Establishing the fundamentals for an elephant early warning and monitoring system.

PubMed

Zeppelzauer, Matthias; Stoeger, Angela S

2015-09-04

The decline of habitat for elephants due to expanding human activity is a serious conservation problem. This has continuously escalated the human-elephant conflict in Africa and Asia. Elephants make extensive use of powerful infrasonic calls (rumbles) that travel distances of up to several kilometers. This makes elephants well-suited for acoustic monitoring because it enables detecting elephants even if they are out of sight. In sight, their distinct visual appearance makes them a good candidate for visual monitoring. We provide an integrated overview of our interdisciplinary project that established the scientific fundamentals for a future early warning and monitoring system for humans who regularly experience serious conflict with elephants. We first draw the big picture of an early warning and monitoring system, then review the developed solutions for automatic acoustic and visual detection, discuss specific challenges and present open future work necessary to build a robust and reliable early warning and monitoring system that is able to operate in situ. We present a method for the automated detection of elephant rumbles that is robust to the diverse noise sources present in situ. We evaluated the method on an extensive set of audio data recorded under natural field conditions. Results show that the proposed method outperforms existing approaches and accurately detects elephant rumbles. Our visual detection method shows that tracking elephants in wildlife videos (of different sizes and postures) is feasible and particularly robust at near distances. From our project results we draw a number of conclusions that are discussed and summarized. We clearly identified the most critical challenges and necessary improvements of the proposed detection methods and conclude that our findings have the potential to form the basis for a future automated early warning system for elephants. We discuss challenges that need to be solved and summarize open topics in the context of a future early warning and monitoring system. We conclude that a long-term evaluation of the presented methods in situ using real-time prototypes is the most important next step to transfer the developed methods into practical implementation.

The drawing effect: Evidence for reliable and robust memory benefits in free recall.

PubMed

Wammes, Jeffrey D; Meade, Melissa E; Fernandes, Myra A

2016-01-01

In 7 free-recall experiments, the benefit of creating drawings of to-be-remembered information relative to writing was examined as a mnemonic strategy. In Experiments 1 and 2, participants were presented with a list of words and were asked to either draw or write out each. Drawn words were better recalled than written. Experiments 3-5 showed that the memory boost provided by drawing could not be explained by elaborative encoding (deep level of processing, LoP), visual imagery, or picture superiority, respectively. In Experiment 6, we explored potential limitations of the drawing effect, by reducing encoding time and increasing list length. Drawing, relative to writing, still benefited memory despite these constraints. In Experiment 7, the drawing effect was significant even when encoding trial types were compared in pure lists between participants, inconsistent with a distinctiveness account. Together these experiments indicate that drawing enhances memory relative to writing, across settings, instructions, and alternate encoding strategies, both within- and between-participants, and that a deep LoP, visual imagery, or picture superiority, alone or collectively, are not sufficient to explain the observed effect. We propose that drawing improves memory by encouraging a seamless integration of semantic, visual, and motor aspects of a memory trace.

A Bayesian Approach to the Paleomagnetic Conglomerate Test

NASA Astrophysics Data System (ADS)

Heslop, David; Roberts, Andrew P.

2018-02-01

The conglomerate test has served the paleomagnetic community for over 60 years as a means to detect remagnetizations. The test states that if a suite of clasts within a bed have uniformly random paleomagnetic directions, then the conglomerate cannot have experienced a pervasive event that remagnetized the clasts in the same direction. The current form of the conglomerate test is based on null hypothesis testing, which results in a binary "pass" (uniformly random directions) or "fail" (nonrandom directions) outcome. We have recast the conglomerate test in a Bayesian framework with the aim of providing more information concerning the level of support a given data set provides for a hypothesis of uniformly random paleomagnetic directions. Using this approach, we place the conglomerate test in a fully probabilistic framework that allows for inconclusive results when insufficient information is available to draw firm conclusions concerning the randomness or nonrandomness of directions. With our method, sample sets larger than those typically employed in paleomagnetism may be required to achieve strong support for a hypothesis of random directions. Given the potentially detrimental effect of unrecognized remagnetizations on paleomagnetic reconstructions, it is important to provide a means to draw statistically robust data-driven inferences. Our Bayesian analysis provides a means to do this for the conglomerate test.

The IARC monographs: critics and controversy.

PubMed

Samet, Jonathan M

2015-07-01

The monograph program of the International Agency for Research on Cancer (IARC), which relies on the efforts of volunteer Working Groups, uses a transparent approach to evaluate the carcinogenicity of agents for which scoping has determined that there is sufficient evidence to warrant a review. Because of the potentially powerful implications of the conclusions of the monographs and the sometimes challenging nature of the evidence reviewed, the monographs and the IARC process have been criticized from time to time. This commentary describes the IARC monograph process and addresses recent criticisms of the program, drawing on a recent defense of the program authored by 124 researchers. These authors concluded that the IARC processes are robust and transparent and not flawed and biased as suggested by some critics. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dr. George L. Mesina; Steven P. Miller

The XMGR5 graphing package [1] for drawing RELAP5 [2] plots is being re-written in Java [3]. Java is a robust programming language that is available at no cost for most computer platforms from Sun Microsystems, Inc. XMGR5 is an extension of an XY plotting tool called ACE/gr extended to plot data from several US Nuclear Regulatory Commission (NRC) applications. It is also the most popular graphing package worldwide for making RELAP5 plots. In Section 1, a short review of XMGR5 is given, followed by a brief overview of Java. In Section 2, shortcomings of both tkXMGR [4] and XMGR5 aremore » discussed and the value of converting to Java is given. Details of the conversion to Java are given in Section 3. The progress to date, some conclusions and future work are given in Section 4. Some screen shots of the Java version are shown.« less

Implementation of a graphical user interface for the virtual multifrequency spectrometer: The VMS-Draw tool.

PubMed

Licari, Daniele; Baiardi, Alberto; Biczysko, Malgorzata; Egidi, Franco; Latouche, Camille; Barone, Vincenzo

2015-02-15

This article presents the setup and implementation of a graphical user interface (VMS-Draw) for a virtual multifrequency spectrometer. Special attention is paid to ease of use, generality and robustness for a panel of spectroscopic techniques and quantum mechanical approaches. Depending on the kind of data to be analyzed, VMS-Draw produces different types of graphical representations, including two-dimensional or three-dimesional (3D) plots, bar charts, or heat maps. Among other integrated features, one may quote the convolution of stick spectra to obtain realistic line-shapes. It is also possible to analyze and visualize, together with the structure, the molecular orbitals and/or the vibrational motions of molecular systems thanks to 3D interactive tools. On these grounds, VMS-Draw could represent a useful additional tool for spectroscopic studies integrating measurements and computer simulations. Copyright © 2014 Wiley Periodicals, Inc.

Fructose, high-fructose corn syrup, sucrose, and nonalcoholic fatty liver disease or indexes of liver health: a systematic review and meta-analysis1234

PubMed Central

Chung, Mei; Ma, Jiantao; Patel, Kamal; Berger, Samantha; Lau, Joseph; Lichtenstein, Alice H

2014-01-01

Background: Concerns have been raised about the concurrent temporal trend between simple sugar intakes, especially of fructose or high-fructose corn syrup (HFCS), and rates of nonalcoholic fatty liver disease (NAFLD) in the United States. Objective: We examined the effect of different amounts and forms of dietary fructose on the incidence or prevalence of NAFLD and indexes of liver health in humans. Design: We conducted a systematic review of English-language, human studies of any design in children and adults with low to no alcohol intake and that reported at least one predetermined measure of liver health. The strength of the evidence was evaluated by considering risk of bias, consistency, directness, and precision. Results: Six observational studies and 21 intervention studies met the inclusion criteria. The overall strength of evidence for observational studies was rated insufficient because of high risk of biases and inconsistent study findings. Of 21 intervention studies, 19 studies were in adults without NAFLD (predominantly healthy, young men) and 1 study each in adults or children with NAFLD. We found a low level of evidence that a hypercaloric fructose diet (supplemented by pure fructose) increases liver fat and aspartate aminotransferase (AST) concentrations in healthy men compared with the consumption of a weight-maintenance diet. In addition, there was a low level of evidence that hypercaloric fructose and glucose diets have similar effects on liver fat and liver enzymes in healthy adults. There was insufficient evidence to draw a conclusion for effects of HFCS or sucrose on NAFLD. Conclusions: On the basis of indirect comparisons across study findings, the apparent association between indexes of liver health (ie, liver fat, hepatic de novo lipogenesis, alanine aminotransferase, AST, and γ-glutamyl transpeptase) and fructose or sucrose intake appear to be confounded by excessive energy intake. Overall, the available evidence is not sufficiently robust to draw conclusions regarding effects of fructose, HFCS, or sucrose consumption on NAFLD. PMID:25099546

Two-stage neural-network-based technique for Urdu character two-dimensional shape representation, classification, and recognition

NASA Astrophysics Data System (ADS)

Megherbi, Dalila B.; Lodhi, S. M.; Boulenouar, A. J.

2001-03-01

This work is in the field of automated document processing. This work addresses the problem of representation and recognition of Urdu characters using Fourier representation and a Neural Network architecture. In particular, we show that a two-stage Neural Network scheme is used here to make classification of 36 Urdu characters into seven sub-classes namely subclasses characterized by seven proposed and defined fuzzy features specifically related to Urdu characters. We show that here Fourier Descriptors and Neural Network provide a remarkably simple way to draw definite conclusions from vague, ambiguous, noisy or imprecise information. In particular, we illustrate the concept of interest regions and describe a framing method that provides a way to make the proposed technique for Urdu characters recognition robust and invariant to scaling and translation. We also show that a given character rotation is dealt with by using the Hotelling transform. This transform is based upon the eigenvalue decomposition of the covariance matrix of an image, providing a method of determining the orientation of the major axis of an object within an image. Finally experimental results are presented to show the power and robustness of the proposed two-stage Neural Network based technique for Urdu character recognition, its fault tolerance, and high recognition accuracy.

Perceptual Drawing as a Learning Tool in a College Biology Laboratory

NASA Astrophysics Data System (ADS)

Landin, Jennifer

2011-12-01

The use of drawing in the classroom has a contentious history in the U.S. education system. While most instructors and students agree that the activity helps students focus and observe more details, there is a lack of empirical data to support these positions. This study examines the use of three treatments (writing a description, drawing a perceptual image, or drawing a perceptual image after participating in a short instructional lesson on perceptual drawing) each week over the course of a semester. The students in the "Drawing with Instruction" group exhibit a small but significantly higher level of content knowledge by the end of the semester. When comparing Attitude Toward Biology and Observational Skills among the three groups, inconclusive results restrict making any conclusions. Student perceptions of the task are positive, although not as strong as indicated by other studies. A student behavior observed during the first study led to another question regarding student cognitive processes, and demonstrated cognitive change in student-rendered drawings. The data from the second study indicate that hemispheric dominance or visual/verbal learning do not impact learning from perceptual drawing activities. However, conservatism and need for closure are inversely proportional to the change seen in student drawings over the course of a lesson. Further research is needed to verify these conclusions, as the second study has a small number of participants.

Tuning Monotonic Basin Hopping: Improving the Efficiency of Stochastic Search as Applied to Low-Thrust Trajectory Optimization

NASA Technical Reports Server (NTRS)

Englander, Jacob; Englander, Arnold

2014-01-01

Trajectory optimization methods using MBH have become well developed during the past decade. An essential component of MBH is a controlled random search through the multi-dimensional space of possible solutions. Historically, the randomness has been generated by drawing RVs from a uniform probability distribution. Here, we investigate the generating the randomness by drawing the RVs from Cauchy and Pareto distributions, chosen because of their characteristic long tails. We demonstrate that using Cauchy distributions (as first suggested by Englander significantly improves MBH performance, and that Pareto distributions provide even greater improvements. Improved performance is defined in terms of efficiency and robustness, where efficiency is finding better solutions in less time, and robustness is efficiency that is undiminished by (a) the boundary conditions and internal constraints of the optimization problem being solved, and (b) by variations in the parameters of the probability distribution. Robustness is important for achieving performance improvements that are not problem specific. In this work we show that the performance improvements are the result of how these long-tailed distributions enable MBH to search the solution space faster and more thoroughly. In developing this explanation, we use the concepts of sub-diffusive, normally-diffusive, and super-diffusive RWs originally developed in the field of statistical physics.

Learning terms and definitions: Drawing and the role of elaborative encoding.

PubMed

Wammes, Jeffrey D; Meade, Melissa E; Fernandes, Myra A

2017-09-01

Traditionally, students adopt the strategy of taking written notes when attending a class or learning from a textbook in educational settings. Informed by previous work showing that learning by doing improves memory performance, we examined whether drawing to-be-remembered definitions from university textbooks would improve later memory, relative to a more typical strategy of rote transcription. Participants were asked to either write out the definition, or to draw a picture representative of the definition. Results indicated that drawing, relative to verbatim writing, conferred a reliable memorial benefit that was robust, even when participants' preexisting familiarity with the terms was included as a covariate (in Experiment 1) or when the to-be-remembered terms and definitions were fictitious, thus removing the influence of familiarity (in Experiment 2). We reasoned that drawing likely facilitates retention at least in part because at encoding, participants must retain and elaborate upon information regarding the meaning of the definition, to translate it into a new form (a picture). This is not the case when participants write out the definitions verbatim. In Experiment 3 we showed that paraphrasing during encoding, which, like drawing and in contrast with verbatim writing, requires self-generated elaboration, led to memory performance that was comparable to drawing. Taken together, results suggest that drawing is a powerful tool which improves memory, and that drawing produces a similar level of retention as does paraphrasing. This suggests that elaborative encoding plays a critical role in the memorial benefit that drawing confers to memory for definitions of academic terms. Copyright © 2017 Elsevier B.V. All rights reserved.

Drawing conclusions: The effect of instructions on children's confabulation and fantasy errors.

PubMed

Macleod, Emily; Gross, Julien; Hayne, Harlene

2016-01-01

Drawing is commonly used in forensic and clinical interviews with children. In these interviews, children are often allowed to draw without specific instructions about the purpose of the drawing materials. Here, we examined whether this practice influenced the accuracy of children's reports. Seventy-four 5- and 6-year-old children were interviewed one to two days after they took part in an interactive event. Some children were given drawing materials to use during the interview. Of these children, some were instructed to draw about the event, and some were given no additional instructions at all. Children who were instructed to draw about the event, or who were interviewed without drawing, made few errors. In contrast, children who drew without being given specific instructions reported more errors that were associated with both confabulation and fantasy. We conclude that, to maximise accuracy during interviews involving drawing, children should be directed to draw specifically about the interview topic.

Covert checks by standardised patients of general practitioners' delivery of new periodic health examinations: clustered cross-sectional study from a consumer organisation

PubMed Central

Thaler, Kylie; Harris, Mark F

2012-01-01

Objective To assess if data collected by a consumer organisation are valid for a health service research study on physicians' performance in preventive care. To report first results of the analysis of physicians performance like consultation time and guideline adherence in history taking. Design Secondary data analysis of a clustered cross-sectional direct observation survey. Setting General practitioners (GPs) in Vienna, Austria, visited unannounced by mystery shoppers (incognito standardised patients (ISPs)). Participants 21 randomly selected GPs were visited by two different ISPs each. 40 observation protocols were realised. Main outcome measures Robustness of sampling and data collection by the consumer organisation. GPs consultation and waiting times, guideline adherence in history taking. Results The double stratified random sampling method was robust and representative for the private and contracted GPs mix of Vienna. The clinical scenarios presented by the ISPs were valid and believable, and no GP realised the ISPs were not genuine patients. The average consultation time was 46 min (95% CI 37 to 54 min). Waiting times differed more than consultation times between private and contracted GPs. No differences between private and contracted GPs in terms of adherence to the evidence-based guidelines regarding history taking including questions regarding alcohol use were found. According to the analysis, 20% of the GPs took a perfect history (95% CI 9% to 39%). Conclusions The analysis of secondary data collected by a consumer organisation was a valid method for drawing conclusions about GPs preventive practice. Initial results, like consultation times longer than anticipated, and the moderate quality of history taking encourage continuing the analysis on available clinical data. PMID:22872721

Ethno-Experiments: Creating Robust Inquiry and Futures

ERIC Educational Resources Information Center

Ramsey, Caroline

2007-01-01

This article introduces a practice-centred inquiry method called an "ethno-experiment". The method is built on a social constructionist understanding of practice as a social performance rather than as an individual's act. Additionally, it draws on Garfinkel's early ethnomethodological work and Marshall's self-reflective inquiry to construct a…

Review of Recent Literature on Figure Drawing Tests as Related to Research Problems in Art Education

ERIC Educational Resources Information Center

McWhinnie, Harold J.

1971-01-01

McFee's perception-delineation theory is supported. Major methodological problems of the psychological research presented are in the area of set and the control of specific art materials. Among the conclusions: figure drawing may not be culture fair; a person trained in visual arts should be employed in research using figure drawing tests. (VW)

Doubly robust nonparametric inference on the average treatment effect.

PubMed

Benkeser, D; Carone, M; Laan, M J Van Der; Gilbert, P B

2017-12-01

Doubly robust estimators are widely used to draw inference about the average effect of a treatment. Such estimators are consistent for the effect of interest if either one of two nuisance parameters is consistently estimated. However, if flexible, data-adaptive estimators of these nuisance parameters are used, double robustness does not readily extend to inference. We present a general theoretical study of the behaviour of doubly robust estimators of an average treatment effect when one of the nuisance parameters is inconsistently estimated. We contrast different methods for constructing such estimators and investigate the extent to which they may be modified to also allow doubly robust inference. We find that while targeted minimum loss-based estimation can be used to solve this problem very naturally, common alternative frameworks appear to be inappropriate for this purpose. We provide a theoretical study and a numerical evaluation of the alternatives considered. Our simulations highlight the need for and usefulness of these approaches in practice, while our theoretical developments have broad implications for the construction of estimators that permit doubly robust inference in other problems.

Tuning Monotonic Basin Hopping: Improving the Efficiency of Stochastic Search as Applied to Low-Thrust Trajectory Optimization

NASA Technical Reports Server (NTRS)

Englander, Jacob A.; Englander, Arnold C.

2014-01-01

Trajectory optimization methods using monotonic basin hopping (MBH) have become well developed during the past decade [1, 2, 3, 4, 5, 6]. An essential component of MBH is a controlled random search through the multi-dimensional space of possible solutions. Historically, the randomness has been generated by drawing random variable (RV)s from a uniform probability distribution. Here, we investigate the generating the randomness by drawing the RVs from Cauchy and Pareto distributions, chosen because of their characteristic long tails. We demonstrate that using Cauchy distributions (as first suggested by J. Englander [3, 6]) significantly improves monotonic basin hopping (MBH) performance, and that Pareto distributions provide even greater improvements. Improved performance is defined in terms of efficiency and robustness. Efficiency is finding better solutions in less time. Robustness is efficiency that is undiminished by (a) the boundary conditions and internal constraints of the optimization problem being solved, and (b) by variations in the parameters of the probability distribution. Robustness is important for achieving performance improvements that are not problem specific. In this work we show that the performance improvements are the result of how these long-tailed distributions enable MBH to search the solution space faster and more thoroughly. In developing this explanation, we use the concepts of sub-diffusive, normally-diffusive, and super-diffusive random walks (RWs) originally developed in the field of statistical physics.

Reporting from Qatar, this is Al-Jazeera

DTIC Science & Technology

2006-03-15

facts of the stories and draw conclusions to Al-Jazeera’s motives and the effects of its reporting on U.S. military operations in Iraq. REPORTING FROM...vignettes examine the facts of the stories and draw conclusions to Al-Jazeera’s motives and the effects of its reporting on U.S. military operations...after a period of five years and no longer reliant on state funds through the sale of program advertisement and exclusive video footage to other

Business recovery: an assessment framework.

PubMed

Stevenson, Joanne R; Brown, Charlotte; Seville, Erica; Vargo, John

2018-07-01

This paper presents a Business Recovery Assessment Framework (BRAF) to help researchers and practitioners design robust, repeatable, and comparable studies of business recovery in various post-disruption contexts. Studies assessing business recovery without adequately considering the research aims, recovery definitions, and indicators can produce misleading findings. The BRAF is composed of a series of steps that guide the decisions that researchers need to make to ensure: (i) that recovery is indeed being measured; (ii) that the indicators of recovery that are selected align with the objectives of the study and the definition of recovery; and, where necessary, (iii) that appropriate comparative control variables are in place. The paper draws on a large dataset of business surveys collected following the earthquakes in Canterbury, New Zealand, on 4 September 2010 and 22 February 2011 to demonstrate the varied conclusions that different recovery indicators can produce and to justify the need for a systematic approach to business recovery assessments. © 2018 The Author(s). Disasters © Overseas Development Institute, 2018.

Commodification and privacy: a Lockean perspective.

PubMed

Volkman, Richard

2010-09-01

This paper defends the thesis that privacy as a right is derived from fundamental rights to life, liberty, and property and does not permit restricting the commodification of bodily material; however, privacy as life, liberty, property does require conventions that ensure a robust and just market in bodily material. The analysis proceeds by defending a general commitment to liberty and markets, but not in the manner one might expect from a 'doctrinaire' libertarian. Ethical concerns about commodification are legitimate in the context of new medical and information technologies, but these concerns are not sufficiently well defined to justify political conclusions, since not every ethical concern is in itself a political concern, and the best way to resolve certain ethical difficulties is to draw up political boundaries that facilitate the discovery and testing of various solutions to our ethical puzzles. To illustrate the point, I will indicate how privacy as life, liberty, property defines such a dynamic solution to the problems of commodification of human bodily material and slippery information in insurance markets.

Extension and refinement of the predictive value of different classes of markers in ADNI: Four year follow-up data

PubMed Central

Gomar, Jesus J; Conejero-Goldberg, Concepcion; Davies, Peter; Goldberg, Terry E

2014-01-01

Background This study examined the predictive value of different classes of markers in the progression from Mild Cognitive Impairment (MCI) to Alzheimer’s disease (AD) over an extended 4 year follow-up in ADNI. Methods MCI patients assessed on clinical, cognitive, MRI, PET-FDG, and CSF markers at baseline, and followed on a yearly basis for four years to ascertain progression to AD. Logistic regression models were fitted in clusters including demographics, APOE genotype, cognitive markers, and biomarkers (morphometric, PET-FDG, CSF Abeta and tau). Results The predictive model at four years revealed that two cognitive measures, an episodic memory measure and a clock drawing screening test, were the best predictors of conversion (AUC= 0.78). Conclusions This model of prediction is consistent to the previous model at two years, thus highlighting the importance of cognitive measures in progression from MCI to AD. Cognitive markers were more robust predictors than biomarkers. PMID:24613706

Impact Evaluation of an Addiction Intervention Program in a Quebec Prison

PubMed Central

Arseneault, Catherine; Alain, Marc; Plourde, Chantal; Ferland, Francine; Blanchette-Martin, Nadine; Rousseau, Michel

2015-01-01

OBJECTIVES This study evaluates the effects of a prison-based addiction intervention program. The evaluation is based on a multidimensional data collection that draws a portrait of the respondents’ substance use, and of their psychological/emotional, social, and judicial spheres. It measures the changes, or lack thereof, in substance use; the psychological/emotional, social, and judicial spheres; as well as the post-treatment services used. METHOD A quasi-experimental repeated measures design (0, 6 weeks, and 6 months) was used. Effects of the program were identified by comparing the results obtained by a group of inmates who had participated in the program (n = 80; experimental group) with those of another group who had received no intervention (n = 70; control group). RESULTS The preliminary results suggested a certain treatment effect related to impulsivity and psychological distress. CONCLUSION Although the preliminary results were promising, the experimental and control groups did not differ significantly when more robust analyses were used. PMID:26056466

Complexity and robustness

PubMed Central

Carlson, J. M.; Doyle, John

2002-01-01

Highly optimized tolerance (HOT) was recently introduced as a conceptual framework to study fundamental aspects of complexity. HOT is motivated primarily by systems from biology and engineering and emphasizes, (i) highly structured, nongeneric, self-dissimilar internal configurations, and (ii) robust yet fragile external behavior. HOT claims these are the most important features of complexity and not accidents of evolution or artifices of engineering design but are inevitably intertwined and mutually reinforcing. In the spirit of this collection, our paper contrasts HOT with alternative perspectives on complexity, drawing on real-world examples and also model systems, particularly those from self-organized criticality. PMID:11875207

Optimized feature-detection for on-board vision-based surveillance

NASA Astrophysics Data System (ADS)

Gond, Laetitia; Monnin, David; Schneider, Armin

2012-06-01

The detection and matching of robust features in images is an important step in many computer vision applications. In this paper, the importance of the keypoint detection algorithms and their inherent parameters in the particular context of an image-based change detection system for IED detection is studied. Through extensive application-oriented experiments, we draw an evaluation and comparison of the most popular feature detectors proposed by the computer vision community. We analyze how to automatically adjust these algorithms to changing imaging conditions and suggest improvements in order to achieve more exibility and robustness in their practical implementation.

First-Pass Angiography in Mice Using FDG-PET: A Simple Method of Deriving the Cardiovascular Transit Time Without the Need of Region-of-Interest Drawing.

PubMed

Wu, Hsiao-Ming; Kreissl, Michael C; Schelbert, Heinrich R; Ladno, Waldemar; Prins, Mayumi; Shoghi-Jadid, Kooresh; Chatziioannou, Arion; Phelps, Michael E; Huang, Sung-Cheng

2005-10-01

In this study, we developed a simple and robust semi-automatic method to measure the right ventricle to left ventricle (RV-to-LV) transit time (TT) in mice using 2-[ 18 F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET). The accuracy of the method was first evaluated using a 4-D digital dynamic mouse phantom. The RV-to-LV TTs of twenty-nine mouse studies were measured using the new method and compared to those obtained from the conventional ROI-drawing method. The results showed that the new method correctly separated different structures (e.g., RV, lung, and LV) in the PET images and generated corresponding time activity curve (TAC) of each structure. The RV-to-LV TTs obtained from the new method and ROI method were not statistically different (P = 0.20; r = 0.76). We expect that this fast and robust method is applicable to the pathophysiology of cardiovascular diseases using small animal models such as rats and mice.

The DAB model of drawing processes

NASA Technical Reports Server (NTRS)

Hochhaus, Larry W.

1989-01-01

The problem of automatic drawing was investigated in two ways. First, a DAB model of drawing processes was introduced. DAB stands for three types of knowledge hypothesized to support drawing abilities, namely, Drawing Knowledge, Assimilated Knowledge, and Base Knowledge. Speculation concerning the content and character of each of these subsystems of the drawing process is introduced and the overall adequacy of the model is evaluated. Second, eight experts were each asked to understand six engineering drawings and to think aloud while doing so. It is anticipated that a concurrent protocol analysis of these interviews can be carried out in the future. Meanwhile, a general description of the videotape database is provided. In conclusion, the DAB model was praised as a worthwhile first step toward solution of a difficult problem, but was considered by and large inadequate to the challenge of automatic drawing. Suggestions for improvements on the model were made.

A novel knowledge-based system for interpreting complex engineering drawings: theory, representation, and implementation.

PubMed

Lu, Tong; Tai, Chiew-Lan; Yang, Huafei; Cai, Shijie

2009-08-01

We present a novel knowledge-based system to automatically convert real-life engineering drawings to content-oriented high-level descriptions. The proposed method essentially turns the complex interpretation process into two parts: knowledge representation and knowledge-based interpretation. We propose a new hierarchical descriptor-based knowledge representation method to organize the various types of engineering objects and their complex high-level relations. The descriptors are defined using an Extended Backus Naur Form (EBNF), facilitating modification and maintenance. When interpreting a set of related engineering drawings, the knowledge-based interpretation system first constructs an EBNF-tree from the knowledge representation file, then searches for potential engineering objects guided by a depth-first order of the nodes in the EBNF-tree. Experimental results and comparisons with other interpretation systems demonstrate that our knowledge-based system is accurate and robust for high-level interpretation of complex real-life engineering projects.

Side draw control design for a high purity multi-component distillation column.

PubMed

A Udugama, Isuru; Munir, M T; Kirkpatrick, Rob; Young, Brent R; Yu, Wei

2018-05-01

Industrial methanol production involves a multi component feed containing methanol, water and trace levels of ethanol being refined to produce AA grade methanol at high product recovery. Due to practical constraints, the bottoms discharge of the column is primarily water with only trace of methanol impurities. As a result of these constraints, ethanol, which is a non-key middle boiling component gets "trapped" near the side draw of the column forming an ethanol bulge, which in turn results in non-linear, inverse, time and state varying behaviour of the side draw ethanol composition. In this work, we established that the existence of the ethanol bulge creates the complex process behaviour of the side draw ethanol composition and that this bulge needs to be explicitly controlled. This type of explicit composition bulge analysis and subsequent control has not been attempted on methanol distillation columns before. For this purpose a novel, robust and practical side draw control scheme to detect and remedy the excess ethanol bulge movement using override control is presented. The side draw controller, together with other regulatory controllers is shown to maintain on-specification operations of the column. Disturbance rejection tests carried out illustrate that the side draw control scheme will keep the column operating within commercial specification. It is also shown that a traditional DV control structure is unable to achieve this objective. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

Evolutionary genetics of host shifts in herbivorous insects: insights from the age of genomics.

PubMed

Vertacnik, Kim L; Linnen, Catherine R

2017-02-01

Adaptation to different host taxa is a key driver of insect diversification. Herbivorous insects are classic models for ecological and evolutionary research, but it is recent advances in sequencing, statistics, and molecular technologies that have cleared the way for investigations into the proximate genetic mechanisms underlying host shifts. In this review, we discuss how genome-scale data are revealing-at resolutions previously unimaginable-the genetic architecture of host-use traits, the causal loci underlying host shifts, and the predictability of host-use evolution. Collectively, these studies are providing novel insights into longstanding questions about host-use evolution. On the basis of this synthesis, we suggest that different host-use traits are likely to differ in their genetic architecture (number of causal loci and the nature of their genetic correlations) and genetic predictability (extent of gene or mutation reuse), indicating that any conclusions about the causes and consequences of host-use evolution will depend heavily on which host-use traits are investigated. To draw robust conclusions and identify general patterns in host-use evolution, we argue that investigation of diverse host-use traits and identification of causal genes and mutations should be the top priorities for future studies on the evolutionary genetics of host shifts. © 2017 New York Academy of Sciences.

Students Selling Sex: Marketisation, Higher Education and Consumption

ERIC Educational Resources Information Center

Sanders, Teela; Hardy, Kate

2015-01-01

Robust academic research on the topic of students involved in the sex industry is in its infancy, yet the relationship appears consistent and permanent. This paper draws on findings from the largest study into the stripping industry in the United Kingdom to explore the relationships between students, sex work and consumption. To make sense of the…

Topographic Maps: Rediscovering an Accessible Data Source for Land Cover Change Research

ERIC Educational Resources Information Center

McChesney, Ron; McSweeney, Kendra

2005-01-01

Given some limitations of satellite imagery for the study of land cover change, we draw attention here to a robust and often overlooked data source for use in student research: USGS topographic maps. Topographic maps offer an inexpensive, rapid, and accessible means for students to analyze land cover change over large areas. We demonstrate our…

Higher Education in England 2016: Key Facts. September 2016/20

ERIC Educational Resources Information Center

Higher Education Funding Council for England, 2016

2016-01-01

This updated edition of "Higher Education in England: Key Facts" provides a statistical overview of key sector trends and developments in 2016. Using the most recent data, it draws together key findings from a range of reports published by the Higher Education Funding Council for England (HEFCE) over the past year to provide a robust,…

Experimental Estimates of the Impacts of Class Size on Test Scores: Robustness and Heterogeneity

ERIC Educational Resources Information Center

Ding, Weili; Lehrer, Steven F.

2011-01-01

Proponents of class size reductions (CSRs) draw heavily on the results from Project Student/Teacher Achievement Ratio to support their initiatives. Adding to the political appeal of these initiative are reports that minority and economically disadvantaged students received the largest benefits from smaller classes. We extend this research in two…

Drawing in nursing PBL.

PubMed

Chan, Zenobia C Y

2013-08-01

The implementation of art education in nursing is said to have positive effects on nursing students. Most studies applied visual art dialogues or object design, whereas the effectiveness of drawing as a teaching and learning method is rarely examined and discussed. This paper aimed to discuss the potential and effectiveness of drawing as a learning and teaching method. Four drawings which were created by Hong Kong nursing students are demonstrated and the students' perspectives of how drawing enhanced learning are shown in this paper. Topics on drawing as a fun teaching and learning method and the way it can enhance critical thinking and creativity are also discussed. In conclusion, the activity was a great success, and students enjoyed the learning process and reflected positive comments. However, we cannot conclude that drawing is an effective teaching and learning method based on a single paper, therefore more similar studies should be conducted to investigate this method. Copyright © 2012 Elsevier Ltd. All rights reserved.

Fructose, high-fructose corn syrup, sucrose, and nonalcoholic fatty liver disease or indexes of liver health: a systematic review and meta-analysis.

PubMed

Chung, Mei; Ma, Jiantao; Patel, Kamal; Berger, Samantha; Lau, Joseph; Lichtenstein, Alice H

2014-09-01

Concerns have been raised about the concurrent temporal trend between simple sugar intakes, especially of fructose or high-fructose corn syrup (HFCS), and rates of nonalcoholic fatty liver disease (NAFLD) in the United States. We examined the effect of different amounts and forms of dietary fructose on the incidence or prevalence of NAFLD and indexes of liver health in humans. We conducted a systematic review of English-language, human studies of any design in children and adults with low to no alcohol intake and that reported at least one predetermined measure of liver health. The strength of the evidence was evaluated by considering risk of bias, consistency, directness, and precision. Six observational studies and 21 intervention studies met the inclusion criteria. The overall strength of evidence for observational studies was rated insufficient because of high risk of biases and inconsistent study findings. Of 21 intervention studies, 19 studies were in adults without NAFLD (predominantly healthy, young men) and 1 study each in adults or children with NAFLD. We found a low level of evidence that a hypercaloric fructose diet (supplemented by pure fructose) increases liver fat and aspartate aminotransferase (AST) concentrations in healthy men compared with the consumption of a weight-maintenance diet. In addition, there was a low level of evidence that hypercaloric fructose and glucose diets have similar effects on liver fat and liver enzymes in healthy adults. There was insufficient evidence to draw a conclusion for effects of HFCS or sucrose on NAFLD. On the basis of indirect comparisons across study findings, the apparent association between indexes of liver health (ie, liver fat, hepatic de novo lipogenesis, alanine aminotransferase, AST, and γ-glutamyl transpeptase) and fructose or sucrose intake appear to be confounded by excessive energy intake. Overall, the available evidence is not sufficiently robust to draw conclusions regarding effects of fructose, HFCS, or sucrose consumption on NAFLD. © 2014 American Society for Nutrition.

Body image drawings dissociate ethnic differences and anorexia in adolescent girls.

PubMed

Goldzak-Kunik, Galit; Leshem, Micah

2017-01-01

To distinguish between ethnic differences among segregated schoolgirls and restrictive anorexia nervosa using a simple culture-fair test of body image (BI) figure drawings. Several responses to BI figure drawings by 178 adolescent schoolgirls from three ethnically distinct and segregated schools and communities in Israel, Jewish secular (JS), Jewish Haredi (H), and Christian Arab (C), and a group of 14 severely restricting anorexic girls (AN). BI evaluations were analyzed by MANCOVA, followed by paired or Student-t tests for comparisons between responses and groups respectively. Pearson r served for correlations and the Fisher Z for differences between slopes. Despite the total ethnic segregation among the schoolgirls, there are commonalities; all prefer a thinner ideal BI, and are similarly dissatisfied with their BI. However, ethnic differences also emerge: C underestimate their BI and how others view them, and H true and Ideal BI evaluations correlate, unlike the other groups. Despite this variability, and in stark contrast, the anorexic girls show a gross misperception of their BI, even in comparison to girls equated for BMI. The findings show that figure drawings evaluation of BI is a simple and robust instrument dissociating clinical and ethnic responses. Clinicians may consider body figure drawings as a simple, supportive, diagnostic for first-line recognition for risk of AN in adolescent girls.

Hybrid approach for robust diagnostics of cutting tools

NASA Astrophysics Data System (ADS)

Ramamurthi, K.; Hough, C. L., Jr.

1994-03-01

A new multisensor based hybrid technique has been developed for robust diagnosis of cutting tools. The technique combines the concepts of pattern classification and real-time knowledge based systems (RTKBS) and draws upon their strengths; learning facility in the case of pattern classification and a higher level of reasoning in the case of RTKBS. It eliminates some of their major drawbacks: false alarms or delayed/lack of diagnosis in case of pattern classification and tedious knowledge base generation in case of RTKBS. It utilizes a dynamic distance classifier, developed upon a new separability criterion and a new definition of robust diagnosis for achieving these benefits. The promise of this technique has been proven concretely through an on-line diagnosis of drill wear. Its suitability for practical implementation is substantiated by the use of practical, inexpensive, machine-mounted sensors and low-cost delivery systems.

Response to Taguchi and Noma on "relationship between directionality and orientation in drawings by young children and adults.

PubMed

Karev, George B

2006-02-01

When assessing the relationship between direction and orientation in drawings by young children and adults, Taguchi and Noma used a fish-drawing task. However, the fish is not convenient enough as an object for such a task so it is highly preferable to use, instead of a single object, a set of several objects to assess directionality quantitatively. These authors' conclusions do not acknowledge alternative explanations.

Why Save a Can?

ERIC Educational Resources Information Center

Gutierrez, Melida; Johnson, Cheryl

2009-01-01

This activity ties together the recycling of aluminum and the protection of rain forests. Students use critical thinking to study the effects of open pit mining of bauxite in rain forests and then draw their own conclusions about how to minimize the impact of bauxite mining and boost recycling efforts within their communities. Drawing conclusions…

Family and Teacher Characteristics as Predictors of Parent Involvement in Education during Early Childhood among Afro-Caribbean and Latino Immigrant Families

ERIC Educational Resources Information Center

Calzada, Esther J.; Huang, Keng-Yen; Hernandez, Miguel; Soriano, Erika; Acra, C. Francoise; Dawson-McClure, Spring; Kamboukos, Dimitra; Brotman, Laurie

2015-01-01

Parent involvement is a robust predictor of academic achievement, but little is known about school- and home-based involvement in immigrant families. Drawing on ecological theories, the present study examined contextual characteristics as predictors of parent involvement among Afro-Caribbean and Latino parents of young students in urban public…

Outlook for Mississippi Alluvial Valley forests: a subregional report from the Southern Forest Futures Project

Treesearch

Emile S. Gardiner

2015-01-01

The Mississippi Alluvial Valley, which can be broadly subdivided into the Holocene Deposits section and the Deltaic Plain section, is a 24.9-million-acre area generally approximating the alluvial floodplain and delta of the lower Mississippi River. Its robust agricultural economy is maintained by a largely rural population, and recreational resources draw high...

Seven "Chilis": Making Visible the Complexities in Leveraging Cultural Repertories of Practice in a Designed Teaching and Learning Environment

ERIC Educational Resources Information Center

DiGiacomo, Daniela Kruel; Gutiérrez, Kris D.

2017-01-01

Drawing upon four years of research within a social design experiment, we focus on how teacher learning can be supported in designed environments that are organized around robust views of learning, culture, and equity. We illustrate both the possibility and difficulty of helping teachers disrupt the default teaching scripts that privilege…

From a Language to a Theory of Resistance: Critical Pedagogy, the Limits of "Framing," and Social Change

ERIC Educational Resources Information Center

Tarlau, Rebecca

2014-01-01

In this article, Rebecca Tarlau attempts to build a more robust theory of the relationship between education and social change by drawing on the conceptual tools offered in the critical pedagogy and social movement literatures. Tarlau argues that while critical pedagogy has been largely disconnected from its roots in political organizing, social…

Good Practices for Student Learning: Mixed-Method Evidence from the Wabash National Study

ERIC Educational Resources Information Center

Goodman, Kathleen M.; Magolda, Marcia Baxter; Seifert, Tricia A.; King, Patricia M.

2011-01-01

Since 2006, 19 institutions across the United States have been trying to figure out how to work smarter through their participation in the Wabash National Study of Liberal Arts Education. Drawing on data from the first year of the study, the robust, mixed-methods study the authors report in this article evaluated growth in the first year of…

How to Plan Rigorous Instruction. Mastering the Principles of Great Teaching Series

ERIC Educational Resources Information Center

Jackson, Robyn R.

2010-01-01

What if you could go beyond planning and delivering tightly scripted lessons mapped to a standardized test to facilitating rich, robust learning experiences that prepare students to be critical thinkers and lifelong learners? The good news is that you can do it all when you have the steps and strategies from this guide. Drawing from the principles…

Variation in reaction norms: Statistical considerations and biological interpretation.

PubMed

Morrissey, Michael B; Liefting, Maartje

2016-09-01

Analysis of reaction norms, the functions by which the phenotype produced by a given genotype depends on the environment, is critical to studying many aspects of phenotypic evolution. Different techniques are available for quantifying different aspects of reaction norm variation. We examine what biological inferences can be drawn from some of the more readily applicable analyses for studying reaction norms. We adopt a strongly biologically motivated view, but draw on statistical theory to highlight strengths and drawbacks of different techniques. In particular, consideration of some formal statistical theory leads to revision of some recently, and forcefully, advocated opinions on reaction norm analysis. We clarify what simple analysis of the slope between mean phenotype in two environments can tell us about reaction norms, explore the conditions under which polynomial regression can provide robust inferences about reaction norm shape, and explore how different existing approaches may be used to draw inferences about variation in reaction norm shape. We show how mixed model-based approaches can provide more robust inferences than more commonly used multistep statistical approaches, and derive new metrics of the relative importance of variation in reaction norm intercepts, slopes, and curvatures. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

Robustness of movement models: can models bridge the gap between temporal scales of data sets and behavioural processes?

PubMed

Schlägel, Ulrike E; Lewis, Mark A

2016-12-01

Discrete-time random walks and their extensions are common tools for analyzing animal movement data. In these analyses, resolution of temporal discretization is a critical feature. Ideally, a model both mirrors the relevant temporal scale of the biological process of interest and matches the data sampling rate. Challenges arise when resolution of data is too coarse due to technological constraints, or when we wish to extrapolate results or compare results obtained from data with different resolutions. Drawing loosely on the concept of robustness in statistics, we propose a rigorous mathematical framework for studying movement models' robustness against changes in temporal resolution. In this framework, we define varying levels of robustness as formal model properties, focusing on random walk models with spatially-explicit component. With the new framework, we can investigate whether models can validly be applied to data across varying temporal resolutions and how we can account for these different resolutions in statistical inference results. We apply the new framework to movement-based resource selection models, demonstrating both analytical and numerical calculations, as well as a Monte Carlo simulation approach. While exact robustness is rare, the concept of approximate robustness provides a promising new direction for analyzing movement models.

Psychological Distress and Drawing Tests among Women with Breast Cancer

PubMed Central

2018-01-01

Background The aim of this study was to evaluate the use of the Diagnostic Drawing Series (DDS) as a screening tool for the breast cancer patients with psychological distress. Methods All of 64 patients with breast cancer participated in this study. Patients' depressive and anxiety symptoms were assessed using Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) when the DDS was applied to the partipicants. Results Depressed patients used more enclosure in the Feeling drawings (P = 0.002) and tilt in Free drawings (P = 0.048). Patients with anxiety drew a picture over 67% of the paper (P = 0.015) in Tree drawing and more medium pressure (P = 0.049) in Feeling drawings. Thirty four subjects (77.3%) of unstable emotion group used over 67% of the space (P = 0.002). More Landscapes were observed in the Feeling drawings of unstable patients (P = 0.042). Conclusion These results suggested that DDS could be used as a supplemental screening tool for psychological distress in breast cancer patients. PMID:29686600

Brief report: new evidence for a social-specific imagination deficit in children with autism spectrum disorder.

PubMed

Ten Eycke, Kayla D; Müller, Ulrich

2015-01-01

Previous research suggests that children with autism have deficits in drawing imaginative content. However, these conclusions are largely based on tasks that require children to draw impossible persons, and performance on this task may be limited by social deficits. To determine the generality of the deficit in imagination in children with autism, we asked 25 children with autism (mean age 9;7) and 29 neurotypically developing children (mean age 8;7) to draw an imaginative person and house. Drawings of imaginary houses by children with autism did not differ from those by neurotypically developing controls, but drawings of persons were significantly less imaginative. These findings suggest that the impairment in imagination among children with autism may be specific to social stimuli.

The “Face” of Diabetes

PubMed Central

Liesch, Shari K; Babler, Elizabeth K

2016-01-01

Objective: The purpose of this descriptive pilot study was to assess the ability of youth to create a meaningful drawing related to living with type 1 diabetes and explore the benefits of expressing emotion through drawing in future interventional work. Methods: Youth aged 4 to 19 years (N = 242) with type I diabetes attending routine follow-up appointments within a pediatric specialty clinic were asked to draw: “If diabetes had a face what would it look like?” Results: Drawings reflected many emotions and ranged from simple to complex in detail. Drawings reflected multiple experiences of living with diabetes including emotions, tools used for management, and effects of self-care. Conclusions: Youth were able to create drawings reflecting their experience of living with diabetes. Youth conveyed a variety of emotions, attitudes, and experiences in drawing the “face” of diabetes. Drawing during clinic visits provides opportunity to explore the unspoken experiences of living with a chronic health condition, which may not be obtained during routine clinical information gathering. Deeper understanding of patient’s lived experience may assist providers in therapeutic management. PMID:28725833

Seizure drawings: insight into the self-image of children with epilepsy.

PubMed

Stafstrom, Carl E; Havlena, Janice

2003-02-01

Epilepsy is a chronic disorder that is associated with numerous psychological challenges, especially in children. Drawings have been underutilized as a method to obtain insight into psychological issues in children with epilepsy. We asked 105 children with epilepsy, ages 5 to 18 years, to draw a picture of what it is like to have a seizure. Across ages and epilepsy syndromes, the drawings showed evidence of impaired self-concept, low self-esteem, and a sense of helplessness and vulnerability. Overall, the drawings of human figures were less developed than expected for chronological age. In some drawings, indicators of underlying depression were found. When considered by epilepsy syndrome or seizure type, some specific artistic features were noted. Children with simple partial (motor) seizures drew distorted body parts, especially limbs. Those with complex partial seizures depicted sensory symptoms and mental status changes such as confusion. Children with generalized tonic-clonic seizures showed shaking extremities. Drawings by children with absence seizures illustrated mainly staring. In conclusion, drawings are a powerful method to examine the self-concept of children with epilepsy and gain insight into their feelings about themselves and their world.

Computerized Spiral Analysis Using the iPad

PubMed Central

Sisti, Jonathan A.; Christophe, Brandon; Seville, Audrey Rakovich; Garton, Andrew L.A.; Gupta, Vivek P.; Bandin, Alexander J.; Yu, Qiping; Pullman, Seth L.

2017-01-01

Background Digital analysis of writing and drawing has become a valuable research and clinical tool for the study of upper limb motor dysfunction in patients with essential tremor, Parkinson’s disease, dystonia, and related disorders. We developed a validated method of computerized spiral analysis of hand-drawn Archimedean spirals that provides insight into movement dynamics beyond subjective visual assessment using a Wacom graphics tablet. While the Wacom tablet method provides robust data, more widely available mobile technology platforms exist. New Method We introduce a novel adaptation of the Wacom-based method for the collection of hand-drawn kinematic data using an Apple iPad. This iPad-based system is stand-alone, easy-to-use, can capture drawing data with either a finger or capacitive stylus, is precise, and potentially ubiquitous. Results The iPad-based system acquires position and time data that is fully compatible with our original spiral analysis program. All of the important indices including degree of severity, speed, presence of tremor, tremor amplitude, tremor frequency, variability of pressure, and tightness are calculated from the digital spiral data, which the application is able to transmit. Comparison with Existing Method While the iPad method is limited by current touch screen technology, it does collect data with acceptable congruence compared to the current Wacom-based method while providing the advantages of accessibility and ease of use. Conclusions The iPad is capable of capturing precise digital spiral data for analysis of motor dysfunction while also providing a convenient, easy-to-use modality in clinics and potentially at home. PMID:27840146

Standardisation in the field of nanotechnology: some issues of legitimacy.

PubMed

Forsberg, Ellen-Marie

2012-12-01

Nanotechnology will allegedly have a revolutionary impact in a wide range of fields, but has also created novel concerns about health, safety and the environment (HSE). Nanotechnology regulation has nevertheless lagged behind nanotechnology development. In 2004 the International Organization for Standardization established a technical committee for producing nanotechnology standards for terminology, measurements, HSE issues and product specifications. These standards are meant to play a role in nanotechnology development, as well as in national and international nanotechnology regulation, and will therefore have consequences for consumers, workers and the environment. This paper gives an overview of the work in the technical committee on nanotechnology and discusses some challenges with regard to legitimacy in such work. The paper focuses particularly on stakeholder involvement and the potential problems of scientific robustness when standardising in such early stages of the scientific development. The intention of the paper is to raise some important issues rather than to draw strong conclusions. However, the paper will be concluded with some suggestions for improving legitimacy in the TC 229 and a call for increased public awareness about standardisation in the field of nanotechnology.

Robust misinterpretation of confidence intervals.

PubMed

Hoekstra, Rink; Morey, Richard D; Rouder, Jeffrey N; Wagenmakers, Eric-Jan

2014-10-01

Null hypothesis significance testing (NHST) is undoubtedly the most common inferential technique used to justify claims in the social sciences. However, even staunch defenders of NHST agree that its outcomes are often misinterpreted. Confidence intervals (CIs) have frequently been proposed as a more useful alternative to NHST, and their use is strongly encouraged in the APA Manual. Nevertheless, little is known about how researchers interpret CIs. In this study, 120 researchers and 442 students-all in the field of psychology-were asked to assess the truth value of six particular statements involving different interpretations of a CI. Although all six statements were false, both researchers and students endorsed, on average, more than three statements, indicating a gross misunderstanding of CIs. Self-declared experience with statistics was not related to researchers' performance, and, even more surprisingly, researchers hardly outperformed the students, even though the students had not received any education on statistical inference whatsoever. Our findings suggest that many researchers do not know the correct interpretation of a CI. The misunderstandings surrounding p-values and CIs are particularly unfortunate because they constitute the main tools by which psychologists draw conclusions from data.

Sunyaev–Zel’Dovich Signal from Quasar Hosts: Implications for Detection of Quasar Feedback

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chowdhury, Dhruba Dutta; Chatterjee, Suchetana, E-mail: dhruba.duttachowdhury@yale.edu

2017-04-10

Several analytic and numerical studies have indicated that the interstellar medium of a quasar host galaxy heated by feedback can contribute to a substantial secondary signal in the cosmic microwave background (CMB) through the thermal Sunyaev–Zel’dovich (SZ) effect. Recently, many groups have tried to detect this signal by cross-correlating CMB maps with quasar catalogs. Using a self-similar model for the gas in the intra-cluster medium and a realistic halo occupation distribution (HOD) prescription for quasars, we estimate the level of SZ signal from gravitational heating of quasar hosts. The bias in the host halo signal estimation due to an unconstrainedmore » high mass HOD tail and yet unknown redshift dependence of the quasar HOD restricts us from drawing any robust conclusions at low redshift ( z < 1.5) from our analysis. However, at higher redshifts ( z > 2.5), we find an excess signal in recent observations than what is predicted from our model. The excess signal could be potentially generated from additional heating due to quasar feedback.« less

Public health benefits of strategies to reduce greenhouse-gas emissions: health implications of short-lived greenhouse pollutants.

PubMed

Smith, Kirk R; Jerrett, Michael; Anderson, H Ross; Burnett, Richard T; Stone, Vicki; Derwent, Richard; Atkinson, Richard W; Cohen, Aaron; Shonkoff, Seth B; Krewski, Daniel; Pope, C Arden; Thun, Michael J; Thurston, George

2009-12-19

In this report we review the health effects of three short-lived greenhouse pollutants-black carbon, ozone, and sulphates. We undertook new meta-analyses of existing time-series studies and an analysis of a cohort of 352,000 people in 66 US cities during 18 years of follow-up. This cohort study provides estimates of mortality effects from long-term exposure to elemental carbon, an indicator of black carbon mass, and evidence that ozone exerts an independent risk of mortality. Associations among these pollutants make drawing conclusions about their individual health effects difficult at present, but sulphate seems to have the most robust effects in multiple-pollutant models. Generally, the toxicology of the pure compounds and their epidemiology diverge because atmospheric black carbon, ozone, and sulphate are associated and could interact with related toxic species. Although sulphate is a cooling agent, black carbon and ozone could together exert nearly half as much global warming as carbon dioxide. The complexity of these health and climate effects needs to be recognised in mitigation policies. Copyright 2009 Elsevier Ltd. All rights reserved.

[Incidence of endophthalmitis after intravitreal injection: is antibioprophylaxis mandatory?].

PubMed

Ramel, J-C; Bron, A-M; Isaico, R; Meillon, C; Binquet, C; Creuzot-Garcher, C

2014-04-01

Endophthalmitis is the most dreaded complication after intravitreal injection. With the rise of antiangiogenics their rate is getting higher each year. The use of antibioprophylaxis is controversial. We tried to evaluate the impact of antibioprophylaxis on intravitreal injection endophthalmitis incidence. All patients who received intravitreal injections between January 2007 and October 2012 were included in this retrospective study. Until June 2012 all patients had antibiotics the days following the injection. From July 2012 the antibiotic was replaced by an antiseptic immediately after the injection. An overall number of 11,450 injections were performed. The overall rate of endophthalmitis was 6/11,450 (0.052%). The incidence of endophthalmitis in the group with antibiotics was 3/10,144 injections (0.03%), 2 were culture proven (0.02%). The incidence in the group without antibiotics was 3/1306 (0.23%). The difference was significant (P=0.024). The incidence of endophthalmitis post-intravitreal injections seems to be lower when using antibiotics. However, a prospective study is mandatory to draw more robust conclusions. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Multigrid solution of the Navier-Stokes equations on highly stretched grids with defect correction

NASA Technical Reports Server (NTRS)

Sockol, Peter M.

1993-01-01

Relaxation-based multigrid solvers for the steady incompressible Navier-Stokes equations are examined to determine their computational speed and robustness. Four relaxation methods with a common discretization have been used as smoothers in a single tailored multigrid procedure. The equations are discretized on a staggered grid with first order upwind used for convection in the relaxation process on all grids and defect correction to second order central on the fine grid introduced once per multigrid cycle. A fixed W(1,1) cycle with full weighting of residuals is used in the FAS multigrid process. The resulting solvers have been applied to three 2D flow problems, over a range of Reynolds numbers, on both uniform and highly stretched grids. In all cases the L(sub 2) norm of the velocity changes is reduced to 10(exp -6) in a few 10's of fine grid sweeps. The results from this study are used to draw conclusions on the strengths and weaknesses of the individual relaxation schemes as well as those of the overall multigrid procedure when used as a solver on highly stretched grids.

Shaping the future of nursing: developing an appraisal framework for public engagement with nursing policy reports.

PubMed

Bradshaw, Ann

2015-03-01

It is accepted that research should be systematically examined to judge its trustworthiness and value in a particular context. No such appraisal is required of reports published by organizations that have possibly even greater influence on policy that affects the public. This paper explores a philosophical framework for appraising reports. It gives the reasons why informed engagement is important, drawing on Popper's concept of the open society, and it suggests a method for appraisal. Gadamer's concept of the two horizons and Jauss's reception theory offer a methodological framework to enable the individual citizen, whether professional or lay, to engage in debate about policy that affects him or her. By way of a worked example, the framework is applied to two international reports on nursing. Conclusions suggest that nursing policy should be subjected to robust interrogatory appraisal by both profession and public for a democratic debate and creative discourse. Although this analysis is related to international nursing policy, it has a wider relevance and application beyond nursing. © 2014 John Wiley & Sons Ltd.

Corticosteroids for severe influenza pneumonia: A critical appraisal

PubMed Central

Nedel, Wagner Luis; Nora, David Garcia; Salluh, Jorge Ibrain Figueira; Lisboa, Thiago; Póvoa, Pedro

2016-01-01

Influenza pneumonia is associated with high number of severe cases requiring hospital and intensive care unit (ICU) admissions with high mortality. Systemic steroids are proposed as a valid therapeutic option even though its effects are still controversial. Heterogeneity of published data regarding study design, population demographics, severity of illness, dosing, type and timing of corticosteroids administered constitute an important limitation for drawing robust conclusions. However, it is reasonable to admit that, as it was not found any advantage of corticosteroid therapy in so diverse conditions, such beneficial effects do not exist at all. Its administration is likely to increase overall mortality and such trend is consistent regardless of the quality as well as the sample size of studies. Moreover it was shown that corticosteroids might be associated with higher incidence of hospital-acquired pneumonia and longer duration of mechanical ventilation and ICU stay. Finally, it is reasonable to conclude that corticosteroids failed to demonstrate any beneficial effects in the treatment of patients with severe influenza infection. Thus its current use in severe influenza pneumonia should be restricted to very selected cases and in the setting of clinical trials. PMID:26855898

Environmental changes and violent conflict

NASA Astrophysics Data System (ADS)

Bernauer, Thomas; Böhmelt, Tobias; Koubi, Vally

2012-03-01

This letter reviews the scientific literature on whether and how environmental changes affect the risk of violent conflict. The available evidence from qualitative case studies indicates that environmental stress can contribute to violent conflict in some specific cases. Results from quantitative large-N studies, however, strongly suggest that we should be careful in drawing general conclusions. Those large-N studies that we regard as the most sophisticated ones obtain results that are not robust to alternative model specifications and, thus, have been debated. This suggests that environmental changes may, under specific circumstances, increase the risk of violent conflict, but not necessarily in a systematic way and unconditionally. Hence there is, to date, no scientific consensus on the impact of environmental changes on violent conflict. This letter also highlights the most important challenges for further research on the subject. One of the key issues is that the effects of environmental changes on violent conflict are likely to be contingent on a set of economic and political conditions that determine adaptation capacity. In the authors' view, the most important indirect effects are likely to lead from environmental changes via economic performance and migration to violent conflict.

Public health benefits of strategies to reduce greenhouse-gas emissions: health implications of short-lived greenhouse pollutants

PubMed Central

Smith, Kirk R.; Jerrett, Michael; Anderson, H Ross; Burnett, Richard T.; Stone, Vicki; Derwent, Richard; Atkinson, Richard W.; Cohen, Aaron; Shonkoff, Seth B.; Krewski, Daniel; Pope, C. Arden; Thun, Michael J.; Thurston, George

2014-01-01

In this report we review the health effects of three short-lived greenhouse pollutants—black carbon, ozone, and sulphates. We undertook new meta-analyses of existing time-series studies and an analysis of a cohort of 352 000 people in 66 US cities during 18 years of follow-up. This cohort study provides estimates of mortality effects from long-term exposure to elemental carbon, an indicator of black carbon mass, and evidence that ozone exerts an independent risk of mortality. Associations among these pollutants make drawing conclusions about their individual health effects difficult at present, but sulphate seems to have the most robust effects in multiple-pollutant models. Generally, the toxicology of the pure compounds and their epidemiology diverge because atmospheric black carbon, ozone, and sulphate are associated and could interact with related toxic species. Although sulphate is a cooling agent, black carbon and ozone could together exert nearly half as much global warming as carbon dioxide. The complexity of these health and climate effects needs to be recognised in mitigation policies. PMID:19942276

What's behind the Name? The Intensification of Co-Branding in Elite US Colleges of Business and Education

ERIC Educational Resources Information Center

Mars, Matthew M.

2010-01-01

This article presents research that draws attention to the intensification of co-branding within elite US graduate colleges of business and education. A robust set of descriptive data collected and analyzed according to a content analysis strategy is used to develop an initial understanding of the trend of naming of colleges and academic units in…

Guide to NavyFOAM V1.0

DTIC Science & Technology

2011-04-01

NavyFOAM has been developed using an open-source CFD software tool-kit ( OpenFOAM ) that draws heavily upon object-oriented programming. The...numerical methods and the physical models in the original version of OpenFOAM have been upgraded in an effort to improve accuracy and robustness of...computational fluid dynamics OpenFOAM , Object Oriented Programming (OOP) (CFD), NavyFOAM, 16. SECURITY CLASSIFICATION OF: a. REPORT UNCLASSIFIED b

Drawing Firmer Conclusions: Autistic Children Show No Evidence of a Local Processing Bias in a Controlled Copying Task

ERIC Educational Resources Information Center

Smith, Alastair D.; Kenny, Lorcan; Rudnicka, Anna; Briscoe, Josie; Pellicano, Elizabeth

2016-01-01

Drawing tasks are frequently used to test competing theories of visuospatial skills in autism. Yet, methodological differences between studies have led to inconsistent findings. To distinguish between accounts based on local bias or global deficit, we present a simple task that has previously revealed dissociable local/global impairments in…

Online Emotional Inferences in Written and Auditory Texts: A Study with Children and Adults

ERIC Educational Resources Information Center

Diergarten, Anna Katharina; Nieding, Gerhild

2016-01-01

Emotional inferences are conclusions that a reader draws about the emotional state of a story's protagonist. In this study, we examined whether children and adults draw emotional inferences while reading short stories or listening to an aural presentation of short stories. We used an online method that assesses inferences during reading with a…

Robustness trade-offs and host–microbial symbiosis in the immune system

PubMed Central

Kitano, Hiroaki; Oda, Kanae

2006-01-01

The immune system provides organisms with robustness against pathogen threats, yet it also often adversely affects the organism as in autoimmune diseases. Recently, the molecular interactions involved in the immune system have been uncovered. At the same time, the role of the bacterial flora and its interactions with the host immune system have been identified. In this article, we try to reconcile these findings to draw a consistent picture of the host defense system. Specifically, we first argue that the network of molecular interactions involved in immune functions has a bow-tie architecture that entails inherent trade-offs among robustness, fragility, resource limitation, and performance. Second, we discuss the possibility that commensal bacteria and the host immune system constitute an integrated defense system. This symbiotic association has evolved to optimize its robustness against pathogen attacks and nutrient perturbations by harboring a broad range of microorganisms. Owing to the inherent propensity of a host immune system toward hyperactivity, maintenance of bacterial flora homeostasis might be particularly important in the development of preventive strategies against immune disorders such as autoimmune diseases. PMID:16738567

L1C signal design options

USGS Publications Warehouse

Betz, J.W.; Cahn, C.R.; Dafesh, P.A.; Hegarty, C.J.; Hudnut, K.W.; Jones, A.J.; Keegan, R.; Kovach, K.; Lenahan, L.S.; Ma, H.H.; Rushanan, J.J.; Stansell, T.A.; Wang, C.C.; Yi, S.K.

2006-01-01

Design activities for a new civil signal centered at 1575.42 MHz, called L1C, began in 2003, and the Phase 1 effort was completed in 2004. The L1C signal design has evolved and matured during a Phase 2 design activity that began in 2005. Phase 2 has built on the initial design activity, guided by responses to international user surveys conducted during Phase 1. A common core of signal characteristics has been developed to provide advances in robustness and performance. The Phase 2 activity produced five design options, all drawing upon the core signal characteristics, while representing different blends of characteristics and capabilities. A second round of international user surveys was completed to solicit advice concerning these design options. This paper provides an update of the L1C design process, and describes the current L1C design options. Initial performance estimates are presented for each design option, displaying trades between signal tracking robustness, the speed and robustness of clock and ephemeris data, and the rate and robustness of other data message contents. Planned remaining activities are summarized, leading to optimization of the L1C design.

The role of effective connectivity between the task-positive and task-negative network for evidence gathering [Evidence gathering and connectivity].

PubMed

Andreou, Christina; Steinmann, Saskia; Kolbeck, Katharina; Rauh, Jonas; Leicht, Gregor; Moritz, Steffen; Mulert, Christoph

2018-06-01

Reports linking a 'jumping-to-conclusions' bias to delusions have led to growing interest in the neurobiological correlates of probabilistic reasoning. Several brain areas have been implicated in probabilistic reasoning; however, findings are difficult to integrate into a coherent account. The present study aimed to provide additional evidence by investigating, for the first time, effective connectivity among brain areas involved in different stages of evidence gathering. We investigated evidence gathering in 25 healthy individuals using fMRI and a new paradigm (Box Task) designed such as to minimize the effects of cognitive effort and reward processing. Decisions to collect more evidence ('draws') were contrasted to decisions to reach a final choice ('conclusions') with respect to BOLD activity. Psychophysiological interaction analysis was used to investigate effective connectivity. Conclusion events were associated with extensive brain activations in widely distributed brain areas associated with the task-positive network. In contrast, draw events were characterized by higher activation in areas assumed to be part of the task-negative network. Effective connectivity between the two networks decreased during draws and increased during conclusion events. Our findings indicate that probabilistic reasoning may depend on the balance between the task-positive and task-negative network, and that shifts in connectivity between the two may be crucial for evidence gathering. Thus, abnormal connectivity between the two systems may significantly contribute to the jumping-to-conclusions bias. Copyright © 2018 Elsevier Inc. All rights reserved.

Robust Planning for Effects-Based Operations

DTIC Science & Technology

2006-06-01

Algorithm ......................................... 34 2.6 Robust Optimization Literature ..................................... 36 2.6.1 Protecting Against...Model Formulation ...................... 55 3.1.5 Deterministic EBO Model Example and Performance ............. 59 3.1.6 Greedy Algorithm ...111 4.1.9 Conclusions on Robust EBO Model Performance .................... 116 4.2 Greedy Algorithm versus EBO Models

Brief Report: New Evidence for a Social-Specific Imagination Deficit in Children with Autism Spectrum Disorder

ERIC Educational Resources Information Center

Ten Eycke, Kayla D.; Müller, Ulrich

2015-01-01

Previous research suggests that children with autism have deficits in drawing imaginative content. However, these conclusions are largely based on tasks that require children to draw impossible persons, and performance on this task may be limited by social deficits. To determine the generality of the deficit in imagination in children with autism,…

Picturing Obama: Race, High School Students and a Critical Methodology of the Visual

ERIC Educational Resources Information Center

Smith, William L.

2017-01-01

I draw on methodological findings from a case study on how high school students of color make sense of dominant narratives of race and politics in the Obama American Era. Incorporating literature from critical race theory, visual research methods, and the writings of cultural scholar Stuart Hall, I draw conclusions from this inquiry project as a…

The genesis of errors in drawing.

PubMed

Chamberlain, Rebecca; Wagemans, Johan

2016-06-01

The difficulty adults find in drawing objects or scenes from real life is puzzling, assuming that there are few gross individual differences in the phenomenology of visual scenes and in fine motor control in the neurologically healthy population. A review of research concerning the perceptual, motoric and memorial correlates of drawing ability was conducted in order to understand why most adults err when trying to produce faithful representations of objects and scenes. The findings reveal that accurate perception of the subject and of the drawing is at the heart of drawing proficiency, although not to the extent that drawing skill elicits fundamental changes in visual perception. Instead, the decisive role of representational decisions reveals the importance of appropriate segmentation of the visual scene and of the influence of pictorial schemas. This leads to the conclusion that domain-specific, flexible, top-down control of visual attention plays a critical role in development of skill in visual art and may also be a window into creative thinking. Copyright © 2016 Elsevier Ltd. All rights reserved.

Software Hardware Asset Reuse Enterprise (SHARE) Repository Framework: Related Work and Development Plan

DTIC Science & Technology

2009-08-19

designed to collect the data and assist the analyst in drawing relationships between the data. Palantir Technologies has created one such software...application to support the DoD intelligence community by providing robust capabilities for managing data from various sources10. The Palantir tool...www.palantirtech.com/ - 38 - Figure 17. Palantir Graphical Interface (Gordon-Schlosberg, 2008) Similar examples of the use of ontologies to support data

Regime Change and the Role of Airpower

DTIC Science & Technology

2006-08-01

cut off aid to Batista, Samoza, Marcos , and the Shah. Each dictator sub- sequently fell.”11 Like the domestic winning coalition, foreign countries and...Vice Pres. Hubert Humphrey provides a robust example of a regime change in a democracy. The previous sections detailed 34 AMERICAN REGIME CHANGE how...the Democrats and draw support away from the incumbent candidate, Vice Pres. Hubert Humphrey. Even among Johnson’s advocates and personal advisors

Metabolic network visualization eliminating node redundance and preserving metabolic pathways

PubMed Central

Bourqui, Romain; Cottret, Ludovic; Lacroix, Vincent; Auber, David; Mary, Patrick; Sagot, Marie-France; Jourdan, Fabien

2007-01-01

Background The tools that are available to draw and to manipulate the representations of metabolism are usually restricted to metabolic pathways. This limitation becomes problematic when studying processes that span several pathways. The various attempts that have been made to draw genome-scale metabolic networks are confronted with two shortcomings: 1- they do not use contextual information which leads to dense, hard to interpret drawings, 2- they impose to fit to very constrained standards, which implies, in particular, duplicating nodes making topological analysis considerably more difficult. Results We propose a method, called MetaViz, which enables to draw a genome-scale metabolic network and that also takes into account its structuration into pathways. This method consists in two steps: a clustering step which addresses the pathway overlapping problem and a drawing step which consists in drawing the clustered graph and each cluster. Conclusion The method we propose is original and addresses new drawing issues arising from the no-duplication constraint. We do not propose a single drawing but rather several alternative ways of presenting metabolism depending on the pathway on which one wishes to focus. We believe that this provides a valuable tool to explore the pathway structure of metabolism. PMID:17608928

Task-induced frequency modulation features for brain-computer interfacing.

PubMed

Jayaram, Vinay; Hohmann, Matthias; Just, Jennifer; Schölkopf, Bernhard; Grosse-Wentrup, Moritz

2017-10-01

Task-induced amplitude modulation of neural oscillations is routinely used in brain-computer interfaces (BCIs) for decoding subjects' intents, and underlies some of the most robust and common methods in the field, such as common spatial patterns and Riemannian geometry. While there has been some interest in phase-related features for classification, both techniques usually presuppose that the frequencies of neural oscillations remain stable across various tasks. We investigate here whether features based on task-induced modulation of the frequency of neural oscillations enable decoding of subjects' intents with an accuracy comparable to task-induced amplitude modulation. We compare cross-validated classification accuracies using the amplitude and frequency modulated features, as well as a joint feature space, across subjects in various paradigms and pre-processing conditions. We show results with a motor imagery task, a cognitive task, and also preliminary results in patients with amyotrophic lateral sclerosis (ALS), as well as using common spatial patterns and Laplacian filtering. The frequency features alone do not significantly out-perform traditional amplitude modulation features, and in some cases perform significantly worse. However, across both tasks and pre-processing in healthy subjects the joint space significantly out-performs either the frequency or amplitude features alone. This result only does not hold for ALS patients, for whom the dataset is of insufficient size to draw any statistically significant conclusions. Task-induced frequency modulation is robust and straight forward to compute, and increases performance when added to standard amplitude modulation features across paradigms. This allows more information to be extracted from the EEG signal cheaply and can be used throughout the field of BCIs.

Paracetamol in Older People: Towards Evidence-Based Dosing?

PubMed

Mian, Paola; Allegaert, Karel; Spriet, Isabel; Tibboel, Dick; Petrovic, Mirko

2018-06-19

Paracetamol is the most commonly used analgesic in older people, and is mainly dosed according to empirical dosing guidelines. However, the pharmacokinetics and thereby the effects of paracetamol can be influenced by physiological changes occurring with ageing. To investigate the steps needed to reach more evidence-based paracetamol dosing regimens in older people, we applied the concepts used in the paediatric study decision tree. A search was performed to retrieve studies on paracetamol pharmacokinetics and safety in older people (> 60 years) or studies that performed a (sub) analysis of pharmacokinetics and/or safety in older people. Of 6088 articles identified, 259 articles were retained after title and abstract screening. Further abstract and full-text screening identified 27 studies, of which 20 described pharmacokinetics and seven safety. These studies revealed no changes in absorption with ageing. A decreased (3.9-22.9%) volume of distribution (V d ) in robust older subjects and a further decreased V d (20.3%) in frail older compared with younger subjects was apparent. Like V d , age and frailty decreased paracetamol clearance (29-45.7 and 37.5%) compared with younger subjects. Due to limited and heterogeneous evidence, it was difficult to draw firm and meaningful conclusions on changed risk for paracetamol safety in older people. This review is a first step towards bridging knowledge gaps to move to evidence-based paracetamol dosing in older subjects. Remaining knowledge gaps are safety when using therapeutic dosages, pharmacokinetics changes in frail older people, and to what extent changes in paracetamol pharmacokinetics should lead to a change in dosage in frail and robust older people.

Perceptions of diabetes obtained through drawing in childhood and adolescence

PubMed Central

Pera, Pilar Isla; Lois, María Palacin; Matheu, Carmen López; Pérez, María Honrubia; Rodriguez, Ana María Gómez; Camps, Eulalia Armengol; Villalba, Carmen Sanchez; Soria, Roser Insa; Cuadra, Assumpta Rigol; Marre, Diana

2013-01-01

Objective To examine whether drawing is useful in the detection of problems of psychosocial adaptation in children and adolescents with type 1 diabetes (T1D) and in improving communication with health professionals. Methods We performed an exploratory descriptive study in 199 children and adolescents with T1D aged 4–13 years. The participants were asked to render a drawing on a suggested topic. The variables analyzed were related to the drawing and to clinical and sociodemographic data. Results Most participants showed evidence of having a well-balanced personality, but there were also signs of affective or psychosocial difficulties. Conclusion Drawing is a useful technique by which to identify children’s and adolescents’ feelings and possible problems in adapting to T1D, as well as to gain information directly from the children themselves. Future studies should delimit the possibilities of this technique in clinical practice in greater detail. PMID:23814467

Effects of lumbopelvic sling and abdominal drawing-in exercises on lung capacity in healthy adults.

PubMed

Kim, Myoung-Kwon; Cha, Hyun-Gyu; Shin, Young-Jun

2016-08-01

[Purpose] To examine the effects of lumbopelvic sling and abdominal drawing-in exercises on the lung capacities of healthy subjects. [Subjects and Methods] Twenty-nine healthy subjects with no orthopedic history of the back were recruited. Subjects were randomly assigned to a experimental group and control group. Subjects were allocated to one of two groups; an experimental group that underwent lumbopelvic sling and abdominal drawing-in exercises and a control group that underwent treadmill and abdominal drawing-in exercises. Lung capacities were evaluated 4 weeks after exercises. [Results] The experimental group showed significant increments in EV, ERV, IRV, VT vs. pre-intervention results, and the control group showed significant increments in the EVC and IRV. Significant intergroup differences were observed in terms of post-training gains in EVC, IRV, and VT. [Conclusion] Combined application of lumbopelvic sling and abdominal drawing-in exercises were found to have a positive effect on lung capacity.

Projective drawings for assessing stress among subjects with medical symptoms compatible with sick building syndrome, and validation of a modified version of the Stress Load Index from the Drawing Personality Profile: a pilot study.

PubMed

Runeson, Roma; Wahlstedt, Kurt; Norbäck, Dan

2007-02-01

It was hypothesized that subjects with medical symptoms would show more signs of stress in projective drawings. A Stress Load Index, including five signs of stress in drawings, was evaluated. A questionnaire with an instruction to draw "a person in the rain" was sent to a cohort of 195 subjects, and the drawings were analysed blindly for eight stress items. Men had a higher index than women (p < .05) and drew clouds more often (p < .05). Drawing of clouds was associated with headache (adjOR = 4.28; 95% CI 1.75; 11.68). Drawing of puddles was associated with ocular symptoms (adjOR = 3.22; 95% CI 1.38, 7.50), facial dermal symptoms (adjOR= 2.94; 95% CI 1.28, 6.81), and tiredness (adjOR = 2.44; 95% CI 1.05, 5.67). Drawing of long rain strokes was associated with nasal symptoms (adjOR = 2.28; 95% CI 1.05, 2.06) and headache (adjOR = 3.20; 95% CI 1.28, 8.05). Age and stress load were predictors of sick building syndrome symptoms (p < .05). In conclusion, a nonverbal projective drawing test detected sex differences which represent directions opposite to those with verbal methods. These need empirical assessment.

Applying the Uses and Gratifications Theory to Compare Higher Education Students' Motivation for Using Social Networking Sites: Experiences from Iran, Malaysia, United Kingdom, and South Africa

ERIC Educational Resources Information Center

Karimi, Leila; Khodabandelou, Rouhollah; Ehsani, Maryam; Ahmad, Muhammad

2014-01-01

Drawing from the Uses and Gratifications Theory, this study examined the Gratification Sought and the Gratification Obtained from using Social Networking Sites among Iranian, Malaysian, British, and South African higher education students. This comparison allowed to drawing conclusions about how social networking sites fulfill users' needs with…

Boy v. Girl? How Gender Shapes Who We Are, What We Want, and How We Get Along.

ERIC Educational Resources Information Center

Abrahams, George; Ahlbrand, Sheila

Noting that the middle-school years are a time when adolescents "try on" roles and attitudes, test boundaries, and draw tentative conclusions about personal and social behaviors, this book draws on findings of a survey of nearly 2,000 10- to 17-year-olds regarding perceived and real differences between girls and boys to guide teens…

Older Age Relates to Worsening of Fine Motor Skills: A Population-Based Study of Middle-Aged and Elderly Persons

PubMed Central

Hoogendam, Yoo Young; van der Lijn, Fedde; Vernooij, Meike W.; Hofman, Albert; Niessen, Wiro J.; van der Lugt, Aad; Ikram, M. Arfan; van der Geest, Jos N.

2014-01-01

Introduction: In a population-based study of 1,912 community-dwelling persons of 45 years and older, we investigated the relation between age and fine motor skills using the Archimedes spiral-drawing test. Also, we studied the effect of brain volume on fine motor skills. Methods: Participants were required to trace a template of a spiral on an electronic drawing board. Clinical scores from this test were obtained by visual assessment of the drawings. Quantitative measures were objectively determined from the recorded data of the drawings. As tremor is known to occur increasingly with advancing age, we also rated drawings to assess presence of tremor. Results: We found presence of a tremor in 1.3% of the drawings. In the group without tremor, we found that older age was related to worse fine motor skills. Additionally, participants over the age of 75 showed increasing deviations from the template when drawing the spiral. Larger cerebral volume and smaller white matter lesion volume were related to better spiral-drawing performance, whereas cerebellar volume was not related to spiral-drawing performance. Conclusion: Older age is related to worse fine motor skills, which can be captured by clinical scoring or quantitative measures of the Archimedes spiral-drawing test. Persons with a tremor performed worse on almost all measures of the spiral-drawing test. Furthermore, larger cerebral volume is related to better fine motor skills. PMID:25309436

Dry writing of highly conductive electrodes on papers by using silver nanoparticle-graphene hybrid pencils.

PubMed

Park, Jun-Ho; Park, Myung-Joo; Lee, Jang-Sik

2017-01-05

The development of paper electronics would enable realization of extremely cheap devices for portable, disposable, and environmentally-benign electronics. Here, we propose a simple dry-writing tool similar to a pencil, which can be used to draw electrically conducting lines on paper for use in paper-based electronic devices. The fabricated pencil is composed of silver nanoparticles decorated on graphene layers to construct layered hybrid nanostructures. This pencil can draw highly conductive lines that are flexible and foldable on conventional papers. Electrodes drawn using this pencil on conventional copy paper are stable during repetitive mechanical folding and highly resistant to moisture/chemicals. This pencil can draw a conductive line where its resistance can be tuned by changing the amount of nanoparticles. A nonvolatile memory device is realized on papers by hand written lines with different resistance. All memory elements are composed of carbons on papers, so complete data security can be achieved by burning the memory papers. This work will provide a new opportunity to fabricate electronic devices on real papers with good conductivity as well as robust mechanical/chemical stability.

Mexico and the 21st Century Power Partnership: Paving the Way to a Greener, Smarter, More Flexible Grid

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The 21st Century Power Partnership's program in Mexico (21CPP Mexico) is one initiative of the Clean Energy Ministerial carried out in cooperation with government and local stakeholders, drawing upon an international community of power system expertise.The overall goal of this program is to support Mexico's power system transformation by accelerating the transition to a reliable, financially robust, and low-carbon system.

VisIt: An End-User Tool for Visualizing and Analyzing Very Large Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Childs, Hank; Brugger, Eric; Whitlock, Brad

2012-11-01

VisIt is a popular open source tool for visualizing and analyzing big data. It owes its success to its foci of increasing data understanding, large data support, and providing a robust and usable product, as well as its underlying design that fits today's supercomputing landscape. This report, which draws heavily from an earlier publication at the SciDAC Conference in 2011 describes the VisIt project and its accomplishments.

Perseveration Found in a Human Drawing Task: Six-Fingered Hands Drawn by Patients with Right Anterior Insula and Operculum Damage

PubMed Central

Niki, Chiharu; Maruyama, Takashi; Muragaki, Yoshihiro; Kumada, Takatsune

2014-01-01

Background. Perseveration has been observed in a number of behavioural contexts, including speaking, writing, and drawing. However, no previous report describes patients who show perseveration only for drawing a human figure. Objective. The present report describes a group of patients who show body awareness-related cognitive impairment during a human figure drawing task, a different presentation from previously described neuropsychological cases. Methods. Participants were 15 patients who had a frontal lobe brain tumour around the insula cortex of the right hemisphere and had subsequently undergone a neurosurgical resective operation. Participants were asked to draw a human figure in both “hands-down” and “hands-up” configurations. Results. Eight of the 15 patients drew a human figure with six fingers during the “hands-up” and the “hands-down” human figure drawing tasks (one patient drew eight fingers). A statistical analysis of potential lesion areas revealed damage to the right anterior frontal insula and operculum in this group of patients relative to the five-finger drawing group. Conclusions. Our findings reveal a newly described neuropsychological phenomenon that could reflect impairment in attention directed towards body representations. PMID:24876665

Using drawings to explore patients’ perceptions of their illness: a scoping review

PubMed Central

Cheung, Melissa Mei Yin; Saini, Bandana; Smith, Lorraine

2016-01-01

Background An emerging approach for investigating patient perspectives of their illness is the use of drawings. Objective This scoping review consolidates findings from current literature regarding the use of drawings to explore patients’ perceptions and experiences of their illness and treatment. Methods Electronic databases (Medline, PubMed, Embase, PsychINFO, Cinahl, Art Index and Scopus) and reference lists were searched to identify published English language studies using participant-generated drawings to explore adults’ perceptions and experiences of their illness and treatment. Using the scoping methodological framework, data were analyzed with respect to each study’s design, key findings and implications. Results Thirty-two studies were identified and these reflected diversities in both health conditions and methods of data collection and analysis. Participants’ drawings revealed new, insightful knowledge about patients’ perceptions, beliefs and experiences of their condition and were associated with clinical and psychological markers of health. Drawing was a powerful adjunct to traditional data collection approaches, and demonstrated potential benefits for participants. This review provides detailed insights and guidance on the use of drawings in research and clinical practice. Conclusion Drawing is a novel and potentially valuable technique for exploring patients’ perceptions and experiences about their illness and treatment. Advancing the methodology and applicability of drawings in this area will assist in the future development of this technique, with benefits for the patient, researcher and health care professional alike. PMID:27920550

Selection of species and sampling areas: The importance of inference

Treesearch

Paul Stephen Corn

2009-01-01

Inductive inference, the process of drawing general conclusions from specific observations, is fundamental to the scientific method. Platt (1964) termed conclusions obtained through rigorous application of the scientific method as "strong inference" and noted the following basic steps: generating alternative hypotheses; devising experiments, the...

Robust rankings of socioeconomic health inequality using a categorical variable.

PubMed

Makdissi, Paul; Yazbeck, Myra

2017-09-01

When assessing socioeconomic health inequalities, researchers often draw upon measures of income inequality that were developed for ratio scale variables. As a result, the use of categorical data (such as self-reported health status) produces rankings that may be arbitrary and contingent to the numerical scale adopted. In this paper, we develop a method that overcomes this issue by providing conditions for which these rankings are invariant to the numerical scale chosen by the researcher. In doing so, we draw on the insight provided by Allison and Foster (2004) and extend their method to the dimension of socioeconomic inequality by exploiting the properties of rank-dependent indices such as Wagstaff (2002) achievement and extended concentration indices. We also provide an empirical illustration using the National Institute of Health Survey 2012. Copyright © 2017 John Wiley & Sons, Ltd.

Rehabilitation or compensation: time for a fresh perspective on speech and language therapy for dysphagia and Parkinson's disease?

PubMed

Smith, Sarah K; Roddam, Hazel; Sheldrick, Heulwen

2012-01-01

Dysphagia is a common symptom of Parkinson's disease and can have negative consequences for physical health and quality of life. A variety of treatment options are available to clinicians working with people who have dysphagia and Parkinson's disease. These options can be broadly categorized as being compensatory or rehabilitative in nature. To explore the evidence behind treatment options available to clinicians working with dysphagia and Parkinson's disease and to draw conclusions about whether compensatory or rehabilitative approaches are likely to provide the best outcomes for our patients. A critical literature review of compensatory and rehabilitative interventions for dysphagia in Parkinson's disease was undertaken. Relevant studies were analysed for their robustness and potential clinical applications. General conclusions were drawn based on the evidence base identified in this review. This review outlines the lack of evidence supporting both compensatory and rehabilitative methods of treating dysphagia in Parkinson's disease. It directs clinicians and researchers towards areas that require further investigation. To date, compensatory methods of treating dysphagia in Parkinson's disease have received more research attention than rehabilitative methods and yet neither approach has a strong evidence base. This review argues that rehabilitative methods could possibly have greater potential to increase swallowing safety and improve quality of life in the long-term than compensatory methods alone. However, at present there is a lack of research in this area. © 2012 Royal College of Speech and Language Therapists.

Financial Incentives to Promote Active Travel

PubMed Central

Martin, Adam; Suhrcke, Marc; Ogilvie, David

2012-01-01

Context Financial incentives, including taxes and subsidies, can be used to encourage behavior change. They are common in transport policy for tackling externalities associated with use of motor vehicles, and in public health for influencing alcohol consumption and smoking behaviors. Financial incentives also offer policymakers a compromise between “nudging,” which may be insufficient for changing habitual behavior, and regulations that restrict individual choice. Evidence acquisition The literature review identified studies published between January 1997 and January 2012 of financial incentives relating to any mode of travel in which the impact on active travel, physical activity, or obesity levels was reported. It encompassed macroenvironmental schemes, such as gasoline taxes, and microenvironmental schemes, such as employer-subsidized bicycles. Five relevant reviews and 20 primary studies (of which nine were not included in the reviews) were identified. Evidence synthesis The results show that more-robust evidence is required if policymakers are to maximize the health impact of fiscal policy relating to transport schemes of this kind. Conclusions Drawing on a literature review and insights from the SLOTH (sleep, leisure, occupation, transportation, and home-based activities) time-budget model, this paper argues that financial incentives may have a larger role in promoting walking and cycling than is acknowledged generally. PMID:23159264

Effectiveness of propolis on oral health: a meta-analysis.

PubMed

Hwu, Yueh-Juen; Lin, Feng-Yu

2014-12-01

The use of propolis mouth rinse or gel as a supplementary intervention has increased during the last decade in Taiwan. However, the effect of propolis on oral health is not well understood. The purpose of this meta-analysis was to present the best available evidence regarding the effects of propolis use on oral health, including oral infection, dental plaque, and stomatitis. Researchers searched seven electronic databases for relevant articles published between 1969 and 2012. Data were collected using inclusion and exclusion criteria. The Joanna Briggs Institute Meta Analysis of Statistics Assessment and Review Instrument was used to evaluate the quality of the identified articles. Eight trials published from 1997 to 2011 with 194 participants had extractable data. The result of the meta-analysis indicated that, although propolis had an effect on reducing dental plaque, this effect was not statistically significant. The results were not statistically significant for oral infection or stomatitis. Although there are a number of promising indications, in view of the limited number and quality of studies and the variation in results among studies, this review highlights the need for additional well-designed trials to draw conclusions that are more robust.

Genetics of wellbeing and its components satisfaction with life, happiness, and quality of life: a review and meta-analysis of heritability studies.

PubMed

Bartels, Meike

2015-03-01

Wellbeing is a major topic of research across several disciplines, reflecting the increasing recognition of its strong value across major domains in life. Previous twin-family studies have revealed that individual differences in wellbeing are accounted for by both genetic as well as environmental factors. A systematic literature search identified 30 twin-family studies on wellbeing or a related measure such as satisfaction with life or happiness. Review of these studies showed considerable variation in heritability estimates (ranging from 0 to 64 %), which makes it difficult to draw firm conclusions regarding the genetic influences on wellbeing. For overall wellbeing twelve heritability estimates, from 10 independent studies, were meta-analyzed by computing a sample size weighted average heritability. Ten heritability estimates, derived from 9 independent samples, were used for the meta-analysis of satisfaction with life. The weighted average heritability of wellbeing, based on a sample size of 55,974 individuals, was 36 % (34-38), while the weighted average heritability for satisfaction with life was 32 % (29-35) (n = 47,750). With this result a more robust estimate of the relative influence of genetic effects on wellbeing is provided.

The Statistical Mechanics of Ideal MHD Turbulence

NASA Technical Reports Server (NTRS)

Shebalin, John V.

2003-01-01

Turbulence is a universal, nonlinear phenomenon found in all energetic fluid and plasma motion. In particular. understanding magneto hydrodynamic (MHD) turbulence and incorporating its effects in the computation and prediction of the flow of ionized gases in space, for example, are great challenges that must be met if such computations and predictions are to be meaningful. Although a general solution to the "problem of turbulence" does not exist in closed form, numerical integrations allow us to explore the phase space of solutions for both ideal and dissipative flows. For homogeneous, incompressible turbulence, Fourier methods are appropriate, and phase space is defined by the Fourier coefficients of the physical fields. In the case of ideal MHD flows, a fairly robust statistical mechanics has been developed, in which the symmetry and ergodic properties of phase space is understood. A discussion of these properties will illuminate our principal discovery: Coherent structure and randomness co-exist in ideal MHD turbulence. For dissipative flows, as opposed to ideal flows, progress beyond the dimensional analysis of Kolmogorov has been difficult. Here, some possible future directions that draw on the ideal results will also be discussed. Our conclusion will be that while ideal turbulence is now well understood, real turbulence still presents great challenges.

Weight of evidence approaches for the identification of endocrine disrupting properties of chemicals: Review and recommendations for EU regulatory application.

PubMed

Gross, Melanie; Green, Richard M; Weltje, Lennart; Wheeler, James R

2017-12-01

A Weight-of-evidence (WoE) evaluation should be applied in assessing all the available data for the identification of endocrine disrupting (ED) properties of chemicals. The European Commission draft acts specifying criteria under the biocidal products and plant protection products regulations require that WoE is implemented for the assessment of such products. However, only some general considerations and principles of how a WoE should be conducted are provided. This paper reviews WoE approaches to distil key recommendations specifically for the evaluation of potential ED properties of chemicals. In a manner, which is consistent with existing, published WoE frameworks, the WoE evaluation of ED properties can be divided into four phases: 1) Definition of causal questions and data gathering and selection, 2) Review of individual studies, 3) Data integration and evaluation, and 4) Drawing conclusions based on inferences. Recommendations are made on how to conduct each phase robustly and transparently to help guide the WoE evaluation of potential endocrine disrupting properties of chemicals within a European regulatory context. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Radiotherapy of meningioma: a treatment in need of radiobiological research.

PubMed

Pinzi, Valentina; Bisogno, Ilaria; Prada, Francesco; Ciusani, Emilio; Fariselli, Laura

2018-05-18

Meningiomas account for one third of primary intracranial tumors, nevertheless information on meningioma cell lines and in vivo models is scant. Although radiotherapy is one of the most relevant therapeutic options for the treatment patients with meningioma, radiobiological research to understand tumor responses to this treatment is far from being thoroughly understood. The aim of this report is to provide a comprehensive picture of the current literature on this field, so as to foster s research in this regard. We carried out a review of meningioma radiobiology based on a peer-reviewed PubMed search. As a result of our study, we can confirm that the main limitation of radiobiological research into meningioma is the paucity of robust in vitro and in vivo models. Alternative approaches to overcome the already identified problems, and to allow better understanding of the entire histopathological spectrum of meningiomas have been explored. A radiobiological perspective of meningioma may help to improve clinical results both in terms of tumour control and healthy tissue sparing. Although we are far from drawing any conclusions, this review can lead researchers to identify some cues for future areas of study.

Traditional and new composite endpoints in heart failure clinical trials: facilitating comprehensive efficacy assessments and improving trial efficiency.

PubMed

Anker, Stefan D; Schroeder, Stefan; Atar, Dan; Bax, Jeroen J; Ceconi, Claudio; Cowie, Martin R; Crisp, Adam; Dominjon, Fabienne; Ford, Ian; Ghofrani, Hossein-Ardeschir; Gropper, Savion; Hindricks, Gerhard; Hlatky, Mark A; Holcomb, Richard; Honarpour, Narimon; Jukema, J Wouter; Kim, Albert M; Kunz, Michael; Lefkowitz, Martin; Le Floch, Chantal; Landmesser, Ulf; McDonagh, Theresa A; McMurray, John J; Merkely, Bela; Packer, Milton; Prasad, Krishna; Revkin, James; Rosano, Giuseppe M C; Somaratne, Ransi; Stough, Wendy Gattis; Voors, Adriaan A; Ruschitzka, Frank

2016-05-01

Composite endpoints are commonly used as the primary measure of efficacy in heart failure clinical trials to assess the overall treatment effect and to increase the efficiency of trials. Clinical trials still must enrol large numbers of patients to accrue a sufficient number of outcome events and have adequate power to draw conclusions about the efficacy and safety of new treatments for heart failure. Additionally, the societal and health system perspectives on heart failure have raised interest in ascertaining the effects of therapy on outcomes such as repeat hospitalization and the patient's burden of disease. Thus, novel methods for using composite endpoints in clinical trials (e.g. clinical status composite endpoints, recurrent event analyses) are being applied in current and planned trials. Endpoints that measure functional status or reflect the patient experience are important but used cautiously because heart failure treatments may improve function yet have adverse effects on mortality. This paper discusses the use of traditional and new composite endpoints, identifies qualities of robust composites, and outlines opportunities for future research. © 2016 The Authors. European Journal of Heart Failure © 2016 European Society of Cardiology.

Social control and coercion in addiction treatment: towards evidence-based policy and practice.

PubMed

Wild, T Cameron

2006-01-01

Social pressures are often an integral part of the process of seeking addiction treatment. However, scientists have not developed conclusive evidence on the processes, benefits and limitations of using legal, formal and informal social control tactics to inform policy makers, service providers and the public. This paper characterizes barriers to a robust interdisciplinary analysis of social control and coercion in addiction treatment and provides directions for future research. Conceptual analysis and review of key studies and trends in the area are used to describe eight implicit assumptions underlying policy, practice and scholarship on this topic. Many policies, programmes and researchers are guided by a simplistic behaviourist and health-service perspective on social controls that (a) overemphasizes the use of criminal justice systems to compel individuals into treatment and (b) fails to take into account provider, patient and public views. Policies and programmes that expand addiction treatment options deserve support. However, drawing a firm distinction between social controls (objective use of social pressure) and coercion (client perceptions and decision-making processes) supports a parallel position that rejects treatment policies, programmes, and associated practices that create client perceptions of coercion.

Sleep duration and all-cause mortality: a critical review of measurement and associations

PubMed Central

Kurina, Lianne M.; McClintock, Martha K.; Chen, Jen-Hao; Waite, Linda J.; Thisted, Ronald A.; Lauderdale, Diane S.

2013-01-01

Purpose Variation in sleep duration has been linked with mortality risk. The purpose of this review is to provide an updated evaluation of the literature on sleep duration and mortality, including a critical examination of sleep duration measurement and an examination of correlates of self-reported sleep duration. Methods We did a systematic search of studies reporting associations between sleep duration and all-cause mortality and extracted the sleep duration measure and the measure(s) of association. Results We identified 42 prospective studies of sleep duration and mortality drawing on 35 distinct study populations across the globe. Unlike previous reviews, we find that the published literature does not support a consistent finding of an association between self-reported sleep duration and mortality. Most studies have employed survey measures of sleep duration, which are not highly correlated with estimates based on physiologic measures. Conclusions Despite a large body of literature, it is premature to conclude, as previous reviews have, that a robust, U-shaped association between sleep duration and mortality risk exists across populations. Careful attention must be paid to measurement, response bias, confounding, and reverse causation in the interpretation of associations between sleep duration and mortality. PMID:23622956

Drawing conclusions: a re-examination of empirical and conceptual bases for psychological evaluation of children from their drawings.

PubMed

Thomas, G V; Jolley, R P

1998-05-01

Although consideration of children's art work (usually drawings) in clinical investigations of children referred to psychologists is fairly common, there is little evidence for the reliability and validity of such assessments. We consider a variety of possible mechanisms which could operate to influence the characteristics of children's drawings, and review the evidence that such mechanisms operate to allow meaningful psychological evaluations of children from their drawings. The problem for making a reliable interpretation of the significance of a drawing is that a given feature could plausibly support several very different interpretations, depending which of many possible processes was active or dominant in the production of the drawing. Evidence from studies of clinical populations and experimental studies with non-selected samples are reviewed in the light of these possibilities. The review indicates that drawings are inaccurate and unreliable as personality or state assessments but can be influenced by children's emotional attitudes towards the topics depicted. The form of that expression, however, may be personal and idiosyncratic. Analogue studies of these effects undertaken with non-clinical samples under controlled conditions have produced mixed results. At best the reported effects are small. Children's drawings on their own are too complexly determined and inherently ambiguous to be reliable sole indicators of the emotional experiences of the children who drew them. Further research is needed to establish the extent to which such drawings can usefully facilitate assessment of children by other means or provide useful support as one of several converging lines of evidence.

Task-induced frequency modulation features for brain-computer interfacing

NASA Astrophysics Data System (ADS)

Jayaram, Vinay; Hohmann, Matthias; Just, Jennifer; Schölkopf, Bernhard; Grosse-Wentrup, Moritz

2017-10-01

Objective. Task-induced amplitude modulation of neural oscillations is routinely used in brain-computer interfaces (BCIs) for decoding subjects’ intents, and underlies some of the most robust and common methods in the field, such as common spatial patterns and Riemannian geometry. While there has been some interest in phase-related features for classification, both techniques usually presuppose that the frequencies of neural oscillations remain stable across various tasks. We investigate here whether features based on task-induced modulation of the frequency of neural oscillations enable decoding of subjects’ intents with an accuracy comparable to task-induced amplitude modulation. Approach. We compare cross-validated classification accuracies using the amplitude and frequency modulated features, as well as a joint feature space, across subjects in various paradigms and pre-processing conditions. We show results with a motor imagery task, a cognitive task, and also preliminary results in patients with amyotrophic lateral sclerosis (ALS), as well as using common spatial patterns and Laplacian filtering. Main results. The frequency features alone do not significantly out-perform traditional amplitude modulation features, and in some cases perform significantly worse. However, across both tasks and pre-processing in healthy subjects the joint space significantly out-performs either the frequency or amplitude features alone. This result only does not hold for ALS patients, for whom the dataset is of insufficient size to draw any statistically significant conclusions. Significance. Task-induced frequency modulation is robust and straight forward to compute, and increases performance when added to standard amplitude modulation features across paradigms. This allows more information to be extracted from the EEG signal cheaply and can be used throughout the field of BCIs.

Comparison of changes in oxygenated hemoglobin during the tree-drawing task between patients with schizophrenia and healthy controls

PubMed Central

Nakano, Shinya; Shoji, Yoshihisa; Morita, Kiichiro; Igimi, Hiroyasu; Sato, Mamoru; Ishii, Youhei; Kondo, Akihiko; Uchimura, Naohisa

2018-01-01

Background Tree-drawing test is used as a projective psychological test that expresses the abnormal internal experience in patients with schizophrenia (SZ). Despite the widely accepted view that the cognitive function is involved in characteristic tree-drawing in patients with SZ, no study has psychophysiologically examined it. The present study aimed to investigate the involvement of cognitive function during tree-drawing in patients with SZ. For that purpose, we evaluated the brain function in patients with SZ during a tree-drawing task by using near-infrared spectroscopy (NIRS) and compared them with those in healthy controls. Patients and methods The subjects were 28 healthy controls and 28 patients with SZ. Changes in the oxygenated hemoglobin ([oxy-Hb]) concentration in both the groups during the task of drawing a tree imagined freely (free-drawing task) and the task of copying an illustration of a tree (copying task) were measured by using NIRS. Results Because of the difference between the task conditions, [oxy-Hb] levels in controls during the free-drawing task were higher than that during the copying task at the bilateral frontal pole regions and left inferior frontal region. Because of the difference between the groups, [oxy-Hb] levels at the left middle frontal region, bilateral inferior frontal regions, bilateral inferior parietal regions, and left superior temporal region during the free-drawing task in patients were lower than that in controls. Conclusion [oxy-Hb] during the tree-drawing task in patients with SZ was lower than that in healthy controls. Our results suggest that brain dysfunction in patients with SZ might be associated with their tree-drawing. PMID:29719398

Drawing conclusions from within-group comparisons and selected subsets of data leads to unsubstantiated conclusions: Letter regarding Malakellis et al.

USDA-ARS?s Scientific Manuscript database

Malakellis et al. conducted an ambitious quasi-experimental evaluation of "multiple initiatives at [the] individual, community, and school policy level to support healthier nutrition and physical activity" among children. In the abstract they concluded, "There was some evidence of effectiveness of t...

Identification of inelastic parameters based on deep drawing forming operations using a global-local hybrid Particle Swarm approach

NASA Astrophysics Data System (ADS)

Vaz, Miguel; Luersen, Marco A.; Muñoz-Rojas, Pablo A.; Trentin, Robson G.

2016-04-01

Application of optimization techniques to the identification of inelastic material parameters has substantially increased in recent years. The complex stress-strain paths and high nonlinearity, typical of this class of problems, require the development of robust and efficient techniques for inverse problems able to account for an irregular topography of the fitness surface. Within this framework, this work investigates the application of the gradient-based Sequential Quadratic Programming method, of the Nelder-Mead downhill simplex algorithm, of Particle Swarm Optimization (PSO), and of a global-local PSO-Nelder-Mead hybrid scheme to the identification of inelastic parameters based on a deep drawing operation. The hybrid technique has shown to be the best strategy by combining the good PSO performance to approach the global minimum basin of attraction with the efficiency demonstrated by the Nelder-Mead algorithm to obtain the minimum itself.

10 rules for managing global innovation.

PubMed

Wilson, Keeley; Doz, Yves L

2012-10-01

More and more companies recognize that their dispersed, global operations are a treasure trove of ideas and capabilities for innovation. But it's proving harder than expected to unearth those ideas or exploit those capabilities. Part of the problem is that companies manage global innovation the same way they manage traditional, single-location projects. Single-location projects draw on a large reservoir of tacit knowledge, shared context, and trust that global projects lack. The management challenge, therefore, is to replicate the positive aspects of colocation while harnessing the opportunities of dispersion. In this article, Insead's Wilson and Doz draw on research into global strategy and innovation to present a set of guidelines for setting up and managing global innovation. They explore in detail the challenges that make global projects inherently different and show how these can be overcome by applying superior project management skills across teams, fostering a strong collaborative culture, and using a robust array of communications tools.

Clinical supervision in the 21st century: revisiting pressing needs and impressing possibilities.

PubMed

Watkins, C Edward

2014-01-01

What are some of the most pressing needs currently confronting clinical supervision? In this paper, I give attention to that question. Drawing on two 1990 reviews for comparative purposes, I examine where supervision is now relative to four areas: (a) supervision training and practice; (b) measurement; (c) difference and diversity; and (d) research. Lines of advance, pressing needs, and potential remedies are considered across each area. Effort is made to accentuate the "robustly international" nature of clinical supervision and its increasing globalization.

Fracture - An Unforgiving Failure Mode

NASA Technical Reports Server (NTRS)

Goodin, James Ronald

2006-01-01

During the 2005 Conference for the Advancement for Space Safety, after a typical presentation of safety tools, a Russian in the audience simply asked, "How does that affect the hardware?" Having participated in several International System Safety Conferences, I recalled that most attention is dedicated to safety tools and little, if any, to hardware. The intent of this paper on the hazard of fracture and failure modes associated with fracture is my attempt to draw attention to the grass roots of system safety - improving hardware robustness and resilience.

Comparison of changes in the mobility of the pelvic floor muscle on during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction

PubMed Central

Jung, Halim; Jung, Sangwoo; Joo, Sunghee; Song, Changho

2016-01-01

[Purpose] The purpose of this study was to compare changes in the mobility of the pelvic floor muscle during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. [Subjects] Thirty healthy adults participated in this study (15 men and 15 women). [Methods] All participants performed a bridge exercise and abdominal curl-up during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. Pelvic floor mobility was evaluated as the distance from the bladder base using ultrasound. [Results] According to exercise method, bridge exercise and abdominal curl-ups led to significantly different pelvic floor mobility. The pelvic floor muscle was elevated during the abdominal drawing-in maneuver and descended during maximal expiration. Finally, pelvic floor muscle mobility was greater during abdominal curl-up than during the bridge exercise. [Conclusion] According to these results, the abdominal drawing-in maneuver induced pelvic floor muscle contraction, and pelvic floor muscle contraction was greater during the abdominal curl-up than during the bridge exercise. PMID:27065532

Comparison of changes in the mobility of the pelvic floor muscle on during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction.

PubMed

Jung, Halim; Jung, Sangwoo; Joo, Sunghee; Song, Changho

2016-01-01

[Purpose] The purpose of this study was to compare changes in the mobility of the pelvic floor muscle during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. [Subjects] Thirty healthy adults participated in this study (15 men and 15 women). [Methods] All participants performed a bridge exercise and abdominal curl-up during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. Pelvic floor mobility was evaluated as the distance from the bladder base using ultrasound. [Results] According to exercise method, bridge exercise and abdominal curl-ups led to significantly different pelvic floor mobility. The pelvic floor muscle was elevated during the abdominal drawing-in maneuver and descended during maximal expiration. Finally, pelvic floor muscle mobility was greater during abdominal curl-up than during the bridge exercise. [Conclusion] According to these results, the abdominal drawing-in maneuver induced pelvic floor muscle contraction, and pelvic floor muscle contraction was greater during the abdominal curl-up than during the bridge exercise.

Non-robust numerical simulations of analogue extension experiments

NASA Astrophysics Data System (ADS)

Naliboff, John; Buiter, Susanne

2016-04-01

Numerical and analogue models of lithospheric deformation provide significant insight into the tectonic processes that lead to specific structural and geophysical observations. As these two types of models contain distinct assumptions and tradeoffs, investigations drawing conclusions from both can reveal robust links between first-order processes and observations. Recent studies have focused on detailed comparisons between numerical and analogue experiments in both compressional and extensional tectonics, sometimes involving multiple lithospheric deformation codes and analogue setups. While such comparisons often show good agreement on first-order deformation styles, results frequently diverge on second-order structures, such as shear zone dip angles or spacing, and in certain cases even on first-order structures. Here, we present finite-element experiments that are designed to directly reproduce analogue "sandbox" extension experiments at the cm-scale. We use material properties and boundary conditions that are directly taken from analogue experiments and use a Drucker-Prager failure model to simulate shear zone formation in sand. We find that our numerical experiments are highly sensitive to numerous numerical parameters. For example, changes to the numerical resolution, velocity convergence parameters and elemental viscosity averaging commonly produce significant changes in first- and second-order structures accommodating deformation. The sensitivity of the numerical simulations to small parameter changes likely reflects a number of factors, including, but not limited to, high angles of internal friction assigned to sand, complex, unknown interactions between the brittle sand (used as an upper crust equivalent) and viscous silicone (lower crust), highly non-linear strain weakening processes and poor constraints on the cohesion of sand. Our numerical-analogue comparison is hampered by (a) an incomplete knowledge of the fine details of sand failure and sand properties, and (b) likely limitations to the use of a continuum Drucker-Prager model for representing shear zone formation in sand. In some cases our numerical experiments provide reasonable fits to first-order structures observed in the analogue experiments, but the numerical sensitivity to small parameter variations leads us to conclude that the numerical experiments are not robust.

Multivariate singular spectrum analysis and the road to phase synchronization

NASA Astrophysics Data System (ADS)

Groth, Andreas; Ghil, Michael

2010-05-01

Singular spectrum analysis (SSA) and multivariate SSA (M-SSA) are based on the classical work of Kosambi (1943), Loeve (1945) and Karhunen (1946) and are closely related to principal component analysis. They have been introduced into information theory by Bertero, Pike and co-workers (1982, 1984) and into dynamical systems analysis by Broomhead and King (1986a,b). Ghil, Vautard and associates have applied SSA and M-SSA to the temporal and spatio-temporal analysis of short and noisy time series in climate dynamics and other fields in the geosciences since the late 1980s. M-SSA provides insight into the unknown or partially known dynamics of the underlying system by decomposing the delay-coordinate phase space of a given multivariate time series into a set of data-adaptive orthonormal components. These components can be classified essentially into trends, oscillatory patterns and noise, and allow one to reconstruct a robust "skeleton" of the dynamical system's structure. For an overview we refer to Ghil et al. (Rev. Geophys., 2002). In this talk, we present M-SSA in the context of synchronization analysis and illustrate its ability to unveil information about the mechanisms behind the adjustment of rhythms in coupled dynamical systems. The focus of the talk is on the special case of phase synchronization between coupled chaotic oscillators (Rosenblum et al., PRL, 1996). Several ways of measuring phase synchronization are in use, and the robust definition of a reasonable phase for each oscillator is critical in each of them. We illustrate here the advantages of M-SSA in the automatic identification of oscillatory modes and in drawing conclusions about the transition to phase synchronization. Without using any a priori definition of a suitable phase, we show that M-SSA is able to detect phase synchronization in a chain of coupled chaotic oscillators (Osipov et al., PRE, 1996). Recently, Muller et al. (PRE, 2005) and Allefeld et al. (Intl. J. Bif. Chaos, 2007) have demonstrated the usefulness of principal component analysis in detecting phase synchronization from multivariate time series. The present talk provides a generalization of this idea and presents a robust implementation thereof via M-SSA.

Methotrexate and Pregnancy

MedlinePlus

... methotrexate to draw firm conclusions. One 2009 review paper reported no increase in miscarriage or birth defect ... methotrexate in the first trimester. While reassuring, this paper does not mean there is no risk for ...

A natural driven membrane process for brackish and wastewater treatment: photovoltaic powered ED and FO hybrid system.

PubMed

Zhang, Yang; Pinoy, Luc; Meesschaert, Boudewijn; Van der Bruggen, Bart

2013-09-17

In isolated locations, remote areas, or islands, potable water is precious because of the lack of drinking water treatment facilities and energy supply. Thus, a robust and reliable water treatment system based on natural energy is needed to reuse wastewater or to desalinate groundwater/seawater for provision of drinking water. In this work, a hybrid membrane system combining electrodialysis (ED) and forward osmosis (FO), driven by renewable energy (solar energy), denoted as EDFORD (ED-FO Renewable energy Desalination), is proposed to produce high-quality water (potable) from secondary wastewater effluent or brackish water. In this hybrid membrane system, feedwater (secondary wastewater effluent or synthetic brackish water) was drawn to the FO draw solution while the organic and inorganic substances (ions, compounds, colloids and particles) were rejected. The diluted draw solution was then pumped to the solar energy driven ED. In the ED unit, the diluted draw solution was desalted and high-quality water was produced; the concentrate was recycled to the FO unit and reused as the draw solution. Results show that the water produced from this system contains a low concentration of total organic carbon (TOC), carbonate, and cations derived from the feedwater; had a low conductivity; and meets potable water standards. The water production cost considering the investment for membranes and solar panel is 3.32 to 4.92 EUR m(-3) (for 300 days of production per year) for a small size potable water production system.

Expression of pain and distress in children during dental extractions through drawings as a projective measure: A clinical study

PubMed Central

Pala, Sai Priya; Nuvvula, Sivakumar; Kamatham, Rekhalakshmi

2016-01-01

AIM: To evaluate the efficacy of drawings as a projective measure of pain and distress in children undergoing dental extractions. METHODS: Children in the age range of 4-13 years with existence of untreatable caries or over-retained primary teeth, indicated for extractions were included. Pain was assessed using one behavioral [faces, legs, activity, cry and consolability (FLACC)] scale; and a self report measure; faces pain scale-revised (FPS-R), at two points of time, after completion of local anesthetic administration and after extraction. The general behavior of children was assessed with Wright’s modification of Frankl rating scale. At the end of the session, children were instructed to represent, themselves along with the dentist and their experiences of the dental treatment through drawing. The drawings were scored utilizing Child drawing: Hospital scale (CD: H) manual and correlated with FLACC, FPS-R and Frankl using Pearson correlation test. RESULTS: A positive correlation, though statistically not significant, was observed between CD: H scores and all other considered parameters (Frankl, FPS-R and FLACC) in the present study. CONCLUSION: Drawings could not act as surrogate measure of child’s pain; however, they acted as a narrative of his/her experiences and reflection of inner emotions. Hence, drawings can be used as an additional dental armamentarium. PMID:26862509

Forum Response: Ethics in Business and Teaching.

ERIC Educational Resources Information Center

Anderson, James A.

2003-01-01

Discusses the teaching of business ethics. Draws conclusions about teaching business ethics noting that such instruction must start with the principles of capitalism and the functions of a market economy. (SG)

Surgical management of oligometastatic non-small cell lung cancer.

PubMed

Novoa, Nuria M; Varela, Gonzalo; Jiménez, Marcelo F

2016-11-01

The oligometastatic stage IV non-small cell lung cancer (NSCLC) offers a new surgical opportunity. New reported data is showing that surgery can offer a reasonable benefit, in terms of long-term survival, to some patients. The advantages of surgical treatment rely on a more adequate patient selection and a better understanding of the biology of these tumors. Currently, mediastinal involvement of the primary tumor can be identified as the most important prognostic variable after curative-intent of synchronous or metachronous metastasis. It seems clear that the routine use of combined FDG-PET and CT will help to detect the more favorable cohort of oligometastatic patients. As expected, pathological T staging of the primary tumor and the completeness of its resection are also crucial factors influencing final results. The real benefit of the local treatment over synchronous or metachronous metastasis is controversial with series showing better outcomes for metachronous lesions than for synchronous and others offering equal results. Also non conclusive results appear when analyzing different sites of metastasis. Retrospective series tend to show different outcomes depending on the affected organ while usually no differences are found in prospective ones. Most of the current evidence is based on retrospective studies on patients collected along extended periods of time. That represents a great limitation to the knowledge on this topic. Some prospective analyses have added some insight, but still the quality of the evidence is too low to allow drawing robust conclusions. As frequently concluded, prospective well designed investigation is requested to ascertain the value of surgery in this specific population of patients with extended NSCLC.

A Systematic Review of Economic Evaluations of Treatments for Borderline Personality Disorder

PubMed Central

Brettschneider, Christian; Riedel-Heller, Steffi; König, Hans-Helmut

2014-01-01

Purpose The borderline personality disorder is a common mental disorder. It is frequently associated with various mental co-morbidities and a fundamental loss of functioning. The borderline personality disorder causes high costs to society. The aim of this study was to perform a systematic literature review of existing economic evaluations of treatments for borderline personality disorder. Materials and Methods We performed a systematic literature search in MEDLINE, EMBASE, PsycINFO and NHSEED for partial and full economic evaluations regarding borderline personality disorder. Reported cost data were inflated to the year 2012 and converted into US-$ using purchasing power parities to allow for comparability. Quality assessment of the studies was performed by means of the Consensus on Health Economic Criteria checklist, a checklist developed by a Delphi method in cooperation with 23 international experts. Results We identified 6 partial and 9 full economic evaluations. The methodical quality was moderate (fulfilled quality criteria: 79.2% [SD: 15.4%] in partial economic evaluations, 77.3% [SD: 8.5%] in full economic evaluations). Most evaluations analysed psychotherapeutic interventions. Although ambiguous, most evidence exists on dialectical-behavioural therapy. Cognitive behavioural therapy and schema-focused therapy are cost-saving. Evidence on other interventions is scarce. Conclusion The economic evidence is not sufficient to draw robust conclusions for all treatments. It is possible that some treatments are cost-effective. Most evidence exists on dialectical-behavioural therapy. Yet, it is ambiguous. Further research concerning the cost-effectiveness of treatments is necessary as well as the identification of relevant cost categories and the validation of effect measures. PMID:25265185

Clinical usefulness of the clock drawing test applying rasch analysis in predicting of cognitive impairment.

PubMed

Yoo, Doo Han; Lee, Jae Shin

2016-07-01

[Purpose] This study examined the clinical usefulness of the clock drawing test applying Rasch analysis for predicting the level of cognitive impairment. [Subjects and Methods] A total of 187 stroke patients with cognitive impairment were enrolled in this study. The 187 patients were evaluated by the clock drawing test developed through Rasch analysis along with the mini-mental state examination of cognitive evaluation tool. An analysis of the variance was performed to examine the significance of the mini-mental state examination and the clock drawing test according to the general characteristics of the subjects. Receiver operating characteristic analysis was performed to determine the cutoff point for cognitive impairment and to calculate the sensitivity and specificity values. [Results] The results of comparison of the clock drawing test with the mini-mental state showed significant differences in according to gender, age, education, and affected side. A total CDT of 10.5, which was selected as the cutoff point to identify cognitive impairement, showed a sensitivity, specificity, Youden index, positive predictive, and negative predicive values of 86.4%, 91.5%, 0.8, 95%, and 88.2%. [Conclusion] The clock drawing test is believed to be useful in assessments and interventions based on its excellent ability to identify cognitive disorders.

Self-Image Perception of 171 Children and Adolescents With Cleft Lip and Palate From 22 Countries

PubMed Central

Abd-Elsayed, Alaa A.; Delgado, Sergio V.; Livingstone, Morgan

2013-01-01

Background Cleft lip (CL) and cleft palate (CP) are among the most common congenital deformities of the head and neck. They are associated with many problems, physical and psychological. We describe 171 children and adolescents with CL/CP from 22 countries who were asked to draw their faces in a self-image perception drawing 2 hours before surgery to repair their deformities. Methods The aim of the study was to explore whether children and adolescents with CL and CP perceived themselves as deformed when given the opportunity to draw their faces before surgery to repair their deformities. Children were asked to lie down on a large piece of paper to have their body outline traced. Subsequently, the children were asked to draw their faces within the outline. Results All of the children included in this study drew their faces with normal mouths. Conclusion None of the 171 patients with CL/CP drew their deformity when asked to draw their faces; the reasons are not clear. The children may have wanted to compensate for their disability with the constructive use of fantasy as they anticipated the surgery to repair their CL/CP. An additional hypothesis is that the children felt the need to draw an image that they knew represented their parents' desires. PMID:23789006

Workshop on Fielded Applications of Machine Learning

DTIC Science & Technology

1994-05-11

This report summaries the talks presented at the Workshop on Fielded Applications of Machine Learning , and draws some initial conclusions about the state of machine learning and its potential for solving real-world problems.

School Age Populations Research Needs - NCS Dietary Assessment Literature Review

Cancer.gov

Drawing conclusions about the validity of available dietary assessment instruments in school age children is hampered by the differences in instruments, research design, reference methods, and populations in the validation literature.

A systematic review and meta-analysis of online versus alternative methods for training licensed health care professionals to deliver clinical interventions.

PubMed

Richmond, Helen; Copsey, Bethan; Hall, Amanda M; Davies, David; Lamb, Sarah E

2017-11-23

Online training is growing in popularity and yet its effectiveness for training licensed health professionals (HCPs) in clinical interventions is not clear. We aimed to systematically review the literature on the effectiveness of online versus alternative training methods in clinical interventions for licensed Health Care Professionals (HCPs) on outcomes of knowledge acquisition, practical skills, clinical behaviour, self-efficacy and satisfaction. Seven databases were searched for randomised controlled trials (RCTs) from January 2000 to June 2015. Two independent reviewers rated trial quality and extracted trial data. Comparative effects were summarised as standardised mean differences (SMD) and 95% confidence intervals. Pooled effect sizes were calculated using a random-effects model for three contrasts of online versus (i) interactive workshops (ii) taught lectures and (iii) written/electronic manuals. We included 14 studies with a total of 1089 participants. Most trials studied medical professionals, used a workshop or lecture comparison, were of high risk of bias and had small sample sizes (range 21-183). Using the GRADE approach, we found low quality evidence that there was no difference between online training and an interactive workshop for clinical behaviour SMD 0.12 (95% CI -0.13 to 0.37). We found very low quality evidence of no difference between online methods and both a workshop and lecture for knowledge (workshop: SMD 0.04 (95% CI -0.28 to 0.36); lecture: SMD 0.22 (95% CI: -0.08, 0.51)). Lastly, compared to a manual (n = 3/14), we found very low quality evidence that online methods were superior for knowledge SMD 0.99 (95% CI 0.02 to 1.96). There were too few studies to draw any conclusions on the effects of online training for practical skills, self-efficacy, and satisfaction across all contrasts. It is likely that online methods may be as effective as alternative methods for training HCPs in clinical interventions for the outcomes of knowledge and clinical behaviour. However, the low quality of the evidence precludes drawing firm conclusions on the relative effectiveness of these training methods. Moreover, the confidence intervals around our effect sizes were large and could encompass important differences in effectiveness. More robust, adequately powered RCTs are needed.

Uncertainty estimation of Intensity-Duration-Frequency relationships: A regional analysis

NASA Astrophysics Data System (ADS)

Mélèse, Victor; Blanchet, Juliette; Molinié, Gilles

2018-03-01

We propose in this article a regional study of uncertainties in IDF curves derived from point-rainfall maxima. We develop two generalized extreme value models based on the simple scaling assumption, first in the frequentist framework and second in the Bayesian framework. Within the frequentist framework, uncertainties are obtained i) from the Gaussian density stemming from the asymptotic normality theorem of the maximum likelihood and ii) with a bootstrap procedure. Within the Bayesian framework, uncertainties are obtained from the posterior densities. We confront these two frameworks on the same database covering a large region of 100, 000 km2 in southern France with contrasted rainfall regime, in order to be able to draw conclusion that are not specific to the data. The two frameworks are applied to 405 hourly stations with data back to the 1980's, accumulated in the range 3 h-120 h. We show that i) the Bayesian framework is more robust than the frequentist one to the starting point of the estimation procedure, ii) the posterior and the bootstrap densities are able to better adjust uncertainty estimation to the data than the Gaussian density, and iii) the bootstrap density give unreasonable confidence intervals, in particular for return levels associated to large return period. Therefore our recommendation goes towards the use of the Bayesian framework to compute uncertainty.

Influence function for robust phylogenetic reconstructions.

PubMed

Bar-Hen, Avner; Mariadassou, Mahendra; Poursat, Marie-Anne; Vandenkoornhuyse, Philippe

2008-05-01

Based on the computation of the influence function, a tool to measure the impact of each piece of sampled data on the statistical inference of a parameter, we propose to analyze the support of the maximum-likelihood (ML) tree for each site. We provide a new tool for filtering data sets (nucleotides, amino acids, and others) in the context of ML phylogenetic reconstructions. Because different sites support different phylogenic topologies in different ways, outlier sites, that is, sites with a very negative influence value, are important: they can drastically change the topology resulting from the statistical inference. Therefore, these outlier sites must be clearly identified and their effects accounted for before drawing biological conclusions from the inferred tree. A matrix containing 158 fungal terminals all belonging to Chytridiomycota, Zygomycota, and Glomeromycota is analyzed. We show that removing the strongest outlier from the analysis strikingly modifies the ML topology, with a loss of as many as 20% of the internal nodes. As a result, estimating the topology on the filtered data set results in a topology with enhanced bootstrap support. From this analysis, the polyphyletic status of the fungal phyla Chytridiomycota and Zygomycota is reinforced, suggesting the necessity of revisiting the systematics of these fungal groups. We show the ability of influence function to produce new evolution hypotheses.

Structure and mechanics of aegagropilae fiber network.

PubMed

Verhille, Gautier; Moulinet, Sébastien; Vandenberghe, Nicolas; Adda-Bedia, Mokhtar; Le Gal, Patrice

2017-05-02

Fiber networks encompass a wide range of natural and manmade materials. The threads or filaments from which they are formed span a wide range of length scales: from nanometers, as in biological tissues and bundles of carbon nanotubes, to millimeters, as in paper and insulation materials. The mechanical and thermal behavior of these complex structures depends on both the individual response of the constituent fibers and the density and degree of entanglement of the network. A question of paramount importance is how to control the formation of a given fiber network to optimize a desired function. The study of fiber clustering of natural flocs could be useful for improving fabrication processes, such as in the paper and textile industries. Here, we use the example of aegagropilae that are the remains of a seagrass ( Posidonia oceanica ) found on Mediterranean beaches. First, we characterize different aspects of their structure and mechanical response, and second, we draw conclusions on their formation process. We show that these natural aggregates are formed in open sea by random aggregation and compaction of fibers held together by friction forces. Although formed in a natural environment, thus under relatively unconstrained conditions, the geometrical and mechanical properties of the resulting fiber aggregates are quite robust. This study opens perspectives for manufacturing complex fiber network materials.

The validity and scalability of the Theory of Mind Scale with toddlers and preschoolers.

PubMed

Hiller, Rachel M; Weber, Nathan; Young, Robyn L

2014-12-01

Despite the importance of theory of mind (ToM) for typical development, there remain 2 key issues affecting our ability to draw robust conclusions. One is the continued focus on false belief as the sole measure of ToM. The second is the lack of empirically validated measures of ToM as a broad construct. Our key aim was to examine the validity and reliability of the 5-item ToM scale (Peterson, Wellman, & Liu, 2005). In particular, we extended on previous research of this scale by assessing its scalability and validity for use with children from 2 years of age. Sixty-eight typically developing children (aged 24 to 61 months) were assessed on the scale's 5 tasks, along with a sixth Sally-Anne false-belief task. Our data replicated the scalability of the 5 tasks for a Rasch-but not Guttman-scale. Guttman analysis showed that a 4-item scale may be more suitable for this age range. Further, the tasks showed good internal consistency and validity for use with children as young as 2 years of age. Overall, the measure provides a valid and reliable tool for the assessment of ToM, and in particular, the longitudinal assessment of this ability as a construct. (c) 2014 APA, all rights reserved.

Pharmacoepidemiology for nephrologists: do proton pump inhibitors cause chronic kidney disease?

PubMed Central

Tomlinson, Laurie A.; Fogarty, Damian G.; Douglas, Ian; Nitsch, Dorothea

2017-01-01

Abstract Pharmacoepidemiology studies are increasingly used for research into safe prescribing in chronic kidney disease (CKD). Typically, patients prescribed a drug are compared with patients who are not on the drug and outcomes are compared to draw conclusions about the drug effects. This review article aims to provide the reader with a framework to critically appraise such research. A key concern in pharmacoepidemiology studies is confounding, in that patients who have worse health status are prescribed more drugs or different agents and their worse outcomes are attributed to the drugs not the health status. It may be challenging to adjust for this using statistical methods unless a comparison group with a similar health status but who are prescribed a different (comparison) drug(s) is identified. Another challenge in pharmacoepidemiology is outcome misclassification, as people who are more ill engage more often with the health service, leading to earlier diagnosis in people who are frequent attenders. Finally, using replication cohorts with the same methodology in the same type of health system does not ensure that findings are more robust. We use two recent papers that investigated the association of proton pump inhibitor drugs with CKD as a device to review the main pitfalls of pharmacoepidemiology studies and how to attempt to mitigate against potential biases that can occur. PMID:28201528

Burn patients' return to daily activities and participation as defined by the International Classification of Functioning, Disability and Health: A systematic review.

PubMed

Osborne, Candice L; Meyer, Walter J; Ottenbacher, Kenneth J; Arcari, Christine M

2017-06-01

The World Health Organization's International Classification of Functioning, Disability and Health (ICF) is a universal classification system of health and health-related domains. The ICF has been successfully applied to a wide range of health conditions and diseases; however, its application in the field of burn recovery has been minimal. This systematic review uses the domains of the ICF component 'activities and participation' to explore: (1) the extent to which return to daily activities and community participation after burn has been examined in the pediatric population, (2) the most common assessments used to determine activity and participation outcomes, and (3) what activity and participation areas are most affected in the pediatric burn population after discharge from acute care. Results determined that it is difficult to draw overarching conclusions in the area of return to 'activities and participation' for children with burn based on the paucity of current evidence. Of the studies conducted, few examined the same subtopics or used similar measurements. This suggests a need for more robust studies in this area in order to inform and improve burn rehabilitation practices to meet the potential needs of burn patients beyond an acute care setting. Copyright © 2016 Elsevier Ltd and ISBI. All rights reserved.

Destigmatization and Health: Cultural Constructions and the Long-Term Reduction of Stigma

PubMed Central

Clair, Matthew; Daniel, Caitlin

2017-01-01

Research on the societal-level causes and consequences of stigma has rarely considered the social conditions that account for destigmatization, the process by which a group’s worth and status improve. Destigmatization has important implications for the health of stigmatized groups. Building on a robust line of stigma reduction literature in psychology, we develop a sociological framework for understanding how new cultural constructions that draw equivalences and remove blame shape public and structural stigma over time. We examine historical transformations of cultural constructions surrounding three stigmatized groups in the United States: people living with HIV/AIDS, African Americans, and people labeled as obese. By tracing this process across cases, we find that the conditions that account for destigmatization include the credibility of new constructions, the status and visibility of actors carrying these constructions, the conclusiveness of expert knowledge about stigmatized groups, the interaction between new constructions and existing cultural ideologies, and the perceived linked fate of the stigmatized and dominant groups. We also find that the reduction of structural and public forms of stigma often depend on distinct processes and constructions. To conclude, we propose a framework for the comparative study of destigmatization as an essential component of promoting a culture of health. PMID:27020492

Culture, perception, and artistic visualization: a comparative study of children's drawings in three Siberian cultural groups.

PubMed

Istomin, Kirill V; Panáková, Jaroslava; Heady, Patrick

2014-01-01

In a study of three indigenous and non-indigenous cultural groups in northwestern and northeastern Siberia, framed line tests and a landscape drawing task were used to examine the hypotheses that test-based assessments of context sensitivity and independence are correlated with the amount of contextual information contained in drawings, and with the order in which the focal and background objects are drawn. The results supported these hypotheses, and inspection of the regression relationships suggested that the intergroup variations in test performance were likely to result from differences in the attention accorded to contextual information, as revealed by the drawings. Social and environmental explanations for the group differences in context sensitivity are also discussed. The conclusions support the argument that cultural differences in artistic styles and perceptual tests reflect the same underlying perceptual tendencies, and they are consistent with the argument that these tendencies reflect corresponding differences in patterns of social and environmental interaction. Copyright © 2013 Cognitive Science Society, Inc.

Robust Design of Sheet Metal Forming Process Based on Kriging Metamodel

NASA Astrophysics Data System (ADS)

Xie, Yanmin

2011-08-01

Nowadays, sheet metal forming processes design is not a trivial task due to the complex issues to be taken into account (conflicting design goals, complex shapes forming and so on). Optimization methods have also been widely applied in sheet metal forming. Therefore, proper design methods to reduce time and costs have to be developed mostly based on computer aided procedures. At the same time, the existence of variations during manufacturing processes significantly may influence final product quality, rendering non-robust optimal solutions. In this paper, a small size of design of experiments is conducted to investigate how a stochastic behavior of noise factors affects drawing quality. The finite element software (LS_DYNA) is used to simulate the complex sheet metal stamping processes. The Kriging metamodel is adopted to map the relation between input process parameters and part quality. Robust design models for sheet metal forming process integrate adaptive importance sampling with Kriging model, in order to minimize impact of the variations and achieve reliable process parameters. In the adaptive sample, an improved criterion is used to provide direction in which additional training samples can be added to better the Kriging model. Nonlinear functions as test functions and a square stamping example (NUMISHEET'93) are employed to verify the proposed method. Final results indicate application feasibility of the aforesaid method proposed for multi-response robust design.

Catalytic Chemistry.

ERIC Educational Resources Information Center

Borer, Londa; And Others

1996-01-01

Describes an approach for making chemistry relevant to everyday life. Involves the study of kinetics using the decomposition of hydrogen peroxide by vegetable juices. Allows students to design and carry out experiments and then draw conclusions from their results. (JRH)

Exploring students' conceptions of science learning via drawing: a cross-sectional analysis

NASA Astrophysics Data System (ADS)

Hsieh, Wen-Min; Tsai, Chin-Chung

2017-02-01

This cross-sectional study explored students' conceptions of science learning via drawing analysis. A total of 906 Taiwanese students in 4th, 6th, 8th, 10th, and 12th grade were asked to use drawing to illustrate how they conceptualise science learning. Students' drawings were analysed using a coding checklist to determine the presence or absence of specified attributes. Data analysis showed that the majority of students pictured science learning as school-based, involving certain types of experiment or teacher lecturing. In addition, notable cross-sectional differences were found in the 'Activity' and 'Emotions and attitudes' categories in students' drawings. Three major findings were made: (1) lower grade level students conceptualised science learning with a didactic approach, while higher graders might possess a quantitative view of science learning (i.e. how much is learned, not how well it is learned), (2) students' positive and negative emotions and attitudes toward science learning reversed around middle school, and (3) female students expressed significantly more positive emotions and attitudes than their male counterparts. In conclusion, higher graders' unfruitful conceptions of science learning warrant educators' attention. Moreover, further investigation of girls' more positive emotions and attitudes found in this study is needed.

Solar differential rotation in the period 1964-2016 determined by the Kanzelhöhe data set

NASA Astrophysics Data System (ADS)

Poljančić Beljan, I.; Jurdana-Šepić, R.; Brajša, R.; Sudar, D.; Ruždjak, D.; Hržina, D.; Pötzi, W.; Hanslmeier, A.; Veronig, A.; Skokić, I.; Wöhl, H.

2017-10-01

Context. Kanzelhöhe Observatory for Solar and Environmental Research (KSO) provides daily multispectral synoptic observations of the Sun using several telescopes. In this work we made use of sunspot drawings and full disk white light CCD images. Aims: The main aim of this work is to determine the solar differential rotation by tracing sunspot groups during the period 1964-2016, using the KSO sunspot drawings and white light images. We also compare the differential rotation parameters derived in this paper from the KSO with those collected fromf other data sets and present an investigation of the north - south rotational asymmetry. Methods: Two procedures for the determination of the heliographic positions were applied: an interactive procedure on the KSO sunspot drawings (1964-2008, solar cycles Nos. 20-23) and an automatic procedure on the KSO white light images (2009-2016, solar cycle No. 24). For the determination of the synodic angular rotation velocities two different methods have been used: a daily shift (DS) method and a robust linear least-squares fit (rLSQ) method. Afterwards, the rotation velocities had to be converted from synodic to sidereal, which were then used in the least-squares fitting for the solar differential rotation law. A comparison of the interactive and automatic procedures was performed for the year 2014. Results: The interactive procedure of position determination is fairly accurate but time consuming. In the case of the much faster automatic procedure for position determination, we found the rLSQ method for calculating rotational velocities to be more reliable than the DS method. For the test data from 2014, the rLSQ method gives a relative standard error for the differential rotation parameter B that is three times smaller than the corresponding relative standard error derived for the DS method. The best fit solar differential rotation profile for the whole time period is ω(b) = (14.47 ± 0.01)-(2.66 ± 0.10)sin2b (deg/day) for the DS method and ω(b) = (14.50 ± 0.01)-(2.87 ± 0.12)sin2b (deg/day) for the rLSQ method. A barely noticeable north - south asymmetry is observed for the whole time period 1964-2016 in the present paper. Rotation profiles, using different data sets, presented by other authors for the same time periods and the same tracer types, are in good agreement with our results. Conclusions: The KSO data set used in this paper is in good agreement with the Debrecen Photoheliographic Data and Greenwich Photoheliographic Results and is suitable for the investigation of the long-term variabilities in the solar rotation profile. Also, the quality of the KSO sunspot drawings has gradually increased during the last 50 yr.

Diversity-based reasoning in children.

PubMed

Heit, E; Hahn, U

2001-12-01

One of the hallmarks of inductive reasoning by adults is the diversity effect, namely that people draw stronger inferences from a diverse set of evidence than from a more homogenous set of evidence. However, past developmental work has not found consistent diversity effects with children age 9 and younger. We report robust sensitivity to diversity in children as young as 5, using everyday stimuli such as pictures of objects with people. Experiment 1 showed the basic diversity effect in 5- to 9-year-olds. Experiment 2 showed that, like adults, children restrict their use of diversity information when making inferences about remote categories. Experiment 3 used other stimulus sets to overcome an alternate explanation in terms of sample size rather than diversity effects. Finally, Experiment 4 showed that children more readily draw on diversity when reasoning about objects and their relations with people than when reasoning about objects' internal, hidden properties, thus partially explaining the negative findings of previous work. Relations to cross-cultural work and models of induction are discussed. Copyright 2001 Academic Press.

A Robust Adaptive Autonomous Approach to Optimal Experimental Design

NASA Astrophysics Data System (ADS)

Gu, Hairong

Experimentation is the fundamental tool of scientific inquiries to understand the laws governing the nature and human behaviors. Many complex real-world experimental scenarios, particularly in quest of prediction accuracy, often encounter difficulties to conduct experiments using an existing experimental procedure for the following two reasons. First, the existing experimental procedures require a parametric model to serve as the proxy of the latent data structure or data-generating mechanism at the beginning of an experiment. However, for those experimental scenarios of concern, a sound model is often unavailable before an experiment. Second, those experimental scenarios usually contain a large number of design variables, which potentially leads to a lengthy and costly data collection cycle. Incompetently, the existing experimental procedures are unable to optimize large-scale experiments so as to minimize the experimental length and cost. Facing the two challenges in those experimental scenarios, the aim of the present study is to develop a new experimental procedure that allows an experiment to be conducted without the assumption of a parametric model while still achieving satisfactory prediction, and performs optimization of experimental designs to improve the efficiency of an experiment. The new experimental procedure developed in the present study is named robust adaptive autonomous system (RAAS). RAAS is a procedure for sequential experiments composed of multiple experimental trials, which performs function estimation, variable selection, reverse prediction and design optimization on each trial. Directly addressing the challenges in those experimental scenarios of concern, function estimation and variable selection are performed by data-driven modeling methods to generate a predictive model from data collected during the course of an experiment, thus exempting the requirement of a parametric model at the beginning of an experiment; design optimization is performed to select experimental designs on the fly of an experiment based on their usefulness so that fewest designs are needed to reach useful inferential conclusions. Technically, function estimation is realized by Bayesian P-splines, variable selection is realized by Bayesian spike-and-slab prior, reverse prediction is realized by grid-search and design optimization is realized by the concepts of active learning. The present study demonstrated that RAAS achieves statistical robustness by making accurate predictions without the assumption of a parametric model serving as the proxy of latent data structure while the existing procedures can draw poor statistical inferences if a misspecified model is assumed; RAAS also achieves inferential efficiency by taking fewer designs to acquire useful statistical inferences than non-optimal procedures. Thus, RAAS is expected to be a principled solution to real-world experimental scenarios pursuing robust prediction and efficient experimentation.

Identification and robust control of an experimental servo motor.

PubMed

Adam, E J; Guestrin, E D

2002-04-01

In this work, the design of a robust controller for an experimental laboratory-scale position control system based on a dc motor drive as well as the corresponding identification and robust stability analysis are presented. In order to carry out the robust design procedure, first, a classic closed-loop identification technique is applied and then, the parametrization by internal model control is used. The model uncertainty is evaluated under both parametric and global representation. For the latter case, an interesting discussion about the conservativeness of this description is presented by means of a comparison between the uncertainty disk and the critical perturbation radius approaches. Finally, conclusions about the performance of the experimental system with the robust controller are discussed using comparative graphics of the controlled variable and the Nyquist stability margin as a robustness measurement.

77 FR 27066 - Proposed Data Collections Submitted for Public Comment and Recommendations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-08

... by Nimer and Lundahl (2007) in finding multiple studies with poor research designs and other methodological problems that made it hard for those authors to draw firm conclusions. Even where studies focused...

A universal test for gravitational decoherence

PubMed Central

Pfister, C.; Kaniewski, J.; Tomamichel, M.; Mantri, A.; Schmucker, R.; McMahon, N.; Milburn, G.; Wehner, S.

2016-01-01

Quantum mechanics and the theory of gravity are presently not compatible. A particular question is whether gravity causes decoherence. Several models for gravitational decoherence have been proposed, not all of which can be described quantum mechanically. Since quantum mechanics may need to be modified, one may question the use of quantum mechanics as a calculational tool to draw conclusions from the data of experiments concerning gravity. Here we propose a general method to estimate gravitational decoherence in an experiment that allows us to draw conclusions in any physical theory where the no-signalling principle holds, even if quantum mechanics needs to be modified. As an example, we propose a concrete experiment using optomechanics. Our work raises the interesting question whether other properties of nature could similarly be established from experimental observations alone—that is, without already having a rather well-formed theory of nature to make sense of experimental data. PMID:27694976

Exploratory Study of 4D Versus 3D Robust Optimization in Intensity-Modulated Proton Therapy for Lung Cancer

PubMed Central

Liu, Wei; Schild, Steven E.; Chang, Joe Y.; Liao, Zhongxing; Chang, Yu-Hui; Wen, Zhifei; Shen, Jiajian; Stoker, Joshua B.; Ding, Xiaoning; Hu, Yanle; Sahoo, Narayan; Herman, Michael G.; Vargas, Carlos; Keole, Sameer; Wong, William; Bues, Martin

2015-01-01

Background To compare the impact of uncertainties and interplay effect on 3D and 4D robustly optimized intensity-modulated proton therapy (IMPT) plans for lung cancer in an exploratory methodology study. Methods IMPT plans were created for 11 non-randomly selected non-small-cell lung cancer (NSCLC) cases: 3D robustly optimized plans on average CTs with internal gross tumor volume density overridden to irradiate internal target volume, and 4D robustly optimized plans on 4D CTs to irradiate clinical target volume (CTV). Regular fractionation (66 Gy[RBE] in 33 fractions) were considered. In 4D optimization, the CTV of individual phases received non-uniform doses to achieve a uniform cumulative dose. The root-mean-square-dose volume histograms (RVH) measured the sensitivity of the dose to uncertainties, and the areas under the RVH curve (AUCs) were used to evaluate plan robustness. Dose evaluation software modeled time-dependent spot delivery to incorporate interplay effect with randomized starting phases of each field per fraction. Dose-volume histogram indices comparing CTV coverage, homogeneity, and normal tissue sparing were evaluated using Wilcoxon signed-rank test. Results 4D robust optimization plans led to smaller AUC for CTV (14.26 vs. 18.61 (p=0.001), better CTV coverage (Gy[RBE]) [D95% CTV: 60.6 vs 55.2 (p=0.001)], and better CTV homogeneity [D5%–D95% CTV: 10.3 vs 17.7 (p=0.002)] in the face of uncertainties. With interplay effect considered, 4D robust optimization produced plans with better target coverage [D95% CTV: 64.5 vs 63.8 (p=0.0068)], comparable target homogeneity, and comparable normal tissue protection. The benefits from 4D robust optimization were most obvious for the 2 typical stage III lung cancer patients. Conclusions Our exploratory methodology study showed that, compared to 3D robust optimization, 4D robust optimization produced significantly more robust and interplay-effect-resistant plans for targets with comparable dose distributions for normal tissues. A further study with a larger and more realistic patient population is warranted to generalize the conclusions. PMID:26725727

Analyzing prospective teachers' images of scientists using positive, negative and stereotypical images of scientists

NASA Astrophysics Data System (ADS)

Subramaniam, Karthigeyan; Esprívalo Harrell, Pamela; Wojnowski, David

2013-04-01

Background and purpose : This study details the use of a conceptual framework to analyze prospective teachers' images of scientists to reveal their context-specific conceptions of scientists. The conceptual framework consists of context-specific conceptions related to positive, stereotypical and negative images of scientists as detailed in the literature on the images, role and work of scientists. Sample, design and method : One hundred and ninety-six drawings of scientists, generated by prospective teachers, were analyzed using the Draw-A-Scientist-Test Checklist (DAST-C), a binary linear regression and the conceptual framework. Results : The results of the binary linear regression analysis revealed a statistically significant difference for two DAST-C elements: ethnicity differences with regard to drawing a scientist who was Caucasian and gender differences for indications of danger. Analysis using the conceptual framework helped to categorize the same drawings into positive, stereotypical, negative and composite images of a scientist. Conclusions : The conceptual framework revealed that drawings were focused on the physical appearance of the scientist, and to a lesser extent on the equipment, location and science-related practices that provided the context of a scientist's role and work. Implications for teacher educators include the need to understand that there is a need to provide tools, like the conceptual framework used in this study, to help prospective teachers to confront and engage with their multidimensional perspectives of scientists in light of the current trends on perceiving and valuing scientists. In addition, teacher educators need to use the conceptual framework, which yields qualitative perspectives about drawings, together with the DAST-C, which yields quantitative measure for drawings, to help prospective teachers to gain a holistic outlook on their drawings of scientists.

On Blowing Trumpets to the Tulips: To Prove or Not to Prove the Null Hypothesis--Comment on Bosch, Steinkamp, and Boller (2006)

ERIC Educational Resources Information Center

Wilson, David B.; Shadish, William R.

2006-01-01

The H. Bosch, F. Steinkamp, and E. Boller (see record 2006-08436-001) meta-analysis reaches mixed and cautious conclusions about the possibility of psychokinesis. The authors argue that, for both methodological and philosophical reasons, it is nearly impossible to draw any conclusions from this body of research. The authors do not agree that any…

If We Don’t, Who Will? The Employment of the United States Army to Combat Potential Pandemic Outbreaks in West Africa

DTIC Science & Technology

2015-06-12

27 viii Threats to Validity and Biases ...draw conclusions and make recommendations for future research. Threats to Validity and Biases There are a several issues that pose a threat to...validity and bias to the research. Threats to validity affect the accuracy of the research and soundness of the conclusion. Threats to external validity

Ex-Huming an Old Issue.

ERIC Educational Resources Information Center

Brown, Robert T.; Jackson, Lee A.

1992-01-01

Reviews research on inductive reasoning errors, including seeing patterns or relationships where none exist, neglecting statistical regression, overgeneralizing unrepresentative data, and drawing conclusions based on incomplete decision matrices. Considers "false consensus effect," through which associations with like-minded people lead one to…

Preschool Age Populations Research Needs - NCS Dietary Assessment Literature Review

Cancer.gov

Drawing conclusions from the validation studies on preschool populations discussed in this chapter is difficult because of the varied study designs, the relatively small study populations, and limited number of studies on each dietary assessment method.

Older adults’ attitudes toward noncompetent subjects participating in Alzheimers research

PubMed Central

Karlawish, Jason; Rubright, Jonathan; Casarett, David; Cary, Mark; TenHave, Thomas; Sankar, Pamela

2008-01-01

Objective Since research that enrolls noncompetent patients with Alzheimers disease and does not present potential benefit to subjects is the source of substantial ethical controversy, we assessed willingness to have a proxy for research decision making, and, for each of two Alzheimers disease biomarker studies (minimal risk blood draw and a greater than minimal risk blood draw and lumbar puncture), willingness to grant an advance consent, and willingness to grant a proxy leeway over advance consent. Methods Face to face survey of 538 persons 65 and over who resided in the Southeastern Pennsylvania region Results The majority 83% (445/538) granted advance consent to a blood draw study and nearly half to a blood draw plus lumbar puncture 259 (48%). Most persons (96%) were willing to identify a proxy for research decision making and most were willing to grant their proxy leeway over their advance consent: blood draw 434 (81%), and 375 (70%) blood draw plus lumbar puncture. Combining the preferences for advance consent and leeway, the proportion who would permit being enrolled in the blood draw and spinal fluid sample studies were, respectively, 92% (497/538) and 75% (404/538). Multi-variate models showed that willingness to be enrolled in research was most strongly associated with a favorable attitude about biomedical research. Conclusions Older adults generally support enrolling noncompetent persons with Alzheimers disease into research that does not present a benefit to subjects. Willingness to grant their proxy leeway over advance consent and a favorable attitude about biomedical research substantially explain this willingness. PMID:18923066

Analysis of the Variations in Rock Magnetic Properties of the Quaternary Blackwater Draw (Eolian) Formation, West Texas

NASA Astrophysics Data System (ADS)

Stine, J. M.; Ferguson, J. F.; Geissman, J. W.; Sweet, D. E.

2017-12-01

The Quaternary Blackwater Draw Formation consists of the surficial deposits ( 10 + m thick) that directly overlie the Neogene Ogallala Formation in the Southern High Plains (SHP). These Quaternary deposits display a rhythmic pattern where eolian derived sediments (loess) are in turn punctuated by several paleosol layers, implying that Quaternary glacial-interglacial climate cycles are recorded in the Blackwater Draw Formation. In order to investigate this hypothesis, several rock magnetic parameters obtained from the Blackwater Draw Formation were analyzed using exploratory data analysis (EDA) techniques. The Blackwater Draw Formation was sampled at high resolution (2.5-5 cm intervals in depth, which serves as a proxy for time). Rock magnetic parameters measured are bulk magnetic susceptibility (χ, median: 1.56 * 10-4 SI volume), anhysteretic remanent magnetization (ARM, median: 0.1612 A/m), and isothermal remanent magnetization (IRM, median: 2.5367 A/m) intensity, which allow for the determination of two common environmental magnetic ratios (ARM/χ and ARM/IRM, medians: 1051 and 0.068 respectively) that are often used to approximate magnetic grain size. The data were analyzed using robust EDA methods for classification, correlation, and signal extraction. Using these techniques, it becomes evident that a good correspondence exists between the geophysical data and the geologic model (stratigraphy). For example, the cross plots showed that the magnetic data segregate into clusters corresponding to stratigraphy. Smoothing of the magnetic ratio data produces an oscillatory signal that may correspond to climate cyclicity. Additionally the smoothed models show a noticeable change in periodicity, where the ARM, IRM and χ values in the uppermost section exhibit a much higher amplitude and lower frequency than the bottom part of the section (with the reverse being true for the ratios). When comparing the data to the geologic model this change appears to correlate with the Mid-Pleistocene Transition (MPT), when the Earth's climate cycle periodicity changed from 41 ka to 100 ka.

The effect of abdominal drawing-in exercise and myofascial release on pain, flexibility, and balance of elderly females.

PubMed

Yu, Seong Hun; Sim, Yong Hyeon; Kim, Myung Hoon; Bang, Ju Hee; Son, Kyung Hyun; Kim, Jae Woong; Kim, Hyun Jin

2016-10-01

[Purpose] This study is designed to compare the effects of abdominal drawing-in exercise and myofascial release on pain, flexibility, and balance of elderly females. [Subjects and Methods] Forty elderly females aged 65 or older who had complained of low back pain for three months or longer were selected as the subjects. They were randomly and equally assigned to either an abdominal drawing-in group or a myofascial release group. The subjects conducted exercise three times per week, 40 minutes each time, for eight weeks. As evaluation tools, visual analogue scale for pain, remodified schober test for flexibility, and upright posture with eye opening on hard platform, upright posture with eye closing on hard platform, upright posture with eye opening on soft platform, upright posture with eye closing on soft platform using tetrax for balance were used. [Results] The abdominal drawing-in exercise group saw significant difference in pain and balance after the exercise compared to before the exercise. The myofascial release group saw significant difference in pain and flexibility after exercise compared to before the exercise. [Conclusion] The above study showed that abdominal drawing-in exercise affected elderly females regarding pain and balance and myofascial release influenced their pain and flexibility.

Improved Necker Cube Drawing-Based Assessment Battery for Constructional Apraxia: The Mie Constructional Apraxia Scale (MCAS)

PubMed Central

Satoh, Masayuki; Mori, Chika; Matsuda, Kana; Ueda, Yukito; Tabei, Ken-ichi; Kida, Hirotaka; Tomimoto, Hidekazu

2016-01-01

Background/Aims Constructional apraxia (CA) is usually diagnosed by having patients draw figures; however, the reported assessments only evaluate the drawn figure. We designed a new assessment battery for CA (the Mie Constructional Apraxia Scale, MCAS) which includes both the shape and drawing process, and investigated its utility against other assessment methods. Methods We designed the MCAS, and evaluated inter- and intrarater reliability. We also investigated the sensitivity, specificity, and positive and negative predictive values in dementia patients, and compared MCAS assessment with other reported batteries in the same subjects. Results Moderate interrater reliability was shown for speech therapists with limited experience. Moderate to substantial intrarater reliability was shown several weeks after initial assessment. When cutoff scores and times were set at 2/3 points and 39/40 s, sensitivity and specificity were 77.1 and 70.4%, respectively, with positive and negative predictive values of 80.0 and 66.7%, respectively. Dementia patients had significantly worse scores and times for Necker cube drawing than an elderly control group on the MCAS, and on other assessments. Conclusions We conclude that the MCAS, which includes both the assessment of the drawn Necker cube shape and the drawing process, is useful for detecting even mild CA. PMID:27790241

Leonardo da Vinci and Andreas Vesalius; the shoulder girdle and the spine, a comparison.

PubMed

Ganseman, Y; Broos, P

2008-01-01

Leonardo Da Vinci and Andreas Vesalius were two important renaissance persons; Vesalius was a surgeon-anatomist who delivered innovative work on the study of the human body, Leonardo da Vinci was an artist who delivered strikingly accurate and beautiful drawings on the human body. Below we compare both masters with regard to their knowledge of the working of the muscles, their method and system of dissection and their system and presentation of the drawings. The investigation consisted of a comparison between both anatomists, in particular concerning their study on the shoulder girdle and spine, by reviewing their original work as well as already existing literature on this subject. The investigation led to the conclusion that the drawings mentioned meant a change in history, and were of high quality, centuries ahead of their time. Both were anatomists, both were revolutionary, only one changed history at the moment itself, while the other changed history centuries later. Leonardo has made beautiful drawings that are at a match with the drawings of today or are even better. Vesalius set the start for medicine as a science as it is until this day. Their lives differed as strongly as their impact. In the light of their time, the achievement they made was extraordinary.

Chemical Data Reporting Fact Sheet: Chemicals Snapshot

EPA Pesticide Factsheets

This fact sheet provides a brief overview of the chemical manufacturing, processing, and use information collected for the 2012 Chemical Data Reporting (CDR) rule. Users do not have access to the complete CDR data set and should draw conclusions with care.

USE OF SCALE INVARIANCE IN EVALUATING JUDGEMENT INDICATORS

EPA Science Inventory

Indicators are used to draw conclusions about ecological endpoints when these endpoints cannot be measured directly. In many cases, inference about an endpoint are only possible because assumptions have been made about the relationship between indicator and endpoint; we refer to ...

From Stats to Stage-Translational Research in Performing Arts Medicine.

PubMed

Ackermann, Bronwen J

2016-12-01

Medical Problems of Performing Artists, since its inception under the legendary Alice Brandfonbrener's guidance and vision, has always recognized the need for voices to be heard from the clinic, stage, and experimental research. This has been important in a relatively young field like performing arts medicine, where there is not yet a robust base of evidence to draw from for the complex range of physical, psychological, and institutional challenges that can affect performer health. Evidence-based medicine has long been described as using the best available research in conjunction with clinical expertise, while considering patient beliefs, characteristics, and circumstances.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The 21st Century Power Partnership's program in Mexico (21CPP Mexico) is one initiative of the Clean Energy Ministerial, carried out in cooperation with government and local stakeholders, drawing upon an international community of power system expertise. The overall goal of this program is to support Mexico's power system transformation by accelerating the transition to a reliable, financially robust, and low-carbon system. 21CPP Mexico activities focus on achieving positive outcomes for all participants, especially addressing critical questions and challenges facing policymakers, regulators, and system operators. In support of this goal, 21CPP Mexico taps into deep networks of expertise and professional connections.

Viewing equitable practices through the lens of intersecting identities

NASA Astrophysics Data System (ADS)

Lyons, Renée; Dsouza, Nikeetha; Quigley, Cassie

2016-12-01

This review explores Archer, Dawson, Seakins, and Wong's "Disorienting, fun or meaningful? Disadvantaged families' experiences of a science museum visit" by examining the analytic frameworks guiding this study. To expand on Archer et al.'s use of feminist post-structuralist theories of identity we draw from the theory of intersectionality to provide a more robust framework for analyzing barriers to engagement within an informal learning space. Our response to this work ends by exploring the types of solutions generated from an intersectionality framework—solutions aimed at transforming institutional programs and practices to create more equitable spaces for learning.

Selective robust optimization: A new intensity-modulated proton therapy optimization strategy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Yupeng; Niemela, Perttu; Siljamaki, Sami

2015-08-15

Purpose: To develop a new robust optimization strategy for intensity-modulated proton therapy as an important step in translating robust proton treatment planning from research to clinical applications. Methods: In selective robust optimization, a worst-case-based robust optimization algorithm is extended, and terms of the objective function are selectively computed from either the worst-case dose or the nominal dose. Two lung cancer cases and one head and neck cancer case were used to demonstrate the practical significance of the proposed robust planning strategy. The lung cancer cases had minimal tumor motion less than 5 mm, and, for the demonstration of the methodology,more » are assumed to be static. Results: Selective robust optimization achieved robust clinical target volume (CTV) coverage and at the same time increased nominal planning target volume coverage to 95.8%, compared to the 84.6% coverage achieved with CTV-based robust optimization in one of the lung cases. In the other lung case, the maximum dose in selective robust optimization was lowered from a dose of 131.3% in the CTV-based robust optimization to 113.6%. Selective robust optimization provided robust CTV coverage in the head and neck case, and at the same time improved controls over isodose distribution so that clinical requirements may be readily met. Conclusions: Selective robust optimization may provide the flexibility and capability necessary for meeting various clinical requirements in addition to achieving the required plan robustness in practical proton treatment planning settings.« less

Constitutive Behavior and Deep Drawability of Three Aluminum Alloys Under Different Temperatures and Deformation Speeds

NASA Astrophysics Data System (ADS)

Panicker, Sudhy S.; Prasad, K. Sajun; Basak, Shamik; Panda, Sushanta Kumar

2017-08-01

In the present work, uniaxial tensile tests were carried out to evaluate the stress-strain response of AA2014, AA5052 and AA6082 aluminum alloys at four temperatures: 303, 423, 523 and 623 K, and three strain rates: 0.0022, 0.022 and 0.22 s-1. It was found that the Cowper-Symonds model was not a robust constitutive model, and it failed to predict the flow behavior, particularly the thermal softening at higher temperatures. Subsequently, a comparative study was made on the capability of Johnson-Cook (JC), modified Zerilli-Armstrong (m-ZA), modified Arrhenius (m-ARR) and artificial neural network (ANN) for modeling the constitutive behavior of all the three aluminum alloys under the mentioned strain rates and temperatures. Also, the improvement in formability of the materials was evaluated at an elevated temperature of 623 K in terms of cup height and maximum safe strains by conducting cylindrical cup deep drawing experiments under two different punch speeds of 4 and 400 mm/min. The cup heights increased during warm deep drawing due to thermal softening and increase in failure strains. Also, a small reduction in cup height was observed when the punch speed increased from 4 to 400 mm/min at 623 K. Hence, it was suggested to use high-speed deformation at elevated temperature to reduce both punch load and cycle time during the deep drawing process.

Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing.

PubMed

Shah, Sheel; Lubeck, Eric; Schwarzkopf, Maayan; He, Ting-Fang; Greenbaum, Alon; Sohn, Chang Ho; Lignell, Antti; Choi, Harry M T; Gradinaru, Viviana; Pierce, Niles A; Cai, Long

2016-08-01

Accurate and robust detection of mRNA molecules in thick tissue samples can reveal gene expression patterns in single cells within their native environment. Preserving spatial relationships while accessing the transcriptome of selected cells is a crucial feature for advancing many biological areas - from developmental biology to neuroscience. However, because of the high autofluorescence background of many tissue samples, it is difficult to detect single-molecule fluorescence in situ hybridization (smFISH) signals robustly in opaque thick samples. Here, we draw on principles from the emerging discipline of dynamic nucleic acid nanotechnology to develop a robust method for multi-color, multi-RNA imaging in deep tissues using single-molecule hybridization chain reaction (smHCR). Using this approach, single transcripts can be imaged using epifluorescence, confocal or selective plane illumination microscopy (SPIM) depending on the imaging depth required. We show that smHCR has high sensitivity in detecting mRNAs in cell culture and whole-mount zebrafish embryos, and that combined with SPIM and PACT (passive CLARITY technique) tissue hydrogel embedding and clearing, smHCR can detect single mRNAs deep within thick (0.5 mm) brain slices. By simultaneously achieving ∼20-fold signal amplification and diffraction-limited spatial resolution, smHCR offers a robust and versatile approach for detecting single mRNAs in situ, including in thick tissues where high background undermines the performance of unamplified smFISH. © 2016. Published by The Company of Biologists Ltd.

Robust Mokken Scale Analysis by Means of the Forward Search Algorithm for Outlier Detection

ERIC Educational Resources Information Center

Zijlstra, Wobbe P.; van der Ark, L. Andries; Sijtsma, Klaas

2011-01-01

Exploratory Mokken scale analysis (MSA) is a popular method for identifying scales from larger sets of items. As with any statistical method, in MSA the presence of outliers in the data may result in biased results and wrong conclusions. The forward search algorithm is a robust diagnostic method for outlier detection, which we adapt here to…

DNA-tagged Microparticles for Tracing Water Flows and Travel Times in Natural Systems: The First results from Controlled Laboratory Experiments

NASA Astrophysics Data System (ADS)

Bogaard, T.; Bandyopadhyay, S.; Foppen, J. W.

2017-12-01

Societal demand for water safety is continuously increasing, being it resilient against flood/droughts, clean water for ecosystems, recreation or safe drinking water. Robust methods to measure temporal and spatial patterns of water and contaminant pathways are still lacking. Our research project aims to develop and apply (1) innovative, robust, and environmental-friendly silica-protected iron oxide micro-particles tagged with artificial DNA to trace contaminant movement and travel times of water in natural systems and (2) an innovative coupled model approach to capture dynamics in hydrological pathways and their effects on water quality. The exceptional property of DNA-tagging is the infinite number of unique tracers that can be produced and their detectability at extreme low concentrations. The advantage of the iron-core of the particle is the magnetic harvesting of the particles from water-samples. Such tracers are thought to give the water sector a unique tool for in-situ mapping of transport of contaminants and pathogenic microorganisms in water systems. However, the characteristics of the particle like magnetic property of the iron-core and surface potential of the silica layer, are of key importance for the behaviour of the particle in surface water and in soils. Furthermore, the application of such micro-particles requires strict protocols for the experiment, sampling and laboratory handling which are currently not available. We used two different types of silica-protected DNA-tagged micro-particles. We performed batch, column and flow experiments to assess the behaviour of the particles. We will present the first results of the controlled laboratory experiments for hydrological tracing. We will discuss the results and link it to the differences in particles design. Furthermore, we will draw conclusions and discuss knowledge gaps for future application of silica-protected DNA-tagged micro-particles in hydrological research.

Skepticism and Denial: Drawing a line

NASA Astrophysics Data System (ADS)

Byrne, J. M.; Brown, M. B.; Peacock, K.

2016-12-01

Climate denialism is distinct from a merely skeptical attitude towards generally accepted views in climate science. But drawing the line between them takes care—there are similarities between skepticism and denial, including a shared reluctance to accept conclusions that nearly all qualified scientists take to be well-justified. Here we will explore both how to draw the line, and how to effectively communicate the differences between denial and skepticism. Identifying which of these two terms best describes someone's attitude turns on whether they reject a generally accepted view based on a `high threshold' for acceptance of conclusions in general, or from a preference that the conclusion in question be false. In most cases, denialism manifests in disregard and mistreatment of evidence, including selective quotation, credulous endorsement of bad sources and incredulous rejection of good sources. Historically, current accepted views became dominant as alternatives were excluded and arguments supporting current views accumulated. The accumulated record of evidence and successful application of those views sets a high bar for proposed alternatives to them. Pure skeptics may refuse to endorse generally accepted views without rejecting or distorting the strong evidence for those views, and typically support policy responses based on the implications of that evidence. But deniers who reject scientific conclusions reject the evidence for those views while endorsing views that a true skeptic would regard as less plausible and well-supported than the accepted views. Thus motivated cognition is the key to defining denial. Pascal's famous argument for belief in God illustrates the problem: even assuming God's existence to be extremely improbable, the expected value of believing is far higher than the expected value of disbelieving. But Pascal's argument undermines its own methodology: without reasons to rely on beliefs as reliable guides to successful action, cost-benefit calculations cannot be justified at all. The contribution of this work to the proposed course will aim to ensure students learn how the basic principles needed to understand anthropogenic warming emerged, and why those principles are solidly grounded.

Visualization of the Invisible, Explanation of the Unknown, Ruggedization of the Unstable: Sensitivity Analysis, Virtual Tryout and Robust Design through Systematic Stochastic Simulation

NASA Astrophysics Data System (ADS)

Zwickl, Titus; Carleer, Bart; Kubli, Waldemar

2005-08-01

In the past decade, sheet metal forming simulation became a well established tool to predict the formability of parts. In the automotive industry, this has enabled significant reduction in the cost and time for vehicle design and development, and has helped to improve the quality and performance of vehicle parts. However, production stoppages for troubleshooting and unplanned die maintenance, as well as production quality fluctuations continue to plague manufacturing cost and time. The focus therefore has shifted in recent times beyond mere feasibility to robustness of the product and process being engineered. Ensuring robustness is the next big challenge for the virtual tryout / simulation technology. We introduce new methods, based on systematic stochastic simulations, to visualize the behavior of the part during the whole forming process — in simulation as well as in production. Sensitivity analysis explains the response of the part to changes in influencing parameters. Virtual tryout allows quick exploration of changed designs and conditions. Robust design and manufacturing guarantees quality and process capability for the production process. While conventional simulations helped to reduce development time and cost by ensuring feasible processes, robustness engineering tools have the potential for far greater cost and time savings. Through examples we illustrate how expected and unexpected behavior of deep drawing parts may be tracked down, identified and assigned to the influential parameters. With this knowledge, defects can be eliminated or springback can be compensated e.g.; the response of the part to uncontrollable noise can be predicted and minimized. The newly introduced methods enable more reliable and predictable stamping processes in general.

An investigation of school violence through Turkish children's drawings.

PubMed

Yurtal, Filiz; Artut, Kazim

2010-01-01

This study investigates Turkish children's perception of violence in school as represented through drawings and narratives. In all, 66 students (12 to 13 years old) from the middle socioeconomic class participated. To elicit children's perception of violence, they were asked to draw a picture of a violent incident they had heard, experienced, or witnessed. Children mostly drew pictures of violent events among children (33 pictures). Also, there were pictures of violent incidents perpetrated by teachers and directors against children. It was observed that violence influenced children. Violence was mostly depicted in school gardens (38 pictures), but there were violent incidents everywhere, such as in classrooms, corridors, and school stores as well. Moreover, it was found that brute force was the most referred way of violence in the children's depictions (38 pictures). In conclusion, children clearly indicated that there was violence in schools and they were affected by it.

Math and the Mona Lisa

DOE Office of Scientific and Technical Information (OSTI.GOV)

Atalay, Bulent

2004-05-03

Bulent Atalay discusses content from his book entitled "Math and the Mona Lisa" which covers Leonardo Da Vinci and how he combined his love of science, math, and art to draw dramatic conclusions about the natural world. He also describes how mathematics influences art and architecture.

Macro Learning on a Micro Scale. Link Biology and Chemistry.

ERIC Educational Resources Information Center

Falk, Peter M.

1990-01-01

Described are several laboratory investigations that may be used to introduce biochemistry. Topics covered include carbohydrates, lipids, proteins, and metabolism. Reactions, stock solution formulas, and procedures are listed. Emphasized are individualizing work, designing alternative investigations, solving problems, and drawing conclusions. (KR)

The CTD Science Practical Survey.

ERIC Educational Resources Information Center

Bathory, Zoltan

1985-01-01

As part of Hungary's Curriculum Theory Department (CTD-80) assessment, 1,543 14-year-olds were tested in the performance of science experiments in physics and chemistry. Skills included observing, measuring, hypothesizing, and drawing conclusions. Results are presented, and implications for curriculum are suggested. (GDC)

Attitudes towards Refugee Education and Its Link to Xenophobia in the United States

ERIC Educational Resources Information Center

Campbell, James Adam, III

2017-01-01

This paper attempts to deconstruct the resistance among a majority of Americans to admit Syrian refugees. Using a survey of secondary and post-secondary students and faculty in New Mexico, I attempt to draw conclusions regarding this resistance.

Salient Point Detection in Protrusion Parts of 3D Object Robust to Isometric Variations

NASA Astrophysics Data System (ADS)

Mirloo, Mahsa; Ebrahimnezhad, Hosein

2018-03-01

In this paper, a novel method is proposed to detect 3D object salient points robust to isometric variations and stable against scaling and noise. Salient points can be used as the representative points from object protrusion parts in order to improve the object matching and retrieval algorithms. The proposed algorithm is started by determining the first salient point of the model based on the average geodesic distance of several random points. Then, according to the previous salient point, a new point is added to this set of points in each iteration. By adding every salient point, decision function is updated. Hence, a condition is created for selecting the next point in which the iterative point is not extracted from the same protrusion part so that drawing out of a representative point from every protrusion part is guaranteed. This method is stable against model variations with isometric transformations, scaling, and noise with different levels of strength due to using a feature robust to isometric variations and considering the relation between the salient points. In addition, the number of points used in averaging process is decreased in this method, which leads to lower computational complexity in comparison with the other salient point detection algorithms.

Can We Draw General Conclusions from Interval Training Studies?

PubMed

Viana, Ricardo Borges; de Lira, Claudio Andre Barbosa; Naves, João Pedro Araújo; Coswig, Victor Silveira; Del Vecchio, Fabrício Boscolo; Ramirez-Campillo, Rodrigo; Vieira, Carlos Alexandre; Gentil, Paulo

2018-04-19

Interval training (IT) has been used for many decades with the purpose of increasing performance and promoting health benefits while demanding a relatively small amount of time. IT can be defined as intermittent periods of intense exercise separated by periods of recovery and has been divided into high-intensity interval training (HIIT), sprint interval training (SIT), and repeated sprint training (RST). IT use has resulted in the publication of many studies and many of them with conflicting results and positions. The aim of this article was to move forward and understand the studies' protocols in order to draw accurate conclusions, as well as to avoid previous mistakes and effectively reproduce previous protocols. When analyzing the literature, we found many inconsistencies, such as the controversial concept of 'supramaximal' effort, a misunderstanding with regard to the term 'high intensity,' and the use of different strategies to control intensity. The adequate definition and interpretation of training intensity seems to be vital, since the results of IT are largely dependent on it. These observations are only a few examples of the complexity involved in IT prescription, and are discussed to illustrate some problems with the current literature regarding IT. Therefore, it is our opinion that it is not possible to draw general conclusions about IT without considering all variables used in IT prescription, such as exercise modality, intensity, effort and rest times, and participants' characteristics. In order to help guide researchers and health professionals in their practices it is important that experimental studies report their methods in as much detail as possible and future reviews and meta-analyses should critically discuss the articles included in the light of their methods to avoid inappropriate generalizations.

Exploratory Study of 4D versus 3D Robust Optimization in Intensity Modulated Proton Therapy for Lung Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Wei, E-mail: Liu.Wei@mayo.edu; Schild, Steven E.; Chang, Joe Y.

Purpose: The purpose of this study was to compare the impact of uncertainties and interplay on 3-dimensional (3D) and 4D robustly optimized intensity modulated proton therapy (IMPT) plans for lung cancer in an exploratory methodology study. Methods and Materials: IMPT plans were created for 11 nonrandomly selected non-small cell lung cancer (NSCLC) cases: 3D robustly optimized plans on average CTs with internal gross tumor volume density overridden to irradiate internal target volume, and 4D robustly optimized plans on 4D computed tomography (CT) to irradiate clinical target volume (CTV). Regular fractionation (66 Gy [relative biological effectiveness; RBE] in 33 fractions) was considered.more » In 4D optimization, the CTV of individual phases received nonuniform doses to achieve a uniform cumulative dose. The root-mean-square dose-volume histograms (RVH) measured the sensitivity of the dose to uncertainties, and the areas under the RVH curve (AUCs) were used to evaluate plan robustness. Dose evaluation software modeled time-dependent spot delivery to incorporate interplay effect with randomized starting phases of each field per fraction. Dose-volume histogram (DVH) indices comparing CTV coverage, homogeneity, and normal tissue sparing were evaluated using Wilcoxon signed rank test. Results: 4D robust optimization plans led to smaller AUC for CTV (14.26 vs 18.61, respectively; P=.001), better CTV coverage (Gy [RBE]) (D{sub 95%} CTV: 60.6 vs 55.2, respectively; P=.001), and better CTV homogeneity (D{sub 5%}-D{sub 95%} CTV: 10.3 vs 17.7, resspectively; P=.002) in the face of uncertainties. With interplay effect considered, 4D robust optimization produced plans with better target coverage (D{sub 95%} CTV: 64.5 vs 63.8, respectively; P=.0068), comparable target homogeneity, and comparable normal tissue protection. The benefits from 4D robust optimization were most obvious for the 2 typical stage III lung cancer patients. Conclusions: Our exploratory methodology study showed that, compared to 3D robust optimization, 4D robust optimization produced significantly more robust and interplay-effect-resistant plans for targets with comparable dose distributions for normal tissues. A further study with a larger and more realistic patient population is warranted to generalize the conclusions.« less

SU-E-T-618: Plan Robustness Study of Volumetric-Modulated Arc Therapy Vs. Intensity-Modulated Radiation Therapy for Head and Neck Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, W; Patel, S; Shen, J

Purpose: Lack of plan robustness may contribute to local failure in volumetric-modulated arc therapy (VMAT) to treat head and neck (H&N) cancer. Thus we compared plan robustness of VMAT with intensity-modulated radiation therapy (IMRT). Methods: VMAT and IMRT plans were created for 9 H&N cancer patients. For each plan, six new perturbed dose distributions were computed — one each for ± 3mm setup deviations along the S-I, A-P and L-R directions. We used three robustness quantification tools: (1) worst-case analysis (WCA); (2) dose-volume histograms (DVHs) band (DVHB); and (3) root-mean-square-dose deviation (RMSD) volume histogram (DDVH). DDVH represents the relative volumemore » (y) on the vertical axis and the RMSD (x) on the horizontal axis. Similar to DVH, this means that y% of the volume of the indicated structure has the RMSD at least x Gy[RBE].The width from the first two methods at different target DVH indices (such as D95 and D5) and the area under the DDVH curves (AUC) for the target were used to indicate plan robustness. In these robustness quantification tools, the smaller the value, the more robust the plan is. Plan robustness evaluation metrics were compared using Wilcoxon test. Results: DVHB showed the width at D95 from IMRT to be larger than from VMAT (unit Gy) [1.59 vs 1.18 (p=0.49)], while the width at D5 from IMRT was found to be slightly larger than from VMAT [0.59 vs 0.54 (p=0.84)]. WCA showed similar results [D95: 3.28 vs 3.00 (p=0.56); D5: 1.68 vs 1.95 (p=0.23)]. DDVH showed the AUC from IMRT to be slightly smaller than from VMAT [1.13 vs 1.15 (p=0.43)]. Conclusion: VMAT plan robustness is comparable to IMRT plan robustness. The plan robustness conclusions from WCA and DVHB are DVH parameter dependent. On the other hand DDVH captures the overall effect of uncertainties on the dose to a volume of interest. NIH/NCI K25CA168984; Eagles Cancer Research Career Development; The Lawrence W. and Marilyn W. Matteson Fund for Cancer Research Mayo ASU Seed Grant; The Kemper Marley Foundation.« less

Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data.

PubMed

Reisetter, Anna C; Muehlbauer, Michael J; Bain, James R; Nodzenski, Michael; Stevens, Robert D; Ilkayeva, Olga; Metzger, Boyd E; Newgard, Christopher B; Lowe, William L; Scholtens, Denise M

2017-02-02

Metabolomics offers a unique integrative perspective for health research, reflecting genetic and environmental contributions to disease-related phenotypes. Identifying robust associations in population-based or large-scale clinical studies demands large numbers of subjects and therefore sample batching for gas-chromatography/mass spectrometry (GC/MS) non-targeted assays. When run over weeks or months, technical noise due to batch and run-order threatens data interpretability. Application of existing normalization methods to metabolomics is challenged by unsatisfied modeling assumptions and, notably, failure to address batch-specific truncation of low abundance compounds. To curtail technical noise and make GC/MS metabolomics data amenable to analyses describing biologically relevant variability, we propose mixture model normalization (mixnorm) that accommodates truncated data and estimates per-metabolite batch and run-order effects using quality control samples. Mixnorm outperforms other approaches across many metrics, including improved correlation of non-targeted and targeted measurements and superior performance when metabolite detectability varies according to batch. For some metrics, particularly when truncation is less frequent for a metabolite, mean centering and median scaling demonstrate comparable performance to mixnorm. When quality control samples are systematically included in batches, mixnorm is uniquely suited to normalizing non-targeted GC/MS metabolomics data due to explicit accommodation of batch effects, run order and varying thresholds of detectability. Especially in large-scale studies, normalization is crucial for drawing accurate conclusions from non-targeted GC/MS metabolomics data.

Application of the Aqueous Porous Pathway Model to Quantify the Effect of Sodium Lauryl Sulfate on Ultrasound-Induced Skin Structural Perturbation

PubMed Central

Polat, Baris E.; Seto, Jennifer E.; Blankschtein, Daniel; Langer, Robert

2011-01-01

This study investigated the effect of sodium lauryl sulfate (SLS) on skin structural perturbation when utilized simultaneously with low-frequency sonophoresis (LFS). Pig full-thickness skin (FTS) and pig split-thickness skin (STS) treated with LFS/SLS and LFS were analyzed in the context of the aqueous porous pathway model to quantify skin perturbation through changes in skin pore radius and porosity-to-tortuosity ratio (ε/τ). In addition, skin treatment times required to attain specific levels of skin electrical resistivity were analyzed to draw conclusions about the effect of SLS on reproducibility and predictability of skin perturbation. We found that LFS/SLS-treated FTS, LFS/SLS-treated STS, and LFS-treated FTS exhibited similar skin perturbation. However, LFS-treated STS exhibited significantly higher skin perturbation, suggesting greater structural changes to the less robust STS induced by the purely physical enhancement mechanism of LFS. Evaluation of ε/τ values revealed that LFS/SLS-treated FTS and STS have similar transport pathways, while LFS-treated FTS and STS have lower ε/τ values. In addition, LFS/SLS treatment times were much shorter than LFS treatment times for both FTS and STS. Moreover, the simultaneous use of SLS and LFS not only results in synergistic enhancement, as reflected in the shorter skin treatment times, but also in more predictable and reproducible skin perturbation. PMID:20963845

Mobile interfaces: Liquids as a perfect structural material for multifunctional, antifouling surfaces

DOE PAGES

Grinthal, Alison; Aizenberg, Joanna

2013-10-14

Life creates some of its most robust, extreme surface materials not from solids but from liquids: a purely liquid interface, stabilized by underlying nanotexture, makes carnivorous plant leaves ultraslippery, the eye optically perfect and dirt-resistant, our knees lubricated and pressure-tolerant, and insect feet reversibly adhesive and shape-adaptive. Novel liquid surfaces based on this idea have recently been shown to display unprecedented omniphobic, self-healing, anti-ice, antifouling, optical, and adaptive properties. In this Perspective, we present a framework and a path forward for developing and designing such liquid surfaces into sophisticated, versatile multifunctional materials. Drawing on concepts from solid materials design andmore » fluid dynamics, we outline how the continuous dynamics, responsiveness, and multiscale patternability of a liquid surface layer can be harnessed to create a wide range of unique, active interfacial functions-able to operate in harsh, changing environments-not achievable with static solids. We discuss how, in partnership with the underlying substrate, the liquid surface can be programmed to adaptively and reversibly reconfigure from a defect-free, molecularly smooth, transparent interface through a range of finely tuned liquid topographies in response to environmental stimuli. In conclusion, with nearly unlimited design possibilities and unmatched interfacial properties, liquid materials-as long-term stable interfaces yet in their fully liquid state-may potentially transform surface design everywhere from medicine to architecture to energy infrastructure.« less

Modelling trading networks and the role of trust

NASA Astrophysics Data System (ADS)

Barrio, Rafael A.; Govezensky, Tzipe; Ruiz-Gutiérrez, Élfego; Kaski, Kimmo K.

2017-04-01

We present a simple dynamical model for describing trading interactions between agents in a social network by considering only two dynamical variables, namely money and goods or services, that are assumed conserved over the whole time span of the agents' trading transactions. A key feature of the model is that agent-to-agent transactions are governed by the price in units of money per goods, which is dynamically changing, and by a trust variable, which is related to the trading history of each agent. All agents are able to sell or buy, and the decision to do either has to do with the level of trust the buyer has in the seller, the price of the goods and the amount of money and goods at the disposal of the buyer. Here we show the results of extensive numerical calculations under various initial conditions in a random network of agents and compare the results with the available related data. In most cases the agreement between the model results and real data turns out to be fairly good, which allow us to draw some general conclusions as how different trading strategies could affect the distribution of wealth in different kinds of societies. Our calculations reveal the striking effects of trust in commercial relations, namely that trust makes trading links more robust and the wealth distribution more even as well as allows for the existence of a healthy middle class.

Accessing Secondary Markets as a Capital Source for Energy Efficiency Finance Programs: Program Design Considerations for Policymakers and Administrators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kramer, C.; Martin, E. Fadrhonc; Thompson, P.

Estimates of the total opportunity for investment in cost-effective energy efficiency in the United States are typically in the range of several hundred billion dollars (Choi Granade, et al., 2009 and Fulton & Brandenburg, 2012).1,2 To access this potential, many state policymakers and utility regulators have established aggressive energy efficiency savings targets. Current levels of taxpayer and utility bill-payer funding for energy efficiency is only a small fraction of the total investment needed to meet these targets (SEE Action Financing Solutions Working Group, 2013). Given this challenge, some energy efficiency program administrators are working to access private capital sources withmore » the aim of amplifying the funds available for investment. In this context, efficient access to secondary market capital has been advanced as one important enabler of the energy efficiency industry “at scale.”3 The question of what role secondary markets can play in bringing energy efficiency to scale is largely untested despite extensive attention from media, technical publications, advocates, and others. Only a handful of transactions of energy efficiency loan products have been executed to date, and it is too soon to draw robust conclusions from these deals. At the same time, energy efficiency program administrators and policymakers face very real decisions regarding whether and how to access secondary markets as part of their energy efficiency deployment strategy.« less

Electrophysiology reveals semantic priming at a short SOA irrespective of depth of prime processing.

PubMed

Küper, Kristina; Heil, Martin

2009-04-03

The otherwise robust behavioral semantic priming effect is reduced to the point of being absent when a letter search has to be performed on the prime word. As a result the automaticity of semantic activation has been called into question. It is unclear, however, in how far automatic processes are even measurable in the letter search priming paradigm as the prime task necessitates a long prime-probe stimulus-onset asynchrony (SOA). In a modified procedure, a short SOA can be realized by delaying the prime task response until after participants have made a lexical decision on the probe. While the absence of lexical decision priming has already been demonstrated in this design it seems premature to draw any definite conclusions from this purely behavioral result since event related potential (ERP) measures have been shown to be a more sensitive index of semantic activation. Using the modified paradigm we thus recorded ERP in addition to lexical decision times. Stimuli were presented at two different SOAs (240 ms vs. 840 ms) and participants performed either a grammatical discrimination (Experiment 1) or a letter search (Experiment 2) on the prime. Irrespective of prime task, the modulation of the N400, the ERP correlate of semantic activation, provided clear-cut evidence of semantic processing at the short SOA. Implications for theories of semantic activation as well as the constraints of the delayed prime task procedure are discussed.

Prospects of Silicon Photomultipliers for Ground-Based Cosmic Ray Experiments

NASA Astrophysics Data System (ADS)

Peters, Christine; Bretz, Thomas; Hebbeker, Thomas; Kemp, Julian; Lauscher, Markus; Middendorf, Lukas; Niggemann, Tim; Schumacher, Johannes

An established technique to study ultra-high-energy cosmic rays is the detection of extensive air showers induced in the atmosphere of the earth. Thereby, cascades of secondary particles are produced consisting of a hadronic, an electromagnetic and a muonic component. Especially the determination of the number of muons and the amount of fluorescence light produced during the shower development allows to draw conclusions on the mass and energy of the primary particle. Thus, these are important observables for air shower experiments like for instance the Pierre Auger Observatory in Argentina, and its AugerPrime upgrade in progress. The steady development of semiconductor devices in the last years resulted in highly improved photon sensors, e.g., silicon photomultipliers (SiPMs). The small package and moderate bias voltage (<100 V) of these silicon devices allow for compact and robust designs. Detailed detector simulations, the development of dedicated front-end electronics, as well as construction and investigation of detector prototypes, are needed to study the applicability of SiPMs for cosmic ray experiments. We present our findings for two different detector techniques: First, we present the fluorescence telescope, FAMOUS. Its basic principle is based on a Fresnel lens focusing the incoming light onto a camera instrumented with 61 pixels. Secondly, the benefit of the application of SiPMs is studied for scintillator detectors designed for an improved determination of the muonic component in air showers of current experiments.

Drawing Inspiration from Human Brain Networks: Construction of Interconnected Virtual Networks

PubMed Central

Kominami, Daichi; Leibnitz, Kenji; Murata, Masayuki

2018-01-01

Virtualization of wireless sensor networks (WSN) is widely considered as a foundational block of edge/fog computing, which is a key technology that can help realize next-generation Internet of things (IoT) networks. In such scenarios, multiple IoT devices and service modules will be virtually deployed and interconnected over the Internet. Moreover, application services are expected to be more sophisticated and complex, thereby increasing the number of modifications required for the construction of network topologies. Therefore, it is imperative to establish a method for constructing a virtualized WSN (VWSN) topology that achieves low latency on information transmission and high resilience against network failures, while keeping the topological construction cost low. In this study, we draw inspiration from inter-modular connectivity in human brain networks, which achieves high performance when dealing with large-scale networks composed of a large number of modules (i.e., regions) and nodes (i.e., neurons). We propose a method for assigning inter-modular links based on a connectivity model observed in the cerebral cortex of the brain, known as the exponential distance rule (EDR) model. We then choose endpoint nodes of these links by controlling inter-modular assortativity, which characterizes the topological connectivity of brain networks. We test our proposed methods using simulation experiments. The results show that the proposed method based on the EDR model can construct a VWSN topology with an optimal combination of communication efficiency, robustness, and construction cost. Regarding the selection of endpoint nodes for the inter-modular links, the results also show that high assortativity enhances the robustness and communication efficiency because of the existence of inter-modular links of two high-degree nodes. PMID:29642483

Drawing Inspiration from Human Brain Networks: Construction of Interconnected Virtual Networks.

PubMed

Murakami, Masaya; Kominami, Daichi; Leibnitz, Kenji; Murata, Masayuki

2018-04-08

Virtualization of wireless sensor networks (WSN) is widely considered as a foundational block of edge/fog computing, which is a key technology that can help realize next-generation Internet of things (IoT) networks. In such scenarios, multiple IoT devices and service modules will be virtually deployed and interconnected over the Internet. Moreover, application services are expected to be more sophisticated and complex, thereby increasing the number of modifications required for the construction of network topologies. Therefore, it is imperative to establish a method for constructing a virtualized WSN (VWSN) topology that achieves low latency on information transmission and high resilience against network failures, while keeping the topological construction cost low. In this study, we draw inspiration from inter-modular connectivity in human brain networks, which achieves high performance when dealing with large-scale networks composed of a large number of modules (i.e., regions) and nodes (i.e., neurons). We propose a method for assigning inter-modular links based on a connectivity model observed in the cerebral cortex of the brain, known as the exponential distance rule (EDR) model. We then choose endpoint nodes of these links by controlling inter-modular assortativity, which characterizes the topological connectivity of brain networks. We test our proposed methods using simulation experiments. The results show that the proposed method based on the EDR model can construct a VWSN topology with an optimal combination of communication efficiency, robustness, and construction cost. Regarding the selection of endpoint nodes for the inter-modular links, the results also show that high assortativity enhances the robustness and communication efficiency because of the existence of inter-modular links of two high-degree nodes.

What Do Differences Between Multi-voxel and Univariate Analysis Mean? How Subject-, Voxel-, and Trial-level Variance Impact fMRI Analysis

PubMed Central

Davis, Tyler; LaRocque, Karen F.; Mumford, Jeanette; Norman, Kenneth A.; Wagner, Anthony D.; Poldrack, Russell A.

2014-01-01

Multi-voxel pattern analysis (MVPA) has led to major changes in how fMRI data are analyzed and interpreted. Many studies now report both MVPA results and results from standard univariate voxel-wise analysis, often with the goal of drawing different conclusions from each. Because MVPA results can be sensitive to latent multidimensional representations and processes whereas univariate voxel-wise analysis cannot, one conclusion that is often drawn when MVPA and univariate results differ is that the activation patterns underlying MVPA results contain a multidimensional code. In the current study, we conducted simulations to formally test this assumption. Our findings reveal that MVPA tests are sensitive to the magnitude of voxel-level variability in the effect of a condition within subjects, even when the same linear relationship is coded in all voxels. We also find that MVPA is insensitive to subject-level variability in mean activation across an ROI, which is the primary variance component of interest in many standard univariate tests. Together, these results illustrate that differences between MVPA and univariate tests do not afford conclusions about the nature or dimensionality of the neural code. Instead, targeted tests of the informational content and/or dimensionality of activation patterns are critical for drawing strong conclusions about the representational codes that are indicated by significant MVPA results. PMID:24768930

Data, Model, Conclusions, Doing It Again.

ERIC Educational Resources Information Center

Molenaar, Ivo W.

1998-01-01

Explores the robustness of conclusions from a statistical model against variations in model choice with an illustration from G. Box and G. Tiao (1973). Suggests that simultaneous consideration of a class of models for the same data is sometimes superior to analyzing the data under one model and demonstrates advantages to Adaptive Bayesian…

Teachers' Practices of Inquiry When Teaching Investigations: A Case Study

ERIC Educational Resources Information Center

Dudu, Washington T.; Vhurumuku, Elaosi

2012-01-01

Teacher practices are essential for supporting learners in scientific inquiry practices of framing research questions, designing and conducting investigations, collecting data, and drawing conclusions. This study examines instructional practices of two Grade 11 Physical Science teachers engaged in teaching practical investigations. Data were…

Body Data

ERIC Educational Resources Information Center

Bombaugh, Ruth; Jefferys, Lynn

2006-01-01

In this article, the authors demonstrate how a simple math lab incorporating monthly height measurements can address multiple science and mathematics standards such as collecting, organizing, and describing data in context; drawing conclusions; and making hypotheses from these data. Although the yearlong math lab can be accomplished in either the…

Continuing Professional Education Delivery Systems.

ERIC Educational Resources Information Center

Weeks, James P.

This investigation of delivery systems for continuing professional education provides an overview of current operational delivery systems in continuing professional education, drawing on experience as found in the literature. Learning theories and conclusions are woven into the descriptive text. Delivery systems profiled in the paper include the…

Development from Grades V through XI of Children's Ability to Make Correct Causal Inferences.

ERIC Educational Resources Information Center

Chen, Benjamin; Tuddenham, Read D.

1979-01-01

Unless sensitized to avoid them, Ss (regardless of grade) tended to draw overly sweeping inferences, perhaps because of a need for closure. Older Ss, however, were more successful at suspending judgment when no definite conclusion was justified. (Author/DLS)

Solid Waste Reduction--A Hands-on Study.

ERIC Educational Resources Information Center

Wiessinger, Diane

1991-01-01

This lesson plan uses grocery shopping to demonstrate the importance of source reduction in the handling of solid waste problems. Students consider different priorities in shopping (convenience, packaging, and waste reduction) and draw conclusions about the relationship between packaging techniques and solid waste problems. (MCO)

Ironic Effects of Drawing Attention to Story Errors

PubMed Central

Eslick, Andrea N.; Fazio, Lisa K.; Marsh, Elizabeth J.

2014-01-01

Readers learn errors embedded in fictional stories and use them to answer later general knowledge questions (Marsh, Meade, & Roediger, 2003). Suggestibility is robust and occurs even when story errors contradict well-known facts. The current study evaluated whether suggestibility is linked to participants’ inability to judge story content as correct versus incorrect. Specifically, participants read stories containing correct and misleading information about the world; some information was familiar (making error discovery possible), while some was more obscure. To improve participants’ monitoring ability, we highlighted (in red font) a subset of story phrases requiring evaluation; readers no longer needed to find factual information. Rather, they simply needed to evaluate its correctness. Readers were more likely to answer questions with story errors if they were highlighted in red font, even if they contradicted well-known facts. Though highlighting to-be-evaluated information freed cognitive resources for monitoring, an ironic effect occurred: Drawing attention to specific errors increased rather than decreased later suggestibility. Failure to monitor for errors, not failure to identify the information requiring evaluation, leads to suggestibility. PMID:21294039

Diagnosis of the OCD Patients using Drawing Features of the Bender Gestalt Shapes

PubMed Central

Boostani, R.; Asadi, F.; Mohammadi, N.

2017-01-01

Background: Since psychological tests such as questionnaire or drawing tests are almost qualitative, their results carry a degree of uncertainty and sometimes subjectivity. The deficiency of all drawing tests is that the assessment is carried out after drawing the objects and lots of information such as pen angle, speed, curvature and pressure are missed through the test. In other words, the psychologists cannot assess their patients while running the tests. One of the famous drawing tests to measure the degree of Obsession Compulsion Disorder (OCD) is the Bender Gestalt, though its reliability is not promising. Objective: The main objective of this study is to make the Bender Gestalt test quantitative; therefore, an optical pen along with a digital tablet is utilized to preserve the key drawing features of OCD patients during the test. Materials and Methods: Among a large population of patients who referred to a special clinic of OCD, 50 under therapy subjects voluntarily took part in this study. In contrast, 50 subjects with no sign of OCD performed the test as a control group. This test contains 9 shapes and the participants were not constraint to draw the shapes in a certain interval of time; consequently, to classify the stream of feature vectors (samples through drawing) Hidden Markov Model (HMM) is employed and its flexibility increased by incorporating the fuzzy technique into its learning scheme. Results: Applying fuzzy HMM classifier to the data stream of subjects could classify two groups up to 95.2% accuracy, whereas the results by applying the standard HMM resulted in 94.5%. In addition, multi-layer perceptron (MLP), as a strong static classifier, is applied to the features and resulted in 86.6% accuracy. Conclusion: Applying the pair of T-test to the results implies a significant supremacy of the fuzzy HMM to the standard HMM and MLP classifiers. PMID:28462208

Using statistical models to explore ensemble uncertainty in climate impact studies: the example of air pollution in Europe

NASA Astrophysics Data System (ADS)

Lemaire, Vincent E. P.; Colette, Augustin; Menut, Laurent

2016-03-01

Because of its sensitivity to unfavorable weather patterns, air pollution is sensitive to climate change so that, in the future, a climate penalty could jeopardize the expected efficiency of air pollution mitigation measures. A common method to assess the impact of climate on air quality consists in implementing chemistry-transport models forced by climate projections. However, the computing cost of such methods requires optimizing ensemble exploration techniques. By using a training data set from a deterministic projection of climate and air quality over Europe, we identified the main meteorological drivers of air quality for eight regions in Europe and developed statistical models that could be used to predict air pollutant concentrations. The evolution of the key climate variables driving either particulate or gaseous pollution allows selecting the members of the EuroCordex ensemble of regional climate projections that should be used in priority for future air quality projections (CanESM2/RCA4; CNRM-CM5-LR/RCA4 and CSIRO-Mk3-6-0/RCA4 and MPI-ESM-LR/CCLM following the EuroCordex terminology). After having tested the validity of the statistical model in predictive mode, we can provide ranges of uncertainty attributed to the spread of the regional climate projection ensemble by the end of the century (2071-2100) for the RCP8.5. In the three regions where the statistical model of the impact of climate change on PM2.5 offers satisfactory performances, we find a climate benefit (a decrease of PM2.5 concentrations under future climate) of -1.08 (±0.21), -1.03 (±0.32), -0.83 (±0.14) µg m-3, for respectively Eastern Europe, Mid-Europe and Northern Italy. In the British-Irish Isles, Scandinavia, France, the Iberian Peninsula and the Mediterranean, the statistical model is not considered skillful enough to draw any conclusion for PM2.5. In Eastern Europe, France, the Iberian Peninsula, Mid-Europe and Northern Italy, the statistical model of the impact of climate change on ozone was considered satisfactory and it confirms the climate penalty bearing upon ozone of 10.51 (±3.06), 11.70 (±3.63), 11.53 (±1.55), 9.86 (±4.41), 4.82 (±1.79) µg m-3, respectively. In the British-Irish Isles, Scandinavia and the Mediterranean, the skill of the statistical model was not considered robust enough to draw any conclusion for ozone pollution.

SU-E-T-07: 4DCT Robust Optimization for Esophageal Cancer Using Intensity Modulated Proton Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liao, L; Department of Industrial Engineering, University of Houston, Houston, TX; Yu, J

2015-06-15

Purpose: To develop a 4DCT robust optimization method to reduce the dosimetric impact from respiratory motion in intensity modulated proton therapy (IMPT) for esophageal cancer. Methods: Four esophageal cancer patients were selected for this study. The different phases of CT from a set of 4DCT were incorporated into the worst-case dose distribution robust optimization algorithm. 4DCT robust treatment plans were designed and compared with the conventional non-robust plans. Result doses were calculated on the average and maximum inhale/exhale phases of 4DCT. Dose volume histogram (DVH) band graphic and ΔD95%, ΔD98%, ΔD5%, ΔD2% of CTV between different phases were used tomore » evaluate the robustness of the plans. Results: Compare to the IMPT plans optimized using conventional methods, the 4DCT robust IMPT plans can achieve the same quality in nominal cases, while yield a better robustness to breathing motion. The mean ΔD95%, ΔD98%, ΔD5% and ΔD2% of CTV are 6%, 3.2%, 0.9% and 1% for the robustly optimized plans vs. 16.2%, 11.8%, 1.6% and 3.3% from the conventional non-robust plans. Conclusion: A 4DCT robust optimization method was proposed for esophageal cancer using IMPT. We demonstrate that the 4DCT robust optimization can mitigate the dose deviation caused by the diaphragm motion.« less

Performing Inferential Statistics Prior to Data Collection

ERIC Educational Resources Information Center

Trafimow, David; MacDonald, Justin A.

2017-01-01

Typically, in education and psychology research, the investigator collects data and subsequently performs descriptive and inferential statistics. For example, a researcher might compute group means and use the null hypothesis significance testing procedure to draw conclusions about the populations from which the groups were drawn. We propose an…

Mystery Boxes: Helping Children Improve Their Reasoning

ERIC Educational Resources Information Center

Rule, Audrey C.

2007-01-01

This guest editorial describes ways teachers can use guessing games about an unknown item in a "mystery box" to help children improve their abilities to listen to others, recall information, ask purposeful questions, classify items by class, make inferences, synthesize information, and draw conclusions. The author presents information…

Conclusions, Reflections, and Prospects for Future Research, Policy, and Programming

ERIC Educational Resources Information Center

Clark-Kazak, Christina

2012-01-01

This concluding chapter draws together some of the key themes from the contributions and proposes some recommended areas for future research, policy, and programming. It highlights the artificiality of categorization processes related to both migration and childhood that independent child migrants encounter, and problematizes the…

Dahlbeck and Pure Ontology

ERIC Educational Resources Information Center

Mackenzie, Jim

2016-01-01

This article responds to Johan Dahlbeck's "Towards a pure ontology: Children's bodies and morality" ["Educational Philosophy and Theory," vol. 46 (1), 2014, pp. 8-23 (EJ1026561)]. His arguments from Nietzsche and Spinoza do not carry the weight he supposes, and the conclusions he draws from them about pedagogy would be…

Brain Stretchers Book 4--Advanced.

ERIC Educational Resources Information Center

Anderson, Carolyn

This book provides puzzles, games, and mathematical activities for students in elementary grades. Number concepts and arithmetic are common topics. These classic math, logic, and word-problem activities encourage students to become flexible, creative thinkers while teaching them to draw valid conclusions based on logic and evidence. Each activity…

Thinking big

NASA Astrophysics Data System (ADS)

Collins, Harry

2008-02-01

Physicists are often quick to discount social research based on qualitative techniques such as ethnography and "deep case studies" - where a researcher draws conclusions about a community based on immersion in the field - thinking that only quantitative research backed up by statistical analysis is sound. The balance is not so clear, however.

The Impact of Data Fragmentation on High-Throughput Clinical Phenotyping

ERIC Educational Resources Information Center

Wei, Weiqi

2012-01-01

Subject selection is essential and has become the rate-limiting step for harvesting knowledge to advance healthcare through clinical research. Present manual approaches inhibit researchers from conducting deep and broad studies and drawing confident conclusions. High-throughput clinical phenotyping (HTCP), a recently proposed approach, leverages…

Effects of Scaffolds and Scientific Reasoning Ability on Web-Based Scientific Inquiry

ERIC Educational Resources Information Center

Wu, Hui-Ling; Weng, Hsiao-Lan; She, Hsiao-Ching

2016-01-01

This study examined how background knowledge, scientific reasoning ability, and various scaffolding forms influenced students' science knowledge and scientific inquiry achievements. The students participated in an online scientific inquiry program involving such activities as generating scientific questions and drawing evidence-based conclusions,…

The Localized Corrosion of Aluminum Alloys - A Review.

DTIC Science & Technology

1983-07-01

will be typical rather than comprehensive . The purpose will be to draw from these reports certain well-founded, and well-accepted conclusions useful...established by Nilsen and Bardal (161) who measured the pitting potential, Ep, the protection potential, E4 and, Ecrit . , above which the sample

Freshly Squeezed? I Prefer Concentrated!

ERIC Educational Resources Information Center

Strachan, Amy

2015-01-01

We cannot expect every child to leave primary school with the aspiration of becoming a scientist. It is, however, achievable for children to move through their education seeing the implications of science in everything we do. Questioning, predicting, interpreting data, drawing conclusions, communicating evidence and evaluating procedures are all…

Personalized Multi-Student Improvement Based on Bayesian Cybernetics

ERIC Educational Resources Information Center

Kaburlasos, Vassilis G.; Marinagi, Catherine C.; Tsoukalas, Vassilis Th.

2008-01-01

This work presents innovative cybernetics (feedback) techniques based on Bayesian statistics for drawing questions from an Item Bank towards personalized multi-student improvement. A novel software tool, namely "Module for Adaptive Assessment of Students" (or, "MAAS" for short), implements the proposed (feedback) techniques. In conclusion, a pilot…

Diagnosing Portuguese Students' Misconceptions about the Mineral Concept

ERIC Educational Resources Information Center

Monteiro, Antonio; Nobrega, Clevio; Abrantes, Isabel; Gomes, Celeste

2012-01-01

Educational researchers and teachers are well aware that misconceptions--erroneous ideas that differ from the scientifically accepted ones--are very common amongst students. Daily experiences, creative and perceptive thinking and science textbooks give rise to students' misconceptions which lead them to draw erroneous conclusions that become…

Genie Inference Engine Rule Writer’s Guide.

DTIC Science & Technology

1987-08-01

33 APPENDIX D. Animal Bootstrap File.............................................................. 39...APPENDIX E. Sample Run of Animal Identification Expert System.......................... 43 APPENDIX F. Numeric Test Knowledge Base...and other data s.tructures stored in the knowledge base (KB), queries the user for input, and draws conclusions. Genie (GENeric Inference Engine) is

Making Sense of Data: Context Matters

ERIC Educational Resources Information Center

Lovett, Jennifer N.; Lee, Hollylynne S.

2016-01-01

To draw conclusions from data, we need to understand the context of the data and the measurement units. In 2007, Franklin and colleagues presented the "Guidelines for Assessment and Instruction in Statistics Education (GAISE) Report" to provide teachers with a framework to assist in developing students' investigation of statistical…

Effects of Cognitive Demand on Word Encoding in Adults Who Stutter

ERIC Educational Resources Information Center

Tsai, Pei-Tzu

2011-01-01

The etiology of persistent stuttering is unknown, but stuttering has been attributed to multiple potential factors, including difficulty in processing language-related information, but findings remain inconclusive regarding any "specific" linguistic deficit potentially causing stuttering. One particular challenge in drawing conclusions is the…

What do large scale studies of medication in schizophrenia add to our management strategies?

PubMed

Agius, Mark; Davis, Abigail; Gilhooley, Michael; Chapman, Shelley; Zaman, Rashid

2010-06-01

A number of large naturalistic trials have reported in recent years comparing second generation antipsychotic drugs with their predecessors. The conclusions they draw have rightly sparked much debate, but are these studies truly comparable? If not, which of them are most methodologically robust and are these the studies most suitable as a foundation for clinical care guidelines with a strong evidence base. We aimed to conduct a review of the current literature to establish the appropriateness of several recent major clinical studies being used as the basis for clinical guidelines. A literature search using the PUBMED database was carried out. Five major studies comparing antipsychotic efficacy were selected as possible candidates and subjected to further analysis. The studies were: * CUTLASS (Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia study); * CATIE (Clinical Antipsychotic Trials of Intervention Effectiveness study); * SOHO (Schizophrenia outpatients Health Outcomes study); * CAFE (Comparison of Atypicals in First Episode study); * EUFEST (European First Episode Schizophrenia Trial). The trials: * CAFE - the trial, although well randomised and blinded, uses discontinuation as a primary endpoint - this is hard to draw conclusions from: patients may discontinue due to side effects, due to lack of efficacy or with against medical advice for a multitude of reasons. As a secondary endpoint, the study does make use of a PANSS scoring system to measure efficacy, adding some weight to the conclusion that olanzapine, quetiaine and risperidone in early psychosis patients have equivalent efficacies. * CATIE - This trial was a comparative study, and so lacked a control arm and used discontinuation of medication an inverse measure of efficacy - an easily quantifiable event, but making for difficult interpretation. However most criticism has been directed at the unusually low (quitiapine, ziprasidone) and high (olanzapine and perphenazine) doses of drug used, which were reflected in their differing rates of efficacy. * CUtLASS This trial allows for less generalisation of its findings to the general population as it makes use a specific sub-population (those switching from one medication to another after a period of treatment). Also some patients were prescribed oral medications and some depot injections - making comparisons difficult due to possible differences in compliance. * EUFEST This trial makes use of discontinuation as an endpoint with the weaknesses we have described. Treatment of first episodes of psychosis is shown to be feasible, but it could not suggest if haloperidol or second generation drugs may be more efficacious. * SOHO - This trial hindered by the observational design of the study and small numbers reaching the primary end point (4%) caution should be exercised in the conclusion that olanzapine is superior to risperidone, quetiapine or typical antipsychotics. There is much information useful for clinical practice to be gathered from the results of these major studies, however, interpretation is hampered by both variations and weakness in study design. On balance it does appear that different antipsychotics possess differing efficacy, but also of relevance to the development of sound clinical guidelines is their differing side effects profile.

Memorisation methods in science education: tactics to improve the teaching and learning practice

NASA Astrophysics Data System (ADS)

Pals, Frits F. B.; Tolboom, Jos L. J.; Suhre, Cor J. M.; van Geert, Paul L. C.

2018-01-01

How can science teachers support students in developing an appropriate declarative knowledge base for solving problems? This article focuses on the question whether the development of students' memory of scientific propositions is better served by writing propositions down on paper or by making drawings of propositions either by silent or muttering rehearsal. By means of a memorisation experiment with eighth- and ninth-grade students, we answer this question. In this experiment, students received instruction to memorise nine science propositions and to reproduce them afterwards. To support memorisation students were randomly assigned either to a group that received instruction to write each proposition on paper or to a group that received instruction to make a drawing about the content of the proposition. In addition, half of the students in both groups received instruction to mutter and the other half of them received instruction to write or draw in silence. The main conclusion from the experiment is that after four weeks students who had made a drawing remembered significantly more propositions than those who had memorised the propositions by writing them down. Our research further revealed that it did not matter whether students muttered or memorised silently.

Applying robust design to study the effects of stratigraphic characteristics on brittle failure and bump potential in a coal mine

PubMed Central

Kim, Bo-Hyun; Larson, Mark K.; Lawson, Heather E.

2018-01-01

Bumps and other types of dynamic failure have been a persistent, worldwide problem in the underground coal mining industry, spanning decades. For example, in just five states in the U.S. from 1983 to 2014, there were 388 reportable bumps. Despite significant advances in mine design tools and mining practices, these events continue to occur. Many conditions have been associated with bump potential, such as the presence of stiff units in the local geology. The effect of a stiff sandstone unit on the potential for coal bumps depends on the location of the stiff unit in the stratigraphic column, the relative stiffness and strength of other structural members, and stress concentrations caused by mining. This study describes the results of a robust design to consider the impact of different lithologic risk factors impacting dynamic failure risk. Because the inherent variability of stratigraphic characteristics in sedimentary formations, such as thickness, engineering material properties, and location, is significant and the number of influential parameters in determining a parametric study is large, it is impractical to consider every simulation case by varying each parameter individually. Therefore, to save time and honor the statistical distributions of the parameters, it is necessary to develop a robust design to collect sufficient sample data and develop a statistical analysis method to draw accurate conclusions from the collected data. In this study, orthogonal arrays, which were developed using the robust design, are used to define the combination of the (a) thickness of a stiff sandstone inserted on the top and bottom of a coal seam in a massive shale mine roof and floor, (b) location of the stiff sandstone inserted on the top and bottom of the coal seam, and (c) material properties of the stiff sandstone and contacts as interfaces using the 3-dimensional numerical model, FLAC3D. After completion of the numerical experiments, statistical and multivariate analysis are performed using the calculated results from the orthogonal arrays to analyze the effect of these variables. As a consequence, the impact of each of the parameters on the potential for bumps is quantitatively classified in terms of a normalized intensity of plastic dissipated energy. By multiple regression, the intensity of plastic dissipated energy and migration of the risk from the roof to the floor via the pillars is predicted based on the value of the variables. The results demonstrate and suggest a possible capability to predict the bump potential in a given rock mass adjacent to the underground excavations and pillars. Assessing the risk of bumps is important to preventing fatalities and injuries resulting from bumps. PMID:29416902

Games for learning: vast wasteland or a digital promise?

PubMed

Levine, Michael H; Vaala, Sarah E

2013-01-01

Research about emerging best practices in the learning sciences points to the potential of deploying digital games as one possible solution to the twin challenges of weak student engagement and the need for more robust achievement in literacy, science, technology, and math. This chapter reviews key cross-cutting themes in this special volume, drawing perspective from the context of the current United States program and policy reform. The authors conclude that digital games have some unique potential to address pressing educational challenges, but that new mechanisms for advancing purposeful research and development must be adopted by both policymakers and industry leaders. Copyright © 2013 Wiley Periodicals, Inc., A Wiley Company.

The road less taken: modularization and waterways as a domestic disaster response mechanism.

PubMed

Donahue, Donald A; Cunnion, Stephen O; Godwin, Evelyn A

2013-01-01

Preparedness scenarios project the need for significant healthcare surge capacity. Current planning draws heavily from the military model, leveraging deployable infrastructure to augment or replace extant capabilities. This approach would likely prove inadequate in a catastrophic disaster, as the military model relies on forewarning and an extended deployment cycle. Local equipping for surge capacity is prohibitively costly while movement of equipment can be subject to a single point of failure. Translational application of maritime logistical techniques and an ancient mode of transportation can provide a robust and customizable approach to disaster relief for greater than 90 percent of the American population.

Modified harmony search

NASA Astrophysics Data System (ADS)

Mohamed, Najihah; Lutfi Amri Ramli, Ahmad; Majid, Ahmad Abd; Piah, Abd Rahni Mt

2017-09-01

A metaheuristic algorithm, called Harmony Search is quite highly applied in optimizing parameters in many areas. HS is a derivative-free real parameter optimization algorithm, and draws an inspiration from the musical improvisation process of searching for a perfect state of harmony. Propose in this paper Modified Harmony Search for solving optimization problems, which employs a concept from genetic algorithm method and particle swarm optimization for generating new solution vectors that enhances the performance of HS algorithm. The performances of MHS and HS are investigated on ten benchmark optimization problems in order to make a comparison to reflect the efficiency of the MHS in terms of final accuracy, convergence speed and robustness.

A critique of Lilienfeld et al.'s (2000) "The scientific status of projective techniques".

PubMed

Hibbard, Stephen

2003-06-01

Lilienfeld, Wood, and Garb (2000) published a largely negative critique of the validity and reliability of projective methods, concentrating on the Comprehensive System for the Rorschach (Exner, 1993), 3 systems for coding the Thematic Apperception Test (TAT; Murray, 1943) cards, and human figure drawings. This article is an effort to document and correct what I perceive as errors of omission and commission in the Lilienfeld et al. article. When projective measures are viewed in the light of these corrections, the evidence for the validity and clinical usefulness of the Rorschach and TAT methods is more robust than Lilienfeld et al. represented.

Learning the 3-D structure of objects from 2-D views depends on shape, not format

PubMed Central

Tian, Moqian; Yamins, Daniel; Grill-Spector, Kalanit

2016-01-01

Humans can learn to recognize new objects just from observing example views. However, it is unknown what structural information enables this learning. To address this question, we manipulated the amount of structural information given to subjects during unsupervised learning by varying the format of the trained views. We then tested how format affected participants' ability to discriminate similar objects across views that were rotated 90° apart. We found that, after training, participants' performance increased and generalized to new views in the same format. Surprisingly, the improvement was similar across line drawings, shape from shading, and shape from shading + stereo even though the latter two formats provide richer depth information compared to line drawings. In contrast, participants' improvement was significantly lower when training used silhouettes, suggesting that silhouettes do not have enough information to generate a robust 3-D structure. To test whether the learned object representations were format-specific or format-invariant, we examined if learning novel objects from example views transfers across formats. We found that learning objects from example line drawings transferred to shape from shading and vice versa. These results have important implications for theories of object recognition because they suggest that (a) learning the 3-D structure of objects does not require rich structural cues during training as long as shape information of internal and external features is provided and (b) learning generates shape-based object representations independent of the training format. PMID:27153196

Creative Soil Conservation

ERIC Educational Resources Information Center

Smith, Martha

2010-01-01

Take plant lessons outdoors with this engaging and inquiry-based activity in which third-grade students learn how to apply soil conservation methods to growing plants. They also collect data and draw conclusions about the effectiveness of their method of soil conservation. An added benefit to this activity is that the third-grade students played…

A Systematic Review of Depression Treatments in Primary Care for Latino Adults

ERIC Educational Resources Information Center

Cabassa, Leopoldo J.; Hansen, Marissa C.

2007-01-01

Objective: A systematic literature review of randomized clinical trials (RCTs) assessing depression treatments in primary care for Latinos is conducted. The authors rate the methodological quality of studies, examine cultural and linguistic adaptations, summarize clinical outcomes and cost-effectiveness findings, and draw conclusions for improving…

Secrets of a Mass Grave

ERIC Educational Resources Information Center

Ament, Caitlin Marie; Graham, Theodore J.

2017-01-01

This article presents a unit of study in which students examine skeletons and draw conclusions from the evidence they find in a simulated mass grave. The activity involves the foundation of forensic anthropology--interpreting the structure of skeletal remains to determine sex, age, height, and possible cause of death. Working through a series of…

Seat Belts in School Buses: A Technical Analysis of the Literature.

ERIC Educational Resources Information Center

Splaine, Pam; Frankel, Steven M.

This report, prepared for the Montgomery County (Maryland) Public Schools superintendent and board members, identifies the questions concerning seat belt use in school buses, examines relevant literature, and draws some conclusions. According to the literature, seat belts are one of many alternative and interdependent safety devices built into…

The Law School as a Base for Interdisciplinary Studies in a University

ERIC Educational Resources Information Center

Willrich, Mason

1974-01-01

Discusses the objectives of the Center for the Study of Science, Technology and Public Policy at the School of Law of the University of Virginia, summarizes the center's activities, and draws conclusions concerning the future role of a problem-oriented, interdisciplinary study in legal education. (Author/PG)

Brief Report: Immune Factors in Autism: A Critical Review.

ERIC Educational Resources Information Center

Krause, Ilan; He, Ziao-Song; Gershwin, M. Eric; Shoenfeld, Yehuda

2002-01-01

This article reviews studies linking autistic disorder with various immune factors. It concludes that although various immune system abnormalities have been reported in children with autism, previous studies are largely association based and it remains difficult to draw conclusions regarding the role of immune factors in the etiopathogenesis of…

Iconic Memory

ERIC Educational Resources Information Center

Sakitt, Barbara

1976-01-01

Describes a series of experiments showing that in normal subjects (a) iconic storage occurs primarily in the retina in the photoreceptors and (b) under conditions of dark pre- and postexposure fields, the icon is mainly a rod phenomenon. Draws conclusions based on these experiments, discusses previous work done by others, and attempts to reconcile…

ETV Programmes: Review of Research.

ERIC Educational Resources Information Center

Chaudhary, Sohanvir; Panda, Santosh

1997-01-01

Reviews research on educational television (ETV), focusing on teacher and student attitudes; impact on children and teachers and in-service education in media; and utilization. Also reviews a few studies on the impact and utilization of educational radio broadcasts. Draws broad conclusions about the use, design, and learning process of ETV. (PEN)

Connectivity and Resilience: A Multidimensional Analysis of Infrastructure Impacts in the Southwestern Amazon

ERIC Educational Resources Information Center

Perz, Stephen G.; Shenkin, Alexander; Barnes, Grenville; Cabrera, Liliana; Carvalho, Lucas A.; Castillo, Jorge

2012-01-01

Infrastructure is a worldwide policy priority for national development via regional integration into the global economy. However, economic, ecological and social research draws contrasting conclusions about the consequences of infrastructure. We present a synthetic approach to the study of infrastructure, focusing on a multidimensional treatment…

(Ig)Noble Lies: Personal Historicism and Richard Mulcaster's "Positions Concerning the Bringing up of Children" (1581)

ERIC Educational Resources Information Center

De Barros, Eric

2013-01-01

Attempting to push early modern presentism to the radical, logical conclusion of a more personal historicism, this essay draws on a number of interpretive practices and theoretical insights--Stephen Greenblatt's self-reflectivity, Toni Morrison's "rememory," Marianne Hirsch's "postmemory," bell hooks's "passion of…

Identifying Country-Specific Cultures of Physics Education: A Differential Item Functioning Approach

ERIC Educational Resources Information Center

Mesic, Vanes

2012-01-01

In international large-scale assessments of educational outcomes, student achievement is often represented by unidimensional constructs. This approach allows for drawing general conclusions about country rankings with respect to the given achievement measure, but it typically does not provide specific diagnostic information which is necessary for…

To House the Migrant.

ERIC Educational Resources Information Center

Miller, Paul F.

Commissioned by the New York State Center for Migrant Studies to develop a report on improvement in the living environment of migrant workers during their sojourn within New York State, the author draws his conclusions from such information sources as interviews with migrants, growers, and state and national officials; personal labor camp visits;…

Data Interpretation: Using Probability

ERIC Educational Resources Information Center

Drummond, Gordon B.; Vowler, Sarah L.

2011-01-01

Experimental data are analysed statistically to allow researchers to draw conclusions from a limited set of measurements. The hard fact is that researchers can never be certain that measurements from a sample will exactly reflect the properties of the entire group of possible candidates available to be studied (although using a sample is often the…

Out of the Stone Age

ERIC Educational Resources Information Center

Kademan, Robyn

2005-01-01

One of the most beneficial uses for technology in the science classroom is data manipulation. During labs and other learning experiences, students can quickly put the data they collect into spreadsheets or databases. Then they can make comparisons, create graphs, draw conclusions, sort the data in new ways, and, ultimately, give their data…

75 FR 13745 - Office of Innovation and Improvement Overview Information; Ready To Teach Program-General...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

... on rigorous, scientifically based research methods to assess the effectiveness of a particular... and programs; and (B) Includes research that-- (i) Employs systematic, empirical methods that draw on... hypotheses and justify the general conclusions drawn; (iii) Relies on measurements or observational methods...

Do State Examinations Measure Teacher Quality?

ERIC Educational Resources Information Center

Harrell, Pamela Esprivalo

2009-01-01

This study investigates teacher content knowledge of candidates enrolled in an online graduate teacher certification programme. Descriptive data and linear regression were used to draw conclusions about the content area knowledge of individuals in the sample and the significance of the predictors examined. Descriptive data show 1/3 of the 8-12…

Extending Engineering Practice Research with Shared Qualitative Data

ERIC Educational Resources Information Center

Trevelyan, James

2016-01-01

Research on engineering practice is scarce and sharing of qualitative research data can reduce the effort required for an aspiring researcher to obtain enough data from engineering workplaces to draw generalizable conclusions, both qualitative and quantitative. This paper describes how a large shareable qualitative data set on engineering…

Supporting the M-Learning Based Knowledge Transfer in University Education and Corporate Sector

ERIC Educational Resources Information Center

Benedek, András; Molnár, György

2014-01-01

The evolution of today's connective forms of teaching and learning draws attention to expansion of "space" in which teaching and learning moments: engaging the attention, knowledge transfer, acquisition, demonstration, experience, experiment research and practice, conclusions are organized around a more free method. Due to these…

Overview of hemlock health

Treesearch

Dennis R. Souto; Kathleen S. Shields

2000-01-01

Although many insects and diseases are associated with hemlock, we will, ironically, draw our first conclusion, that hemlocks are very sensitive to the stress of insect defoliation, from a tale of gypsy moth defoliation. The unprecedented gypsy moth (Lymantria dispar L.) outbreak of 1981, when nearly 13 million acres were defoliated in the Northeast...

Designing a Master Program in Educational Leadership: Trends, Reflections, and Conclusions.

ERIC Educational Resources Information Center

Aitken, Art; Bedard, George; Darroch, Amber

This paper presents a dialogue about the current context for educational leadership preparation that draws upon worldwide thought and discussion on the issue. Topics considered include recognition by faculty at the University of Lethbridge that educational leadership has problems in content alignment, relevance, and pedagogy. Research shows that…

Crashing the Language Barrier! The English Language: The Way It Is.

ERIC Educational Resources Information Center

Murray, Dorothy S.

Intended for adults in search of improved language skills and their leaders, this handbook provides opportunities to strengthen abilities to listen, observe, organize, solve problems, evaluate, and draw tentative conclusions about the English language. The handbook contains a proposition about the English language, suggests procedures to confirm…

Design and Implementation Considerations for Alternative Teacher Compensation Programs

ERIC Educational Resources Information Center

Brodsky, Andrew; DeCesare, Dale; Kramer-Wine, Jennifer

2010-01-01

Over the past decade, educators and policymakers have used a variety of approaches to designing and implementing teacher compensation programs. These approaches include federal incentive funds, state-level programs, and district initiatives. This article reviews 6 such programs in order to identify themes and draw conclusions relevant to…

The Emotional Life of the Toddler.

ERIC Educational Resources Information Center

Lieberman, Alicia F.

Noting that parenting a toddler can be both exhilarating and frustrating, this book draws on lifelong research into children's emotional development to provide parents with a better understanding of toddlers' emotional range and how it affects toddler behavior. The 10 chapters and the conclusion cover the following areas: (1) the emotional…

Online Learners and Their Learning Strategies.

ERIC Educational Resources Information Center

Dewar, Tammy; Whittington, Dave

2000-01-01

Describes an experiment that looked at how adult learners made use of their Myers-Briggs Type Indicator (MBTI[R]), a personality assessment tool, type to cope with the challenges of learning in an online environment. Presents results of the experiment, and draws tentative conclusions. Provides notes related to the four psychological dimensions of…

An effective and efficient assessment process

Treesearch

Russell T. Graham; Theresa B. Jain

1999-01-01

Depending on the agency, discipline, or audience, assessments supply data and information to address relevant policy questions and to help make decisions. If properly executed, assessment processes can draw conclusions and make recommendations on how to manage natural resources. Assessments, especially large ones, can be easily influenced by internal and external...

Perceptions of Undergraduate Graphic Design Students on the Educational Potential of Facebook

ERIC Educational Resources Information Center

Souleles, Nicos

2012-01-01

The popularity of Facebook among university students inevitably raises questions on the educational potential of this Social Networking Site for Higher Education. From the limited literature on the instructional uses of Facebook, one can draw conflicting conclusions. Benefits were identified through the communicative potential, student…

World Wide Web Homepage Design.

ERIC Educational Resources Information Center

Tillman, Michael L.

This paper examines hypermedia design and draws conclusions about how educational research and theory applies to various aspects of World Wide Web (WWW) homepage design. "Hypermedia" is defined as any collection of information which may be textual, graphical, visual, or auditory in nature and which may be accessed via a nonlinear route.…

Affirmative Action: Opportunity or Obstacle.

ERIC Educational Resources Information Center

Altman, Ellen; Promis, Patricia

Data about managerial positions and applicants were collected in an attempt to draw conclusions about the extent to which gender and ethnicity relate to the outcomes of the search and screen process for middle and senior management positions in academic libraries, and to determine any effects of affirmative action on promotion from within.…

Win, Lose, and Drawing Conclusions: Bellows, Boxing, and Progressivism.

ERIC Educational Resources Information Center

Adams, Peter A.

1992-01-01

Presents a lesson plan in which George Bellows's painting "Both Members of this Club" is analyzed as a historical document illustrating the Progressive movement. Suggests that the lesson can introduce students to a different form of historical communication. Includes background information and procedures for approaching the lesson.…

Errors of Inference in Structural Equation Modeling

ERIC Educational Resources Information Center

McCoach, D. Betsy; Black, Anne C.; O'Connell, Ann A.

2007-01-01

Although structural equation modeling (SEM) is one of the most comprehensive and flexible approaches to data analysis currently available, it is nonetheless prone to researcher misuse and misconceptions. This article offers a brief overview of the unique capabilities of SEM and discusses common sources of user error in drawing conclusions from…

Harvard Education Letter. Volume 27, Number 1, January-February 2011

ERIC Educational Resources Information Center

Walser, Caroline T., Ed.

2011-01-01

"Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) The Greening of Environmental Ed: Teachers Focus on Complexity, Evidence, and Letting Students Draw Their Own Conclusions (Lucy Hood); (2) Like Teacher,…

Sciencewise: Discovering Scientific Process through Problem Solving. Book 2.

ERIC Educational Resources Information Center

Holley, Dennis

This book of activities uses problem solving to help students develop the basic science process skills of observing, predicting, designing/experimenting, eliminating, and drawing conclusions. The activities are divided into two sections: Dynamo Demos and Creative Challenges. The teacher-led Dynamo Demos help students to develop science process…

Sciencewise: Discovering Scientific Process through Problem Solving. Book 1.

ERIC Educational Resources Information Center

Holley, Dennis

This book of activities uses problem solving to help students develop the basic science process skills of observing, predicting, designing/experimenting, eliminating, and drawing conclusions. The activities are divided into two sections: Dynamo Demos and Creative Challenges. The teacher-led Dynamo Demos help students to develop science process…

Basic Inferences of Scientific Reasoning, Argumentation, and Discovery

ERIC Educational Resources Information Center

Lawson, Anton E.

2010-01-01

Helping students better understand how scientists reason and argue to draw scientific conclusions has long been viewed as a critical component of scientific literacy, thus remains a central goal of science instruction. However, differences of opinion persist regarding the nature of scientific reasoning, argumentation, and discovery. Accordingly,…

Judicial Review of Arbitration Awards in the Educational Sector.

ERIC Educational Resources Information Center

McKinney, Joseph R.; Place, A. William

1993-01-01

Reviews the grievance-arbitration process and examines the judiciary's approach to handling appeals of arbitrators' awards. Analyzes 213 court decisions made during a 10-year period involving appeals of arbitrators' awards. Draws some conclusions and further examines the relationship of the grievance-arbitration appeals process to public education…

Molecular mechanisms governing differential robustness of development and environmental responses in plants

PubMed Central

Lachowiec, Jennifer; Queitsch, Christine; Kliebenstein, Daniel J.

2016-01-01

Background Robustness to genetic and environmental perturbation is a salient feature of multicellular organisms. Loss of developmental robustness can lead to severe phenotypic defects and fitness loss. However, perfect robustness, i.e. no variation at all, is evolutionarily unfit as organisms must be able to change phenotype to properly respond to changing environments and biotic challenges. Plasticity is the ability to adjust phenotypes predictably in response to specific environmental stimuli, which can be considered a transient shift allowing an organism to move from one robust phenotypic state to another. Plants, as sessile organisms that undergo continuous development, are particularly dependent on an exquisite fine-tuning of the processes that balance robustness and plasticity to maximize fitness. Scope and Conclusions This paper reviews recently identified mechanisms, both systems-level and molecular, that modulate robustness, and discusses their implications for the optimization of plant fitness. Robustness in living systems arises from the structure of genetic networks, the specific molecular functions of the underlying genes, and their interactions. This very same network responsible for the robustness of specific developmental states also has to be built such that it enables plastic yet robust shifts in response to environmental changes. In plants, the interactions and functions of signal transduction pathways activated by phytohormones and the tendency for plants to tolerate whole-genome duplications, tandem gene duplication and hybridization are emerging as major regulators of robustness in development. Despite their obvious implications for plant evolution and plant breeding, the mechanistic underpinnings by which plants modulate precise levels of robustness, plasticity and evolvability in networks controlling different phenotypes are under-studied. PMID:26473020

On the contributions of topological features to transcriptional regulatory network robustness

PubMed Central

2012-01-01

Background Because biological networks exhibit a high-degree of robustness, a systemic understanding of their architecture and function requires an appraisal of the network design principles that confer robustness. In this project, we conduct a computational study of the contribution of three degree-based topological properties (transcription factor-target ratio, degree distribution, cross-talk suppression) and their combinations on the robustness of transcriptional regulatory networks. We seek to quantify the relative degree of robustness conferred by each property (and combination) and also to determine the extent to which these properties alone can explain the robustness observed in transcriptional networks. Results To study individual properties and their combinations, we generated synthetic, random networks that retained one or more of the three properties with values derived from either the yeast or E. coli gene regulatory networks. Robustness of these networks were estimated through simulation. Our results indicate that the combination of the three properties we considered explains the majority of the structural robustness observed in the real transcriptional networks. Surprisingly, scale-free degree distribution is, overall, a minor contributor to robustness. Instead, most robustness is gained through topological features that limit the complexity of the overall network and increase the transcription factor subnetwork sparsity. Conclusions Our work demonstrates that (i) different types of robustness are implemented by different topological aspects of the network and (ii) size and sparsity of the transcription factor subnetwork play an important role for robustness induction. Our results are conserved across yeast and E Coli, which suggests that the design principles examined are present within an array of living systems. PMID:23194062

A robust method for estimating motorbike count based on visual information learning

NASA Astrophysics Data System (ADS)

Huynh, Kien C.; Thai, Dung N.; Le, Sach T.; Thoai, Nam; Hamamoto, Kazuhiko

2015-03-01

Estimating the number of vehicles in traffic videos is an important and challenging task in traffic surveillance, especially with a high level of occlusions between vehicles, e.g.,in crowded urban area with people and/or motorbikes. In such the condition, the problem of separating individual vehicles from foreground silhouettes often requires complicated computation [1][2][3]. Thus, the counting problem is gradually shifted into drawing statistical inferences of target objects density from their shape [4], local features [5], etc. Those researches indicate a correlation between local features and the number of target objects. However, they are inadequate to construct an accurate model for vehicles density estimation. In this paper, we present a reliable method that is robust to illumination changes and partial affine transformations. It can achieve high accuracy in case of occlusions. Firstly, local features are extracted from images of the scene using Speed-Up Robust Features (SURF) method. For each image, a global feature vector is computed using a Bag-of-Words model which is constructed from the local features above. Finally, a mapping between the extracted global feature vectors and their labels (the number of motorbikes) is learned. That mapping provides us a strong prediction model for estimating the number of motorbikes in new images. The experimental results show that our proposed method can achieve a better accuracy in comparison to others.

Potentials for the use of tool-integrated in-line data acquisition systems in press shops

NASA Astrophysics Data System (ADS)

Maier, S.; Schmerbeck, T.; Liebig, A.; Kautz, T.; Volk, W.

2017-09-01

Robust in-line data acquisition systems are required for the realization of process monitoring and control systems in press shops. A promising approach is the integration of sensors in the following press tools. There they can be easy integrated and maintained. It also achieves the necessary robustness for the rough press environment. Such concepts were already investigated for the measurement of the geometrical accuracy as well as for the material flow of inner part areas. They enable the monitoring of each produced part’s quality. An important success factor are practical approaches to the use of this new process information in press shops. This work presents various applications of these measuring concepts, based on real car body components of the BMW Group. For example, the procedure of retroactive error analysis is explained for a side frame. It also shows how this data acquisition can be used for the optimization of drawing tools in tool shops. With the skid-line, there is a continuous value that can be monitored from planning to serial production.

Anodal transcranial direct current stimulation to the cerebellum improves handwriting and cyclic drawing kinematics in focal hand dystonia.

PubMed

Bradnam, Lynley V; Graetz, Lynton J; McDonnell, Michelle N; Ridding, Michael C

2015-01-01

There is increasing evidence that the cerebellum has a role in the pathophysiology of primary focal hand dystonia and might provide an intervention target for non-invasive brain stimulation to improve function of the affected hand. The primary objective of this study was to determine if cerebellar transcranial direct current stimulation (tDCS) improves handwriting and cyclic drawing kinematics in people with hand dystonia, by reducing cerebellar-brain inhibition (CBI) evoked by transcranial magnetic stimulation (TMS). Eight people with dystonia (5 writer's dystonia, 3 musician's dystonia) and eight age-matched controls completed the study and underwent cerebellar anodal, cathodal and sham tDCS in separate sessions. Dystonia severity was assessed using the Writer's Cramp Rating Scale (WRCS) and the Arm Dystonia Disability Scale (ADDS). The kinematic measures that differentiated the groups were; mean stroke frequency during handwriting and fast cyclic drawing and average pen pressure during light cyclic drawing. TMS measures of cortical excitability were no different between people with FHD and controls. There was a moderate, negative relationship between TMS-evoked CBI at baseline and the WRCS in dystonia. Anodal cerebellar tDCS reduced handwriting mean stroke frequency and average pen pressure, and increased speed and reduced pen pressure during fast cyclic drawing. Kinematic measures were not associated with a decrease in CBI within an individual. In conclusion, cerebellar anodal tDCS appeared to improve kinematics of handwriting and circle drawing tasks; but the underlying neurophysiological mechanism remains uncertain. A study in a larger homogeneous population is needed to further investigate the possible therapeutic benefit of cerebellar tDCS in dystonia.

Anodal transcranial direct current stimulation to the cerebellum improves handwriting and cyclic drawing kinematics in focal hand dystonia

PubMed Central

Bradnam, Lynley V.; Graetz, Lynton J.; McDonnell, Michelle N.; Ridding, Michael C.

2015-01-01

There is increasing evidence that the cerebellum has a role in the pathophysiology of primary focal hand dystonia and might provide an intervention target for non-invasive brain stimulation to improve function of the affected hand. The primary objective of this study was to determine if cerebellar transcranial direct current stimulation (tDCS) improves handwriting and cyclic drawing kinematics in people with hand dystonia, by reducing cerebellar-brain inhibition (CBI) evoked by transcranial magnetic stimulation (TMS). Eight people with dystonia (5 writer’s dystonia, 3 musician’s dystonia) and eight age-matched controls completed the study and underwent cerebellar anodal, cathodal and sham tDCS in separate sessions. Dystonia severity was assessed using the Writer’s Cramp Rating Scale (WRCS) and the Arm Dystonia Disability Scale (ADDS). The kinematic measures that differentiated the groups were; mean stroke frequency during handwriting and fast cyclic drawing and average pen pressure during light cyclic drawing. TMS measures of cortical excitability were no different between people with FHD and controls. There was a moderate, negative relationship between TMS-evoked CBI at baseline and the WRCS in dystonia. Anodal cerebellar tDCS reduced handwriting mean stroke frequency and average pen pressure, and increased speed and reduced pen pressure during fast cyclic drawing. Kinematic measures were not associated with a decrease in CBI within an individual. In conclusion, cerebellar anodal tDCS appeared to improve kinematics of handwriting and circle drawing tasks; but the underlying neurophysiological mechanism remains uncertain. A study in a larger homogeneous population is needed to further investigate the possible therapeutic benefit of cerebellar tDCS in dystonia. PMID:26042019

Kinematic and Pressure Features of Handwriting and Drawing: Preliminary Results Between Patients with Mild Cognitive Impairment, Alzheimer Disease and Healthy Controls

PubMed Central

Garre-Olmo, Josep; Faúndez-Zanuy, Marcos; López-de-Ipiña, Karmele; Calvó-Perxas, Laia; Turró-Garriga, Oriol

2017-01-01

Background: Alzheimer’s disease (AD) is the most common neurodegenerative dementia of old age, and the leading chronic disease contributor to disability and dependence among older people worldwide. Clinically, AD is characterized by a progressive cognitive decline that interferes with the abil-ity to perform the activities of daily living. Handwriting and drawing are complex human activities that entail an intricate blend of cognitive, kinesthetic, and perceptual-motor features. Objective: To compare the kinematic characteristics of handwriting and drawing between patients with AD, patients with mild cognitive impairment (MCI) and healthy controls. Methods: We used a cross-sectional and observational design to assess the kinematic and pressure fea-tures of handwriting and drawing using a computerized system. Participants were asked to copy one sen-tence, write a dictated sentence and an own sentence, copy two and-three dimensions drawings, and to execute the clock drawing test. By means of discriminant analyses, we explored the value of several kin-ematic features in order to classify participants depending on their degree of cognitive functioning. Results: The sample consisted of 52 participants (23 AD, 12 MCI, and 17 healthy controls) with a mean age of 69.7 years (SD=8.11). The degree of correct classification was largely dependent on the nature of the groups to be classified and the specific task, and ranged between 63.5% and 100%. Diagnostic accu-racy based on kinematic measures showed higher specificity values for distinguishing between normal and impaired cognition (MCI and AD), and higher sensitivity was obtained when distinguishing between impaired cognition levels (MCI vs. AD). Conclusion: The kinematic features of writing and drawing procedures, rather than the final product, may be a useful and objective complement to the clinical assessment of patients with cognitive impairment. PMID:28290244

A Virtual Dig--Joining Archaeology and Fiction to Promote Critical and Historical Thinking

ERIC Educational Resources Information Center

Cooper, David

2003-01-01

In this article, the author describes "Dr. Gesundheit and the Mysteries of Snake Valley," a mini-unit that he designed so that his middle-level students could learn to interpret archaeological diagrams, work cooperatively to discover relationships among their observations, and draw well-founded conclusions. The unit requires approximately four…

A Review and Perspective on Lean in Higher Education

ERIC Educational Resources Information Center

Balzer, William K.; Francis, David E.; Krehbiel, Timothy C.; Shea, Nicholas

2016-01-01

Purpose: The purpose of this paper is to synthesize the accumulated body of research on Lean in higher education, draw conclusions to help guide successful Lean implementations and propose future research directions to establish a rich base of knowledge that informs both practice and research. Design/methodology/approach This literature review…

A Project-based Spiral Curriculum for Introductory Courses in ChE: Part 3. Evaluation.

ERIC Educational Resources Information Center

DiBiasio, David; Comparini, Lisa; Dixon, Anthony G.; Clark, William M.

2001-01-01

Presents the third part of a series on the development and implementation of project-based spiral curriculum in chemical engineering. Focuses on the details of the assessment design, describes the results of the assessment, and draws conclusions about the success of the program. (Contains 18 references.) (ASK)

Treatment Integrity of Interventions with Children in the School Psychology Literature from 1995 to 2008

ERIC Educational Resources Information Center

Sanetti, Lisa M. Hagermoser; Gritter, Katie L.; Dobey, Lisa M.

2011-01-01

Increased accountability in education has resulted in a focus on implementing interventions with strong empirical support. Both student outcome and treatment integrity data are needed to draw valid conclusions about intervention effectiveness. Reviews of the literature in other fields (e.g., applied behavior analysis, prevention science) suggest…

Cortical Bases of Elementary Deductive Reasoning: Inference, Memory, and Metadeduction

ERIC Educational Resources Information Center

Reverberi, Carlo; Shallice, Tim; D'Agostini, Serena; Skrap, Miran; Bonatti, Luca L.

2009-01-01

Elementary deduction is the ability of unreflectively drawing conclusions from explicit or implicit premises, on the basis of their logical forms. This ability is involved in many aspects of human cognition and interactions. To date, limited evidence exists on its cortical bases. We propose a model of elementary deduction in which logical…

Are We Asking the Right Questions?: A Conceptual Review of the Educational Development Literature in Higher Education

ERIC Educational Resources Information Center

Amundsen, Cheryl; Wilson, Mary

2012-01-01

This is a conceptual review of the literature variously referred to as faculty development, educational development, instructional development, and academic development in higher education. Previous empirical reviews covering more than 30 years of published literature could draw only tentative and weak conclusions about the effectiveness of…

The Sweetest Chocolate Milk

ERIC Educational Resources Information Center

Newton, Kristie J.

2010-01-01

Using a nonroutine problem can be an effective way to encourage students to draw on prior knowledge, work together, and reach important conclusions about the mathematics they are learning. This article discusses a problem on the mathematical preparation of chocolate milk which was adapted from an old book of puzzles (Linn 1969) and has been used…

Third Culture Kids: Transition and Persistence When Repatriating to Attend University

ERIC Educational Resources Information Center

Jennison Smith, Virginia M

2011-01-01

Scope and Method of Study. This qualitative study used heuristic phenomenology and involved 20 interviews at 3 different sites, 2 focus groups, formal and informal observations, and the analysis of various artifacts including photos, drawings, and documents. Findings and Conclusions. Third culture kids are a diverse group of individuals who spent…

Development and Evaluation of a Model-Supported Scientific Inquiry Training Program for Elementary Teachers in Indonesia

ERIC Educational Resources Information Center

Ertikanto, Chandra; Herpratiwi; Yunarti, Tina; Saputra, Andrian

2017-01-01

A teacher training program, named Model-Supported Scientific Inquiry Training Program (MSSITP) has been successfully developed to improve the inquiry skills of Indonesian elementary teachers. The skills enhanced by MSSITP are defining problems, formulating hypotheses, planning and doing investigations, drawing conclusions, and communicating the…

The Importance of Statistical Modeling in Data Analysis and Inference

ERIC Educational Resources Information Center

Rollins, Derrick, Sr.

2017-01-01

Statistical inference simply means to draw a conclusion based on information that comes from data. Error bars are the most commonly used tool for data analysis and inference in chemical engineering data studies. This work demonstrates, using common types of data collection studies, the importance of specifying the statistical model for sound…

Measuring Change in Social Interaction Skills of Young Children with Autism

ERIC Educational Resources Information Center

Cunningham, Allison B.

2012-01-01

Designing effective treatments for improving early social behaviors in autism has been identified as a critical research need. One barrier to drawing conclusions about optimal treatments for children with autism is the use of highly varied dependent measures in the treatment literature. Contributing to this is the absence of "gold standard"…

Conclusion: Women around the World Reshaping Leadership for Education

ERIC Educational Resources Information Center

Grogan, Margaret

2010-01-01

Purpose: This short essay aims to reflect on the global experiences women in education have had in becoming leaders as noted in the articles in this special issue on women's leadership. Design/methodology/approach: The essay draws upon relevant historical and contemporary literature about women in the professions and in the workforce. Findings:…

Forces of the Wild. Nature. Teacher's Guide.

ERIC Educational Resources Information Center

Brown, Jordan

This curriculum guide was developed for use with public television's Nature series. The materials in the guide are designed to help students actively participate in the study and experience of nature. Students are encouraged to view the programs as a scientist would, observing natural phenomena and drawing conclusions. Each lesson in the Teacher's…

Comparing Societies from the 1500s in the Sixth Grade

ERIC Educational Resources Information Center

Matson, Trista; Henning, Mary Beth

2008-01-01

Inquiry is the process by which teachers give students an open-ended question, and then students investigate the evidence and draw conclusions based upon their findings. This method promotes critical thinking, as students cite evidence to support their opinions. Inquiry is most effective when it builds upon students' prior knowledge. To promote…

6883 Maintenance Training Simulator Development Utilizing Imagery Techniques.

DTIC Science & Technology

1980-05-01

increased motivation (as by its game-like setting), etc. These questions are left for future inquiry. 26 CONCLUSIONS AND RECOMMENDATIONS The imagery training...the output of power supply PS4 ." 46. 46 ; 20b. Read instructions (imagery group only). "To ready the board, take the one drawing that is titled

Great Explorations in Mathematics: Grades 5-8. Teacher's Edition.

ERIC Educational Resources Information Center

Dyches, Richard W.; And Others

This volume is a teacher's edition in a series of books that contain open-ended exploration activities and experiments. These activities allow and encourage students to set their own goals, use their own creativity and ideas, investigate the wonders of nature, learn about the workings of real businesses, and draw conclusions from their…

A Challenge to Vocational Educators. Patrick J. O'Connor Distinguished Scholars. 1994 Papers.

ERIC Educational Resources Information Center

Phillips, Maria; Burrell, Lewis

This document contains two papers dealing with challenges facing vocational educators. "Producing a Competent Workforce for the Year 2000: Industry Expectations of Education" (Lewis Burrell) draws the following conclusions: (1) employers and educators need to form a close coalition to plan, design, and execute a system of education and training…

Functional Grammar in the Context of Linguistic Applications in Turkish Language Teaching

ERIC Educational Resources Information Center

Epcacan, Cahit

2013-01-01

In the last century, language researches adopted the scientific method and linguistics became an autonomous discipline. Linguistics is a framework concept that analyzes all languages in the world in various contexts according to its own rules and draws conclusions using the systematic approach. Functional linguistics is a linguistic trend that…

International Comparisons and Sensitivity to Instruction

ERIC Educational Resources Information Center

Wiliam, Dylan

2008-01-01

While international comparisons such as those provided by PISA may be meaningful in terms of overall judgements about the performance of educational systems, caution is needed in terms of more fine-grained judgements. In particular it is argued that the results of PISA to draw conclusions about the quality of instruction in different systems is…

How Broad Liberal Arts Training Produces Phd Economists: Carleton's Story

ERIC Educational Resources Information Center

Bourne, Jenny; Grawe, Nathan D.

2015-01-01

Several recent studies point to strong performance in economics PhD programs of graduates from liberal arts colleges. While every undergraduate program is unique and the likelihood of selection bias combines with small sample sizes to caution against drawing strong conclusions, the authors reflect on their experience at Carleton College to…

Review of Family Financial Decision Making: Suggestions for Future Research and Implications for Financial Education

ERIC Educational Resources Information Center

Kim, Jinhee; Gutter, Michael S.; Spangler, Taylor

2017-01-01

This article reviews the theories and literature in intrahousehold financial decisions, spousal partners and financial decision making, family system and financial decision process, children, and financial decisions. The article draws conclusions from the literature review and discusses directions for future research and educational programs. Most…

Exploring the Self-concept of Adults with Mild Learning Disabilities

ERIC Educational Resources Information Center

Pestana, Claudio

2015-01-01

This qualitative study aimed to add to the research on the self-concept of adults with mild learning disabilities and to generate a deeper understanding of their self-perceptions rather than draw generalised quantitative conclusions. Eight adults diagnosed with mild learning disabilities receiving support from a supported living project were…

Thick Descriptions: A Language for Articulating Ethnographic Media Technology.

ERIC Educational Resources Information Center

Goldman-Segall, Ricki

"Thick descriptions" are descriptions that are layered enough to draw conclusions and uncover the intentions of a given act, event, or process. In a video environment, thick descriptions are images, gestures, or sequences that convey meaning. Neither the quantity nor the resolution of the images makes the descriptions thick. Thickness is…

Tracer Evolution at High Latitudes in Winter (SOLVE)

NASA Technical Reports Server (NTRS)

Plumb, R. Alan

2001-01-01

Prior to the SOLVE deployment, we modified and ran a chemical transport model (CTM) to set up a stratospheric climatology for 1 September 1999. During and immediately following the SOLVE deployments, we ran the model in near-real-time and used these results in conjunction with SOLVE observations to draw conclusions about stratospheric transport.

Quantitative Data Analysis--In the Graduate Curriculum

ERIC Educational Resources Information Center

Albers, Michael J.

2017-01-01

A quantitative research study collects numerical data that must be analyzed to help draw the study's conclusions. Teaching quantitative data analysis is not teaching number crunching, but teaching a way of critical thinking for how to analyze the data. The goal of data analysis is to reveal the underlying patterns, trends, and relationships of a…

Dominant Personality Types in Public Accounting: Selection Bias or Indoctrinated?

ERIC Educational Resources Information Center

Burton, Hughlene; Daugherty, Brian; Dickins, Denise; Schisler, Dan

2016-01-01

Prior studies concerning the personality type and preferences of accountants generally draw conclusions based upon the reports of either practicing accountants, or accounting students, at a single point in time. So while much is known about the personality type of accountants in general, left unexplored is the question of whether public…

Ancient India: The Asiatic Ethiopians.

ERIC Educational Resources Information Center

Scott, Carolyn McPherson

This curriculum unit was developed by a participant in the 1993 Fulbright-Hays Program "India: Continuity and Change." The unit attempts to place India in the "picture frame" of the ancient world as a part of a whole, not as a separate entity. Reading materials enable students to draw broader general conclusions based on the…

Professional Development for School Improvement: The Case of Indiana

ERIC Educational Resources Information Center

Ruddy, Anne-Maree; Prusinski, Ellen

2012-01-01

Drawing on data collected during an evaluation of Indiana schools receiving Title I 1003(g) School Improvement Fund grants in the 2008-2009 school year, this article explores how professional development can be used to support school improvement efforts. This article upholds the conclusion that when activities support the development of a…

Building bridges: marketing managed care to ethnically diverse populations.

PubMed

Rosen, M B

1996-12-01

America's population "stew" creates specific challenges to health plans attempting to reach ethnically differentiated enrollee groups. In this article, the author provides snapshots of four ethnic groups, suggests some marketing considerations when preparing communications to these groups, and helps draw some conclusions about marketing managed care products to a culturally diverse population.

Making Sense of Undergraduate Students' Reflections as They Learn through Writing an Action Research Proposal

ERIC Educational Resources Information Center

Maoto, S.

2011-01-01

This article explores learning opportunities offered by students' written reflections as they learn through writing an action research proposal. From tapping into students' reported struggles, I analysed data using three stages of qualitative data analysis: data reduction, data display, and conclusion drawing (Miles and Huberman 1994). It emerged…

Inquiry-Based Learning Approach in Physical Education: Stimulating and Engaging Students in Physical and Cognitive Learning

ERIC Educational Resources Information Center

Østergaard, Lars Domino

2016-01-01

Inquiry is an approach that promotes engagement, motivation and learning, and which involves use of cognitive knowledge, bodily experience and communicative skills. Usually the inquiry method with skills like observations, planning, investigations, experimenting and drawing conclusions is related to natural sciences, but this paper describes an…

The Theory and Practice of Alternative Certification: Implications for the Improvement of Teaching.

ERIC Educational Resources Information Center

Hawley, Willis D.

1990-01-01

Identifies questions related to the processes and consequences of alternative teacher certification (AC), answers questions with research-based facts, proposes key elements of a model AC program, and draws conclusions about the directions AC may take and its probable effects on educational reform and on the professionalization of teaching. (SM)

The Dark Side of the Tube

ERIC Educational Resources Information Center

Wagler, Amy; Wagler, Ron

2014-01-01

Every high school graduate should be able to use data analysis and statistical reasoning to draw conclusions about the world. Two core statistical concepts for students to understand are the role of variability in measures and evaluating the effect of a variable. In the activity presented in this article, students investigate a scientific question…

Improving Large Cetacean Implantable Satellite Tag Designs to Maximize Tag Robustness and Minimize Health Effects to Individual Animals

DTIC Science & Technology

2015-09-30

Olympia, WA, 98501 & National Marine Mammal Laboratory Alaska Fisheries Science Center, NOAA Fisheries 7600 Sand Point Way NE Seattle, WA...to Maximize Tag Robustness and Minimize Health Effects to Individual Animals Alexandre N. Zerbini Cascadia Research Collective 218 ½ 4 th Ave W...available to the marine mammal community after the conclusion of the project. This study has been carried out by scientists and engineers from eight

E-Beam Capture Aid Drawing Based Modelling on Cell Biology

NASA Astrophysics Data System (ADS)

Hidayat, T.; Rahmat, A.; Redjeki, S.; Rahman, T.

2017-09-01

The objectives of this research are to find out how far Drawing-based Modeling assisted with E-Beam Capture could support student’s scientific reasoning skill using Drawing - based Modeling approach assisted with E-Beam Capture. The research design that is used for this research is the Pre-test and Post-test Design. The data collection of scientific reasoning skills is collected by giving multiple choice questions before and after the lesson. The data analysis of scientific reasoning skills is using scientific reasoning assessment rubric. The results show an improvement of student’s scientific reasoning in every indicator; an improvement in generativity which shows 2 students achieving high scores, 3 students in elaboration reasoning, 4 students in justification, 3 students in explanation, 3 students in logic coherency, 2 students in synthesis. The research result in student’s explanation reasoning has the highest number of students with high scores, which shows 20 students with high scores in the pre-test and 23 students in post-test and synthesis reasoning shows the lowest number, which shows 1 student in the pretest and 3 students in posttest. The research result gives the conclusion that Drawing-based Modeling approach assisted with E-Beam Capture could not yet support student’s scientific reasoning skills comprehensively.

An exploratory study of the potential learning benefits for medical students in collaborative drawing: creativity, reflection and ‘critical looking’

PubMed Central

2013-01-01

Background Building on a series of higher educational arts/medicine initiatives, an interdisciplinary drawing module themed on the human body was developed for both year 3 Craft students and year 3 Medicine degree students. This became the subject of a research project exploring how the collaborative approach to drawing adopted on this module impacted on the students’ learning. In this article, emphasis is given to issues thought to have most potential relevance to medical education. Methods Using an ethnographic research design, the methods adopted were: direct observation of all aspects of the module sessions, audio and video recordings and photographs of the sessions, the incorporation of a semi-structured discussion at the end of each session, and anonymous student questionnaires. Results A number of key themes emerged. The complex, phased and multi-sensory nature of the ‘critical looking’ skills developed through the drawing exercises was seen as of potential value in medical education, being proposed as analogous to processes involved in clinical examination and diagnosis. The experience of interdisciplinary collaborative drawing was significant to the students as a creative, participatory and responsive form of learning. The emphasis on the physical experience of drawing and the thematic use of the human body as drawing subject led to reflective discussions about bodily knowledge and understanding. There were indications that students had a meta-cognitive awareness of the learning shifts that had occurred and the sessions provoked constructive self-reflective explorations of pre-professional identity. Conclusions This preliminary study suggests, through the themes identified, that there may be potential learning outcomes for medical students in this model of interdisciplinary collaborative drawing of the human body. Further research is needed to explore their applicability and value to medical education. There is a need to explore in more depth the beliefs, motivations and learning styles of medical students opting for the module, the significance and weighting of different learning and teaching elements in the module and the impact of the learning on medical students in the immediate post-module phase. PMID:23773830

Controlling Fiber Morphology in Simultaneous Centrifugal Spinning and Photopolymerization

NASA Astrophysics Data System (ADS)

Fang, Yichen; Dulaney, Austin; Ellison, Christopher

2015-03-01

Current synthetic fiber manufacturing technologies use either solvent or heat to transform a solid preformed polymer into a liquid before applying a force to draw the liquid into fiber. While the use of solvent poses concerns regarding process safety and environmental impact, the use of heat may also lead to polymer degradation and excessive energy consumption. To address these critical challenges, here we present an alternative fiber manufacturing method that encompasses extruding a monomer solution through an orifice, drawing it using centrifugal Forcespinning and polymerizing the monomer jet into solid fiber in flight using UV initiated thiol-ene chemistry. This method not only negates the use of both heat and solvent, but also produces fibers that are highly crosslinked, mechanically robust, and thermally stable. In this process, the balance between curing kinetics, fiber flight time, and solution viscoelasticity is essential. Studies were conducted to quantitatively investigate the effect of these factors on fiber formation and morphology. An operating diagram was developed to show how the intricate interplay of these factors led to the formation of smooth fibers and other undesirable fiber defects, such as beads-on-string, fused fibers, and droplets.

Application of the aqueous porous pathway model to quantify the effect of sodium lauryl sulfate on ultrasound-induced skin structural perturbation.

PubMed

Polat, Baris E; Seto, Jennifer E; Blankschtein, Daniel; Langer, Robert

2011-04-01

This study investigated the effect of sodium lauryl sulfate (SLS) on skin structural perturbation when utilized simultaneously with low-frequency sonophoresis (LFS). Pig full-thickness skin (FTS) and pig split-thickness skin (STS) treated with LFS/SLS and LFS were analyzed in the context of the aqueous porous pathway model to quantify skin perturbation through changes in skin pore radius and porosity-to-tortuosity ratio (ε/τ). In addition, skin treatment times required to attain specific levels of skin electrical resistivity were analyzed to draw conclusions about the effect of SLS on reproducibility and predictability of skin perturbation. We found that LFS/SLS-treated FTS, LFS/SLS-treated STS, and LFS-treated FTS exhibited similar skin perturbation. However, LFS-treated STS exhibited significantly higher skin perturbation, suggesting greater structural changes to the less robust STS induced by the purely physical enhancement mechanism of LFS. Evaluation of ε/τ values revealed that LFS/SLS-treated FTS and STS have similar transport pathways, whereas LFS-treated FTS and STS have lower ε/τ values. In addition, LFS/SLS treatment times were much shorter than LFS treatment times for both FTS and STS. Moreover, the simultaneous use of SLS and LFS not only results in synergistic enhancement, as reflected in the shorter skin treatment times, but also in more predictable and reproducible skin perturbation. Copyright © 2010 Wiley-Liss, Inc.

Whole Grains, Type 2 Diabetes, Coronary Heart Disease, and Hypertension: Links to the Aleurone preferred over Indigestible Fiber

PubMed Central

Lillioja, Stephen; Neal, Andrew L; Tapsell, Linda; Jacobs, David R

2012-01-01

Higher whole grain cereal intakes are associated with substantially lower risks of type 2 diabetes, coronary heart disease, and hypertension. These reduced risks have been established in large prospective studies that now include millions of person-years of follow-up. We analyze the results of 11 major prospective studies to provide recommendations about whole grain consumption. The following review establishes the amount of whole grains that should ideally be consumed based on prospective evidence; defines the nature of whole grains; identifies that the whole grain evidence is robust and not due to confounding; and provides a detailed assessment of several potential mechanisms for the effect of whole grains on health. We draw the following conclusions. Firstly, to maintain health, 40 grams or more of whole grains should be consumed daily. This is about a bowl of whole grain breakfast cereal daily, but 80% of the population does not achieve this. Secondly, aleurone in bran is a critical grain component generally overlooked in favor of indigestible fiber. Live aleurone cells constitute 50% of millers’ bran. They store minerals, protein, and the antioxidant ferulic acid, and are clearly more than just indigestible fiber. Finally, we suggest potential roles for magnesium, zinc, and ferulic acid in the development of chronic disease. If the results of prospective studies were applied to the life-style practices of modern societies there exists the potential for enormous personal health and public financial benefits. PMID:23355358

Evaluating Recommendation Systems

NASA Astrophysics Data System (ADS)

Shani, Guy; Gunawardana, Asela

Recommender systems are now popular both commercially and in the research community, where many approaches have been suggested for providing recommendations. In many cases a system designer that wishes to employ a recommendation system must choose between a set of candidate approaches. A first step towards selecting an appropriate algorithm is to decide which properties of the application to focus upon when making this choice. Indeed, recommendation systems have a variety of properties that may affect user experience, such as accuracy, robustness, scalability, and so forth. In this paper we discuss how to compare recommenders based on a set of properties that are relevant for the application. We focus on comparative studies, where a few algorithms are compared using some evaluation metric, rather than absolute benchmarking of algorithms. We describe experimental settings appropriate for making choices between algorithms. We review three types of experiments, starting with an offline setting, where recommendation approaches are compared without user interaction, then reviewing user studies, where a small group of subjects experiment with the system and report on the experience, and finally describe large scale online experiments, where real user populations interact with the system. In each of these cases we describe types of questions that can be answered, and suggest protocols for experimentation. We also discuss how to draw trustworthy conclusions from the conducted experiments. We then review a large set of properties, and explain how to evaluate systems given relevant properties. We also survey a large set of evaluation metrics in the context of the properties that they evaluate.

Biological treatments in giant cell arteritis & Takayasu arteritis.

PubMed

Samson, Maxime; Espígol-Frigolé, Georgina; Terrades-García, Nekane; Prieto-González, Sergio; Corbera-Bellalta, Marc; Alba-Rovira, Roser; Hernández-Rodríguez, José; Audia, Sylvain; Bonnotte, Bernard; Cid, Maria C

2018-04-01

Giant cell arteritis (GCA) and Takayasu arteritis (TAK) are the two main large vessel vasculitides. They share some similarities regarding their clinical, radiological and histological presentations but some pathogenic processes in GCA and TAK are activated differently, thus explaining their different sensitivity to biological therapies. The treatment of GCA and TAK essentially relies on glucocorticoids. However, thanks to major progress in our understanding of their pathogenesis, the role of biological therapies in the treatment of these two vasculitides is expanding, especially in relapsing or refractory diseases. In this review, the efficacy, the safety and the limits of the main biological therapies ever tested in GCA and TAK are discussed. Briefly, anti TNF-α agents appear to be effective in treating TAK but not GCA. Recent randomized placebo-controlled trials have reported on the efficacy and safety of abatacept and mostly tocilizumab in inducing and maintaining remission of GCA. Abatacept was not effective in TAK and robust data are still lacking to draw any conclusions concerning the use of tocilizumab in TAK. Furthermore, ustekinumab appears promising in relapsing/refractory GCA whereas rituximab has been reported to be effective in only a few cases of refractory TAK patients. If a biological therapy is indicated, and in light of the data discussed in this review, the first choice would be tocilizumab in GCA and anti-TNF-α agents (mainly infliximab) in TAK. Copyright © 2017 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

Projections of white and black older adults without living kin in the United States, 2015 to 2060.

PubMed

Verdery, Ashton M; Margolis, Rachel

2017-10-17

Close kin provide many important functions as adults age, affecting health, financial well-being, and happiness. Those without kin report higher rates of loneliness and experience elevated risks of chronic illness and nursing facility placement. Historical racial differences and recent shifts in core demographic rates suggest that white and black older adults in the United States may have unequal availability of close kin and that this gap in availability will widen in the coming decades. Whereas prior work explores the changing composition and size of the childless population or those without spouses, here we consider the kinless population of older adults with no living close family members and how this burden is changing for different race and sex groups. Using demographic microsimulation and the United States Census Bureau's recent national projections of core demographic rates by race, we examine two definitions of kinlessness: those without a partner or living children, and those without a partner, children, siblings, or parents. Our results suggest dramatic growth in the size of the kinless population as well as increasing racial disparities in percentages kinless. These conclusions are driven by declines in marriage and are robust to different assumptions about the future trajectory of divorce rates or growth in nonmarital partnerships. Our findings draw attention to the potential expansion of older adult loneliness, which is increasingly considered a threat to population health, and the unequal burden kinlessness may place on black Americans.

What impact do assumptions about missing data have on conclusions? A practical sensitivity analysis for a cancer survival registry.

PubMed

Smuk, M; Carpenter, J R; Morris, T P

2017-02-06

Within epidemiological and clinical research, missing data are a common issue and often over looked in publications. When the issue of missing observations is addressed it is usually assumed that the missing data are 'missing at random' (MAR). This assumption should be checked for plausibility, however it is untestable, thus inferences should be assessed for robustness to departures from missing at random. We highlight the method of pattern mixture sensitivity analysis after multiple imputation using colorectal cancer data as an example. We focus on the Dukes' stage variable which has the highest proportion of missing observations. First, we find the probability of being in each Dukes' stage given the MAR imputed dataset. We use these probabilities in a questionnaire to elicit prior beliefs from experts on what they believe the probability would be in the missing data. The questionnaire responses are then used in a Dirichlet draw to create a Bayesian 'missing not at random' (MNAR) prior to impute the missing observations. The model of interest is applied and inferences are compared to those from the MAR imputed data. The inferences were largely insensitive to departure from MAR. Inferences under MNAR suggested a smaller association between Dukes' stage and death, though the association remained positive and with similarly low p values. We conclude by discussing the positives and negatives of our method and highlight the importance of making people aware of the need to test the MAR assumption.

Properties of sunspot cycles and hemispheric wings since the 19th century

NASA Astrophysics Data System (ADS)

Leussu, Raisa; Usoskin, Ilya G.; Arlt, Rainer; Mursula, Kalevi

2016-08-01

Aims: The latitudinal evolution of sunspot emergence over the course of the solar cycle, the so-called butterfly diagram, is a fundamental property of the solar dynamo. Here we present a study of the butterfly diagram of sunspot group occurrence for cycles 7-10 and 11-23 using data from a recently digitized sunspot drawings by Samuel Heinrich Schwabe in 1825-1867, and from RGO/USAF/NOAA(SOON) compilation of sunspot groups in 1874-2015. Methods: We developed a new, robust method of hemispheric wing separation based on an analysis of long gaps in sunspot group occurrence in different latitude bands. The method makes it possible to ascribe each sunspot group to a certain wing (solar cycle and hemisphere), and separate the old and new cycle during their overlap. This allows for an improved study of solar cycles compared to the common way of separating the cycles. Results: We separated each hemispheric wing of the butterfly diagram and analysed them with respect to the number of groups appearing in each wing, their lengths, hemispheric differences, and overlaps. Conclusions: The overlaps of successive wings were found to be systematically longer in the northern hemisphere for cycles 7-10, but in the southern hemisphere for cycles 16-22. The occurrence of sunspot groups depicts a systematic long-term variation between the two hemispheres. During Schwabe time, the hemispheric asymmetry was north-dominated during cycle 9 and south-dominated during cycle 10.

Economic conditions, illicit drug use, and substance use disorders in the United States.

PubMed

Carpenter, Christopher S; McClellan, Chandler B; Rees, Daniel I

2017-03-01

We provide the first analysis of the relationship between economic conditions and the use of illicit drugs other than marijuana. Drawing on US data from 2002 to 2015, we find mixed evidence on the cyclicality of illicit drug use. However, we find robust evidence that economic downturns lead to increases in the intensity of prescription pain reliever use as well as increases in clinically relevant substance use disorders involving opioids. These effects are concentrated among working-age white males with low educational attainment. We conclude that policymakers should consider devoting more, not fewer, resources to treating substance use disorders during economic downturns. Copyright © 2016 Elsevier B.V. All rights reserved.

Cultivating Sustainable and Authentic Service-Learning Partnerships in the Environmental Sciences

NASA Astrophysics Data System (ADS)

Ivanochko, Tara; Grain, Kari

2017-04-01

The two-term, community service-learning capstone course for Environmental Sciences at the University of British Columbia, Canada, aims to support both community and students using authentic science practice in service of the community. During the course development, we implemented a routine process for student and community feedback, instructor reflection and course revision. Drawing on data from 23 interviews and 9 focus groups collected over three years, findings from this study highlight ways that community partnerships can be sustained while students have an authentic science experience. Based on data collected from community partners, we highlight the key processes, challenges, successes, and practical considerations in the creation and sustainability of a scientifically robust service-learning course.

Invariant features of spatial inequality in consumption: The case of India

NASA Astrophysics Data System (ADS)

Chatterjee, Arnab; Chakrabarti, Anindya S.; Ghosh, Asim; Chakraborti, Anirban; Nandi, Tushar K.

2016-01-01

We study the distributional features and inequality of consumption expenditure across India, for different states, castes, religion and urban-rural divide. We find that even though the aggregate measures of inequality are fairly diversified across states, the consumption distributions show near identical statistics, once properly normalized. This feature is seen to be robust with respect to variations in sociological and economic factors. We also show that state-wise inequality seems to be positively correlated with growth which is in accord with the traditional idea of Kuznets' curve. We present a brief model to account for the invariance found empirically and show that better but riskier technology draws can create a positive correlation between inequality and growth.

Family and Teacher Characteristics as Predictors of Parent Involvement in Education During Early Childhood Among Afro-Caribbean and Latino Immigrant Families.

PubMed

Calzada, Esther J; Huang, Keng-Yen; Hernandez, Miguel; Soriano, Erika; Acra, C Francoise; Dawson-McClure, Spring; Kamboukos, Dimitra; Brotman, Laurie

2015-10-01

Parent involvement is a robust predictor of academic achievement, but little is known about school- and home-based involvement in immigrant families. Drawing on ecological theories, the present study examined contextual characteristics as predictors of parent involvement among Afro-Caribbean and Latino parents of young students in urban public schools. Socioeconomic disadvantage was associated with lower home-based involvement. Several factors were associated with higher involvement, including parents' connection to their culture of origin and to U.S. culture, engagement practices by teachers and parent-teacher ethnic consonance (for Latinos only). Findings have implications for promoting involvement among immigrant families of students in urban schools.

Walking on water: the biomechanics of Michael A. MacConaill (1902-1987).

PubMed

Prendergast, P J; Lee, T C

2006-01-01

Biomechanics is a subject that draws on knowledge from many disciplines. One of its great practitioners in the last century was the Irish anatomist M.A. MacConaill. In this paper, we review some of MacConaill's fundamental contributions to biomechanics, namely: the hydrodynamic theory of synovial joint lubrication, the kinematics of joint motion and conjunct rotations; and the theory of spurt and shunt muscles. The aim is to revisit these topics in the light of current research, and to draw some conclusions about the import of his research in the context of recent developments in the field. The paper concludes with a discussion of science in Ireland, the development of the field of biomechanics since MacConaill's time, and some other matters.

Robust Fault Detection Using Robust Z1 Estimation and Fuzzy Logic

NASA Technical Reports Server (NTRS)

Curry, Tramone; Collins, Emmanuel G., Jr.; Selekwa, Majura; Guo, Ten-Huei (Technical Monitor)

2001-01-01

This research considers the application of robust Z(sub 1), estimation in conjunction with fuzzy logic to robust fault detection for an aircraft fight control system. It begins with the development of robust Z(sub 1) estimators based on multiplier theory and then develops a fixed threshold approach to fault detection (FD). It then considers the use of fuzzy logic for robust residual evaluation and FD. Due to modeling errors and unmeasurable disturbances, it is difficult to distinguish between the effects of an actual fault and those caused by uncertainty and disturbance. Hence, it is the aim of a robust FD system to be sensitive to faults while remaining insensitive to uncertainty and disturbances. While fixed thresholds only allow a decision on whether a fault has or has not occurred, it is more valuable to have the residual evaluation lead to a conclusion related to the degree of, or probability of, a fault. Fuzzy logic is a viable means of determining the degree of a fault and allows the introduction of human observations that may not be incorporated in the rigorous threshold theory. Hence, fuzzy logic can provide a more reliable and informative fault detection process. Using an aircraft flight control system, the results of FD using robust Z(sub 1) estimation with a fixed threshold are demonstrated. FD that combines robust Z(sub 1) estimation and fuzzy logic is also demonstrated. It is seen that combining the robust estimator with fuzzy logic proves to be advantageous in increasing the sensitivity to smaller faults while remaining insensitive to uncertainty and disturbances.

Effect of intermittent feedback control on robustness of human-like postural control system

NASA Astrophysics Data System (ADS)

Tanabe, Hiroko; Fujii, Keisuke; Suzuki, Yasuyuki; Kouzaki, Motoki

2016-03-01

Humans have to acquire postural robustness to maintain stability against internal and external perturbations. Human standing has been recently modelled using an intermittent feedback control. However, the causality inside of the closed-loop postural control system associated with the neural control strategy is still unknown. Here, we examined the effect of intermittent feedback control on postural robustness and of changes in active/passive components on joint coordinative structure. We implemented computer simulation of a quadruple inverted pendulum that is mechanically close to human tiptoe standing. We simulated three pairs of joint viscoelasticity and three choices of neural control strategies for each joint: intermittent, continuous, or passive control. We examined postural robustness for each parameter set by analysing the region of active feedback gain. We found intermittent control at the hip joint was necessary for model stabilisation and model parameters affected the robustness of the pendulum. Joint sways of the pendulum model were partially smaller than or similar to those of experimental data. In conclusion, intermittent feedback control was necessary for the stabilisation of the quadruple inverted pendulum. Also, postural robustness of human-like multi-link standing would be achieved by both passive joint viscoelasticity and neural joint control strategies.

Effect of intermittent feedback control on robustness of human-like postural control system.

PubMed

Tanabe, Hiroko; Fujii, Keisuke; Suzuki, Yasuyuki; Kouzaki, Motoki

2016-03-02

Humans have to acquire postural robustness to maintain stability against internal and external perturbations. Human standing has been recently modelled using an intermittent feedback control. However, the causality inside of the closed-loop postural control system associated with the neural control strategy is still unknown. Here, we examined the effect of intermittent feedback control on postural robustness and of changes in active/passive components on joint coordinative structure. We implemented computer simulation of a quadruple inverted pendulum that is mechanically close to human tiptoe standing. We simulated three pairs of joint viscoelasticity and three choices of neural control strategies for each joint: intermittent, continuous, or passive control. We examined postural robustness for each parameter set by analysing the region of active feedback gain. We found intermittent control at the hip joint was necessary for model stabilisation and model parameters affected the robustness of the pendulum. Joint sways of the pendulum model were partially smaller than or similar to those of experimental data. In conclusion, intermittent feedback control was necessary for the stabilisation of the quadruple inverted pendulum. Also, postural robustness of human-like multi-link standing would be achieved by both passive joint viscoelasticity and neural joint control strategies.

Effect of intermittent feedback control on robustness of human-like postural control system

PubMed Central

Tanabe, Hiroko; Fujii, Keisuke; Suzuki, Yasuyuki; Kouzaki, Motoki

2016-01-01

Humans have to acquire postural robustness to maintain stability against internal and external perturbations. Human standing has been recently modelled using an intermittent feedback control. However, the causality inside of the closed-loop postural control system associated with the neural control strategy is still unknown. Here, we examined the effect of intermittent feedback control on postural robustness and of changes in active/passive components on joint coordinative structure. We implemented computer simulation of a quadruple inverted pendulum that is mechanically close to human tiptoe standing. We simulated three pairs of joint viscoelasticity and three choices of neural control strategies for each joint: intermittent, continuous, or passive control. We examined postural robustness for each parameter set by analysing the region of active feedback gain. We found intermittent control at the hip joint was necessary for model stabilisation and model parameters affected the robustness of the pendulum. Joint sways of the pendulum model were partially smaller than or similar to those of experimental data. In conclusion, intermittent feedback control was necessary for the stabilisation of the quadruple inverted pendulum. Also, postural robustness of human-like multi-link standing would be achieved by both passive joint viscoelasticity and neural joint control strategies. PMID:26931281

On the dust load and rainfall relationship in South Asia: an analysis from CMIP5

NASA Astrophysics Data System (ADS)

Singh, Charu; Ganguly, Dilip; Dash, S. K.

2018-01-01

This study is aimed at examining the consistency of the relationship between load of dust and rainfall simulated by different climate models and its implication for the Indian summer monsoon system. Monthly mean outputs of 12 climate models, obtained from the archive of the Coupled Model Intercomparison Project phase 5 (CMIP5) for the period 1951-2004, are analyzed to investigate the relationship between dust and rainfall. Comparative analysis of the model simulated precipitation with the India Meteorological Department (IMD) gridded rainfall, CRU TS3.21 and GPCP version 2.2 data sets show significant differences between the spatial patterns of JJAS rainfall as well as annual cycle of rainfall simulated by various models and observations. Similarly, significant inter-model differences are also noted in the simulation of load of dust, nevertheless it is further noted that most of the CMIP5 models are able to capture the major dust sources across the study region. Although the scatter plot analysis and the lead-lag pattern correlation between the dust load and the rainfall show strong relationship between the dust load over distant sources and the rainfall in the South Asian region in individual models, the temporal scale of this association indicates large differences amongst the models. Our results caution that it would be pre-mature to draw any robust conclusions on the time scale of the relationship between dust and the rainfall in the South Asian region based on either CMIP5 results or limited number of previous studies. Hence, we would like to emphasize upon the fact that any conclusions drawn on the relationship between the dust load and the South Asian rainfall using model simulation is highly dependent on the degree of complexity incorporated in those models such as the representation of aerosol life cycle, their interaction with clouds, precipitation and other components of the climate system.

Cost-Effectiveness of Collaborative Care for the Treatment of Depressive Disorders in Primary Care: A Systematic Review

PubMed Central

Grochtdreis, Thomas; Brettschneider, Christian; Wegener, Annemarie; Watzke, Birgit; Riedel-Heller, Steffi; Härter, Martin; König, Hans-Helmut

2015-01-01

Background For the treatment of depressive disorders, the framework of collaborative care has been recommended, which showed improved outcomes in the primary care sector. Yet, an earlier literature review did not find sufficient evidence to draw robust conclusions on the cost-effectiveness of collaborative care. Purpose To systematically review studies on the cost-effectiveness of collaborative care, compared with usual care for the treatment of patients with depressive disorders in primary care. Methods A systematic literature search in major databases was conducted. Risk of bias was assessed using the Cochrane Collaboration’s tool. Methodological quality of the articles was assessed using the Consensus on Health Economic Criteria (CHEC) list. To ensure comparability across studies, cost data were inflated to the year 2012 using country-specific gross domestic product inflation rates, and were adjusted to international dollars using purchasing power parities (PPP). Results In total, 19 cost-effectiveness analyses were reviewed. The included studies had sample sizes between n = 65 to n = 1,801, and time horizons between six to 24 months. Between 42% and 89% of the CHEC quality criteria were fulfilled, and in only one study no risk of bias was identified. A societal perspective was used by five studies. Incremental costs per depression-free day ranged from dominance to US$PPP 64.89, and incremental costs per QALY from dominance to US$PPP 874,562. Conclusion Despite our review improved the comparability of study results, cost-effectiveness of collaborative care compared with usual care for the treatment of patients with depressive disorders in primary care is ambiguous depending on willingness to pay. A still considerable uncertainty, due to inconsistent methodological quality and results among included studies, suggests further cost-effectiveness analyses using QALYs as effect measures and a time horizon of at least 1 year. PMID:25993034

The effectiveness of the Herbst appliance for patients with Class II malocclusion: a meta-analysis

PubMed Central

Yang, Xin; Zhu, Yafen; Long, Hu; Zhou, Yang; Jian, Fan; Ye, Niansong; Gao, Meiya

2016-01-01

Summary Objective: To systematically investigate review in literature the effects of the Herbst appliance for patients with Class II malocclusion patients. Method: We performed a comprehensive literature survey on PubMed, Web of Science, Embase, CENTRAL, SIGLE, and ClinicalTrial.gov up to December 2014. The selection criteria: randomized controlled trials or clinical controlled trials; using any kind of Herbst appliances to correct Class II division 1 malocclusions; skeletal and/or dental changes evaluated through lateral cephalograms. And the exclusion criteria: syndromic patients; individual case reports and series of cases; surgical interventions. Article screening, data extraction, assessment of risk of bias, and evaluation of evidence quality through GRADE were conducted independently by two well-trained orthodontic doctors. Consensus was made via group discussion of all authors when there is inconsistent information from the two. After that, sensitivity analysis and subgroup analysis were performed to evaluate the robustness of the meta-analysis. Results: Twelve clinical controlled trials meet the above-mentioned criteria, and were included in this analysis. All included studies have eleven measures taken during both active treatment effect and long term effect periods, including four angular ones (i.e., SNA, SNB, ANB, mandibular plane angle) and seven linear ones (i.e. Co-Go, Co-Gn, overjet, overbite, molar relationship, A point-OLp, Pg-OLp) during active treatment effect period were statistically pooled. Meta-analysis and sensitivity analysis demonstrated that all these measures showed consistent results except for SNA, ANB, and overbite. Subgroup analysis showed significant changes in SNA, overbite, and Pg-OLp. Publication bias was detected in SNB, mandibular plane angle, and A point-OLp. Conclusion: The Herbst appliance is effective for patients with Class II malocclusion in active treatment period. Especially, there are obvious changes on dental discrepancy and skeletal changes on Co-Gn. As to its long-term effects, more evidence is needed to draw conclusions. PMID:26306822

The Application of Orthophosphate to Reduce Elevated Copper Levels in a New Building with High DIC Water

EPA Science Inventory

Public water utilities in the United States are required to meet the 1991 Lead and Copper Rule action level of 1.3 mg/L for copper I drinking water. The effect of water chemistry on Cu(II) solubility has been studied, and drawing upon conclusions from this research , new copper ...

New Hydrokinetic Turbine for Free Surface Gravitational Wave Transformation

NASA Astrophysics Data System (ADS)

Berins, J.

2017-12-01

The present article deals with an alternative form of energy - the conversion of marine/ocean wave energy using an axial self-regulating blade (SB) hydrokinetic turbine (ASRBHK turbine). The article analyses the operation of the ASRBHK turbine and draws the resulting conclusions about the mechanism, in which the power transfer element is a self-regulating blade.

Teachers' Self-Perceptions in England and Germany: Methodological Nationalism and Negative Points of Reference in Comparative Research

ERIC Educational Resources Information Center

von Bargen, Imke

2017-01-01

The field of comparative education traditionally compares nations and cultures to gain a deeper understanding of educational phenomena. The nation-state often functions as the only unit of comparison, which increases methodological nationalism. It is dangerous to draw simplistic conclusions because they focus on national particularities alone and…

Source and Message Factors in Persuasion: A Reply to Stiff's Critique of the Elaboration Likelihood Model.

ERIC Educational Resources Information Center

Petty, Richard E.; And Others

1987-01-01

Answers James Stiff's criticism of the Elaboration Likelihood Model (ELM) of persuasion. Corrects certain misperceptions of the ELM and criticizes Stiff's meta-analysis that compares ELM predictions with those derived from Kahneman's elastic capacity model. Argues that Stiff's presentation of the ELM and the conclusions he draws based on the data…

"Teach For"/"Teach First" Candidates: What Conclusions Do They Draw from Their Time in Teaching?

ERIC Educational Resources Information Center

Rice, Suzanne; Volkoff, Veronica; Dulfer, Nicky

2015-01-01

"Teach For" and "Teach First" programs now constitute a significant pathway into teaching in a number of countries. One criterion for selection into these programs is leadership capacity, and evidence indicates that many candidates do move into leadership roles in education, business, and policy in the years following their…

Injury to plants from rapidly dropping temperature in Washington and northern Idaho

Treesearch

R. Daubenmire

1957-01-01

In nearly 70 years of recorded weather history, Washington and northern Idaho have on three occasions experienced exceptionally sharp freezes in late autumn or early winter that caused considerable damage to plants. A brief review of these events is warranted since the records are consistent enough to permit the drawing of significant conclusions.

Iniciativa sobre Efectividad: Primeros frutos (Initiative about Effectiveness: First Fruits).

ERIC Educational Resources Information Center

Moreno Garcia, Teresa, Ed.

2001-01-01

This Spanish- and Portuguese-language bulletin is a follow-up to No. 15 (PS 030 558), which examined some Effectiveness Initiative (EI) projects. This issue presents some beginning efforts to reflect on what has been learned through EI and to draw conclusions. The articles cover the results of EI projects from such angles as their relations with…

Effectiveness of e-Lab Use in Science Teaching at the Omani Schools

ERIC Educational Resources Information Center

Al Musawi, A.; Ambusaidi, A.; Al-Balushi, S.; Al-Balushi, K.

2015-01-01

Computer and information technology can be used so that students can individually, in groups, or by electronic demonstration experiment and draw conclusion for the required activities in an electronic form in what is now called "e-lab". It enables students to conduct experiments more flexibly and in an interactive way using multimedia.…

The Role of Social Networks in Physical and Relational Aggression among Young Adolescents

ERIC Educational Resources Information Center

Low, Sabina; Polanin, Joshua R.; Espelage, Dorothy L.

2013-01-01

Despite the veritable influence of the peer context on the elaboration of adolescent aggression, few studies of relational aggression have directly identified and measured peer groups, limiting our ability to draw formal conclusions about the level and nature of peer influence. The current study used a developmental framework to examine peer group…

Capacity Building through Integration and Transformational Leadership--A Case Study

ERIC Educational Resources Information Center

Stöcklin, Sacha

2011-01-01

This article suggests that educational managers can have an influence through leadership by establishing certain moderators that integrate and shape the faculty into a solid team working towards a high performing organisation. The study looks at a case in China and draws suggestions that could be used in other similar settings. The conclusion is…

The Psychologist's Troubled Background: Major Related Life Experiences of Psychology and Law Students

ERIC Educational Resources Information Center

Werz, Janina; Buechner, Vanessa L.

2017-01-01

This study explores major-related life experiences (MRLE) of psychology and law students to examine the stereotype of the wounded psychology student. Previous studies have shown that psychology students know people with mental disorders and are seeking treatment themselves. However, these studies do not allow drawing conclusions about the…

The Benefits of Florida's Test-Based Promotion System. Civic Report. No. 68

ERIC Educational Resources Information Center

Winters, Marcus A.

2012-01-01

State and municipal policymakers are increasingly addressing the practice of social promotion in schools--moving children along to the next grade whether or not they have mastered the curriculum--by mandating test-based grade promotion. This paper draws conclusions about the effects of a policy limiting social promotion. To do so, it employs a…

An Analysis of Female Lecturers' Participation in Civil Engineering Research and Development Activities at One Polytechnic in Zimbabwe

ERIC Educational Resources Information Center

Chikuvadze, Pinias; Matswetu, Vimbai Sharon; Mugijima, Samuel

2015-01-01

This study sought to explore female lecturers' participation in civil engineering research and development activities at one polytechnic in Zimbabwe. Case study design was chosen for this study to make predictions, narration of events, comparisons and drawing of conclusions. The female lecturers were purposively sampled to participate in the…

A Cross Canada Inventory: Evidence of 21st Century Educational Reform in Canada

ERIC Educational Resources Information Center

Burns, Amy

2017-01-01

This paper reports on an initial website review of Ministries of Education, provincial teacher associations and select school jurisdictions across Canada with respect to their publically available and visible policy commitments to 21st century educational reforms. This review was conducted for the purposes of drawing conclusions about the current…

Mobilizing Ethnic Equality in Admissions to Schools: Litigation, Politics, and Educational Change

ERIC Educational Resources Information Center

Perry-Hazan, Lotem; Perelstain, Oshrat

2018-01-01

This study explores the impact of litigation on the mobilization of ethnic equality in the admission to Haredi (ultra-Orthodox) schools in Israel, and examines the socio-political mechanisms that have shaped this impact. It uses a case-study approach and draws on an analysis of documents and interviews. The findings confirm the conclusions of…

Taking Care with Attachment Disorders and Autistic-Like Traits: The Potential Significance of Cognitive Markers

ERIC Educational Resources Information Center

Melling, Richard; Smethurst, Nicola

2017-01-01

The behaviours associated with the attachment disorders (ADs) appear to overlap substantially with those linked to the autism spectrum (AS). Given the similarities between the two conditions this article urges caution when drawing conclusions concerning the likely aetiology of presenting difficulties in any particular case. Attention is drawn to…

From Petrodollars to Petroeuros: Are the Dollar’s Days as an International Reserve Currency Drawing to an End?

DTIC Science & Technology

2003-11-03

price of oil less transparent, require continuous updating to minimize currency arbitrage , and could make the market less liquid as available capital...there are plenty of cheap ways for traders to hedge against currency risk if they are concerned about movements in the dollar. Conclusions

Feasibility and Behavioral Effects of an At-Home Multi-Night Sleep Restriction Protocol for Adolescents

ERIC Educational Resources Information Center

Beebe, Dean W.; Fallone, Gahan; Godiwala, Neha; Flanigan, Matt; Martin, David; Schaffner, Laura; Amin, Raouf

2008-01-01

Background: Sleep deprivation is common among adolescents and has been associated with adverse behavioral and educational outcomes. However, it is difficult to draw strong causal conclusions because of a dearth of experimental sleep research. In part, this appears related to methodological challenges when working with this population. This study…

Hazardous Waste Management and Community Involvement in Canada: The Case of Montreal's Rural-Urban Fringe.

ERIC Educational Resources Information Center

Andre, Pierre; And Others

1995-01-01

Deals with conflicts associated with the management, disposal, and storage of hazardous wastes from the perspective of interests expressed in the local community. Analyzes three case studies to demonstrate the changing roles and relative importance of local and nonlocal interests. Draws conclusions regarding the significance of the analysis for…

We Need to Teach for Ethical Conduct

ERIC Educational Resources Information Center

Sternberg, Robert J.

2009-01-01

Educators have a responsibility to teach students not only to be knowledgeable and intelligent, but also to use their knowledge and intelligence in ethical ways; that is, to be wise. In this essay, I first describe why we need to teach for ethical behavior. Then, I discuss how we can teach for ethical behavior. Finally, I draw some conclusions.

Recreating Realities: An Ethnographic/Case Study Approach to the Historic Composition Classroom.

ERIC Educational Resources Information Center

Claywell, Gina

Traditional histories of American college composition instruction in the 19th and 20th centuries examine primarily the textbooks used in those courses, then draw conclusions based on the content of those textbooks about the activities and attitudes expressed in the classroom. The canon of composition historiography is lacking in several ways: the…

Synthesis of Aryl-Substituted 2,4-Dinitrophenylamines: Nucleophilic Aromatic Substitution as a Problem-Solving and Collaborative-Learning Approach

ERIC Educational Resources Information Center

Santos, Elvira Santos; Garcia, Irma Cruz Gavilan; Gomez, Eva Florencia Lejarazo; Vilchis-Reyes, Miguel Angel

2010-01-01

A series of experiments based on problem-solving and collaborative-learning pedagogies are described that encourage students to interpret results and draw conclusions from data. Different approaches including parallel library synthesis, solvent variation, and leaving group variation are used to study a nucleophilic aromatic substitution of…

22 CFR 96.49 - Provision of medical and social information in incoming cases.

Code of Federal Regulations, 2010 CFR

2010-04-01

... on the known health risks in the specific region or country where the child resides. (e) If the... data and perceptions the individual used to draw his or her conclusions; (4) A review of...) Information about the full range of any tests performed on the child, including tests addressing known risk...

Educating for the Future in Family Life. Information Series No. 228.

ERIC Educational Resources Information Center

Simpson, Elizabeth J.

This paper utilizes knowledge gained from work on future issues related to families, the work of futurists on social trends and technological development, and recent studies in home economics to draw conclusions regarding what people will need to know in the 1980s and beyond to be intelligent consumers and effective homemakers. The first of six…

Putting Sociology First--Reconsidering the Role of the Social in "Nature of Science" Education

ERIC Educational Resources Information Center

Zemplen, Gabor A.

2009-01-01

Contrasting two examples from 2005, a creationism-trial and a recent textbook, the article shows two different ways of employing social considerations to demarcate science from non-science. Drawing conclusions from the comparison, and citing some of the leading proponents of science studies, the paper argues for a novel perspective in teaching…

The Impact of Adjacent-Dependencies and Staged-Input on the Learnability of Center-Embedded Hierarchical Structures

ERIC Educational Resources Information Center

Lai, Jun; Poletiek, Fenna H.

2011-01-01

A theoretical debate in artificial grammar learning (AGL) regards the learnability of hierarchical structures. Recent studies using an A[superscript n]B[superscript n] grammar draw conflicting conclusions ([Bahlmann and Friederici, 2006] and [De Vries et al., 2008]). We argue that 2 conditions crucially affect learning A[superscript…

Summary of Forest health monitoring: 2006 national technical report

Treesearch

Mark J. Ambrose

2009-01-01

Forest Health Monitoring (FHM), together with cooperating researchers both in and outside of the Forest Service, continues to investigate a variety of issues relating to forest health. This report provides some of the latest analyses and results. The broad range of indicators presented demonstrates one reason it can be difficult to draw general conclusions about the...

Barriers to Implementing Treatment Integrity Procedures in School Psychology Research: Survey of Treatment Outcome Researchers

ERIC Educational Resources Information Center

Sanetti, Lisa M. Hagermoser; DiGennaro Reed, Florence D.

2012-01-01

Treatment integrity data are essential to drawing valid conclusions in treatment outcome studies. Such data, however, are not always included in peer-reviewed research articles in school psychology or related fields. To gain a better understanding of why treatment integrity data are lacking in the school psychology research, we surveyed the…

Hydrostatic collapse research in support of the Oman India gas pipeline

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stark, P.R.; McKeehan, D.S.

1995-12-01

This paper provides a summary of the collapse test program conducted as part of the technical development for the Ultra Deep Oman to India Pipeline. The paper describes the motivation for conducting the collapse test program, outlines the test objectives and procedures, presents the results obtained, and draws conclusions on the factors affecting collapse resistance.

Villain or Savior? The American Discourse on Homework, 1850-2003

ERIC Educational Resources Information Center

Gill, Brian P.; Schlossman, Steven L.

2004-01-01

This article examines homework's place in American K-12 schooling over the last century and draws three main conclusions. First, homework has always aroused strong passions pro and con. Second, despite prominent press reports to the contrary in the early 20th century and again today, the best evidence suggests that most parents have consistently…

Trends in public attitudes towards the use of wildland fire

Treesearch

Katie Knotek

2006-01-01

This paper summarizes a select set of research studies conducted over the past 40 years, drawing conclusions on trends in public attitudes about the use of wildland fire in federally-designated Wilderness. The research includes trend studies conducted with visitors to Wilderness areas in Washington, Oregon, California, Idaho and Montana. Each research study used a...

An Experiment-Oriented Approach to Teaching the Kinetic Molecular Theory.

ERIC Educational Resources Information Center

Wiseman, Frank L., Jr.

1979-01-01

This paper reports an experiment in the teaching of the kinetic molecular theory to nonscience majors by the inquiry method. It allows the student to develop an essentially correct view of gases, liquids, and solids on the atomic or molecular level, and illustrates how one can draw conclusions about the molecular level by simple visual…

Digital clock drawing: Differentiating ‘thinking’ versus ‘doing’ in younger and older adults with depression

PubMed Central

Cohen, Jamie; Penney, Dana L.; Davis, Randall; Libon, David J.; Swenson, Rodney A.; Ajilore, Olusola; Kumar, Anand; Lamar, Melissa

2015-01-01

Objective Psychomotor slowing has been documented in depression. The digital Clock Drawing Test (dCDT) provides: i) a novel technique to assess both cognitive and motor aspects of psychomotor speed within the same task and ii) the potential to uncover subtleties of behavior not previously detected with non-digitized modes of data collection. Method Using digitized pen technology in 106 participants grouped by Age (younger/older) and Affect (euthymic/unmedicated depressed), we recorded cognitive and motor output by capturing how the clock is drawn rather than focusing on the final product. We divided time to completion (TTC) for Command and Copy conditions of the dCDT into metrics of percent of drawing (%Ink) versus non-drawing (%Think) time. We also obtained composite z-scores of cognition, including attention/ information processing (AIP), to explore associations of %Ink and %Think times to cognitive and motor performance. Results Despite equivalent TTC, %Ink and %Think Command times (Copy n.s.) were significant (AgeXAffect interaction:p=.03)—younger depressed spent a smaller proportion of time drawing relative to thinking compared to the older depressed group. Command %Think time negatively correlated with AIP in the older depressed group (r=−.46;p=.02). Copy %Think time negatively correlated with AIP in the younger depressed (r=−.47;p=.03) and older euthymic groups (r=−.51;p=.01). Conclusion The dCDT differentiated aspects of psychomotor slowing in depression regardless of age, while dCDT/cognitive associates for younger adults with depression mimicked patterns of older euthymics. PMID:25222513

Relations between Brain Structure and Attentional Function in Spina Bifida: Utilization of Robust Statistical Approaches

PubMed Central

Kulesz, Paulina A.; Tian, Siva; Juranek, Jenifer; Fletcher, Jack M.; Francis, David J.

2015-01-01

Objective Weak structure-function relations for brain and behavior may stem from problems in estimating these relations in small clinical samples with frequently occurring outliers. In the current project, we focused on the utility of using alternative statistics to estimate these relations. Method Fifty-four children with spina bifida meningomyelocele performed attention tasks and received MRI of the brain. Using a bootstrap sampling process, the Pearson product moment correlation was compared with four robust correlations: the percentage bend correlation, the Winsorized correlation, the skipped correlation using the Donoho-Gasko median, and the skipped correlation using the minimum volume ellipsoid estimator Results All methods yielded similar estimates of the relations between measures of brain volume and attention performance. The similarity of estimates across correlation methods suggested that the weak structure-function relations previously found in many studies are not readily attributable to the presence of outlying observations and other factors that violate the assumptions behind the Pearson correlation. Conclusions Given the difficulty of assembling large samples for brain-behavior studies, estimating correlations using multiple, robust methods may enhance the statistical conclusion validity of studies yielding small, but often clinically significant, correlations. PMID:25495830

Vegetation resurvey is robust to plot location uncertainty

PubMed Central

Kopecký, Martin; Macek, Martin

2017-01-01

Aim Resurveys of historical vegetation plots are increasingly used for the assessment of decadal changes in plant species diversity and composition. However, historical plots are usually relocated only approximately. This potentially inflates temporal changes and undermines results. Location Temperate deciduous forests in Central Europe. Methods To explore if robust conclusions can be drawn from resurvey studies despite location uncertainty, we compared temporal changes in species richness, frequency, composition and compositional heterogeneity between exactly and approximately relocated plots. We hypothesized that compositional changes should be lower and changes in species richness should be less variable on exactly relocated plots, because pseudo-turnover inflates temporal changes on approximately relocated plots. Results Temporal changes in species richness were not more variable and temporal changes in species composition and compositional heterogeneity were not higher on approximately relocated plots. Moreover, the frequency of individual species changed similarly on both plot types. Main conclusions The resurvey of historical vegetation plots is robust to uncertainty in original plot location and, when done properly, provides reliable evidence of decadal changes in plant communities. This provides important background for other resurvey studies and opens up the possibility for large-scale assessments of plant community change. PMID:28503083

Robust optical sensors for safety critical automotive applications

NASA Astrophysics Data System (ADS)

De Locht, Cliff; De Knibber, Sven; Maddalena, Sam

2008-02-01

Optical sensors for the automotive industry need to be robust, high performing and low cost. This paper focuses on the impact of automotive requirements on optical sensor design and packaging. Main strategies to lower optical sensor entry barriers in the automotive market include: Perform sensor calibration and tuning by the sensor manufacturer, sensor test modes on chip to guarantee functional integrity at operation, and package technology is key. As a conclusion, optical sensor applications are growing in automotive. Optical sensor robustness matured to the level of safety critical applications like Electrical Power Assisted Steering (EPAS) and Drive-by-Wire by optical linear arrays based systems and Automated Cruise Control (ACC), Lane Change Assist and Driver Classification/Smart Airbag Deployment by camera imagers based systems.

Evolving polycentric governance of the Great Barrier Reef

PubMed Central

Morrison, Tiffany H.

2017-01-01

A growing field of sustainability science examines how environments are transformed through polycentric governance. However, many studies are only snapshot analyses of the initial design or the emergent structure of polycentric regimes. There is less systematic analysis of the longitudinal robustness of polycentric regimes. The problem of robustness is approached by focusing not only on the structure of a regime but also on its context and effectiveness. These dimensions are examined through a longitudinal analysis of the Great Barrier Reef (GBR) governance regime, drawing on in-depth interviews and demographic, economic, and employment data, as well as organizational records and participant observation. Between 1975 and 2011, the GBR regime evolved into a robust polycentric structure as evident in an established set of multiactor, multilevel arrangements addressing marine, terrestrial, and global threats. However, from 2005 onward, multiscale drivers precipitated at least 10 types of regime change, ranging from contextual change that encouraged regime drift to deliberate changes that threatened regime conversion. More recently, regime realignment also has occurred in response to steering by international organizations and shocks such as the 2016 mass coral-bleaching event. The results show that structural density and stability in a governance regime can coexist with major changes in that regime’s context and effectiveness. Clear analysis of the vulnerability of polycentric governance to both diminishing effectiveness and the masking effects of increasing complexity provides sustainability science and governance actors with a stronger basis to understand and respond to regime change. PMID:28348238

Evolving polycentric governance of the Great Barrier Reef.

PubMed

Morrison, Tiffany H

2017-04-11

A growing field of sustainability science examines how environments are transformed through polycentric governance. However, many studies are only snapshot analyses of the initial design or the emergent structure of polycentric regimes. There is less systematic analysis of the longitudinal robustness of polycentric regimes. The problem of robustness is approached by focusing not only on the structure of a regime but also on its context and effectiveness. These dimensions are examined through a longitudinal analysis of the Great Barrier Reef (GBR) governance regime, drawing on in-depth interviews and demographic, economic, and employment data, as well as organizational records and participant observation. Between 1975 and 2011, the GBR regime evolved into a robust polycentric structure as evident in an established set of multiactor, multilevel arrangements addressing marine, terrestrial, and global threats. However, from 2005 onward, multiscale drivers precipitated at least 10 types of regime change, ranging from contextual change that encouraged regime drift to deliberate changes that threatened regime conversion. More recently, regime realignment also has occurred in response to steering by international organizations and shocks such as the 2016 mass coral-bleaching event. The results show that structural density and stability in a governance regime can coexist with major changes in that regime's context and effectiveness. Clear analysis of the vulnerability of polycentric governance to both diminishing effectiveness and the masking effects of increasing complexity provides sustainability science and governance actors with a stronger basis to understand and respond to regime change.

A distributed database view of network tracking systems

NASA Astrophysics Data System (ADS)

Yosinski, Jason; Paffenroth, Randy

2008-04-01

In distributed tracking systems, multiple non-collocated trackers cooperate to fuse local sensor data into a global track picture. Generating this global track picture at a central location is fairly straightforward, but the single point of failure and excessive bandwidth requirements introduced by centralized processing motivate the development of decentralized methods. In many decentralized tracking systems, trackers communicate with their peers via a lossy, bandwidth-limited network in which dropped, delayed, and out of order packets are typical. Oftentimes the decentralized tracking problem is viewed as a local tracking problem with a networking twist; we believe this view can underestimate the network complexities to be overcome. Indeed, a subsequent 'oversight' layer is often introduced to detect and handle track inconsistencies arising from a lack of robustness to network conditions. We instead pose the decentralized tracking problem as a distributed database problem, enabling us to draw inspiration from the vast extant literature on distributed databases. Using the two-phase commit algorithm, a well known technique for resolving transactions across a lossy network, we describe several ways in which one may build a distributed multiple hypothesis tracking system from the ground up to be robust to typical network intricacies. We pay particular attention to the dissimilar challenges presented by network track initiation vs. maintenance and suggest a hybrid system that balances speed and robustness by utilizing two-phase commit for only track initiation transactions. Finally, we present simulation results contrasting the performance of such a system with that of more traditional decentralized tracking implementations.

A robust data scaling algorithm to improve classification accuracies in biomedical data.

PubMed

Cao, Xi Hang; Stojkovic, Ivan; Obradovic, Zoran

2016-09-09

Machine learning models have been adapted in biomedical research and practice for knowledge discovery and decision support. While mainstream biomedical informatics research focuses on developing more accurate models, the importance of data preprocessing draws less attention. We propose the Generalized Logistic (GL) algorithm that scales data uniformly to an appropriate interval by learning a generalized logistic function to fit the empirical cumulative distribution function of the data. The GL algorithm is simple yet effective; it is intrinsically robust to outliers, so it is particularly suitable for diagnostic/classification models in clinical/medical applications where the number of samples is usually small; it scales the data in a nonlinear fashion, which leads to potential improvement in accuracy. To evaluate the effectiveness of the proposed algorithm, we conducted experiments on 16 binary classification tasks with different variable types and cover a wide range of applications. The resultant performance in terms of area under the receiver operation characteristic curve (AUROC) and percentage of correct classification showed that models learned using data scaled by the GL algorithm outperform the ones using data scaled by the Min-max and the Z-score algorithm, which are the most commonly used data scaling algorithms. The proposed GL algorithm is simple and effective. It is robust to outliers, so no additional denoising or outlier detection step is needed in data preprocessing. Empirical results also show models learned from data scaled by the GL algorithm have higher accuracy compared to the commonly used data scaling algorithms.

Daily and estrous rhythmicity of body temperature in domestic cattle

PubMed Central

Piccione, Giuseppe; Caola, Giovanni; Refinetti, Roberto

2003-01-01

Background Rhythmicity in core body temperature has been extensively studied in humans and laboratory animals but much less in farm animals. Extending the study of rhythmicity of body temperature to farm animals is important not only from a comparative perspective but also from an economic perspective, as greater knowledge of this process can lead to improvements in livestock production practices. In this study in cattle, we investigated the maturation of the daily rhythm of body temperature in newborn calves, characterized the parameters of the daily rhythm in young cows, and studied the oscillation in body temperature associated with the estrous cycle in adult cows. Results We found that the daily rhythm of body temperature is absent at birth but matures fully during the first two months of life. The mature rhythm had a mean level of 38.3°C, a range of excursion of 1.4°C, and was more robust than that of any mammalian species previously studied (90% of maximal robustness). Sexually mature cows also exhibited a robust estrous rhythm of body temperature. An elevation of about 1.3°C was observed every 21 days on the day of estrus. Small seasonal variations in this pattern were observed. Conclusion In conclusion, calves exhibit a very robust daily rhythm of body temperature, although this rhythm is absent at birth and develops during the first two months of life. Adult cows exhibit also 21-day rhythmicity in body temperature reflecting the duration of the estrous cycle. PMID:12882649

Optimization of cascading failure on complex network based on NNIA

NASA Astrophysics Data System (ADS)

Zhu, Qian; Zhu, Zhiliang; Qi, Yi; Yu, Hai; Xu, Yanjie

2018-07-01

Recently, the robustness of networks under cascading failure has attracted extensive attention. Different from previous studies, we concentrate on how to improve the robustness of the networks from the perspective of intelligent optimization. We establish two multi-objective optimization models that comprehensively consider the operational cost of the edges in the networks and the robustness of the networks. The NNIA (Non-dominated Neighbor Immune Algorithm) is applied to solve the optimization models. We finished simulations of the Barabási-Albert (BA) network and Erdös-Rényi (ER) network. In the solutions, we find the edges that can facilitate the propagation of cascading failure and the edges that can suppress the propagation of cascading failure. From the conclusions, we take optimal protection measures to weaken the damage caused by cascading failures. We also consider actual situations of operational cost feasibility of the edges. People can make a more practical choice based on the operational cost. Our work will be helpful in the design of highly robust networks or improvement of the robustness of networks in the future.

Delusion proneness and 'jumping to conclusions': relative and absolute effects.

PubMed

van der Leer, L; Hartig, B; Goldmanis, M; McKay, R

2015-04-01

That delusional and delusion-prone individuals 'jump to conclusions' is one of the most robust and important findings in the literature on delusions. However, although the notion of 'jumping to conclusions' (JTC) implies gathering insufficient evidence and reaching premature decisions, previous studies have not investigated whether the evidence gathering of delusion-prone individuals is, in fact, suboptimal. The standard JTC effect is a relative effect but using relative comparisons to substantiate absolute claims is problematic. In this study we investigated whether delusion-prone participants jump to conclusions in both a relative and an absolute sense. Healthy participants (n = 112) completed an incentivized probabilistic reasoning task in which correct decisions were rewarded and additional information could be requested for a small price. This combination of rewards and costs generated optimal decision points. Participants also completed measures of delusion proneness, intelligence and risk aversion. Replicating the standard relative finding, we found that delusion proneness significantly predicted task decisions, such that the more delusion prone the participants were, the earlier they decided. This finding was robust when accounting for the effects of risk aversion and intelligence. Importantly, high-delusion-prone participants also decided in advance of an objective rational optimum, gathering fewer data than would have maximized their expected payoff. Surprisingly, we found that even low-delusion-prone participants jumped to conclusions in this absolute sense. Our findings support and clarify the claim that delusion formation is associated with a tendency to 'jump to conclusions'. In short, most people jump to conclusions, but more delusion-prone individuals 'jump further'.

A Rural Implementation of a 52 Node Mixed Wireless Mesh Network in Macha, Zambia

NASA Astrophysics Data System (ADS)

Backens, Jonathan; Mweemba, Gregory; van Stam, Gertjan

In spite of increasing international and academic attention, there remains many challenges facing real world implementations of developing technologies. There has been considerable hype behind Wireless Mesh Networking as the ubiquitous solution for rural ICT in the developing world. In this paper, we present the real world rural mesh network implementation in the village of Macha, Zambia and draw both performance conclusions as well as overall experiential conclusions. The purpose of this paper is to introduce and analyze our low cost solution and extrapolate future trends for rural ICT implementations in Zambia.

MAGNETIC BEHAVIOR OF FUNCTIONALLY MODIFIED SPINEL Ni0.4Ca0.6Fe2O4 NANOFERRITE

NASA Astrophysics Data System (ADS)

Prasad, Arun S.; Dhawan, M. S.; Dolia, S. N.; Samariya, Arvind; Reddy, V. R.; Singhal, R. K.; Predeep, P.

2011-06-01

The editorial board discovered that the data points in several sections of the Mossbauer spectra as given in Figs. 3(a) and 3(b) are exactly identical. This is impossible and nonphysical for the measurement of two different samples (or for that matter not even for the same sample!). The only conclusion we can draw from this figure is that some of the data is fabricated. As a result, the results and conclusions as described in the paper are unacceptable. This article is retracted from its publication in Int. J. Mod. Phys. B.

Television's impact on children.

PubMed

Zuckerman, D M; Zuckerman, B S

1985-02-01

Television has a major impact on children's knowledge, attitudes, and behavior. Research has demonstrated the association between television viewing and four areas: (1) children's aggressive behavior; (2) racial and sex-role stereotypes; (3) decreased interest in reading and school activities; and (4) poorer health habits and attitudes. Methodological limitations make it difficult to draw firm conclusions about a causal relationship between television viewing and children's behavior. Representative studies in these four areas are reviewed, important methodological concerns are pointed out, and conclusions from the research findings are drawn. The implications of the data for pediatricians and other health professionals are discussed.

Evaluation of Robustness to Setup and Range Uncertainties for Head and Neck Patients Treated With Pencil Beam Scanning Proton Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malyapa, Robert; Lowe, Matthew; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester

Purpose: To evaluate the robustness of head and neck plans for treatment with intensity modulated proton therapy to range and setup errors, and to establish robustness parameters for the planning of future head and neck treatments. Methods and Materials: Ten patients previously treated were evaluated in terms of robustness to range and setup errors. Error bar dose distributions were generated for each plan, from which several metrics were extracted and used to define a robustness database of acceptable parameters over all analyzed plans. The patients were treated in sequentially delivered series, and plans were evaluated for both the first seriesmore » and for the combined error over the whole treatment. To demonstrate the application of such a database in the head and neck, for 1 patient, an alternative treatment plan was generated using a simultaneous integrated boost (SIB) approach and plans of differing numbers of fields. Results: The robustness database for the treatment of head and neck patients is presented. In an example case, comparison of single and multiple field plans against the database show clear improvements in robustness by using multiple fields. A comparison of sequentially delivered series and an SIB approach for this patient show both to be of comparable robustness, although the SIB approach shows a slightly greater sensitivity to uncertainties. Conclusions: A robustness database was created for the treatment of head and neck patients with intensity modulated proton therapy based on previous clinical experience. This will allow the identification of future plans that may benefit from alternative planning approaches to improve robustness.« less

Assessment of nerve involvement in the lumbar spine: agreement between magnetic resonance imaging, physical examination and pain drawing findings

PubMed Central

2010-01-01

Background Detection of nerve involvement originating in the spine is a primary concern in the assessment of spine symptoms. Magnetic resonance imaging (MRI) has become the diagnostic method of choice for this detection. However, the agreement between MRI and other diagnostic methods for detecting nerve involvement has not been fully evaluated. The aim of this diagnostic study was to evaluate the agreement between nerve involvement visible in MRI and findings of nerve involvement detected in a structured physical examination and a simplified pain drawing. Methods Sixty-one consecutive patients referred for MRI of the lumbar spine were - without knowledge of MRI findings - assessed for nerve involvement with a simplified pain drawing and a structured physical examination. Agreement between findings was calculated as overall agreement, the p value for McNemar's exact test, specificity, sensitivity, and positive and negative predictive values. Results MRI-visible nerve involvement was significantly less common than, and showed weak agreement with, physical examination and pain drawing findings of nerve involvement in corresponding body segments. In spine segment L4-5, where most findings of nerve involvement were detected, the mean sensitivity of MRI-visible nerve involvement to a positive neurological test in the physical examination ranged from 16-37%. The mean specificity of MRI-visible nerve involvement in the same segment ranged from 61-77%. Positive and negative predictive values of MRI-visible nerve involvement in segment L4-5 ranged from 22-78% and 28-56% respectively. Conclusion In patients with long-standing nerve root symptoms referred for lumbar MRI, MRI-visible nerve involvement significantly underestimates the presence of nerve involvement detected by a physical examination and a pain drawing. A structured physical examination and a simplified pain drawing may reveal that many patients with "MRI-invisible" lumbar symptoms need treatment aimed at nerve involvement. Factors other than present MRI-visible nerve involvement may be responsible for findings of nerve involvement in the physical examination and the pain drawing. PMID:20831785

Effectiveness of Condition-Based Maintenance in Army Aviation

DTIC Science & Technology

2009-06-12

for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data ...sources, gathering and maintaining the data needed, and completing and reviewing this collection of information. Send comments regarding this...increase in efficiency in dollars spent per operational flight hour, the data set was too small to draw major conclusions. Recommendations for

Integration of mental health into primary care in low- and middle-income countries: the PRIME mental healthcare plans.

PubMed

Lund, Crick; Tomlinson, Mark; Patel, Vikram

2016-01-01

This supplement outlines the development and piloting of district mental healthcare plans from five low- and middle-income countries, together with the methods for their design, evaluation and costing. In this editorial we consider the challenges that these programmes face, highlight their innovations and draw conclusions. © The Royal College of Psychiatrists 2016.

[Research on the original plants of Xian Zhao Zi (Senshosi)].

PubMed

Kotaka, Shuji

2008-01-01

Since the Heian period, Xian Zhao Zi (Senshosi) has been used as part of the ceremony believed to help in a healthy pregnancy and safe birth. The purpose of this report is to consider which plants are original Xian Zhao Zi plants. Past research lists certain plants as Xian Zhao Zi, but it was difficult to draw any conclusions.

The Scientific Method Ain't What It Used to Be

ERIC Educational Resources Information Center

Herreid, Clyde Freeman

2010-01-01

Remember the time when all you had to do was memorize these five steps: ask a question, formulate a hypothesis, perform experiment, collect data, and draw conclusions? And you received full credit for defining the scientific method. Well, those days are gone. This article discusses why the "scientific method ain't what it used to be." (Contains 2…

Fostering Interdisciplinary Research in Universities: A Case Study of Leadership, Alignment and Support

ERIC Educational Resources Information Center

Townsend, Tony; Pisapia, John; Razzaq, Jamila

2015-01-01

The aim of this paper is to describe actions designed to foster interdisciplinary research efforts at a major university in the UK. The study employed a descriptive mixed method case study approach to collecting and analysing the data used to draw its conclusions. One hundred and twenty-seven academic staff responded to the survey. The results of…

Civic Education Curriculum Reform in Hong Kong: What Should Be the Direction under Chinese Sovereignty?

ERIC Educational Resources Information Center

Fairbrother, Gregory P.; Kennedy, Kerry J.

2011-01-01

This article uses results from a cross-national analysis of the impact of varying approaches to civic education curriculum delivery on three learning outcomes, to draw conclusions about the value of a government-mandated compulsory, independent subject of civic education in the school curriculum. It starts from the context of Hong Kong, where…

Discovery Lab in the Chemistry Lecture Room: Design and Evaluation of Audio-Visual Constructivist Methodology of Teaching Descriptive Inorganic Chemistry.

ERIC Educational Resources Information Center

Young, Barbara N.; Hoffman, Lyubov

Demonstration of chemical reactions is a tool used in the teaching of inorganic descriptive chemistry to enable students to understand the fundamental concepts of chemistry through the use of concrete examples. For maximum benefit, students need to learn through discovery to observe, interpret, hypothesize, and draw conclusions; however, chemical…

School Districts' Perspectives on the Economic Stimulus Package: School Improvement Grants Present Uncertainty and Opportunity

ERIC Educational Resources Information Center

Scott, Caitlin

2010-01-01

The information in this report is drawn from the responses of a nationally representative sample of school districts to a broader Center on Education Policy (CEP) survey on American Recovery and Reinvestment Act of 2009 (ARRA) administered in the spring of 2010. Survey responses were weighted to draw conclusions for all districts in the 50 states…

Response to Comment on "Water harvesting from air with metal-organic frameworks powered by natural sunlight".

PubMed

Kim, Hyunho; Rao, Sameer R; Kapustin, Eugene A; Narayanan, Shankar; Yang, Sungwoo; Furukawa, Hiroyasu; Umans, Ari S; Yaghi, Omar M; Wang, Evelyn N

2017-11-24

The Comment by Meunier states that the process we described in our report cannot deliver the claimed amount of liquid water in an arid climate. This statement is not valid because the parameters presented in our study were inappropriately combined to draw misguided conclusions. Copyright © 2017, American Association for the Advancement of Science.

Using Artifacts to Understand the Life of a Soldier in World War II

ERIC Educational Resources Information Center

Anson, Staci

2009-01-01

For years, when the author taught about World War II, she used primary and secondary source readings, she presented Power Points, and had her students watch newsreels and other video clips. Today, her students interact with actual artifacts from history so that they can draw conclusions and gain understanding about what the soldiers' lives were…

Hate Speech in Colleges and Universities--The Aftermath of "R.A.V. v. City of St. Paul, Minnesota".

ERIC Educational Resources Information Center

Brown, Valerie L.

1993-01-01

The Supreme Court ruled, in "R.A.V. v. City of St. Paul Minnesota," that the city's Biased-Motivated Crime Ordinance is unconstitutional. Discusses the factual background of "R.A.V.," of "Doe v. University of Michigan," and leading cases in the area of student first amendment rights. Draws conclusions and assesses…

A Systematic Review on Using Literature for the Young Learners in an EFL Classroom

ERIC Educational Resources Information Center

Al-hajji, Badria A.; Shuqair, Khaled M.

2014-01-01

This study has objectives that are exploratory and analytical in nature. It focuses on the use of relevant information with regard to the use of literature in EFL classrooms that is available for an analysis in order to draw conclusions and make useful recommendations. The study is, therefore, conducted as library research using the method of…

Some Decks Are "Better" than Others: The Effect of Reinforcer Type and Task Instructions on Learning in the Iowa Gambling Task

ERIC Educational Resources Information Center

Fernie, Gordon; Tunney, Richard J.

2006-01-01

The Iowa Gambling Task (Bechara, Damasio, Damasio, & Anderson, 1994) has become widely used as a laboratory test of "real-life" decision-making. However, aspects of its administration that have been varied by researchers may differentially affect performance and the conclusions researchers can draw. Some researchers have used facsimile money…

The Public Self: Taking a New Look at Civic Education.

ERIC Educational Resources Information Center

Rettinger, Virginia S.

This paper draws upon research and acquaints the reader with various aspects of the public self--the self interested in political and social issues. The document describes a study of how the public self was discovered. The data produced by this study resulted in the conclusion that to some degree all people have a public self. Most recognize there…

Drawing Conclusions: Confusion between Data and Theory in the Traumatic Memory Debate

ERIC Educational Resources Information Center

Silberg, Joyanna

2003-01-01

This paper examines one of the chief problems in the ongoing debate about the nature and prevalence of the various memory mechanisms that may operate in determining whether a victim/survivor of childhood sexual abuse (CSA) will have delayed recall of the victimization. One of the key problems in the debate about delayed or suppressed memory of…

Why Is a Flower Five-Petaled?

ERIC Educational Resources Information Center

Nishiyama, Yutaka

2004-01-01

This paper examines why many flowers are five-petaled through the use of a five-petaled model that draws insights from the location of cell clusters at a shoot apex, rather than by way of the Fibonacci sequence or the golden ratio as in the past. The conclusion drawn is that flowers are most likely to be five-petaled, followed by six-petaled;…

Pay It Forward: Teacher Candidates' Use of Historical Artifacts to Invigorate K-12 History Instruction

ERIC Educational Resources Information Center

Waring, Scott M.; Torrez, Cheryl; Lipscomb, George

2015-01-01

As advocates of engaging students in historical inquiry and of the use of primary sources to aid in this inquiry, we support the claims of numerous student benefits, such as learning to detect bias, appreciating the interpretive nature of historical thinking, and the drawing of conclusions based on judgments about evidence (Fehn & Koeppen,…

Analysis of habitat-selection rules using an individual-based model

Treesearch

Steven F. Railsback; Bret C. Harvey

2002-01-01

Abstract - Despite their promise for simulating natural complexity,individual-based models (IBMs) are rarely used for ecological research or resource management. Few IBMs have been shown to reproduce realistic patterns of behavior by individual organisms.To test our IBM of stream salmonids and draw conclusions about foraging theory,we analyzed the IBM ’s ability to...

Preliminary ride-quality evaluation of the HM.2 Hoverferry

NASA Technical Reports Server (NTRS)

Mcclurken, E. W., Jr.; Jacobson, I. D.; Kuhlthau, A. R.

1974-01-01

The results of a forty-minute exposure of the HM.2 Hoverferry are presented. Quantitative evaluations were made from aft seats on the starboard side for a sea state considered calm and visually estimated at one-half to one foot. Since this type of craft is sensitive to sea state, the conclusions are based on ideal conditions. Some drawings are included.

Coping with Dying: Lessons That We Should and Should Not Learn from the Work of Elisabeth Kubler-Ross.

ERIC Educational Resources Information Center

Corr, Charles A.

1993-01-01

Appraises work of Elisabeth Kubler-Ross in area of coping with dying. Suggests lessons from that work. Draws broad conclusions about processes involved in coping with dying, argues on behalf of need to develop better theoretical models to explicate what is involved in coping with dying, and suggests requirements for model. (Author/NB)

A Review of Twenty Years of Competency-Based Training in the Australian Vocational Education and Training System

ERIC Educational Resources Information Center

Smith, Erica

2010-01-01

In this paper, the author reflects, both as an academic researcher and as a senior practitioner, on the experience of competency-based training (CBT) in the Australian vocational education and training system. She seeks to draw conclusions about the Australian experience using a typology drawn from the academic literature which focuses on the…

Let's Get beyond Community and Practice: The Many Meanings of Learning by Participating

ERIC Educational Resources Information Center

Edwards, Anne

2005-01-01

This article is an attempt to tease out what is so often termed learning through participation. Drawing on the analysis undertaken by the Learning Outcomes Thematic Group, the use of the participation metaphor in TLRP projects is discussed. The conclusion arrived at is that its use appears mainly to focus on behaviour and engagement in practices.…

Teach Students to Dig for Understanding Using an Unexpected Technological Shovel

ERIC Educational Resources Information Center

Lake, Susan E. L.

2004-01-01

Online genealogy tools is an unexpected resource as these tools not only serve valuable for genealogy research, but also can be used by students to learn about their country's past and learn to use primary materials to draw conclusions. Some of these Online sources like the 1880 census available at www.ancestry.com, www.thepastwhispers.com, which…

Effect of toxic threat nerve agents on anesthetic requirements of representative pr-anesthetic medicants and inhalant and parenteral general anesthetic in the cat. Annual report, 15 July 1985-14 July 1986

DOE Office of Scientific and Technical Information (OSTI.GOV)

Webb, A.I.

1986-07-30

The effect of soman on anesthetic requirements of halothane and isoflurane was studied before and after administration of acepromazine maleate (0.2 mg/kg). Insufficient data has been obtained to date to draw conclusions on any possible drug interactions.

A Statistical Summary of Selected Characteristics of the Student Population of Southwest Texas Junior College.

ERIC Educational Resources Information Center

Southwest Texas Junior Coll., Uvalde.

This report presents statistical data on students at Southwest Texas Junior College in an attempt to provide insight into the characteristics of the student population. The data is presented in tabular form with no effort to draw conclusions or to suggest possible implications. Fall 1974-75 enrollment figures are broken down by class, full-time or…

Can Academic Standards Boost Literacy and Close the Achievement Gap? Policy Brief, Fall 2012

ERIC Educational Resources Information Center

Haskins, Ron; Murnane, Richard; Sawhill, Isabel; Snow, Catherine

2012-01-01

Good jobs in the nation's twenty-first-century economy require advanced literacy skills such as categorizing, evaluating, and drawing conclusions from written texts. The adoption of the Common Core State Standards by nearly all the states, combined with tough literacy assessments that are now in the offing, will soon reveal that literacy skills of…

2012 Minnesota Internet Survey: Digital Divide 2.0 and Beyond

ERIC Educational Resources Information Center

Center for Rural Policy and Development, 2012

2012-01-01

After more than ten years of asking rural Minnesotans about their access to high-speed Internet service, it is possible to draw a few conclusions: (1) It is fairly well accepted now that broadband access has become a necessity for functioning at full capacity in today's world; (2) The digital divide isn't what it used to be; (3) Broadband no…

TOTE Project. A Curriculum Source Book for Teaching Human Relations, Environmental Education, and Camping Skills in the Classroom and on the Trail.

ERIC Educational Resources Information Center

Maughan, Durrell A.; And Others

Backpacking serves as the vehicle for teaching basic secondary school subjects in this curriculum guide which suggests various learning activities for teaching human relations, environmental education, and camping. The activities, some for the classroom and some for the trail, are designed to help students observe, draw conclusions, and develop…

The Date That Lives in Infamy: Pearl Harbor Lesson Plans.

ERIC Educational Resources Information Center

Department of the Navy, Washington, DC.

This lesson plan can help teachers and students understand what happened on December 7, 1941, beginning with the first U.S. treaty with Japan in 1854 through the attacks in 1941. Students use primary sources to synthesize information and draw conclusions about the role of the U.S. Navy in foreign policy and to understand how people in 1941 reacted…

Extending the psycho-historical framework to understand artistic production.

PubMed

Kozbelt, Aaron; Ostrofsky, Justin

2013-04-01

We discuss how the psycho-historical framework can be profitably applied to artistic production, facilitating a synthesis of perception-based and knowledge-based perspectives on realistic observational drawing. We note that artists' technical knowledge itself constitutes a major component of an artwork's historical context, and that links between artistic practice and psychological theory may yet yield conclusions in line with universalist perspectives.

Understanding the physical attractiveness literature: Qualitative reviews versus meta-analysis.

PubMed

Feingold, Alan

2017-01-01

The target article is a qualitative review of selected findings in the physical attractiveness literature. This commentary explains why the meta-analytic approach, frequently used by other attractiveness reviewers, is preferable for drawing unbiased conclusions about the effects of attractiveness. The article's main contribution is affording a foundation for subsequent meta-analysis of the studies discussed in a subjective fashion.

Profile of student critical thinking ability on static fluid concept

NASA Astrophysics Data System (ADS)

Sulasih; Suparmi, A.; Sarwanto

2017-11-01

Critical thinking ability is an important part of educational goals. It has higher complex processes, such as analyzing, synthesizing and evaluating, drawing conclusion and reflection. This study is aimed to know the critical thinking ability of students in learning static fluids of senior high school students. This research uses the descriptive method which its instruments based on the indicator of critical thinking ability developed according to Ennis. The population of this research is XIth grade science class Public Senior High School, SMA N 1, Sambungmacan, Sragen, Central Java. The static fluid teaching material is delivered using Problem Based Learning Model through class experiment. The results of this study shows that the average student of XIth science class have high critical thinking skills, particularly in the ability of providing simple explanation, build basic skill, and provide advanced explanation, but they do not have high enough in ability of drawing conclusion and strategic and tactical components of critical thinking ability in the study of static fluid teaching material. The average of students critical thinking ability is 72.94, with 27,94% of students are in a low category and 72,22% of students in the high category of critical thinking ability.

Content and strategy in syllogistic reasoning.

PubMed

Marrero, Hipólito; Elena, Gámez

2004-09-01

Syllogistic reasoning has been investigated as a general deductive process (Johnson-Laird & Byrne, 1991; Revlis, 1975; Rips, 1994). However, several studies have demonstrated the role of cognitive strategies in this type of reasoning. These strategies focus on the method used by the participants (Ford, 1995; Gilhooly, Logie, Wetherick, & Wynn, 1993) and strategies related to different interpretations of the quantified premises (Roberts, Newstead, & Griggs, 2001). In this paper, we propose that content (as well as individual cognitive differences) is an important factor in inducing a certain strategy or method for syllogistic resolution. Specifically, we suggest that syllogisms with a causal conditional premise that can be extended by an agency premise induce the use of a conditional method. To demonstrate this, we carried out two experiments. Experiment 1 provided evidence that this type of syllogism leads participants to draw the predicted conditional conclusions, in contrast with control content syllogisms. In Experiment 2, we demonstrated that the drawing of conditional conclusions is based on a causal conditional to an agent representation of the syllogism premises. These results support the role of content as inducing a particular strategy for syllogistic resolution. The implications of these results are discussed.

3D robust Chan-Vese model for industrial computed tomography volume data segmentation

NASA Astrophysics Data System (ADS)

Liu, Linghui; Zeng, Li; Luan, Xiao

2013-11-01

Industrial computed tomography (CT) has been widely applied in many areas of non-destructive testing (NDT) and non-destructive evaluation (NDE). In practice, CT volume data to be dealt with may be corrupted by noise. This paper addresses the segmentation of noisy industrial CT volume data. Motivated by the research on the Chan-Vese (CV) model, we present a region-based active contour model that draws upon intensity information in local regions with a controllable scale. In the presence of noise, a local energy is firstly defined according to the intensity difference within a local neighborhood. Then a global energy is defined to integrate local energy with respect to all image points. In a level set formulation, this energy is represented by a variational level set function, where a surface evolution equation is derived for energy minimization. Comparative analysis with the CV model indicates the comparable performance of the 3D robust Chan-Vese (RCV) model. The quantitative evaluation also shows the segmentation accuracy of 3D RCV. In addition, the efficiency of our approach is validated under several types of noise, such as Poisson noise, Gaussian noise, salt-and-pepper noise and speckle noise.

Constructing robust selves after brain injury: positive identity work among members of a female self-help group.

PubMed

Gelech, Jan; Bayly, Melanie; Desjardins, Michel

2017-04-10

Despite common experiences of identity damage, decline, and deterioration, many brain injury survivors succeed in reconstructing robust identities in the wake of injury. Yet, while this accomplishment greatly benefits survivors' quality of life, little is known about how positive identity work might be facilitated or enhanced in therapeutic institutions. Drawing on data from a women's self-help group, we argue that an egalitarian, reflective, strength-focused, and gender-segregated environment can provide female ABI (acquired brain injury) survivors with a fertile scene for identity enhancement and offer unique opportunities for collective identity development. Sociolinguistic interactional analysis revealed four types of positive identity work undertaken within the group: constructing competent selves; tempering the threat of loss and impairment; resisting infantilisation and delegitimisation; and asserting a collective gender identity. This identity work was facilitated by specific programme attributes and activities and contributed to the global project of decentring disability and destigmatising impairments and losses. We call for increased attention to identity issues in brain injury rehabilitation and argue that gender-segregated programming can provide a unique space for female survivors to construct empowering individual and collective identities after injury.

Tongue and hyoid musculature and functional morphology of a neonate gray whale (Cetacea, Mysticeti, Eschrichtius robustus).

PubMed

Kienle, Sarah S; Ekdale, Eric G; Reidenberg, Joy S; Deméré, Tom A

2015-04-01

Little is known about the anatomy and musculature of the gray whale (Eschrichtius robustus), especially related to the anatomy of the tongue and hyoid region. The recovery of an extremely fresh head of a neonatal female gray whale provided an opportunity to conduct the first in-depth investigation of the musculoskeletal features of the tongue and hyoid apparatus. Unlike other mysticetes, the gray whale tongue is strong, muscular, and freely mobile inside the buccal cavity. In particular, the genioglossus and hyoglossus muscles are extremely large and robust making up the majority of the body of the tongue. In addition, the genioglossus had a unique position and fiber orientation in the tongue compared to other mammals. The structure of the hyoid apparatus differs between E. robustus and other mysticete species, although there are similarities among individual elements. We provide the first documentation of fungiform papillae that may be associated with taste buds in Mysticeti. The highly mobile, robust tongue and the presence of well-defined tongue and hyoid musculature are in keeping with observations of gray whale feeding that suggest this group of whales utilize oral suction to draw benthic prey into the buccal cavity. © 2015 Wiley Periodicals, Inc.

Robust synchronization control scheme of a population of nonlinear stochastic synthetic genetic oscillators under intrinsic and extrinsic molecular noise via quorum sensing

PubMed Central

2012-01-01

Background Collective rhythms of gene regulatory networks have been a subject of considerable interest for biologists and theoreticians, in particular the synchronization of dynamic cells mediated by intercellular communication. Synchronization of a population of synthetic genetic oscillators is an important design in practical applications, because such a population distributed over different host cells needs to exploit molecular phenomena simultaneously in order to emerge a biological phenomenon. However, this synchronization may be corrupted by intrinsic kinetic parameter fluctuations and extrinsic environmental molecular noise. Therefore, robust synchronization is an important design topic in nonlinear stochastic coupled synthetic genetic oscillators with intrinsic kinetic parameter fluctuations and extrinsic molecular noise. Results Initially, the condition for robust synchronization of synthetic genetic oscillators was derived based on Hamilton Jacobi inequality (HJI). We found that if the synchronization robustness can confer enough intrinsic robustness to tolerate intrinsic parameter fluctuation and extrinsic robustness to filter the environmental noise, then robust synchronization of coupled synthetic genetic oscillators is guaranteed. If the synchronization robustness of a population of nonlinear stochastic coupled synthetic genetic oscillators distributed over different host cells could not be maintained, then robust synchronization could be enhanced by external control input through quorum sensing molecules. In order to simplify the analysis and design of robust synchronization of nonlinear stochastic synthetic genetic oscillators, the fuzzy interpolation method was employed to interpolate several local linear stochastic coupled systems to approximate the nonlinear stochastic coupled system so that the HJI-based synchronization design problem could be replaced by a simple linear matrix inequality (LMI)-based design problem, which could be solved with the help of LMI toolbox in MATLAB easily. Conclusion If the synchronization robustness criterion, i.e. the synchronization robustness ≥ intrinsic robustness + extrinsic robustness, then the stochastic coupled synthetic oscillators can be robustly synchronized in spite of intrinsic parameter fluctuation and extrinsic noise. If the synchronization robustness criterion is violated, external control scheme by adding inducer can be designed to improve synchronization robustness of coupled synthetic genetic oscillators. The investigated robust synchronization criteria and proposed external control method are useful for a population of coupled synthetic networks with emergent synchronization behavior, especially for multi-cellular, engineered networks. PMID:23101662

R2R - software to speed the depiction of aesthetic consensus RNA secondary structures

PubMed Central

2011-01-01

Background With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these molecules. RNA structural diagrams are typically made either with general-purpose drawing programs like Adobe Illustrator, or with automated or interactive programs specific to RNA. Unfortunately, the use of applications like Illustrator is extremely time consuming, while existing RNA-specific programs produce figures that are useful, but usually not of the same aesthetic quality as those produced at great cost in Illustrator. Additionally, most existing RNA-specific applications are designed for drawing single RNA molecules, not consensus diagrams. Results We created R2R, a computer program that facilitates the generation of aesthetic and readable drawings of RNA consensus diagrams in a fraction of the time required with general-purpose drawing programs. Since the inference of a consensus RNA structure typically requires a multiple-sequence alignment, the R2R user annotates the alignment with commands directing the layout and annotation of the RNA. R2R creates SVG or PDF output that can be imported into Adobe Illustrator, Inkscape or CorelDRAW. R2R can be used to create consensus sequence and secondary structure models for novel RNA structures or to revise models when new representatives for known RNA classes become available. Although R2R does not currently have a graphical user interface, it has proven useful in our efforts to create 100 schematic models of distinct noncoding RNA classes. Conclusions R2R makes it possible to obtain high-quality drawings of the consensus sequence and structural models of many diverse RNA structures with a more practical amount of effort. R2R software is available at http://breaker.research.yale.edu/R2R and as an Additional file. PMID:21205310

How children remember neutral and emotional pictures: boundary extension in children's scene memories.

PubMed

Candel, Ingrid; Merckelbach, Harald; Houben, Katrijn; Vandyck, Inne

2004-01-01

Boundary extension is the tendency to remember more of a scene than was actually shown. The dominant interpretation of this memory illusion is that it originates from schemata that people construct when viewing a scene. Evidence of boundary extension has been obtained primarily with adult participants who remember neutral pictures. The current study addressed the developmental stability of this phenomenon. Therefore, we investigated whether children aged 10-12 years display boundary extension for neutral pictures. Moreover, we examined emotional scene memory. Eighty-seven children drew pictures from memory after they had seen either neutral or emotional pictures. Both their neutral and emotional drawings revealed boundary extension. Apparently, the schema construction that underlies boundary extension is a robust and ubiquitous process.

Family and Teacher Characteristics as Predictors of Parent Involvement in Education During Early Childhood Among Afro-Caribbean and Latino Immigrant Families

PubMed Central

Calzada, Esther J.; Huang, Keng-Yen; Hernandez, Miguel; Soriano, Erika; Acra, C. Francoise; Dawson-McClure, Spring; Kamboukos, Dimitra; Brotman, Laurie

2015-01-01

Parent involvement is a robust predictor of academic achievement, but little is known about school- and home-based involvement in immigrant families. Drawing on ecological theories, the present study examined contextual characteristics as predictors of parent involvement among Afro-Caribbean and Latino parents of young students in urban public schools. Socioeconomic disadvantage was associated with lower home-based involvement. Several factors were associated with higher involvement, including parents’ connection to their culture of origin and to U.S. culture, engagement practices by teachers and parent–teacher ethnic consonance (for Latinos only). Findings have implications for promoting involvement among immigrant families of students in urban schools. PMID:26417116

Adaptive infrared-reflecting systems inspired by cephalopods

NASA Astrophysics Data System (ADS)

Xu, Chengyi; Stiubianu, George T.; Gorodetsky, Alon A.

2018-03-01

Materials and systems that statically reflect radiation in the infrared region of the electromagnetic spectrum underpin the performance of many entrenched technologies, including building insulation, energy-conserving windows, spacecraft components, electronics shielding, container packaging, protective clothing, and camouflage platforms. The development of their adaptive variants, in which the infrared-reflecting properties dynamically change in response to external stimuli, has emerged as an important unmet scientific challenge. By drawing inspiration from cephalopod skin, we developed adaptive infrared-reflecting platforms that feature a simple actuation mechanism, low working temperature, tunable spectral range, weak angular dependence, fast response, stability to repeated cycling, amenability to patterning and multiplexing, autonomous operation, robust mechanical properties, and straightforward manufacturability. Our findings may open opportunities for infrared camouflage and other technologies that regulate infrared radiation.

Structural and robustness properties of smart-city transportation networks

NASA Astrophysics Data System (ADS)

Zhang, Zhen-Gang; Ding, Zhuo; Fan, Jing-Fang; Meng, Jun; Ding, Yi-Min; Ye, Fang-Fu; Chen, Xiao-Song

2015-09-01

The concept of smart city gives an excellent resolution to construct and develop modern cities, and also demands infrastructure construction. How to build a safe, stable, and highly efficient public transportation system becomes an important topic in the process of city construction. In this work, we study the structural and robustness properties of transportation networks and their sub-networks. We introduce a complementary network model to study the relevance and complementarity between bus network and subway network. Our numerical results show that the mutual supplement of networks can improve the network robustness. This conclusion provides a theoretical basis for the construction of public traffic networks, and it also supports reasonable operation of managing smart cities. Project supported by the Major Projects of the China National Social Science Fund (Grant No. 11 & ZD154).

Robustness against parametric noise of nonideal holonomic gates

NASA Astrophysics Data System (ADS)

Lupo, Cosmo; Aniello, Paolo; Napolitano, Mario; Florio, Giuseppe

2007-07-01

Holonomic gates for quantum computation are commonly considered to be robust against certain kinds of parametric noise, the cause of this robustness being the geometric character of the transformation achieved in the adiabatic limit. On the other hand, the effects of decoherence are expected to become more and more relevant when the adiabatic limit is approached. Starting from the system described by Florio [Phys. Rev. A 73, 022327 (2006)], here we discuss the behavior of nonideal holonomic gates at finite operational time, i.e., long before the adiabatic limit is reached. We have considered several models of parametric noise and studied the robustness of finite-time gates. The results obtained suggest that the finite-time gates present some effects of cancellation of the perturbations introduced by the noise which mimic the geometrical cancellation effect of standard holonomic gates. Nevertheless, a careful analysis of the results leads to the conclusion that these effects are related to a dynamical instead of a geometrical feature.

A Capability-Based Approach to Analyzing the Effectiveness and Robustness of an Offshore Patrol Vessel in the Search and Rescue Mission

DTIC Science & Technology

2012-12-01

13 D. NPSS MODEL DEVELOPMENT...COMPARISON: NPSS MODEL WITH ITALIAN MODEL ...................51 IV. CONCLUSIONS AND RECOMMENDATIONS...58 1. Italian Model Recommendations ......................................................58 2. NPSS Model

Comparing hospital costs: what is gained by accounting for more than a case-mix index?

PubMed

Hvenegaard, Anne; Street, Andrew; Sørensen, Torben Højmark; Gyrd-Hansen, Dorte

2009-08-01

We explore what effect controlling for various patient characteristics beyond a case-mix index (DRG) has on inferences drawn about the relative cost performance of hospital departments. We estimate fixed effect cost models in which 3754 patients are clustered within six Danish vascular departments. We compare a basic model including a DRG index only with models also including age and gender, health related characteristics, such as smoking status, diabetes, and American Society of Anesthesiogists score (ASA-score), and socioeconomic characteristics such as income, employment and whether the patient lives alone. We find that the DRG index is a robust and important explanatory factor and adding other routinely collected characteristics such as age and gender and other health related or socioeconomic characteristics do not seem to alter the results significantly. The results are more sensitive to choice of functional form, i.e. in particular to whether costs are log transformed. Our results suggest that the routinely collected characteristics such as DRG index, age and gender are sufficient when drawing inferences about relative cost performance. Adding health related or socioeconomic patient characteristics only slightly improves our model in terms of explanatory power but not when drawing inferences about relative performance. The results are, however, sensitive to whether costs are log transformed.

2016 Summer Series - Ophir Frieder - Searching Harsh Environments

NASA Image and Video Library

2016-07-12

Analysis of selective data that fits our investigative tool may lead to erroneous or limited conclusions. The universe consists of multi states and our recording of them adds complexity. By finding methods to increase the robustness of our digital data collection and applying likely relationship search methods that can handle all the data, we will increase the resolution of our conclusions. Frieder will present methods to increase our ability to capture and search digital data.

Combined Training Enhances Skeletal Muscle Mitochondrial Oxidative Capacity Independent of Age

PubMed Central

Lanza, Ian R.; Henderson, Gregory C.; Rao, Rajesh R.; Spiegelman, Bruce M.

2015-01-01

Context: Skeletal muscle from sedentary older adults exhibits reduced mitochondrial abundance and oxidative capacity. Objective: The primary objective was to determine whether 8 weeks of combined training (CT) has a more robust effect than endurance training (ET) or resistance training (RT) on mitochondrial physiology in healthy young (18–30 years) and older (≥65 years) adults. Intervention: Thirty-four young and 31 older adults were randomly assigned to 8 weeks of ET, RT, and control/CT. Control subjects completed 8 weeks of no exercise (control) followed by 8 weeks of CT. Body composition, skeletal muscle strength, and peak oxygen uptake were measured before and after the intervention. Vastus lateralis muscle biopsy samples were obtained before and 48 hours after the intervention. Mitochondrial physiology was evaluated by high-resolution respirometry and expression of mitochondrial proteins and transcription factors by quantitative PCR and immunoblotting. Results: ET and CT significantly increased oxidative capacity and expression of mitochondrial proteins and transcription factors. All training modalities improved body composition, cardiorespiratory fitness, and skeletal muscle strength. CT induced the most robust improvements in mitochondria-related outcomes and physical characteristics despite lower training volumes for the ET and RT components. Importantly, most of the adaptations to training occurred independent of age. Conclusion: Collectively, these results demonstrate that both ET and CT increase muscle mitochondrial abundance and capacity although CT induced the most robust improvements in the outcomes measured. In conclusion, CT provides a robust exercise regimen to improve muscle mitochondrial outcomes and physical characteristics independent of age. PMID:25599385

An overview of the impact of rare disease characteristics on research methodology.

PubMed

Whicher, Danielle; Philbin, Sarah; Aronson, Naomi

2018-01-19

About 30 million individuals in the United States are living with a rare disease, which by definition have a prevalence of 200,000 or fewer cases in the United States ([National Organization for Rare Disorders], [About NORD], [2016]). Disease heterogeneity and geographic dispersion add to the difficulty of completing robust studies in small populations. Improving the ability to conduct research on rare diseases would have a significant impact on population health. The purpose of this paper is to raise awareness of methodological approaches that can address the challenges to conducting robust research on rare diseases. We conducted a landscape review of available methodological and analytic approaches to address the challenges of rare disease research. Our objectives were to: 1. identify algorithms for matching study design to rare disease attributes and the methodological approaches applicable to these algorithms; 2. draw inferences on how research communities and infrastructure can contribute to the efficiency of research on rare diseases; and 3. to describe methodological approaches in the rare disease portfolio of the Patient-Centered Outcomes Research Institute (PCORI), a funder promoting both rare disease research and research infrastructure. We identified three algorithms for matching study design to rare disease or intervention characteristics (Gagne, et.al, BMJ 349:g6802, 2014); (Gupta, et.al, J Clin Epidemiol 64:1085-1094, 2011); (Cornu, et. al, Orphet J Rare Dis 8:48,2012) and summarized the applicable methodological and analytic approaches. From this literature we were also able to draw inferences on how an effective research infrastructure can set an agenda, prioritize studies, accelerate accrual, catalyze patient engagement and terminate poorly performing studies. Of the 24 rare disease projects in the PCORI portfolio, 11 are randomized controlled trials (RCTs) using standard designs. Thirteen are observational studies using case-control, prospective cohort, or natural history designs. PCORI has supported the development of 9 Patient-Powered Research Networks (PPRNs) focused on rare diseases. Matching research design to attributes of rare diseases and interventions can facilitate the completion of RCTs that are adequately powered. An effective research infrastructure can improve efficiency and avoid waste in rare disease research. Our review of the PCORI research portfolio demonstrates that it is feasible to conduct RCTs in rare disease. However, most of these studies are using standard RCT designs. This suggests that use of a broader array of methodological approaches to RCTs --such as adaptive trials, cross-over trials, and early escape designs can improve the productivity of robust research in rare diseases.

The comparison between several robust ridge regression estimators in the presence of multicollinearity and multiple outliers

NASA Astrophysics Data System (ADS)

Zahari, Siti Meriam; Ramli, Norazan Mohamed; Moktar, Balkiah; Zainol, Mohammad Said

2014-09-01

In the presence of multicollinearity and multiple outliers, statistical inference of linear regression model using ordinary least squares (OLS) estimators would be severely affected and produces misleading results. To overcome this, many approaches have been investigated. These include robust methods which were reported to be less sensitive to the presence of outliers. In addition, ridge regression technique was employed to tackle multicollinearity problem. In order to mitigate both problems, a combination of ridge regression and robust methods was discussed in this study. The superiority of this approach was examined when simultaneous presence of multicollinearity and multiple outliers occurred in multiple linear regression. This study aimed to look at the performance of several well-known robust estimators; M, MM, RIDGE and robust ridge regression estimators, namely Weighted Ridge M-estimator (WRM), Weighted Ridge MM (WRMM), Ridge MM (RMM), in such a situation. Results of the study showed that in the presence of simultaneous multicollinearity and multiple outliers (in both x and y-direction), the RMM and RIDGE are more or less similar in terms of superiority over the other estimators, regardless of the number of observation, level of collinearity and percentage of outliers used. However, when outliers occurred in only single direction (y-direction), the WRMM estimator is the most superior among the robust ridge regression estimators, by producing the least variance. In conclusion, the robust ridge regression is the best alternative as compared to robust and conventional least squares estimators when dealing with simultaneous presence of multicollinearity and outliers.

About Cats and Dogs...Reconsidering the Relationship between Pet Ownership and Health Related Outcomes in Community-Dwelling Elderly

ERIC Educational Resources Information Center

Rijken, Mieke; van Beek, Sandra

2011-01-01

Having a pet has been claimed to have beneficial health effects, but methodologically sound empirical studies are scarce. Small sample sizes and a lack of information about the specific type of pets involved make it difficult to draw unambiguous conclusions. We aimed to shed light on the relationship between pet ownership and several health…

Characterization of 81P/Wild 2 Particles C2067,1,111,6.0 and C2067,1,111,8.0

NASA Technical Reports Server (NTRS)

Smith, T.; Khodja, H.; Raepsaet, C.; Burchell, M. J.; Flynn, G. J.; Herzog, G. F.; Park, J.; Lindsay, F.; Nakamura-Messenger, K.; Keller, L. P.;

Pulmonary Stress Induced by Hyperthermia: Role of Airway Sensory Nerves

DTIC Science & Technology

2013-10-01

ABSTRACT Based upon the results obtained from these studies, we can draw the following conclusions: 1) Airway hyperresponsiveness developed in Ova ...hyperthermia in Ova -sensitized rats. The manuscript reporting the results obtained frim this study has been accepted for publication by the Journal of...to increasing airway temperature. Our results showed: 1) In Brown-Norway rats actively sensitized by ovalbumin ( Ova ), isocapnic hyperventilation with

Mechanisms of Mitochondrial Dysfunction in Autism

DTIC Science & Technology

2012-07-01

area code) Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std. Z39.18 Mechanisms of Mitochondrial Dysfunction in Autism Dr. John Shoffner...before we will be able to draw meaningful conclusions from this study. Autism , functional MRI, mitochondria, mitochondrial disease 15 Table of Contents...mitochondrial defects in autism are not known, it is hypothesized that significant numbers of individuals with autism and autistic spectrum disorders

Comment on "Benefits of completing homework for students with different aptitudes in an introductory electricity and magnetism course"

NASA Astrophysics Data System (ADS)

Rieger, G. W.; Reinsberg, S. A.; Wieman, C. E.

2016-12-01

We present a comment on "Benefits of completing homework for students with different aptitudes in an introductory electricity and magnetism course", by F. J. Kontur, K. de La Harpe, and N. B. Terry PRST-PER 11, 010105 (2015). Our data show that the conclusions Kontur and coworkers draw from their data may not be generally applicable.

Comment on "Benefits of Completing Homework for Students with Different Aptitudes in an Introductory Electricity and Magnetism Course"

ERIC Educational Resources Information Center

Rieger, G. W.; Reinsberg, S. A.; Wieman, C. E.

2016-01-01

We present a comment on "Benefits of completing homework for students with different aptitudes in an introductory electricity and magnetism course", by F. J. Kontur, K. de La Harpe, and N. B. Terry PRST-PER 11, 010105 (2015). Our data show that the conclusions Kontur and coworkers draw from their data may not be generally applicable.

Ownership Patterns of Natural Resources in Rural America: Implications for Distribution of Wealth and Income. Rural Development, Poverty, and Natural Resources Workshop Paper Series, Part IV.

ERIC Educational Resources Information Center

Clawson, Marion

Beginning with definitions of land ownership and natural resources, this paper traces United States resource ownership patterns and draws conclusions for rural areas. Following the definitions, a general history of resource ownership discusses disposition of land from government to private owner, noting that the cadastral survey system still in…

Assessment of SEPS solar array technology for orbital service module application

NASA Technical Reports Server (NTRS)

1978-01-01

Work performed in the following assessment areas on the SEPS solar array is reported: (1) requirements definition, (2) electrical design evaluation, (3) mechanical design evaluation, and (4) design modification analysis. General overall assessment conclusions are summarized. There are no known serious design limitations involved in the implementation of the recommended design modifications. A section of orbiter and array engineering drawings is included.

Blast and Fragment Protective Sandwich Panel Concepts for Stainless Steel Monohull Designs

DTIC Science & Technology

2008-10-21

to draw broader conclusions. 8. Concluding remarks The resistance of metallic sandwich panels to localized spherical impulsive sources has been...hour per response, including the time for reviewing instructions, searching existing data sources , gathering and maintaining the data needed, and...applications and ship hull blister attachments. Technical Approach The approach used in this research program exploited progress made in metallic

US Army Organizational Culture’s Effect on Innovation and Creativity

DTIC Science & Technology

2017-05-25

of high levels of hierarchical control, clearly defined roles, and centralized decision-making impede flexibility and creativity. When innovation is...of thinking people experience when they are deeply involved in a cohesive team. Members of cohesive decision...represent C.J. Jung’s basic theory on psychological types. In general, these preferences affect what people attend to and how they draw conclusions about

Unanimous Constitutional Consent and the Immigration Problem

DTIC Science & Technology

2004-12-01

Wolf, EU-Erweiterung: Anmerkungen zum Balassa - Samuelson -Effekt, Nr. 3/2002, erschienen in: Stefan Reitz (Hg.): Theoretische und wirtschafispolitische...the individualistic norm. Their main argument is that the contradiction between collective coercion and individual freedom cannot be dissolved at the... arguments against this way of reasoning for there usually will be holes in that veil, so that it may be possible to draw conclusions from the past with

Methods and Strategies: Beyond the Textbook--But Not Just "Hands On". Using High-Quality Informational Texts to Meet the "Next Generation Science Standards"

ERIC Educational Resources Information Center

Vick, Matthew

2016-01-01

Science teaching continues to move away from teaching science as merely a body of facts and figures to be memorized to a process of exploring and drawing conclusions. The Next Generation Science Standards (NGSS) emphasize eight science and engineering practices that ask students to apply scientific and engineering reasoning and explanation. This…

The Relation between Child Maltreatment and Adolescent Suicidal Behavior: A Systematic Review and Critical Examination of the Literature

ERIC Educational Resources Information Center

Miller, Adam B.; Esposito-Smythers, Christianne; Weismoore, Julie T.; Renshaw, Keith D.

2013-01-01

A large body of research suggests that child maltreatment (CM) is associated with adolescent suicidal ideation and attempts. These studies, however, have not been critically examined and summarized in a manner that allows us to draw firm conclusions and make recommendations for future research and clinical work in this area. In this review, we…

Web 2.0 and the Impact of ICT Fuelled Participatory Culture in Rural and Remote Education: (SPERA Keynote 2009 Conference Address)

ERIC Educational Resources Information Center

Anderson, Neil

2009-01-01

This paper and presentation reviews the collective opinion of key Australian researchers concerning the emerging technologies most likely to have a significant impact on learning and teaching in regional, rural and remote areas. It then draws on the conclusions of the Horizon Report (2008) concerning key ICT drivers likely to influence…

The Psychometric Properties of the Socio-Moral Reflection Measure-Short Form and the Moral Theme Inventory for Men with and without Intellectual Disabilities

ERIC Educational Resources Information Center

Langdon, Peter E.; Murphy, Glynis H.; Clare, Isabel C. H.; Palmer, Emma J.

2010-01-01

Drawing conclusions from the literature regarding the moral development of people with intellectual disabilities (IDs) is difficult because of the use of unstandardised and idiosyncratic measures. In order to address this short-coming, a moral reasoning production measure (the Socio-Moral Reflection Measure-Short Form; SRM-SF) and a recognition…

A Study of the Organizational Culture at a Higher Education Institution [Case Study: Plekhanov Russian University of Economics (PRUE)

ERIC Educational Resources Information Center

Vasyakin, Bogdan S.; Ivleva, Marina I.; Pozharskaya, Yelena L.; Shcherbakova, Olga I.

2016-01-01

The article offers an analysis of the organizational culture at a higher education institution as in the case of the Plekhanov Russian University of Economics, conducted in order to study the students' involvement in this culture and to draw conclusions as to what organizational culture principles are internalized by the students. The study used…

Geometric Comparisons of Selected Small Topographically Fresh Volcanoes in the Borealis and Elysium Planitia Volcanic Fields, Mars: Implications for Eruptive Styles

NASA Technical Reports Server (NTRS)

Taylor, K.; Sakimoto, S. E. H.; Mitchell, D.

2002-01-01

MOLA (Mars Orbiter Laser Altimeter) data from small, topographically fresh volcanoes from the Elysium and Borealis regions were gridded and analyzed using GMT (Generic Mapping Tools) programs. Results compare eruptive styles of the two regions, and draw conclusions about the different volcanic regions. Additional information is contained in the original extended abstract.

Application of the new Cross Recurrence Plots to multivariate data

NASA Astrophysics Data System (ADS)

Thiel, M.; Romano, C.; Kurths, J.

2003-04-01

We extend and then apply the method of the new Cross Recurrence Plots (XRPs) to multivariate data. After introducing the new method we carry out an analysis of spatiotemporal ecological data. We compute not only the Rényi entropies and cross entropies by XRP, that allow to draw conclusions about the coupling of the systems, but also find a prediction horizon for intermediate time scales.

Lessons Learned from FIPSE Projects: 15 Directors of Reform Projects in Postsecondary Education Draw Conclusions about What Worked, What Didn't, and Why.

ERIC Educational Resources Information Center

Marcus, Dora, Ed.

This monograph describes what worked and what did not in 15 college and university programs sponsored by the Fund for the Improvement of Postsecondary Education from 1984 to 1987. Each description includes information on the project's purpose, innovative features, evaluation, impact or changes from the grant activities, what worked unexpectedly,…

Omega 3 polyunsaturated fatty acids and body weight.

PubMed

Martínez-Victoria, Emilio; Yago, María Dolores

2012-06-01

In animal studies, n-3 PUFA have been shown to influence body composition and to reduce the accumulation of body fat, thereby affecting body weight homeostasis. In addition, it has been suggested that an additional supply of n-3 PUFA during pregnancy or lactation, or both, would have a beneficial effect on birth weight and infant growth and development. The purpose of the present study was to systematically review interventional clinical trials on the effects of dietary n-3 PUFA supplementation on body weight in adult subjects and in infants whose mothers were supplemented with these fatty acids during pregnancy and/or lactation. A systematic search, focused on n-3 PUFA and body weight, and limited to controlled clinical trials, was performed in different databases. The quality of all included studies was assessed against set criteria, and results of eligible trials were compared. There were few studies targeting this topic. In adults, all of the five studies included, except for one, show no change in body weight by dietary supplementation with n-3 PUFA. Within those trials conducted in pregnant and/or lactating women in which a main outcome was birth weight or growth in infancy, two showed a modest increase in birth weight and the rest showed no effect. None of the trials showed an effect of maternal n-3 PUFA supplementation on infant's weight at the short term. However, it should be noted that a number of limitations, including a variety of experimental designs, type and doses of n-3 PUFA, and high attrition rates, among others, make impossible to draw robust conclusions from this review.

Alcohol Screening and Brief Intervention in Workplace Settings and Social Services: A Comparison of Literature

PubMed Central

Schulte, Bernd; O’Donnell, Amy Jane; Kastner, Sinja; Schmidt, Christiane Sybille; Schäfer, Ingo; Reimer, Jens

2014-01-01

Background: The robust evidence base for the effectiveness of alcohol screening and brief interventions (ASBIs) in primary health care (PHC) suggests that a widespread expansion of ASBI in non-medical settings could be beneficial. Social service and criminal justice settings work frequently with persons with alcohol use disorders, and workplace settings can be an appropriate setting for the implementation of alcohol prevention programs, as a considerable part of their social interactions takes place in this context. Methods: Update of two systematic reviews on ASBI effectiveness in workplaces, social service, and criminal justice settings. Review to identify implementation barriers and facilitators and future research needs of ASBI in non-medical settings. Results: We found a limited number of randomized controlled trials in non-medical settings with an equivocal evidence of effectiveness of ASBI. In terms of barriers and facilitators to implementation, the heterogeneity of non-medical settings makes it challenging to draw overarching conclusions. In the workplace, employee concerns with regard to the consequences of self-disclosure appear to be key. For social services, the complexity of certain client needs suggest that a stepped and carefully tailored approach is likely to be required. Discussion: Compared to PHC, the reviewed settings are far more heterogeneous in terms of client groups, external conditions, and the focus on substance use disorders. Thus, future research should try to systematize these differences, and consider their implications for the deliverability, acceptance, and potential effectiveness of ASBI for different target groups, organizational frameworks, and professionals. PMID:25339914

Diffusion-Welded Microchannel Heat Exchanger for Industrial Processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piyush Sabharwall; Denis E. Clark; Michael V. Glazoff

The goal of next generation reactors is to increase energy ef?ciency in the production of electricity and provide high-temperature heat for industrial processes. The ef?cient transfer of energy for industrial applications depends on the ability to incorporate effective heat exchangers between the nuclear heat transport system and the industrial process. The need for ef?ciency, compactness, and safety challenge the boundaries of existing heat exchanger technology. Various studies have been performed in attempts to update the secondary heat exchanger that is downstream of the primary heat exchanger, mostly because its performance is strongly tied to the ability to employ more ef?cientmore » industrial processes. Modern compact heat exchangers can provide high compactness, a measure of the ratio of surface area-to-volume of a heat exchange. The microchannel heat exchanger studied here is a plate-type, robust heat exchanger that combines compactness, low pressure drop, high effectiveness, and the ability to operate with a very large pressure differential between hot and cold sides. The plates are etched and thereafter joined by diffusion welding, resulting in extremely strong all-metal heat exchanger cores. After bonding, any number of core blocks can be welded together to provide the required ?ow capacity. This study explores the microchannel heat exchanger and draws conclusions about diffusion welding/bonding for joining heat exchanger plates, with both experimental and computational modeling, along with existing challenges and gaps. Also, presented is a thermal design method for determining overall design speci?cations for a microchannel printed circuit heat exchanger for both supercritical (24 MPa) and subcritical (17 MPa) Rankine power cycles.« less

Isoprenoid emission variation of Norway spruce across a European latitudinal transect

NASA Astrophysics Data System (ADS)

van Meeningen, Ylva; Wang, Min; Karlsson, Tomas; Seifert, Ana; Schurgers, Guy; Rinnan, Riikka; Holst, Thomas

2017-12-01

Norway spruce (Picea abies) is one of the dominant tree species in the European boreal zone with the capacity to grow over large areas within Europe. It is an important emitter of biogenic volatile organic compounds (BVOCs), which can act as precursors of photochemical smog and ozone and contribute to the formation and growth of secondary organic aerosols (SOA) in the atmosphere. Isoprenoid emissions were measured from Norway spruce trees at seven different sites, distributed from Ljubljana in Slovenia to Piikkiö in Finland. Four of the sites were part of a network of genetically identical spruce trees and contained two separate provenances. The remaining three sites were part of other networks which have been used to conduct studies in the European boreal zone. There were minimal differences in the standardized emission rates between sites and across latitudes. The emission profile differed between provenances and sites, but there were not any distinct patterns which could be connected to a change in latitude. By using genetically identical trees and comparing the emission rates between sites and with genetically different trees, it was observed that the emission patterns were mostly influenced by genetics. But in order to confirm this possible stability of the relative emission profile based on genetics, more studies need to be performed. The effects of branch height, season and variation between years on observed emission pattern variations were also investigated. There were indications of potential influences of all three factors. However, due to different experimental setups between measurement campaigns, it is difficult to draw any robust conclusions.

Data-Limited Population-Status Evaluation of Two Coastal Fishes in Southern Angola Using Recreational Catch Length-Frequency Data

PubMed Central

Beckensteiner, Jennifer; Kaplan, David M.; Potts, Warren M.; Santos, Carmen V.; O’Farrell, Michael R.

2016-01-01

Excessive truncation of a population’s size structure is often identified as an important deleterious effect of exploitation, yet the effect on population persistence of size-structure truncation caused by exploitation is often not quantified due to data limitations. In this study, we estimate changes in eggs per recruit (EPR) using annual length-frequency samples over a 9 year period to assess persistence of the two most important recreational fishes in southern Angola: west coast dusky kob (Argyrosomus coronus) and leerfish (Lichia amia). Using a length- and age-structured model, we improve on an existing method to fit this type of model to length-frequency data and estimate EPR. The objectives of the methodological changes are to add flexibility and robustness to the approach for assessing population status in data-limited situations. Results indicate that dusky kob presents very low levels of EPR (5%-10% of the per recruit reproductive capacity in the absence of fishing) in 2013, whereas large inter-annual variability in leerfish estimates suggest caution must be applied when drawing conclusions about its exploitation status. Using simulated length frequency data with known parameter values, we demonstrate that recruitment decline due to overexploitation leads to overestimation of EPR values. Considering the low levels of EPR estimated for the study species, recruitment limitation is not impossible and true EPR values may be even lower than our estimates. It is, therefore, likely that management action, such as the creation of Marine Protected Areas, is needed to reconstitute the west coast dusky kob population. PMID:26829489

Supplier-induced demand: re-examining identification and misspecification in cross-sectional analysis.

PubMed

Peacock, Stuart J; Richardson, Jeffrey R J

2007-09-01

This paper re-examines criticisms of cross-sectional methods used to test for supplier-induced demand (SID) and re-evaluates the empirical evidence using data from Australian medical services. Cross-sectional studies of SID have been criticised on two grounds. First, and most important, the inclusion of the doctor supply in the demand equation leads to an identification problem. This criticism is shown to be invalid, as the doctor supply variable is stochastic and depends upon a variety of other variables including the desirability of the location. Second, cross-sectional studies of SID fail diagnostic tests and produce artefactual findings due to model misspecification. Contrary to this, the re-evaluation of cross-sectional Australian data indicate that demand equations that do not include the doctor supply are misspecified. Empirical evidence from the re-evaluation of Australian medical services data supports the notion of SID. Demand and supply equations are well specified and have very good explanatory power. The demand equation is identified and the desirability of a location is an important predictor of the doctor supply. Results show an average price elasticity of demand of 0.22 and an average elasticity of demand with respect to the doctor supply of 0.46, with the impact of SID becoming stronger as the doctor supply rises. The conclusion we draw from this paper is that two of the main criticisms of the empirical evidence supporting the SID hypothesis have been inappropriately levelled at the methods used. More importantly, SID provides a satisfactory, and robust, explanation of the empirical data on the demand for medical services in Australia.

Long-term eclipse timing of white dwarf binaries: an observational hint of a magnetic mechanism at work

NASA Astrophysics Data System (ADS)

Bours, M. C. P.; Marsh, T. R.; Parsons, S. G.; Dhillon, V. S.; Ashley, R. P.; Bento, J. P.; Breedt, E.; Butterley, T.; Caceres, C.; Chote, P.; Copperwheat, C. M.; Hardy, L. K.; Hermes, J. J.; Irawati, P.; Kerry, P.; Kilkenny, D.; Littlefair, S. P.; McAllister, M. J.; Rattanasoon, S.; Sahman, D. I.; Vučković, M.; Wilson, R. W.

2016-08-01

We present a long-term programme for timing the eclipses of white dwarfs in close binaries to measure apparent and/or real variations in their orbital periods. Our programme includes 67 close binaries, both detached and semi-detached and with M-dwarfs, K-dwarfs, brown dwarfs or white dwarfs secondaries. In total, we have observed more than 650 white dwarf eclipses. We use this sample to search for orbital period variations and aim to identify the underlying cause of these variations. We find that the probability of observing orbital period variations increases significantly with the observational baseline. In particular, all binaries with baselines exceeding 10 yr, with secondaries of spectral type K2 - M5.5, show variations in the eclipse arrival times that in most cases amount to several minutes. In addition, among those with baselines shorter than 10 yr, binaries with late spectral type (>M6), brown dwarf or white dwarf secondaries appear to show no orbital period variations. This is in agreement with the so-called Applegate mechanism, which proposes that magnetic cycles in the secondary stars can drive variability in the binary orbits. We also present new eclipse times of NN Ser, which are still compatible with the previously published circumbinary planetary system model, although only with the addition of a quadratic term to the ephemeris. Finally, we conclude that we are limited by the relatively short observational baseline for many of the binaries in the eclipse timing programme, and therefore cannot yet draw robust conclusions about the cause of orbital period variations in evolved, white dwarf binaries.

Data-Limited Population-Status Evaluation of Two Coastal Fishes in Southern Angola Using Recreational Catch Length-Frequency Data.

PubMed

Beckensteiner, Jennifer; Kaplan, David M; Potts, Warren M; Santos, Carmen V; O'Farrell, Michael R

2016-01-01

Excessive truncation of a population's size structure is often identified as an important deleterious effect of exploitation, yet the effect on population persistence of size-structure truncation caused by exploitation is often not quantified due to data limitations. In this study, we estimate changes in eggs per recruit (EPR) using annual length-frequency samples over a 9 year period to assess persistence of the two most important recreational fishes in southern Angola: west coast dusky kob (Argyrosomus coronus) and leerfish (Lichia amia). Using a length- and age-structured model, we improve on an existing method to fit this type of model to length-frequency data and estimate EPR. The objectives of the methodological changes are to add flexibility and robustness to the approach for assessing population status in data-limited situations. Results indicate that dusky kob presents very low levels of EPR (5%-10% of the per recruit reproductive capacity in the absence of fishing) in 2013, whereas large inter-annual variability in leerfish estimates suggest caution must be applied when drawing conclusions about its exploitation status. Using simulated length frequency data with known parameter values, we demonstrate that recruitment decline due to overexploitation leads to overestimation of EPR values. Considering the low levels of EPR estimated for the study species, recruitment limitation is not impossible and true EPR values may be even lower than our estimates. It is, therefore, likely that management action, such as the creation of Marine Protected Areas, is needed to reconstitute the west coast dusky kob population.

Concentrations of trace elements in human milk: Comparisons among women in Argentina, Namibia, Poland, and the United States.

PubMed

Klein, Laura D; Breakey, Alicia A; Scelza, Brooke; Valeggia, Claudia; Jasienska, Grazyna; Hinde, Katie

2017-01-01

Human milk contains essential micronutrients for growth and development during early life. Environmental pollutants, such as potentially toxic metals, can also be transferred to the infant through human milk. These elements have been well-studied, but changing diets and environments and advances in laboratory technology require re-examining these elements in a variety of settings. The aim of this study was to characterize the concentrations of essential and toxic metals in human milk from four diverse populations. Human milk samples (n = 70) were collected in Argentina (n = 21), Namibia (n = 6), Poland (n = 23), and the United States (n = 20) using a standardized mid-feed collection procedure. Milk concentrations of calcium, zinc, iron, copper, manganese, lead, arsenic, and cadmium were determined using inductively coupled plasma mass spectrometry (ICP-MS). We used standard multiple linear regression models to evaluate differences among populations, while including infant age, infant sex, and maternal parity status (multiparous or primiparous) as covariates. Concentrations of all elements, except zinc, varied across populations after controlling for infant age, infant sex, and maternal parity. Calcium and magnesium showed more differences across populations than iron or copper. There were no significant differences among population in zinc concentrations. Mean concentrations of lead, but not arsenic, were low compared to recently published values from other populations. The concentrations of trace elements in human milk are variable among populations. Limitations due to small sample sizes and environmental contamination of some samples prevent us from drawing robust conclusions about the causes of these differences.

Concentrations of trace elements in human milk: Comparisons among women in Argentina, Namibia, Poland, and the United States

PubMed Central

Breakey, Alicia A.; Scelza, Brooke; Valeggia, Claudia; Jasienska, Grazyna; Hinde, Katie

2017-01-01

Human milk contains essential micronutrients for growth and development during early life. Environmental pollutants, such as potentially toxic metals, can also be transferred to the infant through human milk. These elements have been well-studied, but changing diets and environments and advances in laboratory technology require re-examining these elements in a variety of settings. The aim of this study was to characterize the concentrations of essential and toxic metals in human milk from four diverse populations. Human milk samples (n = 70) were collected in Argentina (n = 21), Namibia (n = 6), Poland (n = 23), and the United States (n = 20) using a standardized mid-feed collection procedure. Milk concentrations of calcium, zinc, iron, copper, manganese, lead, arsenic, and cadmium were determined using inductively coupled plasma mass spectrometry (ICP-MS). We used standard multiple linear regression models to evaluate differences among populations, while including infant age, infant sex, and maternal parity status (multiparous or primiparous) as covariates. Concentrations of all elements, except zinc, varied across populations after controlling for infant age, infant sex, and maternal parity. Calcium and magnesium showed more differences across populations than iron or copper. There were no significant differences among population in zinc concentrations. Mean concentrations of lead, but not arsenic, were low compared to recently published values from other populations. The concentrations of trace elements in human milk are variable among populations. Limitations due to small sample sizes and environmental contamination of some samples prevent us from drawing robust conclusions about the causes of these differences. PMID:28817665

Requirements for guidelines systems: implementation challenges and lessons from existing software-engineering efforts

PubMed Central

2012-01-01

Background A large body of work in the clinical guidelines field has identified requirements for guideline systems, but there are formidable challenges in translating such requirements into production-quality systems that can be used in routine patient care. Detailed analysis of requirements from an implementation perspective can be useful in helping define sub-requirements to the point where they are implementable. Further, additional requirements emerge as a result of such analysis. During such an analysis, study of examples of existing, software-engineering efforts in non-biomedical fields can provide useful signposts to the implementer of a clinical guideline system. Methods In addition to requirements described by guideline-system authors, comparative reviews of such systems, and publications discussing information needs for guideline systems and clinical decision support systems in general, we have incorporated additional requirements related to production-system robustness and functionality from publications in the business workflow domain, in addition to drawing on our own experience in the development of the Proteus guideline system (http://proteme.org). Results The sub-requirements are discussed by conveniently grouping them into the categories used by the review of Isern and Moreno 2008. We cite previous work under each category and then provide sub-requirements under each category, and provide example of similar work in software-engineering efforts that have addressed a similar problem in a non-biomedical context. Conclusions When analyzing requirements from the implementation viewpoint, knowledge of successes and failures in related software-engineering efforts can guide implementers in the choice of effective design and development strategies. PMID:22405400

The MAGEC system for spinal lengthening in children with scoliosis: A NICE Medical Technology Guidance.

PubMed

Jenks, Michelle; Craig, Joyce; Higgins, Joanne; Willits, Iain; Barata, Teresa; Wood, Hannah; Kimpton, Christine; Sims, Andrew

2014-12-01

Scoliosis-structural lateral curvature of the spine-affects around four children per 1,000. The MAGEC system comprises a magnetically distractible spinal rod implant and an external remote controller, which lengthens the rod; this system avoids repeated surgical lengthening. Rod implants brace the spine internally and are lengthened as the child grows, preventing worsening of scoliosis and delaying the need for spinal fusion. The Medical Technologies Advisory Committee at the National Institute for Health and Care Excellence (NICE) selected the MAGEC system for evaluation in a NICE medical technologies guidance. Six studies were identified by the sponsor (Ellipse Technologies Inc.) as being relevant to the decision problem. Meta-analysis was used to compare the clinical evidence results with those of one conventional growth rod study, and equal efficacy of the two devices was concluded. The key weakness was selection of a single comparator study. The External Assessment Centre (EAC) identified 16 conventional growth rod studies and undertook meta-analyses of relevant outcomes. Its critique highlighted limitations around study heterogeneity and variations in baseline characteristics and follow-up duration, precluding the ability to draw firm conclusions. The sponsor constructed a de novo costing model showing that MAGEC rods generated cost savings of £9,946 per patient after 6 years, compared with conventional rods. The EAC critiqued and updated the model structure and inputs, calculating robust cost savings of £12,077 per patient with MAGEC rods compared with conventional rods over 6 years. The year of valuation was 2012. NICE issued a positive recommendation as supported by the evidence (Medical Technologies Guidance 18).

Earthquake correlations and networks: A comparative study

NASA Astrophysics Data System (ADS)

Krishna Mohan, T. R.; Revathi, P. G.

2011-04-01

We quantify the correlation between earthquakes and use the same to extract causally connected earthquake pairs. Our correlation metric is a variation on the one introduced by Baiesi and Paczuski [M. Baiesi and M. Paczuski, Phys. Rev. E EULEEJ1539-375510.1103/PhysRevE.69.06610669, 066106 (2004)]. A network of earthquakes is then constructed from the time-ordered catalog and with links between the more correlated ones. A list of recurrences to each of the earthquakes is identified employing correlation thresholds to demarcate the most meaningful ones in each cluster. Data pertaining to three different seismic regions (viz., California, Japan, and the Himalayas) are comparatively analyzed using such a network model. The distribution of recurrence lengths and recurrence times are two of the key features analyzed to draw conclusions about the universal aspects of such a network model. We find that the unimodal feature of recurrence length distribution, which helps to associate typical rupture lengths with different magnitude earthquakes, is robust across the different seismic regions. The out-degree of the networks shows a hub structure rooted on the large magnitude earthquakes. In-degree distribution is seen to be dependent on the density of events in the neighborhood. Power laws, with two regimes having different exponents, are obtained with recurrence time distribution. The first regime confirms the Omori law for aftershocks while the second regime, with a faster falloff for the larger recurrence times, establishes that pure spatial recurrences also follow a power-law distribution. The crossover to the second power-law regime can be taken to be signaling the end of the aftershock regime in an objective fashion.

Habitat Utilization Assessment - Building in Behaviors

NASA Technical Reports Server (NTRS)

Whitmore, Mihriban; Blume, Jennifer

2004-01-01

Habitability, and the associated architectural and design attributes of an environment, is a powerful performance shaping factor. By identifying how inhabitants use an area, we can draw conclusions about what design or architectural attributes cause what behaviors and systematically design in desired human performance. We are analyzing how a crew uses a long duration habitat and work environment during a four-day underwater mission and identifying certain architectural and design attributes that are related to, and potential enablers of, certain crew behaviors. By identifying how inhabitants use the habitat, we can draw conclusions about what habitability attributes cause what behaviors and systematically design in desired human performance (applicable to NASA's Bioastronautics Human Behavior and Performance Critical Path Roadmap question 6.12). This assessment replicates a methodology reported in a chapter titled "Sociokinetic Analysis as a Tool for Optimization of Environmental Design" by C. Adams.' That study collected video imagery of certain areas of a closed habitat during a 91 day test and from that data calculated time spent in different volumes during the mission, and characterized the behaviors occurring in certain habitat volumes thus concluding various rules for design of such habitats. This study assesses the utilization of the Aquarius Habitat, an underwater station, which will support six Aquanauts for a fourteen-day mission during which the crew will perform specific scientific and engineering studies. Video is recorded for long uninterrupted periods of time during the mission and from that data the time spent in each area is calculated. In addition, qualitative and descriptive analysis of the types of behaviors in each area is performed with the purpose of identifying any behaviors that are not typical of a certain area. If a participant uses an area in a way different from expected, a subsequent analysis of the features of that area may result in conclusions of performance shaping factors. With the addition of this study, we can make comparisons between the two different habitats and begin drawing correlation judgments about design features and behavior. Ideally, this methodology should be repeated in additional Aquarius missions and other analog environments because the real information will come from comparisons between habitats.

What do we really know about the signalling role of plumage colour in blue tits? A case study of impediments to progress in evolutionary biology.

PubMed

Parker, Timothy H

2013-08-01

Evolutionary biologists seek to explain the origin and maintenance of phenotypes, and a substantial portion of this research is accomplished by thorough study of individual species. For instance, many researchers study individual species to understand evolution of ornamental traits which appear to be products of sexual selection. I explored our understanding of sexual ornaments in a well-studied vertebrate species that may serve as a case study for research programs in evolutionary biology. I attempted to located all published papers examining plumage colour and variables related to sexual selection hypotheses in a common European songbird, the blue tit (Cyanistes caeruleus). Researchers have estimated over 1200 statistical relationships with plumage colour of blue tits in 52 studies. However, of the approximately 1000 main-effect relationships from the 48 studies that are candidates for inclusion in this meta-analysis, more than 400 were reported without details of strength and direction. Circumstantial evidence suggests that an unknown number of other estimated effects remain unpublished. Missing information is a substantial barrier to interpretation of these papers and to meta-analytic synthesis. Examination and analysis of funnel plots indicated that unpublished effects may be a biased sample of all effects, especially for comparisons of plumage colour to age and individual quality, and possibly also to measures of mate choice. Further, type I error was likely elevated by the large number of statistical comparisons evaluated, the frequent use of iterative model-building procedures, and a willingness to interpret a wide variety of results as support for a hypothesis. Type I errors were made more problematic because blue tit plumage researchers only rarely have attempted to replicate important findings in their own work or that of others. Replication is essential to drawing robust scientific conclusions, especially in probabilistic systems with moderate to weak effects or a likelihood of bias. Last, researchers studying blue tit plumage have often developed ad hoc explanations for deviations of results from their predictions. Revising hypotheses in light of data is appropriate, but these revised hypotheses were rarely tested with new data. The only highly robust conclusion supported by meta-analysis is that male blue tits have plumage that reflects more light in the ultraviolet and yellow wavelengths than the plumage of females. Various other effects, including condition-dependence of plumage colour expression and a tendency for females to adjust the sex ratio of their offspring in response to male colour, remain uncertain. These obstacles to progress in the blue tit plumage literature are likely common in evolutionary biology, and so I recommend changes to incentive structures which may improve progress towards scientific understanding in this discipline. © 2012 The Authors. Biological Reviews © 2012 Cambridge Philosophical Society.

Gender identity and autism spectrum disorders.

PubMed

van Schalkwyk, Gerrit I; Klingensmith, Katherine; Volkmar, Fred R

2015-03-01

In this review, we briefly summarize much of the existing literature on gender-related concerns and autism spectrum disorders (ASD), drawing attention to critical shortcomings in our current understanding and potential clinical implications. Some authors have concluded that gender identity disorder (GID), or gender dysphoria (GD), is more common in individuals with ASD, providing a range of potential explanations. However, existing literature is quantitatively limited, and our capacity to draw conclusions is further complicated by conceptual challenges regarding how gender identity is best understood. Discourses that emphasize gender as a component of identity formation are gaining prominence and seem particularly salient when applied to ASD. Individuals with ASD should enjoy equal rights with regard to treatment for gender dysphoria. Clinicians may be able to assist individuals in understanding this aspect of their identity by broadening the social frame and facilitating an exploration of gender roles.

A bottom-up strategy for establishment of EER in three Nordic countries - the role of networks

NASA Astrophysics Data System (ADS)

Edström, Kristina; Kolmos, Anette; Malmi, Lauri; Bernhard, Jonte; Andersson, Pernille

2018-03-01

This paper investigates the emergence of an engineering education research (EER) community in three Nordic countries: Denmark, Finland and Sweden. First, an overview of the current state of Nordic EER authorship is produced through statistics on international publication. Then, the history of EER and its precursor activities is described in three national narratives. These national storylines are tied together in a description of recent networking activities, aiming to strengthen the EER communities on the Nordic level. Taking these three perspectives together, and drawing on concepts from community of practice theory, network theory and learning network theory, we discuss factors behind the differences in the countries, and draw some conclusions about implications for networking activities in a heterogeneous community. Further, we discuss the role of networks for affording a joint identity.

The influence of education on performance of adults on the Clock Drawing Test

PubMed Central

de Noronha, Ísis Franci Cavalcanti; Barreto, Simone dos Santos; Ortiz, Karin Zazo

2018-01-01

ABSTRACT The Clock Drawing Test (CDT) is an important instrument for screening individuals suspected of having cognitive impairment. Objective: To determine the influence of education on the performance of healthy adults on the CDT. Methods: A total of 121 drawings by healthy adults without neurological complaints or impairments were analysed. Participants were stratified by educational level into 4 subgroups: 27 illiterate adults, 34 individuals with 1-4 years of formal education, 30 with 5-11 years, and 30 adults with >11 years' formal education. Scores on the CDT were analyzed based on a scale of 1-10 points according to the criteria of Sunderland et al. (1989).¹ The Kruskal-Wallis test was applied to compare the different education groups. Tukey's multiple comparisons test was used when a significant factor was found. Results: Although scores were higher with greater education, statistically significant differences on the CDT were found only between the illiterate and other educated groups. Conclusion: The CDT proved especially difficult for illiterate individuals, who had lower scores. These results suggest that this screening test is suitable for assessing mainly visuoconstructional praxis and providing an overall impression of cognitive function among individuals, independently of years of education. PMID:29682235

Critical ionization velocity experiments in space

NASA Astrophysics Data System (ADS)

Lai, Shu T.; Murad, Edmond

1989-07-01

Space experiments to test the critical ionization velocity (CIV) theory have, on the whole, yielded negative results, with two notable exceptions. The results of all the experiments are analyzed with a view towards either optimizing or drawing conclusions about the conditions which lead to the propagation of CIV. In particular, four aspects of the conditions are considered: (1) beam injection angle with the ambient magnetic field in the ionosphere; (2) length of a CIV discharge region in a conical beam; (3) collisional ionization of the neutrals; and (4) chemiionization processes. The analysis leads to the conclusion that using the exhaust of the Shuttle engines may be the best way for testing CIV.

Long bone robustness during growth: A cross-sectional pQCT examination of children and young adults aged 5-29years.

PubMed

Rantalainen, Timo; Weeks, Benjamin K; Nogueira, Rossana C; Beck, Belinda R

2016-12-01

Skeletal robustness (cross-section size relative to length) is associated with stress fractures in adults, and appears to explain the high incidence of distal radius fractures in adolescents. However, little is known about the ontogeny of long bone robustness during the first three decades of life. Therefore, we explored the ontogeny of tibial, fibular, ulnar and radial robustness in a cross-sectional sample of 5 to 29year-old volunteers of both sexes. Peripheral quantitative computed tomography (pQCT) was used to evaluate cross-sections of the leg (4%, 14%, 38% and 66%), and forearm (4%, and 66%) in N=432 individuals. Robustness was evaluated as the total bone area divided by bone length. Differences between age-groups, sexes, and age-group×sex interactions were evaluated with ANOVA with Tukey's post hocs where appropriate. Most bone sites exhibited more robust bones in men than women (P<0.001 to 0.02), and in older age-groups than younger (P<0.001). Sex×age-group interaction was observed at the 66% and 38% tibia sites with robustness increasing more with age in men than in women (P=0.006 to 0.042). Post-hoc analyses indicated no sex differences prior to 13years-of-age, and notable exceptions to increasing robustness with age at the 4% radial and 66% tibial sites, which exhibited reduced robustness in age groups close to peak height velocity. In conclusion, the present results suggest that very little sexual dimorphism in long bone robustness exists prior to puberty, and that divergence occurs primarily after cessation of longitudinal growth. A period of relative diaphyseal slenderness was identified at age-groups coinciding with the adolescent growth spurt, which may be related to the relatively high incidence of frank and stress fracture in adolescents. Copyright © 2016 Elsevier Inc. All rights reserved.

Temperature measurement with industrial color camera devices

NASA Astrophysics Data System (ADS)

Schmidradler, Dieter J.; Berndorfer, Thomas; van Dyck, Walter; Pretschuh, Juergen

1999-05-01

This paper discusses color camera based temperature measurement. Usually, visual imaging and infrared image sensing are treated as two separate disciplines. We will show, that a well selected color camera device might be a cheaper, more robust and more sophisticated solution for optical temperature measurement in several cases. Herein, only implementation fragments and important restrictions for the sensing element will be discussed. Our aim is to draw the readers attention to the use of visual image sensors for measuring thermal radiation and temperature and to give reasons for the need of improved technologies for infrared camera devices. With AVL-List, our partner of industry, we successfully used the proposed sensor to perform temperature measurement for flames inside the combustion chamber of diesel engines which finally led to the presented insights.

Entangling distant resonant exchange qubits via circuit quantum electrodynamics

NASA Astrophysics Data System (ADS)

Srinivasa, V.; Taylor, J. M.; Tahan, Charles

2016-11-01

We investigate a hybrid quantum system consisting of spatially separated resonant exchange qubits, defined in three-electron semiconductor triple quantum dots, that are coupled via a superconducting transmission line resonator. Drawing on methods from circuit quantum electrodynamics and Hartmann-Hahn double resonance techniques, we analyze three specific approaches for implementing resonator-mediated two-qubit entangling gates in both dispersive and resonant regimes of interaction. We calculate entangling gate fidelities as well as the rate of relaxation via phonons for resonant exchange qubits in silicon triple dots and show that such an implementation is particularly well suited to achieving the strong coupling regime. Our approach combines the favorable coherence properties of encoded spin qubits in silicon with the rapid and robust long-range entanglement provided by circuit QED systems.

Biomarkers of Exposure to Toxic Substances. Volume 3: Proteomics, Biomarkers to Kidney and Organ Damage

DTIC Science & Technology

2009-05-01

not reveal any interesting proteins (Data is not shown). All of the spots turned out to be keratins. 3.1.2.2 Conclusions on puromycin toxicity...hamster) Odorant-binding protein precursor - Rattus norvegicus (Rat) 0.543 2.105 Oleandomycin polyketide synthase , modules 5...Using Government drawings, specifications, or other data included in this document for any purpose other than Government procurement does not

[Day-care mother--a successful model of child rearing?].

PubMed

Schetelig, H

1977-02-17

The scientific reports published so far on the project "day care mothering" do not allow to draw scientific conclusions, whether this educational model can achieve nearly equal results as family education. The author critisises, that such a clame is made. It seems necessary, to pay more importance to the function of the mother for her children, to give the children a sound emotional basis for their future development.

The role of social media in reducing stigma and discrimination.

PubMed

Betton, Victoria; Borschmann, Rohan; Docherty, Mary; Coleman, Stephen; Brown, Mark; Henderson, Claire

2015-06-01

This editorial explores the implications of social media practices whereby people with mental health problems share their experiences in online public spaces and challenge mental health stigma. Social media enable individuals to bring personal experience into the public domain with the potential to affect public attitudes and mainstream media. We draw tentative conclusions regarding the use of social media by campaigning organisations. © The Royal College of Psychiatrists 2015.

The Role of Work Experiences in College Student Leadership Development: Evidence from a National Dataset and a Text Mining Approach to Examining Beliefs about Leadership

ERIC Educational Resources Information Center

Lewis, Jonathan S.

2017-01-01

Paid employment is one of the most common extracurricular activities among full-time undergraduates, and an array of studies has attempted to measure its impact. Methodological concerns with the extant literature, however, make it difficult to draw reliable conclusions. Furthermore, the research on working college students has little to say about…

Technologies Underlying Weapons of Mass Destruction

DTIC Science & Technology

1993-12-01

Chemica / Agents (Aberdee~ MD: Edgewood Arsenal Special Tectical Repom 1969). 20 Alan R. Pittaway, “The Difficulty of Converting Pesticide Plants...completion. Libyan government officials adamantly insisted that the Rabta facility was a pharmaceutical plant, designated Pharma -150. Yet the factory was...the control unit, burn-off unit, corrosion-proof Iining on pipes, and escape routes) make it possible to draw the conclusion that ‘ Pharma 150’ is a

Assaying Benefits of Poly[styrene-4-(trimethylammonium)methyl Triiodide] in Respiratory Protection Devices

DTIC Science & Technology

2009-12-01

common laboratory mouse, Mus musculus , and treated and mechanically equivalent untreated filter media to measure infection rates as a function of...to determine viable counts. Data noise in the control experiment prevented drawing a firm conclusion but loss of viability in the aerosol phase ...protection, Triosyn U U U UU 35 Joseph Wander Reset iii TABLE OF CONTENTS Section Page 1.0 Overview

Translations on Eastern Europe Political, Sociological, and Military Affairs, Number 1470

DTIC Science & Technology

1977-11-08

8217 freedom. Comrade Enver Hoxha draws attention to the fact that the Khrushchevite revisionists tried to impose this attitude toward imperialism and...are being repeated by the new opportunists, it is impossible for one’s attention not to be drawn by the Marxist-Leninist conclusion, based on...applause, congratulations and praise. Attentively following and analyzing the activity of the modern revisionists, Comrade Enver Hoxha, in addition to

Revisiting the Benefits of Higher Education. A Report by the Bedford Group for Lifecourse and Statistical Studies, Institute of Education.

ERIC Educational Resources Information Center

Bynner, John; Dolton, Peter; Feinstein, Leon; Makepeace, Gerry; Malmberg, Lars; Woods, Laura

An earlier report presented preliminary findings on the wider benefits of higher education in England, drawing on data collected at age 33 from the National Child Development Study, based on a cohort born in 1958 and a sample of more than 16,000. This report updates the earlier conclusions through new findings from a more extensive analysis…

The Importance of Being Colorful and Able to Fly: Interpretation and Implications of Children's Statements on Selected Insects and Other Invertebrates

ERIC Educational Resources Information Center

Breuer, Gabriele B.; Schlegel, Jürg; Kauf, Peter; Rupf, Reto

2015-01-01

Children have served as research subjects in several surveys on attitudes to insects and invertebrates. Most of the studies have used quantitative scoring methods to draw conclusions. This paper takes a different approach as it analyzes children's free-text comments to gain an understanding of their viewpoints. A total of 246 children aged 9-13…

EPA releases progress report on hydraulic fracturing study

NASA Astrophysics Data System (ADS)

Showstack, Randy

2013-01-01

The U.S. Environmental Protection Agency (EPA) provided a 21 December progress report on its ongoing national study about the potential impacts of hydraulic fracturing on drinking water resources. The agency said that a draft of the congressionally requested study will be released in 2014 for public and peer review and that its progress report does not draw conclusions about the potential impacts of hydraulic fracturing, often referred to as fracking.

Assessment of the Principal Needs of the Spanish Speaking in Chicago. Findings, Conclusions, and Recommendations. Volume I of a Two-Volume Report.

ERIC Educational Resources Information Center

Vasquez Associates Ltd., Milwaukee, WI.

The main portion of this study is devoted to the determination of needs for health, education and social welfare services of the Spanish speaking in Chicago, and to draw inferences about the degree to which Department of Health, Education and Welfare (HEW) funds and services in Chicago are reaching this specific minority and the extent to which…

Induced Insecurity: Understanding the Potential Pitfalls in Developing Theater Campaign Plans

DTIC Science & Technology

2015-06-11

effective partnerships that meet outlined in higher- level strategic guidance . 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. UMITATION OF... effective partnerships that meet the desired end states outlined in higher-level strategic guidance. DEDICATION To the millions of men and women who...and draw conclusions, it does not always prove to be an effective means of predicting the outcome of current or future events. In addition, the

Differential equations in airplane mechanics

NASA Technical Reports Server (NTRS)

Carleman, M T

1922-01-01

In the following report, we will first draw some conclusions of purely theoretical interest, from the general equations of motion. At the end, we will consider the motion of an airplane, with the engine dead and with the assumption that the angle of attack remains constant. Thus we arrive at a simple result, which can be rendered practically utilizable for determining the trajectory of an airplane descending at a constant steering angle.

The impact of scienceware and foundations on students' attitudes towards science and science classes

NASA Astrophysics Data System (ADS)

Stratford, Steven J.; Finkel, Elizabeth A.

1996-03-01

In this paper, we describe changes in students' ideas about science classes, attitudes about science, and motivations for studying science, in a classroom designed to support projectbased science learing. Using a survey designed to provide a measure of students' attitudes towards science classes and science, we have compared students enrolled in a traditional high school biology course, with students enrolled in an integrated, project-based science course called Foundations I. Survey responses were analyzed to look at differences between and within two groups of students over the course of one school year. In general, the results of this study suggest that providing students with opportunities to collect and analyze their own data in science classes results in a change in students' ideas about science classrooms. Foundations I students' increased tendency to agree with statements about `using information,' `drawing conclusions,' and `thinking about problems,' implies a change in their understanding of what it means to do science in school. These students, in contrast to students in the traditional Biology course, no longer describe their science experience as one of memorization, textbook reading, and test taking. Instead they see science class as a place in which they can collect data, draw conclusions, and formulate and solve problems.

Artificial muscles' enrichment text: Chemical Literacy Profile of pre-service teachers

NASA Astrophysics Data System (ADS)

Hernani, Ulum, Luthfi Lulul; Mudzakir, Ahmad

2017-08-01

This research aims to determine the profile of chemical literacy abilities of pre-service teachers based on scientific attitudes and scientific competencies in PISA 2015 through individualized learning by using an artificial muscle context based-enrichment book. This research uses descriptive method, involving 20 of the 90 randomly selected population. This research uses a multiple-choice questions instrument. The result of this research are : 1) in the attitude aspects of interest in science and technology, valuing scientific approaches to inquiry, and environmental awareness, the results obtained respectively for 90%, 80%, and 30%. 2) for scientific competence of apply appropriate scientific knowledge, identify models and representations, make appropriate predictions, and explain the potential implications of scientific knowledge for society, the results obtained respectively for 30%, 50%, 60%, and 55%. 3) For scientific competence of identify the question explored in a given scientific study and distinguish questions that could be investigated scientifically, the results obtained respectively for 30 % and 50%. 4) For scientific competence of transform data from one representation to another and draw appropriate conclusions, the results obtained respectively for 60% and 45%. Based on the results, which need to be developed in pre-service chemistry teachers are environmental awareness, apply appropriate scientific knowledge, identify the question explored in a given scientific study, and draw appropriate conclusions.

Adenomyosis: a life-cycle approach.

PubMed

Benagiano, Giuseppe; Brosens, Ivo; Habiba, Marwan

2015-03-01

The life-cycle approach to endometriosis highlighted unexpected features of the condition; the same approach was therefore applied to gain insight into the clinical features of adenomyosis and to draw a comparison with endometriosis. This is possible today thanks to new imaging techniques enabling non-invasive diagnosis of adenomyosis. The specificity and sensitivity of magnetic resonance imaging and transvaginal ultrasound remain uncertain. Unlike endometriosis, little information is available on the presence of classic adenomyosis in adolescents, except for rare cystic forms that may not represent the true disease. Adenomyosis is most likely to affect adult women, although most reported incidences are still based on post-hysterectomy studies, and are affected by diligence in histopathologic diagnosis and the adopted cut-off point. The traditionally accepted associations of adult adenomyosis, such as multiparity, a link to infertility and its effect on pregnancy are uncertain. Active adenomyosis has been found in pre- and peri-menopausal women and in postmenopausal women receiving tamoxifen. In conclusion, major diagnostic limitations and the systematic bias of hysterectomy make it difficult to draw firm conclusions from existing evidence. In addition, no information is available on the natural history of adenomyosis and no study has systematically evaluated its existence in adolescents. Copyright © 2014 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Controversies relating to the management of acromioclavicular joint dislocations.

PubMed

Modi, C S; Beazley, J; Zywiel, M G; Lawrence, T M; Veillette, C J H

2013-12-01

The aim of this review is to address controversies in the management of dislocations of the acromioclavicular joint. Current evidence suggests that operative rather than non-operative treatment of Rockwood grade III dislocations results in better cosmetic and radiological results, similar functional outcomes and longer time off work. Early surgery results in better functional and radiological outcomes with a reduced risk of infection and loss of reduction compared with delayed surgery. Surgical options include acromioclavicular fixation, coracoclavicular fixation and coracoclavicular ligament reconstruction. Although non-controlled studies report promising results for arthroscopic coracoclavicular fixation, there are no comparative studies with open techniques to draw conclusions about the best surgical approach. Non-rigid coracoclavicular fixation with tendon graft or synthetic materials, or rigid acromioclavicular fixation with a hook plate, is preferable to fixation with coracoclavicular screws owing to significant risks of loosening and breakage. The evidence, although limited, also suggests that anatomical ligament reconstruction with autograft or certain synthetic grafts may have better outcomes than non-anatomical transfer of the coracoacromial ligament. It has been suggested that this is due to better restoration horizontal and vertical stability of the joint. Despite the large number of recently published studies, there remains a lack of high-quality evidence, making it difficult to draw firm conclusions regarding these controversial issues.

Framework for assessing causality of air pollution-related health effects for reviews of the National Ambient Air Quality Standards.

PubMed

Owens, Elizabeth Oesterling; Patel, Molini M; Kirrane, Ellen; Long, Thomas C; Brown, James; Cote, Ila; Ross, Mary A; Dutton, Steven J

2017-08-01

To inform regulatory decisions on the risk due to exposure to ambient air pollution, consistent and transparent communication of the scientific evidence is essential. The United States Environmental Protection Agency (U.S. EPA) develops the Integrated Science Assessment (ISA), which contains evaluations of the policy-relevant science on the effects of criteria air pollutants and conveys critical science judgments to inform decisions on the National Ambient Air Quality Standards. This article discusses the approach and causal framework used in the ISAs to evaluate and integrate various lines of scientific evidence and draw conclusions about the causal nature of air pollution-induced health effects. The framework has been applied to diverse pollutants and cancer and noncancer effects. To demonstrate its flexibility, we provide examples of causality judgments on relationships between health effects and pollutant exposures, drawing from recent ISAs for ozone, lead, carbon monoxide, and oxides of nitrogen. U.S. EPA's causal framework has increased transparency by establishing a structured process for evaluating and integrating various lines of evidence and uniform approach for determining causality. The framework brings consistency and specificity to the conclusions in the ISA, and the flexibility of the framework makes it relevant for evaluations of evidence across media and health effects. Published by Elsevier Inc.

Assessing treatment effects in older breast cancer patients: systematic review of observational research methods.

PubMed

de Glas, N A; Kiderlen, M; de Craen, A J M; Hamaker, M E; Portielje, J E A; van de Velde, C J H; Liefers, G J; Bastiaannet, E

2015-03-01

Solid evidence of treatment effects in older women with breast cancer is lacking, as they are generally underrepresented in randomized clinical trials on which guideline recommendations are based. An alternative way to study treatment effects in older patients could be to use data from observational studies. However, using appropriate methods in analyzing observational data is a key condition in order to draw valid conclusions, as directly comparing treatments generally results in biased estimates due to confounding by indication. The aim of this systematic review was to investigate the methods that have been used in observational studies that assessed the effects of breast cancer treatment on survival, breast cancer survival and recurrence in older patients (aged 65 years and older). Studies were identified through systematic review of the literature published between January 1st 2009 and December 13th 2013 in the PubMed database and EMBASe. Finally, 31 studies fulfilled the inclusion criteria. Of these, 22 studies directly compared two treatments. Fifteen out of these 22 studies addressed the problem of confounding by indication, while seven studies did not. Nine studies used some form of instrumental variable analysis. In conclusion, the vast majority of observational studies that investigate treatment effects in older breast cancer patients compared treatments directly. These studies are therefore likely to be biased. Observational research will be essential to improve treatment and outcome of older breast cancer patients, but the use of accurate methods is essential to draw valid conclusions from this type of data. Copyright © 2015 Elsevier Ltd. All rights reserved.

Highly robust thin-film composite pressure retarded osmosis (PRO) hollow fiber membranes with high power densities for renewable salinity-gradient energy generation.

PubMed

Han, Gang; Wang, Peng; Chung, Tai-Shung

2013-07-16

The practical application of pressure retarded osmosis (PRO) technology for renewable blue energy (i.e., osmotic power generation) from salinity gradient is being hindered by the absence of effective membranes. Compared to flat-sheet membranes, membranes with a hollow fiber configuration are of great interest due to their high packing density and spacer-free module fabrication. However, the development of PRO hollow fiber membranes is still in its infancy. This study aims to open up new perspectives and design strategies to molecularly construct highly robust thin film composite (TFC) PRO hollow fiber membranes with high power densities. The newly developed TFC PRO membranes consist of a selective polyamide skin formed on the lumen side of well-constructed Matrimid hollow fiber supports via interfacial polymerization. For the first time, laboratory PRO power generation tests demonstrate that the newly developed PRO hollow fiber membranes can withstand trans-membrane pressures up to 16 bar and exhibit a peak power density as high as 14 W/m(2) using seawater brine (1.0 M NaCl) as the draw solution and deionized water as the feed. We believe that the developed TFC PRO hollow fiber membranes have great potential for osmotic power harvesting.

Monitoring and evaluating transition and sustainability of donor-funded programs: Reflections on the Avahan experience.

PubMed

Bennett, Sara; Ozawa, Sachiko; Rodriguez, Daniela; Paul, Amy; Singh, Kriti; Singh, Suneeta

2015-10-01

In low and middle-income countries, programs funded and implemented by international donors frequently transition to local funding and management, yet such processes are rarely evaluated. We reflect upon experience evaluating the transition of a large scale HIV/AIDS prevention program in India, known as Avahan, in order to draw lessons about transition evaluation approaches and implementation challenges. In terms of conceptualizing the transition theory, the evaluation team identified tensions between the idea of institutionalizing key features of the Avahan program, and ensuring program flexibility to promote sustainability. The transition was planned in three rounds allowing for adaptations to transition intervention and program design during the transition period. The assessment team found it important to track these changes in order to understand which strategies and contextual features supported transition. A mixed methods evaluation was employed, combining semi-structured surveys of transitioning entities (conducted pre and post transition), with longitudinal case studies. Qualitative data helped explain quantitative findings. Measures of transition readiness appeared robust, but we were uncertain of the robustness of institutionalization measures. Finally, challenges to the implementation of such an evaluation are discussed. Given the scarceness of transition evaluations, the lessons from this evaluation may have widespread relevance. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Introducing Jus ante Bellum as a cosmopolitan approach to humanitarian intervention

PubMed Central

Brown, Garrett Wallace; Bohm, Alexandra

2015-01-01

Cosmopolitans often argue that the international community has a humanitarian responsibility to intervene militarily in order to protect vulnerable individuals from violent threats and to pursue the establishment of a condition of cosmopolitan justice based on the notion of a ‘global rule of law’. The purpose of this article is to argue that many of these cosmopolitan claims are incomplete and untenable on cosmopolitan grounds because they ignore the systemic and chronic structural factors that underwrite the root causes of these humanitarian threats. By way of examining cosmopolitan arguments for humanitarian military intervention and how systemic problems are further ignored in iterations of the Responsibility to Protect, this article suggests that many contemporary cosmopolitan arguments are guilty of focusing too narrowly on justifying a responsibility to respond to the symptoms of crisis versus demanding a similarly robust justification for a responsibility to alleviate persistent structural causes. Although this article recognizes that immediate principles of humanitarian intervention will, at times, be necessary, the article seeks to draw attention to what we are calling principles of Jus ante Bellum (right before war) and to stress that current cosmopolitan arguments about humanitarian intervention will remain insufficient without the incorporation of robust principles of distributive global justice that can provide secure foundations for a more thoroughgoing cosmopolitan condition of public right. PMID:29708128

Resilience 2.0: social media use and (self-)care during the 2011 Norway attacks

PubMed Central

2015-01-01

Departing from the understanding that resilience is a technique of self-organization during emergencies, this article provides a study on the way in which the use of social media influenced and engendered societal resilience practices during the 2011 Norway attacks. It builds on the concepts of governmentality and mediality to discuss how the interplay between social media and its users created new forms of self-initiated and mediated emergency governance. Empirically, it draws on material from 20 in-depth interviews with Norwegians who explained and reflected upon their social media use during the attacks. The article presents an overview of the different functions that social media assumed in the process of dealing with the attacks and discusses these vis-à-vis their related challenges. It draws conclusions about the way in which resilience practices and the resilient subject are influenced by the networked character of 2.0 technologies. PMID:29708120

Resilience 2.0: social media use and (self-)care during the 2011 Norway attacks.

PubMed

Kaufmann, Mareile

2015-10-01

Departing from the understanding that resilience is a technique of self-organization during emergencies, this article provides a study on the way in which the use of social media influenced and engendered societal resilience practices during the 2011 Norway attacks. It builds on the concepts of governmentality and mediality to discuss how the interplay between social media and its users created new forms of self-initiated and mediated emergency governance. Empirically, it draws on material from 20 in-depth interviews with Norwegians who explained and reflected upon their social media use during the attacks. The article presents an overview of the different functions that social media assumed in the process of dealing with the attacks and discusses these vis-à-vis their related challenges. It draws conclusions about the way in which resilience practices and the resilient subject are influenced by the networked character of 2.0 technologies.

Gender Identity and Autism Spectrum Disorders

PubMed Central

van Schalkwyk, Gerrit I.; Klingensmith, Katherine; Volkmar, Fred R.

2015-01-01

In this review, we briefly summarize much of the existing literature on gender-related concerns and autism spectrum disorders (ASD), drawing attention to critical shortcomings in our current understanding and potential clinical implications. Some authors have concluded that gender identity disorder (GID), or gender dysphoria (GD), is more common in individuals with ASD, providing a range of potential explanations. However, existing literature is quantitatively limited, and our capacity to draw conclusions is further complicated by conceptual challenges regarding how gender identity is best understood. Discourses that emphasize gender as a component of identity formation are gaining prominence and seem particularly salient when applied to ASD. Individuals with ASD should enjoy equal rights with regard to treatment for gender dysphoria. Clinicians may be able to assist individuals in understanding this aspect of their identity by broadening the social frame and facilitating an exploration of gender roles. PMID:25744543

Obesogenic environments: environmental approaches to obesity prevention.

PubMed

Lipek, Tobias; Igel, Ulrike; Gausche, Ruth; Kiess, Wieland; Grande, Gesine

2015-05-01

Childhood obesity is a major concern for public health. There are multiple factors (e.g., genetic, social, and environmental) that contribute to unhealthy weight gain. Drawing from findings on "obesogenic environments" and core principles of preventive strategies to reduce health inequalities, this paper gives an overview of recent childhood prevention programs that target aspects of the physical environment ("environmental changes"). Out of the ten reviews we screened (including more than 300 studies), we identified very few that addressed aspects of the environment. We focus here on 14 programs that follow different approaches to environmental changes (e.g., access to/quality of playgrounds, changes in school cafeterias). Altering the environment offers opportunities for healthier behaviors and seems to be an effective strategy to prevent childhood obesity. However, the evaluation of those (mostly) multidimensional interventions does not allow drawing firm conclusions about the single effect of environmental changes. We conclude that obesity prevention programs should combine person-based and environmental approaches.

Why consent may not be needed for organ procurement.

PubMed

Delaney, James; Hershenov, David B

2009-08-01

Most people think it is wrong to take organs from the dead if the potential donors had previously expressed a wish not to donate. Yet people respond differently to a thought experiment that seems analogous in terms of moral relevance to taking organs without consent. We argue that our reaction to the thought experiment is most representative of our deepest moral convictions. We realize not everyone will be convinced by the conclusions we draw from our thought experiment. Therefore, we point out that the state ignores consent in performing mandatory autopsies in some cases. If readers are willing to give up the permissibility of mandatory autopsies, we then offer some metaphysical arguments against posthumous harm. Drawing upon claims about bodies ceasing to exist at death and Epicurean-inspired arguments against posthumous interests, we make a case for an organ conscription policy which respects fundamental liberal principles of autonomy, bodily integrity, and property.

Convex Arrhenius plots and their interpretation

PubMed Central

Truhlar, Donald G.; Kohen, Amnon

2001-01-01

This paper draws attention to selected experiments on enzyme-catalyzed reactions that show convex Arrhenius plots, which are very rare, and points out that Tolman's interpretation of the activation energy places a fundamental model-independent constraint on any detailed explanation of these reactions. The analysis presented here shows that in such systems, the rate coefficient as a function of energy is not just increasing more slowly than expected, it is actually decreasing. This interpretation of the data provides a constraint on proposed microscopic models, i.e., it requires that any successful model of a reaction with a convex Arrhenius plot should be consistent with the microcanonical rate coefficient being a decreasing function of energy. The implications and limitations of this analysis to interpreting enzyme mechanisms are discussed. This model-independent conclusion has broad applicability to all fields of kinetics, and we also draw attention to an analogy with diffusion in metastable fluids and glasses. PMID:11158559