imanishi, Nobuaki

    2011-07-01

    This article analyses the Draft of Guidelines for Human Body Dissection for Clinical Anatomy Education and Research drawn by the Study Group for Future Training Systems of Surgical Skills and Procedures established by the Fiscal Year 2010 research program of the Ministry of Health, Labor and Welfare. The purpose of the Draft of Guidelines is: First, to lay out the required basic guidelines for human cadaver usage to allow medical and dental faculty to conduct clinical education and research in accordance with existing regulations. Second, the guidelines are expected to give physicians a regulatory framework to carry out cadaver training in accordance with the current legal framework. This article explains the Draft of Guidelines in detail, outlines the future of cadaver training, and describes issues which must still be solved.

  15. [Draft of guidelines for human body dissection for clinical anatomy education and research and commentary].

    PubMed

    Shichinohe, Toshiaki; Kondo, Satoshi; Ide, Chizuka; Higuchi, Norio; Aiso, Sadakazu; Sakai, Tatsuo; Matsumura, George; Yoshida, Kazunari; Kobayashi, Eiji; Tatsumi, Haruyuki; Yaginuma, Hiroyuki; Hishikawa, Shuji; Sugimoto, Maki; Izawa, Yoshimitsu; Imanishi, Nobuaki

    2011-06-01

    This article analyses the Draft of Guidelines for Human Body Dissection for Clinical Anatomy Education and Research drawn by the Study Group for Future Training Systems of Surgical Skills and Procedures established by the Fiscal Year 2010 research program of the Ministry of Health, Labor and Welfare. The purpose of the Draft of Guidelines is: First, to lay out the required basic guidelines for human cadaver usage to allow medical and dental faculty to conduct clinical education and research in accordance with existing regulations. Second, the guidelines are expected to give physicians a regulatory framework to carry out cadaver training in accordance with the current legal framework. This article explains the Draft of Guidelines in detail, outlines the future of cadaver training, and describes issues which must still be solved.

  16. 46 CFR 169.840 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... that the vessel complies with all applicable stability requirements in the vessel's trim and stability... stability requirements the vessel's draft, trim, and stability must be determined as necessary and any...

  17. 46 CFR 196.15-7 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the vessel complies with all applicable stability requirements in the vessel's trim and stability book... requirements the vessel's draft, trim, and stability must be determined as necessary and any stability...

  18. 46 CFR 167.65-42 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... that the vessel complies with all applicable stability requirements in the vessel's trim and stability... stability requirements the vessel's draft, trim, and stability must be determined as necessary and any...

  19. 46 CFR 169.840 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... that the vessel complies with all applicable stability requirements in the vessel's trim and stability... stability requirements the vessel's draft, trim, and stability must be determined as necessary and any...

  20. 46 CFR 167.65-42 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... that the vessel complies with all applicable stability requirements in the vessel's trim and stability... stability requirements the vessel's draft, trim, and stability must be determined as necessary and any...

  1. 46 CFR 196.15-7 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the vessel complies with all applicable stability requirements in the vessel's trim and stability book... requirements the vessel's draft, trim, and stability must be determined as necessary and any stability...

  2. Environmental Assessment for Construction of Radial Arm Spill Gates MacDill Air Force Base, Florida

    DTIC Science & Technology

    2012-05-01

    requires that Federal agencies identify and assess environmental health and safety risks that might disproportionately affect children. The Proposed...Action would not pose any adverse or disproportionate environmental health or safety risks to children living near the base. Safety precautions...Department of Envir. Protection 3900 Commonwealth Blvd, Mail Station 47 Tallahassee, FL 32399-3000 RE: Draft Environmental Assessment and Draft

  3. High-Quality Draft Genome Sequence of Thermocrinis jamiesonii GBS1 T Isolated from Great Boiling Spring, Nevada

    DOE PAGES

    Ganji, Rakesh; Murugapiran, Senthil K.; Ong, John C.; ...

    2016-10-20

    The draft genome of Thermocrinis jamiesonii GBS1 T is 1,315,625 bp in 10 contigs and encodes 1,463 predicted genes. The presence of sox genes and various glycoside hydrolases and the absence of uptake NiFe hydrogenases ( hyaB) are consistent with a requirement for thiosulfate and suggest the ability to use carbohydrate polymers.

  4. Habitat types of the Tenderfoot Creek Experimental Forest

    Treesearch

    David M. Ondov

    1975-01-01

    In May 1974, a review draft of the Forest Habitat Types of Montana (Pfister et al. 1974) was released for use by Forest Service personnel and others requiring a method of ecosystem classification as a means to stratify forest environments in Montana. With the use of this review draft in mind, an objective was outlined to develop a vegetation map of the Tenderfoot Creek...

  5. Fall Department Head Report--Reporting Booklet 2.0 to the Massachusetts Division of Occupational Education (Fiscal Year Ending June 30, 1975) for Drafting.

    ERIC Educational Resources Information Center

    Management and Information System for Occupational Education, Winchester, MA.

    The reporting booklet is required for the Census Data System (CDS) of the Management Information System for Occupational Education (MISOE); it contains the reporting forms which collect data that describe program structure and job-entry skill outcomes expected of program completors in the individual occupational education area of drafting.…

  6. 75 FR 78798 - Airport Improvement Program: Proposed Changes to Benefit Cost Analysis (BCA) Threshold

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-16

    ...The Federal Aviation Administration (FAA) is issuing this Notice to advise that FAA has developed draft guidance modifying its policy requiring benefit cost analyses (BCA) for capacity projects when applying for Airport Improvement Program (AIP) grants for capacity projects at the discretion of the Secretary of Transportation. This modification proposes to raise the threshold at which BCAs are required, from $5 million to $10 million in AIP Discretionary funds. FAA invites airport sponsors and other interested parties to comment on the draft guidance. FAA will consider these comments in promulgating final BCA guidance for airport sponsors.

  7. Draft New Home Specification Version 1.1

    EPA Pesticide Factsheets

    The intent of this specification is to reduce indoor and outdoor water usage in new residential homes, thereby lowering consumer utility bills and encouraging water and wastewater.infrastructure savings.

  8. 46 CFR 97.15-7 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... applicable stability requirements in the vessel's trim and stability book, stability letter, Certificate of... the vessel's draft, trim, and stability must be determined as necessary. (c) If a log book is required...

  9. 46 CFR 97.15-7 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... applicable stability requirements in the vessel's trim and stability book, stability letter, Certificate of... the vessel's draft, trim, and stability must be determined as necessary. (c) If a log book is required...

  10. Storage requirements for Georgia streams

    USGS Publications Warehouse

    Carter, Robert F.

    1983-01-01

    The suitability of a stream as a source of water supply or for waste disposal may be severely limited by low flow during certain periods. A water user may be forced to provide storage facilities to supplement the natural flow if the low flow is insufficient for his needs. This report provides data for evaluating the feasibility of augmenting low streamflow by means of storage facilities. It contains tabular data on storage requirements for draft rates that are as much as 60 percent of the mean annual flow at 99 continuous-record gaging stations, and draft-storage diagrams for estimating storage requirements at many additional sites. Through analyses of streamflow data, the State was divided into four regions. Draft-storage diagrams for each region provide a means of estimating storage requirements for sites on streams where data are scant, provided the drainage area, mean annual flow, and the 7-day, 10-year low flow are known or can be estimated. These data are tabulated for the 99 gaging stations used in the analyses and for 102 partial-record sites where only base-flow measurements have been made. The draft-storage diagrams are useful not only for estimating in-channel storage required for low-flow augmentation, but also can be used for estimating the volume of off-channel storage required to retain wastewater during low-flow periods for later release. In addition, these relationships can be helpful in estimating the volume of wastewater to be disposed of by spraying on land, provided that the water disposed of in this manner is only that for which streamflow dilution water is not currently available. Mean annual flow can be determined for any stream within the State by using the runoff map in this report. Low-flow indices can be estimated by several methods, including correlation of base-flow measurements with concurrent flow at nearby continuous-record gaging stations where low-flow indices have been determined.

  11. The draft genome sequence of Mangrovibacter sp. strain MP23, an endophyte isolated from the roots of Phragmites karka.

    PubMed

    Behera, Pratiksha; Vaishampayan, Parag; Singh, Nitin K; Mishra, Samir R; Raina, Vishakha; Suar, Mrutyunjay; Pattnaik, Ajit K; Rastogi, Gurdeep

    2016-09-01

    Till date, only one draft genome has been reported within the genus Mangrovibacter. Here, we report the second draft genome shotgun sequence of a Mangrovibacter sp. strain MP23 that was isolated from the roots of Phargmites karka (P. karka), an invasive weed growing in the Chilika Lagoon, Odisha, India. Strain MP23 is a facultative anaerobic, nitrogen-fixing endophytic bacteria that grows optimally at 37 °C, 7.0 pH, and 1% NaCl concentration. The draft genome sequence of strain MP23 contains 4,947,475 bp with an estimated G + C content of 49.9% and total 4392 protein coding genes. The genome sequence has provided information on putative genes that code for proteins involved in oxidative stress, uptake of nutrients, and nitrogen fixation that might offer niche specific ecological fitness and explain the invasive success of P. karka in Chilika Lagoon. The draft genome sequence and annotation have been deposited at DDBJ/EMBL/GenBank under the accession number LYRP00000000.

  12. EXTERNAL PEER REVIEW OF THE DRAFT REGION 4 ...

    EPA Pesticide Factsheets

    EPA scientists in Region 4 (Atlanta) conducted a review of data and information regarding hypoxia in the northern Gulf of Mexico. This Region 4 staff assessment concluded that phosphorus, rather than nitrogen, may be the limiting nutrient controlling Gulf hypoxia. An unauthorized draft of the report was released in January of 2004. This report, because of its controversial conclusion regarding the role of phosphorus in Gulf hypoxia, caused a significant amount of concern among stakeholders. After considerable internal review by Region 4 EPA scientists, the Region released a significantly revised version of the draft report for a broader internal EPA review in April 2004. The report was revised based on the broader EPA review and released to the Hypoxia Task Force in August 2004, as an informational document with the specific purpose of encouraging discussion and posing questions for the reassessment of the Action Plan. The draft report,

  13. The New US Preventive Services Task Force "C" Draft Recommendation for Prostate Cancer Screening.

    PubMed

    Cooperberg, Matthew R

    2017-09-01

    The US Preventive Services Task Force has issued a new draft guideline, with a "C" recommendation that men aged 55-69 yr should be informed about the benefits and harms of screening for prostate cancer, and offered prostate-specific antigen testing if they choose it. For men aged ≥70 yr, the recommendation remains "D", or "do not screen." This draft represents substantial progress in the right direction towards offering men a fair opportunity to discuss the risks and benefits of screening with their primary care providers. However, the evidence review underlying the draft remains fundamentally inadequate, leading to biased presentations of both benefits and harms of screening. The final guideline and future revisions should reflect formal engagement with subject matter experts to optimize the advise given to men and their physicians. Copyright © 2017 European Association of Urology. Published by Elsevier B.V. All rights reserved.

  14. FORENSIC DNA BANKING LEGISLATION IN DEVELOPING COUNTRIES: PRIVACY AND CONFIDENTIALITY CONCERNS REGARDING A DRAFT FROM TURKISH LEGISLATION.

    PubMed

    Ilgili, Önder; Arda, Berna

    This paper presents and analyses, in terms of privacy and confidentiality, the Turkish Draft Law on National DNA Database prepared in 2004, and concerning the use of DNA analysis for forensic objectives and identity verification in Turkey. After a short introduction including related concepts, we evaluate the draft law and provide articles about confidentiality. The evaluation reminded us of some important topics at international level for the developing countries. As a result, the need for sophisticated legislations about DNA databases, for solutions to issues related to the education of employees, and the technological dependency to other countries emerged as main challenges in terms of confidentiality for the developing countries. As seen in the Turkish Draft Law on National DNA Database, the protection of the fundamental rights and freedoms requires more care during the legislative efforts.

  15. Cargo Movement Operations System (CMOS) Interface Requirements Specification (Draft). Increment II

    DTIC Science & Technology

    1990-05-17

    NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [ 3 CLOSED [ ] ORIGINATOR CONTROL NUMBER: IRS1-0003 PROGRAM OFFICE CONTROL NUMBER: DATA ITEM DISCREPANCY WORKSHEET CDRL NUMBER: A004-05 DATE: 05/17/90 ORIGINATOR NAME: Ronald J. Lacour OFFICE SYMBOL: SAIC TELEPHONE NUMBER: 272-2999 SUBSTANTIVE: X EDITORIAL: PAGE NUMBER: 9 PARA NUMBER: 3.2 c. COMMENT OR RECOMMENDED CHANGE: Change line 2 to read, "CMOS IRD/SBSS-01 and SBSS-03." Move "CMOS IRD/SBSS-02" to paragraph 3.3 c. RATIONALE: The CMOS IRD/SBSS-02 covers the Shipment Suspense

  16. Cargo Movement Operations System (CMOS). Interface Requirements Specification. Revised Draft. Increment 2

    DTIC Science & Technology

    1990-08-02

    NO [ ] COMMENT DISPOSITION: ACCEPT [ ] REJECT [ ] COMMENT STATUS: OPEN [ ] CLOSED [ ] Cmnt Page Paragraph No. No. Number Comment ------------ ---- --------- -------------------------------------------- 1. 12 Table 3.1.2 Add "(On-Base)" to CC0205 - ADAM III to CMOS. 2. 28 3.10.2 c. Add reference to Table 3.11.21. 3. 30 3.12.1 b.(2) Change "Conformation of Listed Manifest" to "Confirmation of Lifted Manifest". 4. 50 3.34 d. Change this paragraph ref 2rence to 3.33 d. 5. 58 Table 6.3 Change the second "CMOS to ADAM III

  17. Transnational Threats: Blending Law Enforcement and Military Strategies

    DTIC Science & Technology

    2000-11-01

    Providing Humanitarian Assistance Following NBC Accidents/Incidents: The Legal Considerations, Colorado Springs, CO: Institute for National Security Studies...draft of a position on cyber crime .36 The draft focused on such issues as extradition, mutual legal assistance, and trans-border computer searches. These...warfare also raises specific legal issues related to computer crime : what is a crime , who commits it, and what does the law say about it? 21. A

  18. Findings from a novel approach to publication guideline revision: user road testing of a draft version of SQUIRE 2.0

    PubMed Central

    Davies, Louise; Donnelly, Kyla Z; Goodman, Daisy J; Ogrinc, Greg

    2016-01-01

    Background The Standards for Quality Improvement Reporting Excellence (SQUIRE) Guideline was published in 2008 (SQUIRE 1.0) and was the first publication guideline specifically designed to advance the science of healthcare improvement. Advances in the discipline of improvement prompted us to revise it. We adopted a novel approach to the revision by asking end-users to ‘road test’ a draft version of SQUIRE 2.0. The aim was to determine whether they understood and implemented the guidelines as intended by the developers. Methods Forty-four participants were assigned a manuscript section (ie, introduction, methods, results, discussion) and asked to use the draft Guidelines to guide their writing process. They indicated the text that corresponded to each SQUIRE item used and submitted it along with a confidential survey. The survey examined usability of the Guidelines using Likert-scaled questions and participants’ interpretation of key concepts in SQUIRE using open-ended questions. On the submitted text, we evaluated concordance between participants’ item usage/interpretation and the developers’ intended application. For the survey, the Likert-scaled responses were summarised using descriptive statistics and the open-ended questions were analysed by content analysis. Results Consistent with the SQUIRE Guidelines’ recommendation that not every item be included, less than one-third (n=14) of participants applied every item in their section in full. Of the 85 instances when an item was partially used or was omitted, only 7 (8.2%) of these instances were due to participants not understanding the item. Usage of Guideline items was highest for items most similar to standard scientific reporting (ie, ‘Specific aim of the improvement’ (introduction), ‘Description of the improvement’ (methods) and ‘Implications for further studies’ (discussion)) and lowest (<20% of the time) for those unique to healthcare improvement (ie, ‘Assessment methods for context factors that contributed to success or failure’ and ‘Costs and strategic trade-offs’). Items unique to healthcare improvement, specifically ‘Evolution of the improvement’, ‘Context elements that influenced the improvement’, ‘The logic on which the improvement was based’, ‘Process and outcome measures’, demonstrated poor concordance between participants’ interpretation and developers’ intended application. Conclusions User testing of a draft version of SQUIRE 2.0 revealed which items have poor concordance between developer intent and author usage, which will inform final editing of the Guideline and development of supporting supplementary materials. It also identified the items that require special attention when teaching about scholarly writing in healthcare improvement. PMID:26263916

  19. Health impact assessment as an agent of policy change: improving the health impacts of the mayor of London's draft transport strategy.

    PubMed

    Mindell, J; Sheridan, L; Joffe, M; Samson-Barry, H; Atkinson, S

    2004-03-01

    To increase the positive and mitigate the negative health impacts of the mayor's draft transport strategy for London. A rapid prospective health impact assessment (HIA) of the penultimate draft of the strategy, using a review commissioned by the regional director of public health; an appraisal of congestion charging; and a participatory workshop. Two audits of changes were performed to assess the impact on policy of the HIA process. Regional government policy development. Recommendations from the rapid HIA were fed back into the drafting process. Changes (a) between the penultimate draft and the draft for public consultation and (b) between that and the final mayoral strategy. The draft transport strategy published for consultation differed in a number of respects from the previous version. Almost all the recommendations from the HIA were incorporated into the final strategy. Significant changes included promoting sustainable travel plans for workplaces and schools; giving priority to infrastructure and services that benefit London's deprived communities; increased emphasis on promoting walking and cycling and reducing reliance on private cars; and a commitment to track the health impacts of the final strategy and its implementation. Specific additions included re-allocating road space. HIA was successful in influencing the transport strategy for London, resulting in several improvements from a health viewpoint. HIA is an effective method both for bringing about significant change in policy proposals and in increasing policy makers' understanding of determinants of health and hence in changing attitudes of policy makers.

  20. 46 CFR 131.513 - Verification of compliance with applicable stability requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... its trim-and-stability book, stability letter, Certificate of Inspection, and Loadline Certificate... stability requirements, the master shall ascertain the vessel's draft, trim, and stability as necessary; and...

  1. 46 CFR 131.513 - Verification of compliance with applicable stability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... its trim-and-stability book, stability letter, Certificate of Inspection, and Loadline Certificate... stability requirements, the master shall ascertain the vessel's draft, trim, and stability as necessary; and...

  2. A review of the FDA draft guidance document for software validation: guidance for industry.

    PubMed

    Keatley, K L

    1999-01-01

    A Draft Guidance Document (Version 1.1) was issued by the United States Food and Drug Administration (FDA) to address the software validation requirement of the Quality System Regulation, 21 CFR Part 820, effective June 1, 1997. The guidance document outlines validation considerations that the FDA regards as applicable to both medical device software and software used to "design, develop or manufacture" medical devices. The Draft Guidance is available at the FDA web site http:@www.fda.gov/cdrh/comps/swareval++ +.html. Presented here is a review of the main features of the FDA document for Quality System Regulation (QSR), and some guidance for its implementation in industry.

  3. 77 FR 51811 - Draft Guidance for Industry on Self-Identification of Generic Drug Facilities, Sites, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ... as it prepares to meet the self- identification requirement. It explains who is required to self... describing how FDA will implement the self- identification requirement contained in GDUFA. As required by... industry as it prepares to meet the self-identification requirement. The guidance explains who is required...

  4. AEDT Software Requirements Documents - Draft

    DOT National Transportation Integrated Search

    2007-01-25

    This software requirements document serves as the basis for designing and testing the Aviation Environmental Design Tool (AEDT) software. The intended audience for this document consists of the following groups: the AEDT designers, developers, and te...

  5. The UK's Draft Guidance for Health in SEA in light of HIA community priorities and the UNECE SEA Protocol

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Posas, Paula J., E-mail: pjposas@gmail.co

    2011-04-15

    The Protocol on Strategic Environmental Assessment (SEA) to the United Nations Economic Commission for Europe (UNECE) Espoo Convention came into force on 11 July 2010. This Protocol, to which the European Union is party, gives a legal basis for enhanced attention to human health in the SEA process. In this context, the United Kingdom's (UK's) 2007 Draft Guidance on Health in Strategic Environmental Assessment represents an important early government-led effort to bring health issues and public health considerations more significantly into the SEA process. Since the UK is a worldwide leader in environmental and various other types of impact assessment,more » and since other countries may eventually consider its example in efforts to meet UNECE SEA Protocol requirements, scrutiny of its outputs is warranted. This paper thus examines the UK's Draft Guidance from both HIA academic and practitioner perspectives. First it assesses the extent to which the Draft Guidance reflects recent issues and lessons learned in the academic literature. In order to make the assessment, a meta-analysis of 70 HIA-related peer-reviewed articles was undertaken to extract authors' priority recommendations. These recommendations were subsequently compared with the contents of the Draft Guidance. Secondly, the Draft Guidance was assessed for its accordance with recommendations of the UNECE SEA Protocol background paper written by two HIA practitioners. Overall, the Draft Guidance's accordance with both sets of recommendations was found to be high, with only a few easily-remedied gaps. This evaluation suggests that the UK's Draft Guidance can be a useful starting point in the creation of future guidance on health in SEA in both the UK and other countries.« less

  6. Maximising performance in triathlon: applied physiological and nutritional aspects of elite and non-elite competitions.

    PubMed

    Bentley, David J; Cox, Gregory R; Green, Daniel; Laursen, Paul B

    2008-07-01

    Triathlon is a sport consisting of sequential swimming, cycling and running. The main diversity within the sport of triathlon resides in the varying event distances, which creates specific technical, physiological and nutritional considerations for athlete and practitioner alike. The purpose of this article is to review physiological as well as nutritional aspects of triathlon and to make recommendations on ways to enhance performance. Aside from progressive conditioning and training, areas that have shown potential to improve triathlon performance include drafting when possible during both the swim and cycle phase, wearing a wetsuit, and selecting a lower cadence (60-80 rpm) in the final stages of the cycle phase. Adoption of a more even racing pace during cycling may optimise cycling performance and induce a "metabolic reserve" necessary for elevated running performance in longer distance triathlon events. In contrast, drafting in swimming and cycling may result a better tactical approach to increase overall performance in elite Olympic distance triathlons. Daily energy intake should be modified to reflect daily training demands to assist triathletes in achieving body weight and body composition targets. Carbohydrate loading strategies and within exercise carbohydrate intake should reflect the specific requirements of the triathlon event contested. Development of an individualised fluid plan based on previous fluid balance observations may assist to avoid both dehydration and hyponatremia during prolonged triathlon racing.

  7. Draft Registration Implementation. Report Together with Dissenting Individual, Additional, and Separate Views. House of Representatives, Committee on Education and Labor, Ninety-eighth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Education and Labor.

    A report on a bill to delay the effective date for the denial of federal aid to students who have failed to comply with draft registration requirements is presented. The bill also directs the Comptroller General to conduct an ongoing study of the effectiveness of the Department of Defense Authorization Act of 1983 (Solomon/Hayakawa amendment) in…

  8. U.S. Experience with the Draft: Learning the Wrong Lessons

    DTIC Science & Technology

    2013-03-01

    W. Laws United States Army Reserve 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND...MSSA) to require the registration and possible conscription of women.15 Considerable public debate took place before Congress decided women would not...concluded “[i]n that event, the hypothetical draft the Court relied on to sustain the MSSA’s gender -based classification would presumably be of little

  9. Draft or Volunteer Army: Our Nation’s Best Interest

    DTIC Science & Technology

    2008-02-20

    equitably by all citizens. Wealthy Greeks who chose to avoid required military service could pay others to take their place. The Roman Army was composed...Warrior, Greek Hoplite, 480-323 BC” Osprey Publishing, 2000. 5 N. Bonias, “The Roman Army” version 1.0. 6 Nicolli Machiavelli, Columbia Electronic...state.”4 The conscription process in ancient Greece consisted of four stages : making the drafted list, notification, allowing for exemptions

  10. 78 FR 2868 - Draft Environmental Assessment for Rulemaking To Establish Minimum Sound Requirements for Hybrid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... require hybrid and electric passenger cars, light trucks, medium and heavy duty trucks and buses, low... Sound Requirements for Hybrid and Electric Vehicles AGENCY: National Highway Traffic Safety... minimum sound requirements for hybrid and electric vehicles. DATES: Comments must be received on or before...

  11. Aging management program of the reactor building concrete at Point Lepreau Generating Station

    NASA Astrophysics Data System (ADS)

    Aldea, C.-M.; Shenton, B.; Demerchant, M. M.; Gendron, T.

    2011-04-01

    In order for New Brunswick Power Nuclear (NBPN) to control the risks of degradation of the concrete reactor building at the Point Lepreau Generating Station (PLGS) the development of an aging management plan (AMP) was initiated. The intention of this plan was to determine the requirements for specific structural components of concrete of the reactor building that require regular inspection and maintenance to ensure the safe and reliable operation of the plant. The document is currently in draft form and presents an integrated methodology for the application of an AMP for the concrete of the reactor building. The current AMP addresses the reactor building structure and various components, such as joint sealant and liners that are integral to the structure. It does not include internal components housed within the structure. This paper provides background information regarding the document developed and the strategy developed to manage potential degradation of the concrete of the reactor building, as well as specific programs and preventive and corrective maintenance activities initiated.

  12. 46 CFR 35.20-7 - Verification of vessel compliance with applicable stability requirements-TB/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the vessels's trim and stability book, stability letter, Certificate of Inspection, and Load Line.... (b) When determining compliance with applicable stability requirements the vessel's draft, trim, and...

  13. 46 CFR 78.17-22 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... with all applicable stability requirements in the vessel's trim and stability book, stability letter... draft, trim, and stability must be determined as necessary and any stability calculations made in...

  14. 46 CFR 78.17-22 - Verification of vessel compliance with applicable stability requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... with all applicable stability requirements in the vessel's trim and stability book, stability letter... draft, trim, and stability must be determined as necessary and any stability calculations made in...

  15. 46 CFR 35.20-7 - Verification of vessel compliance with applicable stability requirements-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the vessels's trim and stability book, stability letter, Certificate of Inspection, and Load Line.... (b) When determining compliance with applicable stability requirements the vessel's draft, trim, and...

  16. [Model-based biofuels system analysis: a review].

    PubMed

    Chang, Shiyan; Zhang, Xiliang; Zhao, Lili; Ou, Xunmin

    2011-03-01

    Model-based system analysis is an important tool for evaluating the potential and impacts of biofuels, and for drafting biofuels technology roadmaps and targets. The broad reach of the biofuels supply chain requires that biofuels system analyses span a range of disciplines, including agriculture/forestry, energy, economics, and the environment. Here we reviewed various models developed for or applied to modeling biofuels, and presented a critical analysis of Agriculture/Forestry System Models, Energy System Models, Integrated Assessment Models, Micro-level Cost, Energy and Emission Calculation Models, and Specific Macro-level Biofuel Models. We focused on the models' strengths, weaknesses, and applicability, facilitating the selection of a suitable type of model for specific issues. Such an analysis was a prerequisite for future biofuels system modeling, and represented a valuable resource for researchers and policy makers.

  17. Light transport and general aviation aircraft icing research requirements

    NASA Technical Reports Server (NTRS)

    Breeze, R. K.; Clark, G. M.

    1981-01-01

    A short term and a long term icing research and technology program plan was drafted for NASA LeRC based on 33 separate research items. The specific items listed resulted from a comprehensive literature search, organized and assisted by a computer management file and an industry/Government agency survey. Assessment of the current facilities and icing technology was accomplished by presenting summaries of ice sensitive components and protection methods; and assessments of penalty evaluation, the experimental data base, ice accretion prediction methods, research facilities, new protection methods, ice protection requirements, and icing instrumentation. The intent of the research plan was to determine what icing research NASA LeRC must do or sponsor to ultimately provide for increased utilization and safety of light transport and general aviation aircraft.

  18. Managing uncertainty in metabolic network structure and improving predictions using EnsembleFBA

    PubMed Central

    2017-01-01

    Genome-scale metabolic network reconstructions (GENREs) are repositories of knowledge about the metabolic processes that occur in an organism. GENREs have been used to discover and interpret metabolic functions, and to engineer novel network structures. A major barrier preventing more widespread use of GENREs, particularly to study non-model organisms, is the extensive time required to produce a high-quality GENRE. Many automated approaches have been developed which reduce this time requirement, but automatically-reconstructed draft GENREs still require curation before useful predictions can be made. We present a novel approach to the analysis of GENREs which improves the predictive capabilities of draft GENREs by representing many alternative network structures, all equally consistent with available data, and generating predictions from this ensemble. This ensemble approach is compatible with many reconstruction methods. We refer to this new approach as Ensemble Flux Balance Analysis (EnsembleFBA). We validate EnsembleFBA by predicting growth and gene essentiality in the model organism Pseudomonas aeruginosa UCBPP-PA14. We demonstrate how EnsembleFBA can be included in a systems biology workflow by predicting essential genes in six Streptococcus species and mapping the essential genes to small molecule ligands from DrugBank. We found that some metabolic subsystems contributed disproportionately to the set of predicted essential reactions in a way that was unique to each Streptococcus species, leading to species-specific outcomes from small molecule interactions. Through our analyses of P. aeruginosa and six Streptococci, we show that ensembles increase the quality of predictions without drastically increasing reconstruction time, thus making GENRE approaches more practical for applications which require predictions for many non-model organisms. All of our functions and accompanying example code are available in an open online repository. PMID:28263984

  19. Managing uncertainty in metabolic network structure and improving predictions using EnsembleFBA.

    PubMed

    Biggs, Matthew B; Papin, Jason A

    2017-03-01

    Genome-scale metabolic network reconstructions (GENREs) are repositories of knowledge about the metabolic processes that occur in an organism. GENREs have been used to discover and interpret metabolic functions, and to engineer novel network structures. A major barrier preventing more widespread use of GENREs, particularly to study non-model organisms, is the extensive time required to produce a high-quality GENRE. Many automated approaches have been developed which reduce this time requirement, but automatically-reconstructed draft GENREs still require curation before useful predictions can be made. We present a novel approach to the analysis of GENREs which improves the predictive capabilities of draft GENREs by representing many alternative network structures, all equally consistent with available data, and generating predictions from this ensemble. This ensemble approach is compatible with many reconstruction methods. We refer to this new approach as Ensemble Flux Balance Analysis (EnsembleFBA). We validate EnsembleFBA by predicting growth and gene essentiality in the model organism Pseudomonas aeruginosa UCBPP-PA14. We demonstrate how EnsembleFBA can be included in a systems biology workflow by predicting essential genes in six Streptococcus species and mapping the essential genes to small molecule ligands from DrugBank. We found that some metabolic subsystems contributed disproportionately to the set of predicted essential reactions in a way that was unique to each Streptococcus species, leading to species-specific outcomes from small molecule interactions. Through our analyses of P. aeruginosa and six Streptococci, we show that ensembles increase the quality of predictions without drastically increasing reconstruction time, thus making GENRE approaches more practical for applications which require predictions for many non-model organisms. All of our functions and accompanying example code are available in an open online repository.

  20. 77 FR 45378 - Guidelines for Cases Requiring On-Scene Death Investigation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... Requiring On-Scene Death Investigation AGENCY: National Institute of Justice, Justice. ACTION: Notice and... for Medicolegal Death Investigation will make available to the general public a draft document entitled, ``Guidelines for Cases Requiring On-Scene Death Investigation''. The opportunity to provide...

  1. 76 FR 76932 - Public Hearings for 2017 and Later Model Year Light-Duty Vehicle Greenhouse Gas Emissions and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ...EPA and NHTSA are announcing public hearings to be held for the joint proposed rules ``2017 and Later Model Year Light-Duty Vehicle Greenhouse Gas Emissions and Corporate Average Fuel Economy Standards,'' published in the Federal Register on December 1, 2011. The agencies will also accept comment on NHTSA's Draft Environmental Impact Statement (Draft EIS), available on NHTSA's Web site at http:// www.nhtsa.gov/fuel-economy. Three hearings will be held, on January 17, January 19, and January 24, 2012. The agencies will assume that all oral comments presented at the hearing are addressed to the joint proposed rules only, unless speakers specifically reference NHTSA's Draft EIS in oral or written testimony.

  2. 78 FR 66366 - Draft Guidance for Industry: Use of Donor Screening Tests To Test Donors of Human Cells, Tissues...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ...The Food and Drug Administration (FDA) is announcing the availability of a draft document entitled ``Guidance for Industry: Use of Donor Screening Tests to Test Donors of Human Cells, Tissues, and Cellular and Tissue-Based Products (HCT/Ps) for Infection with Treponema pallidum (Syphilis),'' dated October 2013. The draft guidance document provides establishments that make donor eligibility determinations for donors of HCT/Ps (HCT/P Establishments), with updated recommendations concerning donor testing for evidence of Treponema pallidum (T. pallidum) infection, the etiologic agent of syphilis. HCT/P Establishments must, as required under Federal regulations, test a donor specimen for evidence of T. pallidum infection using appropriate FDA-licensed, approved, or cleared donor screening tests, in accordance with the manufacturer's instructions, unless an exception to this requirement applies. The draft guidance clarifies that FDA does not consider diagnostic tests or pre-amendment devices (which have not been licensed, approved, or cleared) to be adequate for use in donor testing for T. pallidum infection under the criteria specified in Federal regulations. The recommendations in this guidance, when finalized, will supersede those recommendations for testing HCT/P donors for evidence of T. pallidum infection contained in the document entitled ``Guidance for Industry: Eligibility Determination for Donors of Human Cells, Tissues, and Cellular and Tissue-Based Products (HCT/Ps),'' dated August 2007.

  3. Refining a taxonomy for guideline implementation: results of an exercise in abstract classification

    PubMed Central

    2013-01-01

    Background To better understand the efficacy of various implementation strategies, improved methods for describing and classifying the nature of these strategies are urgently required. The aim of this study was to develop and pilot the feasibility of a taxonomy to classify the nature and content of implementation strategies. Methods A draft implementation taxonomy was developed based on the Cochrane Effective Practice and Organisation of Care (EPOC) data collection checklist. The draft taxonomy had four domains (professional, financial, organisational and regulatory) covering 49 distinct strategies. We piloted the draft taxonomy by using it to classify the implementation strategies described in the conference abstracts of the implementation stream of the 2010 Guideline International Network Conference. Five authors classified the strategies in each abstract individually. Final categorisation was then carried out in a face-to-face consensus meeting involving three authors. Results The implementation strategies described in 71 conference abstracts were classified. Approximately 15.5% of abstracts utilised strategies that could not be categorised using the draft taxonomy. Of those strategies that could be categorised, the majority were professionally focused (57%). A total of 41% of projects used only one implementation strategy, with 29% using two and 31% three or more. The three most commonly used strategies were changes in quality assurance, quality improvement and/or performance measurement systems, changes in information and communication technology, and distribution of guideline materials (via hard-copy, audio-visual and/or electronic means). Conclusions Further refinement of the draft taxonomy is required to provide hierarchical dimensions and granularity, particularly in the areas of patient-focused interventions, those concerned with audit and feedback and quality improvement, and electronic forms of implementation, including electronic decision support. PMID:23497520

  4. Refining a taxonomy for guideline implementation: results of an exercise in abstract classification.

    PubMed

    Mazza, Danielle; Bairstow, Phillip; Buchan, Heather; Chakraborty, Samantha Paubrey; Van Hecke, Oliver; Grech, Cathy; Kunnamo, Ilkka

    2013-03-15

    To better understand the efficacy of various implementation strategies, improved methods for describing and classifying the nature of these strategies are urgently required. The aim of this study was to develop and pilot the feasibility of a taxonomy to classify the nature and content of implementation strategies. A draft implementation taxonomy was developed based on the Cochrane Effective Practice and Organisation of Care (EPOC) data collection checklist. The draft taxonomy had four domains (professional, financial, organisational and regulatory) covering 49 distinct strategies. We piloted the draft taxonomy by using it to classify the implementation strategies described in the conference abstracts of the implementation stream of the 2010 Guideline International Network Conference. Five authors classified the strategies in each abstract individually. Final categorisation was then carried out in a face-to-face consensus meeting involving three authors. The implementation strategies described in 71 conference abstracts were classified. Approximately 15.5% of abstracts utilised strategies that could not be categorised using the draft taxonomy. Of those strategies that could be categorised, the majority were professionally focused (57%). A total of 41% of projects used only one implementation strategy, with 29% using two and 31% three or more. The three most commonly used strategies were changes in quality assurance, quality improvement and/or performance measurement systems, changes in information and communication technology, and distribution of guideline materials (via hard-copy, audio-visual and/or electronic means). Further refinement of the draft taxonomy is required to provide hierarchical dimensions and granularity, particularly in the areas of patient-focused interventions, those concerned with audit and feedback and quality improvement, and electronic forms of implementation, including electronic decision support.

  5. Evaluation of commercially available aqueous batch immersion cleaning products. Technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bevilacqua, P.; Clark, K.G.

    1996-01-10

    With the production of Class I Ozone Depleting Substances scheduled to cease in January 1996, it has become necessary to identify suitable replacements for chlorofluorocarbon (CFC-113, Freon 113) vapor degreasing operations currently used to clean avionics components in Navy aircraft maintenance facilities. In this study, one potential option, the use of aqueous cleaning agents, was explored. Commercially available industrial aqueous cleaning agents were evaluated for cleaning capability on simulated operational soils and effects on aircraft materials. Two cleaning agents, Armakleen 2001 and Crest ABS 901, were recommended as a result of this work, and a Military Specification was drafted outliningmore » performance requirements.« less

  6. 75 FR 80544 - NUREG-1953, Confirmatory Thermal-Hydraulic Analysis To Support Specific Success Criteria in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... To Support Specific Success Criteria in the Standardized Plant Analysis Risk Models--Surry and Peach... Specific Success Criteria in the Standardized Plant Analysis Risk Models--Surry and Peach Bottom, Draft..., ``Confirmatory Thermal-Hydraulic Analysis to Support Specific Success Criteria in the Standardized Plant Analysis...

  7. 78 FR 23289 - Public Review of Draft National Shoreline Data Content Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ...The Federal Geographic Data Committee (FGDC) is conducting a public review of the draft National Shoreline Data Content Standard. The FGDC has developed a draft National Shoreline Data Content Standard that provides a framework for shoreline data development, sharing of data, and shoreline data transformation and fusion. The FGDC Coastal and Marine Spatial Data Subcommittee, chaired by the National Oceanic and Atmospheric Administration (NOAA), sponsored development of the draft standard. The FGDC Coordination Group, comprised of representatives of Federal agencies, has approved releasing this draft standard for public review and comment. The draft National Shoreline Data Content Standard defines attributes or elements that are common for shoreline data development and provides suggested domains for the elements. The functional scope includes definition of data models, schemas, entities, relationships, definitions, and crosswalks to related standards. The draft National Shoreline Data Content Standard is intended to enhance the shoreline framework by providing technical guidance on shoreline semantics, data structures and their relationships to builders and users of shoreline data. The geographical scope of the draft standard comprises all shorelines of navigable waters within the United States and its territories. The primary intended users of the National Shoreline Data Content Standard are the mapping, shoreline engineering, coastal zone management, flood insurance, and natural resource management communities. The FGDC invites all stakeholders to comment on this draft standard to ensure that it meets their needs. The draft National Shoreline Data Content Standard may be downloaded from https://www.fgdc.gov/standards/projects/FGDC-standards- projects/shoreline-data-content/ revisedDraftNationalShorelineDataContentStandard. Comments shall be submitted using the content template at http://www.fgdc.gov/standards/ process/standards-directives/template.doc. Instructions for completing the comment template are found in FGDC Standards Directive 2d, Standards Working Group Review Guidelines: Review Comment Template, http://www.fgdc.gov/standards/process/standards-directives/directive- 2d-standards-working-group-review-guidelines-review-comment-template. Comments that concern specific issues/changes/additions may result in revisions to the National Shoreline Data Content Standard. Reviewers may obtain information about how comments were addressed upon request. After formal endorsement of the standard by the FGDC, the National Shoreline Data Content Standard and a summary analysis of the changes will be made available to the public on the FGDC Web site, www.fgdc.gov.

  8. 75 FR 30008 - Commission Information Collection Activities; Comment Request; Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-28

    ... by requiring public utilities, working through the North American Electric Reliability Corporation.... The Commission required a NERC/NAESB \\2\\ team to draft and review Order No. 890 reliability standards... NERC, were to revise reliability standards to require the exchange of data and coordination among...

  9. Open consent, biobanking and data protection law: can open consent be 'informed' under the forthcoming data protection regulation?

    PubMed

    Hallinan, Dara; Friedewald, Michael

    2015-01-01

    This article focuses on whether a certain form of consent used by biobanks--open consent--is compatible with the Proposed Data Protection Regulation. In an open consent procedure, the biobank requests consent once from the data subject for all future research uses of genetic material and data. However, as biobanks process personal data, they must comply with data protection law. Data protection law is currently undergoing reform. The Proposed Data Protection Regulation is the culmination of this reform and, if voted into law, will constitute a new legal framework for biobanking. The Regulation puts strict conditions on consent--in particular relating to information which must be given to the data subject. It seems clear that open consent cannot meet these requirements. 4 categories of information cannot be provided with adequate specificity: purpose, recipient, possible third country transfers, data collected. However, whilst open consent cannot meet the formal requirements laid out by the Regulation, this is not to say that these requirements are substantially undebateable. Two arguments could be put forward suggesting the applicable consent requirements should be rethought. First, from policy documents regarding the drafting process, it seems that the informational requirements in the Regulation are so strict in order to protect the data subject from risks inherent in the use of the consent mechanism in a certain context--exemplified by the online context. There are substantial differences between this context and the biobanking context. Arguably, a consent transaction in the biobanking does not present the same type of risk to the data subject. If the risks are different, then perhaps there are also grounds for a reconsideration of consent requirements? Second, an argument can be made that the legislator drafted the Regulation based on certain assumptions as to the nature of 'data'. The authors argue that these assumptions are difficult to apply to genetic data and accordingly a different approach to consent might be preferable. Such an approach might be more open consent friendly.

  10. WHO Expert Committee on Specifications for Pharmaceutical Preparations.

    PubMed

    2005-01-01

    This report presents the recommendations of an international group of experts convened by the World Health Organization to consider matters concerning the quality assurance of pharmaceuticals and specifications for drug substances and dosage forms. Of particular relevance to drug regulatory authorities and pharmaceutical manufacturers, this report discusses the monographs on antiretrovirals proposed for inclusion in The International Pharmacopoeia and specifications for radiopharmaceuticals, quality specifications for antituberculosis drugs and the revision of the monograph on artemisinin derivatives, as well as quality control of reference materials, good manufacturing practices (GMP), inspection, distribution and trade and other aspects of quality assurance of pharmaceuticals, and regulatory issues. The report is complemented by a number of annexes, including an amendment to good manufacturing practices: main principles regarding the requirement for the sampling of starting materials, guidelines on good manufacturing practices regarding water for pharmaceutical use, guidelines on the sampling of pharmaceutical products and related materials and draft guidelines for registration of fixed-dose combination medicinal products.

  11. 77 FR 38779 - Notice of Availability of Draft Environmental Impact Statement for the Proposed Mather Specific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... Environmental Impact Statement for the Proposed Mather Specific Plan Project, Sacramento County, CA, Corps...-acre Mather Specific Plan area, Sacramento County, California (note that approximately 2,554 acres of the Plan area contains existing development, primarily Mather Airport, a Commerce Center, a...

  12. Navy Health Care Strategic Planning Process: A Draft Functional Description

    DTIC Science & Technology

    1993-09-01

    56 a. Equipment Environment ................................................... 56...b. Support Software Environment .............................................. 56 c. Communications Requirements... Environment .................................................................. 73 a. AIS Equipment Environment

  13. Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building.

    PubMed

    Dickmann, Petra; Sheeley, Heather; Lightfoot, Nigel

    2015-01-01

    Laboratory capacity building is characterized by a paradox between endemicity and resources: countries with high endemicity of pathogenic agents often have low and intermittent resources (water, electricity) and capacities (laboratories, trained staff, adequate regulations). Meanwhile, countries with low endemicity of pathogenic agents often have high-containment facilities with costly infrastructure and maintenance governed by regulations. The common practice of exporting high biocontainment facilities and standards is not sustainable and concerns about biosafety and biosecurity require careful consideration. A group at Chatham House developed a draft conceptual framework for safer, more secure, and sustainable laboratory capacity building. The draft generic framework is guided by the phrase "LOCAL - PEOPLE - MAKE SENSE" that represents three major principles: capacity building according to local needs (local) with an emphasis on relationship and trust building (people) and continuous outcome and impact measurement (make sense). This draft generic framework can serve as a blueprint for international policy decision-making on improving biosafety and biosecurity in laboratory capacity building, but requires more testing and detailing development.

  14. The new World Organisation for Animal Health standards on avian influenza and international trade.

    PubMed

    Thiermann, Alex B

    2007-03-01

    In 2002, the World Organisation for Animal Health began a review of the chapter on avian influenza by convening a group of experts to revise the most recent scientific literature. The group drafted the initial text that would provide the necessary recommendations on avian influenza control and prevention measures. The main objectives of this draft were to provide clear notification criteria, as well as commodity-specific, risk-based mitigating measures, that would provide safety when trading and encourage transparent reporting.

  15. Emergency Cooling of Nuclear Power Plant Reactors With Heat Removal By a Forced-Draft Cooling Tower

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Murav’ev, V. P., E-mail: murval1@mail.ru

    The feasibility of heat removal during emergency cooling of a reactor by a forced-draft cooling tower with accumulation of the peak heat release in a volume of precooled water is evaluated. The advantages of a cooling tower over a spray cooling pond are demonstrated: it requires less space, consumes less material, employs shorter lines in the heat removal system, and provides considerably better protection of the environment from wetting by entrained moisture.

  16. The Governance of the City University of New York A System at Odds with Itself

    DTIC Science & Technology

    2000-01-01

    provided thoughtful and incisive commentary on drafts of this document. Early drafts also benefited from the reviews of task force staff mem - bers...requirements on the qualifications of mem - bers of the board. In particular, the law does not attempt to ensure that trustees have a measure of...establishing a blue-ribbon process for the appointment of the mem - bers of the Board of Trustees. Such a process would involve the cre- ation of

  17. A mixed-methods research approach to the review of competency standards for orthotist/prosthetists in Australia.

    PubMed

    Ash, Susan; O'Connor, Jackie; Anderson, Sarah; Ridgewell, Emily; Clarke, Leigh

    2015-06-01

    The requirement for an allied health workforce is expanding as the global burden of disease increases internationally. To safely meet the demand for an expanded workforce of orthotist/prosthetists in Australia, competency based standards, which are up-to-date and evidence-based, are required. The aims of this study were to determine the minimum level for entry into the orthotic/prosthetic profession; to develop entry level competency standards for the profession; and to validate the developed entry-level competency standards within the profession nationally, using an evidence-based approach. A mixed-methods research design was applied, using a three-step sequential exploratory design, where step 1 involved collecting and analyzing qualitative data from two focus groups; step 2 involved exploratory instrument development and testing, developing the draft competency standards; and step 3 involved quantitative data collection and analysis - a Delphi survey. In stage 1 (steps 1 and 2), the two focus groups - an expert and a recent graduate group of Australian orthotist/prosthetists - were led by an experienced facilitator, to identify gaps in the current competency standards and then to outline a key purpose, and work roles and tasks for the profession. The resulting domains and activities of the first draft of the competency standards were synthesized using thematic analysis. In stage 2 (step 3), the draft-competency standards were circulated to a purposive sample of the membership of the Australian Orthotic Prosthetic Association, using three rounds of Delphi survey. A project reference group of orthotist/prosthetists reviewed the results of both stages. In stage 1, the expert (n = 10) and the new graduate (n = 8) groups separately identified work roles and tasks, which formed the initial draft of the competency standards. Further drafts were refined and performance criteria added by the project reference group, resulting in the final draft-competency standards. In stage 2, the final draft-competency standards were circulated to 56 members (n = 44 final round) of the Association, who agreed on the key purpose, 6 domains, 18 activities, and 68 performance criteria of the final competency standards. This study outlines a rigorous and evidence-based mixed-methods approach for developing and endorsing professional competency standards, which is representative of the views of the profession of orthotist/prosthetists.

  18. Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society Statement.

    PubMed

    Casanueva, Felipe F; Barkan, Ariel L; Buchfelder, Michael; Klibanski, Anne; Laws, Edward R; Loeffler, Jay S; Melmed, Shlomo; Mortini, Pietro; Wass, John; Giustina, Andrea

    2017-10-01

    With the goal of generate uniform criteria among centers dealing with pituitary tumors and to enhance patient care, the Pituitary Society decided to generate criteria for developing Pituitary Tumors Centers of Excellence (PTCOE). To develop that task, a group of ten experts served as a Task Force and through two years of iterative work an initial draft was elaborated. This draft was discussed, modified and finally approved by the Board of Directors of the Pituitary Society. Such document was presented and debated at a specific session of the Congress of the Pituitary Society, Orlando 2017, and suggestions were incorporated. Finally the document was distributed to a large group of global experts that introduced further modifications with final endorsement. After five years of iterative work a document with the ideal criteria for a PTCOE is presented. Acknowledging that very few centers in the world, if any, likely fulfill the requirements here presented, the document may be a tool to guide improvements of care delivery to patients with pituitary disorders. All these criteria must be accommodated to the regulations and organization of Health of a given country.

  19. Draft genome of the medaka fish: a comprehensive resource for medaka developmental genetics and vertebrate evolutionary biology.

    PubMed

    Takeda, Hiroyuki

    2008-06-01

    The medaka Oryzias latipes is a small egg-laying freshwater teleost, and has become an excellent model system for developmental genetics and evolutionary biology. The medaka genome is relatively small in size, approximately 800 Mb, and the genome sequencing project was recently completed by Japanese research groups, providing a high-quality draft genome sequence of the inbred Hd-rR strain of medaka. In this review, I present an overview of the medaka genome project including genome resources, followed by specific findings obtained with the medaka draft genome. In particular, I focus on the analysis that was done by taking advantage of the medaka system, such as the sex chromosome differentiation and the regional history of medaka species using single nucleotide polymorphisms as genomic markers.

  20. Relationship between concussion history and neurocognitive test performance in National Football League draft picks.

    PubMed

    Solomon, Gary S; Kuhn, Andrew

    2014-04-01

    There are limited empirical data available regarding the relationship between concussion history and neurocognitive functioning in active National Football League (NFL) players in general and NFL draft picks in particular. Potential NFL draft picks undergo 2 neurocognitive tests at the National Invitational Camp (Scouting Combine) every year: the Wonderlic and, since 2011, the Immediate Post-concussion Assessment and Cognitive Testing (ImPACT). After conclusion of the combine and before the draft, NFL teams invite potential draft picks to their headquarters for individual visits where further assessment may occur. To examine the relationship between concussion history and neurocognitive performance (ImPACT and Wonderlic) in a sample of elite NFL draft picks. Cohort study; Level of evidence, 3. Over 7 years, 226 potential draft picks were invited to visit a specific NFL team's headquarters after the combine. The athletes were divided into 3 groups based on self-reported concussion history: no prior concussions, 1 prior concussion, and 2 or more prior concussions. Neurocognitive measures of interest included Wonderlic scores (provided by the NFL team) and ImPACT composite scores (administered either at the combine or during a visit to the team headquarters). The relationship between concussion history and neurocognitive scores was assessed, as were the relationships among the 2 neurocognitive tests. Concussion history had no relationship to neurocognitive performance on either the Wonderlic or ImPACT. Concussion history did not affect performance on either neurocognitive test, suggesting that for this cohort, a history of concussion may not have adverse effects on neurocognitive functioning as measured by these 2 tests. This study reveals no correlation between concussion history and neurocognitive test scores (ImPACT, Wonderlic) in soon-to-be active NFL athletes.

  1. 76 FR 5215 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... Compliance with Packaging Requirements for Shipment and Receipt of Radioactive Material,'' is temporarily... Code of Federal Regulations, Part 71, ``Packaging and Transportation of Radioactive Material'' (10 CFR... Compliance with Packaging Requirements for Shipments of Radioactive Materials,'' as an acceptable process for...

  2. Klebsormidium flaccidum genome reveals primary factors for plant terrestrial adaptation

    PubMed Central

    Hori, Koichi; Maruyama, Fumito; Fujisawa, Takatomo; Togashi, Tomoaki; Yamamoto, Nozomi; Seo, Mitsunori; Sato, Syusei; Yamada, Takuji; Mori, Hiroshi; Tajima, Naoyuki; Moriyama, Takashi; Ikeuchi, Masahiko; Watanabe, Mai; Wada, Hajime; Kobayashi, Koichi; Saito, Masakazu; Masuda, Tatsuru; Sasaki-Sekimoto, Yuko; Mashiguchi, Kiyoshi; Awai, Koichiro; Shimojima, Mie; Masuda, Shinji; Iwai, Masako; Nobusawa, Takashi; Narise, Takafumi; Kondo, Satoshi; Saito, Hikaru; Sato, Ryoichi; Murakawa, Masato; Ihara, Yuta; Oshima-Yamada, Yui; Ohtaka, Kinuka; Satoh, Masanori; Sonobe, Kohei; Ishii, Midori; Ohtani, Ryosuke; Kanamori-Sato, Miyu; Honoki, Rina; Miyazaki, Daichi; Mochizuki, Hitoshi; Umetsu, Jumpei; Higashi, Kouichi; Shibata, Daisuke; Kamiya, Yuji; Sato, Naoki; Nakamura, Yasukazu; Tabata, Satoshi; Ida, Shigeru; Kurokawa, Ken; Ohta, Hiroyuki

    2014-01-01

    The colonization of land by plants was a key event in the evolution of life. Here we report the draft genome sequence of the filamentous terrestrial alga Klebsormidium flaccidum (Division Charophyta, Order Klebsormidiales) to elucidate the early transition step from aquatic algae to land plants. Comparison of the genome sequence with that of other algae and land plants demonstrate that K. flaccidum acquired many genes specific to land plants. We demonstrate that K. flaccidum indeed produces several plant hormones and homologues of some of the signalling intermediates required for hormone actions in higher plants. The K. flaccidum genome also encodes a primitive system to protect against the harmful effects of high-intensity light. The presence of these plant-related systems in K. flaccidum suggests that, during evolution, this alga acquired the fundamental machinery required for adaptation to terrestrial environments. PMID:24865297

  3. Findings from a novel approach to publication guideline revision: user road testing of a draft version of SQUIRE 2.0.

    PubMed

    Davies, Louise; Donnelly, Kyla Z; Goodman, Daisy J; Ogrinc, Greg

    2016-04-01

    The Standards for Quality Improvement Reporting Excellence (SQUIRE) Guideline was published in 2008 (SQUIRE 1.0) and was the first publication guideline specifically designed to advance the science of healthcare improvement. Advances in the discipline of improvement prompted us to revise it. We adopted a novel approach to the revision by asking end-users to 'road test' a draft version of SQUIRE 2.0. The aim was to determine whether they understood and implemented the guidelines as intended by the developers. Forty-four participants were assigned a manuscript section (ie, introduction, methods, results, discussion) and asked to use the draft Guidelines to guide their writing process. They indicated the text that corresponded to each SQUIRE item used and submitted it along with a confidential survey. The survey examined usability of the Guidelines using Likert-scaled questions and participants' interpretation of key concepts in SQUIRE using open-ended questions. On the submitted text, we evaluated concordance between participants' item usage/interpretation and the developers' intended application. For the survey, the Likert-scaled responses were summarised using descriptive statistics and the open-ended questions were analysed by content analysis. Consistent with the SQUIRE Guidelines' recommendation that not every item be included, less than one-third (n=14) of participants applied every item in their section in full. Of the 85 instances when an item was partially used or was omitted, only 7 (8.2%) of these instances were due to participants not understanding the item. Usage of Guideline items was highest for items most similar to standard scientific reporting (ie, 'Specific aim of the improvement' (introduction), 'Description of the improvement' (methods) and 'Implications for further studies' (discussion)) and lowest (<20% of the time) for those unique to healthcare improvement (ie, 'Assessment methods for context factors that contributed to success or failure' and 'Costs and strategic trade-offs'). Items unique to healthcare improvement, specifically 'Evolution of the improvement', 'Context elements that influenced the improvement', 'The logic on which the improvement was based', 'Process and outcome measures', demonstrated poor concordance between participants' interpretation and developers' intended application. User testing of a draft version of SQUIRE 2.0 revealed which items have poor concordance between developer intent and author usage, which will inform final editing of the Guideline and development of supporting supplementary materials. It also identified the items that require special attention when teaching about scholarly writing in healthcare improvement. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  4. Florida-specific NTCIP management information base (MIB) for closed-circuit television (CCTV) camera : final draft.

    DOT National Transportation Integrated Search

    2009-01-01

    Description: This following MIB has been developed for use by FDOT. This : proposed Florida-Specific NTCIP Management Information Base (MIB) For : Closed-Circuit Television (CCTV) Camera MIB is based on the following : documentations: : NTCIP 120...

  5. 21 CFR 211.160 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... drafted by the appropriate organizational unit and reviewed and approved by the quality control unit. The...: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Laboratory Controls § 211.160... procedures, or other laboratory control mechanisms required by this subpart, including any change in such...

  6. 75 FR 35508 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-22

    ... Systems and Networks,'' requires licensees to develop cyber-security plans and programs to protect critical digital assets, including digital safety systems, from malicious cyber attacks. Regulatory Guide 5.71, ``Cyber Security Programs for Nuclear Facilities,'' provides guidance to meet the requirements of...

  7. Evolution of modern approaches to express uncertainty in measurement

    NASA Astrophysics Data System (ADS)

    Kacker, Raghu; Sommer, Klaus-Dieter; Kessel, Rüdiger

    2007-12-01

    An object of this paper is to discuss the logical development of the concept of uncertainty in measurement and the methods for its quantification from the classical error analysis to the modern approaches based on the Guide to the Expression of Uncertainty in Measurement (GUM). We review authoritative literature on error analysis and then discuss its limitations which motivated the experts from the International Committee for Weights and Measures (CIPM), the International Bureau of Weights and Measures (BIPM) and various national metrology institutes to develop specific recommendations which form the basis of the GUM. We discuss the new concepts introduced by the GUM and their merits and limitations. The limitations of the GUM led the BIPM Joint Committee on Guides in Metrology to develop an alternative approach—the draft Supplement 1 to the GUM (draft GUM-S1). We discuss the draft GUM-S1 and its merits and limitations. We hope this discussion will lead to a more effective use of the GUM and the draft GUM-S1 and stimulate investigations leading to further improvements in the methods to quantify uncertainty in measurement.

  8. Draft Plan for Characterizing Commercial Data Products in Support of Earth Science Research

    NASA Technical Reports Server (NTRS)

    Ryan, Robert E.; Terrie, Greg; Berglund, Judith

    2006-01-01

    This presentation introduces a draft plan for characterizing commercial data products for Earth science research. The general approach to the commercial product verification and validation includes focused selection of a readily available commercial remote sensing products that support Earth science research. Ongoing product verification and characterization will question whether the product meets specifications and will examine its fundamental properties, potential and limitations. Validation will encourage product evaluation for specific science research and applications. Specific commercial products included in the characterization plan include high-spatial-resolution multispectral (HSMS) imagery and LIDAR data products. Future efforts in this process will include briefing NASA headquarters and modifying plans based on feedback, increased engagement with the science community and refinement of details, coordination with commercial vendors and The Joint Agency Commercial Imagery Evaluation (JACIE) for HSMS satellite acquisitions, acquiring waveform LIDAR data and performing verification and validation.

  9. Child-Specific Exposure Factors Handbook (2006, External Review Draft)

    EPA Science Inventory

    Cover of the Child-Specific Exposure Factors Handbook Children are often more heavily exposed to environmental toxicants than adults. They consume more...

  10. Technical and Occupational Shops.

    ERIC Educational Resources Information Center

    Ontario Dept. of Education, Toronto. School Planning and Building Research Section.

    This booklet presents suggested plans and specifications for and discusses facilities common to technical and occupational shops. Drawings, room plans, and text illustrate specifications for drafting rooms, a welding shop, an automechanics shop, an auto body shop, and a high school greenhouse. Also included are facility designs for agricultural…

  11. 78 FR 68360 - Unmanned Aircraft System Test Site Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-14

    ...-0061] Unmanned Aircraft System Test Site Program AGENCY: Federal Aviation Administration (FAA), DOT...'') test site program; response to comments. SUMMARY: On February 22, 2013 the FAA published and requested public comment on the proposed privacy requirements (the ``Draft Privacy Requirements'') for UAS test...

  12. 76 FR 57060 - International Cooperation on Harmonisation of Technical Requirements for Registration of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0588] International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products; Draft Guidance for Industry on Pharmacovigilance of Veterinary Medicinal Products: Electronic...

  13. Third phase of pocket-sized electronic dosimeter testing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fox, R.A.; Hooker, C.D.; Hogan, B.T.

    1982-05-01

    The experiences of industrial radiographers have indicated that electronic radiation-warning devices become inoperative when they are used under some types of ambient conditions. This report, as a follow-up to NUREG/CR-0554 and NUREG/CR-1452, documents the nature of tests performed on several additional commercially available models. None of the four models tested passed the tests for ruggedness and severe environmental conditions. However, all models passed most of the requirements of a Health Physics Society draft standard of performance specifications for these devices. The test procedures used in the project and the results obtained are discussed. Conclusions from the tests and recommendations concerningmore » potentially useful modifications to existing devices are presented.« less

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wohlgemuth, John; Silverman, Timothy; Miller, David C.

    This paper describes an effort to inspect and evaluate PV modules in order to determine what failure or degradation modes are occurring in field installations. This paper will report on the results of six site visits, including the Sacramento Municipal Utility District (SMUD) Hedge Array, Tucson Electric Power (TEP) Springerville, Central Florida Utility, Florida Solar Energy Center (FSEC), the TEP Solar Test Yard, and University of Toledo installations. The effort here makes use of a recently developed field inspection data collection protocol, and the results were input into a corresponding database. The results of this work have also been usedmore » to develop a draft of the IEC standard for climate and application specific accelerated stress testing beyond module qualification. TEP Solar Test Yard, and University of Toledo installations. The effort here makes use of a recently developed field inspection data collection protocol, and the results were input into a corresponding database. The results of this work have also been used to develop a draft of the IEC standard for climate and application specific accelerated stress testing beyond module qualification. TEP Solar Test Yard, and University of Toledo installations. The effort here makes use of a recently developed field inspection data collection protocol, and the results were input into a corresponding database. The results of this work have also been used to develop a draft of the IEC standard for climate and application specific accelerated stress testing beyond module qualification.« less

  15. Working draft of the FDA GMP final rule (Part II).

    PubMed

    Donawa, M E

    1995-11-01

    Part I of this two-part series provided information on the proposed design control provisions of the US Food and Drug Administration's (FDA) working draft of the final rule for new good manufacturing practice regulations for medical devices. The final rule could be published in April or May 1996. It would be in force 180 days after the date of publication. Design control requirements may become effective some months later. This article describes recommended modifications of three provisions that have been intensely discussed during recent FDA-sponsored public meetings.

  16. IRIS Toxicological Review of Ammonia (Interagency Science ...

    EPA Pesticide Factsheets

    On June 1, 2012, the draft Toxicological Review of Ammonia and the draft charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science consultation materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Ammonia and the charge to external peer reviewers, are posted on this site. EPA is undertaking an Integrated Risk Information System (IRIS) health assessment for ammonia. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment paradigm, i.e., hazard identification and dose-response evaluation. IRIS assessments are used in combination with specific situational exposure assessment information to evaluate potential public health risk associated with environmental contaminants.

  17. LED street lighting evaluation -- phase II : LED specification and life-cycle cost analysis.

    DOT National Transportation Integrated Search

    2015-01-01

    Phase II of this study focused on developing a draft specification for LED luminaires to be used by IDOT : and a life-cycle cost analysis (LCCA) tool for solid state lighting technologies. The team also researched the : latest developments related to...

  18. ISO radiation sterilization standards

    NASA Astrophysics Data System (ADS)

    Lambert, Byron J.; Hansen, Joyce M.

    1998-06-01

    This presentation provides an overview of the current status of the ISO radiation sterilization standards. The ISO standards are voluntary standards which detail both the validation and routine control of the sterilization process. ISO 11137 was approved in 1994 and published in 1995. When reviewing the standard you will note that less than 20% of the standard is devoted to requirements and the remainder is guidance on how to comply with the requirements. Future standards developments in radiation sterilization are being focused on providing additional guidance. The guidance that is currently provided in informative annexes of ISO 11137 includes: device/packaging materials, dose setting methods, and dosimeters and dose measurement, currently, there are four Technical Reports being developed to provide additional guidance: 1. AAMI Draft TIR, "Radiation Sterilization Material Qualification" 2. ISO TR 13409-1996, "Sterilization of health care products — Radiation sterilization — Substantiation of 25 kGy as a sterilization dose for small or infrequent production batches" 3. ISO Draft TR, "Sterilization of health care products — Radiation sterilization Selection of a sterilization dose for a single production batch" li]4. ISO Draft TR, "Sterilization of health care products — Radiation sterilization-Product Families, Plans for Sampling and Frequency of Dose Audits."

  19. 76 FR 3646 - Safety Requirements and Manning Exemption Eligibility on Distant Water Tuna Fleet Vessels

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ...Pursuant to Section 904 of the 2010 Coast Guard Authorization Act, the Coast Guard announces the availability of a draft policy regarding distant water tuna fleet vessels manning exemption eligibility and safety requirements. We request your comments on the Safety Requirements and Manning Exemption Eligibility on Distant Water Tuna Fleet Vessels.

  20. Environmental Quality Technology Demonstration, Evaluation and Transfer Activities

    DTIC Science & Technology

    1996-12-02

    and Appropriate Requirements) and ARAR support documentation for interim and final Installation Restoration Program (IRP) remedial actions . During the...Relevant and Appropriate Requirements (ARARs) for Fort Devens , Massachusetts. Delivered Federal Environmental Legislative Power Curve in hard copy and... Remedial Actions . Delivered revised tables for Desk Guide on Interpretation of Applicable or Relevant and Appropriate Requirements — Interim Draft

  1. 16 CFR § 1021.7 - Coordination of environmental review with CPSC procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Commission action. The preparation and completion of assessments and statements required by this part shall... assessment on a proposed rulemaking action requiring environmental review shall be available to the... throughout the Commission's decisionmaking process. (c) Draft EISs or findings of no significant impact...

  2. 78 FR 16483 - Notice of Availability of the Draft Uranium Leasing Program Programmatic Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ...The U.S. Department of Energy (DOE) announces the availability of the Draft Uranium Leasing Program Programmatic Environmental Impact Statement (Draft ULP PEIS, DOE/EIS-0472D), for public comment. DOE is also announcing the dates, times, and locations for public hearings to receive comments on the Draft ULP PEIS. DOE has prepared the Draft ULP PEIS pursuant to the National Environmental Policy Act of 1969 (NEPA), the Council on Environmental Quality's (CEQ's) NEPA regulations (40 CFR parts 1500-1508), and DOE's NEPA implementing procedures (10 CFR part 1021) to analyze the reasonably foreseeable potential environmental impacts, including the site-specific impacts, of the range of reasonable alternatives for the management of the ULP. DOE's ULP administers 31 tracts of land covering an aggregate of approximately 25,000 acres (10,000 ha) in Mesa, Montrose, and San Miguel Counties in western Colorado for exploration, mine development, operations, and reclamation of uranium mines. The cooperating agencies on this ULP PEIS are the: U.S. Department of the Interior (DOI), Bureau of Land Management (BLM); U.S. Environmental Protection Agency (EPA); Colorado Department of Transportation; Colorado Division of Reclamation, Mining, and Safety; Colorado Parks and Wildlife ; Mesa County Commission; Montrose County Commission; San Juan County Commission; San Miguel County Board of Commissioners; Pueblo of Acoma Tribe; Pueblo de Cochiti Tribe; Pueblo de Isleta Tribe; Navajo Nation; and Southern Ute Indian Tribe.

  3. The development of European standard (CEN) methods in support of European Directives for plastics materials and articles intended to come into contact with foodstuff.

    PubMed

    Ashby, R

    1994-01-01

    CEC Directives have been implemented for plastics materials and articles intended to come into contact with foodstuffs. These introduce limits upon the overall migration from plastics into food and food simulants. In addition, specific migration limits or composition limits for free monomer in the final article, have been set for some monomers. Agreed test methods are required to allow these Directives to be respected. CEN, the European Committee for Standardization, has created a working group to develop suitable test methods. This is 'Working Group 5, Chemical Methods of Test', of CEN Technical Committee TC 194, Utensils in contact with food. This group has drafted a ten part standard for determining overall migration into aqueous and fatty food simulants by total immersion, by standard cell, by standard pouch and by filling. This draft standard has been approved by CEN TC 194 for circulation for public comment as a provisional standard, i.e. as an ENV. Further parts of this standard are in preparation for determining overall migration at high temperatures, etc. Simultaneously, Working Group 5 is cooperating with the BCR (Community Bureau of Reference) to produce reference materials with certified values of overall migration. CEN TC 194 Working Group 5 is also drafting methods for monomers subject to limitation in Directive 90/128/EEC. Good progress is being made on the monomers of highest priority but it is recognized that developing methods for all the monomers subject to limitation would take many years. Therefore, collaboration with the BCR, the Council of Europe and others is taking place to accelerate method development.

  4. 77 FR 44617 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ...-24: Dean Peterson. Draft Advisory Opinion 2012-26: m-Qube, Inc., ArmourMedia, Inc. and Cooper for Congress Committee. Management and Administrative Matters. Individuals who plan to attend and require...

  5. 76 FR 42684 - Pacific Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... project team working meeting is to consider the scope of action for the 2013-14 harvest specifications and... groundfish project team responsible for drafting and analyzing the 2013-14 harvest specification and management measures for the Pacific Fishery Management Council (Council) will hold a working meeting, which...

  6. 77 FR 46952 - Approval and Promulgation of Air Quality Implementation Plans; Wisconsin; Regional Haze

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-07

    ... ``its Draft Economic Incentives Program Guidance is relevant to this rulemaking.'' Sierra Club states... Economic Incentive Program Guidance and in program-specific guidance that more directly addresses specific... Economic Incentives Program Guidance. Comment: Sierra Club comments that, ``the emission limits proposed by...

  7. 75 FR 5630 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ... specific parts of the NRC's regulations, techniques that the staff uses in evaluating specific problems or postulated accidents, and data that the staff needs in its review of applications for permits and licenses... in license applications and for monitoring and reporting effluent data by licensees. The guidance is...

  8. Contracting for Audit Services.

    ERIC Educational Resources Information Center

    Heifetz, Harry S.

    1987-01-01

    The Single Audit Act of 1984 requires most school districts receiving over $25,000 in federal funds to undergo financial audits. This article highlights requirements for selecting certified public accountants to perform the audit and suggests factors to be considered before drafting a contract or letter of engagement. A sample letter is included.…

  9. 21 CFR 211.160 - General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 4 2011-04-01 2011-04-01 false General requirements. 211.160 Section 211.160 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... drafted by the appropriate organizational unit and reviewed and approved by the quality control unit. The...

  10. 36 CFR 1236.22 - What are the additional requirements for managing electronic mail records?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... requirements for managing electronic mail records? 1236.22 Section 1236.22 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT ELECTRONIC RECORDS MANAGEMENT Additional... accordance with the provisions of GRS 23, Item 5. (5) Draft documents that are circulated on electronic mail...

  11. 36 CFR 1236.22 - What are the additional requirements for managing electronic mail records?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... requirements for managing electronic mail records? 1236.22 Section 1236.22 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT ELECTRONIC RECORDS MANAGEMENT Additional... accordance with the provisions of GRS 23, Item 5. (5) Draft documents that are circulated on electronic mail...

  12. 36 CFR 1236.22 - What are the additional requirements for managing electronic mail records?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... requirements for managing electronic mail records? 1236.22 Section 1236.22 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT ELECTRONIC RECORDS MANAGEMENT Additional... accordance with the provisions of GRS 23, Item 5. (5) Draft documents that are circulated on electronic mail...

  13. 36 CFR 1236.22 - What are the additional requirements for managing electronic mail records?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... requirements for managing electronic mail records? 1236.22 Section 1236.22 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT ELECTRONIC RECORDS MANAGEMENT Additional... accordance with the provisions of GRS 23, Item 5. (5) Draft documents that are circulated on electronic mail...

  14. 75 FR 51027 - Commission Information Collection Activities (FERC-917 and FERC-918) 1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... public utilities, working through the North American Electric Reliability Corporation (NERC), to develop... required a NERC/NAESB \\3\\ team to draft and review Order No. 890 reliability standards and business... revise reliability standards to require the exchange of data and coordination among transmission...

  15. 78 FR 310 - Draft Revision of Guidance for Industry on Providing Regulatory Submissions in Electronic Format...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-03

    ...ApprovalProcess/FormsSubmissionRequirements/ElectronicSubmissions/ucm253101.htm , http://www.regulations.../Drugs/DevelopmentApprovalProcess/FormsSubmissionRequirements/ElectronicSubmissions/ucm253101.htm , http...), in a format that FDA can process, review, and archive. Currently, the Agency can process, review, and...

  16. 78 FR 33144 - Meeting: RTCA Program Management Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ... by SC-227. Final Draft, New Document, Operational and Functional Requirements and Safety Objectives... & Synthetic Vision Systems-- Discussion--Revised Terms of Reference. SC-214--Standards for Air Traffic Data...

  17. CFD based draft tube hydraulic design optimization

    NASA Astrophysics Data System (ADS)

    McNabb, J.; Devals, C.; Kyriacou, S. A.; Murry, N.; Mullins, B. F.

    2014-03-01

    The draft tube design of a hydraulic turbine, particularly in low to medium head applications, plays an important role in determining the efficiency and power characteristics of the overall machine, since an important proportion of the available energy, being in kinetic form leaving the runner, needs to be recovered by the draft tube into static head. For large units, these efficiency and power characteristics can equate to large sums of money when considering the anticipated selling price of the energy produced over the machine's life-cycle. This same draft tube design is also a key factor in determining the overall civil costs of the powerhouse, primarily in excavation and concreting, which can amount to similar orders of magnitude as the price of the energy produced. Therefore, there is a need to find the optimum compromise between these two conflicting requirements. In this paper, an elaborate approach is described for dealing with this optimization problem. First, the draft tube's detailed geometry is defined as a function of a comprehensive set of design parameters (about 20 of which a subset is allowed to vary during the optimization process) and are then used in a non-uniform rational B-spline based geometric modeller to fully define the wetted surfaces geometry. Since the performance of the draft tube is largely governed by 3D viscous effects, such as boundary layer separation from the walls and swirling flow characteristics, which in turn governs the portion of the available kinetic energy which will be converted into pressure, a full 3D meshing and Navier-Stokes analysis is performed for each design. What makes this even more challenging is the fact that the inlet velocity distribution to the draft tube is governed by the runner at each of the various operating conditions that are of interest for the exploitation of the powerhouse. In order to determine these inlet conditions, a combined steady-state runner and an initial draft tube analysis, using a stage interface between them, must first be performed for each operating condition. Due to the computationally intensive nature of the evaluation process, the efficiency of the optimization algorithm becomes important. Therefore, a state-of-the-art hierarchical-metamodel-assisted evolutionary algorithm is used.

  18. Improved motors for utility applications: Volume 6, Squirrel-cage rotor analysis: Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Griffith, J.W.; McCoy, R.M.

    1986-11-01

    An analysis of squirrel cage induction motor rotors was undertaken in response to an Industry Assessment Study finding 10% of motor failures to be rotor related. The analysis focuses on evaluating rotor design life. The evaluation combines state-of-the-art electromagnetic, thermal, and structural solution techniques into an integrated analysis and presents a simple summary. Finite element techniques are central tools in the analysis. The analysis is applied to a specific forced draft fan drive design. Fans as a category of application have a higher failure rate than other categories of power station auxiliary motor applications. Forced-draft fan drives are one ofmore » the major fan drives which accelerate a relatively high value of rotor load inertia. Various starting and operating conditions are studied for this forced-draft fan drive motor including a representative application duty cycle.« less

  19. High-quality draft genome sequence of Ensifer meliloti Mlalz-1, a microsymbiont of Medicago laciniata (L.) miller collected in Lanzarote, Canary Islands, Spain

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Osman, Wan Adnawani Meor; van Berkum, Peter; León-Barrios, Milagros

    Ensifer meliloti Mlalz-1 (INSDC = ATZD00000000) is an aerobic, motile, Gram-negative, non-spore-forming rod that was isolated from an effective nitrogen-fixing nodule of Medicago laciniata (L.) Miller from a soil sample collected near the town of Guatiza on the island of Lanzarote, the Canary Islands, Spain. This strain nodulates and forms an effective symbiosis with the highly specific host M. laciniata. This rhizobial genome was sequenced as part of the DOE Joint Genome Institute 2010 Genomic Encyclopedia for Bacteria and Archaea-Root Nodule Bacteria (GEBA-RNB) sequencing project. Here in this paper, the features of E. meliloti Mlalz-1 are described, together with high-qualitymore » permanent draft genome sequence information and annotation. The 6,664,116 bp high-quality draft genome is arranged in 99 scaffolds of 100 contigs, containing 6314 protein-coding genes and 74 RNA-only encoding genes. Strain Mlalz-1 is closely related to Ensifer meliloti IAM 12611 T, Ensifer medicae A 321T and Ensifer numidicus ORS 1407 T, based on 16S rRNA gene sequences. gANI values of ≥98.1% support the classification of strain Mlalz-1 as E. meliloti . Nodulation of M. laciniata requires a specific nodC allele, and the nodC gene of strain Mlalz-1 shares ≥98% sequence identity with nodC of M. laciniata-nodulating Ensifer strains, but ≤93% with nodC of Ensifer strains that nodulate other Medicago species. Strain Mlalz-1 is unique among sequenced E. meliloti strains in possessing genes encoding components of a T2SS and in having two versions of the adaptive acid tolerance response lpiA-acvB operon. In E. medicae strain WSM419, lpiA is essential for enhancing survival in lethal acid conditions. The second copy of the lpiA-acvB operon of strain Mlalz-1 has highest sequence identity (> 96%) with that of E. medicae strains, which suggests genetic recombination between strain Mlalz-1 and E. medicae and the horizontal gene transfer of lpiA-acvB.« less

  20. High-quality draft genome sequence of Ensifer meliloti Mlalz-1, a microsymbiont of Medicago laciniata (L.) miller collected in Lanzarote, Canary Islands, Spain

    DOE PAGES

    Osman, Wan Adnawani Meor; van Berkum, Peter; León-Barrios, Milagros; ...

    2017-09-25

    Ensifer meliloti Mlalz-1 (INSDC = ATZD00000000) is an aerobic, motile, Gram-negative, non-spore-forming rod that was isolated from an effective nitrogen-fixing nodule of Medicago laciniata (L.) Miller from a soil sample collected near the town of Guatiza on the island of Lanzarote, the Canary Islands, Spain. This strain nodulates and forms an effective symbiosis with the highly specific host M. laciniata. This rhizobial genome was sequenced as part of the DOE Joint Genome Institute 2010 Genomic Encyclopedia for Bacteria and Archaea-Root Nodule Bacteria (GEBA-RNB) sequencing project. Here in this paper, the features of E. meliloti Mlalz-1 are described, together with high-qualitymore » permanent draft genome sequence information and annotation. The 6,664,116 bp high-quality draft genome is arranged in 99 scaffolds of 100 contigs, containing 6314 protein-coding genes and 74 RNA-only encoding genes. Strain Mlalz-1 is closely related to Ensifer meliloti IAM 12611 T, Ensifer medicae A 321T and Ensifer numidicus ORS 1407 T, based on 16S rRNA gene sequences. gANI values of ≥98.1% support the classification of strain Mlalz-1 as E. meliloti . Nodulation of M. laciniata requires a specific nodC allele, and the nodC gene of strain Mlalz-1 shares ≥98% sequence identity with nodC of M. laciniata-nodulating Ensifer strains, but ≤93% with nodC of Ensifer strains that nodulate other Medicago species. Strain Mlalz-1 is unique among sequenced E. meliloti strains in possessing genes encoding components of a T2SS and in having two versions of the adaptive acid tolerance response lpiA-acvB operon. In E. medicae strain WSM419, lpiA is essential for enhancing survival in lethal acid conditions. The second copy of the lpiA-acvB operon of strain Mlalz-1 has highest sequence identity (> 96%) with that of E. medicae strains, which suggests genetic recombination between strain Mlalz-1 and E. medicae and the horizontal gene transfer of lpiA-acvB.« less

  1. Draft Clinton health reform proposal is circulated as alternatives surface.

    PubMed

    1993-09-20

    A brief summary is provided of the Clinton draft health reform proposal (a 240-page draft outline) that predated the presidential address before Congress on September 22, 1993, and the complete health reform plan. Hillary Rodham Clinton will present a statement before the Senate Finance Committee and the Labor and Human Resources Committee on September 28, as the chairperson of the President's Task Force on Health Care Reform. Top policy aide Ira Magaziner believes that a coalition of moderate Republicans, liberal Democrats, and moderate Democrats will be to pass the bill. Observers see the battle as one of the most difficult for the Clinton administration. The outlined plan would require employers to pay about 80% of health insurance coverage for their employees, including part-time workers and their dependents. Families would pay the remaining 20%. All individuals would be covered, and special subsidies would be available for those under a specified income threshold. Regional health alliances would mediate between consumer and health plans. Premiums would be paid to the alliances, which would have a discrete geographic territory. Alliances would negotiate with health insurance companies for the best care at the lowest prices. Preexisting medical conditions would not prevent coverage. A standard benefit package would be provided and there would be comparability across plans. For instance, covered care would include hospital care, physician and health professional services, clinical preventive services, mental health and substance abuse, family planning services, pregnancy-related services, and drugs. Prevention coverage would include prenatal and well-baby care and routine physical examinations, and reproductive health service procedures such as mammogram and pelvic examinations. Family planning and pregnancy-related services were not defined, and although contraceptive pills would be covered as prescriptions, it is unclear whether diaphragms or IUDs would be covered. Cost-sharing requirements were not specified. In vitro fertilization would not be covered and abortion services are not mentioned specifically. Congressional concern was raised over financing, and over 100 Democrats have supported a single payer, Canadian-style system. Other plans have been proposed. Experience says that congressional input will be necessary before passage.

  2. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (Etbe) ...

    EPA Pesticide Factsheets

    In August 2013, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for ETBE to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in comments on the following: Draft literature search strategies The approach for identifying studies The screening process for selecting pertinent studies The resulting list of pertinent studies Preliminary evidence tables The process for selecting studies to include in evidence tables The quality of the studies in the evidence tables The literature search strategy, which describes the processes for identifying scientific literature, contains the studies that EPA considered and selected to include in the evidence tables. The preliminary evidence tables and exposure-response arrays present the key study data in a standardized format. The evidence tables summarize the available critical scientific literature. The exposure-response figures provide a graphical representation of the responses at different levels of exposure for each study in the evidence table. The draft Toxicological Review of Ethyl Tertiary Butyl Ether provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to ethyl tertiary butyl ether.

  3. [The federal participation law : New requirements for needs assessment with special emphasis on medical rehabilitation services].

    PubMed

    Schubert, Michael; Schian, Marcus; Viehmeier, Sarah

    2016-09-01

    The federal participation law (Bundesteilhabegesetz - BTHG) is one of the largest efforts in the last 15 years to reform the legal participation rights of people with disabilities. In particular, a number of enhancements are planned in the overall benefits law in Part 1 of Book IX in the Social Code (Sozialgesetzbuch - SGB), which applies to all rehabilitation carriers including general provisions and standards for needs assessment. This paper deals with the implications of these provisions and interacting standards, based on the draft bill of April 2016.The discussion takes place against the background of the regulatory objectives formulated in the ministerial draft itself, jurisprudential expertise on the effects of the current legal norms of the SGB IX as well as relevant professional political developments and statements by various stakeholders.The analysis shows a clear political commitment to increase the requirements for needs assessment in the overall law of the SGB IX and to express these more effectively. The draft bill seeks not only to modify procedures subsequent to the application for rehabilitation benefits, but also to precisely set out provisions on instruments for needs assessment in a new § 13. Common principles for these instruments of needs assessment should increase the cooperation, coordination and convergence among rehabilitation carriers.Nevertheless, with regard to the proposed regulatory texts, there is doubt that the objectives set by the draft bill itself will be achieved. For example, the required common principles for needs assessment are to be agreed upon based on the existing special legislation for the different rehabilitation carriers, without the SGB IX setting its own binding standards or framework principles. In addition, it lacks clear legal guidelines for the professional practice to make use of the bio-psycho-social model of the WHO and the ICF in the process of needs assessment. As a consequence the ICF cannot serve as a legally standardized reference point.

  4. ESA Human rating Requirements:Status

    NASA Astrophysics Data System (ADS)

    Trujillo, M.; Sgobba, T.

    2012-01-01

    The European Space Agency (ESA) human rating safety requirements are based on heritage requirements of the International Space Station as well as the knowledge and experience derived from European participation on international partnerships. This expertise in conjunction with recommendations derived from past accidents (i.e.: Columbia) and lessons learned have led to the identification of m inimum core safety tech nical requirements for hum an rated space syst ems. These requirements apply to th e crewed space vehicle, integrated space system (i.e.: cre wed vehicle on its launcher) and its interfaces with control centres, la unch pad, etc. In 2009, a first draft was issued. Then, in the summer of 2010, ESA established a working group comprised of more than twenty experts (from disciplines including propulsion, pyrotechnics, structures, avionics, human factors and life support among others) across the Agency to review this draft. This paper provides an overview of ESA "Safety technical re quirements for human rated s pace systems" document, its scope a nd structure, as well as the planned steps for verification of these requirements in term s of achieving the identified safety objectives for crew safety in t erms of a quantitative risk evaluation.

  5. Main Ingredients for Success in L2 Academic Writing: Outlining, Drafting and Proofreading.

    PubMed

    Munoz-Luna, Rosa

    2015-01-01

    Spanish undergraduates of English Studies are required to submit their essays in academic English, a genre which most of them are not acquainted with. This paper aims to explore the extralinguistic side of second language (L2) academic writing, more specifically, the combination of metalinguistic items (e.g. transition and frame markers, among others) with students' writing strategies when composing an academic text in L2 English. The research sample conveys a group of 200 Spanish undergraduates of English Studies; they are in their fourth year, so they are expected to be proficient in English academic writing but their written production quality varies considerably. Results are analysed following a mixed methodology by which metalinguistic items are statistically measured, and then contrasted with semi-structured interview results; SPSS and NVivo provide quantitative and qualitative outcomes, respectively. The analyses reveal that undergraduate students who produce complex sentences and more coherent texts employ a wider range of writing strategies both prior and while writing, being able to (un)consciously structure and design their texts more successfully. These high-scoring students make more proficient use of complex transition markers for coherence and frame markers for textual cohesion; their commonly used (pre-)writing strategies are drafting, outlining, and proofreading.

  6. The need for transparency and reproducibility in documenting values for regulatory decision making and evaluating causality: The example of formaldehyde.

    PubMed

    Van Landingham, Cynthia; Mundt, Kenneth A; Allen, Bruce C; Gentry, P Robinan

    2016-11-01

    Reproducibility and transparency in scientific reporting is paramount to advancing science and providing the foundation required for sound regulation. Recent examples demonstrate that pivotal scientific findings cannot be replicated, due to poor documentation or methodological bias, sparking debate across scientific and regulatory communities. However, there is general agreement that improvements in communicating and documenting research and risk assessment methods are needed. In the case of formaldehyde, the peer-review conducted by a National Academy of Sciences (NAS) Committee questioned the approaches used by the Integrated Risk Information System (IRIS) in developing draft unit risk values. Using the original data from the key study (Beane Freeman et al., 2009) and documentation provided in the draft IRIS profile, we attempted to duplicate the reported inhalation unit risk values and address the NAS Committee's questions regarding application of the appropriate dose-response model. Overall, documentation of the methods lacked sufficient detail to allow for replication of the unit risk estimates, specifically for Hodgkin lymphoma and leukemias, the key systemic endpoints selected by IRIS. The lack of apparent exposure-response relationships for selected endpoints raises the question whether quantitative analyses are appropriate for these endpoints, and if so, how results are to be interpreted. Copyright © 2016. Published by Elsevier Inc.

  7. Main Ingredients for Success in L2 Academic Writing: Outlining, Drafting and Proofreading

    PubMed Central

    Munoz-Luna, Rosa

    2015-01-01

    Spanish undergraduates of English Studies are required to submit their essays in academic English, a genre which most of them are not acquainted with. This paper aims to explore the extralinguistic side of second language (L2) academic writing, more specifically, the combination of metalinguistic items (e.g. transition and frame markers, among others) with students’ writing strategies when composing an academic text in L2 English. The research sample conveys a group of 200 Spanish undergraduates of English Studies; they are in their fourth year, so they are expected to be proficient in English academic writing but their written production quality varies considerably. Results are analysed following a mixed methodology by which metalinguistic items are statistically measured, and then contrasted with semi-structured interview results; SPSS and NVivo provide quantitative and qualitative outcomes, respectively. The analyses reveal that undergraduate students who produce complex sentences and more coherent texts employ a wider range of writing strategies both prior and while writing, being able to (un)consciously structure and design their texts more successfully. These high-scoring students make more proficient use of complex transition markers for coherence and frame markers for textual cohesion; their commonly used (pre-)writing strategies are drafting, outlining, and proofreading. PMID:26046836

  8. Predicting Backdrafting and Spillage for Natural-Draft Gas Combustion Appliances: Validating VENT-II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rapp, Vi H.; Pastor-Perez, Albert; Singer, Brett C.

    2013-04-01

    VENT-II is a computer program designed to provide detailed analysis of natural draft and induced draft combustion appliance vent-systems (i.e., furnace or water heater). This program is capable of predicting house depressurization thresholds that lead to backdrafting and spillage of combustion appliances; however, validation reports of the program being applied for this purpose are not readily available. The purpose of this report is to assess VENT-II’s ability to predict combustion gas spillage events due to house depressurization by comparing VENT-II simulated results with experimental data for four appliance configurations. The results show that VENT-II correctly predicts depressurizations resulting in spillagemore » for natural draft appliances operating in cold and mild outdoor conditions, but not for hot conditions. In the latter case, the predicted depressurizations depend on whether the vent section is defined as part of the vent connector or the common vent when setting up the model. Overall, the VENTII solver requires further investigation before it can be used reliably to predict spillage caused by depressurization over a full year of weather conditions, especially where hot conditions occur.« less

  9. SSPACE-LongRead: scaffolding bacterial draft genomes using long read sequence information

    PubMed Central

    2014-01-01

    Background The recent introduction of the Pacific Biosciences RS single molecule sequencing technology has opened new doors to scaffolding genome assemblies in a cost-effective manner. The long read sequence information is promised to enhance the quality of incomplete and inaccurate draft assemblies constructed from Next Generation Sequencing (NGS) data. Results Here we propose a novel hybrid assembly methodology that aims to scaffold pre-assembled contigs in an iterative manner using PacBio RS long read information as a backbone. On a test set comprising six bacterial draft genomes, assembled using either a single Illumina MiSeq or Roche 454 library, we show that even a 50× coverage of uncorrected PacBio RS long reads is sufficient to drastically reduce the number of contigs. Comparisons to the AHA scaffolder indicate our strategy is better capable of producing (nearly) complete bacterial genomes. Conclusions The current work describes our SSPACE-LongRead software which is designed to upgrade incomplete draft genomes using single molecule sequences. We conclude that the recent advances of the PacBio sequencing technology and chemistry, in combination with the limited computational resources required to run our program, allow to scaffold genomes in a fast and reliable manner. PMID:24950923

  10. 78 FR 53791 - Draft Program-Specific Guidance About Irradiator Licenses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... CONTACT: Tomas Herrera, Office of Federal and State Materials and Environmental Management Programs; U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001; telephone: 301-415- 7138; email: Tomas.Herrera...

  11. Cloning, functional expression and characterization of a bifunctional 3-hydroxybutanal dehydrogenase /reductase involved in acetone metabolism by Desulfococcus biacutus.

    PubMed

    Frey, Jasmin; Rusche, Hendrik; Schink, Bernhard; Schleheck, David

    2016-11-25

    The strictly anaerobic, sulfate-reducing bacterium Desulfococcus biacutus can utilize acetone as sole carbon and energy source for growth. Whereas in aerobic and nitrate-reducing bacteria acetone is activated by carboxylation with CO 2 to acetoacetate, D. biacutus involves CO as a cosubstrate for acetone activation through a different, so far unknown pathway. Proteomic studies indicated that, among others, a predicted medium-chain dehydrogenase/reductase (MDR) superfamily, zinc-dependent alcohol dehydrogenase (locus tag DebiaDRAFT_04514) is specifically and highly produced during growth with acetone. The MDR gene DebiaDRAFT_04514 was cloned and overexpressed in E. coli. The purified recombinant protein required zinc as cofactor, and accepted NADH/NAD + but not NADPH/NADP + as electron donor/acceptor. The pH optimum was at pH 8, and the temperature optimum at 45 °C. Highest specific activities were observed for reduction of C 3 - C 5 -aldehydes with NADH, such as propanal to propanol (380 ± 15 mU mg -1 protein), butanal to butanol (300 ± 24 mU mg -1 ), and 3-hydroxybutanal to 1,3-butanediol (248 ± 60 mU mg -1 ), however, the enzyme also oxidized 3-hydroxybutanal with NAD + to acetoacetaldehyde (83 ± 18 mU mg -1 ). The enzyme might play a key role in acetone degradation by D. biacutus, for example as a bifunctional 3-hydroxybutanal dehydrogenase/reductase. Its recombinant production may represent an important step in the elucidation of the complete degradation pathway.

  12. 76 FR 52958 - Draft Guidance for Industry on Neglected Tropical Diseases of the Developing World: Developing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ...The Food and Drug Administration (FDA) is announcing the availability of a draft guidance for industry entitled ``Neglected Tropical Diseases of the Developing World: Developing Drugs for Treatment or Prevention.'' The purpose of this guidance is to assist sponsors in the clinical development of drugs for the treatment or prevention of neglected diseases of the developing world. Specifically, this guidance addresses FDA's current thinking regarding the overall drug development program for the treatment or prevention of neglected tropical diseases (NTDs), including clinical trial designs and internal review standards to support approval of drugs.

  13. Mission Operations and Information Management Area Spacecraft Monitoring and Control Working Group

    NASA Technical Reports Server (NTRS)

    Lokerson, Donald C. (Editor)

    2005-01-01

    Working group goals for this year are: Goal 1. Due to many review comments the green books will be updated and available for re-review by CCSDS. Submission of green books to CCSDS for approval. Goal 2.Initial set of 4 new drafts of the red books as following: SM&C protocol: update with received comments. SM&C common services: update with received comments and expand the service specification. SM&C core services: update with received comments and expand the service the information model. SM&C time services: (target objective): produce initial draft following template of core services.

  14. Draft genome sequence of Bradyrhizobium paxllaeri LMTR 21T isolated from Lima bean (Phaseolus lunatus) in Peru.

    PubMed

    Ormeño-Orrillo, Ernesto; Rey, Luis; Durán, David; Canchaya, Carlos A; Rogel, Marco A; Zúñiga-Dávila, Doris; Imperial, Juan; Ruiz-Argüeso, Tomás; Martínez-Romero, Esperanza

    2017-09-01

    Bradyrhizobium paxllaeri is a prevalent species in root nodules of the Lima bean ( Phaseolus lunatus ) in Peru. LMTR 21 T is the type strain of the species and was isolated from a root nodule collected in an agricultural field in the Peruvian central coast. Its 8.29 Mbp genome encoded 7635 CDS, 71 tRNAs and 3 rRNAs genes. All genes required to stablish a nitrogen-fixing symbiosis with its host were present. The draft genome sequence and annotation have been deposited at GenBank under the accession number MAXB00000000.

  15. 75 FR 13269 - Environmental Management Site-Specific Advisory Board, Hanford

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    .... ADDRESSES: Red Lion Hotel on the River, Jantzen Beach, 909 North Hayden Island Drive, Portland, OR 97217... Protection Committee; Public Involvement Committee; and Budgets and Contracts Committee Draft Advice on Long...

  16. 77 FR 30050 - VASRD Status Summit: A Public Overview of Proposed Disability Evaluation Criteria

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ... body system, Rheumatic Diseases. Specifically, working drafts containing proposed revisions to...) Infectious Diseases, Immune Disorders and Nutritional Deficiencies (38 CFR 4.88-4.89), (5) The...

  17. A study of electro-mechanical and infrastructure instrumentation facilities in environmental laboratory.

    PubMed

    Dhawangale, R M; Kawale, S M; Waghmare, Maya; Pandya, G H; Kondawar, V K

    2006-01-01

    Environmental laboratories carry out measurement and analysis of a number of physical, chemical and biological parameters. Each parameter requires some sort of instrument for its determination. Providing efficient instrumentation services to various departments of the Institute is an stupendous task. Instrumentation services in the form of installation, operation, repair and maintenanace of electro-mechanical equipment requires an in-depth experience and knowledge of the working, fabrication, design and repair of similar type of instruments so that the need of space, installation pre-requisites, budget constraints, availability of essential spares parts could be assessed. The paper discusses the operation of an environmental instrument repairs and maintenance, and audio-visual facilities. Suggestions for drafting of the proper specifications for procurement of laboratory equipments, such as ovens, furnaces, refrigerators, blowers, audio visual aids, and spares and accessories are given in this paper. The paper also gives the detailed information on various aspects that are needed for checking and testing of the equipment against specification before putting it in operational use. Development of a preventive maintenance program involving QC checks and keeping an inventory of essential spares required are also discussed in this paper. It is felt that such services are essential in providing smooth support to carry out research and development activities of the Institute.

  18. 14 CFR 1216.308 - Preparation of draft statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... consultation requirements of the Endangered Species Act of 1973, as amended, should be met prior to or through... Procedures for Implementing the National Environmental Policy Act (NEPA) Agency Procedures § 1216.308...

  19. 14 CFR 1216.308 - Preparation of draft statements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... consultation requirements of the Endangered Species Act of 1973, as amended, should be met prior to or through... Procedures for Implementing the National Environmental Policy Act (NEPA) Agency Procedures § 1216.308...

  20. Camp Minden Draft QASP and Work Plan for Public Feedback

    EPA Pesticide Factsheets

    ESI has developed these operational plans, technical approaches, and related required resources based upon extensive review and planning for material removal, transportation, staging, and Contained Burn Chamber (CBC) destruction of materials.

  1. Security Analysis of DTN Architecture and Bundle Protocol Specification for Space-Based Networks

    NASA Technical Reports Server (NTRS)

    Ivancic, William D.

    2009-01-01

    A Delay-Tolerant Network (DTN) Architecture (Request for Comment, RFC-4838) and Bundle Protocol Specification, RFC-5050, have been proposed for space and terrestrial networks. Additional security specifications have been provided via the Bundle Security Specification (currently a work in progress as an Internet Research Task Force internet-draft) and, for link-layer protocols applicable to Space networks, the Licklider Transport Protocol Security Extensions. This document provides a security analysis of the current DTN RFCs and proposed security related internet drafts with a focus on space-based communication networks, which is a rather restricted subset of DTN networks. Note, the original focus and motivation of DTN work was for the Interplanetary Internet . This document does not address general store-and-forward network overlays, just the current work being done by the Internet Research Task Force (IRTF) and the Consultative Committee for Space Data Systems (CCSDS) Space Internetworking Services Area (SIS) - DTN working group under the DTN and Bundle umbrellas. However, much of the analysis is relevant to general store-and-forward overlays.

  2. Resource Programs : Draft Environmental Impact Statement, Volume 2, Appendices.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    United States. Bonneville Power Administration.

    1992-03-01

    Every two years, Bonneville Power Administration (BPA) prepares a Resource Program which identifies the resource actions BPA will take to meet its obligation to serve the forecasted power requirements of its customers. The Resource Program`s Environmental Impact Statement (RPEIS) is a programmatic environmental document which will support decisions made in several future Resource Programs. Environmental documents tiered to the EIS may be prepared on a site-specific basis. The RPEIS includes a description of the environmental effects and mitigation for the various resource types available in order to evaluate the trade-offs among them. It also assesses the environmental impacts of addingmore » thirteen alternative combinations of resources to the existing power system. This report contains the appendices to the RPEIS.« less

  3. United Kingdom unveils ambitious air pollution plan

    NASA Astrophysics Data System (ADS)

    Warren, Matthew

    2018-06-01

    The U.K. government's new strategy to combat air pollution has drawn praise for its ambitious goals—and reservations about whether they will be achieved. Environmental scientists have applauded the aims of the Clean Air Strategy, which include substantially reducing the number of people breathing air containing high levels of fine particulates and curbing ammonia emissions from agriculture. But for now, the document, published as a draft for public consultation on 22 May, remains light on the specific policies that will help the country attain these goals. And although the government has said that with the new strategy it will go further than the European Union in tackling air pollution post-Brexit, scientists say major improvements to air quality will require a coordinated effort across Europe.

  4. An empirical definition of clinical supervision.

    PubMed

    Milne, Derek

    2007-11-01

    The growing recognition of clinical supervision as the basis for high-quality mental health services is apparent in policy, research and clinical practice, but an empirical definition is required to progress research and practice. A logical analysis was used to draft a working definition, and then a systematic review of 24 empirical studies of clinical supervision produced a best evidence synthesis, which was used to test and improve this definition. The logical analysis indicated that the most popular definition (Bernard & Goodyear, 1992) failed all four necessary tests of a good definition: precision, specification, operationalization and corroboration. The systematic review synthesis was then used to test the working definition, which passed these tests (with two amendments). These two complementary review approaches created a firmer basis for advancing research and practice.

  5. 14 CFR 1216.320 - Environmental review and consultation requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., assessments, and any impact statement preparation concurrently with environmental reviews required by the laws... properties which may be eligible for the National Register within the area of the potential impact of a NASA proposed action. Evaluation of the impact of the NASA action on such properties shall be discussed in draft...

  6. 14 CFR 1216.320 - Environmental review and consultation requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., assessments, and any impact statement preparation concurrently with environmental reviews required by the laws... properties which may be eligible for the National Register within the area of the potential impact of a NASA proposed action. Evaluation of the impact of the NASA action on such properties shall be discussed in draft...

  7. 14 CFR 1216.320 - Environmental review and consultation requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., assessments, and any impact statement preparation concurrently with environmental reviews required by the laws... properties which may be eligible for the National Register within the area of the potential impact of a NASA proposed action. Evaluation of the impact of the NASA action on such properties shall be discussed in draft...

  8. C2 Link Security for UAS: Technical Literature Study and Preliminary Functional Requirements. Version 0.9 (Working Draft)

    NASA Technical Reports Server (NTRS)

    2005-01-01

    This document provides a study of the technical literature related to Command and Control (C2) link security for Unmanned Aircraft Systems (UAS) for operation in the National Airspace System (NAS). Included is a preliminary set of functional requirements for C2 link security.

  9. 76 FR 40921 - Draft Guidance for Industry and Food and Drug Administration Staff; Enforcement Policy for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-12

    ... regard to enforcement of premarket notification (510(k)) requirements for certain in vitro diagnostic and... devices that have established safety and effectiveness profiles and for which it believes 510(k) review is... 510(k) requirement through rulemaking that would reclassify the Class II devices and amend the...

  10. 40 CFR 265.147 - Liability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... pursuant to a draft by the trustee of the standby trust will be deposited by the issuing institution into... this section. (5) An owner or operator may meet the requirements of this section by obtaining a trust..., guarantee, letter of credit, surety bond, and trust fund, except that the owner or operator may not combine...

  11. 40 CFR 264.147 - Liability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... pursuant to a draft by the trustee of the standby trust will be deposited by the issuing institution into... operator may meet the requirements of this section by obtaining a trust fund for liability coverage as... bond, and trust fund, except that the owner or operator may not combine a financial test covering part...

  12. 40 CFR 45.150 - Reports.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Reports. 45.150 Section 45.150... ASSISTANCE § 45.150 Reports. (a) Recipients must submit the reports required in 40 CFR 30.505. (b) A draft of the final project report is required 90 days before the end of the project period. The recipient shall...

  13. 40 CFR 45.150 - Reports.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Reports. 45.150 Section 45.150... ASSISTANCE § 45.150 Reports. (a) Recipients must submit the reports required in 40 CFR 30.505. (b) A draft of the final project report is required 90 days before the end of the project period. The recipient shall...

  14. IRIS Toxicological Review of Tert-Butyl Alcohol (Tert-Butanol) ...

    EPA Pesticide Factsheets

    On April 29, 2016, the Toxicological Review of tert-Butyl Alcohol (tert-Butanol) (Public Comment Draft) was released for public comment. The draft Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and the Executive Office of the President during Step 3 (Interagency Science Consultation) before public release. As part of the IRIS process, all written interagency comments on IRIS assessments will be made publicly available. Accordingly, interagency comments with EPA's response and the interagency science consultation drafts of the IRIS Toxicological Review of tert-Butanol and charge to external peer reviewers are posted on this site. EPA is undertaking a new health assessment for t-butyl alcohol (tert-butanol) for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS and IRIS Summary of TBA that will be entered on the IRIS database. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information to evaluate potential public health risks associated with environmental contaminants. The IRIS database is relied on for the development of risk assessments, site-specific environmental decisions, and rule making.

  15. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (Etbe) ...

    EPA Pesticide Factsheets

    In September 2016, EPA released the draft IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) for public comment and discussion. The draft assessment was reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science consultation materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Ethyl Tertiary Butyl Ether are posted on this site. EPA is undertaking an new health assessment for ethyl tertiary butyl ether (ETBE) for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS Summary of ETBE that will be entered on the IRIS database. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment process, i.e., hazard identification and dose-response evaluation. IRIS assessments are used nationally and internationally in combination with specific situational exposure assessment infor

  16. Analysis of UAS DAA Alerting in Fast-Time Simulations without DAA Mitigation

    NASA Technical Reports Server (NTRS)

    Thipphavong, David P.; Santiago, Confesor; Isaacson, Douglas R.; Lee, Seung Man; Park, Chunki; Refai, Mohamad Said; Snow, James

    2015-01-01

    Realization of the expected proliferation of Unmanned Aircraft System (UAS) operations in the National Airspace System (NAS) depends on the development and validation of performance standards for UAS Detect and Avoid (DAA) Systems. The RTCA Special Committee 228 is charged with leading the development of draft Minimum Operational Performance Standards (MOPS) for UAS DAA Systems. NASA, as a participating member of RTCA SC-228 is committed to supporting the development and validation of draft requirements for DAA alerting system performance. A recent study conducted using NASA's ACES (Airspace Concept Evaluation System) simulation capability begins to address questions surrounding the development of draft MOPS for DAA alerting systems. ACES simulations were conducted to study the performance of alerting systems proposed by the SC-228 DAA Alerting sub-group. Analysis included but was not limited to: 1) correct alert (and timeliness), 2) false alert (and severity and duration), 3) missed alert, and 4) probability of an alert type at the time of loss of well clear. The performance of DAA alerting systems when using intent vs. dead-reckoning for UAS ownship trajectories was also compared. The results will be used by SC-228 to inform decisions about the surveillance standards of UAS DAA systems and future requirements development and validation efforts.

  17. Analysis of UAS DAA Surveillance in Fast-Time Simulations without DAA Mitigation

    NASA Technical Reports Server (NTRS)

    Thipphavong, David P.; Santiago, Confesor; Isaacson, David R.; Lee, Seung Man; Refai, Mohamad Said; Snow, James William

    2015-01-01

    Realization of the expected proliferation of Unmanned Aircraft System (UAS) operations in the National Airspace System (NAS) depends on the development and validation of performance standards for UAS Detect and Avoid (DAA) Systems. The RTCA Special Committee 228 is charged with leading the development of draft Minimum Operational Performance Standards (MOPS) for UAS DAA Systems. NASA, as a participating member of RTCA SC-228 is committed to supporting the development and validation of draft requirements for DAA surveillance system performance. A recent study conducted using NASA's ACES (Airspace Concept Evaluation System) simulation capability begins to address questions surrounding the development of draft MOPS for DAA surveillance systems. ACES simulations were conducted to study the performance of sensor systems proposed by the SC-228 DAA Surveillance sub-group. Analysis included but was not limited to: 1) number of intruders (both IFR and VFR) detected by all sensors as a function of UAS flight time, 2) number of intruders (both IFR and VFR) detected by radar alone as a function of UAS flight time, and 3) number of VFR intruders detected by all sensors as a function of UAS flight time. The results will be used by SC-228 to inform decisions about the surveillance standards of UAS DAA systems and future requirements development and validation efforts.

  18. 36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

  19. 36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

  20. 36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

  1. 36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

  2. 36 CFR § 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

  3. Alcohol ignition interlock service support

    DOT National Transportation Integrated Search

    1992-12-01

    Author's abstract: This Technical Report was produced under Contract No. DTNH22-89-C-07009 for the National Highway Traffic Safety Administration. Under that same contract, a draft set of model specifications for Breath Alcohol Ignition Interlock Dev...

  4. Draft greenhouse gas emissions from transit projects : programmatic assessment

    DOT National Transportation Integrated Search

    2016-11-01

    The National Environmental Policy Act (NEPA) requires federal agencies to disclose and analyze the environmental effects of their proposed actions. The Federal Transit Administration (FTA) currently believes that assessing the effects of greenhouse g...

  5. Economic Incentive Approaches to Air Pollution Control (1981)

    EPA Pesticide Factsheets

    This draft report was prepared to respond to the requirements of Section 405(g) of the Clean Air Act for a general report on economic incentive approaches to air pollution control, but was never issued.

  6. 22 CFR 65.1 - Regulations to be drafted.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of the other American republics who may be accommodated in each such institution or course at any one time. (c) A statement of the qualifications to be required of students of the other American republics...

  7. 76 FR 66311 - Draft Documents To Support Submission of an Electronic Common Technical Document; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-26

    .../DevelopmentApprovalProcess/FormsSubmissionRequirements/ElectronicSubmissions/ucm253101.htm , http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/default.htm , or http...

  8. Medical devices manufactured from latex: European regulatory initiatives.

    PubMed

    De Jong, W H; Geertsma, R E; Tinkler, J J B

    2002-05-01

    In Europe the marketing of medical devices manufactured from latex is regulated by directives describing the essential (safety) requirements that products have to fulfill to obtain marketing approval. This paper describes the general requirements for marketing medical devices in Europe and, more specifically, the requirements for products manufactured from natural rubber latex. The requirements for marketing medical devices can be fulfilled by using the relevant harmonized European standards. These standards are regularly under revision to incorporate the latest scientific developments. For certain devices, for example, latex medical (examination and surgical) gloves, specific standards have been published. Medical devices manufactured from latex pose a serious problem because of the risk of induction of allergy both against the latex proteins inherently present (type I or immediate type allergy) and against chemicals added during processing (type IV or delayed type hypersensitivity) present as residues in the latex products. So, besides requirements for product quality in terms of barrier properties, strength, and sterility, the main focus consists of the allergy-inducing properties of the latex products. Recent developments have reopened the discussion on the value of total protein versus allergen determination in latex medical gloves. However, as long as minimal levels needed for both sensitization and elicitation have not been established, a safe maximum level for leachable proteins/allergens in latex products cannot be determined. A European Commission guidance document on the latex allergy problem is currently being drafted by experts from Competent Authorities. Copyright 2002 Elsevier Science (USA).

  9. Legal Background of Aviation Medicine in Europe and its future development

    PubMed Central

    Siedenburg, J

    2008-01-01

    European aviation is moving into an exciting phase now, the administrative structure is changing. Aviation rules and aviation medicine will get a new structure as well. The nature of air traffic required an international scope in rulemaking – especially in such a confined continent as Europe with 41 countries, about 380 Million inhabitants and 317 billion person kilometres flown each year. For economic reasons it became necessary to develop common standards for certification of aircraft in the beginning of the 1970ies, maintenance followed later on. The Cyprus arrangement of 01 July 1990 created the JAA (Joint Aviation Authorities). Joint Aviation Requirements were drafted to replace existing national provisions and have been implemented from the end of the 1990ies. The areas of air operations and pilot licensing have been covered as well. The latter comprises of aviation medicine as well. The implementation of JAR-FCL 3, which covers the medical requirements for pilots, started from 1999 on in the several JAA member states. A detailed overview about development and structure of JAA, tools for harmonisation, rulemaking and amendment of requirements, medical standards, review procedures for contentious or marginal cases is described. Shortcomings were the fact that implementation was left to the discretion of the member states and that JAA had no executive power. This resulted in differences in safety and the EU commission concluded that aviation safety had to be regulated by the EU commission. After adoption of EU regulation 1592/2002 in 2002 common and binding requirements were to be drafted and a European aviation agency to be founded. EASA (European Aviation Safety Agency) started its work in September 2003. Finally it will take over the role of JAA completely. Whereas Certification and Maintenance were in the focus first, Flight Operations and Licensing are going to be covered as well in the near future. Essential Requirements have been drafted, outlining – inter alia – the scope of Licensing and of aeromedical aspects. However, the legislative process will most probably last at least until the end of 2007. Implementing Rules - being based on existing JAR-FCLs will be drafted soon and are going to be implemented as soon as EASA is operative for Licensing. JAR-FCL 3 will be the basis for the Implementing Rules concerning aeromedical fitness. An overview about the structure of the Agency, rulemaking procedures, philosophy of medical provisions and the transition from JAA to EASA is described. PMID:19048095

  10. 46 CFR 97.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Draft marks and draft indicating systems. 97.40-10... VESSELS OPERATIONS Markings on Vessels § 97.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  11. 46 CFR 196.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Draft marks and draft indicating systems. 196.40-10... VESSELS OPERATIONS Markings on Vessels § 196.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  12. 46 CFR 78.50-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 3 2013-10-01 2013-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

  13. 46 CFR 97.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Draft marks and draft indicating systems. 97.40-10... VESSELS OPERATIONS Markings on Vessels § 97.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  14. 46 CFR 97.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Draft marks and draft indicating systems. 97.40-10... VESSELS OPERATIONS Markings on Vessels § 97.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  15. 46 CFR 196.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Draft marks and draft indicating systems. 196.40-10... VESSELS OPERATIONS Markings on Vessels § 196.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  16. 46 CFR 97.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Draft marks and draft indicating systems. 97.40-10... VESSELS OPERATIONS Markings on Vessels § 97.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  17. 46 CFR 196.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Draft marks and draft indicating systems. 196.40-10... VESSELS OPERATIONS Markings on Vessels § 196.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  18. 46 CFR 78.50-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

  19. 46 CFR 78.50-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 3 2014-10-01 2014-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

  20. 46 CFR 78.50-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 3 2012-10-01 2012-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

  1. 46 CFR 97.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Draft marks and draft indicating systems. 97.40-10... VESSELS OPERATIONS Markings on Vessels § 97.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  2. 46 CFR 196.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Draft marks and draft indicating systems. 196.40-10... VESSELS OPERATIONS Markings on Vessels § 196.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  3. 46 CFR 78.50-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 3 2011-10-01 2011-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

  4. 46 CFR 196.40-10 - Draft marks and draft indicating systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Draft marks and draft indicating systems. 196.40-10... VESSELS OPERATIONS Markings on Vessels § 196.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

  5. Data Citation Standard: A Means to Support Data Sharing, Attribution, and Traceability

    NASA Astrophysics Data System (ADS)

    McCallum, I.; Plag, H. P.; Fritz, S.

    2012-04-01

    Geo-referenced data are crucial for addressing many of the burning societal problems and to support related interdisciplinary research. Data sharing is hampered by the lack of a widely accepted method for giving credit to those who make their data freely available and for tracking the use of data throughout it's life-cycle. Particularly in the scientific community, recognition and renown are important currencies. Providing means for data citation would be a strong incentive for data sharing. Recently, a number of organizations and projects have started to address the concept of data citation (e.g., PANGAEA, NASA DAACS, USGS, NOAA National Data Centers, ESIP, US National Academy of Sciences, and EGIDA). A number of proposals for data citation guidelines have emerged and a better understanding of the many issues at hand is evolving, but to date, no standard has been accepted. This is not surprising, as data citation is far more complicated than citation of scientific publication. Data sets differ in many aspects from standard scientific publications. For example, data sets generally are not locatable and attributable in the same way as scientific publications. Data sets often are not static (introducing versioning), and they are mostly not peer-reviewed (requiring quality control). There is a consensus that the implementation of a standard would reveal new issues that are not obvious today. With the Global Earth Observation System of Systems (GEOSS), the Group on Earth Observations (GEO) is in a unique position to provide the testbed for the implementation of a draft standard. The GEO Plenary supports the implementation of a draft standard developed by the Science and Technology Committee (STC) of GEO with support of the EGIDA Project. This draft is based on guidelines developed by international groups. Currently, users of the GEO-Portal are not obliged or encouraged to cite data accessed through GEOSS - if at all, citation requirements come from the individual data providers. This naturally leads to a at-best non-standard form of data citation or, in the worst case, no data citation at all. The testbed implementation will rectify this situation and help to identify issues not covered by the standard. The process of implementing and iteratively improving the draft is led by the GEO Work Plan Task ID-03 under the Institutions and Development Board; coordinated with the GEO working groups in charge of developing the GEOSS Common Infrastructure (e.g., the Architecture Board, SIF, DSTF, GCI-CT; with other groups within GEO, such as the Data Sharing Task Force, who have initiated similar activities, and with organizations outside of GEO developing the internationally emerging specifications. Metadata for GEOSS data and products may have to be extended to support data citation. It is expected that the availability of a draft citation standard will increase the attractiveness of GEO and GEOSS for scientists by fostering acknowledgment of their contributions when others use them. The testbed implementation will provide valuable insight into issues that need to be addressed and this will be infused into the international discussion on data citation.

  6. A proposal for amending administrative law to facilitate adaptive management

    NASA Astrophysics Data System (ADS)

    Craig, Robin K.; Ruhl, J. B.; Brown, Eleanor D.; Williams, Byron K.

    2017-07-01

    In this article we examine how federal agencies use adaptive management. In order for federal agencies to implement adaptive management more successfully, administrative law must adapt to adaptive management, and we propose changes in administrative law that will help to steer the current process out of a dead end. Adaptive management is a form of structured decision making that is widely used in natural resources management. It involves specific steps integrated in an iterative process for adjusting management actions as new information becomes available. Theoretical requirements for adaptive management notwithstanding, federal agency decision making is subject to the requirements of the federal Administrative Procedure Act, and state agencies are subject to the states’ parallel statutes. We argue that conventional administrative law has unnecessarily shackled effective use of adaptive management. We show that through a specialized ‘adaptive management track’ of administrative procedures, the core values of administrative law—especially public participation, judicial review, and finality— can be implemented in ways that allow for more effective adaptive management. We present and explain draft model legislation (the Model Adaptive Management Procedure Act) that would create such a track for the specific types of agency decision making that could benefit from adaptive management.

  7. A proposal for amending administrative law to facilitate adaptive management

    USGS Publications Warehouse

    Craig, Robin K.; Ruhl, J.B.; Brown, Eleanor D.; Williams, Byron K.

    2017-01-01

    In this article we examine how federal agencies use adaptive management. In order for federal agencies to implement adaptive management more successfully, administrative law must adapt to adaptive management, and we propose changes in administrative law that will help to steer the current process out of a dead end. Adaptive management is a form of structured decision making that is widely used in natural resources management. It involves specific steps integrated in an iterative process for adjusting management actions as new information becomes available. Theoretical requirements for adaptive management notwithstanding, federal agency decision making is subject to the requirements of the federal Administrative Procedure Act, and state agencies are subject to the states' parallel statutes. We argue that conventional administrative law has unnecessarily shackled effective use of adaptive management. We show that through a specialized 'adaptive management track' of administrative procedures, the core values of administrative law—especially public participation, judicial review, and finality— can be implemented in ways that allow for more effective adaptive management. We present and explain draft model legislation (the Model Adaptive Management Procedure Act) that would create such a track for the specific types of agency decision making that could benefit from adaptive management.

  8. 12 CFR 516.45 - What is the filing date of my application?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the following requirements. (1) You attend a pre-filing meeting and submit a draft business plan or... required number of copies with that office. (iii) If you file after the close of business established by a Regional Office or OTS Headquarters, you have filed with that office on the next business day. (3) You pay...

  9. 40 CFR 124.10 - Public notice of permit actions and public comment period.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... issued or is required to issue a RCRA, UIC, PSD (or other permit under the Clean Air Act), NPDES, 404... (CONTINUED) WATER PROGRAMS PROCEDURES FOR DECISIONMAKING General Program Requirements § 124.10 Public notice... Act for the same facility or activity (including EPA when the draft permit is prepared by the State...

  10. Evaluation in industry of a draft code of practice for manual handling.

    PubMed

    Ashby, Liz; Tappin, David; Bentley, Tim

    2004-05-01

    This paper reports findings from a study which evaluated the draft New Zealand Code of Practice for Manual Handling. The evaluation assessed the ease of use, applicability and validity of the Code and in particular the associated manual handling hazard assessment tools, within New Zealand industry. The Code was studied in a sample of eight companies from four sectors of industry. Subjective feedback and objective findings indicated that the Code was useful, applicable and informative. The manual handling hazard assessment tools incorporated in the Code could be adequately applied by most users, with risk assessment outcomes largely consistent with the findings of researchers using more specific ergonomics methodologies. However, some changes were recommended to the risk assessment tools to improve usability and validity. The evaluation concluded that both the Code and the tools within it would benefit from simplification, improved typography and layout, and industry-specific information on manual handling hazards.

  11. 75 FR 8299 - Draft Environmental Impact Statement; Determination of Regulated Status of Alfalfa Genetically...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... Engineered for Tolerance to the Herbicide Glyphosate AGENCY: Animal and Plant Health Inspection Service, USDA... to the herbicide glyphosate. State issued photo identification is required and all bags will be...

  12. 75 FR 1585 - Draft Environmental Impact Statement; Determination of Regulated Status of Alfalfa Genetically...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... Engineered for Tolerance to the Herbicide Glyphosate AGENCY: Animal and Plant Health Inspection Service, USDA... to the herbicide glyphosate. State issued photo identification is required and all bags will be...

  13. Superfund Hazard Ranking System Training Course

    EPA Pesticide Factsheets

    The Hazard Ranking System (HRS) training course is a four and ½ day, intermediate-level course designed for personnel who are required to compile, draft, and review preliminary assessments (PAs), site inspections (SIs), and HRS documentation records/packag

  14. Everybody wants it done but nobody wants to do it: an exploration of the barrier and enablers of critical components towards creating a clinical pathway for anxiety and depression in cancer.

    PubMed

    Rankin, Nicole M; Butow, Phyllis N; Thein, Thida; Robinson, Tracy; Shaw, Joanne M; Price, Melanie A; Clover, Kerrie; Shaw, Tim; Grimison, Peter

    2015-01-22

    This study aimed to explore barriers to and enablers for future implementation of a draft clinical pathway for anxiety and depression in cancer patients in the Australian context. Health professionals reviewed a draft clinical pathway and participated in qualitative interviews about the delivery of psychosocial care in their setting, individual components of the draft pathway, and barriers and enablers for its future implementation. Five interrelated themes were identified: ownership; resources and responsibility; education and training; patient reluctance; and integration with health services beyond oncology. The five themes were perceived as both barriers and enablers and provide a basis for an implementation plan that includes strategies to overcome barriers. The next steps are to design and deliver the clinical pathway with specific implementation strategies that address team ownership, endorsement by leaders, education and training modules designed for health professionals and patients and identify ways to integrate the pathway into existing cancer services.

  15. Drafting Fundamentals. Drafting Module 1. Instructor's Guide.

    ERIC Educational Resources Information Center

    Missouri Univ., Columbia. Instructional Materials Lab.

    This Missouri Vocational Instruction Management System instructor's drafting guide has been keyed to the drafting competency profile developed by state industry and education professionals. The guide contains a cross-reference table of instructional materials. Ten units cover drafting fundamentals: (1) introduction to drafting; (2) general safety;…

  16. The genesis of the AIDS policy and AIDS Space in Brazil (1981-1989)

    PubMed Central

    de Barros, Sandra Garrido; Vieira-da-Silva, Ligia Maria

    2016-01-01

    ABSTRACT OBJECTIVE To analyze the genesis of the policy for controlling AIDS in Brazil. METHODS Socio-historical study (1981-1989), based on Bordieu’s genetic sociology, by document analysis, bibliographical review, and in-depth interviews. It consisted of a connection between the analysis of the paths of 33 agents involved in the creation of a social space focusing on AIDS-related issues and the historical possibility conditions of the drafting of a specific policy. RESULTS AIDS Space is a gathering point for the paths of agents from several social fields (medical, scientific, political, and bureaucratic fields). A specific space for relationships, which enabled the drafting of a policy for controlling the AIDS epidemic, but also a place where the authority to talk about the meaning of the disease, the methods to prevent and treat it was under dispute. The analysis showed how the various structures (democratic administrations in Sao Paulo and at the national level, with public health officers taking important positions) and the lack of a specific therapy contributed to social agents of different ranks and backgrounds to initially set prevention as a priority. CONCLUSIONS The rise of the sanitary movement, the organization of SUS, and the dominance of the medical field at the AIDS Space contributed to foster treatment as a part of the measures to control the epidemic. These conditions allowed drafting a policy based on the integrality of care, by linking prevention and treatment in the following decade, with important participation from state bureaucracy and researchers. PMID:27463255

  17. Functional Drafting, Drafting--Intermediate: 9255.02.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    The course consists of six instructional blocks totaling 135 clock hours: (1) functional drafting, (2) threads and fasteners, (3) pictorial drawings, (4) introduction to electronic drafting, (5) introduction to piping drafting, and (6) Quinmester posttest. Mastery of skills indicated in Drafting-Basic--9255.01 is a prerequisite. In the functional…

  18. 76 FR 41808 - Draft Environmental Impact Statement and Draft Habitat Conservation Plan for Oncor Electric...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ...] Draft Environmental Impact Statement and Draft Habitat Conservation Plan for Oncor Electric Delivery..., announce the availability of the draft environmental impact statement and the draft Oncor Electric Delivery... Oncor Electric Delivery Company, LLC (Applicant; Oncor), and (2) That the Applicant has developed a...

  19. Application of self-consolidating concrete in bridge structures : final report.

    DOT National Transportation Integrated Search

    2011-05-01

    The objectives of this research were to evaluate the feasibility and performance of self-consolidating concrete (SCC) made with local aggregates for use in cast-in-place and precast concrete applications and to develop draft specifications, acceptanc...

  20. 76 FR 38740 - Tenth Meeting: RTCA Special Committee 223: Airport Surface Wireless Communications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... Chapters 5,6,8--EUROCAE Chap 5--Service Specific CS Draft Chap 8--Physical Layer Discussion of Security Sub-layer--Honeywell MOPS Outline Wednesday, August 10, 2011 Wednesday Morning--MOPS WG Breakout Session...

  1. 77 FR 34337 - Uinta-Wasatch-Cache National Forest; Evanston-Mountain View Ranger District; Utah; Smiths Fork...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... individuals and organizations who have submitted specific written comments related to the proposed action... the draft EIS will be eligible to file an objection under the Healthy Forests Restoration Act. The...

  2. A Computer Model of Drafting Effects on Collective Behavior in Elite 10,000-m Runners.

    PubMed

    Trenchard, Hugh; Renfree, Andrew; Peters, Derek M

    2017-03-01

    Drafting in cycling influences collective behavior of pelotons. Although evidence for collective behavior in competitive running events exists, it is not clear if this results from energetic savings conferred by drafting. This study modeled the effects of drafting on behavior in elite 10,000-m runners. Using performance data from a men's elite 10,000-m track running event, computer simulations were constructed using Netlogo 5.1 to test the effects of 3 different drafting quantities on collective behavior: no drafting, drafting to 3 m behind with up to ~8% energy savings (a realistic running draft), and drafting up to 3 m behind with up to 38% energy savings (a realistic cycling draft). Three measures of collective behavior were analyzed in each condition: mean speed, mean group stretch (distance between first- and last-placed runner), and runner-convergence ratio (RCR), which represents the degree of drafting benefit obtained by the follower in a pair of coupled runners. Mean speeds were 6.32 ± 0.28, 5.57 ± 0.18, and 5.51 ± 0.13 m/s in the cycling-draft, runner-draft, and no-draft conditions, respectively (all P < .001). RCR was lower in the cycling-draft condition but did not differ between the other 2. Mean stretch did not differ between conditions. Collective behaviors observed in running events cannot be fully explained through energetic savings conferred by realistic drafting benefits. They may therefore result from other, possibly psychological, processes. The benefits or otherwise of engaging in such behavior are as yet unclear.

  3. Superfund Hazard Ranking System Training Course: Table of Contents

    EPA Pesticide Factsheets

    The Hazard Ranking System (HRS) training course is a four and ½ day, intermediate-level course designed for personnel who are required to compile, draft, and review preliminary assessments (PAs), site inspections (SIs), and HRS documentation records/packag

  4. A study of the effect of ADA accessibility on Kansas roundabouts.

    DOT National Transportation Integrated Search

    2008-11-01

    The Access Board, with authority to enforce provisions of the American Disabilities Act (ADA), initially determined : that roundabouts are not accessible by blind pedestrians and drafted proposed guidelines to require pedestrian : signals at all roun...

  5. 77 FR 26521 - Withdrawal of Notice of Intent To Prepare a Joint Draft Supplemental Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... conditions), the regulatory constraints and mitigation requirements for unavoidable impacts to coral reefs..., habitat surveys, and wave response modeling. The public may request copies of reports. The public will be...

  6. 75 FR 42098 - International Conference on Harmonisation; Draft Recommendation for the Revision of the Permitted...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... carcinogenicity study performed by the National Toxicology Program. The new data suggest a positive systemic... alternative approach may be used if such approach satisfies the requirements of the applicable statutes and...

  7. 78 FR 26398 - Public Comment and Public Meeting on Draft Revisions to the Foreign Missions and International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-06

    ... proposals submitted by Federal government agencies for the NCPC review required by law. The Foreign Missions... revised Foreign Missions and International Organizations Element will be available online at http://www...

  8. 76 FR 43355 - Public Comment and Public Meeting on Draft Revisions to the Transportation Element and Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ... government agencies for the NCPC review as required by law. The Transportation Element articulates policies... Transportation and Federal Workplace Elements are available online at http://www.ncpc.gov/compplan . Printed...

  9. 46 CFR 131.220 - Drafts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

  10. 46 CFR 131.220 - Drafts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

  11. 33 CFR 401.29 - Maximum draft.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Maximum draft. 401.29 Section 401... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.29 Maximum draft. (a) The draft...) The draft of a vessel shall not, in any case, exceed 79.2 dm or the maximum permissible draft...

  12. 46 CFR 131.220 - Drafts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

  13. 46 CFR 131.220 - Drafts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

  14. 33 CFR 401.29 - Maximum draft.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Maximum draft. 401.29 Section 401... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.29 Maximum draft. (a) The draft...) The draft of a vessel shall not, in any case, exceed 79.2 dm or the maximum permissible draft...

  15. 46 CFR 131.220 - Drafts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

  16. 76 FR 57760 - Notice of Availability of Draft Resource Management Plan and Draft Environmental Impact Statement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... Availability of Draft Resource Management Plan and Draft Environmental Impact Statement for the Colorado River... prepared a Draft Resource Management Plan (RMP) and Draft Environmental Impact Statement (EIS) for the... alternative) seeks to allocate limited resources among competing human interests, land uses, and conservation...

  17. 33 CFR 401.29 - Maximum draft.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Maximum draft. 401.29 Section 401... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.29 Maximum draft. (a) The draft...) The draft of a vessel shall not, in any case, exceed 79.2 dm or the maximum permissible draft...

  18. 76 FR 59732 - Draft Environmental Impact Statement and Draft Habitat Conservation Plan for Oncor Electric...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ...] Draft Environmental Impact Statement and Draft Habitat Conservation Plan for Oncor Electric Delivery... availability of the draft environmental impact statement (DEIS) and the draft Oncor Electric Delivery Company... announced that Oncor Electric Delivery Company, LLC, has applied under section 10(a)(1)(B) of the Endangered...

  19. LDV survey of cavitation and resonance effect on the precessing vortex rope dynamics in the draft tube of Francis turbines

    NASA Astrophysics Data System (ADS)

    Favrel, A.; Müller, A.; Landry, C.; Yamamoto, K.; Avellan, F.

    2016-11-01

    The large-scale penetration of the electrical grid by intermittent renewable energy sources requires a continuous operating range extension of hydropower plants. This causes the formation of unfavourable flow patterns in the draft tube of turbines and pump-turbines. At partial load operation, a precessing cavitation vortex rope is formed at the Francis turbine runner outlet, acting as an excitation source for the hydraulic system. In case of resonance, the resulting high-amplitude pressure pulsations can put at risk the stability of the machine and of the electrical grid to which it is connected. It is therefore crucial to understand and accurately simulate the underlying physical mechanisms in such conditions. However, the exact impact of cavitation and hydro-acoustic resonance on the flow velocity fluctuations in the draft tube remains to be established. The flow discharge pulsations expected to occur in the draft tube in resonance conditions have for instance never been verified experimentally. In this study, two-component Laser Doppler Velocimetry is used to investigate the axial and tangential velocity fluctuations at the runner outlet of a reduced scale physical model of a Francis turbine. The investigation is performed for a discharge equal to 64 % of the nominal value and three different pressure levels in the draft tube, including resonance and cavitation-free conditions. Based on the convective pressure fluctuations induced by the vortex precession, the periodical velocity fluctuations over one typical precession period are recovered by phase averaging. The impact of cavitation and hydro-acoustic resonance on both axial and tangential velocity fluctuations in terms of amplitude and phase shift is highlighted for the first time. It is shown that the occurrence of resonance does not have significant effects on the draft tube velocity fields, suggesting that the synchronous axial velocity fluctuations are surprisingly negligible compared to the velocity fluctuations induced by the vortex precession.

  20. Guidelines for integrating population education into primary education and literacy programmes.

    PubMed

    1989-01-01

    In recent seminars and workshops in the Asia and Pacific region the integration of population education into primary schools and literacy programs were the main topics. In most of the countries in this area separate courses in population education appear to be unfeasible for primary and secondary schools. In the nonformal area experience has indicated that population education acquires more meaning and relevance if it is integrated into an ongoing development program. The integration approach requires knowledge of the contents of the accommodating subjects or programs and knowledge of the contents of the accommodating subjects or programs and knowledge of the contents of population education. Guidelines suggested include the following steps in developing an integrated curriculum and instructional materials. First determine the needs, characteristics and other background information needed on the target group. Next prioritize the problems and needs of the target group, and formulate educational objectives from the identified needs and problems. Next determine and sequence the curriculum contents and then determine specific population education objectives and contents for integration, and what specific materials have to be developed. Then identify the specific type of format of materials to be developed, and write the first draft of the material. Also prepare illustrations and other art and graphic materials. Then the draft material should be reviewed and translated into the language of the target audience if needed. The materials should then be pretested, or field tested, using a sample of the intended users. To make sure the materials are reaching the target groups and being used effectively, a user's guide should be prepared and teachers and facilitators, as well as supervisors, should be prepared on the use of the material. In addition, a distribution and utilization plan should be prepared. Nonformal education materials can be distributed through libraries, reading center, residences of village leaders, neighborhood stores, and direct mail. The material distribution and utilization should be monitored and evaluated.

  1. Advancing public health obesity policy through state attorneys general.

    PubMed

    Pomeranz, Jennifer L; Brownell, Kelly D

    2011-03-01

    Obesity in the United States exacts a heavy health and financial toll, requiring new approaches to address this public health crisis. State attorneys general have been underutilized in efforts to formulate and implement food and obesity policy solutions. Their authority lies at the intersection of law and public policy, creating unique opportunities unavailable to other officials and government entities. Attorneys general have a broad range of authority over matters specifically relevant to obesity and nutrition policy, including parens patriae (parent of the country) authority, protecting consumer interests, enacting and supporting rules and regulations, working together across states, engaging in consumer education, and drafting opinions and amicus briefs. Significant room exists for greater attorney general involvement in formulating and championing solutions to public health problems such as obesity.

  2. Advancing Public Health Obesity Policy Through State Attorneys General

    PubMed Central

    Brownell, Kelly D.

    2011-01-01

    Obesity in the United States exacts a heavy health and financial toll, requiring new approaches to address this public health crisis. State attorneys general have been underutilized in efforts to formulate and implement food and obesity policy solutions. Their authority lies at the intersection of law and public policy, creating unique opportunities unavailable to other officials and government entities. Attorneys general have a broad range of authority over matters specifically relevant to obesity and nutrition policy, including parens patriae (parent of the country) authority, protecting consumer interests, enacting and supporting rules and regulations, working together across states, engaging in consumer education, and drafting opinions and amicus briefs. Significant room exists for greater attorney general involvement in formulating and championing solutions to public health problems such as obesity. PMID:21233428

  3. Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins.

    PubMed

    Gutiérrez Acosta, Olga B; Schleheck, David; Schink, Bernhard

    2014-07-11

    The sulfate-reducing bacterium Desulfococcus biacutus is able to utilize acetone for growth by an inducible degradation pathway that involves a novel activation reaction for acetone with CO as a co-substrate. The mechanism, enzyme(s) and gene(s) involved in this acetone activation reaction are of great interest because they represent a novel and yet undefined type of activation reaction under strictly anoxic conditions. In this study, a draft genome sequence of D. biacutus was established. Sequencing, assembly and annotation resulted in 159 contigs with 5,242,029 base pairs and 4773 predicted genes; 4708 were predicted protein-encoding genes, and 3520 of these had a functional prediction. Proteins and genes were identified that are specifically induced during growth with acetone. A thiamine diphosphate-requiring enzyme appeared to be highly induced during growth with acetone and is probably involved in the activation reaction. Moreover, a coenzyme B12- dependent enzyme and proteins that are involved in redox reactions were also induced during growth with acetone. We present for the first time the genome of a sulfate reducer that is able to grow with acetone. The genome information of this organism represents an important tool for the elucidation of a novel reaction mechanism that is employed by a sulfate reducer in acetone activation.

  4. A comprehensive draft genome sequence for lupin (Lupinus angustifolius), an emerging health food: insights into plant-microbe interactions and legume evolution.

    PubMed

    Hane, James K; Ming, Yao; Kamphuis, Lars G; Nelson, Matthew N; Garg, Gagan; Atkins, Craig A; Bayer, Philipp E; Bravo, Armando; Bringans, Scott; Cannon, Steven; Edwards, David; Foley, Rhonda; Gao, Ling-Ling; Harrison, Maria J; Huang, Wei; Hurgobin, Bhavna; Li, Sean; Liu, Cheng-Wu; McGrath, Annette; Morahan, Grant; Murray, Jeremy; Weller, James; Jian, Jianbo; Singh, Karam B

    2017-03-01

    Lupins are important grain legume crops that form a critical part of sustainable farming systems, reducing fertilizer use and providing disease breaks. It has a basal phylogenetic position relative to other crop and model legumes and a high speciation rate. Narrow-leafed lupin (NLL; Lupinus angustifolius L.) is gaining popularity as a health food, which is high in protein and dietary fibre but low in starch and gluten-free. We report the draft genome assembly (609 Mb) of NLL cultivar Tanjil, which has captured >98% of the gene content, sequences of additional lines and a dense genetic map. Lupins are unique among legumes and differ from most other land plants in that they do not form mycorrhizal associations. Remarkably, we find that NLL has lost all mycorrhiza-specific genes, but has retained genes commonly required for mycorrhization and nodulation. In addition, the genome also provided candidate genes for key disease resistance and domestication traits. We also find evidence of a whole-genome triplication at around 25 million years ago in the genistoid lineage leading to Lupinus. Our results will support detailed studies of legume evolution and accelerate lupin breeding programmes. © 2016 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

  5. Clinical evaluation of the FreeStyle Precision Pro system.

    PubMed

    Brazg, Ronald; Hughes, Kristen; Martin, Pamela; Coard, Julie; Toffaletti, John; McDonnell, Elizabeth; Taylor, Elizabeth; Farrell, Lausanne; Patel, Mona; Ward, Jeanne; Chen, Ting; Alva, Shridhara; Ng, Ronald

    2013-06-05

    A new version of international standard (ISO 15197) and CLSI Guideline (POCT12) with more stringent accuracy criteria are near publication. We evaluated the glucose test performance of the FreeStyle Precision Pro system, a new blood glucose monitoring system (BGMS) designed to enhance accuracy for point-of-care testing (POCT). Precision, interference and system accuracy with 503 blood samples from capillary, venous and arterial sources were evaluated in a multicenter study. Study results were analyzed and presented in accordance with the specifications and recommendations of the final draft ISO 15197 and the new POCT12. The FreeStyle Precision Pro system demonstrated acceptable precision (CV <5%), no interference across a hematocrit range of 15-65%, and, except for xylose, no interference from 24 of 25 potentially interfering substances. It also met all accuracy criteria specified in the final draft ISO 15197 and POCT12, with 97.3-98.9% of the individual results of various blood sample types agreeing within ±12 mg/dl of the laboratory analyzer values at glucose concentrations <100mg/dl and within ±12.5% of the laboratory analyzer values at glucose concentrations ≥100 mg/dl. The FreeStyle Precision Pro system met the tighter accuracy requirements, providing a means for enhancing accuracy for point-of-care blood glucose monitoring. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. Validation of Minimum Display Requirements for a UAS Detect and Avoid System

    NASA Technical Reports Server (NTRS)

    Rorie, Conrad; Fern, Lisa; Roberts, Zach; Monk, Kevin; Santiago, Confesor; Shively, Jay

    2017-01-01

    The full integration of Unmanned Aircraft Systems (UAS) into the National Airspace System (NAS), a prerequisite for enabling a broad range of public and commercial UAS operations, presents several technical challenges to UAS developers, operators and regulators. A primary barrier is the inability for UAS pilots (situated at a ground control station, or GCS) to comply with Title 14 Code of Federal Regulations sections 91.111 and 91.113, which require pilots to see and avoid other aircraft in order to maintain well clear. The present study is the final in a series of human-in-the-loop experiments designed to explore and test the various display and alerting requirements being incorporated into the minimum operational performance standards (MOPS) for a UAS-specific detect and avoid system that would replace the see and avoid function required of manned aircraft. Two display configurations were tested - an integrated display and a standalone display - and their impact on pilot response times and ability to maintain DAA well clear were compared. Results indicated that the current draft of the MOPS result in high-level performance and did not meaningfully differ by display configuration.

  7. Motivations, aims and communication around advance directives: a mixed-methods study into the perspective of their owners and the influence of a current illness.

    PubMed

    van Wijmen, Matthijs P S; Pasman, H Roeline W; Widdershoven, Guy A M; Onwuteaka-Philipsen, Bregje D

    2014-06-01

    What are motivations of owners of an advance directive (AD) to draft an AD, what do they aim for with their AD and do they communicate about their AD? Written questionnaires were sent to a cohort of people owning different types of ADs (n=5768). A purposive sample of people suffering from an illness was selected from the cohort for an in-depth interview (n=29). About half of our population had no direct motivation to draft their AD. Most mentioned motivation for the other half was an illness of a family member or friend. Many different and specific aims for drafting an AD were mentioned. An often mentioned more general aim in people with different ADs was to prevent unnecessary lengthening of life or treatment (14-16%). Most respondents communicated about having an AD with close-ones (63-88%) and with their GP (65-79%). In the interviews people gave vivid examples of experiences of what they hoped to prevent at the end of life. Some mentioned difficulties foreseeing the future and gave examples of response shift. ADs can give directions to caregivers about what people want at the end of life. ADs have to be discussed in detail by their owners and caregivers, since owners often have specific aims with their AD. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  8. Determination of dissolved bromate in drinking water by ion chromatography and post column reaction: interlaboratory study.

    PubMed

    Cordeiro, Fernando; Robouch, Piotr; de la Calle, Maria Beatriz; Emteborg, Håkan; Charoud-Got, Jean; Schmitz, Franz

    2011-01-01

    A collaborative study, International Evaluation Measurement Programme-25a, was conducted in accordance with international protocols to determine the performance characteristics of an analytical method for the determination of dissolved bromate in drinking water. The method should fulfill the analytical requirements of Council Directive 98/83/EC (referred to in this work as the Drinking Water Directive; DWD). The new draft standard method under investigation is based on ion chromatography followed by post-column reaction and UV detection. The collaborating laboratories used the Draft International Organization for Standardization (ISO)/Draft International Standard (DIS) 11206 document. The existing standard method (ISO 15061:2001) is based on ion chromatography using suppressed conductivity detection, in which a preconcentration step may be required for the determination of bromate concentrations as low as 3 to 5 microg/L. The new method includes a dilution step that reduces the matrix effects, thus allowing the determination of bromate concentrations down to 0.5 microg/L. Furthermore, the method aims to minimize any potential interference of chlorite ions. The collaborative study investigated different types of drinking water, such as soft, hard, and mineral water. Other types of water, such as raw water (untreated), swimming pool water, a blank (named river water), and a bromate standard solution, were included as test samples. All test matrixes except the swimming pool water were spiked with high-purity potassium bromate to obtain bromate concentrations ranging from 1.67 to 10.0 microg/L. Swimming pool water was not spiked, as this water was incurred with bromate. Test samples were dispatched to 17 laboratories from nine different countries. Sixteen participants reported results. The repeatability RSD (RSD(r)) ranged from 1.2 to 4.1%, while the reproducibility RSD (RSDR) ranged from 2.3 to 5.9%. These precision characteristics compare favorably with those of ISO 15601. A thorough comparison of the performance characteristics is presented in this report. All method performance characteristics obtained in the frame of this collaborative study indicate that the draft ISO/DIS 11206 standard method meets the requirements set down by the DWD. It can, therefore, be considered to fit its intended analytical purpose.

  9. The draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan.

    PubMed

    Wang, Zhuo; Pascual-Anaya, Juan; Zadissa, Amonida; Li, Wenqi; Niimura, Yoshihito; Huang, Zhiyong; Li, Chunyi; White, Simon; Xiong, Zhiqiang; Fang, Dongming; Wang, Bo; Ming, Yao; Chen, Yan; Zheng, Yuan; Kuraku, Shigehiro; Pignatelli, Miguel; Herrero, Javier; Beal, Kathryn; Nozawa, Masafumi; Li, Qiye; Wang, Juan; Zhang, Hongyan; Yu, Lili; Shigenobu, Shuji; Wang, Junyi; Liu, Jiannan; Flicek, Paul; Searle, Steve; Wang, Jun; Kuratani, Shigeru; Yin, Ye; Aken, Bronwen; Zhang, Guojie; Irie, Naoki

    2013-06-01

    The unique anatomical features of turtles have raised unanswered questions about the origin of their unique body plan. We generated and analyzed draft genomes of the soft-shell turtle (Pelodiscus sinensis) and the green sea turtle (Chelonia mydas); our results indicated the close relationship of the turtles to the bird-crocodilian lineage, from which they split ∼267.9-248.3 million years ago (Upper Permian to Triassic). We also found extensive expansion of olfactory receptor genes in these turtles. Embryonic gene expression analysis identified an hourglass-like divergence of turtle and chicken embryogenesis, with maximal conservation around the vertebrate phylotypic period, rather than at later stages that show the amniote-common pattern. Wnt5a expression was found in the growth zone of the dorsal shell, supporting the possible co-option of limb-associated Wnt signaling in the acquisition of this turtle-specific novelty. Our results suggest that turtle evolution was accompanied by an unexpectedly conservative vertebrate phylotypic period, followed by turtle-specific repatterning of development to yield the novel structure of the shell.

  10. Automatic draft reading based on image processing

    NASA Astrophysics Data System (ADS)

    Tsujii, Takahiro; Yoshida, Hiromi; Iiguni, Youji

    2016-10-01

    In marine transportation, a draft survey is a means to determine the quantity of bulk cargo. Automatic draft reading based on computer image processing has been proposed. However, the conventional draft mark segmentation may fail when the video sequence has many other regions than draft marks and a hull, and the estimated waterline is inherently higher than the true one. To solve these problems, we propose an automatic draft reading method that uses morphological operations to detect draft marks and estimate the waterline for every frame with Canny edge detection and a robust estimation. Moreover, we emulate surveyors' draft reading process for getting the understanding of a shipper and a receiver. In an experiment in a towing tank, the draft reading error of the proposed method was <1 cm, showing the advantage of the proposed method. It is also shown that accurate draft reading has been achieved in a real-world scene.

  11. A TIERED APPROACH TO PERFORMING UNCERTAINTY ANALYSIS IN CONDUCTING EXPOSURE ANALYSIS FOR CHEMICALS

    EPA Science Inventory

    The WHO/IPCS draft Guidance Document on Characterizing and Communicating Uncertainty in Exposure Assessment provides guidance on recommended strategies for conducting uncertainty analysis as part of human exposure analysis. Specifically, a tiered approach to uncertainty analysis ...

  12. A-BOMB SURVIVOR SITE-SPECIFIC RADIOGENIC CANCER RISKS ESTIMATES

    EPA Science Inventory

    A draft manuscript is being prepared that describes ways to improve estimates of risk from radiation that have been derived from A-bomb survivors. The work has been published in the journal Radiation Research volume 169, pages 87-98.

  13. Metadata for WIS and WIGOS: GAW Profile of ISO19115 and Draft WIGOS Core Metadata Standard

    NASA Astrophysics Data System (ADS)

    Klausen, Jörg; Howe, Brian

    2014-05-01

    The World Meteorological Organization (WMO) Integrated Global Observing System (WIGOS) is a key WMO priority to underpin all WMO Programs and new initiatives such as the Global Framework for Climate Services (GFCS). The development of the WIGOS Operational Information Resource (WIR) is central to the WIGOS Framework Implementation Plan (WIGOS-IP). The WIR shall provide information on WIGOS and its observing components, as well as requirements of WMO application areas. An important aspect is the description of the observational capabilities by way of structured metadata. The Global Atmosphere Watch is the WMO program addressing the chemical composition and selected physical properties of the atmosphere. Observational data are collected and archived by GAW World Data Centres (WDCs) and related data centres. The Task Team on GAW WDCs (ET-WDC) have developed a profile of the ISO19115 metadata standard that is compliant with the WMO Information System (WIS) specification for the WMO Core Metadata Profile v1.3. This profile is intended to harmonize certain aspects of the documentation of observations as well as the interoperability of the WDCs. The Inter-Commission-Group on WIGOS (ICG-WIGOS) has established the Task Team on WIGOS Metadata (TT-WMD) with representation of all WMO Technical Commissions and the objective to define the WIGOS Core Metadata. The result of this effort is a draft semantic standard comprising of a set of metadata classes that are considered to be of critical importance for the interpretation of observations relevant to WIGOS. The purpose of the presentation is to acquaint the audience with the standard and to solicit informal feed-back from experts in the various disciplines of meteorology and climatology. This feed-back will help ET-WDC and TT-WMD to refine the GAW metadata profile and the draft WIGOS metadata standard, thereby increasing their utility and acceptance.

  14. Drafting: Current Trends and Future Practices

    ERIC Educational Resources Information Center

    Jensen, C.

    1976-01-01

    Various research findings are reported on drafting trends which the author feels should be incorporated into teaching drafting: (1) true position and geometric tolerancing, (2) decimal and metric dimensioning, (3) functional drafting, (4) automated drafting, and (5) drawing reproductions. (BP)

  15. Mississippi Curriculum Framework for Drafting and Design Technology (Program CIP: 48.0102--Architectural Drafting Technology) (Program CIP: 48.0101--General Drafting). Postsecondary Programs.

    ERIC Educational Resources Information Center

    Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.

    This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the two course sequences of the state's postsecondary-level drafting and design technology program: architectural drafting technology and drafting and design technology. Presented first are a program description and…

  16. 75 FR 81284 - Nationwide Use of High Frequency and Ultra High Frequency Active SONAR Technology; Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ... such as: The attacks of September 11, 2001; natural disasters such as Hurricanes Katrina and Rita of... technology during times of extreme weather, such as hurricanes, could be required for onshore areas that...

  17. Induced traffic and induced demand in benefit-cost analysis - draft

    DOT National Transportation Integrated Search

    1998-07-01

    Subsequent to the US DOT's 1995 "conditions and Performance" report to Congress, the HERS (Highway Economic Requirements System) model used by FHWA to evaluate national highway investment options was modified to incorporate both short run and long ru...

  18. Materials for the WIIN Strategic Plan

    EPA Pesticide Factsheets

    EPA will also be hosting a webinar on March 23, 2017 to review a draft strategic plan that identifies roles and responsibilities for EPA, states and PWS under the requirements of WIIN. EPA will also be hosting a follow up webinar in May.

  19. Helping Students Avoid Plagiarism.

    ERIC Educational Resources Information Center

    Wilhoit, Stephen

    1994-01-01

    Discusses how and why college students commit plagiarism, suggesting techniques that instructors can use to help student avoid plagiarism. Instructors should define and discuss plagiarism thoroughly; discuss hypothetical cases; review the conventions of quoting and documenting material; require multiple drafts of essays; and offer responses…

  20. 78 FR 3453 - Public Comment and Public Meeting on Draft Revisions to the Visitors Element of the Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... NCPC review required by law. The Federal Visitors and Commemorative Works Element articulates policies... Element will be available online at http://www.ncpc.gov/compplan by Monday, January 14, 2013. Printed...

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